baber/WOPTO huggingface dataset:
Patent CA-2243826-A1 (CA)
Title: Synthesis of acyclic nucleosides
Inventor: ZHOU XIAO-XIONG
IPC: C07D473/18
Filed: 1997-02-14
Abstract: A method for preparing enhanced bioavailability antiviral compounds of formula (I) where one of R1 and R2 is -C(O)CH(CH(CH3)2)NH2 or -C(O)CH(CH(CH3)CH2CH3)NH2 and the other of R1 and R2 is -C(O)C3-C21 saturated or monounsaturated, optionally substituted alkyl; and R3 is OH or H, the method comprising: A) the monodeacylation of a diacylated compound corresponding to formula (I) wherein R1 and R2 are both -C(O)CH(CH(CH3)2)NH2 or -C(O)CH(CH(CH3)CH2CH3)NH2 (which are optionally N-protected) or R1 and R2 are both -C(=O)C3-C21, saturated or monounsaturated, optionally substituted alkyl; B) acylating the thus liberated side chain 4-hydroxy or side chain 2-hydroxymethyl group with the corresponding -C(O)CH(CH(CH3)2)NH2 or -C(O)CH(CH(CH3)CH2CH3)NH2 or -C(=O)C3-C21, saturated or monounsaturated, optionally substituted alkyl to thereby produce a compound of formula (I); and C) deprotecting as necessary.
Patent CA-2243829-A1 (CA)
Title: Method and device for the simultaneous isolation of genomic dna and high-purity total rna
Inventor: BENDZKO PETER
IPC: B01F35/60
Filed: 1996-07-16
Abstract: The invention concerns a method and device for the rapid, simultaneous isolation of genomic desoxyribonucleic acid (DNA) and cellular total ribonucleic acid (RNA), free of genomic DNA  from various starting materials. The fields of application are molecular biology, biochemistry, gene technology (in particular gene therapy), medicine, biomedical diagnosis, veterinary medicine, food analysis and all related fields. The method proposed is characterized in that materials containing DNA and RNA are lysed in a special buffer, the lysate incubated with a mineral carrier, the carrier with the DNA bound to it separated off and washed with buffer solution, and the DNA subsequently separated from the carrier with a buffer of lower salt concentration. The lysate left after separating off the DNA  bound to the carrier is mixed with phenol, chloroform and sodium acetate in defined proportions, the phases allowed to separate, and the total RNA precipitated from the aqueous phase by adding isopropanol. Lysis is carried out using buffers containing chaotropic salts with a high ionic strength. Lysis of the material and bonding of the genomic DNA to the carrier are both carried out in the same buffer. Both the lysis of the starting material and all necessary washing steps are carried out in an apparatus which makes it possible to process 12 samples in parallel.
Patent CA-2244432-A1 (CA)
Title: Dispositif de transfert entre une premiere enceinte de prechauffage et une seconde enceinte de rechauffage
Inventor: AUDEBERT JEAN-CLAUDE
IPC: F27D3/00
Filed: 1998-07-28
Abstract: Dispositif pour le traitement de produits sidérurgiques au sein d'enceintes métallurgiques comportant une enceinte de préchauffage recevant des produits sidérurgiques tels que billettes, blooms, brames, ébauches, provenant d'un site de production situé en amont, une enceinte de réchauffage recevant lesdits produits provenant de ladite enceinte de préchauffage qui sont délivrés par cette dernièr e par un dispositif de transfert, positionné entre lesdites enceintes de préchauffage et de réchauffage et un site de production auquel sont délivrés lesdits produits sorta nt de l'enceinte de réchauffage dans lequel, ledit dispositif de transfert comporte un châssis muni d'un assemblage constitué par la juxtaposition d'une pluralité de longerons mobiles et éventuellement d'une pluralité de rouleaux, ceux-ci étant positionnés entre l'enceinte de préchauffage et l'enceinte de réchauffage, et à l'extrémité d'une ligne de transfert des produits sidérurgiques, lesdits longerons mobiles coopérant à la f ois avec un châssis de levage/dépose et avec un châssis de translation avant/arrière , lesdits châssis de levage/dépose et de translation avant/arrière étant munis de moyens, permettant de faire décrire un mouvement de pas rectangulaire auxdits longerons mobiles, de manière à assurer le transfert des produits sidérurgiques entre lesdites enceintes de réchauffage.
Patent CA-2244972-A1 (CA)
Title: Hot-melt adhesives with copolymer base having epoxy functions
Inventor: RADIGON ERIC
IPC: C09J133/14
Filed: 1997-11-18
Abstract: The invention concerns a hot-melt adhesive with a base of a copolymer (A) comprising the following units: ethylene, optionally a monomer selected among vinyl esters or alkyl (meth) acrylate, at least an unsaturate epoxy. It can be formularized with a tackifying resin and a wax. Ethylene copolymers, n-butyl acrylate and glycidyl methacrylate are advantageously used.
Patent CA-2249366-A1 (CA)
Title: Novel isoflavone-enriched soy protein product and method for its manufacture
Inventor: KERR PHILLIP SCOTT
IPC: A23L11/00
Filed: 1997-04-08
Abstract: This invention relates to a novel isoflavone-enriched soy protein product and a method used for its manufacture. The finished soy protein product displays desirable flavor and functional properties, and its isoflavone content is substantially increased compared to traditional soy protein concentrates and isolates. In addition the total sulfur containing amino acid content is improved compared to soy protein isolates. The method for the manufacture of the novel soy protein product results in improved yield and reduced waste products compared to those used to manufacture soy protein concentrates and isolates. The novel soy protein product displays desirable flavor, composition, and performance as an ingredient in the production of dairy or meat based food products such as infant formula, nutritional beverage, milk replacer, soy extended bologna, imitation processed cheese spread, water-injected ham, yogurt and frozen dessert.
Patent CA-2253190-A1 (CA)
Title: Procede et appareil permettant d'incorporer un equipement dans un systeme informatique
Inventor: GHORI AMAR
IPC: H04N5/44
Filed: 1998-01-30
Abstract: L'invention concerne un procédé et un appareil permettant d'incorporer un équipement dans un système informatique. Un mode de réalisation de l'invention prévoit un ordinateur pourvu d'un premier émetteur-récepteur radio numérique de couplage communicant avec le premier émetteur-récepteur radio. Cet équipement comprend également (1) un dispositif de sortie, couplé de façon communicante au second émetteur-récepteur radio de manière à obtenir une présentation de sortie qui soit fonction des signaux provenant de l'ordinateur via les émetteurs-récepteurs radio, et (2) un dispositif d'entrée, couplé de façon communicante au second émetteur-récepteur radio de manière à recevoir les signaux en provenance d'un opérateur de l'équipement.
Patent CA-2258526-A1 (CA)
Title: Tie-2 receptor ligands (tie ligand-3; tie ligand-4) and their uses
Inventor: JONES PAMELA F
IPC: C12N15/12
Filed: 1997-06-19
Abstract: The present invention provides for an isolated nucleic acid molecule encoding a member of the TIE ligand family. The present invention also provides for an isolated nucleic acid molecule encoding TIE ligand-3 or TIE ligand-4. In addition, the invention provides for a receptor body which specifically binds TIE ligand-3 or TIE ligand-4. The invention also provides an antibody which specifically binds TIE ligand-3 or TIE ligand-4. The invention further provides for an antagonist of TIE. The invention also provides for therapeutic compositions as well as a method of blocking blood vessel growth, a method of promoting neovascularization, a method of promoting the growth or differentiation of a cell expressing the TIE receptor, a method of blocking the growth or differentiation of a cell expressing the TIE receptor and a method of attenuating or preventing tumor growth in a human.
Patent CA-2258741-A1 (CA)
Title: A method and an arrangement for closing at least one end of a tube and a plug for said closing
Inventor: ANDERSSON LOA
IPC: B65D59/02
Filed: 1997-05-13
Abstract: The invention relates to a method, an arrangement and a plug (4) separated from a strip for closing at least one end of a tube (8) to protect the tube (8) against internal dirtying. The plug (4) formed for closing a tube end (12) is together with similar formed plugs integrally formed one after the other in a predetermined distance from each other in a longitudinal line in a continuous strip (5) and is provided with a handle formation (18) by which the plug (4) can be taken out from its mounted position in the tube (8) before or in connection with using the tube (8).
Patent CA-2262554-A1 (CA)
Inventor: SCHALLER JOCHEN
IPC: G02F1/1503
Filed: 1997-07-24
Abstract: Electrochromic indicating devices, whose conductive-coated plates are divided into electrically separated segments, which are individually contactable and contain a solvent, specific electrochromic substances and possibly conducting salts between those plates, are characterized by an excellent edge definition and a high contrast.
Patent CA-2265854-A1 (CA)
Inventor: BERGSTRAND HAKAN
IPC: C07D403/04
Filed: 1997-09-19
Abstract: The present invention provides optionally substituted and/or annulated compounds of formula (I) wherein X, Y, Z and A is each independently carbon or nitrogen, and at least two of X, Y, Z and A are carbon; and pharmaceutically acceptable salts thereof with the proviso that: 3-(1H-Indol-3-yl)-1H-quinoxalin-2-one, 3-(2-Methyl-1H-indol-3-yl)-1H-quinoxalin-2-one, and 3-(1,2-Diphenyl-1H-indol-3-yl)-1H-quinoxalin-2-one are excluded from compounds of formula (I). The invention includes the use of compounds of formula (I) in medical therapy, particularly in the therapy of conditions requiring inhibition of protein kinase C.
Patent CA-2269633-A1 (CA)
Title: Candida albicans proteins associated with virulence and hyphal formation and uses thereof
Inventor: THOMAS DAVID Y
IPC: C12N9/16
Filed: 1997-10-29
Abstract: The present invention relates to Candida albicans proteins, such as CaCla4p, Cst20p, CaCdc42p and CaBemlp, associated with virulence and hyphal formation and uses thereof, such as to design screening tests for inhibitors for the treatment of pathogenic fungi infections and/or inflammation conditions. The invention also relates to an in vitro screening test for compounds to inhibit the biological activity of at least one protein selected from the group consisting of CaCla4p, Cst20p, CaCdc42p and CaBemlp, which comprises: a) at least one of said proteins; and b) means to monitor the biological activity of said at least one protein; thereby compounds are tested for their inhibiting potential.
Patent CA-2275491-A1 (CA)
Title: Pathogen-induced plant promoters
Inventor: GHEYSEN GODELIEVE
IPC: C07K14/415
Filed: 1998-01-19
Abstract: New pathogen-induced promoters are provided, particularly nematode-induced promoters, which are characterized by their selective induction of expression in the vicinity of the pathogen infection sites, such as the fixed feeding cells induced by infection of the plant by nematodes. Further provided are chimeric genes comprising these promoters as regulatory elements, as well as transgenic plants, comprising those chimeric genes, which are less susceptible to pathogen infections.
Patent CA-2277300-A1 (CA)
Inventor: MAY TIMOTHY J
IPC: B31B19/90
Filed: 1997-12-05
Abstract: A flexible bag (10) includes a female profile (32) and a male profile (34) cooperatively arranged to inhibit interlock-blockage caused by small substances. The female profile includes first (40)and second (42) opposing legs. Each of the legs of the female profile includes a securing head (44, 46) at an extended end, a base (48) adapted for attachment to the first panel section of the bag. A neck (49) is between the securing head and the base. At least one of the first and second legs has a plurality of portions removed to form a first series of breaks (52). The portions removed include the securing head and the neck. The male profile is adapted for attachment to the second panel section of the bag, and is arranged to interlock with the first and second legs. A method of constructing a flexible bag, and a method for using a flexible bag are also described.
Patent CA-2277418-A1 (CA)
Title: High voltage direct current electrical cable with mass-impregnated insulation
Inventor: BOSISIO CLAUDIO
IPC: H01B17/34
Filed: 1999-07-06
Abstract: Mass-impregnated electrical cable, particularly for carrying high voltage direct current, having an insulation in which, around the insulating layer impregnated with an insulating fluid, a containing layer is provided comprising at least one winding of a tape of a semiconducting elastomeric material, which exerts an effective action of containing the insulating fluid, while preventing formation of micro-cavities within the impregnated insulating layer. The material constituting the tape has high physical--chemical resistance to the degrading action of the components of the insulating fluid, both in the cold state, and, in particular, at the operating temperature of the cable.
Patent CA-2278609-A1 (CA)
Title: Remote data gateway
Inventor: CHANEY CHRISTINE S
IPC: H04L29/06
Filed: 1998-02-06
Abstract: A system and method for permitting a customer to perform intelligent call routing (ICR) in a carrier's network. A Remote Data Gateway (RDG) (210) permits customers to control the routing of their call traffic on the carrier's network. The RDG (210) provides the routing and delivery of call processing queries, generated on the carrier's network, to a Customer Access Point (CAP) (212, 306). The customer can use the CAP (212) to perform ICR and other call processing functions. The results are sent as a response back to the RDG (210, 308), which delivers the response to the carrier's network for implementation (312). Features provided by the RDG (210) include improved security, improved service reliability, message and protocol translation, and maximum efficiency of network and system resources through a dynamic registration process.
Patent CA-2278898-A1 (CA)
Title: Process and continuously operating press for the manufacture of endless veneer laminates
Inventor: BIELFELDT FRIEDRICH B
IPC: B27D/
Filed: 1999-07-27
Abstract: The invention concerns a process and a continuously operating press for manufacture of endless veneer laminates from a veneer panel strand assembled from several layers one over the other and one behind the other by means of gluing and pressing. The invention consists in that an application of convexly contacting compressive force is administered from above and below to the veneer panel strand from the longitudinal centre line A-A to both longitudinal sides in an air extraction intake wedge (B), whereby from the beginning of the air extraction intake wedge (I) to the end of the air extraction intake wedge (II) the convex application of compressive force steadily becomes a planar application of compressive force, and compression increases.      For this purpose the continuously operating press is provided with an air extraction intake wedge (B) in the intake area of the continuously operating press (5), in which the upper and lower intake compression/heating plates (3' and 4') are convexly curved against the entering veneer panel strand (2) and the convex curvature of the intake compression/heating plates (3' and 4') from the beginning (I) to the end (II) of the air extraction intake wedge (B) can be controlled in plane in accordance with a predetermined compressive force profile through the action of an array of cylinder pistons (12).
Patent CA-2279467-A1 (CA)
Inventor: LAMOUREUX PHILIP
IPC: H04W24/08
Filed: 1999-07-30
Abstract: Method for automatically determining whether a communication trunk is operating properly without having to take the trunk out of service and without the need of a craftsperson to initiate the testing of the communication trunk. The communication trunk is tested for continuity and integrity on a periodic or aperiodic basis.
Patent CA-2281582-A1 (CA)
Title: Antimicrobial agent
Inventor: BROEDEL SHELDON E
IPC: A61P31/04
Filed: 1997-03-28
Abstract: The invention provides a method of treating a fungal infection comprising administering to an animal having a fungal infection a composition comprising an infection treating effective amount of a compound of formula (I), wherein said compound is as above or a pharmaceutically acceptable salt of (I). The invention further provides such compounds and related methods.
Patent CA-2281605-A1 (CA)
Inventor: BLATTER KARSTEN
IPC: C08J3/16
Filed: 1998-02-11
Abstract: The invention concerns homogeneously tinted polyester particles of an average size < 50 .mu.m, having a monomodal granulometric distribution per particle (=d90-d10/d50)2,5. At temperatures < 200 ~C, these particles can be molten to form a continuous coating. The invention also relates to the process of production of same and their use as powder lacquers. In the preferred embodiment, the particles contain units of formulae (1) -CO-X-CO and (2) -O-D-O-, in which X represents a substituted or non-substituted aromatic residue C6 to C14 or an alkylene, polymethylene, cycloalkane or dimethylene-cycloalkane group or an alkandiyle group in a straight or branched chain, possibly unsaturated, and D represents an alkylene, polymethylene, dimethylenecycloalkane group or an alcandiyle group in a straight or branched chain, possibly unsaturated.
Patent CA-2283344-A1 (CA)
Inventor: HERRERA BUCH ANTONIETA
IPC: A61K39/295
Filed: 1998-03-05
Abstract: The present invention relates to the medical field, particularly to the use of new formulations of adjuvants as vaccinal antigenes. The technical objective of the present invention is precisely the development of formulations capable of raising and/or modulating the immune response of the organism to vaccinal antigenes at serum and mucus levels. In order to attain such objective, a formulation has been developed which contains as fundamental components the surface antigene of the B hepatitis virus and the acemanane in adequate proportions. As an extension of such result, formulations have been developed wherein: a) HBsAg is used as carrier of homologous and heterologous antigenes; b) systems for transmitting particulate antigens and c) soluble antigens, in combination with the acemanane in specific proportions. The formulations of this invention are applicable to the pharmaceutical industry as vaccinal formulations both for human and veterinary use.
Patent CA-2284096-A1 (CA)
Title: Anti-microbial coatings having indicator properties and wound dressings
Inventor: PRECHT RODERICK JOHN
IPC: A61L17/00
Filed: 1998-02-17
Abstract: Multilayer anti-microbial materials formed to produce an interference colour, and thus an indicator of anti-microbial effect, are provided. The materials include a partly reflective base layer and a partly reflective, partly transmissive top layer balanced to produce an interference colour. The top layer is formed from an anti-microbial metal with atomic disorder. Dissolution or a change in composition of the top layer on contacting an alcohol or electrolyte causes a change in optical path length so as to produce a change in the interference colour of the material. Multilayer, laminated wound dressings are also provided. The dressing includes a first and second layer, and preferably a third layer. The first and third layers are formed of perforated, non-adherent materials and most preferably carry an anti-microbial coating as above. The second layer is sandwiched between the first and third layers and is formed of an absorbent material. At least one of the layers is formed from a plastic material. The layers are laminated together by ultrasonic welds spaced intermittently on the dressing to allow the dressing to be cut to size with delaminating.
Patent CA-2285627-A1 (CA)
Inventor: ZACKRISSON OLOF MIKAEL
IPC: H01L21/762
Filed: 1998-03-23
Abstract: Method for improving the topography over trench structures in which the provision of extra poly-semiconductor material e.g. polysilicon 20 or nitrate or oxide in the regions of the trench edges and, if necessary, the subsequent oxidation of the extra material prevents the occurrence of regions of high mechanical stress.
Patent CA-2289084-A1 (CA)
Title: Linepipe and structural steel produced by high speed continuous casting
Inventor: GRAY JOHN MALCOLM
IPC: C22C38/04
Filed: 1998-05-15
Abstract: A high strength, high toughness, low carbon/low manganese steel is provided that is further resistant to stepwise cracking and sulfide stress cracking. The steel can be produced by conventional or thin slab casting techniques using normal speeds, with low manganese segregation levels. The steels are excellent candidates for linepipe applications in severe sour gas service.
Patent CA-2294507-A1 (CA)
Inventor: GUTIERREZ ALBERTO JR
IPC: H04J11/00
Filed: 1998-07-17
Abstract: A CDMA communication system supports underlay transmissions and direct spread overlay transmissions such that the overlay transmissions are at least partially orthogonal to underlay transmissions. A base station supports both the underlay transmissions and the overlay transmissions and includes an interface to a mobile switching center, an underlay unit (206), an overlay unit (204) and at least one radio frequency (RF) unit (212). The interface receives communications intended for a plurality of mobile stations serviced by the base station. These communications include underlay communications intended for mobile stations (MSs) supporting underlay transmissions and overlay communications intended for MSs supporting overlay transmissions. The underlay unit (206) receives the underlay portion of the communications and produces underlay transmissions. The overlay unit (204) receives the overlay portion of the communications and produces overlay transmissions. Then, the underlay transmissions and the overlay transmissions are received by the at least one RF unit and transmitted via at least one antenna (214) to the plurality of MSs. Each of the MSs receives both the underlay transmissions and the overlay transmissions.
Patent CA-2294680-A1 (CA)
Title: Refueling cap assembly
Inventor: GRUBER HERBERT
IPC: E05B65/12
Filed: 2000-01-06
Abstract: A refueling cap assembly for opening and closing a filler neck of a fuel tank has a frame which is mounted to the filler neck of the fuel tank. A cover is pivotally mounted to the frame to move between open and closed positions for opening and closing the filler neck. A locking mechanism, having a locking body, is mounted to the frame for securing the cover to the filler neck in the closed position. The locking body moves between a locked position engaging a finger projecting from the cover to secure the cover to the filler neck, and a release position releasing the cover from the filler neck.  The cap assembly is characterized by the locking body moveable in a flip flop manner and having a first abutment to retain the locking body in the locked position when the cover is in the closed position, and a second abutment to retain the locking body in the released position when the cover is in the open position. The locking body flip flops between the locked and released positions upon repeated engagement of the cover with the locking mechanism.     tgBmaX  23
Patent CA-2295488-A1 (CA)
Inventor: GROVES JAMES D
IPC: C08G18/79
Filed: 1997-11-13
Abstract: L'invention concerne une composition pour primaire, qui comprend un composé aliphatique contenant un isocyanate, un polymère hydrocarboné non halogéné comportant des groupes fonctionnels organiques, un polymère hydrocarboné halogéné comportant éventuellement des groupes fonctionnels organiques, et un solvant organique.