baber/WOPTO huggingface dataset:
Patent FI-955661-A0 (FI)
Inventor: BUZZETTI FRANCO
IPC: A61K31/275
Filed: 1995-11-24
Abstract: PCT No. PCT/EP95/00758 Sec. 371 Date Nov. 21, 1995 Sec. 102(e) Date Nov. 21, 1995 PCT Filed Mar. 2, 1995 PCT Pub. No. WO95/26341 PCT Pub. Date Oct. 5, 1995The present invention relates to new compounds of formula    <IMAGE>  (I)  wherein A is a bicyclic ring chosen from naphthalene, tetrahydronaphthalene, quinoline, isoquinoline and indole. B is a R2 substituted benzene ring or an unsubstituted pyridine or thiophene ring; R is hydrogen, C1-C6 alkyl, halogen, nitro, cyano, carboxy or a group NR3R4 wherein each of R3 and R4 is independently hydrogen or C1-C6 alkyl; R1 is hydrogen, C1-C6 alkyl or C1-C6 alkanoyl; R2 is hydrogen, C1-C6 alkyl, halogen, nitro, cyano, carboxy, hydroxy, C1-C6 alkoxy, C1-C6 alkanoyloxy or a group NR3R4 wherein R3 and R4 are as defined above; n is zero or an integer of 1 to 2; x is zero or an integer of 1 to 5; and the pharmaceutically acceptable salts thereof. The compounds of the invention are useful as tyrosine kinase inhibitors.
Patent FI-960274-A0 (FI)
Inventor: WEINBERGER ERIC PATTON
IPC: D04H1/42
Filed: 1996-01-19
Abstract: The present invention relates to absorbent articles such as sanitary napkins, panty liners, and incontinence pads. More particularly, the present invention relates to absorbent articles, such as sanitary napkins, that have undergarment covering components (or "side wrapping elements") that automatically wrap the sides of a wearer's panties and provide an alternative to conventional side flaps. The side wrapping elements have at least one zone of extensibility and at a region therein that is stiffer than the zone of extensibility.
Patent FI-963359-A0 (FI)
Inventor: LEHTINEN EERO
IPC: B60S3/04
Filed: 1996-08-28
Abstract: The invention relates to a method and an apparatus for washing vehicles (6). According to the invention, wax (14) is sprayed to the surface of a vehicle during high-pressure washing of the vehicle. This improves the drying result, and allows the wax to be applied efficiently to the vehicle surface. The washing operation is simple and rapid. <IMAGE>
Patent FI-973410-A0 (FI)
Inventor: HUIJS MATHIJS
IPC: D06M15/41
Filed: 1997-08-20
Abstract: PCT No. PCT/EP96/00718 Sec. 371 Date Nov. 14, 1997 Sec. 102(e) Date Nov. 14, 1997 PCT Filed Feb. 20, 1996 PCT Pub. No. WO96/26164 PCT Pub. Date Aug. 29, 1996The invention relates to a method for manufacturing a product on a basis of mineral wool, including the steps of: i) preparing a phenol-formaldehyde resin, ammonia and a sugar preparation containing aqueous preparation; ii) applying the preparation to the mineral wool; and iii) curing the mineral wool with forming of the product, and to a kit for preparing the mineral wool product, including a container holding the resin preparation and a container holding the sugar preparation.
Patent FI-973451-A0 (FI)
Inventor: ANDELL OVE
IPC: C07F7/28
Filed: 1997-08-22
Abstract: The invention relates to an organometallic compound comprising a central transition metal atom and a ligand coordinated thereto having a heteroatomic ring structure, characterized in that the ligand includes at least three nitrogen atoms, three of them being bonded to the same carbon atom.
Patent FI-982733-A0 (FI)
Inventor: AF URSIN KAIJA
IPC: A61K47/10
Filed: 1998-12-17
Abstract: Aqueous compositions of nonsteroidal triphenylethylene antiestrogens for pharmaceutical use comprising as a solubility enhancing agent a pharmaceutically acceptable mono- or dicarboxylic acid having 1-5 carbon atoms, wherein the carbon chain may further contain 1-4 hydroxyl, 1-3 oxo, or one or several halogen substituents, or a corresponding anion thereof, or methanesulfonic acid or its corresponding anion, in molar excess with respect to the triphenylethylene antiestrogen, optionally together with an organic water miscible co-solvent such as polyethylene glycol (PEG), propylene glycol, ethanol or isopropanol.
Patent IL-67273-A0 (IL)
Title: Alkylcycloalkyl triazolylmethyl ketones and their preparation
IPC: C07C45/51
Filed: 1982-11-16
Abstract: 1. Alkylcycloalkyl triazolylmethyl ketones of the formula   see diagramm : EP0081675,P8,F5   in which R represents straight-chain or branched alkyl with 1 to 6 carbon atoms and n represents the numbers 3, 4, 5, 6 and 7.
Patent IL-76186-A0 (IL)
Title: Solid phase receptor assay for antibiotics of the vancomycin class
IPC: G01N33/94
Filed: 1985-08-26
Abstract: The present invention relates to a method for determining an antibiotic substance capable of binding to a D-Alanyl-D-Alanine dipeptide such as the glycopeptidic antibiotics of the vancomycin class and their derivatives and aglycones. Further objects of the present invention are compositions of matter (kits) and means for exploiting the method of the invention.
Patent IL-80620-A0 (IL)
Title: Stable soluble 1,2-diaminocyclohexane platinum complexes and pharmaceutical compositions containing the same
IPC: A61P35/00
Filed: 1986-11-12
Abstract: Platinum complexes of the formulawherein Z is -CO- or a single bond and R is -COOH or -SO<sub>3</sub>H, and the pharmaceutically acceptable salts thereof with bases, are stable readily water-soluble pharmaceutically active compounds having antitumor, anti-inflammatory and trypanocidal activities.
Patent IL-86722-A0 (IL)
Title: Guanidine-related compounds comprising a tetraphenylborate ion,their preparation and their use
IPC: C07K5/068
Filed: 1988-06-13
Abstract: The compounds comprising a tetraphenylborate ion and a guanidine functional group correspond to the general formula: 
<IMAGE>
 in which R denotes an organic radical containing at least one other amine functional group. 
<??>These compounds are employed as chemical synthesis intermediates, especially in the synthesis of peptides.
Patent IL-86835-A0 (IL)
Title: Functionalized polyamine chelants and rhodium complexes thereof and process for their preparation
IPC: A61K51/10
Filed: 1988-06-22
Abstract: A group of functionalized polyamine chelants that form complexes with rhodium are disclosed. The rhodium complexes can be attached to an antibody or antibody fragment and used for therapeutic or diagnostic purposes.
Patent IL-86929-A0 (IL)
Title: Process for the preparation of 2-aryloxypropionic acids
IPC: C07D213/64
Filed: 1988-06-30
Abstract: A process is provided for the enrichment in R isomer of an aryloxypropionic acid ester and for the stereoselective hydrolysis of an aryloxypropionic acid ester to form the corresponding aryloxypropionic acid in predominantly S configuration which comprises subjecting an aryloxypropionic acid ester of formula I <CHEM> wherein A is an ester residue and preferably an alkyl group, optionally substituted or branched, wherein R min  is an optionally substituted aryl or heterocyclic ring system, containing in addition to carbon atoms one or more atoms selected from nitrogen, sulphur and oxygen, this ring system being optionally substituted and wherein B and D are for example a hydrogen or a halogen atom, to the action of a microorganism or substance derived thereof capable of stereoselective hydrolysis of the COOA group to form the corresponding carboxylic acid predominantly is S configuration.
Patent IL-87825-A0 (IL)
Title: Ortho-substituted benzyl carboxylates and their use as fungicides
IPC: A01N37/02
Filed: 1988-09-20
Abstract: Ortho-substituted benzyl carboxylates of the formula   <IMAGE> I where R1 is alkoxy, alkylthio, halogen or amino, R2 is alkoxycarbonyl, cyano or CONH2, R3 l is hydrogen, halogen, cyano, aryl, aryloxy, a saturated or unsaturated heterocyclic radical, cycloalkyl, or substituted cyclopropyl, X is alkylene, and n is 0 or 1, and fungicides containing these compounds.
Patent IL-98891-A0 (IL)
Title: Production of acetaminophen
IPC: C07C233/25
Filed: 1991-07-18
Abstract: N-acetyl-para-aminophenol is prepared by contacting 4-hydroxyacetophenone oxime with a Beckmann rearrangement catalyst in an alkyl alkanoate reaction solvent. An integrated process is disclosed wherein 4-hydroxyacetophenone is reacted with a hydroxylamine salt and a base to obtain 4-hydroxyacetophenone oxime, the oxime product is extracted from the resulting reaction mixture with a substantially water-immiscible solvent, and the mixture of oxime and substantially water-immiscible solvent is contacted with a Beckmann rearrangement catalyst to produce N-acetyl-para-aminophenol. Novel Beckmann rearrangement catalysts are used to limit by-product formation in the ester solvent.
Patent AU-PQ878600-A0 (AU)
Title: Compositions and methods for the treatment of intact skin
IPC: A61K8/46
Filed: 2000-07-13
Abstract: This invention relates to a method for treating skin damage, comprising the step of administration of a pharmaceutical or dermatological composition of basic milk factors to the area of the skin of a subject in need of such treatment. The invention further relates to a method for cosmetically treating the aged appearance of skin. The skin damage may be the result of normal biological ageing, environmental factors, dermatological disorders, medical treatments, surgical treatments and/or medical conditions. The aged appearance of skin may be attributed to wrinkles, blemishes, sagging, hyperpigmentation, changes to skin thickness and/or a rough appearance. In a preferred embodiment, the subject in need of such treatment requires the enhancement of the youthful appearance of their skin. The invention further relates to compositions for the treated of these conditions.
Patent AU-PR774201-A0 (AU)
Title: High solids module
IPC: B01D63/02
Filed: 2001-09-18
Abstract: A method of cleaning a membrane filtration module is disclosed. The module comprises at least one or more longitudinally extending membranes located in a feed-containing vessel. The membranes have a permeable wall which is subjected to a filtration operation wherein feed containing contaminant matter is applied to one side of the membrane wall and filtrate is withdrawn from the other side of the membrane wall. The method comprises the steps of suspending the filtration operation; performing a cleaning process on the membrane wall to dislodge contaminant matter from the membrane wall into liquid surrounding the membrane: performing a sweep of the feed-containing vessel substantially parallel to the longitudinally extending membranes to remove the liquid containing the dislodged contaminant matter, at least in part, through an opening in a header or other part of the module, and then recommencing the filtration operation.
Patent FI-20015011-A0 (FI)
Inventor: LAHTI AAPO
IPC: H04W8/26
Filed: 2001-06-11
Abstract: The present invention relates to a system comprising a subscriber register (HLR) and subscriber stations (MS, MS') having SIM cards. To make the opening of a new subscription easier than before, the system further comprises activation means (4) arranged to receive from the subscriber an activation message containing at least the identifier of the SIM card associated with the new subscription and credit rating information, and in response to the activation message, the activation means check the credit rating, and if the credit rating is acceptable, the activation means store into the subscriber register (HLR) information that enables the use of the new subscription. <IMAGE>
Patent IL-103944-A0 (IL)
Title: Piperazine derivatives,their preparation and pharmaceutical compositions containing them
IPC: A61K31/34
Filed: 1992-12-02
Abstract: This invention concerns compounds of formula (I)  in optionally substituted by lower alkyl; Z is a bicyclic oxygen-containing aryl radical (e.g. 2,3-dihydro-1,4-benzodioxin-5-yl); R is hydrogen or lower alkyl; R1 is aryl or aryl(lower)alkyl; R2 is hydrogen or lower alkyl; and R3 is hydrogen, an alkyl group of 1 to 10 carbon atoms, cycloalkyl of 3 to 12 carbon atoms; cycloalkyl(lower)alkyl, aryl or aryl(lower)alkyl or R2 and R3 together with the nitrogen atom to which they are both attached represent a saturated heterocyclic ring which may contain a further hetero atom, and the pharmaceutically acceptable acid addition salts thereof. The compounds are 5-HT1A-antagonists which may be used, for example, in treating anxiety.
Patent IL-107267-A0 (IL)
Title: Tnf inhibitors
IPC: C12N15/13
Filed: 1993-10-12
Abstract: Ligands to Tumor Necrosis Factor receptors (TNF-Rs) which inhibit the effect of TNF but not its binding to the TNF-Rs, and ligands interacting with other receptors of the TNF/NGF family, are provided together with methods of producing them.
Patent IL-113309-A0 (IL)
Title: Imidazopyridine derivatives, their preparation and use
IPC: C07D471/04
Filed: 1995-04-10
Abstract: An imidazopyridine derivative of the formula [I]: <CHEM> wherein R<1> is a lower alkyl group, R<2> is a lower alkanoyl group, and R<3> and R<4> are each lower alkyl groups, or both combine at the end thereof to form an alkylene group having 3 to 6 carbon atoms, and a pharmaceutically acceptable salt thereof, said imidazopyridine derivatives have an excellent angiotensin II antagonistic activity and are useful for the prophylaxis or treatment of hypertension.
Patent IL-129026-A0 (IL)
Title: Sulfonamide interleukin-1beta converting enzyme inhibitors
IPC: C07K5/065
Filed: 1997-10-09
Abstract: The present invention relates to compounds that are inhibitors of interleukin-1beta converting enzyme that have the Formula (I). This invention also relates to a method of treatment of stroke, reperfusion injury, Alzheimer's disease, shigellosis, inflammatory diseases, and septic shock and to a pharmaceutically acceptable composition that contains a compound that is an inhibitor of interleukin-1beta converting enzyme.
Patent IL-134217-A0 (IL)
Title: Method and system for manifesting alarms in a telecommunication network
IPC: H04J3/14
Filed: 2000-01-25
Abstract: A method and a Network Element (NE) for manifesting alarms by forming a so called combined Data Quality Byte (DQB) for a particular SDH/SONET data transmission stream. The DQB indicates status of alarms at a particular location of the telecommunication network, via which the stream is transmitted. The DQB can be formed by arranging a plurality of alarm signals, currently actual for the particular data transmission stream, in a predetermined byte associated with the stream frame. The NE, upon receiving from an upstream network element a data transmission stream with its DQB 1 formed upstream, creates an updated DQB 2 and compares DQB 1 with DQB 2 to manifest an alarm status change DeltaDQB for estimating quality of transmission via the network section.
Patent IL-140691-A0 (IL)
Title: Telephone apparatus with volume control
IPC: H04M1/60
Filed: 1999-07-26
Abstract: The volume of a loudspeaker in a telephone is automatically adjusted according to the ambient noise at the telephone location. During a predetermined time window which exists during the initial period of a telephone call, the ambient noise is measured, and the volume of the loudspeaker adjusted accordingly. For example, the time period may exist between the time when the telephone goes off-hook, until the time when the handset is placed near the ear. Adjusting the ambient noise during this period has the advantage of not having to filter out the user's speech, as would be the case when measuring the ambient noise while the user is speaking. Furthermore, there is no requirement for circuitry which detects gaps in speech.
Patent IL-141422-A0 (IL)
Title: Clip fitting for a hose
IPC: F16L33/02
Filed: 1999-09-09
Abstract: A clip fitting for a hose that includes a hose nipple defining at least one circular groove. A circular seal is positioned in the groove. At least one hose clip is mounted on the hose nipple. At least one clamp is positioned on the hose clip over the seal. The fitting provides an improved seal between the hose and the nipple.
Patent IL-141596-A0 (IL)
Title: Aza-bicycles which modulate the inhibition of cell adhesion
IPC: A61K31/4709
Filed: 1999-08-26
Abstract: The invention is directed to physiologically active compounds of formula (I) wherein R1 represents R3-Z3-, R3-L2-R4-Z3-, R3-L3-Ar1-L4-Z3- or R3-L3-Ar1-L2-R4-Z3-; R2 represents hydrogen, halogen, lower alkyl or lower alkoxy; A1 represents a straight chain C1-3alkylene linkage optionally substituted by one or more groups chosen from alkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, imino, oxo, thioxo, or alkyl substituted by -ZR6, -NY1Y2, -CO2R6 or -C(=O)-NY1Y2; L1 represents a direct bond; an alkenylene, alkylene, alkynylene, cycloalkenylene, cycloalkylene, heteroaryldiyl, heterocycloalkylene or arylene linkage each optionally substituted by (a) an acidic functional group, cyano, oxo, -S(O)mR9, R3, -C(=O)-R3, -C(=O)-OR3, -N(R8)-C(=O)R9, -N(R8)-SO2-R9, -NY4Y5 or -[C(=O)-N(R10)-C(R5)(R11)]p-C(=O)-NY4Y5, or by (b) alkyl substituted by an acidic functional group, or S(O)mR9, -C(=O)-NY4Y5 or -NY4Y5; a -[C(=O)-N(R10)-C(R5)(R11)]p- linkage; a -Z2-R12- linkage; a -C(=O)-CH2<
Patent IL-152942-A0 (IL)
Title: 2-ethyl and-2-ethylidene-19-nor-vitamin d compounds and pharmaceutical compositions containing the same
IPC: A61P19/10
Filed: 2001-05-31
Abstract: Biologically active 19-nor vitamin D analogs substituted at C-2 in the A-ring with an ethylidene or an ethyl group. These compounds have preferential activity on mobilizing calcium from bone and either high or normal intestinal calcium transport activity which allows their in vivo administration for the treatment of metabolic bone diseases where bone loss is a major concern. These compounds are also characterized by high cell differentiation activity.
Patent IL-153259-A0 (IL)
Title: Mobile apparatus for complying with safety regulations
IPC: A61H33/04
Filed: 2001-06-07
Abstract: A mobile safety compliance apparatus comprising a shell with a plurality of open compartments closed by doors, a self-contained water supply system and a waste water collection system. The water supply system provides drinking water, tepid hand washing water, and water for a stowable eyewash hingedly attached to the shell. The waste water collection system collects water from the eyewash and a sink mounted in a recessed area of the shell. Doors are removable and have features to facilitate alternative uses such as a stretcher or a freestanding table. A stowable seat and table are hingedly attached to the shell. The apparatus includes an electrical system with battery backup for powering lights, water heating and refrigeration devices, and electronic communication equipment that may be mounted on the shell. The apparatus includes wheels to facilitate its movement and anchor points to secure it to the ground.
Patent IL-153563-A0 (IL)
Title: Matrix metalloproteinase inhibitors
IPC: A61P1/02
Filed: 2001-07-03
Abstract: A compound of the general formula Iwherein Y is O or S;n is 1, 2, 3 or 4;X represents hydroxamic acid, carboxylic acid, phosphonic acid, acetylthiomethyl group or a mercaptomethyl group;R1 iswherein E, when present represents, a bond or optionally substituted methylene or ethylene;s and t are independently 0, 1, 2 or 3;A and A' independently represent a bond, or a saturated or unsaturated, optionally substituted cyclic or heterocyclic hydrocarbon di- or triradical;Z represents a bond, O, S, C(O), C(O)NR7, NR7C(O) or NR7, wherein R7 is hydrogen, hydroxy, branched or straight, saturated or unsaturated, optionally substituted hydrocarbon radical;R5 represents a bond, alkane or alkene diradical, one or more ether diradicals (R-O-R') or amine diradicals (R-N-R'), wherein R and R' independently represent alkane or alkene diradicals with a C-content from 0 to 3;R6 represents hydrogen, hydroxy, halogen, cyano, nitro, branched or straight, saturated or unsaturated, optionally substituted hydrocarbon radical, unsaturated optionally substituted cyclic or heterocyclic hydrocarbon radical, NR8R9, C(O)NR8R9, C(O)R8, CO(O)R8, S(O)2R9, wherein each R8 and R9 independently represent hydrogen, halogen, a branched or straight, saturated or unsaturated, optionally substituted hydrocarbon radical;R2 represents hydrogen, (C1-8)alkyl, (C2-6)alkenyl, (C3-8)cycloalkyl, aryl(C0-6)alkyl or heteroaryl(C0-6)alkyl;provided that if A, A', Z and R5 are all bonds, and s and t are both 0 (zero), then R6 is different from hydrogen;or a salt, hydrate or solvate thereof.The compounds are valuable for human and veterinary therapy.
Patent IL-153998-A0 (IL)
Title: Method and arrangement in aseptic preparation
IPC: A61J1/00
Filed: 2001-08-09
Abstract: A first aspect of the invention relates to a method for aseptic preparation with an injection syringe. The syringe comprises a container for injection agent and an immovable connection nozzle connected to the container. The method entails charging the container with air. According to the invention air is forced to pass through an air filter arranged on the connection nozzle. This enables the syringe container to be charged with aseptic air in a simple and reliable fashion. Other aspects of the invention relate to devices for performing the method, viz. an injection syringe equipped with an air filter in the connection nozzle, a filter unit ( 2 ) connectable to an injection syringe's ( 1 ) connection nozzle ( 13 ) and a system comprising an injection syringe ( 1 ) and a separate filter unit ( 2 ). The invention devices convey advantages of the same kind as the invention method.
Patent IL-158326-A0 (IL)
Title: Progressive addition lenses
IPC: G02C7/06
Filed: 2002-03-14
Abstract: The present provides progressive addition lens designs and lenses in which unwanted lens astigmatism is reduced as compared to conventional progressive addition lenses. The lenses of the invention containing at least one surface that is a composite of a progressive surface design and a regressive surface design.
Patent IL-175560-A0 (IL)
Title: A device for demarcating an area
Filed: 2006-05-11
Abstract: The invention relates to a device for demarcating an area, in particular for limiting the freedom of movement of animals walking about freely. The device according to the invention is provided with a demarcating element (2) that is connected with a first vehicle (1) and with at least a second vehicle (10), and at least a first vehicle (1) being provided with a tracking arm structure (3) for making it possible to track a guide element (4) disposed in the area, such as for example a wire fencing. The demarcating element (2) is disposed in a stretched position between the two vehicles (1, 10) in such a way that the demarcating element (2) does not exert force on the tracking arm structure (3).
Patent IL-177784-A0 (IL)
Title: Closure system for tubular organs
IPC: B29C45/16
Filed: 2006-08-30
Abstract: Surgically implantable adjustable ring (1) comprising a first (3) and second (4) end parts and which is designed to be closed around a tubular organ towards its two end parts (3,4) by a closure system (2,5) to adjust the diameter of said tubular organ by forming a loop, the first end part (3) forming a sleeve having a first (6) and second (7) open end parts and which is designed to receive the ring second end part (4), the sleeve main axis being defined along a direction which is substantially perpendicular to the main direction of the ring first end part (3), the ring second part (4) furthermore comprising a locking protrusion (2) adapted to hold the sleeve (3) and thereby secure the ring in a closed position, characterized by the fact that the first end part comprises a tab (9) extending from said sleeve second end part and the tab comprises a flexible portion (10,13,14) being more flexible than the remaining part of the tab such as to prevent an accidental opening of the closure system.
Patent IL-179481-A0 (IL)
Title: Minimizing powder retention on surfaces
IPC: A61M15/00
Filed: 2006-11-22
Abstract: The invention relates to a method for enclosing a metered, dry powder medication dose comprising at least one active pharmaceutical ingredient (API) and a metered dose of at least one dry powder excipient in a common space of a dose container. The deposited doses in the common dose container constitute a medical product. The method and the medical product are effective in raising the emitted medication dose output and improving the therapeutic efficacy when the doses are delivered together from a dry powder inhaler.