baber/WOPTO huggingface dataset:
Patent CA-2430181-A1 (CA)
Title: System and method for tracking inventory
Inventor: COVELEY MICHAEL E
IPC: G07G1/00
Filed: 2003-05-27
Abstract: An inventory-tracking unit associated with a storage unit holding items to be dispensed includes a card reader to read an access card issued to a user and a scanner to scan data from items removed from the storage unit. A processor communicates with a sensor in the storage unit and with the card reader and scanner. The sensor provides item data to the processor that is associated with items removed from the storage emit. The processor compares item data received from the sensor with the data received from the scanner to detect coincidence. The processor generates a transaction upon coincidence of item data received from the sensor with the scanned data. A communications interface transmits the transaction to a remote site.
Patent CA-2430767-A1 (CA)
Title: Doppler ultrasound method and apparatus for monitoring blood flow and detecting emboli
Inventor: MYERS TIMOTHY R
IPC: A61B8/08
Filed: 2001-12-06
Abstract: A pulse Doppler ultrasound system and associated methods are described for monitoring blood flow and detecting emboli. A graphical information display includes simultaneously displayed depth-mode (102) and spectrogram (108) displays. The depth-mode display (102) indicates the various positions along the ultrasound beam axis at which blood flow is detected. These positions are indicated as one or more colored regions (104, 106), with the color indicating direction of blood flow and varying in intensity as a function of detected Doppler ultrasound signal amplitude or detected blood flow velocity. The depth-mode display also includes a pointer (109) whose position may be selected by a user. The spectrogram displayed corresponds to the location identified by the pointer (109). Embolus detection is also provided.
Patent CA-2433151-A1 (CA)
Title: Stylus computer
Inventor: GHASSABIAN FIROOZ
IPC: B43K29/00
Filed: 2001-12-26
Abstract: The present invention is directed to a pointing device writing tip comprised of a surface being structured in a manner that while writing with the writing tip on a writing surface (10), the contacts of the writing tip with the writing surface (10) produce different sounds in different directions (14). A  hand writing recognition system is provided based on at least the recognition of sounds produced by the writing tip having a surface being structured in a manner that while writing with the writing tip on the writing surface (10), the contacts of the writing tip with the writing surface (10) produce different sounds in different directions (14) for use by the recognition system.
Patent CA-2435409-A1 (CA)
Title: Novel cannabimimetic ligands
Inventor: DENG HONGFENG
IPC: A61P25/28
Filed: 2002-01-25
Abstract: Disclosed are heterocyclic compounds and methods for their manufacture. The disclosed compounds are surprisingly potent and selective cannabinoids. Also disclosed are methods of using the disclosed compounds, including use of the disclosed compounds to stimulate a cannabinoid receptor, to provide a physiological effect in an animal or individual and to treat a condition in an animal or individual.
Patent CA-2435581-A1 (CA)
Title: Electrical cable with temperature sensing means and method of manufacture
Inventor: SANDERS EUGENE TURNER
IPC: G02B6/44
Filed: 2003-07-18
Abstract: An electrical cable having a holding member arranged longitudinally along the cable for an optic fiber, which can be used for temperature sensing and/or communications. The holding member can replace one or more strands of the cable, be placed inside an interstice of the cable, be placed in between various layers of the cable, or placed in the jacket of the cable. The cable can be produced through the addition of a planetary strander device to a wire assembly apparatus.
Patent CA-2435606-A1 (CA)
Inventor: MUELLER RAINER
IPC: C12N15/55
Filed: 2002-02-05
Abstract: L'invention concerne un procédé permettant d'exprimer de manière soluble un gène codant la protéinase K dans de la levure, par ex. dans la pichia pastoris, puis de le sécréter dans le milieu de culture. L'invention concerne en outre un procédé de purification de la protéinase K exprimée et sécrétée de manière hétérologue.
Patent CA-2437040-A1 (CA)
Inventor: WELLINGS DONALD ALFRED
IPC: C07H21/00
Filed: 2001-12-03
Abstract: L'invention concerne un procédé de synthèse d'oligonucléotides phosphorothioate qui consiste à assembler un complexe aligonucléotide à un support solide en présence d'acétonitrile, avant le clivage de l'oligonucléotide du support solide en retirant l'acétonitrile et en clivant l'oligonucléotide du support solide. Ce procédé est adapté en particulier à la synthèse à grande échelle de nucléotides. On peut retirer l'acétonitrile du support solide par séchage et/ou lavage au moyen de solvants. Les solvants de lavage utilisés de préférence contiendront des trialkylamines.
Patent CA-2437618-A1 (CA)
Title: Urine assay for ovarian reserve
Inventor: BATEMAN PAUL NORTH
IPC: G01N33/543
Filed: 2002-02-14
Abstract: It has been found that a urine test for ovarian reserve can be provided whic h is equivalent in sensitivity to current laboratory methods which determine ovarian reserve based on FSH levels in serum. A lateral flow device for indicating ovarian reserve is disclosed. The device has an application zone for receiving a urine sample, a labelling zone containing label which binds to FSH in the sample, and a detection zone where FSH-bound label is retained. T he detection zone has a threshold value which corresponds to a serum FSH level of between 5-20 mIU/ml (e.g. 10mIU/ml). A test result above the threshold value indicates diminished ovarian reserve.
Patent CA-2438231-A1 (CA)
Inventor: KINNEY GENE G
IPC: A61P25/06
Filed: 2002-02-14
Abstract: Cette invention concerne une méthode de traitement des troubles sensibles à la modulation des canaux KCNQ potassium. Ce traitement consiste dans l'administration, à un mammifère qui en a besoin, d'une dose efficace au plan thérapeutique d'un dérivé de 2,4-disubstitué pyrimidine-5-carboxamide représenté par la formule (I). Dans cette formule, R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ sont tels que définis dans le descriptif. La présente invention concerne également des compositions pharmaceutiques renfermant des ouvreurs ou des activateurs des canaux KCNQ potassium et tout particulièrement le traitement de troubles sensibles à l'activité de canaux KCNQ potassium, tels que la migraine.
Patent CA-2438902-A1 (CA)
Title: Manufacturing process to control particle size
Inventor: SCHRAMM ERNST
IPC: A61K51/00
Filed: 2002-02-27
Abstract: A process for preparing a sterile injectable suspension of radiolabeled macroaggregated serum albumin suitable for use in scanning a mammalian patie nt consisting of: 1) purifying serum albumin with a saline solution; 2) bufferi ng the purified serum albumin; 3) adding stannous halide in HCI solution to the buffered mixture to obtain a reaction mixture; 4) gradually heating and cooling the reaction mixture to form macroaggregate particles; 5) separating the macroaggregates from the reaction mixture; 6) suspending the macroaggregates in sterile water for injection; 7) adding purified serum albumin; 8) lyophilizing the suspension; and 9) reconstituting the radiolabeled lyophilizate with 99 m Tc. The invention also includes a proces s for preparing a stable, sterile lyophilizate of macroaggregate particles of human serum albumin consisting of steps 1-7.
Patent CA-2441700-A1 (CA)
Inventor: WOOD WILLIAM I
IPC: G01N33/15
Filed: 2001-03-22
Abstract: The present invention is directed to Bolekine polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent CA-2442803-A1 (CA)
Title: Structure and method for managing workshares in a parallel region
Inventor: SILVERA RAUL E
IPC: G06F15/76
Filed: 2003-09-26
Abstract: A data processing system is adapted to execute at least one workshare construct in a parallel region. The data processing system uses at least one thread for executing a corresponding subsection of the workshare construct and provides control blocks for managing corresponding workshare constructs in the parallel region. A method of managing the control blocks comprises: adding an array of control blocks to a control block queue;  assigning control blocks in the initialized array to corresponding workshare constructs in the parallel region until a barrier is reached; and waiting at the barrier for all threads in the parallel region to complete their corresponding subsections and then resetting the control block to the beginning of the control block queue. Also provided are a computer program product and a data processing system for implementing the method.
Patent CA-2442878-A1 (CA)
Inventor: LANGLOIS PASCAL
IPC: C07D333/40
Filed: 2003-09-23
Abstract: Procédé de synthèse industriel du ranélate de strontium de formule (I): (voir formula I) et de ses hydrates.
Patent CA-2443586-A1 (CA)
Title: Methods of forming shaped articles from suspensions
Inventor: DUNSTAN DAVID EDWIN
IPC: B29C39/02
Filed: 2001-04-06
Abstract: The invention relates to methods of forming shaped articles from suspensions which include ceramic or metallic powder, or from solutions or suspensions which include one or more pharmaceutical substances or other components. The method comprises the steps of: (a) combining solvent, polymer, cross-linking agent precursor and optional further components and placing into a mould of desired shape; (b) increasing temperature of mould contents to activate cros s- linking agent; (c) allowing mould contents to solidify to sufficient extent to remove mould; (d) removing shaped article from the mould.
Patent CA-2444645-A1 (CA)
Title: Cell culture device
Inventor: YENCHIK RONNIE J
IPC: C12M1/34
Filed: 2003-10-10
Abstract: A culture device for cellular media including a biomedia growth chamber defining a closed environment and an electronically controllable jetting device in communication with a source of material supporting biological function.    The jetting device emits the material into the biomedia growth chamber.
Patent CA-2446838-A1 (CA)
Inventor: WALLACE ROBYN HEATHER
IPC: G01N33/15
Filed: 2002-05-09
Abstract: An isolated nucleic acid molecule encoding a mutant mammalian beta-1 subunit of a voltage-gated sodium channel wherein a mutation event has occurred and said mutation event disrupts the functioning of an assembled sodium channel so as to produce an epilepsy phenotype, with the proviso that said mutation event is not one which results in a C121W substitution in the encoded polypeptide.
Patent CA-2447312-A1 (CA)
Title: Methods and apparatus for rapidly measuring pressure in earth formations
Inventor: RAMAKRISHNAN TERIZHANDUR S
IPC: E21B47/06
Filed: 2003-10-30
Abstract: Methods and apparatus for rapidly measuring pressure in earth formations are disclosed. According to a first embodiment of the apparatus, a probe is provided with a movable piston having a sensor built into the piston. According to a second embodiment of the apparatus, the pressure sensor is mounted adjacent to or within the piston cylinder and a fluid pathway is provided from the sensor to the interior of the cylinder. Methods of operating the first and second embodiments include delivering the probe to a desired location in a borehole, setting the probe against the formation, and withdrawing the piston to draw down fluid for pressure sensing. A third embodiment of the probe is similar to the second but is provided with a spring loaded metal protector surrounding the cylinder and an annular rubber facing. The third embodiment is preferably used in a semi-continuous pressure measuring tool or an LWD tool having a piston controlled bowspring and a piston controlled articulated member carrying the probe. The tool is moved in a semi-set mode and when located at a desired depth is rapidly put in a fully-set mode.
Patent CA-2447697-A1 (CA)
Title: Alteration of embryo/endosperm size during seed development
Inventor: NAGASAWA NOBUHIRO
IPC: C12Q1/68
Filed: 2002-06-04
Abstract: Isolated nucleic acid fragments and recombinant constructs comprising such fragments for altering embryo/endosperm size during seed development are disclosed along with a method of controlling embryo/endosperm size during seed development in plants.
Patent CA-2449941-A1 (CA)
Title: Use of radiopharmaceutical complexes in achieving transplantation tolerance
Inventor: RICORDI CAMILLO
IPC: A61K51/00
Filed: 2002-06-11
Abstract: Non-lethal methods of conditioning a recipient prior to bone marrow transplantation to achieve highly enhanced, stable, long-term hematopoietic chimerism in presence of transient immunosuppression are described. In particular, the administration of non-lethal doses of bone-seeking radiopharmaceuticals such as 153Samarium Lexidronam, a radioactive compound linked to a tetraphosphonate group, to target bone marrow cells, are disclosed herein.
Patent CA-2452442-A1 (CA)
Title: Polyfunctional biocompatible hydrogel and method for the production thereof
Inventor: LOPATIN VLADISLAV VICTOROVICH
IPC: A61K47/32
Filed: 2002-04-10
Abstract: The inventive polyfunctional biocompatible hydrogel comprises 1.95-8.0 mass %  of acrylamide, 0.54-3.0 mass% of methacrylamide, 0.003-0.4 mass% of 2-hydroxyethyl methacrylate, 0.006-0.6 mass% of N,N'-methylen-bis-acrylamide, and water up to 100 mass%. The hydrogel is produced by copolymerising said monomers in an aqueous medium in the presence of a peroxide polymerisation initiator, the incubation of a reaction mixture being carried out in three stages. The first stage is carried out at a temperature ranging from 20 to 30~C during a time of 12 to 24 hours, the second stage is carried out by irradiating with .gamma.-radiation dose of 0.4 to 1.0 megarad, the third stage being carried out at a temperature ranging from 100 to 130~C and a pressure of 0 to 1.2 atm. during a time of 20 to 40 minutes.
Patent CA-2455598-A1 (CA)
Inventor: DECHENE NEAL EDWARD
IPC: A61K33/24
Filed: 2002-07-26
Abstract: Lipid constructs containing a chelator, a targeting entity, a detectable entity, and/or a therapeutic entity are provided, as well as methods relating to their use. The therapeutic or treatment entity may be associated with the lipid construct by covalent or non-covalent means. In some cases, the therapeutic or treatment entity is a radioisotope.
Patent CA-2457751-A1 (CA)
Inventor: DENHAM JONATHAN GEORGE
IPC: C02F1/42
Filed: 2002-06-03
Abstract: A sprayer, which in one embodiment, is a hand held ergonomic sprayer is disclosed herein. The sprayer may include: a housing through which water flows; a handle for gripping by a user, which is joined to the housing; at least one spray nozzle operatively connected to the housing; and, a connection for a hose, the connection being joined to the housing. In one non-limiting embodiment, when the sprayer has one end of a water-filled hose connected thereto, the combination of the sprayer and suspended portion of the hose has a combined center of gravity that passes through the axis of the sprayer handle. The sprayers described herein may also have other features, and provide other benefits that do not require the sprayers to have an ergonomic design.
Patent CA-2458477-A1 (CA)
Title: 3-substituted 6,7-dihydroxytetrahydroisoquinoline derivatives for use as antibacterial agents
Inventor: BURRI KASPAR
IPC: A61K31/4725
Filed: 2002-08-09
Abstract: The invention relates to novel tetrahydroisoquinoline derivatives of general formula I and theirs use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and their use as anti - infectives, wherein R1, R2 and R3 are as defined in claim 1.
Patent CA-2463898-A1 (CA)
Title: Methods and materials for targeting and affecting selected cells
Inventor: FAULK W PAGE
IPC: A61K47/48
Filed: 2002-10-17
Abstract: Diseased tissue is treated by contact with a protein that preferentially bin ds to cells in the diseased tissue, the protein carrying with it a plurality of cell-affecting entities.
Patent CA-2466424-A1 (CA)
Title: Utilisation d'inhibiteurs des rho-kinases pour la stimulation de la croissance nerveuse, pour l'inhibition de la formation de tissus cicatriciels et/ou pour la reduction d'une lesion secondaire
Inventor: MONNIER PHILIPPE P
IPC: A61K31/00
Filed: 2002-10-31
Abstract: La présente invention concerne l'utilisation d'inhibiteurs des Rho-kinases pour la stimulation <i>in vivo</i> de la croissance nerveuse, pour l'inhibition <i>in vivo</i> de la formation de tissus cicatriciels et/ou pour la réduction <i>in vivo</i> d'une lésion secondaire.
Patent CA-2476716-A1 (CA)
Title: Method for the production of a laminate with mutually offset layers
Inventor: RAJABALI ABDOEL FAZIEL
IPC: B32B15/08
Filed: 2004-08-06
Abstract: A method for the production under elevated pressure and temperature of a laminate (1, 1') consisting of a pack with alternating metal layers (2) and plastic bonding layers (3), comprises stacking a first series (8) of layers on top of one another in a mould, then stacking at least a second series (7, 7') of layers on top of the first series (8) of layers, with the formation of the pack of layers such that at at least one edge of the pack at least one (7, 7') of the series is stepped back with respect to the other series (8), an auxiliary tool (12) being placed alongside the stepped-back series (7, 7') and an the other, non-stepped-back series (8) and a gap (13) being formed between the stepped back series (7, 7') and that side (14) of the auxiliary tool (12) facing said series, raising the temperature and the pressure on the pack and the auxiliary (12) tool such that the binder in the plastic bonding layers (3) is made to flow and some of the binder present in the stepped back series (7, 7') collects in said gap (13).
Patent CA-2482267-A1 (CA)
Title: Weight selection methods and apparatus
Inventor: KRULL MARK A
IPC: A63B21/075
Filed: 2003-04-15
Abstract: An exercise dumbbell (100) has at least one weight selector (160) that is rotatable into engagement with various combination of weights (227-229) at opposite ends of the handle (120). On a first embodiment, first and second weight selectors (160) are rotatably mounted on opposite ends of a bar (120) for independent rotation relative to the handle (120). On a second embodimen t, first and second weight selectors (560) are keyed to a common bar (510) and rotated together therewith relative to the handle (510).
Patent CA-2484152-A1 (CA)
Inventor: STEINMANN KURT
IPC: B66B1/20
Filed: 2004-10-07
Abstract: A method of controlling a lift installation, which comprises a lift cage (EC) transporting passengers between storeys (1 to 18) of a building, comprises the following method steps: a) the travel wishes of the passengers are input by way of a destination call control and booked by the destination call control as destination calls and b) an instantaneous load disposed in the lift cage (EC) is determined by a load measuring device at a fixable point in time.   In order to make uniform the waiting times of passengers in the case of incorrect operation of the destination call control and to ensure, for all passengers, an optimised transport time with maximum transport capacity the method additionally proposes that c) the instantaneous load is compared with a full load parameter and in the case of exceeding of the full load parameter a bypass function is activated. The bypass function is in that case activated for those storeys for which destination storeys are booked and which are passed during a half circuit of the lift cage.
Patent CA-2485596-A1 (CA)
Title: Pyrophosphorolysis activated polymerization (pap)
Inventor: LIU QIANG
IPC: C12Q1/68
Filed: 2003-05-09
Abstract: A novel method of pyrophosphorolysis activated polymerization (PAP) has been developed. In PAP, pyrophosphorolysis and polymerization by DNA polymerase are coupled serially for each amplification by using an activatable oligonucleotide P* that has a non-extendible 3'-deoxynucleotide at its 3' terminus. PAP can be applied for exponential amplification or for linear amplification. PAP can be applied to amplification of a rare allele in admixture with one or more wild-type alleles by using an activatable oligonucleotide P* that is an exact match at its 3' end for the rare allele but has a mismatch at or near its 3' terminus for the wild-type allele. PAP is inhibited by a mismatch in the 3' specific sequence as far as 16 nucleotides away from the 3' terminus. PAP can greatly increase the specificity of detection of an extremely rare mutant allele in the presence of the wild-type allele. Specificity results from both pyrophosphorolysis and polymerization since significant nonspecific amplification requires the combination of mismatch pyrophosphorolysis and misincorporation by the DNA polymerase, an extremely rare event. Using genetically engineered DNA polymerases greatly improves the efficiency of PAP.
Patent CA-2486303-A1 (CA)
Inventor: LAN-HARGEST HSUAN-YIN
IPC: C07D303/32
Filed: 2003-05-21
Abstract: L'histone désacetylase est une métallo-enzyme comportant du zinc au niveau de son site actif. Les composés possédant un groupe caractéristique de liaison au zinc, par exemple un groupe alpha-céto-époxyde, tel qu'un groupe alpha-cétothio, peuvent inhiber l'histone désacétylase. L'inhibition de l'histone désacétylase peuvent réprimer l'expression de gènes, notamment l'expression de gènes associés à la suppression de tumeurs. En conséquence, l'inhibition de l'histone désacetylase peut constituer une voie détournée de traitement du cancer, des troubles hématologiques, tels que les hémoglobinopathies, des affections autosomiques dominantes, telles que la maladie d'Aran-Duchenne et la maladie de Huntington, des troubles métaboliques d'origine génétique, tels que la mucoviscidose et la leucodystrophie avec insuffisance surrénale, ou elle peut permettre la stimulation <i>ex vivo</i> de cellules hématopoïétiques.
Patent CA-2488303-A1 (CA)
Inventor: LAMM FOSTER PHILIP
IPC: C10G32/00
Filed: 2004-11-23
Abstract: A fuel system for an energy conversion device includes a deoxygenator system. A signal generator system includes a multiple of transducers located adjacent a fuel channel. The transducers are arranged to generate acoustic flow chaotization and cavitation-induced phase separation which destroys oxygen depleted boundary layers and significantly improving flow mixing, intensifying oxygen supply to the surface of an oxygen-removing membrane of the deoxygenator system.
Patent CA-2489609-A1 (CA)
Title: Spill protector sleeve for coffee holder and the like
Inventor: EID JEAN
IPC: A47G23/02
Filed: 2004-12-07
Abstract: A spill-protector sleeve for use with a conventional disposable coffee cup, said sleeve adapted to fit snugly onto a conventional paper or other disposable cup and comprising an inner surface, an outer surface, and a bottom junction joining the two surfaces, and comprising a bottom sealing component for retention of any liquid contained between the inner and outer surfaces.
Patent CA-2492017-A1 (CA)
Inventor: GRAZIANO MICHAEL P
IPC: C07K14/705
Filed: 2003-07-17
Abstract: The present invention provides rat and mouse NPC1L1 polypeptides and polynucleotides encoding the polypeptides. Also provided are methods for detecting agonists and antagonists of NPC1L1. Inhibitors of NPC1L1 can be used for inhibiting intestinal cholesterol absorption in a subject.