baber/WOPTO huggingface dataset:
Patent EP-0708098-B1 (EP)
Inventor: YANAGISAWA HIROAKI
IPC: C07D271/07
Filed: 1995-10-09
Granted: 1999-03-03
Abstract: Compounds of formula (I) : <CHEM> in which: R<1> is hydrogen or alkyl; R<2> is alkylene; R<3> is hydrogen, alkyl, alkoxy, alkylthio, halogen, nitro group, amino group, monoalkylamino, dialkylamino, aryl, or aralkyl; X is aryl, or aromatic heterocyclic; Y is oxygen, sulfur or a group of formula >N-R<4>, in which R<4> is hydrogen, alkyl or acyl; and Z is a group of formula (Za), (Zb), (Zc) or (Zd) : <CHEM>   <CHEM> and salts thereof can be used to treat or prevent are included those arising from hyperlipidemia, hyperglycemia, obesity, impaired glucose tolerance (IGT), insulin resistant non-IGT (NGT), non-diagnostic glucose tolerance, insulin resistance, diabetic complications, fatty liver, polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM); in addition the compounds of the present invention have aldose reductase inhibitory activity.
Patent EP-0737192-B1 (EP)
Inventor: BAKER RAYMOND
IPC: A61P25/06
Filed: 1994-12-23
Granted: 2001-10-31
Abstract: The present invention relates to compounds of the formula (I): <CHEM> wherein R<1> is hydrogen, halogen, C1-6alkyl, C1-6alkoxy, CF3, NO2, CN, SR<a>, SOR<a>, SO2R<a>, CO2R<a>, CONR<a>R<b>, C2-6alkenyl, C2-6alkynyl or C1-4alkyl substituted by C1-4alkoxy, where R<a> and R<b> are hydrogen or C1-4alkyl; R<2> is hydrogen, halogen, C1-6alkyl, C1-6alkoxy substituted by C1-4alkoxy or CF3; R<3> is hydrogen, halogen or CF3; R<4> is selected from the definitions of R<1>; R<5> is selected from the definitions of R<2>; R<6> is a 5-membered or 6-membered heterocyclic ring containing 2 or 3 nitrogen atoms optionally substituted by =O or =S and optionally substituted by an aminoalkyl group; R<9a> and R<9b> are hydrogen or C1-4alkyl, or R<9a> and R<9b> are joined to form a C5-7 ring; X is C1-4alkylene optionally substituted by oxo; and Y is a C1-4alkyl group substituted by hydroxyl; and pharmaceutically acceptable salts and prodrugs thereof. <??>The compounds are of particular use in the treatment of pain, inflammation, migraine and emesis.
Patent EP-0746599-B1 (EP)
Inventor: KOTTWITZ BEATRIX
IPC: C11D17/06
Filed: 1995-02-13
Granted: 2000-05-24
Abstract: PCT No. PCT/EP95/00506 Sec. 371 Date Aug. 22, 1996 Sec. 102(e) Date Aug. 22, 1996 PCT Filed Feb. 13, 1995 PCT Pub. No. WO95/22592 PCT Pub. Date Aug. 24, 1995A detergent composition containing surfactants selected from anionic, cationic, nonionic, amphoteric and zwitterionic surfactants and a builder component containing 40% to 80% by weight of amorphous alkali metal silicates and 10% to 40% by weight of alkali metal carbonates in the form of a compound, with the proviso that the alkali metal carbonate content is always greater than the alkali metal silicate content, and at most 25% by weight of water, and wherein the compound does not have a homogeneous surface nor a uniform particle size distribution.
Patent EP-0711669-B1 (EP)
Inventor: TANIGUCHI HIDEO
IPC: B41J2/335
Filed: 1995-05-29
Granted: 1998-08-12
Abstract: La tête d'impression thermique présentée comprend un substrat isolant (8) pourvu qu'une phase frontale (8a), d'une phase dorsale (8b), d'une première arête longitudinale (8c) et d'une seconde arête longitudinale (8d). Sur la phase frontale (8a) de ce substrat (8) sont formés une série de points générateurs de chaleur (10a), le long de la première arête longitudinale (8c), un réseau d'électrodes commun (11) conçu pour être connecté électriquement à la série de points générateurs de chaleur (10), à proximité de la première arête longitudinale (8c), et des électrodes individuelles (12) s'étendant dans un sens tel qu'elles sont séparées du réseau d'électrodes commun (11) et adaptées pour être connectées électriquement chacune à son point générateur de chaleur respectif (10a). Les points générateurs de chaleur (10a) sont activés sélectivement par un élément d'excitation, pour générer de la chaleur. Le réseau d'électrodes commun (11) est connecté électriquement à une couche électrode auxilaire (14) qui couvre au moins la première arête longitudinale (8c), la phase dorsale (8b) et la seconde arête longitudinale (8d) du substrat (8).
Patent EP-0771228-B1 (EP)
Inventor: HALDEMANN GASTON
IPC: A63C10/10
Filed: 1995-06-19
Granted: 1998-09-02
Abstract: PCT No. PCT/IB95/00493 Sec. 371 Date Jan. 16, 1997 Sec. 102(e) Date Jan. 16, 1997 PCT Filed Jun. 19, 1995 PCT Pub. No. WO96/03185 PCT Pub. Date Feb. 8, 1996The device for fastening safely a shoe onto a snow board according to the invention includes two lateral jaws (2) carried by arms (15) mounted pivotally at their free ends on a first journal (17) perpendicularly to the plane of the board and movable in a direction parallel to this plane by the action of a resilient member (4) between a closed operative position, in which these jaws cooperate with a profiled pattern of the sole of the shoe and an open position, in which the same is released. Each jaw (2) is connected mechanically to the resilient urging member (4) via a rocking member (6) mounted in such a manner that it exhibits two stable positions, corresponding respectively to the open and to the closed position of the jaws (2).
Patent EP-0802985-B1 (EP)
Inventor: MUELLER ROLF
IPC: C07K14/475
Filed: 1995-08-23
Granted: 2002-12-11
Abstract: PCT No. PCT/EP95/03370 Sec. 371 Date Apr. 18, 1997 Sec. 102(e) Date Apr. 18, 1997 PCT Filed Aug. 25, 1995 PCT Pub. No. WO96/06940 PCT Pub. Date Mar. 7, 1996A DNA sequence for the gene therapy of tumors is described. In its essential elements, the DNA sequence is composed of an activator sequence, a promoter module and a gene for the active substance. The activator sequence is activated, in a cell-specific manner, in proliferating endothelial cells or in cells which are adjacent to these endothelial cells. This activation is regulated by the promoter module in a cell cycle-specific manner. The active substance is an inhibitor of angiogenesis or a cytostatic or cytotoxic molecule. The DNA sequence is inserted into a viral or non-viral vector which is supplemented with a ligand which possesses affinity for the activated endothelial cell.
Patent EP-0790990-B1 (EP)
Inventor: BARNICKI SCOTT DONALD
IPC: C07D311/72
Filed: 1995-11-07
Granted: 2001-06-20
Abstract: L'invention se rapporte à un procédé amélioré de préparation de concentrés de tocophérols et de tocophérols/tocotriénols à partir de distillats d'huiles végétales. On obtient des concentrés de tocophérols renfermant 20 à 80 % en poids de tocophérols, la récupération globale de tocophérols étant comprise entre 72 % et 97 %. Le procédé comporte d'abord une réaction d'estérification au cours de laquelle les alcools plus volatils sont transformés en esters d'acide gras moins volatils, qui est suivie d'une série d'étapes de distillation où les composants à point d'ébullition supérieur et inférieur à celui des tocophérols sont séparés des tocophérols et autres substances à point d'ébullition identique. Les avantages de ce procédé sont que les concentrés de tocophérols et de tocophérols/tocotriénols sont obtenus de manière efficace et économique en un minimum d'étapes, sans utilisation de solvants et avec un investissement relativement réduit.
Patent EP-0793775-B1 (EP)
Inventor: DUNGNER STEFAN
IPC: F02M25/07
Filed: 1995-12-06
Granted: 2001-04-04
Abstract: Dans des moteurs suralimentés, il est difficile de faire recirculer des gaz d'échappement depuis le côté échappement vers le côté admission pendant des conditions de fonctionnement dans lesquelles la pression est plus importante côté admission que côté échappement. Afin d'apporter une solution à ce problème, on incorpore une turbine de recirculation de gaz d'échappement (EGR) (6) dans le flux de gaz d'échappement en série après la turbine (4) du surcompresseur, la turbine EGR étant, de ce fait, actionnée par les gaz d'échappement qui ont déjà traversé la turbine du surcompresseur. On utilise la turbine EGR (6) pour actionner un compresseur de recirculation de gaz d'échappement (EGR) (7) qui produit le flux partiel de gaz devant recirculer vers le collecteur d'admission (2) du moteur à combustion. Ce flux partiel de gaz est dévié du collecteur d'admission (3, 3') et est mis sous pression dans l'étage du compresseur (7). La turbine EGR (6) peut être régulée par une soupape de régulation des gaz d'échappement (15).
Patent EP-0801864-B1 (EP)
Inventor: STEVENS JOHN HERBERT
IPC: H04N5/232
Filed: 1995-12-08
Granted: 2004-06-09
Abstract: Une caméra d'enregistrement vidéo (1000) a une pluralité de modes de fonctionnement et comprend un élément de prise de vues (205, 200) qui reçoit une image et génère des signaux vidéo (Iv) représentatifs de l'image. Un élément d'enregistrement (500) est couplé à l'élément de prise de vues pour enregistrer les signaux vidéo (Iv) représentatifs de l'image. L'élément de prise de vues (205, 200) et l'élément d'enregistrement (500) peuvent être alimentés indépendamment en énergie, ce qui permet de mettre en oeuvre une pluralité de modes de fonctionnement dans lesquels l'élément de prise de vues (205, 200) et l'élément d'enregistrement (500) peuvent être alimentés en énergie en même temps ou non. Un microprocesseur (4000) est couplé de manière réglable à l'élément de prise de vues (205, 200) et à l'élément d'enregistrement (500), ce qui permet de commander de manière adaptative la dissipation de puissance en réponse à une interface extérieure de couplage (J1, J2, P1, S1, W1, 21). On peut utiliser des commandes données par l'utilisateur et un dispositif extérieur de couplage pour commander de manière adaptative l'énergie consommée par la caméra d'enregistrement vidéo (1000).
Patent EP-0842289-B1 (EP)
Inventor: TE RIELE HENRICUS PETRUS JOSEP
IPC: C12N15/90
Filed: 1995-07-26
Granted: 2004-10-20
Abstract: A mammalian cell having a mismatch repair-deficient phenotype is provided, where one or both alleles of a gene essential for mismatch repair, such as an Msh gene, are inactivated. Using this cell in a gene knock-out methodology advantageously allows efficient homologous recombination, even when the DNA sequences of the donor and recipient sequences diverge by significantly more than 0.6%.
Patent EP-0800800-B1 (EP)
IPC: A61F2/06
Filed: 1996-08-29
Granted: 1998-07-15
Abstract: The stent comprises a tubular body movable from the compresses state into the expanded one of larger diameter. A large number of apertures (13,14) in the wall of the body allow its expansion. Both in the compressed and the expanded state the apertures extend in the lengthwise directions. The reinforced connecting portions (15) are situated between adjacent apertures in the lengthwise direction. The sections of wall material between the apertures can form enclosing edges for the latter, joined together in the lengthwise direction and elastic to allow stent expansion. In the peripheral direction they can be joined together by the connecting portions.
Patent EP-0773305-B1 (EP)
Inventor: PINNOW KENNETH
IPC: C22C33/02
Filed: 1996-10-15
Granted: 2000-05-31
Abstract: A high vanadium, powder metallurgy cold work tool steel article and method for production. The chromium, vanadium, and carbon plus nitrogen contents of the steel are controlled during production to achieve a desired combination of corrosion resistance and metal to metal wear resistance. <IMAGE>
Patent EP-0825966-B1 (EP)
Inventor: TONDER FLEMMING WEISS
IPC: D04H1/4209
Filed: 1996-05-14
Granted: 2000-02-16
Abstract: PCT No. PCT/EP96/02068 Sec. 371 Date Jan. 23, 1998 Sec. 102(e) Date Jan. 23, 1998 PCT Filed May 14, 1996 PCT Pub. No. WO96/38391 PCT Pub. Date Dec. 5, 1996The invention relates to an arrangement for cleaning a wool chamber in the manufacture of mineral wool. In the manufacture of mineral wool a binder is added to the stream of fibers which is deflected towards the wool chamber and the binder deposits itself in fine droplets in the fibers. The binder-laden fibers which touch against the walls and roof of the wool chamber adhere to them because the binder hardens upon contact with the hot surfaces. Gradually a hard deposit of binder and fibers is formed upon the walls. According to the invention cleaning of the walls is substantially simplified by means of making the walls and/or roof of a double walled construction, perforating the inner walls and applying a reduced pressure in the cavity between the walls holding a detachable lining against the inner walls by means of suction. When the lining has become coated with deposits of binder and fibers to a certain thickness production is halted and the reduced pressure is broken off whereon the detachable lining together with the deposits falls off and a new detachable lining is applied.
Patent EP-0957720-B1 (EP)
Inventor: STIPEK GRANT
IPC: A47C5/12
Filed: 1996-06-07
Granted: 2009-08-05
Abstract: A seat having a frame made of a molded article in which the molded article is a shell-structure is described. Preferably the molded article describes a lattice structure in the form of a space frame. The molded article is preferably scaled and contoured providing significant structural integration and torsional strength.
Patent EP-0832121-B1 (EP)
Inventor: COWGILL CYNTHIA
IPC: C07K14/65
Filed: 1996-06-07
Granted: 2003-10-29
Abstract: Methods for purifying authentic, properly folded IGF polypeptides from yeast transformants are disclosed. The methods include a refolding step and provide for high yields of authentic IGF from a variety of yeast strains.
Patent EP-0828427-B1 (EP)
Inventor: LAURBAK KRISTEN
IPC: A22C9/00
Filed: 1996-05-20
Granted: 2002-09-11
Abstract: PCT No. PCT/DK96/00221 Sec. 371 Date Nov. 13, 1997 Sec. 102(e) Date Nov. 13, 1997 PCT Filed May 20, 1996 PCT Pub. No. WO96/36233 PCT Pub. Date Nov. 21, 1996A massage plant for the processing of chunks of meat includes a container (22) which is rotatable about its longitudinal axis and includes axially or substantially axially extending interior conveyors (16), each made as a hollow profile containing internal channels. Each conveyor is preferably produced by securing a sheet by means of embossments (e.g., temp-plates or vortex plates), in such a manner that a space is generated between the sheet and the hollow profile which has a connection (42,46) for a fluid for regulating the temperature of the load of meat and brine in the container. The axial orientation of the conveyors makes the entire interior of the container easy to survey. The construction of the conveyors is furthermore comparatively simple, and in the event of a leakage, the valuable meat contained in the container is not contaminated by the fluid, since the spilled matter runs within the hollow profile where it is possible to detect any spillage.
Patent EP-0843780-B1 (EP)
Title: Moteurs a combustion interne a quatre temps avec freinage a commande de decompression a deux temps
Inventor: HU HAORAN
IPC: F01L9/11
Filed: 1996-08-02
Granted: 1999-12-22
Abstract: Un moteur à combustion interne (10) comporte des soupapes (30, 60) d'admission et d'échappement des cylindres qui sont actionnées par des cames d'admission et d'échappement (40, 70) par l'intermédiaire de liaisons hydrauliques (54, 84). Celles-ci ont un jeu sélectif qui permet une modification sélective des ouvertures et fermetures des soupapes (30, 60) des cylindres du moteur. Ces modifications peuvent inclure la suppression complète de toute réaction à certains bossages des cames (40, 70). Les liaisons hydrauliques peuvent être reliées entre elles, de telle sorte que certaines ouvertures de soupapes d'admission soient produites par un bossage de came d'échappement, ou que certaines ouvertures de soupapes d'échappement soient produites par un bossage de came d'admission, ou les deux. Les liaisons et les branchements entre elles sont de préférence à commande électronique. Le moteur s'utilise de préférence soit en mode de puissance positive à quatre temps, soit en mode frein-moteur à commande de décompression à deux temps.
Patent EP-0857088-B1 (EP)
Inventor: ABRAMOV VLADIMIR
IPC: B06B3/00
Filed: 1996-10-17
Granted: 1999-07-07
Abstract: PCT No. PCT/EP96/04502 Sec. 371 Date Jan. 21, 1999 Sec. 102(e) Date Jan. 21, 1999 PCT Filed Oct. 17, 1996 PCT Pub. No. WO97/15404 PCT Pub. Date May 1, 1997A device (10) for transferring ultrasonic energy into a liquid or pasty medium, the device consisting of the following functional elements: a) an AC generator (35) designed for frequencies between 1 kHz and 100 kHz, b) a magnetostrictive or piezoelectric transducer (20) controlled by the output voltage of the AC generator to execute high-frequency (longitudinal) mechanical oscillations, c) a cylindrical waveguide (23) which is excited by the transducer to execute longitudinal resonant oscillations and d) a tubular cavity resonator (24) which is acoustically coupled to the waveguide and which converts the longitudinal resonant oscillations into oscillations transverse to its longitudinal axis (26'), the oscillation energy of the resonator being transferred into the medium (11) which is to be exposed to the ultrasonic energy. The cavity resonator (24) is designed so that the resonance condition is fulfilled for both longitudinal and transverse natural oscillations of its case (36).
Patent EP-0858314-B1 (EP)
Inventor: HOLLENBERG DETLEF
IPC: A61K8/73
Filed: 1996-10-28
Granted: 2002-07-17
Abstract: Described are hair-treatment agents containing a non-ionogenic polymer with units of formula (I), in which X is hydrogen, a straight-chain or branched-chain alkyl group with 1 to 22 carbon atoms or an alkenyl group, insaturated one or several times and with 2 to 22 carbon atoms, in combination with at least one other active substance selected from the following: a group (A) comprising the aminoacids, oligopeptides and polypeptides and their derivatives and/or a group (B) comprising the carbohydrates and/or a group (C) comprising panthenol and non-ionogenic and cationic derivatives of panthenol, with the provision that, when the agent does not contain any active substances from group B or C, the active substance from group A is not a hydrolysed protein of collagen or keratin, but is only an aminoacid chosen from glutamic acid, aspartic acid and valine. Such hair-treatment agents have a number of useful properties. Thus undesirable effects of the environment and hair treatments on the hair are reduced and the appearance of the hair improved.
Patent EP-0789096-B1 (EP)
Inventor: LEUCKX DANIEL
IPC: D01F6/06
Filed: 1997-02-05
Granted: 2000-05-03
Abstract: The present invention relates to polypropylene fibers and nonwoven fabrics produced from spunlaid or staple fibers having improved natural bulk. Said polypropylene fibers are made of a blend of sPP and iPP.
Patent EP-0790079-B1 (EP)
Inventor: JAEGER-WALDAU REINOLD DR
IPC: B05B11/00
Filed: 1997-02-08
Granted: 2005-01-05
Abstract: The unit (2,3) incorporates a spring (30) made of plastic or suchlike and at least one of its cross sectional sides is approximately rectilinear. The spring cross section (50) may have at least two rectilinear sides, and may be four-sided. In the axial plane of the spring the spring cross section preferably has a dimension which differs from its dimension in plane at right angles to the spring axis (10).
Patent EP-0816138-B1 (EP)
Inventor: SUZUKI TATSUO
IPC: B60C27/10
Filed: 1997-06-27
Granted: 2002-03-27
Abstract: A fastening device (10a) for a tire slip preventing apparatus comprising a fastening band (20a) in which a non-extensible rope (21a) and a rubber band (25a) are endlessly connected to each other, and a fastening buckle (30a) having a pair of hooks, an engagement part (31a) and a cleat (32a) supported for pivotal motion, the fastening band being formed into a double loop shape (Li,Lo), a folded portion at one end of the fastening band being connected to the engagement part (31a) of the fastening buckle (30a) with a folded portion (22a) at the other end of the fastening band being passed over the cleat (32a) so that the fastening band forms an outer circumferential loop (Lo) and an inner circumferential loop (Li) to constitute the fastening device (10a) having a non-reversible self-lock mechanism in which the cleat (32a) is pivoted to clamp the folded portion (23a) around the cleat by a tension of the inner circumferential loop (Li), and the tire slip preventing apparatus being arranged in such a manner that joining portions at both ends of an anti-slip body wrapped around an outer circumference of a tire are connected to each other by the pair of hooks (36a,37a) so as to pass the fastening band along an edge of the anti-slip body on an outer surface of the tire, wherein the fastening device is constituted as a pair of fastening devices for right and left tires as viewed in the direction of vehicle travel and the pair of fastening devices are opposite to each other in the arrangement of the cleat (32a) and the engagement part (31a) of the fastening buckle as viewed from the outer surface of the tire so that the cleat (32a) is disposed ahead of the engagement part (31a) with respect to a tire rotation direction (R) in which a vehicle travels forward.
Patent EP-0873665-B1 (EP)
Title: Multiplexeur de service
Inventor: SMITH AVRIL JOY
IPC: H04Q11/04
Filed: 1997-01-08
Granted: 2004-10-06
Abstract: Multiplexeur de service (2) destiné à raccorder une pluralité de sources de signaux à un réseau de communication public commuté et transférant des données sous la forme de cellules de données transférées en mode asynchrone depuis une pluralité d'entrées (4) vers une sortie (6) afin d'établir la connexion avec le réseau. Le multiplexeur (2) comprend un régulateur de largeur de bande qui reçoit du réseau un signal correspondant à la largeur de bande disponible pour la transmission des cellules vers le réseau, et génère des signaux de commande en retour faisant que l'émission vers les sources de signaux entraîne au niveau de ces sources une modification de leurs cadences d'émission en fonction de la largeur de bande disponible. Un détecteur de niveau d'activité couplé au régulateur de largeur de bande surveille la largeur de bande des données reçues au niveau des entrées. Le multiplexeur permet de connecter les sources de signaux aptes à être commandées par le débit binaire disponible ou ABR à un seul point de desserte d'un réseau public fonctionnant en mode ABR de façon à réaliser, pour chaque source, une affectation de largeur de bande efficace et équitable.
Patent EP-1016187-B1 (EP)
Inventor: LEIJON MATS
IPC: H02K11/04
Filed: 1997-05-27
Granted: 2003-09-24
Abstract: A conductor and a rotating electric high-voltage machine that includes the conductor has a cable configured for high-voltage operation. The cable may be included as a winding for the rotating electric high-voltage machine. The conductor includes a first strand that is clad with an electrically insulating layer, and a second strand that is uninsulated whereas the first strand and the second strand are arranged in two or more layers of strands. The two or more layers of strands are insulated from one another. Furthermore, the first and second layers of the two or more layers of strands are arranged around a central core where the central core is at least one of an air core and a core of another material. The second strand is positioned so as not to be electrically contacting any other uninsulated strand.
Patent EP-0932613-B1 (EP)
Inventor: NOVICK RICHARD P
IPC: A61K38/00
Filed: 1997-05-22
Granted: 2005-03-09
Abstract: This invention provides peptides which inhibit agr transcription in S. aureus and thereby block the expression of virulence factors in S. aureus, pharmaceutical compositions comprising these peptides, as well as methods for treating or preventing an infection or disease caused by S. aureus using the peptides of the present invention.