baber/WOPTO huggingface dataset:
Patent NZ-594630-A (NZ)
Title: N-(3-amino-quinoxalin-2-yl)-sulfonamide derivatives and their use as phosphatidylinositol 3-kinase inhibitors
Inventor: BAJJALIEH WILLIAM
IPC: A61K31/498
Filed: 2006-10-09
Abstract: Disclosed herein is a process for preparing N-(3-amino-quinoxalin-2-yl)-sulfonamide derivatives of formula I, wherein the substituents are as defined within the specification, comprising: Reacting an intermediate of formula 5 with an intermediate of formula NHRaRb or HO-C1-C6-alkylenene-NHRaRb to yield a compound of formula I(c) or I(d); or Reacting an intermediate of formula 8, with an intermediate of formula 9(1), 9(b), 9(c), 9(d), 9(e), 9(f) or 9(g);wherein: 9(a) is HOC(O)-C1-C6-alkylene-N(R7a)(R7b), wherein Ra is R7a or a N-protecting group that is Boc or Fmoc; 9(b) is HOC(O)R9a; 9(c) is HOC(O)NR11aR11b; 9(d) is HOC(O)OR13a; 9(e) is HOCCO)-C1-C6-alkylene-N(R18b)C(O)R18a; 9(f) is HOC(O)-C1-C6-alkylene-C(O)R20a; 9(g) is LG-S(O)2R-C1-C6-alkylene-N(R21b)Ra, wherein Ra is R21a or a N-protecting group that is Boc or Fmoc; to yield a compound of formula I(e);or Reacting an intermediate of formula 11 with an intermediate selected from NHR8R8a, NH(R10)-C1-C6-alkylene-N(R10a)R10b, a cyclic amine, NH(R14)N(R14a)(R14b), NHR16-C1-C6-alkylene-C(O)OR16a, and NH(R19)-C1-C6-alkylene-C(O)R19a, to yield a Compound of Formula I; or Reacting an intermediate of formula 12 with an intermediate of formula NH(R7b)R7a to yield a Compound of Formula I(f); or reacting an intermediate of formula 13, with an intermediate of formula (a) to yield a compound formula I(h); and optionally further resolving individual isomers. Also disclosed are intermediates useful in the process disclosed above, namely: N-(3-(2-chloro-5-methoxy-phenylamino)quinoxalin-2-yl)-3-nitrobenzenesulfonamide; and 3-amino-N-(3-(2-chloro-5-methoxy-phenylamino)quinoxalin-2-yl)benzenesulfonamide.
Patent NZ-595290-A (NZ)
Title: Biomarker for monitoring patients
Inventor: ACRES BRUCE
IPC: G01N33/50
Filed: 2010-03-23
Abstract: Provided is an ex-vivo method for assessing the efficacy of a treatment in a patient receiving an immunogenic composition, wherein the method comprises: measuring levels of interferon gamma in a biological sample from the patient after the patient has received the immunogenic composition; wherein levels of interferon gamma above about 4 pg/ml indicate a successful clinical outcome for the treatment and wherein said immunogenic composition contains at least one recombinant viral vector expressing in vivo all or part of MUC antigen, provided that the recombinant viral vector does not express interferon gamma.
Patent NZ-597353-A (NZ)
Title: Online educational software
Inventor: GOUGOUSIS KANELLA
IPC: G06F21/22
Filed: 2011-12-22
Abstract: A method for educating a user about the use of an independent website comprises obtaining interactive web content from the website via a computer network; displaying the interactive web content and information to the user to educate the user about how to interact with the web content; receiving user input for a user interaction with the interactive web content; and prior to transmission of the user interaction to the website assessing the user interaction to determine whether the user interaction was in accordance with the information displayed to the user; and sending the user interaction to the website if the user interaction was in accordance with the information displayed to the user, or not sending the user interaction to the website if the user interaction was not in accordance with the information displayed to the user. Further disclosed is a computing device for educating a user about the use of an independent website comprising a memory; a network interface; and one or more processors connected to the memory, and configured to perform the above described method.
Patent NZ-603406-A (NZ)
Title: Moisture content analysis system
Inventor: CLARK RANDALL JAMES
IPC: A01F15/08
Filed: 2012-11-02
Abstract: An apparatus and a method for collecting data to determine a moisture content of a sample of plant material such as silage are disclosed. The apparatus comprises: an analysis chamber (209) bounded by a plurality of walls, a scanner (113) and an analysis conveyer (223). The analysis chamber includes an entrance and an exit, a first wall having an opening therein and there is a window covering the opening in the first wall. The scanner is positioned to project energy through the window into the analysis chamber onto the sample of plant material and to receive reflected energy from the sample of plant material through the window. The analysis conveyer to move the sample of plant material through the analysis chamber, the sample of plant material being compressed against the window as the sample of plant material is being moved through the analysis chamber. The analysis chamber is shaped to compress the sample of pant material against the window.
Patent NZ-603808-A (NZ)
Title: Closed fluid transfer system
Inventor: KOPLIN RANDALL SCOTT
IPC: A61J1/20
Filed: 2011-05-25
Abstract: 603808 A closed fluid transfer system for fluidly interconnecting a syringe to any one of a patient I.V. set, a vial and an I.V. bag, is provided and includes a first adapter defining a lumen and supporting a seal across a first end of its lumen, the first adapter supporting a rear end of a needle within the lumen, wherein the seal is movable relative to the needle such that a tip of the needle penetrates through the seal; and a second adapter defining a lumen and supporting a seal across a first end of its lumen; wherein when the second adapter is coupled to the first adapter, the second adapter seal abuts the first adapter seal and moves the first adapter seal relative to the tip of the needle such that the tip of the needle penetrates through the abutting first adapter seal and second adapter seal.
Patent NZ-628636-A (NZ)
Title: An accessory mount
Inventor: IAN JOHN DRAPIER
IPC: B60R9/055
Filed: 2014-08-12
Abstract: An accessory mount linking a tray or intermediate member to an accessory or accessory item. The tray or intermediate member includes two or more elongate members that are approximately vertically aligned, one member above the other. The accessory mount comprises two opposing flanged rigid frames linked about the two or more elongate members; a pair of flanged lips of the rigid frames abutting either side of a top and a bottom member and linked together via a fastener that passes through an opening between the elongate members; a fascia; and a bracket configured for connection to an accessory at a first end and to the fascia at a second end and to extend from the periphery of the fascia.
Patent NZ-707864-A (NZ)
Title: Measuring jig
Inventor: PITT JOHN
IPC: G06F17/50
Filed: 2013-11-08
Abstract: The invention provides a system for use in specification of a wheelchair. The system includes a measurement jig comprising at least one adjustable component to enable at least one measurement to be taken for bespoke configuration of the wheelchair. Measuring means are provided for taking measurements relating to the set configuration of adjustable components of the jig and a computer-implemented modelling component is arranged to generate a visual representation of the user sat in the wheelchair based on the user’s measurements. The system thereby reduces the possibility of error in the wheelchair specification process.
Patent NZ-708350-A (NZ)
Title: Anthelmintic compounds and compositions and method of using thereof
Inventor: MENG CHARLES Q
IPC: C07D417/12
Filed: 2013-11-19
Abstract: The present invention relates to anthelmintic compounds of formula (IA-1) below: wherein Y and Z are independently a bicyclic carbocyclic or a bicyclic heterocyclic group, or one of Y or Z is a bicyclic carbocyclic or a bicyclic heterocyclic group and the other of Y or Z is alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, heterocyclyl or heteroaryl, and variables X1, X6, X8, Q1, Q2, Q3, Q4, Q5, Q6, R1, R2, R3, Ring A, Ring B, W, m and n are as defined herein. The invention also provides for veterinary compositions comprising the anthelmintic compounds of the invention, and their uses for the treatment and prevention of parasitic infections in animals.
Patent NZ-713371-A (NZ)
Title: Stabilized soluble prefusion rsv f polypeptides
Inventor: LANGEDIJK JOHANNES PETRUS MARIA
IPC: C12N15/45
Filed: 2014-04-24
Abstract: The present invention provides stable pre-fusion respiratory syncitial virus (RSV) F polypeptides, immunogenic compositions comprising said polypeptides and uses thereof for the prevention and/or treatment of RSV infection.
Patent NZ-723148-A (NZ)
Title: Fgf-18 compound dosing regimen
Inventor: GUEHRING HANS
IPC: A61K38/18
Filed: 2015-02-20
Abstract: The present invention provides a new dosing regimen for administration of FGF18 in the treatment of a cartilage disorder, such as osteoarthritis or cartilage injury. Specifically provided is a preferred treatment scheme comprising administrations of an FGF-18 compound at least 3 times per treatment cycle, wherein said administrations are separated by about 4 weeks. The new dosing regimen can include the co-administration of a anti-inflammatory drug.
Patent NZ-742581-A (NZ)
Title: Methods and compositions for determining resistance to androgen receptor therapy
Inventor: SMITH NICHOLAS
IPC: C12Q1/68
Filed: 2013-07-26
Abstract: Described herein are modified androgen receptor polypeptides that are resistant to inhibition by an androgen receptor inhibitor. Described herein are compositions, combinations, and kits containing the modified androgen receptor polypeptides and methods of using the modified androgen receptor polypeptides. Also described herein are methods of using the modified androgen receptor polypeptides as screening agents for the identification and design of third-generation androgen receptor modulators. Also described herein are third-generation androgen receptor modulators that inhibit the activity of the modified androgen receptor polypeptides. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such androgen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions, including cancers, such as castration resistant prostate cancers, that are mediated or dependent upon androgen receptors.
Patent NZ-750197-A (NZ)
Title: Reduced diameter optical fiber and manufacturing method
Inventor: PASTOURET ALAIN
IPC: G02B6/02
Filed: 2016-07-29
Abstract: The invention relates to an optical fiber 1 comprising a core 2 and a cladding 3 surrounding the core 2 and having an outer diameter of 125μm, the optical fiber 1 comprising a cured primary coating 4 directly surrounding the cladding 3 and a cured secondary coating 5 directly surrounding the cured primary coating 4, said cured primary coating 4 having a thickness t1 between 10 and 18μm and an in-situ tensile modulus Emod1 between 0.10 and 0.18 MPa, said cured secondary coating 5 having a thickness t2 lower or equal to 18μm and an in-situ tensile modulus Emod2 between 700 and 1200 MPa, wherein said first and second thicknesses and said first and second in-situ tensile moduli satisfy the following equation: 4% < (t1 x t2 x Emod1 x Emod2 [3]) / (t1_norm x t2_norm x Emod1_norm x Emod2_norm [3])< 50%. Provides reduced size cable design while maintaining fiber performance in terms of micro bending losses and mechanical reliability under stress.
Patent NZ-756778-A (NZ)
Title: Methods of side passivation of adhesive rolls
Inventor: MITROVIC SLOBODAN
IPC: C09J7/00
Filed: 2018-03-02
Abstract: A method is disclosed for producing a passivation layer applied to the exposed sides of an adhesive roll which can tear to allow the adhesive roll to unwind. The passivation layer (1.1) is formed from at least one mass, the mass forming a tearable protective layer for a first side surface (4.1) of an adhesive roll (4) after drying and/or after a chemical reaction. The method comprises the following steps: a) coating at least one or both surfaces of a production substrate (2) for the passivation element (1) with the mass; b) at least partially drying and/or curing the layer (1a) to form a passivation layer (1.1).
Patent NZ-772974-A (NZ)
Title: Access node for end-to-end beamforming communications system
Inventor: MILLER MARK
IPC: H04B7/204
Filed: 2016-04-08
Abstract: A method of communication at an access node of a communication system comprising a plurality of access nodes at geographically distributed locations providing a communication service to user terminals distributed over multiple return user beam coverage areas via an end-to-end relay comprising multiple return receive/transmit signal paths, comprises receiving a return downlink signal comprising a composite return signal and a relay beacon signal from the end-to-end relay. The composite return signal comprises return uplink signals from a plurality of the user terminals relayed by the end-to-end relay. The method further comprises demodulating the relay beacon signal to obtain receive timing information; multiplexing the composite return signal with the receive timing information to obtain a multiplexed composite return signal; and sending the multiplexed composite return signal to a return beamformer for determining a return beam signal by applying return beam weights to the multiplexed composite return signal and at least one other multiplexed composite return signal, wherein the return beam weights account for wireless signal uplink paths up to the end-to-end relay, the multiple return receive/transmit signal paths through the end-to-end relay, and wireless signal downlink paths down from the end-to-end relay.
Patent PT-103729-A (PT)
Title: Estojo e processo para a detecção e identificação de leveduras de interesse clínico, através de uma amplificação isotérmica de adn seguida de hibridação com oligonucleótidos específicos, e respectivas utilizações.
Inventor: MARTINS ISABEL MARIA SPENCER VIEIRA
IPC: C12Q1/68
Filed: 2007-05-04
Abstract: A PRESENTE INVENÇÃO RELACIONA-SE COM UM PROCESSO PARA A DETECÇÃO E IDENTIFICAÇÃO DE LEVEDURAS DE INTERESSE CLÍNICO ATRAVÉS DA UTILIZAÇÃO DE UMA TÉCNICA DE AMPLIFICAÇÃO ISOTÉRMICA DE ADN, QUE UTILIZA OLIGONUCLEÓTIDOS INICIADORES NÃO ESPECÍFICOS PARA AMPLIFICAR UMA REGIÃO DO ADN RIBOSSÓMICO (P.E. DO RADN 265), SEGUIDA DE HIBRIDAÇÃO REVERSA DOS PRODUTOS MARCADOS (P.E. COM DIGOXIGENINA) COM UM PAINEL DE SONDAS DE OLIGONUCLEÓTIDOS (P.E. IMOBILIZADOS NUM SUPORTE SÓLIDO COMO UMA MEMBRANA DE NYLON) ESPECÍFICAS PARA CADA UMA DAS ESPÉCIES. A OCORRÊNCIA DE HIBRIDAÇÃO É SEGUIDAMENTE DETECTADA POR UM MÉTODO COLORIMÉTRICO. A PRESENTE INVENÇÃO RELACIONA-SE IGUALMENTE COM O DESENVOLVIMENTO DE UM ESTOJO, PARA A DETECÇÃO E IDENTIFICAÇÃO DE LEVEDURAS COM RELEVÂNCIA CLÍNICA, BASEADO NO REFERIDO PROCESSO. DESTA FORMA, O PRESENTE INVENTO É ÚTIL NA DETECÇÃO E IDENTIFICAÇÃO DE LEVEDURAS RELACIONADAS COM INFECÇÕES COM A VANTAGEM DE SE REVELAR UM MÉTODO SIMPLES, RÁPIDO, FIÁVEL E DE BAIXO CUSTO, PODENDO SER APLICADO NA ÁREA CLÍNICA, FARMACÊUTICA, VETERINÁRIA, ALIMENTAR E BIOTECNOLÓGICA.
Patent PT-110756-A (PT)
Title: Salto para sapato com capa amovível.
Inventor: MOSHE AZULAY
IPC: A43B21/24
Filed: 2018-05-23
Abstract: A PRESENTE INVENÇÃO DIZ RESPEITO A UM SALTO PARA SAPATO COM CAPA AMOVÍVEL QUE COMPREENDE UMA REENTRÂNCIA (1) VERTICAL ENTORNO DA ÁREA CIRCUNDANTE DO PERÍMETRO LATERAL DO CORPO VERTICAL DE UM SALTO PARA SAPATO (11), PARA O ENCAIXE E APREENSÃO DE UMA CAPA AMOVÍVEL (2) VERTICAL QUE COBRE A TODA A ÁREA CIRCUNDANTE DO PERÍMETRO LATERAL DE TODO CORPO VERTICAL DO SALTO PARA SAPATO (11) E UM SISTEMA DE APREENSÃO E REMOÇÃO PARA A RESPETIVA APREENSÃO E REMOÇÃO DA CAPA AMOVÍVEL (2) À REENTRÂNCIA (1) DO SALTO PARA SAPATO (11).
Patent PT-117579-A (PT)
Title: Dispositivo de estimulação elétrica direta para cultura de células, método e aplicações do mesmo
Inventor: NUNO ANDRÉ MARTINS SILVA
IPC: C12M3/00
Filed: 2021-11-16
Abstract: A PRESENTE DIVULGAÇÃO DIZ RESPEITO A UM DISPOSITIVO DE ESTIMULAÇÃO ELÉTRICA DIRETA PARA UMA PLACA DE CULTURA CELULAR (0102) COM UMA PLURALIDADE DE POÇOS PARA RECEBER LÍQUIDOS (0108) QUE COMPREENDEM CÉLULAS, EM QUE O REFERIDO DISPOSITIVO COMPREENDE: UMA TAMPA (0101) QUE COMPREENDE UMA PLURALIDADE DE PROTUBERÂNCIAS(0201), CADA UMA PARA SER INSERIDA NUM DOS POÇOS DA PLACA DE CULTURA, EM QUE CADA PROTUBERÂNCIA (0201) COMPREENDE PELO MENOS DOIS ELÉTRODOS (0104) PARA CRIAR UM CAMPO ELÉTRICO PARA ESTIMULAÇÃO EM CADA POÇO; UM GERADOR (0106) DE IMPULSOS ELÉTRICOS DE ESTÍMULO LIGADO ELETRICAMENTE (0105) AOS REFERIDOS ELÉTRODOS (0104); UM PROCESSADOR DE DADOS PARA CONTROLAR O REFERIDO GERADOR DE IMPULSOS ELÉTRICOS. A PRESENTE DIVULGAÇÃO DIZ AINDA RESPEITO AO MÉTODO PARA ESTIMULAÇÃO ELÉTRICA DIRETA PARA CULTURA CELULAR COMPREENDENDO O DISPOSITIVO DE ESTIMULAÇÃO ELÉTRICA DIRETA E AINDA O USO DO REFERIDO DISPOSITIVO.
Patent RU-94004121-A (RU)
Inventor: ARKHIPOV S V
IPC: A61F2/38
Filed: 1994-02-04
Abstract: FIELD: medicine; prosthesis. SUBSTANCE: stem 3 of knee joint prosthesis is embedded into canal of femur, and stem 4 is embedded into tibia canal. Screwed into canal of stem 3 by means of nut is device for spreading apart of tongs wedges for fastening the stem in bone canal. Device for spreading apart wedges 8 of tongs is screwed into canal of stem 8. Upon fastening of both stems 3 and 4 in canals of respective bones, socket of hinge is installed and secured in sleeve 16 of stem 4 and operative wound is sutured. EFFECT: higher reliability of prosthesis design and reduced possible complications. 1 cl, 4 dwg
Patent RU-94008239-A (RU)
Inventor: VORONIN V A
IPC: B62D55/247
Filed: 1994-03-10
Abstract: FIELD: transport engineering. SUBSTANCE: flexible track shoe of proposed design can be used on crawler vehicles and agricultural machines operation on water-logged soils. Flexible track shoe contributes for dissipation of energy transmitted from road wheels owing to internal friction, i.e. features dissipating properties. Middle resilient post in track shoe contributes to decrease in pressure transmitted to soil from vehicle frame and to uniform distribution of pressure over support surface. EFFECT: enlarged operating capabilities.
Patent RU-94023094-A (RU)
Inventor: LYCHEV N V
IPC: B25B15/00
Filed: 1994-06-15
Abstract: FIELD: mechanical engineering. SUBSTANCE: to bring the tool into working state the slit in glass 6 is made coincident with longitudinal notch 4 on housing-handle 1 in which chosen working body is. The latter passes through slit and takes upper working position in irregularly-shaped hole. EFFECT: expanded manufacturing capabilities at the expanse of placing several working bodies in one housing. 1 cl, 10 dwg
Patent RU-94023251-A (RU)
Inventor: KHAJNTS DEBELL
IPC: C07K1/20
Filed: 1994-07-04
Abstract: FIELD: protein chemistry. SUBSTANCE: method involves the synthesis and purification of hydrophobic polypeptides, proteins and peptides. Also, fusion proteins were proposed which were used for preparing and purification of hydrophobic polypeptides, proteins or peptides mentioned above. Also, homogeneous monomeric b-amyloid peptide is proposed and test for screening drugs that inhibit toxicity of medicinal preparation amyloid and using monomeric b-amyloid peptide mentioned above. EFFECT: improved method of synthesis.
Patent RU-94023363-A (RU)
Inventor: ZHIRNOV E N
IPC: B07B1/18
Filed: 1994-06-20
Abstract: FIELD: separation of both grainy loose and viscous and suspension materials for given classes by size used in mineral resources dressing, normalization of grain and cereals, production of building materials, other branches of industry, that require materials separation by size. SUBSTANCE: method provides for material separation under action of centrifugal forces. According to method requirements material for separation is formed as concentrated ring-type volume under simultaneous relative transfer of by pulsed braking. Apparatus for realization of the method has body with lid and mounted in body rotor with perforated shell. In the apparatus rotor shell has ring-type slot perforation, rotor inside there is disturbing member of separated particles relative transfer. Perforation of rotor shell as a version is made in the form of continuous ring-type slot. Rotor is made of blocks of ring-type sections with clearance between rings, size of which is increasing in direction of material removal. Apparatus has stabilizing member mounted in rotor and disturbing member is mounted between rotor shell and stabilizing member and it is fixed on lid of body. EFFECT: method and apparatus for material separation allow to increase effectiveness of material separation of process. 2 dwg
Patent RU-94033506-A (RU)
Inventor: AGAFONOV V D
IPC: F16J15/16
Filed: 1994-09-14
Abstract: FIELD: mechanical engineering. SUBSTANCE: end seal contains rubber ring and U-shaped collar which are located between parts to be sealed. Lateral parallel walls of collar overlap the ring which presses them to parts. Center portion of collar made in form of outer portion of torus is flexible. Collar is engageable with parts by means of end circular projections passed in starting chamfers of parts. EFFECT: increased service life of joint; enhanced reliability; reduced force applied to flywheel.
Patent RU-94038539-A (RU)
Inventor: VASIL EV A V
IPC: H02G11/00
Filed: 1994-10-12
Abstract: FIELD: electrical engineering, and namely, devices for supply of electric power carriers to movable loads. SUBSTANCE: the device is a chain, having two branches of hinge-joined links with relative turn locks. The chain branches are interconnected by clamps uniformly spaced along the chain, whose one end is rigidly secured on the object fixed part, and the other - on the rotary one. The links of one chain branch have a larger spacing on centers than the links of the other branch. Each hinge link is bent, it is formed by two rectilinear sections located at an angle to each other, the bend angle for all chain links is the same. EFFECT: simplified design and small dimensions, reliable in service. 5 dwg
Patent RU-94042578-A (RU)
Inventor: NIKOLAEV I V
IPC: C12N15/56
Filed: 1994-12-01
Abstract: FIELD: genetic engineering, microbiology. SUBSTANCE: invention proposes fragment of DNA PCG12 encoding synthesis of β--galactosidase. This fragment is used as a base for construction of plasmid pPCG12. Also, invention proposes the strain Penicillium canescens "ВКПМ" F-715 that is a producer of β--galactosidase. On medium with beet pulp and "БВК" the proposed strain accumulates β--galactosidase at concentration up to 190-220 U/ml cultural fluid for 96 h fermentation. EFFECT: increased accumulation of β--galactosidase by P, canescens.
Patent RU-95101079-A (RU)
Inventor: MISJURA P P
IPC: H01H33/66
Filed: 1995-01-25
Abstract: FIELD: electrical engineering. SUBSTANCE: vacuum arc-control chamber has evacuated case accommodating two electric contact members mounted for relative displacement. Steam-condensing screen placed between walls of evacuated case and contact members has its surface facing contact members and its roughness in at least intensive material deposition region is between 5 and 100 mcm. EFFECT: facilitated manufacture; reduced screen manufacturing time.
Patent RU-95104082-A (RU)
Inventor: ONISHCHENKO E F
IPC: A61B5/02
Filed: 1995-03-21
Abstract: FIELD: medicine; cardiology. SUBSTANCE: method involves taking a dose of nitroglycerin (0.15 mg/10 kg of body weight) one minute prior to functional breathing sampling against the background of contrasting right departments of the heart. Subsequent discharge of the contrast into the left auricle at the moment of the functional sampling with the contrasting right auricle is indicative of a defect of the interatrial septum. EFFECT: higher diagnosis reliability.