baber/WOPTO huggingface dataset:
Patent UA-119046-C2 (UA)
Inventor: GROSSMAN TAMAR R
IPC: C12N15/113
Filed: 2014-12-09
Abstract: Винахід належить до сполуки, що здатна інгібувати експресію фактора В комплемента (CFB), яка містить модифікований олігонуклеотид, що складається з 20 зв'язаних нуклеозидів, що має послідовність нуклеотидних основ, яка складається з будь-якої з SEQ ID NO: 440, 198, 228, 237, 444, 448, 450, 453 і 455, або 16 зв'язаних нуклеозидів, що має послідовність нуклеотидних основ, яка складається з SEQ ID NO: 549 або 598, при цьому зазначений модифікований олігонуклеотид містить: геп-сегмент, що складається зі зв'язаних дезоксинуклеозидів; сегмент 5'-крило, що складається зі зв'язаних нуклеозидів; і сегмент 3'-крило, що складається зі зв'язаних нуклеозидів; при цьому геп-сегмент розташований між 5'-сегментом-крилом і 3'-сегментом крилом, і при цьому кожен нуклеозид кожного сегмента-крила містить 2'-O-метоксіетил-цукор або cEt-цукор; при цьому кожен міжнуклеозидний зв'язок являє собою фосфоротіоатний зв'язок, і при цьому кожен цитозин є 5-метилцитозин Також винахід стосується композиції, що містить заявлену сполуку, способу лікування заявленою сполукою захворювання, пов'язаного з дисрегуляцією альтернативного шляху активації комплемента та застосування заявленої сполуки в лікуванні захворювання, пов'язаного з дисрегуляцією альтернативного шляху активації комплемента.
Patent UA-118280-C2 (UA)
Title: Fused heterocyclic compound
Inventor: SASAKI MINORU
IPC: C07D307/81
Filed: 2015-12-02
Abstract: A fused heterocyclic compound having an enteropeptidase inhibitory action and use of the compound as a medicament for treatment or prophylaxis of obesity, diabetes mellitus, etc., are provided. Specifically, a compound represented by the following formula (I): wherein each symbol is as defined herein, or a salt thereof and use of the compound as a medicament for treatment or prophylaxis of obesity, diabetes mellitus, etc., are provided. EMBED ISISServer (I)
Patent UA-124182-C2 (UA)
Title: Method for improving solubility of protein and peptide by using immunoglobulin fc fragment linkage
Inventor: LIM HYUNG KYU
Filed: 2015-03-31
Abstract: The present invention relates to: a method for improving the solubility of a physiologically active protein or peptide, compared to a physiologically active protein or peptide to which an immunoglobulin Fc fragment is not linked, comprising a step of linking the physiologically active protein or peptide to the immunoglobulin Fc fragment; and a composition for improving the solubility of a physiologically active protein or peptide, containing an immunoglobulin Fc fragment and exhibiting improved solubility compared with that of a composition not containing the immunoglobulin Fc fragment.
Patent UA-118222-C2 (UA)
Title: Спосіб поетапного омолодження шкіри обличчя біоадсорбуючою пілінг-пластинкою за індріксоном
IPC: A61Q19/08
Filed: 2016-11-24
Abstract: Винахід належить до медицини, зокрема до дерматології, косметології та естетичної медицини і стосується способу поетапного омолодження шкіри обличчя біоадсорбуючою пілінг-пластинкою, який включає на першому етапі обстеження шкіри обличчя, постановку діагнозу та лікування, на другому етапі готують біоадсорбуючу пілінг-пластинку з водостійкого паперу, який змазують рідкою желатиною, наносять на нього шар активованого вугілля середньої щільності і сушать, на третьому етапі ех tempore готують суміш з 30-75 мл універсального зволожуючого крему Nivea Creme та 5-15 мл 30 % олійного розчину вітаміну Е, ретельно їх змішують і наносять суміш товстим шаром на вимиту та висушену шкіру, на четвертому етапі біоадсобуючою пілінг-пластинкою шліфують за масажними лініями шкіру обличчя протягом 10 хвилин, на п'ятому етапі ретельно змивають шкіру обличчя від залишків крему і візуально оцінюють результат, а при необхідності повторюють процедуру через 6 тижнів.
Patent UA-124520-C2 (UA)
Title: Method for making assembled textile products
Inventor: SALVETTI SERGIO
Filed: 2016-01-25
Abstract: A method tor making assembled textile products comprising the following steps: arranging an open piece of fabric, made by producing a tubular knitted fabric (1) by means of a circular knitting machine for hosiery or for knitwear, by pulling the tu-bular fabric (1) over a support (2) so as to stretch the tubular fabric (1), by applying a heat adhesive material (4) onto at least a first portion of an outer surface of the tubular fabric (1) pulled over the support (2) letting the heat adhesive material (4) firmly adhere under heat onto the tubular fabric (1), and by cutting the tubular fabric (1) onto which the heat adhesive material (4) has been ap-plied, so as to obtain an open piece (9) of fabric; cutting the open piece of fabric according to predefined cutting lines for making one or more parts of a textile product to be assembled, and assembling a plurality of parts obtained from the open piece (9) of fabric or from a plurality of pieces of fabric for obtaining an assembled textile product, in particular a jacket, a pair of trousers, a men's suit, a women's dress.
Patent UA-120076-C2 (UA)
Title: Sealing valve arrangement for a shaft furnace charging installation
Inventor: HUTMACHER PATRICK
Filed: 2016-09-06
Abstract: A sealing valve arrangement for a shaft furnace charging installation, said arrangement comprising: a shutter arranged for cooperating with a valve seat; an integrated dual-motion shutter-actuating device for moving said shutter between a sealed closed position in sealing contact with the valve seat and an open position remote from the valve seat, said integrated dual-motion shutter-actuating device comprising: - a primary motion assembly for moving said shutter from said sealed closed position to an undamped position wherein the shutter is released from the valve seat; - a secondary motion assembly for tilting said shutter from said undamped position to said open position remote from the valve seat, said secondary motion assembly comprising a tilting arm carrying said shutter and connected to a tilting shaft that defines an axis of rotation and a tilting shaft actuator configured to impart an angular rotation about said axis to said tilting arm; wherein said integrated dual-motion shutter-actuating device further comprises a stationary outer cylindrical sleeve, wherein said primary motion assembly comprises an inner eccentric sleeve shaft rotationally mounted within said outer cylindrical sleeve and a primary motion actuator configured to impart angular rotation to said inner eccentric sleeve shaft, the primary motion being a function of the eccentricity and angular rotation of the inner eccentric sleeve shaft; and wherein said tilting shaft of said secondary motion assembly is rotationally mounted within said inner eccentric sleeve shaft of said primary motion assembly, the secondary motion being a function of the angular rotation of the lilting shaft.
Patent UA-126163-C2 (UA)
Title: Enantiomers of substituted thiazoles as antiviral compounds
Inventor: KLEYMANN GERALD
Filed: 2018-10-04
Abstract: The present invention relates to novel antiviral compounds with specific stereoconfiguration, especially to specific novel enantiomers, to a process for their preparation and to their use as medicaments, in particular as antiviral medicaments.
Patent UA-127104-C2 (UA)
Title: Aerosol generating device including induction coil
Inventor: LEE JAE MIN
Filed: 2020-05-19
Abstract: Disclosed is an aerosol generating device comprising: a receiving space cylindrically formed in order to receive a cigarette therein; an induction coil wound around the outer surface of the receiving space; a power unit for supplying electric power to the induction coil; a control unit for controlling the electric power supplied to the induction coil; and a shielding film including a ferromagnetic body for preventing electromagnetic interference due to electromagnetic waves emitted from the induction coil, wherein the shielding film surrounds only a part of the outer surface of the induction coil in order to prevent electromagnetic interference due to an electromagnetic wave having a frequency which does not exceed 500 kHz.
Patent UA-77210-C2 (UA)
Title: Macrolids, process for their manufacture (variants), pharmaceutical composition, method for treatment of bacterial infections
IPC: A61P31/04
Filed: 2002-11-13
Abstract: The invention relates to 14 or 15-membered macrolids substituted in position 4'', formula (I) (I) and their pharmaceutically acceptable salts and solvates, the methods for their manufacture, and their use in the treatment and the prevention of the systemic or local bacterial infections.
Patent DE-19747623-C5 (DE)
Title: Wellrohr zur schützenden Ummantelung elektrischer Leitungen
Inventor: KRAFT STEFAN
IPC: F16L11/11
Filed: 1997-10-28
Granted: 2008-09-18
Abstract: Aus
einem elastischen Kunststoffmaterial hergestelltes Wellrohr zur
schützenden
Ummantelung elektrischer Leitungen mit einer längs einer Mantellinie verlaufenden
schlitzförmigen Öffnung,
deren den Schlitz ausbildende Ränder
Verschließvorrichtungen
aufweisen, wobei das Wellrohr (1) elastisch deformierbar ist und
in seiner formstabilen offenen Grundstellung spannungslos ist, die
Verschließvorrichtung
(5) an dem einen Rand (3) als eine über seine gesamte Länge verlaufende
und nach innen offene Rinne (7) und die Verschließvorrichtung
(6) an dem anderen Rand (4) als eine über seine gesamte Länge verlaufende
und nach außen
offene Rinne (8) ausgebildet ist, dadurch gekennzeichnet, daß  die
sich jeweils gegenüberliegenden
Wandungen (9 bzw. 10) der Rinnen (7 bzw. 8) in radialer Richtung
verlaufen, und die der Wandung (9) der nach innen offene Rinne (7) gegenüberliegende
Wandung (10) der nach außen
offenen Rinne (8) in Form einer Verlängerung (11) zum Rohrinneren
abgebogen ist und eine Aufgleitfläche (12) für die gegenüberliegende Wandung (9) der
nach innen offenen Rinne...
Patent RU-2620783-C9 (RU)
Inventor: Senik Aleksej Vasilevich
IPC: H04B10/25
Filed: 2015-09-07
Granted: 2017-07-26
Abstract: Изобретение относится к области лазерной техники и касается устройства ввода импульсного лазерного пучка в волоконно-оптическую линию связи. Устройство включает в себя фокусирующую систему линз и волоконный световод с коллектором. Фокусирующая система линз выполнена в виде m линз, размещенных в плоскости, ортогональной направлению пучка, причем форму, количество, размер и фокусное расстояние линз подбирают исходя из условия полного перекрытия сечения входного пучка и заданной длины устройства. В качестве волоконного световода с коллектором используется m-канальный волоконный световод. Технический результат заключается в уменьшении длины устройства. 2 з.п. ф-лы, 1 ил.
Patent RU-2740132-C9 (RU)
Inventor: Obedkov Evgenij Gennadevich
IPC: A61L31/08
Filed: 2019-04-28
Granted: 2021-04-01
Abstract: FIELD: medicine. 
     SUBSTANCE: invention refers to intra-abdominal plasty in ventral hernias and discloses a method of applying a collagen stimulating coating on an endoprosthesis. Method is achieved due to fact that components of substance mixed until homogeneous mass are dried and applied to surface by immersion of prosthesis, characterized in that homogeneous mass is obtained by dissolving in Solcoseryl methyl cellulose, prepared solution is held at temperature 4 °C for 24 hours, homogenized and aerated at 20 °C for 2 hours, endoprosthesis is immersed into the obtained substance for 60 minutes, after which the endoprosthesis is removed and exposed to drying in air at temperature 20 °C for 5 hours. 
     EFFECT: invention makes it possible to reduce labor intensity of obtaining of endoprosthesis cover adapted to surrounding biological tissues and stimulating healing and can be widely used in preparing endoprosthesis with stimulant preparations. 
     3 cl, 1 ex
Patent DK-9593-D0 (DK)
IPC: A63H3/46
Filed: 1993-01-27
Abstract: PCT No. PCT/DK94/00043 Sec. 371 Date Oct. 18, 1995 Sec. 102(e) Date Oct. 18, 1995 PCT Filed Jan. 26, 1994 PCT Pub. No. WO94/16788 PCT Pub. Date Aug. 4, 1994A toy figure having rotatable arms which protrude from the body of the figure. The arms are rotationally coupled to each other so that they have a limited mutual rotatability.
Patent DK-15389-D0 (DK)
Inventor: LOEFFLER FRIDOLIN
IPC: C12N9/14
Filed: 1989-01-13
Abstract: A macerating enzyme preparation is produced by contacting an aqueous solution of an enzyme mixture containing pectin glycosidases and pectinesterase obtained from an Aspergillus culture with a cation exchanger, separating the liquid phase, in which most of the pectin- esterase is located, from the cation exchanger, and eluting the macerating enzyme preparation from the latter.
Patent DK-19886-D0 (DK)
Inventor: FOCKS HUBERT
IPC: B65D88/52
Filed: 1986-01-16
Abstract: The interchangeable body for lorries and trailers comprises a floor frame (1) whose external longitudinal carriers (2) are connected on the outside to crane pocket fittings (3) and hinges (4) for foldable side walls (5), the lower narrow side of which in the folded-up position is located directly above the crane pocket fittings (3) and next to the external longitudinal carriers (2) of the floor frame (1). The external longitudinal carriers (2) of the floor frame are designed as low profile carriers. The surface (18) of the crane pocket fittings (3) is situated approximately at half the height of the external longitudinal carriers and the side walls (5) are provided in the region above the crane pocket fittings (3) with a protective strip (20) placed on them, the external surface of which is approximately flush with the external surface of the crane pocket fittings (3). <IMAGE>
Patent DK-29786-D0 (DK)
Inventor: RINIO JOHANNES
IPC: B66D3/18
Filed: 1986-01-21
Abstract: An arrangement for a faultless clamping of a rope (16) in a traction sheave (1) for lifting, lowering or pulling loads, comprising two sheave halves (7, 14) which are spring-loaded pressed together, and comprising, at the periphery of the V-shaped groove (2), fixedly mounted rope-supporting elements (20).
Patent DK-81387-D0 (DK)
Inventor: POR-HSIUNG LAI
IPC: C07K1/14
Filed: 1987-02-18
Abstract: Chromatographic procedures are individually and jointly applied to the rapid and efficient isolation of biologically active proteins and especially glycoproteins such as recombinant erythropoietin present in the medium of growth of genetically transformed mammalian host cells. Illustratively, recombinant EPO is isolated from culture fluids by reverse phase chromatography employing a C4 or C6 column and elution with ethanol. Recombinant erythropoientin may also be purified by anion exchange chromatography employing, e.g., a DEAE resin, with preliminary selective elution of contaminant materials having a lower pKa than erythropoietin from the resin under conditions mitigating against acid activated protease degradation. Practiced serially, the two chromatographic procedures allow for high yields of biologically active recombinant erythropoietin from mammalian cell culture media.
Patent HU-910543-D0 (HU)
Title: Process for solid-phase synthetizing of 1h-rh analogues
Inventor: NESTOR JOHN J
IPC: C07K14/575
Filed: 1991-02-19
Abstract: A solid phase synthesis of LH-RH analogs in which the amino acids serine and histidine, if present, are side chain protected during the synthesis with groups labile to selected  alpha -amino or deprotecting agents.
Patent DK-145785-D0 (DK)
Inventor: ERICSSON MAGNUS
IPC: G01N31/22
Filed: 1985-04-01
Abstract: A method and a device for producing predetermined and defined varying concentration patterns of chemically or biologically active substances in chemical or biological qualitative or quantitative determinative methods, the method comprising application of the substance(s) within part of or the whole of a rectangular area of a medium in a concentration pattern having at least one concentration maximum and one concentration minimum: the device comprising a rectangular carrier on which the substance(s) have been applied so that the concentration pattern(s) thereof exhibit at least one concentration maximum and one concentration minimum.
Patent DK-160286-D0 (DK)
Inventor: MUSTONEN ARVO
IPC: H04H20/67
Filed: 1986-04-09
Abstract: The invention relates to a synchronization method for radio transmitters of a local, e.g. nationwide paging network. A paging network is connected to a public switched telephone network and comprises a paging network unit (PNU), transmitter group controllers (TGC) and transmitter site interfaces (TSI). All controllers are provided with means for receiving, processing and transmitting messages in digital form. Base stations are provided with radio transceivers (Tx, Rx) transmitting radio signals intended for paging or for synchronization of the base stations covering a common overlap area. With the method of the invention, synchronization is performed on the basis of a synchronization plan composed by paging network unit (PNU) and synchronization commands based on the plan. Synchronization proceeds sequentially in a certain order so that each base station (except for the initiator) first receives and then transmits a synchronization signal. Prior to the transmission of a synchronization signal, compensation of delays is executed based on one hand on receiving own transmission and, on the other hand, on information given by the paging network unit PNU about distances between base stations. The synchronous transmission of paging information is confirmed to be independent of a digital data transmission network by determining the exact time of radio transmission of each page according to a plan made beforehand by the paging network unit.
Patent DK-170588-D0 (DK)
Inventor: KAERCHER RALPH W
IPC: A23L17/40
Filed: 1988-03-28
Abstract: Thermally processing seafood, e.g. shrimp, is performed in the presence of a mixture of an acid and its lactones, preferably a mixture of an aldonic acid and its lactones whereby, without need for salt, the texture and flavor of the seafood are maintained through thermal processing and storage. The preferred mixture is obtained by combining the seafood with glucono-delta lactone, and the mixture is comprised of gluconic acid with its lactones, glucono-delta lactone and glucono-gamma lactone.
Patent DK-238383-D0 (DK)
Inventor: SEGAUD CHRISTIAN
IPC: C09C3/12
Filed: 1983-05-27
Abstract: Molding compositions for the fabrication of shaped articles having enhanced mechanical properties are comprised of (i) a polymeric matrix, (ii) an inorganic reinforcing filler material therefor, and, advantageously, (iii) a polymer/filler coupling agent, said reinforcing filler material consisting essentially of intimate admixture of enstatite and silica advantageously prepared by calcination of a precursor clay at a temperature of at least 800 DEG C.
Patent DK-265688-D0 (DK)
Inventor: ROSENSTEIN ROBERT W
IPC: G01N33/548
Filed: 1988-05-13
Abstract: An assay method for determining an analyte in a sample comprises the steps of:- providing a solid support (12) with a sample to be assayed, the solid support including a first portion (14, 18), a second portion (13, 17) and a third portion (15, 16), the third portion including a binder for the analyte, the first portion of the support receiving the sample, and the second portion receiving a tracer; moving tracer and sample by capillary flow from the second and first portions to the third portion to provide contact between tracer, binder and sample to thereby provide a complex, in the third portion, of any analyte in the sample, binder and tracer; and determining tracer in the third portion of the support or tracer which has passed through the third portion of the support to determine analyte. Apparatus suitable for use in the method comprises:- a solid support (12) inlcuding first (18), second (17) and third (16) absorbent material portions, the first portion including a sample receiving portion (14), the second portion including a tracer receiving portion (13), the third portion including a binder for the analyte to be assayed, the third portion being in capillary flow communication with both the sample and tracer receiving portions to provide for capillary flow of sample and tracer to the third portion to provide contact between tracer, sample and binder.
Patent DK-324886-D0 (DK)
Inventor: PETRI ALBERTO
IPC: C07D251/70
Filed: 1986-07-08
Abstract: Branched, soluble, high-molecular-weight, thermoplas­tic polycarbonates having improved properties, and, in particular, suitable to the fabrication by blow-moulding, characterized by the presence in their structure of units deriving from the use in the synthesis of tris(4'-hydrox­yaryl)-amino-S-triazines having the formula: wherein R₁ and R₂, equal to, or different from each other, indicate hydrogen, linear or branched C<sub>1-5</sub> alkyl, or halogen (in particular, chlorine and bromine).
Patent DK-332688-D0 (DK)
Inventor: STEER PETER LESLIE
IPC: A61F5/44
Filed: 1988-06-17
Abstract: An outlet pipe or tap is secured to a liquid containing bag (10) by trapping the bag outlet region (12) between inner (16) and outer nested funnels (14). A leak proof seal is provided by disposing an O-ring (18) sealing means between the funnels and moving one funnel axially relative to the other.
Patent DK-334083-D0 (DK)
Inventor: RAISIN HELMUT
IPC: C09B1/34
Filed: 1983-07-20
Abstract: The present invention relates to a process for the differential dyeing of such polyamide fibres and materials containing polyamide fibres as are made of components which differ in dyeability, or mixtures of polyamide fibres, with dyes or dye mixtures, which comprises using for dyeing these materials an aqueous liquor which contains a dye of the formula    <IMAGE>  (1)  in which A1 is hydrogen or C1-4alkyl and R is a C2-5-alkanoyl, C3-6-alkenoyl, (C1-4-alkoxy)carbonyl, phenoxycarbonyl, C1-4-alkylsulfonyl or phenylsulfonyl radical which can be substituted in the alkyl, alkenyl, alkoxy, phenoxy or phenyl moiety, or a mixture of a dye of the formula (1) with a monosulfo-containing anthraquinone dye, and to those dyes of the formula (1) in which A1 is as defined above and R is a C1-4-alkylsulfonyl or phenylsulfonyl radical which can be substituted in the phenyl moiety by C1-4-alkyl. Even at low dyeing temperatures, the process of the invention gives ombré effects rich in contrast and, on admixture of other suitable acid dyes, multicolor effects on polyamide fibres which are suitable for differential dyeing.
Patent DK-378984-D0 (DK)
Inventor: UMEZAWA HAMAO
IPC: C12P13/00
Filed: 1984-08-03
Abstract: The present invention relates to an improved process for producing arphamenine by fermentation. According to this process arphamenine can be obtained in high yields by adding amino acids to the culture medium.
Patent DK-542785-D0 (DK)
Inventor: LIVINGSTON DOUGLAS ALAN
IPC: C07H15/16
Filed: 1985-11-22
Abstract: A process for preparing a 7-halodeoxylincomycin or an analogue thereof, which comprises reacting lincomycin or an analogue thereof with a thionyl halide and dimethylformamide, under mild conditions.
Patent DK-653089-D0 (DK)
Inventor: OHTA MITSUAKI
IPC: C07D235/06
Filed: 1989-12-21
Abstract: 4,5,6,7-Tetrahydrobenzimidazole derivatives (I) and salts thereof show 5-HT3 antagonizing activity <CHEM>  wherein R<1>, R<2>, R<3> independently represent hydrogen atom, hydroxy group, a halogen atom, a lower alkyl group which may optionally be substituted with a halogen atom, a lower alkoxy group, a lower alkylthio group, an aralkyloxy group, an aryloxy group, a lower alkanoyl group, carboxy group, a lower alkoxycarbonyl group or nitro group; R<4>,R<5> and R<6> can each be a hydrogen atom or a lower alkyl group; and X is an oxygen atom or sulfur atom. d
Patent HU-893393-D0 (HU)
Title: Fine colestipole-hydrocloride
Inventor: MCCURDY VINCENT E
IPC: A61K/
Filed: 1989-05-24
Abstract: The present invention provides a novel fine milled form of a known pharmaceutical composition, colestipol hydrochloride. This fine milled form of colestipol hydrochloride yields pharmaceutically elegant dosage forms exhibiting increased potency, including non-gritty oral powders and high dose oral tablets (e.g., 1000 mg tablets). Conventional colestipol hydrochloride was heretoforth available in spherical granules which produced less elegant (gritty) oral suspensions and oral tablets with substantially lower doses of drug (e.g., ca 500 mg).