baber/WOPTO huggingface dataset:
Patent CA-3125348-A1 (CA)
Title: Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
Inventor: IMRAN MIR
IPC: A61K9/22
Filed: 2019-12-31
Abstract: Embodiments of the invention provide swallowable devices, preparations and methods for delivering therapeutic agents (TA) within the GI tract. Many embodiments provide a swallowable device such as a capsule for delivering TAs into the intestinal wall (IW) or other GI location. Embodiments also provide various TA preparations such as IgG that are configured to be contained within the capsule, advanced from the capsule into the IW and degrade to release the TA into the bloodstream where they exhibit a selected plasma concentration profile which may have selected pharmacokinetic parameters. The preparation can be operably coupled to a delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the IW. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.
Patent CA-3127474-A1 (CA)
Inventor: FISHER TERRENCE
IPC: G01N33/48
Filed: 2020-03-27
Abstract: L'invention concerne des méthodes de traitement du cancer consistant à déterminer certains niveaux de biomarqueurs du patient avant le traitement.
Patent CA-3128777-A1 (CA)
Inventor: SIEBER LINDSEY B
IPC: A47C27/14
Filed: 2021-08-23
Abstract: Mattress toppers for mattress assemblies generally includes a convoluted foam layer including a convoluted upper surface and a bottom planar surface.    The convoluted upper surface includes multiple raised rectangular-shaped foam sections and a plurality of raised spaced apart hemispherical-shaped foam spheres within each of the raised rectangular shaped foam sections; and at least one overlying foam layer including a bottom planar surface in contact with an uppermost surface of the multiple raised rectangular-shaped foam sections.
Patent CA-3128944-A1 (CA)
Inventor: UHRMEISTER PETER
IPC: A24F47/00
Filed: 2020-01-31
Abstract: An electronic cigarette is provided, wherein the electronic cigarette has a mouthpiece portion with a liquid store (5), and a power supply portion (3) with a power source and electrical circuitry. The electronic cigarette has a display (19) configured to display an image; the display (19) is integrated into the housing of the electronic cigarette. The display (19) can be integrated into the housing of the liquid store (5), and the housing of the liquid store (5) can be at least partially transparent. The display (19) can be at least partially transparent, and can be an OLED display.
Patent CA-3132834-A1 (CA)
Inventor: ROBICHAUX JACQULYNE
IPC: A61P35/00
Filed: 2020-03-27
Abstract: The present disclosure provides methods of treating cancer in a patient determined to have an HER2 exon 21 mutation by administering a third-generation tyrosine kinase inhibitor, such as poziotinib.
Patent CA-3133329-A1 (CA)
Title: Needle insertion device for the electroporation of a product into an eye
Inventor: LAFFITTE JEAN-DENIS
IPC: A61N1/32
Filed: 2020-04-24
Abstract: The present invention relates to a device comprising: - a support (4) comprising a support base (10) defining - a spherical base contact surface (18), extending along a virtual sphere (S) and - a circular rim (20) extending in a rim plane (P20); - a first and a second needle (8a;8b) mobile on the support between extracted and inserted positions in which the first and second needles are outside and maximally inserted in said virtual sphere, respectively, via first and second intermediate piercing positions in which, respectively, the first and second needles extend along first and second insertion axis (?<sub>8a</sub>;?<sub>8b</sub>) and their tips are located on first and second insertion points (M<sub>8a</sub>;M<sub>8b</sub>) belonging respectively to first and second hemispheres of the virtual sphere separated by a "median radial plane of the rim", an angle (?) between the median radial plane and any insertion axis being between 70° and 110°.
Patent CA-3133880-A1 (CA)
Title: Pyrolyse de dechets polymeres
Inventor: STAPELA ANNELIE
IPC: C10B53/07
Filed: 2020-03-19
Abstract: L'invention concerne un procédé de pyrolyse et un réacteur de pyrolyse pour la décomposition thermique de déchets polymères, en particulier de déchets de caoutchouc et de matières plastiques, au moyen d'un procédé de pyrolyse rapide, le déchet étant amené dans une chambre pyrolytique (1), et étant chauffé à une température de décomposition du déchet par un rayonnement micro-ondes.
Patent CA-3136318-A1 (CA)
Title: Conception de manchon en acier a ressort
Inventor: WELLS COREY M
IPC: E02F9/28
Filed: 2020-03-12
Abstract: Ressort (400) qui comprend un premier bras de ressort (428) s'étendant à partir du premier bord latéral (418) de la base plate (406'). Le premier bras de ressort (428) comprend une première partie arquée (430) s'étendant à partir de la base plate (406'), une première partie droite (432) s'étendant à partir de la première partie arquée (430) et disposée à proximité de la face arrière (416), la première partie droite (432) définissant un premier angle obtus (434) avec la face arrière (416), et une première longueur de partie droite (436).
Patent CA-3138081-A1 (CA)
Title: Methods of treating chronic spontaneous urticaria using a bruton's tyrosine kinase inhibitor
Inventor: BHATTACHARYA SOUVIK
IPC: A61K31/505
Filed: 2020-05-20
Abstract: The present disclosure relates to methods for treating Chronic Spontaneous Urticaria using a compound of Formula (I) or a pharmaceutically acceptable salt thereof. Also disclosed herein is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, for treating Chronic Spontaneous Urticaria patients, as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.
Patent CA-3138613-A1 (CA)
Inventor: LAPORTE BRADLEY KEITH
IPC: B29C48/00
Filed: 2020-05-20
Abstract: L'invention concerne un appareil et des procédés de fabrication de pailles pour boire biodégradables et compostables à partir d'un matériau de polyhydroxyalcanoate (PHA). Un tel appareil peut comprendre une trémie qui contient un matériau de PHA brut, une extrudeuse qui reçoit le matériau de PHA brut de la trémie et produit un matériau de PHA extrudé, un ou plusieurs bains d'eau qui refroidissent le matériau de PHA extrudé, un extracteur qui extraie un flux tubulaire de matériau de PHA à travers le système, et un dispositif de coupe qui est conçu pour couper le flux de matériau de PHA en pailles finies. Les pailles finies peuvent être biodégradables dans le sol et en mer, ainsi que compostables à domicile ou industriellement.
Patent CA-3140334-A1 (CA)
Title: Balancing ring anti-rotation spacer
Inventor: PELLERIN HUGUES
IPC: F01D5/02
Filed: 2021-11-23
Abstract: A rotating assembly for a gas turbine engine has a balancing ring mounted to a first rotating component having a rotating unbalance about an axis of rotation. The ring is clocked at a circumferential position about the axis to counteract the rotating unbalance.  A spacer is axially abutted against the first rotating component to set an axial position of the first rotating component relative to a second rotating component. The balancing ring is locked against rotation relative to the first rotating component in its circumferential position by the dual use spacer.
Patent CA-3141426-A1 (CA)
Inventor: MELDRUM ERIC
IPC: C07C237/42
Filed: 2020-06-25
Abstract: The present invention relates to a new class of tertiary amine derivatives of formula (I) and their uses for treating viral infections, particularly viral respiratory infections. The present invention further relates to pharmaceutical compositions comprising compounds of formula (I).
Patent CA-3141639-A1 (CA)
Inventor: KAPS CHRISTIAN
IPC: A61K35/32
Filed: 2020-06-02
Abstract: La présente invention concerne un procédé pour multiplier ou enrichir des cellules cartilagineuses et fournir des sphéroïdes correspondants, les sphéroïdes étant utiles pour un produit d'implantation de chondrocytes autologues (ACI). Ainsi, l'invention concerne en particulier la production de sphéroïdes à partir de cartilage articulaire et leur utilisation.
Patent CA-3145826-A1 (CA)
Title: Facade panel with integrated window system
Inventor: LANG OLIVER
IPC: E04B2/88
Filed: 2020-07-02
Abstract: A prefabricated construction element for use in construction of multi-storey buildings. The construction element is a mass timber exterior wall panel, integrating building assemblies such as windows, exterior wall finishes, and connectors to other building components. The construction element comprises: an envelope subpanel; a feature element such as a window or door; an insulation layer; and a cladding layer, wherein the envelope subpanel comprises an upper beam along its top edge and a lower beam along its bottom edge, and a plurality of spacers disposed between the upper beam and the lower beam, defining one or more openings for receiving the feature element; wherein the insulation layer is attached to the envelope subpanel and provided with one or more openings corresponding to the feature element; wherein the cladding layer overlies the insulation layer and is attached thereto.
Patent CA-3146314-A1 (CA)
Title: System and method for web-based customer check-in
Inventor: KAISER PETER
IPC: G06Q30/00
Filed: 2008-08-20
Abstract: A web-based system and method allows customers to remotely check-in to a wait list for a service from a business. A website associated with the business is provided through which an address submitted by the customer can be received. Multiple locations of the business in the vicinity of the address and wait times for the service at each location can then be geographically displayed. A selection by thc customer of a location at which to receive the service can be received and the customer can then be placed on a waiting list for the selected location. The multiple locations can be displayed on a map showing the relative proximity of the address and the locations and driving directions from the address to the selected location can be provided. The wait times can be calculated using historical data related to the performance of the service at each location, such as the amount of time that employees at the location have taken to perform the service in the past.
Patent CA-3147582-A1 (CA)
Inventor: NUSSINOVITCH AMOS
IPC: A23B4/10
Filed: 2020-07-15
Abstract: The present invention relates to a method for forming a protective coating on a plant tissue, the method comprising consecutives steps of: (a) providing a plant having an external surface, wherein a portion of the external surface comprises an exposed surface; (b) applying a first aqueous solution comprising a crosslinking agent to the external surface of the plant; and (c) applying a second aqueous solution comprising a polysaccharide, which is susceptible to crosslinking by the crosslinking agent, to the external surface of the plant, thereby forming a protective coating on the exposed surface of the plant. Further provided is a postharvest plant matter comprising a first segment, which is covered by natural skin; and a second segment, which has an exposed surface, wherein the second segment is coated by a protective coating comprising a polysaccharide and the first segment is essentially free of said protective coating.
Patent CA-3147690-A1 (CA)
Title: Polypeptide complex for conjugation and use thereof
Inventor: JIN MINGZHI
IPC: A61K39/395
Filed: 2020-07-17
Abstract: The disclosure generally relates to the fields of immunology, cell biology, molecular biology and medicine. More particularly, it concerns polypeptide complex for conjugation and use thereof. A polypeptide complex comprising, from N-terminus to C-terminus, a Fab domain operably linked to a hinge region is provided, wherein the Fab domain and the hinge region are derived from different IgG isotypes, or part thereof. The polypeptide complex further comprises a Fc polypeptide which is operably linked to the hinge region. The present disclosure provides an antibody drug conjugate comprising a polypeptide complex of the present disclosure. A pharmaceutical composition comprising an antibody drug conjugate of the present disclosure and a pharmaceutically acceptable carrier or excipient, a method of preparing the antibody drug conjugate, the use of the polypeptide complex in the manufacture of the antibody drug conjugate, a method of treating a condition in a subject in need thereof with a therapeutically effective amount of the antibody drug conjugate are also provided. The subject inventions according to the present disclosure provide improved payload-antibody ratio of antibody bio-conjugation, in particular for therapeutic applications.
Patent CA-3148251-A1 (CA)
Title: Courroie en v a ligne de cables centrale
Inventor: SEDLACEK DOUGLAS R
IPC: F16G5/06
Filed: 2020-07-23
Abstract: L'invention concerne une courroie en V à ligne de câbles centrale, laquelle courroie comprend une ligne de câbles, centrée radialement, de câbles de traction enroulés de manière hélicoïdale intégrés dans une gomme d'adhésion à module très élevé, une couche de dessus de câbles et une couche de dessous de câbles. La gomme d'adhésion a un module sensiblement isotrope, tandis que les couches de dessus de câbles et de dessous de câbles ont une anisotropie dans des modules dans le sens des grains et dans le sens transversal aux grains. Les modules dans le sens transversal aux grains de dessus de câbles et de dessous de câbles sont inférieurs au module de la gomme d'adhésion. Les modules anisotropes sont le résultat de fibres courtes orientées et le module dans le sens des grains est orienté axialement dans la courroie. La gomme d'adhésion n'a de préférence pas de fibre courte. La courroie n'a de préférence pas de couche de tissu de renfort et pas d'enveloppe de tissu. La gomme d'adhésion, la couche de dessus de câbles et la couche de dessous de câbles sont de préférence à base d'un élastomère éthylène-alpha-oléfine, avec un durcissement au peroxyde, une charge de renfort et un sel métallique d'un acide organique a-ß-insaturé. La courroie peut avoir des encoches sur l'une ou les deux des surfaces radiales interne et externe pour une souplesse supplémentaire.
Patent CA-3148909-A1 (CA)
Title: Fluid pump with a rotor
Inventor: SCHECKEL MARIO
IPC: A61M60/808
Filed: 2009-12-04
Abstract: The invention relates to a fluid pump, in particular to a liquid pump having a rotor (18) with at least one rotor blade (20, 21) for conveying the fluid, the rotor being variable with respect to its diameter between a first, compressed state and a second expanded state. In order to produce simple compressibility and expandibility of the rotor of the pump, it is provided according to the invention that at least one rotor blade is deformable between a first state which it assumes in the compressed state of the rotor and a second state which it assumes in the expanded state of the rotor by means of a fluid counterpressure (23) during a rotation of the rotor during pump operation.
Patent CA-3150196-A1 (CA)
Inventor: SOLOVIEV VADIM
IPC: G06T11/00
Filed: 2020-08-14
Abstract: La plupart des algorithmes de reconstruction d'image sont communs à DT et CT, et nécessitent une attribution de volume de reconstruction et sont basés sur des techniques de traçage de rayon. Des images tridimensionnelles reconstruites deviennent disponibles uniquement après que le volume entier est traité et que l'algorithme s'achève. La présente invention réalise une reconstruction sur une base tranche par tranche, au lieu d'attendre l'achèvement de l'algorithme par rétroprojection de chaque pixel dans chaque image d'atténuation vers l'émetteur qui a généré cette image, sur une tranche de reconstruction sélectionnée et par détermination d'une proportion de chevauchement avec des cellules de grille dans la tranche pour obtenir des facteurs de pondération afin de calculer une intensité de rétroprojection moyenne pour chaque cellule de grille dans la tranche de reconstruction sélectionnée.
Patent CA-3156516-A1 (CA)
Title: Catalysts for pet methanolysis
Inventor: SHARPE ROBERT JACKS
IPC: C07C67/54
Filed: 2020-12-10
Abstract: Provided is a process for depolymerization of a poly(C2-C4 alkylene terephthalate), which comprises contacting a poly(C2-C4 alkylene terephthalate) with methanol and a catalyst chosen from potassium carbonate, sodium carbonate, magnesium methoxide, 1,8-diazabicyclo[5.4.0]undec-7-ene, and triazabicyclodecene, at a temperature sufficient to effect said depolymerization. The process of the invention can be carried out a substantially lower temperature and requires less methanol than necessary for zinc acetate-catalyzed reactions, and is sufficiently robust to tolerate lower-quality poly(C2-C4 alkylene terephthalate) scrap feeds.
Patent CA-3156523-A1 (CA)
Title: Computer-controlled power takeoff driven motorized pump system
Inventor: STUBBS RUSTEE
IPC: E02F9/22
Filed: 2020-11-02
Abstract: A computer-controlled motorized pump system is provided. A generator is mechanically connected to a power takeoff. A first controller receives AC power from the generator and converts the AC power to DC power and provides DC power to a computing system that has one or more processors and one or more computer-readable hardware storage media and a user interface. A second controller is directly coupled to the first controller and provides AC power to a motor. The motor is mechanically connected to a pump, and the motor is in communication with, or controlled by, the computing system.
Patent CA-3162217-A1 (CA)
Title: Procedes et dispositifs pour mettre a jour des informations de configuration de n?ud iab pendant une migration inter-donneur
Inventor: CAO KUN
IPC: H04W36/00
Filed: 2020-03-06
Abstract: La présente divulgation concerne des procédés, des systèmes et des dispositifs pour mettre à jour des informations de configuration pour un n?ud de liaison terrestre d'accès intégré (n?ud IAB) de migration pendant une migration inter-donneur d'un donneur IAB source à un donneur IAB cible. Un procédé comprend la fourniture, par une unité centrale (CU) donneuse IAB cible, d'informations de configuration pour une unité distribuée (DU) de n?ud IAB de migration dans un message de commande de ressources radio (RRC) dédié pendant la préparation d'un transfert intercellulaire. Le procédé comprend en outre l'envoi, par la CU donneuse IAB cible, d'un message XnAP à une CU source donneuse IAB, le message XnAP comprenant les informations de configuration en tant que conteneur transparent RRC, puis la CU source donneuse IAB envoie le message RRC dédié à une terminaison mobile (MT) de n?ud IAB de migration, le message RRC dédié comprenant les informations de configuration.
Patent CA-3162316-A1 (CA)
Inventor: FAIZAKOF AVRAHAM
IPC: G10L25/30
Filed: 2020-12-21
Abstract: A method comprising: receiving a plurality of audio segments comprising a speech signal, wherein said audio segments represent a plurality of verbal interactions; receiving labels associated with an emotional state expressed in each of said audio segments; dividing each of said audio segments into a plurality of frames, based on a specified frame duration; extracting a plurality of acoustic features from each of said frames; computing statistics over said acoustic features with respect to sequences of frames representing phoneme boundaries in said audio segments; at a training stage, training a machine learning model on a training set comprising: said statistics associated with said audio segments, and said labels; and at an inference stage, applying said trained model to one or more target audio segments comprising a speech signal, to detect an emotional state expressed in said target audio segments.
Patent CA-3162557-A1 (CA)
Title: System and method for recording ownership in digital real estate in a digital platform
Inventor: MARUSYK RANDALL WILLIAM
IPC: G06F16/28
Filed: 2022-06-10
Abstract: The invention relates to a method and system for recording ownership and transfer of digital real estate. A method automates digital assets generation associated with digital real estate located within a digital platform. The method also includes determining a unique owner identification code associated with the second party, generating a digital asset associated with the digital real estate. The method transmits the unique digital real estate ID code and the unique owner ID  code to record a transfer of the digital asset to the second party. It also determines a new unique owner ID code of the third party, links the digital asset with the new unique owner ID  code and transmits the unique digital real estate ID code and the new unique owner ID code to the distributed block-chain ledger for recordation on a new transaction block.
Patent CA-3169389-A1 (CA)
Title: Method and system for extending push-to-talk service from land mobile radio systems to broadband systems
Inventor: MCDONALD DANIEL J
IPC: H04W4/10
Filed: 2021-03-11
Abstract: A method and system for processing a Push To Talk (PTT) call at an alternate bearer gateway. The alternate bearer gateway is connected to a Land Mobile Radio (LMR) Core Network and a Broadband Network. The alternate bearer gateway receives a PTT message from either the LMR Core Network or the Broadband Network. The PTT message includes a talkgroup identifier and a message. When the PTT message is received from the LMR Core Network, the alternate bearer network determines at least one Broadband talkgroup member using the talkgroup identifier. The alternate bearer gateway sends the message to the Broadband talkgroup member via the Broadband Network. When the PTT message is received from the Broadband Network, the alternate bearer gateway sends the message to the LMR Core Network.
Patent CA-3172118-A1 (CA)
Inventor: VIETH REINHOLD W
IPC: A63B63/00
Filed: 2021-07-22
Abstract: La présente invention concerne un procédé simple pour jouer à un sport à comptage de buts, subaquatique et en un-contre-un, ainsi que le champ de jeu adéquat, le projectile et l'appareil cible. Lorsqu'il est immergé, un joueur offensif lance le projectile vers l'appareil cible subaquatique défendu par un joueur de défense qui essaie de toucher le joueur offensif avant qu'il ne fasse le lancement, ou qui essaie d'empêcher le projectile de toucher la zone cible. Des variantes du projectile et de l'appareil cible sont également décrites en tant qu'options pour une utilisation dans le sport.
Patent CA-3172339-A1 (CA)
Inventor: DAHAL LILA RAJ
IPC: C03C17/34
Filed: 2021-02-18
Abstract: A coated glass article provides a visible light reflecting, solar control glazing with a low emittance, a low solar heat gain coefficient, and a low shading coefficient that can significantly improve energy costs in buildings and homes while providing a desirable neutral color for, at least, film side reflection. The low emittance characteristic of the 5 glazing would minimize any indirect heat gain from absorption.
Patent CA-3174652-A1 (CA)
Inventor: MONFARED AMIN
IPC: F28D7/16
Filed: 2021-04-21
Abstract: La technologie de l'invention comprend un dispositif de chauffage de fluide comprenant une chambre de combustion tronconique et un échangeur de chaleur qui peut comporter des tubes de chauffage. La chambre de combustion peut comporter une première extrémité et une seconde extrémité qui est en communication fluidique avec les tubes de chauffage. La surface de la seconde extrémité de la chambre de combustion peut être plus grande que la surface de la première extrémité de la chambre de combustion.