baber/WOPTO huggingface dataset:
Patent PT-1283217-E (PT)
Title: Antibodies against the il-8 receptor, and their therapeutic uses
Inventor: OLSON PATRICIA A TEKAMP
IPC: A61K38/00
Filed: 1994-09-13
Abstract: Inhibitors, including antibodies, of IL8 binding to its receptors, that interact with the amino-terminal extracellular domain of the IL8 receptor and which compete with IL8 for receptor-binding, are disclosed. The inhibitors are useful modulators of IL8 receptor-mediated biological activity.
Patent PT-1363600-E (PT)
Title: Liquid formulations for the prevention and treatment of mucosal diseases and disorders
Inventor: JACOB JEREMY E
IPC: A61K9/00
Filed: 2002-02-15
Abstract: Stable, viscous, mucoadhesive aqueous compositions which are useful for the prevention and treatment of ulcerative, inflammatory, and/or erosive disorders of mucous membranes and/or the delivery of pharmaceutically active compounds to mucosal surfaces for topical treatment or transfer to the systemic circulation.
Patent PT-1601361-E (PT)
Title: Pyridylsulfonamido pyrimidines for treating diabetic nephropathy
Inventor: MANN JESSICA
IPC: A61K31/506
Filed: 2004-03-03
Abstract: The present invention relates to the use of a compound of formula (I) <CHEM> wherein R1 is pyridyl or thiazolyl, any of which may optionally be substituted with C1-8alkyl or C2-8alkenyl ; and  a) R2 is methoxy and n is zero or one; or b) R2 is chlorine and n is zero  and pharmaceutically acceptable salts thereof for the treatment of diabetic nephropathy.
Patent PT-1729486-E (PT)
Title: Method for personalizing a portable communication device, and associated portable communication device
Inventor: LE MINH
IPC: H04M1/72448
Filed: 2005-05-30
Abstract: The present invention relates to a method for personalizing the working of a portable communication device (1), characterized in that it comprises an initialization step (A 0 ) during which multimedia content data files are stored (A 01 ) in a removable memory (18) of said portable communication device, and personalization parameters for controlling peripherals (2, 17) of said device are set (A 02 ) with software links to at least some of said data files; and further comprising, prior to removal of said removable memory (18), a step (A 03 ) for creating a table including said software links, and a step (A 2 ) for copying, according to said table, said data files for which software links exist or at least a transformation of said data files, from said removable memory (18) to an internal memory (7) of said portable communication device.
Patent PT-1761528-E (PT)
Title: 5-amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2h-pyrido[2,3-d]pyrimidine derivatives and related compounds for the treatment of cancer
Inventor: SAKAI TOSHIYUKI
IPC: C07D487/04
Filed: 2005-06-10
Abstract: The present invention relates to a pyrimidine compound represented by the following formula [I]   
wherein each symbol is as defined in the specification, a pharmaceutically acceptable salt thereof, and a pharmaceutical agent for the prophylaxis or treatment of a disease caused by undesirable cell proliferation, particularly an antitumor agent, which contains such compound. The compound of the present invention has superior undesirable cell proliferation suppressing action, particularly, an antitumor action, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, antirheumatoid agent and the like. In addition, by the combined use with other antitumor agent such as alkylating agent, metabolism antagonist and the like, it can be a more effective antitumor agent.
Patent PT-1973795-E (PT)
Title: Closure device
Inventor: KAUSHAL KUL BHUSHAN
IPC: B65D41/34
Filed: 2006-12-29
Abstract: A closure device includes a base (1) and a top (23). The base (1) has an aperture (13) and the top (23) has an aperture (27). The top (23) is movable laterally relative to the base (1) between a first position in which the aperture (13) of the base and the aperture (27) of the top are not in alignment and a second position in which the apertures are in alignment. Biasing spring (22, 43) is provided with in the top so as to extend laterally between the base and the top with a free end of the biasing spring urging the top towards the first position in which the apertures (13, 27) are not in alignment.
Patent PT-2032175-E (PT)
Title: Cosmetic product sterilization
Inventor: LOPEZ DIDIER
IPC: A61L2/04
Filed: 2007-06-21
Abstract: The invention relates to a method for sterilizing a cosmetic product, in which said product consists of a fluid circulating under regulated pressure in a sterilization circuit (1), according to the viscosity of said fluid. The invention also relates to the device for implementing such a method.
Patent PT-2053063-E (PT)
Title: Recognition molecules for treatment and detection of tumours
Inventor: GOLETZ STEFFEN
IPC: A61K51/08
Filed: 2004-01-23
Abstract: Recognition molecules (I) comprising sequences that bind specifically to the glycosylated MUC1 tumor epitope, are new. New recognition molecules (I) comprise: (a) sequences (1) or (2); (b) sequences (3) or (4) and (c) sequences (5) and (6), and bind specifically to the glycosylated MUC1 tumor epitope. Asp-Ala-Trp-Met-Asp (1) Asn-Tyr-Trp-Met-Asn (2) Glu-Ile-Arg-Ser-Lys-Ala-Asn-Asn-His-Ala-Thr-Tyr-Tyr-Ala-Glu-Ser-Val-Lys-Gly (3) Glu-Ile-Arg-Leu-Lys-Ser-Asn-Asn-Tyr-Thr-Thr-His-Tyr-Ala-Glu-Ser-Val-Lys-Gly (4) Gly-Gly-Tyr-Gly-Phe-Asp-Tyr (5) His-Tyr-Tyr-Phe-Asp-Tyr (6) Independent claims are also included for the following: (1) construct (II) comprising (I) fused, chemically coupled or non-covalently associated with additional sequences and/or structures; (2) isolated nucleic acid (III) that encodes (I) or (II); (3) expression cassette or vector that contains (III), operatively linked to a promoter; (4) virus or host cell comprising at least one cassette or vector of (3); (5) organism containing at least one host cell of (4); (6) method for preparing (I) and (II); and (7) kit containing (I) and/or (II). ACTIVITY : Cytostatic. No details of tests for cytostatic activity are given. MECHANISM OF ACTION : Specific binding to the MUC1 epitope; Gene therapy.
Patent PT-2493341-E (PT)
Title: A smoking system having a liquid storage portion and improved airflow characteristics
Inventor: THORENS MICHEL
IPC: A24F40/485
Filed: 2010-10-26
Abstract: There is provided a smoking system comprising a capillary wick for holding liquid, at least one air inlet, at least one air outlet and a chamber between the air inlet and air outlet. The air inlet, the air outlet and the chamber are arranged so as to define an air flow route from the air inlet to the air outlet via the capillary wick so as to convey aerosol formed from the liquid to the air outlet. The smoking system further includes at least one guide for channeling the air flow in the air flow route, so as to control particle size in the aerosol.
Patent PT-680414-E (PT)
Inventor: JONES KIRK G
IPC: B29C33/38
Filed: 1993-01-29
Abstract: There is disclosed a hollow-form wheel formed entirely by injection molding of plastic. The wheel has an integral, central sleeve to receive a wheel hub assembly, at least three, hollow-form, integral spokes that are symmetrically located at equal angular spacings about the hub, and an integrally formed annular rim having a peripheral channel to receive a tire. The wall thickness of the sidewalls of the rims and spokes and the central hub area of the wheel are of uniform thickness to provide the strength and stiffness propeties at least equal to those of a metal spoked wheel.
Patent PT-719766-E (PT)
Inventor: HORI MANABU
IPC: C07D265/36
Filed: 1995-12-21
Abstract: A 1,4-benzoxazine derivative of the following formula (I): <CHEM> or a pharmaceutically acceptable salt thereof is disclosed. The compound of the present invention is useful as a medicament for preventing or treating disorders induced by intracellular acidosis during myocardial ischemia, such as cardiac dysfunction, myocardial necrosis, arrhythmia, reperfusion injury, and the like, which are observed in ischemic heart diseases (e.g. myocardial infarction, angina pectoris, etc.).
Patent PT-771209-E (PT)
Inventor: DEFEO-JONES DEBORAH
IPC: A61K47/48
Filed: 1995-06-07
Abstract: Oligopeptides which comprise amino acid sequences that are recognized and proteolytically cleaved by free prostate specific antigen (PSA) are described. Also described are assays which comprise such oligopeptides useful for determining free PSA protease activity in vitro and in vivo. Therapeutic agents which comprise conjugates of such oligopeptides and known cytotoxic agents are also described.
Patent PT-867504-E (PT)
Inventor: MITCHINSON COLIN
IPC: C12N1/21
Filed: 1994-02-10
Abstract: A mutant alpha-amylase is provided that is the expression product of a mutated DNA sequence encoding an alpha-amylase, the mutated DNA being derived from a precursor alpha-amylase, which is a Bacillus alpha-amylase, by substitution or deletion of an amino and at a position equivalent to M + 15 in B licheniformis alpha-amylase. The mutant alpha-amylase are suitable for use in detergent compositions and in process for starch liquification.
Patent PT-1115384-E (PT)
Inventor: NYSTROM CHRISTER
IPC: A61K31/445
Filed: 1999-09-24
Abstract: A pharmaceutical composition for the treatment of acute pain by sublingual administration is described. The composition comprises an essentially water-free, ordered mixture of fentanyl or a pharmaceutically acceptable salt thereof in the form of microparticles which are adhered to the surface of carrier particles which are substantially larger than the particles of fentanyl, and are essentially water-soluble. In a preferred embodiment, the composition also contains a bioadhesion and/or mucoadhesion promoting agent. The invention also relates to the preparation of the composition, and to the use of the composition for the treatment of acute pain.
Patent PT-1131260-E (PT)
Inventor: SCHUMANN KLAUS
IPC: B65H35/00
Filed: 1999-11-13
Abstract: The invention relates to a method for dispensing flat forms, such as labels, stickers, transdermal therapeutic systems, flat medicaments for oral application, etc, in a controlled manner. According to said method, the outer contour of the flat form (103) is punched out from a strip-shaped starting material and connecting bridges (105) hold the flat form (103) and the edge of the punched layer together. These connecting bridges (105) break when the flat forms are dispensed via a deflector edge (106). The inventive method can be advantageously used for packing individual flat forms in primary packaging. The invention also relates to a specialised punching device used in the method.
Patent SG-68085-G (SG)
Title: A method for producing olefins and/or ethers of high octane number
IPC: C07C41/00
Filed: 1985-09-14
Abstract: A wide olefinic C2 to C10 stream is restructured over a special zeolite catalyst to form primarily C4 to C7 olefins, the C4 to C7 isoolefins are reacted with methanol over an acid catalyst to form high octane ethers, and unreacted olefins and methanol separated from the ether product are recycled to the olefin restructuring operation.
Patent IE-34896-L (IE)
Title: 1, 4-dihydropyridines
IPC: C07D405/04
Filed: 1971-01-18
Abstract: 1,4-Dihydropyridines of the formula: <IMAGE> wherein R is hydrogen, straight, branched or cyclic lower alkyl, lower alkenyl, or lower alkinyl, unsubstituted or substituted; or benzyl, or phenethyl, unsubstituted or substituted in the aryl portion; R' is alkyl of 1 to 4 carbon atoms; R'' is alkenyl of 2 to 6 carbon atoms, alkinyl of 2 to 6 carbon atoms, cyclic alkenyl of 3 to 6 carbon atoms interrupted by oxygen, alkenyl of 2 to 6 carbon atoms or alkinyl of 2 to 6 carbon atoms interrupted by 1 or 2 oxygen atoms, or alkenyl of 2 to 6 carbon atoms or alkinyl of 2 to 6 carbon atoms substituted by hydroxyl; and R'''is unsubstituted or substituted aryl; cyclohexyl; benzyl; styryl; pyridyl; pyrimidyl; furyl; thienyl; pyrrolyl; pyridyl, pyrrolyl, thienyl or furyl substituted by alkyl of 1 or 2 carbon atoms; or substituted pyrimidyl: <IMAGE> are useful for their coronary dilating effect, their nitrite-like effect on the heart, their anti-fibrillation effect, their vascular-spasmolytic effect and muscular-spasmolytic effect, and as anti-hypertensives.
[US4048171A]
Patent CU-21028-L (CU)
Inventor: VOGEL CHRISTIAN
IPC: C07C233/07
Filed: 1973-05-15
Abstract: Los compuestos de la fórmula I en la que: A - Significa una cadena etilénica insustituida o una cadena etilénica monosustituida por etilo o mono o di-substituida por metilo y R2 - Significa metilo, etilo, n-propilo o isopropilo, alilo, metilalido con inclusión del grupo crotílico, ciclopropilo o ciclopropilmetilo.
Patent IE-840163-L (IE)
Title: Electroacoustic transducers
IPC: H04R9/04
Filed: 1984-01-25
Abstract: To assemble the diaphragm unit of a transducer such as that of Application No. 8203650 (Serial No. 2114855), the central dome-shaped part (4) of the diaphragm is pushed through the outer annular part (9) and the coil (11) is wound on a cylindrical skirt on the dome (4). Next the outer annular part (9) is moved forwards until its cylindrical skirt is close to the coil (11). Then the two parts are fixed together. <IMAGE>
[GB2134746A]
Patent IE-900172-L (IE)
Title: Cooling hydroscopic powders
IPC: A23C1/04
Filed: 1990-01-16
Abstract: Hygroscopic powders, especially fat-containing milk products, are cooled by being fluidized in cooling air. Dehumidification of the drying air is omitted and overdrying prior to cooling to compensate powder rehumidification during cooling is avoided by using a closed cycle cooling in which the spent cooling air after efficient dust removal and re-cooling is used as cooling and fluidizing air.
[EP0379461A1]
Patent IE-830309-L (IE)
Title: Electrically activated detonator
IPC: F42D1/04
Filed: 1983-02-15
Abstract: An improved electrically actuated detonator for use in oil well perforation guns is described wherein a hermetically sealed donor explosive propels a plate through a barrel cavity into a vented open space to initiate an acceptor explosive. If the open space fills with liquid the detonator fails to operate. The detonator is also resistant to actuation by radio-frequency and electrostatic energy.
[US4441427A]
Patent IE-44790-L (IE)
Title: Moulding apparatus.
IPC: B29B15/00
Filed: 1977-04-07
Abstract: Apparatus for molding elastomeric articles is disclosed, the apparatus including an injection unit having an open-ended chamber in which elastomeric stock is disposable and from which such stock can be expelled, a multi-cavity mold having cavities aligned with corresponding ones of the apertures of the end plate, a device for moving the injection unit and mold relative to one another to engage the mold with the end plate, and a pneumatic venting system for evacuating fluid entrapped in each of the mold cavities preparatory to filling the latter with elastomeric stock from the injection unit. The foregoing abstract is neither intended to define the invention disclosed in the specification, nor is it intended to limit the scope of the invention in any way.
[US4140470A]
Patent IE-39353-L (IE)
Title: Sterile connector for conduits.
IPC: B25B27/02
Filed: 1974-03-28
Abstract: A sterile connector for the end of a conduit employed in the passage of blood or of blood components which comprises a resilient, deformable gasket disposed about the terminal end of a conduit, a continuous, removable yieldable flexible strip material, a portion of which is removably adhered to said gasket and overlies the end of said conduit, said strip material having a free end, said strip material being in a generally U-shaped configuration, whereby a force applied to the free end thereof withdraws the entire strip material to expose the end of said conduit; a method of joining the ends of two conduits together in a sterile manner so that blood or its components can pass therethrough which comprises providing each end with a connector as described above, arranging them in face-to-face alignment so that the ends of the conduit are in registry, drawing the connectors together so that the gasket of each connector is deformed inwardly and so that the free ends of the strip material are substantially parallel and withdrawing the strip material from each of said connectors at the same time; a pair of conduits joined together by a pair of facing connectors as described above.
Patent IE-45752-L (IE)
Title: Homeopathic composition for erythema solare
IPC: A61K36/28
Filed: 1977-05-06
Abstract: A composition active with respect to erythema solare, which comprises a mixture of tinctures of Apis mellifica at a dilution of from 4 DEG CH to 15 DEG CH and Calendula at a dilution of from a third decimal to 9 DEG CH.
[US4163049A]
Patent IE-39246-L (IE)
Title: Preparing a purified extract of quillaia bark
IPC: A61K8/97
Filed: 1974-05-02
Abstract: 1430885 Quillaia extract LABORATOIRE L LAFON 1 May 1974 [3 May 1973] 19001/74 Heading C2U [Also in Divisions A5 and C5] Purified extract of Quillaia bark, substantially free from tannins, in which the bark is subjected to repeated extraction by an extracting solvent, the combined liquid extracts are evaporated to dryness, warm water is added to the residue, tannins are precipitated by means of an organic complexing substance comprising cinchonine, egg albumen or polyvinylpyrrolidone, and the purified extract is recovered, is useful in cosmetics and shampoos.
[GB1430885A]
Patent FI-823876-L (FI)
Inventor: GIOENI MARY LOUISE
IPC: C08J3/24
Filed: 1982-11-11
Abstract: Polymer blends containing ammonium liposalt emulsion polymer are useful as or in coating compositions, binders for non-woven fabrics, adhesives and similar products. The blends comprise emulsion acid copolymer and emulsion halohydroxypropyl and/or propylene oxide ammonium liposalt copolymer at least one of which is film forming. The invention embraces a process for producing tough, solvent resistant products and such products derived from the process.
Patent FI-853904-L (FI)
Inventor: CLEARY MICHAEL TERENCE
IPC: C07C67/56
Filed: 1985-10-08
Abstract: Saturated fatty acids differing in chain length by at least two carbon atoms can be separated by contacting a feed mixture containing the acids at adsorption conditions with an adsorbent comprising a crystalline silica having a silica to alumina mole ratio of at least 12:1, thereby selectively adsorbing the longer-chain saturated fatty acid. The remainder of the feed mixture is then removed from the adsorbent, and the selectively adsorbed acid recovered from the adsorbent by desorption at desorption conditions with a desorbent liquid soluble in the feed mixture and having a polarity index of at least 3.5.
Patent IE-39797-L (IE)
Title: Packed wire netting coils
IPC: B65D59/00
Filed: 1974-06-10
Abstract: This invention relates to a packing for a wire netting coil having protective end covers on each end and a method of packing such wire netting coil. The packing includes a wrapping sheet tightly enclosing the coil and a protective cover on each end of the coil, each cover having a tongue hingedly connected thereto.
[US3929226A]
Patent IE-36107-L (IE)
Title: Pharmaceutical compositions; indole derivatives
IPC: C07D401/06
Filed: 1971-11-19
Abstract: 1318300 Indole-derived ketones and ketimines LABAZ 22 Nov 1971 [9 Dec 1970] 58543/70 Heading C2C The invention comprises compounds of formula and their pharmaceutically acceptable acid addition salts, wherein R 1 is H, C 1-4 alkyl, cyclohexyl or Ph (possibly p-Cl, F or MeO- substituted); R 2 , R 5 are each H or C 1-4 alkyl; R 3 is H, C 1-4 alkyl, Cl or MeO; R 4 is H, C 1-4 alkyl or Cl; R 6 is O or NH; and R 7 is 2-, 3- or 4-pyridyl (or their N-oxides), provided that (a) when R 6 is O, R 7 is pyridyl-N-oxide, and (b) when R 6 is NH, R 2 ... R 5 are each H and R 7 is pyridyl, R 1 is not Me. The imines are prepared by reacting the corresponding 3-unsubstituted indole (II) with 2-, 3- or 4-cyanopyridine or its N-oxide. The ketones are prepared by (i) forming the imine as just described, followed by hydrolysis; (ii) reacting II with a 2-, 3- or 4- pyridinecarboxylic acid dialkylamide (N-oxide) in presence of a Lewis Acid, and hydrolysing the complex so formed; (iii) reacting II-organo-Mg derivative with a 2-, 3- or 4-pyridinecarboxylic acid halide (N-oxide), and hydrolysing the complex so formed. Pharmaceutical and veterinary compositions for treating inflammation or combatting intravascular thrombosis comprise the above compounds (but the proviso does not apply), and may be administered orally, parenterally, rectally or topically.
[GB1318300A]
Patent IE-34024-L (IE)
Title: Pipe joints
IPC: E02B11/00
Filed: 1969-10-30
Abstract: The invention relates to a tubular connecting piece for grooved tubes whereby one or more ends of the piece are at least partially closed by two end planes making an angle with respect to one another. Each end plane covers at least a part of the half section of one end of the connecting piece. The end edges of the end planes are connected by planes extending parallel to the longitudinal direction of the part of the connecting piece comprising said end planes.
[US3652109A]
Patent IE-821866-L (IE)
Title: Control system for a pneumatic therapeutic apparatus
IPC: A61H15/00
Filed: 1982-08-03
Abstract: A pneumatic control system for a dynamic pressure wave device connects a source of pressurized gas to the first chamber of the appliance. When the pressure in the first chamber reaches a first predetermined level, a valve seals the first chamber and connects the source so as to inflate a second chamber about the first. When the pressure in the second chamber reaches a second predetermined level, a valve permits the first chamber to deflate while continuing to connect the second chamber for inflation. A seal for the inflated sleeve discontinues the inflation of the sleeve when the pressure therein reaches a third predetermined level. The sequence of operation of the pneumatic control circuit will cause a suitable dynamic pressure wave appliance to apply a pressure to a human or animal extremity which begins at the most distant end and travels up the extremity in the nature of a pressure wave.
[CA1178500A]
Patent IE-811889-L (IE)
Title: Container carrier pack
IPC: B65D71/46
Filed: 1981-08-18
Abstract: The invention provides a holding device for one or more rows of bottles or the like. The device comprises essentially a sleeve of sheet material having upper and lower walls and side walls, and the device is applied to the containers by passing it over the containers so that the tops pass through apertures in the base wall and then apertures in the top wall. The containers are locked to the device by virtue of the device having locking tabs or a locking wall which folds upwardly by virtue of engagement with the containers, but locks under the container rims or beads on the caps of the containers or at the container mouths, preventing removal of the container by movement in an opposite direction. Preferably, there are two locking devices which engage the container rims or beads at opposite sides, and lie in an inclined position relative to the container axis. The sleeve is preferably of rectangular or square cross section so that it can be displaced to flattened form about crease lines lying at a pair of opposite corners, for transportation.
[US4432579A]
Patent IE-892224-L (IE)
Title: Optical star couplers
IPC: G02B6/28
Filed: 1989-07-11
Abstract: An optical 1xN star coupler has a single mode input fibre I and N single mode output fibres O1 forming an output fibre assembly. The output fibres O are tapered within a former 2 which holds each output fibre O so it is positioned substantially identically relative to the remaining output fibres. The input fibre I is also tapered such that the fundamental mode field of the input fibre I and output fibre assembly are substantially equal. The identical relative positions of the output fibres O provides a wavelength independent 1xN star coupler.