baber/WOPTO huggingface dataset:
Patent EA-006238-B1 (EA)
Title: 2-(3,5-BIS-TRIFLUOROMETHYL-PHENYL)-N-[0-(1,1-DIOXO-1λ6-THIOMORPHOLIN-4-YL)-4-(2-METHYL OR 4-FLUORO-2-METHYL SUBSTITUTED)PHENYL-PYRIDIN-3-YL]-N-METHYL-ISOBUTYRAMIDE
Inventor: BALLARD THERESA MARIA
IPC: C07D213/75
Filed: 2002-07-26
Abstract: The invention relates to the compounds 2-(3,5-bis-trifluoromethyl-phenyl)-N-[6-(1,1-dioxo-1λ<6>-thiomorpholin-4-yl)-4-o-tolyl-pyridin-3-yl]-N-methyl-isobutyramide and 2-(3,5-bis-trifluoromethyl-phenyl)-N-[6-(1,1-dioxo-1λ<6>-thiomorpholin-4-yl)-4-(4-fluoro-2-methyl-phenyl)-pyridin-3-yl]-N-methyl-isobutyramide, which may be used for the treatment of migraine, rheumatoid arthritis, asthma, bronchial hyperreactivity, inflammatory bowel disease or for the treatment of disorders including Parkinson's disease, anxiety, depression, pain, headache, Alzheimer's disease, multiple sclerosis, oedema, allergic rhinitis, Crohn's disease, ocular injury, ocular inflammatory diseases, psychosis, motion sickness, induced vomiting, emesis, urinary incontinence, psychoimmunologic or psychosomatic disorders, cancer, withdrawal symptoms of addictive drugs from opiates or nicotine, traumatic brain injury or benign prostatic hyperplasia.
Patent EA-008947-B1 (EA)
Title: PRARα AGONISTS AND USE THEREOF
Inventor: BHUNIYA DEBNATH
IPC: C07C303/30
Filed: 2002-12-02
Abstract: The present invention relates to novel antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds, which are predominantly PPAR alpha agonists, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. The present invention also relates to processes for the preparation thereof and use thereof as antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds.
Patent EA-006707-B1 (EA)
Title: Sulfonyl-derivatives as novel inhibitors of histone deacetylase
Inventor: VAN EMELEN KRISTOF
IPC: C07D243/08
Filed: 2003-03-11
Abstract: This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Patent EA-006496-B1 (EA)
Title: Device for changing nozzles
Inventor: HOLTING LUDWIG
IPC: B01J19/26
Filed: 2003-03-15
Abstract: The invention relates to a device which enables nozzles to be changed without changing the pressure conditions in the container or device associated therewith. According to the invention a connector piece support (2) is fixed to a pressurised container (1) wherein a medium (20) is guided into said container through a nozzle (8) by means of a lance (7). Said connector piece is connected to a sealing housing (5) by means of a locking device (3) in order to receive the lance (7). Sealing rings (13a, 13b, 13c) are arranged in the sealing housing (5) thereby ensuring pressure-tightness in relation to the container (1) and the surrounding area when the lance (7) is inserted into the sealing housing (5).
Patent EA-008604-B1 (EA)
Title: Expanded polystyrene bead having functional skin layer, manufacturing process thereof, and functional eps product and manufacturing process thereof using the same
Inventor: PARK BONG-KUK
IPC: C08J9/224
Filed: 2004-01-30
Abstract: Disclosed herein are expanded polystyrene particles having a polyvinyl acetate resin-based functional skin layer formed on the surface of expanded polystyrene particles. Further disclosed are a process for producing the expanded polystyrene particles and the use of the expanded polystyrene particles. According to the expanded polystyrene particles of the present invention, inherent properties of the expanded polystyrene, e.g., light weight, thermal insulation properties, shape stability, buffering properties and sound absorption, are ensured, and superior low-temperature bonding properties, air-tightness, waterproofness and durability are provided by the vinyl acetate based polymer constituting the skin layer. Optionally, various functional additives, including flame retardants, water repellents, antibacterial agents, colorants, flavoring agents, etc., can be added to the polyvinyl acetate resin to impart a variety of functions to the expanded polystyrene particles in a simple manner.
Patent EA-010791-B1 (EA)
Title: A method for dissolving oilfield scale
Inventor: KEATCH RICHARD
IPC: B08B3/04
Filed: 2007-03-23
Abstract: A method of removing metal scale from surfaces that includes contacting the surfaces with a first aqueous solution of a chelating agent, allowing the chelating agent to dissolve the metal scale, acidifying the solution to form a precipitant of the chelating agent and a precipitant of the metal from the metal scale, isolating the precipitant of the chelating agent and the precipitant of the metal from the first solution, selectively dissolving the precipitated chelating agent in a second aqueous solution, and removing the precipitated metal from the second solution is disclosed.
Patent EA-011743-B1 (EA)
Title: Oil-based sludge separation and treatment system
Inventor: IVAN CATALIN
IPC: C02F11/12
Filed: 2006-05-19
Abstract: An apparatus for treating oil-based sludge includes a boiler, a heat exchanger having a circulatory steam path in fluid communication with the boiler and a sludge path receiving sludge, a plurality of serially- aligned mixers in fluid communication with the sludge path of the heat exchanger, a separation tank in fluid communication with the plurality of mixers, and wherein the separation tank includes a tank having a plurality of walls, a hydrocyclone mounted within the tank receiving sludge from the plurality of mixers, wherein the hydrocyclone includes a solids outlet directing a solids component towards a bottom portion of the tank and a fluid outlet directing a fluid component into the tank, a means for conveying separated solids along the bottom portion of the tank to a solids outlet, and a plurality of fluid outlets vertically located along a tank wall, wherein each outlet includes a valve providing selective fluid communication from the tank.
Patent EA-014427-B1 (EA)
Title: Bicyclic cinnamide compound
Inventor: KIMURA TEIJI
IPC: C07D471/04
Filed: 2006-11-01
Abstract: A bicyclic cinnamide compound represented by the formula (I):whereinindicates a single bond or double bond; Arrepresents phenyl or pyridinyl optionally substituted by one to three substituents; Rand Reach represents C1-6 alkyl, hydroxy, etc.; Zrepresents optionally substituted methylene or vinylene, oxygen, or imino optionally substituted by C1-6 alkyl or C1-6 acyl; and p, q, and r each is an integer of 0-2. It functions to reduce the production of Aβ40 and Aβ42. It is hence useful especially as a preventive or remedy for neurodegenerative diseases of which Aβ is causative, such as Alzheimer's disease and Down's syndrome.
Patent EA-016044-B1 (EA)
Title: Derivatives of 5-thioxilopyranose
Inventor: BARBEROUSSE VERONIQUE
IPC: A61K31/70
Filed: 2007-09-26
Abstract: The invention relates to new compounds of 5-thioxilose, preferably derivatives of the 5-thioxilopyranose type, formula (I)and to a method for preparing the same and their use as the active ingredient of drugs mainly intended for treating or preventing thrombosis or heart failure or thromboembolic diseases.
Patent EA-018260-B1 (EA)
Title: Antibodies to human delta-like ligand 4 (dll4) and use thereof
Inventor: GURNEY AUSTIN
IPC: C07H21/04
Filed: 2007-09-28
Abstract: An isolated antibody that specifically binds to an extracellular domain of human DLL4 and affects growth of a tumor comprising cancer stem cells is described. Also described is a method of treating cancer comprising administering a therapeutically effective amount of an anti-DLL4 antibody.
Patent EA-020710-B1 (EA)
Title: PYRIDAZINE DERIVATIVES AS Smo INHIBITORS
Inventor: HE FENG
IPC: C07D471/04
Filed: 2009-07-16
Abstract: The present invention relates generally to novel compounds relating to the diagnosis and treatment of pathologies relating to the Hedgehog pathway, including but not limited to tumor formation, cancer, neoplasia, and non-malignant hyperproliferative disorders. The present invention includes novel compounds, novel compositions, methods of their use and methods of their manufacture, where such compounds are generally pharmacologically useful as agents in therapies whose mechanism of action involve methods of inhibiting tumorigenesis, tumor growth and tumor survival using agents that inhibit the Hedgehog and Smo signaling pathway.
Patent EA-020731-B1 (EA)
Title: Amino azaheterocyclic carboxamides
Inventor: SUTTON AMANDA E
IPC: C07D409/12
Filed: 2010-02-04
Abstract: The invention provides novel substituted amino azaheterocyclic carboxamide compounds according to Formula (II)their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.
Patent EA-023449-B1 (EA)
Title: Method of preparing phytocomposition
Inventor: BASHILOV ANTON VYACHESLAVOVICH
IPC: A23F3/34
Filed: 2013-02-26
Abstract: The invention relates to food industry and deals with method of production of phytocompositions. A phytocomposition contains meadowsweet inflorescences, peppermint herb and Dasiphora fruticosa herb in weight ratio 1:1:1. The phytocomposition is prepared by mixing of preliminarily dried and milled vegetable components in required weight ratio. Brewing is realised just before intake. 1/3-2/3 tea s. of herbal mixture is poured with 150 ml of water (temperature 85-95°C) and infused for 5-10 min. The phytocomposition, like ordinary tea, has tonic activity, as well as possesses antioxidant, anti-inflammatory and antiulcerogenic effects due to impact of constituent components.
Patent EA-026360-B1 (EA)
Title: Cd33 binding agents
Inventor: KONOPITZKY RENATE
IPC: C07K16/28
Filed: 2011-10-04
Abstract: The present invention describes immunotherapies that are based on myeloid cell depletion. In particular, the present invention describes CD33 binding agents for use in such therapies, e.g. in the treatment of myeloid cell malignancies and myelodysplastic syndrome (MDS).
Patent EA-022621-B1 (EA)
Title: Aqueous slurry of amorphous silica and method for its production
Inventor: AL-BAGOURY MOHAMED
IPC: C04B14/06
Filed: 2011-05-16
Abstract: An aqueous slurry of amorphous silica, the amorphous silica having a particle size less than 1 μm. The slurry contains sepiolite as a stabiliser.
Patent EA-029949-B1 (EA)
Title: Drying chamber, drying unit, dryer of recycled abrasive and method of drying wet recycled abrasive
Inventor: MESTANEK JIRI
IPC: F26B17/26
Filed: 2016-06-23
Abstract: Provided is drying of a recycled abrasive, which can be recycled separately or as a part of a full recycling system. The sorted and sifted wet recycled abrasive is placed in a reservoir for a wet recycled abrasive, the snail conveyor continuously feeds it to a drying chamber with a vibrating screen. An air current generator is used to blow air into the chamber, under the vibrating screen. Using the air flow and vibration of the screen, the recycled abrasive is moved and tossed on the screen, hence the lumps of the recycled abrasive are broken into single recycled abrasive particles, and the abrasive is mixed and dried.
Patent EA-029994-B1 (EA)
Title: Graphite-based carbon material useful as graphene precursor and method for producing same
Inventor: HASEGAWA SHOJI
Filed: 2015-02-27
Abstract: Provided is a graphite-based carbon material useful as a graphene precursor, from which graphene is easily exfoliated when the graphite-based carbon material is useful as a precursor and from which a highly-concentrated graphene dispersion can easily be obtained. The graphite-based carbon material is a graphite-based carbon material useful as a graphene precursor wherein a Rate (3R) based on an X-ray diffraction method, which is defined by following Equation 1 is 31% or more: Rate (3R)=P3/(P3+P4)×100 (Equation 1), wherein P3 is a peak intensity of a (101) plane of the rhombohedral graphite layer (3R) based on the X-ray diffraction method, and P4 is a peak intensity of a (101) plane of the hexagonal graphite layer (2H) based on the X-ray diffraction method.
Patent EA-035311-B1 (EA)
Title: Method of tagging dna-encoded chemical libraries
Inventor: WAGNER RICHARD W
IPC: C40B20/04
Filed: 2010-02-16
Abstract: The present invention relates to a method of tagging DNA-encoded chemical libraries. The method comprises binding a first functional group of a bifunctional linker to a headpiece comprising an initiator oligonucleotide, wherein said initiator oligonucleotide comprises a hairpin structure; binding a second functional group of the bifunctional linker to a first building block; reacting a second building block with said first building block in an organic solvent; and binding an identifier region at the 3' end of said headpiece, wherein the identifier region encodes said second building block. The method provides a step-wise approach to screening and identifying small molecules that have greater potency.
Patent EA-032916-B1 (EA)
Title: Air conditioning unit for a pneumatic system of a rail car
Inventor: KUDRYAVITSKY MIKHAIL ALEXANDROVICH
IPC: B60T17/02
Filed: 2018-09-18
Abstract: The invention relates to devices for preparation of purified, compressed and dried air intended for use by various consumers in a pneumatic system of a rail car. The air conditioning unit for a rail car pneumatic system is structurally based on a combination of a double-stage piston oil-free compressor (23) and a compressed air drying unit (33) that is based on a membrane dryer (46). In order to eliminate cyclic stretching and compression of hollow polymer fibers of the membrane dryer (46) during intermittent changes of compressed air pressure in the pneumatic system due to the oil-free compressor (23) operation, by way of ensuring constant compressed air pressure in the membrane dryer (46) and preventing contamination of the membrane (50) hollow polymer fibers by solid particles, the unit further comprises a second electromagnetic valve (57), a second air filter (58) and a check-valve (59) pneumatically connected in series.
Patent EA-034271-B1 (EA)
Title: Sealing valve arrangement for a shaft furnace charging installation
Inventor: HUTMACHER PATRICK
IPC: F27D99/00
Filed: 2016-09-06
Abstract: A sealing valve arrangement for a shaft furnace charging installation, said arrangement comprising a shutter arranged for cooperating with a valve seat; an integrated dual-motion shutter-actuating device for moving said shutter between a sealed closed position in sealing contact with the valve seat and an open position remote from the valve seat, said integrated dual-motion shutter-actuating device comprising a primary motion assembly for moving said shutter from said sealed closed position to an undamped position wherein the shutter is released from the valve seat; a secondary motion assembly for tilting said shutter from said undamped position to said open position remote from the valve seat, said secondary motion assembly comprising a tilting arm carrying said shutter and connected to a tilting shaft that defines an axis of rotation and a tilting shaft actuator configured to impart an angular rotation about said axis to said tilting arm; wherein said integrated dual-motion shutter-actuating device further comprises a stationary outer cylindrical sleeve, wherein said primary motion assembly comprises an inner eccentric sleeve shaft rotationally mounted within said outer cylindrical sleeve and a primary motion actuator configured to impart angular rotation to said inner eccentric sleeve shaft, the primary motion being a function of the eccentricity and angular rotation of the inner eccentric sleeve shaft; and wherein said tilting shaft of said secondary motion assembly is rotationally mounted within said inner eccentric sleeve shaft of said primary motion assembly, the secondary motion being a function of the angular rotation of the tilting shaft.
Patent EA-035339-B1 (EA)
Title: Beverage font for a beverage dispensing system, beverage dispensing system comprising a beverage font and method of dispensing a mixed alcoholic beverage product by providing a beverage dispensing system
Inventor: RASMUSSEN JAN NOERAGER
IPC: B67D1/00
Filed: 2016-12-07
Abstract: The present invention relates to a beverage font (10) for a beverage dispensing system. The beverage font (10) comprises a mixing conduit (24) having a first inlet (24A) for receiving a pressurized beverage defining a first alcoholic percentage and a second inlet (26) for receiving an additive defining a second alcoholic percentage. The mixing conduit (24) further has an outlet (18) for supplying a mixed alcoholic beverage product constituting a mixture of the beverage and the additive. The font (10) further comprises a control unit (38) for receiving a parameter representing a specific alcoholic percentage or a specific concentration of the additive relative to the mixed alcoholic beverage. The control unit (38) is capable of causing the additive to flow from the second inlet (26) to the mixing conduit for generating a flow of the mixed alcoholic beverage defining the specific alcoholic percentage or the specific concentration of the additive relative to the mixed alcoholic beverage through the outlet (18).
Patent EA-039372-B1 (EA)
Title: System of the hill start assist for a truck and a road train without rolling back
Inventor: LE VAN NGHIA
IPC: B60T8/17
Filed: 2018-11-02
Abstract: The invention relates to the field of transport machine building, in particular to the hill start assist system (SAS) for vehicles with no rolling back. Basis of the hardware platform of the hill start assist system developed is the ABS modulator (Anti-lock Braking System), which controls the pressure of compressed air in the working brake chamber upon maintaining the vehicle on a hill. The advantages of this vehicle hill start assist system the over the proposed well-known auto manufacturers are as follows: it does not require installation of additional complex elements or systems due to the use of components available on board the vehicle, which improves competitive capacity of the product; it allows to obtain a high quality process of the brake chamber pressure control and, consequently, the braking torque developed on wheels. At this time, the dynamic load of transmission elements reduces due to adjusting the transmission braking torque increase with the decrease in the braking torque developed on wheels. The invention allows to retrofit the automated mechatronic powertrain control system with a function of hill start assist by programming the ECU (electronic control unit) of ABS.
Patent ES-2199012-B1 (ES)
Title: Perfeccionamientos introducidos en la fabricacion de plantas para calzado.
Inventor: GARCIA DEL POZO LOPEZ BENIGNO
IPC: A43B7/08
Filed: 2001-02-28
Granted: 2005-06-01
Abstract: Perfeccionamientos introducidos en la fabricación de plantas para calzado. Se describe una planta para calzado sensiblemente perfeccionada, a la que se ha dotado de unas características incrementadas de comodidad de uso del calzado que la incorpora, y de aireación y ventilación del pie del usuario, en virtud de la flexibilidad total y completa que presenta la planta, y que permite que el calzado se adapte mejor a cualquier situación derivada de su uso. La planta fabricada según la invención consta de un cuerpo formado por dos capas (1, 2) íntimamente ligadas entre sí, ambas de material flexible, con múltiples orificios (4) pequeños de paso de aire, de las que la capa superior incorpora además ranuras (3) o pasos para el aire de ventilación. Dicha capa (2) superior admite la colocación sobre la misma de una lámina delgada (5), eventualmente dotada también de orificios (6).
Patent ES-2195723-B1 (ES)
Title: Manto recolector de aceituna y frutos similares caidos al suelo de forma natural.
Inventor: JIMENEZ ARROYO FELIX JESUS
IPC: A01D46/00
Filed: 2001-05-07
Granted: 2005-08-01
Abstract: Manto recolector de aceituna y frutos similares caídos al suelo de forma natural (1), resistente y reciclable, colocado en el suelo bajo la copa del árbol y envolviendo al tronco del mismo, constituido por dos mitades iguales y simétricas, que se cierran por solape en línea horizontal (6), conformando un taladro circular (2) lo suficientemente grande para alojar al tronco, de cuyo reborde parte verticalmente un fuelle (3) para el cierre completo de los huecos y facilitar el repliegue de manto sobre el árbol. Presenta también una serie de pequeños taladros (4) uniformemente distribuidos por la superficie para la evacuación del agua de lluvia, así como un refuerzo perimetral (5) para su fijación al terreno. El manto no precisa de mantenimiento en servicio, al ser reciclable, lo que supone un bajo coste para el fin a que se destina, con prácticamente nulo impacto medioambiental.
Patent ES-2188370-B1 (ES)
Inventor: GAVILLERO MARTIN JUAN MIGUEL
IPC: H04L7/00
Filed: 2001-05-21
Granted: 2004-10-16
Abstract: The invention relates to a system that is suitable for bidirectional communication via the electrical network between a headend and numerous users. Said invention can be used for both time and frequency synchronisation of multiple users in an OFDM (Orthogonal Frequency Division Multiplexing) multi-carrier communication system. The inventive method is characterised in that it consists in generating synchronisation sequences using two identical synchronisation symbols (16) which are transmitted periodically from the headend equipment by means of the downlink to the users. The sampling frequency can then be determined and corrected and, simultaneously, the moment at which the OFDM symbol starts can be determined, such that the samples of the signal received by each user match those used in the transmission. <IMAGE>
Patent ES-2192993-B1 (ES)
Title: Superficie con dispositivo hinchable.
Inventor: MARTINEZ ESPINO BARTOLOME
IPC: B42D15/04
Filed: 2002-03-13
Granted: 2005-02-16
Abstract: Superficie con dispositivo hinchable, empleado en cromos, postales, pósteres, páginas de cuentos, etc., constituido por una superficie-base (2) sobre la que está adherida un elemento hinchable (1), el cual dispone de un conducto (3) para la entrada de aire, presentando este un sistema de cierre (4).
Patent ES-2197828-B1 (ES)
Title: Modelos animales transgenicos en drosophila para las distrofias miotonicas.
Inventor: PEREZ ALONSO MANUEL
IPC: A01K67/027
Filed: 2002-06-18
Granted: 2005-04-01
Abstract: Modelos animales transgénicos en Drosophila para las distrofias miotónicas. La invención trata de la aplicación de un transgén que incluye, total o parcialmente, la secuencia génica muscleblind, de Drosophila o sus homólogas en humanos (por ejemplo, MBNL), a un modelo animal transgénico. Este modelo transgénico se ha obtenido mediante la integración estable del transgén en el genoma de Drosophila melanogaster. En dichos animales, el transgén se expresa fenotípicamente, de forma controlada, en cualquiera de sus estados de desarrollo. Los modelos animales de la invención son de aplicación en la investigación de los mecanismos de patogénesis responsables de las distrofias miotónicas, como dispositivos de ensayo de posibles compuestos terapéuticos para el tratamiento de dichas enfermedades y como dispositivos de validación in vivo de tratamientos potenciales de las mismas.