baber/WOPTO huggingface dataset:
Patent CA-3147354-A1 (CA)
Title: Siderophore cephalosporin conjugates and uses thereof
Inventor: RIEDL ROSEMARIE
IPC: A61P31/00
Filed: 2020-09-04
Abstract: A compound of compound according to formula (I), wherein X is selected from the group consisting of CH, CCl and N, Z is selected from the group consisting of CH<sub>2</sub>COOH, CH(CH<sub>3</sub>)COOH, C(CH<sub>3</sub>)<sub>2</sub>COOH and CH<sub>2</sub>F, D is a single bond connecting A and Ar or selected from the group consisting of CO, NHCO and N(C<sub>0-</sub>
<sub>6</sub>)alkyl-CO, A is selected from the group consisting of a (C<sub>1-6</sub>)alkanediyl and a (C<sub>3-</sub>
<sub>6</sub>)cycloalkanediyl or, if D is N(C<sub>0</sub>)alkyl-CO, A forms a 4- to 7-membered aliphatic heterocyclic ring with the nitrogen atom of N(C<sub>0</sub>)alkyl-CO in D, and Ar is a 6-membered aromatic ring with a first hydroxyl group in <i>para</i>-position to D, a second hydroxyl group in <i>meta</i>-position to D, and with at least one electron-withdrawing element and uses thereof.
Patent CA-3147477-A1 (CA)
Inventor: ROCHE ELLEN
IPC: A61B17/00
Filed: 2020-08-19
Abstract: L'invention concerne un implant médical (1) qui est conçu pour fermer un défaut (D) ou une cavité, de préférence un défaut dans une paroi auriculaire ou septale (W) ou un appendice auriculaire gauche. L'implant (1) comprend un dispositif d'occlusion (6) et présente deux états. Il est conçu pour, dans un premier état, être déployé sur un site de défaut (D), où il peut être amené dans un second état par un mécanisme d'activation. Il est conçu pour fermer ledit défaut (D) dans ledit second état.
Patent CA-3148027-A1 (CA)
Title: Cll-1 targeted immunotherapies
Inventor: JARJOUR JORDAN
IPC: A61K39/395
Filed: 2020-05-07
Abstract: The present disclosure provides improved CLL-1 targeting polypeptides and compositions for adoptive T cell therapies for treating, preventing, or ameliorating at least one symptom of a cancer, infectious disease, autoimmune disease, inflammatory disease, and immunodeficiency, or condition associated therewith.
Patent CA-3150796-A1 (CA)
Inventor: BURKETT ALAN DUNCAN
IPC: H05K5/02
Filed: 2019-09-10
Abstract: Déflecteur pouvant être configuré pour réduire l'entrée d'au moins l'un entre de la poussière ou un fluide dans un coffret configuré pour renfermer, à l'intérieur, une pluralité de connexions de communication optique. Le déflecteur peut comprendre une première patte définissant un premier bord d'intersection et un premier bord distant. La première patte peut définir un premier trou adjacent à la première extrémité de la première patte et un second trou adjacent à la seconde extrémité de la première patte. Le déflecteur peut également comprendre une seconde patte définissant un second bord d'intersection et un second bord distant. Les premier et second bords d'intersection peuvent être couplés l'un à l'autre pour définir un angle de déflecteur. Le premier trou peut être conçu pour recevoir une première tige de montage en relation avec le coffret et le second trou peut être conçu pour recevoir une seconde tige de montage en relation avec le coffret.
Patent CA-3150865-A1 (CA)
Title: Capteur non invasif permettant de determiner un battement cardiaque et/ou un rythme cardiaque dans un segment d'un circuit sanguin extracorporel
Inventor: ROVATTI PAOLO
IPC: A61M1/36
Filed: 2020-09-18
Abstract: L'invention concerne un capteur de battement cardiaque non invasif permettant de déterminer un rythme cardiaque dans un conduit d'un appareil de traitement sanguin extracorporel, comprenant une source permettant de diriger un signal optique vers le sang s'écoulant dans le segment ; un détecteur permettant de recevoir un signal d'information optique comprenant le signal émis par ladite source après passage du sang, et d'émettre un signal de sortie respectif ; un dispositif de commande recevant le signal de sortie respectif et récupérant une fréquence de battement cardiaque et une valeur de rythme cardiaque, en fonction du signal de sortie, le signal d'information étant modifié par une perturbation d'écoulement du sang partiellement généré par les impulsions d'écoulement provenant du c?ur.
Patent CA-3153027-A1 (CA)
Inventor: KAZANBAS MEHMET CEMIL
IPC: G06F13/00
Filed: 2020-08-24
Abstract: The present invention comprises at least one processing unit (2) which is provided in air and/or space vehicles and enables the avionic systems of air and/or space vehicles to be controlled and managed, at least one sensing unit (3) which enables the data used in the execution of the flight control algorithm to be received from the physical environment, at least one application unit (4) which enables the instructions transmitted by the processing unit (2) to be performed, at least one programmable hardware unit (5) which is provided in association with the sensing unit (3) and the application unit (4), and enables the data received from the sensing unit (3) to be processed and enables the air vehicle control instructions to be transmitted to the application unit (4), and at least one volatile memory unit (6) which is provided in association with the processing unit (2), is capable of exchanging data with the processing unit (2), and enables the data processed by the processing unit (2) to be stored.
Patent CA-3154755-A1 (CA)
Inventor: RAPOPORT URI
IPC: G01R33/38
Filed: 2017-03-26
Abstract: A magnetic field device, with a first magnet, a first ferromagnetic element positioned adjacent to the first magnet, a second magnet, a second ferromagnetic element positioned adjacent to the second magnet and relative to the first ferromagnetic element to create a gap between the first ferromagnetic element and the second ferromagnetic element, and a third magnet positioned between the first ferromagnetic element and the second ferromagnetic element and within the gap.
Patent CA-3156468-A1 (CA)
Title: Method and equipment for the continuous cleaning of a moving steel strip
Inventor: RICHET PIERRE
IPC: C23G1/00
Filed: 2019-11-05
Abstract: The invention concerns a continuous cleaning installation 1 of a passing strip S comprises a tank 2, an aqueous solution 3 inside said tank 2. It also comprises at least a roll 4 immerged in said aqueous solution 3, at least an ultrasound emitting mean 5, means for feeding 6 an aqueous solution and emptying 7 the tank. Moreover, it also comprises means for estimating 8 the aqueous solution level, means for calculating 9 for each ultrasound emitting mean 5 its distance to the aqueous solution level and means for controlling the power 10 of the at least one ultrasound emitting mean 5 and at least an impermeable closable opening 11 on at least a lateral side of said tank through which the at least one ultrasound emitting mean 5 can pass.
Patent CA-3158506-A1 (CA)
Inventor: SHAH BHAVIT
IPC: H04L45/74
Filed: 2020-09-21
Abstract: A system comprises a gateway computer further comprising a processor and a memory. The memory stores instructions executable by the processor to determine one or more service functions (SF) based on a received data packet, and to determine a list of routing identifiers based on the determined service functions and a destination of the data packet. Each routing identifier identifies at least one of a router computer and a service function. The memory stores instructions to update the data packet to include the list of routing identifiers, and to transmit the updated data packet based on the list of routing identifiers.
Patent CA-3158688-A1 (CA)
Title: A system having at least two cryogenic containers for providing a fluid
Inventor: REBERNIK MATTHIAS
IPC: F17C7/02
Filed: 2020-09-23
Abstract: The invention relates to a system (1) for providing a fluid, comprising at least a first and a second cryogenic container (7, 8) for storing the fluid, wherein the system (1) comprises a first retrieval line (11) connecting to the first cryogenic container (7) for retrieving a first mass flow (M1) of fluid and a second retrieval line (12) connecting to the second cryogenic container (8) for retrieving a second mass flow (M2) of fluid, wherein the system (1) comprises means (13), which are configured to establish two mass flows (M1, M2) of different dimensions such that in a first operational mode a hold time of the two cryogenic containers (7, 8) converges upon retrieval and/or in a second operational mode the hold time of the two cryogenic containers (7, 8) essentially decreases at the same rate if the hold times of the two cryogenic containers (7, 8) are essentially equal.
Patent CA-3163040-A1 (CA)
Title: Method and apparatus for reducing body stress typically experienced by a snowboarder while on a chairlift
Inventor: GOLDENRING IRA
IPC: A63C10/16
Filed: 2020-12-11
Abstract: A Method and apparatus for reducing stress on the body (e.g., foot, ankle, hip, spine) of a snowboarder while sitting on a chairlift. The apparatus includes a boot binding assembly adapted for mounting on the top surface of a snowboard including a boot retention member hinged for movement between a dosed position and an open position. For typical downhill snowboarding activity, a user will place the retention member in the closed position to orient the sole of the user's boot substantially parallel, i.e. against the snowboard top surface. For sitting on a chairlift, the user will place the retention member in the open position so as to allow the snowboard to pivot around the hinge and hang substantially vertically from the retention member thus avoiding stressful torques on the user's supporting limb.
Patent CA-3168320-A1 (CA)
Inventor: KRAUTHAMER AKIVA MEIR
IPC: A63G31/00
Filed: 2021-03-01
Abstract: An attraction system includes a sensor configured to emit an output signal toward a guest area and receive a reflected signal from the guest area and a control system communicatively coupled to the sensor. The control system is configured to receive data from the sensor, in which the data is indicative of a distance of signal travel based on the output signal and the reflected signal. The control system is also configured to compare the distance of signal travel with an unoccupied distance value corresponding to a distance between the sensor and the guest area being unoccupied, and determine whether the guest area is occupied based on comparing a difference between the distance of signal travel and the unoccupied distance value with a threshold.
Patent CA-3168541-A1 (CA)
Title: Aerosol-generating article including substrate with gel composition
Inventor: D'AMBRA GIANPAOLO
IPC: A24D1/18
Filed: 2021-02-24
Abstract: There is provided an aerosol-generating article (10) for producing an inhalable aerosol upon heating, the aerosol-generating article (10) comprising: a rod (12) of aerosol-generating substrate comprising a gel composition, the gel composition comprising at least one gelling agent, at least one of an alkaloid compound and a cannabinoid compound and an aerosol former; a mouthpiece element (42); and an intermediate hollow section (50) between the rod of aerosol- generating substrate and the mouthpiece element. The intermediate hollow section (50) comprises an aerosol-cooling element (24) in axial alignment with the mouthpiece element and abutting the upstream end of the mouthpiece element (42), the aerosol-cooling element (24) comprising a hollow tubular segment (34) having a length of less than 10 millimetres and defining a longitudinal cavity providing an unrestricted flow channel, wherein the flow channel is substantially empty. The intermediate hollow section (50) further comprises a support element (22) downstream of the rod (12) of aerosol-generating substrate, the support element comprising a hollow tubular segment (26) defining a longitudinal cavity (28) providing an unrestricted flow channel, the hollow tubular segment (26) having a wall thickness of at least 1 millimetre.
Patent CA-3171214-A1 (CA)
Title: Machine walls
Inventor: MAY JOSHUA
IPC: E04B1/21
Filed: 2021-04-08
Abstract: Improvements in machine walls to construct a building or house. Adjacent side of the wall sections are tapered and dovetailed that lock-in-place. The dovetails are spaced to reduce the height that one section must be lifted to engage in an adjoining wall section. The footers / base plate will also have integrated earthquake or hurricane hold-downs in the footer / base plate that aligns and can be secured from the foundation to the wall sections. The connection of the wall section to the foundation to have counter flashing at the concrete insert and the wall-to-wall sections can be self-flashed. The wall sections can have GPS locators for positioning the wall sections. Plumbing and electrical conduit creating circuits that can be integrated into the walls and are connected sealed or bonded together.
Patent CA-3172443-A1 (CA)
Title: Peptides et proteines de synthese destines a la detection, a la prevention et au traitement d'une maladie a coronavirus 2019 (covid-19)
Inventor: WANG CHANG YI
IPC: A61P11/00
Filed: 2021-02-19
Abstract: La présente invention concerne un système de soulagement pour la détection, la prévention et le traitement efficaces de la COVID-19, comprenant (1) des dosages diagnostiques sérologiques pour la détection d'une infection virale et la surveillance épidémiologique, (2) des constructions immunogènes peptidiques dirigées sur site de haute précision pour la prévention d'une infection par le SARS-CoV-2, (3) des thérapies antivirales à base de récepteur pour le traitement de la maladie chez des patients infectés, et (4) un vaccin à base de protéine sur mesure contenant S1-RBD-sFc. Le système de soulagement selon l'invention utilise des séquences d'acides aminés provenant de protéines du SARS-CoV-2 ainsi que des récepteurs humains pour la conception et la fabrication de peptides antigéniques du SARS-CoV-2 optimaux, de constructions immunogènes peptidiques, de constructions immunogènes de protéines dérivées de CHO, de protéines ACE2 dérivées de CHO à action prolongée, et de formulations de ceux-ci, en tant que diagnostics, vaccins et thérapies antivirales pour la détection, la prévention et le traitement de la COVID-19.
Patent CA-3176769-A1 (CA)
Title: Device for joining, and discharging the leakage currents from, two shroud portions for containing a pressurised gas
Inventor: CHARON ROMAIN
IPC: H02G5/06
Filed: 2021-03-24
Abstract: The invention relates to a device for joining, and discharging the leakage currents from, two shroud portions for containing a pressurised gas, comprising a substantially U-shaped electrical connector for forming a shunt between a first and a second clamp. According to the invention, the inner faces of the flanges of the electrical connector each have a groove configured to house a sealing element for bearing on the first clamp or on the second clamp and the device comprises a first and a second sealing cap comprising a housing suitable for receiving the end of a screw for joining the clamps which are designed to be mounted so as to form a seal bearing against the faces of the side flanges of the electrical connector.
Patent CA-3177632-A1 (CA)
Title: Methods and compositions for treating anemia using actriib ligand traps and mtor inhibitors
Inventor: ACAR MELIH
IPC: A61K39/395
Filed: 2021-05-14
Abstract: Provided herein are methods of treating anemia or for enhancing late stage erythropoiesis in a subject comprising administering to the subject an activin type IIB (ActRIIB) ligand trap and an mTOR inhibitor.
Patent CA-3177675-A1 (CA)
Title: Knitted loops for masks or garments
Inventor: LEONARD MICHAEL
IPC: A41D27/22
Filed: 2021-05-07
Abstract: In one aspect, a knitted loop for a mask or garment is formed by a process including providing a yarn, knitting the yarn to form an individual loop, cutting the individual loop to form two ends, and attaching at least one end of the two ends to a garment. In another aspect, a knitted loop for a mask or garment is formed by a process including providing a yarn, knitting the yarn to form a fabric tube, cutting the fabric tube into at least one individual loop, and attaching the at least one individual loop to a garment.
Patent CA-3177976-A1 (CA)
Inventor: GUNDRY ADIA
IPC: B65H75/48
Filed: 2022-09-30
Abstract: Described is a strap-retraction slowing mechanism. Also described is a changing table comprising a retractable security strap. Described also is a diaper-changing table comprising a security strap for securing a child to the changing table, a cavity for storing the security strap when it is in a retracted position; and a strap-retraction slowing mechanism that allows the security strap to retract back into the cavity slower than it extends out from the cavity.
Patent CA-3178272-A1 (CA)
Title: Plate-forme de culture pour cultiver des tissus et procede d'observation des tissus qui y sont cultives
Inventor: HOFEMEIER ARNE
IPC: C12M1/32
Filed: 2021-05-17
Abstract: Dans divers modes de réalisation, l'invention concerne une plate-forme de culture pour cultiver des tissus, comprenant les éléments suivants : un premier composant (2) comprenant au moins une chambre de culture (21) formée en son sein, la chambre de culture (21) comprenant un fond (23), une paroi latérale et une partie supérieure ouverte (22) ; et un second composant (2) comprenant une base (31) et au moins une paire de montants (32) s'étendant à partir de la base (31), le premier composant (2) et le second composant (3) étant dimensionnés et configurés pour être accouplés l'une à l'autre de telle sorte que, lorsque le second composant (3) est placé sur le premier composant (2), la ou les paires de montants (32) sont insérées dans la ou les chambres de culture (21). En outre, l'invention concerne un procédé d'observation des tissus qui y sont cultivés.
Patent CA-3181827-A1 (CA)
Title: Polytherapie antitumorale comprenant un anticorps anti-cd19 et des polypeptides bloquant le point de controle immunitaire inne sirp?-cd47
Inventor: ENDELL JAN
IPC: A61P35/02
Filed: 2021-06-22
Abstract: La présente invention concerne une polythérapie comprenant un anticorps ou un fragment d'anticorps spécifique de CD19 et un polypeptide qui bloque le point de contrôle immunitaire inné SIRP?-CD47 pour une utilisation dans le traitement d'un cancer, en particulier d'un cancer hématologique tel qu'une leucémie ou un lymphome.
Patent CA-3181906-A1 (CA)
Inventor: GIREESHA BENAKA
IPC: E05B65/00
Filed: 2022-10-21
Abstract: An example lockset generally includes a housing, a bolt, a turnhub, and a spindle. The bolt is mounted in the housing for movement between an extended position and a retracted position. The tumhub is rotatably mounted in the housing and engaged with the bolt. Rotation of the tumhub in a bolt-extending direction drives the bolt toward the extended position, and rotation of the turnhub in a bolt-retracting direction opposite the bolt-extending direction drives the bolt toward the retracted position. The spindle engaged with the tumhub, is operable to exert torque on the turnhub in the bolt-retracting direction, and is selectively operable to exert torque on the turnhub in the bolt-extending direction. The housing includes a pair of stops configured to limit rotation of the spindle to a predetermined angular range.
Patent CA-3183510-A1 (CA)
Title: Method and system for controlling aircraft
Inventor: KRECK MARTIN
IPC: G01C21/00
Filed: 2021-07-01
Abstract: The invention relates to a method for controlling aircraft (17). A specified flight position of the aircraft (17) is compared with a piece of geographical height information (30, 31) corresponding to the provided flight position. The piece of geographical height information is obtained from a set (28, 29) of pieces of height information (30, 31), said set corresponding to a geographical area (35), wherein for a first part (45) of the geographical area (35), the set (28, 29) of pieces of height information (30, 31) indicates a piece of relevant geographical height information (30) and for a second part of the geographical area (35), the set indicates a piece of height information (31) deviating from the actual geographical height. The second part of the geographical area (35) comprises a first special area (32), in which the aircraft (17) is only permitted to operate to a limited degree. The height information (31) deviating from the actual geographical height is evaluated in order to actuate an operating component (22, 24, 51) of the aircraft (17) such that the aircraft (17) complies with the limitation when the aircraft (17) is operated in the first special area (32). The invention additionally relates to a corresponding control system.
Patent CA-3184503-A1 (CA)
Inventor: MAIER STEFAN KARL
IPC: C08G63/42
Filed: 2021-07-01
Abstract: The present invention is directed to polyesters, a method for their preparation and their use as high viscosity base fluids. It is further directed to lubricant compositions comprising such polyesters and to the use of such compositions as automatic transmission fluids, manual transmission fluids, continuously variable transmission fluids, gear oil formulations, industrial gear oil formulations, axle fluid formulations, dual clutch transmission fluids, dedicated hybrid transmission fluids or as hydraulic oils.
Patent CA-3185553-A1 (CA)
Inventor: LUX ANDREAS
IPC: B65B1/04
Filed: 2022-12-21
Abstract: The invention relates to a capsule filling machine for filling two-piece capsules that each comprise a capsule upper part and a capsule lower part.                          The capsule filling machine comprises a measuring device (22), the measuring device (22) comprising a capacitive measuring system (23).                                                  The measuring device (22) is downstream of the closing station (18). The capacitive measuring system (23) comprises a measuring section (25), along which the mass of the filled, closed capsule (8) can be measured by means of the capacitive measuring system (23).                                                         The measuring device (23) comprises a guide device (26) for the closed capsule (40), the guide device (26) being designed to convey the filled, closed capsule (8) from the capsule segment (5) to the measuring section (25) of the capacitive measuring system (23).
Patent CA-3186295-A1 (CA)
Title: Medicament a base de camptothecine ayant une unite de liaison hydrophile a stabilite elevee et conjugue de celui-ci
Inventor: ZHU YI
IPC: A61K47/50
Filed: 2021-05-31
Abstract: L'invention porte sur un médicament à base de camptothécine ayant une unité de liaison hydrophile à stabilité élevée, et sur un conjugué ou sur un sel pharmaceutiquement acceptable de celui-ci, et sur son procédé de préparation, ainsi que sur une application de celui-ci dans la prévention ou le traitement du cancer. Le conjugué peut se lier spécifiquement à un récepteur hautement exprimé dans des cellules tumorales. Le médicament à base de camptothécine présente une bonne solubilité dans l'eau, une bonne stabilité et une bonne uniformité et peut être utilisé pour prévenir ou traiter des maladies telles que des tumeurs.