baber/WOPTO huggingface dataset:
Patent NZ-502947-A (NZ)
Title: Compounds for modulating endogenous growth hormone
Inventor: TRANKLE WILLIAM GEORGE
IPC: C07K5/062
Filed: 1998-08-19
Abstract: Compounds of formula I wherein: A is C1-C6alkyl, aryl, C1-C6alkylaryl, C1-C6alkyl(O)C1-C6alkylaryl, C1-C6alkyl(S)C1-C6alkylaryl, indolyl, indolinyl, thienyl, (C1-C6alkyl)thienyl, benzothienyl, benzofuranyl, naphthanyl, cyclohexyl, (C1-C6alkyl)indolyl, (C1-C6alkyl)benzothienyl, (C1-C6alkyl)naphthanyl, (C1-C6alkyl)benzofuranyl, and (C1-C6alkyl)cyclohexyl;  B is NH2, NHR1, C1-C6alkylNH2, C1-C6alkylNHR1, C1-C6alkylarylNH2, C1-C6alkylarylNHR1, C1-C6alkylcyclohexylNH2, C1-C6alkylcyclohexyl- NHR1, R1-piperidin-3-yl(C1-C6alkyl), R1-piperidin-2-yl(C1-C6alkyl), R1-piperidin-4-yl(C1-C6alkyl), R1-quinolin-2-yl(C1-C6alkyl), R1-(2,4-dihydroquinolin-2-yl(C1-C6alkyl), R1-isoquinolin-2-yl(C1-C6alkyl), and R1-(2,4-dihydroisoquinolin-2-yl(C1-C6alkyl); R1 is hydrogen, C1-C6alkyl, C1-C6alkyl(OH), or C1-C6 alkylidenyl(OH)R2;  R2 is C1-C6alkyl, C1-C6alkenyl, C1-C6alkyl(O)C1-C6 alkyl, C(O)O-C1-C6 alkyl, aryl, or C1-C6alkylaryl; X is C1-C6alkylidenyl, O, S, NH, or N(C1-C6alkyl); V is selected from the group of formula listed; W is S, O, NH, or CH2;  Y, Z, Y' and Z' are N or CH;  E is hydrogen, C1-C6alkyl, C(O)C1-C6alkyl, aryl, (aryl)C(O)NR6, (aryl)(C1-C6alkylC(O)R6, C1-C6alkylaryl, C(O)aryl, C1-C6 alkylC(O)aryl, naphthyl, C1-C6alkylnaphthyl, C(O)naphthyl, C1-C6alkylC(O)naphthyl, heteroaryl, C1-C6alkylheteroaryl, C(O)heteroaryl, and C1-C6 alkylC(O)heteroaryl, indanyl, C1-C6alkylindanyl, C(O)indanyl, C1-C6alkylC(O)indanyl, cycloalkyl; G is hydrogen, C1-C6alkyl, aryl, C1-C6 alkylaryl, and C1-C6alkenyl; J is hydrogen, C1-C6alkyl, aryl, and C1-C6 alkylaryl; L is hydrogen, C1-C6alkyl, C(O)OC1-C6alkyl, aryl, C1-C6 alkylaryl, C(O)OC1-C6alkylaryl, C1-C6alkenyl, -F, and -CN, C1-C6alkyl-OH, C1-C6alkyl-O-C1-C6alkyl, C1-C6alkyl-C(O)R6; R4, R5, R6, R7 and D are defined in the specification; or a pharmaceutically acceptable salt or solvate thereof. The compounds are act to increase the level of endogenous growth hormone in a human or animal and are useful in treating or preventing a physiological condition which may be modulated by an increase in endogenous growth hormone.
Patent NZ-503493-A (NZ)
Title: Method of preventing nephrotoxicity caused by cyclosporins and tacrolimus by co-administering pentosan polysulphate (PPS)
Inventor: STRIKER GARY E
IPC: A61P39/00
Filed: 1998-10-09
Abstract: A method of preventing, reducing or reversing nephrotoxicity or renal dysfunction induced by administration of a cyclosporin or tacrolimus.  The method comprises the co-administration, per oral, either before, together with or after cyclosporin or tacrolimus administration, of a pharmaceutical composition containing an effective amount of pentosan polysulfate (PPS).  The total daily dosage of PPS or PPS salt ranges from about 2 to about 50 mg/kg of patient body weight, or about 140 to about 3,500 mg per day in adult human patients.  Also disclosed is a method of providing immunosuppressive therapy to a patient while avoiding cyclosporin or tacrolimus-induced nephrotoxicity, and combination pharmaceutical compositions to be used in such therapy.
Patent NZ-508913-A (NZ)
Title: Current detector and current measurement apparatus including such detector
Inventor: SKERRITT ROBERT CHARLES
IPC: G01R19/25
Filed: 1999-06-30
Abstract: A  current  sensor comprising a metallic  link  member having  two  end  portions  of conductive  material  and  an intermediate portion interconnecting the end portions,  said intermediate  portion being formed of a resistive  material, and  an  integrated  circuit analogue to  digital  converter mounted  on said link member, said converter having analogue input  terminals connected to respective ones  of  said  two end  portions  and  a  digital output for  connection  to  a processing apparatus.
Patent NZ-508939-A (NZ)
Title: Bovine vaccine formula comprising a plasmid containing HN and/or F genes from the type 3 parainfluenza virus
Inventor: AUDONNET JEAN-CHRISTOPHE
IPC: A61P31/14
Filed: 1997-07-06
Abstract: Disclosed is a vaccine for bovines that comprises a plasmid containing HN and/or F genes from the type 3 parainfluenza virus.  The vaccine may also comprise the cytomegalovirus early CMV-IE promoter, the SV40 later promoter, the Rous sarcoma virus LTR promoter, the desmin promoter, or the actin promoter. The vaccine may be combined with a live whole, inactivated whole, recombinant or a subunit vaccine.
Patent NZ-509936-A (NZ)
Title: Gas powered needleless injectors where the stroke of the piston can be varied by venting holes within the cylinder to permit the escape of pressurised gas
Inventor: WESTON TERENCE EDWARD
IPC: A61M5/31
Filed: 1999-08-05
Abstract: A pressurised gas powered actuator comprising a piston (3) operating in a cylinder (1). The stroke of the piston (3) may be reduced by uncovering one or more holes (not shown) in the cylinder wall to permit the escape of the pressurised gas at a predetermined position along the swept wall of the cylinder. Alternatively, the piston may be connected to a rod which has a gas vent formed therein, the position of the rod with respect to the piston being variable to adjust the stroke of the piston.
Patent NZ-510119-A (NZ)
Title: Improved collapsible shelter/tent with frame locking mechanism
Inventor: SURRENDI DENNIS C
IPC: E04H15/28
Filed: 1999-07-20
Abstract: A collapsible shelter/tent, such as for example an umbrella tent, has a collapsible frame with a plurality of legs that are erected by manually moving two clevises toward one another. The shelter/tent includes an improved locking mechanism that very securely maintains the structure in an erected position. The improved locking mechanism includes a generally vertical pin extending from one of the clevises that is received inside a socket supported on the other of said clevises. The socket has an engaging member therein that can engage a groove in the generally vertical pin after said generally vertical pin has been inserted into said socket. Preferably, the engaging member is spring biased into the groove. The shelter/tent also includes a variety of novel frame structures. An erection device for erecting a collapsible tent is also included. The erection device includes an elongated pole and a slide member that can be used to control relative movement of the clevises toward and away from one another.
Patent NZ-510411-A (NZ)
Title: Gene regulating circadian clock function and photoperiodism
Inventor: WAGNER RY
IPC: C07H21/02
Filed: 1999-08-17
Abstract: Nucleic acid molecules that encode plant proteins involved in photoperiodism and circadian rhythms are disclosed. These molecules may be introduced into plants in order to alter the photoperiodic and/or circadian clock- based gene expression of the plants. This protein is referred to as ELF3.
Patent NZ-510934-A (NZ)
Title: Pallet stacking device for stacked arrays of containers having container tops has a contoured surface configured with an array of indentations that cooperate with the container tops
Inventor: OVERHOLT TRENTON M
IPC: B65D21/02
Filed: 1999-10-22
Abstract: A device that provides an interface between stacked arrays of containers (B) having container tops. The interface includes a pallet (36) loaded with a stacked array of containers (B) and a layer of exposed container tops adjacent the pallet (B). A plastic coupling member (10) is positioned between the layer of exposed container tops and the pallet (36). The plastic coupling member (10) includes a contoured surface configured with an array (16) of indentations formed therein and properly spaced to mate with each of the layer of exposed container tops. The array (16) of indentations is sufficiently deep to prevent relative lateral displacement of the coupling member (10) with respect to the layer of exposed container tops. A method of vertically stacking crates (38, 40, 42, 44, 46) using such an interface is also provided.
Patent NZ-511394-A (NZ)
Title: N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
Inventor: KO SOO S
IPC: C07D211/28
Filed: 1999-12-17
Abstract: A compound of formula (I) wherein M is absent or selected from CH2, CHR5, CHR13, CR13R13, and CR5R13; Q is selected from CH2, CHR5, CHR13, CR13R13, and CR5R13;.J and K are selected from CH2, CHR5, CHR6, CR6R6 and CR5R6; L is CHR5; with the proviso that: when M is absent, J is selected from CH2, CHR5, CHR3, and CR5RI3; Z is selected from O and S; E is a cyclic group; R1 and R2 are independently selected from H, and optionally substituted with alkyl, alkenyl, alkynyl, and a (CH2)r cycloalkyl, and a (CH2)r carbocyclic residue; R3 is selected from a (CR3'R3")r carbocyclic residue substituted with 0-5 R15 and a (CR3'R3")r membered heterocyclic system containing 1-4 heteroatoms selected from N, O, and S, substituted with 0-3 R15; for use in the modulation of chemokine activity in order to treat or prevent inflammatory disease.
Patent NZ-512077-A (NZ)
Title: Carbamate derivatives of diaryl 1,3,4-oxadiazolone
Inventor: HEWAWASAM PIYASENA
IPC: A61P9/10
Filed: 2000-01-20
Abstract: Carbamate oxadiazolone derivatives having general formula (I) wherein: R1 is a hydrogen, C1-4 alkyl, -CR3R4CO2H, -(CH2)2-NR5R6; and R2 is hydrogen, C1-4 alkyl; or R1 and R2 taken together with the nitrogen atom to which they are attached, is a heterocyclic ring selected from piperazine, N-methyl piperazine, piperidine, thiomorpholine and morpholine.  Also disclosed are their uses in the treatment of disorders which are responsive to the opening of the large conductance calcium-activated potassium channels.
Patent NZ-515203-A (NZ)
Title: Method and apparatus for treating dental caries
Inventor: HAMILTON DAVID CORBETT
IPC: A61C5/00
Filed: 2000-04-14
Abstract: A procedure for treating dental caries is described comprising the steps of gaining access to a carious lesion, contacting the lesion with a photosensitiser, activating the photosensitiser by exposing the lesion to light of a wavelength which is absorbed by the photosensitiser using an optical fibre permitting illumination of the area of the lesion to kill bacteria in the region of the lesion, and infusing the treated dentine with a polymerisable sealing or filling composition and causing said composition to cure. Claims of this application are directed to the use of elements for manufacturing a kit of parts.
Patent NZ-515579-A (NZ)
Title: Method and apparatus for producing plant container liners particularly from sphagnum moss
Inventor: JUST PERRY
IPC: A01G9/02
Filed: 2002-03-31
Abstract: Apparatus for forming three dimensional shaped products from particulate sphagnum moss material including: a conveyor including a belt (50) formed of a flexible and resiliently deformable material and arranged to carry the particulate material and to move in steps; means for continuously delivering particulate moss material (23) onto the conveyor for conveying to a press forming stage and a spreader (40) for spreading the particulate material to a substantially even thickness layer on the belt of the conveyor; a press forming stage including a cavity die member (27) positioned beneath the belt of the conveyor and including a die shaped cavity, and a co-operating die member (26) positioned above the belt of the conveyor which delivers fresh particulate moss material between the die members, to press the section of the belt of the conveyor between the die members and the particulate material thereon into the cavity die member, to form a shaped product, the belt of the conveyor having sufficient resilience to lift the press formed product from the cavity die member after each operation of the press forming stage, and the conveyor being arranged to convey the formed products away from the press forming stage.
Patent NZ-519797-A (NZ)
Title: Treating allergic and inflammatory conditions
Inventor: SALMUN LUIS M
IPC: A61K31/473
Filed: 2001-02-01
Abstract: Described is the use of desloratadine for the preparation of a medicament for treating and/or preventing congestion associated with allergic and inflammatory conditions of the airway passages in a human in need thereof which comprises an amount of desloratadine effective for such treating and/or preventing. Further described is the use of desloratadine for the preparation of a medicament for treating and/or preventing congestion associated with allergic and inflammatory conditions in a human in need thereof which comprises an amount of desloratadine effective for such treating and/or preventing in combination with one or more additional decongestants.
Patent NZ-523010-A (NZ)
Title: Lactic acid bacteria strains and their use as probotics for pet food
Inventor: ZINK RALF
IPC: A23K1/00
Filed: 2001-05-22
Abstract: An isolated strain of lactic acid bacteria having an effective amount of probiotic activity in pets that is capable of reviving and colonizing the gastrointestinal tract of pets is described. Preferably the strain is selected from Lactobacillus, Bifidobacterium or Enterococcus, and is selected from Lactobacillus reuteri NCC2581 (CNCMI-2448), Lactobacillus reuteri NCC2592 (CNCM I-2450), Lactobacillus rhamnosus NCC2583 (CNCM1-2449), Lactobacillus reuteri NCC2603 (CNCMI-2451), Lactobacillus reuteri NCC2613 (CNCMI-2452), Lactobacillus acidophilus NCC2628 (CNCM 1-2453). The lactic acid bacteria can be used in pet food compositions for treating disorders associated with the colonization of the gastrointestinal tract of pets by pathogenic microorganisms, regulating the immune system, improving the health of the skin and/or coat system and reducing the effects of aging of pets.
Patent NZ-523660-A (NZ)
Title: A reactor comprising a packed bed of supported catalyst or supported catalyst precursor, and a use of the reactor
Inventor: NIESEN GERARDUS PETRUS LAMBERT
IPC: C10G2/00
Filed: 2001-07-11
Abstract: A process for preparing hydrocarbons from a mixture of carbon monoxide and hydrogen in the presence of a catalyst is carried out in a reactor comprising a packed bed of supported catalyst comprising a group VIII metal, which is present at least in the metallic form. The supported catalyst comprises an external surface comprising the catalytically active metal. The packed bed has a void content of more than 50%v and a specific area of more than 10 cm2/cm3, which is calculated, as the total external surface area of the particles relative to the bed volume. The group VIII metal is cobalt.
Patent NZ-531941-A (NZ)
Title: Light gauge steel ribbed-channel, self-setting lath and framing system
Inventor: STEVENS DONALD A
IPC: E04B9/04
Filed: 2002-08-30
Abstract: A two-part building framing system comprised of a half inch ribbed channel expanded metal lath (10) and light gauge steel frame (15). The lath (10) self sets into the flanges (25) of a pre-fabricated steel frame (15) without the use of fasteners and can be used over an open-cavity without the use of a solid substrate. The metal lath (10) and steel frame (15) can be used in various building application and structures.
Patent NZ-536008-A (NZ)
Title: Method of maintaining the appearance or colour of a cut of meat
Inventor: PALMER ROGER KEITH
IPC: A23L5/41
Filed: 2004-10-15
Abstract: A method of maintaining a desirable fresh and/or healthy appearance of a cut of meat during retail display including the steps of: controlling the temperature within a range sufficient to suppress oxygen consuming reactions and to effect the rate of myoglobin conversion to metmyoglobin, following cutting of said meat from a meat primal; and maintaining said meat at said temperature in an oxygenated environment for a predetermined extended period of time before transfer to a retail display temperature.
Patent NZ-536264-A (NZ)
Title: Water heater apparatus and associated manufacturing and insulation methods
Inventor: HICKS KENNETH J
IPC: F24H1/18
Filed: 2004-11-01
Abstract: An insulated tank apparatus comprising: a tank (14), a jacket (28) extending outwardly around the tank and defining a cavity (26) between the jacket and the tank; a flexible bag (42) disposed in a first portion of the cavity in sealing engagement with facing portions of the tank and the jacket, the bag having wall openings (60) therein that face a second portion of the cavity; a first quantity of hardened insulation material (66) disposed in the bag, a small portion of the hardened insulation material projecting outwardly through the wall openings to define spaced apart locking protrusions (68) on the external surface of the bag; and a second quantity of hardened insulation material (40) placed in a second portion of the cavity after the hardening of the first insulation quantity and mechanically interlocked with the locking protrusions.
Patent NZ-539606-A (NZ)
Title: Antigenic peptides
Inventor: MAKSYUTOV AMIR ZAKIEVICH
IPC: C07K14/16
Filed: 2003-09-25
Abstract: Disclosed is a peptide library comprising a family of peptides having the formula: N-N-N-T-R-K-X1-X2-X3-X4-X5-G-X6-X7-X8-Y-X9-T-G-X10-I-IG-X11-I-R-Q.
Patent NZ-545805-A (NZ)
Title: Compound capable of binding S1P receptor and pharmaceutical use thereof
Inventor: NAKADE SHINJI
IPC: C07D205/04
Filed: 2004-08-27
Abstract: Disclosed is a compound represented by formula (I-S-7a) wherein: ring A represents a C5-12 monocyclic or bicyclic carbocyclic group or a 5- to 12-membered monocyclic or bicyclic heterocyclic group which contain 1 to 3 hetero atoms selected from an oxygen atom, a nitrogen atom and a sulfur atom; X represents a divalent group having 1 to 8 atoms in its main chain which contains 1 to 4 functional groups selected from C1- alkylene, C1-8 alkylene substituted with 1 to 3 halogen atoms or methyl, C2-8 alkenylene, C2-8 alkylene substituted with 1 to 3 halogen atoms or methyl, a nitrogen atom, a nitrogen atom substituted with methyl, -CO-, -O-, -S-, C3-6 cycloalkylene, C3-6 cycloalkylene substituted with 1 to 3 halogen atoms or methyl, phenylene, and phenylene substituted with 1 to 3 halogen atoms and wherein the rest of the substituents are disclosed within the specification. Also disclosed is the use of the above compound in the manufacture of a medicament for preventing and/or treating a disease related to EDG-1 and/or EDG-6.
Patent NZ-546179-A (NZ)
Title: Back support harness arrangment
Inventor: MURRAY DARYN LLOYD
Filed: 2006-03-27
Abstract: A back support harness arrangement comprising a back support harness configured and arranged to be worn by a user to provide support to their back and shoulders, a support frame, and a tether means connecting the harness to the frame, the tether means including a tether extension/retraction means mounted on the support frame to enable the tether length to be extended or retracted, tether locking means operable to lock the tether extension/retraction means and prevent the tether length from being extended, and tether lock release means operable to release the tether lock means.
Patent NZ-550335-A (NZ)
Title: Traditional chinese medicine preparation for cardio-cerebral blood vessel diseases and its preparing method
Inventor: CHENG YIYU
IPC: A61K31/045
Filed: 2005-03-17
Abstract: Disclosed is a traditional Chinese medicinal preparation for cardio-cerebral blood vessel diseases, wherein the medicinal preparation is prepared though extracting danshen and notoginseng by lye , precipitating with alcohol, concentrating, and adding other medicine and excipients. Then using the HPLC-MS and HPLC fingerprint Atlas to characterise its physico-chemical properties completely. Using the fingerprint Atlas analysis method of the present invention, the structure and comparative content of biology active component can be known. Characterisation of the physico-chemical properties of danshen and notoginseng of traditional Chinese medicinal preparation with this way is better than other methods of the prior art.
Patent NZ-555746-A (NZ)
Title: Herbicidal composition comprising prosulfocarb and either metolachlor or S-metolachlor
Inventor: KOTZIAN GEORG RUDIGER
IPC: A01N37/22
Filed: 2005-12-15
Abstract: Disclosed is a herbicidal composition comprising prosulfocarb and at least one of metolachlor andd S-metolachlor. Also discloses is the use of the composition to control undesired vegetation in crops of useful plants.
Patent NZ-560574-A (NZ)
Title: Agent stabilisation process and product comprising biopolymer and desiccant
Inventor: SWAMINATHAN JAYANTHI
IPC: A23L19/00
Filed: 2007-11-07
Abstract: Provided is a composition including: (a) a substrate selected from the group comprising edible solids or semi-solids, biodegradable solids or semi-solids, clay, biopolymers or a combination thereof; (b) a first coating that at least partially coats the surface of the substrate including: at least one gum based biopolymer; and an aqueous concentrate of biological material comprising a microorganism; and, (c) a second coating that at least partially coats the surface of the first coating including at least one desiccation agent.
Patent NZ-575979-A (NZ)
Title: Thiophene derivatives as s1p1/edg1 receptor agonists
Inventor: BOLLI MARTIN
IPC: A61K31/381
Filed: 2007-07-10
Abstract: Disclosed are tricyclic aryl thiophene derivatives and their salts as represented by the general formula (I) wherein: A represents an oxazole, oxadiazole, thiazole or thiadiazole moiety as defined herein; or A represents -CO-CH2CH2- or -CO-CH=CH-; R1 represents alkyl; R2 represents hydrogen, methyl or ethyl; R3 represents hydrogen; R4 represents methyl, ethyl, or methoxy; R6 represents methyl, ethyl or halogen; and R5 represents a substituent as defined herein. Of particular importance are the compounds 2-hydroxy-N-((2S)-2-hydroxy-3-{ 4-[5-(5-isobutyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-2,6-dimethyl-phenoxy} -propyl)-acetamide; N-((2S)-3-{ 2-ethyl-6-methyl-4-[5-(5-propyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-phenoxy} -2-hydroxy-propyl)-2-hydroxy-acetamide; (2R)-3-{ 2-ethyl-4-[5-(5-isobutyl-4-methyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl-6-methyl-phenoxy} -propane-1,2-diol; (2S)-3-{ 2-ethyl-4-[5-(5-isobutyl-4-methyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-6-methyl-phenoxy} -propane-1,2-diol; N-((2R)-3-{ 2-ethyl-4-[5-(5-isobutyl-4-methyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-6-methyl-phenoxy} -2-hydroxy-propyl)-2-hydroxy-acetamide and N-((2S)-3-{ 2-ethyl-4-[5-(5-isobutyl-4-methyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-6-methyl-phenoxy} -2-hydroxy-propyl)-2-hydroxy-acetamide. Further disclosed is a pharmaceutical composition which comprises a compound as defined above, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, for the prevention or treatment of diseases or disorders selected from the group consisting of rejection of transplanted organs such as kidney, liver, heart, lung, pancreas, cornea, and skin; graft-versus-host diseases brought about by stem cell transplantation; autoimmune syndromes including rheumatoid arthritis, multiple sclerosis, inflammatory bowel diseases such as Crohn's disease and ulcerative colitis, psoriasis, psoriatic arthritis, thyroiditis such as Hashimoto's thyroiditis, uveoretinitis; atopic diseases such as rhinitis, conjunctivitis, dermatitis; asthma; type I diabetes; post-infectious autoimmune diseases including rheumatic fever and post-infectious glomerulonephritis; solid cancers and tumour metastasis.
Patent NZ-576314-A (NZ)
Title: Antimicrobial composition comprising 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one and thifluzamide
Inventor: ASHMORE JOHN WILLIAM
IPC: A01N33/04
Filed: 2006-06-08
Abstract: Disclosed is a synergistic antimicrobial composition comprising 4,5-dichloro-2-n-octyl, 4-isothiazolin-3-one and thifluzamide, and also its use in inhibiting the growth of microorganisms. (62) Divided Out of 563783
Patent NZ-585523-A (NZ)
Title: Safety stylet
Inventor: TYUKODY DOUG
IPC: A61B17/06
Filed: 2008-11-21
Abstract: 585523 A safety stylet 1 for insertion within a cannula of a needle 10, comprising a solid elongated shaft having a proximal end adapted for engagement with a needle hub, and a distal end having a dull, planar contact surface 19. The contact surface 19 has a surface modified profile. The surface modified profile comprises a roughened surface.