baber/WOPTO huggingface dataset:
Patent DE-69422818-T2 (DE)
Inventor: LUNDQUIST STEFAN
IPC: A61K47/44
Filed: 1994-10-05
Granted: 2000-07-27
Abstract: PCT No. PCT/SE94/00926 Sec. 371 Date Jan. 30, 1995 Sec. 102(e) Date Jan. 30, 1995 PCT Filed Oct. 5, 1994 PCT Pub. No. WO95/09609 PCT Pub. Date Apr. 13, 1995The present invention is related to a pharmaceutical formulation which is an oil-in-water emulsion for parenteral and oral use which comprises (i) an emulsion-stabilizing surface active drug in high concentration; (ii) optionally a pharmacologically inert oil; (iii) optionally a surfactant; (iv) water or a buffer; and (v) an agent giving isotonicity to the final formulation; the use of and a process for preparation of the formulation.
Patent DE-69426480-T2 (DE)
Inventor: MCADAM KEVIN GERARD
IPC: A24D3/04
Filed: 1994-09-26
Granted: 2001-04-19
Abstract: This invention relates to a method which provides in a cigarette filter element a capsule containing a deodoriser. The capsule is resistant to the handling endured before and during smoking, and is ruptured to release or expose the deodoriser after smoking has occurred and upon extinguishing of the smoked cigarette. The deodoriser may comprise neutralising or masking agents, or mixtures of both. <IMAGE>
Patent DE-69431185-T2 (DE)
Inventor: RUSSELL-JONES GREGORY JOHN
IPC: A61K47/48
Filed: 1994-05-24
Granted: 2003-05-08
Abstract: The invention relates to the oral delivery of peptide and protein pharmaceuticals using the vitamin B12 (VB12) uptake system, with the delivery being amplified using polymers. More particularly, the invention concerns a complex having the general formula: (V-Q)n-P-(Q'-A)m where, V is a carrier which will bind to natural intrinsic factor (IF) selected from vitamin B12 or an analogue thereof, n is the molar substitution ratio of V in the complex, and is a number from 1.0 to about 10, P is a pharmaceutically acceptable polymer, A is a pharmaceutically active substance, m is the molar substitution ratio of A in the complex, and is a number greater than 1.0 to about 1000, Q and Q' are independently a covalent bond, or a spacer compound linking V, P and A by covalent bonds.
Patent DE-69432596-T2 (DE)
Inventor: YIM KALVIN W K
IPC: A61K38/00
Filed: 1994-09-02
Granted: 2004-03-18
Abstract: A composition is disclosed comprising a pharmaceutically acceptable admixture of an osteogenic protein; a porous particulate polymer matrix; an osteogenic protein-sequestering amount of blood clot; and a calcium sulfate hemihydrate-containing substance. Also disclosed are formulations of bone morphogenetic proteins with improved solubility and/or stability characteristics.
Patent DE-69504346-T2 (DE)
Inventor: HUET DANIEL
IPC: B01J2/02
Filed: 1995-06-21
Granted: 1999-04-01
Abstract: PCT No. PCT/FR95/00824 Sec. 371 Date Apr. 14, 1997 Sec. 102(e) Date Apr. 14, 1997 PCT Filed Jun. 21, 1995 PCT Pub. No. WO95/35158 PCT Pub. Date Dec. 28, 1995The invention relates to a process for atomizing a dispersible liquid material or a mixture of dispersible liquid materials, characterized in that the dispersible liquid material (3) or the mixture is dispersed in the form of particles (7) by spraying at least one stream of solid particles (6) which are reactive as a result of their partial or total coating onto the material and the particles (7) are collected in a receiving medium.
Patent DE-69506699-T2 (DE)
Inventor: BLUMBERG BARRY B
IPC: G07C15/00
Filed: 1995-05-02
Granted: 2001-03-08
Abstract: A promotional game wherein prizes are automatically and randomly awarded upon presentation of multiple tokens bearing machine readable codes. The random generation of prize awards will take place after the multiple inputs of machine readable codes include a set of inputs which match a preselected set of actuating codes.
Patent DE-69520768-T2 (DE)
Inventor: ARCE MENDIZABAL FLAVIA
IPC: A61K31/137
Filed: 1995-07-17
Granted: 2001-08-23
Abstract: Pharmaceutical formulations of fluoxetine or an acid addition salt thereof, suitable for manufacturing dispersible tablets by direct compression and comprising, in addition to the active ingredient, the appropriate excipients and coadjuvants, selected from among disintegrants, diluents, lubricants, anti-adherents, sweeteners, flavorings and, optionally, colorants.Said formulations are suitable for manufacturing dispersible tablets which disintegrate in less than three minutes in water at 19•C - 21•C, and are appropriate for treatment of depression.
Patent DE-69520801-T2 (DE)
Inventor: ZANONI ADELFIO
IPC: C03C27/12
Filed: 1995-01-16
Granted: 2002-01-17
Abstract: In order to avoid the wearing down (attrition) effects on the layer of interferential material (4), the method provides for said layer of interferential material (4) to be sandwiched between a first element of transparent material (1) and a second element of transparent material (5). <IMAGE>
Patent DE-69524160-T2 (DE)
Inventor: EHROLA JUHA
IPC: F16C13/00
Filed: 1995-07-25
Granted: 2002-06-20
Abstract: The invention concerns a variable-crown roll loaded by means of shoes, comprising a stationary roll axle (12), around which a tubular roll mantle (11) is fitted revolving, which roll mantle is mounted by its ends on the roll axle (12) by means of end bearings (13a,13b). Hydraulic loading shoes (151...15n) are fitted between the roll mantle (11) and the roll axle (12), which shoes act upon the inner face of the roll mantle (11) in the nip plane and are supported on the roll axle (12) and which shoes are loaded by means of a hydraulic pressure medium, and the nip pressure can be profiled in the axial direction of the roll (10) by regulating the pressure of the pressure medium passed into said loading shoes. The roll mantle (11) is made of a fibre-reinforced composite material so that the stability of shape of the roll mantle (11) in the direction of the circumference is good and the rigidity in the axial direction is low. <MATH>
Patent DE-69525029-T2 (DE)
Inventor: VAN DEN ENDEN JOSEPH
IPC: H04N9/797
Filed: 1995-09-05
Granted: 2002-09-05
Abstract: Arrangement for reproducing a data reduced digital video signal, in a feature mode with the record carrier speed being larger than nominal. The reproducing arrangement comprises reading means for reading a signal from said track, decoding means (175) for decoding the signal read from said track so as to obtain the data reduced digital video signal and an output terminal for supplying the data reduced digital video signal. The data reduced digital video signal comprising first signal blocks having data reduced video information obtained from video information of a picture that has been subjected to an intra-picture encoding step prior to recording, and comprising second signal blocks having data reduced video information obtained from video information of a picture that has been subjected to an inter-picture encoding step prior to recording. The reproducing arrangement is a reproducing arrangement of the linear reproducing type, and the reading means comprise a reading head (142) for reading information from the track, memory means (140) for storing information read from the track with a first rate and reading out said information with a second rate, said second rate being lower than said first rate, detection means (152) for detecting the start of a first signal block present in the signal read from the track, address generating means (148,149) for generating read-in addresses at said first rate, and for generating read-out addresses at said second rate, comparator means (156) for comparing a filling degree of the memory means with a threshold value (Ta), and that the reading means are adapted to carry out the following steps,   (a) the address generating means are adapted to generate subsequent read-in addresses at said first rate and read-out addresses at said second rate, starting with a start address, for storing the information in and reading the information from subsequent storage locations in said memory means, (b) that upon the detection of the start of a first signal block present in the information read out from the memory by the detection means, an enable signal is generated so as to enable the decoding unit to start decoding the information corresponding to said first signal block, (c) that upon detection of the current filling degree being larger than or equal to said threshold value, the storage of information in said memory means is terminated, and that the reading means are adapted to return to (a) in response to termination of the decoding of said first signal block.   <IMAGE>
Patent DE-69525162-T2 (DE)
Inventor: DELCEA BOGDAN
IPC: H05H1/42
Filed: 1995-06-19
Granted: 2002-08-22
Abstract: A plasma torch incorporating an arc forming a chamber in which a cathode cooperates with an anode to form a plasma arc. A splitter is connected to the arc forming chamber and comprises a plurality of passages arranged about a core region, the passages leading from the arc forming chamber into a nozzle passage extending along the axis of the arc forming chamber. A feed passage passes through the core region, opening co-axially with the longitudinal axis of the torch, in or about the region of coalescence of the plasma stream exiting the splitter passages. Feedstock material, such as powder, is fed through the feed passage into the coalesced plasma stream in an axial direction and in its direction of travel.
Patent DE-69531241-T2 (DE)
Inventor: MURPHY TIMOTHY F
IPC: A61K39/07
Filed: 1995-04-20
Granted: 2004-06-03
Abstract: Compositions comprising outer membrane protein "E", and peptides and oligopeptides thereof, of Moraxella catarrhalis are described. Additionally, nucleotide sequences encoding the protein, peptide, or oligopeptide are disclosed, as well as recombinant vectors containing these sequences. Protein, peptide, or oligopeptide can be produced from host cell systems containing these recombinant vectors. Peptides and oligopeptides can also be chemically synthesized. Disclosed are the uses of the protein, peptides and oligopeptides as antigens for vaccine formulations, and as antigens in diagnostic immunoassays. The nucleotide sequences are useful for constructing vectors for use as vaccines for insertions into attenuated bacteria in constructing a recombinant bacterial vaccine and for inserting into a viral vector in constructing a recombinant viral vaccine. Also described is the use of nucleotide sequences related to the gene encoding E as primers and/or probes in molecular diagnostic assays for the detection of M. catarrhalis.
Patent DE-69534657-T2 (DE)
Inventor: RAMSDEN JOHN NIGEL
IPC: F02B39/14
Filed: 1995-09-25
Granted: 2006-06-14
Abstract: A turbocharger module (100) for a turbocharged internal combustion engine comprises turbocharger cartridges (850), each having a turbine rotor (814) and a compressor impeller (812) mounted on a common shaft (816) running in bearings (809). Each cartridge is held in a bore (851) in a wall (90) of a supporting enclosure (9), with its turbine rotor projecting into the enclosure and its compressor impeller outside the enclosure. A turbine housing (800) is fitted tightly to an internal wall surface region (807) surrounding each bore to provide a low thermal resistance path to heat flow by conduction from the turbine housing (800) into the wall (90). When installed in the bores, the turbine rotors of the cartridges fit into the turbine housings, the cartridges being held concentric with the turbine housing by a spigot (870) having a close fit in a circular register (871) in the turbine housing. The spigot and the register contact each other over an annular region which is substantially smaller in area than the area of contact between the turbine housing (800) and the internal wall surface region (807), the spigot and the register providing the only significant region of direct mechanical contact between the turbine casing (800) and the cartridge (850). Hence, during operation of the cartridges, heat from the turbine casing is shunted away from the cartridges into the wall (90) of the enclosure (9). Preferably, the wall is actively cooled. <IMAGE>
Patent DE-69603264-T2 (DE)
Inventor: GODIN NORMAN
IPC: A61F2/24
Filed: 1996-02-28
Granted: 2000-04-13
Abstract: PCT No. PCT/IB96/00149 Sec. 371 Date Sep. 23, 1997 Sec. 102(e) Date Sep. 23, 1997 PCT Filed Feb. 28, 1996 PCT Pub. No. WO96/29954 PCT Pub. Date Oct. 3, 1996A prosthesis in the form of a flexible tube having a substantially uniform cross section is disclosed. The prosthesis comprises a flange (2) for endoscopically placing stitches or clips in a hiatal hernia (3), and a flexible tubular portion (1) enabling the tube to be squeezed by exerting a pressure (F) on the outer surface thereof in order to prevent reflux of the stomach contents into the esophagus. Food can pass freely through the prosthesis in the direction from the esophagus (4) to the stomach (5). The prosthesis is made of a biocompatible polymer optionally containing barium sulphate to make it detectable using X-rays.
Patent DE-69611732-T2 (DE)
Inventor: FREDRIKSSON BOERJE
IPC: D21D5/02
Filed: 1996-09-26
Granted: 2001-05-23
Abstract: PCT No. PCT/SE96/01204 Sec. 371 Date Apr. 7, 1998 Sec. 102(e) Date Apr. 7, 1998 PCT Filed Sep. 26, 1996 PCT Pub. No. WO97/13919 PCT Pub. Date Apr. 17, 1997Apparatus for screening pulp suspensions containing heavy impurities is disclosed including a casing with an inlet for the pulp suspension at the lower end of the casing, a stationary screen mounted within the casing, a rotor mounted for rotation within the stationary screen thus forming a screening zone between the rotor and the stationary screen, with the inlet disposed within the rotor, the rotor including at least one opening adjacent to its upper end for transferring the pulp into the screening zone and a chamber for the heavy impurities disposed adjacent to either the upper or lower end of the casing, the rotor including strips or grooves for moving heavy impurities from the inner surface of the rotor to the chamber.
Patent DE-69613435-T2 (DE)
Inventor: MARTIN WALLACE ANTHONY
IPC: B29C33/00
Filed: 1996-04-30
Granted: 2001-10-18
Abstract: An apparatus for forming contact lenses, wherein front curve mold halves are filled with a hardenable transparent material, such as a polymerizable hydrogel, and back curve mold halves are coupled to the front curve, therein forming a lens. More Particularly, the apparatus includes a conveyor means for transporting pallets of mold halves to the apparatus, an array of piston structures for raising and aligning the back curves with respect to the filled front curve halves, reciprocating means for reciprocating the piston array to couple pairs of front and back curves, and a vacuum chamber and vacuum drawing means for maintaining a vacuum around the curves during coupling. In addition, there is provided individual spring biasing to each reciprocating element whereby sensitivity to thickness variations and pallet misfeeds may be minimized. Further, there is provided a vacuum sleeve, through which the pistons reciprocate within the vacuum chamber, which sleeve preserves the vacuum within the chamber.
Patent DE-69625527-T2 (DE)
Inventor: STARAL S
IPC: G02F1/1339
Filed: 1996-10-23
Granted: 2003-11-06
Abstract: Process and materials are described for selectively placing uniform spacers on a receptor. Spacer elements are placed on a receptor by selectively irradiating a thermal transfer donor sheet comprising a transferable spacer layer. The transferable spacer layer may include particles or fibers to form a composite. The particles may have a spacing dimension either greater than or less than the thickness of the transferable layer. When the spacing dimension of the particle is greater than the thickness of the transferable layer, then the spacing dimension of the particles control the spacing distance. The process and materials are useful in the manufacture of flat panel displays, particularly, liquid crystal display devices.
Patent DE-69702398-T2 (DE)
Inventor: GOVINDAN V
IPC: C07K1/107
Filed: 1997-08-27
Granted: 2001-02-15
Abstract: Methods are described for conjugating radioiodinated peptides or carbohydrate structures to proteins with improved yields and qualities of conjugates. In one method, specially designed radioiodinated bifunctional peptides containing nonmetabolizable amide bonds are coupled to antibodies. In a second method, radioiodinated nonmetabolizable bifunctional peptides, which also contain aminopolycarboxylates, are coupled to antibodies. In a third method, radioiodinated bifunctional aminopolycarboxylates are coupled to antibodies. In a fourth method, a hydrazide-appended antibody is coupled to a radioiodinated carbohydrate, or a thiolated antibody is coupled to a hydrazide-appended and radioiodinated carbohydrate. In a fifth method, a monoderivatized cyanuric chloride is used to conjugate thiolated antibody. Radioiodinated residualizing antibody conjugates made by these methods are particularly stable in vivo and are suitable for radioimmunodetection and radioimmunotherapy.
Patent DE-69703848-T2 (DE)
Inventor: WITT JOYCE
IPC: B65D75/54
Filed: 1997-10-30
Granted: 2001-07-19
Abstract: A three-dimensional insert for use in a handling system comprising a sheet of cardstock or the like defined by ends and first and second sides, a laminate applied to the top surface of the cardstock, and an overwrap material bonded to the laminate proximate to the first and second sides. This structure enables a three-dimensional object to be placed within the overwrap material without risk of movement to the peripheral sides.
Patent DE-69710183-T2 (DE)
Inventor: DEELEY THOMAS
IPC: B21D13/04
Filed: 1997-03-20
Granted: 2002-07-18
Abstract: Lightweight flexure-resistant thin metal sheet is produced by passing flexible thin metal sheet between rolls having defined teeth, the teeth having radiused corners so that rows of projections are formed on both faces of the sheet without damage to the surface material or the rolls.
Patent DE-69711070-T2 (DE)
Inventor: NICHOLSON E
IPC: G01S3/783
Filed: 1997-11-14
Granted: 2002-11-21
Abstract: The invention provides a system and a method for determining the direction to a radiating source, for use by a vehicle guidance system, in which optical fibers are used to both collect and transmit optical signals in which the vehicle is preferably intended to home in on its target. The optical fibers disclosed herein require no separate collection optics, but instead directly collect incident radiation arriving at one end of the optical fiber for transmission to a photodiode detector coupled to the distal end. Preferably the radiation is laser radiation radiating from a target in relation to which the vehicle is guided, and preferably the vehicle is a guided missile. Elimination of collection optics reduces the complexity and cost of the apparatus and provides an unexpected increase in and selectability of the accuracy of directional determination by the system. The system includes an array of apertures disposed in selected, non-uniform locations on the vehicle. Each aperture contains a set of fibers, including start and stop fibers. The fibers receive incoming radiation, transmit the radiation as optical signals to start and stop detectors. The detectors measure a signal strength and a property related to the length of the start and stop fibers through which the optical signals have been transmitted, and provide output indicative of the signal strength and the property to a microprocessor. The microprocessor is programmed to calculate the direction to the radiation source relative to the vehicle, and to provide this information to a vehicle guidance and control system.
Patent DE-69719691-T2 (DE)
Inventor: BOOTHMAN ANDREW JAMES CHRISTOP
IPC: B62D25/10
Filed: 1997-11-26
Granted: 2003-11-06
Abstract: A body panel assembly for eg a tractor engine hood comprises a top panel (8), side panels (12) and a front grille panel (18). Forward ends of the top and side panels are secured to a frame (3) mounted on or integral with the front of the tractor chassis (1). The grille panel (18) is mounted at least partially by releasable means on an alignment member or members (17, 26) whose exact position may be adjusted during the assembly process to ensure accurate alignment of the front grille panel (18) to the side panel (12). <IMAGE>
Patent DE-69721316-T2 (DE)
Inventor: BATTIATO J
IPC: A61D7/00
Filed: 1997-11-18
Granted: 2004-02-19
Abstract: A medical fluid injector includes: an air detection system for detecting air in the neck of the syringe; a hand-operated control lever for controlling movement of the injector ram; magnetic conductors for delivering magnetic fields from a power head face plate to an internal circuit board to permit detection of different face plates; a tilt sensor detecting the tilt angle of the power head to control the speed of motion brought about by the hand-operated control lever and to control an invertible display; and a monitor microcontroller for monitoring the behavior of the central processing unit to detect and react to error conditions.
Patent DE-69721896-T2 (DE)
Inventor: BEDNAR THOMAS R
IPC: B23D49/10
Filed: 1997-03-12
Granted: 2004-05-19
Abstract: A reciprocating saw having a main body, a reciprocating spindle extending from the main body, and a saw blade connected to the spindle and including a cutting edge for cutting the workpiece. A shoe is pivotally mounted relative to the main body at a pivot axis, and a shoe support extends from the main body to pivotally support the shoe at the pivot axis. The pivot axis is substantially adjacent to the cutting edge such that the pivot axis moves through the workpiece at substantially the same time as the cutting edge. The shoe support includes a post connected to and extending from the body, and a yoke connected to the post, the yoke including two leg portions pivotally connected to the shoe. The shoe is pivotally mounted at a pivot part that is recessed inwardly from a side guide surface. The shoe includes an indicator in alignment with the saw blade to facilitate alignment of the saw blade with a mark on the workpiece.
Patent DE-69734450-T2 (DE)
Inventor: MCLAUGHLIN N
IPC: A61P31/12
Filed: 1997-03-26
Granted: 2006-08-10
Abstract: A method of treating chronic HCV infections is disclosed. The method involves the optional treatment of a patient with interferon alpha and the treatment of a patient's blood with a psoralen compound followed by ultra violet light-activation of the psoralen compound. The blood treated as such is returned to the patient in a process known as extracorporeal photopheresis.
Patent DE-69736625-T2 (DE)
Inventor: LEE RON CLARK
IPC: B01F3/08
Filed: 1997-11-07
Granted: 2007-08-30
Abstract: A stream 12 of liquid nitrogen is withdrawn at a controlled pressure from a storage tank 16 and a stream 10 of liquid oxygen is withdrawn from a storage tank 14. The two streams are passed cocurrently through a heat exchanger 20. The liquid oxygen is sub-cooled and the liquid nitrogen partially vaporised by indirect heat exchange therebetween within the heat exchanger 20. The resulting partially vaporised liquid nitrogen is separated into a liquid phase and a vapour phase within a phase separator 32. A stream of the liquid phase is withdrawn from the phase separator 32 and is mixed with the sub-cooled liquid oxygen, preferably in a mixing tee 38. <IMAGE>
Patent DE-69737107-T2 (DE)
Inventor: ZHANG SHUYUAN
IPC: A61K35/761
Filed: 1997-11-20
Granted: 2007-07-12
Abstract: The present invention addresses the need to improve the yields of viral vectors when grown in cell culture systems. In particular, it has been demonstrated that for adenovirus, the use of low-medium perfusion rates in an attached cell culture system provides for improved yields. In other embodiments, the inventors have shown that there is improved Ad-p53 production with cells grown in serum-free conditions, and in particular in serum-free suspension culture. Also important to the increase of yields is the use of detergent lysis. Combination of these aspects of the invention permits purification of virus by a single chromatography step that results in purified virus of the same quality as preparations from double CsCl banding using an ultracentrifuge.