baber/WOPTO huggingface dataset:
Patent CA-2794483-C (CA)
Title: Vista, une proteine mediatrice regulatrice des lymphocytes t, agents de liaison a vista et utilisation associee
Inventor: NOELLE RANDOLPH J
IPC: A61P37/00
Filed: 2011-03-25
Granted: 2020-07-07
Abstract: La présente invention concerne une nouvelle protéine régulatrice des lymphocytes T. Cette protéine, appelée PD-L3 ou VISTA, ressemble à des membres de la famille des PD-L1, et a été identifiée comme un ligand inhibiteur, nouveau et structurellement distinct, de la superfamille des Ig, dont le domaine extracellulaire présente une homologie avec le ligand PD-L1 de la famille B7. Cette molécule est appelée PD-L3 ou VISTA, ou suppresseur de type immunoglobuline à domaine V de l'activation des lymphocytes T (V-domain Immunoglobulin Suppressor of T cell Activation, VISTA). L'expression de VISTA se fait avant tout dans le compartiment hématopoïétique et est fortement régulée par les APC (cellules présentatrices d'antigènes) et les lymphocytes T. L'intervention thérapeutique sur la voie inhibitrice de VISTA représente une nouvelle approche de la modulation de l'immunité induite par les lymphocytes T, dans le traitement d'une variété étendue de cancers, par exemple les cancers de l'ovaire et de la vessie et les mélanomes. Les protéines VISTA, en particulier les protéines multimères de VISTA, peuvent également être utilisées pour supprimer l'immunité due aux lymphocytes T lors de maladies auto-immunes, d'allergies, d'infections et d'états pathologiques inflammatoires, par exemple la sclérose en plaques et des états pathologiques arthritiques comme la polyarthrite rhumatoïde (RA).
Patent CA-2801914-C (CA)
Inventor: SPLENDORE MAURIZIO A
IPC: H01J49/26
Filed: 2013-01-08
Granted: 2016-03-01
Abstract: An ion guide that transports ions from an ion source at generally a high- pressure level to a mass analyzer at generally a low-pressure level has a plurality of identical electrodes fabricated with protruding elements that forming an ion tunnel or an ion funnel, when the electrodes are assembled around a common longitudinal axis. The protruding elements allow the generation of the radio frequency field necessary to radially confine ions. Each electrode may be machined from a solid block of conductive material, such as metal. The disclosed arrangement greatly simplifies the manufacturing process, reducing cost, and improving robustness and reliability of the ion guide itself.
Patent CA-2811013-C (CA)
Inventor: KUYU SELMA
IPC: C08G77/20
Filed: 2011-10-05
Granted: 2016-01-19
Abstract: L'invention concerne une classe d'agents de réticulation de polysiloxane linéaire à chaîne étendue qui comprend deux groupements terminaux éthyléniquement insaturés, au moins deux segments de polysiloxane, et des chaînes de polymère hydrophile pendantes chacune attachée par covalence à un radical organique divalent séparant chaque paire de segments de polysiloxane adjacents. La présente invention concerne aussi un polymère comprenant des unités de réticulation dérivées de l'agent de réticulation de polysiloxane à chaîne étendue de l'invention et des lentilles ophtalmiques comprenant un tel polymère.
Patent CA-2811737-C (CA)
Title: Cadre porteur d'engrenage
Inventor: NOREM DEAN A
IPC: F16H57/08
Filed: 2013-04-02
Granted: 2015-11-24
Abstract: Un assemblage d'engrenage planétaire comprend un planétaire, des engrenages planétaires activant le planétaire, une couronne planétaire reliée aux engrenages planétaires, la couronne planétaire activant les engrenages planétaires, et un cadre de soutien incluant au moins une paire de bandes de confinement des roulements, une pluralité de segments reliés, une pluralité de portions d'ailettes et une portion de moyeu, où chaque paire de bandes de confinement est reliée à une paire adjacente de bandes de confinement de roulements avec un segment de liaison de la pluralité de segments de liaison et une portion d'ailette de la pluralité de portions d'ailettes connecte chaque segment de liaison à la portion de moyeu.
Patent CA-2813732-C (CA)
Inventor: GODFREY CRAIG W
IPC: E21B17/01
Filed: 2010-11-20
Granted: 2016-10-18
Abstract: A rotating control device can include a housing assembly, a body and a clamp device which releasably secures the housing assembly to the body. The clamp device can include a piston which radially displaces a clamp section. A well system can include a rotating control device which includes at least one seal which seals off an annulus between a body of the rotating control device and a tubular string which extends longitudinally through the rotating control device. The rotating control device can also include a piston which displaces longitudinally and selectively clamps and unclamps a housing assembly to the body.
Patent CA-2815618-C (CA)
Inventor: HALAIS CHRISTOPHE
IPC: C10L1/02
Filed: 2011-12-16
Granted: 2018-10-23
Abstract: Method for converting hydrocarbon feedstock comprising a shale oil, comprising a step of hydroconverting in an ebullating bed, a step of fractionating by atmospheric distillation into a light fraction, a naphtha fraction, a gas-oil fraction and a fraction heavier than the gas-oil fraction, a step of liquid/liquid extraction of the fraction heavier than the gas-oil fraction, and a dedicated hydrotreating for each of the naphtha and gas-oil fractions. The method aims to maximize the yield of fuel bases.
Patent CA-2817261-C (CA)
Inventor: MUELLER JOERG
IPC: A47K10/42
Filed: 2012-03-14
Granted: 2016-01-26
Abstract: A method of reducing a wetness gradient development for a package of wet wipes is provided. The method includes, after wet wipes are enclosed within a package to form the package of wet wipes, locating the package of wet wipes in a first orientation such that a first side of the package of wet wipes faces downward and an opposite second side of the package of wet wipes faces upward to form a first wetness gradient after a preselected amount of time. Prior to opening the package of wet wipes to access the wet wipes enclosed within the package of wet wipes, inverting the package of wet wipes according to a predetermined turning schedule to place the package of wet wipes in a second orientation such that the first side of the package of wet wipes faces upward and the second side of the package of wet wipes faces downward to form a second wetness gradient that is different from the first wetness gradient.
Patent CA-2818055-C (CA)
Inventor: ROCH NICHOLAS C
IPC: B01D1/26
Filed: 2013-04-18
Granted: 2013-11-26
Abstract: The present disclosure describes a modular humidification-dehumidification (HDH) apparatus and system for concentrating a solution including a plurality of internal modules coupled to each other.                                                 The plurality of internal modules includes a humidification module and a dehumidification module in gas flow communication with the humidification module. The humidification module includes humidification media facilitating evaporation of liquid from the solution to gas as the solution passes through the humidification media thereby producing a concentrated solution and a humidified gas. The dehumidification module includes a condensing heat exchanger for condensing vapour from the humidified gas.
Patent CA-2818191-C (CA)
Title: Procede de preparation de commandes et d'expedition
Inventor: STOTZNER MATTHIAS
IPC: B65G1/137
Filed: 2011-11-17
Granted: 2019-06-18
Abstract: L'invention concerne un procédé combiné de préparation de commandes et d'expédition, selon le principe dit « marchandise à l'homme » (prélèvement automatique), au cours duquel des conteneurs d'expédition (VB) et des unités à emballer (VP) sont acheminés à un poste d'expédition (6), et un préposé à l'emballage, qui se trouve au niveau du poste d'expédition, place manuellement les unités à emballer ayant été transportées directement au poste d'expédition, sur une unité d'expédition correspondante (VE). Le préposé à l'emballage collecte des articles individuels (A) transportés au poste d'expédition dans un conteneur d'expédition (VBX) préparé au poste d'expédition.
Patent CA-2818328-C (CA)
Inventor: BEISSWENGER PAUL J
IPC: G01N30/72
Filed: 2013-06-10
Granted: 2017-09-05
Abstract: A method for determining the levels of biomarkers, specifically, advanced glycation end products (AGEs) and oxidation products (Ops) in a biological sample such as a plasma ultrafiltrate, is used to determine a patient's risk and/or rate of developing diabetes related nephropathy. The preferred biomarkers to measure include N.epsilon.-(1- carboxyethyl-lysine (CEL), methylglyoxyl-derived hydroimidazolone (MGHI) and N.epsilon.- carboxymethyllysine (CML). Also provided herein is a method of diabetic care which includes determining a diabetic patient's risk of developing diabetes related kidney disease and adjusting the patient's treatment regimen to include in addition to glucose lowering agents, additional treatments such as medications that modify the renin-angiotensin system, or specialized diets with low levels of AGEs or oxidative products.
Patent CA-2819909-C (CA)
Inventor: FICHT REINHOLD
IPC: F16J15/00
Filed: 2011-09-21
Granted: 2016-11-15
Abstract: This relates to an arrangement for sealing off a piston rod, which moves substantially rectilinearly in a reciprocating manner with respect to a passage opening, of a reciprocating-piston machine, having a sealing means which surrounds the piston rod and which is in the form of an internally clamping seal ring which is arranged in the region of the passage opening so as to be substantially positionally fixed with respect to a seal housing, wherein at least two seal rings are provided which are mounted in the seal housing so as to be movable in a radial direction, in particular in a floating fashion, and between at least two seal rings there is arranged a spacer device which, radially at the outside, is guided in the seal housing without play or with a small amount of play and which, radially at the inside, has a radially greater amount of play with respect to the piston rod and does not make contact with the piston rod, in particular is arranged spaced apart from the piston rod, so as to form, together with the seal rings and the piston rod, an accumulation chamber for medium to be sealed off, for example for oil, and the spacer ring has at least one passage for discharging medium out of the accumulation chamber.
Patent CA-2822642-C (CA)
Title: Appareil de prevention des lesions au cou, des lesions a la colonne vertebrale et des commotions
Inventor: JACKSON KEVIN J
IPC: A63B71/10
Filed: 2013-08-01
Granted: 2018-06-05
Abstract: Un appareil destiné à prévenir une blessure au cou, une lésion de la moelle épinière et une commotion cérébrale est décrit. Lappareil comprend un casque, un harnais corporel et une pluralité densembles dancrage reliant le casque au harnais corporel. Les ensembles dancrage sont réglables pour limiter la rotation cervicale, la courbure latérale, la flexion et les plages de mouvement dextension dun utilisateur à un point de réglage prédéterminé. Chaque ensemble dancrage comprend une pluralité de cordes de guidage qui sétendent du casque à un ancrage de lensemble dancrage, la pluralité de cordes de guidage étant fixées à lancrage, mais pouvant être réglées individuellement par rapport à ce dernier.
Patent CA-2828770-C (CA)
Inventor: WARNOCK ROGER P JR
IPC: E21B33/035
Filed: 2012-03-08
Granted: 2017-12-05
Abstract: A subsea pump system is adapted to close a hydraulic ram of a blowout preventer. The subsea pump system has at least a first pump (210) and a second pump (220) configured to pump drive fluid from a source to the hydraulic ram. The system has a controller (230) configured to automatically select at least one of the first and second pumps for pumping the drive fluid wherein at least the first pump(210)is selected at a lower fluid pressure range and at least the second pump(220) is selected at a higher fluid pressure range.A method of operating a pump system and an intervention skid for a pump system are also described.
Patent CA-2829843-C (CA)
Inventor: COLLETT LAURA
IPC: B64D45/00
Filed: 2012-03-16
Granted: 2018-10-16
Abstract: The present invention provides a method and system of determining the ground-to-tyre friction coefficient for an aircraft landing event, the method comprising: providing a plurality of aircraft data parameters including aircraft vertical acceleration to an aircraft computational model and repeatedly modelling the landing event using the aircraft computational model by varying one or more initial conditions of the aircraft model until a best match between a modelled value of aircraft vertical acceleration and the provided value of aircraft vertical acceleration is determined; providing the aircraft computational model initial conditions associated with the best match of modelled and provided aircraft vertical acceleration values to a landing gear computational model and also providing a strain value derived from a first sensor located on the aircraft landing gear to the landing gear computational model, the landing gear computational model having a value for the ground-to-tyre friction coefficient as a variable condition; modelling the landing gear to generate a modelled strain value and comparing the modelled strain value with the measured strain value; and repeating the landing gear modelling step with a different value for the ground-to-tyre friction coefficient until a best match between the modelled strain value and the measured strain value is determined and outputting the respective friction coefficient value.
Patent CA-2834879-C (CA)
Title: Fgfr1 agonists and methods of use
Inventor: SONODA JUNICHIRO
IPC: A61P3/10
Filed: 2012-05-15
Granted: 2019-10-22
Abstract: The disclosure provides FGFR1 agonists, including agonistic anti-FGFRl antibodies, and methods of using the same.
Patent CA-2834956-C (CA)
Inventor: LOZANO-DUBERNARD BERNARDO
IPC: A61P31/14
Filed: 2011-05-07
Granted: 2018-11-20
Abstract: A live or inactivated recombinant vaccine is described, comprising a viral vector and a pharmaceutically acceptable vehicle, adjuvant and/or excipient, wherein the viral vector is capable of generating a cell immune response due to an increased alpha and/or gamma interferon production, and is capable of a quick replication, and it has inserted a nucleotide sequence of the ORF 5 and ORF 6 from PRSS.
Patent CA-2839952-C (CA)
Inventor: BENNETT CHRISTOPHER RYAN
IPC: H04W12/06
Filed: 2012-06-29
Granted: 2018-03-27
Abstract: Des agences établissent de multiples dispositifs pour leur personnel afin de maintenir des identités distinctes pendant la durée d'enquêtes attribuées. Afin de fournir des fonctions flexibles aux agences, un téléphone est transformé en vue d'être utilisé avec de multiples numéros de téléphones rattachés. Par conséquent, un téléphone unique peut être utilisé pour gérer de multiples identités pendant la durée d'une ou de plusieurs enquêtes. Au moyen d'un numéro rattaché à de multiples numéros, un dispositif donné peut lancer et recevoir des appels sur le réseau à des contacts/provenant de contacts. Outre la fourniture de numéros rattachés à de multiples numéros, l'invention permet de surveiller en direct et d'enregistrer des appels au moyen des numéros rattachés à de multiples numéros en vue de l'établissement d'une preuve.
Patent CA-2841178-C (CA)
Inventor: HIPSKIND PHILIP ARTHUR
IPC: A61P35/02
Filed: 2012-07-18
Granted: 2016-12-20
Abstract: The present invention provides a compound, or a pharmaceutically acceptable salt or hydrate, and a pharmaceutical composition containing said compound, or a pharmaceutically acceptable salt or hydrate, useful as a Notch pathway signaling inhibitor for the treatment of cancer
Patent CA-2842760-C (CA)
Title: Expanded polystyrene made using d-limonene as a plasticizer
Inventor: GIBEAULT JEAN-PIERRE
IPC: C08J9/20
Filed: 2014-02-13
Granted: 2021-06-22
Abstract: Abstract of the Disclosure Disclosed is a process for production of expanded polystyrene using D-limonene as a plasticizer, which allows reducing the amount of pentane in the process, yet allows generating beads with similar cell size as if greater quantities of pentane had been used. Pentane is an organic solvent with toxicity associated with organic solvents. The process comprises heating a mixture of styrene, demineralized water, brominated flame retardant chemicals, a peroxide, paraffin, tricalcium phosphate (TCP), a surfactant, an extender and D-limonene, and adding pentane and a polymerization initiator and heating to foun EPS beads. 3945930 Date Recue/Date Received 2020-05-08
Patent CA-2849162-C (CA)
Inventor: FORD DAVID K
IPC: H04L12/16
Filed: 2012-09-20
Granted: 2016-12-20
Abstract: A system, methods, and apparatus for validating communications in an open architecture system are disclosed. In an example embodiment, a method includes selecting transactional information to transmit from a server to a communicatively coupled client device based on a request from the client device, selecting presentation information corresponding to the transactional information to transmit from the server to the client device, transmitting at least one message including the presentation and transactional information from the server to the client device, determining a prediction as to how the client device will render the transactional information based on the presentation information, receiving a response message from the client, and responsive to information in the response message not matching the prediction, providing an indication there is a malicious application affecting communications between the server and the client device.
Patent CA-2849622-C (CA)
Inventor: MEYER HEINZ-ULRICH
IPC: F16L57/00
Filed: 2014-04-23
Granted: 2016-11-15
Abstract: The invention relates to an annularly closable band for encircling one or more articles, having an inner side, which is intended to face the article or articles to be encircled, an outer side located opposite the inner side, and two end regions (4, 5), which are made to overlap one another in order to close the band, wherein the end regions have corresponding closing elements, which are designed to be brought into engagement with one another such that the band has a substantially smooth outer circumferential surface in the closed state. The invention also relates to the use of a corresponding band as a protective cover for a component of a dispensing device, preferably as a protective cover for a breakaway coupling of a dispensing nozzle.
Patent CA-2851784-C (CA)
Inventor: MALONEY JAMES GERARD
IPC: H01H71/02
Filed: 2014-05-14
Granted: 2021-01-12
Abstract: Un ensemble de coupe-circuits et denceintes électriques qui sont configurés pour permettre à une enceinte électrique ayant un courant nominal davoir connecté à celui-ci un coupe-circuit ayant un transport de courant nominal qui nest pas supérieur au courant nominal est décrit. Toutefois, un interrupteur de courant ayant un transport de courant nominal inférieur au courant nominal de lenceinte électrique peut potentiellement être connecté à celui-ci. Un tel équipement dinterruption électrique utilise des goujons filetés sur des barres omnibus de différentes tailles et/ou qui sont séparées par différentes distances afin dempêcher quune enceinte électrique ayant un courant nominal soit électriquement connectée à un coupe-circuit ayant un transport de courant nominal supérieur au courant nominal. En variante ou en outre, le coupe-circuit et/ou lenceinte électrique peuvent avoir des éléments dinterférence qui interfèrent physiquement avec le montage et/ou la connexion électrique dun coupe-circuit ayant un transport de courant nominal avec une enceinte électrique ayant un courant nominal inférieur au transport de courant nominal.
Patent CA-2853046-C (CA)
Title: Dispositif domestique intelligent qui s'auto-qualifie pour fonctionnalite d'etat d'absence
Inventor: FISHER EVAN J
IPC: F24F11/52
Filed: 2012-09-30
Granted: 2020-04-21
Abstract: Selon la présente invention, un thermostat comprend un boîtier et un capteur d'occupation qui est disposé dans le boîtier et configuré pour détecter des présences physiques d'utilisateurs dans une zone réactive du capteur d'occupation. Le thermostat peut également comprendre un système de traitement qui est disposé dans le boîtier et en communication fonctionnelle avec le capteur d'occupation. Le système de traitement peut être configuré pour déterminer, après une période d'essai, s'il faut activer une caractéristique d'état d'absence par stockage d'indications à propos du nombre de fois que le capteur d'occupation a détecté des présences physiques durant la période d'essai, calcul d'un niveau d'occupation pour la période d'essai, comparaison du niveau d'occupation à un critère seuil, détermination si des indications suffisamment vraies de conditions d'occupation ont été détectées par le capteur d'occupation durant la période d'essai, et autorisation de la caractéristique d'état d'absence du thermostat s'il est déterminé que les indications suffisamment vraies de conditions d'occupation ont été détectées durant la période d'essai.
Patent CA-2854746-C (CA)
Inventor: MCELHINNEY GRAHAM ARTHUR
IPC: E21B47/02
Filed: 2014-06-18
Granted: 2018-10-02
Abstract: A method is provided to determine a distance, a direction, or both between an existing first wellbore and at least one sensor module of a drill string within a second wellbore being drilled. The method includes using the at least one sensor module to measure a magnetic field and to generate at least one first signal indicative of the measured magnetic field. The method further includes using the at least one sensor module to gyroscopically measure an azimuth, an inclination, or both of the at least one sensor module and to generate at least one second signal indicative of the measured azimuth, inclination, or both. The method further includes using the at least one first signal and the at least one second signal to calculate a distance between the existing first wellbore and the at least one sensor module, a direction between the existing first wellbore and the at least one sensor module, or both a distance and a direction between the existing first wellbore and the at least one sensor module.
Patent CA-2858102-C (CA)
Title: Detection and quantification of nucleic acid to assess microbial biomass in paper defects and machine felts
Inventor: RICE LAURA E
IPC: C12N15/11
Filed: 2013-01-24
Granted: 2021-04-06
Abstract: The invention is directed towards methods and compositions for identifying the specific microorganisms present in a particular potion of a papermaking processes. The method involves obtaining a sample from the process which is such that little or no live examples of the microorganism remain. However because DNA from the organisms is still present, an analysis which identifies portions of DNA specific to the particular organism will correctly identify the microorganism present. This allows for analysis of infestations present on felts or paper sheets which typically no longer have many live microorganisms on them when samples are taken for analysis.
Patent CA-2859396-C (CA)
Inventor: ZHOU SHAOHUA
IPC: E21B43/26
Filed: 2012-12-19
Granted: 2016-12-06
Abstract: A system 20 for a drilling and fracturing a wellbore 22 in a single trip includes a drill string 26, drill bit 40, and a fluid flow means for delivering fluid through the string and drill bit 40. The drill bit 40 includes a body with cutting blades 42. and nozzles 46 between the cutting blades 42 for washing away drilling generated cuttings. A packer 62 on the drill bit 40 selectively seals with an inner surface of the wellbore 22 to form a space 64. Deploying the packer 62 at a designated spot in the wellbore 22 defines a fracturing zone Z in the wellbore 22. Closing the nozzles 46 while opening side ports on the body, delivers fracturing fluid into the space 64, A pressurizing system 20 can be included to pressurize the fluid so that pressure in the space 64 overcomes the formation strength and fractures the formation adjacent the enclosed space 64. The packer 62 can be released, drilling can resume, and fracturing can occur at a different depth in the wellbore 22.