baber/WOPTO huggingface dataset:
Patent EA-005820-B1 (EA)
Title: Agonists and antagonists of 5-ht2c receptors
Inventor: NILSSON BJORN
IPC: A61P25/28
Filed: 2000-05-19
Abstract: The invention relates to compounds of general formula (Ib) wherein: X1 is -O-, -S- or -N(R27)-; Y1 is -O-, -S- or -N(R27)- or -CH2 ; Ra C3-8 cycloalkyl, monocyclic or bicyclic aryl having from 6 to 10 carbon atoms in ring(s), wherein only one ring is aromatic, and one or several atoms in ring(s) are other than carbon and selected from nitrogen, sulfur, oxygen, and selenium, wherein each of said cycloalkyl, aryl and heteroaryl may be optionally substituted in one or several positions; R20 and R21 independently of each other are hydrogen, halogen or C1-4-alkyl; or wherein R20 and R21 together with the carbon atoms to which they are bound form benzene to form a quinoxaline ring or thiophene to form a thieno[3,4-b]pyrazine ring, optionally mono- or disubstituted by halogen; R22 is hydrogen, hydroxy, C1-4-alkyl or C1-4-alkoxycarbonyl; R23 and R24 independently of each other are hydrogen, C1-4-alkyl; R25 is hydrogen or C1-4-alkyl; R26 is hydrogen, C1-4-alkyl or is linked to a carbon atom in Ra adjacent to the atom binding to Y1 to form a 5- or 6-membered ring which may contain 0, 1 or 2 heteroatoms, wherein said ring is optionally substituted with methyl; R27 is hydrogen or C1-4-alkyl, preferably methyl or ethyl; and y and z independently of each other are 1 or 2, and pharmaceutically acceptable salts, hydrates and prodrug forms thereof. The compounds may be prepared by per se conventional methods. The proposed new compounds are bound with 5-HT2C receptors as agonists and antagonists and can be used for treating a human or animal subject suffering from a serotonin-related disorder, such as eating disorders, especially obesity, memory disorders, schizophrenia, mood disorders, anxiety disorders, pain, sexual dysfunctions, and urinary disorders.
Patent EA-005821-B1 (EA)
Title: Immunomodulatory peptides derived from heat shock proteins and uses thereof
Inventor: MARTINI ALBERTO
IPC: C07K14/245
Filed: 2001-10-31
Abstract: A method of modulating an immune response in a subject is disclosed. The invention is based on the discovery that an effective therapeutic strategy for ameliorating the inflammation-related symptoms of an immune-mediated disease, such as arthritis, can be achieved by modulation of the underlying immune response itself, rather than by merely addressing the resulting inflammation. This strategy can be used to regulate the inflammatory response and is applicable to a variety of contexts in which immune modulation is desired, such as mucosal tolerization, DNA vaccination, anergy induction, active immunization, and ex vivo modulation of antigen-specific T cells. In one embodiment, the method comprises administering to the subject a bacterial dnaJ peptide or a human homolog or a non-homologous human isoform thereof.
Patent EA-006915-B1 (EA)
Title: Reinforcing device for bushing used to produce filaments, such as glass-based filaments
Inventor: RENAUDIN JEAN-PIERRE
IPC: C03B37/083
Filed: 2004-02-04
Abstract: The invention relates to a reinforcing device (1) which is intended, for example, for a bushing base comprising numerous holes through which filaments, such as glass filaments, are drawn. The inventive device consists of a reinforcing part (10) comprising a first hollow part (12) which defines at least one housing and a second part (13) which extends at least partially along the length of the hollow part (12), as well as at least one stiffener element (40) which is inserted into the housing of said hollow part. The invention is characterised in that the section of the stiffener element (40) is essentially identical to the inner section of the hollow part (12).
Patent EA-009173-B1 (EA)
Title: Preparation of silicate or glass in a furnace with burners immersed in a reducing medium
Inventor: JACQUES REMI
IPC: C01B33/20
Filed: 2004-09-07
Abstract: The invention relates to a method for the preparation of silicates of an element, selected from amongst the alkaline, alkaline earth or rare earth elements, comprising a reaction between silica and the sulphate of said element in a reactor provided with at least one burner immersed in a fused mass, said immersed burner being supplied with a gas comprising oxygen, whereby an excess of reducing fuel is introduced into the reactor with relation to the oxygen effectively consumed. The method permits the satisfactory execution of the method at a relatively low temperature.
Patent EA-011155-B1 (EA)
Title: Phenylpyridinylpiperazin derivatives, the process to make them and the pharmaceutical composition containing them
Inventor: DESO PATRICE
IPC: A61K31/496
Filed: 2006-05-12
Abstract: There proposed compounds of formula (I):wherein:X represents a C(O) or SOgroup,Rrepresents: a phenyl group,or an NRRgroup, wherein Rand R, which may be the same or different, each independently represent a hydrogen atom, a linear or branched (C-C)alkyl group, or a (C-C)cycloalkyl group,or Rand R, together with the nitrogen atom carrying them, form a 5- to 8-membered ring wherein one of the carbon atoms may be replaced by a nitrogen, oxygen or sulphur atom or by an SO or SOgroup, wherein the ring thereby defined is optionally bridged by a linear or branched (C-C)alkyl group and is optionally substituted by one or more identical or different groups selected from halogen, linear or branched (C-C)alkyl group, (C-C)cycloalkyl group, hydroxy, oxo and an amino group (optionally substituted by one or more linear or branched (C-C)alkyl groups),Rrepresents a linear or branched (C-C)alkyl group or a (C-C)cycloalkyl group,their enantiomers and diastereoisomers, acid and base addition salts, and also a process to make them and pharmaceutical compositions containing compounds of formula (I).
Patent EA-011621-B1 (EA)
Title: Adjusted heating device for boiler
Inventor: ROQUES BERNARD
IPC: F24H1/20
Filed: 2007-02-13
Abstract: A device for heating and regulating water temperature in a ballon (8) for hot water contained in a water tank (7) and according to the proposed invention the device comprises, on one side, a base (2) made of heat-conducting material and rigidly connected tightly to a heating resistance and to a regulating temperature probe (4), wherein the heat-conducting base (2) provided with fixation means (6) permitting to retain tightly the heater (1) for heating and regulating temperature in the bottom part of the tank (7) of the ballon, and, to the side, an insulated housing (5) mounted on the base and containing guides and fixings for electrical connections so that the latter are never in direct contact with the heat conducting base.
Patent EA-010227-B1 (EA)
Title: Foodstuff imitating pieces of natural meat flesh and method for preparing thereof
Inventor: PESKIN ALEXANDER VLADIMIROVICH
IPC: A23L13/60
Filed: 2007-03-29
Abstract: The present invention relates to meat-processing industry, particular to meat products intended for food, primarily of domestic animals. e.g. cats and dogs or other animals, ration of which includes natural meat, more particular, to a foodstuff imitating pieces of natural meat, and to a method for preparing thereof. According to the present invention a foodstuff is disclosed imitating pieces of natural meat flesh, one of surfaces of each meat piece has evidently expressed structure similar to a structure of transversal striated muscle fiber of natural meat. A method for preparing said foodstuff is also disclosed.
Patent EA-012321-B1 (EA)
Title: An insulation element for fitting between elongated members in a framework of a building structure
Inventor: JEPSEN FLEMMING
IPC: E04D13/16
Filed: 2006-09-19
Abstract: The present invention concerns substantially a rectangular insulation element (1) for fitting between elongated members (2) in a framework of a building structure, such as between rafters, beams or the like, said insulation element (1) has substantially parallel first and second sides and substantially parallel third and fourth sides, and also has a first side portion and a substantially parallel opposing second side portion, wherein at least said first side portion is provided with a trim portion (3) with an elongated trim section along the first side, and said trim section has a predetermined width. At least said second side portion is provided with a flexible zone (4) extending along the second side comprising a flexible section (4, 6) with a predetermined width (d) in the insulation element (1). The proposed insulation element is suitable for fitting within a wide range in the distance between elongated members in the building framework.
Patent EA-020155-B1 (EA)
Title: Propulsor
Inventor: POSVENCHUK IVAN ALEXANDROVICH
IPC: B63H1/02
Filed: 2009-11-12
Abstract: The invention relates to machine building, in particular, to a propulsor converting rotational motion of a working body to a thrust force and can be used in ground, water and air transport. A propulsor comprises a drive shaft with working blades mounted in the body made in the form of a hollow truncated cone (disc) having an input in a lesser base for inputting and/or intaking the working body, wherein in the greater base an output and a cylindrical part, in which stationary brake vanes are fastened sequentially and an additional disc mounted behind the working blades having the diameter less than the output, thus forming an annular gap.
Patent EA-024007-B1 (EA)
Title: Systems and method for displaying attitude information associated with an airship
Inventor: BALASKOVIC PIERRE
IPC: B64B1/36
Filed: 2008-08-07
Abstract: A system for controlling yaw associated with an airship may include one or more vertical control surfaces associated with the airship, a first power source and a second power source, each configured to provide a thrust associated with the airship, and a yaw control configured to receive an input indicative of a desired yaw angle. The system may further include a controller communicatively connected to the yaw control, the one or more vertical control surfaces, and the first and second power sources. The controller may be configured to receive an output signal from the yaw control corresponding to the desired yaw angle and to generate a control signal configured to modify a state associated with at least one of the one or more vertical control surfaces, the first power source, and the second power source, such that the airship substantially attains the desired yaw angle.
Patent EA-019488-B1 (EA)
Title: Limk2 inhibitors and methods of their use
Inventor: BURGOON HUGH ALFRED
IPC: A61P27/02
Filed: 2009-04-20
Abstract: Inhibitors of LIM kinase 2 are disclosed and methods of their use. Particular compounds are of the formula (I).
Patent EA-018904-B1 (EA)
Title: Method and device for calcinating phosphorous plaster
Inventor: GOECKE VOLKER
IPC: C04B11/26
Filed: 2009-05-11
Abstract: The invention relates to a method for calcinating phosphorous plaster or other humid synthetic plasters. Said method consists of two steps, the plaster is calcinated in a calcinator (3) and the hot product is post-calcinated in a post reactor (6). According to the invention, fine comminution is combined with the post-calcination in the post-reactor (6) and humid gas is added to the product. The invention also relates to a device for carrying out said method and a corresponding retrofitted reactor.
Patent EA-023754-B1 (EA)
Title: Herbicidal benzoxazinones
Inventor: WITSCHEL MATTHIAS
IPC: C07D413/04
Filed: 2010-06-11
Abstract: The present invention relates to benzoxazinones of the general formula Iwherein the variables are defined according to the description, processes and intermediates for preparing the benzoxazinones of the formula I, compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one benzoxazinones of the formula I to act on plants, their seed and/or their habitat.
Patent EA-020723-B1 (EA)
Title: Method for combining connection components with polypropylene pipe pp-r
Inventor: TOPALYAN AKSEL
IPC: F16L9/147
Filed: 2010-12-03
Abstract: The invention relates to the method of combination of the connection components with the intermediate aluminium foil layer (2) polypropylene pipe (5) (PP-R) comprising the operations steps of cutting the pipe (5) vertical to its axis; placeing the screw plate (12) and the connection piece screw plate into the welding machine and heating up to 260°C; marking the welding length and after heating the welding machine up to 260°C pushing the polypropylene pipe (5) (PP-R) up to the marked welding point, comprising the intermediate aluminium foil layer (2), into the screw plate (12) at the same time and force with pushing the connection piece towards the connection piece screw plate up to the marked point; and it is characterized in that it comprises the operation steps of melting the surface of the PP-R outer layer (3) by its contacting with the outer layer melting surface (9), which guides the said outer layer (3), when pushing the PP-R pipe (5) into the heated screw plate (12); melting the PP-R inner layer (1) by its contacting with the inner layer melting surface (10), which guides the said inner layer (1), when pushing the PP-R pipe (5) into the heated screw plate (12), when the pipe (5) reaches towards the end, flowing the melted parts at the outer layer (3) and the inner layer (1) towards the section surface of the pipe (5) with the help of the screw plate (12), comprising the guide cavity (7); covering the said foil layer (2) by combination of the PP-R outer and inner layers (1, 3) with each other.
Patent EA-026023-B1 (EA)
Title: Detergent composition comprising glutamic-n,n-diacetate, water and bleaching agent
Inventor: VAN DEURZEN MARIA PETRA JOHANNA
IPC: C11D3/33
Filed: 2012-12-10
Abstract: One aspect of the invention relates to a detergent composition comprising 20-99.7 wt.% of a continuous phase containing glutamic-N,N-diacetate (GLDA), water and optionally other components; and 0.3-80 wt.% of a dispersed phase comprising at least 0.3% of bleach particles by weight of the composition, said bleach particles having a particle size of at least 10 μm, wherein the continuous phase contains at least 10 wt.% of GLDA and at least 10 wt.% of water and wherein the weight ratio of GLDA to water lies within the range of 5:6 to 5:1. Despite the high water content, the present bleach containing detergent composition is storage stable and retains bleach activity for a prolonged period of time. The invention also provides a process of preparing a liquid base for a detergent composition comprising GLDA and water in a weight ratio of GLDA to water of 5:6 to 5:1, said process comprising combining 100 parts by weight of a liquid mixture of GLDA and water with 10-300 parts by weight of GLDA powder, said liquid mixture containing 20-50 wt.% of GLDA and 50-80 wt.% water and said GLDA powder containing at least 65 wt.% GLDA.
Patent EA-029186-B1 (EA)
Title: Protective mark
Inventor: VASILIEV ALEKSEY GERMANOVICH
IPC: G02B5/30
Filed: 2015-02-26
Abstract: Disclosed is a protective mark having a layer with a concealed polarisation image and a reflecting layer, wherein the layer with the concealed polarisation image has isotropic and anisotropic regions, the layer with the concealed polarisation image has phase polarisation capability and represents a quarter-wave plate. The technical result achieved is increasing level of protection against counterfeit by imitation and copying while providing a cheap and reliable method of authenticating marked articles.
Patent EA-036030-B1 (EA)
Title: Immunogenic vaccine against hbv in a human
Inventor: WEINER DAVID B
IPC: C12N15/63
Filed: 2013-09-19
Abstract: The invention relates to nucleic acid sequences encoding an HBV full length consensus surface antigen protein and to vaccines thereof for inducing an immune response against HBV in a human, and, based on the use thereof, to methods of inducing an immune response against HBV in a human, methods of protecting a human from HBV infection and methods of treatment thereof in a human.
Patent EA-030823-B1 (EA)
Title: [1,2,4]TRIAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS PROTOZOAN PROTEASOME INHIBITORS FOR THE TREATMENT OF A PARASITIC DISEASE SUCH AS LEISHMANIASIS
Inventor: BIGGART AGNES
IPC: C07D487/04
Filed: 2014-12-18
Abstract: The present invention relates to compounds of Formula Aor a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein the variables are as defined herein. The present invention further relates to pharmaceutical compositions comprising said compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating or eradicating the pathology and/or symptomology of a disease caused by a parasite, such as leishmaniasis, human African trypanosomiasis and Chagas disease.
Patent EA-036012-B1 (EA)
Title: Systems and methods for reducing undesired eddy currents
Inventor: RATH NIKOLAUS
IPC: G21B1/05
Filed: 2016-05-09
Abstract: Systems and methods to reduce the amplitude of undesirable eddy currents in conducting structures, e.g., induced by the translation of an FRC into a confinement chamber, while leaving beneficial eddy currents unaffected. This is achieved by inducing opposing currents in the same conducting structures prior to plasma translation into the confinement chamber.
Patent EA-034817-B1 (EA)
Title: Method of selective determination of heavy metal ions in aqueous media using luminescent multi-probe system
Inventor: MELNIKOV ANDREY GENNADIEVICH
IPC: G01N21/64
Filed: 2018-02-27
Abstract: The invention discloses a method of selective determination. A distinctive feature of this method is the use of a luminescent multi-probe system, in which fluorescence spectrum changes in different ways in the presence of various ions. The changes in the fluorescence intensity of various probes belonging to the multi-probe system at wavelengths corresponding to the maxima of the spectrum form a vector signal of the multi-probe system. After calibrating this vector signal against the effects of the required heavy metal ions, it is processed by pattern recognition techniques and saved to a calibration database after processing. The analysis of ionic composition of an unknown test solution is performed by the same procedure as used to retrieve the calibration data. The obtained test signals are compared with the calibration ones to make decision on on the type and concentration of ions present in the unknown test solution. The technical result of the claimed invention consists in the possibility of effective recognition of the types of heavy metal ions in a solution.
Patent EA-036951-B1 (EA)
Title: Liquid polymer delivery system for extended administration of drugs
Inventor: DOWNING JOHN MILTON
IPC: A61P5/26
Filed: 2016-08-03
Abstract: Liquid polymer pharmaceutical compositions with a biodegradable liquid polyester that has a carboxylic acid end group, a biocompatible solvent, and an active pharmaceutical agent are useful for administration into the body to provide extended long term release of the drug.
Patent ES-2213411-B1 (ES)
Title: Sistema sensor optico para medida de nivel en entornos criticos.
Inventor: VAZQUEZ GARCIA CARMEN
IPC: G01F23/292
Filed: 2000-08-09
Granted: 2006-04-01
Abstract: La invención se refiere a un sistema sensor óptico para medida de nivel que consiste en una cabeza transductora (1), enlaces de fibra óptica (21,22), un bloque transmisor/receptor de adquisición/procesado (3) y un bloque de monitorización (4). De la cabeza transductora sale un haz luminoso que se refleja en la superficie del medio cuyo nivel se desea medir. La señal luminosa reflejada posee información dependiente de la distancia recorrida por el haz, permitiendo la medida continua del nivel. El sistema es escalable, pudiendo medir simultáneamente el nivel en distintos puntos o tanques y es compatible con un enlace de alta capacidad. El sistema, sin despreciar otras aplicaciones, mide el nivel en depósitos, en el sector del automóvil, aeroespacial, energético, alimenticio y en todo sector industrial en el que se utilicen tanques de almacenamiento; trabajando eficientemente en entornos extremos: inflamables, elevadas temperaturas, contaminación electromagnética, alta radiación, requerimientos de peso reducido, permitiendo un control remoto.
Patent ES-2188385-B1 (ES)
Inventor: TRILLAS GAY MARIA ISABEL
IPC: A01N63/38
Filed: 2001-06-26
Granted: 2004-12-01
Abstract: The strain of Trichoderma asperellum T34(2) CECT No. 20417 is useful for preparing substrates for biological control of vascular fusariose and death of plants caused by Rhizoctonia solani. The substrates can be peats, composts (hardwood compost, pine bark compost, cork compost, sludge compost from sewage treatment plants, garden residues, etc.) or formulations based on CPV-type compost (compost + peat + vermiculite). The fact that said substrates suppress both Fusarium oxysporum f. sp. lycopersici and Rhizoctonia solani provides an advantage in comparison with other substrates known in prior art. Another advantage is that the use of methyl bromide, a highly harmful product for the environment, in the control of vascular fusariose is avoided.
Patent ES-2188420-B1 (ES)
Title: Dispositivo de visualizacion de impresiones realizadas con tintas de respuesta visible bajo radiacion ultravioleta.
Inventor: ALBA ORBEGOZO IGNACIO
IPC: G07D7/12
Filed: 2001-12-03
Granted: 2004-12-16
Abstract: Dispositivo de visualización de impresiones realizadas con tintas de respuesta visible bajo radiación ultravioleta. Se caracteriza porque comprende medios que obtienen radiación ultravioleta a partir de la radiación solar, para permitir la visualización. Estos medios se materializan en una cámara oscura (1) en la que se aloja la superficie que contiene la impresión con tinta de respuesta visible bajo radiación ultravioleta, y que comprende una ventana (2) cubierta por un filtro (3) en el que al incidir la radiación solar (8) únicamente deja pasar la radiación ultravioleta (9) al interior de la cámara oscura (1), contando ésta además con una abertura (7) de salida de la radiación visible (11) para permitir su visualización a través de dicha abertura.
Patent ES-2219148-B1 (ES)
Title: Metodo y disposicion para un procedimiento de soldadura exento de martensita.
Inventor: PETTERSEN OLA
IPC: B23K3/04
Filed: 2002-05-16
Granted: 2006-06-01
Abstract: Método y disposición para un procedimiento de soldadura exento de martensita en particular para soldar una pieza de conexión, de material eléctricamente conductor, por ejemplo de metal, a una superficie metálica por medio de un nuevo tipo de soldadura de temperatura controlada, por lo que, para ciertos tipos de material, por ejemplo acero, se obtiene una soldadura exenta de martensita, es decir, una soldadura sin cambios estructurales perjudiciales (formación de martensita). Se obtiene una soldadura que está completamente exenta de martensita por debajo de la junta soldada en, por ejemplo, una vía de ferrocarril y/o tubería. La invención se refiere también a una disposición para realizar el citado método.