baber/WOPTO huggingface dataset:
Patent NZ-220290-A (NZ)
Title: Palladium-containing catalyst and carbon monoxide/olefin copolymerisation process
Inventor: VAN BROEKHOVEN J A M
IPC: C08G67/02
Filed: 1987-05-13
Abstract: Novel catalyst composition, characterized in that they are based upon   a) a palladium compound, b) an anion of an acid with a pKa of less than 2, with the proviso that the acid is not a hydrohalogenic acid, c) a bisphosphine of the general formula R1R2P-R-PR3R4. wherein R1-R4 are similar or dissimilar hydrocarbyl groups which may or may not be substituted with polar groups, with the proviso that at least one of the groups R1-R4 represents a polarly substituted aryl group containing at least one polar substituent on a position ortho to phosphorus, and wherein R represents a bivalent organic bridging group containing at least two carbon atoms in the bridge, and d) optionally, a quinone.
Patent NZ-223164-A (NZ)
Title: Therapeutic system for sparingly soluble active ingredients and a process for prearation thereof
Inventor: KHANNA S C
IPC: A61K9/22
Filed: 1988-01-12
Abstract: A therapeutic system to be administered orally and acting systemically having a chamber containing active ingredient, which contains in this chamber slightly soluble active ingredients, swelling agents and, if desired, water-soluble substances for producing an osmotic pressure.
Patent NZ-223599-A (NZ)
Title: Process for encapsulating biologically active substances in multivesicular liposomes, and such liposomes as medicaments
Inventor: HOWELL STEPHEN BARNARD
IPC: A61K9/50
Filed: 1988-02-23
Abstract: Disclosed are large multivesicular liposomes containing biologically active substances, the multivesicular liposomes having defined size distribution, adjustable average size, adjustable internal chamber size and number, and having substantially higher encapsulation efficiency and substantially slower leakage rate of the biologically active substance than in the previous art. The process comprises dissolving a lipid component in volatile organic solvents, adding an immiscible aqueous component containing a hydrochloride and one or more biologically active substances to be encapsulated, making a water-in-oil emulsion from the two components, immersing the emulsion into a second aqueous component, dividing the emulsion into small solvent spherules which contain even smaller aqueous chambers, and then evaporating the solvents to give an aqueous suspension of multivesicular liposomes encapsulating biologically active substances.
Patent NZ-227059-A (NZ)
Title: Mammalian interleukin-1 receptors (il-1r), dna sequences encoding them and cdna clones therefor
Inventor: DOWER STEVEN K
IPC: C07K16/00
Filed: 1988-11-23
Abstract: Mammalian Interleukin-1 receptor proteins (IL-1Rs), DNAs and expression vectors encoding mammalian IL-1Rs, and processes for producing mammalian IL-1Rs as products of cell culture, including recombinant systems, are disclosed.
Patent NZ-234424-A (NZ)
Title: Electronic clinical thermometer having a soft resilient cover
Inventor: ZARAGOZA ROBERT
IPC: G01K13/00
Filed: 1990-07-10
Abstract: A thermometer (20) for measuring the temperature of a living being comprises a housing (21) having a hollow probe (22) extending outwardly therefrom in a distal direction and a temperature sensing element (25) located at the distal end of the probe (22). The housing (21) holds a digital display (31) and electrical means in electrical communication with the temperature sensing element (25) for converting the temperature measured by the temperature sensing element (25) into a readout on the display element (31). A resilient soft cover (43) covers the probe (22) and a portion of the housing (21) to form a gripping surface for the user while allowing visualization of the display element (31). The resilient cover (43) is softer than the probe (22).
Patent NZ-237567-A (NZ)
Title: Substituted indolizidine and quinolizidine derivatives, preparation and pharmaceutical compositions thereof
Inventor: LUI SAIHO PAUL
IPC: C07D455/02
Filed: 1991-03-25
Abstract: The present invention describes a group of polyhydroxylated indolizidines and quinolizidines and their esters. These compounds are prepared starting from 2,6-dideoxy-2,6-imino-1,3,4,5-tetrakis-O-(phenylmethyl)-D-glycero-L-gu lo-heptitol or a corresponding N-substituted compound. The compounds are useful in the treatment of diabetes and as  alpha -glucosidase I inhibitors.
Patent NZ-238551-A (NZ)
Title: Water barrier consisting of swellable clay sandwiched between fabric layers
Inventor: WHITE ALEC W
IPC: D04H5/02
Filed: 1991-06-14
Abstract: There is disclosed a waterproofing material comprising an intermediate layer of a granular abrasive material (16) e.g.a water-swellable colloidal clay, such as bentonite, sandwiched between two layers (12, 14) of flexible sheet or fabric material wherein the two flexible layers of sheet or fabric material are structurally interconnected through the intermediate layer, such as by needle punching, after lubrication of the clay or sheet material with a liquid, such as water, to interconnect fibres of one fabric layer to the other fabric layer at spaced locations over essentially the entire inner surface areas of both sheet or fabric material layers. <IMAGE>
Patent NZ-241294-A (NZ)
Title: Polyamino phenols and their use as radioprotective agents
Inventor: EDWARDS MICHAEL LOUIS
IPC: G21F/
Filed: 1992-01-14
Abstract: The present invention relates to certain polyamine phenols which are useful as radioprotective agents.
Patent NZ-247939-A (NZ)
Title: Stereoselective glycosylation process for the preparation of a beta anomer enriched nucleoside
Inventor: CHOU TA-SEN
IPC: C07H19/14
Filed: 1993-06-21
Abstract: A stereoselective glycosylation process for preparing  beta  anomer fluoronucleosides via the SN2 displacement of an anomeric sulfonyloxy group of an  alpha anomer enriched fluorocarbohydrate with a nucleobase.
Patent NZ-272728-A (NZ)
Title: Quick cook pasta; shape is tubular with inner partial spokes
Inventor: HAUSER THOMAS WILHELM
IPC: A23L7/109
Filed: 1995-08-07
Abstract: A quick cooking pasta (2) is longitudinal and tubular in shape. In cross section the pasta walls are 0.6-1.1 mm thick and it has teeth (1) on its inner surface, running parallel along the length of the tube. The teeth have a height of 0.3-1.6mm and height to width ratio of 0.4-2.0.
Patent NZ-286599-A (NZ)
Title: use of protein antibody conjugate for stimulating an immune response
Inventor: MURRAY BRENDAN
IPC: A61K39/39
Filed: 1995-03-17
Abstract: The use of a soluble non-aggregated carrier protein antibody conjugate in the manufacture of a medicament is for evoking an immune response in a mammal wherein one or more carrier protein molecules are site selectively and covalently linked to the constant region part of one antibody molecule.
Patent NZ-304859-A (NZ)
Title: 4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives, medicaments and processes for the preparation thereof
Inventor: TRAXLER PETER
IPC: C07D231/38
Filed: 1996-03-22
Abstract: -Amino-1H-pyrazolo[3,4-d]pyrimidine derivatives of formula (I) wherein the symbols are as defined in the specification, and intermediates for their manufacture are described.  The compounds of formula (I) inhibit especially the tyrosine kinase activity of the receptor for epidermal growth factor and can be used, for example, in the case of epidermal hyperproliferation (psoriasis) and as anti-tumour agents.
Patent NZ-332484-A (NZ)
Title: use of pyridyl and pyrimidyl substituted piperazine derivatives for treating substance abuse disorders
Inventor: BJORK ANDERS
IPC: A61K31/5377
Filed: 1997-04-22
Abstract: Pyridyl and pyrimidyl substituted piperazine derivatives of formula I or pharmaceutically acceptable salts thereof are used in the manufacture of a medicament for the relief or prevention of a withdrawal syndrome resulting from addiction to a drug or substance or abuse and/or for the suppression of dependence on drugs or substances of abuse. In formula I: R1 is halogen or hydrogen; R2 is halogen; X is CH2, O or S; R3 and R4 are independently hydrogen or alkyl; A is a group of formula II R5 is hydrogen, alkyl or halogen; R6 and R7 are independently hydrogen, alkyl, halogen, alkoxy, hydroxy, nitro, trifluoromethyl, COOR8, CONR9R10 or COB; R8 is hydrogen or alkyl; R9 and R10 are independently hydrogen, alkyl or cycloalkyl; B is a group of formula III; m is 1 to 4; R11 is hydrogen or alkyl.
Patent NZ-333609-A (NZ)
Title: Peptide inhibitors of the interaction between P35 and MDM2 and the treatment of tumor cells
Inventor: LANE DAVID
IPC: C07K14/82
Filed: 1997-07-04
Abstract: Peptides of the formula R1-X-F-X-R2-R3-W-X-X-R4, wherein R1 is proline, leucine, glutamic acid, cystine or glutamine, X is any naturally occurring amino acid, R2 is arginine, histidine, glutamic acid, cystine serine or aspartic acid, R3 is histidine, phenylalanine or tyrosine, R4 is phenylalanine, glutamine or leucine, F is phenylalanine and W is tryptophan. These peptides are capable of binding to the oncogene protein MDM2 and are used in the manufacture of medicaments for inhibiting the growth of tumor cells by interfering with the interaction between human p53 and human MDM2.
Patent NZ-502786-A (NZ)
Title: Preparation of gabapentin analogues comprised of adding cyclohexanone to sodium hydride and finally heating the formed lactam in HCl and dioxan
Inventor: BRYANS JUSTIN STEPHEN
IPC: C07B53/00
Filed: 1998-08-11
Abstract: A process for preparing a compound of the Formula (I) comprising: a) adding cyclohexanone to a mixture of sodium hydride suspended in dry tetrahydrofuran to which triethyl phosphonoacetate was added; b) partitioning the mixture between HCl and diethyl ether and collecting the ether layer; c) dissolving the product of step (b) the a,b-unsaturated ester in THF with nitromethane and tetrabutylammonium fluoride and heating the resulting mixture to produce a nitro ester; d) dissolving the product of step (c) a nitro ester in methanol and shaking in the presence of H2 over a catalyst to produce the corresponding lactam; and e) heating the product of step (d) a lactam, to reflux in a mixture of HCl and dioxan to produce a compound of the Formula (I), and converting, if desired, to a pharmaceutically acceptable salt.
Patent NZ-507199-A (NZ)
Title: Crystalline forms of 1S-[1alpha(2S*,3R*), 9ALPHA]-6, 10-dioxo-N(2-ethoxy-5-oxo-tetrahydro-3-furanyl) -9-[[(1-isoquinolyl) carbonyl]-amino] octahydro-6H-piridazino[1,2-A][1,2] diazepin- 1-carboxamide
Inventor: GODARD JEAN-YVES
IPC: A61P25/00
Filed: 1999-04-07
Abstract: A crystalline form of anhydrous 1S-[1alpha(2S*,3R*), 9ALPHA]-6, 10-dioxo-N(2-ethoxy-5-oxo-tetrahydro-3-furanyl)-9-[[(1-isoquinolyl) carbonyl]-amino] octahydro-6H-piridazino[1,2-A][1,2] diazepin-1-carboxamide which doesn't have the drawbacks of the currently known amorphous form of said compound; and a process for its preparation.
Patent NZ-507346-A (NZ)
Title: An automated animal handling apparatus consisting of at least two panels which is triggered when an animal enters the chute
Inventor: FAGAN CAROL ANN
IPC: A01K15/04
Filed: 2000-10-05
Abstract: An animal handling device, including at least two side panels (3, 6), and at least one securing device, and at least one power device (7), and at least one sensor (2) system. The device is characterised in that on the triggering of a sensor (2), the power device (7) activates the securing device so as to secure the animal (4) in a desired position.
Patent NZ-509717-A (NZ)
Title: Nail plate with teeth on one portion and nail holes on another portion for joining two truss members
Inventor: OLDEN MARC
IPC: F16B15/00
Filed: 2001-02-02
Abstract: Connector 61 or 71 has a first plate portion with integral nailing teeth and a second plate portion without such nailing teeth but with nailing holes. This allows a truss to be collapsed, transported to site and erected on site.
Patent NZ-512302-A (NZ)
Title: Method to produce inactivated w/o emulsion adjuvated vaccines
Inventor: SCHRIER CARLA CHRISTINA
IPC: A61P37/04
Filed: 1999-12-15
Abstract: Method for preparing an inactivated, water-in-oil emulsion, adjuvated vaccine.  Said method comprising mixing an aqueous solution comprising one or more inactivated antigens under mild conditions with a ready-made water-in-oil emulsion.  Said antigens can be selected from the group comprising inactivated Newcastle Disease Virus (NDV), Infectious Bursal Disease Virus (IBDV), Infectious Bronchitis Virus (IBV), or immunogenic subunits thereof. Also covered is a kit that can be used for the preparation of said vaccine, comprising at least one dosage of inactivated antigen and a separate dosage of water-in-oil emulsion.
Patent NZ-513149-A (NZ)
Title: Inking system with a belt and differential roller speeds
Inventor: WHELAN EDWARD J
IPC: B41F31/16
Filed: 1999-10-27
Abstract: To minimize the presence of roll-to-roll nips in an inking system for a printing plate cylinder, an ink transfer belt (80) transfers ink from an ink transfer roller (14), which receives ink from a supply (12), to the ink receiving elements on a printing plate cylinder (50). A plurality of guide rolls (84) inside the loop of the ink transfer belt (80) contact the drivable surface of that belt. A drive (not shown) is connected with one of the guide rollers (84) for driving it to rotate at a first velocity, which is the velocity of the ink transfer roll and of the printing plate cylinder. An ink distribution roller (70) is disposed outside the loop of the belt in contact with the opposite, ink transfer surface of the belt and between the ink transfer roller and the printing plate cylinder.
Patent NZ-513388-A (NZ)
Title: Treatment using multi-subtype FIV vaccines
Inventor: YAMAMOTO JANET K
IPC: C12N5/0783
Filed: 1996-08-23
Abstract: A method for inducing a protective immune response against FIV infection in a non-human animal susceptible to FlY infection, comprising administering to said animal an effective amount of a vaccine composition comprising an FlY immunogen, wherein said FlY immunogen comprises an immunogen or immunogens derived from or comprising at least two different FlY strains of different FlY subtypes, wherein said vaccine composition is capable of eliciting an immune response against a plurality of FlY subtypes and strains of FlY homologous and heterologous to said FIV strains of said FlY immunogen.
Patent NZ-514967-A (NZ)
Title: Sealing disc and film composite for a closure of a container
Inventor: WIENING HEINZ-RUDOLF
IPC: B65D77/20
Filed: 2000-05-03
Abstract: Disclosed is a film composite which serves as a closure for  use  with a container (10) having an opening (11)  that is  delimited by a peripheral edge. The film composite  (30) is  comprised of several layers. An adhesive layer  (32)  is arranged  between  both of the top two layers  (31,  33)  at least  over  a  partial  surface. The uppermost  layer  (33) comprises an upwardly projecting fold (40).
Patent NZ-515097-A (NZ)
Title: Improvements in and relating to bio-degradable foamed products
Inventor: HORNSEY ANYA JANE
IPC: B29C35/08
Filed: 2001-10-29
Abstract: A method of producing a bio-degradable foamed product with a finished foam thickness of up to 1 metre and a foam surface suitable for packaging applications, comprising placing a bio-degradable raw material into a mould then placing the mould into a microwave cavity wherein the cavity includes a selection of magnetrons focused on the cavity with a total power density of up to 10W/cm3 and microwaving the mould to form a foamed product. The mould is characterized by having any or one of a susceptor or microwavable interactive material applied to an internal surface of the mould; a microwave interactive material impregnated into the mould material; a mould material that acts as a microwave interactive material to enable the internal surface of the mould to heat uniformly.
Patent NZ-516625-A (NZ)
Title: Ironing board with steam recovery system
Inventor: CARLO ROSA
IPC: D06F81/08
Filed: 2002-01-15
Abstract: An ironing board has an iron 6 connected with a steam boiler 3 and an ironing plank 2 having a perforated upper surface 201 and a lower tank 202 for gathering the condensation water from the steam. The ironing board also has a reservoir 7 for recovering the condensation water in the tank 202 and a pump system for re-circulating the water from the recovery reservoir back to the steam boiler.
Patent NZ-517497-A (NZ)
Title: The synergistic effect of tyrosine kinase inhibitors and chemical castration agents in the treatment of prostate cancer
Inventor: DIONNE CRAIG A
IPC: A61K38/04
Filed: 1998-08-13
Abstract: Described is a composition comprising a synergistic combination of a tyrosine kinase inhibitor and a chemical castration agent. The tyrosine kinase inhibitor is selected from a trkA inhibitor, a trkB inhibitor, a trkC inhibitor, or an indolocarbazole. The chemical castration agents include oestrogens; LHRH agonists, e.g., leuprolide acetate (LUPRON®) and goserelin acetate (ZOLADEX®); LHRH antagonists, e.g., ANTIDE® (Ares-Serono) and GANIRELIX® (Akzo Nobel); and antiandrogens, e.g., flutamide and nilutamide. The use of aforementioned tyrosine kinase inhibitors and chemical castration agents in the preparation of a medicament for inhibiting prostrate tumour progression in a mammal is also described. (62) Divided out of 502646
Patent NZ-520691-A (NZ)
Title: Novel galenical form for oral administration with prolonged release of molsidomine
Inventor: GECZY JOZSEF-MICHEL
IPC: A61K9/22
Filed: 2001-02-22
Abstract: Sustained release galenical form of molsidomine for oral administration for treating angina attack in its various forms (exertion angina, spastic angina, mixed angina) is disclosed, wherein the galenical form contains a therapeutically efficient amount of molsidomine or one of its active metabolites and it has a dissolution rate in vitro [measured by spectrophotometry at 286 or 311 nm according to the European Pharmacopeia, 3rd edition (or U.S.P XXIV) at 50 rpm in 500 ml of a 0.1N HCl medium, at 37 °C] of: 15 to 25 % of molsidomine released after 1 hour, 20 to 35 % of molsidomine released after 2 hours, 50 to 65 % of molsidomine released after 6 hours, 75 to 95 % of molsidomine released after 12 hours, > 85 % of molsidomine released after 18 hours, > 90 % of molsidomine released after 24 hours, wherein the plasma peak of molsidomine obtained in vivo occurring between 2.5 to 5 hours, preferably between 3 to 4 hours, following the administration of galenical form and exhibiting a value between 25 and 40 ng/ml of plasma.
Patent NZ-523045-A (NZ)
Title: An accessory for a snowboard comprising a plate arranged to be secured releasably to the snowboard
Inventor: RAWCLIFFE NICK
IPC: A63C10/02
Filed: 2001-06-28
Abstract: An accessory for a snowboard comprises a plate (12) adapted to support the feet of a rider, the plate being constructed and arranged to be secured releasably to the snowboard, and having steering means (22, 24) which are pivotably mounted on the plate and which are constructed to extend away form the snowboard in a first arrangement, and to lie substantially parallel to the snowboard in a further arrangement. The steering means include an elongated member which, in the first arrangement, is lockable at a chosen angle to the base of the snowboard in use.
Patent NZ-524224-A (NZ)
Title: Manipulation of plant senescence using an myb gene promoter and cytokinin biosynthesis genes
Inventor: SPANGENBERG GERMAN
IPC: A01H5/00
Filed: 2001-08-30
Abstract: Methods of manipulating senescence in plants are disclosed. Also described are vectors useful in such methods, transformed plants with modified senescence characteristics and plant cells, seeds and other parts of such plants.
Patent NZ-528369-A (NZ)
Title: Dual solid chemical feed system
Inventor: ROSSI ANTHONY M
IPC: C02F1/00
Filed: 2002-03-19
Abstract: A solid chemical feed system, preferably including two feed bowls, comprises a quantity of solid chemicals that dissolve upon immersion in water to form a liquid solution. A sump is provided to receive liquid solution from the feed bowls, the liquid solution with additive chemicals being used as a treatment for cooling towers, boilers, or other industrial processes to inhibit corrosion and rust. The feed system comprises a valve system that is controlled by a sensor that detects the conductivity of the liquid solution to alternatingly switch the introduction of liquid solution from one feed bowl to the other feed bowl. As such, upon depletion of chemical feed in one bowl, desired treatment will continue and the empty bowl may be replaced without disruption of liquid solution supply
Patent NZ-536163-A (NZ)
Title: Method of producing a cleansing tablet
Inventor: GOWTY ANDREW
Filed: 2004-10-26
Abstract: Disclosed is a method for producing a cleansing tablet, the method comprising: (a) forming at least one tablet layer, (b) applying at least one active or beneficial ingredient to the layer, and (c) providing a damper and adding a gel material to the active or beneficial ingredient in a manner such that the gel material impacts the damper, to at least partially absorb the kinetic energy of the gel material, immediately prior to contacting the active or beneficial ingredient.
Patent NZ-536520-A (NZ)
Title: Carbon fiber reinforced plastic bipolar plates with continuous electrical pathways
Inventor: LECOSTAOUEC JEAN-FRANCOIS
IPC: H01M50/534
Filed: 2003-04-25
Abstract: An electrically conductive article for use as an electrode in a fuel cell or battery is disclosed. The electrically conductive article includes carbonized or graphitized reinforcement fibers that are electrically conductive and filler fibers contained in a matrix. The matrix has a thickness and surface features such that the carbonized or graphitized reinforcement fibers are mechanically oriented by needling the fibers so that they are parallel to the thickness. This increases through thickness conductivity of the article, wherein the carbonized or graphitized reinforcement fibers and filler fibers include a porous structure impregnated with a thermoplastic polymer to create the matrix.
Patent NZ-536579-A (NZ)
Title: Pentafluorosulfanyl-benzoylguanidine, method for the production thereof and its utilization as medicament or diagnostic agent and medicament containing same
Inventor: KLEEMANN HEINZ-WERNER
Filed: 2003-05-05
Abstract: Pentafluorosulfanyl-benzoylguanidines of formula (I) and (II) are disclosed, wherein R1 to R4 are as defined in the specification. These pentafluorosulfanyl-benzoylguanidines are suitable as antiarrhythmic medicaments with cardioprotective components for the prophylaxis or treatment of infarction and for the treatment of angina pectoris. They also preventively inhibit pathophysiological processes during the occurrence of ischaemically induced injuries, more particularly the triggering of ischaemically induced cardiac arrhythmia.
Patent NZ-536972-A (NZ)
Title: Benzoic acid derivatives as modulators of ppar alpha and gamma
Inventor: LI LANNA
IPC: C07D213/40
Filed: 2003-06-17
Abstract: Disclosed are compounds of formula I, wherein: R1 is optionally substituted aryl or heterocyclic group, V is O, S, NR8 or a bond, W is O, S, N(R9)C(O), NR10 or a bond, R2 is halo, optionally substituted alkyl or alkoxy, acyl, aryl, aryl-alkyl, CN or NO2, R3 is halo, optionally substituted alkyl or alkoxy, acyl, aryl, aryl-alkyl or CN, and the remaining substituents are defined herein. The compounds are use for the manufacture of medicaments for the treatment of insulin resistance.
Patent NZ-537816-A (NZ)
Title: An autologous T cell vaccine for the treatment of multiple sclerosis
Inventor: ZHANG JINGWU Z
IPC: C12Q1/68
Filed: 2003-08-06
Abstract: An autologous T cell vaccine comprising attenuated T cells that are reactive against at least six epitopes, wherein the epitopes comprise SEQ ID NOs:1-6. Also disclosed is a method of making the vaccine for the treatment of multiple sclerosis.