baber/WOPTO huggingface dataset:
Patent JP-2001508739-A (JP)
Title: 積層及び入れ子容器
IPC: B65D21/04
Filed: 1998-01-20
Abstract: (57)【要約】
２つの容器が第１の相対方向にある場合に類似容器をネスチングさせるための構成を有する容器１１０が提供される。各容器は、相対的に１８０°旋回させた場合に積層することができる。積層手段１１２を容器の底部分に収納させることが可能であり、あるいは、これを引き起こすことで中間高さでの積層を可能とすることができる。積層手段１１２とフック１５２とを一体形成し、容器が、該容器を下方の容器内にネスチングさせる場合に上方の容器のフック１５２がネスチング動作により釈放されそれにより、積層手段１１２が下方の収納位置にヒンジ廻動するように形成される。
Patent JP-H11505197-A (JP)
Title: 車軸を取り囲むことにより圧迫するトレーリングアームサスペンション
IPC: B60G9/04
Filed: 1995-05-16
Abstract: (57)【要約】
２本のアーム（１８）がフレームの両側に固定され、車輪を支持する車軸（１２）がアーム間に懸架されている車両フレーム（１０）に、地面と接する車輪を取り付けるための車両サスペンション機構。車軸を部分的に取り囲むラッパープレート（３４）、ラッパーの内側表面に取り付けたアダプタープレート（３９）、およびラッパーを車軸の周りに、およびアダプタープレートを車軸に対して圧迫するための少なくとも１本のボルト（３８）により、車軸はアームに固定される。この配置により、ラッパープレートは車軸を支持し、強化する。ラッパープレートは、それが取り囲む車軸部分の輪郭に全体的に一致している。車軸は断面が正方形、長円形、六角形、八角形、長方形またはＤ字形でよい。ラッパープレートおよびアダプタープレートは、車軸に対して実質的に横切る方向の力を加える。ラッパーには、その側部の、車軸の隣接する側部の垂直方向で中間点に相当する位置に、開口部（４２）が設けてある。車軸に対するラッパープレートの横方向移動を阻止するために、円形の座金（４４）が車軸の両側に、ラッパープレートの側部にある開口部と正確に重なる様に溶接してある。
Patent JP-H11508391-A (JP)
Title: 間欠的に駆動しうる磁気テープに情報信号をセグメント毎に記録する装置
IPC: G11B15/48
Filed: 1997-04-02
Abstract: (57)【要約】
記録モードがアクティブのときにテープ駆動装置（５３）により間欠的に駆動される磁気テープ（３）上の記録トラック（２）に少なくとも１つの回転駆動磁気ヘッド（４、５）により情報信号をセグメント毎に記録する装置（１）においては、静止磁気テープ（３）を最後に走査した傾斜記録トラック（２ n ）と部分的にオーバラップする傾斜再生トラック（７５）に沿って走査し、最後に走査した傾斜記録トラック（２ n ）に記録された情報信号セグメント（フィールド信号）を再生することができる。この装置（１）に、テープの長さ方向において傾斜再生トラック’７５）が該傾斜再生トラックにより部分的にオーバラップされる最後に走査した傾斜記録トラック（２ n ）に対し占める瞬時相対位置を決定し、決定した相対位置を表す位置情報（ＬＩ）を発生する第１手段（７６）を設けるとともに、この位置情報（ＬＩ）を供給され、次の記録サイクル中に、この位置情報（ＬＩ）に応じてテープ駆動装置（５３）を制御する第２手段（１２０）を設ける。
Patent JP-2001525087-A (JP)
Title: 計数可能な電子貨幣システムおよび方法
IPC: G07F7/08
Filed: 1998-03-30
Abstract: (57)【要約】
連番を付けた（５１−Ｌ）電子コイン（５１−Ｄ）および電子小切手（５１−０，５２−０，５３−０）の形態で記憶された貨幣価値を用い、各トランザクション毎の完全な中央での会計を必要とせずに、効率的にセキュリティの監視を行うスマート・カード支払システム（５１，５２，５３）。システム・レベルのセキュリティの中心的監視は、出所まで遡る電子コイン（５１−Ｄ）のトランザクション経路の効率的な追跡と結合した統計的サンプリング技法を含む。少量のデータ記憶および伝送（５１−Ｅ，５２−２，５２−１１）のみを利用し、大型の集中トランザクション記録データベースの必要性を排除する。消費者のプライバシー保護、およびカード間貨幣転送を行う柔軟性が、これによって強化され、しかもシステム全体のセキュリティの検証、ならびにセキュリティ侵害の迅速な検出および追跡を可能とする。電子コイン（５１−Ｄ）に多数の版を設けることにより、システムの透明で周期的な更新、およびセキュリティ基本線の再確立を可能とし、更に消費者が紛失または放棄した記憶貨幣価値の規則的な再生にも対処する。
Patent JP-2002512556-A (JP)
Title: 高活性触媒の調製方法ならびに該触媒およびその使用
IPC: B01J23/889
Filed: 1998-04-17
Abstract: (57)【要約】
一酸化炭素の水素化反応を行うのに有用な触媒、特にフィッシャー・トロプシュ触媒の調製方法と、このような反応、特にフィッシャー・トロプシュ反応を行うための該触媒の使用と、該プロセスにより製造される組成物。触媒の調製時、約3〜6個の合計炭素原子、好ましくは約4〜5個の合計炭素原子を有する多官能性カルボン酸の溶液を用いて、レニウムの化合物もしくは塩と、１種もしくは複数種の触媒金属、例えば銅もしくは鉄族金属、具体的には鉄、コバルト、もしくはニッケルの化合物または塩とを、チタニアなどの耐火性無機酸化物担体上に含浸および分散させる。わずか少量存在させることが必要なレニウムの働きで、酸により分散された１種もしくは複数種の触媒金属を十分かつ完全に還元することができる。この場合、調製時に１種もしくは複数種の触媒金属の分散および還元の両方を効果的に行うためにより高濃度のレニウムが必要であった従来の調製物の場合よりも、より少ないレニウム充填量でより高い触媒活性が得られる。驚くべきことに、酸を用いて分散させた場合には、還元を促進するために必要となるレニウムの量は約1/10程度に低下する。
Patent JP-2002508899-A (JP)
Title: 無線リンクパラメータに基づく移動体通信ネットワークにおける音声品質測定
IPC: H04W24/00
Filed: 1998-05-15
Abstract: (57)【要約】
利用できる無線リンクパラメータを用いて、移動体セルラー電話通信ネットワークにおいて、音声品質の測定を行なう方法及びシステムがここに開示されている。好適な実施の形態においては、本方法は、BER、FER、RxLev、ハンドオーバー統計値、ソフト情報、及び音声エネルギーといった、標準の、或いはそうでなくとも利用可能な、無線リンクパラメータを受取るステップを含む。時間情報は、無線リンクパラメータから獲得され、時間パラメータを生成する。時間パラメータを統計的に分析することにより、例えば、タイムインターバルの間の最大値、最小値、平均値、標準偏差、及び自己相関関数を導き出すことが出来る。その時間パラメータは、更に音声品質に近い関係を持つ相関パラメータを求めるために組み合わされる。評価手段は、音声品質の評価値を算出するために相関パラメータを用いる。本発明の方法は、送信されたパラメータから時間情報と相関関係を利用するものである。更に、その方法は、従来の方法に比して本質的に単純で信頼できる。また更に、この技術によれば、オペレータは、ネットワークの至る所で音質状態の測定を行なうことができる。
Patent JP-2002510419-A (JP)
Title: ストリーミング・プロトコルにおけるギャップ・カバレッジのための方法および装置
IPC: H04N21/442
Filed: 1999-03-05
Abstract: (57)【要約】
データ・ストリーミング・プロトコルにギャップ・カバレッジを提供するデータ・ストリーミング・クライアント（２０）は、プロセッサ（２２）と、データ・ストリーミング・クライアントによって要求された要求データを格納するメモリ（２４）と、ギャップ・データを格納するメモリ（２８）とによって構成される。プロセッサは、好ましくは、要求データ（１２）および適切なギャップ・データ（１４）を含むストリーミング・データをサーバ（１６）から受信する（７６）ようにプログラミングされる。また、プロセッサは、要求データを適切なギャップ・データから区別でき(７８)、要求データを第１バッファ（２４）に格納し、適切なギャップ・データを第２バッファ（２８）に格納できる。
Patent MX-153680-A (MX)
Inventor: SEBRING ROBERT E
IPC: B65H81/00
Filed: 1980-05-19
Abstract: A method of making coreless hollow filament bundles comprises winding a hollow filament 20 around a drum 22 having a number of axially extending vanes 24. The winding is formed in layers, each layer being a helix and adjacent layers being wound in opposite directions axially of the drum so that all the turns of the helix forming one layer cross all the turns of the helices forming the adjacent layers. The winding is then slid along the drum so that it is axially collapsed and forms an annular rope around one end of the drum. The annular rope is then cut into segments, each segment being the length of rope between adjacent vanes 24. Each segment forms a filament bundle and the ends of the filament lengths in each bundle are potted in the usual way.
Patent MX-152342-A (MX)
Inventor: MENGES JOHN RUDOLPH
IPC: A61B17/128
Filed: 1983-02-04
Abstract: A multiple clip applier including a handle and a cartridge which holds a large number of ligating clips and which snaps into a cartridge-receiving channel on the handle. The handle operates like an elongated scissors with scissors handles at one end and jaws at the other to which clips may be delivered in rapid succession. Opening and closing the scissors handles operates the mechanism of the handle to open and close the jaws and to provide a long stroke motion for delivering clips from the end of the cartridge to the nose section. Clips may be indexed through the cartridge by reciprocating parts of the cartridge with respect to one another with a short stroke cocking motion captured from the long stroke delivery motion from a cooperating slot and pin mechanism. These two motions are accomplished within the envelope of motion of the normal opening and closing of the scissors handles to operate the jaws of the applier and to feed and index clips from the cartridge to the nose. The mechanism of the present invention permits the overall shape of the handle to be small, compact and readily adaptable for use even deep in an incision site.
Patent MX-157457-A (MX)
Inventor: RZEWINSKY LEONARD
IPC: B24C7/00
Filed: 1983-12-08
Abstract: An improved apparatus for dispensing cleaning powder in an air stream to be directed onto the surface of teeth includes a fluid-tight chamber for containing a supply of cleaning powder and having an open space above the powder, with an elongated tube mounted in the chamber and having a bottom end adjacent the bottom of the chamber and an open top end above the powder supply in the chamber, and with openings in the tube permitting limited flow of powder into the tube by gravity. Air under pressure is directed into the bottom of the tube to entrain the powder and discharge it in an air-powder stream from the open top of the tube. An outlet in the sidewall of the chamber permits air and powder to flow out under pressure, and a movable deflection member deflects the stream of air and entrained powder from the open top of the tube above the powder supply and generally toward the outlet.
Patent NZ-203021-A (NZ)
Title: Substituted-s-triazolo(3,4-a)phthalazine derivatives and pharmaceutical compositions
Inventor: OCCELLI E
IPC: C07D237/34
Filed: 1983-01-13
Abstract: The present invention refers to new s-triazolo[3,4-a]phthalazine derivatives, to the process for their preparation and to the pharmaceutical compositions containing them.
Patent NZ-207477-A (NZ)
Title: Impregnated molecular sieves,their use and preparation
Inventor: SUTT R F
IPC: B01J20/32
Filed: 1984-03-12
Abstract: The instant invention is directed to a molecular sieve comprising a carbonaceous substrate impregnated with an organic polymer having a molecular weight of at least 400, as determined by vapor phase osmometry, or with an inorganic polymer at a dosage of at least 0.001 weight percent (based on the substrate weight) up to a maximum dosage which still allows the resulting sieve to separate gas or liquid mixtures containing components of at least two different molecular diameters, molecular weights or molecular shapes.The instant invention is also directed to a process for preparing a molecular sieve which comprises impregnating a carbonaceous substrate with an inorganic polymer having a molecular weight of at least 400, as determined by vapor phase osmometry, or with an inorganic polymer at a dosage of at least 0.001 weight percent (based on the substrate weight) up to a maximum dosage which still allows the resulting sieve to separate gas or liquid mixtures containing components of at least two different molecular diameters, molecular weights or molecular shapes.The instant invention is also directed to a process for separating gas or liquid mixtures containing components of at least two different molecular diameters, molecular weights or molecular shapes, comprising passing the liquid or gas through a molecular sieve comprising a carbonaceous substrate impregnated with an organic polymer having a molecular weight of at least 400, as determined by vapor phase osmometry, or with an inorganic polymer at a dosage of at least 0.001 weight percent (based on the substrate weight) up to a maximum dosage which still allows the resulting sieve to separate gas or liquid mixtures containing components of at least two different molecular diameters, molecular weights or molecular shapes.
Patent NZ-216156-A (NZ)
Title: Lightweight cooling tower formed from fibreglass reinforced resin
Inventor: BARDO C J
IPC: E04H5/12
Filed: 1986-05-14
Abstract: A cooling tower is formed from fiberglass reinforced polyester resin structural components including a basin, vertically extending columns, vertical side panels, and a cover. The fill material for heat/mass exchange is supported directly by the basin to eliminate the weight of a separate support system and to reduce the load on the columns and panels. A fan is mounted on the cover, and the weight of the fan is supported by the cover and the columns. The panels do not have to support the weight of the cover and the fan, and the panels can be formed of relatively thin, lightweight material. The columns do not have to support the weight of the fill material and can also be relatively lightweight.
Patent NZ-222185-A (NZ)
Title: N-substituted methanesulphonamide derivatives, and anticancer compositions containing such
Inventor: MASATOSHI YAMATO
IPC: C07D495/04
Filed: 1987-10-15
Abstract: The present invention provides a quinoline base compound represented by the following general formula (1) of: <CHEM> wherein X is CH2, O or S. Further provided are the process for the preparation of the aforementioned quinoline base compound and an anticancer agent including the same as a pharmacologically efficacious component.
Patent NZ-231034-A (NZ)
Title: Controlling insects using an aqueous dispersion of pyrogenic silica
Inventor: VRBA CENEK H
IPC: A01N59/00
Filed: 1989-10-17
Abstract: Insects are combatted by treating the insects with a pyrogenically produced and hydrophobic silica. The insects can be sprayed with an aqueous dispersion of the pyrogenically produced and hydrophobic silica. Alternatively, the insects can be dusted with the silica in powdery form.
Patent NZ-232762-A (NZ)
Title: 1-(substituted phenyl)-3-cyano-4-alkane-sulphenyl, -sulphinyl, and -sulphonyl pyrazole derivatives; preparatory processes; pesticidal and veterinary compositions
Inventor: D SILVA THEMISTOCLES D J
IPC: A61K31/415
Filed: 1990-03-02
Abstract: The invention describes novel 3-cyano-4-sulfenylated-5-alkoxy-1-arylpyrazoles of general formula(I)   <CHEM>  wherein typically preferred substituents are:  R is C1 to C4 alkyl fully substituted by halogen; R1 is C1 to C4 alkyl, C3 to C6 alkenyl and alkynyl or aralkyl (each of which may be optionally substituted), dialkylaminocarbonyl or a group -P(=X)(Oalkyl)(Salkyl) wherein X is oxygen or sulfur;  R2, R3, R5 and R6 are each hydrogen or halogen;  R4 is CF3, OCF3, SCF3, SOCF3, SO2CF3, OCHF2, halogen or alkyl; and  n is 0, 1 or 2. The invention further relates to intermediates and processes to make the compounds as well as to compositions thereof and to methods of control of arthopod (especially insect) nematode, helminth, and protozoan pests.
Patent NZ-242447-A (NZ)
Title: Bradykinin receptor antagonist and pharmaceutical compositions thereof
Inventor: KYLE DONALD JAMES
IPC: A61P17/02
Filed: 1992-04-22
Abstract: The substitution of the L-Pro at the 7-position with D-Phe or D-Tic and substitution of the L-Phe at the 8-position with hydroxyproline ethers and thioethers of the peptide hormone bradykinin and other additional substituted analogs of bradykinin converts bradykinin agonists into bradykinin antagonists. The invention further includes additional modifications at other positions within the novel 7- and 8-position modified bradykinin antagonists, which increase enzyme resistance, antagonist potency, and/or specificity of the new bradykinin antagonists. The analogs produced are useful in treating conditions and diseases of a mammal and human in which an excess of bradykinin or related kinins are produced or injected as by insect bites.
Patent NZ-246205-A (NZ)
Title: Cycloalkyl piperazinylalkylcarbamate esters and pharmaceutical compositions
Inventor: CLIFFE IAN ANTHONY
IPC: A61P25/22
Filed: 1992-12-24
Abstract: PCT No. PCT/GB92/02399 Sec. 371 Date Jul. 7, 1994 Sec. 102(e) Date Jul. 7, 1994 PCT Filed Dec. 24, 1992 PCT Pub. No. WO93/14076 PCT Pub. Date Jul. 22, 1993.    <IMAGE>  (I)  This invention concerns compounds of formula (I) where A is an alkylene chain of 2 to 5 carbon atoms optionally substituted by one or more lower alkyl groups, R represents hydrogen or one or two same or different lower alkyl groups, R1 is a monocyclic aryl or heteroaryl radical, R2 is a mono or bicyclic aryl radical and R3 is cycloalkyl. The compounds of the invention are useful as antidepressant, antianxiety, or hypotensive agents; or for regulating the sleep/wake cycle, feeding behavior and/or sexual function; and for treating cognition disorders.
Patent NZ-255003-A (NZ)
Title: Power amplifier feedback: compensating for phase rotation
Inventor: BERGSTEN PAR
IPC: H03F1/32
Filed: 1993-08-02
Abstract: An apparatus for compensating the phase rotation in the feedback loop of a cartesian feedback power amplifier in a final transmitter stage for quadrature modulation of the complex difference signal between a complex input signal and the corresponding complex feedback signal with a complex modulation signal for forming a modulated real valued first signal and for quadrature modulation of the output signal from the power amplifier with a complex demodulation signal for forming the complex feedback signal. The phase shift between the first signal and the second signal and between the quadrature component of the first signal and the second signal is detected for determining the phase rotation of the feedback loop. Furthermore, the phase rotation of the complex modulation signal can be changed with a compensating phase rotation defined by the determined phase rotation.
Patent NZ-261524-A (NZ)
Title: Road marking: grooved thermoplastic stripe applied to road, reflective material applied to stripe after application
Inventor: MARCATO FORREST C
IPC: E01C23/22
Filed: 1994-01-14
Abstract: A method and apparatus for applying a traffic stripe (10) having improved reflectivity includes a vehicle having an apparatus (50) for applying the traffic stripe, an applying assembly (52) for dispensing a reflective material over the traffic stripe, another applying apparatus (66) for applying an anti-adhesion agent, and a deformation apparatus (64) disposed rearward thereof for forming interval grooves in the traffic stripe. The application of the anti-adhesion agent directly onto the traffic stripe or onto the deformation apparatus prevents the freshly applied traffics tripe from lifting off the road surface and adhering to the deformation apparatus. <IMAGE>
Patent NZ-272069-A (NZ)
Title: Sound waves applied to casting pool of metal strip casting apparatus for increased cooling rate and refined surface structure of casting metal
Inventor: FREEMAN JOHN
IPC: B22D27/08
Filed: 1995-05-04
Abstract: A method and an apparatus of continuously casting metal strip (20) is disclosed. A casting pool (30) of molten metal is formed in contact with a moving casting surface such that metal solidifies from the pool (30) onto the moving casting surface. In addition, sound waves are applied to the casting pool of molten metal to induce relative vibratory movement between the molten metal of the casting pool (30) and the casting surface.
Patent NZ-286132-A (NZ)
Title: Concentric double sleeve for rotary printing cylinder
Inventor: ROSSINI FELICE
IPC: B41F27/10
Filed: 1996-03-06
Abstract: A sleeve (3) for a rotary rotogravure or flexography printing cylinder (1), said cylinder (1) comprising a generally steel mandrel (2) to be rotated about its axis (K) when used in a printing machine, said sleeve (3) being able to be mounted on said mandrel (2). The sleeve (3) comprises two cylindrical portions (5, 6) removably associated with each other and forming, during the rotation of the mandrel (2), substantially a single body in the sense of being torsionally locked together. <IMAGE>
Patent NZ-307716-A (NZ)
Title: 4-[3,5-bis(trifluoromethyl)phenyl]-2-(3,4-dichlorophenyl)-1-[[( substituted heterocyclic)amino]acetyl] piperazine derivatives and medicaments
Inventor: SHUE HO-JANE
IPC: C07D409/14
Filed: 1996-05-01
Abstract: The invention relates to compounds of formula (I). These compounds are neurokinin antagonists. These compounds are useful in the treatment of chronic airway diseases such as asthma.
Patent NZ-309203-A (NZ)
Title: Thermally insulating building material
Inventor: STEPANENKO ALEXANDR VIKTOROVIC
IPC: C04B20/06
Filed: 1996-04-12
Abstract: The disclosure relates to a thermally insulating building material based on alkalized and hydrated siliceous raw material and obtained by crushing solids and thoroughly mixing the raw ingredients, steaming the raw material mixture and thermally expanding the semi-finished blocks thus obtained. The material is intended for use as bulk thermal blanketing and as filling material for light concrete (in dispersed form) and as building elements, buildings and structures (in the form of slabs and blocks). In order to regulate the dimensions of the finished products over a wide range and stabilize mechanical strength and water absorption, the material is obtained by cooling the steamed raw material mixture until it becomes brittle and the brittle material is crushed before being expanded to form the semi-finished blocks.
Patent NZ-332453-A (NZ)
Title: (1R,5S,6S)-6-[(1R)-1-hydroxyethyl]-1-methyl-2-[(2S,4S)-2-[(3R)-3-methylaminomethylpyrrolidin-1-ylcarbonyl]pyrrolidin-4-ylthio]-1-carbapen-2-em-3-carboxylic acid for the prevention or treatment of bacterial infections
Inventor: KAWAMOTO ISAO
IPC: A61P31/04
Filed: 1997-04-25
Abstract: A composition comprising (1R,5S,6S)-6-[(1R)-1-hydroxyethyl]-1-methyl-2-[(2S,4S)-2-[(3R)-3-methylaminomethylpyrrolidin-1-ylcarbonyl]pyrrolidin-4-ylthio]-1-carbapen-2-em-3-carboxylic acid for the prevention or treatment of bacterial infections.
Patent NZ-332759-A (NZ)
Title: Coolant pump for IC engine, pump attached to radiator header tank
Inventor: SAYERS JONATHON ALAN
IPC: F16H49/00
Filed: 1998-11-11
Abstract: A coolant pump 26 for an IC engine has flange 28 which is bolted to a corresponding flange 30 on the radiator header tank.  The coolant pump is driven by electric motor 12.  The  drive shaft of the coolant pump may be at right angles to the longitudinal axis of header tank 10.  The pump may incorporate two impellers, one of them being a in bypass passage, allowing coolant to bypass the radiator when the engine is warming up.
Patent NZ-332910-A (NZ)
Title: Coiled insect fumigant in spiral form with enlarged outer portion for initial increased combustion rate
Inventor: RUNKEL JAMES J
IPC: A01M13/00
Filed: 1997-05-13
Abstract: Disclosed herein are mosquito coils having an enlarged outer portion (11) for providing quick initial coverage of an insect control ingredient. The coil is typically provided with urea for greater breakage resistance and kerosene and peanut shell powder to improve igniting and burning characteristics.
Patent NZ-500590-A (NZ)
Title: Carbocyclic and heterocyclic substituted semicarbazones and thiosemicarbazones and the use thereof
Inventor: WANG YAN
IPC: A61K31/44
Filed: 1998-04-22
Abstract: The compound of formula (I) wherein: Y is oxygen or sulfur. R1 is hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, haloalkyl, aryl, aminoalkyl, hydroxyalkyl, alkoxyalkyl or carboxyalkyl. R21, R22 and R23 are independently hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, haloalkyl, aryl, aminoalkyl, hydroxyalkyl, alkoxyalkyl or carboxyalkyl; or R21 is defined as above, and R22 and R23 together with the nitrogen atom to which they are attached, form a piperadine, piperazine or morpholine. A1 and A2 are independently aryl, heteroaryl, saturated or partially unsaturated carbocycle or saturated or partially unsaturated heterocycle, any of which is optionally substituted. X is one of O, S, NR24, CR25R26, C(O), NR24C(O), C(O)NR24, SO, SO2 or a covalent bond; where R24 is alkyl, cycloalkyl, alkenyl, alkynyl, haloalkyl, aryl, aminoalkyl, hydroxyalkyl, alkoxyalkyl or carboxyalkyl and R25 and R26 are independently hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, haloalkyl, aryl, aminoalkyl, hydroxyalkyl, alkoxyalkyl or carboxyalkyl. The compound may be used in medicaments for treating, preventing or ameliorating neuronal damage following global and focal ischemia; neurodegenerative conditions such as amyiotrophic lateral sclerosis (ALS); otoneurotoxicity and eye diseases involving glutamate toxicity; pain; diabetic neuropathy and urinary incontinence.  The compound may also be used in medicaments for use as anticonvulsants, antimanic depressants, local anesthetics and antiarrhythmics.
Patent NZ-501619-A (NZ)
Title: Tricyclic sulfonamide inhibitors of farnesyl-protein transferase
Inventor: NJOROGE F GEORGE
IPC: A61K31/496
Filed: 1998-06-15
Abstract: The following compounds are inhibitors of farnesyl protein transferase, and may be used in a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. (+)-4-(3-Bromo-8, 10-dichloro-6,11-dihydro-5H- benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(methylsulfonyl) piperidine (+)-4-(3-Bromo-8, 10-dichloro-6,11-dihydro-5H- benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-N,N-dimethyl-1-piperidinesulfonamide (+)-4-(3-Bromo-8, 10-dichloro-6,11-dihydro-5H- benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(aminosulfonyl) piperidine (+)-4-(3,10-Dibromo-8-chloro-11-dihydro-5H- benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(methylsulfonyl) piperidine (+)-4-(3,10-Dibromo-8-chloro-11-dihydro-5H- benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(ethylsulfonyl) piperidine (+)-4-(3,10-Dibromo-8-chloro-1 1-dihydro-5H- benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1 -(propylsulfonyl) piperidine (+)-4-(3,10-Dibromo-8-chloro-11-dihydro-5H- benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(isopropylsulfonyl) piperidine (+)-4-(3,10-Dibromo-8-chloro-11 -dihydro-5H-benzo[5,6]cyclohepta[1,2- b]pyridin-11-yl)-1 -(butylsulfonyl) piperidine (+)-4-(3,10-Dibromo-8-chloro-11-dihydro-5H-benzo[5,6]cyclohepta[1,2- b]pyridin-11-yl)-1-(trifluoromethyl sulfonyl) piperidine (+)-4-(3,10-Dibromo-8-chloro-11-dihydro-5H- benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(trifluoroethyl sulfonyl) piperidine (+)-4-(3,10-Dibromo-8-chloro-11-dihydro-5H- benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(vinylsulfonyl) piperidine (+)-4-(3,10-Dibromo-8-chloro-6, 11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11 (R)-yl)-1-(phenylsulfonyl) piperidine (+)-4-(3,10-Dibromo-8-chloro-6,11-dihydro-5H- benzo[5,6]cyclohepta[1,2-b]pyridin-11 (R)-yl)-1-[(1-methyl-1H-imidazol-4yl)sulfonyl] piperidine; and (+)-4-(3, 10-Dibromo-8-chloro-6, 11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11 (R)-yl)-1-[(5-(3-isoxazolyl)-2-thienylsulfonyl] piperidine