baber/WOPTO huggingface dataset:
Patent CA-2471096-A1 (CA)
Title: Formulation and dosage form for increasing oral bioavailability of hydrophilic macromolecules
Inventor: YUM SI-HONG
IPC: A61K9/127
Filed: 2002-12-18
Abstract: The present invention includes a formulation and dosage form for enhancing t he bioavailability of orally administered hydrophilic macromolecules. The formulation of the present invention includes a permeation enhancer, a hydrophilic macromolecule, and a carrier that exhibits in-situ gelling properties, such as nonionic surfactant. The formulation of the present invention is delivered within the GI tract as a liquid having at least some affinity for the surface of the GI mucosal membrane. Once released, it is believed that the liquid formulation spreads across one or more areas of the surface of the GI mucosal membrane, where the carrier of the formulation the n transitions into a biodhesive gel in-situ. As a bioadhesive gel, the formulation of the present invention present the hydrophilic macromolecule a nd the permeation enhancer at the surface of the GI mucosal membrane at concentrations sufficient to increase absorption of the hydrophilic macromolecule through the GI mucosal membrane over a period of time. The dosage form of the present invention incorporates the formulation of the present invention and may be designed to provide the controlled release of t he formulation within the GI tract over a desired period of time.
Patent CA-2471645-A1 (CA)
Inventor: MUYLDERMANS SERGE
IPC: A61K47/48
Filed: 2002-12-23
Abstract: L'invention concerne de nouveaux immunoconjugués exempts de chaînes légères et comprenant au moins un domaine variable d'un anticorps à chaîne lourde. Ces immunoconjugués peuvent servir dans la préparation d'un médicament destiné au traitement de tumeurs.
Patent CA-2472529-A1 (CA)
Inventor: DU PLESSIS FRANCOIS EBERHARDT
IPC: G01N21/31
Filed: 2003-01-22
Abstract: A method of spectral analysis of a mineral (M) in granular form is disclosed.  The mineral (M) is moved through an illumination zone (18) and a beam of light is directed at the mineral (M) to illuminate it. Light reflected off the mineral (M) is collected and then spectrally analysed to obtain information pertaining to the composition of the granular material (M). The mineral (M) is in the form of a layer having an undersurface (20) and a top surface (22). The illumination zone (18) is intermediate the undersurface (20) and the top surface (22).
Patent CA-2472631-A1 (CA)
Title: Trim hardware carrier
Inventor: FRITSCH MANFRED
IPC: B60J5/04
Filed: 2003-01-07
Abstract: A method for assembling a motor vehicle door includes the steps of affixing a plurality of hardware components to a secondary trim component to form a door module assembly. The door module assembly is attached to the structural door body. A trim panel is secured to the structural door body overlaying the door module assembly. The secondary trim component has a map pocket wall and the trim panel has a map pocket opening. When the trim panel overlays the secondary trim component, the trim panel cooperates with the secondary trim component to define a map pocket.
Patent CA-2473655-A1 (CA)
Inventor: KLEIN JAMES
IPC: G06Q10/02
Filed: 2003-01-21
Abstract: Système et procédé prévoyant un réseau centralisé pour faciliter les réservations et/ou les services associés aux voyages, voir figure 1. Le système comprend un réseau (110) comportant des sites concentrateurs fournissant une connexion centralisée pour systèmes de distribution mondiale/systèmes de réservation informatique (120), agents de voyage (150), et terminaux de point de service (130) d'agences de voyage. Le système comprend des terminaux de point de service multifonctions qui fournissent une pluralité de modules pour diverses applications relatives aux voyages tels qu'un module intégré de réservation par courriel, un module d'intégration de téléphonie informatique, une super base de données d'enregistrement de noms de passagers, une base de données de clients, un module de planification de voyages, un module de gestion de relations clients, un module flux de travaux et un module de recherche de tarifs réduits.
Patent CA-2474060-A1 (CA)
Title: Slot die
Inventor: PRUGH DAVID NEVILLE
IPC: B29C48/08
Filed: 2003-02-05
Abstract: This invention relates to a slot die for forming a coating. More particularl y, this invention relates to a die comprising a first plate (46) having a first lip (47), a first location (48), and a second location (49) where the first location (48) is between the second location (49) and the first lip (47); a second plate (51) having a second lip (52), a third location (53), and a fourth location (54) where the third location (53) is between the fourth location (54) and the second lip (52) the second location (49) of the first plate (46) being a distance away from the fourth location (54) of the second plate (51); and a shim (56) having a top seat (57) and a bottom seat (58); t he top seat (57) of the shim (56) contacting the first plate (46) at the first location (48) and the bottom seat (58) of the shim (56) contacting the secon d plate (51) at the third location (53), so as to form a slot (61) in the die (45) which terminates at an orifice (62) and is bounded at the orifice by th e first (47) and second lips (52), the first (47) and second lips (52) having a gap there between, the gap having a size (G1); a means for adjustably connecting the first plate (46) to the second plate (51) at the second location (49) and the fourth location (54) such that the size of the gap (G1 ) between the first (47) and second lips (52) is adjustable by adjusting the distance between the second location (49) of the first plate (46) and the fourth location (54) of the second plate (51).
Patent CA-2476500-A1 (CA)
Title: Methods and systems for exchanging and/or transferring various forms of value
Inventor: DORAN MICHAEL
IPC: G07D7/00
Filed: 2003-02-14
Abstract: Methods and systems for exchanging various forms of value, including coins, currency, credit, debit, and/or bank account funds, for prepaid cash cards, credit cards, phone cards, and the like. In one embodiment, a value exchange machine includes a coin input region (106), a coin sorting/counting apparatus (112), a card reader, and a communications facility configured to communicate (113) with a remote computer network. In another embodiment, a value exchange system includes one or more of the value exchange machines connected to one or more remote computers via a communications link. A user wishing to purchase, for example, a prepaid cash card can visit one of the value exchange machines, select the desired transaction (115), and pay for the card with coins, currency, a credit card, a debit card, and/or bank account funds. After confirming payment, the value exchange machine dispenses the card to the user.
Patent CA-2481629-A1 (CA)
Inventor: BRENNAN ROBERT L
IPC: H04R3/00
Filed: 2004-09-15
Abstract: A method and system for active noise cancellation is provided. The system employs subband processing, and preferably implements over-sampled filterbank. The system is applicable to adaptive noise cancellation, adaptive echo cancellation for portable listening devices, such as headsets and other similar listening devices.
Patent CA-2481699-A1 (CA)
Title: Steering arrangement for a ship propelled by water jet
Inventor: KARLSSON SVEN-GUNNAR
IPC: B63H11/11
Filed: 2003-04-30
Abstract: The present invention relates to a steering arrangement for ships propelled by water jet, comprising a steering device (6) that is pivotal about an essentially vertical shaft (5) having a first centre line (C1), at least one hydraulic cylinder (2; 3) for turning said steering device (6), which hydraulic cylinder is directly or indirectly articulately connected to the ship~s body at one of its ends (2B; 3B), a turning device (4) connected to said shaft (5), for attachment to a second end (2A; 3A) of said hydraulic cylinder at a distance from said shaft (5), a reversing device (7) arranged in connection with said steering device (6) about an essentially horizontal sha ft (12), an additional hydraulic cylinder (9) arranged to act on the reversing device (7), the additional hydraulic cylinder (9) following the movement of the steering device (6), characterised in that all the hydraulic cylinders (2,3,9) are arranged within a sheltered space (1) located above the extensio n of said vertical shaft (5), which space (1) is accessible for maintenance fr om the inside of the ship, and in that the arranging of said hydraulic cylinder (9) at the turning device (4) in relation to the steering device (6) is arranged such that the relative position of the reversing device (7) is uninfluenced by the relativeposition of the steering device (6).
Patent CA-2483044-A1 (CA)
Title: Roaming method between wireless local area network and cellular network
Inventor: SHIN YONG-SIK
IPC: H04W76/02
Filed: 2002-11-29
Abstract: The present invention relates to a roaming method between a WLAN and a cellular network which can interwork the WLAN and the cellular network on th e basis of a mobile IP system for smooth roaming. In data communication in the WLAN and/or the cellular network using the mobile IP system, the roaming method between the WLAN and the cellular network includes a step wherein a packet data serving node of the cellular network which recognizes allocation of an IP address to a specific mobile terminal notifies information on a current access state of the mobile terminal to an access point managing mean s of the WLAN located in a current service area of the mobile terminal, a step wherein the access point managing means which the mobile terminal newly accesses requests address renewal to replace an address of the packet data serving node by its address, allocates an IP address to the mobile terminal according to the renewal result, and notifies it to the packet data serving node, and a step wherein the packet data serving node which receives the notification message from the access point managing means transmits data obtained during the roaming due to the movement to the access point managing node, whereby the roaming is performed from the cellular network to the WLAN . In the same manner, the roamingcan be performed from the WLAN to the cellula r network.
Patent CA-2486762-A1 (CA)
Title: Electrodes de batterie a revetement en carbone
Inventor: KELLEY KURTIS C
IPC: H01M4/73
Filed: 2003-05-15
Abstract: L'invention concerne un procédé de réalisation d'électrode résistant à la corrosion (14), pour batterie (1), qui consiste à établir une grille électrode destinée à être utilisée dans une batterie, et à exposer l'électrode à un environnement renfermant du carbone vaporisé. Il est possible de transférer au moins une partie du carbone de cet environnement à l'électrode.
Patent CA-2487818-A1 (CA)
Title: Tubulure et dispositifs d'aspiration a adaptation de flux
Inventor: BARRETT GRAHAM DAVID
IPC: A61F9/007
Filed: 2003-06-06
Abstract: L'invention concerne une tubulure d'aspiration destinée à être utilisée dans un système de pharmacoémulsification présentant une lumière modifiée améliorant la résistance d'écoulement de fluide à travers la lumière pour réduire un afflux de post-occlusion, la modification comprenant des évidements ou des parties saillantes formés dans la surface intérieure de la lumière, un objet se déplaçant librement disposé dans le chemin d'écoulement de la lumière, ou une ou plusieurs courbes.
Patent CA-2492148-A1 (CA)
Title: Process for producing aromatic dicarboxylic acids under supercritical conditions
Inventor: POLIAKOFF MARTYN
IPC: C07B61/00
Filed: 2003-07-02
Abstract: A process for the simultaneous or sequential production in the same reaction zone of two or more dicarboxylic acids selected from orthophthalic acid, isophthalic acid and terephthalic acid comprising contacting simultaneously or sequentially in the presence of a catalyst, one or more precursors of each o f at least two dicarboxylic acids selected from orthophthalic acid, terephthal ic acid and isophthalic acid with an oxidant, such contact being effected with said precursors and the oxidant in an aqueous solvent comprising water under supercritical conditions or near supercritical conditions close to the supercritical point is disclosed. In preferred embodiments, the process is f or the simultaneous or sequential production in the same reaction zone of orthophthalic acid, terephthalic acid and isophthalic acid.
Patent CA-2492238-A1 (CA)
Title: Method for identifying cellular growth inhibitors
Inventor: HAMELIN MICHEL J
IPC: C12Q1/68
Filed: 2003-07-14
Abstract: The present invention is a method which permits the selective screening for growth-inhibiting substances having a known mechanism of action; i.e., substances which inhibit or otherwise interfere with an enzyme or other gene product whose function is required for the growth or survival of the cell. The method employs cells (e.g., bacterial cells) that contain a nucleic acid fragment that encodes an RNA fragment that can interfere with the expression of a gene product (e.g., an anti-sense RNA that hybridizes to a mRNA), wherein expression of the RNA fragment pre-sensitizes the cell to substances (drugs) that act at the gene product (e.g., a protein or RNA). The cells lose the capability to express the RNA fragment. In the method, the recombinant cells are grown in a nutrient medium in the presence of a test substance under conditions in which expression of the RNA fragment occurs at a level that pre-sensitizes the cell to substances that act at the targeted gene product. The growth conditions are also controlled such that the cells lose the capability to express the RNA fragment. When the test substance is a growth inhibitor that acts on the targeted gene product, the cells lacking the RNA fragment (revertant cells) will have a growth advantage over cells containing the RNA  fragment, and the growth of revertant cells will occur. The method of the invention includes monitoring the cell growth for the appearance of revertant cells, which leads to the identification of selective growth inhibitors having a specific mode of action.
Patent CA-2495930-A1 (CA)
Title: Adjustable chair
Inventor: ADAMS JOSEPH W
IPC: A47C3/24
Filed: 2005-02-03
Abstract: An adjustable leg for a chair includes a leg housing, secured to a seat, that includes a threaded inner wall. A leg extension is received into the leg housing and includes external threaded portions that mate with the threaded inner wall. A tab in the leg housing cooperates with the external threaded portions and secures the leg extension at a predefined position in the leg housing.
Patent CA-2496737-A1 (CA)
Title: Gas lift mandrel
Inventor: ROTH BRIAN A
IPC: E21B23/03
Filed: 2003-07-31
Abstract: A side-pocket gas lift mandrel having tapered end caps threaded onto the ends of the mandrel with metal-to-metal sealing threads. The thickness of each made up thread set is the same as the thickness of the small end of each end cap, resulting in a mandrel having the same outside diameter as if the end caps were welded on, without sacrificing any inside diameter in the small ends of the end caps, compared to a welded mandrel.
Patent CA-2498766-A1 (CA)
Title: Improved pumping apparatus and process for slurry polymerization in loop reactors
Inventor: ZELLERS DALE A
IPC: C08F2/00
Filed: 2003-09-16
Abstract: An olefin polymerization process and apparatus wherein a fluid slurry comprising monomer, diluent and catalyst is circulated in a continuous loop reactor by two or more pumps (100, 102). The process and apparatus allow operating the reaction at significantly higher solids content in the circulating fluid slurry. In a preferred embodiment, the fluid slurry is circulated by two impellers (22a, 22b) arranged so that the downstream impeller (22a) benefits from the rotational energy imparted by the upstream impeller (22b). An olefin polymerization process operating at higher reactor solids by virtue of more aggressive circulation has improved efficiencies, particularly in larger-volume reactors.
Patent CA-2502390-A1 (CA)
Title: Pixel engine data caching mechanism
Inventor: POOLE GLENN C
IPC: G06F12/02
Filed: 1997-03-04
Abstract: A pipeline processor in a graphics computer system is provided with a data caching mechanism which supplies requested data to one of the stages in the pipeline processor after a request from a prior stage in the pipeline processor. With the sequential nature of the pipeline processor, a prior stage which knows in advance the data which will be requested by a subsequent stage can make a memory request to the disclosed data caching mechanism. When processing reaches the subsequent stage in the pipeline processor, the displayed data caching mechanism provides the requested data to the subsequent processing stage with minimal or no lag time from memory access. In addition, the disclosed data caching mechanism features an adaptive cache memory which is optimized to provide maximum performance based on the particular mode in which the associated pipeline processor is operating.
Patent CA-2503239-A1 (CA)
Inventor: KRAJCI EDWARD J
IPC: H01H19/00
Filed: 2005-03-22
Abstract: An architectural preset rotary and preset slide control device comprising an N-mode latch mechanically coupled to a switch having a pole and a plurality of receiving terminals. The device further comprises a variable control component that is electrically coupled to the switch such that when the latch is activated into one of the N modes, the switch pole is caused to be electrically coupled to one of the receiving terminals allowing electrical energy at the pole to be routed through the switch to one of the receiving terminals. The variable control component controls the amount of electrical energy that is routed through the switch. The device has a modular design in that the switch, latch, variable control component and other parts of the device are single piece parts that facilitate the assembly of the device during its manufacture.
Patent CA-2506189-A1 (CA)
Title: Carbon black compositions and their applications
Inventor: VAN LIERDE ANDRE
IPC: C09C1/56
Filed: 2003-11-17
Abstract: A carbon black composition of carbon black coated with nickel, iron, cobalt or yttrium, blends of such metal doped carbon black with thermoplastic or rubber as well as applications of the metal coated carbon black are disclosed. The material has ferromagnetic properties and allows applications in materials influenced by magnetic and/or electric, and/or electromagnetic fields. The other application is for use in carbon black reactors as a catalyst or nucleus for new production of na~ nostructures of carbon black, in particular carbon nanotubes.
Patent CA-2506978-A1 (CA)
Inventor: KAPOUN ANN M
IPC: A61K31/137
Filed: 2003-11-20
Abstract: L'invention concerne des méthodes permettant de moduler la voie .szlig.-adrénergique, et en particulier des méthodes qui permettent de contrer un changement pathologique, par exemple une perte de la sensibilité .szlig.-adrénergique, dans la voie de transduction du signal .szlig.-adrénergique, par l'administration d'une dose efficace d'un composé capable d'inhiber la signalisation TGF-.szlig. via un récepteur de TGF-.szlig..
Patent CA-2509402-A1 (CA)
Title: Couche barriere pour ecrans electroluminescents dielectriques a film epais
Inventor: YE YUFENG
IPC: H05B33/10
Filed: 2003-12-01
Abstract: L'invention concerne une nouvelle sous-structure d'un écran électroluminescent diélectrique à film épais et un écran électroluminescent diélectrique à film épais présentant ladite sous-structure. La sous-structure comporte une couche barrière entre un substrat et une couche diélectrique de film épais. La couche barrière est chimiquement inerte par rapport au substrat et la couche diélectrique de film épais et la couche barrière inhibent la diffusion d'au moins une espèce chimique. La sous-structure fait preuve d'une capacitance plus élevée pour la couche diélectrique épaisse assurant ainsi une luminance de l'écran plus importante et une tendance réduite à une interruption diélectrique de la couche diélectrique épaisse. La couche barrière permet l'utilisation de substrats à moindres coûts, notamment le verre.
Patent CA-2509600-A1 (CA)
Inventor: THORPE ANDREW JOHN
IPC: A61K31/4245
Filed: 2003-12-03
Abstract: La présente invention concerne une méthode de traitement des troubles du système nerveux central et d'autres troubles, ladite méthode consistant à administrer un ligand alpha2delta tel que, par exemple, un composé représenté par la formule (I) ou un sel pharmaceutiquement acceptable de ce dernier. Dans la formule (I), R¿1? représente hydrogène ou alkyle inférieur linéaire ou ramifié et n représente un entier compris entre 4 et 6. Formule (I)
Patent CA-2509796-A1 (CA)
Title: Process for modifying drug crystal formation
Inventor: WIECKHUSEN DIERK
IPC: A61K9/14
Filed: 2004-01-19
Abstract: A process for modifying the crystal habit of acicular drug substances, crystals obtained by such a process, and particular crystal forms or modifications of mycophenolic acid or mycophenolate sodium are provided, as well as pharmaceutical compositions comprising the crystals, methods of treatment and uses thereof.
Patent CA-2511022-A1 (CA)
Title: Sodium percarbonate particles with improved storage stability
Inventor: JAKOB HARALD
IPC: C01B15/10
Filed: 2003-12-18
Abstract: The invention relates to sodium percarbonate particles with improved storage stability in the presence of builders. The inventive sodium percarbonate particles contain, on the surface thereof, between 0.01 and 1 wt. % of a hydrophobic, fine-particle oxide of the elements silicon, aluminium, or titanium or a mixed oxide of said elements. The inventive particles can be produced by mixing sodium percarbonate particles with between 0.01 and 1 wt. % of the hydrophobic, fine-particle oxide, the sodium percarbonate being preferably mixed, in the dry state, with the fine-particle oxide. The inventive particles have a high storage stability, can be handled and stored without dust formation and without caking of the particles, and can be easil y dispersed in water without leaving any residues.
Patent CA-2512427-A1 (CA)
Inventor: HEAD PHILIP
IPC: H02G3/32
Filed: 2004-01-12
Abstract: A cable clamp device for use in a well bore to secure cables to pipes and the like, includes a relatively flexible fastening member, and a retaining means that accepts and retains the fastening member. The cable clamp device including a cable restraining means capable of accepting and constraining at least one cable as the cable clamp device is attached to a pipe. This can include flexible resilient parts that deform to accept the cable and thereafter hold it in position, particularly a number of flexible tabs extending approximately perpendicularly to the direction the cable is to run, and capable of flexing deforming toward the direction the cable is to run to accept and hold the cable.
Patent CA-2514085-A1 (CA)
Title: Method and apparatus for cooling system failure detection
Inventor: NALLAPA VENKATAPATHI R
IPC: H02K11/00
Filed: 2005-07-29
Abstract: A system and method for detecting failure of a cooling system in an alternating current machine, such as a motor and/or a generator. For example , in one embodiment energy wasting is initiated and a failure is indicated if a temperature rises by more than a selected amount over a selected time period.