baber/WOPTO huggingface dataset:
Patent CZ-302911-B6 (CZ)
Title: Device for a body's spherical motion control
Inventor: VALASEK MICHAEL
IPC: B23Q1/32
Filed: 2007-10-31
Abstract: In the present invention, there is disclosed a device for controlling spherical motion of a body (1) connected with a frame (5) by means of a spherical joint (2) arranged on a shank (9, 10) connecting the body (1) with the frame (5) and further connected through the mediation of actuating arms (3) with drives (4, 6, 7, 8, 11) wherein the shank (9, 10) is divided into a stationary and mobile parts and the spherical joint (2) is arranged between the stationary part (9) of the shank, which is firmly fixed to the frame (5) and the second part (10) of the shank, which is firmly fixed to the moved body (1). The number of parallel arms (3) with drives (4, 6, 7, 8, 11) is redundant, i.e. higher than the number of freedom of the body (1Q) relative to the frame (5) that is in the given case three-rotation about three axes. In order to increase the accuracy of both the self-calibration itself and a follow-up positioning of the body (1) in the work area (for instance in a work area of a machine tool or manipulator tilting head for which the device is used) and to achieve a large range of the body's (1) turning, the number of parallel arms (3) with drives (4, 6, 7, 8, 11) is preferably at least five and the length of the stationary part of the shank (9) connected to the frame (5) is longer than the distance of the body (1) edge from the point of connection of the shank mobile part (10) to the body (1).
Patent CZ-303198-B6 (CZ)
Title: Silage microcontainer and method of filling thereof
Inventor: SKLADANKA JIRI
IPC: A23N17/00
Filed: 2010-07-08
Abstract: In the present invention, there is disclosed an elongate silage microcontainer provided in its bottom section with an internal flange (3) above which a perforated bottom (4) is disposed. From below, the microcontainer is closed by a lower rubber sleeve (7a) wherein the upper section of the cylindrical vessel (2) is provided with a lid (5) for arranging on the top of a filling. A weight (6) is located on the cylindrical vessel (2) lid (5). An upper rubber sleeve (7b) is inserted on the cylindrical vessel (2) upper end. There is also disclosed a method of filling the above-described silage microcontainer, wherein the filling method is characterized in that the silage microcontainer (1) with the lower rubber sleeve (7a) is put into a bed (22) in a frame (27) lower section while in the frame (27) upper section the silage microcontainer (1) is gripper in a clamping mechanism (24) and secured by a closure, wherein the silage microcontainer (1) is first filled by hand through an upper opening (23) with biomass (8). Subsequently, a compressor (16) is activated and a pressing end piece (14) compresses the material down. This process is then repeated several times until complete filling, whereupon a lid (5) with a weight (6) is freely put onto a compacted biomass (8) and the upper end is sealed by the upper rubber sleeve (7b).
Patent CZ-304417-B6 (CZ)
Title: Film of electrooxidized nostotrebin 6 with permselective properties for low-molecular biologically active substances, electrochemical sensor and method of determining these substances
Inventor: VACEK JAN
IPC: C07C49/747
Filed: 2012-03-30
Abstract: In the present invention, there is disclosed an electrooxidized nostotrebin 6 film prepared by electrosynthesis of a compact film of nostotrebin 6, 2,2´-bis[4,5-bis(4-hydroxybenzyl)-2-(4-hydroxyphenyl)-cyclopent-4-ene-1,3-dione], on carbon electrodes (glassy carbon, carbon fiber), gold electrodes, platinum electrodes and similar solid electrodes. The electrosynthesis is based on polarization of an electrode by constant or cyclically changing potential of 600 to 1000 mV (.ny.s. Ag/AgCl) within a supporting electrolyte (pH 7 to 14), which contains nostotrebin 6. The thus obtained permselective films can be used in the production of electrochemical sensors and can thereby ensure their selectivity.
Patent SK-286697-B6 (SK)
Title: Micropropagation of big-fruits variety of cornel tree (Cornus mas "Macrocarpa")
Inventor: DURKOVIC JAROSLAV
IPC: A01H4/00
Filed: 2006-08-31
Abstract: Micro-propagation of big-fruits variety of cornel tree (Cornus mas "Macrocarpa") under conditions in vitro, based on the modification of cultivation medium WPM with regard to determination of pH range and concentrations of calcium compounds for long-time cultivation with formation of  multi-peak cultures and adventitious rhisogenesis in vitro, all under the exactly defined cultivation conditions.
Patent SK-286309-B6 (SK)
Title: Method for electrochemical production of Ni(0) phosphite and diphosphite complexes and method of olefin hydrocyanation or alkene nitrite isomerization
Inventor: STEPANOV ANDREI ALEKSANDROVICH
IPC: C25B3/13
Filed: 2000-08-17
Abstract: Method for electrochemical production of phosphite or diphosphite Ni(0) complexes comprising: (a) dissolving metallic nickel from an anode in an aprotic solvent in a diaphragmless electrolyzer containing the anode and cathode to produce Ni2+ nickel ions, and (b) electroreduction of Ni2+ ions on the cathode in the presence of one or more phosphorus ligands by direct or alternating current, to thereby produce the complex. Phosphite or diphosphite Ni(0) complexes may also be obtained by a modified method comprising: the step (a), (b) reducing the nickel ions in solution in the presence of one or more phosphorus ligands by using a metal that is more electropositive than nickel, thereby producing oxidized nickel, and (c) electroreducing and depositing said oxidized nickel at the cathode, thereby producing the complexes. Disclosed method of olefin hydrocyanation or alkene nitrite isomerization comprises producing phosphite or diphosphite Ni(0) complexes according to the steps (a) and (b), and after that olefin hydrocyanation or alkene nitrite isomerization using said complexes as a catalyst.
Patent SK-285873-B6 (SK)
Title: Method of producing a package
Inventor: GANZ PETER
IPC: B65D75/00
Filed: 2000-05-15
Abstract: Method for the production of a package made from a flexible material which tears well in all directions, such as plastic film, paper, aluminium foil or a similar material, that can be opened in a controlled manner, with a finish to quide a tears initiated in the material in a controlled manner. Material that is in the form of a strip as is liquid and then cures is applied to the packaging material. Flexible material is provided with a contoured coating, such as lacquers, inks, adhesives, hotmelt, coldseal adhesives, either alone or in combination, along the outer edge of which the tear initiated in the material is quided, where the contoured coating is applied to the flexible material by a printing and transfer process and in particular by the transfer printing process and where a plastic film is biaxially oriented and has a coating lacquer in particular applied to a limited area of it.
Patent CZ-300758-B6 (CZ)
Title: Powder-like composition containing perforated microstructures
Inventor: TARARA THOMAS E
IPC: A61K9/22
Filed: 1998-09-29
Abstract: In the present invention, there is disclosed a process for preparing microparticles suitable for application of a biologically active agent into respiratory system of a patient. These microparticles can be used as such or in the form of dry powders or combined with a non-aqueous suspension medium to provide stabilized dispersions. In preferred embodiments, the disclosed particles will be used in conjunction with inhalation devices such as metered dose inhalers, dry powder inhalers, atomizers or nebulizers for targeted delivery of the agent to mucosal surfaces.
Patent CZ-301191-B6 (CZ)
Title: Process for producing 17beta-(N-t-butyl carbamoyl)-4-aza-5alpha-androst-1-en-3-one in polymorphic Form II
Inventor: DOLLING ULF H
IPC: C07J9/00
Filed: 1993-11-05
Abstract: The present invention relates to a process for producing polymorphic Form II of 17{beta}-(N-tert-butyl carbamoyl)-4-aza-5{alpha}-androst-1-3-one in substantially pure form, comprising the steps of: (1) crystallization from a solution of finasteride in a water immiscible organic solvent and 0% or more by weight of water, producing solvated and non-solvated finasteride in solution, such that the amount of organic solvent and water in the solution is sufficient to cause the solubility of the non-solvated form of finasteride to be exceeded and the non-solvated form of finasteride to be less soluble than any other form of finasteride in the organic solvent and water solution; (2) recovering the resultant solid phase; and (3) removing the solvent therefrom.
Patent CZ-300551-B6 (CZ)
Title: Pregelatinized starch in controlled release formulation
Inventor: VANDECRUYS ROGER PETRUS GEREBERN
IPC: A61K9/22
Filed: 2000-03-24
Abstract: The present invention relates to the use of pregelatinized starch to prevent instant dumping of essentially whole dose from a hydrophilic controlled release formulation. The invention also relates to a hydrophilic controlled release formulation, more in particular a hydrophilic controlled release matrix formulation, and solid dosage forms prepared from this formulation, preferably for once daily oral administration. The hydrophilic controlled release formulation comprises pregelatinized starch, one or more active ingredients, one or more viscous hydrophilic polymers and optionally pharmaceutically acceptable formulating agents. Preferred hydrophilic polymers include hydroxypropyl cellulose and hydroxypropyl methylcellulose.
Patent CZ-297735-B6 (CZ)
Title: Transport device that can be pushed by hands
Inventor: HOMMERLE JUERGEN
IPC: B62B5/08
Filed: 2001-10-10
Abstract: The present invention relates to a transporting device (1), which can be moved by hand and which is provided with a loading space (4) for loading articles, with a chassis (2) having rollers (3), and with an electric motor driven drive wheel (5). Said drive wheel is also arranged on the chassis (2), can be controlled by a control device (6), and serves to drive the transporting device (1). The transporting device (1) has a ladder (12), which can swivel upwards, which is supported on the ground when extended, and which is lifted from the ground when stowed. A pushing device (7) is provided that has a measuring instrument (8), which is connected to the control device (6) and which is capable of measuring a force exerted by the hand onto the pushing device (7) in order to effect a control of the drive wheel (5) via the control device (6). The invention is characterized in that the ladder (12) is connected to a switching device (9), which is integrated inside the existing electric circuit (11) and which serves to prevent the drive wheel (5) from being driven when the ladder (12) is in its extended position and, vice versa, enables the drive wheel (5) to be driven when the ladder (12) is in its stowed position.
Patent SK-286430-B6 (SK)
Title: Lock bar mounting for a window or door
Inventor: OESTERMANN MARKUS
IPC: E05C9/00
Filed: 2000-05-18
Abstract: The lock bars (2, 3, 4) are configured in such a way that they can be externally mounted on pre-manufactured casements or leaves (1). The guide means of the lock bars (2, 3, 4) engage with the edge strips (10) of a groove (11) pertaining to said casements or leaves and are introduced into said groove (11) via the longitudinal opening thereof. Said guide means are elastically displaced or turned inwards and stopped in an assembly position in which engagement occurs with the respective edge strip (10).
Patent SK-287994-B6 (SK)
Title: Benzopyran derivatives and pharmaceutical composition containing them
Inventor: OHRAI KAZUHIKO
IPC: C07D498/04
Filed: 2005-03-23
Abstract: It is described a benzopyran derivatives of the formula (I) or (II), or pharmaceutically acceptable salts thereof wherein R1 and R2 are methyl group, R3 is hydroxy group, R4 is hydrogen atom, R5 is hydrogen atom, the (CH2)m-V-(CH2)n moiety is -CH2-CH2-, R6 is C6-14aryl group or C2-9heteroaryl group, which may be arbitrarily substituted with 1 to 3 R10; C2-4alkyl group; C3-8cycloalkyl group; C3-8cycloalkenyl group which may be arbitrarily substituted with halogen atom, carboxy group or hydroxyl group, R10 is a halogen atom, a hydroxy group or an amino group and the ring structure A is chose from nitrogen heterocycles; pharmaceutical composition comprising said derivative and its use for treating arrhythmia.
Patent BR-PI9909678-B8 (BR)
Inventor: ALFONS BOSMAN
IPC: A61K38/00
Filed: 1999-04-15
Abstract: The present invention relates to a method for purifying a cysteine containing recombinantly expressed protein comprising at least 2, preferably 3 or 4 and even more preferably all of the following steps:  (a) sulphonation of a lysate from recombinant host cells or lysis of recombinant host cells in the presence of guanidinium chloride followed by a subsequent sulphonation of the cell lysate, (b) treatment with a zwitterionic detergent, preferably after removal of the cell debris, (c) purification of the sulphonated version of the recombinant protein or purification of the sulphonated version of the recombinant protein with subsequent removal of the zwitterionic detergent, with said purification being preferably chromatography, more preferably a Ni-IMAC chromatography with said recombinant protein being a His-tagged recombinant protein, (d) desulphonation of the sulphonated version of the recombinant protein, preferably with a molar excess of DTT, (e) storage in the presence of a molar excess of DTT.
Patent EP-1645006-B8 (EP)
Inventor: LAURENT JEAN-YVES
IPC: H01M4/86
Filed: 2004-06-18
Granted: 2007-08-29
Abstract: A fuel cell comprises a substrate supporting an electrolytic membrane (4) having first and second surfaces carrying first and second electrodes. The electrodes respectively include first and second catalytic elements and circulation systems for feeding first and second fluids in the proximity of the catalytic elements. The circulation systems are conceived in a manner to make the first fluid circulate essentially parallel to the first surface of the electrolytic membrane in a cavity formed in the substrate. An independent claim is also included for the fabrication of this fuel cell.
Patent EP-1786660-B8 (EP)
Inventor: HAMPE RENE
IPC: B62D25/08
Filed: 2005-09-06
Granted: 2008-03-19
Abstract: The invention relates to a suspension strut top mounting (1) in a body structure of a motor vehicle. The suspension strut top mounting (1) consists of two half-shells (2, 3) which are connected together in a rigid manner on the outer edge thereof (4, 5) and form a cavity (4) therebetween and are placed on top of each other in the support region (7) of the suspension strut top mounting (8). The suspension strut top mounting (1) is integrated into the body structure as a connecting node for adjacent hollow profiles (10, 12) of the body structure such that it reinforces and delivers a positive contribution to the crash behavior of the vehicle structure.
Patent EP-1841792-B8 (EP)
Inventor: SINN HANNSJOERG
IPC: A61K31/04
Filed: 2006-01-20
Granted: 2010-05-12
Abstract: The present invention is directed to a Gyrase inhibitor-protein conjugate; in particular a Gyrase inhibitor-albumin conjugate. The present invention further provides methods of the treatment of inflammatory conditions and tumors. Methods of making and producing a Gyrase inhibitor-protein conjugate are also disclosed.
Patent BR-PI0520449-B8 (BR)
Title: artigo absorvente tendo características de mascaramento de mancha
Inventor: WILLIAM G F KELLY
IPC: A61F13/512
Filed: 2005-07-19
Abstract: artigo absorvente tendo características de mascaramento de mancha. a presente invenção refere-se a um absorvente higiênico que inclui uma camada de cobertura que faceia o corpo e um sistema absorvente adjacente à camada de cobertura para receber líquido dali, sendo que o absorvente tem propriedades aprimoradas de tratamento e mascaramento de fluidos.
Patent BR-PI0611409-B8 (BR)
Title: preparação oral compreendendo lurasidona
Inventor: KAZUYUKI FUJIHARA
IPC: A61K47/38
Filed: 2006-05-26
Abstract: preparação oral e método de granulação de uma mistura em pó. a presente invenção refere-se a uma preparação para administração oral incluindo: um amido pré-gelatinizado contendo cloridrato de n-[4-[4-(1 ,2-benzisotiazol-3-il)-1-piperazinil]-(2r,3r)-2,3-tetrametieno-butil]-(1 'r,2's,3'r,4's)-2,3-biciclo[2,2,1]heptanodicarboxiimida (lurasidona) representado pela fórmula (1) como ingrediente ativo; um excipiente solúvel em água; e um ligante polimérico solúvel em água, a preparação apresentando um nível invariante de comportamento em eluição mesmo quando o teor de seu ingrediente ativo é variado.
Patent BR-PI1006915-B8 (BR)
Title: composição compreendendo extrato lipofílico de zingiber officinale e extrato de cynara scolymus, e seu uso
Inventor: EZIO BOMBARDELLI
IPC: A61K36/28
Filed: 2010-01-15
Abstract: composições compreendendo um extrato lipofílico de zingiber officinale e um extrato de cynara scolymus que são úteis para a prevenção e tratamento de refluxo esofágico e da síndrome do cólon irritável. a presente invenção refere-se a composições consistindo em uma combinação de extrato de zingiber offcinales e um extrato de cynara scolymus, que são úteis para a aprevenção e tratamento do refluxo esofágico e da síndrome do cólon irritável, para a redução da sonolência pós-prandial e tendo atividades procinéticas e antidispépticas.
Patent BR-PI9702918-B8 (BR)
Title: processo de produção, obtenção, purificação do antitumoral 3-[1,2-dihidro-5-(5-hidroxi-1h-indol-3-1l)-2-oxo-3h-pirrol-3-ilideno] -1,3-dihidro-2h-indol-2-ona
Inventor: NELSON EDUARDO DURÁN CABALLERO
IPC: C12N5/077
Filed: 1997-09-25
Abstract: <b>"processo de produção, obtenção, purificação do antitumoral 3-[1,2-dihidro-5-(5-hidroxi-1h-indol-3-il)-2-oxo-3h-pirrol-3-ilideno]-1,3-dihidro-2h-indol-2-ona"<d>. a presente invenção se refere a uma metodologia para biosíntese de violaceína utilizando arroz como forte de carbono em ágar nutriente. a purificação foi realizada adicionando acetona para extração do pigmento. logo o extrato acetônico lava-se com acetato de etila saturada com cloreto de sódio. a solução acetônica contendo o pigemento foi secada em mgso~ 4~ seco e a seguir filtrada novamente. o filtrado acetônico seco foi evaporado a vácuo, obtendo 1500 mg de extrato bruto de violaceína. posteriormente, foi realizada obtendo 1500 mg de extrato bruto de violaceína. posteriormente, foi realizada a pre-purificação em um extrator tipo soxhlet utilizando seqüencialmente clorofórmico, éter etílico e acetona. concentrou-se a acetona e logo foi precipitada com éter etílico, centrifugou-se a 5000 rpm durante 10 minutos, descartando o sobrenadante, obtendo-se assim a violaceína parcialmente purificada. a purificação final foi realizada por hplc em metanol/água. após um teste com 52 linhagens de células em cultura, violaceina apresentou alta eficiência como antitumoral contra células cancerosas de pulmão, colon, ovário, próstata e linfomas-associados ao aids.
Patent BR-PI9900296-B8 (BR)
Title: método de diagnóstico para detecção de mycobacterium tuberculosis
Inventor: ARNALDO ZAHA
IPC: G01N33/50
Filed: 1999-01-15
Abstract: <mu>"método de diagnóstico para detecção de mycobacterium tuberculosis"<mv>trata-se de um método para detecção de mycobacterium tuberculosis utilizando a reação em cadeia da polimerase caracterizada, pela pesquisa de dna de bacilo de m. tuberculosis causador da tuberculose, utilizando um reagente extrator. este método auxiliar o diagnóstico da tuberculose pela detecção de dna do bacilo mycobacterium tuberculosis, causador da doença e presente nos fluidos biológicos do doente. este dna é purificado utilizando-se um reagente extrator e após, amplificado pela técnica de reação em cadeia da polimerase (pcr) com oligonucleotídeos complementares a região is 6110 presente no genoma deste microrganismo. a detecção dos produtos amplificados é feita em gel de agarose 2% e hibridização em membrana de náilon.
Patent AU-2005317903-B8 (AU)
Title: Radiolabelled conjugates of RGD-containing peptides and methods for their preparation via click-chemistry
Inventor: GLASER MATTHIAS
IPC: A61K51/08
Filed: 2005-12-09
Granted: 2012-01-19
Abstract: The invention relates to radiodiagnostic and radiotherapeutic agents, including biologically active vectors labelled with radionuclides. It further relates to methods and reagents labelling a vector such as a peptide comprising reaction of a compound of formula (I) with a compound of formula (II): R*-L2 -N (II) or, a compound of formula (III) with a compound of formula (IV) in the presence of a Cu (I) catalyst. The resultant labelled conjugates are useful as diagnostic agents, for example, as radiopharmaceuticals more specifically for use in Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) or for radiotherapy.
Patent AU-2006200717-B8 (AU)
Title: Isoindole-imide compounds, compositions, and uses thereof
Inventor: MAN HON-WAH
IPC: A61K31/495
Filed: 2006-02-21
Granted: 2009-04-30
Abstract: The invention relates to isoindole-imide compounds and pharmaceutically acceptable salts, hydrates, solvates, clathrates, enantiomers, diastereomers, racemates, or mixtures of stereoisomers thereof, pharmaceutical compositions comprising these isoindole-imide compounds, and methods for reducing the level of cytokines and their precursors in mammals. In particular, the invention pertains to isoindole-imide compounds that are potent inhibitors of the production of the TNF-± in mammals. The isoindole-imides described herein are useful for treating or preventing diseases or disorders in mammals, for example, cancers, such as solid tumors and blood-born tumors; heart disease, such as congestive heart failure; osteoporosis; and genetic, inflammatory, allergic, and autoimmune diseases.
Patent EP-1486287-B9 (EP)
Inventor: POSER DANILO
IPC: A47B13/08
Filed: 2004-06-08
Granted: 2008-12-03
Abstract: A method for obtaining metallic hollow sandwich panels providing one or more profiled elements that are axially elongated and are externally provided, at a first wing (2) and at an opposite second wing (3), with first seats (5, 6) for the flush positioning of a first metal plate (8) and of a second metal plate (9) and second seats (10a, 10b) for means (11) for fixing the first and second metal plates to the one or more profiled elements. The ends of the one or more profiled elements are then cut and arranged so that they are mutually adjacent, in order to obtain an annular ridge (17) that is closed perimetrically for flush containment of the first and second metal plates at the first seats. It is then possible to apply the fixing means at the second seats of the first and second surfaces and then couple the first and second metal plates to the fixing means so as to obtain a preset metallic hollow sandwich panel.
Patent EP-1586216-B9 (EP)
Inventor: BLOMQVIST MIKKO
IPC: H04W4/021
Filed: 2004-01-19
Granted: 2012-03-14
Abstract: A method for activating a location-based function, at least one item of position data is determined for the function as a condition for activating the function. A device in a wireless communication network examines at least one property of the network to decide whether positioning of the device ( 1 ) is conducted. Likewise, a system may provide a location-based function, for which at least one item of position data is determined as a condition for activating the function. A program in which the method is applied is also provided.