baber/WOPTO huggingface dataset:
Patent DE-69011024-T2 (DE)
Inventor: PLAQUEVENT JEAN-CHRISTOPHE
IPC: C07C327/28
Filed: 1990-09-14
Granted: 1994-11-10
Abstract: Amino acid drivatives, enkephalinase and ACE inhibitors, of the formula (Ia) and (Ib), wherein R1 represents a biphenyl group or one of the groups (a), wherein Z, Y and n have the meanings (b) or (c), wherein R'1, represents a hydrogen atom, a lower alkyl group; a phenyl group; a lower phenylalkylene group. R2 represents a hydrogen atom; a lower alkyl group; a lower hydroxyalkylene group; a lower phenylalkylene group; a lower hydroxyphenylalkylene group; a lower aminoalkylene group; a lower guanidinoalkylene group; a lower mercaptoalkylene group; a lower thioalkylene lower alkyl group; a lower imidazolylkylene group; a lower indolylalkylene group; a lower carbamylalkylene group; a lower carboxyalkylene group or one of the groupings (d), where Z, Y and n have the meanings (e), X indicates a grouping responsible for chelating the zinc atom of enzymes, enkephalinase and ACE, and may be selected from the group which comprises a mercaptomethyl; hydroxamic acid; an N-carboxyalkyl of the formula (f), wherein R3 represents a benzyl lower alkyl radical, or a benzyl lower alkoxy radical; phosphorus-containing derivatives of the formula (g) or (h).
Patent DE-69011628-T2 (DE)
Inventor: PEGLION JEAN LOUIS
IPC: A61P25/20
Filed: 1990-11-07
Granted: 1995-03-30
Abstract: Compounds of formula I    <IMAGE>  (I)  in which m represents an integer from 0 to 5, n represents an integer from 1 to 2, p is equal to 0, 1 or 2, X, Y and Z, which may be identical or different, each represent a hydrogen atom, a halogen atom, a linear or branched alkyl radical, a trifluoromethyl radical, an alkoxy radical, an alkylthio radical or a hydroxyl radical, and R represents a 2-benzofuranyl or 2,3-dihydro-2-benzofuranyl radical (it being possible for each to be substituted on the benzene ring), a 2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-2-yl radical, a 4-oxo-4H-chromen-2-yl radical (optionally substituted on the benzene ring), a benzocyclobutenyl radical of formula A or an indanyl radical of formula B:     <IMAGE> (A)   <IMAGE> (B)  (in which: R1 and R2, which may be identical or different, each represent a hydrogen atom, a halogen atom, a trifluoromethyl radical, an alkyl radical, an alkoxy radical, a hydroxyl radical, a hydroxyalkyl radical or an alkylthio radical, or together form a methylenedioxy radical or an ethylenedioxy radical, and R3 represents a hydrogen atom or a linear or branched alkyl radical having 1 to 6 carbon atoms), or a radical of formula C:    <IMAGE> (C)  (in which R4, R5 and R6, which may be identical or different, each represent a hydrogen atom, a halogen atom, a trifluoromethyl radical, a hydroxyl radical, an alkyl radical, an alkoxy radical or an alkylthio radical, their optical isomers and their addition salts with a pharmaceutically acceptable organic or inorganic acid.
Patent DE-69011876-T2 (DE)
Inventor: MATTESKY HENRY
IPC: D06F75/38
Filed: 1990-01-12
Granted: 1995-04-13
Abstract: A laundry iron lubricating means is provided comprising a fabric substrate having a coating containing a lubrication agent. In the operation of the device, the hot laundry iron is run over the coated fabric with normal pressure. The lubrication provided by a single pass reduces iron drag by 20 to 50%, adequate for the ironing of at least one large garment without need for a second pass. The greater the sole temperature of the iron, the greater the drag reduction.
Patent DE-69012219-T2 (DE)
Inventor: KONG-CHAN JOSEPHINE LING YEE
IPC: A23L33/20
Filed: 1990-06-06
Granted: 1995-03-09
Abstract: Synthetic cheese products which are reduced in calories and animal fat are produced by combining protein derived from dry-powdered bland-flavored milk protein, vegetable protein, aged or non-aged low-fat or full-fat cheese, or mixtures thereof; water; cheese flavors; an emulsifying salt; an acidulant; adjuvant materials, if desired; and a fatty substance which is non-digestible, partially digestible, or lower in net caloric efficiency than butterfat, animal fat, or vegetable fat.
Patent DE-69012512-T2 (DE)
Inventor: HAYASE YOSHIO
IPC: C07D213/643
Filed: 1990-11-08
Granted: 1995-05-04
Abstract: A heterocyclic oxy-phenoxyacetic acid derivative of the formula: <CHEM>  wherein R is a pyridyl or quinoxalinyl group optionally bearing thereon not more than two substituents chosen from halogen and halo(lower)alkyl; R<1> and R<2> are each hydrogen or lower alkyl; and R<3> is -NR<4>R<5>, -NHR<6> or -OR<7> (in which R<4> and R<5> are each hydrogen or lower alkyl or, when taken together with the adjacent nitrogen atom, represent a saturated nitrogen-containing 5- or 6-membered heterocyclic group optionally having one additional ring hetero atom chosen from nitrogen, oxygen and sulfur, which may bear thereon not more than two lower alkyl groups; R<6> is lower cycloalkyl, substituted or unsubstituted aryl, or a saturated or unsaturated 5- or 6-membered heterocyclic group having at least one ring hetero atom chosen from nitrogen, oxygen and sulfur or a group of the formula: -NR<8>R<9> (in which R<8> and R<9> are each hydrogen or lower alkyl or, when taken together, represent a lower alkylidene group); and R<7> is hydrogen, lower alkyl, lower alkoxy, substituted or unsubstituted aryl(lower)alkyl, substituted or unsubstituted aryloxy(lower)alkyl, halo(lower)alkyl, hydroxy(lower) alkyl or lower alkoxy(lower)alkyl), or its salt, which is useful as a herbicide, and including processes for its production.
Patent DE-69019263-T2 (DE)
Inventor: YOSHIMURA HIROSHI
IPC: F16H59/00
Filed: 1990-08-23
Granted: 1995-11-02
Abstract: A line pressure control system for an automatic transmission including a multiple shift stage transmission gear mechanism having a plurality of power transmitting paths of different speed ratios, line pressure control device for controlling a line pressure for frictional elements of the transmission gear mechanism associated with each other to establish a desirable shift gear stage, shift period detecting means for detecting a time period for a shift operation accomplished in terms of operation of the frictional element controlled by the line pressure, first compensating device for controlling the line pressure in terms of a learning control in a manner that the time period for the shift operation is controlled to a target value, abnormality detecting device for detecting an abrupt change such as turbine speed raising, depression or driving torque depression in operating condition of the transmission, and second compensating device for compensating the line pressure prior to compensation of the line pressure by the first compensating means when the abrupt change is detected. The torque shock can be effectively obviated during shift operation.
Patent DE-69021888-T2 (DE)
Inventor: GIRAULT HUBERT
IPC: G01N27/40
Filed: 1990-12-03
Granted: 1996-04-11
Abstract: A photo-ablation technique is used to create apertures (4) in a layer (2) of electrically insulating material and allow electrically conducting material (3) exposed through the apertures to create a microelectrode. The microelectrode can be used for assay methods and in an assay unit.
Patent DE-69030695-T2 (DE)
Inventor: WYMAN PAUL ADRIAN
IPC: A61K31/435
Filed: 1990-08-13
Granted: 1998-01-08
Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: <CHEM>  in which Z is a heterocyclic group <CHEM> in which Q represents a 3-membered divalent residue completing a 5-membered aromatic ring and comprises one or two heteroatoms selected from oxygen, nitrogen and sulphur, or three nitrogen atoms, any amino nitrogen being substituted by a C1-2 alkyl, cyclopropyl or propargyl group, and any ring carbon atom being optionally substituted by a group R1; or a group <CHEM> in which A1, A2 and A3 complete a 5-membered aromatic ring and A1 is oxygen or sulphur, one of A2 and A3 is CR2 and the other is nitrogen or CR3, or A2 is oxygen or sulphur, one of A1 and A3 is CR2 and the other is CR3; and R1, R2 and R3 are independently selected from hydrogen, halogen, CN, OR4, SR4, N(R4)2, NHCOR4, NHCOOCH3, NHCOOC2H5, NHOR4, NHNH2, NO2, COR4, COR5, cyclopropyl, C2-5 straight chain alkenyl, C2-5 straight chain alkynyl or C1-5 straight chain alkyl optionally terminally substituted with OR4, N(R4)2, SR4, CO2R4, CON(R4)2 or one, two or three halogen atoms, in which each R4 is independently hydrogen or C1-3 alkyl and R5 is OR4, NH2 or NHR4; or in which Z is a group -C(R7)=NR6 in which R6 is a group OR8, where R8 is C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, a group OCOR9 where R9 is hydrogen or R8, or a group NHR10 or NR11R12 where R10, R11 and R12 are independently C1-2 alkyl and R7 is hydrogen or C1-4 alkyl, subject to the proviso that when R6 is a group OCOR9 or NHR10, R7 is C1-4 alkyl.
Patent DE-69032127-T2 (DE)
Inventor: BUREL GILLES
IPC: G06T3/40
Filed: 1990-12-06
Granted: 1998-07-02
Abstract: PCT No. PCT/FR90/00888 Sec. 371 Date Jul. 25, 1991 Sec. 102(e) Date Jul. 25, 1991 PCT Filed Dec. 6, 1990 PCT Pub. No. WO91/08546 PCT Pub. Date Jun. 13, 1991.The method of picture compression consists: in processing a current displaced pixel block in the picture to be compressed by using a network of N neurons, 1 to N, disposed in a single plane, each neuron having a number of inputs equal to the dimension of the blocks extracted from the picture, and such that, after a learning phase during which the network has auto-organised so that the neurons represent most probable input values, each neuron receives on its inputs, at the same instant, the pixels of the current block and outputs a signal, or potential, dj, which is positive and is all the lower the nearer is the state of the corresponding neuron j to the state of the inputs ei, in coding the current pixel block through a code associated with the neuron j whose potential dj is minimal. The invention applies, in particular, to the compression of television pictures.
Patent DE-69033046-T2 (DE)
Inventor: ISHIHARA HIDESHI
IPC: G06T5/00
Filed: 1990-01-25
Granted: 1999-12-23
Abstract: An image processing system, comprising: a camera for taking a picture image of an object and producing a corresponding picture image signal; a binary discrimination circuit for converting the picture image signal into a binary signal; a memory unit for storing the binary signal; and feature extracting circuit for extracting a geometric feature of the picture image by processing the binary signal. Preferably, the feature extracting circuit comprises: an edge detection circuit having a hardware structure; and an arithmetic processing unit for computing, through a software process, geometric features from a graphic image included in the picture image of the object according to data on edge addresses. Thus, the processing speed is increased and the size and cost of the system is reduced by carrying out edge detection and address data collection requiring a large amount of processing work by means of a dedicated hardware circuit and carrying out arithmetic and other processes by means of software. Further, since the software of its arithmetic unit can be easily modified, the versatility of the processing work can be improved, and the range of application of the system can be broadened.
Patent DE-69110806-T2 (DE)
Inventor: KUSS GEORGE E
IPC: A23L27/10
Filed: 1991-08-02
Granted: 1995-11-30
Abstract: A method for treating vegetable oil to provide the natural flavor of peanut oil, olive oil and sesame oil is provided. In the method, a natural flavored oil is heated to a temperature of at least about 150 DEG F (at least about 65.6 DEG C). An inert gas is conducted through the oil while maintaining the oil at a natural flavor volatilization temperature of at least about 150 DEG F (at least about 65.6 DEG C) to provide an inert gas flavorant stream containing natural volatile flavor components. A vegetable oil is provided at a temperature less than the natural flavor volatilization temperature. The inert gas flavorant stream is conducted through the vegetable oil while maintaining the vegetable oil at a temperature less than the volatilization temperature of the flavored oil so as to deposit natural flavorant components in the vegetable oil to provide a vegetable oil having the derived natural flavor.
Patent DE-69119872-T2 (DE)
Inventor: REMPE PETER
IPC: C05F11/04
Filed: 1991-03-11
Granted: 1996-10-31
Abstract: A plant growing substrate is defined, which comprises peat and is manufactured by a high compression of peat into a shaped body, which is then minced. The compression is limited to 10:1 or slightly lower, preferably about 9:1, and the compressed peat bodies are, after the compression, minced into dices of a size of about 8 x 8 x 10 mm. Prior to the compression, the growing substrate is admixed with a fertilizer, as follows, calculated in kgs per m<3> of the ultimate growing substrate, i.g. after watering, viz.: 2-6 kg lime, 1-3 kg Dolomit, 1-2 kg Blåkorn (NPK 12-5-14), 0,1-0,3 kg FTE (micro fertilizing agents).
Patent DE-69122264-T2 (DE)
Inventor: BELLEAU BERNARD
IPC: C07D473/18
Filed: 1991-11-12
Granted: 1997-02-06
Abstract: This invention relates to novel substituted 1,3-oxathiolanes and substituted 1,3-dithiolanes of formula (1) wherein X is S, S=O, or SO2; Y is O, S, S=O, or SO2; R1 is hydrogen, trisubstituted silyl, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted aralkyl, or substituted or unsubstituted C1-16 acyl; and R2 is a purine or pyrimidine base or an analogue or derivative thereof; and pharmaceutically acceptable derivatives thereof. This invention also relates to processes for preparing these compounds, intermediates useful in their preparation, to pharmaceutical compositions containing them and to the use of these compounds as antiviral agents.
Patent DE-69127630-T2 (DE)
Inventor: GALARDY RICHARD
IPC: C07C237/22
Filed: 1991-11-21
Granted: 1998-04-09
Abstract: Compounds of the formulas   <IMAGE> (1)  or  <IMAGE> (2)  wherein each R1 is independently H or alkyl (1-8C) and R2 is alkyl (1-8C) or wherein the proximal R1 and R2 taken together are -(CH2)p- wherein p=3-5; R3 is H or alkyl (1-4C); R4 is fused or conjugated unsubstituted or substituted bicycloaryl methylene; n is 0, 1 or 2; m is 0 or 1; and x is OR5 or NHR5, wherein R5 is H or substituted or unsubstituted alkyl (1-12C), aryl (6-12C), aryl alkyl (6-16C); or X is an amino acid residue or amide thereof; or X is the residue of a cyclic amine or heterocyclic amine; Y is selected from the group consisting of R7ONR6CONR6-, R62NCONOR7-, and R6CONOR7-, wherein each R6 is independently H or lower alkyl (1-4C); R7 is lower alkyl (1-4C) or an acyl group; and wherein -CONR3- is optionally in modified isoteric form are inhibitors of matrix metalloproteases.
Patent DE-69129316-T2 (DE)
Inventor: WINCN JOHN M
IPC: H03K3/03
Filed: 1991-09-24
Granted: 1998-11-19
Abstract: A complementary metal oxide semiconductor, single, phase-lock loop decoding apparatus allows extraction of a clock signal from Manchester-encoded data. A filter couples a phase-frequency detector to a voltage-controlled oscillator. Output of the voltage-controlled oscillator is fed back through a scaling circuit to the phase-frequency detector which is used to lock on to the reference signal. First, the reference signal is provided from an established reference frequency from a crystal-controlled oscillator having 0.01% resolution. A multiplexer selects the external clock reference in response to a select signal and directs the clock signal to the reference input of the phase-lock loop. The phase-lock loop is operated to lock onto the reference voltage. The phase-lock loop has a narrow bandwidth, fast acquisition time because of time constants established by the filter and the voltage-controlled oscillator. Upon receipt of a Manchester-encoded signal, the preamble portion of the signal is selected by use of the multiplexer and directed to the reference input of the detector. The phase-lock loop, in response to a control signal, suspends operation at a known transition until a corresponding transition in the preamble occurs. The phase-lock loop is started in a synchronized fashion with the reference signal and has a nominal frequency equal to that of the phase-lock loop. Therefore, the phase-lock loop is able to accurately track and lock onto the reference voltage within the few bit times of the preamble even though it has the narrow bandwidth. Thereafter, decoding data by use of an extracted clock, 5 MHz components of the data will not appreciably affect the operation of the phase-lock loop allowing accurate decoding of the signal. By completion of data, the multiplexer reselects the reference in anticipation of receipt of another data packet. The phase-frequency detector is sensitive to both phase and frequency and use of a charge pump in the detector allows operation of the phase-lock loop to be halted without appreciably affecting voltage levels into the voltage-controlled oscillator without adversely affecting any timing circuits such as one-shot timers used in the decoding circuit.
Patent DE-69132548-T2 (DE)
Inventor: BUCHANAN CHARLES MICHAEL
IPC: C08G63/02
Filed: 1991-11-26
Granted: 2001-06-28
Abstract: This invention relates to binary blends of cellulose esters and aliphatic-aromatic copolyesters, cellulose esters and aliphatic polyesters as well as ternary blends of cellulose esters and/or aliphatic polyesters and/or aliphatic-aromatic copolyesters and/or polymeric compounds as well as fibers, molded objects, and films prepared therefrom.
Patent DE-69132629-T2 (DE)
Inventor: BROWNING JEFFREY
IPC: A61P37/00
Filed: 1991-06-27
Granted: 2002-04-18
Abstract: This invention relates to lymphotoxin- beta , a lymphocyte membrane type protein. This protein is found on the surface of a number of cells, including phorbol ester (PMA) stimulated T cell hybridoma II-23.D7 cells. This invention also relates to complexes formed between lymphotoxin- beta  and other peptides such as lymphotoxin- alpha  and to complexes comprising multiple subunits of lymphotoxin- beta . These proteins and complexes are useful in holding LT- alpha  formed within the cell on the cell surface where the LT- alpha /LT beta  complex may act as an inflammation regulating agent, a tumor growth inhibiting agent, a T cell inhibiting agent, a T cell activating agent, an autoimmune disease regulating agent, or an HIV inhibiting agent. Furthermore, the antitumor activity of the LT- alpha /LT- beta  complex may be delivered to tumor cells by tumor infiltrating lymphocytes (TILs) transfected with the gene for LT- beta .
Patent DE-69201892-T2 (DE)
Inventor: SCHLECHT KLAUS
IPC: A23F5/24
Filed: 1992-01-09
Granted: 1995-08-17
Abstract: Process for preparing a soluble instant coffee powder in which an extraction liquid is caused to circulate countercurrentwise through extraction cells, the liquid extract obtained being filtered and then centrifuged before being concentrated and then converted into a powder, in which, during this centrifuging phase, the oil contained in the liquid extract is separated in order to be reintroduced into the soluble coffee powder.
Patent DE-69209942-T2 (DE)
Inventor: UCHIDA TOSHIHIRO
IPC: A61K9/16
Filed: 1992-09-04
Granted: 1996-09-05
Abstract: When a powdered extract of Kampo medicine is encapsulated as such in hard capsules, the pharmaceutical effects of the Kampo medicine cannot be fully achieved, since the dissolution of the content of the hard capsules requires a long period of time. Therefore, the present invention aims at providing Kampo medicine hard capsules having good dissolution properties. The present invention provides a process for producing Kampo medicine hard capsules which comprises compacting Kampo medicine extract powder, mixing magnesium stearate with the compacted Kampo medicine extract powder and filing the mixture into gelatin hard capsules. It is preferable that the weight ratio of the magnesium stearate to the Kampo medicine powdered extract ranges from 0.5/100 to 3/100. Furthermore, it is preferable that said Kampo medicine is selected from Oren-gedoku-to, Sho-saiko-to, Ninjin-to, San'o-shashin-to, Mao-bushi-saishin-to, Anchu-san, Keishi-bukuryo-gan, Byakko-ka-ninjin-to, Shakuyaku-kanzo-to and Sairei-to.
Patent DE-69220761-T2 (DE)
Inventor: ALEWIJNSE CORNELIS
IPC: A22C15/00
Filed: 1992-12-08
Granted: 1998-02-26
Abstract: Rod for hanging objects thereon in a stable manner, for example in order to hang sausages thereon which are to be smoked in a space. Those objects must hang "free" with as large a part of their surface as possible, and the bar may not be very heavy. A rod according to the invention consists of stainless steel, is hollow and has a perpendicular cross section which has the form of a polygon with sides which have been indented from the outside inwards. <IMAGE>
Patent DE-69220967-T2 (DE)
Inventor: KIMURA KOICHI
IPC: F16H61/02
Filed: 1992-04-23
Granted: 1997-11-27
Abstract: An oil passage (120) is provided in an axially central portion of a spool (7) which is received within a valve housing (1) and rotatively driven by a pulse motor (6), and oil passages (121-125) passed diametrically through the spool (7) and connected to said oil passage (120), so that a hydraulic pressure from an input port (13) connected to a hydraulic pressure source (S) is selectively supplied to the oil passages (121-125) for selectively engaging and disengaging frictionally engaging elements of an automatic transmission. An axially acting load provided by the hydraulic pressure is received by a thrust bearing (10) mounted at an end of the spool (7). The supply of oil from the axial portion of the spool enables no side force to be applied, thereby reducing the frictional force and to enhance the sealability between the valve housing (1) and the spool (7). <IMAGE>
Patent DE-69227381-T2 (DE)
Inventor: CARRANO JAMES ALFRED
IPC: A01K1/00
Filed: 1992-02-10
Granted: 1999-07-01
Abstract: A livestock sorting system (10) is provided with an entrance (11) having an identification sensor (13-15) for identifying designated livestock passing therethrough, and first and second aisles (18, 20) extending from the entrance. A gate (52) has a first position (FIG. 2) providing communication of the entrance with the first aisle, and a second position (FIG. 3) providing communication of the entrance with the second aisle. An automatic control actuates the gate between the first and second positions in response to the identification sensor. <IMAGE>
Patent DE-69303103-T2 (DE)
Inventor: OXLEY JEFFERY ALLEN
IPC: A22C13/00
Filed: 1993-03-26
Granted: 1996-12-05
Abstract: A shirred fibrous casing (28) article composed of shirred portions (28A,28B), containing about 20% to about 30% moisture by total casing weight, spliced together and retained in an overwrap (38) wherein a flag (58) which identifies the splice location between the shirred portions is extended radially through the overwrap. <IMAGE>
Patent DE-69315699-T2 (DE)
Inventor: ZABLOCKI JEFFERY
IPC: A61P7/02
Filed: 1993-08-27
Granted: 1998-04-09
Abstract: This invention relates to compounds having the following formula   <IMAGE>   or a pharmaceutically acceptable salt thereof which are useful in the inhibition of platelet aggregation, to pharmaceutical compositions including the compounds, and to a method of inhibiting platelet aggregation in mammals by administering such compounds and compositions.
Patent DE-69323642-T2 (DE)
Inventor: BLART ERROL
IPC: C07D207/16
Filed: 1993-04-09
Granted: 1999-09-09
Abstract: The subject of the present invention is a reagent and a process useful for cleaving a functional group protected, on the occasion of an organic synthesis, by an alkoxycarbonyl group from the latter. This reagent is defined in that it contains:     a) an aqueous phase, b) a catalyst containing at least one element from Column VIII of the periodic classification of the elements, the said element from Column VIII of the periodic classification being maintained in the aqueous phase by complexation with at least one water-soluble coordination agent,   c) a water-soluble nucleophilic compound.   Application to organic synthesis.