baber/WOPTO huggingface dataset:
Patent EP-1458883-B1 (EP)
Inventor: HANASHIRO KAZUHIKO
IPC: A61P43/00
Filed: 2002-12-13
Granted: 2007-05-16
Abstract: Methods for screening agents effective against diabetes or preventing the onset of diabetes, in particular Type 2 diabetes, are provided. In one aspect of the invention, the method encompasses assaying for PAI-1 activity in the presence of a candidate agent; and correlating a decrease in PAI-1 activity relative to when the candidate agent is absent with the presence of a potential agent effective against diabetes. Alternatively, E2F activity is detected, an increase in E2F activity reflecting a decrease in PAI-1 activity. Also provided are methods for inhibiting PAI-1 activity, pharmaceutical agents and compositions.
Patent EP-1457031-B1 (EP)
Inventor: BURY EMMANUEL
IPC: H04M1/27453
Filed: 2002-12-13
Granted: 2010-09-08
Abstract: The call forwarding system has a user profile for each registered user, comprising the terminals (10,11) and determining and updating the accessibility status of each registered terminal. The call server (2) establishes a call with one of the registered users terminal, depending on the accessibility of the registered users terminals, following the priority attributed to each of the terminals.
Patent EP-1551591-B1 (EP)
Inventor: MCCRINK EDWARD J
IPC: F16L9/02
Filed: 2002-07-01
Granted: 2011-06-15
Abstract: The present invention provides seam-welded, air hardenable steel tubes, methods of manufacturing seam-welded air hardenable steel tubes, tube mills for practicing such methods and applications for using seam-welded, air hardenable steel tubing of the present invention.
Patent EP-1348751-B1 (EP)
Inventor: DINO DAVID
IPC: C09K8/08
Filed: 2003-02-19
Granted: 2007-01-24
Abstract: This invention relates to aqueous-based oil well drilling fluids containing a starch polymer derived from a starch having an amylose content of at least 50% by weight. The starch polymers provide high temperature fluid loss performance while having a minimum impact on viscosity build when incorporated into well drilling fluids. They may also be used in other applications for which cellulosic polymers have heretofore been employed because of their high temperature tolerance and minimum impact on rheological properties compared to conventional starch polymers.
Patent EP-1342445-B1 (EP)
Title: Wiping mop
Inventor: SALMON DIRK
IPC: B25G1/04
Filed: 2003-03-04
Granted: 2008-05-21
Abstract: The wiping apparatus (1), particularly for cleaning surfaces, comprises a clamping device (4) for accommodating at least one wiper textile (2), one work surface (3) and a movably connected handle (7). The clamping device has a clamp position (5) which is elongated in the area of the front edge of the work surface. The handle is connected via a spring arrangement (6) capable of producing a set-back force.
Patent EP-1424162-B1 (EP)
Inventor: HEESEMANN JUERGEN DIPL-ING
IPC: B24B41/00
Filed: 2003-09-23
Granted: 2007-09-12
Abstract: Processing machine comprises a machine frame (2) and a processing element (3) movably arranged via at least one drive shaft (5). One drive shaft with a movable bearing arrangement (13) is coupled to the machine frame and the processing element. The movable bearing arrangement has at least two roller bearings (16a,16b,19a,19b) coupled to each other and consisting of a first roller bearing coupled to the drive shaft and a second roller bearing arranged on the machine frame. The roller bearings have a common connecting bearing shell supporting the roller body of the coupled roller bearings and rotating and/or moving backward and forward so that the roller body is kept in motion.  Independent claims are also included for:  (1) Movable bearing arrangement; and  (2) Process for mounting a rotating shaft with a movable bearing arrangement.
Patent EP-1384488-B1 (EP)
Inventor: GOLDENBERG MILTON DAVID
IPC: A61K47/48
Filed: 1993-04-02
Granted: 2009-09-02
Abstract: A therapeutic application for organ- and tissue-targeting antibodies conjugated with a toxic agent is for the ablation of certain normal cells and tissues as part of another therapeutic strategy, such as in bone marrow ablation with antibodies against bone marrow cells of particular stages of development and differentiation, and in the cytotoxic ablation of the spleen in patients with lymphoma or certain immune diseases, such as immune thrombocytopenic purpura.
Patent EP-1416089-B1 (EP)
Inventor: VANHONACKER PATRICK
IPC: E01B21/00
Filed: 2003-09-22
Granted: 2006-05-24
Abstract: The railway track has a rail (11) fixed to the sleepers at regular intervals and an enclosure to cover the rail on both sides. The enclosure (18) has two flexible support profiles (14) fixed to the foot of the rail and extending between the sleepers. Alternatively, the rail sections can have concrete casings to allow use of prefabricated sections.
Patent EP-1346817-B1 (EP)
Inventor: JESSBERGER THOMAS
IPC: B29C65/06
Filed: 2003-02-24
Granted: 2004-10-20
Abstract: A vibrating tool (3) has a vibration direction (7) and is pressed (9) perpendicular to this direction onto a component (1) to be vibrated. Vibration is transmitted from the tool onto the component to be vibrated via relief-like recesses (5) or raised areas in the component welding surface (8).  An Independent claim is also included for a vibration transmitting tool for the process which has raised areas (6) or recesses corresponding to recesses or raised area in the component to be vibrated.
Patent EP-1483538-B1 (EP)
Inventor: PLATELL OVE
IPC: F24S90/00
Filed: 2003-01-31
Granted: 2010-07-28
Abstract: A plant for tempering a building, including an energy storage unit formed by ground heat exchangers coupled in parallel and each including a heat insulated leg and a non-insulated leg in thermal contact with surrounding soil. The heat exchangers are included in a circulating circuit for a circulation fluid which includes a circulation pump and room temperature keeping devices. The energy storage unit has a continuously varying temperature in a depth direction from a cold end to a warm end. The flow direction in the ground heat exchangers is controlled by a reversing valve such that for a warm keeping function, circulation fluid is received from the warm end and for a cool keeping function, circulation fluid is received from the cold end. The circulation pump is controlled such that the circulation flow brings about a temperature difference between the inlet and outlet of the ground heat exchangers that is constant with a value that can be calculated with the aid of the properties of the ground and the actual components.
Patent EP-1480797-B1 (EP)
Inventor: SCHROEDER FRIEDRICH
IPC: D04H1/58
Filed: 2003-02-27
Granted: 2010-11-17
Abstract: The invention relates to devices for the production of a non-woven (2) consisting of fibrous particles, comprising a pneumatic fractionating device (8) and a forming substrate (24) on which a fractionated flow of particles (9) can be arranged in such a way that relatively small particles are disposed in a lower and upper outer layer and relatively large particles are disposed in a middle layer (31) in said non-woven (2). A group of rollers (20) is arranged in a device on a first end section (10) of the fractionated particle flow containing the smallest particles and a conveyor belt (18) circulating around said group of rollers is arranged in a higher position. The fraction mixture can be fed by the conveyor belt to the group of rollers embodied in the form of a homogenizing unit which successively spreads partial flows (25,26,27) onto the forming substrate. In another device, one group of rollers (43) is provided on an end section of the particle flow containing the largest particles, in addition to an inclined screening device (40) which is arranged downstream from the fractionating device (8) and which conducts the larger particles to the group of rollers(43) acting as a homogenizing unit.
Patent EP-1483251-B1 (EP)
Inventor: REGUEIRO-REN ALICIA
IPC: A61K31/724
Filed: 2003-03-11
Granted: 2009-12-23
Abstract: The present invention relates to compounds useful in the treatment of cancer or other proliferative diseases represented by formula I: wherein: Q is selected from the group consisting of M is O, NR9, or CR10R11; X is O or NH; and the R groups are as defined, and therapeutic compositions containing them alone or in combination with other therapeutic agents useful in the treatment of cancer or other proliferative diseases.
Patent EP-1482911-B1 (EP)
Inventor: YATES KENNETH M
IPC: A23L19/00
Filed: 2003-03-06
Granted: 2007-10-17
Abstract: Substantially dry mixture having solid-containing complex carbohydrate and a water-soluble pharmaceutical auxiliary is dispersible in water. The dry mixture can also contain simple sugar and starch. A dispersible, or soluble, mixture having solid-containing complex carbohydrate, originated or derived from a processed plant, and processes of preparation of the mixture. The processed plant can be Aloe vera.
Patent EP-1478623-B1 (EP)
Inventor: LACOUX XAVIER
IPC: C07D207/44
Filed: 2003-02-26
Granted: 2011-03-23
Abstract: Heterobifunctional functional coupling agents (I), comprising peptide derivatives containing at least one 8-amino-3,6-dioxa-octanoic acid unit and aminooxy and maleimide functional groups, are new. Heterobifunctional functional coupling agents of formula (I), comprising peptide derivatives containing at least one 8-amino-3,6-dioxa-octanoic acid unit and aminooxy and maleimide functional groups, are new. W = NH-(CH2)2O(CH2)2-OCH2CO; A = (W')p-CO-(CH2)u-Mal (a), (W')p-CO-CH-((CH2)rNH-(W')p-CO-(CH2)u-Mal)2 (b) or (W')p-CO-CH(-(CH2)rNH-(W')p-CO-CH(-(CH2)r-NH-(W')p-CO-(CH2)u-Mal)2)-(CH2)q-NH-(W')p-CH(-(CH2)r-NH-(W')p-CO-(CH2)u-Mal)2 (c); D = group (a), (b), (c) or CO-(CH2)u-Mal (d); Mal = maleimide; Y = group terminated by CONH2 and inert with respect to the remainder of the molecule; W' = COCH2O-(CH2)2O(CH2)2-NH; n = 0-3; m, o = 0-3; p = 1-4; q = 0-3; r = 2-5; s = 0 or 1; t = 1-7, and u = 2-10. Independent claims are also included for: (1) new activated intermediates (II) comprising (I) and a molecule (II') having at least one surface aldehyde and/or ketone function before conjugation; (2) new activated intermediates (III) comprising (I) and 1-8 (preferably 1-4) molecule(s) (III') having at least one surface thiol function before conjugation; and (3) new conjugates (IV) comprising (I) bonded to (II') and to 1-8 molecule(s) (III').
Patent EP-1565142-B1 (EP)
Inventor: LINKER III PAUL MEANS
IPC: A61B19/00
Filed: 2003-05-23
Granted: 2011-04-13
Abstract: L'invention concerne un article absorbent pouvant comprendre une couche extérieure, une doublure côté corps et une couche centrale absorbante disposée entre la couche extérieure et la doublure. Ledit article peut également comprendre une paire de régions de rabat faisant partie d'une région de taille avant, et une paire de rabats arrière dotés d'un élément de fixation mécanique faisant partie d'une région de taille arrière. L'article peut comprendre, en outre, une région d'entrejambe reliant les parties de taille avant et de taille arrière, une zone de réception comprenant un matériau de base et un premier groupe d'éléments de fixation discrets incorporés dans ledit matériau de base. Ce premier groupe d'éléments de fixation discrets peut comprendre au moins un premier élément de fixation discret possédant une hauteur de profil, le matériau de base possédant une hauteur de profil supérieure à celle du premier élément de fixation discret. La zone de réception peut être associée à la couche extérieure dans la région de taille avant de l'article entre les régions de rabat avant.
Patent EP-1509273-B1 (EP)
Inventor: PEPIN HENRY J
IPC: A61M25/00
Filed: 2003-04-30
Granted: 2009-01-07
Abstract: An intravascular catheter having an elongate shaft that is entirely non-magnetically responsive and at least partially radiopaque, including a reinforcement layer. The reinforcement layer may comprise a non-magnetically responsive radiopaque metal, such as a multi-strand Tungsten braid. The improved shaft of the present invention is compatible with x-ray and MRI visualization techniques, and may be incorporated into a wide variety of intravascular catheters such as guide catheters, diagnostic catheters, balloon catheters, etc.
Patent EP-1508335-B1 (EP)
Inventor: NISHIMURA EISAKU
IPC: A61K31/20
Filed: 2003-05-27
Granted: 2011-09-28
Abstract: L'invention concerne une composition contre des bactéries parodontales, qui présente une grande sécurité sans provoquer aucun effet secondaire et qui fait preuve d'un excellent effet de suppression de bactéries parodontales sans affecter la croissance de micro-organismes indigènes non pathogènes dans la cavité orale, ainsi que des aliments, boissons et eaux dentaires contre des bactéries parodontales. Une composition contre des bactéries parodontales est mélangée avec une faction de cacao contenue dans de la pâte de cacao, un extrait d'eau chaude de la fraction de cacao, des polyphénols provenant de la fraction de cacao ou des acides gras libres provenant de la fraction de cacao en tant qu'ingrédient actif. Ensuite, la composition contre des bactéries parodontales ainsi obtenue est ajoutée à des aliments, boissons ou eaux dentaires contre des bactéries parodontales. De préférence, la fraction de cacao décrite ci-dessus est du cacao et/ou de la pâte de cacao. De préférence, les acides gras libres décrits ci-dessus contiennent au moins un élément choisi dans le groupe comprenant de l'acide palmitique, de l'acide stéarique, de l'acide oléique et de l'acide linoléique.
Patent EP-1487920-B1 (EP)
Inventor: LAUK URS
IPC: C08K5/18
Filed: 2003-03-13
Granted: 2012-02-15
Abstract: The present invention relates to a compound of formula (I) wherein R<SUB>1 </SUB>is a radical of formula (II) R<SUB>2 </SUB>is -NH<SUB>2 </SUB>or a radical of formula (II), R<SUB>3 </SUB>and R<SUB>4 </SUB>are each independently of the other hydrogen, hydroxy, -NH<SUB>2 </SUB>or a radical of formula (II), R<SUB>5 </SUB>is hydrogen, halogen or -X-(CH<SUB>2</SUB>)<SUB>n</SUB>-Y, wherein X is a direct bond, -O- or -S-, Y is -OH or -OSO<SUB>3</SUB>H and n is a number from 0 to 6, with the proviso that at least one of the radicals R<SUB>3</SUB>, R<SUB>4 </SUB>and R<SUB>5 </SUB>is not hydrogen, to a process for the preparation thereof and to the use thereof in a method of producing mass-coloured plastics or polymeric colour particles.
Patent EP-1565647-B1 (EP)
Title: Einem aggregate-riementrieb einer brennkraftmaschine zugeordnetes reibradgetriebe für ein gesondertes nebenarggregat
Inventor: LEMBERGER HEINZ
IPC: F02B67/04
Filed: 2003-10-15
Granted: 2011-10-12
Abstract: Für ein einem Aggregate - Riementrieb einer Brennkraftmaschine zugeordnetes Reibradgetriebe für ein gesondertes Nebenaggregat wird vorgeschlagen, dass ein gesteuert bewegliches Reibrad (5) des Reibradgetriebes (2) in einer maschinenseitig einem jeweiligen Triebrad (4) der Brennkraftmaschine oder eines sonstigen Aggregates oder einem reibradgetriebeseitigen Antriebsrad (6) des Nebenaggregates (3) in einem jeweiligen Umschlingungsbereich des Riemens (1′′) benachbart angeordneten Führungseinrichtung (8) längs eines zu einer Drehachse (9) des jeweiligen Trieb - oder Antriebsrades (4, 6) äquidistanten Kreisbogenabschnittes relativ zum Antriebsrad (6) oder zur Riemenaussenseite (1′) im jeweiligen Umschlingungsbereich mittels einer Steuereinrichtung (7) für eine Zu - und Abschaltung des Nebenaggregates (3) lageveränderbar angeordnet ist.
Patent EP-1551481-B1 (EP)
Inventor: GOOSSENS BJORN OLAF
IPC: A61M5/32
Filed: 2003-10-16
Granted: 2009-04-08
Abstract: Injection syringe (1) comprises liquid container (3), needle (2) with needle mount (8), and blocker (14). The liquid container has an outlet opening (4). The needle with needle mount is secured in the outlet opening of the liquid container. The blocker is designed to block the needle mount in the outlet opening. The blocker can be unblocked by needle mount with needle retracted into the liquid container.
Patent EP-1523522-B1 (EP)
Inventor: NULL VOLKER KLAUS
IPC: C08L23/16
Filed: 2003-07-16
Granted: 2010-04-21
Abstract: The invention relates to a composition having a ethylene-propylene-diene rubber component and a Fischer-Tropsch derived process oil. The process oil preferably has a flash point of above 260° C. and an evaporation loss at 107° C. during 22 hours of less than 0.05 wt %.
Patent EP-1567647-B1 (EP)
Inventor: RANK KENNETH BRUCE
IPC: C12Q1/37
Filed: 2003-11-17
Granted: 2007-10-03
Abstract: The present invention is directed to novel soluble substrates for γ-secretase. More particularly, the invention provides a soluble fusion polypeptide with a Notch segment containing the γ-secretase-dependent cleavage sites (γ and ε) fused to a NusA protein. Methods and compositions for making and using such a fusion protein are disclosed.
Patent EP-1556588-B1 (EP)
Inventor: JOUANNY PHILIPPE
IPC: F01P7/16
Filed: 2003-10-28
Granted: 2012-01-18
Abstract: The invention concerns a system for cooling an engine, in particular a heat engine (10), cooled by circulating a coolant and a cooling radiator (18) cooled by outside ambient air. The engine forms part of a primary loop (2) and the cooling radiator (18) forms part of a secondary loop (4). The same fluid circulates in both loops. The primary loop and the secondary loop are in heat-exchanging relationship with each other via an intermediate exchanger (26) traversed by both the coolant of the primary loop (2) and by the coolant of the secondary loop (4). The invention is applicable to motor vehicles.
Patent EP-1573994-B1 (EP)
Inventor: BOASSON ERIK
IPC: H04J1/12
Filed: 2003-12-19
Granted: 2007-06-06
Abstract: Systems and methods for efficiently conveying one or more communication channels over a transmission medium. Communication is effected by transforming an incoming digital bit stream into a Hermite-Gaussian information stream that includes a plurality of Hermite-Gaussian packets. This transformation is accomplished through the use of a plurality of Hermite-Gaussian basis functions. The Hermite-Gaussian information stream is then transmitted over the transmission medium. More particularly, digital bit streams carried on one or more incoming channels may be in the form of binary "on" and "off" bits. These digital bits are converted into a plurality of Hermite-Gaussian waveform components which together comprise a Hermite-Gaussian packet. The conversion process maps each of respective incoming digital bits to a corresponding one of a group of Hermite-Gaussian functions. Optionally, this mapping process could be implemented sequentially, or in parallel form, such that a first bit is mapped to a first Hermite-Gaussian function, a second bit is mapped to a second Hermite-Gaussian function, and so on, until the Nth Hermite-Gaussian function is reached, whereupon the process cycles back to the first Hermite-Gaussian function. In any case, the presence of a "1", "on", or "high" bit enables the corresponding Hermite-Gaussian function, whereas the presence of a "0", "off", or "low" bit disables the corresponding Hermite-Gaussian function. When enabled, each respective Hermite-Gaussian function specifies the transmission of a corresponding Hermite-Gaussian waveform component. Each waveform component is substantially confined within a range of values in both the frequency and time domains.
Patent EP-1578594-B1 (EP)
Inventor: CHAPMAN MARTIN C
IPC: B29D30/56
Filed: 2003-12-05
Granted: 2006-06-21
Abstract: A method and apparatus for balancing a tire during a retreading operation includes measuring the radial runout the buffed tire casing and applying the gum layer and tread strip to compensate for variances in runout. The gum layer is applied so that an overlap or smear is formed at the relative low portion of the casing. The tread strip is applied with the joint at the same low portion in cases where the low portion has a relatively large variance, or at another location if the variance is small or other low portions exist. In addition, the thickness of the gum layer and tread strip may be controlled for further compensation of the runout variance.
Patent EP-1585822-B1 (EP)
Inventor: YAVER DEBBIE
IPC: C12P1/00
Filed: 2003-11-18
Granted: 2012-01-25
Abstract: The present invention relates to methods for producing a biological substance, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the biological substance, wherein the fungal host cell comprises a first nucleic acid sequence encoding the biological substance operably linked to a second nucleic acid sequence comprising a promoter variant selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, and SEQ ID NO: 12; and a subsequence thereof; and hybrid and tandem promoters thereof; and (b) isolating the biological substance from the cultivation medium. The present invention also relates to the isolated promoter variants and to constructs, vectors, and fungal host cells comprising the promoter variants operably linked to nucleic acid sequences encoding biological substances.
Patent EP-1606171-B1 (EP)
Inventor: USSEN BAKHYTBEK
IPC: B65D5/20
Filed: 2003-12-01
Granted: 2010-01-27
Abstract: An universal semi-automatic foldable box is generally disclosed comprising a box body (1) having a bottom panel (2), and two or more side walls (5), and the corresponding number of soft sheets (9) and spring strips (11). Each spring strip is connected to the bottom panel and at least one side wall. The side walls are connected to the bottom panel such that they can unfold and rise and the sheets form foldable connecting portions for connecting the side walls, and the spring strips serve to unfold the box flat. The spring strip has the property of remaining straight when unfolded but self-folding when it is slightly bent from its straight condition. The spring strips may be provided as an integral part of the box, or alternatively, may be a separate piece, which then can be attached by the user to the side walls of the box. The box body can be of different size and shape, such as for example square, sphere, rectangular, hexagonal, octagonal, and the like, and can be made of any material. A box of this invention can be utilized for a variety of different storage applications and can be used in any kinds of environment in which a box would be used.
Patent EP-1562086-B1 (EP)
Inventor: JEANNERET SEBASTIEN
IPC: G06K19/07
Filed: 2004-02-04
Granted: 2011-11-23
Abstract: The mechanism has an intermediate movable part (32) with two parts connected by a connection unit. The unit has a friction mechanism arranged such that one part can move with friction with respect to the other part when a power reserve indicator attains its end position and an elastic unit arranged such that it is reinforced when the indicator attains its another end position.
Patent EP-1457186-B1 (EP)
Inventor: KOCH REINHARD
IPC: B65D83/08
Filed: 2004-03-09
Granted: 2007-06-27
Abstract: The dispenser is assembled of two identical shells (10, 20), forming a case with an octagonal cross section. The shells (10, 20) are joined by inserting pins protruding from the lower edges of the corners positioned diagonally opposite each other into small cases provided at the remaining corners. The pins are wider at their bases preventing them from sliding completely into the cases, resulting in a narrow gap between the shells (10, 20). The material can be pulled through the gap, serving as an outlet.
Patent EP-1506923-B1 (EP)
Inventor: KIRCHER WILLI
IPC: B65B37/20
Filed: 2004-07-06
Granted: 2008-05-28
Abstract: The dispenser for measured amounts of powders comprises a tank with outlets at the bottom. A swiveling partition is mounted in the tank which divides it into two chambers. This allows accurate amounts of material to be dispensed from one chamber while the other is being filled.
Patent EP-1645418-B1 (EP)
Inventor: STEIGER MARTIN
IPC: B41J2/175
Filed: 2004-10-11
Granted: 2012-04-11
Abstract: The adapter (1) for an ink cartridge comprises a filter element (6) which in the frame overlap region incorporates a barrier zone (17) not letting through liquids. An independent claim is also included for an ink holding unit with the proposed adapter.