Patent SG-11201906837P-A (SG)
Title: A drug monitoring tool
Inventor: NELSON MICHAEL
IPC: C07K14/755
Filed: 2018-01-23
Abstract: RemoteServer Ecosystem Monitoring System 180 Activation Toolkit 155 Scanner 160 Processors) 165 Receiver 170 Display/User Interface 175 Drug Monitoring Tool 150 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 02 August 2018 (02.08.2018) WIPO I PCT omit IIl °nolo oimIE (10) International Publication Number WO 2018/140373 Al 1-1 N O 00 O C I Infusion I Pump 140 (51) International Patent Classification: GOOF 19/00 (2018.01) GOON 7/00 (2006.01) A61K 38/37 (2006.01) CO7K 14/755 (2006.01) A61K 38/48 (2006.01) Cl 2N 9/64 (2006.01) (21) International Application Number: PCT/US2018/014772 (22) International Filing Date: 23 January 2018 (23.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/451,391 27 January 2017 (27.01.2017) US (71) Applicant: SHIRE HUMAN GENETIC THERAPIES, INC. [US/US]; 300 Shire Way, Lexington, MA 02421 (US). (72) Inventors: NELSON, Michael; 300 Shire Way, Lexing- ton, MA 02421 (US). PICHLER, Roman; 300 Shire Way, Lexington, MA 02421 (US). SPOTTS, Gerald; 300 Shire Way, Lexington, MA 02421 (US). (74) Agent: MEYERS, Thomas, C. et al.; Brown Rudnick Llp, One Financial Center, Boston, MA 02111 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). = (54) Title: A DRUG MONITORING TOOL 100 FIG 1 Biological i Collector 135 Patient Samples 110 (57) : Embodiments of the present disclosure relate to a drug monitoring tool. The drug monitoring tool comprises a data receiver and an interactive user interface. The data receiver is configured to receive a pharmacokinetic (PK) profile of a patient. The interactive user interface is configured to display, to the patient, a time-varying therapeutic plasma protein level of the patient. The time- varying therapeutic plasma protein level is based on an administered dose of a clotting factor VIII and the PK profile of the patient. [Continued on next page] WO 2018/140373 Al MIDEDIMOMMIONEEMOMMMOIMIIMEINIMMIS Published: — with international search report (Art. 21(3))