baber/WOPTO huggingface dataset:
Patent NZ-251730-A (NZ)
Title: 4,4,7-triphenyl-n-acylperhydroisoindole derivatives and medicaments
Inventor: ACHARD DANIEL
IPC: A61P9/02
Filed: 1993-04-08
Abstract: PCT No. PTC/FR93/00352 Sec. 371 Date Oct. 11, 1994 Sec. 102(e) Date Oct. 11, 1994 PCT Filed Apr. 8, 1993 PCT Pub. No. WO93/21155 PCT Pub. Date Oct. 28, 1993.This invention relates to novel perhydroisoindole derivatives of general formula (I),    <IMAGE>  (I)  wherein radicals R are phenyl radicals optionally 2- or 3-substituted by a halogen atom or a methyl radical; R1 is optionally substituted phenyl, cyclohexadienyl, naphthyl, indenyl or optionally substituted heterocyclyl; R2 is H, halogen, OH, alkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkyloxy, alkylthio, acyloxy, carboxy, optionally substituted alkyloxycarbonyl, benzyloxycarbonyl, amino or acylamino; R3 is optionally 2-substituted phenyl; R4 is OH or fluorine when R5 is H, or R4 and R5 are OH or R4 and R5 together form a bond; isomeric forms and mixtures thereof; optionally salts thereof where applicable; and preparation thereof. The novel derivatives are particularly useful as P substance antagonists.
Patent NZ-268826-A (NZ)
Title: Protein encapsulated gas microspheres and their use in ultrasonic imaging
Inventor: LAMBERT KAREL J
IPC: A61K49/22
Filed: 1994-07-01
Abstract: Encapsulated gas microspheres having improved pressure resistance and stability are made by: mixing an aqueous solution of a filmogenic protein such as human serum albumin with a water insoluble gas such as perfluoropropane and subjecting the mixture to ultrasonic or mechanical cavitation in the absence of oxygen in an apparatus that is closed to the atmosphere.
Patent NZ-269855-A (NZ)
Title: Powder inhaler comprising a tubular member connected to a chamber and a single restriction there between
Inventor: HOERLIN ERNST
IPC: A61M15/06
Filed: 1994-07-25
Abstract: The invention concerns an inhaler device (1) having a hollow tubular member (2, 102, 402) connected to a chamber (5, 105, 405). The tubular member has a first opening (3, 103, 203) at one end through which air can be sucked and the chamber (5, 105, 405) has a hole (4, 104, 204) therein for entry of air. When air is sucked through the first opening, air enters the chamber through the hole swirls and moves towards the first opening (3, 103, 203). To maintain or increase the swirling effect of the air a single restriction (10, 110) is arranged between the opening and the hole (4, 104, 204). A powdered substance (8) within the chamber is picked up by the swirling air within the chamber and is uniformly and finely divided by the swirling effect of the air. The effect can be enhanced by adding a movable element (6) such as a ball inside the chamber (5) and/or by providing a central core element (112, 412) inside the chamber. <IMAGE>
Patent NZ-273073-A (NZ)
Title: Bicyclic heterocyclic sulphonamide and sulphonic acid ester derivatives and pharmaceutical compositions thereof
Inventor: YOSHINO HIROSHI
IPC: C07D403/12
Filed: 1994-09-08
Abstract: Novel bicyclic heterocyclic sulfonamide and sulfonic ester derivatives represented by general formula (I) having an antitumor activity and a reduced toxicity, pharmacologically acceptable salts thereof, and a process for producing the same; wherein ring A represents an optionally substituted mono- or bicyclic aromatic group; ring B represents an optionally substituted 6-membered unsaturated hydrocarbon ring or 6-membered unsaturated heterocyclic group containing one nitrogen atom; ring C represents an optionally substituted 5-membered heterocyclic group containing one or two nitrogen atoms; W represents a single bond or -CH=CH-; X represents -NR<1>- or oxygen; Y represents carbon or nitrogen; Z represents -NR<2>- or nitrogen; and R<1> and R<2> represent each independently hydrogen or lower alkyl. <CHEM>
Patent NZ-281480-A (NZ)
Title: Monomeric igg antibody purification
Inventor: SHADLE PAULA J
IPC: C07K16/00
Filed: 1995-02-21
Abstract: This invention relates to the application of hydrophobic interaction chromatography combination chromatography to the purification of antibody molecule proteins.
Patent NZ-295238-A (NZ)
Title: Immunogenic compositions characterised by the carrier being a hydrophobic solvent in the absence of a hydrophilic phase
Inventor: NEW ROGER RANDAL CHARLES
IPC: A61K47/44
Filed: 1995-11-14
Abstract: An immunogenic composition comprising an immunogen solubilised, or otherwise distributed, in a hydrophobic solvent in the absence of a hydrophilic phase. Preferably, the immunogenic composition is provided as an oral vaccine.
Patent NZ-314568-A (NZ)
Title: Estrogen related diseases using controlled release systems of low dosage androgens
Inventor: LABRIE FERNAND
IPC: A61K/
Filed: 1992-06-29
Abstract: A pharmaceutical composition comprising an androgenic steroid selected from medroxyprogesterone acetate and megestrol acetate, dispersed within a sustained-release binder may be used in the treatment of breast and endometrial cancer, osteoporosis and endometriosis.  The binder maintains circulating serum levels of the androgenic steroid between 1.0 and 50.0 nanomoles per litre during a time period beginning 48 hours after administration and ending at least 28 days after administration.  The androgenic steroid has a Ki value of less than 2x10-8M for the androgen receptor and an androgen receptor mediated inhibitory effect on the growth of human breast cancer ZR-75-1 cells, which reaches half maximal value at a concentration below 3.0 nanomoles per litre.  The androgenic steroid also has no visible masculinizing activity.
Patent NZ-324882-A (NZ)
Title: Refining element has a refining surface having with bars and grooves with specific geometry characteristics
Inventor: VIRVING NILS
IPC: B02C2/10
Filed: 1996-12-04
Abstract: PCT No. PCT/SE96/01594 Sec. 371 Date Jun. 17, 1998 Sec. 102(e) Date Jun. 17, 1998 PCT Filed Dec. 4, 1996 PCT Pub. No. WO97/23291 PCT Pub. Date Jul. 3, 1997Refining elements are disclosed for use in refiners in which the refining elements comprise a refining surface with a plurality of raised bars alternating with a plurality of grooves. The raised bars at the inlet of the refining path have a first spacing and form a first angle with respect to a radius or generatrix defining the refining path and the plurality of raised bars at the outlet of the refining path have a second spacing and form a second angle with respect to the radius or generatrix, the first angle being between about 50 DEG  and 85 DEG  and the second angle being between about -25 DEG  and +25 DEG , and the first spacing being greater than the second spacing.
Patent NZ-336622-A (NZ)
Title: A pipe coupling formed from FRP as skein on rotating former
Inventor: CRAIG DAVID DUNCAN
IPC: F16L21/06
Filed: 1999-07-07
Abstract: A pipe coupling and/or methods of manufacture thereof which comprises of a circumferentially discontinuous tubular casing adapted to accommodate circumferential expansion and contraction and a tubular elastomeric gasket within an inwardly facing annular channel in the casing. A fibre reinforced plastic (FRP) clamping band (2) fitted to the outward face of the casing, the clamping band spanning substantially but not entirely the circumference of the casing and having the fibres (16) therein oriented circumferentially. A tension means (8) connects the ends of the clamping band and is manipulable to draw the ends of the band together. A further aspect provides for a method of manufacturing a pipe coupling including the steps of winding a skein (26) of resin impregnated fibres between and over a pair of end holders,	applying the centre of the skein to the outwardly facing surface of a circumferentially discontinuous substantially tubular casing (optimally at a point substantially opposite the discontinuity), wrapping each end of the skein along the circumference of the casing, and retaining the skein in that position until the resin has solidified.
Patent NZ-500953-A (NZ)
Title: Cyanoamidines as cell proliferation inhibitors
Inventor: OTTOSEN ERIK RYTTER
IPC: A61K31/44
Filed: 1998-05-15
Abstract: A compound of formula (I), or their tautomeric forms, the attachment to the pyridine being in the 2-, 3- or 4-position.  R1 stands for one or more substituents which can be the same or different and are selected from the group consisting of: hydrogen, halogen, amino, trifluoromethyl, nitro, cyano, carboxy and alkyl, alkoxy, or alkoxycarbonyl, the C-content of which can be from 1 to 4; Q stands for C4-C9 divalent hydrocarbon radical which can be straight, branched, saturated or unsaturated; X stands for methylene, oxygen, sulphur or NH, and R stands for hydrogen or for one or more substituents which can be the same or different and are selected from the group consisting of: hydroxy, amino, halogen, trifluoromethyl, cyano, nitro, carboxy, carbamoyl, methylenedioxy and alkyl, alkoxy, alkylthio, alkylamino or alkoxycarbonyl, the C-content of which can be from 1 to 4; and pharmaceutically acceptable, non-toxic salts and N-oxides thereof. The compounds show activity in inhibiting undesirable cell proliferation in skin cells and cancer cells.
Patent NZ-501091-A (NZ)
Title: Use of dihydroxyquinoline compounds to extend the shelf life of products of mammals and fish
Inventor: SAMUELS WINSTON A
IPC: A23K1/16
Filed: 1998-07-10
Abstract: The shelf life of a meat product derived from an animal selected from the group consisting of ruminant mammals, swine and fish is extended by feeding to the animal a diet of feed comprising a substituted 1,2-dihydroquinoline compound.
Patent NZ-507258-A (NZ)
Title: Automatically sealing medical valve for syringes and the like
Inventor: LOPEZ GEORGE A
IPC: A61M39/14
Filed: 2000-09-29
Abstract: A method of establishing a fluid flow path through a medical connector having an outer housing, with a hollow interior, a proximal end and a distal end.  The method involves positioning a seal within the interior which has a proximal end and a distal end and a wall with inner and outer surfaces defining a passage through the seal along an axial centreline extending through the proximal and distal ends.  The seal has an axially uncompressed position in which the passage is closed at the seal proximal end, obstructing fluid flow through the connector.  At least a portion of the seal fills a radial cross-section of the housing at or near the housing proximal end in the uncompressed position.  At least one of the surfaces has alternately radially inward and radially outward extending surfaces with respect to the centre line while the seal is in the uncompressed position.  The seal also has an axially compressed position in which the passage is open at the seal proximal end and the passage is unobstructed.  The seal further has a first axial height (H1) when in its uncompressed position and a second axial height (H2) when in its compressed position. The seal is compressed within the housing by inserting a medical implement through the proximal end of the housing into the housing interior.  The end of the medical implement contacts the seal at the proximal end of the seal upon insertion of the implement into the housing interior. This changes the height of the seal from H1 to H2, where H1 is greater than H2, and opens the passage through the seal along the centreline when the seal is in its compressed position thus establishing fluid flow through the housing proximal end to the housing distal end.
Patent NZ-507724-A (NZ)
Title: Laminate and package made therefrom
Inventor: KOCHER PATRICK N
IPC: B65D81/20
Filed: 1999-05-11
Abstract: A laminate includes: a. a first, substantially gas-impermeable film; b. a second, delaminatable film; and c. a third, gas-permeable film. The second film is positioned between the first and third films and the laminate is capable of delaminating within the second film when the laminate is subjected to a delaminating force. A portion of the delaminatable film thus remains bonded to the gas-permeable film after delamination.
Patent NZ-515662-A (NZ)
Title: Storage system
Inventor: BELL LESLIE STEPHEN
IPC: A47B46/00
Filed: 2000-04-28
Abstract: A storage system (10) is described in which one or more receptacles (14) for storing articles are pivotally supported on a support shaft (12).  Each receptacle (14) is provided with a bracket (16) arranged to support the receptacle and coupled to the shaft (12) in a manner to allow the bracket (16) to pivot about the shaft (12).  In this way, each receptacle (14) can be individually pivoted about a shaft (12) to allow access to that receptacle and any article stored therein.  The storage system (10) makes more efficient use of space and can be accessed more easily than a conventional chest of drawers or cupboard.
Patent NZ-517842-A (NZ)
Title: Vented bag with a label affixed over apertures on the bag
Inventor: GRKOVIC VELJKO
IPC: B65D33/01
Filed: 2002-03-15
Abstract: A container (10), such as a thermoplastics inner bag within a kraft paper outer bag, suitable for a particulate material is disclosed, wherein, as a venting feature to have a venting mode and a non-venting mode so as to favour one way gas passage outwardly of the container (10), there are slits in the wall overlaid with a label (11) and other slits that are not in register with those of the wall. The label (11) is affixed so as to be able, in use, in a venting mode, under the influence of a gas from within the container (10), to separate or billow outwardly sufficiently to allow a venting of at least some of that gas out of the slits of the label (11), and, in a non-venting mode, to assume a substantially unseparated or non-billowing form to restrict ingress of gas into the container (10) from outside of the label (11) and restrict or at least reduce passage through the venting feature of any particulate material from the container (10).
Patent NZ-518361-A (NZ)
Title: A method for detecting hermetic defects in high temperature superconducting tapes and wires using visible changes in colour
Inventor: LONG NICHOLAS
IPC: G01N33/20
Filed: 2002-04-15
Abstract: A method for detecting hermetic defects in a high temperature superconductor (HTSC) which comprises an HTSC core and an outer layer is disclosed, wherein the method includes causing a tracer gas or liquid such as ammonia, H2O, halogen or an alcohol to penetrate the HTSC core of the conductor and subsequently exposing the conductor either to an indicating chemical such as indophenol blue which undergoes a visible change in colour on contact with the tracer gas or liquid at hermetic defects in the outer layer of the conductor to expose the hermetic defects, or to an environment which will cause any tracer gas or liquid contacting the environment at hermetic defects in the outer layer of the conductor to undergo a visible change to expose the hermetic defects
Patent NZ-521731-A (NZ)
Title: Urination apparatus
Inventor: LEVINSON ORDE
IPC: A61F5/455
Filed: 2001-03-29
Abstract: The present invention relates to urination apparatus for urine sample collection for testing of urine, waste urine collection for disposal of urine resulting from urination away from toilets, and simplification of urination by women without sitting on a toilet. A urine sample collection apparatus (100B) has a tubular portion (3) having a coupling (60A) in the side thereof formed for releasably mounting an open topped urine sample collection container (70) thereto in a direction extending generally away from the axis of said tubular portion. The apparatus also has a urine receiving receptor (1B) with a surface portion (4B) extending from a rim (5B), bounding an inlet surface which is symmetrical about the axis of said tubular portion, to an aperture (2B) from which said tubular portion extends in a direction generally away from said inlet surface. The edge of the rim (110'B) on the side corresponding to said coupling is displaced along the axis of the tubular portion further from the aperture than the opposing edge of the rim (110'A).
Patent NZ-523574-A (NZ)
Title: Tubular fleece retention net for biological harvesting
Inventor: GALE GARY
IPC: A01K14/00
Filed: 2003-01-10
Abstract: A fleece retention net (1) for fitting to a fleece bearing animal (S) during biological fleece harvesting. The net (1) includes a net body (2) of resiliently extendable mesh fabric (10) for enclosing at least a substantial portion of the fleece (F) of the animal (S) when fitted to the body of the animal (S). The net body (2) has holes (12) for the reception of the legs of the animal (S) there through.
Patent NZ-525937-A (NZ)
Title: Electronic game for computer or slot machine
Inventor: ELLIS BEN
IPC: G07F17/32
Filed: 2001-10-16
Abstract: A device is disclosed for playing an electronic game for interactive play. The device includes a display screen which has a plurality of indicia initially displayed in a plurality of rows and columns in two dimensions. The rows and columns of indicia collectively form a predetermined two dimensional display, where at least one of the columns spins in a vertical plane in response to a spin command. At the completion of spinning in one or more vertical planes, and contingent upon a required result, at least one of the rows spins in a horizontal plane. At the conclusion of the spinning of the rows, a player obtains a random indicia or a combination of indicia. The displayed indicia is compared to at least one predetermined winning indicia to determine the outcome of the game, where each indicia on each row transform from two dimensions into three dimensions during spinning in the vertical or horizontal planes.
Patent NZ-526380-A (NZ)
Title: Shock-wave meat treatment for tenderising and/or killing microbes
Inventor: LONG JOHN B
IPC: A23L13/70
Filed: 2001-12-07
Abstract: A method of tenderizing meat and/or killing microbes in meat is achieved by using, individually or in combination, a capacitor discharge chamber of shortened height, a drum-head on which the meat sits during treatment and which is located at the upper end of the capacitor discharge chamber, meat supporting structure which substantially holds the meat in place on the drum-head during capacitor discharge, an indexing carousel for delivery the meat to a location above the capacitor discharge chamber and for transporting the treated meat to a discharge location, an improved negative or compression or rarefaction wave and the combination of shock wave treatment with other operations.
Patent NZ-529682-A (NZ)
Title: Biologically active methylene blue derivatives
Inventor: BROWN STANLEY BEAMES
IPC: A61M25/10
Filed: 2002-05-30
Abstract: Disclosed are phenothiazinium compounds of formula (1) wherein: A and B are each independently formula (2), in which Z is CH2, O, S, SO2, NH, NCH3, NC2H5, NCH2CH2OH or NCOCH3 and R1 and R2 are each independently linear or branched CnH2nY as defined; and XP- is a counteranion and P is 1,2 or 3. Compounds of formula (1) are disclosed for use in the treatment of micro-organism infections, photo-activated sterilization of surfaces and for photodynamic therapy (PDT) of conditions where treatment requires removal of unwanted tissue or cells.
Patent NZ-530912-A (NZ)
Title: A microorganism with protease decomposing proteins recalcitrant to proteolysis
Inventor: DOI HIROYASU
IPC: C12N1/21
Filed: 2004-02-02
Abstract: An isolated or purified Streptomyces sp. 99-GP-2D-5 or a bacterium derived therefrom capable of producing a protease, the protease capable of decomposing a protein recalcitrant to proteolysis such as a perchloric acid-soluble protein PSP and/or an abnormal prion protein; a protease capable of decomposing a protein recalcitrant to proteolysis obtained from the Streptomyces sp.; and a method of treating a material containing the recalcitrant protein using the Streptomyces sp. or the protease.
Patent NZ-541733-A (NZ)
Title: Use of the enantiomer (1S,2R) of milnacipran for the preparation of a medicament
Inventor: DEREGNAUCOURT JEAN
IPC: A61P9/00
Filed: 2004-02-16
Abstract: Disclosed is the use of a mixture of enantiomers of milnacipran (Z(±)-2-(aminomethyl)-N,N- diethyl-1-phenylcyclopropanecarboxamide) or pharmaceutically acceptable salts thereof, such mixture being substantially pure in the (1S,2R) enantiomer for the preparation of a drug intended for the treatment or the prevention of conditions or disorders in a patient that can be managed by double inhibition of serotonin (5-HT) and noradrenaline (NA) reuptake while limiting the risk of cardiovascular disturbances.
Patent NZ-547156-A (NZ)
Title: Attenuation of A/E pathogen virulence by modulating expression of NleA
Inventor: FINLAY BRETT
IPC: C12Q1/68
Filed: 2004-10-29
Abstract: Disclosed is a bacterium, or a preparation thereof, wherein the bacterium is an A/E pathogen and comprises a deletion mutation in the bacterial genome in a nucleotide sequence that comprises at least 75% sequence identity to one or more of SEQ ID NOs: 1-3 (nleA), wherein the deletion mutation inactivates expression of the gene encoded by any one of SEQ ID NO:1-3. Also disclosed are methods of attenuating the virulence of an A/E pathogen comprising mutating a nleA gene, methods of treating or preventing infection by an A/E pathogen, and methods of screening for a compound that attenuates the virulence of an A/E pathogen.
Patent NZ-549219-A (NZ)
Title: Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof
Inventor: FUSHIMI NOBUHIKO
IPC: A61K31/7042
Filed: 2005-03-03
Abstract: Disclosed are nitrogenous fused-ring derivatives represented by general formula (I) or pharmacologically acceptable salts thereof, wherein the substituents are disclosed within the specification. Also disclosed is the human SGLT inhibitory activity of the compounds of general formula (I). Accordingly, compounds of the present invention are useful as preventive or therapeutic agents for diseases attributable to hyperglycemia, such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, complications of diabetes, and obesity.
Patent NZ-551262-A (NZ)
Title: Alloy for making sacrificial anodes for use in galvanic protection
Inventor: MADDERN BRETT ALEXANDER
Filed: 2006-11-13
Abstract: An alloy which comprises from 0.30 to 0.6 per cent silicon plus or minus 5 per cent, 0.1 to 0.30 per cent iron plus or minus 5 per cent, 0.10 copper plus or minus 5 per cent, 0.10 per cent manganese plus or minus 5 per cent, 0.35 to 0.6 per cent magnesium plus or minus 5 per cent, 0.05 per cent chromium plus or minus 5 per cent, 0.15 per cent zinc plus or minus 5 per cent, 0.10 per cent titanium plus or minus 5 per cent, 0.05 maximum individual trace metals plus or minus 5 per cent, 0.15 per cent total trace metals plus or minus 5 per cent and the balance aluminium. Sacrificial anodes made form these alloys are used in the galvanic protection of non metallic water vessels, wherein the physical integrity of the anode is sacrificed through the dissolution of the anode into the bridging medium in order to maintain the physical integrity of the cathode.
Patent NZ-554695-A (NZ)
Title: Thiazolyl-dihydro indazoles
Inventor: BETZEMEIER BODO
IPC: A61K31/429
Filed: 2005-10-05
Abstract: Disclosed is a thiazolyl-dihydro indazole derivative of formula (1), wherein the substituents are as defined in the specification. Also disclosed are intermediates useful in preparing the above compound. Also disclosed is the use of the above compound for treatin cancer.
Patent NZ-564888-A (NZ)
Title: Turbine for a hydroelectric power station
Inventor: ROHDEN ROLF
IPC: F03B13/10
Filed: 2006-07-10
Abstract: A turbine is provided for a hydroelectric power station. The turbine has a rotor with a plurality of blades, with the rotor being arranged in front of a guide apparatus (in the flow direction). The pitch angle of the blades on the rotor is designed to be variable. The turbine is in the form of an upstream rotor turbine so that the blades have an afflux flow, which is substantially undisturbed by the turbine in the through-flow direction.