baber/WOPTO huggingface dataset:
Patent EA-001887-B1 (EA)
Title: Imino-aza-anthracyclinone derivatives for the treatment of amyloidosis
Inventor: CARUSO MICHELE
IPC: A61K31/439
Filed: 1998-01-09
Abstract: 1. A compound of the formula (1):   wherein: R1 is hydrogen, and lower alkyl; R2 is hydrogen, C1-4 alkyl, allyl, benzyl optionally substituted with one-three substituents, selected from the group comprising trifluoromethyl, C1-4 alkyl, C1-4 alkoxy, halo and hydroxy; pyridinomethyl, pyridinomethylcarbonyl; R3 is selected from the groups of hydroxyl, C1-4 alkoxy, benzyloxy, methylamino, or pyridinmethyloxy, 4-morpholinyl, 4-methylpiperazinyl, provided that  when R1 is methoxy group and R3 is hydroxy group, R2 differs from 4-pyridinmethyl, or a pharmaceutically acceptable salt thereof. 2. The compound of Claim 1, wherein R1 is selected from hydrogen and methoxy; R2 is hydrogen, methyl, allyl, benzyl, 3-bromobenzyl, 4-trifluoromethylbenzyl, 4-methoxybenzyl, 3,4-dimethoxybenzyl, 3,5-di-tert-butyl-4-hydroxybenzyl, pyridinemethyl, nicotinoyl; R3 is hydroxy, methoxy, ethoxy, benzyloxy, 4-pyridenemethyloxy, methylamino, 4-morpholinyl, 4-methylpiperazinyl, or a pharmaceutically acceptable salt thereof. 3. The compound of Claim 1, which is selected from 8-N-(3,4-dimethoxybenzyl) anthrazolone oxime, S-N-allylanthrazolone oxime, O-methyloxime S-N-allylanthrazolone, and anthrazalone O-ethyloxime, or a pharmaceutically acceptable salts thereof. 4. A process for preparing a compound of the formula (1), as defined in Claim 1, which process comprises: (a) reacting a compound of the formula (2)   wherein R1 and R2 are as defined in Claim 1, with a compound of the formula: R3-NH2 wherein R3 is as defined in Claim 1, and (b) optionally converting the thus obtained compound of the formula (1) into another compound of the formula (1); and/or (c) optionally converting the compound of the formula (1) to a pharmaceutically acceptable salt thereof. 5. The process of Claim 4, wherein in step (a) a compound of the formula (2) as defined in Claim 4, is reacted with a compound of formula R3-NH2.HA, wherein HA represents an inorganic acid, in an organic solvent in the presence of an organic or inorganic base. 6. A pharmaceutical composition, which comprises, as active ingredient, an effective amount of a compound of the formula (1) as defined in any of Claims 1-3, or a pharmaceutically acceptable salt thereof, in admixture with a pharmaceutically acceptable carrier or diluent. 7. A compound of the formula (1) as defined in any of Claims 1-3, or a pharmaceutically acceptable salt thereof for treating a human or an animal. 8. A compound of the formula (1) as defined in any of Claims 1-3, or a pharmaceutically acceptable salt thereof for producing a pharmaceutical composition for treating an AL amyloidosis disease, Alzheimer's disease, and Down's syndrome. 9. A method of treating a human or animal suffering from, or susceptible to, an amyloidosis disease, which comprises administering thereto an non-toxic and effective amount of a compound of the formula (1), as defined in any of Claims 1-3, or a pharmaceutically acceptable salt thereof.
Patent EA-002324-B1 (EA)
Title: Microparticle having a protein and an antibody absorbed thereon for preparing a pharmaceutical composition for intranasal administration
Inventor: CREMASCHI DARIO
IPC: A61K9/18
Filed: 1998-04-08
Abstract: 1. Use of a microparticle having a protein and an antibody adsorbed thereon for preparing a pharmaceutical composition for intranasal administration. 2. Use of a polymeric microparticle according to claim 1, characterised in that the protein is selected from the group comprising BSA, insulin, enkephalin, hormones, growth factors, cytokines, coagulation factors, polypeptides, antimicrobial agents and fragments thereof. 3. Use of a polymeric microparticle according to claim 1 or claim 2, characterised in that the antibody is an immunoglobulin selected from the group comprising IgM, IgA and IgG. 4. Use of a polymeric microparticle according to claim 3, characterised in that the immunoglobulin is specific for the protein. 5. Use of a polymeric microparticle according to any of claims 1 to 4, characterised in that the microparticles are microspheres of polymeric material. 6. Use of a polymeric microparticle according to claim 5, characterised in that the polymeric material is biodegradable. 7. Use of a polymeric microparticle according to claim 5, characterised in that the polymeric material is polystyrene. 8. Use of a polymeric microparticle according to any of claims 3 to 6, characterised in that the protein/immunoglobulin ratio is of from 1 to 15,000 mols of protein per mole of immunoglobulin. 9. Use of a polymeric microparticle according to any of claims 3 to 6, characterised in that the protein/immunoglobulin ratio is of from 1 to 5,000 mols of protein per mole of immunoglobulin. 10. Use of a polymeric microparticle according to any of claims 3 to 6, characterised in that the protein/immunoglobulin ratio is of from 1 to 100 mols of protein per mole of immunoglobulin.
Patent EA-006553-B1 (EA)
Title: Solid pharmaceutical compositions containing a 4-amino-3-substituted butanoic acid derivative, process for preparing the same by incorporating a humectant as a stabilizer
Inventor: AOMATSU AKIRA
IPC: A61K31/196
Filed: 1999-05-10
Abstract: The present invention provides a stabilized solid composition containing a 4-amino-3-substituted-butanoic acid derivative which can be obtained by incorporating a humectant as a stabilizer.
Patent EA-003717-B1 (EA)
Title: Automatic heat valve
Inventor: ROMANENKO NIKOLAY TROFIMOVICH
IPC: F16K17/40
Filed: 2002-06-11
Abstract: 1. An automatic heat valve comprising a body in the cavity of which a spring-loaded gate provided with a stopper and a latch is mounted against a through opening, the inner cavity of which is filled with an easily melted material, fixing the gate cylindrical rod is drawn out of the cavity, wherein the stopper is arranged on the side opposite to the spring, and the gate is a ball gate mounted with eccentricity relative to the axis of the through opening, characterized in that a circular turning is made in the body cavity into which the stopper and the latch are placed diametrically opposite to ball, the stopper is in the form of a washer with an open trapezoid cut, while the latch is provided with grooves connecting its cavity with the body cavity, the latch cavity is cylindrical, response to the rod cross-section, the rod has flat ends, the rod is deepened into the latch cavity to at least 0.25 of its diameter. 2. The automatic heat valve, characterized in that comprises a support washer having flexible pawls providing its insertion into the body cavity and subsequent locking and central circular rim which centers the spring.
Patent EA-008351-B1 (EA)
Title: Gas hydrate inhibitors
Inventor: RIVERS GORDON T
IPC: E21B37/06
Filed: 2003-09-02
Abstract: A method for inhibiting formation of hydrocarbon hydrates in mixtures of water and a hydrate-forming guest molecule involves adding a reaction product to the mixtures in an effective amount to inhibit formation of the hydrocarbon hydrates under conditions otherwise effective to form the hydrocarbon hydrates in the absence of the reaction product. The product is made by the reaction of first reactant that is an amine or polyamine, or alcohol or polyalcohol, with a second, aldehyde reactant and a third reactant that is an alcohol or polyalcohol or, an amide or polyamide. Preferably, if the first and third reactants are both an alcohol or both a polyalcohol, they are not the same. A non-limiting example of a suitable amine would be a fatty alkyl amine, while formaldehyde would be a non-limiting of a suitable aldehyde and polyacrylamide would be a suitable third reactant.
Patent EA-007246-B1 (EA)
Title: Net horse-cover as a fixing device for an urine collecting device placed on a horse
Inventor: FRINK MARTIN
IPC: A01K23/00
Filed: 2003-12-18
Abstract: The invention relates to a net horse-cover used as an easily used fixing device for an urine collecting device smoothly placed on a horse in such a way that it is easily replaceable. The inventive net horse-cover used as a fixing device consists of a net (1) which covers the major part of the horse body laterally extending to the lower torso line and is closed or can be closed on the horse breast (2). Said net horse-cover is mainly used for a flexibly suspended urine collecting device which makes it possible to obtain a natural conjugate estrogens mixture from urine of a pregnant mare.
Patent EA-015898-B1 (EA)
Title: Process for producing polymer blend in ionic liquid and polymer blends
Inventor: HOLBREY JOHN D
IPC: C08J3/00
Filed: 2005-03-25
Abstract: The present invention relates to a process for producing polymer blend utilizing ionic liquids for the dissolution of various polymers and/or copolymers, the formation of blends, and the reconstitution of polymer and/or copolymer solutions, and to the dissolution and blending of "functional additives" and/or various polymers and/or copolymers to form advanced composite materials.
Patent EA-010762-B1 (EA)
Title: Clothes dryer
Inventor: SCHUCK ROLF
IPC: D06F58/04
Filed: 2006-02-22
Abstract: In a front-loading clothes dryer, a horizontally pivotable door (4) is secured in its closed position against accidentally opening by a latching closure. Moreover, the door (4) is connected to a safety switch which cuts off or re-establishes power supply for the clothes dryer depending on whether the door is in the open or in the closed position. The object of the invention is to ensure that the switching function remains matched over the long term to the closure state of the door (4), as when the clothes dryer was manufactured. For that purpose, the functional elements (10 and 11) for the latching closure and safety switch are arranged in direct proximity to each other but functionally separated into a component (8) arranged on the door and a component (9) arranged on the casing.
Patent EA-014046-B1 (EA)
Title: A volumetric rotary machine with a bispherical chamber
Inventor: DIDIN ALEXANDER VLADIMIROVICH
IPC: F01C3/06
Filed: 2007-09-20
Abstract: A volumetric rotary machine (VRM) is invented, which working chamber is in the form of two overlapping spheres bounded by the inclined planes. The rotor is made in the form of a cylinder with a longitudinal through groove, with two pistons mounted in it, executing rotatory vibrations in the plane of the groove, overlapping the working chamber and creating a pressure difference when they are near the end points of vibration, i.e. when its speed relative to the rotor is minimal, and therefore the losses on friction and wear are minimal. As a result, the relatively cheap high-speed VRM comes out with high specific characteristics (the ratio of the power to the size and weight, the feed to the size), with potentially longer working life and reliability, with geometrically simple working surfaces (a plane on a plane, a sphere on a sphere). The widespread use of the VRM in multistage submersible pumps is planned.
Patent EA-015403-B1 (EA)
Title: Electrical switchgear unit such as a circuit breaker or a switch
Inventor: PREVIEUX LAURENT
IPC: H01H71/02
Filed: 2008-11-14
Abstract: The present invention relates to an electrical switchgear unit housed in a case and comprising at least one stationary contact and at least one movable contact supported by a contact support shaft, an opening and/or closing mechanism (8) of the movable contact(s) fitted in a support (13), said mechanism (8) comprising a manual operating handle (9) of the contact(s) fitted rotating around a toggle pin of the case, and a shaft called high-speed closing shaft (12) designed to keep the movable contact(s) in the open position, at the beginning of the manual closing operation of the handle and over a certain travel of the latter, by storing energy and to release the movable contact(s) after this travel of the handle so that the stored energy causes high-speed closing of the contacts. This device is characterized in that, on one of its side faces, the above-mentioned support (13) of the mechanism (8) comprises an opening (14) designed to accommodate at least a part of said high-speed closing shaft (12), the latter being thereby able to be inserted laterally at least partially into said support (13) prior to fixing of said shaft inside the case, and that the means for fixing said support (13) inside the case are located on one side of the mechanism (8) only with respect to the high-speed closing shaft (12).
Patent EA-015633-B1 (EA)
Title: Steel compositions for special uses
Inventor: PETELOT DANIEL
IPC: C22C38/18
Filed: 2007-06-07
Abstract: The invention concerns steels having excellent resistance over time, in a corrosive atmosphere due to oxidizing environments such as, for example, fumes or water vapour, under high pressure and/or temperature. The invention concerns a steel composition for special applications, said composition containing, by weight, about 1.8 to 11% of chromium (and preferably between about 2.3 and 10% of chromium), less than 1% of silicon, and between 0.20 and 0.45% of manganese. It has been found that it is possible to adjust the contents of the composition based on a predetermined model, selected to obtain substantially optimal properties with respect to corrosion in specific conditions of high temperature performances. Said model can involve as additive of as residue at least one element selected among molybdenum, tungsten, cobalt, and nickel.
Patent EA-016565-B1 (EA)
Title: Method for influencing the magnetic coupling between two bodies at a distance from each other and device for performing the method
Inventor: GOGICHEV VADIM
IPC: H01F21/08
Filed: 2008-05-15
Abstract: The invention relates to a method for influencing the magnetic coupling between two bodies (10, 12) at a distance from each other, characterized in that a controllable field displacement device (13) having a field displacement area is placed between the two bodies (10, 12) and that the magnetic field (11) present between the two bodies (10, 12) is displaced out of the field displacement area of the field displacement device (13) in a prescribed manner by corresponding actuation of the field displacement device (13).
Patent EA-017427-B1 (EA)
Title: Cyclone and sulphur granulation system
Inventor: TAN ZHONGCHAO
IPC: B04C3/06
Filed: 2008-06-03
Abstract: The invention describes a cyclone which includes a cylindrical housing and has an inner diameter D. An inlet is near a first end of the housing. A deflection member can be positioned within the first end or the second end of the housing, depending on whether the cyclone is uniflow or reverse flow. An outlet tube is positioned within and extends from a second end or the first end of the housing (depending on whether uniflow or reverse flow). A bunker is formed between the outlet tube and an inner wall of the housing in a uniflow design and between the deflection member and the housing in a reverse flow design, and collects particles separated from an inlet gas stream. A gap between the deflection member and the outlet tube has a length in the range of approximately 0.4*D to 0.8*D. The length of the bunker is approximately greater than or equal to 1.5*D.
Patent EA-021549-B1 (EA)
Title: Method for producing molds
Inventor: FROHN MARCUS
IPC: B22C1/22
Filed: 2009-05-22
Abstract: The invention relates to a method for producing cores and molds for the foundry industry, wherein a flowable fire-resistant primary molding material is provided; an acid is applied to the flowable fire-resistant primary molding material, thus obtaining an acid-coated fire-resistant primary molding material; a binder that can be cured by acid is applied to the acid-coated fire-resistant primary molding material, thus obtaining a fire-resistant primary molding material coated with a binder; the fire-resistant primary molding material coated with a binder is molded into a molded body, and - the molded body is cured, wherein the acid is a mixture of methane sulfonic acid and at least one further sulfur-free acid. The invention further relates to a mold material mixture as it is used in said method. With the method or the mold material mixture, casting molds can be produced having reduced emission of harmful compounds during casting.
Patent EA-022479-B1 (EA)
Title: Flavored thermoplastic composition and process for producing the same
Inventor: MACINNIS KARI L
IPC: A23L27/29
Filed: 2009-08-28
Abstract: The invention relates to a flavored thermoplastic composition and a process for producing the same. In one embodiment the invention relates to the flavored thermoplastic composition essentially comprising: (a) from 0.1 to 20 wt.% of one or more flavor enhancing agent which is heat stable and provides the taste component of flavor, (b) from 0.01 to 20 wt.% of one or more flavorant which is heat stable are provides the aromatic component of flavor, and (c) one or more thermoplastic polymer which may be formed by melt processing and which is selected from the group consisting of polyethylene, polypropylene and copolymers or terpolymers thereof, wherein (i) the thermoplastic polymer provides the migration of the flavor enhancing agent and flavorant without consuming, significantly destructing, masticating or fully or partially dissolving an article made from the flavored thermoplastic composition, and (ii) the flavor enhancing agent and flavorant are selected for thermal stability under the melt processing temperatures of the polymer; wherein the taste component of flavor and the aromatic component of flavor are released from the article made from the thermoplastic composition without its consuming, significantly destructing, masticating or fully or partially dissolving; and the flavor enhancing agent and flavorant are mixed throughout the thermoplastic polymer.
Patent EA-019045-B1 (EA)
Title: Nickel/lanthana catalyst for producing syngas
Inventor: MAMEDOV AGADDIN KH
IPC: B01J23/83
Filed: 2010-03-15
Abstract: The present invention relates to a nickel/lanthana (Ni/LaO) catalyst for producing syngas from a hydrocarbon feedstrearn that is prepared in situ by depositing nickel (Ni) on a lanthana (LaO) support by contacting said LaOsupport with an aqueous nickel-salt (Ni-salt) solution in the presence of an oxygen-comprising gas stream which is followed by reducing the deposited Ni. The catalyst of the present invention is characterized in that it can be continuously operated for more than 14 days in a process for producing syngas from a hydrocarbon feedstream without showing a significant loss of catalyst activity.
Patent EA-023692-B1 (EA)
Title: Master mixture composition including a peroxide
Inventor: LAIGNEL ANNE-YVONNE
IPC: C08L31/04
Filed: 2010-06-15
Abstract: The invention relates to a transparent master mixture that includes an ethylene copolymer and an ethylene monomer having a polar function (a) and a peroxide (b), characterized in that said composition includes from 5 to 30 wt.% of (b); from 70 to 95 wt.% of (a); and in that the copolymer (a) includes from 20 to 45 wt.% of ethylene monomer having a polar function. The invention also relates to a method for producing a master mixture composition including an organic peroxide. The method makes it possible to produce a composition useful for the cross-linking of polymers.
Patent EA-030161-B1 (EA)
Title: Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
Inventor: APT KIRK E
IPC: C12N15/82
Filed: 2009-03-19
Abstract: The present invention is related to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further related to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils and methods of using the isolated thraustochytrids, biomasses and microbial oils.
Patent EA-023727-B1 (EA)
Title: Disposable pants-type body waste handling article
Inventor: TAKINO SHUNSUKE
IPC: A61F13/496
Filed: 2008-09-03
Abstract: The invention is aimed at improving known clothing article for preventing discharging body fluid through legs openings even in case of sliding down a belt region of the clothing article while a diaper was on a user. A clothing article (1) of a disposable pants-type is provided with an intermediate element (3) in the perineal region passing in the longitudinal direction A and attached to a sheet element (11), forming inner surfaces of front and rear belt regions. The intermediate element (3) is provided with flaps (24) along its opposite side edges and free edges (40b) of corresponding flaps (24) have elastic elements (43) for the perineal region, attached thereto in a stretched state. The front and rear belt regions are provided with lower elastic elements (15b) along peripheral edges for leg's openings, attached thereto in a stretched state. The regions of side flaps (24), in which free edges (24b) of the flaps (24), developed in the transverse direction, overlap the bonded lower elastic elements (15b), are attached to corresponding inner surfaces of the front and rear belt regions.
Patent EA-025452-B1 (EA)
Title: System and method for remote sensing
Inventor: GONZALEZ MANUEL E
IPC: G01V11/00
Filed: 2011-11-11
Abstract: A system for monitoring conditions in a borehole and a method therefor. Well tubing and casing act as a conductive pair for delivering power to one or more downhole active sensors. At the surface, power and signal are isolated so that the same conductive pair may act to transmit the sensor signals to the surface. In an embodiment, the sensor signals are RF signals and the surface electronics demodulate the RF signals from the sensor power.
Patent EA-029912-B1 (EA)
Title: Method for processing ore-containing material and system for implementation thereof
Inventor: KESSLER MATTHIAS
IPC: B03C1/00
Filed: 2013-11-13
Abstract: The method according to the invention for processing ore-containing material is characterized in that the material is comminuted in at least one first mill, and the comminuted material is classified in a first classification into coarse and fine material. At least a part of the coarse material from the first classification is returned to the first mill and the fine material from the first classification is again classified in a second classification into coarse and fine material. The coarse material from the first classification is optionally subjected to a first sorting into a first valuable fraction and a first less valuable fraction. The first valuable fraction is returned to the first mill and the less valuable fraction is discarded, and the coarse material from the second classification is subjected to a second sorting into a second valuable fraction and a second less valuable fraction. The second valuable fraction is returned to the first mill and the second less valuable fraction is discarded and the fine material from the second classification is subjected to a third classification and then subjected to at least a third and/or fourth sorting.
Patent EA-029428-B1 (EA)
Title: METHOD AND APPARATUS FOR RECOVERING PLATINUM GROUP METALS (PGMs) AND FERROCHROME FROM PGM BEARING CHROMITE ORE
Inventor: NARHI LAURI
IPC: C22B34/32
Filed: 2014-03-25
Abstract: In a method for recovering platinum group metals (PGMs) and ferrochrome from PGM bearing chromite ore, a concentrate is prepared that contains most of PGMs and chromite of the ore and the concentrate is subjected to a heating step to dry and/or preheat the concentrate, after which the preheated concentrate is smelted under reducing conditions in a DC smelting furnace (14) to produce molten metal alloy containing the PGMs of the feed and molten slag containing the chromium of the feed. The molten slag is tapped from the smelting furnace (14) into an AC slag furnace (16), where iron and chromium are reduced to produce a ferrochrome alloy. PGMs are recovered from the metal alloy tapped from the smelting furnace (14) utilizing hydro-metallurgical processes.