baber/WOPTO huggingface dataset:
Patent CO-6612253-A2 (CO)
Title: Agentas y antagonistas fijadores de notch y metodos para el uso de los mismos
Inventor: GURNEY AUSTIN
IPC: A61K39/395
Filed: 2011-02-08
Abstract: El presente invento se relaciona con agentes fijadores de Notch y antagonistas de la proteína Notch y métodos para el uso de los agentes y/o antagonistas para el tratamiento de enfermedades como el cáncer. El presente invento suministra anticuerpos los cuales se fijan de manera específica a una región no fijadora de ligandos del dominio extracelular de uno o más receptores Notch humanos, como Notcb2 y/o Notch3, e inhiben el crecimiento tumoral. El presente invento además suministra métodos para tratar el cáncer, los métodos comprenden la administración de una cantidad terapéuticamente efectiva de un anticuerpo el cual se fija de manera específica a una región no fijadora de ligandos del dominio extracelular de una proteína receptora Notch humana e inhibe el crecimiento tumoral.
Patent CO-6382159-A2 (CO)
Title: Derivados bicíclicos de morfina-6-glucurónido, su preparación y su aplicación en terapéuticaqq
Inventor: DLUBALA ALAIN
IPC: C07H15/24
Filed: 2011-06-10
Abstract: La presente invención tiene por objeto los compuestos que responden a la fórmula (I) en la que: R1 representa un átomo de hidrógeno o un grupo alquilo(C1-C4), R2 representa un grupo hidroxilo, un grupo tiol, un grupo alquiloxi(C1-C4) o un grupo tioalquilo(C1-C4), y n es un número entero igual a 1 ó 2, en el estado de base o de sal de adición a un ácido así como en el estado de hidrato o de solvato. La presente invención pretende igualmente su procedimiento de preparación y su aplicación en terapéutica.
Patent CO-6481012-A2 (CO)
Title: Implemento para el cuidado oral que tiene mangos de componentes múltiples
Inventor: MOSKOVICH ROBERT
IPC: A46B5/02
Filed: 2012-05-29
Abstract: Un implemento para el cuidado oral que tiene un mango de componentes múltiples, y método de manufactura del mismo. La invención puede ser un implemento para el cuidado oral que tiene un mango que comprende al menos cuatro componentes construidos de diferentes materiales. La invención también puede ser un implemento para el cuidado oral que tiene un mango que comprende una estructura central construida de un primer material rígido y un cuerpo de mango alargado construido de un segundo material rígido, la estructura central dispuesta dentro de una ranura con salida del cuerpo de mango alargado; y una cubierta de agarre construida de un material resiliente que cubre una superficie frontal, una superficie posterior y una superficie de extremo proximal del cuerpo de mango alargado. La cubierta de agarre se puede usar para ocultar los agujeros con salida en el cuerpo de mango alargado que resulta de soportar la estructura central durante el moldeado por inyección del cuerpo de mango alargado alrededor de la estructura central.
Patent CO-6620061-A2 (CO)
Title: Métodos y sistemas para la colección y carga automática de un vehículo eléctrico en una estación de carga
Inventor: SARKAR REUBEN
IPC: B60L11/18
Filed: 2012-10-26
Abstract: La invención provee sistemas y métodos para conectar un vehículo eléctrico o vehículo eléctrico hibrido a una estación de carga. Se pueden proveer procesos de carga y acoplamiento automatizados. En algunas modalidades, la llegada y posición del vehículo pueden ser detectadas. El vehículo puede ser cargado con un brazo de carga y se puede presentar algún posicionamiento del vehículo automatizado.El vehículo puede ser cargado y liberado. Se puede presentar detección de fallas.
Patent CO-6670523-A2 (CO)
Title: Anticuerpos específicos para proteína de activación fibroblástica (fap), polinucleotidos que codifican dichos anticuerpos, y vectores y células huesped que comprenden dichos nucleótidos
Inventor: BACAC MARINA
IPC: C07K16/40
Filed: 2013-01-17
Abstract: La invención proporciona anticuerpos contra la proteína de activación fibroblástica (FAP) y métodos de utilización de los mismos.
Patent DD-156915-A2 (DD)
Title: Verfahren zur herstellung von mit ungesaettigten oelen bzw.fettsaeuren modifizierten resolen
Inventor: HITZER H
IPC: C08G8/28
Filed: 1977-04-13
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung von mit ungesaettigten Oelen bzw. Fettsaeuren modifizierten Resolen, die vorzugsweise zur Herstellung von elektrisch und mechanisch hochwertigen Schichtpressstoffen fuer die Elektroindustrie verwendet werden. Nach Hauptpatent WP145020 erfolgt die Herstellung dieser Resole durch eine Stufenkondensation. Diese Verfahrensweise erfordert die Durchfuehrung einer Vakuumdestillation und eine staendige Messung des Kondensationsgrades, was zu einer Unterbrechung des Produktionsablaufes fuehrt. Erfindungsgemaess werden alle Rohstoffe, d.h. phenolische Rohstoffe, Formaldehyd, Ammoniak, Alkali oder Saeuren, niedrig- oder hochsiedende Alkohole und ungesaettigte Oele bzw. Fettsaeuren auf 100 Grad C erhitzt, die dann 30-60 min miteinander reagieren.
Patent DD-208641-A2 (DD)
Title: Vorrichtung zur erhoehung der gleislagestabilitaet in bestehenden gleisen
Inventor: WIEGAND GERHARD
IPC: E01B27/20
Filed: 1982-06-22
Abstract: Werkzeug einer Unterschneidmaschine zur Schotterbearbeitung in bestehenden Gleisen ergaenzt das Hauptpatent DD-WP 160118 durch Anordnung einer mit einer auswechselbaren, gezaehnten Verschleissleiste ausgestatteten Rinnenbodenabstufung, die bewirkt, dass der Eindringwiderstand des Schwingfoerderrinnenbodens in den Schotter verringert wird, der aufgebrochene Schotter stufenweise zur Schwingfoerderrinnenbodenoberflaeche geworfen wird und eine Verstaerkung der Unterseite des Schwingfoerderrinnenbodens die fuer den reaktionsfreien Mittelteil der Schwelle erforderliche Hohllage der Schwelle ermoeglicht.
Patent DD-212973-A2 (DD)
Title: Verfahren zur aufbereitung von braunkohlenteeren und hochsiedenden teeroelen
Inventor: LANDGRAF DIETER
IPC: C10C1/18
Filed: 1983-01-13
Abstract: Die Erfindung betrifft eine weitere Vervollkommnung des im WP 200276 angemeldeten Verfahrens zur Aufbereitung von Braunkohlenteeren und hochsiedenden Teeroelen. Das Ziel, das Verfahren so zu gestalten, dass eine vielseitige Verwendungsmoeglichkeit des Braunkohlenschwelteeres erhalten bleibt u. die Aufgabe geeignete Loesungsmittel zu finden wird geloest, indem als Kreosotpechloeser Phenoloele oder deren Destillationsrueckstaende aus kohlestaemmigen Teeren, Pechen, Oelen oder Prozesswaessern eingesetzt werden.
Patent EP-1035496-A2 (EP)
Inventor: OKI HAJIME
IPC: G06K17/00
Filed: 2000-03-08
Abstract: An IC card reader comprising an contact and a rotating
member. The contact is for coming into contact with an IC
contact terminal of a card. The rotating member is rotated by
the insertion of the card. The rotating member starts to rotate
as the card presses a portion of the rotating member, and the
portion of the rotating member presses the card on a rear surface
thereof when the rotating member rotates.
Patent EP-1061537-A2 (EP)
Inventor: SHIRASHIGE MICHIHIRO
IPC: H01G9/15
Filed: 2000-06-14
Abstract: A terminal frame including plural pairs of terminal sections arranged in
rows and columns is prepared. Each pair includes a flat anode terminal
section and a flat cathode terminal section disposed in the same plane with
their tip ends being spaced from and facing each other. Plural capacitor
elements are prepared. Each capacitor element has a cathode layer on
substantially entire outer surface thereof, and a tantalum lead. The capacitor
elements are placed on the frame. The tantalum lead of each capacitor
element is coupled to one major surface of the anode terminal section of one
pair of terminal sections, with the cathode layer of that capacitor element
coupled to one major surface of the cathode terminal section of the same pair.
The frame with the capacitor elements mounted thereon are coated with resin in
such a manner that all of the capacitor elements are encapsulated in the resin,
while at least a portion of the opposite major surface of each anode terminal
section and at least a portion of the opposite major surface of each cathode
terminal section are left exposed. After that, the frame and the resin
encapsulation are cut to separate the capacitor elements with the anode and
cathode terminal sections into individual chip capacitors.
Patent EP-1070642-A2 (EP)
Inventor: RUDOLF MANFRED DR
IPC: B60S1/48
Filed: 2000-07-14
Abstract: The device has a sealing element(5) with a larger volume than the communicating receiving opening(41) of the connecting element(40). The sealing element is made of an elastically deformable material and has at least one through-hole(51) with a larger diameter than the heating conductor and by at least one cap element(6) detachably connected to the connecting element is fixed to it. The sealing element has larger axial and radial dimensions than the communicating receiving opening of the connecting element.
Patent EP-1074420-A2 (EP)
Inventor: MEYER DIRK
IPC: G05G1/30
Filed: 2000-08-03
Abstract: The accelerator pedal module has a pedal plate (10) on a bearing bracket (11), at least one spring (13,14) exerting a restoring force on the plate, a friction element (19) for producing hysteresis and a wedge-shaped surface (21) opposite the friction surface (17). The friction element is longitudinally movably mounted in the bearing bracket with one friction surface on one end and a pressure surface on the other. The other friction surface (18) is mounted on a protruding friction segment (20) on the bottom of the pedal plate.
Patent EP-1083469-A2 (EP)
Inventor: KAKINO YOSHIAKI
IPC: G05B19/416
Filed: 2000-09-07
Abstract: A control method for an NC machine tool is
provided which ensures a high precision of the
contouring control, and allows for extension of the
drill life, and reduction in machining time. The
control method comprises: generating an operation
command signal on the basis of the machining program and
a time constant; generating a velocity command signal
by multiplying a deviation of a present position signal
fed back from the feed drive system (106) from the
generated operation command signal by a position loop
gain; generating an electric current command signal by
multiplying a deviation of a present velocity signal fed
back from the feed drive system (106) from the generated
velocity command signal by a velocity loop gain; and
controlling a drive motor of the feed drive system (106)
on the basis of the generated electric current command
signal for driving thereof, wherein a machining mode is
determined from the machining program and, if the
machining mode is a drilling mode, at least one of the
operation command signal, the velocity command signal
and the electric current command signal is modified when
the feed drive system (106) is driven to be retracted
opposite to a drilling feed direction.
Patent EP-1094002-A2 (EP)
Inventor: JOERCK HARTMUT
IPC: B64G1/24
Filed: 2000-10-05
Abstract: The control arrangement has at least one reference target sensor connected to devices for selecting reference targets and for determining their positions, a device for estimating model parameters and external disturbances, reference target catalogue and reference trajectory memories, a controller connected to satellite position control elements and a filter. The control arrangement has at least one reference target, e.g. star, sensor connected to a device for selecting reference targets and a device for determining their positions, a device for estimating model parameters and external disturbances, a reference target catalogue memory, a reference trajectory memory, a controller connected to control elements for satellite position control and a filter connected to the position determination device, the model parameter estimation device, the first memory and the controller. Independent claims are also included for the following: a control method for satellites.
Patent EP-1103226-A2 (EP)
Inventor: SCHAEFER BERND
IPC: A61B17/70
Filed: 2000-10-12
Abstract: The cross-link (10) has a rod-shaped section (12) for fixing it and a clamping section for attaching the fixture rod which is contained in a opening (26) in the clamping section. The opening has a slot (28) opening towards the edge. The clamping section is in two parts with a clamping cover (20) which has a U-shaped bracket gripping round the rod-shaped section.
Patent EP-1139327-A2 (EP)
Inventor: INOUE MITSUO
IPC: G02F1/1368
Filed: 2000-12-22
Abstract: In a color liquid crystal display device, two capacitors (18, 19) are
both connected in parallel between a pixel signal line (4) and an electrode
(2a) of a liquid cell (2), or one of the capacitors is connected therebetween,
or none of the capacitors are connected therebetween, in order to selectively
set a potential (V2) of the electrode (2a) of the liquid crystal cell (2) in four
steps. Therefore, gradation display in four steps can be performed without
a digital-to-analog conversion circuit, so that the cost of the device can be
reduced.
Patent EP-1065639-A2 (EP)
Inventor: ADDISON IAN
IPC: G06Q20/18
Filed: 2000-05-18
Abstract: A self-service terminal (SST) fascia (12) comprises a
touch-sensitive display (14) capable of displaying a
selection of images and at least one further user-interfacing
element, such as a card reader slot (18) or a
receipt printer slot (22), incorporated within the display
(14) so that the display (14) surrounds the user-interfacing
elements.
Patent EP-1095680-A2 (EP)
Inventor: MATSUURA MASAYA
IPC: A63F13/10
Filed: 2000-10-13
Abstract: An image processing apparatus for displaying novel
three-dimensional line drawing images on a display screen is
disclosed. A character object line drawing image (401Ih) is
displayed on a virtual road object line drawing image
(402Ih) having obstacle object line drawing images (411Ib,
412Ib, 413Ib, 414Ib) therein. By imparting vibrations to
the obstacle object line drawing images (411Ib, 412Ib, 413Ib,
414Ib), virtual road object line drawing image (402Ih), and
character object line drawing image (401Ih), novel line
drawing images can be displayed.
Patent EP-1188076-A2 (EP)
Inventor: MENEZES EDGAR V
IPC: G02B3/04
Filed: 2000-05-02
Abstract: The present invention provides multifocal ophthalmic lenses. In particular, the invention provides lenses in which channel power progression modification is achieved without a significant increase in unwanted astigmatism.
Patent EP-1196615-A2 (EP)
Inventor: VARIN LUC
IPC: C12N15/54
Filed: 2000-07-06
Abstract: The present invention relates to methods, compositions and genetic sequences for modulating flowering in plants and to plants genetically modified to flower early and to plants genetically modified to flower tardily. More particularly the present invention provides among others a genetic sequence encoding for a hydroxyjasmonic acid sulfotransferase and methods for producing transgenic plants using such a sequence.
Patent EP-1212321-A2 (EP)
Inventor: GRINTER TREVOR JOHN
IPC: C07D207/00
Filed: 2000-09-01
Abstract: Chemical intermediates of formula (I) and their preparation which are of use in the production of naphthyridine carboxylic acid derivatives having antibacterial activity.
Patent EP-1181401-A2 (EP)
Inventor: CARTER CALVIN H JR
IPC: H01L29/778
Filed: 2000-05-17
Abstract: A semi-insulating bulk single crystal of silicon carbide is disclosed that has a resistivity of at least 5000 OMEGA-cm at room temperature and a concentration of deep level trapping elements that is below the amounts that will affect the resistivity of the crystal, preferably below detectable levels. A method of forming the crystal is also disclosed, along with some resulting devices that take advantage of the microwave frequency capabilities of devices formed using substrates according to the invention.
Patent EP-1410609-A2 (EP)
Inventor: SPRINGER ARTHUR L
IPC: H04M17/00
Filed: 2000-12-18
Abstract: L'invention concerne un procédé d'interception d'appels (CIP) concernant des appels internationaux effectués par carte d'appel d'un pays de départ (102), vers un pays de destination où le nombre de fraudes est élevé. Lorsqu'un appel placé au moyen d'une carte d'appel aboutit à un lieu où le nombre de fraudes est élevé, il est filtré dans un premier temps relativement à une base de données (120) pour déterminer si le lieu de destination est un pays où le nombre de fraudes est élevé. Indépendamment du processus de filtrage, l'appel est acheminé vers un opérateur de premier niveau qui vérifie les informations relatives au compte de facturation (130) de l'appelant afin de déterminer si ce dernier est un usager autorisé. Cette vérification s'effectue sur la base du nom commercial, de l'adresse, du code postal et du numéro de téléphone du client. Une fois l'étape de vérification franchie avec succès, le procédé CIP affranchit automatiquement la carte d'appel de toute procédure d'interception ultérieure (135). Si l'appelant échoue à l'examen de vérification, le procédé CIP place automatiquement la carte d'appel dans un mode appelé 'mode de verrouillage de la carte' (145).
Patent EP-1237525-A2 (EP)
Inventor: LEHMANN THOMAS
IPC: A61K6/893
Filed: 2000-12-15
Abstract: The invention relates to compositions containing: (a) 14 to 55 wt.-% fillers, (b) 3 to 35 wt.-% of at least one mono- or polyethylenically unsaturated compound which is not a urethane (meth)acrylate, (c) 0.1 to 5 wt.-% of at least one initiator system which is capable of starting a radical reaction, (d) 1 to 40 wt.-% plasticizers, (e) 0 to 10 wt.-% auxiliaries such as dyes, pigments, stabilizers, solvents, rheological additives such as flow-improvers and/or retarders, and (f) 30 to 81.9 wt.-% of at least two urethane (meth)acrylates with different molecular weights, these being present in a molecular weight ratio of 1.5:1 to 50:1.
Patent EP-1120796-A2 (EP)
Inventor: GOTOH MASASHI
IPC: H03H7/52
Filed: 2001-01-25
Abstract: In the case where an electrode conductor is formed on a
principal plane of an element 10, a method including a step of
forming an electrode conductor section 13 composed of a conductor
pattern having a photosensitive conductive paste exposed and
developed on the principal plane, and a step of forming an
electrode conductor section 11 of a non-photosensitive
conductive paste, wherein both electrode conductor sections 11,
13 are disposed on the surface of the element 10 so as to be
at least partly contacted or overlapped with each other.
Patent EP-1096424-A2 (EP)
Inventor: WONG PING WAH
IPC: G06T1/00
Filed: 1996-05-10
Abstract: A technique, referred to as area-based interpolation, performs image
interpolation. The system determines a curve by the pixel value at a location by
taking the integral of a curve over a small area, where the size of the area is
determined by the sampling size of a sampling cell. When the image is
resampled with respect to a sampling cell that has a finer spacing, the system
integrates the polynomial using a finer integration area. 
     The relation between the reintegrated, resampled high resolution
image and the low resolution image is a function of an up-sampler, followed by
a linear filter. The coefficients of the filter are independent of the data, but are
dependent on the family of curves used. If the system models by, for example,
a third degree or fourth degree polynomial everywhere in the image, then that
model determines the number of coefficients that are in the filter. Once the up-sampling
factor and degree of the polynomial are determined, the filter
coefficients are fixed, and can be calculated by solving a set of linear equations.
It is not necessary to determine these values on an image-by-image basis. The
system calculates the filter once and the consistency constraint is then satisfied
for all image scaling.
Patent EP-1110945-A2 (EP)
IPC: C09B35/14
Filed: 1996-05-01
Abstract: Amyloid binding compounds which are derivatives of Chrysamine G,
pharmaceutical compositions containing, and methods using such compounds to
identify Alzheimer's brain  in vivo  and to diagnose other pathological conditions
characterized by amyloidosis, such as Down's Syndrome are described.
Pharmaceutical compositions containing Chrysamine G and derivatives thereof
and methods using such compositions to prevent cell degeneration and amyloid-induced
toxicity in amyloidosis associated conditions are also described.
Methods using Chrysamine G derivatives to stain or detect amyloid deposits in
biopsy or post-mortem tissue are also described. Methods using Chrysamine G
derivatives to quantify amyloid deposits in homogenates of biopsy and post-mortem
tissue are also described.
Patent EP-1127782-A2 (EP)
Inventor: AUER MARCUS
IPC: B62M25/04
Filed: 2001-02-22
Abstract: Die Erfindung betrifft eine Gangwahleinrichtung (1) für ein Schaltgetriebe, insbesondere für einen Fahrradantrieb, mit einer Steuereinrichtung (5), die über ein Kraftübertragungselement auf das Schaltgetriebe wirkt, einer Betätigungseinrichtung mit einem rotatorisch bewegbaren Betätigungselement zur manuellen Betätigung der Steuereinrichtung (5), und einer Anzeigeeinrichtung (3) mit einem entlang einem Kreisbogen bewegbaren Indikatorelement (4) zur Anzeige des mittels der Betätigungseinrichtung gewählten Schaltzustands. Hierbei werden Winkelbewegungen von der Betätigungseinrichtung oder der Steuereinrichtung (5) über eine Übersetzungsvorrichtung auf die Anzeigeeinrichtung (3) so übertragen, dass der jeweils vom Indikatorelement (4) der Anzeigeeinrichtung (3) durchlaufene Kreisbogen kleiner ist als der gleichzeitig vom Betätigungselement der Betätigungseinrichtung durchlaufene Kreisbogen. Dies führt zu einer verbesserten Ablesbarkeit der Anzeigeeinrichtung (3) und zu einer verbesserten Ergonomie der Gangwahleinrichtung (1). <IMAGE>
Patent EP-1133980-A2 (EP)
Inventor: HEIDENFELDER THOMAS DR
IPC: A61K47/24
Filed: 2001-03-01
Abstract: A photostable ultraviolet (UV) filter for protecting human skin or hair against sunlight contains as UV-A absorbing components a combination of a hydroxybenzophenone (I), optionally together with a 4,4-diaryl-butadiene (II); and other UV protectant(s) i.e. dibenzoylmethane, triazine, benzotriazole, benzimidazole, tetrahydroxybenzophenone and/or organosiloxane-benzal malonate derivatives. Use of a light-protectant combination of a UV-A absorber and further UV-A and/or UV-B absorbers is claimed as a photostable UV-filter in cosmetic or pharmaceutical preparations for protecting human skin or hair against sunlight, optionally used together with other conventional light protectants. First UV light absorber is a hydroxybenzophenone of formula (I), optionally together with a 4,4-diaryl-butadiene of formula (II); and other UV protectants including 4-(R6)-4'-(R7)-dibenzoylmethane, 1,3,5-triazine derivatives of formula (III), 2,4,6-triphenyl-1,3,5-triazines, in which the phenyl rings are bonded with at least one o-hydroxy group and at least one p-(1-20C) alkoxy group, 2,2'-dihydroxy-3,3'-bis-(1,2,3-benzotriazol-2-yl)-5,5'-bis-(1,1,3,3-te tramethylbutyl)-diphenylmethane, 1,4-bis-(5,6-disulfo-benzimidazol-2-yl)-benzene or its salts, 2-(2-hydroxy-3-(2-methyl-4,4-bis-(trimethylsilyloxy)-4-silapentyl)-5-m ethyl)-1,2,3-benzotriazole, 2,2',4,4'-tetrahydroxybenzophenone and/or siloxanes of formula (IV). R1, R2 = H, 1-20C alkyl, 3-10C cycloalkyl or 3-10C cycloalkenyl; or NR1R2 = 5-6 membered ring; R3 = 1-20C alkyl; R4, R5 = H, 1-20C alkyl, 3-10C cycloalkyl or 3-10C cycloalkenyl; R6 = 1-12C alkyl; R7 = H, 1-12C alkyl or 1-12C alkoxy; R8-R10 = optionally substituted 1-20C alkyl, 5-10C aryl, 5-10C heteroaryl or -Sp-Sil; Sp = spacer; Sil = silane, oligosilane or polysiloxane residue; X = O or NR11; R11 = H or optionally substituted 1-20C alkyl, 5-10C aryl, 5-10C heteroaryl; V = 3-(4-(2,2-bis-(ethoxycarbonyl)-vinyl)-phenoxy)-prop-1-en-1-yl or 3-(4-(2,2-bis-(ethoxycarbonyl)-vinyl)-phenoxy)-prop-1-en-2-yl; V' = V or Me; t = up to 100; u = up to 20; provided that u = 0 if V' = V or u = 1-20 if V' = Me. An Independent claim is also included for cosmetic or pharmaceutical preparations for protecting human epidermis or hair against UV light in the 280-400 nm range, comprising the UV absorbing combination, a carrier and optionally other conventional light protectants.