baber/WOPTO huggingface dataset:
Patent NZ-244102-A (NZ)
Title: Peptides inducing cytotoxic t lymphocyte responses against hbv antigen and their use
Inventor: CHISARI FRANCIS V
IPC: A61K38/00
Filed: 1992-08-26
Abstract: Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV nucleocapsid, envelop, polymerase and the transcriptional transactivator X protein, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens. Pharmaceutical compositions and hepatitis B vaccines which comprise the peptides and physiologically acceptable carriers can be employed in conjunction with other HBV vaccinss to provide more effective immunity against the disease. Methods for identifying individuals who are particularly susceptible to developing chronic HBV infection and who can be targeted for treatment by the CTL peptides are also provided.
Patent NZ-250760-A (NZ)
Title: Fungicidal composition comprising a polyene antifungal agent, an acidic antifungal compound or salt thereof and an acid or salt thereof
Inventor: VAN RIJN FERDINAND THEODORUS J
IPC: A01N37/04
Filed: 1994-01-26
Abstract: An antifungal composition is disclosed which comprises an antifungal agent of the polyene type, an acidific antifungal compound and an additional organic acid or its alkali or earth alkali salt. The use of this composition to treat food and agricultural products is disclosed.
Patent NZ-252528-A (NZ)
Title: Method and apparatus for automatic chemical analysis of samples for multiple analytes
Inventor: CHOPERENA ALFREDO
IPC: G01N35/04
Filed: 1993-05-04
Abstract: This automated chemical analyzer comprising:a) an incubation station (50) comprising an elongated, movable track adapted to carry a plurality of reaction vessels (52) along an incubation path (58);b) a wash station (100) including a movable track adapted to carry a plurality of reaction vessels along a wash-cycle path having spaced-apart first and second ends; andc) a read station (130) including signal detection means positioned adjacent the second end of the wash-cycle path, the read station defining a read path ;d) a first transfer station means (80) positioned adjacent the first end of the wash-cycle path for transferring a vessel from the incubation path (58) to the wash-cycle path ; ande) a second transfer station means positioned adjacent the second end of the wash-cycle path and a first end of the read path for selectively transferring a vessel from the wash-cycle path to either the incubation path or the read path.
Patent NZ-268470-A (NZ)
Title: Production of a peptide containing the egf-like domain of human urokinase-type plasminogen activation (hupa)
Inventor: ROSENBERG STEVEN
IPC: C12N15/58
Filed: 1994-05-19
Abstract: Unfucosylated huPAR polypeptides that contains huPA1-48 (SEQ ID NQ:22) are provided. These polypeptides are useful for treating diseases wherein antagonism of huPAR is therapeutically beneficial.
Patent NZ-282616-A (NZ)
Title: Improving pulp brightness by rapid displacement heating and alkali charge pretreatment
Inventor: SHIN NAM HEE
IPC: D21C9/10
Filed: 1995-03-02
Abstract: A method for improving pulp brightness utilizes a combination of a distributed total white liquor charge during the warm fill, hot fill and cooking stages of a batch cooking process and low cooking temperatures during the cooking stage. The high total white liquor charge ranges between 15 % AA  &tilde&  35 % AA, while the cooking temperatures range between 150  &tilde&  168  DEG C._________________________
Patent NZ-289115-A (NZ)
Title: Laundry compositions with cellulase and pectinase enzymes suitable for degrading cell walls of vegetable origin
Inventor: CUPERUS ROULCK ANNEKE
IPC: D06L4/40
Filed: 1995-06-19
Abstract: PCT No. PCT/EP95/02380 Sec. 371 Date Jan. 30, 1997 Sec. 102(e) Date Jan. 30, 1997 PCT Filed Jun. 19, 1995 PCT Pub. No. WO95/35362 PCT Pub. Date Dec. 28, 1995This invention relates to a laundry detergent composition as well as a method of laundrying fabric or soiled garments in which the composition requires a surfactant, a pectinase enzyme, a specific hemicellulase enzyme or enzymes, a cellulase enzyme, and additional component which includes bleaching agents, builders, an amylase enzyme and/or a protease enzyme.
Patent NZ-293763-A (NZ)
Title: Method of purifying an anti-inflammatory factor from skimmed milk
Inventor: BECK LEE R
IPC: A61K35/54
Filed: 1995-09-08
Abstract: The invention relates to an anti-inflammatory factor isolated from milk, methods of purifying the anti-inflammatory factor resulting in substantially or highly purified preparations and to methods for using this factor to remove adhered neutrophils from endothelial cells, to prevent the emigration of cells from the vasculature and to suppress the response of lymphocytes to foreign antigens.
Patent NZ-303355-A (NZ)
Title: Anti-cross contamination valve with three ports and barriers to prevent the first port coming into contact with the second port
Inventor: WILSON ROLAND B
IPC: A61M39/22
Filed: 1996-01-18
Abstract: An anti-cross contamination valve for use in medical fluid delivery systems comprises a valve housing having a first port, a second port, and a third port that open into a hollow interior. A valve body is rotatably mounted within the hollow interior and has at least one fluid passageway therethrough. A knob is attached to the valve body and extends outside of the valve housing. The at least one passageway includes a first fluid passageway that opens the first port to the third port when the valve body is rotated to a first position with respect to the valve housing. The second port is closed when the valve is in its first position. The at least one passageway also includes a second fluid passageway that opens the second port to the third port when the valve body is rotated to a second position with respect to the valve housing. The first port is closed when the valve is in its second position. In order to prevent the possibility of cross contamination, the valve also includes stop barriers and/or a special passageway/port geometry that prevents the possibility of the first port coming into fluid communication with the second port, or vice versa.
Patent NZ-311535-A (NZ)
Title: A method for the control of antibiotic-resistant gram positive bacteria and treatment of infection
Inventor: BLACKBURN PETER
IPC: A61K38/16
Filed: 1996-06-21
Abstract: Described is the use of a lanthocin antimicrobial selected from the group consisting of nisin, subtilin, epidermin, gallidermin and pep 5, in the manufacture of a medicament for the treatment of an antibiotic-resistant isolate of a genus selected from Staphylococcus, Streptococcus and Enterococcus. Also described is a method of killing the abovementioned bacteria in a non-human animal, wherein the method comprises administering a lanothocin selected from nisin, subtilin, epidermin, gallidermin and pep 5 to said non-human animal.
Patent NZ-332667-A (NZ)
Title: Beverage dispensing head, contains coolant lines
Inventor: SPILLMAN ROBERT A
IPC: B67D1/08
Filed: 1998-11-04
Abstract: In a beverage dispenser head, of the type where beverage is dispensed through a flexible hose, the hose contains coolant lines 21b, 21c.  The coolant lines may circulate a refrigerant such as glycol, or may circulate cooled water, which may also be mixed with the beverage being dispensed, for example in a post-mix beverage dispenser.
Patent NZ-333803-A (NZ)
Title: Container for holding sterilized elements, open end of bag encapsulated in sealing material and located in a groove of a transfer port
Inventor: NORTON PAUL H
IPC: A61B19/02
Filed: 1997-07-15
Abstract: container 10, for holding elements 12 to be sterilized prior to introduction into an isolation system, is claimed .  The container includes a flexible bag 14 having a first end 14a defining a first opening for removing the elements. The bag includes a transfer port 26 that is engageable with the isolation system for transferring the sterilized elements into the isolation system.  The transfer port has a bore 30 extending through it.  The exterior surface 28 of the bore has a clamp receiving area 32 and a groove 34. The first end of the bag is located in the groove.  A clamp 38 is located around the flexible bag near the first end. A portion of the flexible bag is clamped between the clamp and the clamp receiving area on the transfer port.  A sealing material 44 is located in the groove and encapsulates the first end of the flexible bag to form a hermetical seal.
Patent NZ-335212-A (NZ)
Title: Process for the preparation of 14- alkoxyindolomorphinans and 14-alkoxybenzofuranomorphinans
Inventor: SCHMIDHAMMER HELMUT
IPC: C07D491/18
Filed: 1996-11-19
Abstract: A process for preparing a compound of the formula (I) comprises: ia) reacting naloxone of formula (II), naltrexone of formula (III) or oxymorphone of formula (IIIa) with phenylhydrazine hydrochloride in the presence of acid producing naloxindole of formula (NLI), naltrindole of formula (NTI) or oxymorphindole of formula (OMI) or ib) naloxone of formula (II), naltrexone of formula (III) or oxymorphone of formula (IIIa) is reacted with O-phenyl- hydroxyl amine hydrochloride in the presence of acid, producing the benzofurane derivatives of formula (NLB), naltriben of formula (NTB) or OMB of the formula (OMB); ii) protecting the 3-hydroxy group present in the products of step ia) or ib) by alkylation with benzyl bromide, methoxymethyl bromide, ethoxymethyl bromide, trityl chloride, or a silylating agent, in the presence of a solvent and a base, producing a compound of the formula (IV) iii) treating a compound of the formula (IV) with dialkyl sulphates, alkyl halides, alkenyl halides, aralkyl halides, arylalkenyl halides, alkanoyl halides, or arylalkanoyl halides in a solvent such as N,N dimethyl formamide or tetrahydrofurane, using a base, producing a compound of the formula (V) or iv) optionally hydrolyzing in diluted acids a compound of formula (V) optionally in the presence of a solvent, producing a compound of the formula (VI) and v) alkylating or acylating the compound of the formula (VI) to produce a compound of the formula (I) wherein: R1 is allyl, cyclopropylmethyl or methyl; R2 is alkoxy, alkenyloxy, arylalkyloxy, arylalkenyloxy alkanoyloxy or arylalkanoyloxy; R3 is hydroxy, alkoxy, arylalkyloxy, alkenyloxy, alkanoyloxy, arylalkanoyloxy or alkyloxyalkoxy; X is O, NH or NR4 and R4 is alkoxy, alkenyloxy, arylalkyloxy, arylalkenyloxy, alkanoyloxy or arylalkanoyloxy provided that when R1 is cyclopropylmethyl and R2 is methoxymethyl X is not O or N-methoxymethyl. In formula (IV) R2 is benzyl, methoxymethyl, ethoxymethyl, trityl or silyl; and X is NH, O, N-benzyl, N-methoxymethyl, N-ethoxymethyl, N-trityl or N-silyl. In formula (V) R2 is benzyl, methoxymethyl, ethoxymethyl, trityl or silyl and X is NH, O, N-benzyl, N-methoxymethyl, N-ethoxymethyl, N-trityl or N-silyl. In formula (VI) X is NH, O or N-benzyl.
Patent NZ-337121-A (NZ)
Title: Pyrazine compounds as good anti-convulsants for the treatment of CNS diseases such as epilepsy
Inventor: COX BRIAN
IPC: C07D241/26
Filed: 1998-02-26
Abstract: Pyrazine compounds of the Formula (I) useful in the treatment of central nervous system (CNS) diseases and disorders and to their pharmaceutically acceptable derivatives, pharmaceutical compositions containing them, to their use in the treatment of such disorders and to methods of preparing them. Wherein; R1 is selected from the group consisting of phenyl substituted by one or more halogen atoms, naphthyl and naphthyl substituted by one or more halogen atoms; R2 is selected from the group consisting of -NH2 and -NHC(=O)Ra; R3 is selected from the group consisting of -NRbRc, -NHC(=O)Ra and hydrogen; R4 is selected from the group consisting of hydrogen, -C1-4alkyl, -C1-4alkyl substituted by one or more halogen atoms, -CN, -CH2OH, -CH2ORd and -CH2S(O)xRd; wherein Ra represents C1-4alkyl or C3-7cycloalkyl, and Rb and Rc, which may be the same or different, are selected from hydrogen and C1-4alkyl, or together with the nitrogen atom to which they are attached, form a 6-membered nitrogen containing heterocycle, which heterocycle can be further substituted with one or more C1-4alkyl; Rd is selected from C1-4alkyl or C1-4alkyl substituted by one or more halogen atoms; x is an integer zero, one or two; with the proviso that R1 does not represent Formula (II); when R2 is -NH2, and both R3 and R4 are hydrogen.
Patent NZ-503356-A (NZ)
Title: Leak testing system for pipes
Inventor: ASHWORTH ROGER PHILIP
IPC: F16L55/44
Filed: 1998-08-20
Abstract: A leak testing system for pipes includes: i) means for providing a temporary seal at a first location in a pipe; ii) means for providing a substantially equal pressure between the first location and an adjacent test location in the pipe to prevent fluid passage between the first location and the test location; iii) means for determining any pressure decay at the test location indicative of pipe leakage; and iv) means for measuring and adjusting the pressure in the first location to track the pressure in the test location so as to maintain the substantially equal pressure between the first and test locations during testing. Also described is a method for testing leaks in pipes comprising: i) providing a temporary seal at a first location in a pipe; ii) providing a substantially equal pressure between the first location and an adjacent test location in the pipe to prevent fluid passage between the first location and the test location; iii) determining any pressure decay at the test location indicative of pipe leakage; and iv) measuring and adjusting the pressure in the first location to track the pressure in the test location so as to maintain the substantially equal pressure between the first and test locations during testing.
Patent NZ-503513-A (NZ)
Title: Sustained-release liposomal anesthetic compositions
Inventor: KIM SINIL
IPC: A61P23/02
Filed: 1998-09-18
Abstract: A pharmaceutical composition comprises a) a multivesicular liposome comprising at least one type of amphipathic lipid and at least one type of neutral lipid and b) an aqueous phase comprising polyhydroxy carboxylate salts and di- or tri-protic mineral salts of amide-type anesthetics, wherein the aqueous phase is encapsulated within the multivesicular liposome. Also described is a process for preparing a multivesicular liposome-encapsulated composition and a method for increasing drug loading in multivesicular liposomes by converting an amide-type anesthetic into a binary salt mixture wherein the two counterions are derived from polyhydroxy carboxylic acid and a di- or tri-protic mineral acid. The pharmaceutical composition can be used in the manufacture of an injectable medicament for locally anesthetizing a subject wherein the medicament is prepared for subcutaneous, intracutaneous or a nerve block injection.
Patent NZ-506020-A (NZ)
Title: Use of pharmaceutical combinations containing tramadol and an antiemetic
Inventor: RABER MARC
IPC: A61K31/415
Filed: 1999-02-17
Abstract: A combination of a prokinetically active antiemetic agent and tramadol ((1RS,2RS)-2-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexanol) is used for treating migraine, migraine-type headaches or pain accompanied by nausea, vomiting or delayed gastric emptying.   Preferred antiemetics are metoclopramide, domperidone or 5-HT3 antagonists.
Patent NZ-518184-A (NZ)
Title: Heated wheel for application of heat-activated or pressure sensitive precoated adhesive tape or string
Inventor: BRADSHAW DENNIS A
IPC: B29C65/00
Filed: 2000-12-01
Abstract: A heated wheel for applying heat activated tape to a substrate. The wheel includes a rim with a longitudinal axis and a cylindrical outer surface for engaging heat activated tape. An electrical heater is supported within, and in fixed relation to, the rim. The wheel also includes a solid body of polymer and a bearing.
Patent NZ-519774-A (NZ)
Title: Pharmaceutical compositions comprising the HMG CoA reductase inhibitorHMG CoA reductase inhibitor (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid with an inorganic salt
Inventor: CREEKMORE JOSEPH RICHARD
IPC: A61K33/30
Filed: 2000-08-04
Abstract: Described are pharmaceutical compositions comprising (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R, 5S)-3,5-dihydroxyhept-6-enoic acid, and an inorganic salt in which the cation is multivalent, provided the inorganic salt is not synthetic hydrotalcite or a tribasic phosphate salt.
Patent NZ-521026-A (NZ)
Title: Production of mammals which produce progeny of a single sex
Inventor: ROBL JAMES M
IPC: A01K67/027
Filed: 2001-02-26
Abstract: A method for producing a non-human mammal which has an altered tendency to produce progeny of a particular sex, comprising introducing a nucleic acid construct into at least one sex chromosome of the germ line of said mammal, wherein said nucleic acid construct encodes a transgene which is expressed post-meiotically in developing spermatids, and wherein expression of said transgene alters the fertility of sperm resulting from said developing spermatids, such that said mammal has an altered tendency to produce progeny of a particular sex.
Patent NZ-521408-A (NZ)
Title: Capsules
Inventor: DRAISEY ALLAN
IPC: A61K9/48
Filed: 2001-03-15
Abstract: Capsules, for example for the delivery of pharmaceuticals, are produced from two films (18) of a water-soluble polymeric material, by deforming the films to form a multiplicity of recesses, and filling the recesses with a flowable filling material. This is performed using two adjacent rotary dies (14, 15), with recesses (16) into which the films (18) are deformed. The dies (14, 15) also act as electrodes for welding the films together by dielectric welding to form filled capsules (30). The capsules (30) can readily be separated from the resulting web. The polymeric material may be gelatin, or a water-soluble cellulose derivative such as hydroxypropyl methyl cellulose, and may also contain a plasticiser.
Patent NZ-521474-A (NZ)
Title: Process for forming an amide bond
Inventor: ROSSLER ARMIN
IPC: C07D401/14
Filed: 2001-03-08
Abstract: A process for forming an amide bond, comprising reacting a carboxylic acid with an amine carboxylate salt, in the presence of an inorganic base, wherein the salt product of the inorganic base cation and the carboxylate anion has a solubility in water or a polar organic solvent less than or equal to about 5 part/100 parts water or polar organic solvent, at a pH in the range of about 5-10.
Patent NZ-526637-A (NZ)
Title: A fastener driver with a fastener supply that includers a detector to sense the length of the fastener
Inventor: SHKOLNIKOV YURY
IPC: B25C7/00
Filed: 2003-06-23
Abstract: A tool for driving fasteners into a workpiece, including a housing, a nosepiece at least partially defining a channel through which fasteners are expelled, and a fastener supply attachable to the tool and supplying the fasteners to the channel, comprising a sensor held by the housing, and a detector within the fastener supply configured to sense the length of the fasteners and communicates the length to the sensor. Also described is an adaptation kit for adapting a tool, comprising an interchangeable workpiece contact element, and a fastener supply device as defined above.
Patent NZ-535355-A (NZ)
Title: Antibiotic conjugates
Inventor: BURNET MICHAEL
IPC: C07D413/14
Filed: 2003-02-14
Abstract: Disclosed is an antibiotic conjugate of formula (I) wherein the substituents are as described and there are 1-8 antibiotic therapeutic agents in the molecule. The conjugates described are particularly useful for delivering antibiotic therapeutic agents to a cell.
Patent NZ-541305-A (NZ)
Title: A net horse-cover used as a fixing device for an urine collective device placed on a horse
Inventor: FRINK MARTIN
IPC: A01K23/00
Filed: 2003-12-18
Abstract: Disclosed is a net horse-cover used as an easily used fixing device for a urine collecting device smoothly placed on a horse in such a way that it is easily replaceable. The net horse-cover used as a fixing device consists of a net (1) which covers the major part of the horse body laterally extending to the lower torso line and is closed or can be closed on the horse breast (2). Said net horse-cover is mainly used for a flexibly suspended urine collecting device (not shown) which makes it possible to obtain a natural conjugate estrogens mixture from urine of a pregnant mare. The net is a large-mesh net having holes of minimum internal width of 15 mm.
Patent NZ-541915-A (NZ)
Title: Mutations in neuronal gene sodium-channel alpha1-subunit and their polypeptides and their treatment of generalised epilepsy with febrile seizures plus
Inventor: WALLACE ROBYN HEATHER
IPC: G01N33/53
Filed: 2001-12-20
Abstract: An isolated DNA molecule encodes a mutant sodium channel alpha-1 subunit (SCN1A). The mutation results in the replacement of a valine residue at amino acid position 1353 of the alpha-1 subunit. The mutation event disrupts the functioning of an assembled sodium channel so as to produce an epilepsy phenotype. Polypeptide, antibodies, methods and uses for treating epilepsy are also described.
Patent NZ-547546-A (NZ)
Title: Material discharge apparatus and method
Inventor: SCHWASS TREVOR DOUGLAS ANTHONY
IPC: B65G65/40
Filed: 2004-12-23
Abstract: The disclosure relates to a material discharge apparatus (1), method and computer program for controlling the flow rate of flowable material being conveyed through a hopper (2), the apparatus (1) including a hopper (2) having an inlet opening (4) at the top and a discharge outlet (5) at the base of the hopper (2), and a valve means (7) configured and arranged in the hopper, the valve means (7) having a lower end portion adjacent the discharge outlet (5) forming a gap between the hopper and the valve means for material to flow therethrough, the valve means and/or the hopper being adapted to move relative to the other, in use, for controlling the rate of discharge of material through the gap. The valve means (7) is bulb- shaped and by movement relative to the hopper (2) forms a solid column of flowing material to reduce the amount of dust being dispersed into the surrounding environement.
Patent NZ-548648-A (NZ)
Title: X-ray imaging of animal carcass to determine cutting path
Inventor: SEATON MARK HAMISH
Filed: 2006-07-21
Abstract: An imaging apparatus comprise an X-ray imaging system; a carcass moving system for moving a carcass to a first position with respect to the imaging system to obtain a first X-ray image and to move the carcass to a second position, different to the first position, with respect to the imaging system to obtain a second X-ray image; and a processor for determining pseudo-3D spatial information for carcass elements based on the first and second X-ray images. A carcass segmenting system comprises the imaging apparatus described above and an automated cutting machine which receives the cutting path data from the processor and cuts a carcass in accordance with the cutting path data.
Patent NZ-554078-A (NZ)
Title: Process for producing lithium transition metal oxides
Inventor: ZOU FENG
IPC: C01G53/04
Filed: 2005-06-06
Abstract: A direct low temperature process for lithiating hydroxides and forming lithiated transition metal oxides of suitable crystallinity is disclosed, wherein, elemental transition metal powders are combined with an aqueous solution of lithium hydroxide, the aqueous slurry solution is subject to oxidation and agitation, the resultant lithium transition metal oxide is crystallized in-situ and subsequently removed from the reactor. By utilizing a relatively low processing temperature below about 150 Deg. C a desirable lithiated product is sufficiently formed. Therefore the problems associated with diffusion and atmospheric controls for heat treatment are reduced, as such a continuous rotary furnace may be employed for heat treatment rather than a batch static furnace.