baber/WOPTO huggingface dataset:
Patent CR-20220162-A (CR)
Title: Compounds and compositions for the treatment of parasitic diseases
Inventor: ZHU TINGYING
IPC: C07D519/00
Filed: 2020-10-20
Abstract: Provided herein are a compound of formula (Ia) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, solid forms, combinations of pharmacologically active agents, pharmaceutical compositions and methods of using such compounds and solid forms thereof to treat or prevent parasitic diseases, for example malaria.
Patent CR-20220647-A (CR)
Title: Process for preparing methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate
Inventor: FABER HELENE
IPC: C07D471/04
Filed: 2021-06-15
Abstract: The present application relates to a novel and efficient process with high yield for preparing methyl {4,6- diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate of the formula (I) in the crystalline form of modification I, wherein the x-ray diffractogram of the compound of the formula (I) in modification I exhibits peak maxima of the 2 theta angle at 5.9, 6.9, 22.7, in very high purity which is significantly more cost-effective than the process known from the art and can be performed in customary pilot- and production plant-equipment (stirred tank/devices for isolation).
Patent EC-SP972070-A (EC)
Title: Proceso para fabricar un polimero poroso mediante el uso de un porogeno
Inventor: MEIJS GORDON FRANCIS
IPC: B01D71/32
Filed: 1997-03-26
Abstract: La presente invención se refiere a un procedimiento para la producción de un polímero poroso que comprende los pasos de: 1) Dispersar un porógeno en una fase de componente de monómero continua en la que dicha fase de componente de monómero contínua comprende como mínimo un monómero que tiene al menos una unidad de perfluoropoliéter y donde dicho porógeno es un poli(alquilen)glicol opcionalmente sustituído, 2) polimerizar a continuación la fase de monómero continua; y 3) eliminar el porógeno del polímero poroso.
Patent EC-SP992958-A (EC)
Title: Procedimeintos para transformar escorias de la metalurgia de los metales no ferrosos
Inventor: EDLINGER ALFRED
IPC: C22B7/04
Filed: 1999-05-19
Abstract: Es un procedimiento para transformar escorias de la metalurgia de metales no ferrosos, en especial escorias siderúrgicas de Ni y Cu primarias y secundarias con la recuperación y/o el enriquecimiento de los metales no ferrosos y la formación de puzolanos sintéticos, se reducen las escorias óxidas líquidas en una primera etapa de reducción a través de un baño de metal que contiene Cu y/o Ni y, si se da el caso, Co con H2 y Co, como por ejemplo, gas de desdoblamiento. El potencial "redox" de la mezcla de Co/H2 se reduce mediante adición de un 10% a un 40% por volumen de vapor de H2O y/o CO2, para deterner la reducción de óxidos de Fe. A continuación se sigue reduciendo la escoria libre de Cu y Ni que queda a través de un baño de hierro empleándose carbono para reducir la parte de óxido de Fe para la elaboración de una escoria libre de Fe y metales no férricos.
Patent FI-20041352-A (FI)
Inventor: REHU JARI
IPC: B66F/
Filed: 2004-10-19
Abstract: A gripper and a method of handling of loads (2A), especially easily damageable goods, with a gripper provided with arms (6A, 7A) capable of clamping the load by applying a compressive force to the load wherein the compressive force applied to the load is adjusted on the basis of the slippage measured with one or several rotatable slip sensors between the load and contact pads (8A, 9A) arranged in the arms, wherein the method comprises following steps:  providing drive signals to one or several drive units arranged to rotate the rotating parts, like rollers, of the sensors,  monitoring the rotation of the rotating parts by means of the information received from the sensors, and  determining the proper operation of the sensors and/or the contact between the contact pads and the load by means of the rotation information.
Patent FR-1601604-A (FR)
Title: Automatic apparatus for continuous production of - bread from grain
IPC: A21C1/12
Filed: 1968-10-22
Granted: 1970-09-07
Abstract: Automatic apparatus for continuous production of bread from grain. Comprises (A) a section for wetting and extraction of the grain, (B) a section for separating the bran and kneading the dough (C) a section for dividing and measuring out the dough, and (D) a section for baking the dough. Section A comprises an elongated shaping vessel with a grain supply at the lower end and an outlet at the opposite end, the vessel containing a drenching zone connected to the grain supply and a liquid inlet, and an extracting zone, and organs for transporting the grain from the inlet to the outlet. Section B contains at least one pair of adjacent rollers with adjustable intermediate space, one roller taking up the dough and the other roller taking up the bran, and each roller being equipped with a scraper, while one or more inlets for yeast and brine are present. Section C comprises transport means for supplying baking moulds, and discharging the moulds to the section D, and measuring means for filling the moulds with dough, and stopping the supply of dough when the baking mould has received a definite amount of dough. Section C comprises an oven provided with three in-line openings for the introduction, passage and discharge of baking moulds, and a cage rotatable about a horizontal axis in each section. Tunnels are suspended from the cage rods for receiving the baking moulds, the tunnels of both cages extending into each other, and successively contacting the openings during rotation of the cages, while transport organs, whose operation is coordinated with the rotation of the cages, are provided for passing the baking moulds through the tunnels of the oven parts.
Patent GB-1050609-A (GB)
IPC: B08B3/04
Abstract: 1,050,609. Conveyers. DETREX CHEMICAL INDUSTRIES Inc. June 29, 1965, No. 27407/65. Heading B8A. [Also in Divisions C7 and F4] A vertical helical jigging conveyer for effecting incremental movement of small parts or other material, usually upwardly, has the helix 22 formed of helical passages for heat exchange fluid arranged horizontally side by side, there being flexible manifolds 50, 60 at each end of the track for inlet and outlet of the fluid. The helical track is mounted on a central hollow cylinder 24 carried by vibratory mechanism 18 and vertical stanchions 26 are spaced around the outside of the track. The helical passages may comprise tubes 42, Fig. 3 (not shown), spot welded together and supported by brackets 44. The small parts to be treated, e.g. cleaned, degreased or coated are supplied by a belt 30 to a shoot 32 leading to the inlet 28 of the track and may be flushed or coated by liquid supplied through a pipe 40. From the exit end 34 of the conveyer they pass to a belt 36. Volatile cleaning &c. liquid is condensed by a coil 38. The heating tubes can be of square cross-section welded at the corners to form a grooved serrated surface for the helix. The track may be formed of a top helicallyridged helix welded to a flat bottom sheet providing passages of semi-circular crosssection. The helix can have segmental fins struck up at their forward edges to kick the parts forwardly as the helix vibrates.
Patent GB-1050929-A (GB)
IPC: F16D25/10
Abstract: 1,050,929. Friction clutches. TWIN DISC CLUTCH CO. May 27, 1965 [May 28, 1964], No. 22498/65. Heading F2C. A friction clutch 36 is lightly engaged by an annular piston 21 which is slidably mounted on an annular extension 23 of a movable cylinder 7 and forming therewith a relatively small diameter chamber 21a; the cylinder 7 co-operates with a piston 2 fast on an input shaft 1 to form a chamber C2 to which pressure is supplied to provide full clutch engagement. Liquid is supplied through a passage 50 in the input shaft 1 to a passage 51 in a wall of the cylinder 7 whence relatively unrestricted flow is permitted to the chamber 21a through a non-return valve 52 and a passage 58. Liquid is supplied to the chamber C2 through a restricted orifice 60 downstream of the valve 52 and a larger orifice 61 upstream of this valve, the passage to the chamber C2 provided by both orifices 60, 61 providing a greater restriction to flow than is provided by the path to the chamber 21a. Thus on supplying pressure liquid to the passage 50 the piston 21 is first urged into engagement with the clutch plates to give light engagement, and thereafter chamber C2 reaches the supply pressure, whereupon the pressure in chamber 21a increases to a value considerably above this. Cylinder 7 will gradually move to the right until it bears against the piston 21, at which time the pressure in chamber 21a has fallen to the supply pressure. As shown the arrangement is applied to a double clutch, a similar piston 20 being mounted on the other side of the cylinder 7.
Patent GB-1051063-A (GB)
IPC: F16J9/20
Abstract: 1,051,063. Pistons; stuffing-box substitutes. H. P. CORNELIUS. June 7, 1963 [June 20, 1962], No. 23755/62. Headings F2B and F2T. A scraping ring assembly for a piston engine comprises a main ring 2 which produces a force in a direction against a cylindrical surface and has an arcuate, non-resilient scraping lamella 6, 8 pressed against the surface by the force. As applied to a piston 10 having grooves 12, the main ring 2 is located in a groove and split so as to be able to apply a force resiliently in the direction of the cylinder surface. The ring has one or more annular grooves 4 which receive the scraping lamella which are pressed against the surface by the main ring. When the lamella are worn, they can be easily withdrawn and replaced without removing the main ring from the groove. The groove is slightly inclined and the lamella are conically shaped. The main ring may be provided with oil drainage slots and a projecting rim 38 which prevents the main part of the ring 30 touching the cylinder surface when the lamella are worn. Fig. 5 shows a scraping ring for a piston rod, the main ring 40 having one or more internal annular grooves for the lamella 42. The ring 40 may be in two or more parts and have an external groove for a spring which acts on the ring to press the lamella against the surface of the rod. The lamella may be held by a clamping device on the top or bottom of the ring.
Patent GB-1053082-A (GB)
IPC: C09B23/08
Abstract: 1,053,082. Sensitizing photographic silver halide materials. EASTMAN KODAK CO. June 10, 1964 [June 10, 1963], No.23972/64. Heading G2C. [Also in Divisions C2 and C4] Photographic silver halide emulsions are sensitized with cyanine dyes of the formulae:- wherein R represents alkyl, cycloalkyl, aryl or haloaryl, R<SP>1</SP>, R<SP>3</SP>, R<SP>4</SP> and R<SP>5</SP> each represent alkyl or substituted alkyl, X represents an acid airon, m represents 0 or 1, n represents 1, 2 or 3, p represents 1 or 2, d represents 1 or 2, and Z and Q each represent the non-metallic atoms necessary to complete a heterocyclic nucleus containing 5 or 6 atoms in the ring.
Patent GB-1227518-A (GB)
IPC: C04B41/88
Filed: 1969-05-13
Abstract: 1,227,518. Ceramics. R.C.A. CORPORATION. 13 May, 1969 [20 May, 1968], No. 24344/69. Heading C1J. [Also in Division C7] A titanate member is made by mixing (per cent by weight) BaTiO 3  74.90, CaTiO 3  5À92, SrTi0 3  10À16, CaZr03 5.72, MgZr0 3  1.38, CeO 2  0À49, UO 3  1À43 in an organic vehicle comprising toluene 148, isopropanol 180, N-alkyl trimethylene diamine 2, dibutyl phthalate 64, vinyl butyrol resin 56, epoxy resin 25, and methylethyl ketone 25, drying, pressing and then firing at 2200‹ F.
Patent GB-1228553-A (GB)
IPC: C08F8/20
Filed: 1969-07-10
Abstract: 1,228,553. Chlorinating P.V.C. POZZI FERRANDINA S.p.A. 10 July, 1969 [20 July, 1968], No. 34915/69. Addition to 1,200,711. Heading C3P. The dry chlorination of P.V.C. is effected with gaseous chlorine and a photochemically active source in the presence of a chlorination carrier and gaseous hydrogen in an amount up to 10% by wt. of the chlorine. The irradiation may be applied to the reacting mixture or just to the chlorine and optionally hydrogen at the reactor inlet. Chloroform and carbon tetrachloride are used as carriers.
Patent GB-1234330-A (GB)
IPC: G03B13/20
Filed: 1969-08-18
Abstract: 1,234,330. Binocular rangefinder. POLAROID CORP. Aug.18, 1969, No.41069/69. Headings G2A and G2J. A binocular rangefinder, which may be used in a camera, comprises a partially reflective planar element 22, Fig.3, angled such that light from a distant object is visible to the viewer therethrough and light from the two alternately energized lamps L 1  L 2 , Fig.1, is also rendered visible by deflection via diffusing members 18, 19 reticles 12, 16 and lenses 20, 21 all contained in tubular housings 10, 14. In use the reticular images 26, 27 are brought into co-incidence by moving the housing 14 in an arc about its point 36 by means of a leaf spring 40 and a screw 38 which also acts as a pointer for an arcuate scale 44 calibrated for the range of the distant object or as applied to a camera the adjustments are co-ordinated directly with the focusing of the camera objective.
Patent GB-1239018-A (GB)
IPC: H01L21/00
Filed: 1968-05-24
Abstract: 1,239,018. Semi-conductor devices. V. I. STAFEEV. 24 May, 1968, No. 24895/68. Heading H1K. A semi-conductor device comprises a plurality of current-controlled negative resistance diodes formed in a single wafer of high resistivity material, each diode having a single PN junction and the diode junctions being placed by not more than four diffusion lengths. The substrate may be of high resistivity N- type silicon doped with gold or may be a semiinsulator, and the P-type regions may be produced by diffusion. It is stated that the forward parameters of the diodes are determined mainly by the substrate material and not by the quality of the junction. The diodes may be arranged to form a neuristor, a shift register, a delay line, or a memory device. The diodes may be made conductive by injecting carriers, by a magnetic field, or by light or other radiation. In a neuristor device the diodes are arranged with a resistor and a capacitor to form a relaxion circuit, the current flowing in one diode initiating the conduction of the next diode. The capacitors may be formed using a strip of leaky dielectric deposited over the line of diodes. A single long P-type region with a distributed capacitor-resistor may be utilized in place of a series of separate diodes. A double row of diodes may be utilized to form a neuristor.
Patent GB-1250338-A (GB)
IPC: B01F27/91
Filed: 1968-10-23
Abstract: 1,250,338. Mixing liquids. H. THEILEMANN. 23 Oct., 1968 [23 Oct., 1967], No. 50417/68. Heading B1C. [Also in Division G2] In making a photographic silver halide emulsion, silver nitrate solution is mixed with a gelatin-contaning aqueous halide solution by adding silver nitrate solution to a small portion of the halide solution which is moving at high speed relative to the main bulk thereof so that there is a speed differential between the two solutions. In Fig. 1, silver nitrate solution is led through pipe 11 from container 10 to impinge on that portion of the halide solution 12 being moved at high speed by stirrer 5; the stirrer may be replaced by other rotators and/or the plate 8 by a venturi in Figs. 2 to 4 (not shown). In Fig. 5, containers 26, 27 are connected alternately to a compressed air source 32, and silver nitrate solution is supplied from a container 101, mixing occurring at the junction 29; and in Fig. 6 silver nitrate solution is introduced from container 40 via pipes 45 and 47 into halide solution being pumped out of container 39 through pipe 42 and back into said container through pipe 43, mixing occurring at the intersections of pipes 42 and 45 and 43. and 47. A further pipe 46 introduces silver nitrate solution directly into the pump 41.
Patent GB-1250743-A (GB)
IPC: C07D277/68
Filed: 1970-01-30
Abstract: 1,250,743. Benzthiazole-N-oxide pigments. FARBENFABRIKEN BAYER A.G. 30 Jan., 1970 [31 Jan., 1969], No. 4562/70. Heading C4P. [Also in Division C3] The invention comprises benzthiazole-N- oxides of the general formula wherein R<SP>3</SP> is H or an aliphatie radical and n  is 1 or 2, R is carbalkoxy having 1 to 4 carbon atoms in the alkoxy portion CN, or -CO-Z, where Z is H, alkoxy or an aliphatic, araliphatic or aromatic radical; R<SP>1</SP> is NO 2 , CF 3  or -SO 2 Y where Y is an aliphatic, araliphatic or aromatic radical, an optionally substituted amino group, or is -SO 3 M, where M is H or an alkali or alkaline earth metal atom and R<SP>2</SP> is as R<SP>1</SP> and may also be CN or a group COOQ, where Q is a monovalent aliphatic, araliphatic or aryl radical. They are prepared by reacting a halonitrobenzene of the formula  wherein R<SP>1</SP> 1 , R<SP>2</SP> and R<SP>3</SP> are as above with a mercaptomethyl compound of the formula HS-CH 2 -R, where R is as above in an inert solvent and in presence of a base e.g. a tertiary amine at 20-160 C. The products are used as pigments to colour plastics in yellow, orange and brown colours.
Patent GB-1252443-A (GB)
IPC: F15C1/16
Filed: 1968-03-19
Abstract: 1,252,443. Fluid regulation. BRITISH AIRCRAFT CORP. Ltd. May 20, 1969 [March 19, 1968], No.13277/68. Heading G3H. A fluidic amplifier system comprises a vortex amplifier 20 having an input line 18 which is connected to the main supply line 10 via a pressure regulator 16, an output line 32, and a control signal line 30, the last mentioned is connected to the main line 10 via a fluid amplifier 22 which has a vent 26 and a control signal line 24. In the absence of a signal at line 24, flow from line 14 enters line 30 and so sets up a vortex in chamber 20, the outflow from line 32 being at a minimum. Upon the application of pressure to line 24, the flow in signal line 30 changes and so the outflow from line 32 increases.
Patent GB-1258550-A (GB)
IPC: C07C37/11
Filed: 1970-10-13
Abstract: 1,258,550. Production of hexachlorophene. CENTERCHEM Inc. 13 Oct., 1970 [9 March, 1970], No. 48561/70. Heading C2C. Hexachlorophene is prepared by reacting substantially equimolar amounts of 2,4,5-triehlorophenol, formaldehyde and 2,4,5-trichlorophenyl sulphate in a solvent in which the 2,4,5- trichlorophenyl sulphate has been prepared in situ by reacting 2,4,5-trichlorophenol with a sulphating agent. The reaction between 2,4,5- trichlorophenyl sulphate, 2,4,5-trichlorophenol and formaldehyde is preferably effected at 35‹ to 60‹ C. The preferred solvents are methylene chloride, ethylene chloride, chloroform, perchloroethylene, diethyl ether, dipropyl ether or dibutyl ether.
Patent GB-1259020-A (GB)
IPC: C07D215/26
Filed: 1969-05-21
Abstract: 1,259,020. 2,4 - Dihydroxyquinolines. BADISCHE ANILIN- & SODA-FABRIK A.G. 21 May, 1969 [22 May, 1968], No. 25811/69. Heading C2C.  Compounds of formula where R is H or an electron-attracting group (e.g. acyl, nitro, alkylsulphonyl or cyano), R<SP>1</SP> is H or alkali metal, X is H, halogen, NO 2 , alkyl, optionally substituted phenyl and Y is H, halogen or alkyl, or X and Y may form part of a condensed unsaturated ring system, are prepared by reacting benzoxazinones of formula with a strong base. Examples prepare 2,4- dihydroxyquinoline and its Na salt, 3-acetyl- 2,4 - dihydroxyquinoline, 3 - acetyl - 7 - nitro- 2,4 - dihydroxyquinoline and 6,8 - dichloro- 2,4 - dihydroxy - 3 - acetylquinoline. Starting material benzoxazinones prepared are 2 - acetonyl -, 2 - acetonyl - 7 - nitro - and 6,8 - dichloro - 2 - acetonyl - benzoxazinones - 4 from corresponding anthranilic acids, diketene and acetic acid or anhydride, and 2-cyanomethylbenzoxazinone - 4 from cyanoacetylanthranilic acid and acetic anhydride.
Patent GB-1264764-A (GB)
IPC: C08J9/18
Filed: 1970-05-18
Abstract: 1,264,764. Expandable thermoplastic polymer particles. DART INDUSTRIES Inc. 18 May, 1970 [2 June, 1969], No. 24016/70. Headings C3C and C3P. Expandable thermoplastic polymeric particles impregnated with a volatile organic blowing agent, which blowing agent has a boiling point lower than the softening point (as defined) of the unimpregnated particles and is a non-solvent for the unimpregnated particles, are made by impregnating the unimpregnated particles by slurrying them with the blowing agent, introducing a gaseous stream and the slurry of impregnated particles and excess blowing agent into the inlet of a recovery zone, the zone having an inlet and an outlet, flowing the gaseous stream and slurry through the zone at a rate sufficient to maintain the particles in a state of turbulent flow, maintaining the zone at a temperature above the temperature of the gaseous stream and slurry flowing therethrough and below the temperature at which the particles begin to soften such that the excess blowing agent which has not impregnated the particles is thereby vapourized, separating the gaseous stream containing the vapourized blowing agent and recovering the expandable polymeric particles from the zone in discrete free-flowing form. The polymer may be polystyrene. The blowing agent may be n- or iso-butane or n- or iso-pentane. The gaseous stream may be gaseous butane and/or pentane with an inert gas. In the Fig. the recovery zone 15 comprises a passageway 16 and a shell 17 (through which a heating medium may be circulated).
Patent GB-1289340-A (GB)
IPC: H01M50/457
Filed: 1969-10-28
Abstract: 1289340 Dry cells MATSUSHITA ELECTRIC INDUSTRIAL CO Ltd 28 Oct 1969 [28 Oct 1968] 52732/69 Heading H1B A dry cell, such as a LeclanchÚ cell, comprises a positive electrode and a negative zinc electrode with a separator therebetween which comprises 3 layers, one of which is a paper layer which is water absorbing and water retaining, another of which is a barrier membrane consisting of polyvinyl alcohol alone or polyvinyl alcohol having incorporated therein one or more materials having at least one of the properties of water absorption, water retention, swelling and adhesion, and the other of which is an electrolytic paste layer, which paste layer is on the side of the separator which faces the zinc electrode. The material incorporated in the polyvinyl alcohol may be colloidal SiO 2 , wood pulp, agar, polyacrylamide, hydroxypropyl cellulose, carboxymethyl cellulose, methyl cellulose, starch, wheat flour, corn starch or Karaya gum. In one of the separator constructions disclosed the barrier membrane is on that side of the paper layer which faces the positive electrode, and in another construction, the paper layer is on that side of the barrier membrane which faces the positive electrode. The positive electrode may comprise a mix of MnO 2 , acetylene black, NH 4 Cl, ZnCl 2  and water. The separator is wrapped around the moulded mix and placed in a zinc can. A carbon rod is then inserted in the mix.
Patent GB-1289416-A (GB)
IPC: C25D13/22
Filed: 1970-06-23
Abstract: 1289416 Protection system SIEMENS AG 23 June 1970 [24 June 1969] 30530/70 Addition to 1194815 Heading H2H [Also in Division C7] The circuit of the parent Specification, is modified by the inclusion of an arrangement which alters the current required to actuate the device in dependence upon the normal current present. The device of the parent Specification is modified by the inclusion of transformer secondaries 50, 51 and 52, feeding rectifier 53, the output current of which is fed through resistor 55. The voltage developed across resistor 55 is a measure of the normal operating current drawn from the mains. This voltage is fed to the base of a transistor 32, whose emitter collector resistance therefore varies in dependence upon the normal operating current through an electrolytic forming device 2. Resistance 32 causes the emitter voltage of transistor 34 to be varied, and therefore the firing point of the control circuit.