baber/WOPTO huggingface dataset:
Patent NZ-510434-A (NZ)
Title: Heterocylic substituted quinazoline derivatives useful as VEGF inhibitors
Inventor: HENNEQUIN LAURENT FRANCOIS AND
IPC: A61P9/10
Filed: 1999-10-05
Abstract: A quinazoline derivative or a salt thereof has the formula (II) wherein: ring C is an optionally saturated 5-6-membered heterocyclic moiety containing 1 to 3 heteroatoms selected from O, N or S; Zb is -O- or -S-; R1 is hydrogen, alkyl, alkoxymethyl, di(alkoxy)methyl, alkanoyl, trifluoromethyl, cyano, amino, alkenyl, alkynyl, or an optionally substituted phenyl, benzyl, phenylalkyl or an optionally saturated 5-6-membered heterocyclic group moiety containing 1 to 3 heteroatoms selected from O, N or S; n is 0 to 5; R2 is hydrogen, hydroxy, halogeno, cyano, nitro, trifluoromethyl, C1-3 alkyl, C1-3 alkoxy, C1-3 alkylsulphanyl, -NR3R4 or R5X1 provided that R2 is not optionally substituted alkyl, halogen, phenoxy or phenylalkoxy; R3 and R4 are independently hydrogen or alkyl; X1 is a direct bond, -CH2-, -OCO-, carbonyl, -S-, -SO-, -SO2- , -NR6CO-, -CONR7-, -SO2-NR8- or -NR9-; R5 is H, optionally substituted C1-5 alkyl, C1-5 alkyl- X2COR11, C1-5 alkylX3R16, C1-5 alkyl-X4-C1-5 alkyl-X4R22, R28, C1-5 alkyl-R28, C2-5 alkenyl-R28, C2-5 alkynyl-R28, R29, C1-5 alkyl-R29, C2-5 alkenyl-R29, C2-5 alkynyl-R29, C1- 5 alkyl-X4-R29, C2-5 alkenyl-X4-R29, C2-5 alkynyl-X4-R29, C1- 3 alkyl-X4-C1-3 alkyl-R29, C1-3 alkyl-R54-C1-3 alkyl-X4R55; X2 is O or NR12; X3 is -O-, -OCO-, -S-, -SO-, -SO2-, -NR17CO-, -CONR18-, -SO2- NR19-, -NR20SO2- or -NR21-; X4 is -O-, -S-, -SO-, -SO2-, -NR23CO-, -CONR24-, -SO2-NR25-, -NR26SO2- or -NR27-; R28 is an optionally substituted saturated 5-6-membered heterocyclic group moiety containing 1 to 2 heteroatoms selected from O, N or S; R29 is optionally substituted pyridone, phenyl or an aromatic 5-6-membered heterocyclic group moiety containing 1 to 3 heteroatoms selected from O, N or S and R6 to R9, R11, R12, R16 to R27, R54 and R55 are as defined in the specification. The compounds produce an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals.
Patent NZ-518543-A (NZ)
Title: Saw apparatus and feed apparatus therefor
Inventor: MCIVOR PETER STEPHEN
IPC: B27B5/30
Filed: 2000-09-29
Abstract: A saw apparatus (10) comprising: a saw bench (12) having a major support device (14) and a minor support device (16) comprising respective rows of rollers (14a, 14b and 16a), for supporting a length of material to be cut on a plane of the saw bench (12); a feed device (18) for feeding a length of material to be cut in a direction of feed Y relative to the saw bench (12), while being supported by the saw bench (12), and while the length of material is being cut, and a circular saw blade assembly (50) comprising: a base member (52) mounted relative to the saw bench (12) so as to be movable in a transverse direction X across the direction of feed Y, and a blade drive assembly for rotatably mounting a circular saw blade (56) on the base member (52) at a predetermined angle Alpha relative to the transverse movement direction X of the base member (52) in the plane of the saw bench (12).
Patent NZ-519049-A (NZ)
Title: Plant for liquefying natural gas
Inventor: REIJNEN DUNCAN PETER MICHAEL
IPC: F25J1/00
Filed: 2000-11-29
Abstract: Plant (1) for liquefying natural gas comprising a main heat exchanger (10) in which the natural gas (5) is liquefied by means of indirect heat exchange with evaporating refrigerant, and a refrigerant circuit (20) in which evaporated refrigerant is compressed (23a, 23b) and liquefied to produce liquid refrigerant that is used in the main heat exchanger (10), wherein the refrigerant circuit (20) includes a compressor train (23a, 23b) consisting of at least one compressor (65a-67b) driven by an electric motor (83a, 83b).
Patent NZ-519959-A (NZ)
Title: A virtual token carrying rules of use, capabilities and token relational information
Inventor: HAY BRIAN ROBERT
IPC: G06Q20/36
Filed: 2000-12-20
Abstract: A virtual token represents an item, and includes embedded data defining rules and/or capabilities that apply to the use of the item. A virtual token may include graphical image data which is used to generate a display on a computer, whereby selection of the display allows the item represented by the virtual token to be used. A virtual token may contain instructions for sending access requests to a location on a communications network. A system for handling virtual tokens includes a clearing and routing house for routing token access requests, authenticating and generating tokens, and maintaining container structures for tokens. The system also includes connectors installed in a communications network for creating, controlling and managing items represented by tokens, and device clients for executing token components that issue access requests to the clearing and routing house.
Patent NZ-520160-A (NZ)
Title: Studded footwear
Inventor: KELLY PAUL ANDREW
IPC: A43B5/02
Filed: 2001-11-14
Abstract: A shoe stud (1, 101) for a sports shoe has a ground-engaging part and a multi-start threaded spigot (5, 105) for engagement in a complementary socket (37, 137) on a receptacle (2, 102) secured in the shoe sole or heel. The stud and receptacle also have a locking device, which interengages when the spigot is fully inserted into the socket, to resist unscrewing. In order to ensure that the stud takes up a precise position relative to the receptacle, which may be needed if the stud is not rotationally symmetrical, the stud and receptacle have means (11, 12; 111, 112) to determine the initial position of the stud relative to the receptacle, and means (13, 113) to determine the final position of the stud relative to the receptacle. Determination of the initial position may be provided by a thread (12, 112) and complementary groove (11, 111) of the screw-thread connection which are of different dimensions from the others.
Patent NZ-521097-A (NZ)
Title: Waste disposal apparatus and method
Inventor: MANN LANCE
IPC: C02F1/461
Filed: 2002-09-02
Abstract: A waste water treatment apparatus (10) including an electrolysis chamber (13) adjacent a holding chamber (14), a waste inlet (17) to the electrolysis chamber, a halide salt supply to the electrolysis chamber, at least one pair of electrodes (21) disposed in the electrolysis chamber, at least the anodes of the electrodes being oriented whereby evolved gases at the anode promote a vertical circulation of waste in the electrolysis chamber, electrical supply means (22) for the electrodes, a conduit (20) having an inlet adjacent the bottom of the electrolysis chamber and an outlet to the holding chamber at a selected level of the electrolysis chamber, and discharge means (27, 30, 31) associated with the holding chamber.
Patent NZ-525171-A (NZ)
Title: O-substituted 6-methyl-tramadol derivatives
Inventor: BUSCHMANN HELMUT
IPC: A61P25/08
Filed: 2001-09-28
Abstract: O-substituted 6-methyl-tramadol derivatives, methods for producing them, medicaments containing these compounds and to the use of O-substituted 6-methyl-tramadol derivatives for producing medicaments for treating pain.
Patent NZ-526619-A (NZ)
Title: Extrudable polymethylmethacrylate compositions for solid surface applications
Inventor: DIAO BEIBEI
IPC: C08K3/00
Filed: 2002-01-30
Abstract: Solid surface material is prepared from an extrudable composite material comprising a matrix of at least one acrylic resin and a filler dispersed in the matrix, the acrylic resin comprising an acrylic epoxy-functional copolymer as a matrix resin crosslinked with a straight or branched chain aliphatic carboxylic acid or anhydride of such acid is disclosed.
Patent NZ-528648-A (NZ)
Title: Altering animal waste composition
Inventor: LEDGARD STEWART FRANCIS
IPC: A61K9/00
Filed: 2003-10-02
Abstract: A delivery device for altering the composition of animal waste, characterised in that the delivery device delivers to an animal one or more treatment substances that can directly or indirectly affect the conversion of nitrogen containing compounds in animal waste, once the waste is excreted from the animal. Also disclosed is a method of altering the composition of animal waste, characterised by the step of introducing to an animal one or more treatment substances that can directly or indirectly affect the conversion of nitrogen containing compounds in animal waste, once the waste has been excreted from the animal.
Patent NZ-531243-A (NZ)
Title: Substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-A]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-A]pyrimidin-5(1H)one derivatives
Inventor: GALLET THIERRY
IPC: A61P3/04
Filed: 2002-09-19
Abstract: Disclosed are pyrimidone derivatives of formula (I), wherein: X is two hydrogens, a sulphur, an oxygen or an alkyl and a hydrogen, Y is a bond, a ethenylene, an ethynylene, an oxygen, a sulphur, a sulfonyl, a sulfoxide, a carbonyl, a hydroxyiminomethylene, a dioxolan, an optionally substituted nitrogen or methylene group, R1 is a 2, 3 or 4-pyridine ring optionally substituted by a cycloalkyl, alkyl, alkoxy, benzyl or halogen, and the remaining substituents are defined herein. The compounds are used for the manufacture of medicaments for treatment of diseases caused by abnormal GSK3-beta, or GSK3-beta and cdk5/p25 activity.
Patent NZ-537439-A (NZ)
Title: Controlling anomalous thermal expansion of materials
Inventor: KEPERT CAMERON JOHN
IPC: G02B1/02
Filed: 2003-07-04
Abstract: A method for controlling the thermal expansion behaviour of a material is disclosed, which comprises the step of incorporating into the material a component including one or more diatomic bridges, wherein each of the one or more diatomic bridges extends between two atoms in the component, and wherein each of the diatomic bridges has at least one vibrational mode that causes the two atoms on either side of the bridge to be moved together to a similar or greater extent than competing vibrational mode(s) that cause the two atoms on either side of the bridge to be moved apart. The bridge may also be a polyatomic bridge. New materials and devices comprising a plurality of such diatomic and polyatomic bridges are also defined.
Patent NZ-538193-A (NZ)
Title: New process for the synthesis of (7-methoxy-1-naphthyl)acetonitrile and its application in the synthesis of agomelatine
Inventor: SOUVIE JEAN-CLAUDE
IPC: C07C233/18
Filed: 2005-02-11
Abstract: A process for the industrial synthesis of (7-methoxy-1-naphthyl)acetonitrile of formula (I) which is useful in the production of agomelatine, or N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide is disclosed, wherein the process comprises an initial step of reacting (7-methoxy-3,4-dihydro-1-naphthalenyl)acetonitrile of formula (III) with a hydrogenation catalyst in the presence of an allyl compound, then the steps of filtration and evaporation to obtain (7-methoxy-1-naphthyl)acetonitrile of formula (I).
Patent NZ-540440-A (NZ)
Title: Substituted dihydrophenanthridinesulfonamides
Inventor: MOLINARI ALBERT JOHN
IPC: C07D405/04
Filed: 2003-12-02
Abstract: Disclosed herein are substituted dihydrophenanthridinesulfonamides of formulae (I) or (II) wherein the variables are as defined in the specification, or a pharmaceutically acceptable salt thereof which are useful for the treatment of the inflammatory component of diseases and are particularly useful in treating atherosclerosis, myocardial infarction, congestive heart failure, inflammatory bowel disease, arthritis, type II diabetes, and autoimmune diseases such as multiple sclerosis and rheumatiod arthritis.
Patent NZ-540768-A (NZ)
Title: Benzamide derivatives as oxytocin agonists and vasopressin antagonists
Inventor: HUDSON PETER
IPC: C07D487/04
Filed: 2004-02-12
Abstract: Compounds of formula 1 or pharmaceutically acceptable salts thereof are V1a receptor antagonists and are useful in the manufacture of medicaments for the treatment of primary dysmenorrhoea, pre-term labour, hypertension, Raynauld's disease, brain oedema, motion sickness, small cell lung cancer, depression, anxiety, hyponatremia, liver cirrhosis and congestive heart failure. Certain novel compounds of formula 1 are disclosed.
Patent NZ-545785-A (NZ)
Title: Crystalline form of bis [(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoicacid] calcium salt
Inventor: BOOTH REBECCA JANE
IPC: A61K31/505
Filed: 2004-09-08
Abstract: Disclosed is a crystalline hydrated from of the compound bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl] (3R,5S)-3,5-dihydroxyhept-6-enoic acid] calcium salt, as shown in formula I, having an X-ray powder diffraction pattern as described. Also disclosed is a process for producing the amorphous compound from the crystalline form above, the use of the crystalline form to aid isolation of the amorphous form, and the use to recover the compound from waste solutions. Also disclosed is a process for the manufacture of the crystalline form, and the use of the crystalline from for treating diseases or disorders where inhibition of HMG CoA reductase is beneficial.
Patent NZ-549698-A (NZ)
Title: Stereoselective bioconversion of aliphatic dinitriles into cyano carboxylic acids
Inventor: BURNS MICHAEL PAUL
IPC: C12P41/00
Filed: 2005-04-01
Abstract: A process for preparing (S)-3-aminomethyl-5-methylhexanoic acid (pregabalin) is disclosed which comprises the steps of: (a) contacting 2-isobutyl-succinonitrile with an enzyme catalyst having nitrilase acitivity in a reaction medium; (b) recovering (S)-3-cyano-5-methylhexanoic acid from the reaction medium; (c) converting (S)-3-cyano-5-methylhexanoic acid into an acid salt; and (d) hydrogenating the acid salt to form (S)-3-aminomethyl-5-methylhexanoic acid (pregabalin). A method for preparing (S)-3-cyano-5-methylhexanoic acid which is a useful intermediate in the synthesis of pregabalin is also disclosed. Pregabalin can be used for treating certain cerebral diseases, for example, in the treatment and prevention of seizure disorders, pain, and psychotic disorders.
Patent NZ-550759-A (NZ)
Title: Automatic changeover regulator, Automatic changeover regulator, to allow for connection to reserve container while main container can be refilled
Inventor: OLDS CHARLES M
Filed: 2003-12-09
Abstract: A pressure regulator (10) includes a changeover regulator (12) with plural inlets (not shown in this view). Inside the regulator, each inlet has a closure member (62) connected to a diaphragm (100) for control of the closure members (62) in response to pressure inside the regulator (12). Biasing members (56) are stabilized in position by either an apertured plate (102), a cup (104) or both. A changeover handle (19) depresses one spring (56) or the other to bias one closure member (62) open to admit gas from the associated inlet.
Patent NZ-551745-A (NZ)
Title: Treatment apparatus for applying electrical impulses to the body of a patient
Inventor: COLTHURST JAMES
IPC: A61N1/32
Filed: 2004-10-28
Abstract: A treatment device for applying electrical impulses to a living body through the skin, for treating a variety of clinical conditions includes a pair of electrodes for contact with the skin; a waveform generator for repeatedly generating an AC waveform for applying electrical impulses through the electrodes to the skin for treating the living body; a detector for detecting skin impedance and for generating detection signals representing the skin impedance; means responsive to the detection signals for monitoring the responsivity of the skin; and indicator means activated by the monitoring means for generating a first indication when a predetermined level of responsivity is reached, and for generating a second indication when a predetermined treatment has been administered. Treatment apparatus for applying electrical impulses to a living body through the skin, for treating a variety of clinical conditions, includes the above a treatment device, means responsive to the detecting signals for producing output data representing the responsivity of different zones of a pre-determined area of the body; a store for the output data; and means for generating a treatment map of the different zones on the basis of the output data and for selecting a treatment zone from amongst the different zones based on an evaluation of the treatment map to select the zone of greatest responsivity. A treatment system for the treatment of a living body, includes the above treatment device with the treatment device including a processor; a computer having a memory for storing patient records; means for permitting communication between the treatment device and the computer for transmitting patient information to and receiving patient information from the computer; and means for receiving a smart card including a unique patient ID and for enabling the said communication to access the patient records associated with the unique patient ID.
Patent NZ-556312-A (NZ)
Title: Container with two packs joined by straps in a Jacob's Ladder arrangement
Inventor: BRAY ANDREW JONATHAN
IPC: B31B50/64
Filed: 2006-01-25
Abstract: A package comprises first and second packs Pl, P2 each capable of containing items. Each pack has a first face Fl, Fl' bound by a first edge El, El' and a second edge E2, E2'. The first and second packs Pl, P2 are connected by first and second straps Sl, S2. In a first position of the packs the first faces Fl, Fl' of each pack face each other with the first edges El, El' of the first and second packs adjacent each other and the second edges El, E2' of the first and second packs adjacent each other. The first and second straps Sl, S2 extend across the first faces Fl, Fl' of the packs, the first strap Sl is hinged relative to the first pack at the first edge El of the first pack and hinged relative to the second pack at the second edge E2' of the second pack, and the second strap S2 is hinged relative to the second pack P2 at the first edge El' of the second pack and hinged relative to the first pack at the second edge of the first pack. When connected together by the straps Sl, S2, the first and second packs Pl, P2 are moveable, one relative to the other between at least the first position, a second position in which the second pack P2 is rotated relative to the first pack Pl about the first edge El and a third position in which the second pack P2 is rotated relative to the first pack Pl about the second edge E2'.
Patent NZ-560869-A (NZ)
Title: Porcine helicobacter infection
Inventor: ELLIS JOHN
IPC: A01N63/00
Filed: 2006-02-23
Abstract: Disclosed is a method of producing a porcine animal model of gastroesophageal ulceration (GEU) of the pars esophagea, the method comprising: (a) isolating Helicobacter pylori or H pylori-like organism (HPLO) from a porcine subject to produce an H pylori or HPLO isolate; (b) administering the H pylori or HPLO isolate to a gnotobiotic piglet in an amount sufficient to cause H pylori or HPLO infection in the piglet; and (c) feeding the piglet a milk-replacement diet that contains a dietary source of fermentable carbohydrate under conditions sufficient for producing GEU of the pars esophagea. Also disclosed is the use of the porcine animal model in methods for identifying compounds capable of treating or preventing a Helicobacter pylori or H. pylori-like organism infection.
Patent NZ-562141-A (NZ)
Title: Metal-coated steel strip comprising a coating of an aluminium-zic-silicon alloy that contains magnesium
Inventor: LIU QIYANG
IPC: C23C2/06
Filed: 2006-04-05
Abstract: Disclosed is a steel strip having a metal coating on at least one surface of the strip, which is characterised in that the coating includes aluminium-zinc-silicon alloy that contains magnesium and the coating has small spangles, and wherein the alloy optionally contains strontium andor calcium. Also disclosed is a meth of forming the coating, which includes the steps of: successively passing the steel strip through a heat treatment furnace and a bath of molten alloy which includes magnesium; heat treating the steel strip in the heat treatment furnace; and hot-dip coating the strip in the molten bath and forming a coating of the alloy with small spangles, on the steel strip.
Patent NZ-565846-A (NZ)
Title: Medicaments containing famotidine and ibuprofen and administration of same
Inventor: TIDMARSH GEORGE
IPC: A01N37/10
Filed: 2006-07-18
Abstract: Disclosed is an oral dosage form comprising ibuprofen and about 24 mg to about 28 mg of famotidine, wherein the ibuprofen and the famotidine are combined in a ratio in the range 29: 1 to 32: 1 with at least one excipient for the treatment of acute pain, dysmennorhea, or acute inflammation.
Patent NZ-569487-A (NZ)
Title: Mattress for adjustable bed
Inventor: GLADNEY RICHARD
IPC: A47C20/04
Filed: 2003-09-29
Abstract: An adjustable bed comprising: a mattress; a pivoting member configured as a sleeve attached to a major surface of the mattress; an articulated bed frame; means attached to the pivoting member for securing the pivoting member to the articulated bed frame. The securing means may be a grommet. (62) Divided Out of 539105
Patent NZ-570597-A (NZ)
Title: Method and device for providing location based content delivery
Inventor: GHANI ROD
IPC: H04M11/00
Filed: 2007-01-19
Abstract: A system and a method for providing location based content delivery. The system comprises a server (12) located at a first location; a hand-held electronic device (14) located at one location of the corresponding plurality of locations and a processing device (18) communicatively coupled to the hand-held electronic device. The server includes memory and data stored in the memory relating to a plurality of requests for services at a location other than the first location. The hand-held electronic device is configured for communicating via a wireless network with the server to receive data relating to a prioritized list of the plurality of requests for services; storing the first data in a database resident on the hand-held electronic device, receiving updated data regarding the provision of services for updating the data stored in the memory, and determining if a data connection is available to the server, and (i) transmitting the updated data to the server substantially immediately when the updated data becomes accessible if a data connection to the server is available, or (ii) storing the updated data in the local database and automatically transmitting the updated data to the server at a later time when the data connection becomes available. The processing device includes a credit card swipe slot configured to allow swipe of credit cards in a credit card capture device (24).
Patent NZ-577209-A (NZ)
Title: ACYLAMINOPYRAZOLES AS Fibroblast Growth Factor Receptor INHIBITORS
Inventor: FOOTE KEVIN MICHAEL
IPC: C07D409/12
Filed: 2007-12-20
Abstract: Disclosed are acylaminopyrazole compounds according to the structure of Formula I, wherein A is a substituted aryl group and B comprises an aryl or heteroaryl ring bonded to a heterocycle. Specific examples of compounds of Formula I include: N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]benzamide, N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide, 4-(4-Cyclobutylpiperazin-1-yl)-N-[5-[(3,5-dimethoxyphenyl)methoxy]-2H-pyrazol-3-yl]benzamide, and N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-2-(4-methyl-3-oxopiperazin-1-yl)pyrimidine-5-carboxamide, The disclosed compounds are used in the treatment of cancer and other therapies involving the production of a fibroblast growth factor receptor inhibitory effect.