Patent SG-11201900866Y-A (SG)
Title: Anti-ageing pharmaceutical preparation
Inventor: WEHLING PETER
IPC: A61P39/00
Filed: 2017-05-11
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 22 February 2018 (22.02.2018) WIP0 I PCT omitia °nolo olimin mom mom ow (10) International Publication Number WO 2018/033226 Al (51) International Patent Classification: A61K 35/14 (2015.01) A61P 17/00 (2006.01) A61K 35/16 (2015.01) A61P 17/18 (2006.01) A61P 29/00 (2006.01) A61P 39/00 (2006.01) (21) International Application Number: TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (22) International Filing Date: (25) Filing Language: (26) Publication Language: (30) PCT/EP2017/000574 11 May 2017 (11.05.2017) English English EP EP EP Published: — with international search report (Art. 21(3)) Priority Data: 16 001 807.3 17 August 2016 (17.08.2016) PCT/EP2016/001887 14 November 2016 (14.11.2016) PCT/EP2016/001888 14 November 2016 (14.11.2016) O co O O (71) Applicant: ORTHOGEN AG [DE/DE]; Ernst-Schnei- der-Platt 1, 40212 Diisseldorf (DE). (72) Inventors: WEHLING, Peter; Pigageallee 2a, D-40597 Diisseldorf (DE). REINECKE, Julio; Kamerunstrasse 20, 50733 Köln (DE). (74) Agent: KONIG, Gregor et al.; Monchenwerther Str. 11, 40545 Diisseldorf (DE). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (54) Title: ANTI-AGEING PHARMACEUTICAL PREPARATION (57) : The present invention provides a pharmaceutical preparation for use by injection into the skin, wherein the pharmaceu- tical preparation is preparable by a production method comprising the steps of providing a liquid collected from an organism, which liquid comprises cellular constituents of blood, providing a vessel or containment means, said vessel or containment means having an internal surface, and contacting said liquid with said vessel or containment means, wherein (a) said production method further com- prises the step of incubating said liquid in said vessel or containment means for an incubation time, and optionally removing cellular constituents of said liquid after said incubation, (b) said liquid comprises exosomes, and said production method further comprises the steps of concentrating said exosomes and optionally removing cellular constituents of said liquid after said concentration, or the step of isolating said exosomes, or (c) said production method further comprises the step of avoiding incubation of said liquid, and the step of removing cellular constituents of said liquid contacted with said vessel or containment means.