baber/WOPTO huggingface dataset:
Patent CA-2433800-A1 (CA)
Title: Antibodies to insulin-like growth factor i receptor
Inventor: CORVALAN JOSE R
IPC: C12N5/06
Filed: 2001-12-20
Abstract: The present invention relates to antibodies and antigen-binding protions thereof that specifically bind to insulin-like growth factor I receptor (IGF - IR), which is preferably human IGF-IR. The invention also relates to human anti-IGF-IR antibodies, including chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulin molecules derived from anti-IG F- IR antibodies and nucleic acid molecules encoding such momlecules. The prese nt invention also relates to methods of making anti-IGF-IR antibodies, pharmaceutical compositions comprising these antibodies and methods of using  the antibodies and compositions thereof for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-IGF-IR antibodies. The invention also relates to gene therapy methods and transgenic animals comprising nucleic acid molecules of the present invention.
Patent CA-2437894-A1 (CA)
Title: Method and apparatus for providing secure streaming data transmission facilities using unreliable protocols
Inventor: VANHEYNINGEN MARC D
IPC: H04L9/32
Filed: 2002-02-11
Abstract: The invention provides a method and apparatus for transmitting data securely using an unreliable communication protocol, such as User Datagram Protocol. In one variation, the invention retains compatibility with conventional Secure Sockets Layer (SSL) and SOCKS protocols, such that secure UDP datagrams can be transmitted between a proxy server (202) and a client computer (201) in a manner analogous to conventional SOCKS processing. In contrast to conventional SSL processing, which relies on a guaranteed delivery service such as TCP and encrypts successive data records with reference to a previously transmitted data record, encryption is performed using a nonce that is embedded in each transmitted data record. This nonce acts both as an initialization vector for encryption/decryption of the record, and as a unique identifier to authenticate the record. Because decryption of any particular record does not rely on receipt of a previously received data record, the scheme will operate over an unreliable communication protocol. The system and method allows secure packet transmission to be provided with a minimum amount of overhead.
Patent CA-2438676-A1 (CA)
Title: Single-reed wind instrument
Inventor: DUNCAN GILLIS
IPC: G10D7/06
Filed: 2003-08-25
Abstract: The present invention is a hand-held musical pipe wind instrument in which sound is produced by a single-reed and which replicates the relative scales and tone- hole arrangement found on the Scottish Highland bagpipe chanter. In its most basic embodiment , this wind instrument consists of a saxophone reed and mouthpiece attached to the upper end of a tube, and a flaring bell or sole attached to the lower end of the same tube. In th is basic embodiment, the tube comprises a plurality of holes, known as tone-holes, disposed at predetermined locations along the length of the tube, which in playing are opened and clos ed successively in predetermined configurations to achieve changes in pitch.
Patent CA-2440993-A1 (CA)
Title: Digital options having demand-based, adjustable returns, and trading exchange therefor
Inventor: LANGE JEFFREY
IPC: G06Q50/00
Filed: 2002-03-11
Abstract: This invention provides methods and systems for trading and investing in groups of demand-based adjustable return ("DBAR") contingent claims, including digital options, and for establishing markets and exchanges for such claims.  The advantages of the present invention, as applied to the establishment and operation of a DBAR digital options exchange, include the ability to offer investments whose profit and loss scenarios are comparable to those for digital options or other derivatives in traditional securities markets, without the need for options or derivatives sellers or order-matching of conventional markets. A DBAR digital options exchange of the present invention can also offer conditional investments, or limit orders, in which an investment in a state of a DBAR contingent claim (such as the price of an underlying asset or index) can be executed or withdrawn in response to the implied probability of the occurrence of that state.
Patent CA-2441849-A1 (CA)
Inventor: MORENCY MICHAEL D
IPC: H04L12/16
Filed: 2003-09-19
Abstract: A method for Internet-based intermediary computing to handle debt management plan requests, the method including the steps of: receiving respective debt management plan requests at an intermediary computer, by Internet communication, from each of a plurality of request-originating computers; processing the respective debt management plan requests to produce respective, formatted and at least partially validated debt management plan requests; using the respective, formatted and at least partially validated debt management plan requests in enabling a respective debt management plan decision at one of the intermediary computer and a creditor computer; and electronically communicating a signal of the decision to the request-originating computer.
Patent CA-2445475-A1 (CA)
Inventor: MUGFORD ROGER ARTHUR
IPC: A01K15/02
Filed: 2003-10-17
Abstract: A hand held training device capable of producing discreet clicks when operated by a user, having a means by which the user can vary the volume and/or tone of the clicks produced.
Patent CA-2446365-A1 (CA)
Title: Sulfonamides
Inventor: KNIGHT STEVEN D
IPC: A61P25/22
Filed: 2002-05-07
Abstract: The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.
Patent CA-2447461-A1 (CA)
Title: Rope of synthetic fibre with reinforcement element for frictionally engaged power transmission and rope of synthetic fibre with reinforcement element for positively engaged power transmission
Inventor: WEINBERGER KARL
IPC: D07B1/02
Filed: 2003-10-30
Abstract: The rope of synthetic fibre (30) comprises two ropes (31, 32) from synthetic fibre strands (35-37), which are arranged for the taking up of force in lengthwise direction. The ropes (31, 32) are arranged along the lengthwise direction of the rope of synthetic fibre (30) with a distance to each other and are fixed by means of a rope sheathing (33). The rope sheathing (33) exhibits a fixed link, running in the lengthwise direction of the rope of synthetic material (30), between the two ropes (31, 32). The rope of synthetic fibre (30) comprises at least one reinforcement element (34) for mechanical reinforcement of the rope sheathing (33).
Patent CA-2447860-A1 (CA)
Title: Method for shielding an electric circuit created on a printed circuit board and a corresponding combination of a printed circuit board and a shield
Inventor: ROMAHN JOERG
IPC: H01L23/552
Filed: 2002-05-17
Abstract: The invention relates to a method for shielding an electric circuit created on a printed circuit board (1) comprising a number or components (2). According to said method, a first electrically insulating layer (3) is applied to the whole surface of the printed circuit board (1) and a second earthed, electrically conductive layer (4), which acts as a shield, is then applied to the whole surface of said first electrically insulating layer (3), in such a way that suitable recesses (5) corresponding to the number of components are configured. The invention also relates to a corresponding combination of a printed circuit board (1), on which at least one electric circuit comprising a number of components (2) is created and a first electrically insulating layer (3) with a second earthed layer (4), which covers the whole surface and acts as a shield.
Patent CA-2448750-A1 (CA)
Title: Silicone composition for water-repellent coating
Inventor: SASAKI MOTOSHI
IPC: C08J7/04
Filed: 2002-05-27
Abstract: A silicone composition for a water-repellent coating comprising (A) a polydimethylsiloxane expressed by the general formula: (RO)3Si-Q-{(CH3)2SiO}n-(CH3)2Si-Q-Si(OR)3, where R is a C1 to C10 monovalent hydrocarbon group, Q is an oxygen atom or a C2 to C10 alkylene group, and n is an integer from 10 to 1000; (B) an alkoxysilane partial hydrolysate/condensate, where the alkoxysilane is described by general formula: R1xSi(OR2)4-x, where R1 is a C1 to C6 monovalent hydrocarbon group, R2 is a C1 to C6 alkyl group, and x is an integer from 0 to 3; (C) an organotitanium-based catalyst; (D) an aliphatic hydrocarbon solvent or ester-based solvent; and (E) an alcohol-based solvent.
Patent CA-2449378-A1 (CA)
Title: Vitamin b6-phosphate phosphatase
Inventor: HOSHINO TATSUO
IPC: C12R1/01
Filed: 2002-06-14
Abstract: Vitamin B6-phosphatase (VB6PP), a process for producing VB6PP and a process for producing vitamin B6 from vitamin B6-phosphate (VB6P) utilizing VB6PP an d a cell-free extract of a specific microorganism capable of producing VB6PP.< /SDOAB>
Patent CA-2453174-A1 (CA)
Inventor: ISIP AMANDO B JR
IPC: G06F17/30
Filed: 2002-07-18
Abstract: L'invention concerne un procédé de réorganisation d'un ensemble de tables dans une base de données. Ce procédé peut consister à lire une ligne de données dans une base de données ; - à analyser la ligne de données extraite de la base de données ; - à déterminer l'élimination ou la conservation de la ligne de données sur la base d'au moins une règle prédéterminée ; à recharger la ligne de données dans la base de données une fois observé que la ligne de données est conforme à au moins une règle prédéterminée ; à éliminer la ligne de données une fois observé que la ligne de données n'est pas conforme à au moins une règle prédéterminée et à recréer un indexe lié à la base de données pour inclure des codes qui correspondent à la ligne de données rechargée. Les étapes de détermination, de recharge, d'élimination et de recréation sont répétées pour chaque ligne de données de la base de données.
Patent CA-2453388-A1 (CA)
Title: Isolement du facteur viii
Inventor: TURTON THOMAS NORMAN
IPC: B01D57/02
Filed: 2002-07-15
Abstract: L'invention concerne des procédés d'isolement du facteur VIII fonctionnellement actif à l'aide d'un système de séparation membranaire comportant une membrane de séparation servant à créer un premier et un second volume interstitiel entre au moins deux membranes de restriction. Un ou plusieurs agents de stabilisation sont ajoutés à l'échantillon et/ou au volume interstitiel. Un solvant présent dans le premier volume interstitiel maintient le FVIII dans l'état de charge souhaité. L'application d'un potentiel entre les premier et second volumes interstitiels isole le FVIII d'un côté de la membrane de séparation, à l'écart des molécules non désirées présentes de l'autre côté de la membrane de séparation. On peut également substituer ces procédés à une ou plusieurs opérations d'un processus de purification classique pour isoler le FVIII natif ou recombiné.
Patent CA-2453455-A1 (CA)
Inventor: MEYER ROBERT W
IPC: D06F58/10
Filed: 2003-12-17
Abstract: A stationary dryer, useful as a clothes dryer, is provided comprising a housing enclosing a space and a stationary clothes support located within the space.  An air moving device is provided for generating an air flow through the space from an air inlet to an air outlet. An air distributor mechanism comprising a distribution plenum is positioned between the air inlet and the clothes support, with a plenum wall having a plurality of perforations therein. The perforations are sized, shaped and arranged so as to provide jets of air against the clothes support and to equalize an air flow distribution over the clothes support.
Patent CA-2455336-A1 (CA)
Inventor: PRESCOTT MARGARET FORNEY
IPC: A61P9/10
Filed: 2002-08-09
Abstract: The present invention provides peptides that selectively bind to mammalian atherosclerotic lesions. The present invention also provides methods for in vivo identification of peptides capable of binding to biomolecules as well as methods for identifying the targets of such binding moieties. Methods to diagnose or treat pathologic conditions that involve atherosclerotic lesions are also provided by the invention that involve administering to a mammal a peptide attached to a reporter molecule or a therapeutic agent, respectively.
Patent CA-2457013-A1 (CA)
Title: Disposable receptacle for animal waste
Inventor: SEIGNORET MARCEL M
IPC: A01K1/01
Filed: 2004-01-24
Abstract: A disposable animal urine receptacle used beneath an animal to catch urine or feces that is falling or projecting toward other surfaces. This innovation consists of a tray with raised edges surrounding an absorbent liner. The raised edges are angled outward to collect urine into the tray's center to be soaked up by the absorbent liner.  The absorbent liner absorbs both liquids and odours. This innovation may include a handle protruding from one side of the tray. This innovation is entirely disposable.
Patent CA-2458686-A1 (CA)
Title: Embedded quick change connector for grinding wheel
Inventor: NELSON ERIC W
IPC: B24D3/28
Filed: 2002-06-17
Abstract: An abrasive article (10) for a grinder (12) having a motor-driven, externally-threaded spindle (14). The abrasive article includes a molded abrasive disk (18) with an integrally molded fastener (22). The molded abrasive disk (18) includes abrasive particles disbursed in a binder. The molded abrasive disk (18) has a first major surface (24), a second major surface (26) and an integrally molded fastener (22). The fastener (22) has a body portion (44) with an aperture (46) and first and second ends, an outwardly extending flange with a front surface (32) at the first end, and an inwardly extending flange (47) including a single internal thread (48) at the second end. The fastener (22) is molded into the molded abrasive disk (18) so that the front surface does not extend above the first major surface (24).
Patent CA-2459849-A1 (CA)
Inventor: CHEN XIAO LIANG
IPC: F24C7/00
Filed: 2004-03-05
Abstract: The invention provides an electric fireplace flame simulating rotator with light-emitting cooling flanged slots, comprising a light source mounted within a rotatable hollow cylinder, the cylinder having a multiplicity of large flanged slots in a middle portion of the cylinder, and a multiplicity of narrower flanged slots toward each end of the cylinder, that disperse heat from the light source and through which light can be emitted from a light source to simulate larger central flames and smaller more flickering flames toward each end of the cylinder upon the cylinder being rotated about the light source, while cooling the light source by circulating more air in the middle portion of the cylinder.
Patent CA-2461740-A1 (CA)
Inventor: ADAM JEAN-MICHEL
IPC: A61K9/00
Filed: 2002-10-17
Abstract: The invention is directed to isomeric mixtures of cyclosporine analogues that are structurally similar to cyclosporine A. The mixtures possess enhanced efficacy and reduced toxicity over the individual isomers and over naturally occurring and other presently known cyclosporines and cyclosporine derivatives. Embodiments of the present invention are directed toward cis and trans-isomers of cyclosporin A analogs referred to as ISATX247, and derivatives thereof. Mixtures of ISATX247 isomers exhibit a combination of enhanced potency and reduced toxicity over the naturally occurring and presently known cyclosporins. ISATX247 isomers and alkylated, arylated, and deuterated derivatives are synthesized by stereoselective pathways where the particular conditions of a reaction determine the degree of stereoselectivity.  Stereoselective pathways may utilize a Wittig reaction, or an organometallic reagent comprising inorganic elements such as boron, silicon, titanium, and lithium. The ratio of isomers in a mixture may range from about 10 to 90 percent by weight of the (E)-isomer to about 90 to 10 percent by weight of the (Z)-isomer, based on the total weight of the mixture.
Patent CA-2462906-A1 (CA)
Title: Modifications of solid 3-sn-phosphoglycerides
Inventor: SHAW WALTER A
IPC: A61K47/24
Filed: 2002-10-11
Abstract: Methods for hydrolyzing solid ungranulated lysophosphatidylcholine with phospholipase A2 are provided. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine, monoglyceride and fatty acid, and lipid matrices of particular structure.
Patent CA-2463234-A1 (CA)
Title: Detergent compositions comprising an alkali metal carbonate salt and a water soluble-organic acid
Inventor: SCHOKKER WIEBE
IPC: C11D3/20
Filed: 2002-10-15
Abstract: A particulate laundry detergent composition which comprises a detergent base powder comprising surfactant and builder and, as separate particulate components: (a) an alkali metal carbonate salt selected from carbonate, bicarbonate, sesquicarbonate and combinations thereof; and (b) a water-solub le organic acid which, when reacted with (a) in the presence of water, generate s carbon dioxide gas; wherein the alkali metal carbonate salt, when taken separately, has a 90% dissolution time of less than 15 seconds, and the wate r- soluble organic acid has a d50 particle size which is in the range of from 1 50 to 1500 microns. The alkali metal carbonate salt preferably has an average bulk density of at most 1000 g/l. The alkali metal carbonate salt preferably has a d50 particle size of at most 250 microns. The alkali metal carbonate salt is preferably sodium and/or potassium carbonate.
Patent CA-2464094-A1 (CA)
Title: Methods for ligand discovery
Inventor: BRAISTED ANDREW A
IPC: C12Q1/68
Filed: 2002-04-24
Abstract: The present invention provides novel methods for ligand discovery. The inventive methods rely on a process termed "tethering" where potential ligan ds are covalently bonded or "tethered" to a target and subsequently identified as exemplified by the figure.
Patent CA-2467620-A1 (CA)
Inventor: TUFTE BRIAN N
IPC: F21S4/00
Filed: 2002-11-15
Abstract: A lighting apparatus (410) for illuminating side surfaces of objects or equipment including, such apparatus including a first member (414) and a second member (412). The first member (414) being at least partially transparent and the second member (412) being substantially non-transparent. A cavity (438) is formed at least partially by a portion of the first member (414), such cavity (438) being for receiving an elongated light source (416) .
Patent CA-2470415-A1 (CA)
Title: Ceramique aluminique translucide polycristalline
Inventor: CASTRO DARREN T
IPC: A61K6/06
Filed: 2002-12-06
Abstract: La présente invention concerne un matériau céramique polycristallin translucide à base d'oxyde d'aluminium. Son calibre moyen de grain n'excède pas 1 micron pour une valeur du rapport de contraste n'excédant pas environ 0,7. Ce matériau peut se présenter sous forme d'une ébauche dentaire, de prothèse dentaire ou d'un autre article dentaire ou non dentaire.
Patent CA-2470447-A1 (CA)
Title: Streptogramin derivatives, preparation thereof and compositions containing same
Inventor: PUCHAULT GERARD
IPC: A61K31/424
Filed: 2002-12-23
Abstract: Streptogramin A derivatives (I) are new.  Streptogramin A derivatives of formula (I) and their salts are new:  R1 = halo, OH, 1-6C alkoxy, N3, SCN or NR'R''; R' = H or Me; R'' = A, OA or NA'A''; A = H, 1-6C alkyl, cycloalkyl, allyl, propynyl or benzyl; A', A'' = Me; or  NA'A'' = a 4- or 5-membered ring optionally containing another heteroatom selected from N, O or S; R'1 = H; R2 = halo, 1-6C alkyl, 2-6C alkenyl, 2-6C alkynyl, phenyl, heteroaryl, 1-6C alkylthio, phenylthio or heteroarylthio; R3 = H, Me or Et; and R1+R'1 = oxo. Independent claims are also included for:  (1) a process for preparing compounds (I);  (2) polyanions derived from selected compounds (I; R2= H) (15 formulas given);  (3) a pharmaceutical composition comprising a compound (I) and optionally at least one streptogramin B derivative and/or one or more diluents or adjuvants.
Patent CA-2472012-A1 (CA)
Inventor: CHIN YEM
IPC: A61B1/04
Filed: 2002-12-13
Abstract: In one embodiment, the invention provides an imaging device having a light source, a photo-sensor and a scanning assembly. In some embodiments, the light source is fixedly mounted in the first end of an elongated sheath and is adapted for illuminating a target, and the photo-sensor is mounted on the scanning assembly, also in the first end of the elongated sheath, and is adapted to detect light energy from the target. In other embodiments, the light source is movably mounted and the detector is held stationary. In other embodiments, both the light source and the photo-sensor are movably mounted.  The scanning devices synchronously capture light energy from each of a plurality locations on the target, the light energy resulting from illumination by the light source, and synchronously digitizes the output from the photo-sensor from each of the plurality of locations on the target to generate an image of the target.
Patent CA-2472772-A1 (CA)
Title: A device for dispensing two sided adhesive tape pieces and a refill roll for the device
Inventor: LUDVIGSEN FRITS
IPC: B65H37/00
Filed: 2003-01-13
Abstract: The device has a roll (1) of a carrier strip (2) holding pieces (3) of two sided adhesive tape and wound on a hub (5) with an outer radius and provided with a circular cogging (6), a support (7) for the roll (1) comprising a stub shaft (9) with a direction of axis around which the roll rotates when dispensing tape pieces (3), a brake pawl (23) for engagement with the circular cogging (6), a pressure base (15) being in connection with the brake pawl (23) such that the engagement of the brake pawl (23) with the cogging (6) is released by pressure on the pressure base (15), a peripheral wall (10,11) extending along a part of the periphery of the roll (1), and a path for the carrier strip (2) extending past the pressure base (15) and along a part of the outside of the peripheral wall (10,11), the pressure base (15) comprising an outer sliding surface (16,17) defining a part of the path for the carrier strip (2) with the two sided adhesive tape where the path at the pressure base (15) comprises a portion with a relative sharp curve (18) with a radius of curvature being essentially smaller than the outer radius of the hub. The two sided adhesive tape (3) is of a relatively rigid material, the two sided adhesive tape (3) being separated from the carrier strip (2) when the latter passes said relatively sharp curve (18) during advance.
Patent CA-2472993-A1 (CA)
Title: Oxothieno (3, 2-b) pyridinecarboxamides as antiviral agents
Inventor: ROMINES KAREN
IPC: A61P43/00
Filed: 2003-01-14
Abstract: The invention provides a compound of formula (I) wherein G, R2, and R3 have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as processes and intermediates useful for preparing such compounds or salts, and methods of treating a herpesvirus infection using such compounds or salts.