baber/WOPTO huggingface dataset:
Patent EP-1674107-B8 (EP)
Inventor: OLESON FREDERICK B JR
IPC: A61K31/7036
Filed: 1999-09-24
Granted: 2017-01-25
Abstract: The invention provides methods for administering a therapeutically effective amount of daptomycin while minimizing skeletal muscle toxicity. The methods provide daptomycin administration at a dosing interval of 24 hours or greater. This long dosing interval minimizes skeletal muscle toxicity and allows for higher peak concentrations of daptomycin, which is related to daptomycin's efficacy. The invention also provides methods of administering lipopeptide antibiotics other than daptomycin while minimizing skeletal muscle toxicity by administering a therapeutically effective amount of the lipopeptide antibiotic at a dosage interval that does not result in muscle toxicity. The invention also provides methods of administering quinupristin/dalfopristin while minimizing skeletal muscle toxicity by administering a therapeutically effective amount of quinupristin/dalfopristin at a dosage interval that does not result in muscle toxicity.
Patent EP-1774080-B8 (EP)
Title: Spacer device
Inventor: SAMPIERO GIOVANNI
IPC: D06F39/00
Filed: 2006-06-01
Granted: 2008-04-23
Abstract: The present invention relates to a spacer device (1) adapted to be used preferably in a device for securing the oscillating assembly to the cabinet of a laundry washing machine, washing/drying machine or clothes dryer. Said spacer device (1) comprises a first portion (20), a second portion (6), and a cavity (8) for a securing screw. The spacer device (1) according to the invention is an enbloc device, preferably a multimaterial one.
Patent BR-PI0602346-B8 (BR)
Inventor: JOSHUA UTH
IPC: A61N1/05
Filed: 2006-06-26
Abstract: An attachment mechanism for a surgically implantable medical device includes one or more fasteners which may be simultaneously moved from an undeployed position to a deployed position by operation of an integral actuator. The attachment mechanism may be configured to be deactuated, and the fasteners simultaneously moved from a deployed position to an undeployed position, allowing removal or repositioning of the medical device. An applier includes a locator for detachably holding the implantable medical device, locating it at the desired position, and actuating the attachment mechanism. The applier is configured to undeploy the attachment mechanism the implantable medical device can be detached from the body tissue.
Patent BR-PI0615082-B8 (BR)
Title: Junta de condutor submarino tubular; condutor submarino e método para conexão de juntas de condutor submarino
Inventor: THOMAS A FRASER
IPC: E21B17/01
Filed: 2006-08-23
Abstract: SISTEMA DE ACOPLAMENTO DE CONDUTOR SUBMARINO PRÉ-CARREGADO. Um sistema de condutor submarino offshore tem juntas de condutor submarino, cada uma tendo um pino e uma caixa. O pino tem um perfil externo sulcado que é engatado por um elemento de travamento portado pela caixa de outra junta de condutor submarino. Um anel de acionamento engata o elemento de travamento para mover o mesmo para uma posição travada. Uma aranha retrátil suporta uma coluna do condutor submarino enquanto a nova junta está sendo ajustada. Uma ferramenta de ajuste no piso de posicionamento de condutor submarino move o anel com relação ao elemento de travamento, fazendo com que o elemento de travamento se mova para a posição travada.
Patent BR-PI0617697-B8 (BR)
Title: método e montagem de septo e de vedação de agulha com baixa resistência ao avanço de peça única
Inventor: CHRIS CINDRICH
IPC: A61M5/32
Filed: 2006-10-25
Abstract: método e montagem de septo e de vedação de agulha com baixa resistência ao avanço de peça única. um septo de baixa resistência ao avanço de peça única é fornecido para impedir escape de fluido a partir de uma agulha de introdutor durante a remoção de uma agulha como esta de uma montagem de cateter e agulha de introdutor. o septo de uma maneira geral inclui uma parte distal, uma parte proximal, uma parte de cavidade e um eixo geométrico longitudinal. a parte distal age como uma vedação primária para impedir escape de sangue a partir do cateter para dentro da montagem e é de uma maneira geral posicionada mais distante do usuário do aparelho e mais próxima do paciente. a parte de cavidade reduz atrito colocado na agulha de introdutor. a parte proximal do septo age como uma vedação secundária para impedir escape de material a partir da cavidade, veda a cavidade e limpa a agulha à medida que ela está sendo removida da montagem de cateter.
Patent BR-PI0810113-B8 (BR)
Title: método para preparação de um extrato seco de pelargonium sidoides e/ou pelargonium reniforme com solubilidade melhorada em solventes fisiologicamente compatíveis
Inventor: JOACHIM HERRMANN
IPC: A61K47/10
Filed: 2008-04-04
Abstract: extrato seco de pelargonium sidoides e/ou pelargonium reniforme, método para preparação dos mesmos, bem como preparado e produtos contendo os referidos extratos. a presente invenção refere-se a métodos de produção para obtenção de extratos secos de pelargonium sidoides e/ou pelargonium reniforrne, a extratos que possam ser obtidos de acordo com os ditos métodos, e a produtos farmacêuticos compreendendo tais extratos.
Patent AU-2006252155-B8 (AU)
Title: Mobile computer communication interface
Inventor: FREDERKING JAY
IPC: G06F1/16
Filed: 2006-12-20
Granted: 2012-03-22
Abstract: A system and method is provided for a mobile computer communication interface. One embodiment includes a mobile computer communication interface. The mobile computer communication interface comprises a transceiver operative to send and receive wireless communications to and from a host computer. The mobile computer communication interface may also comprise a touch-screen display, the touch-screen display being operative to receive inputs from a user arid remotely display outputs provided by the host computer. The mobile computer communication interface may also comprise a controller operative to wirelessly access and remotely control the host computer in response to inputs from the touch-screen display. Lcc Ln 0 C~Cf WJ C)LCoL z 0 ( u-ij oUU z -L
Patent BR-102012007980-B8 (BR)
Title: câmera
Inventor: MASATO SEITA
IPC: G03B13/32
Filed: 2012-04-05
Abstract: câmera uma câmera inclui um primeiro membro de contato de espelho que pode ser contatado com um lado do espelho, um primeiro membro de rotação girado ao redor de um primeiro eixo de rotação quando o primeiro membro de contato de espelho é contatado com um lado do espelho, um segundo membro de contato de espelho que pode ser contatado com o outro lado do espelho, e um segundo membro de rotação girado ao redor de um segundo eixo de rotação quando o segundo membro de contato de espelho é contatado com o outro lado do espelho. o primeiro eixo de rotação é formado em uma posição diferente de uma posição do primeiro membro de rotação, onde o primeiro membro de contato de espelho é provido. o segundo eixo de rotação e' formado em uma posição diferente de uma posição do segundo membro de rotação onde o segundo membro de contato de espelho é provido. os primeiro e segundo membros de contato são arranjados de modo que os primeiro e segundo eixos de rotação sejam coaxialmente posicionados.
Patent EP-1639267-B9 (EP)
Inventor: HEDMAN TORBJOERN
IPC: F16D41/08
Filed: 2004-06-04
Granted: 2008-08-20
Abstract: The device (1) has multiple cams (7), and outer and inner casings (8, 9) for maintenance of the cams. Annular friction units (18, 19) are fixed in respective grooves (16, 17) of the casing (9) and are integrated with a groove (5) of an inner ring (4) that is in contact with the cams, such that the friction units enter in friction contact with the ring or casing (9). The units have a rectangular transversal section.
Patent EP-2032160-B9 (EP)
Inventor: DEVOS NATHALIE
IPC: A61K39/095
Filed: 2007-06-08
Granted: 2011-09-14
Abstract: The present invention relates to the field of neisserial vaccine compositions, their manufacture, and the use of such compositions in medicine. More particularly it relates to processes of making novel engineered meningococcal strains which are more suitable for the production of neisserial, in particular meningococcal, outer- membrane vesicle (or bleb) vaccines. Advantageous processes and vaccine products are also described based on the use of novel LOS subunit or meningococcal outer- membrane vesicle (or bleb) vaccines which have been rendered safer and more effective for use in human subjects.
Patent EA-035519-B9 (EA)
Title: 1,3,4-thiadiazole compounds and their use in treating cancer
Inventor: FINLAY MAURICE RAYMOND VERSCHOYLE
IPC: A61P35/00
Filed: 2016-11-30
Abstract: The invention relates to compounds defined in the claims and pharmaceutically acceptable salts thereof. The invention also relates to a pharmaceutical composition for inhibiting glutaminase 1 (GLS1), comprising a compound by the invention or a pharmaceutically acceptable salt thereof. Furthermore, the invention relates to the use of a compound by the invention or a pharmaceutically acceptable salt thereof in treating a disease mediated by GLS1 and to a method for treating a disease mediated by GLS1 in a warm-blooded animal in need of such treatment, comprising administering to the warm-blooded animal a compound by the invention or a pharmaceutically acceptable salt thereof.
Patent DE-3217082-C1 (DE)
Title: Lock for safety belts
Inventor: OTZEN UWE DR DIPL-ING
IPC: B60R22/32
Filed: 1982-05-07
Granted: 1983-10-20
Abstract: In a lock for safety belts of means of air and land transport, having an opening mechanism which can be released at any time as a result of the manual actuation of a push button (16), an automatic actuation by means of an electrical signal generated by a sensor is additionally possible. An electromechanical drive, preferably an electric motor (18), engages on the push button (16) with a pulling effect and moves the latter as an alternative to manual actuation. A reduction between the electric motor (18) and a threaded spindle (20) driven by this and pulling the push button (16) by means of a threaded sleeve (24) ensures the time delay during the automatic opening of the lock. The repeatability of the delay in the event of multiple impacts in the course of an accident cycle is guaranteed in that the threaded sleeve (24) engaging with only less than half the circumference into the threaded spindle (20) is lifted off by means of an electromagnet (36) excitable by the sensor signal, so that the push button (16) is each time brought into its initial position again by springs (28). <IMAGE>
Patent DE-3528132-C1 (DE)
Title: Method for transmitting the components of a colour television signal
Inventor: EBNER ANDREAS DIPL-ING
IPC: H04N11/08
Filed: 1985-08-06
Granted: 1987-04-23
Abstract: In order to avoid the occurrence of intermodulation products and the loss of vertical resolution during the transmission of the components of a colour television signal, it is provided that a wide-band luminance signal is transmitted in each line during a first field and a narrow-band luminance signal is transmitted in each line during the following second field and the colour difference signals are added in time- or frequency-division multiplex.
Patent DE-3829640-C1 (DE)
IPC: A61K47/00
Filed: 1988-09-01
Granted: 1990-04-26
Abstract: The invention relates to transdermally applicable pharmaceutical compositions which contain glycosides as active substances and which are characterised in that ethoxylated sterols and/or C12-C30 alcohols are employed as solubilisers in lipophilic phase.
Patent DE-3840316-C1 (DE)
IPC: C04B35/00
Filed: 1988-11-30
Granted: 1990-04-19
Abstract: The invention relates to a process for the preparation of a homogeneous, finely divided ceramic powder, in which a) a solution or a suspension of substances from which the constituents of the ceramic powder are formed is prepared, b) the solution or suspension is sprayed through a nozzle into a heatable reactor, c) the solvent or suspending agent is evaporated in the reactor and solid residue particles to form, which are dried and converted into the constituents of the ceramic powder by a decomposition reaction or another chemical reaction. It is an object of the invention to indicate a process for the preparation of a finely divided and homogeneous ceramic powder which is crystalline and virtually free from water. The properties of this powder do not depend on the nature of the metal ions employed. In the process, the evaporation of the solvent or suspending agent, the drying and the calcination of the resultant residue particles and their chemical conversion into the desired ceramic proceed in a single process step. The object is achieved according to the invention in that a combustible gas, which is burnt in the reactor, is used to spray the solution or suspension.
Patent DE-4001335-C1 (DE)
Title: High-pressure plunger pump - incorporates adjustable sleeve and disc-types inlet valve
IPC: F04B53/16
Filed: 1990-01-18
Granted: 1991-01-31
Abstract: Max pressure plunger pump has delivery and intake valves coaxial to the pump cylinder and a sleeve which adjusts freely on the plunger and is supported on the plunger head end by an insert com-plete with valve seat and intake bores for the intake valve. The sleeve has a sliding bushing and the disc type intake valve has a spring loaded seal and bears on the insert fitted seat. The plunger (6) slide bushing (9) should extend to the sleeve (7) end facing the plunger head so its endface bears on the insert (12). A sealing sleeve (15) between the bushing and the flow channel limited by the insert overlaps the abutment between insert and sleeve (7).
Patent DE-4106426-C1 (DE)
Title: Processing pierce core sets for tyres - at least 1 reciprocating holder picks up core rings from automatic winder and cool or harden in store after being sepd.
IPC: B29D30/48
Filed: 1991-02-26
Granted: 1992-02-13
Abstract: An arrangement processes pierce cores consisting of rubber-covered individual steel wires wound into pierce core sets whose individual rings can be removed at the end of the winding process and which can be placed in a store for cooling or hardening. Between a discharge point on an automatic winder for Pierce core sets and the store concerned at least one reciprocating holder can be applied to pick up the Pierce core rings which are overlapped at the circumference. The holder also can expand the annular Pierce core sets on one side into individual rings; a vertically opening/closing pair of jaws relates to the holder for each individual Pierce core ring; besides one fixed pair of jaws there is at least one further pair which open/close horizontally and laterally. ADVANTAGE - The system engages the Pierce core sets from an automatic winder in short cycles and hence improves the overlapping joints, automatically separates the Pierce core sets and thus cuts out manual handling in those operations.
Patent DE-4133222-C1 (DE)
Title: Mfg. body fitting crash helmet cushion - applies deformable lining along cushioned body part, with external, longitudinal protrusions
IPC: A42C2/00
Filed: 1991-10-07
Granted: 1992-10-15
Abstract: The cushioning, protection system for a crash helmet, with rigid, external cladding with a soft, air-permeable cushion on the inside is mfd. by forming an internal ventilation system with flow passages adjacent to the cushion. A deformation layer is placed over the head etc, with longitudinal protrusions (52) along the outside, forming a preset pattern with the layer (50) in non-deformed state. The outside of the layer with the protrusions is then covered with shock load damping material. After the latter has hardened into a rigid, external cladding, the deformation layer is removed and replaced by the soft air-permeable cushion, whose thickness is the same as that of the layer between adjacent protrusions. ADVANTAGE - Improved wearer's comfort and safety.
Patent DE-4138615-C1 (DE)
Title: Car seat belt buckle holder - has grommet retaining loop, pulled through other loop cable sections, extending from seat belt buckle
IPC: B60R22/22
Filed: 1991-11-22
Granted: 1993-02-25
Abstract: The belt buckle holder consists of a cable,which is anchored to the floor to form end loops which are secured to the cable such that one loop is traversed and holds the lock of the belt, and the other one takes a grommet as socket for another connected belt. The loop (25) for the grommet (29) is drawn through the cable sections of the other loop (24) so that it is gripped below the lock (28) by the belt itself. USE/ADVANTAGE - Car seat belts,without danger of intersection during assembly.
Patent DE-4222939-C1 (DE)
IPC: A61G7/10
Filed: 1992-07-11
Granted: 1993-07-22
Abstract: A bathtub lift (2) has a bottom frame (4), a liftable and lowerable seat (6) provided with a backrest (18), a linkage joining the bottom frame (4) and the seat (6) in articulated fashion, a lifting unit (14) operated with compressed water and arranged between the bottom frame (4) and the seat (6), and a control unit for operation of the lifting unit (14). In order to lower the seat in a manner that is physiologically more favourable and safer and, furthermore, to facilitate climbing-in or climbing-out and operation of the bathtub lift (2) the linkage is formed by two front and two rear struts (10) and (12) rotatably connected to the bottom frame (4) and the seat (6), the front struts (10) are arranged vertically and inclined backwards in the upper lifting position of the seat (6) and the rear struts (12) are longer than the front struts (10) and the distance between the upper pivot points (10') and (12') of the front and rear struts (10, 12) is larger than the distance between the lower pivot points (10'') and (12'') of the front and rear struts (10, 12). The seat (6) is designed so as to be rotatable and/or displaceable in the longitudinal direction. <IMAGE>
Patent DE-4303269-C1 (DE)
Title: Main brake cylinder on motor vehicle - has valve part adjoining annulus made from porous material to absorb fluid
Inventor: BARZ UWE
IPC: B60T11/232
Filed: 1993-02-04
Granted: 1994-03-03
Abstract: A main brake cylinder uses a bored and axially grooved piston as engaged by a valve pin ringed by a valve seat and seal. The annular space (54) designed into the valve (40) encloses a permanently free annulus (62) on the seal ring (60) side furthest from the valve seat (38). The valve part adjoining the annulus (62) is made from porous material which can absorb fluid from the annulus (62) and thus ensures that the sealing ring (60) is forced firmly into the annulus when driven onto the valve seat. The valve is made up of a fluid-tight cap (52) which surround the valve head (44) and with the pin (42) serves to confine the annular space (54). Pin and its head are made of sintered material, and the sealing ring comes circular or X-shaped in cross section. USE/ADVANTAGE - Motor vehicles, brake systems. Permanently vacant annulus accepts sealing ring when seated in fluid-tight design affording extended wear life.
Patent DE-4317947-C1 (DE)
Title: Heat-conversion system into mechanical work
Inventor: FASBINDER HANS-GEORG DR RER NA
IPC: F28D17/02
Filed: 1993-05-28
Granted: 1994-06-23
Abstract: The operating medium flows through first and second heat-accumulators, the liberated heat being stored in the first one. The heat for heating the medium is at least partly derived from the second accumulator. Medium flow through the accumulators is reversed at a suitable time interval, so that the first accumulator becomes the second one and vice versa. Storage in the accumulators so takes place that after storage in the first one three-dimensional temp. distribution takes place. This gives a temp. gradient at the hottest area increasing towards the cooler ones.
Patent DE-4320704-C1 (DE)
Title: Assembly with buffer stores for multiple workstations
Inventor: KRUPS PETER
IPC: B23Q7/10
Filed: 1993-06-23
Granted: 1994-07-28
Abstract: The sequence of manual and automated workstations (1a, 1b) is served by a circular track from which workpiece carriers (2) are discharged at the level (5) of three turntables (6a, 6c) rotating in the same direction (7).On each turntable, a guide (9) for the workpiece carriers is provided at the rim (8) with a buffer zone (11) in the centre to which any carrier can be redirected (12) from the entrance to the guide. A flexible upstand (13) deflects the carriers radially towards the rim.
Patent DE-4420481-C1 (DE)
Title: Adjustable car bonnet hinge at windscreen end
Inventor: SCHMID DIETER DIPL ING
IPC: E05D7/04
Filed: 1994-06-11
Granted: 1995-06-29
Abstract: Left and right hinges (12,13) secure the rear end of the bonnet (5) to side panels near the bottom windscreen edge, an access gap being left to them at least in the early stage of assembly. Each hinge has vertical lengthwise halves hinging together via a transverse pin and which are screwed to a vertical face on the panel and a flange at the bonnet underside. The bonnet half (15) is secured to the flange by two or more screws, the first near the hinge axis and with its head towards the middle, so as to be accessible by spanner through the gap between bonnet and windscreen mounting with the former shut. This screw passes through a hole (21) larger than its shank in both the vertical and lengthwise directions. The second screw at the end of the half furthest from the hinge axis passes through an elongated hole parallel to the bonnet surface.
Patent DE-4436946-C1 (DE)
Title: Processing biological household wastes to give, e.g., soil conditioners
Inventor: BOEUF HORST
IPC: C05F17/00
Filed: 1994-10-15
Granted: 1995-06-29
Abstract: Processing biological household wastes comprises: (a) comminuting the wastes to a mushy paste; (b) subjecting the paste to sterilising heat treatment at 70-120  deg C; and (c) setting the pH of the paste to 6.7-7.5 by addn. of additives.
Patent NL-1022585-C1 (NL)
Title: Device is for harvesting vertically growing plants, such as asparagus, from cultivation bed and comprises gathering component displaceable vertically within contour of cylindrical cover, extending with vertical axis
Inventor: WIJNEN PETER HENDRIKUS JOZEF
IPC: A01D45/00
Filed: 2003-02-05
Granted: 2004-08-06
Abstract: The device (1) is for harvesting vertically growing plants, such as asparagus, from a cultivation bed and comprises a gathering component displaceable vertically within the contour of a cylindrical cover (5), extending with a vertical axis. Coupled to the gathering component are operating devices for its displacement vertically. The gathering component has the structure of a screw line (4). The operating devices are formed by a hand grip (6) directed coupled with the gathering component and include a motor for driving the gathering component in rotation. The motor is electrical fed by a battery.
Patent NL-1031337-C1 (NL)
Title: Vessel e.g. ship, anchoring device, has weight part to provide sinking ability to device, weight room connected to weight part, and inlet provided for introducing medium such as gas, into chamber
Inventor: GRUNDLEHNER GERRIT JAN
IPC: B63B21/29
Filed: 2006-03-10
Granted: 2007-09-11
Abstract: The device (1) has a weight part to provide sinking ability to the device, and a weight room connected to the weight part. An air inlet (8) is provided for introducing a medium, such as gas, into a chamber (6), where the inlet is connected to an air compressor (10). The chamber is firmly attached to the weight part, and the inlet is connected to a compressed air source. An independent claim is also included for a method for anchoring a vessel or other floating objects to the bottom of a water body.