baber/WOPTO huggingface dataset:
Patent CA-2709806-A1 (CA)
Inventor: ASKEW BENNY C
IPC: A61K31/437
Filed: 2009-01-20
Abstract: Disclosed are compound according to Formula I: wherein: W1 is CR or N, and W2 is -C-C=C-Ar; or W1 is -C-C.ident.C-Ar, and W2 is CR8 or N; Y is _s., -O-, -NH-, or -NHCH2-; X is N or N+-O';One aspect of the present invention is to provide novel compounds according to Formula 1 that are useful in the treatment of hyperproliferative diseases and inflammatory diseases. Specifically, the compounds of the invention are protein kinase inhibitors. As a result, this invention provides in a first aspect novel compounds according to Formula I, as well as pharmaceutically acceptable salts and pharmaceutically active derivatives thereof, that are useful for the treatment of a subject in need of inhibition of a protein kinase. Values and particular values for the variables in Formula I are provided in the following paragraphs.
Patent CA-2711428-A1 (CA)
Title: Method and constructs for increasing recombinant protein production in plants during dehydration stress
Inventor: LABERGE SERGE
IPC: C12N15/82
Filed: 2009-01-09
Abstract: The present invention provides methods and constructs for increasing recombinant protein production in plants during dehydration stress. The invention includes nucleic acids, inducible expression systems, and methods for using same for increasing recombinant protein production in plants and plant protection.
Patent CA-2713301-A1 (CA)
Inventor: EDWARDS STEVEN L
IPC: D21F5/18
Filed: 2002-01-11
Abstract: An improved process for making sheet from a fibrous furnish includes: depositing the furnish on a foraminous support; compactively dewatering the furnish to form a nascent web; drying the web on a heated cylinder; creping the web therefrom and throughdrying the web to a finished product. The microstructure of the web is controlled so as to facilitate throughdrying. The product exhibits a characteristic throughdrying coefficient of from 4 to 10 when the airflow through the sheet is characterized by a Reynolds Number of less than about 1. The novel products of the invention are characterized by wet springback ratio, hydraulic diameter and an internal bond strength parameter.
Patent CA-2713504-A1 (CA)
Title: Anti-cd79b antibodies and immunoconjugates and methods of use
Inventor: CHEN YVONNE
IPC: C07K16/28
Filed: 2009-01-14
Abstract: The present invention is directed to humanized and conjugated antibodies against CD79b useful for the treatment of hematopoietic tumor in mammals and to methods of using those antibodies for the same.
Patent CA-2713542-A1 (CA)
Title: A process for the coating of metallic surfaces with a lubricant composition containing waxes
Inventor: RAU UWE
IPC: C10M173/02
Filed: 2009-01-26
Abstract: The invention relates to a method for preparing metal workpieces for cold forming by applying a lubricant layer (=coating) either to a metal surface or to a metal surface which has been pre-coated with e.g. a conversion coating. The lubricant layer is formed by contacting the surface with an aqueous lubricant composition which has a content in at least two waxes having distinct properties and a content in organic polymer material, the organic polymer material used predominantly being monomers, oligomers, co-oligomers, polymers or/and copolymers based on ionomer, acrylic acid/methacrylic acid, epoxide, ethylene, polyamide, propylene, styrene, urethane, the ester(s) or/and salt(s) thereof. The invention also relates to the corresponding lubricant composition, to the lubricant layer produced thereof and to its use.
Patent CA-2716379-A1 (CA)
Inventor: MONTANTE JORGE R
IPC: H01H31/02
Filed: 2009-02-19
Abstract: A mounting assembly includes a trunnion body portion (38) and a coupled guiding member (54). The guiding member (54) may be a spring or spring like and may further include a blocking structure (58). The trunnion body portion may include a loop (62).
Patent CA-2717347-A1 (CA)
Title: Web-based multiuser collaboration
Inventor: SALIBA HANI
IPC: G06F15/16
Filed: 2009-01-30
Abstract: Tools and techniques are described for web-based multiuser collaboration.  These tools may provide methods that enable users to collaborate remotely on documents using respective browsers.  These methods may send representations of portions of a given document to the browsers, and associate portions of the documents with particular users. The browsers may receive rep-resentations of commands as provided by the users, and may determine whether to execute the commands at the browser. The methods may also include receiving from the browsers revisions to the portions of the document, and storing these portions of the document in storage areas that are configured for storing content that has changed relatively recently.
Patent CA-2717772-A1 (CA)
Inventor: ALVAREZ-VENEGAS RAUL
IPC: C12N15/82
Filed: 2009-04-06
Abstract: The present invention provides nucleic acid molecules and methods to down-regulate by virus- induced gene si-lencing (VIGS) vernalization genes in winter annuals, specifically the Flowering Locus C (FLC) gene in Brassica napus.  Down-regulation of FLC allows winter annuals to flower without vernalization or with reduced vernalization. This, in turn, provides a shorter breeding cycling and the opportunity for enhanced genetic gain.
Patent CA-2725169-A1 (CA)
Inventor: SHIZUYA HIROAKI
IPC: C12N15/13
Filed: 2009-05-22
Abstract: The present invention describes methods of generating single VL domain antibodies, including chimeric single chain antibodies that comprise of a variable region of a human immunoglobulin .kappa. or .lambda. light chain and a non-human constant region. The non-human constant region is devoid of a first constant domain CH1, and the variable region is devoid of a heavy chain variable domain.
Patent CA-2727584-A1 (CA)
Inventor: YANG LIN
IPC: C11D3/50
Filed: 2009-06-04
Abstract: The invention relates to method of enhancing viscosity of low active liquid cleanser by adding perfumes individual perfume components or mixtures of components.
Patent CA-2729948-A1 (CA)
Title: Tacrolimus for improved treatment of transplant patients
Inventor: GORDON ROBERT D
IPC: A61P37/06
Filed: 2009-07-07
Abstract: An extended release oral dosage form comprising as active substance tacrolimus or a pharmaceutically active ana-logue thereof for a once daily immunosuppressive treatment of a patient in need thereof, preferable a kidney or liver transplant pa-tient The dosage form releases the active substance over an extended period of time It also provides improved pharmacokinetic parameters due to an extended and constant in vivo release including substantial decreased peak concentrations, despite increased bioavailability, substantial extended times for maximal concentration, and higher minimal concentrations when compared with conventional immediate release dosage forms and a recent modified release tacrolimus dosage form
Patent CA-2730068-A1 (CA)
Inventor: CLARKE JAMES
IPC: C12Q1/68
Filed: 2009-07-06
Abstract: The invention relates to a mutant .alpha.-hemolysin (.alpha.-HL) pore which is useful for detecting one or more nucleotides by stochastic sensing The pore is particularly useful for sequencing DNA or RNA A molecular adaptor that allows detection of the nucleotide(s) is covalently attached to the pore The pore is specifically modified to facilitate positioning of the adaptor and may be modified to facilitate covalent attachment
Patent CA-2731621-A1 (CA)
Inventor: DAMNJANOVIC JELENA M
IPC: H04L5/00
Filed: 2009-08-10
Abstract: Aspects describe communicating grant information in a multicarrier wireless communication system. The grant in-formation can be transmitted to mobile devices that have single carrier capability and/or mobile devices that have multicarrier ca-pability. Grant information can be sent in a legacy control region and/or a non-legacy control region.
Patent CA-2733196-A1 (CA)
Inventor: SZYMANSKI MATTHEW ALAN
IPC: A47D15/00
Filed: 2011-03-03
Abstract: An infant support structure includes a frame, a seat portion rotatably coupled to the frame so that the seat portion is movably coupled to the frame, an engagement member coupled to the seat portion, and a lock bar pivotally coupled to the lower portion of the frame, the lock bar movable between a first position disengaged from the engagement member thereby permitting swinging motion of the seat portion, and a second position engaging the engagement member and inhibiting swinging motion of the seat portion.
Patent CA-2734969-A1 (CA)
Title: Improvements for rapid prototyping apparatus
Inventor: PETERSEN MICHAEL A
IPC: B29C67/00
Filed: 2009-10-09
Abstract: The present invention relates to improvements relating to a rapid prototyping apparatus for the manufacturing of three-dimensional objects by additive treatment of cross-sections. The improvements relates to distances, a protective window, and a collision-preventing detection system.
Patent CA-2735522-A1 (CA)
Inventor: REFAELI YOSEF
IPC: C07K14/82
Filed: 2009-08-28
Abstract: Disclosed herein are methods of modulation of the viability of a cell. Further disclosed herein are methods of mod-ulating an immune response. Further disclosed herein are methods of identifying agents capable of modulation of the viability of a cell or an immune response. Further disclosed herein are agents and compositions capable of modulation of the viability of a cell or an immune response.
Patent CA-2738535-A1 (CA)
Inventor: NEEL THOMAS C
IPC: E02D29/02
Filed: 2005-08-12
Abstract: A precast concrete retaining wall construction element for retaining a soil mass in a railway installation or the like includes an upstanding solid face panel having the shape of a hexahedron where a rectangular front wall and an integral stem. The front wall defines an area of between about 18.75 and 75 square feet and wherein the ratio of the width of the face panel to its height is between about 0.75 to about 3Ø A reinforced element including an upward extension, an improved shear key, and stacked arrangement are also disclosed.
Patent CA-2741373-A1 (CA)
Inventor: GUO PEIXUAN
IPC: G01N33/68
Filed: 2009-10-30
Abstract: Compositions and methods are disclosed that exploit the unprecedented modification of double-stranded DNA  virus DNA-packaging motor protein connector polypeptides to render them capable of stable incorporation into lipid membranes as a self-assembled homodocamer that forms an aperture through which conductance can occur when an electrical potential is applied across the membrane. The aperture permits use of the modified protein as a biosensor, for dsDNA sequencing, SNP detection and highly sensitive affinity capture and fingerprinting of analytes, and also finds use in electropotential-driven solute translocation, such as for liposomal loading to form therapeutic nanoparticles (e.g., gene delivery) and bioreactors, and for other uses.
Patent CA-2742324-A1 (CA)
Title: Methods for assessing rna patterns
Inventor: KLASS MICHAEL
IPC: C12Q1/68
Filed: 2009-10-30
Abstract: Methods and compositions for the characterizing of cancers by assessing RNA  levels, such as determining an RNA  pattern, are provided herein. The diagnosis, prognosis, monitoring and treatment or a cancer can be determined by detecting one or more RNAs, such as microRNAs.
Patent CA-2744918-A1 (CA)
Inventor: HILSABECK DOUGLAS A
IPC: A01F25/20
Filed: 2009-06-10
Abstract: A grain bag handling assembly for a grain bag unloading apparatus has an auger assembly with an input end which is inserted into a mouth of an elongated grain bag and a remote output end. The grain bag handling assembly has a bag feeding assembly that has a feed mouth, guides to guide the grain bag into the feed mouth, a bag driver for applying a force to pull the grain bag through the feed mouth and at least two knives which cut the grain bag into two more separate portions.
Patent CA-2745220-A1 (CA)
Inventor: YOSHIKUNI YASUO
IPC: C12P5/00
Filed: 2009-12-11
Abstract: Methods, enzymes, recombinant microorganism, and microbial systems are provided for converting suitable monosaccharides or oligosaccharides, such as those derived from biomass, as well as various aldehydes and/or ketones, into commodity chemicals, such as biofuels. Commodity chemicals produced by the methods described herein are also provided.  Commodity chemical enriched, refinery-produced petroleum products are also provided, as well as methods for producing the same.
Patent CA-2745674-A1 (CA)
Inventor: WOODLEY MICHAEL
IPC: H04W24/06
Filed: 2009-12-21
Abstract: A radio frequency radio (RF) transceiver that defines scheduling logic for generating transmission schedules for orthogonal frequency-division multiple access (OFDMA) RF transmissions from the RF transceiver, wherein the scheduling logic specifies at least one of a modulation type, a code rate, a sub-channel, and a sub-carrier for a plurality of symbols to be transmitted in a communication signal sub-frame. A processor generates outgoing data bits and outgoing test data bits for transmission from the RF transceiver as OFDMA transmission signals and OFDMA test data transmission signals, respectively, according to the transmission schedules to create loading within at least a portion of a cellular service area that corresponds with a test- loading value. The amount of the additional required loading is the difference between the test- loading value and an actual loading value.
Patent CA-2746115-A1 (CA)
Title: Produits medicamenteux utilisables dans le cadre du traitement de troubles de la coagulation sanguine et contenant un concentre de facteur xia exempt de thrombine
Inventor: EIBL JOHANN
IPC: A61K38/36
Filed: 2010-09-16
Abstract: La présente invention concerne un concentré de facteur XIa ou un concentré de facteurs de coagulation, exempt de thrombine et sans danger d'un point de vue viral, contenant du facteur XIa en tant que principe actif pharmaceutique. Ledit concentré peut être obtenu par fractionnement plasmatique ou sérique ou, encore, par génie génétique et peut être utilisé dans le cadre du traitement de troubles de la coagulation associés à une production de thrombine insuffisante et/ou différée.
Patent CA-2748309-A1 (CA)
Inventor: SYMONS GARY MARK
IPC: G06F3/048
Filed: 2009-12-23
Abstract: An editing method includes detecting a se-lection of first and second clip portions of a source media depiction, generating corresponding first and second block icons and snapping hands-free the first and second block icons across the screen to a linear queue so that the blocks are snugly adjacent, detecting a move of the first or second block icon relative to one another substantially along the queue, and if the first or second block icon overlaps the other by substantially one half of the other block icon, re-versing displayed positions m the queue of the first and second block icons
Patent CA-2749026-A1 (CA)
Inventor: QUADRI ARSHAD
IPC: A61F2/24
Filed: 2009-09-29
Abstract: A heart valve (600) includes a valve body (330) made of a flexible material such as pericardium. The valve body is made of two layers of material, an outer lay-er, and an inner layer that defines a plurality of leaflets.  The leaflets of the inner layer are attached to the outer lay-er. In some embodiments the valve body is made by cut-ting a single piece of flat source tissue, folding the cut tis-sue and forming it into a tubular pattern having the inner and outer layers. The multi-layer valve body can be mounted on a stent (500) for delivery within a patient's heart.
Patent CA-2749241-A1 (CA)
Inventor: KNOBLOCK KENNETH
IPC: C08G18/64
Filed: 2010-01-08
Abstract: The invention relates to a foamed isocyanate -based polymer derived from a reaction mixture comprising an isocyanate, an active hydrogen-containing compound, a blowing agent and a highly branched polysaccharide which is derivatized with at least two esters of different length. Further the invention relates to a mix and a process for the production of isocyanatebased polymer. The mix for the production of a foamed isocyanate-based polymer comprises a mixture of the derivatized polysaccharide of the invention and an active hydrogen-containing compound. The process for producing a foamed isocyanate-based polymer comprises the steps of: contacting an isocyanate, an active hydrogen-containing compound, the derivatized highly branched polysaccharide of the invention and a blowing agent to form a reaction mixture and expanding the reaction mixture to produce the foamed isocyanate-based polymer. The derivatized highly branched polysaccharide of the invention has an active hydrogen functionality of less than 15 and comprises randomly bonded glucopyranose units, having an average number of 10-100 glucose residues.
Patent CA-2750538-A1 (CA)
Title: Device and method for detection of humidity-compromised urine test strips
Inventor: ZIMMERLE CHRIS T
IPC: C12Q1/44
Filed: 2010-01-14
Abstract: The timing of the reaction of moisture-sensitive reagents for detecting the presence of analytes, e.g. leukocytes in urine samples, is used to detect when the reagents have been compromised by excess humidity. The ratio of light reflectance at wavelengths characteristic of the products of reaction between the reagents and the analyte and an infra-red reference dye is measured at two preset times after a urine sample has been applied to a test strip and used to determine whether the reagents have been compromised by excessive humidity. The presence of unusually dark samples is determined from the reflected light at 470 and 625 nm in order to confirm that the test strips are humidity-compromised.
Patent CA-2750899-A1 (CA)
Inventor: LEE YOUNG GYU
IPC: A61J3/00
Filed: 2010-02-02
Abstract: The present invention provides an apparatus for controlling an administration rate of medical fluid. The apparatus is configured such that medical fluid supplied into a single inlet tube is divided by a plurality of capillary tubes into several streams of medical fluid which have different flow rates, and the tubes through which the streams of medical fluid flow are switched by a multi-valve to select one of various flow pathways. Therefore, the flow rate of medical fluid can be quantitatively selected so that an appropriate amount of medical fluid is administered to an administration target, such as a patient, along the selected flow pathway.
Patent CA-2753727-A1 (CA)
Inventor: GRENZ ROBERT LEE
IPC: G01N1/28
Filed: 2011-09-28
Abstract: A dried biological fluid spot punch device includes a tube, a frit, and a filter disposed on the frit. The tube includes a main section and a distal section adjoining the main section. The main section includes a proximal tube end circumscribing a proximal tube opening, and the distal section includes a distal tube end circumscribing a distal tube opening. The distal section further includes a distal tube having a tapered inside diameter that reduces from the main section to the distal tube opening. The frit is disposed in the distal section at a distance from the distal tube opening and fixed in position by frictional contact with the distal tube wall. The punch device may also include a punching tool. The punching tool may include a body engaging the tube at the proximal tube end and an ejection mechanism configured for disengaging the body from the tube.
Patent CA-2756928-A1 (CA)
Title: Rotatable wedge tile spacer having a curved body
Inventor: BURNS JASON W
IPC: E04F21/00
Filed: 2009-10-13
Abstract: A rotatable wedge tile spacer (30, 65) to be removably positioned in a gap (58) between adjacent upper and lower tiles (50 and 52) that are being bonded one above the other to a vertical surface (i.e., a wall).  The tile spacer (30, 65) includes a curved (i.e., circular) body (32, 67) having a thin tip (36, 69) at one end and a thick tail (38, 70) at the opposite end. The height of the circular body (32, 67) increases along a tile-supporting top surface (34, 74) thereof that runs from the thin tip to the thick tail. With the tile spacer (30, 65) seated upon the lower tile (52), the circular body (32, 67) is rotated continuously around its longitudinal axis (40, 76) until the tile- supporting top surface (34, 74) engages the upper tile (50). Accordingly, the circular body (32, 67) of the rotatable wedge tile spacer (30, 65) will fill the gap (58) and thereby prevent the upper tile from moving through the gap towards the lower tile during the bonding process.
Patent CA-2757062-A1 (CA)
Inventor: ADAMSON GEORGE W
IPC: C25B1/26
Filed: 2010-03-26
Abstract: The present invention provides novel cathodes having a reduced resistivity and other improved electrical properties. Furthermore, this invention also presents methods of manufacturing novel electrochemical cells and novel cathodes. These novel cathodes comprise a silver material that is doped with a Irivalent species.
Patent CA-2759413-A1 (CA)
Title: Coating compositions and coatings produced from them and featuring high scratch resistance in association with good results in the erichsen cupping test and good antistonechip properties
Inventor: GROENEWOLT MATTHIJS
IPC: C08G18/62
Filed: 2010-03-08
Abstract: The present invention relates to coating agents comprising (A) at least one polyacrylate comprising hydroxyl groups and/or at least one polymethacrylate comprising hydroxyl groups, and (B) at least one compound (B) comprising isocyanate groups having at least one structural unit (I) of the formula (I) -NR-(X-SiR"x(OR')3-x) (I), and at least one structural unit (II) of the formula (II) -N(X-SiR"x(OR')3-x)n(X'-SiR"y(OR')3-y)m (II), characterized in that (i) the polyacrylate comprising hydroxyl groups and/or the polymethacrylate comprising hydroxyl groups comprise a glass transition temperature of less than 10°C, (ii) the compound (B) comprising isocyanate groups comprises more than 10 to 90 mol %  of at least one structural unit of the formula (I) and 10 to less than 90 mol % of at least one structural unit of the formula (II), each relative to the entirety of the structural units (I) and (II), and (iii) 10 to 60 mol % of the isocyanate groups of the di- and/or polyisocyanate base body of the compound (B), have been converted to the structural units of the formulas (I) and (II). The present invention further relates to a multistage coating method using said coating agent and to the use of the coating agent as a clear varnish, or to the use of the coating method for series painting of automobiles, painting of automobile accessories, and repair painting of automobiles.
Patent CA-2759842-A1 (CA)
Inventor: MEEKS JEFFREY A
IPC: A63B71/00
Filed: 2010-04-23
Abstract: A fitness product utilizes a projection display assembly.  The assembly comprises an image source and a projection surface. The image source can comprise a light source and an image creator, where the light source shines through the image creator. The image produced by the image creator can be focused with a lens and can be redirected with a reflector.    The projected image can be viewed on the projection surface and the projection surface can comprise a touchscreen surface. The assembly provides a substantially sealed and protected image source and a projection surface that can serve to control the fitness product through interactions with the projected images.
Patent CA-2762595-A1 (CA)
Inventor: EINICKE GARRY ALLAN
IPC: H04B10/43
Filed: 2010-05-28
Abstract: A communication system including: a first communication device located in a first zone; a second communication device located in a second zone for generating an optical carrier signal; and at least one optical fibre connected to the first communication device for supplying power for operation of the first communication device and for supplying the optical carrier signal from said second zone, wherein the first communication device includes: a user interface for inputting information; and an optical modulator for modulating the optical carrier signal to include information input with said user interface and forwarding the modulated signal via the at least one optical fibre to the second communication device.