baber/WOPTO huggingface dataset:
Patent CZ-297797-B6 (CZ)
Title: Tricyclic diazepine derivatives, process of their preparation and pharmaceutical composition containing thereof
Inventor: ALBRIGHT JAY DONALD
IPC: C07D471/04
Filed: 1996-01-16
Abstract: In the present invention, there are disclosed tricyclic diazepine derivatives of the general formula I, which exhibit vasopressin antagonist activity and can be therefore used in the form of a pharmaceutical composition in treating diseases caused by very high concentration of vasopressin, such as congestive heart failure, nephrotic syndrome, hyponatremia and the like.
Patent CZ-285826-B6 (CZ)
Inventor: BOGG WALTER
IPC: G02B6/36
Filed: 1995-04-26
Abstract: Karbice k uložení světlovodičů cedoucích k alespoň jednomu spoji vykazuje více vstupů (3) pro světlovodiče k vzájemnému spojení. Do každého vstupu (3) jsou vsaditelná uchycení (5) pro odlehčení v tahu pro světlovodiče. V krabici (1) jsou vytvořeny úložné prostory (40) a záchytné prostory (50') pro světlovodiče vedoucí ke spoji. Záchytné prostory (50') jsou pro světlovodiče k vzájemnému spojení dostupné shora skrz labyrint (50) pro vlákna, zahrnující tři jazýčky (51, 52) uspořádané vedle sebe a vzájemně se přesahující, umístěné různě vysoko. Úložné prostory (40) jsou na straně ležící naproti základní desce (2) krabice (1) uzavřeny jazýčky (41) a těsně uzavíratelné odnímatelnými západkami (42). na vnějším okraji krabice (1) jsou na foliových závěsech (21) vytvořeny západkovité úchytky (20), které slouží ke spojení krabic (1) položených nad sebou.
ŕ
Patent CZ-294364-B6 (CZ)
Title: Coupled axle for motor vehicles
Inventor: GLASER KLAUS
IPC: B60G21/05
Filed: 1998-11-13
Abstract: The present invention relates to a coupled axle for motor vehicles comprising two tubular longitudinal control arms (3) connected through a torsion section (2)¿having a V-shaped or U-shaped cross-section, wherein reinforcing sheet metal pieces (12) are mounted in the transition areas between the torsion section (2) and the longitudinal control arms (3) for increasing the bending stiffness. The invention is characterized in that the ends (8) of the torsion section (2) have a configuration which is adapted to the outer contour of the longitudinal control arms (3) and the apex portions (9) located at the ends extend to the upper sides (10) of the longitudinal control arms (3), wherein the reinforcing sheet metal pieces (12) are each welded with a leg  (13) thereof to the torsion section (2) at the apex portion (9) of the torsion section¿(2)  and with another leg (14) to the length portion (15) of the longitudinal control arm (3) on the side of a wheel carrier, wherein the reinforcing sheet metal pieces (12) are arranged so as to be inclined downwardly from the torsion section (2)  toward the end (4) of the longitudinal control arm (3) on the side of the wheel carrier (5), and wherein the reinforcing sheet metal pieces (12) engage with end faces thereof around portions of a wheel carrier (5) and are connected thereto.
Patent CZ-299816-B6 (CZ)
Title: Isonitrile compounds for preparation of polymers containing nucleic bases as side groups
Inventor: DOEMLING ALEXANDER
IPC: C07B61/00
Filed: 1998-05-14
Abstract: The present invention relates to a process for preparing polymers having nucleic bases as side groups by means of multicomponent reactions, specially the Ugi reaction. By virtue of the multicomponent nature of production, the properties of the polymers can be modified to a greater degree than before and can be adapted to meet the requirements for use as antisense or antigen therapeutic agents or diagnostic reagents.
Patent SK-283649-B6 (SK)
Title: Novel method for isomerising the 10-methyl radical of erythromycin derivatives
Inventor: BENEDETTI YANNICK
IPC: C07H17/08
Filed: 1997-05-13
Abstract: An isomerisation method wherein a compound of formula (IA), wherein X and y together form a 3-oxo radical, or X is a hydrogen atom and Y is either a radical (a), where R2 is OH or O-acyl, or an O-alkyl or NH2 radical; R1 is a hydrogen atom or a methyl radical; Z is hydrogen or an acyl radical; and R is a hydrogen atom, an NH2 radical or a (CH2)nAr, NH(CH2)nAr or N=CH(CH2)nAr radical, in the form of a 10'alpha' isomer or a mixture of 10'alpha' and 10'beta' isomers, is exposed to a basic agent to give the corresponding compound of formula (I) in which the 10-methyl radical is in the 'beta' position.
Patent SK-278299-B6 (SK)
Title: The auxiliary preparation for welding
Inventor: POLIEVKA MILAN
IPC: B23K35/38
Filed: 1990-11-26
Abstract: The auxiliary preparation used for welding purposes prevents the adhesion of the sprays to surface of the welded metal. This preparation consists of at least one compound related to diester of polyethylene-glycol 1 up to 95 parts of weight with molar weight of 300 up to 3000 g/mol, the suitable compound are polyethylene glycol maleate, ethylene glycol monobuthylethers molar weight of 100 up to 170 g/mol, polyvinyl alcohol, copolymer of propylene oxide and ethylene oxide, together with a surface- -active agent max. 50 parts of weight and/or auxiliary additives and water, actually 1 up to 1000 parts of weight. The emulsifying agent, ethylene diamine diester, triethanol amine, silicon oil and sodium hypophosphite is used as the suitable additives for the above mentioned purposes.
Patent CZ-302650-B6 (CZ)
Title: Self-loading firearm with locked breech mechanism
Inventor: CERVINKA PETER
IPC: F41A3/12
Filed: 2005-12-21
Abstract: In the present invention, there is disclosed a self-loading firearm consisting of main parts ?, such as a body (1) with firing mechanism a barrel (7), a breechblock (10) and a return spring (14), whereby the body (1) is provided in its upper side with a bed (2) for placing therein the barrel (7). The return spring (14) is arranged in a bore below this bed (2). The body (1) is provided with a front S-shaped slot (3), in which, there is arranged a front pin (12). In the backside of the body (1), there is performed a rear L-shaped slot (4) intended for accommodation of a rear pin (15). The front pin (12) and the rear pin (15) form parts of the breechblock (10) being provided in its rear portion with a striker (16) with an igniter and a spring. The breechblock (10) has inside in its front portion a recess (11) serving for engagement of a barrel (7) claw (9) provided in the upper front portion thereof wherein in the lower front portion, the barrel (7) is provided with a stop (8). In said body (1) bore, the return spring (14) bears along with a washer (13) against the front pin (12) and a forefront (17) is attached to the front part of body (1). The lift of the breechblock (10) front portion is defined by the shape of the front S-shaped slot (3) in vertical plane passing through the barrel (7) axis.
Patent CZ-309367-B6 (CZ)
Title: The process of designing and manufacturing a prosthetic bed
Inventor: ROSICKÝ JIŘÍ
IPC: G06F30/20
Filed: 2019-08-20
Abstract: The solution is designing and manufacturing a 3D printed prosthetic bed (3) including obtaining the physical data of the patient with an amputated stump, obtaining or creating a digital representation of the modified surface of the amputated stump, creating a structural design of the 3D printed prosthetic bed (3) sending the structural design data of the prosthetic bed (3) to the 3D printer and making the prosthetic bed (3) by 3D printing. Creating the structural design of the 3D printed prosthetic bed (3) includes determining the density of the 3D printed reinforcing structures in the volume of the 3D printed prosthetic bed (3) between the shaped surface for placing the connecting part (10) of the liner and the distal surface for fixing the connecting adapter (4) of the bed directly proportionally depending on at least one of the data from the set containing at least the weight, the level of activity of the patient, the length of the amputation stump, the length of the prosthesis (6), the size of the prosthetic foot (8), and the angle between the axis of the stump and the axis of the prosthesis (6).
Patent CZ-288303-B6 (CZ)
Title: Analysis method of light spectral distribution and apparatus for making the same
Inventor: VECER JAROSLAV
IPC: G01J3/28
Filed: 2000-03-20
Abstract: The proposed method employs physical phenomenon of optical dispersion rotation for determining light spectral characteristics. Polychromatic linearly polarized radiation passes through a medium, which bends polarization plane of spectral components thereof in dependence on wavelength. After subsequent passage through an analyzing polarizer a dependence of light intensity S({phi})    at the angle {phi} that is included by the analyzing polarizer with the analyzed light polarization plane is measured. The light intensity is in mathematical relationship with the analyzed radiation spectrum I({lambda}) ({lambda} denotes the wavelength) and makes it so possible to determine spectral characteristics of the analyzed radiation. In apparatuses operating on the above-described principle a collimated polarized beam of the analyzed radiation passes first through an optical element exhibiting dispersion of optical rotation i.e. a rotator (4), further through an analyzing polarizer (5) and after representation it is detected by a suitable detector (7) that is capable to measure the function S({phi}) in dependence on the angle of the polarizer angular displacement, whereby from this function the spectrum parameters I({lambda}) are subsequently determined.
Patent CZ-295979-B6 (CZ)
Title: Device to clamp a workpiece
Inventor: LUSCHER MARCEL
IPC: B23Q3/18
Filed: 2000-07-12
Abstract: The present invention relates to a device to clamp a workpiece comprising a chuck (1) that can be fastened within a working region of a machine tool, a workpiece carrier (25) that can be fastened and clamped in the chuck (1), further positioning elements formed by first positioning means (22, 23) disposed on the chuck (1) and second positioning means (30, 29) arranged on the workpiece carrier (25), which means interact in pairs and position workpiece carrier (25) in three coordinate axes (X, Y, Z) extending perpendicularly to each other and in a correct angle relative to the chuck (1), and further a clamping mechanism (12, 14, 18, 28) the clamping force of which holds down the workpiece carrier (25) in the chuck (1) in position performed by the positioning means. Said first positioning means (22) and said second positioning means (30) are arranged on a circle. Said clamping mechanism includes clamping elements, axial component clamping forces of which act at least approximately on or outside an imaginary cylindrical continuous surface (MF) being parallel to the coordinate axis (Z) and intersection said first positioning means (22, 23) and said second positioning means (29, 30).
Patent CZ-302328-B6 (CZ)
Title: Pharmaceutical composition
Inventor: BOZUNG KARL-HEINZ
IPC: A61P11/00
Filed: 2000-05-03
Abstract: This invention introduces a new pharmaceutical composition, which contains a long-term effect anticholinergic agent and a long-term effect {beta}-mimetic agent, optionally in the form of their racemates, enantiomers, diastereomers and mixtures thereof, whereas the anticholinergic agent is tiotropium bromide and the long-term effect {beta}-mimetic agent is formoterol or salmeterol, optionally in the form of their pharmaceutically acceptable acid addition salts.
Patent CZ-302537-B6 (CZ)
Title: Apparatus for producing heating gas from carbon-containing, particularly biogenic feed materials
Inventor: KARL JUERGEN
IPC: B01J8/26
Filed: 2000-06-09
Abstract: In the present invention, there is disclosed an apparatus for producing heating gas from carbonaceous, especially biogenic feed materials by allothermic steam gasification, the apparatus comprising: a pressure-supercharged fluidized-bed gasification chamber (10) with a pressure-tight lock (2) for supplying the feed materials (3) that are to be gasified, a filter chamber (17) connected to the fluidized-bed gasification chamber (10) via a connecting channel (16, 16?), an external heat source (4), and a heat-pipe arrangement (22) that takes up heat from the external heat source (4) and gives it off to a gasification bed in the fluidized-bed gasification chamber (10).
Patent CZ-294751-B6 (CZ)
Title: Medicament for the treatment or prevention of coronary graft vasospasm
Inventor: LEHTONEN LASSE
IPC: A61K31/50
Filed: 2000-06-29
Abstract: In the present invention, there is disclosed the use of (-)-[[4-(1,4,5,6-tetrahydro-4-metyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]propane dinitrile or a pharmaceutically acceptable salt thereof for the preparation or a medicament that is useful in the treatment or prevention of coronary graft vasospasm.
Patent CZ-304739-B6 (CZ)
Title: Fabric-cutting device for sewing machine
Inventor: MURAI KENJI
IPC: D05B37/04
Filed: 2000-12-12
Abstract: In the present invention, there is disclosed a fabric cutting device (1) for sewing machine (100) comprising a fabric-cutting knife (5) to cut through a sewed object (200) for making a buttonhole having an eyelet portion (202) and a linear portion (203). The fabric-cutting knife (5) has an eyelet knife portion (54) for making a buttonhole eyelet portion (202) and a linear knife portion (55) for making a buttonhole linear portion (203) wherein said eyelet knife portion (54) and said linear knife portion (55) are arranged for making the an eyelet buttonhole (201) portion on the sewed object (200). The linear knife portion (55) is arranged for making a buttonhole linear portion (203) on the sewed object (200) without interference of the eyelet knife portion (54) in the sewed object (200), provided the sewed object (200) is cut through by means of the fabric-cutting knife (5). A portion for non cutting the sewed object (200) is arranged between said eyelet knife portion (54) and said linear knife portion (55) of the fabric-cutting knife (5).
Patent SK-288113-B6 (SK)
Title: Aqueous, sterile, ready-to-use pharmaceutical composition comprising esmolol hydrochloride and method for its preparation
Inventor: LIU JIE
IPC: A61K9/08
Filed: 2002-01-02
Abstract: It is described an aqueous, sterile, ready-to-use pharmaceutical composition suitable for parenteral administration by infusion for the treatment of cardiac conditions, being packaged in a sealed container, having a pH between 3.5 and 6.5 and comprising: a) 0.1 to 100 mg/ml methyl-3- [4-(2-hydroxy-3- isopropylamino)propoxy] phenylpropionate hydrochloride (esmolol hydrochloride) ; b) 0.01 to 0.5 M buffering agent; and c) 1 to 100 mg/ml osmotic-adjusting agent selected from at least one of sodium chloride, dextrose, sodium bicarbonate, calcium chloride, potassium chloride, sodium lactate, Ringer's solution and lactated Ringer's solution; a method for preparing this composition.
Patent BR-PI0315735-B8 (BR)
Inventor: BELKOURA IKRAM ELYAZIDI
IPC: G01N33/574
Filed: 2003-10-28
Abstract: In vitro diagnosis of breast cancer comprises detecting nerve growth factor (NGF) in a patient sample. ACTIVITY : Cytostatic. MECHANISM OF ACTION : Inhibition of NGF. MCF-7 breast cancer cells were grown to 40% confluence then incubated in presence of K-252a, a known inhibitor of NGF. After an unspecified time, the number of tumor cells was measured; it was about 0.36 million (per 35 mm disk) in absence of inhibitor but only 0.27 and 0.21 million at inhibitor concentrations 5 and 10 nM, respectively.
Patent BR-PI0318268-B8 (BR)
Inventor: FRANZ FISCHER
IPC: A46D1/00
Filed: 2003-04-22
Abstract: The toothbrush head (3) has brush support (4) having a pattern of round tipped bristles (6) and a second limited distribution (7) of pointed bristles (5) having a longer length to penetrate between the teeth during angular and rotational activity of the head.
Patent CH-700068-B8 (CH)
Title: Verfahren zur Reinigung einer Dibenzoxepin-Verbindung.
Inventor: KATSURA TADASHI
IPC: C07D313/02
Filed: 2008-10-02
Abstract: (Z)-11-(3-Dimethylaminopropyliden)-6,11-di-hydrodibenzo [b,e]oxepin-2-essigsäure oder ein Säureadditionssalz davon, die als medizinische Zusätze nützlich sind, können effizient und gewerblich vorteilhaft mittels eines Verfahrens zur Reinigung von (Z)-11-(3-Dimethylaminopropyliden)-6,11-dihydrodibenzo[b,e]oxepin-2-essigsäure oder einem Säureadditionssalz davon hergestellt werden, welches Verfahren das Auflösen von (Z)-11-(3-Dimethylaminopropyliden)-6,11-dihydrodibenzo[b,e]oxepin-2-essigsäure, dargestellt durch die Formel [I]: oder einem Säureadditionssalz davon in einem aus Wasser und einem Keton-Lösungsmittel gemischten Lösungsmittel und das Fällen von Kristallen aus der erhaltenen Lösung umfasst.
Patent EP-1170748-B8 (EP)
Inventor: PIJANOWSKI STEFAN ALEXANDER
IPC: G11B33/04
Filed: 1997-04-11
Granted: 2009-12-23
Abstract: Apparatus for holding a compact disk having a central hole, the apparatus comprising: a base portion; a disk engaging and release mechanism extending from the base portion for releasably engaging the central hole of a disk comprising three equi-angularly spaced arms each resiliently cantilevered from the base portion, the inner ends of the arms together forming a button-like member for releasably engaging the central hole of a disk; and support means in the form of a raised surface extending around the disk-engaging means and arranged to support the periphery of a disk mounted on the apparatus during operation of the disk-engaging and release mechanism. <IMAGE>
Patent EP-2093083-B8 (EP)
Inventor: DIETRICH GUNNAR
IPC: B60H1/00
Filed: 2007-03-16
Granted: 2010-12-22
Abstract: The system has an external heat exchanger (2), an internal heat exchanger (5), an expansion chamber (4) and a cooling medium circuit with a compressor, where the internal heat exchanger is separated in an air stream direction. Two partial heat exchangers (51) of the internal heat exchanger are utilized as two cooling medium gas coolers for heating supply air by switching units during maximal heat requirement. Two partial heat exchangers (52) of the internal heat exchanger for cooling the supply air are operated as cooling medium evaporators.
Patent BR-PI0514411-B8 (BR)
Title: formulação, e, método de produzir uma formulação
Inventor: DANIEL DIX
IPC: C07K14/545
Filed: 2005-08-17
Abstract: formulação, e, método de produzir uma formulação. proporciona-se formulações de um antagonista de interleucina-1 (il-1) incluindo uma formulação pré-liofilizada, um formulação liofilizada reconstituída, e uma formulação líquida estável. de preferência, o antagonista de il-1 é uma captação de il-1 constituída de um dímero de duas proteínas de fusão apresentado uma seqüência de aminoácidos selecionada do grupo que consiste de seq id no: 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, e 26. da forma mais preferível, a proteína de fusão tem a seqüência da seq id no: 10.
Patent BR-PI0806273-B8 (BR)
Title: atuador para inalador atuado por respiração
Inventor: HENRIK HOUGAARD VILSTRUP
IPC: A61M15/00
Filed: 2008-01-02
Abstract: atuador para inalador atuado por respiração. a presente invenção refere-se a um atuador para inalador atuado por respiração (bai) que compreende: um elemento de carregamento capaz de ser carregado com uma força de atuação, um mecanismo de gatilho atuado por respiração, arranjado para equilibrar a força de atuação do elemento de recarregamento e para disparar o atuador liberando a força de atuação do elemento de carregamento em resposta a uma respiração de inalação, e dispositivo de travamento de atuação móvel entre uma posição travada na qual ele alivia a força de atuação do mecanismo de gatilho ajustando o mecanismo de gatilho em uma posição neutra, e uma posição armada na qual o mecanismo de gatilho é ajustado em uma posição armada.
Patent BR-PI0918069-B8 (BR)
Inventor: BENJAMIN WENZEL
IPC: A61F13/15
Filed: 2009-08-27
Abstract: An incontinence article (2) in the form of briefs has a front stomach portion (4) and a rear back portion (6), which are connected to one another at lateral seam regions (14) on both sides. A crotch portion (8) has an absorption pad (7) and extends in a longitudinal direction (9). A topsheet material (84) or a topsheet (84) and a backsheet material (62) form a transverse overhang (66a,66b) extending outside longitudinal borders (46) of the absorption pad (7). The overhang (66a,66b) has a reinforcing means (200) in a region (204) bridging the respective longitudinal border (46) of the absorption pad (7). The reinforcing means (200) comprises or consists of a reinforcing coating (202 and is disposed on the inner face (85) of the topsheet material (84).
Patent AU-2012205166-B8 (AU)
Title: Inhibitors of Bruton's tyrosine kinase
Inventor: VERNER ERIK
IPC: A61P29/00
Filed: 2012-07-16
Granted: 2013-06-27
Abstract: INHIBITORS OF BRUTON'S TYROSINE KINASE Abstract Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions. (64408731 ):KZA
Patent BR-112014016322-B8 (BR)
Title: processo para a preparação de 1-[2-(2,4-dimetil-fenilsulfanil)-fenil]-piperazina
Inventor: KIM LASSE CHRISTENSEN
IPC: C07D295/096
Filed: 2012-12-20
Abstract: processo para a preparação de 1-[2-(2,4-dimetil fenilsulfanil)-fenil]-piperazina. é revelado um processo para a preparação de 1-[2-(2,4-dimetil-fenilsulfanil)-fenil]-piperazina e sais farmaceuticamente aceitáveis que envolve fazer reagir compostos da fórmula ii, iii, iv, sob catálise com pd e na presença de ligantes fosfina, para dar origem ao composto i.
Patent BR-122012012032-B8 (BR)
Title: usos de inibidores de cinase úteis para preparação de composições farmacêuticas utilizáveis no tratamento de doenças proliferativas
Inventor: DANIEL L FLYNN
IPC: A61K39/395
Filed: 2007-09-13
Abstract: usos de inibidores de cinase úteis para preparação de composições farmacêuticas utilizáveis no tratamento de doenças proliferativas. a presente invenção se refere ao uso de novos inibidores de cinase e compostos moduladores na preparação de composições farmacêuticas utilizáveis no tratamento de várias doenças. mais particularmente, a invenção se refere a tais compostos, adutos de composto/cinase, métodos de tratar doenças, e métodos de síntese dos compostos. preferivelmente, os compostos são úteis para a modulação de atividdae de cinase de raf cinases e polimorfos de doença destes. os compostos da presente invenção encontram utilidade no tratamento de cânceres mamíferos e especialmente cânceres humanos incluindo, porém não limitados a melanoma maligno, câncer colorretal, câncer de ovário, carcinoma de tireóide papilar, câncer de pulmão de célula não pequena, e mesotelioma. compostos da presente invenção também encontram utilidade no tratamento de artrite reumatóide e retinopatia incluindo neuropatia retinal diabética e degeneração macular
Patent DE-3149717-C1 (DE)
Title: Angular drilling gauge for carrying out surgery on bones
Inventor: DAWIDOWSKI GERHARD
IPC: A61B17/17
Filed: 1981-12-15
Granted: 1983-07-28
Abstract: The invention relates to an angular drilling gauge consisting of a hand grip and a guide sleeve, which has a bearing surface at the proximal end. In order to drill two holes converging at an angle, a further guide sleeve is arranged at an angle to the guide sleeve. The guide sleeves are attached to the two ends of a cross-piece fixed to the proximal end of the hand grip.