baber/WOPTO huggingface dataset:
Patent DO-P2022000115-A (DO)
Title: Tetrahidrofuranos sustituidos como moduladores de canales de sodio
Inventor: STEPHEN ANDREW THOMSON
IPC: C07D405/14
Filed: 2022-06-03
Abstract: Se proporcionan compuestos y sus sales farmacéuticamente aceptables, de utilidad como inhibidores de canales de sodio. También se proporcionan composiciones farmacéuticas que comprenden los compuestos o sales farmacéuticamente aceptables y métodos de uso de los compuestos, sales farmacéuticamente aceptables y composiciones farmacéuticas en el tratamiento de diversos trastornos, incluyendo el dolor.
Patent DO-P2022000251-A (DO)
Title: Conjugado anticuerpo-fármaco, método de preparación del mismo y uso del mismo
Inventor: LIANG XIAO
IPC: A61P35/00
Filed: 2022-11-14
Abstract: Se relaciona un conjugado de anticuerpo-fármaco anti-CLDN 18.2, método de preparación y uso del mismo. El conjugado de anticuerpo-fármaco y la composición del mismo es capaz de unirse eficazmente a CLDN 18.2 e inhibir el crecimiento de tumores positivos para Claudin 18.2. También se relaciona una composición farmacéutica que comprende el conjugado de anticuerpo-fármaco o la composición, y el uso de la composición farmacéutica en la preparación de un medicamento para prevenir y/o tratar tumores.
Patent EC-SP11011552-A (EC)
Title: Administracion continua de cilengitida en tratamientos contra el cancer
Inventor: PICARD MARTIN ANDREAS
IPC: A61K33/243
Filed: 2011-12-23
Abstract: La invención se relaciona con una terapia de combinación para el tratamiento de tumores y metástasis tumorales que comprende la administración continua de ligandos de integrina, preferiblemente antagonistas de integrina junto con un agente coterapéutico o formas de terapia que tengan eficacia sinergística cuando se administren de manera consecutiva con los ligandos, tales como agentes quimioterapéuticos y/o radioterapia.
Patent EC-SP13012731-A (EC)
Title: Método, sistema y aparato para la separación en el procesamiento de materias primas
Inventor: PAVEL STEPHEN K
IPC: C10G47/30
Filed: 2013-07-03
Abstract: Se divulga un método, sistema y aparato para la separación en el procesamiento de materias primas. De acuerdo con una realización, un aparato comprende un recipiente tubular que tiene una entrada de tubo cuadrado y una salida de vapor, donde la salida de vapor está ubicada en la parte superior del recipiente tubular, y donde la entrada de tubo cuadrado es tangencial a un diámetro interior del recipiente tubular; un barril ubicado debajo del recipiente tubular; y una válvula de cuchilla de doble aislamiento ubicada entre el recipiente tubular y el barril, donde una corriente de gas y sólidos entra al recipiente tubular a través de la entrada de tubo cuadrado, y donde el gas y los sólidos se separaran usando fuerza centrífuga, y donde el gas sale por la salida de vapor y los sólidos se recogen en el barril.
Patent EE-200200675-A (EE)
Inventor: SCHROER FREDERIKUS JOHANNES
IPC: A61H39/04
Filed: 2001-06-07
Abstract: Vasoregulation device for use during the phase prior to headache, in particular migraine, for applying pressure at least locally to one or more veins on the outside of the head, in order to restrict the flow of blood through the said veins, at least comprising pressure-exerting means where is said pressure-exerting means are designed to apply a pressure of 0,01 - 0,03 N/mm<2>. The device is thus intended for preventative use at the onset of migraine. <IMAGE>
Patent GB-189702126-A (GB)
Title: Improvements in, and Apparatus for, Applying Heat to the Surfaces of Armour Plates and other Articles.
Inventor: TRESSIDER TOLMIE JOHN
Filed: 1897-01-26
Granted: 1897-12-11
Abstract: 2126. Tresidder, T. J. Jan. 26. Heating-furnaces for iron and steel.-A furnace for applying heat to the surface of armour plates and the like is shown in elevation in Fig. 3. It consists of a number of separate heaters C pivoted in adjustable trunnion bearings and supported by screwed rods l, so that flat or curved plates can be heated uniformly. The heaters depend from a main g supplying mixed gas and air under pressure from a fan or the like, and there are suitable valves for regulating or cutting-off the supply to individual heaters. Fig. 1 shows an enlarged sectional elevation of a heater consisting of a mixing-chamber b and tubes or blowpipes d fitting into a firebrick facing e below and surrounded by a water jacket C. An annular furnace for heating projectiles is shown in Fig. 6. The mixed gas and air are supplied by pipes a to a mixing-chamber b, and cooling-water enters the chamber c by a pipe c<2> and escapes by a pipe c<3>. The projectile is supported upon a simple form of crane, so that it can be easily handled ; and after heating it may be transferred to a cooling-mantlef, Fig. 8, having a perforated inner shell t and supplied with water from an inlet g.
Patent GB-189704140-A (GB)
Title: Improvements in the Manufacture of Figured Pile Fabrics.
Inventor: MORTON JAMES
Filed: 1897-02-16
Granted: 1898-01-29
Abstract: 4140. Morton, J. Feb. 16. Embossed fabrics.-Imitation figured-pile fabrics are made in an ordinary jacquard loom from a cotton warp A and weft B to form the groundwork, and a woollen weft C and light binding warps D to form the raised imitation pile portion on one or both sides. The fabric is then fulled and combed to form the nap or imitation pile.
Patent GB-189713078-A (GB)
Title: Improvements in Devices for Disengaging Animals of Draft from Vehicles.
Inventor: WUELFING RUDOLF
Filed: 1897-05-27
Granted: 1897-07-10
Abstract: 13,078. W³lfing, R. May 27. Runaway or fa l l e n horses, releasing.-A fixed jaw b is mounted at each end of the whipple-tree A and has a jaw a pivoted to it at c. A spring lever f pivoted at g has a recess g<1> and the jaw a has a projection d. By pulling the chain i, the projection d is engaged, the jaw a turns on its pivot, and the trace is released.
Patent GB-189713821-A (GB)
Title: Improvements in Apparatus for Drying and Hardening Wood.
Inventor: LEBIODA GEORGE FREDERIC
Filed: 1897-06-04
Granted: 1897-11-13
Abstract: 13,821. Lebioda, G. F. Nov. 14, A.D. 1896, [date claimed under Sec. 103 of Patents &c. Act, A.D. 1883]. Wood, treating. -The piece of wood i to be dried and hardened is placed on the plate f, which i s perforated with a number o f holes for the passage of air and heat, and is furnished with two transverse grooves in which fit the projections m on the side plates k which are also perforated. The side plates k and the weight r are made to press against the block of wood by any suitable means, the pressure being gradually increased during the process of drying. The whole apparatus is enclosed in a drying-chamber which is closed during the drying process, and is heated by steam pipes or in any other suitable manner.
Patent GB-189714166-A (GB)
Title: New or Improved Band Clip for Fixing or Holding Articles together.
Inventor: KEMPSTER JOHN JOSEPH
Filed: 1897-06-10
Granted: 1898-05-28
Abstract: 14,166. Kempster, J. J. June 10. Luggage and umbrella holders. - Relates to a band clip for holding articles in position such as umbrellas, capes, &c. on the frame of a perambulator or other carriage. In Fig. 1, an india-rubber band a, with an eyelet b and thickened end c, is passed round the umbrella, cape, &c. and hooked over a hook d, which may also serve to secure the end c to the framework &c., or the end may be independently secured. The thickened end and hook may be replaced by a buckle. In Fig. 6, the band has an intermediate thickened portion j to receive the inflator &c. h, and is first passed round the tube i, engaging a stud b<1> on the end of the band, and then round both, and again secured on the stud.
Patent GB-189716500-A (GB)
Title: Improvements in or relating to Supports or Rests for Cycles.
Inventor: BOULT ALFRED JULIUS
Filed: 1897-07-12
Granted: 1897-08-14
Abstract: 16,500. Boult, A. J., [Lamour, J.]. July 12. Stands.-Relates to a support or rest for cycles, which may be folded up in a convenient manner. A clamp A consisting of two parts bolted together is attached to the tube B, pieces of leather, rubber, &c. being interposed between the clamp and tube to prevent injury to the latter. The clamp carries at one end two lugs E, E' against which rests the support, which consists of jointed rods F, H and two rods L, K jointed at M to the rod H to engage with the ground. Stops l, h are provided to keep the rods in position.
Patent GB-189720583-A (GB)
Title: An Improvement in Electric Arc Lamps.
Inventor: BROCKIE JAMES
Filed: 1897-09-07
Granted: 1898-07-09
Abstract: 20,583. Brockie, J. Sept. 7. Arc lamps.-The upper carbon is carried by a rod B, notched at intervals such as an inch, and controlled by a piston B<2>. A series solenoid A acts on a core A', which is controlled by another piston A<2> and carries a pawl D to engage the notches in the rod B. An arm of the pawl meets a stop E when the core descends considerably, the rod B being the released so that it falls with the upper carbon and the pawl engages the next notch. The core A<1> may be tubular and contain the rod B, as shown in the Figure, or the rod B may work in separate guides, and the pawl be carried by a lever connected to the core. The arc may be enclosed.
Patent GB-189722887-A (GB)
Title: Improvements in Hand Fire-extinguishers.
Inventor: STEVENS SAMUEL MASTIN
Filed: 1897-10-05
Granted: 1898-02-12
Abstract: 22,887. Stevens, S. M. Oct. 5. Spray - producers. - A nozzle b of conical or other form is provided with an orifice c having a serrated edge d with the points turned in towards the centre of the orifice so as to break up and distribute the jet. The nozzle may be formed from a single sheet stamped out in suitable shape.
Patent GB-189724574-A (GB)
Title: An Improved System of Day and Night Advertising, applied to Vehicles, and Apparatus for Operating the same.
Inventor: SAUNDERS RICHARD EDWARD
Filed: 1897-10-23
Granted: 1898-01-15
Abstract: 24,574. Saunders, R. E. Oct. 23. Advertising.-Multi-coloured bands or discs, such as those described in Specification No. 18,365, A.D. 1897, are applied to vehicles, being moved behind transparent lettering forming advertisements on the vehicles by gearing connected with the wheels or with the actuating-motor, or by electricity, which also serves as an illuminating agent, generated by the movement of the wheels &c. In Fig. 3, a band K is shown with notches K<2> at the edges to engage with the teeth of pinions J, J on the actuating-rollers g, g<1>.
Patent GB-189729155-A (GB)
Title: Improvements in Electric Lamp Holders.
Inventor: JOSEPH EDWARD LIONEL
Filed: 1897-12-09
Granted: 1898-01-15
Abstract: 29,155. Joseph, E. L. Dec. 9. Incandescent lamps, holders for. A flanged cylindrical insulator a is made in two halves, as shown in section in Fig. 5, and with recesses g to receive two plunger holders h, which have been previously secured to the supply conductors by screws i. These parts, having been put together, are placed in a metal socket b, Fig. 2, and secured by a top-piece e and screw coupling-sleeve f. A projection on the socket b enters a recess l in the insulator to prevent turning. One half of the insulator may have a projection fitting into a recess in the other, between the plunger holders.
Patent GB-189801658-A (GB)
Title: An Improved Attachment or Device for Steadying the Steering Wheel of Cycles.
Inventor: HILL EDMUND ERNEST
Filed: 1898-01-21
Granted: 1898-11-26
Abstract: 1658. Hill, E. E. Jan. 21. Steering-mechanism.- Relates to an arrangement for steadying the steering-wheel of bicycles &c. Lugs A on the fork crown are connected by elastic cords C with projections B on a clamp fixed to the lower tube of the frame. The cords are provided with swivel hooks which engage with eyes on the parts A and B.
Patent GB-189803841-A (GB)
Title: Improvements in the Method of and Means Employed for Connecting Electric Glow Lamps to Main Conductors.
Inventor: PALM FRIEDRICH
Filed: 1898-02-16
Granted: 1898-03-26
Abstract: 3841. Palm, F. Feb. 16. Incandescent lamps; supporting lamps.-Lamps are placed directly on bare main conductors, which are stretched and held in insulating-clamps. In one arrangement, Fig. 1, the lamp is set in cement in a cap 1, two plate springs 2 being also set in the cement, to grip the conductors 4. The surface of the cement is waxed. The springs may be formed to grip conductors parallel to the filament. In another arrangement, Fig. 5, the lamp is provided with a cap 1 carrying two terminal pins 8. These enter sockets and engage springs in a holder 3. Each socket carries a curved spring bearing at its ends on one of the conductors 4, which rest on an insulator 5.
Patent GB-189805477-A (GB)
Title: A Process for Obtaining Strong Tuberculosis Toxins from Tubercle Bacilli.
Inventor: IMRAY OLIVER
Filed: 1898-03-05
Granted: 1899-03-04
Abstract: 5477. Imray, O., [Farbwerke vorm. Meister, Lucius, & Br³ning]. March 5. Toxines.-Strong tuberculosis toxines are made from the residues obtained in the processes previously employed for the manufacture of tuberculin and tuberculoplasmin. These residues, deprived of fat, are heated with water, aqueous glycerine, or solutions of salt to a temperature of about 150‹ C. in vacuo. The fluid is separated in a centrifugal apparatus, and from it the toxinemay be obtained in a solid form by precipitation with alcohol.
Patent GB-189807189-A (GB)
Title: Improvements relating to Bottle and like Stoppers.
Inventor: HINDE WILLIAM LORD BALLIN
Filed: 1898-03-24
Granted: 1899-01-28
Abstract: 7189. Hinde, W. L. B. March 24. Drawings to Specification. Sponges.-A piece of sponge or other absorbent material is removably fitted to the sprinkling- stopper of a bottle &c. containing hair wash &c., for use in applying the liquid.
Patent GB-189811050-A (GB)
Title: Improvements in or relating to Bellows.
Inventor: BINGHAM WILLIAM JAMES
Filed: 1898-05-14
Granted: 1899-02-25
Abstract: 11,050. Bingham, W. J. May 14. Smiths' forges, bellows for. Single and double acting bellows are so constructed that they may be taken to pieces and packed in a small compass. The standards B are jointed at C, and the handle at H. To allow the chambers to collapse, the back pipe is detachable ; it is composed of two bends D, D<1> with flanges to fix them to the bellows, and sockets F which receive the ends of the pipes E and are packed with leather. india-rubber, &c. The balance weights G are composed of two hollow hemispheres held together by a bolt passing through the middle.
Patent GB-189812188-A (GB)
Title: Improvements in Apparatus for the Manufacture of Drawn Tubes.
Filed: 1898-05-28
Granted: 1899-03-25
Abstract: 12,188. Ehrhardt. H., and Universal Weldless Steel Tubes Co., (Ehrhardt's Process). May 28. D r a w i n g. - In a machine for drawing pipes and tubes bv passing them on a mandrel through dies, the mandrel and dies are both moved to approach one another during drawing. The draw-bench C has sliding headstocks A, B, operated by bevel gearing through racks and pinions D, E from a shaft F. This shaft is driven from a belt pulley h through a reversing crown train H, g<2>, g<3> and clutches i, i<1>. These clutches may be operated as desired by a handlever K, and are connected by links j<3>, j<4>, j<2> to a lever J, operated at each end of the stroke by stops (one a, of which is shown) on the headstock to reverse the motion. The tube l on the mandrel L is forced through a guide N<2> and two or more successive dies N, N', and then between rolls N<3>, which slightly distort it so that it may be easily stripped from the mandrel. The blocks n, which carry the guide, dies, and rolls, are connected by links m<4>, Fig. 4, to arms m<3> on a counterweighted rockshaft m<1>, mounted in a slotted rest M. The blocks can thus be raised to rest in the slots m, to allow more space for setting the work on the mandrel.
Patent GB-189816996-A (GB)
Title: Improvements in Rendering Fire Proof Wood, Textile Fabrics, Paper Pulp, Straw, and the like.
Inventor: LITYNSKI LEOPOLD
Filed: 1898-08-06
Granted: 1899-06-24
Abstract: 16,996. Litynski, L., Rodakiewiez, A., and Kurowski, F. Aug. 6. Fireproof paper.-Relates to means for fireproofing wood, paper pulp, straw, &c. The wood &c., is impregnated with a liquid prepared by mixing a solution of potassium carbonate and boracic acid with an ammoniacal solution of magnesium carbonate and boracic acid. The liquid also acts as a preservative for the wood &c.
Patent GB-189901216-A (GB)
Title: Improvement in Locking Devices for Miners' and like Safety Lamps.
Inventor: DEBUS WILHELM
Filed: 1899-01-18
Granted: 1899-07-08
Abstract: 1216. Debus, W. Jan. 18. Miners' and like safety lamps.-Relates to a locking- device which can only be unfastened by means o f a powerful electro - magnet. The parts are so arranged that, when the reservoir d is screwed home, a thimble h thereon coincides with a recess a in the ring r to allow of the insertion of a hollow bolt b with elastic tongues k. These tongues then open, as shown in Fig. 1, and prevent the withdrawal of the bolt until the introduction of a powerful electromagnet m causes the tongues k to close around the bolt b, as shown in Fig. 3.
Patent GB-189902885-A (GB)
Title: An Improved Instrument for use in Making Internal Medicinal Applications to Internal Organs of the Body.
Inventor: SMITH ELMORE OSCAR
Filed: 1899-02-09
Granted: 1899-11-18
Abstract: 2885. Smith, E. O., and McClearey, A. S. Feb. 9. Medicines, administering; uterine appliances.- Relates to an instrument for making local medicinal applications to internal organs of the body, such as the womb. The instrument consists of a tube 1, suitably curved at its front end 2, and provided at its rear end with a cup 8 for receiving the medicament, this cup having an opening into the tube. To enable the front end of the tube to be inserted into the womb, the mouth of the latter is dilated by means of a rod 13 provided at its front end with a wedge-shaped enlargement 14, and at its rear end with a handle 15. After insertion of the tube, the rod 13 is withdrawn, and a dressing, in the form of a cord, fed through the tube by means of a second rod 16, having a notched end 17, which is moved backwards and forwards in the tube. The cord may be prevented from backward movement by a spring inserted through the opening in the tube normally closed by a sleeve 4.
Patent GB-189903251-A (GB)
Title: Improvements in Graters for Nutmegs, Cocoanuts, and the like.
Inventor: HEY SAMUEL
Filed: 1899-02-14
Granted: 1899-04-01
Abstract: 3251. Hey, S., [Edgar Manufacturing Co.]. Feb. 14. Graters for nutmegs, coco-nuts, chocolate, &c. The grating-plate a, which may be cylindrical or semi-cylindrical, is carried by rings b so that it may be rotated by the handle b<1>. The receptacle d, having a screw cap d<6> fitted with a spring d<3>, is fitted with ears d<1> embracing guide-rods c. It may then be moved longitudinally over the grater. In a modified form of receptacle, an opening is provided in the side for the insertion of the nutmeg or the like, and the pressure plate may be fitted with a handle in addition to the spring to give increased pressure while grating. The aperture may be closed by a sliding sleeve. In a semicylindrical grater, the handle is attached to the bottom and the grating-plate is rocked.
Patent GB-189911371-A (GB)
Title: Improvements in or connected with the Raising of Water.
Inventor: YOUNG GEORGE ROMEO
Filed: 1899-05-31
Granted: 1900-04-14
Abstract: 11,371. Young, G. R., and Shaw, C. Nov. 23, A.D. 1898, [date applied for under Sec. 103 of Patents &c. Act, A.D. 1883]. Raising liquids by aÙrating ascending column.- The water from a number of supply wells A is forced into a collecting-well D of about twice their depth, and is thence forced into a separating-tank G. The air pressure in this tank, still above that of the atmosphere, is utilized to force the water still higher by the pipe H ; and the air itself raises the water from the wells A. The body of water in the tank G has a regulating effect on the system.
Patent GB-189919104-A (GB)
Title: Improvements in Pillar and Wall Letter Boxes.
Inventor: KNIGHT CHARLES EDWARD
Filed: 1899-09-22
Granted: 1900-07-28
Abstract: 19,104. Knight, C. E. Sept. 22. Letter-boxes. - The upper part b of the box, provided with the letter slit c, is divided from the lower part a by a partition f, which is balanced on a knife-edge g so as to be readily tilted by the weight of a letter &c. The partition has a toothed sector h, which gears with a slide e which is thus caused to cover the slit when the partition is tilted by means of a letter &c. guided from the slit by an incline d.
Patent GB-189920693-A (GB)
Title: Improvements in Sporting and Tourist's Umbrellas.
Inventor: LOEPER ANNA VON
Filed: 1899-10-16
Granted: 1900-06-30
Abstract: 20,693. Loeper, A. von. Oct. 16. Drawings to Specification. Attaching articles to wearing-apparel.-In order to attach sporting and tourists' umbrellas to the body and thereby leave the hands free for steering a bicycle, handling an alpenstock, &c., a belt is constructed with metal plates and with a flap in such a way as to secure the handle of the umbrella in the belt.
Patent GB-189922016-A (GB)
Title: Improvements in Electrical Switches for Telephonic Systems and other purposes.
Inventor: BYNG MAX
Filed: 1899-11-03
Granted: 1900-01-27
Abstract: 22,016. Byng, M., and Bell, F. G. Nov. 3. Switches. - Relates to means for securing in telephone systems &c. that a switch arm is properly upon its contact-stud. In the form shown in Figs. 1 and 2, the contact-arm A is pivoted to a plate E, suitably supported on a switchboard D, and rubs over contacts b. The plate E has sunken hemispherical recesses corresponding to the contacts b, and a ball g works in a hole in the contact-arm A. This ball is pressed by a spring h, and falls into a recess with an audible click. Figs. 5 and 7 show a sliding switch, the pointer H serving as an indicator.
Patent GB-189924162-A (GB)
Title: Improvements in Time Indicators for Chess or other Games.
Inventor: WALKER SAMUEL
Filed: 1899-12-05
Granted: 1900-11-03
Abstract: 24,162. Walker, S. Dec 5. Time-checks for games; scoring and marking.- Relates to a time-check for chess &c. arranged so that the indicating-hand is driven forward while one player is considering his moves and backwards when the other player is doing so. The apparatus may be combined with a clock and with an indicator to register the number of moves. The hand i moving over a dial is carried by a sleeve g on a pinion f which is frictionally driven from the minute spindle of a clock train a. The spindle carries a pinion c gearing with a loose pinion d which actuates a pinionj. The pinion j is forced upwards by a spring so as to engage the pinion f and reverse the hand, but can be disengaged therefrom by pressing a stud p on a lever m a projection o on which bears on the pinion as shown. When the stud q is pressed, the lever is tilted, allowing the pinion to rise. The pinions f and j are preferably bevelled to ensure engagement. An ordinary clock may be driven from the going-train of the apparatus. A counter of the usual kind is combined with the apparatus.
Patent GB-190005387-A (GB)
Title: Improvements in Apparatus for Wireless Telegraphy.
Inventor: MARCONI GUGLIELMO
Filed: 1900-03-21
Granted: 1901-06-21
Abstract: 5387. Marconi, G. March 21. Wireless telegraphy.-Relates to improvements in systems of wireless telegraphy such as described in Specifications No. 12,039, A.D. 1896, No. 29,306, A.D. 1897, Nos. 12,325 and 12,326, A.D. 1898, and Nos. 6982 and 25,186, A.D. 1899. The aÙrial conductors are constructed as two concentric surfaces a, b, or as two parallel wires, one of which is connected to earth, and both are attached to the oscillator g at the transmitting-station or to an induction coil c at the receiving-station. Impedances i, i<1> are included in the circuits as shown for syntonizing, the transmitting-impedance being capable of great variation for syntonizing with any particular receiver of the system.