baber/WOPTO huggingface dataset:
Patent EP-1282448-A1 (EP)
Inventor: GLUESENKAMP KARL-HEINZ
IPC: C07D487/08
Filed: 2001-05-17
Abstract: The present invention related to heterobifunctional cross-linkers substituted by a cell surface binding group or a cell recognising group, and also by a bio-active group, the bio-active group attached to a carbonyl of the cross-linker by an acid labile bond. Examples of suitable bio-active groups include an immunomodulator and an anti-neoplastic group. The conjugate enables, for example, the coupling of immunomodulators ex vivo to a target cell, for example a tumor antigen presenting cell. The conjugate can act as a non-toxic prodrug carrying a cytotoxin, for example, to a target tissue site, where the pH-dependency of the labile amide bond provides for cell selectivity of the masked cytotoxin. The invention further relates to a method for producing the cross-linkers, their use in treating disease, and ex-vivo cell labeling.
Patent EP-1289572-A1 (EP)
Inventor: WALKER BRIAN KEITH
IPC: F24D17/00
Filed: 2001-06-13
Abstract: L'invention porte sur un dispositif (100) de traitement de l'eau par la chaleur comprenant une zone de chauffage confinée, un passage (15) servant à l'alimentation en eau de ladite zone (23) de chauffage, un contrôleur (27) empêchant l'eau chauffée de quitter le dispositif avant que tous les pathogènes ne soient détruits, et un substrat antimicrobien (20) empêchant les pathogènes présents dans l'eau non chauffée de quitter le dispositif.
Patent EP-1294328-A1 (EP)
Inventor: AUSTRING ROBERT
IPC: A61F9/013
Filed: 2001-06-20
Abstract: L'invention concerne une lame et un ensemble lame. Ladite lame comprend un bord avant aiguisé et biseauté (13), deux bords latéraux (14, 16) se rencontrant en un point (18) espacé du bord avant et au moins une structure de fixation (20, 22) faisant saillie à partir de chaque bord latéral. Un porte-lame qui dépasse des bords latéraux et des structures de fixation de la lame et qui repose sur une surface supérieure de la lame, est fixé sur la lame par une partie qui reçoit les structures de fixation. Le porte-lame comprend une ouverture pratiquée dans une surface découverte afin de recevoir un prolongement d'un mécanisme d'entraînement, de sorte que, lorsque le mécanisme d'entraînement est activé, la lame vibre latéralement lorsqu'elle est entraînée par une tige tournant le long d'un trajet circulaire.
Patent EP-1301525-A1 (EP)
Title: Transformation d'une composition de cellules souches traitees a l'aide d'un agent de blocage du facteur de croissance beta (tgf-beta), et procede correspondant
Inventor: BARTELMEZ STEPHEN H
IPC: A61K35/12
Filed: 2001-07-06
Abstract: L'invention concerne des compositions de cellules souches pluripotentielles traitées à l'aide d'un agent de blocage du TGF-ß et les procédés utilisant lesdites compositions. Les cellules souches traitées à l'aide d'un agent de blocage du TGF-ß, qui sont viables sur une longue période de temps en culture, sans réplication ni différenciation, sont capables, dès leur transfert dans des conditions appropriées, de reconstitution hématopoïétique à long terme.
Patent EP-1313726-A1 (EP)
Inventor: HENNEQUIN LAURENT FRANCOIS AND
IPC: A61P35/00
Filed: 2001-08-08
Abstract: L'invention concerne des composants de formule (I) dans laquelle : soit l'un des composants suivants G1, G2, G3, G4 et G5 est du nitrogène et les quatre autres sont des éléments -CH-, ou G1, G2, G3, G4 et G5 sont tous -CH-; Z représente -O-, -NH-, -S-, -CH2- ou une liaison directe; Z est lié à l'un des G1, G2, G3 et G4; n est un nombre entier compris entre 0 et 5; m représente un nombre entier compris entre 0 et 3; Ra représente l'hydrogène ou le fluor; R?b, R1 et R2¿ sont définis ici et le sel de ceux-ci, le procédé de fabrication de ces composants, de compositions pharmaceutiques contenant un composant de formule I ou un sel pharmaceutiquement acceptable de ceux-ci comme ingrédient actif et l'utilisation d'un composant de formule I dans la préparation d'un médicament pour la production d'un effet de réduction de la perméabilité vasculaire et/ou antiangiogénique chez des animaux à sang chaud. Les composants de formule I et les sels pharmaceutiquement acceptables de ceux-ci inhibent les effets du VEGF, une propriété précieuse dans le traitement de nombreuses affections comprenant le cancer et l'arthrite rhumatoïde.
Patent EP-1332636-A1 (EP)
Inventor: KELLER RALF
IPC: H04W16/02
Filed: 2001-06-26
Abstract: Method of arranging a cellular radio network in a geographical area which is already covered by an existing cellular radio network, wherein cell clusters of the cellular radio network to be introduced and using a specific transmission frequency are located in areas determined by connecting at least two cells of the existing cellular radio network using the specific transmission frequency, and wherein the cell clusters are arranged such that they do not overlap with the cells of the existing cellular radio network. The cell clusters of the introduced cellular radio network may be adjusted by reducing the cell size of cell clusters of the introduced cellular radio network, and by introducing new cells into cell clusters of the introduced cellular radio network. The invention allows to reuse frequencies of an existing cellular radio network by an introduced cellular radio network in the same geographical area.
Patent EP-1328274-A1 (EP)
Inventor: BAGGOTT JOSEPH
IPC: A61K9/52
Filed: 2001-08-09
Abstract: Les symptômes délétères d'une maladie auto-immune chez un patient souffrant de symptômes d'une maladie auto-immune, peuvent être soulagés par administration simultanée d'une quantité efficace inhibitrice immunitaire induite par une cellule d'au moins un inhibiteur de la dihydrofolate reductase et d'un folate composé de manière à présenter une action différée dans un support.
Patent EP-1307709-A1 (EP)
Title: Aktiver magnetfeldsensor, dessen verwendung, verfahren und vorrichtung
Inventor: LOHBERG PETER
IPC: G01D5/16
Filed: 2001-08-01
Abstract: Beschrieben ist ein aktiver Magnetfeldsensor, insbesondere Radlagersensoreinheit, umfassend mindestens ein Magnetsensorelement (10, 21, 36) zur Umwandlung eines zeitlich periodischen magnetischen Feldes in ein zeitlich periodisches elektrisches Sensorsignal an Signalausgängen (37, 31) und eine elektronische Signalauswerteschaltung, wobei der Magnetfeldsensor über eine Sensorschnittstelle elektrisch versorgt wird, worin in zwei oder mehreren getrennten, jeweils den Sensorsignalen zugeordneten, Signalkanälen der Auswerteschaltung eine aktive elektrische Verarbeitung von periodischen Signalen (38, 39) des Magnetsensorelementes erfolgt.
Patent EP-1322611-A1 (EP)
Inventor: SANGANEE HITESH
IPC: A61K31/4545
Filed: 2001-08-30
Abstract: L'invention concerne des composés de la formule (I): utilisés comme modulateurs de la chimiokine et de l'activité du récepteur H1. Ces composés sont particulièrement utiles dans le traitement de l'asthme et de la rhinite.
Patent EP-1315953-A1 (EP)
Inventor: MARK HOWARD
IPC: G01J3/18
Filed: 2001-08-10
Abstract: Cette invention se rapporte à un procédé automatisé servant à modéliser des données spectrales et consistant à cet effet à accéder à un groupe de données spectrales correspondant à chaque échantillon parmi plusieurs échantillons, à chacun de ces groupes étant associée au moins une valeur constitutive mesurée indépendamment (201). Des transformées de données sont appliquées au groupe des données spectrales pour produire, pour chaque échantillon, un groupe de données spectrales transformé et non transformée qui, avec leurs valeurs constitutives associées, sont divisées en un sous-groupe d'étalonnage (231) et un sous-groupes de validation (232). L'une ou plusieurs des analyses suivantes, analyse par la technique des moindres carrés partiels, analyse par régression en composantes principales, analyse par réseaux neuronaux ou analyse par régression linéaire multiple, sont appliquées aux sous-ensembles de données d'étalonnage, pour obtenir des équations de modélisation correspondantes, destinées à permettre la prédiction de la quantité de substances cibles contenue dans un échantillon. L'équation de modélisation avec la meilleure corrélation entre les données spectrales dans le sous-groupe de validation et les valeurs constitutives correspondantes dans le sous-groupe de validation est identifiée, de préférence en fonction de l'erreur type d'estimation SEE et SEP.
Patent EP-1317569-A1 (EP)
Inventor: STERN SETH R
IPC: B01L3/00
Filed: 2001-09-13
Abstract: In a method for performing a hot start polymerase chain reaction, a reaction mixture including a primer, a template molecule, and a buffer-but no polymerase enzyme-is loaded in a reaction channel of a microfluidic device. An electrical current is applied to heat the reaction channel. A polymerase enzyme is delivered into the reaction channel, and the reaction channel is subjected to conditions such that the hot start polymerase chain reaction is performed. In a method for performing a temperature mediated reaction, a first component of the temperature mediated reaction is loaded in a reaction channel of a microfluidic device. An electrical current is applied to heat the reaction channel. A second component of the temperature mediated reaction is delivered into the reaction channel, and the reaction channel is subjected to conditions such that the temperature mediated reaction is performed.
Patent EP-1386089-A1 (EP)
Inventor: STONE ROGER
IPC: F16B5/02
Filed: 2001-09-12
Abstract: The invention comprises a tolerance compensating mounting device comprising a bushing having an internal and external thread. The bushing is threaded into a part to be mounted to a surface. A bolt is then threaded into a bushing bore using the internal threads. The internal threads cause an interference fit between the bolt shank and the threads, temporarily preventing further insertion of the bolt. The bolt is then turned further, thereby turning the bushing and causing the bushing to unscrew from the part toward the mounting surface until the bushing seats on the mounting surface, thereby completely compensating for a tolerance gap. As the bolt is turned further, at a relatively low torque the sacrificial internal threads are stripped allowing the bolt to be fully torqued into the mounting surface hole, thereby simultaneously connecting the components with a properly torqued connection while compensating for a tolerance gap.
Patent EP-1331977-A1 (EP)
Title: Coupelle de centrifugeuse de sang a compartiment rempla able pour support de filtre
Inventor: ROMANAUSKAS WILLIAM ANDREW
IPC: B01D17/038
Filed: 2001-09-19
Abstract: L'invention concerne une coupelle de centrifugeuse (10), qui contient un premier article (60), comportant un compartiment (30) qui renferme un second article (70), et présentant un arrangement (11) qui permet de fixer le compartiment (30) à une surface extérieure de la coupelle de la centrifugeuse (10).
Patent EP-1335880-A1 (EP)
Title: Method for co-precipitating actinides and method for preparing mixed actinide oxides
Inventor: MESMIN CLAIRE
IPC: C07C51/43
Filed: 2001-10-04
Abstract: The invention concerns a method for co-precipitating actinides in oxidation state (IV) which consists in: adding an organic complexing agent selective of actinides (IV) and consisting only of oxygen, carbon, nitrogen and hydrogen atoms, to a first aqueous solution of an An<1> actinide in oxidation state (IV) to form an An<1> actinide complex in oxidation state (IV); adding said complexing agent to at least a second aqueous solution of an An<2> actinide in oxidation state (IV) to form an An<2> actinide complex in oxidation state (IV); mixing intimately said first and second complex solutions; simultaneously precipitating said at least two complexes of An<1> (IV) and An<2> (IV) actinides derived from said mixture. The invention also concerns a method for preparing mixed oxides by calcining the resulting precipitate. Said mixed oxides can be used in particular for making MOX-type nuclear fuel.
Patent EP-1332125-A1 (EP)
Inventor: JONES RAYMOND VINCENT HEAVON
IPC: C07C29/86
Filed: 2001-10-18
Abstract: A process for the preparation of 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol comprising hydrogenating 4-methyl-2,3,5,6-tetrafluorobenzonitrile to 4-methyl-2,3,5,6-tetrafluorobenzylamine and converting 4-methyl-2,3,5,6-tetrafluorobenzylamine to 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol. The process optionally also comprises the further step of reacting 4-Methyl-2,3,5,6-tetrafluobenzyl alcohol with cis-Z-3-(2-chloro-1,1,1-trifluoro-2-propenyl)-2,2-dimethylcyclopropanecarbonyl chloride to the form tefluthrin. 4-Methyl-2,3,5,6-tetrafluorobenzylamine and salts thereof are also claimed.
Patent EP-1322351-A1 (EP)
Inventor: DAVILA LUIS A
IPC: A61M31/00
Filed: 2001-09-28
Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.
Patent EP-1331998-A1 (EP)
Title: Systeme de synthese combinatoire
Inventor: VAN DAM R MICHAEL
IPC: B01L3/00
Filed: 2001-10-03
Abstract: L'invention concerne un appareil de réactions chimiques permettant de synthétiser un ensemble de composés, ainsi que ses méthodes d'utilisation. Plus précisément, cet appareil de réactions chimiques comprend une base de support solide (100), un premier élément élastique (20) assujetti à la base de support solide (100), et une première pluralité de canaux d'écoulement (104) situés entre la base de support solide et le premier membre élastique (20). Par ailleurs, la base de support solide (100) comprend, dans au moins une partie de la première pluralité de canaux d'écoulement (104), un groupe fonctionnel auquel se fixe les composés. De plus, l'appareil de réactions chimiques de l'invention peut également comprendre un second élément élastique (200) assujetti au premier élément élastique (20). Une pluralité de canaux de pression (304) situés entre les premiers (20) et les seconds (200) éléments élastiques permettent de réguler le débit des liquides dans la première pluralité de canaux d'écoulements (104) et/ou dans la seconde pluralité de canaux d'écoulements (108).
Patent EP-1332458-A1 (EP)
Inventor: HERZIGER KATHY ANN
IPC: G06Q20/18
Filed: 2001-10-02
Abstract: In some preferred embodiments of the present invention, an ATM management application is used to provide an ATM operator with a comprehensive set of ATM management information. This ATM management information can enable the ATM operator to increase ATM profitability through improved ATM availability and expense reduction. The ATM management application can include any number of the following modules as per Figure 3; a currency management module-(200), a status inquiry module-(300), a courier service module-(400), an auto balance module-(500), a deposit verification module-(600) and a site analysis and profitability management module-(700).
Patent EP-1343854-A1 (EP)
Title: Binding agent agglomerate, method for the production and use thereof
Inventor: SCHOETTMER BERNHARD
IPC: C08J3/12
Filed: 2001-12-05
Abstract: The invention relates to a particle-shaped binding agent agglomerate, containing at least one natural or synthetic polysaccharide and one synthetic polymer, whereby a 5 wt. % aqueous solution or dispersion of particles with a particle diameter having an over average particle variable interval (Tm) and an aqueous dispersion of particles with a particle diameter having an under average particle variable interval (Tm) after a dissolution time of 1 hr or less, respectively exhibit a viscosity which deviates by less than 20 % from the other respective viscosity.  The invention also relates to a method for producing said particle-shaped binding agent agglomerate, in addition to the use thereof.
Patent EP-1239335-A1 (EP)
Inventor: YAMAGUCHI KIMITOSHI
IPC: G03G9/08
Filed: 2002-03-06
Abstract: A method of developing a latent electrostatic image using a
two-component developer system having a ratio (Vr/Vp) within the range of
1.2<(Vr/Vp)<3 where Vp is the linear speed (Vp)[m/sec] of a photosensitive
member and Vr is the linear speed (Vr) [m/sec] of a developing sleeve, and
applying a biased direct-current V B  [by volt] wherein the developing gap
Gp [cm] as a distance at the nearest point between the photosensitive
member and the developing sleeve is less than or equal to 0.6 mm, the ratio
(ρp/ρa) satisfies the expression (ρp/ρa)<0.7, where ρp is the density[g/cm 3 ] of
the developer at the nearest point between the photosensitive member and
the developing sleeve, which is represented by the equation ρp=J/Gp where J
is the amount of developer scooped up (ρp is also expressed as "density of the
developer" or "density of GP agent" in the specification) and ρa is the bulk
density[g/cm 3 ] of the developer, a carrier for electrophotography is used, the
carrier being made of carrier core particles having a weight average particle
diameter Dv ranging from 25 µm to 45 µm, the particles smaller than 44 µm
representing more than or equal to 70 percent by weight, the particles
smaller than 22 µm representing less than or equal to 7 percent by weight,
the ratio (Dv/Dp) between the weight average particle diameter Dv and the
number average particle diameter Dp satisfying the expression
1≤(Dv/Dp)≤1.30, the core particles being coated with a resin material. The
method eliminates undesired artifacts in the developed image derived from
the developing direction (where the traveling speed of the developing sleeve is
faster than that of the latent electrostatic image).
Patent EP-1262232-A1 (EP)
Inventor: KANAMORI YOSHINORI
IPC: B01J23/755
Filed: 2002-05-15
Abstract: As catalysts for producing aromatic amines by hydrogenating aromatic
nitriles, there are disclosed (1) the catalyst comprising a metal catalyst
component comprising Ni and/or Co and a specific amount of zirconia as a
carrier component, which is prepared by drying, calcining and forming a
precipitate produced by adding an aqueous solution containing soluble salts of
the metal catalyst component and the carrier component to an aqueous alkali
solution; and (2) the catalyst comprising the metal catalyst component and the
carrier component, which is prepared by filtering a precipitate produced by
adding an aqueous solution containing soluble salts of the metal catalyst
component and the carrier component to an aqueous alkali solution; forming
the precipitate without drying to obtain a formed product; and subjecting the
formed product to drying and then calcining. These catalysts are free from
breaking owing to rapid generation of methane and evaporation of liquid
ammonia by hydrogenolysis of high boiling by-products of the hydrogenation
when reactivated after deactivation of the catalyst, which allows the long-term
use of the catalysts.
Patent EP-1356984-A1 (EP)
Inventor: JEONG CHAN HO
IPC: B60N2/015
Filed: 2002-07-02
Abstract: The detachable seat for a vehicle includes a seat bracket (100) at the bottom thereof, which is
detachably coupled with guide grooves (410) and front (421) and rear (422) strikers formed in a floor panel
of the vehicle. The bracket (100) comprises a body unit (110) including a bracket body, front
engaging grooves (120) formed on both sides of a front lower portion of the bracket body to be
open forward so that the front striker (421) can be inserted thereinto, and rear engaging grooves (130)
formed on both sides of a bottom rear portion of the bracket body to be open downward so
that the rear striker (422) can be inserted thereinto; locking units (200) fastened to both sides of a rear
portion of the body unit for releasing the rear striker from the rear engaging grooves in
response to control of a release lever; and rolling units including first rolling (310) means
rotatably fastened to portions in the rear of the front engaging grooves of the body unit, and
second (320) and third (330) rolling means rotatably fastened to portions in the front and rear of the
rear engaging grooves of the body unit, respectively.
Patent EP-1298504-A1 (EP)
IPC: G05B11/42
Filed: 2002-09-17
Abstract: A method for improving the response behavior of a command controlled system, especially a painting robot in a vehicle production line, where the system is simulated by an equivalent model for which parameters are determined. The model system has overload input signals applied to it and the input signals that produce the desired result are chosen for the real system, so that it responds with the desired response behavior. <??>The invention also relates to a corresponding device.
Patent EP-1312441-A1 (EP)
Inventor: WATANABE AKIRA
IPC: B23Q5/56
Filed: 2002-10-15
Abstract: A machine tool has a spindle head (15) and ball screws (17)
on a saddle (10). The spindle head (15) is provided via
sliding or rolling guide members (16) so as to be linearly
movable. The ball screws (17) move the spindle head (15)
along the guide members (16). Concave sliding or rolling
guide portions (26) parallel to the guide members (16) are
provided on both sides of the guide members (16). 
Counterweights (25) linearly movable on the concave guide
portions (26) in a direction opposite to the spindle head
(15) are provided. Racks (28a, 28b) are provided on opposed
surfaces of the counterweights (25) and the spindle head
(15) along the directions of movement of the spindle head
(15) and the counterweights (25). Pinions (27a, 27b)
meshing with the racks (28a, 28b) are rotatably supported
in the saddle (10). The machine tool can effectively
suppress vibrations of a structure (such as the saddle)
generated during movement of a moving object (such as the
spindle head) relative to the structure by a drive line (such
as the ball screws), and always keep the center of gravity
of an entire relatively moving portion constant.
Patent EP-1331182-A1 (EP)
Inventor: ANDREOLI ANDREA
IPC: B65G51/03
Filed: 2002-10-25
Abstract: A positioning system of guide elements of a conveyor of
articles comprises: at least one guide positioning unit
( 131;133 ) comprising a guide positioning element
( 303,305;403,405 ) adapted to be operatively associated with
a respective guide element ( 135 ) for the positioning
thereof; a system of traction-transmitting cables ( 137 )
operatively associated with the guide positioning unit, for
transmitting traction forces; at least one traction unit
( 131;133 ) associated with the system of traction-transmitting
cables for exerting traction forces on the
system of traction-transmitting cables. The guide
positioning unit is either a driven guide positioning unit
( 133 ), wherein the guide positioning element ( 303,305 ) is
caused to be moved by the traction forces transmitted by the
system of traction-transmitting cables, or a driving guide
positioning unit ( 131 ), comprising a motor group ( 301 )
associated with the guide positioning element. The system of
traction-transmitting cables comprises, in the case of a
driving unit, at least one traction-transmitting cable
( 167,167b,167c,167d ) for transmitting traction forces
between the traction unit and the driving unit; in the case
of a driven unit, the system of traction-transmitting cables 
comprises at least one first traction-transmitting cable
( 167a,167b;167d,167e ) and at least one second traction-transmitting
cable ( 167c,167d;167b;167f ) for transmitting
respective first and second traction forces, respectively
causing the guide positioning element to be moved in a first
direction and in a second direction.