baber/WOPTO huggingface dataset:
Patent NZ-572252-A (NZ)
Title: Stereoselective reduction of a morphinone
Inventor: CHENG LIN
IPC: A61K31/485
Filed: 2007-04-19
Abstract: Disclosed is a synthetic method comprising: § stereoselectively reducing a ketone of a morphinone to form a reduced morphinone of formula (I) using a stereoselective reducing agent selected from sodium triethylborohydride, potassium triethylborohydride, sodium tri-sec-butylborohydride and potassium tri-sec-butylborohydride, wherein R1 is H or a protecting group and § covalently attaching methoxy-PEG to the reduced morphinone, wherein the ratio of alpha epimer to beta epimer in the stereoselectively reduced morphinone is at least 90 to 10.
Patent NZ-577062-A (NZ)
Title: A flexible bag with controlled deformation when stretched and an elastic draw tape
Inventor: FRASER ROBERT W
IPC: B65D33/28
Filed: 2007-12-10
Abstract: Disclosed is a flexible bag comprising at least one sheet of flexible sheet material assembled to form a semi-enclosed container with an opening defined by a periphery. The bag has a drawtape closure for sealing the opening and converting the semi-enclosed container to a closed container. The bag has an upper region adjacent to the drawtape closure and a lower region below the upper region. The sheet material of the drawtape closure exhibits an elastic-like behaviour along at least one axis. The sheet material of the drawtape closure has a first region and a second region. The first region and the second region are comprised of the same material composition and each have an un-tensioned projected path length. The first region undergoes a molecular-level deformation and the second region initially undergoes a geometric deformation when the sheet material is subjected to an applied elongation in a direction parallel to the axis in response to an externally-applied force upon the drawtape closure. The first region and the second region are visually distinct from one another.
Patent NZ-578063-A (NZ)
Title: Cannabinoid CB1 receptor modulators
Inventor: COOPER MARTIN
IPC: A61K31/4155
Filed: 2007-12-17
Abstract: Provided is a compound of formula (I), or a salt, hydrate, solvate, single enantiomer or N-oxide thereof. The compound can be used to treat various diseases or conditions directly or indirectly associated with obesity and overweight selected from metabolic syndrome, type 2 diabetes, cardiovascular disease, metabolic dysfunction, metabolic disease or disorder, or liver disease; or for the treatment of an eating disorder, an addictive disorder, a mental disorder, a neurological disorders, sexual dysfunction, reproductive dysfunction, liver disease or fibrosis-related disease.
Patent NZ-579302-A (NZ)
Title: Multiple-variable dose regimen for treating TNFalpha-related disorders
Inventor: GRANNEMAN GEORGE RICHARD
IPC: A61P37/00
Filed: 2005-04-11
Abstract: Provided is the use of an isolated human anti-TNF alpha antibody, or an antigen-binding portion thereof, in the manufacture of a medicament for treating in a subject in need thereof, an intestinal disorder in which TNF alpha activity is detrimental wherein said subject has lost responsiveness or developed intolerance to infliximab.
Patent NZ-582710-A (NZ)
Title: Ostomy coupling adapter with flexible collar
Inventor: PIONATI NINO
IPC: A61F5/44
Filed: 2008-08-18
Abstract: An adapter (26) is disclosed for an ostomy coupling. The adapter provides a floatable coupling characteristic to an ostomy body fitment that has a non-floatable coupling part. The adapter comprises a first coupling part (34) for attaching to the non-floating coupling part (32) of the body fitment, a second coupling part (36) for releasably attaching to a coupling part (38) of an ostomy appliance (24), and a flexible collar (40) between the first and second coupling parts. The flexible collar permits the second coupling part to be displaced away from the first coupling part, thereby creating a space for an ostomate to manually brace the second coupling part against an attachment force when an appliance is fitted.
Patent NZ-586145-A (NZ)
Title: Method of imaging in crystalline colloidal arrays
Inventor: PURDY SEAN
IPC: C30B5/00
Filed: 2008-12-08
Abstract: A method of producing an image comprises providing an imaging member comprising an array of elements received within a curable matrix composition; curing the matrix composition in a first portion of the imaging member by projecting laser radiation onto the first portion in the configuration of an image, such that the first cured portion exhibits a first optical property; altering another portion of the imaging member; and curing the other portion of the matrix composition, such that the other cured portion exhibits a different optical property from the first portion. The array of elements comprises an ordered array of particles, and the first cured portion diffracts radiation at a first wavelength and the other cured portion diffracts radiation at another wavelength. Also disclosed is a method of producing an image comprising providing an array of elements received within a curable matrix composition; curing a first portion of the matrix composition through a grey-scale positive or negative mask of an image; and curing another portion of the matrix composition. The array of elements comprises an ordered array of particles, and the first cured portion diffracts radiation at a first wavelength and the other cured portion diffracts radiation at another wavelength. Further disclosed is a method of producing a multi-colour image in a crystalline colloidal array comprising providing a plurality of imaging members (24), each imaging member comprising an ordered array of particles received within a curable matrix composition; providing an image mask for each imaging member; exposing each imaging member to actinic radiation (26a) through one of the image masks (20) to produce a plurality of imaged members, each imaged member having a cured image portion (28) and an uncured background portion; curing the uncured portions (30) of the imaged members such that the cured image portion and the cured background portion diffract radiation at differing wavelengths; and stacking the imaged members such that the diffraction of radiation from the cured image portions yields a multi-colour image.
Patent NZ-587102-A (NZ)
Title: A method for extending mold-free shelf life and improving flavor characteristics of baked goods
Inventor: EIJK JOHANNES VAN
IPC: A21D8/04
Filed: 2009-01-28
Abstract: Disclosed is the use of a live yeast strain of the genus Saccharomyces for the inhibition of the growth of mould on a baked food product to extend the shelf life of the food product.
Patent NZ-587455-A (NZ)
Title: Multiple-channel active sensing and switching device
Inventor: PHILLIPS DAVID L
IPC: F04B49/06
Filed: 2009-02-04
Abstract: 587455 Disclosed is a multichannel active sensing and switching device (2). The device (2) includes a multiple sensing and switching module configured to respond to operational conditions of load types such that each load type has a respective load type protection scheme. At least two of the load types have different respective load type protection schemes, and provide load type sensor signals containing information about the operational conditions of the load types. The module is also configured to respond to controller signals and control the operation of each load type in the respective load type protection scheme. Also included is a controller module (6) configured to respond to the load type sensor signals and provide the controller signals in order to control the operation of the each load type in the respective load type protection scheme. This is done in real time so that events are handled as real time tasks immediately and concurrently.
Patent NZ-590425-A (NZ)
Title: Process for removing contaminant from a gaseous stream of carbon dioxide using liquid carbon dioxide as an absorbent
Inventor: FIND RASMUS
IPC: C01B32/50
Filed: 2009-07-03
Abstract: A method for removing at least one contaminant from a gaseous feed stream comprising more than 80 weight % carbon dioxide is disclosed, wherein the method comprises the step of subjecting the gaseous feed stream to an absorption step in an absorption column having a top, bottom and an intermediate section, wherein the absorbent is liquid carbon dioxide and wherein the at least one contaminant is selected from the group consisting of non-polar organic compounds and compounds having a boiling point higher than the boiling point of carbon dioxide under conditions whereby a carbon dioxide enriched gaseous stream and a contaminant rich liquid stream containing at least 95 % (w/w) of the at least one contaminant from the gaseous feed stream, is obtained, wherein the pressure in the absorber is in the range of 6 - 60 bar and the temperature of the gaseous feed stream entering the column is higher than the dew point temperature of carbon dioxide at the prevailing absorption conditions, and wherein the ratio of absorbent to gaseous feed stream is at least 1/9, and wherein the at least one contaminant is selected from the group consisting of oxygenates, esters, aromatic compounds and alcohols..
Patent NZ-592251-A (NZ)
Title: Galactagogue formulation for female mammals
Inventor: FRANCIS RACHEL
IPC: A23C9/20
Filed: 2011-04-14
Abstract: NZ 592251 Disclosed is a galactagogue formulation for female mammals, comprising the following ingredients: liquid milk and/or milk powder in the range 1% to 70% (w/w); at least one gastrointestinal tract native bacterium in the range 0.001% to 20% (w/w); Yeast extract in the range 1% to 20% (w/w); a mixture of medicinal plants in the range of 5% to 20% (w/w); and sugar; wherein the total sugar content of the formulation is in the range of 20% to 40%. Also disclosed is the use of such a formulation as a medicament for the treatment of abnormally reduced milk production in non-human mammals; and in the manufacture of a medicament for the treatment of abnormally reduced milk production.
Patent NZ-595543-A (NZ)
Title: Improved method for manufacturing dipeptidyl peptidase-iv inhibitor and intermediate
Inventor: KWAK WOO YOUNG
IPC: C07C213/00
Filed: 2010-03-30
Abstract: Patent No. 595543 Disclosed is a method for manufacturing dipeptidyl peptidase-IV inhibitor represented by Chemical Formula 1, as shown in the following Reaction Formula 3, the method comprising: (Step 1) preparing a compound represented by Chemical Formula 4 by bonding a compound represented by Chemical Formula 2 and a compound represented by Chemical Formula 3 with peptide bond by reacting them using isochloroformate and a base in the presence of a reaction solvent; and (Step 2) preparing a compound represented by Chemical Formula 1 by removing an amine-protecting group of the compound represented by Chemical Formula 4 produced in the above Step 1.
Patent NZ-598576-A (NZ)
Title: Use of indole derivatives as nurr-1 activators for the application thereof as a medicament for the treatment of parkinson’s disease
Inventor: AMAUDRUT JEROME
IPC: C07D209/10
Filed: 2010-09-10
Abstract: Disclosed herein is a compound derived from indole, especially useful in therapy, characterised in that it is selected from i) the compounds of formula (I), and ii) the pharmaceutically acceptable salts of said compounds of formula (I); Rl, R2, R3, R4, R5, R6, R8, R9 and Cy being as defined in the specification. The invention is applicable in the pharmaceutical field for treating neurodegenerative diseases, especially Parkinson’s disease. In one embodiment the compound is 4-[[1-[[3-(1-methylethyl)phenyl]sulphonyl]-5-(trifluoromethyl)-1H-indol-2-yl]methyl]benzoic acid.
Patent NZ-598807-A (NZ)
Title: Modular system for data center
Inventor: MORALES OSVALDO P
IPC: G06F1/20
Filed: 2010-09-27
Abstract: 598807 A modular computing system 100 for a data centre, comprises one or more data centre modules 102, where at least one of the data centre modules 102 comprises a row of racks comprising two or more rack-mounted computer systems, a cold aisle on one side of the row of racks, a hot aisle on the other side of the row of racks, a module air inlet at one end of the cold aisle, and a module air exit at one end of the hot aisle, and one or more air handling modules 104 coupled to at least one of the data centre modules 102. At least one of the air handling modules 104 comprises at least one fan. The air handling module 104 is configured to provide air to at least one computer system in at least one of the data centre modules 102. At least one of the air handling modules 104 is configured to move air from the module air inlet 130 at the end of the cold aisle, down the cold aisle along at least two racks in the row of racks, through computing systems in the at least two racks in the row of racks, down the hot aisle along the at least two racks in the row of racks, and out the module air exit at the end of the hot aisle.
Patent NZ-600131-A (NZ)
Title: Preoperative planning program and operation support jig for hip replacement arthroplasty
Inventor: ITO TOMOYUKI
IPC: A61B17/56
Filed: 2010-11-24
Abstract: A preoperative planning program for hip replacement arthroplasty and an operation support jig are disclosed. The program causes the computer to execute an image inputting step of inputting a plurality of two-dimensional tomographic images of the lower limbs including the pelvis and the femur; an image reconstructing step of reconstructing a threedimensional image including the pelvis and the femur from the plurality of two-dimensional tomographic images; an artificial joint determining step of determining an artificial joint which is to be set to the acetabular cartridge of the pelvis; a setting position, and a setting direction from the three-dimensional image of the pelvis and the femur; a base jig setting step of setting a three-dimensional image of a base jig having three support columns which are in contact with three landmarks of the pelvis with respect to the three-dimensional image of the pelvis, and a parameter obtaining step of parameterizing and obtaining a direction of a line which passes through the upper end of a support column in immediate proximity to the acetabular cartridge of the pelvis in the three-dimensional image of the base jig and is parallel to the setting direction of the artificial joint.
Patent NZ-600609-A (NZ)
Title: Silicone hydrogel contact lenses that gradually release a hydrophobic comfort agent to the wearer
Inventor: PRUITT JOHN DALLAS
IPC: A61F2/14
Filed: 2009-12-03
Abstract: Disclosed is a process for making a soft silicone hydrogel contact lens capable of gradually delivering a hydrophobic comfort agent during wearing of the contact lens. a) dipping a soft silicone hydrogel contact lens in a solution containing a hydrophobic comfort agent and an organic solvent miscible with water, wherein the soft hydrogel contact lens comprises a polymer matrix including hydrophobic units derived from a silicone-containing monomer or macromer and/or a hydrophobic monomer and hydrophilic units derived from a hydrophilic monomer or macromer, wherein the hydrophobic comfort agent comprises a phospholipid, a monoglyceride, a diglyceride, a triglyceride, a glycolipid, a glyceroglycolipid, a sphingolipid, a sphingo-glycolipid, in or any mixture thereof, b) hydrating the soft silicone hydrogel contact lens having the comfort agent distributed therein in water or a buffered aqueous solution to replace the organic solvent with water or the aqueous solution; and c) placing and sealing the hydrated soft hydrogel contact lens in a lens package containing a lens packaging solution, wherein the soft contact lens is characterized by its capability of gradually releasing the hydrophobic comfort agent from the polymer matrix into the eye of a wearer when being worn.
Patent NZ-604041-A (NZ)
Title: Variable influent flow channel baffle
Inventor: MRKVICKA RODNEY S
IPC: B01D21/24
Filed: 2011-05-24
Abstract: 604041 An input channel and method of making an input channel for the flow of waste water into a grit removal unit (24) is disclosed. The input channel comprises a flat bottom (30) with two side walls extending upwardly from the bottom. One side wall (32) is formed in steps (40) so that the input channel has a larger width higher in the channel to maintain flow velocities within a desired range for varying input flow rates.
Patent NZ-604947-A (NZ)
Title: A barrier
Inventor: HAYES THOMAS COSGROVE
IPC: E03F5/02
Filed: 2012-06-25
Abstract: 604947 A barrier (1) for use with a manhole assembly is disclosed, where the manhole assembly includes a ring component (14) having a lip (20). The barrier includes a body (2), a grating (3) and a bearing surface that is to bear against a top surface of the lip in use. A locking mechanism may also be included consisting of jaws (5) to hold the barrier on one side of the lip and a movable member, either rotated or translated, that blocks removal of the barrier. A padlock (7) could be used to prevent unauthorised removal of the barrier.
Patent NZ-611549-A (NZ)
Title: Slurry phase apparatus
Inventor: STEYNBERG ANDRé PETER
IPC: C10G2/00
Filed: 2011-12-12
Abstract: Disclosed are a slurry phase apparatus (10) and a method of operating a slurry phase apparatus (10). The disclosure notes that regulating pressure in an existing slurry phase apparatus including a fluid impermeable partition has proved difficult as in the event of a gas distributor blockage, the fluid impermeable partition within the apparatus is subject to large differential pressures. The apparatus (10) comprises a slurry vessel (12); a gas distributor (14); a fluid impermeable partition (18) and a pressure transfer passage or conduit (34). The slurry vessel (12) holds a slurry body (37) comprising a liquid and solid particulate material and includes a head space volume (40) above the slurry body (37). The gas distributor (14) in a lower portion of the vessel (12) defines downwards facing gas outlets (32). The fluid impermeable partition (18) spans across the slurry vessel (12) below the gas distributor (14) partitioning the vessel (12) into a slurry volume (19) above the partition (18) and a bottom volume (36) below the partition. The pressure transfer passage or conduit (34) passes through or around the partition (18) and allows transfer of pressure into and from the bottom volume (36). The pressure transfer passage or conduit (34) establishes flow or pressure communication between the bottom volume (36) and the head space volume (40) in the slurry vessel (12) above the slurry volume (19) and thereby maintains a differential pressure. The differential pressure is manipulated by changes in the pressure in the bottom volume (36) to maintain the differential pressure between predefined limits.
Patent NZ-613426-A (NZ)
Title: Dpp iv inhibitor formulations
Inventor: KOHLRAUSCH ANJA
IPC: A61K38/095
Filed: 2007-04-30
Abstract: Disclosed is a process for the preparation of a solid pharmaceutical composition comprising 0.5 mg to 10 mg of a DPP IV inhibitor active ingredient or a salt thereof, a first diluent, a second diluent, a binder, a disintegrant and a lubricant; said process comprising: a) dissolving a binder in a solvent to produce a granulation liquid; b) blending a DPP-IV inhibitor, a first and second diluent, and a disintegrant to produce a pre-mix; c) moistening the pre-mix with the granulation liquid and subsequently granulating the moistened pre-mix; d) optionally sieving the granulated pre-mix through a sieve with a mesh size of at least 1.0 mm; e) drying the granulate at about 40-75°C until the desired loss on drying value in the range of 1-5 % is obtained; f) delumping the dried granulate; and g) adding lubricant to the granulate for final blending; wherein the diluents are selected from cellulose powder, dibasic calciumphosphate anhydrous, dibasic calciumphosphate dihydrate, erythritol, low substituted hydroxypropyl cellulose, mannitol, pregelatinized starch and xylitol; the binder is selected from copovidone (copolymerisates of vinylpyrrolidon with other vinylderivates), hydroxypropyl methylcellulose (HPMC), hydroxypropylcellulose (HPC), polyvinylpyrrolidon (povidone), pregelatinized starch, or low-substituted hydroxypropylcellulose (L-HPC); the disintegrant is selected from corn starch, crospovidone, low-substituted hydroxypropylcellulose (L-HPC) or pregelatinized starch; and the lubricant is selected from talc, polyethyleneglycol, calcium behenate, calcium stearate, hydrogenated castor oil or magnesium stearate; and wherein the DPP IV inhibitor is selected from a compound such as 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(R)-aminopiperidin-1-yl)-xanthine (linagliptin).
Patent NZ-615301-A (NZ)
Title: Pyrimidine derivatives for the treatment of viral infections
Inventor: RABOISSON PIERRE JEAN-MARIE BERNARD
IPC: C07D471/04
Filed: 2012-04-10
Abstract: Disclosed are 2-amino-5-(alkoxy/phenoxyl)-4-(5-amino)pyrimidine derivatives and analogues as represented by the general formula (I), or a pharmaceutically acceptable salt, tautomer, solvate or polymorph thereof, wherein R1 is hydrogen, alkyl, cyclopropyl, alkoxy, halogen, hydroxyl or trifluoromethyl; R2 is alkyl, alkoxyalkyl, cycloalkyl, heterocycle, aryl, bicyclic heterocycle, alkylaryl, heteroaryl and alkylheteroaryl, each of which is optionally substituted; R3 is alkyl, alkoxy, alkenyl or alkynyl, each of which is optionally substituted; and wherein the remaining substituents are as defined herein. Representative compounds include 2-amino-5-((3,4-dimethoxypyridin-2-yl)methoxy)-4-(hydroxyhexan-3-yl)amino)pyrimidine, 2-amino-5-methoxy-4-(hydroxyheptan-3-yl)amino)pyrimidine, and 2-amino-5-((3,4-dimethoxypyridin-2-yl)methoxy)-4-(butylamino)pyrimidine. Also disclosed is a pharmaceutical composition comprising a compound of formula (I) as defined above or a pharmaceutically acceptable salt, tautomer, solvate or polymorph thereof together with one or more pharmaceutically acceptable excipients, diluents or carriers, for use in the treatment of a disorder or disease in which the modulation of TLR7 and /or TLR8 is involved, and for the treatment of viral infections, such as hepatitis C virus.
Patent NZ-620422-A (NZ)
Title: Method for increasing the advantages of strength aids in the production of paper and paperboard
Inventor: KRAPSCH LUDWIG
IPC: D21H21/36
Filed: 2012-08-24
Abstract: Disclosed is a method for manufacturing paper, paperboard or cardboard comprising the steps of (a) pulping an aqueous cellulosic material containing a starch; (b) preventing at least a portion of the starch from being microbialiy degraded by treating the aqueous cellulosic material containing the starch with one or more biocides; and (h) adding a dry and/or wet strength polymer to the cellulosic material.
Patent NZ-626950-A (NZ)
Title: Bisarylsulfonamides useful in the treatment of inflammation and cancer
Inventor: FÄRNEGÅRDH KATARINA
IPC: C07C311/46
Filed: 2012-12-21
Abstract: A compound of formula (I), useful for the treatment of cancer, inflammation and inflammatory disorders, and a pharmaceutical composition containing the compound. An example of the compound is methyl 4-{ [(3-bromophenyl)sulfonyl]amino} -2-hydroxybenzoate.
Patent NZ-706963-A (NZ)
Title: Containers and methods for isolating liquids prior to dispensing
Inventor: DE CLEIR PIARAS VALDIS
IPC: B65D81/32
Filed: 2013-12-06
Abstract: Various attempts have been made to separate different liquid components from each other prior to dispensing. Existing separating mechanism can undesirably impede dispensing of the combined components, are susceptible to splashing, can result in limited functionality, or are only able to be used once. The present invention seeks to address these drawbacks amongst others by providing a container (100) for isolating first and second fluids, such as beverage concentrate components, until dispensing is provided, as well as methods of assembly and dispensing. The container can have first (111) and second (113) enclosed bodies for containing the first and second fluids to be dispensed and an insert (130) directing fluid from the enclosed bodies, such as toward one or more valves or separate discharge paths (148a, 148b).