baber/WOPTO huggingface dataset:
Patent UY-39507-A (UY)
Title: Construcciones polipeptídicas que se unen selectivamente a cldn6 y cd3
Inventor: CHRISTOPH DAHLHOFF
IPC: C12P21/08
Filed: 2021-11-08
Abstract: La presente invención se refiere a un polipéptido o a una construcción polipeptídica que comprende un dominio que se une a la claudina 6 (CLDN6) y otro dominio que se une a CD3. Así mismo, la invención proporciona un polinucleótido que codifica la construcción, un vector que comprende dicho polinucleótido y una célula huésped transformada o transfectada con dicho polinucleótido o vector. Además, la invención proporciona un procedimiento para producir la construcción de la invención, un uso médico de dicha construcción y un kit que comprende dicha construcción.
Patent YU-16001-A (YU)
Title: Pyrroloindoles, pyridoindoles and azepinoindoles as 5-ht2c agonists
Inventor: ADAMS DAVID REGINALD
IPC: A61K31/5517
Filed: 1999-09-01
Abstract: A chemical compound of formula (I), wherein n is 1, 2 or 3; R1 and R2 are independently selected from hydrogen and alkyl; R3 is alkyl; R4 to R7 are independently selected from hydrogen, halogen, hydroxy, alkyl, aryl, alkoxy, aryloxy, alkylthio, arylthio, alkylsulfoxyl, alkylsulfonyl, arylsulfoxyl, arylsulfonyl, amino, monoalkylamino, dialkylamino, nitro, cyano, carboxaldehyde, alkylcarbonyl, arylcarbonyl, aminocarbonyl, monoalkylaminocarbonyl, dialkylaminocarbonyl, alkoxycarbonylamino,aminocarbonyloxy, monoalkylaminocarbonyloxy, ialkylaminocarbonyloxy, monoalkylaminocarbonylamino and dialkylaminocarbonylamino, or R5 and R6 together form a carbocyclic or heterocyclic ring, and pharmaceutically acceptable salts and prodrugs thereof, and the use thereof in therapy, particularly for the treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders, diabetes insipidus, and sleep apnea, and particularly for the treatment of obesity.
Patent YU-22496-A (YU)
Inventor: STANLEY BORROMEO PETER
IPC: A61K38/12
Filed: 1996-04-05
Abstract: Obezbedjivanje farmaceutskih formulacija i postupaka za inhibiciju gljivične i parazitske aktivnosti korišćenjem jedinjenja formule I: gde je: R' je vodonik, metil ili NH2C(O)CH2-; R" i R"' su nezavisno metil ili vodonik; Rx1,Rx2,Ry1,Ry2, Ry3 i Ry4 su nezavisno hidroksi ili vodonik; R0 je grupa formule R1 je C1-C6 alkil, C1-C6 alkoksi, fenil, p-halofenil, p-nirofenil, fenoksi, benzil, p-halobenzil ili p-nitrobenzil; i R2 je neki acil bočni niz definisan ovde.
Patent YU-43197-A (YU)
Inventor: VOJIN PESOVIC
IPC: B05B17/06
Filed: 1997-10-31
Abstract: Pronalazak se odnosi na pulsator rucice tuša sa vibrirajućom lopticom koga čine cilindar (1), loptica (2), raspišivač (5) i disk (6). Na disku (6) se nalazi primarna mlaznica (3) kroz koju voda dolazi. Na raspršivaču (5) se nalaze kanali (12) kroz koje voda prolazi. U cilindru (1) se nalaze dve komore: komora loptice (9) i komora distributora (10). Njih povezuje sekundarna mlaznica (4). Pulsatorom se rešava problem dobijanja raspršenog pulsirajućeg mlaza vode pogodnog za kupanje tuširanjem ili tretmana hidromasažom. Pulsiranje se postiže bez pokretnih obrtnih elemenata. Suštinu čini slobodno postavljena loptica (2) u komoru (9). Raspršeni mlaz vode se dobija isticanjem kroz jednu centralnu mlaznicu (4). U komori loptice (9) prema sekundarnoj mlaznici (4) je smešten raspršivač (5) koji sprečava da loptica (2) sedne na mlaznicu (4) i zatvori protok. Pored toga raspršivač (5) ima ulogu da rasprši i uspori mlaz vode prilikom isticanja kroz mlaznicu (4), a time olakša prodor vazduha iz vakumskog prostora (13) do loptice (2). Pored mešanja vode i vazduha loptica (2) vibrira i proizvodi dopunsku pulsaciju vodenog mlaza.
Patent YU-54600-A (YU)
Title: Compositions with low irritancy
Inventor: ANN HALL-PUZIO PATRICIA
IPC: A61K8/34
Filed: 1999-03-02
Abstract: The present invention utilizes a polyethylene glycol diisostearate having an average degree of ethoxylation of from 40 - 100 as a component of a soap-based gel composition suitable for use in formulating stable cosmetic compositions, especially low irritancy deodorants.
Patent AT-A151799-A (AT)
IPC: F21Y115/10
Filed: 1999-09-02
Abstract: The invention relates to a lamp device which is worn on or directly in front of the forehead, respectively, or above or beside the eyes, respectively, and which ensures that the wearer's freedom of movement is neither restricted nor hindered by cables or other connections. The present invention is special in that several non-thermal, light-emitting elements are provided for the generation of light and that the individual light-emitting elements emit the light in a defined direction of radiation and are located in such a way that the light which is generated is directional. The light-emitting elements are located in such a way that each of them forms a particular angle with the visual axis of the wearer so that all light sources have a common intersection point just at the wearer's monitoring or working distance, respectively. Moreover, all individual light-emitting elements have the same distance to that intersection point. Furthermore, the vertical position of the area of illumination may be varied in front of the wearer's face.
Patent BE-822870-A (BE)
Title: CDC-IDC working cycle for combustion engines - has two expansion and contraction phases per cycle and two thermodynamic cycles
IPC: F02B1/06
Filed: 1974-12-03
Abstract: The CDC-IDC cycle denotes a two stroke system known as combustion during compression linked with injection during compression for a petrol engine motor. The working cycle comprises an expansion (1-2) at low pressure followed by a compression (2-3-4-5) to minimum volume. By the use of a buffer reservoir and second-stage fuel injection a sudden temperature rise from 140 deg.C to about 1300 deg.C, associated with a sudden pressure rise (5-6) after which the pressure falls approximately exponentially until the maximum volume is achieved (6-7) for the second time in the cycle, after which the system returns to the starting point.
Patent BE-894949-A (BE)
Title: Mounting for vibration type feed - has vertical column which supports upper and lower support surfaces
IPC: B65G27/08
Filed: 1982-11-08
Abstract: The mounting is for a vibration type feeding device. It has a base pedestal (10) with a top (11) connected directly to the base (3) of the feed device (1) to support it. There is also a lower support surface (12). Flexible supports on the lower support surface come in contact with a flat part or thrust zone. The pedestal can be one piece or made up of a number of pedestals forming the support surface supports. The flexible supports are made from plastic and flexible material.
Patent BE-898774-A (BE)
Title: Intermittent high pressure polymerisation e.g. of ethylene] - with introduction of catalyst into compression chamber
IPC: C08F10/02
Filed: 1984-01-27
Abstract: Process comprises feeding the substance to be polymerised in gaseous or vapour form to the working chamber of a compressor working volumetrically between two pressure stages, a catalyst controlling the polymerisation being present in the chamber at latest in the initial part of the expansion. - A pref. working sequence comprises (1) compression of the material to be polymerised, (2) polymerisation and expansion of the charge, (3) expulsion of the charge from the working chamber and (4) refilling with a fresh charge to be polymerised. - Polymerisation, esp. of ethylene, is carried out intermittently using a simple appts. and with very low energy consumption.(0/5)
Patent BE-901118-A (BE)
Title: Control for cable actuated bicycle brake - has pulley on one caliper arm to guide cable anchored to other arm
IPC: B62L1/16
Filed: 1984-11-23
Abstract: The control for cable actuated brakes has brake arms (1A,B) articulated around two pivots (2A,B) and controlled by a cable (3). A return pulley (11) is coupled to the brake blocks and is moved in response to a braking movement of the cable. It produces a control force proportional to but greater than that in the cable. - The pulley can be mounted on a lever (a) fixed to the caliper arm (A) and the cable end can be anchored on the other caliper arm. The cable ferrule (4) engages a stop (6) on the cable end anchor.
Patent BE-903332-A (BE)
Title: Werkwijze voor het bereiden van polyetheenfilms met hoge treksterkte en hoge modulus
IPC: C08J5/18
Filed: 1985-09-27
Abstract: Gladde, glanzende polyetheenfilms met hoge sterkte en modulus, en lage kruip, opaciteit en porositeit worden bereid door een 1-40 procentige oplossing van een polyetheen met Mw > 4 X 10 (5) in een vluchtig oplosmiddel bij hoge temperatuur om te zetten tot een film deze via thermoreversibele gelering om te zetten tot een gelfilm en deze bij verhoogde temperatuur ultrahoog, uniaxiaal te verstrekken. Met deze werkwijze is het mogelijk films te bereiden met moduli boven 50 GPa, opaciteit beneden 10 % en waterdampdoorlaatbaarheid beneden 0,5, die vrijwel geen kruip vertonen en een glad en glanzend oppervlak bezitten.
Patent BE-780418-A (BE)
Title: Vinyl chloride suspension polymn - using alkaline aqs phase to prevent deposition of polymer on reactor walls
IPC: C08F14/06
Filed: 1972-03-09
Abstract: Suspension polymerisation of vinyl chloride mixed with a smaller amount of another monomer, is effected in an aqs. medium contg. a small amount of a suspension agent and a polymsn. initiator, a small amount of an alkaline substance being added to the polymsn. medium before the intiation of polymsn., or before the degree of conversion reaches 30%, so that the pH value of the aqs. phase is >=8.
Patent BE-785099-A (BE)
Title: Control rod assembly - for fast neutron reactor with rising cooling gas flow
Inventor: YELLOWLEES J M
IPC: G21C7/10
Filed: 1972-06-19
Abstract: The control rod moves in a reciprocating motion in a double walled casing whose cavity is under vacuum and whose inner wall forms the channel for the rod. The rod itself, driven by an actuator mechanism below the core, consists of an upper absorber section, consisting of plates of boron carbide, through which are cooling channels leading from an intermediate gas plenum below which is a reflector section of tubes filled with alumina pellets. With a reactor whose coolant inlet/outlet temps. are ca 250/650 degrees C, the rod absorber section temp. is kept 350 degrees C so preventing overheating and deformation.
Patent CA-1113769-A (CA)
Title: Foods and processes
Inventor: SCHARA ROBERT E
IPC: A23K20/105
Filed: 1972-06-16
Granted: 1981-12-08
Abstract: ABSTRACT OF THE DISCLOSURE   Infestation of intermediate moisture foods is prevented by the incorporation of a small but effective amount of an alkane-diol.
Patent CA-1047538-A (CA)
Inventor: MANGIN HENRI
IPC: C07C27/26
Filed: 1974-07-26
Granted: 1979-01-30
Abstract: ABSTRACT OF THE DISCLOSURE:           The present invention is concerned with a process for the manufacture of crystallised sorbitol, which comprises conti-nuously mixing molten sorbitol, having a content of dry matter of more than 90% and being in a sub-divided form, for example in the form of droplets, globules, bundles, jets, layers or sheets with 20 to 80% by weight of sorbitol in the form of fine powder.   The mixing is carried out inside an open  rotating receptacle with the axis of rotation preferably being inclined to the horizontal plane, at the surface of the mixture set in motion by the rotation of the receptacle.  The process according to the invention enables to obtain crystallized sorbitol in a stable form at the best cost price.
Patent CA-1059577-A (CA)
Inventor: ADAMO RALPH J
IPC: G03G5/10
Filed: 1974-09-17
Granted: 1979-07-31
Abstract: ABSTRACT OF THE DISCLOSURE           Disclosed is an improved xerographic belt.  The belt comprises an endless, flexible, seamless sheet of a ductile metal having a photoconductive layer on the outer surface thereof with a protective coating of an adhesive polyester thermoplastic resin along one or both of its edges.
Patent CA-1045567-A (CA)
Inventor: HAUPT HEINZ
IPC: G01N33/574
Filed: 1975-03-11
Granted: 1979-01-02
Abstract: Abstract of the disclosure?       The present invention relates to a derivative of the alpha1-fetospecific serum protein and to a process for pre-paring it from a solution containing alpha1-fetospecific protein by treating it with neuraminidase and then isolating it by electrophoresis.
Patent CA-1048544-A (CA)
Inventor: LASCO RALPH H
IPC: B01J27/00
Filed: 1975-04-07
Granted: 1979-02-13
Abstract: ABSTRACT OF THE DISCLOSURE         An economical process is described for the oxidation of allylacetone to 2,5-hexanedione in a mixed solvent system, using palladium chloride catalyst in the presence of copper chloride and oxygen.  Through the use of high copper/palladium mole ratios together with copper/allylacetone mole ratios greater than 1, high yields of product are obtained with minimal losses of palladium.
Patent CA-1039577-A (CA)
Inventor: FIEGL DAVID E
IPC: B61F5/32
Filed: 1975-04-15
Granted: 1978-10-03
Abstract: ABSTRACT OF THE DISCLOSURE           Railway truck side frame having a pedestal jaw roof containing a flat wear plate within a contained area which will shift the burden of wear elsewhere.  The contained area is provided by vertical, longitudinally extending, peripheral lips on each side of the pedestal roof between the downstanding sidewalls.  The flat wear plate is secured to the pedestal roof with a weldment at the side surfaces of the plate, the weldment extending substantially the length of the plate and, downwardly, the weldment extending no lower than the vertical peripheral lips.
Patent CA-1070203-A (CA)
Inventor: DICICCO TRIPOLI J
IPC: A61B17/14
Filed: 1975-07-30
Granted: 1980-01-22
Abstract: ABSTRACT An ear piercing gun is arranged for simultaneously piercing an ear and driving a decaratively headed wire stud into a spring clip retaining nut to form an "ear-ring",  Relatively movable first and second jaws releasably hold said nut and stud respectively in registration with an ear lobe there-between and a plunger and the second jaw is movable under spring bias, re-leased by a trigger, to drive the stud through the ear lobe into said nut as said jaws move together.
Patent CA-1067846-A (CA)
Inventor: FRANZ WILLIAM F
IPC: C07C2/62
Filed: 1975-08-29
Granted: 1979-12-11
Abstract: SULFURIC ACID ALKYLATION PROCESS         (D#73,933-F) A B S T R A C T        A process for alkylating isoparaffin hydrocarbons with olefin hydrocarbons for production of high octane gasoline range alkylate wherein the alkylation reaction is performed in the presence of a sulfuric acid alkylation catalyst containing from about 0.0005 to about 0.5 weight percent of a selected micelle forming amphiphilic compound, and wherein the reaction is carried out in a non-backmixed tubular reactor.     -I-
Patent CA-1064737-A (CA)
Title: Copper base alloys and processing same
Inventor: SHAPIRO STANLEY
IPC: C22F1/08
Filed: 1975-10-03
Granted: 1979-10-23
Abstract: ABSTRACT OF THE DISCLOSURE Copper base alloys are processed to obtain improved stress corrosion resistance especially for use in severe ammoniacal environments;  the process comprises providing a copper base allby consisting essentially of from 1.0 to 4.?% silicon, from 1.0 to 5.0% tin, balance copper, wherein the total silicon plus tin content is at least 3.5%; hot rolling the alloy at a starting temperature in excess of 650°C and within 50°C if the solidus temperature of the alloy, and with a finishing temperature in excess of 400°C; cold rolling the alloy at a temperature below 200°C; and annealing the alloy at a temperature of from 250 to 850°C for from 10 seconds to 24 hours.
Patent CA-1074448-A (CA)
Inventor: NEUNER JAMES A
IPC: G21C17/00
Filed: 1975-11-04
Granted: 1980-03-25
Abstract: ABSTRACT OF THE DISCLOSURE Electrical communication means for transmitting an analog signal generated at a first location to a remote second location which maximizes noise rejection uses analog to digital converters to sample the analog signal with a periodicity equal to an integral number of cycles of the transmission line frequency.  At the receiving end, a summing unit receives the digital output and maintains a running digital sum.  Upon receipt of a reset input, the sum is transmitted and cleared from the summing unit.  The transmitted digital sum is shifted and the least significant bit dropped.  A random access memory stores the transmitted sum while a counter cycles through its output states at the sampling frequency.  A decoder responsive to a given output state of the counter provides an output which is transmitted to the reset input of the summing unit.  A strobe input readies the random access memory to accept the trans-mitted sum and a second counter counts the decoder output and cycles through its output states which are also trans-mitted to the random access memory to identify the location within the random access memory that the transmitted sum is to assume.
Patent CA-1063804-A (CA)
Inventor: IEDA MICHAEL
IPC: A63H17/26
Filed: 1976-01-08
Granted: 1979-10-09
Abstract: ABSTRACT OF THE DISCLOSURE           A breakaway type toy vehicle has a chassis and a body which is removably mounted thereon.  The body includes a plurality of body elements each of which is releasably connected to at least one other body element.  Impact responsive means are provided in the vehicle for propelling one of the body elements away from the vehicle's chassis upon an impact therewith.  The propulsion of this one body element causes sequential breakaway of the body elements from the chassis as the first propelled body element draws with it the body element to which it is connected.
Patent CA-1065323-A (CA)
Inventor: MILLER GEORGE A
IPC: C07D233/91
Filed: 1976-02-03
Granted: 1979-10-30
Abstract: ABSTRACT   This disclosure describes novel aralkyl imidazoles, their acid addition salts, their metal salt complexes and processes for their preparation.  These compounds possess biological activity and in particular are useful as systemic protectant/eradicant fungicidal agents for controlling plant diseases caused by fungi and as plant growth regulators.  The metal complex salts of these compounds are particularly useful in their ability to reduce undesirable plant growth regulatory activity and phytotoxicity while retaining their ability for controlling platn diseases caused by fungi.  The above-mentioned aralkyl imidazoles have the structural formula:    wherein Z is a phenyl, naphthyl, biphenyl, acenaphthenyl, indanyl, indolyl, pyridyl, pyrimidyl, pyrryl, furyl or thienyl group, said group being either unsubstituted or substituted with 1 to 3 substituents selected from the group consisting of (C1-C4) alkyl, methoxy, ethoxy, chloro, fluoro, bromo, iodo, nitro, amino and methylthio:          R1 is hydrogen, (C1-C10) alkyl, (C2-C12) alkenyl, (C7-C9) aralkyl which is either unsubstituted or substituted with 1 or 2 substituents selected from the group consisting of (C1-C4) alkyl, methoxy, ethoxy, chloro, fluoro, bromo, iodo, nitro, amino and methylthio, a phenyl group which is either unsubstituted or substituted with 1 or 2 substituents selected from the group consisting of (C1-C4) alkyl, methoxy, ethoxy, chloro, fluoro, bromo, iodo, nitro, amino and methylthio, (C3-C7) cycloalkyl or (C5-C7) cycloalkenyl; R2 is (C1-C10) alkyl, (C2-C12) alkenyl, (C7-C9) aralkyl which is either unsubstituted or substituted with 1 or 2 substituents selected from the group consisting of (C1-C4) alkyl, methoxy, ethoxy, chloro, fluoro, bromo, iodo, nitro, amino and methylthio,  a phenyl group which is either unsubstituted  or substituted with 1 or 2 substituents selected from the group consisting of (C1-C4) alkyl, methoxy, ethoxy, chloro, fluoro, bromo, iodo, nitro, amino and methylthio, (C3-C7) cycloalkyl or (C5-C7) cycloalkenyl; or R1 and R2 taken together form (C3-C8) cycloalkyl; A and B are divalent (C1-C5) alkylene groups; X is (C1-4) alkyl, halogen or nitro; a is 0 to 3; n is 0 or 1; n' is 0 or 1; and n plus n' is 1 or 2; provided that when Z is unsubstituted phenyl, R1 is hydrogen, A is methylene and n' is 0, then R2 is (C4-C10) alkyl, C2-C12) alkenyl, (C7-C9) aralkyl which is either unsubstituted or substituted with 1 or 2 substituents selected from the group consisting of C1-C4) alkyl, methoxy, ethoxy, chloro, fluoro, bromo, iodo, nitro, amino and methylthio, a phenyl group which is either unsubstituted or substituted with 1 or 2 substituents selected from the group consisting of (C1-C4) alkyl, methoxy, ethoxy, chloro, fluoro, bromo, iodo, nitro, amino and methylthio, (C3-C7) cycloalkyl or (C5-C7) cyclo-alkenyl; and acid addition salts thereof.
Patent CA-1070638-A (CA)
Inventor: FUJITA SHIGERU
IPC: C25D3/24
Filed: 1976-03-01
Granted: 1980-01-29
Abstract: ZINC  PLATING  METHOD                 ABSTRACT OF THE DISCLOSURE    An article is zinc plated by electrodeposition in an alkaline zinc plating bath of ZnO and NaOH to which has been added, optionally together with a small quantity of an aromatic aldehyde, a polyamine sulfone represented by the general formula   where:  each of R1 and R2 is hydrogen, an allyl group, a straight-chain or branched-chain alkyl group having 1 to 16 carbon atoms, an aralkyl group, or a hydroxyalkyl group of the general formula  , where m is an integer of 1 to 6; X- is a halogen ion, HSO4-, HSO3-, HCOO-, or CH3COC-; and n is an integer such that the number average molecular weight becomes 2,000 to 350,000. a and b are natural numbers having a relation such that a:b = 100: (10 to 100).
Patent CA-1037206-A (CA)
Inventor: MESSMER HEINZ
IPC: A47K11/04
Filed: 1976-04-30
Granted: 1978-08-29
Abstract: ABSTRACT OF THE DISCLOSURE         The invention relates to toilets for children such as children's chamber pots, night stools, seats for toilet bowls, travelling chamber pots, or the like.  In accordance with the invention, such toilets include a tray or receptacle for accommodating a package, roll or the like of all purpose towels, a deodorant dispenser or other toilet articles.  The tray or receptacle is disposed at the back of the toilet out of reach of the child using it.  It is also contemplated to mount accessories, such as a handlebar or steering wheel, at the front of the toilet.
Patent CA-1043630-A (CA)
Inventor: THEURER JOSEF
IPC: E01B27/12
Filed: 1976-06-17
Granted: 1978-12-05
Abstract: Abstract of the Disclosure A mobile ballast tamper comprises a vertically movable tamping head with vibratory tamping tools for tamping ballast under the ttack ties whereby the track is pressed upwardly.  A couterpressure beam for holding the track in position against the upward pressure extends above each track rail in the direction thereof in the region of the tamping tools and has at least three points of engagement with the associated rail.  Power-actuated drives are linked to ends of the couterpressure beams.
Patent CA-1081910-A (CA)
Title: Product containing alumina trihydrate and a source of  b.sub.2o.sub.3 and method
Inventor: MOORE GREGORY R
IPC: C09K21/02
Filed: 1976-06-18
Granted: 1980-07-22
Abstract: ABSTRACT OF THE DISCLOSURE       The ASTM E84 flamespread of fibrous products such as hardboard is reduced by incorporation of a com-bination of alumina trihydrate and a source of B2O3, such as boric acid.  The B2O3 source should be capable of pro-viding B2O3 at a temperature below 400°C.
Patent CA-1074323-A (CA)
Inventor: ROVNYAK GEORGE C
IPC: C07D495/04
Filed: 1976-07-27
Granted: 1980-03-25
Abstract: Abstract Anti-inflammatory activity is exhibited by com-pounds having the formula   the salts thereof and the 5-oxide and 5,5-dioxide thereof, wherein R1 is hydrogen, alkyl, aryl, arylalkyl, or    wherein X is alkyl or aryl; and R2 and R3 are the same or different and are hydrogen, alkyl, hydroxy, alkoxy, alkylthio, alkylsulfinyl, trifluoromethyl, halogen,  , cyano, nitro or dialkylamino; wherein the terms alkyl and alkoxy refer to groups having 1 to 8 carbon atoms and the term aryl  refers to phenyl or phenyl monosubstituted with an alkyl, alkoxy, halogen or trifluoromethyl group.