baber/WOPTO huggingface dataset:
Patent ZA-901320-B (ZA)
Title: Compositions for the treatment of microbial infections
Inventor: WHITE GEOFFREY
IPC: A61K31/635
Filed: 1990-02-21
Abstract: A composition comprising the compounds 2,4-diamino-5-(8-dimethylamino-7-methyl-5-quinolylmethyl)pyrimidine and sulphadimethoxine or salts- thereof useful for treating bacterial infections in small domestic animals.
Patent ZA-903139-B (ZA)
Title: Derivatives of 4-phenylmethyl-1h-indole,process and intermediates of preparation,application as medicaments and compositions containing them
Inventor: CLEMENCE FRANCOIS
IPC: A61K31/40
Filed: 1990-04-25
Abstract: The invention relates to the products of general formula (I): 
<IMAGE>
 in which:
 R and R1, which may be identical or different, represent, in particular, H, alkyl, alkenyl or alkynyl, cycloalkyl or arylalkyl, optionally substituted, or, together, form a heterocycle which can contain a second heteroatom O, S or N, optionally substituted,
 A represents:
 (CH2)n with n = 2, 3, 4 or 5, or 
<IMAGE>
 X, Y, which may be identical or different, are H or OH or, together, form an oxo function,
 a, b, c, d are H or, together, form an oxo function or a double bond,
 Z represents, in particular, H, alkyl, alkenyl or alkynyl, cycloalkyl or arylalkyl, optionally substituted, or Z represents -R2-N(R3)(R4) where R2 is alkylene and R3 and R4 are R1 and R2 except for alkenyl and alkynyl,
 in all the possible isomeric forms and in the form of addition salts with inorganic or organic acids.
Patent ZA-907300-B (ZA)
Title: Bile acid derivatives,processes for their preparation,and use as pharmaceuticals
Inventor: KRAMER WERNER
IPC: C07D213/81
Filed: 1990-09-13
Abstract: Bile acid derivatives of the formula I  W-X-G in which G is a bile acid residue, W is an active substance portion of a medicament and X is a linker between bile acid residue and active substance portion, are outstandingly suitable for introducing active substances into the enterohepatic circulation. The compounds I are absorbed and enter the bloodstream. This makes it possible by utilising the natural reabsorption of the bile acids to improve the absorption of drugs which are absorbed with difficulty, if at all. W can be, for example, a peptide, an antibiotic, an antiviral substance, an anticancer agent, a liver protective, an antihyperlipidaemic, a diuretic, an agent to lower blood pressure, a renin inhibitor, a substance to treat cirrhosis of the liver or a substance for treating diabetes. G is a bile acid residue in the form of the free, natural or chemically modified acids, the esters and amides, the salt forms and forms derivatised on alcohol groups. X is a large number of intermediate members or else a bond.
Patent ZA-913359-B (ZA)
Title: Stabilization of somatotropins and other proteins by modification of cysteine residues
Inventor: BUCKWALTER BRIAN LEE
IPC: C07K14/555
Filed: 1991-05-03
Abstract: The present invention relates to physiologically-active derivatized natural and recombinant mammalian and human proteins and polypeptides. The invention provides chemical methods for derivatizing natural and recombinantly-derived proteins or polypeptides containing cysteine residues, either naturally or through site specific mutageneses. The pharmaceutical compositions containing said derivatized proteins and/or polypeptides are formulated to provide stable, long-acting compositions of such proteins and/or polypeptides, previously difficult to achieve.
Patent ZA-915273-B (ZA)
Title: Delivery system with a protective sleeve
Inventor: MAGRUDER JUDY A
IPC: A61M31/00
Filed: 1991-07-08
Abstract: This invention relates to an active agent delivery device. More particularly, the invention relates to a delivery device that includes a sleeve to protect the delivery device from transient mechanical forces. The delivery device of the invention is robust and resistant to transient mechanical forces. The invention provides a fluid-imbibing delivery device comprising a housing enclosing an internal compartment, said housing having a first wall section that substantially restricts the passage of fluid into the delivery device, i.e. is substantially fluid-impermeable, and that contains a beneficial agent; a second wall section that permits the passage of fluid into the delivery device, i.e. is fluid-permeable, and that contains at least one expandable driving member; and exit means; with a protective sleeve means extending from the first wall section of the housing to cover and protect the second wall section of the housing and the junction of the first and second sections. The protective sleeve is preferably configured to provide substantially no resistance to flow of fluid or fluid vapors through the fluid-permeable second wall section.
Patent ZA-926535-B (ZA)
Title: Synergistic combinations of iodopropargyl compounds with 1,2-benzisothiazolin-3-one in controlling fungal and bacterial growth in aqueous fluids
Inventor: OPPONG DAVID
IPC: A01N47/12
Filed: 1992-08-28
Abstract: Synergistic combinations of iodopropargyl compounds and 1,2-benzisothiazolin-3-one for use in controlling the growth of at least one microorganism, such as fungi and bacteria in aqueous fluids, such as metalworking fluids.
Patent ZA-934583-B (ZA)
Title: Imidazolyl-substituted cyclohexane derivatives
Inventor: MUELLER ULRICH E
IPC: C07D233/68
Filed: 1993-06-25
Abstract: Imidazolyl-substituted cyclohexane derivatives are prepared by reaction of corresponding cyclohexane derivatives with substituted imidazoles and subsequent variation of the substituents. The imidazolyl-substituted cyclohexane derivatives can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.
Patent ZA-952287-B (ZA)
Title: Process for preparing (1H-tetrazol-5-yl)tetrazolo [1,5-a] quinolines and naphthyridines
Inventor: OLMSTEAD KAY K
IPC: C07D471/14
Filed: 1995-03-20
Abstract: A process according to reaction scheme (I), wherein n is 0, 1 or 2, R is C1-4 alkyl, C1-4 alkoxy, halogen, methylmercapto, methylsulfonyl, or two R's can be combined as methylenedioxy; B is either nitrogen or CH; and X is a suitable leaving group; M is a lower alkali metal cation; with the proviso that, when R is methylmercapto or methylsulfonyl, then n must be 1.
Patent ZA-952847-B (ZA)
Title: Apparatus for holding a toolholder shank
Inventor: ERICKSON ROBERT A
IPC: B23B31/107
Filed: 1995-04-06
Abstract: An apparatus for releasably holding a tubular toolholder shank by axially reciprocating a lock rod between a locked and unlocked position. The lock rod is reciprocated using a rotatable cam. The cam compresses a spring thereby urging the lock rod in the locked position and positively displaces the lock rod to the unlocked position.
Patent ZA-963939-B (ZA)
Title: Diaryldiamine derivatives
Inventor: DONDIO GUILIO
IPC: C07C237/42
Filed: 1996-05-17
Abstract: PCT No. PCT/EP96/02152 Sec. 371 Date Nov. 18, 1997 Sec. 102(e) Date Nov. 18, 1997 PCT Filed May 20, 1996 PCT Pub. No. WO96/36620 PCT Pub. Date Nov. 21, 1996A compound, or solvate or salt thereof, of formula (I) in which, R1 and R2, are, independently hydrogen, linear or branched C1-6 alkyl, C3-7 cycloalkyl, C3-7 cycloalkenyl, or C3-6 alkenyl, or together form a C3-7 alkyl; R3 and R4 are, independently, hydrogen, linear or branched C1-6 alkyl, or R4 is oxygen forming with the carbon atom to which is attached a C=O group; R5 is hydrogen, hydroxy, or C1-3 alkoxy; R6 is halogen, NH2 or a para or meta -COR-8 group, in which R8 is C1-8-alkyl, C1-8-alkoxy or NR9R10, wherein R9 and R10, are, independently, hydrogen, straight or branched C1-6 alkyl, C3-7 cycloalkyl or phenyl; or R6 is a para or meta group in which R11 and R 12 are, independently, hydrogen or straight or branched C 1-6 and, R7 is hydrogen, or straight or branched C1-8 alkyl; is provided. The present compound is useful as a delta opiod modulator.
Patent ZA-968398-B (ZA)
Title: Gel formulations containing growth factors.
Inventor: CINI JOHN
IPC: A61K38/27
Filed: 1996-10-04
Abstract: Gel formulations containing polypeptide growth factors having human mitogenic or angiogenic activity are provided. The gel formulations are useful for topical or incisional wound healing for cutaneous wounds, particularly in the anterior chamber of the eye. The gel formulations also comprise a water soluble, pharmaceutically or ophthalmically compatible polymeric material for providing viscosity within various ranges determined by the application of the gel. The gel formulations provide controlled release and increased contact time of the growth factor to the wound site.
Patent ZA-972457-B (ZA)
Title: Antiperspirant stick composition
Inventor: KASAT RADHAKRISHNA B
IPC: A61K8/34
Filed: 1997-03-20
Abstract: Disclosed are antiperspirant stick compositions that exhibit substantially no visible residue (whitening) upon application to the skin or after drying. The compositions include both emollients that are silicone materials and emollients that are not silicone materials, these materials having a refractive index of at least 1.4460, in addition to including a vehicle (for example, cyclomethicone), a gelling agent (for example, stearyl alcohol and hydrogenated castor oil) and the active antiperspirant material (for example, particulate antiperspirant metal salts). These compositions reduce the necessity of using expensive silicone materials, while still achieving antiperspirant compositions with substantially no visible residue.
Patent ZA-972746-B (ZA)
Title: Novel 2,3-benzodiazepine derivatives
Inventor: ISTVAN LING
IPC: A61K31/551
Filed: 1997-04-01
Abstract: Mono- or di-halo substituted 2,3-benzodiazepine derivatives of formula (I), their isomers and acid addition salts are new. R1, R2 = H, halogen, 1-4C alkyl, 1-4C alkoxy, nitro, CF3 or NR8R9; R3 = 1-4C alkyl, 3-5C cycloalkyl or COR13; R4, R5 = H or 1-3C alkyl; R6, R7 = H, Cl or Br, provided that not both are H at the same time; R8, R9 = H, 1-4C alkyl or COR10; R10, R13 = H, optionally substituted 1-6C alkyl, 6-10C aryl, 1-4C alkoxy, 3-5C cycloalkyl, 2-6C alkenyl, 3-5C cycloalkoxy or NR11R12; and R11, R12 = H, 1-4C alkyl, 3-5C cycloalkyl or 6-10C aryl.
Patent ZA-979412-B (ZA)
Title: Triglyceride fat crystallization
Inventor: LANSBERGEN GABRIEL JACOBUS T
IPC: A23D9/00
Filed: 1997-10-21
Abstract: Saturated triglycerides which have a big difference in chain length between the longest and the shortest fatty acid chain and which are able, when incorporated in a small amount into a slow crystallizing fat, particularly a low-trans fat, to increase considerably the speed of crystallization.
Patent ZA-993249-B (ZA)
Title: Process for the preparation of pulverulent heterogeneous substances.
Inventor: FOERSTER MARTIN
IPC: C01B13/34
Filed: 1999-05-11
Abstract: A powdered heterogeneous substance is produced by treating a dispersion, suspension or emulsion in a turbulent or laminar burner under specified conditions, feeding the reaction mixture into a tube where it is further treated and then feeding it to a scrubber, separator or filter for further treatment.
Patent AT-409990-B (AT)
Inventor: MACULAN ALEXANDER DIPL ING DR
IPC: E01C5/14
Filed: 2000-04-05
Granted: 2002-12-27
Abstract: The kit has three types of flooring element, which are each formed from support beams (1) and spaced floorboards (2) fixed to the support beams by joints (3). The first type is square with floorboards parallel to the sides (s). The second and third types are formed as a right angle triangle, whose short sides (k1,k2) are the same length as the side of the first type, with the floor boards parallel to a first or a second short side, respectively.
Patent GB-2363635-B (GB)
Title: Method of introducing additives in steelmaking
Inventor: BRAY STEPHEN DAVID
IPC: C21C7/04
Filed: 2000-09-18
Granted: 2002-11-27
Abstract: The additives, in particulate solid form, are conveyed pneumatically in a divergent stream from a pneumatic gun to impinge upon the molten iron and mix therewith. The gun is spaced above a surface of molten iron such that the pneumatically conveyed stream including the additive has a central axis which is either horizontal (or at an acute angle to the horizontal). The gun is prefereably adjustable for adjustment of the stream angle, and the stream may be either added to pouring metal or to cover a surface of the molten iron.
Patent GB-2369308-B (GB)
Title: Particle manipulation device
Inventor: CEFAI JOSEPH
IPC: B01D51/08
Filed: 1998-07-22
Granted: 2002-11-06
Abstract: A device for performing the manipulation of particles suspended in a fluid is disclosed. The device comprises a duct for the flow of a fluid in which particles are suspended, an acoustic transducer, and a reflector for establishing an acoustic standing wave field across the width of the duct. It has been unexpectedly found that optimum performance of the device occurs when the spacing between the transducer and a reflector is 300 microns or less. The device seeks to overcome prior engineering difficulties that prevented one from observing the individual particle bands or separating the individual particle bands from the duct.
Patent GB-2375113-B (GB)
Title: A modified, oncolytic, non-laboratory HSV strain and its use in treating cancer
Inventor: COFFIN ROBERT STUART
IPC: A61K39/00
Filed: 2001-01-22
Granted: 2004-10-20
Abstract: The present invention relates to the use of a modified, oncolytic, herpes simplex virus (HSV) strain in the manufacture of a medicament for the oncolytic treatment of cancer, which HSV strain: 
(a) has a greater ability than HSV1 17+, HSV1 F and HSV1 KOS strains with equivalent modifications to replicate in or kill tumour cells; and 
(b) is obtainable by isolating an HSV strain from a host and modifying the isolated HSV strain to provide for selective replication in tumour cells.
Patent GB-2402302-B (GB)
Title: Communications systems and methods
Inventor: BAKER DAVID
IPC: H04L45/02
Filed: 2003-05-28
Granted: 2005-08-31
Abstract: An ultra-wideband (UWB) home wireless network comprises a plurality of UWB devices each forming a node of the network, pairs of UWB devices being configured for bidirectional communication using one of a plurality of UWB channels. A device controller stores connection data in a connection table for forwarding incoming data packets to further devices using multiple hops. Each packet contains channel identification data used by a node to determine a channel for forwarding the packet. The controller may have a separate control and data bus. A new device initiated to the network broadcasts an alert to other devices. A response causes the new device to modify its device identifier since this identifier is already in use.
Patent GB-2047093-B (GB)
Title: Controlled release compositions
IPC: A61K9/22
Filed: 1980-03-21
Granted: 1983-12-07
Abstract: A controlled release composition comprising a prostaglandin and a polymeric carrier therefor comprising residues having a ratio of number average molecular weight to functionality greater than 1,000 which comprise polyethylene oxide and are cross-linked through urethane groups.
Patent GB-2144764-B (GB)
Title: Liquid detergent compositions
Inventor: HUGHES LARRY JAMES
IPC: C11D1/12
Filed: 1984-08-06
Granted: 1987-07-22
Abstract: Heavy-duty liquid detergents containing sulfonate and alcohol ethoxylate sulfate anionic surfactants, ethoxylated nonionic surfactant, optional quaternary ammonium, amine or amine oxide surfactants, saturated fatty acid, polycarboxylate builder, a neutralization system comprising sodium, potassium and preferably low levels of alkanolamines, and a solvent system comprising ethanol, polyol and water. The compositions are isotropic liquids providing a high level of detergency performance and improved chlorine bleach compatibility.
Patent GB-2174029-B (GB)
Title: Improvements in or relating to outlet valves for melt-containing vessels
Inventor: MONKS JAMES
IPC: B22D41/18
Filed: 1986-03-24
Granted: 1988-07-06
Abstract: The invention provides an outlet valve for a melt-containing vessel comprising a lower insert piece mounted in the base of the vessel having an outlet bore passing therethrough from the inside to the outside of the vessel, an elongate shaft located above and pressed down upon the lower insert piece, the shaft having a lower face mating with an upper face of the lower insert piece, the shaft being rotatable relative to the lower insert piece about a generally vertical axis, the bore through the lower insert piece being offset, at least at its upper end, from the axis of rotation, and the shaft having a side opening at the lower end thereof capable of aligning with the top of the bore through the lower insert piece in at least one rotational position.
Patent GB-2174846-B (GB)
Title: Attenuation of microwave signals
Inventor: CARTWRIGHT NORMAN EDWIN
IPC: H01Q17/00
Filed: 1986-04-23
Granted: 1990-01-17
Abstract: It is sometimes necessary to reduce the power of microwave transmissions, e.g. to avoid overloading a receiver or to reduce a transmitter's potential to cause interference. The invention reduces the power by inserting radiation absorbent material (14) into the aperture of the antenna (10). In the preferred embodiment a membrane of absorbent plastics is stretched across the aperture of the dish reflector.
Patent GB-2203556-B (GB)
Title: Two-wire loop electric circuit arrangement
Inventor: WILLIAMS TIMOTHY DAVID NEIL
IPC: G08C19/02
Filed: 1987-04-06
Granted: 1991-04-17
Abstract: The circuit includes a loop (3) in which a signal current flows; a supply voltage generation circuit (1); a signal conversion circuit (2); a switch (5) operative to connect either the supply voltage generation circuit or the signal conversion circuit into the loop (3) at any instant, the outputs of the supply voltage generation circuit and the signal conversion circuit being supplied to a common load (4) which controls operation of the switch (5); and a pair of capacitors (6,7) connected across the outputs of the supply voltage generation circuit and the signal current conversion circuit, respectively.
Patent GB-2200649-B (GB)
Title: Dual-cure dental cement
Inventor: WALTON IAN GEOFFREY
IPC: A61K6/00
Filed: 1988-01-28
Granted: 1990-07-11
Abstract: The compositions of this invention posses both calcium hydroxide cement characteristics and light cure characteristics and hence strong bonds are likely to form with both the tooth and conventional filling materials. There is less likelihood that a filling may fall out of a cavity. The present invention provides a two component composition which comprises a first component comprising an ethylenically polymerizable compound which contains both a salicylate group and at least one acrylate, alkacrylate, acrylamide or alkacrylamide group and second component comprising calcium hydroxide or a suitable precursor to calcium hydroxide.
Patent GB-2235686-B (GB)
Title: Process for producing an inorganic biomaterial
Inventor: KASUGA TOSHIHIRO
IPC: A61K6/838
Filed: 1990-06-20
Granted: 1993-04-14
Abstract: The present invention relates to a process for producing an inorganic biomaterial, according to which, there can be obtained an inorganic biomaterial excellent in strength and biocompatibility, having a structure in which portions constituted by crystallized glass or crystals of calcium phosphate excellent in bioactivity are dispersed in a skeleton or matrix constituted by crystals of partially stabilized zirconia and/or alumina showing high strength. Accordingly, the inorganic biomaterial is very useful as biomaterial for artificial bones, dental implants, etc.
Patent GB-2239797-B (GB)
Title: Medicaments containing as active substance sulphur-containing carboxylic acids and their use in combatting retroviruses
Inventor: KALDEN JOACHIM
IPC: A61K31/385
Filed: 1990-11-08
Granted: 1994-06-15
Abstract: Pharmaceutical compositions containing at least one compound of the formula I <IMAGE> in which X is a hydrogen atom or the two Xs denote a single bond between the two sulphur atoms; Y is hydrogen or C1-C6-alkyl and n is a number from 1 to 10, or the therapeutically utilisable salts thereof, excepting  alpha -lipoic acid and dihydrolipoic acid, characterised in that the dosage unit for solid or semisolid compositions contains 20 mg to 6 g, in particular 50 mg to 2 g, preferably 100 mg to 1 g, of total amount of agent I, or in that they take the form of solutions, suspensions or emulsions which contain 0.2 mg to 800 mg per ml, preferably 10 mg to 500 mg, in particular 40 mg to 200 mg per ml of total amount of agent I or a pharmaceutically utilisable salt thereof, and processes for the preparation thereof.
Patent GB-2298465-B (GB)
Title: A selector mechanism for a vehicle transmission
Inventor: BEADLE DAVID EDWARD
IPC: F16H59/02
Filed: 1994-10-31
Granted: 1997-10-29
Abstract: A selector mechanism (11) for a vehicle transmission comprising an automatic transmission (124) coupled to a range-change transmission (128) having first and second ranges includes a ratio selector lever (56) movable along three paths (14, 18, 20) defined by a gate (12). The first path (14) is defined by a first limb of the gate (12) for shift selection in the automatic transmission (124) with the first range of the range-change transmission (128) selected. The second path (20) is defined by a second limb of the gate (12) substantially parallel with the first limb for shift selection in the automatic transmission (124) with the second range of the range-change transmission (128) selected and the third, transverse, path (18) is defined by a limb of the gate (12) transverse to the first and second limbs. Movement of the selector lever (56) along the transverse path (18) effects a change from one range to the other in the range-change transmission (128).
Patent HU-212629-B (HU)
Title: Shaping composition based on inorganic sintering material, process for producing and using thereof
Inventor: BAYER MICHAEL
IPC: C08K3/00
Filed: 1992-06-16
Abstract: In a ceramic or powder-metallurgical molding composition which contains waxes as binders, the addition of an ethylene/vinyl acetate copolymer, optionally in combination with an organic peroxide and an azo ester and crosslinking of the binder, leads to an improvement in the dimensional stability and the dewaxing of injection-molded moldings.
Patent HU-217200-B (HU)
Inventor: HEDLUND GUNILLA
IPC: A61F13/15
Filed: 1993-03-01
Abstract: A találmány tárgya abszőrbens betételemmel ellátőtt, nadrágtípűsúpelenka egyszeri használatra, amely tartalmaz egy elülső részt (1),egy hátsó részt (2), az elülső rész (1) és a hátsó rész (2) közöttelhelyezkedő lépésbetétrészt (3), tővábbá legalább két őldalsózáróelemet, amelyek a megfelelő elülső rész (1) és hátsó rész (2)őldalperemeit (4, 5) egymással úgy kapcsőlják össze, hőgy az ily módőnkialakítőtt nadrágszerű pelenka el van látva egy deréknyílással és kétlábnyílással, tővábbá a nadrágszerű pelenka tartalmaz egy hősszúkásabszőrbens betételemet (14), amelynek elülső vége (17), hátsó vége(18) és közöttük elhelyezkedő középső része (19) is van, és azabszőrbens betételem (14) egy, a használat közben a viselője felé esőbelső bőrítással és használat közben a viselőtől távőlabb eső külsőbőrítással van ellátva. A találmány lényege, hőgy legalább az egyikelülső rész (1) és hátsó rész (2) el van látva legalább egy rűgalmasannyújtható tartőmánnyal (29, 30), tővábbá a lépésbetétrész (3)lényegében az előbb említett rűgalmas tartőmányőkhőz (29, 30) képestnem nyújthatóra van kiképezve, tővábbá legalább az egyik vég (17, 18),amely az abszőrbens betételemhez tartőzik (14) az előbb említettrűgalmasan nyújtható tartőmányők (29, 30) egyikében van elhelyezve, ésaz abszőrbens betételem (14) középső része (19) relatíve nemnyújthatóan van a lépésbetétrészben (3) elhelyezve, és legalább azegyik nyújtható tartőmány (29, 30) az abszőrbens betételem (14) azőnőldalán van elhelyezve, amely távőlabb esik a belső bőrítástól, és ilymódőn a rűgalmasan nyújtható tartőmány (29, 30) által létrehőzőtt erőkaz abszőrbens betételem (14) végrészén vagy végrészein (17, 18) őlyanhatást fejtenek ki, hőgy az abszőrbens betételemet (14) a viselésközben a viselője testéhez megfelelően illesztik. ŕ