baber/WOPTO huggingface dataset:
Patent NZ-531855-A (NZ)
Title: Amide derivatives as glycogen synthase kinase 3-beta inhibitors
Inventor: FREYEN EDDY JEAN EDGARD
IPC: A61K31/5377
Filed: 2002-10-29
Abstract: A compound of formula I is described to be used in the manufacture of a medicament for the prevention or treatment of diseases mediated through GSK3. R1 is hydrogen; aryl; formyl; C1-6alkylcarbonyl; C1-6alkyl; C1-6alkyloxycarbonyl; C1-6alkyl substituted with formyl, C1-6alkylcarbonyl, C1-6alkyloxycarbonyl, C1-6alkylcarbonyloxy; C1-6alkyloxyC1-6alkylcarbonyl optionally substituted with C1-6 alkyloxycarbonyl; X is selected from the group consisting of -NR1-; -NH-NH-; -N=N-; -O-; -C(=S)-; -O-C(=O)-; -C(=O)-O-; -C(=O)-C1-6alkyl; -C(=O)-O-C1-6 alkyl; R2 is hydrogen, C1-10alkyl, C2-10alkenyl, C2-10alkynyl, R20, each of the groups representing R2 may optionally be substituted where possible; R3 is hydrogen; hydroxy; halo; C1-6alkyl optionally substituted; C2-6alkenyl optionally substituted; C2-6alkynyl optionally substituted; C1-6alkyloxy; C1-6alkylthio; C1-6alkyloxycarbonyl; C1-6alkylcarbonyloxy; carboxyl; cyano, nitro; amino; mono- or di(C1-6alkyl)amino; polyhaloC1-6alkyl; polyhaloC1-6alkyloxy; polyhaloC1-6alkylthio; R21; R21-C1-6alkyl; R21-O-; R21-S-; R21-C(=O)-; R21-S(=O)p-; R7-S(=O)p; R7-S(=O)p-NH-; R21-S(=O)p-NH-; R7-C(=O)-; -NHC(=O)H; -C(=O)NHNH2; R7-C(=O)-NH-; R21-C(=O)-NH-; -C(=NH)R7; -C(=NH)R21; R4a or R4b each independently are hydrogen, R8, -Y1-NR9-Y2-NR10R11, -Y1- NR9-Y1-R8, -Y1- NR9R10; and s is 1 or 2.
Patent NZ-533636-A (NZ)
Title: A food grade lantibiotic from streptococcus macedonicus and uses thereof
Inventor: DE VUYST LUC
IPC: A01N63/50
Filed: 2002-11-21
Abstract: Disclosed is a novel food grade bacteriocin, namely a lantibiotic, named macedocin and produced by Streptococcus macedonicus ACA-DC 198. Macedocin inhibits a broad spectrum of lactic acid bacteria as well as several food spoilage and pathogenic bacteria, among others Clostridium tyrobutyricum, and is heat stable and active in a broad pH range. Also disclosed is the use of non pathogenic microorganisms for producing macedocin in food fermentation processes, such as for preparing milk products, butter, cheese and fermented meat and vegetables, as well as in non-fermented food products such as raw meat, modified-atmosphere-packed meat products, ready-to-eat meals, and canned food products, and its use for the preparation of functional starter cultures and cocultures.
Patent NZ-536304-A (NZ)
Title: Method for modifying gum arabic
Inventor: HAYASHI HIDEO
IPC: A23L29/25
Filed: 2002-08-08
Abstract: A method of modifying gum arabic for improving its emulsifying power is disclosed, wherein particles obtained by roughly granulating gum arabic are heated to 40 DEG C or higher in an atmosphere having a relative humidity of 30 to 100% to thereby obtain a modified gum arabic having an excellent emulsifying power. In this method, particles of gum arabic are prevented, during a processing step, from arousing or suffering troubles such as adhesion to one another to form a candy-like mass, deposition on the vessel, drying, or scorching. This modified gum arabic is suitable for use as an emulsifying agent for drinks, confectionery, chewing gum, oil-based perfumes, oil-based colorants, oil-soluble vitamins, etc.
Patent NZ-537368-A (NZ)
Title: Bait for control of animal pests, comprising a vitamin D sterol and a calcium compound
Inventor: WEAVER ERIC RAYMOND
IPC: A01N45/00
Filed: 2004-12-23
Abstract: Disclosed is a bait for control of animal pests, containing an ingestible base material, and including 0.4% to 1.25% by mass of a vitamin D sterol, and calcium compound within the range 0.25% to 3.0% by mass, selected from a calcium phosphate or calcium sodium lactate, or mixtures of a calcium phosphate and a calcium sodium lactate, and wherein the calcium sodium lactate may be replaced directly with calcium potassium lactate. (61) Addition to 329006
Patent NZ-538638-A (NZ)
Title: Stable, low free formaldehyde, synergistic antimicrobial compositions of aldehyde donors and dehydroacetic acid
Inventor: LUTZ PATRICK JAY
IPC: A61K31/19
Filed: 2003-08-20
Abstract: Disclosed is an antimicrobial composition comprising a synergistic antimicrobial effective amount of a mixture of: (a) a first component including one or more aldehyde donor; (b) a second component including a stabilizer selected from the group consisting of hydantoins, their derivatives, and urea and its derivatives; and (c) a third component including dehydroacetic acid or a salt thereof.
Patent NZ-539819-A (NZ)
Title: Compositions and therapeutic methods involving isoflavones and analogues thereof
Inventor: HEATON ANDREW
IPC: A23L1/30
Filed: 2000-09-06
Abstract: Disclosed herein are substituted isoflavone compounds of formula (I), wherein the variables are as defined in the specification. These compounds are used in the manufacture of medicaments for the treatment of diseases mediated by the estrogen receptor.
Patent NZ-545838-A (NZ)
Title: Process for the preparation of N-amino substituted heterocyclic compounds
Inventor: WEIBERTH FRANZ
IPC: A61K31/405
Filed: 2004-10-01
Abstract: Disclosed is a process for the preparation of a compound of the formula II which consists essentially of the steps of: a) preparing a solution of hydroxylamine-O-sulfonic acid in a suitable organic solvent; b) preparing a solution of suitable base in a suitable organic solvent; c) preparing a solution of a compound of the formula I in a suitable organic solvent; d) contacting simultaneously and proportionally said solution from said step a) and said solution from said step b) with said solution from step c) taken in a suitable reaction vessel at a suitable reaction temperature to provide said compound of formula II) in high purity and high yields; wherein the substituents are disclosed within the specification.
Patent NZ-545974-A (NZ)
Title: Connecting fastener and fastener holder
Inventor: UEJIMA YASUTSUGU
IPC: B25B/
Filed: 2004-09-16
Abstract: A fastener set, including (a) multiple fasteners each having a head part and a shaft part, and (b) a fastener holder which retains the fasteners in a grouping in which the fasteners are positioned parallel to one another and with spacing at appropriate intervals for intermittent transfer of the fasteners for driving by a power operated driving tool one at a time, is disclosed. The fastener holder includes a pair of separate belt-shaped parts disposed so that the shaft part of each fastener extends through both belt-shaped parts. The belt-shaped parts are spaced in an axial direction along the fasteners and are in a mutually parallel configuration. Each of the belt-shaped parts includes multiple ring-shaped unit retaining parts that have an outer dimension which is greater than or equal to a width of the head parts an arranged for being supported on a guide body of the driving tool. Each ring-shaped unit retaining part has a fastener through hole formed therein. The fastener through holes are arranged at appropriate intervals whereby the shaft part of each of the fasteners extends through a respective fastener through hole of each of the belt-shaped parts. At least one of the belt-shaped parts has a plurality of separated and mutually spaced cylindrical gripping parts which communicate with the fastener through holes of the belt-shaped part, and which are arranged for gripping the shaft parts of the fasteners.
Patent NZ-548929-A (NZ)
Title: Improved modalities for the treatment of degenerative diseases of the retina
Inventor: KLIMANSKAYA IRINA V
IPC: A61K35/44
Filed: 2005-01-24
Abstract: Provided is a method for producing a purified population of retinal pigment epithelium (RPE) cells, the method comprising: (a) providing a multilayer population of pluripotent human embryonic (hES) cells, wherein said pluripotent hES cells are not blastomeres; (b) culturing said multilayer population of pluripotent hES cells under conditions that do not maintain the undifferentiated state of said pluripotent hES cells for a sufficient time for the appearance of putative RPE cells, wherein said putative RPE cells comprise brown pigment dispersed within their cytoplasm; (c) selecting one or more of said putative RPE cells from the culture of step (b); and (d) culturing said one or more of said putative RPE cells selected in step (c) to form a cell monolayer containing cells that are Pax6- and bestrophin+ and exhibit a characteristic cobblestone, polygonal, epithelial-like appearance and comprise brown pigment dispersed within their cytoplasm, wherein said pluripotent hES cells are not used to generate a human being. The cell can be used to treat Parkinson's disease.
Patent NZ-549538-A (NZ)
Title: Methods for coupling resistance alleles in tomato
Inventor: HOOGSTRATEN JACOBUS GERARDUS JOANNES
IPC: A01H5/08
Filed: 2005-02-11
Abstract: Disclosed is a Lycopersicon esculentum plant, or part thereof, having reduced drag associated with the introduction of alleles from a member of the Lycopersicon genus that is not from the species of esculentum comprising: a. at least two resistance alleles present in the coupling phase at different loci within its genome, wherein one of said at least two resistance alleles is not the Mi-J allele from L. chilense; and b. at least one wild type Lycopersicon esculentum allele at the Mi or Ty loci of a homologous chromosome. Also disclosed is a Lycopersicon esculentum plant, or part thereof, comprising within its genome at least one tomato yellow leaf curl virus (TYLCV) resistance allele and at least one root knot nematode resistance allele, characterized in that said resistance alleles are present in the coupling phase at different loci on one chromosome and in that said plant is resistant against TYLCV and in that said plant is highly resistant against at least one root knot nematode species selected from the group consisting of Meloidogyne arenaria, Meloidogyne incognita and Meloidogyne javanica and wherein said at least one root knot nematode resistance allele is not the Mi-J allele from L. chilense.
Patent NZ-549748-A (NZ)
Title: A toothbrush head having a flexible bristle carrier capable of resiliently bending under the forces of toothbrushing
Inventor: CLOS THOMAS
IPC: A46B3/20
Filed: 2005-03-07
Abstract: A toothbrush head, connected or connectable to a toothbrush grip handle to define a head-handle length direction, with a width direction perpendicular to the longitudinal direction, is disclosed. The toothbrush head comprises a flexible bristle carrier, on which bristles are mounted, a base part closest to the toothbrush handle when connected, a longitudinally opposite tip part, and a support which supports the carrier. The support supports the carrier at the base part and at the tip part, leaving the carrier unsupported in a region longitudinally between these parts. The carrier is flexible such that it can deform under the forces of toothbrushing so that both its longitudinal and widthways sections become distorted. The support is capable of resilient bending deformation so that under the forces encountered in toothbrushing the tip part of the carrier can move resiliently to follow an arc in a plane perpendicular to the width direction.
Patent NZ-550936-A (NZ)
Title: Carbonated beverage dispenser
Inventor: GRANT ROBERT P
IPC: B65D1/02
Filed: 2005-05-04
Abstract: A carbonated beverage dispenser is disclosed. The beverage dispenser includes an expanded rounded rear end (150), an offset spout (120), a substantially flat side (170) and a substantially curved side (180) positioned between the expanded rounded rear end and the offset spout.
Patent NZ-551063-A (NZ)
Title: Vehicle and method for harvesting espalier fruit, especially berries or grapes
Inventor: HAMATSCHEK JOCHEN
IPC: C12G1/12
Filed: 2005-06-15
Abstract: A vehicle 1 for harvesting espalier fruit (grapes, berries) or olives and for further processing the fruit on the harvesting vehicle includes a frame 2 reaching over a row of plants within a U-shaped recess of the frame, wheels 3 on the sides of the frame and the U-shaped recess, a picker device 18 for separating the fruits from the plants, and a screw centrifuge 4 arranged directly on the vehicle. The centrifuge is adapted for the separation and clarification of a fruit mash into at least a solids phase and a liquid phase, and is preferably a solid bowl screw centrifuge rotating within a protective cage on the vehicle frame.
Patent NZ-553809-A (NZ)
Title: Use of polypeptides obtained through systematic mutations of single amino acids of human and non-human box-A of HMGB1 to prevent and/or antagonize pathologies induced by HMGB1
Inventor: FUMERO SILVANO
IPC: A61K38/17
Filed: 2005-09-05
Abstract: Provided is a mutant polypeptide variant of the human high affinity binding domain Box-A with a specified amino acid sequence or a biologically active fragment thereof, wherein said polypeptide variant exhibits an increased resistance to the proteolytic activity of proteases compared to the wild type. The compositions are useful for treatment of pathological conditions mediated by activation of the inflammatory cytokine cascade.
Patent NZ-562768-A (NZ)
Title: Device for controlling the stroke of a plunger of an aluminium production electrolytic cell feeding system
Inventor: COUVREUR SEBASTIEN
IPC: C25C3/14
Filed: 2005-09-09
Abstract: Device for controlling the travel distance of a chisel (13) for a feeding system for an electrolytic cell designed for aluminium production is disclosed. , The cell comprises an electrolytic bath (4) covered with a crust (5). The chisel (13) is carried by a. rod (14) fixed to the rod of an actuator (15) controlling vertical displacement of the chisel between a high position in which it is above the crust (5) and a low position in which the crust (5) is perforated and in which contact is made with the bath (4). The device (11) comprises means of detecting electrical contact between the chisel (13) and the bath (4). These means comprises an electrical circuit (19) capable of making an electrical measurement between the chisel (13) and a point (20) in the cell used as an electrical reference, and taking immediate action on the actuator to cause vertical upwards displacement of the chisel when a predetermined value of an electrical measurement is reached. The electrical circuit (19) is connected to the chisel (13) or to the rod (14) of the chisel (13) through connecting means capable of creating a point contact (24) at least one point between the circuit (19) and the chisel (13) or the rod (14) of the chisel (13). These connecting means (23) are acted upon by elastic means (25) pushing them towards the chisel or the rod (14) of the chisel (13), respectively.
Patent NZ-567601-A (NZ)
Title: Orally absorbed pharmaceutical formulation and method of administration
Inventor: GLUSKIN ANNA E
IPC: A61K9/107
Filed: 2005-11-30
Abstract: Disclosed is a pharmaceutical formulation for absorption through oral mucosae comprising and effective amount of (a) a pharmaceutical agent in mixed micellar form, (b) at least one micelle-forming compound selected from the group comprising an alkali metal alkyl sulphate and a polyoxyethylene sorbitan monooleate, (c) a block copolymer of polyoxyethylene and polyoxypropylene, (d) at least one additional micelle-forming compound chosen from the group comprising trihydroxyoxocholanyl glycine and salts thereof, glycerin, polyglycerin, lecithin, hyaluronic acid, glycolic acid, lactic acid, chamomile extract, cucumber extract, oleic acid, linoleic acid, linolenic acid, monolein, monooleates, monolaurates, borage oil, evening primrose oil, menthol, polyglycerin, lysine, polylysine, triolein, polyoxyethylenen ethers, polidocanol alkyl ethers, chenodeoxycholate, deoxycholate, alkali metal salicylate, pharmaceutically acceptable edetate, and pharmaceutically acceptable salts, and (e) a suitable solvent.
Patent NZ-568164-A (NZ)
Title: Staphylococcus aureus strain CYL1892
Inventor: LEE CHIA Y
IPC: C07H5/04
Filed: 2006-11-21
Abstract: Disclosed is a strain of Staphylococcus aureus comprising a constitutive promoter wherein said constitutive promoter is operably linked to a cap5 operon.
Patent NZ-577683-A (NZ)
Title: Method and apparatus for generating toxicology reports
Inventor: BACKER RONALD
IPC: G06F19/00
Filed: 2007-12-03
Abstract: Disclosed is a computer-implemented method for generating a toxicology report comprising: receiving a toxicology sample; receiving patient data, the patient data including patient medication information; performing a lab test on the toxicology sample to produce a lab result, the lab result including data indicative of the presence of a drug in the toxicology sample; storing the lab result in association with the data indicative of the lab test; submitting the lab result to a rules engine to produce a rules engine output, the rules engine including a toxicology rule, the toxicology rule being associated with the drug and the patient medication information; and generating a supplemental explanation report based on the lab result and the rules engine output, the supplemental explanation report including a plain language sentence explaining the lab result.
Patent NZ-582708-A (NZ)
Title: Heterocyclic amide compounds as protein kinase inhibitors
Inventor: SIDDIQUI M
IPC: C07D413/14
Filed: 2008-07-17
Abstract: The disclosure relates to heterocyclic amide compounds of formula depicted herein and pharmaceutically acceptable salt thereof. Also disclosed are compositions comprising said compounds, and methods for using said compoundsfor treating or preventing a proliferative disease, an anti-proliferative disorder, inflammation, arthritis, a neurological or neurodegenerative disease, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease or a fungal disease.
Patent NZ-582771-A (NZ)
Title: An ankle protector with elastic webbing, a cushion, and a pair of disc shape shields
Inventor: SCHEFFER HARALD
IPC: A63B71/12
Filed: 2008-06-25
Abstract: An ankle protector (10) is disclosed. The ankle protector comprises elastic webbing element (11), formed with a tubular construction thereby to surround and embrace a user's ankle region, a cushioning element (17) is attached to the webbing element (11), and a pair of disc shaped shield elements (15). The webbing element (11) is defined by upper and lower apertures (12, 13) to enable a user's foot (21) to pass through when putting the ankle protector (10) on. Each of said upper and lower apertures (12, 13) is formed by overlock-stitching (22) an edge of the elastic webbing (11) material, such that said apertures (12, 13) have no perceptible ribs. The cushioning element (17) is attached to the webbing element (11) and is adapted to cover and protect a user's Achilles tendon. The cushioning element (17) protrudes inwardly relative to the circumference of the tubular webbing element (11). The pair of disc-shaped shield elements (15) are located within the webbing element and adapted to cover and protect a user's lateral and medial malleoli.
Patent NZ-585511-A (NZ)
Title: Electrical energy distriution system with a supply side and delivery side form a DC loop
Inventor: HARRISON CRAIG WILLIAM
IPC: H02J3/36
Filed: 2008-10-17
Abstract: Disclosed is an electrical energy supply and distribution system suitable for medium scale Supply. The system includes a supply side for supply of electrical energy with plural connection ports for selective connection to respective electrical energy generators. Each connection port includes a bypass to allow direct current to flow through the port in the absence of a generator connected at that port, and electricity conditioning circuitry to deliver and vary direct current power supply to the loop from a connected generator. The system also includes a delivery side for delivery of electrical energy with plural connection ports for selective connection to respective electrical energy loads. Each connection port includes a bypass to allow direct current to flow through the port in the absence of a load connected at that port, and electricity conditioning circuitry to deliver and vary electrical power supply to a load connected at the port. When observed from the electrical energy generators and the electrical energy loads, the supply side and delivery side are connected end to end to form a direct current loop.
Patent NZ-588344-A (NZ)
Title: Separation disc and milk separator where the seperation disc is shaped as a truncated cone with a flange across the narrowest part of the cone
Inventor: LINDROTH PER-OLOF
IPC: B04B1/08
Filed: 2009-04-07
Abstract: 588344 A separation disc 3 for a milk separator comprising a rotor 1, which separation disc together with other separation discs 3 forms a stack of separation discs 3 which are rotatable together with the rotor 1 about an axis of rotation x. The separation disc 3 comprises a truncated substantially conical portion 3a and an annular flange element 3b which is connected to the conical portion 3a at the latter's smallest radius and extends therefrom radially inwards substantially perpendicular to the axis of rotation x, which flange element 3b has a radial extent corresponding to at least 10% of the radial extent of the substantially conical portion 3a. The inner radial edge of the flange element 3b is provided with a number of recesses 3d distributed along the circumference of the edge and adapted to protrusions 4a on a column 4 which is connected to the rotor 1 and which extends coaxially through the stack of separation discs 3. The recesses 3d are so configured that the protrusions 4a fill substantially the whole of the recesses 3d and the radial extent of the recesses 3d corresponds to at least 20% of the radial extent of the flange element 3b, the column protrusions 4a being adapted to entraining the cream during operation of the milk separator.
Patent NZ-590402-A (NZ)
Title: Refractory coating for a wind turbine component of thickness 10nm to 1000um
Inventor: HOHLE ANDREAS CHRISTIAN
IPC: F03D11/00
Filed: 2011-01-10
Abstract: A wind turbine (1) is disclosed which comprises at least one component (10) having a surface (12). The surface (12) is coated at least in part with a refractory layer (13), preferably a boron-based refractory layer. The thickness of the layer is 10 nm to 1000um.
Patent NZ-595574-A (NZ)
Title: Anti-fcrh5 antibodies and immunoconjugates and methods of use
Inventor: HONGO JO-ANNE
IPC: A61K33/243
Filed: 2010-03-31
Abstract: NZ 595574 Disclosed is an isolated monoclonal anti-FcRH5 antibody, as defined in the complete specification. Also disclosed are immunoconjugates comprising the specific anti-FcRH5 antibody covalently attached to a cytotoxic agent. The disclosed anti-FcRH5 antibody and immunoconjugates are used in the treatment of cancer.