baber/WOPTO huggingface dataset:
Patent JP-2014054633-A (JP)
Title: Device and method for separating magnetic particle
Inventor: LUIS MIQUEL MARTINEZ GARCIA
IPC: H01F7/02
Filed: 2013-11-05
Abstract: PROBLEM TO BE SOLVED: To provide a separator of a magnetic particle capable of generating a magnetic field of various dimensions, by using several predetermined magnetic elements or magnets.SOLUTION: A nonuniform magnetic field generator having an internal space 1 for receiving an object for separating a magnetic particle is a device that has a support structure for the magnets and a plurality of magnets 3 positioned in the support structure, the magnets 3 having a polygonal shape having a plurality of side parts; and forms at least one ring 4 formed of the magnets 3 around the internal space 1 for generating a magnetic field in the internal space 1 such that the number of magnetic poles P becomes an even number larger than 2, the respective magnets 3 having a predetermined magnetization direction 5 in a cross section of a generator and the magnetization direction 5 of the magnets 3 being positioned so as to follow an angular advance of Δy=((P/2)+1)×Δθ (in the cross section of the generator, Δy expresses a variation in the magnetization direction 5 between one magnet 3 and the next magnet 3, Δθ expresses a variation in an angular position between the one magnet 3 and the next magnet 3, and the ring 4 includes the magnets 3 more than the number of magnetic poles P).
Patent JP-2015094589-A (JP)
Title: Visual inspection device
Inventor: NAKAGAWA HIROMITSU
IPC: H05K13/08
Filed: 2013-11-08
Abstract: PROBLEM TO BE SOLVED: To provide a visual inspection device configured to allow conditions and thresholds to be set on the basis of non-defective data without defective data, to prevent a defective from being missed at the start of a model, while allowing quality determination inspection conditions, a quality determination threshold, and a process failure threshold to be set optimally.SOLUTION: A visual inspection device includes: an imaging unit 5 which images an appearance of a printed board; an image input unit 12 which inputs a signal obtained from the imaging unit 5; an image processing unit 15 which processes an input image; a measurement unit which calculates feature quantities by using the processed image; and a control unit 7 which controls the device. The visual inspection device which performs determination on preset thresholds includes: a condition determination unit 20 which determines whether a printed board is a defective or not, by use of a first threshold; and a condition determination unit 20 which determines a process failure by use of a second threshold, after the quality determination based on the first threshold.
Patent JP-2015094079-A (JP)
Title: Structural body
Inventor: MACHINAGA TAKAHIRO
IPC: E04H12/10
Filed: 2013-11-08
Abstract: PROBLEM TO BE SOLVED: To provide a structural form that reduces the bending deformation amount of a core portion at the time of an earthquake.SOLUTION: A structural body 10 includes: a core portion 20; a plurality of outer peripheral columns 30 surrounding the core portion 20; a plurality of upper beam materials 42A and a plurality of lower beam materials 42B which respectively protrude from the core portion 20, are installed on each of the plurality of outer peripheral columns 30 to structure a frame with the core portion 20 and the outer peripheral columns 30; and a diagonal member 44 provided in the frame. Among the adjacent outer peripheral columns 30, the upper beam materials 42A and lower beam materials 42B installed on one of the outer peripheral columns 30 have different protruding heights HHprotruding from the core portion 20 from the upper beam materials 42A and lower beam materials 42B installed on the other outer peripheral column 30.
Patent JP-2015095037-A (JP)
Title: Movement information processing method, movement information processing program, and movement information processor
Inventor: KASAMA KOICHIRO
IPC: G08G1/005
Filed: 2013-11-11
Abstract: PROBLEM TO BE SOLVED: To calculate the distance of a return path through which a user is highly likely to pass until returning to reception.SOLUTION: A movement locus information acquisition unit 30 is configured to acquire the information of the movement locus of the forward path of a user from a departure spot to a current spot, and to store the information in a movement locus line management table 40. A movement locus processing unit 32 is configured to, when the user passes through a certain position at a certain time, and then passes in a predetermined range including the position at another time, specify a movement locus between both time as a redundant locus by referring to the acquired information of the movement locus of the forward path. An information transmission unit 34 is configured to specify the return path by deleting the redundant locus from the information of the movement locus of the forward path, and to calculate the distance of the return path.
Patent JP-2014050406-A (JP)
Title: Improved carbon capture in fermentation
Inventor: OAKLEY SIMON DAVID
IPC: C12P7/54
Filed: 2013-11-12
Abstract: PROBLEM TO BE SOLVED: To provide a system and method to increase overall carbon capture and/or overall efficiency in a process including microbial fermentation of a syngas substrate, particularly including CO.SOLUTION: The method in one embodiment comprise the steps of; gasificating feedstock in gasifier 1 to produce syngas stream containing CO, CO2 and H2; and producing exit stream containing at least one product, and CO2, methane, H2 and CO, by contacting at least a portion of the syngas stream with at least one microorganism in fermentation condition in bioreactor 7. The method in another embodiment comprises the step of ; separating at least a portion of the exit gas thereby providing a first stream containing CO2 and methane and a second stream containing H2 and CO; and directing the first stream to the gasifier to produce syngas. Overall carbon capture efficiency in gasification/fermentation process which produces product such as alcohol is improved by the invention.
Patent JP-2015101592-A (JP)
Title: Polyurethane resin and molded article thereof
Inventor: INUI SHINYA
IPC: C08G18/66
Filed: 2013-11-21
Abstract: PROBLEM TO BE SOLVED: To provide a urethane resin which can reduce environmental load from the viewpoint of carbon neutral and achieve physical properties equivalent to those of a usually used urethane resin even if a raw material derived from plants is used.SOLUTION: There are provided: a polyurethane resin which comprises a biogenic polyol having a number average molecular weight of 200 to 1200, which is at least one selected from the group consisting of an alkylene oxide adduct of glycerin derived from plants, an alkylene oxide adduct of sucrose and an alkylene oxide adduct of sorbitol, castor oil or a caster oil derivative and cellulose, and is obtained by reacting a polyol component in which the ratio of the biogenic component in the total weight is 50 to 95 wt.% and a polyisocyanate component containing a biogenic carbonate; and a polyurethane resin molded article obtained by molding the polyurethane resin.
Patent JP-2015100410-A (JP)
Title: Brain function measurement instrument and brain function measurement method
Inventor: YAMADA TORU
IPC: G01N21/17
Filed: 2013-11-21
Abstract: PROBLEM TO BE SOLVED: To provide a brain function measurement instrument and a brain function measurement method which implement efficient brain function measurement with fewer detection means such as probes to reduce burden on a subject.SOLUTION: A brain function measurement instrument 1 comprises: a detection unit 3 including a plurality of probes which have a selectively operable light projection part and light detection part formed integrally and which are regularly arranged in a subject's head; a control unit 10 for selectively operating the light projection part and the light detection part in each of the probes such that the light detection part only detects the light projected by the light projection part in one of the adjacent probes at any time point; and a data measurement unit 11 for measuring the intensity of the light detected by the light detection part. A brain function measurement method using the brain function measurement instrument 1 or the like is also provided.
Patent JP-2015101757-A (JP)
Title: Film deposition method
Inventor: YOSHIDA MAKOTO
IPC: C23C14/04
Filed: 2013-11-25
Abstract: PROBLEM TO BE SOLVED: To provide a film deposition method capable of forming a film having high reliability by high quality by suppressing a heat influence from a heat source upon evaporation or upon sputtering even to a film deposition object member having a three-dimensional structure in film deposition processing.SOLUTION: When applying film deposition processing to a film deposition object member 1 comprising a resin material by an evaporation method or a sputtering method under a vacuum environment, a first mask 10 is arranged adherently to the film deposition object member 1 to which the film deposition processing is applied, and a second mask 20 having excellent heat reflectivity is arranged at a prescribed fixed interval from the first mask 10 so as to cover the first mask 10.
Patent JP-2014196585-A (JP)
Title: Filament nonwoven fabric and laminated fabric comprising the filament nonwoven fabric
Inventor: KANAYAMA YOTARO
IPC: D06C29/00
Filed: 2013-12-02
Abstract: PROBLEM TO BE SOLVED: To provide a filament nonwoven fabric that has irregular uneven creases (or crepes) with extreme differences in height (bulkiness) formed thereon and has a light weight and a sufficient strength, and to provide a laminated fabric comprising the filament nonwoven fabric.SOLUTION: A filament nonwoven fabric comprises filaments and has irregular uneven creases having extreme differences in height formed thereon. A laminated fabric comprises the filament nonwoven fabric (an inner layer) and a first fabric (a first outer layer) laid on one side of the filament nonwoven fabric. A first space part is formed between the filament nonwoven fabric (the inner layer) and the first fabric (the first outer layer).
Patent JP-2015105067-A (JP)
Title: Automobile visor, and fitting structure of automobile visor
Inventor: KAWAHASHI NORIO
IPC: F16B21/04
Filed: 2013-12-02
Abstract: PROBLEM TO BE SOLVED: To provide an automobile visor and a fitting structure of the automobile visor which prevent deformation and breakage of a projection body and do not generate shrinkage on the outer surface of the visor as a result.SOLUTION: In an automobile visor 1 and a fitting structure of the automobile visor 1, because a projection body 5 projecting from an eaves body 4 is inserted into a reinforcement member 6 and one end of a fitting bracket 10 is fitted to the reinforcement member 6 by inserting the reinforcement member 6 into the one end, even if a large load is applied to the projection body 5, it is possible to prevent deformation and breakage of the projection body 5 by dispersing the load to the reinforcement member 6 and the fitting bracket 10. Also, since it is not necessary to provide a rib to the projection body 5, shrinkage is not generated on an outer surface of the eaves body 4.
Patent JP-2015108950-A (JP)
Title: Printing system, information processing apparatus, program, and image forming apparatus
Inventor: IWASAKI MANABU
IPC: B41J29/38
Filed: 2013-12-04
Abstract: PROBLEM TO BE SOLVED: To supply print data to be printed from a print service system to an image forming apparatus that is not registered in advance by a user in the print service system to be used by the user.SOLUTION: An image forming apparatus 100 is registered in advance in a cloud print service 200 and provided with a physical printer ID. When a user brings a portable terminal 500 close to the image forming apparatus 100, the physical printer ID is notified from the image forming apparatus 100 to the portable terminal 500 by proximity wireless communication. The portable terminal 500 transmits a setting request including the physical printer ID and a user ID of the user to the cloud print service 200. In response to the setting request, the cloud print service 200 creates setting information enabling the user to temporarily use the image forming apparatus 100 and stores the information.
Patent JP-2014040842-A (JP)
Title: Valve gear of internal combustion engine
Inventor: WAKABAYASHI TOMOHIRO
IPC: F01L1/356
Filed: 2013-12-05
Abstract: PROBLEM TO BE SOLVED: To improve operation responsiveness of a variable valve timing mechanism.SOLUTION: A valve gear includes a camshaft, a hydraulic variable valve timing mechanism, a hydraulic control valve, and a control oil passage. The control oil passage is made of a first oil passage and a second oil passage. The first oil passage has a first journal oil passage and a first body-side oil passage, and the second oil passage has a second journal oil passage and a second body-side oil passage. The first body-side oil passage has a first connection oil passage linearly extending from the hydraulic control valve to a parting plane side, and the second body-side oil passage has a second connection oil passage linearly extending from the hydraulic control valve to the parting plane side and parallel to the first connection oil passage. The first journal oil passage and the second journal oil passage are located in parallel spaced apart from each other in a direction along a center axis of rotation of the camshaft. A valve axial line of the hydraulic control valve is substantially positioned on a specific cam orthogonal plane. An opening on the side opposite to the hydraulic control valve of the first connection oil passage and an opening on the side opposite to the hydraulic control valve of the second connection oil passage are arranged on the specific cam orthogonal plane.
Patent JP-2015112739-A (JP)
Title: Foam molding die
Inventor: MORI YASUHIRO
IPC: B29C45/26
Filed: 2013-12-09
Abstract: PROBLEM TO BE SOLVED: To reduce ununiformity of the size and distribution of an air bubble.SOLUTION: A foam molding die 10 for growing bubbles 27L and 27S to mold a foamable moltem resin 25 injected from a gate 16 while running the foamable moltem resin in a cavity 14 includes an evacuation space 18 having a form communicated with the cavity 14 at a position of a downstream end (a confluent point 19) in the flow path of the molten resin 25 or the vicinity thereof and storing a portion (a flow direction head part 25H) of the downstream end side in a flow direction in the molten resin 25.
Patent JP-2014209711-A (JP)
Title: Image processing apparatus, image processing method, and program capable of copying document
Inventor: ITO JUN
IPC: H04N1/00
Filed: 2013-12-17
Abstract: PROBLEM TO BE SOLVED: To enable chase control even in copying utilizing ACS (auto color select) determination processing.SOLUTION: An image processing apparatus comprises: storage means that stores an image read from a scanner; and control means that when the size of stored image data exceeds a predetermined size and a determination result of an ACS determination processing unit is obtained, performs control for starting output of image data even when image data corresponding to the whole reading target area is not stored in the storage means.
Patent JP-2015119006-A (JP)
Title: Semiconductor device manufacturing method
Inventor: HANAMAKI YOSHIHIKO
IPC: H01L21/28
Filed: 2013-12-17
Abstract: PROBLEM TO BE SOLVED: To provide a semiconductor device manufacturing method which improves in-plane uniformity of a contact resistance value between a semiconductor element and an ohmic electrode.SOLUTION: A semiconductor device manufacturing method comprises: a temperature maintenance process of maintaining a temperature within a range of a first temperature range for 30 seconds to 150 seconds in a temperature rising period before an annealing process of forming an ohmic electrode by annealing a multilayer metal layer. The first temperature range is a temperature within a range from a temperature lower the lowest melting point which s the lowest melting point among melting points of respective layers of the multilayer metal layer by 100°C to the lowest melting point. Temperature rising for proceeding to the annealing process after the temperature maintenance process is performed at a rate of temperature rise from 5°C/sec to 20°C/sec so as not to impair in-plane temperature uniformity of a wafer formed in the temperature maintenance process.
Patent JP-2015116281-A (JP)
Title: Ultrasonic diagnostic device
Inventor: UNAYAMA KENICHI
IPC: A61B8/00
Filed: 2013-12-18
Abstract: PROBLEM TO BE SOLVED: To provide an ultrasonic diagnostic device which can easily detect electric connection with an ultrasonic probe.SOLUTION: An ultrasonic diagnostic device includes a connector 4 and a detection part 5. The connector is so configured that a plurality of connection terminals which can be electrically connected with an ultrasonic probe are arranged, and a plurality of prescribed detection terminals are provided in a peripheral edge part in the arrangement. The detection part detects that the ultrasonic probe is connected when the prescribed detection terminals are connected.
Patent JP-2014121733-A (JP)
Title: Method for welding components including base layer together using condensed laser beam
Inventor: MAATTANEN ANTTI
IPC: B23K26/30
Filed: 2013-12-24
Abstract: PROBLEM TO BE SOLVED: To provide a method of welding components with a common surface region being three-dimensional.SOLUTION: A method of welding components including a base layer together by condensing laser beams on a common surface to the components. Energy of a focus 12 melts matters in two components 5 and 13 simultaneously, condensed laser beam 10 is provided so as to move relatively to the immovable components at a velocity of forming an integrated welded seam 15 when the molten matters are hardened. The invention is characterized in that if a coupled surface is three-dimensional, a height position of the focus 12 of the laser beam 10 can be changed depending on a measurement result of rays 7a and 7b traveling in front of the laser beam condensed on the common surface with certain accuracy.
Patent JP-2015123105-A (JP)
Title: Dishwasher
Inventor: MORIMURA MASARU
IPC: A47L15/42
Filed: 2013-12-25
Abstract: PROBLEM TO BE SOLVED: To provide a dishwasher with a simple structure capable of extruding a washing tank from a washer body appropriately and reducing discomfort of a user attributed to a motor operation sound.SOLUTION: A dishwasher 100 includes: a washer body 1 with an opening; a washing tank 2 accommodated in the washer body 1; a slide device 30 which includes a slide shaft 33 and a drive part 36 for driving the slide shaft 33 so as to extrude or draw back the slide shaft 33 for extruding the slide shaft 33 to extrude the washing tank 2 from the washer body 1; and a control part 40 for performing a control to draw back the slide shaft 33 at a velocity equal to or lower than the velocity at which the slide shaft 33 is extruded.
Patent JP-2015128007-A (JP)
Title: Sunlight daylighting system and exhibition system
Inventor: TANIGUCHI YUKIO
IPC: F21V5/02
Filed: 2013-12-27
Abstract: PROBLEM TO BE SOLVED: To provide a sunlight daylighting system which can illuminate a direction inclined to the vertical direction more brightly than the vertical direction.SOLUTION: A sunlight daylighting system 1 is configured to introduce and guide sunlight to a predetermined space, such as a room 92. The sunlight daylighting system 1 includes light path adjust means 30 which adjusts a light path for introduced sunlight. The light path adjust means 30 adjusts the light path for introduced sunlight so that outgoing light L from the sunlight daylighting system 1 to the room 92 has the peak of light intensity in a direction inclined to the vertical direction.
Patent JP-2013523490-A (JP)
Title: 多層フッ素化フィルム
IPC: B32B27/30
Filed: 2011-03-29
Abstract: 本発明は、フルオロポリマーより成る多層フィルムであって、農業分野で、とりわけ温室被覆フィルムとしての使用に適切となる特性を有する多層フィルムに関する。第１の態様により、本発明は、結晶化温度ＴｃＡを持つ第１のビニリデンフルオリドコポリマーで作られた層Ａ、および結晶化温度ＴｃＢを持つ第２のビニリデンフルオリドコポリマーで作られた層Ｂを含み、ＴｃＡがＴｃＢより大きく、層ＡおよびＢが交互に重なり、層Ａが外側に位置して、層Ｂが２つの層Ａの間に位置する、少なくとも３つの層を備える、多層フッ素化フィルムに関する。本発明の別の主題は、本発明によるフィルムの農業用被覆材料として、とりわけ温室被覆材としての使用に関する。
Patent JP-2013523761-A (JP)
Title: 多環式テトラサイクリン化合物
IPC: C07D487/04
Filed: 2011-03-30
Abstract: 本発明は、構造式（Ｉ）： 【化１】     によって表される化合物またはその薬学的に許容できる塩に関する。構造式（Ｉ）の変数は本明細書において規定される。構造式（Ｉ）の化合物を含む医薬組成物およびその治療的使用も記載される。
Patent JP-2013523807-A (JP)
Title: Ｐｉ３ｋにより誘発される癌のためのバイオマーカー
IPC: A61K39/395
Filed: 2011-04-01
Abstract: ｍＴＯＲＣ２複合体がターンモチーフスレオニンでのＰＫＮ３のリン酸化の調節において役割を有するという発見、およびバイオマーカーとしての、ＰＫＮ３のターンモチーフスレオニンのリン酸化状態の使用が開示される。いくつかの実施形態において、ＰＫＮ３のターンモチーフスレオニンのリン酸化状態は、抗リン酸化Ｔ８６０抗体などの、ＰＫＮ３タンパク質のターンモチーフスレオニンに特異的に結合する抗体を用いて決定される。いくつかの実施形態において、本発明は、癌治療の可能性を有する化合物をスクリーニングするための方法、癌を診断するための方法、癌に罹患している患者の予後を決定するための方法、臨床試験において患者を層別化するための方法、癌に罹患１０している患者を治療するための方法、および特定の治療レジメンの有効性を決定するための方法に関する。
Patent JP-2013524133-A (JP)
Title: 結合装置
IPC: F16D23/04
Filed: 2011-04-08
Abstract: 本発明は自動車のドライブトレインの結合装置に関し、本結合装置は、回転シャフト（２３）をドライブトレインの駆動要素（２５）に選択的に結合するために、回転シャフト上に配置された少なくとも１つのクラッチ（１１）を備えており、回転シャフトを駆動要素と結合するために、回転シャフトの軸に沿って第１のクラッチ部（２０）および第２のクラッチ部（２１）のうちの一方を移動させることによって、第１のクラッチ部および第２のクラッチ部が互いに嵌合係合できる。ドライブトレインにおけるジャークおよび振動を防止するために、液圧ダンピングデバイ（６５）が、第１のクラッチ部（２０）と第２のクラッチ部（２１）の間で作用する。
Patent JP-2013526147-A (JP)
Title: ゲートウェイの自動ダイヤル装置のサポート
IPC: H04M3/00
Filed: 2011-04-12
Abstract: 方法は、自動電話番号ダイヤル装置がゲートウェイにおいて同時に使用されているときに、ワイヤレスデジタルテレフォニーと従来のアナログテレフォニーの対立を解消するように機能する。この方法は、単一のアナログ電話回線が、ワイヤレスデジタル電話インターフェースを用いて動作もするシステム内の自動電話ダイヤル装置およびアナログ電話セットとインターフェースするとき、１つの電話回線を使用して動作する電話呼を優先するように作用する。この方法は、アクティブな呼が存在するかどうかを検出するステップと、ダイヤルされた電話番号がアクティブな呼よりも優先順位が高いかどうかを判定するステップとを含む。システム内の呼の発信元にかかわらず、最も高い優先順位に従って、最も優先順位が高い呼がかけられるまたは保存される。
Patent JP-2013526189-A (JP)
Title: フェムト支援アクティブハンドインを可能にするためにターゲットフェムトセルを一意に識別すること
IPC: H04W36/04
Filed: 2011-04-22
Abstract: モバイルアクセス端末のためのアクティブマクロ通信のマクロセルフェムトセル間ハンドインをサポートするためのシステム、方法、デバイス、およびコンピュータプログラム製品について説明する。帯域外（ＯＯＢ）リンクを使用して、（たとえば、フェムトセルと統合された、またはフェムトセルとの共通のサブネット中のＯＯＢ無線を使用して）アクセス端末がフェムトセルの近傍にあることを検出する。フェムトセルの近傍にあるアクセス端末を検出すると、アクセス端末をフェムトコンバージェンスシステムに効果的に事前登録するために、マクロネットワークと通信しているコアネットワーク中に配設されたフェムトコンバージェンスシステムにＯＯＢ存在指示を通信する。フェムトコンバージェンスシステムが、事前登録されたアクセス端末を示唆するハンドオフ要求をマクロネットワークから受信したとき、さもなければ適切なターゲットフェムトセルの識別情報が信頼できないであろう場合でも、フェムトコンバージェンスシステムは、事前登録に従ってハンドインのために使用すべき適切なターゲットフェムトセルを確実に判断することが可能である。
Patent JP-2013526801-A (JP)
Title: 撮像装置アレイおよびアレイカメラのためのアーキテクチャ
IPC: H04N5/345
Filed: 2011-05-12
Abstract: 本発明の実施形態によるアレイカメラで使用するために構成される、撮像装置アレイのアーキテクチャを説明する。本発明の一実施形態は、複数の焦点面であって、各焦点面は、各次元に少なくとも２つのピクセルを有するピクセルの２次元配設を備え、各焦点面は、別の焦点面からのピクセルを含有しない撮像装置アレイの領域内に含有される複数の焦点面と、焦点面内のピクセルによる画像情報の捕捉を制御するように構成される制御回路であって、制御回路は、焦点面のうちの少なくとも２つの中のピクセルによる画像情報の捕捉が別々に制御可能であるように構成される制御回路と、ピクセル出力をデジタルピクセルデータに変換するように構成されるサンプリング回路とを含む。
Patent JP-2013533336-A (JP)
Title: 炭酸カルシウム含有材料の水性懸濁液中の添加剤としての２−アミノエタノールの使用
IPC: C09D7/12
Filed: 2011-05-31
Abstract: 水性懸濁液の伝導率に関して改善された安定性を提供する、少なくとも１種の炭酸カルシウム含有材料を２５から６２体積％含有するその懸濁液中の添加剤としての２−アミノエタノールの使用。
Patent JP-2013531752-A (JP)
Title: 水中の油及びガス収集システム
IPC: E02B15/10
Filed: 2011-07-07
Abstract: 動作中、バルーン状の構造の下側にある開口を有する外皮によって定められるバルーン状の構造を含み、水中の供給源から油及びガスの収集するための装置であって、バルーン状の構造は：外皮のガスを排気するのに適合する孔、及び、孔により外皮のガスの流れを制御するのに適合する閉止弁を有する上位の油を制御するための制御手段を含み、弁は外皮のガスの最小容積を決定するために油に浮遊するように適合することができるフロートによって操作可能である閉止部材による閉止可能であり、使用中、バルーン状の構造は、前記水中の供給源から油及びガスを集めるため、供給源上に配置されるのに適合する。バルーン状の構造は、制御された方法で水面に上昇するのを可能にするため、構造の浮力を制御するのに適合した浮力手段をさらに含む。外皮は、貯蔵及び／又は輸送のために、畳む又は折り重なることができるように可撓性の材料で形成されてもよい。 【選択図】図１
Patent JP-2013538790-A (JP)
Title: Ｃｌｌ血液サンプルにおけるｃｄ３７抗体の優れた効果
IPC: A61P35/00
Filed: 2011-07-15
Abstract: 本発明は、ＣＬＬを有する患者、特に「ハイリスク」又は「超ハイリスク」グループの患者に属する患者の処置のためのＣＤ３７抗体、特にＡ２及びＢ２を説明する。それらの患者は、フルダラビン処置に抵抗性の患者、又は、予後不良若しくは処置失敗のリスクの増加を示す遺伝子マーカーを保有する患者（例えば、ＴＰ５３機能障害若しくは染色体１７ｐ１３の欠失を有する患者、又は、抗ＣＤ２０処置が過去に失敗した患者）のいずれかである。ＣＬＬ細胞を枯渇するＡ２及びＢ２の能力は、通常のリスクを有する患者、及び、リスクの増加を有する患者（「ハイリスク」患者）に由来する患者サンプルの両方において高く、リツキシマブ及びアレムツズマブのものよりも明らかに優れている。