baber/WOPTO huggingface dataset:
Patent CA-2644555-A1 (CA)
Inventor: VAN DE CASTEELE RUSSELL
IPC: A61K31/70
Filed: 2007-03-06
Abstract: A method of manufacturing a stable nanosuspension for delivery of a biologically active agent, particularly vitamin B-12, into the bloodstream of a subject is disclosed. A Nanofluidizable mixture containing vitamin B-12 is initially formed and processed via a nanofluidization process to form the stable nanosuspension, which may be administered via the transmucosal membranes or other suitable routes of administration. This product demonstrates increased bioavailability, enhanced period of onset, and enhanced stability for a controlled-release product.
Patent CA-2644644-A1 (CA)
Title: Method of mounting a circuit board
Inventor: NACHMANI AVIHU
IPC: H05K7/14
Filed: 2006-03-01
Abstract: A circuit board is mountable inside a case that houses a user interface device, such that the circuit board is proximate to a portion of an external wall of the case. The portion is situated such that when the case is oriented for the user interface device to be in communication with a user, the portion is conveniently between the circuit board and a location outside and relative to the case that is occupyable by an external device operable to communicate with the circuit board.
Patent CA-2644908-A1 (CA)
Title: System and method for restoring water supply pipes in buildings
Inventor: LEBEN MARC
IPC: B24C3/32
Filed: 2008-11-26
Abstract: A system and method for restoring water supply pipes in buildings is provided.    Compressed air is blown through one end of a cold water supply pipe, such as a cold water riser, and elsewhere on the pipe the cold water supply pipe is connected to the hot water supply pipe by an air hose. Compressed air may alternatively be blown through one end of the hot water supply pipe. To clean the pipe, abrasive particles are introduced into the stream of compressed air upstream of the section of pipe to be cleaned. To line the pipe, an epoxy coating is introduced into the stream of compressed gas upstream of the section of pipe to be lined.
Patent CA-2645214-A1 (CA)
Title: Methods for the identification of lrrk2 interacting molecules and for the purification of lrrk2
Inventor: DREWES GERARD
IPC: G01N33/68
Filed: 2007-03-13
Abstract: The invention provides in a first aspect a method for the identification of an LRRK2 interacting compound, comprising the steps of providing a protein preparation containing LRRK2, contacting the protein preparation with indol ligand 91 immobilized on a solid support under conditions allowing the formation of an indol ligand 91-LRRK2 complex, incubating the indol ligand 91-LRRK2 complex with a given compound, and determining whether the compound is able to separate LRRK2 from the immobilized indol ligand 91. Furthermore, the invention relates to a method for the identification of an LRRK2 interacting compound, comprising the steps of providing a protein preparation containing LRRK2, contacting the protein preparation with indol ligand 91 immobilized on a solid support and with a given compound under conditions allowing the formation of an indol ligand 91-LRRK2 complex, and detecting the indol ligand 91-LRRK2 complex. Additionally, the invention provides a method for the identification of an LRRK2 interacting compound, comprising the steps of providing two aliquots of a protein preparation containing LRRK2, contacting one aliquot with indol ligand 91 immobilized on a solid support under conditions allowing the formation of an indol ligand 91-LRRK2 complex, contacting the other aliquot with indol ligand 91 immobilized on a solid support and with a given compound under conditions allowing the formation of an indol ligand 91- LRRK2 complex, and determining the amount of indol ligand 91-LRRK2 complex. Furthermore, the invention relates to a method for the purification of LRRK2, comprising the steps of providing a protein preparation containing LRRK2, contacting the protein preparation with indol ligand 91 immobilized on a solid support under conditions allowing the formation of an indol ligand 91-LRRK2 complex, and separating LRRK2 from the immobilized indol ligand 91.
Patent CA-2645442-A1 (CA)
Title: Liquid-cooled grill/grate with wear plates
Inventor: STIEFEL THOMAS
IPC: F23H3/02
Filed: 2007-03-16
Abstract: The invention relates to a grill consisting of liquid-cooled grill plates and liquid-cooled lateral panels, the surfaces of which are provided with wear plates (1) connected to the liquid-cooled grill plates (2) and lateral planks in a heat-conducting manner. Said wear plates (1) consist of a wear-resistant material which must however by cooled. Advantageously, a layer of a heat-conducting material in the form of a highly heat-conducting soft silicon film (3) is clamped between the liquid-cooled grill plates (2) and lateral panels and the wear plates (1), said layer providing a good heat transfer between the wear plates (1) and the permeable grill plates (2) and central panels. It is thus ensured that, during operation, the wear plates (1) always remain in a non-critical temperature range as they are cooled by the underlying grill plates (2) and lateral panels which are cooled to ca. 50°C g.
Patent CA-2645952-A1 (CA)
Title: Reinforced glitter
Inventor: ARGOITIA ALBERTO
IPC: C09D7/65
Filed: 2008-12-05
Abstract: The invention relates to reinforced opaque glitter particles having substantially uniform shape and size. Each of the particles consists of a reflective core supported by a transparent organic substrate and one or more robustness-improving layers for providing rigidity to the particle. Optionally, the particles have lacquer layers at a surface of the particle.  One example of a robustness-improving layer is an inorganic transparent protective layer having a thickness of at least 20 nm adjacent directly to the aluminum layer. Another example is an adhesion promoting layer directly adjacent to the transparent organic substrate.
Patent CA-2646849-A1 (CA)
Title: Inhibiting formation face failure in oil and gas wells
Inventor: NORRIS MARK
IPC: E21B43/01
Filed: 2008-12-16
Abstract: A technique includes running a string into a well bore and inhibiting formation face failure. The well bore extends at least partially through a non-producing layer and a hydrocarbon formation layer. The inhibiting of the formation face failure includes communicating a proppant into the well bore via the string until a well bore pressure exceeds a first formation stress of the non-producing layer, which causes a fracture to form in the non-producing layer, and communicating the proppant into the fracture to create a barrier layer.
Patent CA-2648721-A1 (CA)
Inventor: BOBBIN JOSEPH
IPC: F21L4/00
Filed: 2009-01-12
Abstract: A cap lamp system features a battery pack, a cap lamp housing containing a cap lamp bulb and a power cord connected between the battery pack and the cap lamp housing. The power cord provides power to the cap lamp bulb from the battery pack. An electronic module includes a housing defining a chamber and electronic circuitry is positioned within the chamber of the housing. The electronic module is positioned in circuit with the power cord. The electronic module may receives power from the battery pack and the electronic circuitry of the electronic module may includes a battery that powers the module.
Patent CA-2658232-A1 (CA)
Inventor: LEGARDA IBANEZ JUAN JOSE
IPC: A61K31/5517
Filed: 2007-07-11
Abstract: The invention relates to the use of flumazenil for the production of a medicament for the treatment of depressive disorders, for example disorders including depressive symptoms, without psychotic alteration. The flumazenil can be administered sequentially in small quantities at short intervals until a quantity that is therapeutically effective for the treatment of the depressive disorder has been administered.
Patent CA-2660524-A1 (CA)
Inventor: SUN LIJUN
IPC: C07C327/56
Filed: 2007-08-20
Abstract: Disclosed are compounds of formulae (I), (III), (IV), (VII), (X), (XI), (XII), (XIII) and (XIV), wherein the variabables are as defined in the claims, and methods of using compounds of the invention for treating a subject with a proliferative disorder, such as cancer, and methods for treating disorders responsive to Hsp70 induction and/or natural killer induction. Also disclosed are pharmaceutical compositions comprising compounds of the invention and a pharmaceutically acceptable carrier.
Patent CA-2662957-A1 (CA)
Inventor: GUGLIELMETTI CRISTIANO
IPC: F25D29/00
Filed: 2007-10-15
Abstract: L' invention porte sur une méthode de contrôle et de gestion d'une instal lation de cryoconservation comprenant au moins un récipient ou au moins un r éfrigérateur (3,4), dans lequel ou lesquels sont disposés, dans une atmosphè re réfrigérée, des échantillons à conserver, ledit au moins unrécipient ou r éfrigérateur (3,4) étant disposé dans au moins un local (A). Selon cette mét hode, on opère un contrôle, de préférence à distance, avec recueil d'une ou plusieurs données issues ou représentatives d' au moins un récipient et/ou r éfrigérateur (3,4) contenant les échantillons de manière à vérifier l' état du fluide cryogénique qui y est présent ou de l' alimentation électrique dud it récipient et/ou réfrigérateur (3,4), de l état du moyen d ouverture/ferme ture dudit récipient et/ou réfrigérateur (3,4), ou de la température régnant dans ledit récipient et/ou réfrigérateur (3,4),d une ligne d' alimentation (2) de fluide cryogénique reliant au moins un réservoir (1) à au moins un ré cipient et/ou réfrigérateur (3,4), d'au moins une vanne agencée sur ladite l igne d' alimentation (2), ou dudit réservoir (118) contenant le fluide cryog énique, d' au moins une condition ambiante régnant dans le local (A), ou des échantillons conservés. Aumoins une partie des données recueillies sont ass ociées aux échantillons et mémorisées de manière associée aux échantillons. Système associé.
Patent CA-2663523-A1 (CA)
Title: Novel gene disruptions, compositions and methods relating thereto
Inventor: RANGEL CAROLINA
IPC: A61K38/00
Filed: 2007-10-01
Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO1105, PRO1279 or PRO1783 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities.
Patent CA-2663662-A1 (CA)
Inventor: WILLEN DENNIS E
IPC: G01V3/00
Filed: 2007-07-30
Abstract: Method for rapid inversion of data from a controlled-source electromagnetic survey of a subterranean region. Selected (51) common-receiver or common-source gathers of the data are reformed into composite gathers (52) by summing their data. Each composite gather is forward modeled (in the inversion process) with multiple active source locations (53). Computer time is reduced in proportion to the ratio of the total number of composite gathers to the total number of original common-receiver or common-source gathers. The data may be phase encoded to prevent data cancellation. Methods for mitigating loss of far offset information by data overlap in the summing process are disclosed.
Patent CA-2663757-A1 (CA)
Inventor: WANG DEAN CHIEN
IPC: C10G2/00
Filed: 2007-09-17
Abstract: A process for the manufacture of carbon disulphide comprising the following steps : (a) reacting carbon monoxide with hydrogen sulphide to form carbonyl sulphide and hydrogen; (b) contacting the carbonyl sulphide formed in step (a) with a catalyst effective for disproportionating carbonyl sulphide into carbon disulphide and carbon dioxide.
Patent CA-2665870-A1 (CA)
Title: Systems and methods for step discontinuity removal in real-time pcr fluorescence data
Inventor: BALDANZA JONATHAN M
IPC: G16B25/20
Filed: 2009-05-12
Abstract: The present invention relates to systems and methods for removing jump discontinuities in PCR or growth data.
Patent CA-2668530-A1 (CA)
Inventor: POTTERFIELD RUSSELL A
IPC: B25B23/144
Filed: 2007-11-05
Abstract: Torque adjusting drive systems and packaged torque adjusting drive systems are disclosed herein. One aspect of the disclosure is directed to systems and torque adjusting drivers for specific firearm-related work tasks. In one embodiment, a torque adjusting drive system includes a torque adjusting driver. The driver includes a shaft assembly having a fastener coupling portion and a handle. The driver also includes a torque adjusting mechanism for setting a user-selected torque value and a torque value indicator mounted on the driver for displaying at least the user-selected torque value. In addition to the driver, the system also includes a plurality of fastener interfacing attachments configured to couple to the fastener coupling portion and for driving one or more target fasteners. The system further includes a torque guide having a plurality of representative indicia of the target fasteners, wherein the torque guide communicates recommended torque value settings for the target fasteners.
Patent CA-2669399-A1 (CA)
Title: Thienopyrimidinones for treatment of inflammatory disorders and cancers
Inventor: WHITE STEPHEN L
IPC: A61K31/519
Filed: 2007-11-13
Abstract: The current invention provides compounds of formula (1): wherein: one of Q1, Q2 and Q3 is S, and the other of two of Q1, Q2 and Q3 are -CR1-, which are inhibitors of PI3K-delta. These compounds are useful for treatment of conditions mediated by PI3K-delta, such as hematopoietic cancers, immune disorders, and bone resorption disorders. The invention further provides pharmaceutical compositions comprising a compound of formula (1) and methods of using these compounds and compositions to treat conditions mediated by PI3K-delta.
Patent CA-2669853-A1 (CA)
Title: Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents
Inventor: FARINA CARLO
IPC: A61P25/02
Filed: 2007-11-14
Abstract: The use of a compound of formula (I), is disclosed in treating and/or preventing 5 chemotherapy-induced peripheral neurotoxicity (CIPN). The invention includes pharmaceutical compositions wherein the compound of formula (I) is present in a mixture with anticancer agents. An improved anticancer treatment with reduced CIPN-related side effects is also provided.
Patent CA-2670236-A1 (CA)
Inventor: FRINCKE JAMES M
IPC: A61K45/06
Filed: 2000-09-28
Abstract: The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods and compositions suitable for therapeutic applications.
Patent CA-2671247-A1 (CA)
Inventor: SLAUGHTER RICKY
IPC: G01N33/00
Filed: 2006-12-01
Abstract: A storage tank leak detection system, including a quartz crystal type pressure transducer held at a constant temperature, a bubbler-based pressure sensor for reporting tank bottom pressure measurements to the transducer, a fluid surface measurement apparatus to report liquid surface pressure to the transducer, atmospheric pressure measuring apparatus, and a computing system for, based on data reported by all components, effecting data correction (corrected for atmospheric and container physical variations during data gathering) and regression techniques to yield data indicative of changes, if any, in mass content of a liquid storage container, such as a surface storage tank for petroleum and other chemicals.
Patent CA-2673956-A1 (CA)
Title: Method, network system and destination network for transmitting qos during a handover process between systems
Inventor: HU WEIHUA
IPC: H04W28/24
Filed: 2008-02-01
Abstract: A method for transmitting quality of service (QoS) during a handover process between systems and a network system and a destination network thereof are provided, which enable the QoS to be transmitted to a second access network during a handover process of a user equipment (UE) between systems. The method comprises: a second network mobility management network element acquires QoS of a UE during a handover process of the UE  from a first network to a second network; and the second network mobility management network element transmits the acquired QoS to the second network access network and/or a user plane network element.
Patent CA-2675984-A1 (CA)
Inventor: MAGUIRE CHRISTOPHER
IPC: G06Q30/00
Filed: 2008-01-22
Abstract: A system and method for selling product is provided. In accordance with one aspect, shoppers using an Internet-based commerce site may request custom designed products rather than mass produced products from willing sellers. Shoppers may provide terms under which the custom good must be manufactured. Various systems and methods may also provide a platform for shoppers and sellers to negotiate terms and/or to incorporate negotiated terms into such requests. According to some embodiments, the system and method for selling product facilitates fabrication, delivery and payment for customized goods. In one embodiment, requests for customized goods may be fulfilled by multiple sellers. One example includes multiple sellers fulfilling a custom request, and another includes multiple sellers each producing a part of a desired quantity for a custom request, among other options. One aspect also includes allowing shoppers to request custom made products from one or more manufacturers. One aspect includes placing a public request for bids to manufacture a custom product and accepting offers from manufacturers to fulfill the bids.
Patent CA-2678610-A1 (CA)
Inventor: LEHMAN AMY
IPC: G06F3/033
Filed: 2007-12-31
Abstract: A surgical device (10) includes a console (12) having a visual display (24) and a manipulator arm (26A,26B), a robotic device (14) having a camera (66) and a connection component. The robotic device is configured to be positioned completely within a body cavity. The camera is configured to transmit visual images to the visual display. The connection component operably couples the console and the robotic device. The manipulator arm is positioned relative to the visual.display so as to appear to be penetrating the visual display.
Patent CA-2679278-A1 (CA)
Title: Signal quality determination in cable networks
Inventor: BOSCHMA JEROEN JACOB
IPC: H04B3/46
Filed: 2008-02-27
Abstract: A method of determining signal quality in a cable network comprises the steps of: providing a network model (1) comprising an interconnection model (2) and component models (3), providing an input signal (IS), determining an output signal (OS) using the input signal and the network model, and determining the signal quality from the input signal (IS) and the output signal (OS). The input signal (IS) comprises multiple constituent signal components, each signal component representing a class of input signals. The step of determining the output signal involves determining intermodulations of the constituent signal components by effecting frequency domain convolutions of the spectra of the constituent signal components.
Patent CA-2679331-A1 (CA)
Title: Selective phase connection establishment
Inventor: KITAZOE MASATO
IPC: H04W8/24
Filed: 2008-03-20
Abstract: Systems and methodologies are described that facilitate multiple-phase selective connection establishment in wireless communications networks. Radio resource control (RRC) layer communications can be instantiated between a mobile device and base station. Additional information can be required by a downstream network component regarding the mobile device. Accordingly, the RRC resources can be utilized to transmit the additional information from the mobile device to the network component to facilitate the multiple-phase establishment. This can be accomplished using non-access stratum (NAS) messages. Further, the information can relate to authorization, security re-configuration, context re-synchronization, an identity of the mobile device, and the like.
Patent CA-2679842-A1 (CA)
Title: Methods for applying solution catalysts to reactor surfaces
Inventor: STAVENS KEVIN B
IPC: C08F2/00
Filed: 2008-02-21
Abstract: A method for treating at least one interior surface (for example, a bed wall) of a fluidized bed polymerization reactor system, including by applying a solution catalyst (preferably at least substantially uniformly and in liquid form) to each surface, and optionally (where a catalyst component of the solution catalyst comprises at least one chromium containing compound) oxidizing at least some of the applied chromium containing compound in a controlled manner.
Patent CA-2681767-A1 (CA)
Title: Using accounting data based indexing to create a portfolio of financial objects
Inventor: ARNOTT ROBERT D
IPC: G06Q40/00
Filed: 2008-03-21
Abstract: A system, method and computer program product creates an index based on accounting based data, as well as a portfolio of financial objects based on the index where the portfolio is weighted according to accounting based data. A passive investment system may be based on indices created from various metrics. The indexes may be built with metrics other than market capitalization weighting, price weighting or equal weighting. Non-financial metrics may also be used to build indexes to create passive investment systems. Additionally, a combination of financial non-market capitalization metrics may be used along with non-financial metrics to create passive investment systems. Once the index is built, it may be used as a basis to purchase securities for a portfolio. Specifically excluded are widely-used capitalization-weighted indexes and price-weighted indexes, in which the price of a security contributes in a substantial way to the calculation of the weight of that security in the index or the portfolio, and equal weighting weighted indexes. Valuation indifferent indexes avoid overexposure to overvalued securities and underexposure to undervalued securities, as compared with conventional capitalization-weighted and price-weighted.
Patent CA-2682089-A1 (CA)
Inventor: MUELLER STEFFEN
IPC: A61K39/13
Filed: 2008-03-31
Abstract: This invention provides an attenuated virus which comprises a modified vi ral genome containing nucleotide substitutions engineered in multiple locati ons in the genome, wherein the substitutions introduce synonymous deoptimize d codons into the genome. The instant attenuated virus may be used in a vacc ine composition for inducing a protective immune response in a subject. The invention also provides a method of synthesizing the instant attenuated viru s. Further, this invention further provides a method for preventing a subjec t from becoming afflicted with a virus-associated disease comprising adminis tering to the subject a prophylactically effective dose of a vaccine composi tion comprising the instant attenuated virus.
Patent CA-2682981-A1 (CA)
Title: Imidazo[1,2-a]pyridine compounds as receptor tyrosine kinase inhibitors
Inventor: RIZZI JAMES P
IPC: A61K31/33
Filed: 2008-03-27
Abstract: Compounds of Formula I: in which A, B, R1, R1a, R2, R3, R4, R5 R6, R7 and R8 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by class 3 and class 5 receptor tyrosine kinases. Particular compounds of this invention have also been found to be inhibitors of Pim-1.
Patent CA-2683738-A1 (CA)
Title: Indanone derivatives that inhibit prolyl hydroxylase
Inventor: REED ANTHONY B
IPC: C07C235/04
Filed: 2008-04-09
Abstract: Compounds of Formula I are useful inhibitors of HIF prolyl hydroxylases. Compounds of Formula I have the following structure: where the definitions of the variables are provided herein.