baber/WOPTO huggingface dataset:
Patent WO-2019094268-A1 (WO)
Title: Compositions et procédés d'utilisation de l'interleukine-10 en association avec des inhibiteurs de voies de points de contrôle immunitaire
Inventor: OFT MARTIN
IPC: A61K38/20
Filed: 2018-11-02
Abstract: La présente invention concerne un procédé pour le traitement d'une maladie néoplasique chez un sujet mammifère, le procédé comprenant l'administration d'un agent IL-10 en association avec l'administration d'au moins un modulateur d'au moins une voie de point de contrôle immunitaire. La présente invention concerne en outre un procédé pour le traitement d'une maladie néoplasique, le néoplasme présentant une charge mutationnelle tumorale faible ou intermédiaire, un niveau faible ou intermédiaire d'expression de la molécule de point de contrôle immunitaire ou une maladie néoplasique métastasique.
Patent WO-2019090031-A1 (WO)
Inventor: BARRERA OSVALDO ANDRES
IPC: A61B34/20
Filed: 2018-11-02
Abstract: La présente invention concerne un système de visualisation et de suivi chirurgical qui comprend des premier et second aimants de suivi et un ensemble de base de capteur comprenant un socle et au moins trois ensembles de capteurs magnétiques. Chacun des ensembles de capteurs magnétiques est configuré pour suivre indépendamment chacun des aimants de suivi dans les dimensions X, Y et Z. Une console de commande est configurée pour recevoir des données de suivi de chacun des ensembles de capteurs magnétiques et déterminer des informations de position et d'orientation pour chacun des aimants de suivi sur la base des données de suivi reçues. Un système de visualisation est configuré pour recevoir les informations de position et d'orientation à partir de la console de commande et représenter les informations de position et d'orientation pour chacun des premier et second aimants de suivi sur un modèle 3D affiché de tissu.
Patent WO-2019094408-A1 (WO)
Title: Procédé de préparation d'une composition d'assouplissant textile par dilution d'un prémélange d'assouplissant textile concentré
Inventor: SAVEYN PIETER
IPC: C11D3/00
Filed: 2018-11-07
Abstract: La présente invention concerne un procédé de préparation d'une composition d'assouplissant textile liquide par dilution d'un prémélange d'assouplissant textile concentré comprenant un agent actif d'assouplissant textile à base d'ester d'ammonium quaternaire et de la cellulose microfibreuse. Le procédé de préparation de l'assouplissant textile selon la présente invention permet d'obtenir des compositions d'assouplissant textile présentant un aspect riche avec une complexité de fabrication réduite.
Patent WO-2019099861-A1 (WO)
Inventor: NISTRO GABRIEL
IPC: A61K47/66
Filed: 2018-11-16
Abstract: Disclosed herein are compositions comprising complexes of cyclodextrins and lipid-modified stem cell proteins. Also disclosed are topical compositions the complexes. Methods of using the compositions for the therapeutic purposes are also disclosed as well as methods of producing the compositions.
Patent WO-2019118742-A1 (WO)
Title: Récipient de réception modulaire de grande capacité et procédés associés
Inventor: LANIGAN MATTHEW STEPHEN
IPC: B65D88/52
Filed: 2018-12-13
Abstract: L'invention concerne un récipient de réception, comprenant une pluralité de panneaux de support de charge, enchevêtrés de manière amovible, préformés, conçus pour former une paroi de support de charge, au moins partiellement incurvée, s'étendant autour du périmètre d'au moins une zone de stockage pouvant contenir au moins 100 000 gallons de liquides, de solides ou d'une association de ces derniers. La largeur et/ou la longueur de chaque panneau sont inférieures à 102 pouces lorsque les panneaux ne sont pas à l'état de support de charge.
Patent WO-2019135879-A1 (WO)
Title: Macrophages modifiés et précurseurs de macrophages et méthodes associées
Inventor: O'NEILL KIM
IPC: A61P31/00
Filed: 2018-12-13
Abstract: L'invention concerne des macrophages ou des cellules précurseurs de macrophages dépourvus d'expression fonctionnelle de gènes du CMH. Les macrophages peuvent exprimer HLA-G ou un gène du CMH modifié qui ne déclenche pas une réponse immunitaire chez un sujet allogène mais reste reconnu par les cellules NK. Les cellules peuvent en outre comprendre un récepteur d'antigène chimérique.
Patent WO-2019126153-A1 (WO)
Title: Dispositif de lutte contre les animaux nuisibles
Inventor: EDEVOLD MARK
IPC: A01M23/16
Filed: 2018-12-18
Abstract: Dispositif destiné à piéger un rongeur comprenant un ou plusieurs éléments parmi un plancher, des parois reliées au plancher, une ouverture dans au moins l'une des parois, et une plateforme positionnée dans le contenant. La plateforme est positionnée adjacente à l'ouverture et élevée au-dessus du plancher. Un adhésif est positionné sur le plancher. L'ouverture est dimensionnée pour permettre à un rongeur d'accéder à la plateforme.
Patent WO-2019136191-A1 (WO)
Inventor: DUAN GANG
IPC: C09D15/00
Filed: 2019-01-04
Abstract: The present invention relates to use of an aqueous dispersion of vinylidene chloride- acrylic acid-vinyl chloride terpolymer as a barrier coating in wood substrates. In particular, the present invention relates to an article comprising (a) a wood substrate comprising at least one of tannin and rosin; (b) a primer coat directly applied on a major surface of the wood substrate, formed from a water borne clear paint comprising an aqueous dispersion of vinylidene chloride-acrylic acid-vinyl chloride terpolymer; and (c) one or more light- colored topcoat applied on the primer coating.
Patent WO-2019143595-A1 (WO)
Title: Radio frequency sensor system incorporating machine learning system and method
Inventor: RAGALLER PAUL A
IPC: G01R1/067
Filed: 2019-01-15
Abstract: A radio frequency sensor system comprising a housing defining a resonant cavity. Radio frequency probe(s) in the cavity transmit and/or receive radio frequency signals. A radio frequency control unit is in communication with the radio frequency probe(s) for determining one or more states of the radio frequency sensor system based on changes in the characteristics of the radio frequency signals. A machine learning system is in communication with the radio frequency control unit for identifying and developing transfer functions and calibrations based on the changes in the characteristics of the radio frequency signals and determining the one or more states of the radio frequency sensor system.
Patent WO-2019152361-A1 (WO)
Title: Dynamic contact angle measurement
Inventor: ALSHEHRI AMAR JABER M
IPC: G01N33/24
Filed: 2019-01-29
Abstract: A contact angle measurement system includes a housing that can hold a volume of a first fluid having a first density, an adjustable rock sample holder positioned within the housing, a fluid dropper attached to the housing, an image capturing a device, and a computer system. The holder can support a rock sample. An orientation of the holder relative to the housing is adjustable such that an outer surface of the rock sample is at a non-zero angle relative to a lower wall of the housing. When the orientation of the holder relative to the housing is such that the outer surface of the rock sample is at the non-zero angle relative to the lower wall, the fluid droplet traverses the outer surface of the rock sample. The image capturing device can capture images of the fluid droplet as the fluid droplet traverses the outer surface of the rock sample.
Patent WO-2019216964-A1 (WO)
Title: Providing composite graphical assistant interfaces for controlling various connected devices
Inventor: NI YUZHAO
IPC: H04L12/28
Filed: 2019-02-01
Abstract: Methods, apparatus, systems, and computer-readable media are provided for tailoring composite graphical assistant interfaces for interacting with multiple different connected devices. The composite graphical assistant interfaces can be generated in response to a user providing a request for an automated assistant to cause a connected device to perform a particular function. In response to the automated assistant receiving the request, the automated assistant can identify other connected devices, and other functions capable of being performed by the other connected devices. The other functions can then be mapped to various graphical control elements in order to provide a composite graphical assistant interface from which the user can interact with different connected devices. Each graphical control element can be arranged to reflect how each connected device is operating simultaneous to the presentation of the composite graphical assistant interface.
Patent WO-2019157004-A1 (WO)
Title: Cochlear implant localization system
Inventor: TSAY ISHAN ANN
IPC: A61N1/05
Filed: 2019-02-06
Abstract: A navigation system or combination of navigation systems can be used to provide one or more navigation modalities to track a position and navigate a single instrument in a volume. For example, both an Electromagnetic (EM) and Electropotential (EP) navigation system can be used to navigate an instrument within the volume. The two navigation systems may be used separately to selectively individually navigate the single instrument in the volume. Disclosed are also systems and processes to determine a shape of the single instrument either alone or in combination with the position of the instrument. The instrument may be navigated with the addition of tracking devices or with native or inherent portions of the instrument.
Patent WO-2019160826-A1 (WO)
Title: Linerless water-activated water-based emulsion
Inventor: JADHAV DIPAK
IPC: C08F263/04
Filed: 2019-02-12
Abstract: Provided herein is a water-activated adhesive comprising an aqueous emulsion of vinyl acetate, polyvinyl alcohol, and glycerin. The adhesive has no significant tack prior to being activated, can be repositionable for at least 1 minute after activation, and can form a strong bond less than two hours after activation. Also provided are labels comprising the water-activated adhesive, methods for producing and using the water- activated adhesive, and systems for labeling articles with the water-activated adhesive.
Patent WO-2019177932-A1 (WO)
Title: Fagopyrum nutraceutical compositions
Inventor: WANG LU
IPC: A61P1/16
Filed: 2019-03-11
Abstract: Fagopyrum dibotyo  nutraceuticals and methods of their use are provided. The disclosed  F. dibotyo  nutraceuticals are useful to improve or increase liver function and to treat liver diseases, especially those caused by viral hepatitis. In some embodiments, the  F. dibotyo  nutraceuticals also contain supplementary botanical extracts to confer additional health benefits.
Patent WO-2019209433-A1 (WO)
Title: Plasma-enhanced chemical vapor deposition of carbon hard-mask
Inventor: Kwon byung seok
IPC: H01L21/311
Filed: 2019-03-21
Abstract: In one or more embodiments, a method for depositing a carbon hard-mask material by plasma-enhanced chemical vapor deposition (PECVD) includes heating a substrate contained within a process chamber to a temperature in a range from about 100C to about 700C and producing a plasma with a power generator emitting an RF power of greater than 3 kW. In some examples, the temperature is in a range from about 300C to about 700C and the RF power is greater than 3 kW to about 7 kW. The method also includes flowing a hydrocarbon precursor into the plasma within the process chamber and forming a carbon hard-mask layer on the substrate at a rate of greater than 5,000 /min, such as up to about 10,000 /min or faster.
Patent WO-2019190888-A1 (WO)
Inventor: KLEIN CHRISTIAN
IPC: G06F3/0484
Filed: 2019-03-21
Abstract: A technique is described herein for helping a user move a source object that appears on a user interface presentation to a target destination. The technique involves performing semantic analysis on both the source object and at least one candidate target destination. The semantic analysis yields a score that reflects the relationship between the source object and the candidate target destination. The technique then presents a representation of the candidate target destination that is visually enhanced to an extent that is dependent on its output score. The technique then allows the user to move the source object to a representation of a selected target destination, whereupon it becomes associated with the target destination. The technique can produce the enhanced representation by changing a characteristic of an on-screen target identifier (that already exists on the user interface presentation), or by displaying a transient target identifier.
Patent WO-2019217084-A1 (WO)
Title: Suspension system and method for controlling suspension system
Inventor: GOLIN MICHAEL
IPC: H02J50/90
Filed: 2019-04-25
Abstract: A suspension system (106, 108) for a vehicle (100) is provided. The vehicle (100) is travelling on a substrate (S). The suspension system (106, 108) includes a plurality of dampers (112) and a controller (120) disposed in communication with the plurality of dampers (112). The controller (120) is configured to determine that a receiving coil (124) disposed on the vehicle (100) is inductively receiving electrical energy from a transmitting coil (126). The transmitting coil (126) is disposed on or below the substrate (S). The controller (120) is further configured to control a damping level of each of the plurality of dampers (112) to maintain a distance between the receiving coil (124) and the transmitting coil (126) within a predetermined range or at a constant value.
Patent WO-2019217342-A1 (WO)
Title: Tow cable system and method of use
Inventor: GALLO MICHAEL
IPC: B64D3/00
Filed: 2019-05-06
Abstract: A tow cable system and method of use wherein, in the context of towed flight of a glider behind an aircraft, positive load or tension of the cable therebetween is achieved through one or more of cable design and material selection, cable pre-tensioning, in-flight cable tensioning, and/or load dampening device(s), and the related interplay of such various components or sub-systems of the overall tow cable system.
Patent WO-2019226744-A1 (WO)
Title: Power supplies and methods of using miniaturized intra-body controllable medical device
Inventor: VELIS CHRISTOPHER J P
IPC: A61L27/28
Filed: 2019-05-22
Abstract: A medical device for intra-body conveyance includes a host structure defining an interior area and at least one power supply. The power supplies can include miniaturized batteries, fuel cells, electrochemical reactors, piezoelectric devices, energy harvesting devices that obtains thermal and/or chemical reaction energy from the fluids in and tissue of the lumen and adjacent organs, thermal reactors, heat absorption energy conversion devices and triboelectric energy harvesting devices.
Patent WO-2020010118-A1 (WO)
Title: Methods of treating or selecting a treatment for a subject resistant to tnf inhibitor using a nlrp3 antagonist
Inventor: FRANCHI LUIGI
IPC: A61K31/34
Filed: 2019-07-02
Abstract: Provided herein are methods of treating a subject that include administering a therapeutically effective amount of an NLPR3 antagonist or a pharmaceutically acceptable salt, solvate, or co-crystal thereof to a subject identified as having a cell that has an elevated level of NLRP3 inflammasome activity and/or expression as compared to a reference level. Provided herein are methods of treating a subject, methods of selecting a treatment for a subject, methods of selecting a subject for treatment, and methods of selecting a subject for participation in a clinical study that include the administration of a therapeutically effective amount of an NLRP3 antagonist. Also provided are methods of treating a subject having resistance to an anti-TNFa agent and methods of determining the efficacy of treatment with an anti-TNFα agent. Also provided are methods of treating a subject with a combination of an NLRP3 antagonist and an anti-TNFα agent.
Patent WO-2020036959-A1 (WO)
Title: Machine learning system and methods for determining confidence levels of personal information findings
Inventor: ENUKA YEHOSHUA
IPC: G06N5/04
Filed: 2019-08-13
Abstract: Privacy management platforms are disclosed herein to scan any number of data sources in order to provide users with visibility into stored personal information, risk associated with storing such information and/or usage activity relating to such information. The platforms may correlate personal information findings to specific data subjects and may employ machine learning models to classify findings as corresponding to a particular personal information attribute to provide an indexed inventory across multiple data sources.
Patent WO-2020051526-A1 (WO)
Title: Microbiome-based tracking system and methods relating thereto
Inventor: CADLE-DAVIDSON MOLLY
IPC: G16B20/00
Filed: 2019-09-06
Abstract: The present invention relates generally to a system and method to identify an origin of one or more products by comparing its microbial composition to known location microbiomes present in a database. The microbiome associated with a single location, such as a farm, should have common elements that differ from all other farms due to a variety of factors including on-farm livestock mix, human inhabitants, soil, water sources, local plant life, climate and weather patterns, local wildlife and native insects, etc. Further inclusion of the microbiome present all along the entire processing and distribution chain will be unique and identifiable due to similar factors as listed above. Methods for metagenomic and microbiome analyses have dramatically improved, making the application of this technology to agricultural product identification and safety a realistic endeavor.
Patent WO-2020055824-A1 (WO)
Title: Dry powder formulation of caveolin-1 peptides and methods of use thereof
Inventor: WILLIAMS ROBERT
IPC: C07K7/06
Filed: 2019-09-10
Abstract: Provided herein are compositions comprising caveolin-1 (Cav-1) peptides. Further provided are methods of using the Cav-1 peptides for the treatment of lung infections or acute or chronic lung injury, particularly lung fibrosis.
Patent WO-2020086416-A1 (WO)
Title: Inhibiteurs du facteurs xia
Inventor: ALI AMJAD
IPC: C07D401/14
Filed: 2019-10-21
Abstract: La présente invention concerne un composé de formule (I) et des compositions pharmaceutiques comprenant un ou plusieurs desdits composés, et des procédés d'utilisation desdits composés pour traiter ou prévenir des thromboses, des embolies, une hypercoagulabilité ou des changements fibrotiques. Les composés sont des inhibiteurs sélectifs du facteur XIa ou des inhibiteurs doubles du facteur XIa et de la kallicréine plasmatique.
Patent WO-2020096935-A1 (WO)
Inventor: LI YUNKUI
IPC: C01B39/48
Filed: 2019-11-04
Abstract: A method of forming AEI-type zeolites in a hydrothermal synthesis without the use of hydrogen fluoride (HF) and in the presence of an FAU zeolite NaY with SAR ≤ 5, a Y zeolite with a SAR ≥ 5, or a combination thereof. A gel composition formed upon using this method includes one or more sources of silica, alumina, organic structure directing agents (OSDA), and alkali metal ions; zeolite seeds; and water. This gel composition is defined by the molar ratios of: SiO 2 /AI 2 O 3  18:1 to 100:1; M 2 O/SiO 2  0.15:1 to 0.30:1; ROH/SiO 2  0.05:1 to 0.13:1; and H 2 O/SiO 2  5:1 to 20:1; wherein M is the alkali metal ion and R is an organic moiety derived from the OSDA. This gel composition, after reacting at a temperature between 135°C to about 200°C for 10 hours to 168 hours forms the crystalline AEI-type zeolite having a silica to alumina ratio (SiO 2 :AI 2 O 3 ) that is greater than 15:1.
Patent WO-2020097455-A1 (WO)
Inventor: GKIKAS MANOS
IPC: A61K47/64
Filed: 2019-11-08
Abstract: A complex includes an amyloid peptide complexed with a cholinesterase inhibitor, an NMDA receptor antagonist, or a combination, of a cholinesterase inhibitor and an NMDA receptor antagonist, wherein the amyloid peptide comprises X 1 X 2 GAIIGX 3 X 4  (SEQ ID NO: 2), wherein X 1  and X 4  are each independently YF or FY, and X 2  and X 3  are each 1 amino acid long, and are each independently T, N, S, or Q; or X 2  and X 3  are each 2 amino acid long and X 2  is (Y or F)T, (Y or F)N, (Y or F)S or (Y or F)Q, and X 3  is T(Y or F), N(Y or F), S(Y or F) or Q(Y or F), wherein the amyloid peptide self-assembles into amyloid fibrils, and wherein the peptide has a total length of 11-13 amino acids.
Patent WO-2020102680-A1 (WO)
Title: Antibody-based therapeutics for targeting htra1 and methods of use
Inventor: LAUDER SCOTT
IPC: C07K16/40
Filed: 2019-11-15
Abstract: The present disclosure provides compositions and methods for treating, preventing, or inhibiting diseases of the eye. In one aspect, the disclosure provides anti-HTRA1 antibodies or antigen-binding fragments and methods of using the same.
Patent WO-2020106846-A1 (WO)
Inventor: SUBRAMANIAN AZHAGU
IPC: B60Q1/30
Filed: 2019-11-20
Abstract: A system for modifying the structure of a unibody vehicle includes a vehicle body having a unibody construction and a first module attached to the vehicle body. The first module is removable from the vehicle body and replaceable with a second module having a different size and/or functionality. A rear portion of the first module may be removed from the first module and attached to the second module. The first module may be a stock cargo module, and the second module may be an aftermarket module. The rear portion may be a stock tail tamp and/or sensor module. The rear portion may be removed before or after removing the first module from the vehicle body, and may be attached to the second module before or after attaching the second module to the vehicle body.
Patent WO-2020117816-A1 (WO)
Inventor: SCHERBAKOV EUGENE
IPC: H01S5/40
Filed: 2019-12-03
Abstract: The disclosed ultra-high power all fiber laser system is configured with multiple spaced apart fiber lasers outputting respective laser beams respective paths. The disclosed system is further configured with a tapered fiber-bundle including at least, one central guiding fiber and a plurality of peripheral guiding fibers. The disclosed system further has a multiclad delivery fiber configured with a double-bottle neck cross-section and provided with at least two concentric and radially spaced apart inner and outer cores. The inner core is coupled to the peripheral guiding fibers while the inner core is spliced to the central guiding fiber so that a system output emitted from the inner core of the delivery fiber has a different beam shape from the system output emitted from the outer core.
Patent WO-2020118225-A1 (WO)
Title: Motors for downhole tools devices and related methods
Inventor: TYSHKO ALEXEY
IPC: E21B4/02
Filed: 2019-12-06
Abstract: A motor includes one or more actuator, one or more one passive members, and one or more pushing members. The actuator(s) vibrate along a first axis. The vibrations vary a dimension of the actuator(s) as measured along the first axis. The passive member(s) rotate around a second axis that is substantially parallel to the first axis. The pushing member(s) are positioned between the actuator(s) and the passive member(s). The pushing member(s) are fixed to the actuator(s) and have a contact surface frictionally engaging and applying a mechanical force to the passive member (s). The pushing member(s) have an asymmetric rigidity along the first axis. The motor and a power consumer may be conveyed into a wellbore. The motor may be energized to supply mechanical power to the power consumer.
Patent WO-2020131806-A1 (WO)
Title: Wound dressings including pvp-citric acid copolymer
Inventor: LOCKE CHRISTOPHER B
IPC: A61L26/00
Filed: 2019-12-17
Abstract: Dressings which may be useful in disrupting and/or preventing biofilm formation in a wound upon application are described, where the dressings of the present technology include a co-polymer of polyvinylpyrrolidone (PVP) and citric acid. Also disclosed herein methods employing such dressings as well as kits including such dressings.