baber/WOPTO huggingface dataset:
Patent CO-6241111-A2 (CO)
Title: Derivados de la espirociclopropil piperidina
Inventor: BERNSTEIN PETER
IPC: C07D405/04
Filed: 2009-11-11
Abstract: 1.- Un compuesto de fórmula I, sus enantiómeros, sus sales farmacéuticamente aceptables, o sus mezclas:donde:R1 es arilo, heteroarilo, arilalquilo, heteroarilalquilo, cicloalquilo, heterocicloalquilalquilo, alquilo, alcoxialquilo, hidroxialquilo, aminoalquilo, aminocarbonilalquilo, heterociclo, arilalquenilo o heterocicloalquilo; donde R1 está opcionalmente sustituido con al menos un sustituyente seleccionado independientemente entre alquilo, ciano, sulfinilo, haloalquilo, amida, alcoxi, halógeno, arilalcoxi, alquilcarbonilo, carboxi (-C(=O)OH), hidroxi (-OH), amino, alcoxicarbonilo y alquilsulfonilo; y R2 es arilo, heteroarilo, cicloalquilo, alquilo, heterocicloalquilo o cicloalquilalquilo; donde R2 está opcionalmente sustituido con al menos un sustituyente seleccionado independientemente entre C1-C6alquilo, alcoxi y cicloalquilo; con la condición de que: 1) cuando R2 sea un ciclohexilo, R1 no sea un fenilo sustituido ni sin sustituir; 2) cuando R2 sea arilo, R2 no sea un fenilo sin sustituir; y3) cuando R1 sea tetrahidropiran-4-ilo y R2 sea un fenilo sustituido, el fenilo sustituido no esté sustituido con metilo en la posición orto ni meta, ni sustituido con metoxi en la posición meta. 2.- Un compuesto de acuerdo con la reivindicación 1, donde R1 es arilo, heteroarilo, arilalquilo, cicloalquilo, heterocicloalquilalquilo, alquilo, arilalquenilo, heterociclo, o heterocicloalquilo;3.- Un compuesto de acuerdo con la reivindicación 1 o 2, donde R1 es C6-C14arilo, C6-C14heteroarilo, (C6-C14aril)-(C1-C6alquilo), C3-C8cicloalquilo, (C3-C8heterocicloalquil)-(C1-C6alquilo), C1-C6alquilo (C6-C14aril)-(C1-C6alquenilo) o C3-C8heterocicloalquilo.4.- Un compuesto de acuerdo con cualquiera de las reivindicaciones 1 ó 2, donde R1 está sustituido con al menos un sustituyente seleccionado independientemente entre alquilo, haloalquilo, amida, alcoxi, halógeno, arilalcoxi, alcoxicarbonilo y alquilsulfonilo. 5.- Un compuesto de acuerdo con cualquiera de las reivindicaciones 1-4, donde R1 está sustituido con al menos un sustituyente seleccionado independientemente entre C1-C6alquilo, haloC1-C6alquilo, amida, C1-C6alcoxi, halógeno, (C6-C14aril)-(C1-C6alcoxi), C1-C6alcoxicarbonilo y C1-C6alquilsulfonilo.
Patent CO-6251252-A2 (CO)
Title: Metabolitos de derivados del (tio)-carbamoil-ciclohexano
Inventor: AGAINE CSONGOR EVA
IPC: A61K31/495
Filed: 2009-12-16
Abstract: La presente invención se refiere a metabolitos de derivados del (tio)-carbamoil-ciclohexano, concretamente metabolitos de la trans-4-{2-[4-(2,3-diclorofenil-piperazin-1-il]-etil}-N,N-dimetilcarbamoil-ciclohexilamina y sales farmacéuticamente aceptables de la misma, para composiciones farmacéuticas que los contienen y para su uso en el tratamiento y/o prevención de trastornos que requieren la modulación de receptores de dopamina. 1.- Un metabolito aislado de un compuesto de fórmula (I):en la que R1 y R2 son cada uno, independientemente, hidrógeno, alquilo, alquenilo, arilo, cicloalquilo, amilo, o R1 y R2 forman un anillo heterocíclico con el átomo de nitrógeno adyacente; X es O o S; n es 1 o 2; y/o isómeros geométricos y/o estereoisómeros y/odiasterómeros y/o sales y/o hidratos y/o solvatos y/o formas polimórficas del mismo. 2.- Un metabolito aislado y/o sintetizado de un compuesto de fórmula (I) según la reivindicación 1, en el que el compuesto de fórmula (I) esy/o sales y/o hidratos y/o solvatos y/o formas polimórficas del mismo. 3.- Un compuesto aislado y/o sintetizado de fórmula (II):en la que R1 y R2 son cada uno, independientemente, hidrógeno, alquilo, alquenilo, arilo, cicloalquilo, aroilo, o R1 y R2 forman un anillo heterocíclico con el átomo de nitrógeno adyacente; X es O o S; n es 1 o 2; y/o isómeros geométricos y/o estereoisómeros y/o diasterómeros y/o sales y/o hidratos solvatos y/o formas polimórficas del mismo.
Patent CO-6251245-A2 (CO)
Title: Compuestos de prolina modificados con propiedades inhibitorias del virus de la hepatitis c
Inventor: CHO AESOP
IPC: A61K31/4025
Filed: 2009-12-18
Abstract: 1.- Un compuesto de formula I:o una sal farmacéuticamente aceptable, o profármaco del mismo, en donde:Y1 es O, S, o NR3; Y2 es O, S, o NR3; Z es O, S, o NR3;Z1 se selecciona de las siguientes estructuras:cada Ra es alquilo(C1-10), en donde uno o más átomos de carbono de dicho alquilo (C1-10) es opcionalmente reemplazado por O y cuyo alquilo(C1-10) está opcionalmente sustituido con uno o más heterociclilo y cuyo heterociclilo está opcionalmente sustituido con uno o más A3; cada Rb es R1, H, F, CI, Br, I, CF3, alquilo(C1-10), o XR3; cada Rc es R1, H, ciano, F, CI, Br, I, -C(=O)NRdRe, C(=O)NRsRt, NRsRt, S(=O)2NRsRt, alquilo(C1-10), alquenilo(C2-10), alquinilo(C2-10), alcoxi(C1-10), cicloalquilo, ORr, SRr, S(O)Rr, S(O)2Rr, arilo, o heteroarilo, cuyo alquilo(C1-10), alcoxi(C1-10), cícloalquilo, arilo o heteroarilo está opcionalmente sustituido con uno o más grupos seleccionados independientemente de halo, hidroxi, alquilo(C1-10), alquenilo(C2-10), alquinilo(C2-10), alcanoilo(C1-10), alcoxi(C1-10), alcanoiloxi(C1-10), alcoxi(C1-10)carbonilo, NRnRp; SRr, S(O)Rn o S(O)2Rr; Rd y Re son cada uno independientemente H o alquilo(C1-10); cada Rf es H, hidroxi, carboxi, ciano, alquilo(C1-10), alquenilo(C2-10), alquinilo(C2-10), alcanoilo(C1-10), alcoxi(C1-10), alcanoiloxi(C1-10), alcoxicarbonilo(C1-10), NRnRp, SRr, S(O)Rr, o S(O)2Rr; cada Rh es H, A3, C(=O)2NRsRt, o S(=O)2NRsRt; cada Rm es H, ciano, F, CI, Br, I, -C(=O)NRdRe, alcoxi(C1-10), cicloalquilo, o fenilo que está opcionalmente sustituido con uno o más F, CI, Br, I, alquilo(C1-10), o alcoxi(C1-10);cada L es independientemente CH o N; uno de E o D es O, S, o NRf t el otro E o D es CRh o N; Z2a es H, alquilo(C1-10), alquenilo(C2-10), ...
Patent CO-6300795-A2 (CO)
Title: Un vector adenovirico de simio para uso en una vacuna
Inventor: COHEN JOSEPH D
IPC: A61K39/00
Filed: 2010-06-10
Abstract: La invención se refiere a un vector adenovírico de simio deficiente de replicación C7 que codifica una proteína que comprende la proteína CS de P. falciparum o un fragmento de la misma, por ejemplo como se muestra en la SEC ID N° 1 o la SEC ID N° 3. La invención se refiere también a procedimientos de preparación de dicho vector vírico y al uso del vector vírico en el tratamiento/prevención de infección por malaria. Se describen también composiciones, vacunas y kits que comprenden dicho vector vírico. En un aspecto, la invención emplea un vector vírico C7 sintético. El vector vírico C7 según la invención puede coadministrarse o coformularse con un antígeno de la malaria tal como RTS,S, opcionalmente en presencia de un coadyuvante, por ejemplo, que comprende 3D-MPL y/o una saponina tal como QS21.
Patent CO-6541553-A2 (CO)
Title: Fluidos viscoelásticos a base de surfactante y método para usar los mismos
Inventor: PLASIER RONALD CASEY
IPC: C09K8/60
Filed: 2012-05-07
Abstract: Fluidos viscoelásticos a base de surfactante para mejorar la productividad de formaciones en cojinete de hidrocarburos que tiene aplicabilidad particular en el fracturamiento de formaciones subterráneas alrededor de pozos petroleros y de gas. El fluido viscoelástico contiene un ácido orgánico, una sal monovalente inorgánica y una sal aromática de amonio cuaternaris y agua. El fluido además puede estar espumado o energizado.
Patent CO-6551745-A2 (CO)
Title: Combinación de fármacos con teobromina y su uso en terapia
Inventor: BREW JHON
IPC: A61K31/485
Filed: 2012-05-11
Abstract: Un agente comprende teobromina y un opiato, para el uso simultáneo, secuencial o por separado en terapia. Preferentemente, la terapia es para la tos.
Patent CO-6650363-A2 (CO)
Title: Preparación recubierta con partículas finas
Inventor: NAKAMURA KAZUHIRO
IPC: A61K9/20
Filed: 2013-01-09
Abstract: La presente invención proporciona una preparación que no se siente sustancialmente el estímulo en la cavidad oral y en la faringe y que al mismo tiempo se mantiene excelentes propiedades de elución y desintegración rápida en la cavidad oral aún mediante la conservación en condiciones de alta temperatura y alta humedad, siendo una tableta de desintegración rápida en la cavidad oral con ácido 2- (3-ciano-4-isobutiloxifenil)-4-metil-5-tiazolcarboxílico como ingrediente activo.Tableta de desintegración rápida en la cavidad oral que contiene las partículas que son las partículas nucleares que contienen ácido 2-(3-ciano- 4isobutiloxifenil)-4-metil-5-tiazolcarboxíliCo, recubiertas con la capa que contiene cpo1ímero de ácido metacrílico y sobrecubiertas con la capa que contiene azucares solubles en agua.
Patent CO-7160053-A2 (CO)
Title: Proceso para el tratamiento de hidrocarburos licuados usando compuestos de 3-(amino)propan-1,2-diol
Inventor: LAROCHE CHRISTOPHE
IPC: C10G21/20
Filed: 2014-12-12
Abstract: Un método para tratar hidrocarburos licuados incluyendo gases de ácido para remover los gases de ácido mientras que se minimiza la pérdida de especies de aminas, comprendiendo dicho método el paso de contactar los hidrocarburos licuados con una solución acuosa absorbente de un primer compuesto de amina, teniendo el primer compuesto de amina la estructura (I), en donde Res propan-2,3-diol; Res hidrógeno, metilo, etilo, 2-hidroxietilo, o propan-2,3-diol; y Res hidrógeno, metilo, etilo, 2-hidroxietilo o propan-2,3-diol. 1 2 3
Patent EP-1041709-A2 (EP)
Inventor: THEUS ULRICH DR
IPC: H03B5/06
Filed: 2000-02-19
Abstract: The oscillator circuit has a resonator (RES) and a device (ENT) for amplitude regulation of the oscillation amplitude of the resonator connected across its circuit terminals (K1,K2), providing a variable amplification and/or gradient, which remains cons over the full oscillation period, independent of the momentary voltage and/or current at the circuit terminals.
Patent EP-1063158-A2 (EP)
Inventor: YAMAMOTO YOSHIAKI
IPC: B62J17/02
Filed: 2000-06-26
Abstract: [Object] To provide a front section structure for a vehicle
capable of ensuring that the wind whistle is reduced, the
structure is simplified, the structure for mounting the screen is
not limited, the wind guide is short in length, and the
resistance of passage line is reduced. 
     [Structure] A screen as a windshield screen 33 in the front
section of the vehicle is disposed; an inlet 33b for introducing
a running wind into the back side of the screen 33 and a wind
guide plate portion 33c for guiding the running wind introduced
from the inlet 33b upwardly toward the rear section are formed
at the lower portion 33a of the screen 33.
Patent EP-1079236-A2 (EP)
Inventor: SCHAUWECKER ROBERT
IPC: G01R33/421
Filed: 2000-08-17
Abstract: Radial inner and outer coil systems (M1,M2) have equal current and large dipole moment. A shim coil system corrects magnetic field non-homogeneity in an operating volume with a z component varying proportionally at z<2>. The shim coil system has a radial inner (Si) and outer (Sa) shim coil set each decoupled inductively by a magnetic device and each creating a magnetic field in the operating volume, the inner with a z component varying as  DELTA H0+c2.z2 with c2=const. and the outer with a  DELTA H0 magnetic field.
Patent EP-1083071-A2 (EP)
Inventor: SCHUETT THOMAS
IPC: B60J7/12
Filed: 2000-08-24
Abstract: The roof element is formed as a composite component and has a plastics component (2) and a sheet metal part (3) made of steel or aluminium plate. At least part, and preferably most, of the plastics and sheet metal parts are spaced from each other and form a thin-walled large-volume stiff hollow structure. Then plastics and metal parts may be secured by gluing, welding or clinching. An Independent claim is included for a cabriolet roof incorporating the element.
Patent EP-1081341-A2 (EP)
Inventor: TAKANO TOMOTAKA
IPC: F01L1/053
Filed: 2000-09-04
Abstract: An engine having a valve drive mechanism located at end portions of an intake cam
shaft and an exhaust cam shaft with first and second phase changing devices for
changing the rotational phases of said cam shafts, wherein both cam shaft phase
changing devices are provided on one and the same side of the engine, an input section
of the phase change device on one cam shaft is connected to a crank shaft through first
belt type transmission means and an output section of the phase change device is
connected to said one cam shaft; to said one cam shaft is connected an input section of
the phase change device of the other cam shaft through second belt type transmission
means and to an output section of the phase change device of said other cam shaft is
connected to said other cam shaft; and over a pulley supported on the outside
circumference of the phase change device of said other cam shaft is stretched said first
belt type transmission means, and that a bearing is supported on the first cam shaft
phase change device.
Patent EP-1106561-A2 (EP)
Inventor: BAGNAIA ANTONIO
IPC: B66B17/12
Filed: 2000-12-01
Abstract: An elevator (1) has a car (9) and a lift assembly
(12) for lifting the car (9) and in turn having a motor
reducer (13) housed in a motor compartment (14) of the
elevator (1), a cable transmission (17) activated by the
motor reducer (13), and a counterweight (21) movable
vertically together with the car (9); the counterweight
(21) being portal-shaped and having an opening (25)
extending from a bottom lateral surface (26) of the
counterweight (21) to permit access to the motor
compartment (14) regardless of the vertical position of
the counterweight (21).
Patent EP-1120501-A2 (EP)
Inventor: BOTH DETLEV
IPC: E03F1/00
Filed: 2000-12-22
Abstract: The intermediate container, with its external dimensions established in conformity with the space available for it, is produced of a plastic powder material (preferably polyethylene) with use of a rotation process.
Patent EP-1053924-A2 (EP)
Inventor: HOERNER MICHEL
IPC: B60T13/575
Filed: 2000-04-19
Abstract: A brake booster comprises a housing; a diaphragm sealingly
mounted inside the housing to define separate chambers inside the housing; a
piston (20) having a longitudinal axis (A), the piston being secured to the
diaphragm, extending out of the housing, and being movable along the axis
relative to the housing; a reaction member mounted in the piston; an input
member (22) extending into the piston and engageable with one side (29) of the
reaction member; a disc (32) engageable with the other side (31) of the reaction
member; a Belleville spring (34) mounted on the disc; an annular member (38)
positioned radially outwards of the disc and engageable with the other side of
the reaction member; an output member (24) engaging the Belleville spring, the
Belleville spring biasing the output member away from the reaction disc in the
rest position of the booster such that only the disc acts on the output member
below a predetermined input force (F 1 ) on the input member, and such that at or
above the predetermined input force the bias of the Belleville spring is
overcome and both the disc and the annular member act on the output member.
Provides a ratio change for the booster in a simple manner.
Patent EP-1044878-A2 (EP)
Inventor: FERRY DAVID
IPC: B60N2/90
Filed: 1998-04-02
Abstract: A seating unit (B) for a vehicle, particularly an aircraft, said seating unit
comprising a movable portion comprising a back rest (22), a seat pan (20) and a
leg rest (24), which movable portion is movable between a fully reclined position
and an upright position; characterised by a fixed portion (10) for supporting the
seat adjacent a floor of a vehicle, said fixed portion having front and rear legs (17,
30), each of said front and rear legs having a lower end, and defining a recess (18)
disposed below the back rest and seat pan in the upright position, said recess (18)
being capable of receiving a leg rest (24) of another seat (A); front and rear
cross-members (28, 32) that can be fixedly secured respectively to the lower ends
of the front and rear legs; and fixing means for fixing each of said cross-members
to seat tracks provided in the vehicle.
Patent EP-1039714-A2 (EP)
Inventor: KIM JIN-SOOK
IPC: H04J11/00
Filed: 2000-03-22
Abstract: An orthogonal frequency division multiplexing (OFDM) transmission/receiving system,
and a block encoding method therefor, are provided. The OFDM transmission system
includes a block encoder (100) for encoding binary data of U length into V-ary data
expressed in a group of n bits according to a predetermined mapping rule, a serial-to-parallel
converter (101) for converting the V-ary data into parallel data, a V-ary
modulator (102) for V-ary modulating V-ary data received in parallel to generate an
orthogonal frequency division multiplexing (OFDM) symbol having U sub-symbols, and a
transmitter for transmitting the OFDM symbol. In this method, Q-ary data is block
encoded and Q-ary modulated to reduce the ratio of the peak power to the average power
of an OFDM signal when it is transmitted, so that the OFDM signal can be transmitted at
a high data transmission rate as compared to the prior art in which binary data is block
encoded.
Patent EP-1091297-A2 (EP)
Inventor: FRAZIER RALPH EDWIN
IPC: G06F9/46
Filed: 2000-08-25
Abstract: Disclosed is a Software Sanity Monitor for
automatically detecting and remedying software lock-up
conditions without user intervention. Users often refer
to these conditions as "hangs" or "forever loops".
Although the Software Sanity Monitor uses the operating
software's information, it is designed to execute
independent of the operating system software; thereby,
eliminating reliance on a "sane" operating system. If a
"hang" condition is detected, the Software Sanity Monitor
will automatically restart the system after logging the
failure and, optionally, notify the user or host system.
Patent EP-1111097-A2 (EP)
Inventor: TAMURA TAKAAKI
IPC: C25D3/58
Filed: 2000-10-23
Abstract: A tin/copper alloy electroplating solution capable of
forming a bright plating film in a wide electric current
density range is provided. The electroplating solution is
a cyanide-free aqueous solution containing an
organosulfonic acid, divalent tin and copper salts, as
metal salts, of the organosulfonic acid, a dispersant, and
a brightener.
Patent EP-1076413-A2 (EP)
Inventor: TANIGUCHI NORIO
IPC: H03H9/02
Filed: 2000-08-10
Abstract: A surface acoustic wave filter (10) includes a Y-cut 
X-propagation LiTaO 3  substrate (20) having a cut angle of about 38 degrees to
about 46 degrees, at least first and second series arm surface acoustic wave
resonators (11a,11b) connected in series to define a series arm, and at least one
parallel arm surface acoustic wave resonator (12a-c) connected to the series arm.
Each of the first and second series arm surface acoustic wave resonators (11a,11b)
includes an interdigital transducer having a plurality of pairs of electrode fingers,
and where the number of pairs of electrode fingers of the first series arm surface
acoustic wave resonator (11a) is represented by N (N = natural number), the
corresponding number for the second series arm surface acoustic wave resonator
(11b) differs from n × N (n = natural number).
Patent EP-1144598-A2 (EP)
Inventor: HILLMAN JENNIFER L
IPC: A61P1/18
Filed: 2000-01-14
Abstract: The invention provides human proteins associated with circadian rhythms (CIRYP) and polynucleotides which identify and encode CIRYP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CIRYP.
Patent EP-1171989-A2 (EP)
Inventor: MEDVINSKY SASHA
IPC: G06F1/00
Filed: 2000-04-07
Abstract: A secure Internet Protocol (IP) telephony system, apparatus, and methods are disclosed. Communications over an IP telephony system can be secured by securing communications to and from a Cable Telephony Adapter (CTA). The system can include one or more CTAs, network servers, servers configured as signaling controllers, key distribution centers (KDC), and can include gateways that couple the IP telephony system to a Public Switched Telephone Network (PSTN). Each CTA can be configured as secure hardware and can be configured with multiple encryption keys that are used to communicate signaling or bearer channel communications. The KDC can be configured to periodically distribute symmetric encryption keys to secure communications between devices that have been provisioned to operate in the system and signaling controllers. The secure devices, such as the CTA, can communicate with other secure devices by establishing signaling and bearer channels that are encrypted with session specific symmetric keys derived from a symmetric key distributed by a signaling controller.
Patent EP-1189876-A2 (EP)
Inventor: IONKIN ALEX SERGEY
IPC: C07C/
Filed: 2000-04-25
Abstract: Provided is a selective hydrogenation process for producing aminonitriles by contacting the corresponding dinitriles with a hydrogen-containing fluid in the presence of a hydrogenation catalyst, a solvent and an additive for improving the yield of and/or selectivity to the aminonitrile. The additive comprises a carbon monoxide; a tetraalkylammonium hydroxide compound; a tetraalkylphosphonium hydroxide compound; a multi-centered metal carbonyl cluster; an organic isonitrile; a cyanide compound having at least one cyano group bound to other than a carbon atom; and afluoride compound.
Patent EP-1234478-A2 (EP)
Inventor: BUOS ANDREAS
IPC: H04R1/28
Filed: 2000-11-28
Abstract: La présente invention concerne un haut-parleur se présentant sous forme de panneau à onde de flexion. Ce haut-parleur comprend une paire espacée de panneaux, qui définissent entre eux une cavité de fluide peu profonde, un élément de corps, qui entoure ladite paire de panneaux et suspend lesdits panneaux par leurs bords, ainsi que des moyens, qui permettent de sceller la cavité et des transducteurs de vibrations dans la cavité de fluide et sont conçus pour commander les panneaux respectifs. Selon cette invention, les connexions électriques aux transducteurs sont au moins partiellement en opposition de phase, de façon que le mouvement principal des panneaux est en phase, afin d'assurer un degré de propriété de rayonnement de dipôle pour le haut-parleur, et la cavité est telle, que l'espacement entre les panneaux s'élève de 2 à 25 mm, de façon que la cavité peu profonde fournit des conditions dans lesquelles la dynamique et le comportement de connexion fluidique sont affirmés entre la paire de panneaux, en raison de la couche de fluide qui se trouve entre eux.
Patent EP-1122687-A2 (EP)
Inventor: IBEKE RYOHJI
IPC: G10L13/04
Filed: 2001-01-25
Abstract: The emotion expressing device comprises an
emotion creating device (200) which decides an emotion,
a sound creating device for creating a sound for
representing the emotion, an emotional interactive
statement creating device (400) which creates words for
representing the emotion, a movement creating device
(500) which creates a movement for representing the
emotion, an expression creating device (600) which
creates an expression for representing the emotion, and
an expression information integrating device (800) which
performs the layout processing and the output
synchronization processing in output of the created
sound, words, movement, and expression.