baber/WOPTO huggingface dataset:
Patent DE-69001899-T2 (DE)
Inventor: ANDERSEN ANDERS
IPC: C07K7/06
Filed: 1990-03-14
Granted: 1993-09-23
Abstract: Pentapeptides having the formula H-Asp-Ser-C-Pro-Arg-OH, where Asp, Ser, Pro and Arg may have L- or D-configuration, and C denotes Asp or Asn in L or D configuration, are synthesized by reacting in an aqueous medium Y2-Pro-OH, wherein Y2 is a protective group, with Arg-Ro, wherein Ro is OH or is as defined below for R1 below, to form Y2-Pro-Arg-Ro, which is deprotected, if necessary under conversion to Pro-Arg-R1, wherein R1 is an enzymatically cleavable  alpha -carboxy substituting group selected from esters, amides, anilides, hydrazides or L-amino acid esters, and thereafter reacting Y3-C(Z3)-OH with Pro-Arg-R1 to form Y3-C(Z3)-Pro-Arg-R1, which is deprotected to C-Pro-Arg-R1, and then reacting Y4-Ser-OH with C-Pro-Arg-R1 to form Y4-Ser-C-Pro-Arg-R1, which is deprotected to Ser-C-Pro-Arg-R1, and reacting Y5-Asp(Z5)-OH with Ser-C-Pro-Arg-R1 to form Y5-Asp(Z5)-Ser-C-Pro-Arg-R1, which is deprotected to the intermediate Asp-Ser-C-Pro-Arg-R1, and finally removing the group R1 with an enzyme, preferably trypsin to form Asp-Ser-C-Pro-Arg, or removing R1 from Y5-Asp(Z5)-Ser-C-Pro-Arg-R1 before deprotection to Asp-Ser-C-Pro-Arg-OH. The groups Y2, Y3, Y4, Y5, Z3 and Z5 are protective groups which apart from Y2 are removable by catalytic hydrogenation. The employed synthesis strategy based on the combination hydrogenation/enzyme, both proceeding under mild conditions, leads to the peptides, in particular HEPP, in good yield without risk of formation of  beta -aspartyl peptides and cleavage of Asp-Pro bonds.
Patent DE-69004305-T2 (DE)
Inventor: HUNG WILLIAM M
IPC: G02C13/00
Filed: 1990-03-07
Granted: 1994-03-24
Abstract: An improvement in a process for preparing a contact lens tinted over at least a portion of its surface, having the steps of forming a tinting solution having a reactive dyestuff and applying the tinting solution to a polymeric hydrogel contact lens material, wherein the improvement comprises adding an effective amount of an ammonium quaternary salt to the tinting solution before the applying step.
Patent DE-69013502-T2 (DE)
Inventor: MARKSTROEM ESKIL
IPC: E02F5/00
Filed: 1990-02-14
Granted: 1995-05-18
Abstract: PCT No. PCT/SE90/00096 Sec. 371 Date Aug. 14, 1991 Sec. 102(e) Date Aug. 14, 1991 PCT Filed Feb. 14, 1990 PCT Pub. No. WO90/09489 PCT Pub. Date Aug. 23, 1990.A track-mounted excavating machine comprises a chassis having ground-support tracks, and a cabin mounted on the chassis. A first tool is carried by the cabin, and a second tool is carried by the chassis. The second tool can be (a) extended and retracted toward and away from the chassis, (b) raised and lowered relative to the chassis, and (c) rotated about a vertical axis relative to the chassis. The second tool comprises claws having toothed sides mounted thereon for slidable adjustment toward and away from outer ends of the claws.
Patent DE-69017562-T2 (DE)
Inventor: SAWADA TAKASHI
IPC: G01N33/543
Filed: 1990-08-30
Granted: 1995-08-24
Abstract: The assay method comprises the steps of adding a serum specimen to a solid phase at a pH value of 9 to 10 and assaying an antibody in the specimen. The antibody may be adult T cell leukemia virus antibody (HTLV-I antibody).
Patent DE-69024730-T2 (DE)
Inventor: NEAL JOSEPH H
IPC: G11C7/10
Filed: 1990-08-27
Granted: 1996-08-14
Abstract: A semiconductor memory device architecture by which a given number of discrete components can provide a memory module of increased capacity. A memory module (50) includes a plurality of discrete memory circuits (52) each organized to provide an individual data string having a length that is an integer multiple of four bits. The memory circuits (52) are arranged to provide a combined data string having a length equal to the sum of the individual data string lengths and each circuit includes a signal line connected to control transfer of individual data strings. A different data pin is associated with each bit of the combined data string to transfer a datum for output from the module. Each signal line is connected to a control pin to receive an external signal for initiating transfer of one of the individual strings from one memory circuits (52). The module (50) comprises an additional memory circuit (10) which includes a plurality of additional signal lines and a plurality of additional data lines. A first of the additional signal lines is wired in common with the signal line of a first one of the data memory circuits and a second of the additional signal lines is wired in common with the signal line of a second one of the data memory circuits. The additional circuit is responsive to transfer a bit of data along one of the additional data lines when an individual data string is transferred from one of the memory circuits.
Patent DE-69027991-T2 (DE)
Inventor: KOHN ELSIE
IPC: C07D249/04
Filed: 1990-05-18
Granted: 1997-02-06
Abstract: Tumor invasion and metastasis is the most life threatening aspect of cancer. Invasion and metastasis is a multistep process. Cellular functions required for invasion are attachment, locomotion and directed migration. Regulation of these processes may be independent of cell growth. A carboxylamino-imidazole compound was found to be potent inhibitor of tumor cell attachment, motility, invasion, proliferation, and metastasis. This compound and equivalents thereof constitute a cancer treatment agent of particular use in the treatment of peritoneal carcinomatosis of ovarian cancer.
Patent DE-69032708-T2 (DE)
Inventor: THIRUMALAI AJAI
IPC: G06F15/17
Filed: 1990-07-20
Granted: 1999-04-29
Abstract: A process for transferring information including a source or destination address between two nodes in a network via data switching logic. The switching logic must decode commands and addresses in order to adopt the proper configuration so that the commands and addresses can be forwarded from one system resource to another system resource. A read or write address is transmitted to the switching logic and decoded in order to configure the switching logic. The same read or write address is then retransmitted to the switching logic for forwarding to the appropriate system resource. As a result, there is no need for extra storage logic in order to retain read and write addresses while the switching logic is being configured.
Patent DE-69033089-T2 (DE)
Inventor: DANDL RAPHAEL
IPC: H01L21/302
Filed: 1990-03-08
Granted: 1999-12-16
Abstract: A method and apparatus are disclosed employing electron cyclotron resonant (ECR) heating to produce plasma for applications including but not limited to chemical vapor deposition and etching. A magnetic field is formed by magnets circumferentially arranged about a cylindrical and symmetrical chamber with microwave power injected perpendicularly to a longitudinal axis of the chamber for preventing line-of-sight communication of resulting energetic electrons through an outlet at one axial end of the chamber. The circumferential magnets in the symmetrical chamber cause precessing of the electrons resulting in greatly increased plasma density and ion flux or current density even at low gas pressures which are preferably maintained for establishing unidirectionality or anisotropic plasma characteristics. A magnetic field free region is formed between the plasma forming region containing the microwave power source and the circumferential magnets in order to also produce uniformity of plasma distribution in a plasma stream approaching the outlet. Thus, with specimens aranged in communication with the outlet, the above characteristics are maintained for the plasma stream over substantial transverse dimensions larger than the specimen.
Patent DE-69033875-T2 (DE)
Inventor: MUENTER ADAMS
IPC: G03C7/30
Filed: 1990-10-17
Granted: 2002-04-25
Abstract: There is described a process for recording a positive or negative continuous tone color copy having the same or lower contrast than a continuous tone original image, comprising the steps of: providing a photographic element comprising a support having thereon a silver halide emulsion unit capable of forming a yellow image, a silver halide emulsion unit capable of formign a cyan image, and a silver halide emulsion unit capable of forming a magnenta image, each image-forming unit having a maximum spectral sensitivity at a different wavelength of radiation, and at least one of the image-forming units having a gamma as described herein, receiving image data representing the densities of the yellow, magenta, and cyan records of the original image, modifying said image data and using it to control three exposure sources, each emitting radiation in the region of maximum spectral sensitivity for a corresponding one of the image-forming units, so that, after exposure, the recorded image density range for at least one of the yellow, magenta, and cyan image-forming units is substantially the same as or lower than the image density range for the corresponding yellow, magenta, and cyan records, respectively, of said original image, and exposing said photographic element to said exposure sources.
Patent DE-69105531-T2 (DE)
Inventor: WILSON JAMES BRETT STEPHEN
IPC: E01F15/12
Filed: 1991-01-15
Granted: 1995-06-08
Abstract: A removable barrier (1) adapted to co-operate with a concrete median barrier (2) of a roadway to form, in situ, a barrier between a vehicle travelling in one direction on the roadway and a vehicle travelling in another direction, wherein:   the removable barrier is adapted for movement such that, when desirable, the vehicle travelling in the one direction can transgress the barrier and travel on the opposite side of the roadway, and further wherein the removable barrier comprises at least one shell conforming substantially to the outer shape of the concrete median barrier and is adapted for sliding movement relative to the concrete median barrier.   <IMAGE>
Patent DE-69115313-T2 (DE)
Inventor: JUNG FREDERICK HENRI
IPC: A61P31/04
Filed: 1991-03-07
Granted: 1996-05-02
Abstract: A compound of the formula (II): <CHEM> and pharmaceutically acceptable salts and in vivo hydrolysable esters are described as is their preparation and use as antibacterial agents.
Patent DE-69115431-T2 (DE)
Inventor: GROSS JOSEPH
IPC: B05B11/00
Filed: 1991-09-13
Granted: 1996-05-02
Abstract: A liquid material dispenser includes a rigid housing (2) having a flexible partition defining first and second compartments (4, 6) on opposite sides of the partition, and an electrolytic cell (22) in the first compartment (4) capable of generating a gas when energized by a source of electric current in order to expand the first compartment (4) and thereby to contract the second compartment (6). The second compartment (6) contains the liquid material which is dispensed via a discharge opening (8) in accordance with the rate of generation of the gas. <IMAGE>   <IMAGE>
Patent DE-69117183-T2 (DE)
Inventor: SIPOS BALAZS
IPC: A43B17/14
Filed: 1991-07-02
Granted: 1996-06-27
Abstract: The therapeutical auxiliary means, preferably instep raiser according to the invention for treating and/or healing deformations of the arch of the foot is provided with exchangeable, differently shaped pressing profiles (3, 4, 5, 6, 7, 8, 9, 10, 11, 12) made of diverse materials being suitable for treating and healing deformation of the arch of the foot, as well as with a perforated base plate (2) made of some flexible, tough material. Further, the base plate (2) and the pressing profiles (3 to 12) are covered with an enveloping multi-layer coating (13).
Patent DE-69120452-T2 (DE)
Inventor: BEGGS THOMAS STEWART
IPC: C12N9/08
Filed: 1991-03-20
Granted: 1996-10-31
Abstract: One or more vehicles, which may be acceptable to enter the mouth, contain at least one of two cooperating enzymes plus an antibody or antibody fragment which binds to a target site. There are means to attach both enzymes to such antibodies or fragments thereof, so as to bind the enzymes to the vicinity of the target. One enzyme generates an intermediate which is used by the other enzyme to generate a substance, preferably hypohalite, which acts at the target site. <IMAGE>
Patent DE-69131256-T2 (DE)
Inventor: DAUBENMIER JOHN A
IPC: F16H61/04
Filed: 1991-08-15
Granted: 1999-09-23
Abstract: A control system for an automatic transmission for an automotive vehicle having a torque converter and a combustion engine including a microprocessor that is adapted to establish optimum control pressure levels for fluid pressure operated clutch and brake servos that effect gear ratio changes wherein provision is made for adjusting system pressures to maintain ratio shift quality in accordance with variations in a plurality of control sensor inputs including vehicle deceleration during ratio shifting and changes in the rate of change of converter turbine speed wherein optimum servo pressures are maintained following a ratio shift and during a ratio shift as torque capacity of one servo is reduced in synchronism with a torque capacity increase for a companion servo. <IMAGE>
Patent DE-69132031-T2 (DE)
Inventor: WEICHSELBAUM R
IPC: A61K41/00
Filed: 1991-12-19
Granted: 2000-07-13
Abstract: This invention relates to genetic constructs which comprise an enhancer-promoter region which is responsive to radiation, and at least one structural gene whose expression is controlled by the enhancer-promoter. This invention also relates to methods of destroying, altering, or inactivating cells in target tissue by delivering the genetic constructs to the cells of the tissues and inducing expression of the structural gene or genes in the construct by exposing the tissues to ionizing radiation. This invention is useful for treating patients with cancer, clotting disorders, myocardial infarction, and other diseases for which target tissues can be identified and for which gene expression of the construct within the target tissues can alleviate the disease or disorder.
Patent DE-69207990-T2 (DE)
Inventor: DELWEL FRANCOIS
IPC: B01J2/04
Filed: 1992-06-25
Granted: 1996-05-30
Abstract: Alkali metal silicate solutions are formed into granules in a single stage. The heated solution is sprayed into a heated drum having a multiplicity of arms fixed to a rapid by rotating central shaft. A gas, preferably air, heated to 150  DEG C to 200  DEG C is also introduced with the silicate solution and a granulated product is obtained from the other end of the drum.
Patent DE-69208295-T2 (DE)
Inventor: MILTON RICHARD O
IPC: E01F9/627
Filed: 1992-01-15
Granted: 1996-11-14
Abstract: An impact recovery delineation system comprises a base member that provides improved mechanical and chemical bonding to the road surface and a portable base that provides a rigid center portion and flexible ends to maintain the position of the delineator device after vehicle impact. A sealed, pneumatic tube of high impact resistant material composition acts as a delineator post and is adapted to receive modified load cells. Upper and lower load cell elements are provided with cable passages to allow side-by-side placement of wire rope cables. The passages are particularly geometrically configured and have two radiused edges and two straight edges which result in rapid bending and recovery of the delineator post system upon high speed impact, in any direction, by an automotive vehicle. A vented signage panel having air vents therein to reduce wind resistance, improve and speed recovery of the impacted system. A safety loop in the cable system is provided to prevent the delineator post and signage from being separated from the load cell abutment base connection should there be a structural failure at this connection. A flexible portable base structure is provided for temporary location of delineation posts and which is provided with an intermediate stiffener and flexible weighted ends to prevent its lifting from the roadway upon vehicle impact with the impact recovery delineator post system supported thereby.
Patent DE-69217983-T2 (DE)
Inventor: NAGEL CHRISTOPHER
IPC: C22B60/02
Filed: 1992-11-06
Granted: 1997-10-09
Abstract: A method is disclosed for producing a non-radioactive product from a radioactive waste composition that includes a radioactive component and a non-radioactive component. The method includes directing the radioactive waste into a molten metal bath. A separation agent is directed in the molten metal bath which reacts with a component of the radioactive waste composition to form a reaction product which separates from the remaining component, thereby forming a non-radioactive product. The separation reagent can be, for example, an oxidant, a metal-ligand exchange reagent, or a reducing agent. The non-radioactive product can be a gas, a liquid, or a precipitate.
Patent DE-69223605-T2 (DE)
Inventor: GRAVES PAUL
IPC: C04B28/02
Filed: 1992-09-10
Granted: 1998-07-02
Abstract: There is provided a method for the ecologically safe disposal of lead-contaminated hazardous industrial wastes (such, as for example, those generated as discardable by-products in primary and secondary lead smelting operations, especially, blast furnace slags and matte), which comprises reducing the size of the lead-contaminated industrial wastes and treating them, prior to encapsulation in a hardenable material, with the naturally occuring zeolite, clinoptilolite, in an amount sufficient to prevent lead ions (Pb<+2>) from leaching out of such industrial wastes, through exposure to the action of atmospheric agents (e.g., hot air and rain, or as a result of cyclical freezing and thawing in temperature climates), even over an extended period of time.
Patent DE-69232923-T2 (DE)
Inventor: CHEN TEH-KUEI
IPC: C07D241/12
Filed: 1992-03-17
Granted: 2003-08-21
Abstract: A process for the preparation of an alkyl pyrazine which comprises refluxing or refluxing with simultaneous sublimation of a mixture of an acyloin having the general formula: <CHEM> wherein R1 and R2 are either both methyl radicals or R1 is hydrogen and R2 is a saturated or unsaturated alkyl radical containing from 1 to 10 carbon atoms and an ammonium salt in water and isolating the product. <IMAGE>
Patent DE-69300014-T2 (DE)
Inventor: SCARDOVI ITALO
IPC: B30B15/02
Filed: 1993-02-03
Granted: 1995-02-23
Abstract: The invention relates to a die for ceramic tiles. The die comprises two semi-dies (1) and (2), between which the material to be compacted is pressed, one of which half-dies (1) or (2) exhibits an elastic wall (4), on which elastic wall (4) external face the imprint of one of the faces of the tile (6) to be realised is inscribed; the said elastic wall (4) is positioned over and in contact with a cavity (5) filled with an incompressable liquid, which cavity is divided into portions by a lattice (7). <IMAGE>
Patent DE-69301180-T2 (DE)
Inventor: HAMELERS BERTUS VICTOR MARIE
IPC: C05F9/00
Filed: 1993-04-15
Granted: 1996-09-12
Abstract: Method for processing vegetable, fruit and garden waste, indicated as VFG-waste, in which, after a pre-sorting has taken place, the waste (3) is brought into a washing-separating device (4), in which, with the help of water, the waste is separated into a coarse organic fraction (6) which is composted and into a residual fraction (7). The coarse fraction contains particles larger than 2 up to 4 mm. The residual fraction (7) is separated into an inert fraction (11) for recovering sand (13) therefrom, and into a fraction (15) consisting of liquid containing a fine organic fraction (17) and substances dissolved and colloidally divided in the liquid. The fraction (15), obtained from the residual fraction (7) after removing the inert fraction (11) therefrom, is subjected to an anaerobic stabilization. <IMAGE>
Patent DE-69324292-T2 (DE)
Inventor: PALLEGGI GUIDO
IPC: B60L50/15
Filed: 1993-02-17
Granted: 1999-08-26
Abstract: An electric drive system in lift trucks has, for driving the lift truck driving wheels, at least one separate excitation electric motor (M) provided with a stator (C) and a rotor (A) which are energized independently of each other by means of an electronic drive and control unit; by this arrangement, space can be saved on the lift truck and the lift truck can be rendered reliable, low in running cost, adaptable to varying load conditions, and adjustable as regards its operational parameters. <IMAGE>
Patent DE-69328023-T2 (DE)
Inventor: LEBOEUF R
IPC: C08J/
Filed: 1993-04-30
Granted: 2000-07-13
Abstract: The tackiness associated with certain soft acrylic polymers can be reduced by plasma treatment of the polymer surface. This is particularly useful with regard to intraocular lenses (IOLs), especially foldable IOLs, which are made from such soft acrylic polymers.
Patent DE-69331149-T2 (DE)
Inventor: VAN DEN WIJDEVEN GIJSBERDUS GE
IPC: A61M37/00
Filed: 1993-05-13
Granted: 2002-06-20
Abstract: PCT No. PCT/NL93/00098 Sec. 371 Date Jan. 9, 1995 Sec. 102(e) Date Jan. 9, 1995 PCT Filed May 13, 1993 PCT Pub. No. WO93/23110 PCT Pub. Date Nov. 25, 1993The present invention relates to a method and a device for injecting humans and animals with a pharmaceutical preparation, wherein the preparation is held in a rigid carrier (5) and the carrier is carried through the skin into the body by means of gas pressure, and wherein during carrying of a rigid carrier (5) into the body by means of gas pressure the device with which the carrier is carried into the body is held against the body. The invention likewise relates to a device for injecting animals or humans with a pharmaceutical preparation, wherein a chamber (2) is present in which a carrier (5) containing the pharmaceutical preparation can be placed, a barrel (1) connecting onto this chamber and means for carrying the carrier by means of gas pressure through the barrel into the body for injecting, wherein means are present for blocking the use of the device when it is not pressed against a body.
Patent DE-69400196-T2 (DE)
Inventor: MACAUDIERE PIERRE
IPC: A61Q1/02
Filed: 1994-06-06
Granted: 1996-12-05
Abstract: The invention relates to a process for the treatment of pigments based on rare-earth sesquisulphides, aimed more particularly at improving the colour of the latter, the said process being characterised in that it consists in subjecting the said pigments to a fluoridation treatment allowing fluorine atoms to be incorporated, preferably at the surface, within the said pigments. The invention also relates to new pigments based on rare-earth sesquisulphides with improved chromatic properties and characterised essentially in that they contain fluorine atoms, preferably at the surface. These fluoridised pigments may furthermore take an encapsulated form, preferably in silica. The invention finally relates to the use of the said pigments for colouring various materials, in particular plastics.
Patent DE-69400389-T2 (DE)
Inventor: ESCUDERO JOSE
IPC: H03K17/73
Filed: 1994-05-27
Granted: 1997-03-27
Abstract: The MOSFETs or IGBTs of respective arms of an electronic inverter are in series with SCRs or TRIACs triggered into conduction during intervals of intended conduction of the respective MOSFETs or IGBTs connected to the high level rectifier terminal. The piloting of the SCRs or TRIACs is effected from the piloting of the MOSFETs or with delay or in a conditional manner. The circuit eliminates the effective transience on the inverter output.