baber/WOPTO huggingface dataset:
Patent AU-782298-B2 (AU)
Title: Polymer stabilized neuropeptides
Inventor: BENTLEY MICHAEL DAVID
IPC: A61K47/48
Filed: 2000-10-04
Granted: 2005-07-14
Abstract: A substantially hydrophilic conjugate is provided having a peptide that is capable of passing the blood-brain barrier covalently linked to a water-soluble nonpeptidic polymer such as polyethylene glycol. The conjugate exhibits improved solubility and in vivo stability and is capable of passing the blood-brain barrier of an animal.
Patent AU-730399-B2 (AU)
Title: Peritoneal dialysis tube connection with dual disinfectant system
Inventor: LOH ERIC P
IPC: A61M39/18
Filed: 1997-03-13
Granted: 2001-03-08
Abstract: A connector assembly and disinfectant system is provided for any system requiring a connection, such as during a peritoneal dialysis procedure. The connector assembly includes a transfer set connector and a disposable connector. The transfer set connector and disposable connector each include a member that join to create a fluid path. The disposable connector contains a housing that includes a ring partially saturated with disinfectant for bathing the transfer set member near the opening of the fluid path when a connection is made. The ring forms an opening through which the transfer set member passes. At disconnection, the transfer set member passes through a section of the ring having wiping properties to wipe the member dry.
Patent AU-610258-B2 (AU)
Title: A device for extracorporeal treatment of diseased body fluid
Inventor: HONARD MARK R
IPC: A61M1/10
Filed: 1988-10-10
Granted: 1991-05-16
Abstract: A therapeutic device for removing pathological effectors from body fluids of a patient is disclosed. Said device includes a chamber for receiving the body fluids and positioned within the chamber is a biospecific polymer. Said biospecific polymer interacts with and binds specific pathological effectors carried by the body fluid that is passed through the chamber.
Patent AU-783992-B2 (AU)
Title: Method of using a cyclooxygenase-2 inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
Inventor: MCKEARN JOHN P
IPC: A61K33/243
Filed: 1999-12-22
Granted: 2006-01-12
Abstract: The present invention provides methods to treat neoplasia disorders in a mammal using a combination of radiation and an integrin antagonist.
Patent AU-568328-B2 (AU)
Title: An apparatus for automatic preparation of food products such as bread, cakes and the like
Inventor: HEDENBERG GUNNAR
IPC: A21B1/22
Filed: 1983-12-27
Granted: 1987-12-24
Abstract: The preparation starts from dry and/or wet ingredients. The apparatus comprises at least one mixing - kneading - and heat treatment station (13, 14). The object of the invention is to provide a baking apparatus by means of which food products such as bread can be produced without any real manual work involved, without soiling vessels and utensils and which can be programmed so that a correct fermentation process under the right temperature conditions is provided. This has been achieved by the fact that in the mixing- and kneading station (13) there are arranged means (11) for holding and/or displacing at least one flexible vessel (12). e.g. a plastic bag, which contains or is intended to receive said ingredients, and that the mixing- and kneading means (87, 88) of the first station are arranged to mix the ingredients and work the mass located in the vessel (12) by outer mechanic agitation of the vessel.
Patent AU-730592-B2 (AU)
Title: Phosphate derivatives of diaryl 1,3,4-oxadiazolone
Inventor: STARRETT JOHN E JR
IPC: A61K31/675
Filed: 1999-01-26
Granted: 2001-03-08
Abstract: The present invention provides novel phosphate derivatives having the general formula wherein A, R1 and R2 are as defined herein, or a nontoxic pharmaceutically acceptable salt or solvate thereof and are useful in the treatment of disorders which are responsive to the opening of potassium channels.
Patent AU-743212-B2 (AU)
Title: Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
Inventor: PAUL PREM S
IPC: C12N15/09
Filed: 1999-02-08
Granted: 2002-01-24
Abstract: The present invention provides a purified preparation containing, for example, at least one polypeptide selected from the group consisting of proteins encoded by one or more open reading frames (ORF's) of an Iowa strain of porcine reproductive and respiratory syndrome virus (PRRSV), antigenic regions of such proteins which are at least 5 amino acids in length and which effectively protect a porcine host against a subsequent challenge with a PRRSV isolate, and combinations thereof in which amino acids non-essential for antigenicity may be conservatively substituted. The present invention also concerns a vaccine comprising an effective amount of such a protein; antibodies which specifically bind to such a protein; methods of producing the same; and methods of protecting a pig against a PRRSV, treating a pig infected by a PRRSV, and detecting PRRSV in a pig.
Patent AU-655506-B2 (AU)
Title: Process for fixing lead-contaminated ecologically hazardous industrial waste materials using clinoptilolite zeolite
Inventor: GRAVES PAUL RAYMOND JR
IPC: B09B3/00
Filed: 1992-09-10
Granted: 1994-12-22
Abstract: There is provided a method for the ecologically safe disposal of lead-contaminated hazardous industrial wastes (such, as for example, those generated as discardable by-products in primary and secondary lead smelting operations, especially, blast furnace slags and matte), which comprises reducing the size of the lead-contaminated industrial wastes and treating them, prior to encapsulation in a hardenable material, with the naturally occuring zeolite, clinoptilolite, in an amount sufficient to prevent lead ions (Pb<+2>) from leaching out of such industrial wastes, through exposure to the action of atmospheric agents (e.g., hot air and rain, or as a result of cyclical freezing and thawing in temperature climates), even over an extended period of time.
Patent AU-709795-B2 (AU)
Title: Method of inducing an immune response with a live venezuelan equine encephalitis virus expressing a heterologous immunogen
Inventor: JOHNSTON ROBERT E
IPC: C07K14/285
Filed: 1995-05-26
Granted: 1999-09-09
Abstract: Novel attenuating mutations of Venezuelan Equine Encephalitis (VEE) are disclosed. Further aspects of the invention include an infectious VEE virus transcript encoded by cDNA clones, infectious VEE virus particles, and pharmaceutical formulations containing such infectious particles. Also disclosed are recombinant VEE virus containing a heterologous RNA segment.
Patent AU-653073-B2 (AU)
Title: Process for reactivation of water-soluble hydroformylation catalysts
Inventor: KINKOL WERNER
IPC: B01J38/48
Filed: 1992-10-23
Granted: 1994-09-15
Abstract: To restore their effectiveness, deactivated, water-soluble hydroformylation catalysts containing rhodium and sulphonated or carboxylated arylphosphines, are admixed with maleic acid, fumaric acid or olefinically unsaturated compounds of the general formula <IMAGE> in which X represents O, S, N-R<5> or P-R<5> and R<3>, R<4> and R<5> are identical or different and mean hydrogen, an alkyl radical or an aryl radical.
Patent AU-691931-B2 (AU)
Title: Linear alpha-olefin-containing fluid bore-hole treatment agents, in particular corresponding bore-hole flushing agents
Inventor: MULLER HEINZ
IPC: C09K8/26
Filed: 1995-06-06
Granted: 1998-05-28
Abstract: PCT No. PCT/EP95/02143 Sec. 371 Date Dec. 13, 1996 Sec. 102(e) Date Dec. 13, 1996 PCT Filed Jun. 6, 1995 PCT Pub. No. WO95/34610 PCT Pub. Date Dec. 21, 1995The invention relates to the use of at least predominantly linear hydrocarbon compounds olefinically unsaturated in the alpha-position with flashpoints of at least about 80 DEG  as the oil phase or as part of the oil phase of oil- or water-based free-flowing borehole servicing preparations. Particular significance is attributed to corresponding drilling fluids which, together with the alpha-olefins, contain other oil phases from the field of borehole servicing preparations and are distinguished by ecological compatibility, being degradable under both aerobic and anaerobic conditions. Suitable mixture components for the oil phase are, in particular, oleophilic alcohols, ethers and corresponding esters selected from carboxylic acid esters and/or carbonic acid esters.
Patent AU-604394-B2 (AU)
Title: Process for the synthesis of polyol fatty acid polyesters
Inventor: GRECHKE YULIR MESZAROS
IPC: C07H13/06
Filed: 1989-01-03
Granted: 1990-12-13
Abstract: The invention pertains to a process for the synthesis of polyol fatty acid polyesters involving transesterification of a reaction mixture comprising a soap emulsifier in which during the reaction at a degree of conversion within the range of from 15 to 60 % the soap level is substantially reduced. By this process the high-viscosity and separating-out problems attached to the soap emulsifier in the later stages of the reaction are avoided.
Patent AU-648217-B2 (AU)
Title: Tetrahydrothiophene derivatives
Inventor: MITA SHIRO
IPC: C07D333/38
Filed: 1993-02-26
Granted: 1994-04-14
Abstract: A compound of the formula [I] and pharmaceutically acceptable salts thereof; and a synthetic intermediate represented by the fomula [II] and pharmaceutically acceptable salts thereof, <CHEM>   <CHEM>  wherein     R 1 is hydrogen or lower alkyl;     R 2 is hydrogen or a protective group of thiol; R 3 is hydroxy, a remainder of ester group or a remainder of amido group;     A is straight or branched lower alkylene, and the sulfur atom in the side chain may be directly join with -CO- to conform a thiolactone ring. The compounds of this invention have excellent thymulin-like activities and are expected to be useful for treatment of various immune disorders such as immunodeficiency and autoimmune diseases.
Patent AU-652687-B2 (AU)
Title: Griller
Inventor: O'BRIEN WILLIAM JOHN
IPC: H05B3/72
Filed: 1993-03-09
Granted: 1994-09-01
Abstract: A griller having a substantially horizontally extending grill member (10) to support food while being grilled, the grill member (10) consisting of alternating bars (11) and slots (12) the bars (11) being made of aluminium, aluminium alloy or a substance having similar heat transmitting properties there being arranged under the grill member (10) an elongated electric heating element that is accommodated within a groove (17) formed on the underside of the grill member (10), whereby fats and liquids emerging from food being cooked on the grill member (10) are prevented from coming into contact with the electric heating element, electric plug (20) receiving means connected to said electric heating element directly and without intervention of a thermostat, the heating element and the grill member (10) being constructed and arranged so that heat from the heating element is distributed more or less evenly over the surface of the grill member, the grill member (10) being removeably supported on a container (23) that in use underlies the grill member (10) and acts to catch fat and liquids from the food being grilled, there being a circumferential gap (29) between an outer wall of said container (23) and the periphery of the grill member (10) the width of said gap (29) being such as to permit a flow of air into the space beneath the grill member to control the temperature of the heating element and grill member and prevent thermal run away. <IMAGE>
Patent AU-661561-B2 (AU)
Title: Biological artificial liver
Inventor: BARKER GEORGE EDWARD
IPC: C12M3/00
Filed: 1993-01-06
Granted: 1995-07-27
Abstract: Disclosed is a hepatocyte bioreactor or bio-artifical liver which comprises a containment vessel having a perfusion inlet means and a perfusion outlet means; a matrix within said containment vessel so as to entrap hepatocyte aggregates within said containment vessel while allowing perfusion of said matrix. The invention is useful as an artificial liver.
Patent AU-677949-B2 (AU)
Title: Peptide linkage unit comprising methylene phosphinic acid
Inventor: JANDA KIM D
IPC: B60W40/09
Filed: 1993-01-11
Granted: 1997-05-15
Abstract: PCT No. PCT/US93/00228 Sec. 371 Date Jun. 30, 1994 Sec. 102(e) Date Jun. 30, 1994 PCT Filed Jan. 11, 1993 PCT Pub. No. WO93/00228 PCT Pub. Date Jan. 11, 1993A peptide linkage unit is employed for joining peptide and pseudopeptide sequences, including peptides and pseudopeptides that inhibit aspartic proteinase enzymes. The peptide linkage unit includes a phosphinate methylene ammonium linkage in place of a peptidyl carboxamide bond. If the peptide linkage unit is incorporated into a peptide sequence that would otherwise serve as an aspartic proteinase substrate and if it is positioned at a cleavage site within such peptide sequence, the phosphinate methylene ammonium linkage is resistant to cleavage and serves as an exploding transition state analog of such cleavage site. When so incorporated, the phosphinate methylene ammonium linkage can bind or interfere with the active site of aspartic proteinase enzymes and inhibit its activity. Preferred inhibitors contain a phosphinic acid methylene amine group joining the P1 and P1' residues and have a length of 3 to about 15 amino acid residues.
Patent AU-615077-B2 (AU)
Title: Process for direct shaping and optimisation of the mechanical characteristics of penetrating projectiles of high-density tungsten alloys
Inventor: NICOLAS JEAN-CLAUDE
IPC: F42B12/74
Filed: 1989-06-21
Granted: 1991-09-19
Abstract: This invention relates to a process for directly forming and for optimising the mechanical characteristics of armour-piercing projectiles. 
<??>This process involves using a blank of ductile heavy metal having an axis of revolution and mass per unit volume at least equal to 17000 kg/m<3> and is characterised in that the said roughly prepared blank is subjected to a finishing treatment at a temperature between ambient temperature and 500 DEG C and at a rate variable in a direction parallel to the axis of the blank. 
<??>This process is used in military munitions. 
<IMAGE>
Patent AU-617191-B2 (AU)
Title: A travelling on-track machine arrangement for placing and removing sleepers
Inventor: THEURER JOSEF
IPC: E01B29/06
Filed: 1989-06-28
Granted: 1991-11-21
Abstract: A mobile machine arrangement for exchanging old track ties for new track ties comprises first and second machine units, a drive for propelling each machine unit independently along the track in an operating direction, an operator's cab for each machine unit, each machine unit comprising a bridge-like machine frame, a tie loading car coupled to the machine frame and undercarriages supporting the machine frame and the tie loading car on the track, a respective tie exchange device for laterally pulling old ties out of the track mounted on the machine frame of the leading machine unit and for laterally inserting new ties into the track mounted on the machine frame of the trailing machine unit, each tie exchange device comprising power-driven vertically and longitudinally adjustable tie gripping devices, a control for the tie exchange device mounted on each machine unit, and a tie transport arrangement mounted on the machine frame and tie loading car of each machine unit.
Patent AU-776840-B2 (AU)
Title: Prediction of diabetes impaired wound healing by urinary nitrate assay
Inventor: BOYKIN JOSEPH V JR
IPC: A61P3/10
Filed: 2000-03-17
Granted: 2004-09-23
Abstract: Wound healing is impaired in many diabetics, who suffer increased risk of chronic foot ulceration and amputation. Diabetic patients with poor healing ability were found to possess significantly lower fasting urinary nitrate levels than diabetic patients with normal healing ability or non-diabetic controls, implicating decreased endogenous nitric oxide activity as the mediator of diabetes-impaired wound healing. Methods and kits are provided for predicting the wound healing ability of diabetic patients based on the levels of nitric oxide related products such as nitrate or nitrite in urine or other specimens. Methods are also provided for treating non-wound healing diabetics and monitoring diabetic ulcer treatment.
Patent AU-627201-B2 (AU)
Title: Formulation chamber with exterior electrotransport delivery device
Inventor: THEEUWES FELIX
IPC: A61M5/14
Filed: 1989-07-19
Granted: 1992-08-20
Abstract: A drug delivery apparatus (10) is disclosed comprising a formulation chamber (24) and an electrotransport device (30) on the outside of the formulation chamber (24) for transporting an electrically charged drug (32) from the outside into a medical fluid (12) that flows through the formulation chamber (24) over drug delivery time.
Patent AU-664893-B2 (AU)
Title: Polypeptides having kinase activity, their preparation and use
Inventor: HILES IAN D
IPC: A61P7/00
Filed: 1993-04-13
Granted: 1995-12-07
Abstract: This invention relates to new polypeptides which exhibit kinase activity or, more specifically, which show phosphoinositide (PI)3-kinase activity. Such polypeptides are involved in pathways responsible for cellular growth and differentiation. An isolated polypeptide which possesses PI3-kinase activity when produced by recombinant production in insect cells is disclosed.
Patent AU-588797-B2 (AU)
Title: Self-fill system
Inventor: JACOBS LEONARD
IPC: B67D1/10
Filed: 1985-03-04
Granted: 1989-09-28
Abstract: In connection with a beverage dispensing machine, an automatic self-fill control apparatus for the machine for controlling the filling of the liquid tank, which liquid tank is fed with a combination of water and a concentrate syrup adapted to be mixed with the water within the tank. A sensor member is disposed in the tank in a position so as to be responsive to the rise and fall of liquid in the tank. Pump means are provided adapted to pump the syrup to the tank. Control of water flow to the tank is also carried out. The sensor member has a low probe for detecting a low predetermined level of liquid in the tank and a high probe for detecting a high predetermined level of liquid in the tank and adapted to respectively generate low and high probe signals. Control circuit means is provided receiving and responsive to these low and high probe signals for controlling the pump to operate when the low probe is uncovered and terminating the pumping action when the liquid level reaches the high probe position so that the liquid level in the tank is always maintained at a level between the low and high probes. Also provided is a third sensor for determining an unsafe condition referred to herein as a system override to shut the system down in the event that the high probe is covered and that the liquid level proceeds to the even higher third probe. Also in the system of the present invention, there is provided a sensor for detecting an out-of-syrup condition.
Patent AU-693294-B2 (AU)
Title: An expandable intraluminal vascular graft
Inventor: LAZARUS HARRISON M
IPC: A61F2/02
Filed: 1996-01-10
Granted: 1998-06-25
Abstract: An intraluminal grafting system (11) includes a hollow graft (12) which has a proximal staple (16) and a distal staple (17). The system (11) includes a capsule (18) for transporting the graft (12) through the lumen and for positioning the graft (12)upstream in a lumen which may be a blood vessel or artery. A tube (26) is connected to the capsule (18) and extends to exterior the vessel for manipulation by the user. A catheter (27) is positioned within the tube (26) to extend from the cavity and through the graft (12) to exterior the body. The catheter (27) has an inflatable membrane (3)which is in communication via a channel with inflation and deflation means (38). With the inflatable membrane (30) deflated, the capsule (18) is positioned in the lumen and manipulated to desired location. The force exerted by the inflatable membrane (30) and the structure of the staples urges the staples in the vessel, retaining the graft in position. <IMAGE>
Patent AU-754434-B2 (AU)
Title: Novel inhibitors of NF-kappaB activation
Inventor: BEYAERT RUDI
IPC: A61P11/00
Filed: 1999-05-05
Granted: 2002-11-14
Abstract: The present invention relates to novel inhibitors of the Nuclear factor kappa B (NF-kappaB) activating pathway useful in the treatment of NF-kappaB related diseases and/or in the improvement of anti-tumor treatments. These inhibitors interfere early in the TRAF induced signaling pathway and are therefore more specific than IkappaB.
Patent AU-696733-B2 (AU)
Title: Biopsy forceps for obtaining tissue specimen and optionally for coagulation
Inventor: COX DENNIS
IPC: A61B10/02
Filed: 1995-11-08
Granted: 1998-09-17
Abstract: A biopsy forceps as disclosed that has a flexible hollow support cable with an insulating layer surrounding the support cable on its outer surface. An electrically conductive control wire extends through a central passage of the hollow support cable and has an insulating layer surrounding the portion of the control wire that is inside the support cable. The control wire is connected to an electrically conductive mount at a distal end of the control wire. The electrically conductive mount supports the pair of electrically conductive metal jaws which are pivotal and which have curved walls with sharp cutting edges which together form an enclosure for purposes of excising tissue. The control wire is electrically connected to a source of electrical current to permit selective energizing of the control wire as well as mechanical closing of the jaws when excising tissue, so as to provide simultaneous energizing of the mount, the pivotal jaws and also conductive spear for stabilizing and holding tissue that is positioned between the jaws.
Patent AU-682664-B2 (AU)
Title: Edible plastic dispersion having a rapid gel-setting starch
Inventor: WESDORP LEENDERT HENDRIK
IPC: A23D7/005
Filed: 1993-06-04
Granted: 1997-10-16
Abstract: An edible plastic dispersion not having a continuous fat phase, including at least two condensed phases, at least one of which is continuous, the dispersion comprising a first gel-forming composition and a second gel-forming composition containing 1-8 times the critical concentrations of a gelling starch having a rheological property in an aqueous dispersion characterized by a one-half G'max value at no more than about 7,250 seconds when prepared at a concentration to yield a log G'max value of 5.0 at 15,000 seconds at 11 DEG  C. provided that the aqueous dispersion of the gelling starch is initially prepared at 0 to 40 DEG  C.
Patent AU-666207-B2 (AU)
Title: Deactivator reagent for olefin polymerization catalysts
Inventor: KAO SUN-CHUEH
IPC: C08F2/42
Filed: 1993-08-25
Granted: 1996-02-01
Abstract: A method is disclosed for controlling the activity of or deactivating a transition element olefin polymerization catalyst by contacting the catalyst with a 1,2-diether organic compound.
Patent AU-661917-B2 (AU)
Title: Removing ions from solutions using sulphur containing hydrocarbon complex and electron withdrawing groups
Inventor: BRUENING RONALD L
IPC: B01J15/00
Filed: 1993-06-08
Granted: 1995-08-10
Abstract: A method for the removal and concentration of desired ions such as Pd(II), Ru(III), Pd(IV), Au(III), Au(I), Ag(I), and Hg(II) from a multiple ion source solution which may contain larger concentrations of other undesired ions including H+ comprises bringing the source solution into contact with a compound comprising a sulfur and electron withdrawing group containing ligand covalently bonded through an organic spacer silicon grouping to a solid inorganic support. The sulfur and electron withdrawing group containing ligand portion(s) of the compound has an affinity for the desired ions to form a complex thereby removing the desired ions from the source solution. The desired ions are removed from the compound by contacting the compound with a much smaller volume of a receiving solution having a greater affinity for the desired ions than does the sulfur and electron withdrawing group containing ligand portion of the compound. The process is useful in removing desired or unwanted ions from acidic waste streams, metal refining streams, and other industrial or environmental streams. The invention is also drawn to the sulfur and electron withdrawing group containing ligands covalently bonded through a spacer grouping to a hydrophilic inorganic solid support material.