baber/WOPTO huggingface dataset:
Patent NO-167746-B (NO)
Inventor: HARTMANN ALBERT
IPC: A61K31/70
Filed: 1983-07-22
Abstract: The compounds of the formula I    <IMAGE>  (I)    <IMAGE>  in which each of R1, R4 and R6, independently of the others, represents hydrogen or lower alkanoyl, R2 represents C1-4-alkyl, hydroxymethyl or phenyl, R3 represents hydrogen or methyl, R5 represents hydrogen or C1-3-alkyl, R7 represents C1-3-alkyl that is unsubstituted or substituted by hydroxy, mercapto or methylthio, R8 represents hydrogen or lower alkyl, X represents oxygen or the group NH, Y represents C1-4-alkylidene, and each of R9 and R10, independently of the other, represents C11-17-alkyl or C11-17-alkenyl, and their salts, have an immunostimulating activeity.
Patent NO-167268-B (NO)
Inventor: WILLEMSEN HENRICUS PETRUS
IPC: B29C53/08
Filed: 1983-07-29
Abstract: A method for the production of a hose (4) of a shape-cured elastomeric material, such as vulcanized rubber, especially an automotive radiator coolant hose, which method comprises the bringing of the hose (4) onto a flexible straight mandrel (3), sliding the flexible mandrel (3) onto an inner mandrel portion (7) having the finally desired configuration of the hose (4), curing the hose (4) in this configuration, sliding the flexible mandrel (3) together with the hose (4) of said inner mandrel portion (7) and bringing the flexible mandrel (3) onto a straight auxiliary mandrel (10) and sliding the hose (4) of the mandrel (3).
Patent NO-159813-B (NO)
Title: Boretaarn.
Inventor: SWISHER ROGER C
IPC: E21B/
Filed: 1985-07-04
Abstract: Boretårn (1) for boring og vedlikehold av olje og/eller gassbrenner hvor det på boredekket er installert et portalformet boretårn dannet av en øvre travers (2) og to i innbyrdes avstand beliggende, stort sett parallelle, opprettstående tårnkomponenter (3, 4) som mellom seg avgrenser et fritt rom (S), hvori en hydraulisk heisemaskin (6) som er tilkoplet en boremaskin (18) for borestrengen (15), er innrettet til å løpe langs stasjonære, opprettstående tann-stangskinner (10), idet den vertikalt forskyvbare heisemaskin (6) på i og for seg kjent måte drives ved hjelp av hydrauliske motorer som med tannhjul (9). griper inn i tannstangskinnene (10).
Patent NO-170935-B (NO)
Inventor: KASZTREINER ENDRE
IPC: C07D498/04
Filed: 1986-12-30
Abstract: The invention relates to novel pyrimido [5,4-b][1,4]oxazine derivatives of the formula (I), and the acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the formula (I)    <IMAGE>  (I)  wherein R1 stands for a C1-4 alkyl group; R2 stands for hydrogen or halogen or an azido group or an -NR5R6 group, wherein R5 represents hydrogen or a benzyl group, or a C1-4 alkyl group unsubstituted or substituted by a hydroxyl group, R6 stands for hydrogen, an amino group, a C3-6 cycloalkyl group, a straight or branched-chain C1-4 alkyl group optionally substituted by a hydroxyl, mercapto, aminocarbonyl, furyl, 2-benzo[1,4]dioxanyl, di(C1-4 alkyl)amino group or by a phenyl or phenoxy group optionally mono- or polysubstituted by halogen or C1-4 alkoxy group (s) or by a 6-membered, saturated nitrogen-containing heterocycle optionally containing an additional nitrogen or oxygen atom and optionally substituted by a C1-4 alkyl or benzyl group; further NR5R6 may also represents a 6-membered, saturated, nitrogen-containing heterocycle optionally containing an additional nitrogen or oxygen atom and optionally substituted by a C2-4 alkoxycarbonyl or C1-4 hydroxyalkyl group; R3 and R4 are the same or different and stand for hydrogen or a C1-4 alkyl group; R9 stands for hydrogen or a C1-4 alkyl group unsubstituted or monosubstituted by an oxo, cyano, aminocarbonyl, C2-5 alkoxycarbonyl, pyridiyl, morpholinocarbonyl, or phenyl group or mono- or polysubstituted by OH group(s), with the proviso that R2 is different from chlorine, 4-morpholinyl and piperidyl group when R9 stands for hydrogen; or R2 is different from chlorine and 4-morpholinyl group when R9 stands for a methyl or benzyl group. The compounds of the formula (I) are capable to increase the myocardial contractile force (the performance of the failing heart) and the coronary blood flow, thus they can therapeutically be used for the treatment of the chronic heart failure and coronary disturbances.
Patent SE-315024-B (SE)
Inventor: HOLUB F
IPC: C08G63/19
Filed: 1965-06-11
Abstract: In the manufacture of polycarbonates by heating together a dihydric phenol and a bis-haloformate of a dihydric phenol with evolution of hydrogen halide, the reaction is effected in the presence of a solvent which is benzophenone, m-terphenyl, a chlorinated or brominated biphenyl, a chlorinated or brominated diphenyl oxide or a chlorinated or brominated naphthalene. Heating is effected at a temperature from 270 DEG  C. to the reflux temperature, possibly in the presence of a tertiary amine as catalyst.  The reaction mixture may also include a di-acid halide of an aromatic dicarboxylic acid or a chain-stopper which is a monohydric phenol or an acid halide of a monocarboxylic acid.  The dihydric phenols are preferably dihydroxy benzenes, dihydroxy diphenyls, dihydroxy naphthalenes or their halogenated derivatives.  They may also be bisphenols in which the radical joining the two hydroxyaryl groups may be one or more radicals selected from alkylene, alkylidene, tertiary amino, ether, carbonyl, sulphide, sulphoxide, sulphore and siloxy radicals and in which the hydroxyaryl groups may be substituted by halo, nitro-, hydrocarbyl or hydrocarbonoxy radicals.  The aromatic dicarboxylic acid may be phthalic, isophthalic, terephthalic or a naphthalene dicarboxylic acid or halogen substituted derivatives thereof.  At the end of the polymer-forming reaction, the polymer may be precipitated from the solvent by the addition of a non-solvent or, alternatively, the solvent may be removed by spray-drying or evaporation. In examples, polymers are made by reacting: (1) hydroquinone and resorcinol bischloroformate; (2) hydroquinone, hydroquinone bischloroformate and resorcinol bischloroformate; (3) chlorohydroquinone and hydroquinone bischloroformate; (4) hydroquinone and chlorohydroquinone bischloroformate; (5) bisphenol A and bisphenol A bischloroformate; (6) hydroquinone and bisphenol A bischloroformate; (7) hydroquinone, hydroquinone bischloroformate and isophthaloyl chloride by a one- or two-stage process; (8) hydroquinone, hydroquinone bischloroformate and 5 - chloroisophthaloyl chloride; (9) hydroquinone, resorcinol bischloroformate and isophthaloyl chloride; or hydroquinone, resorcinol, hydroquinone bischloroformate and isophthaloyl chloride by a one- or two-stage process; or hydroquinone, hydroquinone bischloroformate, resorcinol bischloroformate and isophthaloyl chloride; or hydroquinone, resorcinol, resorcinol bischloroformate, isophthaloyl chloride and terephthaloyl chloride by a one- or two-stage process.  Reference is also made to reacting catechol with the bischloroformate of hydroquinone or resorcinol.  Uses.-Films, fibres, electrical insulation or dielectrics, adhesives. Specification 984,524 is referred to.
Patent YU-48294-B (YU)
Inventor: LS CLEGG
IPC: A61K31/415
Filed: 1992-12-23
Abstract: PCT No. PCT/EP92/02899 Sec. 371 Date Jun. 3, 1994 Sec. 102(e) Date Jun. 3, 1994 PCT Filed Dec. 12, 1992 PCT Pub. No. WO93/13075 PCT Pub. Date Jul. 8, 1993This invention relates to compounds of formula I and pharmaceutically acceptable salts thereof   represent hydrogen, halo, alkyl, alkoxy, phenoxy, phenyl, alkoxycarbonyl, -NR13R14, halogenated alkoxy, halogenated alkyl, benzyloxy, hydroxy, hydroxyalkyl, (C2-6 alkoxycarbonyl)vinyl, -S(O)nR7, carbamoylalkyl, alkoxycarbonylalkyl, -CONR11R12, or R1 and R2 together with the phenyl ring represent a naphthyl group; R4 and R5 independently represent hydrogen, alkyl, phenyl or together with the carbon atom represent C3-6 cycloalkyl; R6 represents hydrogen, alkyl or  omega -hydroxy alkyl; A represents C2-9 alkylene; R8 represents hydrogen, alkyl, halo, alkoxy, hydroxyalkyl, benzyl or phenyl; R9 and R10 independently represent hydrogen, alkyl, halo, alkoxy, phenyl, hydroxyalkyl, alkoxycarbonyl, nitro, -NR30R31, alkanoyloxyalkyl, or aminomethyl; which are antiinflammatory and antiallergic agents. Compositions containing these compounds and processes to make them are also disclosed.
Patent YU-45833-B (YU)
Title: Kompozicija akrilnog hidrosola za prevlake i postupak za njihovo dobijanje
Inventor: COWLES R A
IPC: C09D133/04
Filed: 1987-09-23
Abstract: KOMPOZICIJA AKRILNOG HIDROSOLA ZA PREVLAKE I POSTUPAK ZA NJIHOVO DOBIJANJE, naznačen time, što sadrži ravnomerno dispergovane čestice pigmenta u količini od 0,5 do 40 mas.% u vodenom rastvoru organskog rastvarača, najpogodnije diaceton alkohola i izopropanola u ukupnoj količini od oko 35 do 65 mas.% u prisustvu u vodi rastvorne soli disperznog polimera sa kiselim funkcionalnim grupama, kao što je akrilni polimer, poliestarski polimer, epoksi estarski polimer, alkilni polimer ili uretanski polimer, u količini od oko 1 do 5mas.% u obliku stabilne disperzije i jednoobraznu vodenu disperziju čestica akrilnog hidrosola u količini od oko 5 do oko 40 mas.%. Prijava sadrži još 4 patentna zahteva.
Patent YU-46039-B (YU)
Inventor: KASZTREINER E
IPC: C07D498/04
Filed: 1986-12-30
Abstract: The invention relates to novel pyrimido [5,4-b][1,4]oxazine derivatives of the formula (I), and the acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the formula (I)    <IMAGE>  (I)  wherein R1 stands for a C1-4 alkyl group; R2 stands for hydrogen or halogen or an azido group or an -NR5R6 group, wherein R5 represents hydrogen or a benzyl group, or a C1-4 alkyl group unsubstituted or substituted by a hydroxyl group, R6 stands for hydrogen, an amino group, a C3-6 cycloalkyl group, a straight or branched-chain C1-4 alkyl group optionally substituted by a hydroxyl, mercapto, aminocarbonyl, furyl, 2-benzo[1,4]dioxanyl, di(C1-4 alkyl)amino group or by a phenyl or phenoxy group optionally mono- or polysubstituted by halogen or C1-4 alkoxy group (s) or by a 6-membered, saturated nitrogen-containing heterocycle optionally containing an additional nitrogen or oxygen atom and optionally substituted by a C1-4 alkyl or benzyl group; further NR5R6 may also represents a 6-membered, saturated, nitrogen-containing heterocycle optionally containing an additional nitrogen or oxygen atom and optionally substituted by a C2-4 alkoxycarbonyl or C1-4 hydroxyalkyl group; R3 and R4 are the same or different and stand for hydrogen or a C1-4 alkyl group; R9 stands for hydrogen or a C1-4 alkyl group unsubstituted or monosubstituted by an oxo, cyano, aminocarbonyl, C2-5 alkoxycarbonyl, pyridiyl, morpholinocarbonyl, or phenyl group or mono- or polysubstituted by OH group(s), with the proviso that R2 is different from chlorine, 4-morpholinyl and piperidyl group when R9 stands for hydrogen; or R2 is different from chlorine and 4-morpholinyl group when R9 stands for a methyl or benzyl group. The compounds of the formula (I) are capable to increase the myocardial contractile force (the performance of the failing heart) and the coronary blood flow, thus they can therapeutically be used for the treatment of the chronic heart failure and coronary disturbances.
Patent ZA-843288-B (ZA)
Title: Fluoroalkoxy compounds,processes for their preparation,their use and medicaments containing them
Inventor: RAINER GEORG
IPC: A61K31/44
Filed: 1984-05-03
Abstract: Fluoroalkoxy compounds of the general formula I    <IMAGE>  (I) wherein R1 represents a 1-3C-alkyl radical which is completely or predominantly substituted by fluorine, or a chlorodifluoromethyl radical, R1' represents hydrogen, halogen, trifluoromethyl, a 1-3C-alkyl radical, or a 1-3C-alkoxy radical which is optionally completely or predominantly substituted by fluorine, R2 represents hydrogen or a 1-3C-alkyl radical, R3 represents hydrogen or a 1-3C-alkyl or 1-3C-alkoxy radical, R4 represents hydrogen or a 1-3C-alkyl radical and n represents the number 0 or 1, and their salts are new compounds with a marked protective effect on the stomach.
Patent ZA-848249-B (ZA)
Title: Device for driving an oscillating spout
Inventor: MAILLIET PIERRE
IPC: F16H37/16
Filed: 1984-10-22
Abstract: An apparatus for driving an oscillating spout capable of pivoting about two orthogonal axes under the action of a pivoting control arm having the same degrees of liberties as the spout is presented. The driving apparatus includes a control mechanism which directs the control arm to perform the movement required by the spout and a transmission device which acts to transmit the control arm movement to the spout to reproduce it as spout movement, and vice versa. The apparatus further includes a rotary internal housing supported on a support frame via a bearing member and enclosed by an outer housing or cowl. The rotary housing is associated with a toothed rim which is actuated by a first motor fixed to or adjacent to the support frame. A control mechanism is also provided which includes a driving rod which is coaxial with the rotary internal housing and which is capable of sliding in the axial direction. The control mechanism is associated with a second motor which is also adjacent to or fixed to the support frame. A pivotal connecting means consisting of a central body and two diametrically opposed pivots is mounted on the lower end of the driving rod via one or more bearings in such a way so as to be freely rotatable in relation to the rod (and in conjunction with the rotary housing) but integral therewith with regard to vertical or axial movement. The pivotal connecting means is associated with the rotary housing such that a high rate of rotation may be transferred thereto.
Patent ZA-851668-B (ZA)
Title: Blood pump
Inventor: LUNDBAECK STIG
IPC: A61M60/876
Filed: 1985-03-05
Abstract: A blood pump comprises an atrium chamber defined by flexible walls and having an inlet and an outlet, a ventricle chamber defined by flexible walls and having an inlet and an outlet, a passage communicating the outlet of the atrium chamber with the inlet of the ventricle chamber, a first one-way valve in the passage adapted to permit blood flow only from the atrium chamber to the ventricle chamber, and a second one-way valve in the outlet from the ventricle chamber adapted to permit blood to flow through the outlet only out of the ventricle chamber. The chambers are movably supported in a casing having first and second openings, the atrium chamber inlet being fastened to the first opening and the ventricle chamber outlet to the second opening. A drive device cyclically moves the walls of the ventricle chamber to decrease its volume and expel blood from it while simultaneously moving the walls of the atrium chamber such that its volume may increase upon inflow of blood into the inlet to it. The drive device includes a drive ring surrounding and joined to the passage and having a surface engageable with the walls. of the ventricle chamber over a selected area such that the pressure of blood entering the chambers between driven strokes of the drive device controls the output of the blood pump by establishing the magnitude of the return stroke of the drive ring as a function of a pressure force acting over the area of engagement between the drive ring and the walls of the ventricle chamber.
Patent ZA-856209-B (ZA)
Title: An entangled nonwoven fabric with thermoplastic fibers on its surface and the method of making same
Inventor: MAYS ALFRED T
IPC: D04H1/54
Filed: 1985-08-15
Abstract: There is disclosed an entangled nonwoven fabric having a layer of fusible fibers on one or both surfaces of a relatively thick layer of base fibers. The fusible fibers are either homofil or conjugate fibers having an exposed low melting point component which have a lower melting temperature than the base fibers. The thermoplastic fibers are located on the outer surface of the base fibers either prior to or subsequent to the entangling of the fibers. The mixture of base and thermoplastic fibers are then heated to a temperature to heat fuse the homofil fibers or the low melting point component of the conjugate fibers.
Patent ZA-863639-B (ZA)
Title: Polyene antibiotic emulsion formulation
Inventor: KIRSH RICHARD LLOYD
IPC: A61K31/70
Filed: 1986-05-16
Abstract: A polyene antibiotic emulsion formulation comprising an antibiotic incorporated into an oil-in-water emulsion, and the use of the formulation in treating an active infection in an animal caused by a microorganism with sterols in its cell membrane by parenterally administering the emulsion formulation.
Patent ZA-907138-B (ZA)
Title: Carton and blank for making the same
Inventor: CURRY ERNEST
IPC: B65D5/06
Filed: 1990-09-07
Abstract: A carton made from a single blank of cardboard, paperboard or the like has a top having a rear portion which is substantially horizontal and a front portion which slopes downwardly and forwardly from said rear portion. The front portion may receive a dispensing spout. The carton is filled by first forming the top of the carton, then filling the carton through the open base and then closing the base. A blank for making the carton has top forming panels, and tuck forming panels connected between the top forming panels and side wall forming panels, the latter connection being by way of a hinge line with two contiguous sections at an angle to each other.
Patent ZA-922130-B (ZA)
Title: Long-acting biodegradable microparticles and a process for their preparation
Inventor: LILL NORBERT
IPC: A61K38/28
Filed: 1992-03-24
Abstract: Long-acting biodegradable microparticles containing therapeutically active peptides as active ingredient and poly(lactide-co-glycolide) as vehicle, which are obtained by spray drying at temperatures below 60 DEG C with a spray flow above 500 l(STP), are described.
Patent ZA-926277-B (ZA)
Title: 1-(alkoxybenzyl)piperazine amide compounds, process for preparing them and pharmaceutical compositions containing them.
Inventor: GAUDRY MICHEL
IPC: C07D295/18
Filed: 1992-08-20
Abstract: Compounds of formula (I): <IMAGE>  with R1, R2 and n as defined in the description. Medicaments.
Patent ZA-934893-B (ZA)
Title: Gelled organic liquids
Inventor: WESLEY JOHN N
IPC: C08J3/11
Filed: 1993-07-07
Abstract: Organic liquids can be very effectively gelled by using in combination with an amine neutralized anionic polymer an auxiliary rheological additive. The auxiliary rheological additive is a substance which increases the linearity of the anionic polymer and its thixotropic properties. Suitable auxiliary rheological additives are fatty acids and/or fatty acid salts optionally in combination with amphoteric oxides. The organic liquids that can be effectively gelled are organic solvents which include fuels such as hydrocarbons and alcohols.
Patent ZA-936813-B (ZA)
Title: Method and kits for detection of bacteria.
Inventor: SANDERS MICHAEL FREDERICK
IPC: C12Q1/66
Filed: 1993-09-15
Abstract: A method for detection, identification and/or quantification of target organisms of specific bacterial genus, species or serotype, based upon the occurrence of release of cell contents, particularly nucleotides e.g. ATP, on lysis of bacterial cell walls on incubation with bacteriophages (phages) specific for them. When new phage particles are released at the end of the phage replication cycle nucleotide levels are measured and compared with controls. The method provides for the detection of specific bacteria in which insertion of the lux gene into the phage genome is not required yet it is faster and more sensitive than known non-modified phage utilising techniques. The method is only limited by the availability of phage types suitable for selective attack of the target bacteria to be detected and can detect a single Salmonella in a sample of milk in under 12 hours.
Patent ZA-942037-B (ZA)
Title: Process for the preparation of a liposome dispersion under elevated pressure conditions
Inventor: FREDERIKSEN LENE
IPC: A61K9/127
Filed: 1994-03-23
Abstract: The invention relates to an advantageous process for preparing liposomes for inclusion of water-soluble or hydrophilic substances or mixtures of substances, which by comparison with known processes provides the surprising advantage of increasing the content of actually included substances or mixtures of substances and, on pharmaceutical use, the advantage of sterile operating conditions. This entails a mixture consisting of at least one phospholipid and conventional lipophilic auxiliaries being exposed to a mobile support phase consisting of carbon dioxide and a polar organic solvent (modifier) under supercritical pressure and temperature conditions, decompressing the compressed mixed phase to atmospheric pressure, and transferring it into an aqueous phase containing a substance which has water-soluble or hydrophilic properties and is to be encapsulated in liposomes.
Patent ZA-955793-B (ZA)
Title: Benzothiadiazine compound process for its preparation and the pharmaceutical compositions which contain it
Inventor: CORDI ALEX
IPC: A61P25/18
Filed: 1995-07-12
Abstract: (3aS)-5,5-Dioxo- 2,3,3a,4-tetrahydro- 1H-pyrrolo (2,1-c) (1,2,4) benzothiadiazine of formula (I) and its salts are new.
Patent ZA-962059-B (ZA)
Title: Control of expansion in concrete due to alkali silica reaction
Inventor: GAIDIS JAMES MICHAEL
IPC: C04B103/60
Filed: 1996-03-14
Abstract: A cement composition including spodumene which has been heated to at least 1000 DEG  C. which is capable of inhibiting expansion of the concrete due to the alkali-silica reaction. The present invention also provides a method of reducing expansion in cement compositions.
Patent AT-413349-B (AT)
IPC: B26D1/28
Filed: 2002-07-03
Granted: 2006-02-15
Abstract: Disclosed is a device for cutting a bar of material, comprising a bar-guiding unit (1) which has a guiding axis (10) that runs in the longitudinal direction of the bar, and a cutting tool (3) which is driven around a rotating shaft (4) that runs parallel to the guiding axis (10) and is provided with at least one knife. Said knife comprises at least one blade (7) which extends at least across one section of the circumference, runs in a spiraling manner around the rotating shaft (4), and is located on a surface of revolution having the rotating shaft (4) as an axis of rotation. The radial distance of the blade (7) from the rotating shaft (4) increases along the peripheral extension thereof counter to the sense of rotation at least by a degree that corresponds to the maximum cutting depth. In order to create advantageous cutting conditions, the inventive bar-guiding unit (1) comprises a guiding cylinder (2) that is provided with an engaging opening (9) for the knife, which is delimited by the cutting surface (12) between the guiding cylinder (2) and the surface of revolution defined by the blade (7).
Patent GB-2368737-B (GB)
Title: Method and apparatus for controlling an amplifier
Inventor: COBLEY KEVIN
IPC: H03G3/30
Filed: 2000-10-31
Granted: 2004-11-10
Abstract: A method and apparatus are described for controlling the operation of an amplifier, in which, a bias level applied to the amplifier is adjusted so as to generate an output signal having the desired level of peak to mean ratio.
Patent GB-2371896-B (GB)
Title: Web server
Inventor: WATSON MARK ALEXANDER
IPC: G06F17/30
Filed: 2001-09-24
Granted: 2005-11-09
Abstract: A web server (1) responds to a request message from a remote user device (2) by dynamically generating web page code capable of being interpreted by the user device. A device type identifier (45) is extracted from the request message and is input to a code generating engine (25) which interprets stored instructions for generating the web page code with reference to selected device dependent information corresponding to the device type identifier. The web page information is stored as a content document comprising a set of instructions written in a script language. The web server generates web pages in an appropriate form for each user device without the need to convert web pages from one form to another.