baber/WOPTO huggingface dataset:
Patent ZA-200509835-B (ZA)
Title: Use of angiotensin II receptor antagonists, espcially telmisartan, in order to increase insulin sensitivity
Inventor: STEFAN KAUSCHKE
IPC: A61P5/50
Filed: 2005-12-05
Abstract: Angiotensin II receptor antagonist is used to prepare a medicament for treating people for whom type 2 diabetes has been diagnosed or prediabetes is suspected, for preventing diabetes or for treating metabolic syndrome and insulin resistance in patients with normal blood pressure. An independent claim is also included for a composition comprising telmisartan in combination with: amlodipine or nifedipine; eplerenone or spironolactone; simvastatin or atorvastatin; rosiglitazone, pioglitazone, repaglinide or metformin; dipyridamol or clopidogrel, optionally in combination with aspirin; an aldosterone antagonist; a HMG-CoA reductase inhibitor; a dipeptidyl peptidase 4 inhibitor; a sulfonylurea; or a thrombocyte aggregation inhibitor. ACTIVITY : Antidiabetic. MECHANISM OF ACTION : Angiotensin II Receptor Antagonist; Peroxisomal Proliferator Activated Receptor Gamma (PPARgamma) Activator. PC12W cells overexpressing PPARgamma 2 and its heterodimer partner RXRalpha were treated with telmisartan (10 MicroM). PPARgamma activity was increased by a factor of 1.9.
Patent ZA-200601299-B (ZA)
Title: Disposal area for storing substances, composite substances or mixtures thereof, method for treating the same, and corresponding device
Inventor: CHRISTOPH MUTHER
IPC: B03B/
Filed: 2006-02-13
Abstract: In a waste disposal site for storing waste and residues of solid organic or inorganic substances, composites and mixtures thereof, arranged in the ground ( 22 ) is a trough comprising a trough bottom ( 14 ) and side walls, the trough bottom of which contains at least two water-tight layers (B, C) with constituents of a ceramic binder system (CBS). Arranged flat between the top water-tight layer (C) and the waste material ( 24 a) is at least one water-tight plastic film ( 26 ) on which compacted debris is stored as waste material ( 24 a). Moreover, there is a covering which contains at least two water-tight layers (B, C) on which there is arranged at least one seepage layer for dissipating rainwater.
Patent ZA-200609261-B (ZA)
Title: Fused quinoline derivative and use thereof
Inventor: MASAHIRO KAJINO
IPC: C07D471/04
Filed: 2005-04-28
Abstract: Use of a compound represented by the formula (I)   
wherein 
R 1  is (1) unsubstituted, (2) a hydrogen atom, (3) a hydrocarbon group optionally having substituent(s) or (4) acyl; 
R 2  is (1) a hydrogen atom, (2) a hydrocarbon group optionally having substituent(s), (3) hydroxy optionally having a substituent, (4) amino optionally having substituent(s), (5) thiol optionally having a substituent, (6) a heterocyclic group optionally having substituent(s) or (7) acyl; 
R 3  is (1) unsubstituted, (2) a hydrogen atom, (3) a hydrocarbon group optionally having substituent(s), (4) hydroxy optionally having a substituent, (5) amino optionally havingsubstituent(s), (6) thiol optionally having a substituent or (7) acyl; 
R 4  and R 5  are the same or different and each is (1) a hydrogen atom, (2) a hydrocarbon group optionally having substituent (s) ,  (3) hydroxyoptionallyhavingasubstituent, (4) amino optionally having substituent (s), (5) thiol optionally having a substituent or (6) acyl; 
R 6  is (1) (cyclic group optionally having substituent(s))-carbonyl, (2) alkenylcarbonyl optionally having substituent (s), (3) alkylcarbonyl having substituent (s) selected from (i) cycloalkyl optionally having substituent (s), (ii) amino optionally having substituent(s) and (iii) a heterocyclic group optionally having substituent(s) or (4) a heterocyclic group optionally having substituent(s); 
R 7 , R 8 , R 9  and R 10  are the same or different and each is (1) a hydrogen atom, (2) halogen, (3) cyano, (4) nitro, (5) a hydrocarbon group optionally having substituent(s), (6) hydroxy optionally having a substituent, (7) amino optionally having substituent(s), (8) thiol optionally having a substituent, (9) a heterocyclic group optionally having substituent(s) or (10) acyl; or 
R 7  and R 8 , R 8  and R 9 , and R 9  and R 10  may form a ring together with the adjacent carbon atoms; 
n is an integer of 1 to 5; 
--- represents unsubstituted or a single bond; and;  ---  represents a single bond or a double bond, or a salt thereof, for the production of an agent for the prophylaxis or treatment of melancholia.
Patent ZA-200706355-B (ZA)
Title: A method for the commercial production of iron
Inventor: GERARD PRETORIUS
IPC: C21B/
Filed: 2007-07-31
Abstract: A method for the production of iron from an iron oxide-containing material includes contacting an iron oxide-containing material with a particle size distribution range with a ∂90 of less than 2 mm, with a carbon-containing material with a particle size distribution range with a ∂90 of less than 6 mm, in a commercial scale reactor at a temperature of between 900° C. and 1200° C. for a contact time sufficient to reduce the iron oxide to iron.
Patent ZA-200709956-B (ZA)
Title: Pretreatment of a biological sample from an autoimmune disease subject
Inventor: KRISTA MCCUTCHEON
IPC: A61K/
Filed: 2006-05-19
Abstract: The present application describes a method for pretreating a biological sample from an autoimmune disease subject in order to avoid interference, especially where the sample is to be subjected to a cell-based biological activity assay, such as a neutralizing antibody assay.
Patent IN-153447-B (IN)
Inventor: WIRZ ARMIN
IPC: D02G1/16
Filed: 1980-09-15
Abstract: A texturising jet for synthetic filaments is openable and closable to facilitate lacing up. A lacing up system is operable in conjunction with the opening and closing mechanism so that the lace-up operation is semi-automatic. At least one of the parts of the jet has a flexible mounting to ensure face to face sealing contact of the parts when the jet is closed.
Patent MX-341701-B (MX)
Title: Closure system with orientation and removal capability.
Inventor: ALAN P HICKOK
IPC: B65D41/04
Filed: 2007-05-21
Abstract: A positive orientation container (30) and closure (32) combination is provided. The container (30) includes at least one flange segment (44) having a front (48) and a back face (52). The container (30) further includes a gap (60) defined by the front face (48) of one of the flange segments (44) and the back face (52) of one of the flange segments (44). The closure (32) includes a plurality of collar segments (70). The closure (32) includes at least one collar segment (70) having an engagement face (74) to establish a positive orientation of the closure (32) at a predetermined position.
Patent MX-337449-B (MX)
Title: Disposal and decontamination of radioactive polyvinyl alcohol products.
Inventor: KIM JIN-KIL
IPC: A62D3/00
Filed: 2010-11-12
Abstract: Methods and apparatus for decontaminating disposable protective products prepared from polyvinyl alcohol (PVA), used in a nuclear power plant, to less than minimum detectable activity (MDA) are disclosed. In the disclosed methods and apparatus, solid protective products made of PVA, generated from a nuclear power plant, are dissolved into a liquid, and then are decontaminated to less than MDA. The PVA solution decontaminated in this way is concentrated to an appropriate concentration or dried, and finally is subjected to self-disposal. This can fundamentally block the generation amount of combustible waste amounting to 50% or more of low and intermediate level waste of nuclear power plants, thereby considerably contributing to a reduction of the operating expenses of the nuclear power plants. The present invention further relates to methods and apparatus for self-disposing disposable protective products manufactured by conventional polyvinyl alcohol (PVA) through pyrolysis/catalytic oxidation of a PVA solution generated by concentration, and treating the decontaminated PVA solution within a plant. The PVA protective products are dissolved/concentrated/oxidized in water to remove firstly organic matter, and then PVA materials in the PVA solution are completely oxidized into CO2 and H2O by using a small-sized pyrolysis/catalytic oxidation reactor.
Patent MX-338769-B (MX)
Title: Deep-well pump system.
Inventor: BACH Jørgen
IPC: E21B43/12
Filed: 2010-12-04
Abstract: The invention relates to a deep-well pump system, comprising an immersion pump (20) and a riser (15) to be accommodated in the well, wherein a water treatment system for cleaning the pumped water is arranged in the riser (15).
Patent MX-347397-B (MX)
Title: Compartmentalized continuous micro-reactors for the production of biopharmaceuticals in ovary cells of chinese hamster.
Inventor: MARIO MOISES ALVAREZ
IPC: C12M3/00
Filed: 2012-12-17
Abstract: The present invention refers to a group of micro-devices that a) have a plurality of cylindrical-shaped compartments obstructed by a central structure (toroidal or doughnut-type compartments); b) have a texture in the surface of the channel that promotes the cellular adherence and the retention or proliferation of the recombinant cells of the mammal, particularly but not exclusively, ovary cells of Chinese hamster; c) are fed with a culture medium in a continuous manner by some type of pumping device. This plurality of micro-devices may be used in screening applications for culturing recombinant cells of mammals, particularly but not exclusively CHO cells, or for the production of biopharmaceuticals or other recombinant proteins.
Patent MX-354752-B (MX)
Title: Heterologous prime boost vaccination regimen against malaria.
Inventor: KATARINA RADOSEVIC
IPC: A61K39/015
Filed: 2011-09-07
Abstract: The invention provides methods for inducing an immune response in a subject against an antigen from a malaria-causing parasite, preferably P. falciparum, the method comprising: (i) administering to a subject a priming composition comprising adjuvanted proteinaceous antigen comprising circumsporozoite (CS) protein or immunogenic part thereof from a malaria-causing parasite; (ii) administering to the subject a first boosting composition comprising a recombinant adenovirus vector that comprises nucleic acid encoding CS protein or immunogenic part thereof from a malaria-causing parasite; and (iii) administering to the subject a second boosting composition comprising a recombinant adenovirus vector that comprises nucleic acid encoding CS protein or immunogenic part thereof from a malaria-causing parasite, wherein either the first boosting composition comprises a recombinant adenovirus vector of serotype 35 (Ad35) and the second boosting composition comprises a recombinant adenovirus of Ad26, or wherein the first boosting composition comprises a recombinant adenovirus vector of Ad26 and the second boosting composition comprises a recombinant adenovirus of Ad35.
Patent MX-352579-B (MX)
Title: Aerial splicebox for fiber optic cables.
Inventor: MARCOS AKINORI MASSUDA
IPC: G02B6/44
Filed: 2014-04-14
Abstract: Aerial splicebox for optic fiber cables, the box including: a base (10), the peripheral wall (11) which is provided with bottom windows (12) and top windows (14) and an external flange (13) articulating a cover (20) provided with a surrounding flange (23); a belt (40) to be fitted on said flanges (13,23), when sited against each other; a ring-shaped handle (50), having a closed end (51), hinged in the first end (41) of the belt (40) and a bipartite opposing end (52) which is moveable between an inoperative position and an operating position which is sited against the base (10) and aligned with the top windows (14); a fastener (60) mounted on the belt (40) in order to press the ring-shaped handle (50) against the base (10); and a sealing element (70) fixed against the peripheral wall (11) of the base (10) and provided with through openings (71) for optic cable (CO), aligned with the respective bottom windows (12) of the base (10).
Patent MX-359093-B (MX)
Title: SYSTEMS and METHODS FOR RENEWABLE FUEL.
Inventor: BARRY A FREEL
IPC: C10L1/18
Filed: 2012-12-11
Abstract: The present application generally relates to the introduction of a renewable fuel oil as a feedstock into refinery systems or field upgrading equipment. For example, the present application is directed to methods of introducing a liquid thermally produced from biomass into a petroleum conversion unit; for example, a refinery fluid catalytic cracker (FCC), a coker, a field upgrader system, a hydrocracker, and/or hydrotreating unit; for co-processing with petroleum fractions, petroleum fraction reactants, and/or petroleum fraction feedstocks and the products, e.g., fuels, and uses and value of the products resulting therefrom.
Patent MX-363795-B (MX)
Title: Method and arrangement for enhancing use of reactor volume in connection with hydrometallurgical leaching.
Inventor: JARI TIIHONEN
IPC: C22B3/20
Filed: 2012-12-18
Abstract: 2112057PC 17 (57) ABSTRACT The invention relates to a method for enhancing reactor volume use in a leaching stagein a hydrometallurgical process. According to the method, a concentrate or cal- cine leaching stageis carried out primarily using a plurality of reactors arranged in series, one or more reactors being provided with liquid-solid matter separation and the sepa- rated solid matter being transferred to one of the reactors in the leaching stage. Figure 2.
Patent MX-350461-B (MX)
Title: Combustion apparatus, and heating furnace using same.
Inventor: SHIGERU HANZAWA
IPC: F23L7/00
Filed: 2012-11-22
Abstract: Provided is a technology for uniformly increasing atmosphere temperature while rapidly achieving a desired uniform atmosphere composition. A combustion apparatus (500) is provided with: a combustion portion (100) including a combustion space (10) with a flammable gas inlet (30) which is an opening in the combustion space (10) for allowing the entry of a flammable gas, an air inlet (50) which is an opening in the combustion space (10) for allowing the entry of air, and a combustion gas outlet (70) for discharging combustion gas to the outside; and an adjusted gas passage portion (200) including an adjusted gas outlet (150) for discharging an adjusted gas adjusted to a desired composition to the outside, the adjusted gas outlet (150) located adjacent to the combustion gas outlet (70) and having an opening facing the combustion gas immediately after being discharged from the combustion gas outlet (70).
Patent MX-364220-B (MX)
Title: Methods of treating fibrosis.
Inventor: VITI FRANCESCA
IPC: A61K31/343
Filed: 2013-02-08
Abstract: The present disclosure is directed in part to methods of treating fibrosis, e.g., hepatic fibrosis and/or intestinal fibrosis, comprising administering to a patient in need thereof an effective amount of a disclosed compound.
Patent MX-352079-B (MX)
Title: Initiator device for a downhole tool.
Inventor: WILLIAM ROBERT TAPIE
IPC: E21B47/12
Filed: 2012-06-10
Abstract: A method of initiating a process in a downhole tool includes connecting a downhole tool to an initiator device that contains wires capable of creating a loopback and/or loaded condition when a closed connection is made. The initiator device is further capable of indicating successful initiation. The process to be initiated can be any process for which the tool has been programmed, such as the start of a countdown.
Patent MX-361761-B (MX)
Title: Triazole carboxamide derivatives.
Inventor: GUIDO GALLEY
IPC: A61K31/4196
Filed: 2013-09-13
Abstract: The invention relates to compounds of formula (I), wherein R1 is phenyl or pyridinyl, optionally substituted by halogen, lower alkyl, lower alkoxy, lower alkyl substituted by halogen and lower alkoxy substituted by halogen; X1 is -N= or CH; X2 is CR2 or =N-; X3 is -N= or CH; with the proviso that only two of X1, X2 or X3 are nitrogen; wherein is a triazole group, selected from R2 is hydrogen or lower alkyl; Z is a bond, -O- or -CH2-; or to pharmaceutically suitable acid addition salts thereof. It has now been found that the compounds of formulas I have a good affinity to the trace amine associated receptors (TAARs), especially for TAAR1. The compounds may be used for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress-related disorders, psychotic disorders such as schizophrenia, neurological diseases such as Parkinson's disease, neurodegenerative disorders such as Alzheimer's disease, epilepsy, migraine, hypertension, substance abuse and metabolic disorders such as eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
Patent MX-371356-B (MX)
Title: Prodrugs of amino quinazoline kinase inhibitor.
Inventor: CASILLAS LINDA N
IPC: A61P29/00
Filed: 2013-09-13
Abstract: Disclosed are compounds having Formula (I); wherein X is as defined herein, and methods of making and using the same.
Patent MX-355454-B (MX)
Title: Rotors and stators for dynamoelectric machines.
Inventor: CAO PINGSHAN
IPC: H02K1/14
Filed: 2013-03-14
Abstract: A dynamoelectric machine includes a rotor having a rotor core and permanent magnets, and a stator having teeth. The permanent magnets are arranged in magnet sets. Each magnet set includes one or more of the permanent magnets. The rotor core has a cylindrical periphery and slits. Each of the slits is positioned radially between one of the magnet sets and the cylindrical periphery. Each tooth includes a tooth surface facing the cylindrical periphery. The tooth surface includes an inner portion extending substantially parallel to the cylindrical periphery of the rotor core, and beveled portions positioned on opposing sides of the inner portion of the tooth surface. An air gap between each beveled portion of the tooth surface and the cylindrical periphery of the rotor core is greater than an air gap between the inner portion of the tooth surface and the cylindrical periphery of the rotor core.
Patent MX-370178-B (MX)
Title: SALT FORMS OF (S)-Quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol- 4-yl)propan-2-yl)carbamate.
Inventor: CRAIG SIEGEL
IPC: A61K31/439
Filed: 2014-03-14
Abstract: The present invention relates to novel salt forms of (S)-Quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate useful as an inhibitor of glucosylceramide synthase (GCS) and for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.
Patent MX-340887-B (MX)
Title: Apparatus of decoding video data.
Inventor: MOONOCK YANG
IPC: H04N19/593
Filed: 2012-11-02
Abstract: Provided is an apparatus that derives a luma intra prediction mode and a chroma intra prediction mode, determines a size of a luma transform unit and a size of a chromatransform unit using luma transform size information, adaptively filters the reference pixels of a current luma block based on the luma intra prediction mode and the size of the luma transform unit, generates prediction blocks of the currentluma block and the currentcurrent block and generates a residual luma residual block and a chroma residual block. Therefore, the distance of intra prediction becomes short, and the amount of coding bits required to encode intra prediciton modes and residual blocks of luma and chroma components is reduced and the coding complexity is reduced by adaptively encoding the intra prediction modes and adaptively filtering the reference pixels.
Patent MX-364318-B (MX)
Title: Haptic vehicle alert based on wearable device.
Inventor: CUDDIHY MARK A
IPC: B60W50/14
Filed: 2016-01-15
Abstract: A vehicle includes a controller that communicates with a wearable device having a haptic mechanism. In response to an alert event detected by the vehicle, the controller outputs a signal to activate the haptic mechanism. The wearable device may detect a physiological or biometric characteristic such as pulse rate. The controller may output a signal to activate the haptic mechanism further in response to the pulse rate being less than a threshold. Also, the controller may output a signal to activate the haptic mechanism while the vehicle is operating autonomously.
Patent MX-367709-B (MX)
Title: Cip wash comparison and simulation.
Inventor: JOSEPH P CURRAN
IPC: G06Q30/04
Filed: 2015-08-04
Abstract: One embodiment includes a method for simulating an operational effect of one or more changes in a CIP process. The method includes providing a graphical user interface configured to receive inputs from a user, receiving at least one proposed adjustment to one CIP phase of the CIP process, and generating a simulated CIP process based on a first set of CIP data and the at least one proposed adjustment to generate simulated CIP data based on the simulated CIP process. The simulated CIP data is displayed on the display. The simulated CIP data includes at least one of the amount or the total cost of each consumable used to generate the simulated CIP data. A total cost of the simulated CIP process is calculated, where the total cost of the simulated CIP process incorporates the proposed adjustment.
Patent MX-361034-B (MX)
Title: Gender-differentiated absorbent articles.
Inventor: SARA JANE WILLIE STABELFELDT
IPC: A61F13/491
Filed: 2014-08-27
Abstract: A method for manufacturing an absorbent article having a body facing liner, a backsheet coupled to the body facing liner, an absorbent body positioned between the body facing liner and the backsheet, and a fluid acquisition layer having a body facing surface and a garment facing surface, the fluid acquisition layer being positioned between the body facing liner and the backsheet includes providing a web of body facing liner material in face-to-face relation to a web of fluid acquisition layer material, bonding the body facing liner material to the fluid acquisition layer material using an embossing roller, wherein the embossing roller has an axis and a circumferential surface having a circumferential lane, the circumferential lane having azimuthally-alternating target zone and channel zone embossing patterns, and phasing the embossing roller relative to the web to produce female products and male products.
Patent MX-363352-B (MX)
Title: Apparatus and method for generating an enhanced signal using independent noise-filling.
Inventor: CHRISTIAN NEUKAM
IPC: G10L19/028
Filed: 2015-07-24
Abstract: An apparatus for generating an enhanced signal from an input signal (600), wherein the enhanced signal has spectral values for an enhancement spectral region, the spectral values for the enhancement spectral regions not being contained in the input signal (600), comprises a mapper (602) for mapping a source spectral region of the input signal to a target region in the enhancement spectral region, the source spectral region comprising a noise-filling region (302); and a noise filler (604) configured for generating first noise values for the noise-filling region (302) in the source spectral region of the input signal and for generating second noise values for a noise region in the target region, wherein the second noise values are decorrelated from the first noise values or for generating second noise values for a noise region in the target region, wherein the second noise values are decorrelated from first noise values in the source region.
Patent MX-365370-B (MX)
Title: A skin lightening composition comprising 4-hexylresorcinol and ilomastat.
Inventor: MAITREYEE DUTTA
IPC: A61Q19/02
Filed: 2015-11-24
Abstract: The present invention is in the field of personal care compositions; in particular skin lightening compositions. A more effective way to reduce melanin content in melanocytes remains to be desired. It has been found that 4-hexylresorcinol in combination with MMP inhibitor galardin synergistically reduces melanin content in melanocytes. The invention thus relates to a composition comprising a synergistic combination of 4-hexylresorcinol and galardin for use in skin lightening. Thus the composition, when applied topically over an appropriate length of time in-vivo, may be used to lighten the skin, or to reduce age spots or freckles.