baber/WOPTO huggingface dataset:
Patent EP-2339347-A1 (EP)
Inventor: O'DOWD BRIAN F
IPC: G01N33/68
Filed: 2003-04-11
Abstract: A method for screening a candidate compound for its ability to interact with at least one transmembrane protein comprising: 
transfecting a cell with at least one nucleotide sequence encoding a protein comprising a transmembrane protein containing at least one nuclear localisation sequence (NLS) and a detectable moiety and permitting expression of the encoded protein in the cell; 
contacting the cell with a candidate compound; and 
determining the distribution of the expressed protein in the cell by detecting the distribution of the detectable moiety in the cell; 
wherein detection of an altered distribution of the detectable moiety in the cell relative to the distribution of the detectable moiety in a control cell not contacted with the candidate compound indicates that the compound interacts with the transmembrane protein, and 
wherein the wild type transmembrane protein contains an NLS.
Patent EP-2336535-A1 (EP)
Inventor: HATTORI KOJI
IPC: F02D41/40
Filed: 2010-11-19
Abstract: To secure an appropriate fuel injection even when an environmental temperature is in a low temperature region, with a simple configuration, thus enabling a realization of a high stability and reliability fuel injection. 
     With a common rail fuel injection control apparatus configured capable of a multi injection, a temperature correction factor which suppresses a deterioration in a fuel injection amount correction when an environmental temperature is in a low temperature region is used when calculating a correction amount in the fuel injection amount correction executed in order to reduce a fuel injection amount pulsation occurring between a preceding fuel injection and a fuel injection succeeding a finishing of the preceding fuel injection in one engine cycle, and an appropriate fuel injection is secured by obtaining an appropriate correction amount even when the environmental temperature is in the low temperature region, thus enabling a realization of a high stability and reliability fuel injection.
Patent EP-2345743-A1 (EP)
Inventor: LAIRD PETER W
IPC: C12Q1/68
Filed: 2006-05-02
Abstract: Particular aspects confirm the existence of a CpG island methylator phenotype (CIMP) in colorectal cancer, and provide novel validated DNA methylation markers associated with CIMP. Additional aspects provide novel methods and compositions for: determining CIMP status in colorectal cancers, determining the relationship between CIMP status and other molecular features of the cancers (e.g., BRAF mutation, KRAS mutation and MSI status); determining the relationship between CIMP status and other variables (e.g., age, sex, tumor location, family history, race, country of origin, tumor characteristics (including, tumor type, tumor grade, invasive margin characteristics, lymphocyte infiltration characteristics, direct spread, lymph node spread, venous spread and type of residual adjacent polyp, if present)); and determining, between subgroups defined by CIMP status and BRAF mutations, effects of selected risk factors (e.g., body mass index, smoking history, alcohol intake, dietary folate intake, folate metabolic enzyme polymorphisms and history of hormonal use).
Patent EP-2343293-A1 (EP)
Inventor: LEBAN JOHANN
IPC: A61K31/454
Filed: 2005-07-29
Abstract: The present invention relates to compounds of the general formula (I)
     
and salts thereof, wherein 
R 1  is independently hydrogen, alkyl, cycloalkyl, hydroxyalkyl, haloalkyl, haloalkyloxy, aryl, substituted aryl, heteroaryl, substituted heteroaryl, arylalkyl or substituted arylalkyl; 
R 2  is independently
     
R 3  is independently alkyl, cycloalkyl, alkoxy, alkylamine, -OH, -SH, alkylthio, hydroxyalkyl, haloalkyl, haloalkyloxy, aryl or heteroaryl, 
R 4  is independently alkyl, cycloalkyl, alkoxy, alkylamine, alkylthio, hydroxyalkyl, haloalkyl, haloalkyloxy, aryl or heteroaryl; 
R 5  is independently H, COR 6 , CO 2 R 6 , SOR 6 , SO 2 R 6 , SO 3 R 6 , alkyl, cycloalkyl, alkoxy, -NH 2 , alkylamine, -NR 7 COR 6 , halogen, -OH, -SH, alkylthio, hydroxyalkyl, haloalkyl, haloalkyloxy, aryl or heteroaryl; 
R 6  is independently H, alkyl, cycloalkyl, -NH 2 , alkylamine, aryl or heteroaryl; 
R 7  is independently H, alkyl, cycloalkyl, alkoxy, -OH, -SH, alkylthio, hydroxyalkyl, aryl, or heteroaryl; 
p is 0, or 1; 
q is 0, or 1; 
X is CO, or SO 2 .
Patent EP-2460548-A1 (EP)
Inventor: MUELLER MARCEL
IPC: A61M5/158
Filed: 2010-12-06
Abstract: A method of preparing at least parts of a medical device for application and a medical assembly for preparing or storing the at least one disposable unit (1) of the medical device is disclosed. The medical assembly comprises a chemical or physical monitoring device (4) for counting and/or displaying a time period of application and/or remaining before required disposal or replacement of the disposable unit (1). The monitoring device (4) is automatically activated by moving the at least one disposable unit (1) relative to a second unit (2; 9; 18) of the medical assembly for: 
- preparing or positioning the disposable unit (1) for use with the medical device; 
- assembling the at least one disposable unit (1) and the medical device; and/or 
- withdrawing the disposable unit (1) of a storage compartment (3) of the second unit.
Patent EP-2450804-A1 (EP)
Inventor: BERNHARDT BRUCE ALLEN
IPC: G06F17/30
Filed: 2010-12-10
Abstract: An apparatus, and an associated method, facilitates selection of a media file for play-out at a media player, such as a media player forming part of a wireless device. Prioritization criteria is used to prioritize a plurality of media files according to a prioritization criteria. And, once prioritized, a playlist is established. The playlist is used in the selection of a media file to be played out at the media-file player.
Patent EP-2469762-A1 (EP)
IPC: H04L12/24
Filed: 2010-12-24
Abstract: The present invention provides a segmented network in which each segment comprises one or more routers, one or more communications links to provide connectivity between the router(s) and a segment management module. The segment management module uses operational data to predict the future performance of each element. If the predicted performance will breach a threshold value then a data flow may be re-routed. Re-routing between different segments can lead to network management problems and so the present invention discloses methods by which: segments can expand to acquire a router from another segment; segments can subdivide; and segments can merge together, particularly if a segment comprises too few routers.
Patent EP-2426505-A1 (EP)
Inventor: KARLA INGO
IPC: H04W64/00
Filed: 2010-09-06
Abstract: The invention relates to a method for localizing mobile terminals (M) in a radio network (1), the method comprising: emitting, by a mobile terminal (M) to be localized, a distance measuring signal (DMS), receiving the distance measuring signal (DMS) in a plurality of base stations (BS S , BS NS ) of a localization cluster (LC) which comprises a serving base station (BS S ) for the mobile terminal (M) and a plurality of further, non-serving base stations (BS NS ), determining distances of the mobile terminal (M) to the base stations (BS S , BS NS ) of the localization cluster (LC) based on the received distance measuring signal (DMS), and, in the localization cluster (LC), preferably in the serving base station (BS S ), localizing the mobile terminal (M) based on the determined distances. The invention also relates to a base station (BS S ), and to a network (1) comprising a plurality of base stations (BS S ).
Patent EP-2333453-A1 (EP)
Inventor: BESCHI MOSE SILVANO
IPC: F24J2/52
Filed: 2010-10-08
Abstract: This invention concerns a device for positioning and fastening of solar panels on respective supporting framework on roofs or on the ground. Every supporting framework has supporting bars (14,15) for supporting the panels provided frontally with coupler slots (16). The device has a body (17) that has pairs of anchoring hooks (20) designed to engage with the slots (16) and which is associated with a prismatic block (22) which defines two supporting planes (23,23') on contiguous sides for supporting two parallel panels and it is provided with means (29,30) for blocking said panels on said supporting planes.
Patent EP-2387679-A1 (EP)
Title: Support amélioré de suspension de tuyau
Inventor: BENNE LEONARD THEODOOR
IPC: F16L3/10
Filed: 2010-01-15
Abstract: La présente invention porte sur un support (10) comprenant un corps (14) pour recevoir le tuyau et une partie de suspension (16) reliée au corps pour suspendre un tuyau à partir d'un profil (12) de plusieurs manières différentes, la partie de suspension comprenant : une partie recouverte (18) comportant une partie de pont (22) et deux parties de jambes (20, 21), la partie de pont s'étendant entre les deux parties de jambes et comprenant au moins une section d'appui (49) qui est construite pour reposer sur une surface supérieure du profil et les parties de jambes étant construites pour s'étendre de chaque côté du profil, la partie recouverte étant configurée pour s'ajuster sensiblement sur le profil afin de suspendre le tuyau à partir du profil d'une première manière, et une saillie (45) formée sur la partie de pont, la saillie étant formée pour s'ajuster sensiblement dans une fente qui est formée dans un côté inférieur du profil par deux arêtes du profil afin de suspendre le tuyau d'une autre manière, et un trou (50) formé dans la partie de pont, le trou étant configuré pour suspendre le support de suspension de tuyau à partir du profil par le biais d'une tige de suspension (52) pour suspendre le tuyau d'encore une autre manière.
Patent EP-2392151-A1 (EP)
Inventor: LEMARQUAND GUY
IPC: H04R9/04
Filed: 2010-01-27
Abstract: La présente invention concerne un équipage mobile (1) pour transducteur électrodynamique,, comprenant au moins un mandrin (2) support d'enroulement d'au moins un fil (3) bobiné, caractérisé par le fait que ledit mandrin (2) comprend au moins un premier élément (4) solidaire intérieurement d'au moins un second élément (5) de guidage de l'équipage mobile (1) au sein dudit transducteur, ledit premier élément (4) constituant, d'une part, un support d'enroulement dudit fil bobiné (3) de sorte que le bobinage se situe à l'intérieur dudit mandrin (2) et, d'autre part, des moyens d'émission de vibrations, tel un diaphragme, lesdites vibrations étant générées par le déplacement du bobinage induit par le passage du courant à l'intérieur du fil bobiné (3). L'invention concerne aussi un transducteur électrodynamique équipé d'un tel équipage mobile (1).
Patent EP-2430345-A1 (EP)
Inventor: MOENCH JOCHEN
IPC: F16K31/04
Filed: 2010-04-15
Abstract: The invention relates to a control valve (1) for a cooling circuit of an internal combustion engine, comprising a two-part valve housing having at least one flange region, wherein a second valve housing part (13) is designed to be integral, and the second valve housing part (13) comprises a rotor (31), wherein the rotor (31) comprises a first region having a worm gear (24) and a second region having a laminated core (10) on a rotor shaft (16), wherein two radial bearing elements (7, 30) are arranged on the rotor (31) and two axial bearing elements (4, 29) are arranged at the two ends of the rotor shaft (16), wherein the first axial bearing element (4) is arranged in a first valve housing part (5) and the second axial bearing element (29) and the two radial bearing elements (7, 30) are arranged in the second valve housing part (13).
Patent EP-2421858-A1 (EP)
Inventor: GIWERCMAN BIRGIT KJAELDGAARD
IPC: C07D409/06
Filed: 2010-04-20
Abstract: The present invention is directed to certain thioxanthene derivatives and phenothiazine derivatives suitable for use as anti-infective agents, in particular, for the treatment of infectious diseases. The invention furthermore relates to compositions comprising said anti-infective agents.
Patent EP-2454745-A1 (EP)
Title: Procédés de préparation d'une électrode
Inventor: HINTZ MICHAEL B
IPC: H01G9/008
Filed: 2010-04-14
Abstract: L'invention porte sur des procédés de préparation d'une électrode. Un fil de connexion métallique est prétraité pour faciliter la liaison du fil de connexion à une poudre métallique au cours d'une opération ultérieure de frittage par désoxydation. Une région de connexion peut être formée par mise en contact direct du fil de connexion métallique avec un métal réactif vis-à-vis des liquides. Après élimination des oxydes obtenus, une poudre métallique additionnelle peut subir un frittage par désoxydation sur la région de connexion pour former l'électrode. Les oxydes formés pendant le frittage par désoxydation sont ensuite retirés de l'électrode.
Patent EP-2419269-A1 (EP)
Title: Cellular panel
Inventor: DESJOYAUX BERTRAND
IPC: B32B3/12
Filed: 2010-03-18
Abstract: The present invention relates to a cellular panel deployable from a compacted form to a deployed form, including, in the compacted form thereof, a plurality of consecutive sheets substantially parallel to one another and substantially perpendicular to an expansion direction, each sheet being discretely joined at a plurality of junction points with the following and/or preceding sheet, the junction points being substantially regularly spaced apart along the lines substantially parallel to the sheets and alternating with the preceding and/or following junction points, characterized in that, on at least one line parallel to the expansion direction, one or more junction points are excised or are not made and the portions of the sheets associated with said excised or unmade junction points are excised.
Patent EP-2417151-A1 (EP)
Title: Peptides cycliques a activite antiparasitaire
Inventor: WONG YUNG-SING
IPC: A61P33/02
Filed: 2010-04-06
Abstract: La présente invention concerne un procédé de préparation d'un peptide cyclique à activité antiparasitaire et à activité anti-cancer. L'invention concerne également ce peptide en tant qu'agent antiparasitaire, par exemple dans le traitement de la toxoplasmose et en tant qu'agent anti-cancer. L'invention concerne également l'utilisation de ce peptide cyclique pour traiter les organes  ex vivo  avant transplantation.
Patent EP-2442925-A1 (EP)
Title: Verfahren und vorrichtung zur prozessüberwachung und prozessregelung beim expandieren von uoe-rohren aus stahl
Inventor: MUELLER LARS
IPC: B21D5/01
Filed: 2010-05-12
Abstract: Die Erfindung betrifft ein Verfahren und eine Vorrichtung zur Durchfürung des Verfahrens, mit einem in ein Rohr einführbaren Expanderwerkzeug bestehend aus einem an einer Zugstange angeordneten Werkzeugkopf mit in radialer Richtung aufspreizbaren Segmenten und einer daran angeordneten und dem jeweiligen zu kalibrierenden Rohrdurchmesser in der radialen Lage anpassbaren Kopfrolle zur Abstützung des Expanderwerkzeugs auf dem Rohr und einer das zu kalibrierende Rohr abstützenden Unterstützungsrolle. Dabei ist vorgesehen, dass die Kopfrolle mit einer Messeinrichtung zur Aufnahme der während des Expandierens auf die Kopfrolle einwirkenden Stützkraft versehen ist. Ferner ist eine Auswerte- und Überwachungseinheit der Messwerte und eine Abweichung von vorgegebenen Toleranzschwellen anzeigenden Signaleinheit vorgesehen.
Patent EP-2430298-A1 (EP)
Inventor: SAINT-MARCOUX ANTOINE
IPC: F02D35/02
Filed: 2010-05-10
Abstract: System for estimating at least one output parameter (PSe) of an internal combustion engine (1) comprising at least one cylinder (2), one moving piston (3) driven by a crankshaft (5), means (20, 21) for measuring the temporal variations of the crank angle and of the internal pressure of said cylinder, a calculating means (23) for calculating a plurality of combustion parameters (Xi), such as internal cylinder pressures characteristic of the combustion, variations in the pressure inside the cylinder and engine strokes, from said crank angle measurements and internal cylinder pressures, and an estimating means (24) for estimating at least one engine output parameter (PSe) from said combustion parameters (Xi), the estimating means (24) estimating at least one engine output parameter (PSe) from a weighted sum of said combustion parameters (Xi).
Patent EP-2454346-A1 (EP)
Title: Procédé de modulation d une unité d alkylation par l acide fluorhydrique ou sulfurique et procédé de production d alkylats
Inventor: LIU ZHICHANG
IPC: C07C2/58
Filed: 2010-07-09
Abstract: Cette invention concerne un procédé de modulation dune unité dalkylation par lacide fluorhydrique ou sulfurique en une unité dalkylation liquide ionique, lunité dalkylation par lacide fluorhydrique ou sulfurique comprenant au moins : un réacteur dans lequel sont mis en contact le catalyseur et les hydrocarbures ; un séparateur qui sépare un effluent du réacteur en une phase catalytique et une phase dhydrocarbures comprenant des alkylats ; une colonne de fractionnement qui sépare la phase dhydrocarbures comprenant des alkylats en au moins un courant contenant des alkylats ; un système de recyclage de la phase catalytique qui recycle au moins une partie de la phase catalytique du séparateur au réacteur ; ledit procédé consistant à : adapter le système de recyclage de la phase catalytique en prévoyant un système dinjection dacide et/ou un système dinjection dhydrocarbures halogénés dans le système de recyclage du catalyseur. Linvention concerne par ailleurs un procédé de production dalkylats.
Patent EP-2456526-A1 (EP)
Title: Raccords libérables et interchangeables pour têtes et manches de club de golf à orientations multiples
Inventor: THOMAS JAMES S
IPC: A63B53/02
Filed: 2010-07-19
Abstract: L'invention porte sur des têtes (402) de club de golf, qui viennent en prise de façon libérable avec des manches (106), de telle sorte qu'elles peuvent être facilement interchangées et/ou de telle sorte que l'orientation du manche par rapport à la tête de club peut être facilement changée. Des ensembles pour relier la tête et le manche de club peuvent comprendre un adaptateur (202) de manche et un adaptateur (302) de tête. L'adaptateur de tête peut avoir une surface extérieure s'étendant le long d'un premier axe et un alésage ayant une forme en coupe transversale le long d'un deuxième axe configurée pour une fixation à un élément de manche. La deuxième extrémité de l'adaptateur de manche peut avoir une forme en coupe transversale de polygone régulier ou une forme en coupe transversale définie par des cannelures. L'adaptateur de tête comporte une première extrémité et une deuxième extrémité le long d'un premier axe et un alésage ayant soit la forme d'un polygone régulier, soit une forme en coupe transversale définie par des cannelures le long d'un deuxième axe, qui est conformé de façon à recevoir la deuxième extrémité de l'adaptateur de manche suivant une pluralité d'orientations.
Patent EP-2442990-A1 (EP)
Title: Kupplungsschloss für eine anhängerkupplung
Inventor: ALBERS INGO DR
IPC: B60D1/06
Filed: 2010-06-17
Abstract: Kupplungsschloss für eine Anhängerkupplung, mit einer Aufnahme (9), in die ein Kupplungsglied (6) eingesetzt oder einsetzbar ist, einer mit der Aufnahme (9) verbundenen Winkelmesseinrichtung (13, 19), mittels welcher eine Verdrehung der Aufnahme (9) relativ zu dem Kupplungsglied (6) um eine Drehachse (18) erfasst wird oder werden kann, und einem elastisch mit der Aufnahme (9) verbundenen, magnetischen Haftkörper (24), der magnetisch an dem Kupplungsglied (6) anhaftet oder anhaften kann und die Winkelmesseinrichtung (13, 19) betätigt oder betätigen kann.
Patent EP-2399896-A1 (EP)
Inventor: SHIMADA TERU
IPC: C09K19/18
Filed: 2010-01-27
Abstract: The invention provides a liquid crystal compound having general physical properties necessary for a liquid crystal compound, that is to say, stability to heat, light or the like, a small viscosity, a suitable value of refractive index anisotropy, a suitable value of dielectric anisotropy, steep characteristics electro-optic characteristics, a wide temperature range of a nematic phase and an excellent compatibility with other liquid crystal compounds, and a liquid crystal compounds especially having a wide temperature range of a nematic phase. 
     A compound represented by formula (1).
     
For example, R 1  and R 2  are each independently alkyl having 1 to 9 carbons or alkenyl having 2 to 9 carbons, alkoxy having 1 to 8 carbons or alkenyloxy having 2 to 8 carbons; Q 1  and Q 4  are each independently fluorine or chlorine; Q 2  and Q 3  are each independently hydrogen, fluorine or chlorine, and one of Q 2  and Q 3  is hydrogen; Z is -CH 2 O or -COO-; and h is 1 or 2.
Patent EP-2445476-A1 (EP)
Inventor: VEILLET STANISLAS
IPC: A61Q17/04
Filed: 2010-06-25
Abstract: The invention relates to a food use of norbixin and an urucum extract enriched with bixin and/or norbixin. The invention also relates to a food composition including norbixin, bixin, or an extract including at least bixin or norbixin, said composition being for oral administration to protect the skin of mammals from UV rays.
Patent EP-2401910-A1 (EP)
Inventor: USLAR VALENZUELA WILLIAM RONNIE
IPC: A01J5/007
Filed: 2010-02-25
Abstract: A system that attached to mechanized milking equipment allows its automation that solves the subclinical mastitis by "differentiating" among each individual mammary quarter the time when teat cups must be removed after the milk is over, in an asynchronous and independent manner from other teat cups. Minimize the negative consequences of over-milking as a results of not removing teat cups on time after the milk flow has stopped; reduces economic, financial and productivity problems arisen as a result of subclinical mastitis mainly caused by over-milking; thus improving the product quality and amount. Mastitis produces somatic cells in milk, the greater the amount of these cells the lower the price received by the producer. Damage to the mammary gland may be permanent resulting in the loss of the gland and may be contagious. 
     The system includes teat cups, tubes, collector, discrete flow sensor, vacuum sensor, command control, software comprising as a part thereof the mammary quarters with physiological and anatomical characteristics thereof.
Patent EP-2483895-A1 (EP)
Title: Verfahren zum aufbringen von kunststoff auf einzelleiter und hts-verbund hergestellt aus den einzelleitern
Inventor: ARNDT TABEA
IPC: H01B13/18
Filed: 2010-09-29
Abstract: Die vorliegende Erfindung bezieht sich auf ein Verfahren zum Aufbringen eines Kunststoffes auf wenigstens einen Einzelleiter (10) eines Hochtemperatur-Supraleiters (HTS)-Verbundes nach Art eines Roebel-Leiters. Weiterhin wird ein Hochtemperatur-Supraleiter (HTS)-Verbund angegeben, hergestellt mit dem Verfahren. Der wenigstens eine Einzelleiter (10) umfasst wenigstens einen Träger (11) und wenigstens eine supraleitende Schicht. Es werden Partikel (12) auf den Einzelleiter aufgebracht (2, 6). Darauf folgend wird eine thermische Behandlung (3, 7, 8) durchgeführt, welche zu einem teilweisen oder vollständigen Aufschmelzen der Partikel (12) und nach Ankühlung zu einer Kunststoff Schicht (13) auf dem Einzelleiter (10) führt.