baber/WOPTO huggingface dataset:
Patent JP-2010136253-A (JP)
Title: Imaging apparatus and control method thereof
Inventor: CHOKAI HIROSHI
IPC: H04N5/372
Filed: 2008-12-08
Abstract: <P>PROBLEM TO BE SOLVED: To provide an imaging apparatus for facilitating a phase adjustment in switching of a frequency of a clock and making it difficult to visually recognize a pattern of beat noise.  <P>SOLUTION: A digital camera includes a CCD sensor 104, a multi-output clock generating circuit 110 for generating a plurality of clocks, a timing signal generating circuit 105, and a control section 121. In accordance with a reference timing clock MCLK generated by the multi-output clock generating circuit 110, the timing signal generating circuit 105 generates a plurality of timing signals for controlling operation of the CCD sensor 104. Synchronously with a vertical synchronizing signal generated by the timing signal generating circuit 105, the control section 121 switches a frequency of the reference timing clock MCLK generated by the multi-output clock generating circuit 110 to a corresponding frequency among a plurality of preset different frequencies.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010137301-A (JP)
Title: Continuous sheet feeder
Inventor: TAKAHASHI SHUNEI
IPC: B26D1/34
Filed: 2008-12-09
Abstract: <P>PROBLEM TO BE SOLVED: To cut a thick and hard continuous sheet even with a small air cylinder device by increasing the cutting speed of a cutting blade for cutting the continuous sheet.  <P>SOLUTION: This continuous sheet feeder is equipped with: two rolls 3, 4 for pre-feeding and post-feeding which deliver the downstream side and upstream side of the continuous sheet (a), respectively, and which are arranged parallel to each other; a nip roller 12 for pressing the continuous sheet against the peripheral surface of the roll 4 for post-feeding which runs from the roll 3 for pre-feeding near the roll 4 for post-feeding; the cutting blade 13 for cutting the continuous sheet pressed against the nip roller 4; and a rotating arm 15 which holds the cutting blade 13 and rotates when the cutting blade cuts the continuous sheet. The air cylinder device 16 which quickly operates the portions starting from a piston rod 16a to the rotating arm, by storing and accumulating air in one cylinder chamber and releasing the other cylinder chamber to the atmosphere when the continuous sheet is cut, is provided as a means for driving the rotating arm. A trigger 28 is also provided to arrest the rotating arm at the standby position until the continuous sheet is cut.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2009221645-A (JP)
Title: Fiber having modified cross section, and makeup cosmetic
Inventor: MATSUMOTO SHOJI
IPC: A61Q1/00
Filed: 2008-12-10
Abstract: <P>PROBLEM TO BE SOLVED: To provide a fiber having modified cross section giving excellent light dispersion and reflection actions and skin feeling with glossy appearance when added into cosmetics and applied, and at the same time, having smooth use feeling without feeling of a foreign body, in addition, volume-up effects when used as mascara, and makeup cosmetics containing the fiber having the modified cross section.  <P>SOLUTION: The fiber having modified cross section has a cross section of a filament vertically cut to the longitudinal fiber axis exhibiting a shape in which two circles having openings are connected at least one point. In the fiber, the openings of two circles are connected without being blocked, the maximum length connecting optional two points in a cross sectional shape is ≥1.1 times of the diameter of a circle having the maximum diameter, the maximum length is 5-100 μm, both two circles have each 30-140° angle of opening, and monofilament fineness is 1.0-7.0 dtex.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2009118494-A (JP)
Title: Wireless repeater
Inventor: KURITA MASANORI
IPC: H04B7/212
Filed: 2008-12-15
Abstract: <P>PROBLEM TO BE SOLVED: To provide a wireless repeater capable of increasing the number of storable lines per wireless repeater or a communication speed by reducing reception sensitivity suppression to one radio section by unwanted emission generated by the other.  <P>SOLUTION: The wireless repeater 1 receives radio waves transmitted from a base station or a terminal by an antenna 5A for the base station or an antenna 5B for the terminal, and then transmits the reception signal to the terminal or the base station from the antenna 5B for the terminal or that 5A for the base station. When the duty factor of a slot is not more than 50%, change-over switches 28A, 28B are driven to use the omnidirectional antennas 5A, 5B as antenna devices. When the duty factor of a slot exceeds 50%, the change-over switches 28A, 28B are driven to use the antenna device comprising the antennas 5A, 5B having coaxial cables 6A, 6B.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2010142322-A (JP)
Title: Dishwasher/dryer
Inventor: NIWA TAKASHI
IPC: A47L15/42
Filed: 2008-12-17
Abstract: <P>PROBLEM TO BE SOLVED: To provide a highly reliable dishwasher which is high in reliability and has a reduced number of cables for signal transmission.  <P>SOLUTION: Signals from a switch operation portion 7 are converted to serial signals by a microcomputer 10 which is an input signal processing portion and transmitted from a serial output terminal 10f through a serial signal transmission path portion 11 to a control box 12. From the control box 12, driving signals are transmitted to a controlled device according to the transmitted signals. By the configuration, cables are reduced and the reliability of signal transmission is improved.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010142837-A (JP)
Title: Laser processing method
Inventor: YAMAZAKI YUTAKA
IPC: B23K26/00
Filed: 2008-12-18
Abstract: <P>PROBLEM TO BE SOLVED: To improve uniformity of cross sectional shape of a cavity formed inside a work piece at respective depth positions which mean different distance from the surface of the work.  <P>SOLUTION: Aberration of a convergence lens 12 is adjusted so that the length of the laser beam 14 in the optical axis 15 direction stays constant in the convergence region of a laser beam 14. Herein, the convergence region means the region where energy density has reached to a level capable of generating a reformed region 19 inside the work 1 by the convergence of the laser beam 14. In this way, the reformed region 19 can be formed in which the laser beam 14 has the same length in the optical axis 15 direction. Thus, at positions of a plurality of depth, that is, at positions of different distance from the surface of the work 1, cavities 2 with a constant width can be formed on a plurality of scheduled work lines 3a-3e extending in the perpendicular direction to the optical axis 15 of the laser beam 14.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010142399-A (JP)
Title: Ultrasonic diagnostic apparatus
Inventor: KOYABU KAZUYA
IPC: A61B8/00
Filed: 2008-12-18
Abstract: <P>PROBLEM TO BE SOLVED: To provide an ultrasonic diagnostic apparatus with improved operability, capable of achieving the cost reduction, miniaturization, waterproofness and expandability.  <P>SOLUTION: The ultrasonic diagnostic apparatus includes: an ultrasonic probe 51 for transmitting/receiving ultrasonic waves; a monitor 50 in which an ultrasonic image based on the ultrasonic waves is displayed; a touch panel 1 which senses the pressed position on the surface to output specified position information; a touch panel display control part 41 for displaying a plurality of operation content images 30a and 30b for controlling the operation in the touch panel 1; and a control signal creating part 42 for creating a control signal corresponding to the operation content image 30a or 30b selected from the plurality of operation content images 30a and 30b based on the specified position information from the touch panel 1. The ultrasonic diagnostic apparatus displays an ultrasonic image in the monitor 50 or controls an ultrasonic probe 44 based on the control signal. Recesses and projections 11 and 12 are formed on the surface of the touch panel 1 for discriminating the display positions of the plurality of operation content images 30a and 30b.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2009110653-A (JP)
Title: Method for optical disk recording, optical disk device, and optical disk
Inventor: FUJITA SHINJI
IPC: G11B7/125
Filed: 2008-12-19
Abstract: <P>PROBLEM TO BE SOLVED: To provide a method for optical disk recording and an optical disk device where precise compensation is possible without changing a basic waveform in downward compatibility when an optical disk compatible with a high linear velocity is recorded at low speed, with respect to various kinds of optical disks whose recording film materials or recording mechanisms are different from each other, and to provide an optical disk facilitating a compensation operation.  <P>SOLUTION: In the method for optical disk recording, a recording waveform is converted into a multi-pulse waveform, the rising and falling timings of a leading pulse (pulse width) are independently varied according to a front space length and a recording mark, and the rising and falling timings of a final pulse (pulse width) are varied according to a back space length and the recording mark independently or in a fixed relation. For a minimum mark for recording with a single pulse, the rising timing is varied according to the front space length and the recording mark, and the falling timing (pulse width) is varied according to the back space length and the recording mark.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2009148260-A (JP)
Title: Covering apparatus of tobacco processing industrial machine
Inventor: GROTHAUS FRANK
IPC: A24C5/20
Filed: 2008-12-19
Abstract: <P>PROBLEM TO BE SOLVED: To improve conveyance of a covering paper strip in a covering apparatus.  <P>SOLUTION: The present invention relates to a covering apparatus of a tobacco processing industrial machine, particularly a filter attaching machine in which a covering paper strip (10) is linearly, especially horizontally conveyed to a conveyer part (FA) and conveyed through two parallel matched rotatable turning rolls (22 and 24) to the inlet side of the conveyer part (FA) and the outlet side of the conveyer part (FA). The covering apparatus is characterized in that an inlet-side turning roll (22) in a linear conveyer part (FA) and an outlet-side turning roll (24) can mutually simultaneously be turned or are turned around a turning axis line (16) vertically formed on rotating axial lines (23 and 25) of turning rolls (22 and 24).  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent JP-2010144659-A (JP)
Title: Vaporizing device for liquefied fuel vehicle
Inventor: SASAOKA SHINICHI
IPC: F01N5/02
Filed: 2008-12-19
Abstract: <P>PROBLEM TO BE SOLVED: To provide a vaporizing device for liquefied fuel suppressing power consumption of an engine and increase of a vehicle weight and improving fuel economy of a vehicle with the vaporizing device installed.  <P>SOLUTION: The vaporizing device includes a vaporizer 12 vaporizing the liquefied fuel by exchanging heat between the liquefied fuel and heating medium, an exhaust introduction passage 16 branched from an exhaust passage 30 of the engine and introducing a part of exhaust gas of the engine as the heating medium into the vaporizer 12, a valve 17 provided in the exhaust introduction passage 16 and adjusting an amount of the exhaust gas introduced into the vaporizer 12, a temperature sensor 41 detecting temperature of vaporized fuel, and a control unit 20 controlling the temperature of the vaporized fuel by adjusting an opening degree of the valve 17 based on the detected temperature of the vaporized fuel.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010152962-A (JP)
Title: Semiconductor memory device
Inventor: IWAI TAKAYUKI
IPC: G11C11/4074
Filed: 2008-12-24
Abstract: <P>PROBLEM TO BE SOLVED: To provide a semiconductor memory device of which the operational margin is improved by changing over a storage capacity according to a power source voltage or an external control signal.  <P>SOLUTION: The semiconductor memory device comprises: a memory cell array including a plurality of word lines, a plurality of bit lines intersecting the plurality of the word lines, and a plurality of binary-data holding memory cells arranged at each intersection of these word lines and bit lines; and a control circuit for changing over the storage capacity of the memory cell array and changing the address space required for an access to the memory cell based on the control signal.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010152805-A (JP)
Title: Object image identification system, method of controlling operation thereof, and operation control program therefor
Inventor: HAYASHI DAISUKE
IPC: G06T7/00
Filed: 2008-12-26
Abstract: <P>PROBLEM TO BE SOLVED: To prevent a face image from becoming undetectable even though the face image exists in a portion where the face image is highly likely to exist.  <P>SOLUTION: A plurality of face image identification devices 11 to 1N, which, if scores obtained by making the features of an image into scores are not lower than a first threshold value, determine the image to be a face image, are connected in cascade to a group of face image identification devices 10. The image that consists of a number of frames like animation is input frame by frame to the group of face image identification devices 10; if the face image is contained in one frame of a subject image, the face image is detected. For the next and subsequent subject images, if face image detection is carried out in an area corresponding to an area around the face image detected, a face image detection process is performed using a second threshold value that is lower than the first threshold value.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010155739-A (JP)
Title: Ultra-light mortar
Inventor: NAKAJIMA YUTAKA
IPC: C04B28/14
Filed: 2008-12-26
Abstract: <P>PROBLEM TO BE SOLVED: To provide ultra-light mortar capable of exerting high initial strength without causing material separation or swelling/deformation mainly in lower parts of a placed structure, even when placed in a space that is extremely long in the height direction, and is capable of suppressing decrease in initial strength without causing material separation or swelling/deformation mainly in lower parts of a placed structure, even when placed or constructed under low-temperature conditions.  <P>SOLUTION: The ultra-light mortar comprises: a binder comprising at least portland cement, calcium aluminate and anhydrous gypsum; and ultra-lightweight aggregate with density <0.3 kg/L. Here, the binder has a maximum grain size of ≤80 μm and an average grain size of ≤10 μm, and the ultra-lightweight aggregate has a maximum grains size of ≤1 mm.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2010157623-A (JP)
Title: Electronic component mounting device and electronic component mounting method
Inventor: OYAMA KAZUYOSHI
IPC: H05K13/08
Filed: 2008-12-26
Abstract: <P>PROBLEM TO BE SOLVED: To facilitate an operation to replace a component supply device when the type of a printed board is changed.  <P>SOLUTION: When no suction-object component supply unit 13 is set so far and a component supply unit 13 is newly attached by replacement, a CPU 16 determines that automatic initial positioning processing is necessary, and a tape is fed by one pitch based upon the imaging result of a pocket by a substrate recognition camera 14 until a pocket containing an electronic component reaches a component taking-out opening, so that the electronic component is automatically and initially positioned.  <P>COPYRIGHT: (C)2010,JPO&INPIT
Patent JP-2008533706-A (JP)
IPC: H01F38/14
Filed: 2006-02-22
Abstract: The transformer has stator- and rotor-sided coupling coils (80`, 80``, 82`, 82``) for inductive data transmission and assigned to each other in pairs. The coils are attached to transmitting and/or receiving electronic circuits and separated from an area of energy coils (76, 78) by parts of respective core sections (72, 74). The coils are arranged in an associated stator- and rotor part under formation of a spatially curved loop.
Patent JP-2008533011-A (JP)
Title: 治療薬としての置換ガンマラクタム
IPC: A61K31/402
Filed: 2006-03-06
Abstract: 本明細書において、式：     で示される化合物またはその医薬的に許容しうる塩、プロドラッグもしくは代謝物を開示する。Y、AおよびBは、明細書の記載と同意義である。これらの化合物に関する方法、組成物および中間体も開示する。
Patent JP-2008533844-A (JP)
Title: ビデオ・レート制御における状況適応帯域幅調節
IPC: H04N7/26
Filed: 2006-03-10
Abstract: 【課題】ビデオ・レート制御の際の状況適応帯域幅調節。 【解決手段】方法及び装置は、目標ビット・レートでビデオを符号化し、そしてさらに比較的一貫した映像品質で複雑さが変化するビデオを符号化するために量子化パラメータ（ＱＰ）の変化を許容する。一定ビット・レート（ＣＢＲ）符号化は、伝送環境又は同報通信環境におけるような、複数のアプリケーションにおいて望ましい。しかしながら、従来のＣＢＲ技術は、映像品質を損なう。開示された技術は、ＱＰ値の適応変化を許容し、そしてＣＢＲ環境に適用可能である目標ビット・レートへの十分な追従を維持しつつ、可変ビット・レート（ＶＢＲ）方式において適用可能な映像符号化の改善を提供する。 【選択図】図３
Patent JP-2008533845-A (JP)
IPC: H04N19/89
Filed: 2006-03-10
Abstract: A method and apparatus of processing a multimedia frame comprising a first section received in error are disclosed. The method comprises obtaining temporal prediction data corresponding to a first reference frame. The method further comprises determining whether the first reference frame is reliable for estimating the first section. The method further comprises estimating the first section received in error based on one or more sections other than the first section of the multimedia frame and the first reference frame, if it is determined that the first reference frame is reliable.
Patent JP-2008532785-A (JP)
Title: 回転マシンを装填するための工具保持用のチャック
IPC: B23B31/12
Filed: 2006-03-16
Abstract: 本発明は、工具をクランプ留めするように前方に収束し、かつ並進的に案内される幾つかのジョー（７）が中に取着された本体（２）を有するマンドレルに関する。各ジョー（７）は、矩形の断面を有し、これと相補的な外形が本体に形成された溝部中で案内される。各ジョー（７）は、ジョーの内面（１０）が、マンドレルの軸線と同軸の円（１２）に対して実質的に正接をなしている面内に位置されるように配向され、各ジョー（７）は、ジョーの内面（１０）の長手方向に延びる中央平面（Ｐ）が、マンドレルの軸線と同軸であり、かつ工具のシャンクを表す円（１２）の接触ラインに対してずれるように、本体中に位置されている。このため、前記円との接触は、動作エッジとして称されるエッジ（１３）に果たされ、このエッジは、工具のクランプ留め方向において、円の前方、若しくは、円に対して正接をなすように位置されている。
Patent JP-2008532815-A (JP)
Title: 表面構造を持つ部品を製造する方法、セラミック部品、及び、その方法の用途
IPC: B28B1/26
Filed: 2006-03-10
Abstract: 【課題】表面の品質がより高い部品の製造を可能にすること。 【解決手段】液状媒体内の、焼結し易い粒子のサスペンションを設けるステップと、表面構造（４）の少なくとも一部のネガインプリントが設けられた有形表面（７）を有するスタンプ要素（２）を設けるステップと、レセプタクル（５）を含むモールド（１）を設けるステップと、前記レセプタクル（５）内に所定量のサスペンション（６）を導入するステップと、前記レセプタクル内の前記サスペンションに前記スタンプ要素（２）の前記有形表面（７）を当接するステップとを備える、前記表面構造（４）有する部品を製造する方法である。前記モールドの前記レセプタクルは、少なくとも１つの多孔性壁（８、９）を有し、前記多孔性壁（８、９）を通して前記液状媒体の少なくとも一部を排出する間、前記スタンプ要素（２）の前記有形表面（７）を当接する。 【選択図】図１Ａ
Patent JP-2008534266-A (JP)
Title: 触媒回収を伴う改善されたポリマーハロゲン化方法
IPC: B01J27/32
Filed: 2006-03-24
Abstract: 本発明は、ハロゲン化アンチモン触媒の存在においてスチレン系ポリマーを臭素化する方法に関する。本発明は、更に、不溶性固体の形成が減少された、アンチモン触媒を回収する方法に関する。
Patent JP-2008534154-A (JP)
Title: 血管アクセス
IPC: A61M25/00
Filed: 2006-03-30
Abstract: 装置が、中空針、針へと同軸に取り付けられる拡張器、および拡張器へと同軸に取り付けられる鞘を含むことができる。拡張器は、鞘に対してスライドして変位可能であってよい。
Patent JP-2008536003-A (JP)
Title: Ｍｃｒ含有量の少ない原油生成物の製造方法及び触媒
IPC: C10G45/08
Filed: 2006-04-07
Abstract: 【課題】不利な原油を、輸送及び処理設備での処理に適するよう一層望ましい特性を有する原油生成物に転化するか、或いは不利な原油の他の特性への変化を最小限にしながら、不利な原油の選択された特性を変化できる経済的かつ技術的なシステム、方法、及び／又は触媒を提供する。 【解決手段】原油原料を１種以上の触媒と接触させて原油生成物を含む全生成物を製造する方法。原油生成物は２５℃、０．１０１ＭＰａにおいて液体混合物である。原油生成物のＭＣＲ含有量は原油原料のＭＣＲ含有量の９０％以下である。原油生成物の他の１つ以上の特性を原油原料のそれぞれの特性に比べて１０％以上変化できる。 【選択図】図１
Patent JP-2008538754-A (JP)
Title: 薬剤を含んだ所定のレイヤパターンを有する複層構造体
IPC: A61K9/70
Filed: 2006-04-11
Abstract: 【課題】制御された治療を改善する、微細加工された所定の空間的パターンを有するポリマからなる複層構造体を提供する。 【解決手段】微細加工された概ね予め定められた幾何学的構成をなす空間的パターン（貯蔵室及びチャネルなど）を有するポリマからなる複層構造体を提供する。本発明によって提供される幾何学的なパターンは、パターンの制御を向上させたものであり、制御された治療の改善を可能にする。好適な実施態様では、本発明のポリマ複層構造体は、生分解可能であり、その生体内での寿命は、供給する薬の持続時間よりも長い。したがって、ポリマ構造体の幾何学的なパターンは、治療中にその形状が著しく変化することなく治療薬の送達を制御し、その構造体は、治療薬がなくなった後に分解する。この方法では、治療薬の分解副産物による干渉が最小限になり、治療薬の送達は、分解の進行具合に依存しない。 【選択図】図４ａ
Patent JP-2008538451-A (JP)
Title: 細い導電線を有する光学コーティング
IPC: G09F9/00
Filed: 2006-04-14
Abstract: 目標とする光学的性質及び目標とする電気的性質の組合せを達成するために，伝導性のマイクロトレース（６４）が，コーティングされた又はコーティングされていない基板（２８）上に形成される。コーティングされた基板に関して，コーティング（１００）は，前記伝導性のマイクロトレースの前又は後に形成されてもよい。前記コーティングは，ＩＲフィルタ，又は反射光及び色ずれの減少を提供するように設計されればよく，前記伝導性のマイクロトレースは，ＥＭＩ遮蔽のため又はヒーターとして使用する場合のように導電性を提供するために用いればよい。他の実施態様では，高い可視光透過率を維持しつつも，前記伝導性のマイクロトレースがそれらの意図する目的を達成することができるように，コーティングされていない可撓性のある透明な基板上に前記伝導性のマイクロトレースが構成されており，２５ミクロン未満の幅を有する。前記伝導性のマイクロトレースは，電気めっき法の使用又はインクジェット印刷法を用いるような様々な方法を用いて形成すればよい。
Patent JP-2008539815-A (JP)
IPC: A61B18/12
Filed: 2006-04-28
Abstract: Forceps for performing endoscopic or arthroscopic surgery include a body assembly, a tube assembly, and a pair of handles that pivot with respect to the body. The tube assembly is removably attached to the body assembly. The tube assembly includes a hollow tube and a tip assembly. The tip assembly includes an electrode or a blade for performing the surgery. The tip assembly and the blade are connected to the body and the handles by a cable. As the handles pivot, the cable slides within the tube to move the blade. When a different tube assembly (i.e., a bipolar or a monopolar electrode) or another style of tip assembly are desired, the installed one is removed and replaced by a new tube assembly or tip assembly as desired.
Patent JP-2008546439-A (JP)
IPC: B26B19/38
Filed: 2006-06-06
Abstract: A cartridge for an appliance for personal care, such as skin, dental or hair treatment includes a main body, a dispensing structure for dispensing a substance, such as a liquid, a paste or a gel, and a cartridge detachably connected to the main body. The cartridge bounds a reservoir space for holding the substance to be dispensed and includes a flexible wall part bounding the reservoir space for allowing reservoir space volume to accommodate to a volume of the substance filled therein and volumes of the substance dispensed therefrom; a rigid wall part also bounding the reservoir space, and a rigid housing. The flexible wall part is connected to the rigid housing along a contour of the rigid wall part.
Patent JP-2008546918-A (JP)
Title: 流体ジェット切断方法
IPC: D06M15/11
Filed: 2006-06-14
Abstract: 無機繊維材料物品のような繊維材料のための流体ジェット切断方法を提供する。流体ジェット切断方法に用いるための流体組成物も、提供する。切断流体組成物は、キャリア流体および繊維材料の切断面のためのコーティング組成物を含有する。繊維材料の流体ジェット切断方法を実施するための装置も、提供する。 【選択図】図２Ｃ
Patent JP-2009501143-A (JP)
IPC: C07B61/00
Filed: 2006-06-12
Abstract: This invention provides an improved process for preparing cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-2-methoxy-5,6,7,8-tetrahydronaphthalene hydrochloride which is an intermediate for the preparation of (−)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydronaphthalene-2-ol which is useful for the treatment of osteoporosis.
Patent JP-2008543960-A (JP)
Title: アリールアミン、アリールエーテルおよびアリールチオエーテルの製造方法
IPC: C07C255/58
Filed: 2006-06-14
Abstract: 本発明は、第１級または第２級アミン、アルコールまたはチオアルコール(II)を、ブレンステッド塩基の存在下で、かつａ）Ｖ、Ｍｎ、Ｆｅ、Ｃｏ、Ｎｉ、Ｒｈ、Ｐｄ、Ｉｒ、Ｐｔの群から選択された遷移金属、該遷移金属の錯体、塩または化合物、およびｂ）少なくとも一種のスルホン化されたホスフィン配位子を含む触媒または予備触媒の存在下で、置換されたアリールまたはヘテロアリール化合物(I)と、溶剤または溶剤混合物中でスキーム１にしたがって、クロス−カップリングさせることにより、アリール−またはヘテロアリールアミン、エーテルまたはチオエーテル(III)を製造する方法に関する。スキーム１中、Ｈａｌはフッ素、塩素、臭素、ヨウ素、アルコキシ、トリフルオロメタンスルホネート、ノナフルオロトリメチル−メタンスルホネート、メタンスルホネート、４−トルエンスルホネート、ベンゼンスルホネート、２−ナフタレンスルホネート、３−ニトロベンゼンスルホネート、４−ニトロベンゼンスルホネート、４−クロロベンゼンスルホネート、２，４，６−トリイソプロピルベンゼンスルホネートまたは他のいずれかのスルホネートを表し、ＸはＯ、Ｓ、またはＮＲ”を表す。本発明は、新規なホスフィン配位子にも関する。
Patent JP-2009501549-A (JP)
Title: ヒト抗ｂ７ｒｐ１中和抗体
IPC: A61P37/02
Filed: 2006-07-18
Abstract: 本発明は、ヒトＢ７関連タンパク質−１（Ｂ７ＲＰ１）と相互作用するかまたはこれに結合する抗体、およびＢ７ＲＰ１に結合し、これによってＢ７ＲＰ１の機能を中和する抗体を提供する。本発明はまた、前記抗体の医薬組成物、およびＢ７ＲＰ１機能を中和する方法、特に、医薬的に有効な量の抗Ｂ７ＲＰ１抗体を投与することによって免疫障害（例えば、不適切な免疫応答）を治療する方法を提供する。抗Ｂ７ＲＰ１抗体を用いて試料中のＢ７ＲＰ１の量を検出する方法もまた提供される。