baber/WOPTO huggingface dataset:
Patent DE-69024758-D1 (DE)
Inventor: FERRONE SOLDANO
IPC: C12N5/10
Filed: 1990-11-08
Granted: 1996-02-22
Abstract: The invention concerns murine antiidiotypic monoclonal antibodies which are the internal image of determinants recognized by a monoclonal antibody on high molecular weight-melanoma associated antigen (HMW-MAA), antibody derivatives, hybridoma cell lines secreting such antiidiotypic monoclonal antibodies, and processes for the preparation of such antiidiotypic monoclonal antibodies, of their derivatives and of the hybridoma cell lines. The murine antiidiotypic monoclonal antibodies are useful for the determination of antibodies directed against high molecular weight-melanoma associated antigen, for the modulation of the immune response to HMW-MAA and for the treatment of melanoma.
Patent DE-69029294-D1 (DE)
Inventor: SEED BRIAN
IPC: C12N15/13
Filed: 1990-08-18
Granted: 1997-01-16
Abstract: The invention relates to substantially pure non-human primate CD4, and fragments thereof which bind to HIV or SIV gp120. The invention also relates to gp120 binding molecules related to human CD4 but which may exist in glycosylated form. The invention also relates to fusion proteins which comprise the CD4 molecules of the invention, or fragments thereof, and an immunoglobulin light or heavy chain, wherein the variable region of the light or heavy chain has been replaced with CD4 or fragment thereof which is capable of binding to gp120. The invention also relates to fusion proteins comprising the CD4 molecules of the invention and a cytotoxic polypeptide. The invention also relates to an immunoglobulin-like molecules comprising the fusion proteins of the invention together with an immunoglobulin light or heavy chain. The invention also relates to methods of treating HIV or SIV infection comprising administering the CD4 molecules of the invention, glycoproteins, fragments thereof, fusion proteins or immunoglobulin-like molecules of the invention to an animal. The invention also relates to assays for HIV or SIV comprising contacting a sample suspected of containing HIV or SIV gp120 with the CD4 molecules of the invention, fragments thereof, glycoproteins, immunoglobulin-like molecules, or fusion proteins of the invention, and detecting whether a complex is formed. The invention also relates to nucleic acid molecules which specify the proteins, glycoproteins and fusion proteins of the invention as weil as vectors and transformed hosts.
Patent DE-69101703-D1 (DE)
Inventor: HASTINGS OTIS H
IPC: B32B7/025
Filed: 1991-01-24
Granted: 1994-05-19
Abstract: A laminate coating comprising a durable outer ply which is resistant to abrasion and impermeable to water, bonded to and through a conductive layer of fibers and an integrally enveloping adhesive layer which is disposed on a vehicle component surface, such that the laminate coating upon curing is bonded to the vehicle component surface such as the surface of an aircraft part especially the fuselage, wing parts or tail section. The conductive layer is connected to a source of electrical energy and control means adapted to control the temperature of the coated surface of the aircraft part.
Patent DE-69102657-D1 (DE)
Inventor: MCMARLIN ROBERT M
IPC: E04C1/42
Filed: 1991-01-11
Granted: 1994-08-04
Abstract: A glass block wall (10) has a frame member (12) that frictionally engages the glass block (14) adjacent thereto. A continuous flexible spacer member (16) extends along the horizontal end walls of the glass blocks in each course. Separate vertical spacer members (46) abut the adjacent vertical end walls of the glass blocks and a filler material is (18) positioned in the recess formed between the edges of the adjacent glass blocks (14) and the edge of the spacer member (16). The spacer members (16) have a configuration to align the glass blocks (14) in the wall and to stabilize each of the glass blocks in the wall.
Patent DE-69103036-D1 (DE)
Inventor: SOHNER HAROLD K
IPC: H04B3/38
Filed: 1991-01-09
Granted: 1994-09-01
Abstract: A regenerative RF bi-directional communications system (10) is provided for establishing RF coverage within a RF block tunnel area (12). The system uses a plurality of cascaded amplifier stages (18) for periodically regenerating signals which are transmitted and received along a series of radiating cable length (16) which link base station transceivers (14) to hand-held or like mobile communication units. An intermediate frequency distribution system is used so that the required level of amplification is achieved through the several cascaded amplifier stages (18) at the level of low-power IF signals generated from the original RF signals in conjunction with the appropriate oscillator and pilot signals. The IF distribution system restricts the cascading effect occurring due to the plurality of cascaded amplifier stages on the relatively low-power IF signals, thereby producing a negligible amount of intermodulation. <IMAGE>
Patent DE-69108649-D1 (DE)
Inventor: MARILLET ROGER
IPC: A61C8/00
Filed: 1991-09-05
Granted: 1995-05-11
Abstract: The invention relates to an implant comprising a first monobloc component (3) of general cylindrical shape, which is made of a material of the carbon-carbon type and is threaded on the outside and intended to be screwed into a suitable cavity formed in a bone (1); and a second component (10) made of another material of greater hardness, comprising a part (14) designed to serve as a base for the securing of an article (15) intended to be connected rigidly to the bone; the first component (3) and the second component (10) having complementary shapes permitting screwing and allowing the second component to be locked in the first component. <IMAGE>
Patent DE-69112904-D1 (DE)
Inventor: WANG BOSCO SHANG
IPC: C07K16/00
Filed: 1991-04-22
Granted: 1995-10-19
Abstract: The present invention is directed to antibodies, in particular monoclonal antibodies, of porcine somatotropin (pST). When these antibodies are administered together with pST, the growth of vertebrates is greater than that achieved with the administration of pST alone. The invention is also directed to an increase in the growth of vertebrates which persists over long periods when an antibody to a somatotropin is administered together with such somatotropin.
Patent DE-69114476-D1 (DE)
Inventor: ORBAN ERNOE
IPC: A61K38/13
Filed: 1991-11-27
Granted: 1995-12-14
Abstract: The invention relates to a pharmaceutical composition for oral administration containing cyclosporin A and/or cyclosporin G as active ingredient, which possess advantageous absorption characteristics, and to a process for preparing this composition. The composition according to the invention comprises 1 part by mass of one or more cyclosporin(s) dissolved in 4 to 50 parts by volume of propylene glycol, 0 to 25 parts by volume of ethanol and 0.0 to 5 parts by mass of a polyoxyethylene/polyoxypropylene block polymer in homogenized state. Based on examinations carried out at 100 DEG  C., the stability of solutions prepared according to the invention does not differ from that of the commercially available Sandimmun oral solution.
Patent DE-69123940-D1 (DE)
Inventor: UETAKE AKIHIRO
IPC: H04N5/782
Filed: 1991-10-31
Granted: 1997-02-13
Abstract: A digital VTR is provided with a block segmenting circuit (5) for converting an input digital picture signal into data segmented into blocks of picture elements, an encoding circuit (8) for compressing and encoding the output data of the block segmenting circuit block-by-block, a channel encoding circuit (11) for channel encoding the encoded output data from the encoding circuit, an audio signal encoding circuit (15) for encoding an input digital audio signal, and an additional code generating circuit for generating an additional control code which includes subdata. The encoded picture data from the channel encoding circuit (11), the encoded audio data output from the audio signal encoding circuit (15), the additional control code and pilot signal data for tracking are recorded in skewed tracks (TA, TB) traced on a magnetic tape (78) by a magnetic head or heads (13A, 13B) mounted on a rotary drum (76), with each skewed track (TA, TB) having pilot signal data recorded at least adjacent the end portion of the track (TA, TB) at which the magnetic head (13A, 13B) enters into contact with such track (TA, TB), subdata recorded at the other end portion at which the magnetic head (13A, 13B) leaves the track (TA, TB), and the picture data and the audio data recorded at an intermediate portion of the track (TA, TB), so that both picture data and audio data can be reproduced with high quality while the subdata can be played back with relatively high accuracy. <IMAGE>
Patent DE-69208260-D1 (DE)
Inventor: ATKINS IAN PAUL
IPC: H02H3/07
Filed: 1992-09-22
Granted: 1996-03-21
Abstract: A module for insertion into a combined signal and power carrying line, especially into a CATV line, for protecting a system associated with the line from an overcurrent comprises: (i) a housing (50) having connection ports (51, 52) for cables (53, 54) forming the line and being impedance matched to the line, one of the conductors of the cables being connected together via a capacitor (23); and (ii) a solid-state overcurrent protection circuit that is connected across the capacitor via inductors (24, 25) to isolate it from the signal on the line, the protection circuit being capable of switching from a conducting to a blocking state in response to an overcurrent and being capable of resetting itself or attempting to reset itself into its conducting state one or more times after it has switched into its blocking state. If line containing  a number of such modules is subjected to an overcurrent, the protection device in the nearest module upstream will switch so that only that part of the line downstream of the module will be affected. In addition, tracing the location of the fault is much simpler because the section of the line in which the fault occurred is known from the protection circuit that has tripped.
Patent DE-69215897-D1 (DE)
Inventor: EMMONS DAVID
IPC: G02B6/38
Filed: 1992-08-28
Granted: 1997-01-23
Abstract: A variable attenuator for a fiber optic transmission system includes first and second optical fibers which are axially aligned. The fibers are provided with spherical polishes. The radius of each of the fibers originates at an axis which is offset from an axis of the fiber cores.
Patent DE-69312849-D1 (DE)
Inventor: NICOLA MASSIMO
IPC: A61K31/19
Filed: 1993-02-26
Granted: 1997-09-11
Abstract: New pharmacologically active derivatives of N-(2-mercapto-acetyl) homocysteine, both in its cyclised  gamma -thiolactonic form or in the open chain form are described, such derivatives having formula (I) wherein R represents a hydrogen atom, a C1-3 alkyl, a C7-9 aralkyl or a group COR1 in which R1 is a C1-3 alkyl or a C7-9 aralkyl, the aralkyl groups being unsubstituted or substituted on the phenyl ring by one or more halogens, C1-3 alkyl or C1-3 alkoxy; L is hydrogen, Q is hydroxy, or L and Q, together, form a bond. The process for the preparation of the above compounds as well as the pharmaceutical compositions containing them are also described. The above compounds are potent free-radical scavenging agents. They can prevent the cellular damage induced by free radicals and they have additional local antiinflammatory, mucolytic and mucokinetic activities. Therefore, the compounds may be useful in the treatment of acute and chronic bronchitis, emphysema, acute and chronic ORL pathologies, as antidotes against drug-induced depletion of endogenous glutathione and in case of alteration of the biological oxidant-antioxidant balance.
Patent DE-69326386-D1 (DE)
Inventor: WALSER ARMIN
IPC: C07D487/04
Filed: 1993-06-09
Granted: 1999-10-21
Abstract: The present invention is directed to imidazo[1,5-a] [1,4]benzodiazepine-3-carboxamide compounds of the formula: <CHEM> wherein R is hydrogen, CH3CH2-, CH2=CHCH2-, (CH3)2CH-, CH3CH2CH2-, or   <CHEM> or a pharmaceutically acceptable salt thereof. These compounds and their pharmaceutically acceptable salts possess anti-anxiety and anti-epileptic activity.
Patent DE-69332577-D1 (DE)
Inventor: SHIBANO MITSUGI
IPC: A61P33/00
Filed: 1993-09-01
Granted: 2003-01-30
Abstract: An intermediate useful in the synthesis of milbemycin derivatives having an ether bond at the 13-position and which is represented by the general formula (IIId) : <CHEM> wherein R represents a methyl group, an ethyl group, an isopropyl group or a sec-butyl group, and R<5> and R<6'> each individually represents a hydrogen atom or a protecting group, and related precursors as well as to a process for producing these intermediates.
Patent DE-69401260-D1 (DE)
Inventor: BETTRIDGE DAVID FREDERICK
IPC: C23C4/06
Filed: 1994-11-01
Granted: 1997-02-06
Abstract: A coating composition comprising an alloy having the formula RCrAlR'R'' wherein R is nickel, cobalt or the like; R' is yttrium or hafnium and R'' is tantalum, rhenium and/or platinum, preferably mixed with an oxide dispersion such as alumina, to provide an improved class of coatings suitable for operating in high temperature oxidizing environments.
Patent DE-69403138-D1 (DE)
Inventor: LEWINER JACQUES
IPC: G07B15/06
Filed: 1994-06-02
Granted: 1997-06-19
Abstract: This is a device intended to inform the users of a bus network about the waiting times for buses at the stops of the network, which devices comprise a central set capable of transmitting radio signals relating to the actual instantaneous positions of the buses and portable receiver units (1) capable of displaying the waiting times on screens (4). Each unit can itself serve as ticket or travel pass, it carrying for this purpose (at 10) a "validity" datum (corresponding to a sum of money or to an end-of-subscription date) which can be inspected remotely by ticket-validating machines (9) and which can itself be "reloaded" remotely from the central set. <IMAGE>
Patent DE-69404589-D1 (DE)
Inventor: WINBERG RAGNAR
IPC: G09F11/02
Filed: 1994-09-14
Granted: 1997-09-04
Abstract: The present invention relates to a method and a device for applying a removable message on a sign for consecutive repeated presentation of series of images and of the type wherein each image is made up of a plurality of image portions located on rotatable prisms or display screens having a cross section such as that of an equilateral triangle and wherein the same poster blades as for common billboards are used. The object of the invention is to permit an easier, safer and quicker replacement of messages. This is arrived at by providing each screen side (3) with a plastic foil (4) which covers said screen side and which is located at a small distance outside the screen side and by inserting from below into the space provided therebetween, the message in the form of a paper strip (28) by means of a rigid band (22) which from a coiled position on a tool located on a lower beam (1) of the sign is brought to enter between the screen-side and the plastic foil and to the uppermost portion (27) of which the incoming paper strip (28) is momentarily attached. <IMAGE>
Patent DE-69408827-D1 (DE)
Inventor: CLATWORTHY JOHN
IPC: E02D31/02
Filed: 1994-10-11
Granted: 1998-04-09
Abstract: Liquid-repellant covering layer, characterized in that it consists of at least a compact layer (2) which is formed by a mass of fibers (3) and a clay product (4). <IMAGE>
Patent DE-69431929-D1 (DE)
Inventor: LANIER Z
IPC: G06F3/038
Filed: 1994-09-29
Granted: 2003-01-30
Abstract: A database (56) stores image data corresponding to an image which extends along first and second generally perpendicular image axes. A display device (14) is mounted for movement with the user's head in proximity to the user's eye, and an image generating circuit (54) generates a portion of the image on the display device (14) using coordinate data which varies only for the first and second image axes. A movement measuring circuit (58) includes a plurality of radiation emitters disposed about the person's body part and a sensor (38) disposed at a fixed reference point which detects the identity of the radiation emitters and/or the intensity of radiation emitted by each emitter.
Patent DE-69434352-D1 (DE)
Inventor: FOX PETER DAVID
IPC: G08B17/107
Filed: 1994-08-01
Granted: 2005-05-25
Abstract: A smoke detection system includes a microprocessor 45 which performs a statistical analysis wherein newer readings for the smoke content of an air stream are accorded greater influence on outputs from the microprocessor than are older readings, which became gradually less influential. The arriving readings are sorted into classes, the class into which a newer reading is sorted being incremented by an amount dependent upon the existing entry in the class and the other classes being decremented by amounts dependent upon their existing entries. The statistical analysis is used to set an abnormal threshold for the readings and to ascertain when a centre of distribution of the readings passes the threshold and to activate a warning. An impurity content detector has an annular mirror which encircles a light beam along which the impure air is forced to flow, the mirror reflecting the light back to a light sensor beside the light source. An air-speed detector operates upon the basis of tending to keep the temperature of its electrically-heated sensor at a constant difference above the air temperature as measured by an adjacent reference detector, the air speed being dependent upon the increase in electrical power dissipated in the electrically heated sensor. <IMAGE>
Patent DE-69504773-D1 (DE)
Inventor: STREIT BERNARD
IPC: H02G9/06
Filed: 1995-05-03
Granted: 1998-10-22
Abstract: The protective sheath has at regular intervals (d) on its exterior surface a gap (14) whose width is greater than the gap width (10) between successive ribs (12) on the sheath wall. A fixing clip (20) associated with the sheath, has on its internal face (20), surrounding the sheath, a rib (26) which is designed to fit into the gap (14). <IMAGE>
Patent DE-69508350-D1 (DE)
Inventor: AALTO ESA
IPC: B65H19/29
Filed: 1995-06-09
Granted: 1999-04-22
Abstract: PCT No. PCT/FI95/00334 Sec. 371 Date May 28, 1996 Sec. 102(e) Date May 28, 1996 PCT Filed Jun. 9, 1995 PCT Pub. No. WO95/34495 PCT Pub. Date Dec. 21, 1995A method and a device for finishing the surface layers of the machine reel (13) that is formed during reeling of the web (P). In the method; a member (20) that presses the web is brought onto the face of the reel (12) that is being completed before the reel (12) that is being completed is transferred to the reel change position. The full reel (12) is transferred to the reel change position so that the member (20) that presses the web during nip-free reeling forms a contact with the web, which contact prevents access of air between the web layers, and follows the full reel (12) during its transfer to the reel change position. During the reeling of the surface layer to be finished, the member (20) that presses the web is shifted apart from the face of the reel (12) that is being completed along such a path (D) of movement that the member (20) that presses the web maintains a contact of the desired extent with the face of the reel (12) that is being completed.
Patent DE-69508943-D1 (DE)
Inventor: VAN DEN HAAK ABRAHAM
IPC: A61M5/315
Filed: 1995-07-10
Granted: 1999-05-12
Abstract: An injection assembly comprising a liquid container with an outflow opening and a piston displaceable therein, a suction needle with a needle fitting which is adapted to be releasably fitted in the outflow opening of the liquid container, and an injection needle with a needle fitting which is adapted to be permanently fixed on the outflow opening of the liquid container, said assembly further comprising an auxiliary coupling part which is fixed in the outflow opening of the liquid container, which is connected with the needle fitting of the injection needle and which comprises second coupling means which are permanently coupled with the first coupling means of the piston in the presence of the injection needle, which coupling cannot take place in the presence of the suction needle.
Patent DE-69517993-D1 (DE)
Inventor: NAZARE EDGARD
IPC: F02M69/08
Filed: 1995-10-18
Granted: 2000-08-17
Abstract: PCT No. PCT/FR95/01372 Sec. 371 Date Jun. 23, 1997 Sec. 102(e) Date Jun. 23, 1997 PCT Filed Oct. 18, 1995 PCT Pub. No. WO96/12886 PCT Pub. Date May 2, 1996A device for transforming internal combustion engines using liquid fuel into over-pressurized engines using gas. Liquid fuel is fed into an annular chamber surrounding a needle. The fuel and primary air is injected at a controlled flow and pressure into a choke chamber to form an air-fuel premixture made of very fine microdrops. During the downstroke of the piston, the premixture is aspirated, causing the projection of the premixture against the blades of a rotor which rotates at high speed. The gasification chamber is then over pressurized during the closing of the intake valve and the introduction of the mixture.
Patent DE-69518974-D1 (DE)
Inventor: NOAKES JAMES
IPC: A61M15/02
Filed: 1995-04-24
Granted: 2000-11-02
Abstract: An electrostatic spraying device for use in spraying inter alia personal care and personal hygiene products comprises an outlet (94) from which the product issues in the form of an electrostatically charged spray and a control member (60, 60a) for attenuating the potential gradient in the vicinity of the outlet (94) to such an extent that spraying is suppressed until the device is brought to within a predetermined distance from a site to be spayed.
Patent DE-69519796-D1 (DE)
Inventor: TABITI KARIM
IPC: G01N33/574
Filed: 1995-06-06
Granted: 2001-02-08
Abstract: PCT No. PCT/EP95/02166 Sec. 371 Date Mar. 10, 1997 Sec. 102(e) Date Mar. 10, 1997 PCT Filed Jun. 6, 1995 PCT Pub. No. WO95/34818 PCT Pub. Date Dec. 21, 1995A method for diagnosis or prognosis of a cancer is disclosed. The method comprises (i) detecting in a first biological sample protein tyrosine phosphate  alpha  (PTP alpha ) or PTP alpha  nucleic acid, and (ii) comparing the level of PTP alpha  or PTP alpha  nucleic acid in the first sample with the level in a second biological sample known to be from normal tissue. Any overexpression of PTP alpha  or PTP alpha  nucleic acid in the first sample compared to the second sample is indicative that the first sample is from a cancerous tissue.
Patent DE-69525790-D1 (DE)
Inventor: ABILEAH ADIEL
IPC: G02F1/1335
Filed: 1995-06-07
Granted: 2002-04-18
Abstract: A normally white liquid crystal display is provided with a positively birefringent uniaxial retardation film having a retardation value of from about 100 - 200 nm. The retardation film is provided on one side of the liquid crystal layer, the liquid crystal being sandwiched between a pair of orientation or buffing films which orient the liquid crystal molecules adjacent thereto in predetermined directions. The optical axis of the retardation film is rotated from about 2 DEG  - 20 DEG , most preferably from about 6 DEG  - 10 DEG relative to the buffing direction on the opposite side of the liquid crystal layer. This rotation of the retardation film optical axis allows for the high contrast ratio viewing zone of the display to be shifted vertically into either the positive or negative vertical viewing region depending upon the direction of rotation of the retardation film optical axis. Alternatively, biaxial retardation films having similar retardation values may be utilizied according to the teachings of this invention. <IMAGE>   <IMAGE>