baber/WOPTO huggingface dataset:
Patent AU-2021209148-A1 (AU)
Title: Methods of inactivating viral contaminants
Inventor: ABRANTES FILIPA
IPC: A61K39/395
Filed: 2021-07-26
Abstract: The present invention relates to a method for preparing an antibody-containing solution free 
of viral contaminants starting from cultured cells are described. The method include a step 
of subjecting the antibody containing solution to a mix of solvent and detergent or to high 
5 pH.  
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Patent AU-2021212310-A1 (AU)
Title: Methods for improved cancer treatment
Inventor: REGENBRECHT CHRISTIAN
IPC: C12Q1/6886
Filed: 2021-01-29
Abstract: The invention relates to a method for determination whether to start or to continue a treatment of cancer, especially the treatment by MEK inhibitors, which are widely used in oncology. The inventive method discloses a) measuring at least one characteristic of at least one biomarker in at least one biological sample comprising tumor cells of at least one tumor site of a tumor; b) determining a loss or mutation of at least one marker gene in the at least one biological sample by use of the at least one biomarker; c) determining to start or to continue treatment with the at least one inhibitor if the measurement indicates that the tumor cells in the at least one biological sample comprise the at least one marker gene whose mutational status indicates a favorable outcome, whereby the at least one inhibitor is selected specifically in view of the determination of the mutational status of the at least one marker gene; wherein the at least one marker gene is a tumor suppressor related to the activity of transforming growth factor- β / bone morphogenetic protein (TGF-β/BMP) pathway. Further, the present invention relates to a biomarker corresponding to at least one marker gene, especially SMAD4 gene, and a use of the biomarker in the inventive method.
Patent AU-2021221138-A1 (AU)
Title: HLA Class I-restricted T cell receptors against RAS with G12D mutation
Inventor: LEVIN NOAM
IPC: C07K14/82
Filed: 2021-02-12
Abstract: Disclosed is an isolated or purified T cell receptor (TCR), wherein the TCR has antigenic specificity for a mutated human RAS amino acid sequence with a substitution of glycine at position 12 with aspartic acid presented by a human leukocyte antigen (HLA) Class I molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
Patent AU-2021229632-A1 (AU)
Title: Partial dehydrogenation of organic liquids
Inventor: BLANC JÉRÔME
IPC: C01B3/22
Filed: 2021-03-01
Abstract: The present invention concerns a process for producing hydrogen by partial dehydrogenation of an organic liquid, said process comprising a step of supplying at least one organic liquid having a Degree of Hydrogenation DHplus, a step of partially dehydrogenating said liquid, a step of recovering firstly gaseous hydrogen and secondly said organic liquid having a Degree of Hydrogenation DHminus, and in which the ratio DHplus/DHminus is between 1 and 25, endpoints excluded. The invention also concerns a hydrogenation/dehydrogenation cycle comprising at least the process for producing hydrogen by partial dehydrogenation of an organic liquid of the invention and at least one reaction of hydrogenation of said organic liquid.
Patent AU-2021242171-A1 (AU)
Title: Interleaf packing and deployment system
Inventor: MISULIA JOSEPH M
IPC: G01V1/16
Filed: 2021-01-18
Abstract: A packing module includes a volumetrically efficient structure for separately retaining sensors and a cable of a sensor array. The packing module includes a tray that supports the sensors and a retaining leaf arrangement that extends outwardly from the tray to retain the cable on the tray. The retaining leaf arrangement includes a plurality of nested leaves that are spaced relative to each other. Packing the module includes placing the sensors separately and in succession on the tray and inserting a portion of the cable in the retaining leaf arrangement in between each placing of a sensor. The placement of a sensor and insertion of a portion of the cable occurs alternately until the entire sensor array is accommodated. Deployment of the sensor array may occur by alternately removing a sensor and a portion of the cable until the sensor array is displaced from the module.
Patent AU-2021267172-A1 (AU)
Title: Agents to prevent tissue damage from clostridium difficile infections by inhibition of the gut-damaging bacterial toxins TcdA and TcdB
Inventor: SCHRAMM VERN L
IPC: A61K31/65
Filed: 2021-05-06
Abstract: Methods for treating or preventing diseases and conditions associated with
Patent AU-2021278088-A1 (AU)
Title: Rheology modifier and aminosilane waterborne admixture
Inventor: HOSTETTER MARISA
IPC: C09D5/00
Filed: 2021-04-16
Abstract: The present invention is a composition comprising an aqueous admixture of a neutralized or partially neutralized aminosilane and an associative thickener, wherein the admixture has a pH of less than 10.2. The admixture is beneficial as an easy-to-use paint additive that provides stain removal, stain blocking, and corrosion resistance for coatings from low VOC paints.
Patent AU-2021289697-A1 (AU)
Title: Damage evaluation device and damage evaluation method
Inventor: NAGAI YUUKI
IPC: G01N29/06
Filed: 2021-03-05
Abstract: This damage evaluation device (1) comprises a phased array probe (11) that emits an ultrasonic signal from the surface of inspection metal (22) toward the inside of the inspection metal (22) and detects reflected signals reflected from a prescribed area (Q1) inside the inspection metal (22), and a computation processing unit (14). The computation processing unit (14) sets a plurality of planes (qn) parallel with one another in the inspection area (Q1), calculates pixel data by quantifying the reflected signals from segments set in each of the planes (qn), calculates the degree of deviation of the pixel data, and evaluates damage to the inspection metal (14) on the basis of the degree of deviation.
Patent AU-2021290318-A1 (AU)
Title: Authentication Methods and Systems
Inventor: PIKE JUSTIN
IPC: G07F7/10
Filed: 2021-12-23
Abstract: The invention provides a solution for secure authentication of an individual. The 
invention comprises methods and apparatus for secure input of a user's identifier 
5 e.g. PIN. An image of a keypad is superimposed over an operable keypad within a 
display zone of a screen associated with an electronic device. The keypad image 
and/or the operable keypad are generated by the device using a scrambled or 
randomised keypad configuration generated on or at the electronic device. The 
configuration or order of keys depicted in the image may or may not be scrambled 
10 or randomised. Thus, the order of keys depicted in the image do not correspond to 
the order of the keys in the operable keypad, so that when the user selects a 'key' 
depicted in the image on the screen, the underlying operable keypad is caused to 
operate and an encoded version of the user's input is received into memory on the 
device. The encoded input can be sent for decoding on a remote computer. The 
15 keypad configurations used for generation of the operable keypad(s) and/or keypad 
image(s) are generated using an input. The input could be a true or pseudo random 
number or biometric data relating to a user of the device. The device may be a 
mobile phone, a tablet computer, laptop, PC, payment terminal or any other 
electronic computing device with a screen.  
20
Patent AU-2021314233-A1 (AU)
Title: System and method for bag closure clip production
Inventor: GREEN MARK
IPC: B65D33/16
Filed: 2021-07-22
Abstract: A system is configured to produce a series of printed clips (14p). The system includes a source (42) of web material (40), a cutting station (46), a drive assembly (70, 72) and a printing station (48). The web material (40) is configured to pass through the system in a machine direction (44). The cutting station (46) is configured to cut a first portion of the web material (40) into at least a first clip (12), index the first portion after cutting, and sequentially cut a second portion of the web material (40) into at least a second clip (12). Cut portions of the web material (40) exit the cutting station (46) in a free loop (14u). A drive assembly (70, 72) is configured to feed web material of the free loop (14u) through the printing station (48) at a web speed. The printing station (48) is configured to print indicia (16) on a first surface (18f, 18b) of the cut portions of the web material (40).
Patent AU-2021332331-A1 (AU)
Title: Recombinant adeno-associated virus for treatment of GRN-associated adult-onset neurodegeneration
Inventor: WILSON JAMES M
IPC: C07K14/475
Filed: 2021-08-26
Abstract: A therapeutic regimen useful for treatment of adult-onset neurodegenerative disease in a human patient comprising administration of a recombinant adeno-associated virus (AAV) vector having an AAV1 capsid and a vector genome comprising a progranulin (GRN) coding sequence is provided. Also provided are compositions comprising a recombinant AAV vector and methods of treating adult-onset neurodegenerative disease in a patient comprising administration of the recombinant AAV vector.
Patent AU-2021377754-A1 (AU)
Title: Combustor systems and methods
Inventor: MEDINA AGUSTIN VALERA
IPC: F23R3/34
Filed: 2021-11-03
Abstract: System comprising a gas turbine engine fuel injection apparatus (11) arranged to deliver to a combustion chamber (9) of a gas turbine engine a first injection fluid comprising a first fuel and a second injection fluid comprising a second fuel. The apparatus is arranged to deliver the first and second injection fluids in a manner such that the first injection fluid is delivered in a first stream and the second injection fluid is delivered in a second stream. Further, such that there is a delivery zone (47) corresponding to a first location at which both the first and second streams have been delivered in which the first stream is substantially radially surrounded by the second stream.
Patent AU-2021378635-A1 (AU)
Title: Headstand bench
Inventor: JOHNSTON MARNI NICOLE
IPC: A63B21/00
Filed: 2021-10-29
Abstract: A headstand bench has a bench frame having front and rear pairs of legs connected by a pair of upper rails, and a pair of lower rails extending longitudinally between the front and rear pairs of legs, beneath the pair of upper rails. A headstand plate is mounted on the pair of upper rails adjacent the rear pair of legs, the headstand plate having a first inner edge that includes an inwardly extending recessed area that is sized and shaped for performing headstand exercises. A removable rigid plate is adapted to be removably mounted on the pair of upper rails, and includes a second inner edge that removably interlocks with the first inner edge of the headstand plate. A removable cushion is removably mounted on the removable rigid plate. The removable rigid plate may also be secured on the pair of lower rails.
Patent AU-2021390519-A1 (AU)
Title: Sanitary fill head
Inventor: MILLA JOSE DANIEL
IPC: B65B3/04
Filed: 2021-12-02
Abstract: A filler head apparatus (20) for hygienically filling and emptying containers (22) through a fitment (24) incorporated with the container (22) includes a cylindrical outer housing (30) for receiving a hollow bore inner cylinder (32) which is actuated to simultaneously reciprocate and rotate about a central axis (33) within the outer housing. A transfer tube assembly (34) is mounted to the inner cylinder (32) to travel with the inner cylinder between an extended position engaged with the fitment (24) and a retracted position disengage from the fitment. When the transfer tube assembly is engaged with the fitment, flowable content or product may be transferred to or from the container (22). A fitment cap assembly (36) is also mounted to the inner cylinder (22) to travel with the inner cylinder to remove the cap (38) of the fitment (24) prior to either filling or emptying the container (22), and then to retract to a standby position while the container is filled/emptied, and thereafter replacing the fitment cap after filling/ emptying has been completed.
Patent AU-2021414396-A1 (AU)
Title: Surgical instrument to implant primary and secondary elements
Inventor: RUSSO ALESSANDRO
IPC: A61F2/30
Filed: 2021-12-23
Abstract: Template assembly including a surgical template (52, 152) comprising an elongated main body (54, 154) comprising at least one fixing member (70, 170) configured to cooperate with at least one corresponding fixing seat (32) of at least one rod- shaped and substantially rectilinear rigid primary element (12, 112, 212), wherein said main body (54) comprises first and second secondary through holes (72a, 72b, 72c; 72d, 72e, 72f) configured to respectively house thread-like and substantially rectilinear first secondary elements (34a, 34b, 34c; 134a, 134b, 134c; 234a, 234b, 234c) and second secondary elements (34d, 34e, 34f; 134d, 134e, 134f; 234d, 234e), wherein the first secondary holes (72a, 72b, 72c) define respective first secondary extension directions (Ya, Yb, Yc) for the first secondary elements (34a, 34b, 34c; 134a, 134b, 134c; 234a, 234b, 234c), and the second secondary holes (72d, 72e, 72f) define respective second secondary extension directions (Yd, Ye, Yf) for the second secondary elements (34d, 34e, 34f; 134d, 134e, 134f; 234d, 234e), the first and the second secondary extension directions (Ya, Yb, Yc; Yd, Ye, Yf) being oblique to one another.
Patent WO-2023279141-A1 (WO)
Title: Production d'hydrogène à partir d'air
Inventor: LI GANG
IPC: C25B1/04
Filed: 2022-06-30
Abstract: La présente invention concerne un procédé de production d'hydrogène à partir d'air qui consiste à : mettre en contact un liquide hygroscopique avec une source d'air pour absorber une teneur en eau à partir de ladite source d'air dans le liquide hygroscopique ; et convertir électrolytiquement l'eau absorbée dans le liquide hygroscopique en hydrogène et en oxygène.
Patent AU-2022202215-A1 (AU)
Title: A steel, a welding consumable, a cast, forged or wrought product, a method of welding, a welded product and a method of heat treating
Inventor: GOODWIN RICHARD STANLEY
IPC: C21D1/18
Filed: 2022-04-01
Abstract: A Steel, a Welding Consumable, a Cast, Forged or Wrought Product, a Method of 
Welding, a Welded Product and a Method of Heat Treating 
5 
A welding consumable including, in mass %: 0.015% or less carbon; 0.05 to 0.35% silicon, 
7.45 to 10.5% nickel; 2.00% or less manganese; 0.025% or less sulphur; 0.030% or less 
phosphorous; 24.0 to 27.0% chromium; 0.00 to 1.00% copper; 3.0 to 4.5% molybdenum; 
0.75% or less cobalt; 0.010% or less niobium; 0.015% or less aluminium; 0.20 to 0.300% 
10 nitrogen; 0.00 to 1.00% tungsten; the balance being iron and incidental impurities.  
Fig. 4
4/8 
Fig. 4 
C% Si% Mn% P% S% Cr% 
0.01 0.29 0.69 0.024 0.0003 25.29 
Mo% Ni% Cu% N% W% Al% 
3.58 9.24 0.57 0.22 0.63 0.013 
Ti % Sn% Nb% Co% B% V % 
0.005 0.004 0.006 0.04 0.0023 0.08
Patent AU-2022220924-A1 (AU)
Title: Tricyclic derivatives useful as parp7 inhibitors
Inventor: LI HAIJUN
IPC: C07D471/06
Filed: 2022-01-26
Abstract: Provided are a compound of formula (I) that inhibit the activity of PARP7, a stereoisomer thereof, a deuterated derivative thereof, or a pharmaceutically acceptable salt thereof, an intermediate to prepare the compound, a process to prepare the compound, a composition comprising the same, and the methods of using the same.
Patent AU-2022232216-A1 (AU)
Title: Protease cleavable prodrugs
Inventor: BOSSHART ANDREAS
IPC: C07K16/28
Filed: 2022-03-09
Abstract: The application relates to prodrugs comprising a drug molecule connected by a protease-cleavable peptide linker to a binder, which reversibly inhibits a biological activity of the drug molecule, and to the inhibitory binders themselves. Also described are nucleic acids encoding the recombinant proteins described herein, and methods of making said recombinant proteins, as well as methods of treatment and medical uses of the recombinant proteins.
Patent AU-2022234206-A1 (AU)
Title: Adaptable asymmetric medicament cost component in a control system for medicament delivery
Inventor: LEE JOON BOK
IPC: G16H20/17
Filed: 2022-03-07
Abstract: The exemplary embodiments provide medicament delivery devices that use cost functions in their control systems to determine medicament dosages. The cost function may have a medicament cost component and a performance cost component. The exemplary embodiments may use cost functions having medicament cost components that scale asymmetrically for different ranges of inputs (i.e., different candidate medicament dosages). The variance in scaling for different input ranges provides added flexibility to tailor the medicament cost component to the user and thus provide better management of medicament delivery to the user and better conformance to a performance target. The exemplary embodiments may use a cost function that has a medicament cost component (such as an insulin cost component) of zero for candidate dosages for a range of candidate dosages (e.g., below a reference dosage).
Patent AU-2022238533-A1 (AU)
Title: Infusion device assembly
Inventor: KESSEL LAURA
IPC: A61M5/142
Filed: 2022-03-15
Abstract: A cassette for a drug delivery device may comprise a cassette base portion including a reservoir recess surrounded by an attachment surface. The attachment surface may include a reservoir outlet flow path recessed therein. The cassette may further comprise a reservoir film coupled to the attachment surface which, together with the reservoir recess, defines a flexible reservoir. A portion of the reservoir film may have a preformed shape which mimics the contour of the reservoir recess. The preform shape may cause the reservoir film to be disposed adjacent the surface of reservoir recess when the reservoir is in an empty state. The cassette may further comprise at least one duct recessed into the surface of the reservoir recess. Each of the at least one duct may define a flow path which remains in fluid communication with the reservoir outlet flow path when the reservoir is in an empty state.
Patent AU-2022241618-A1 (AU)
Title: Device, body, method and system for health-care
Inventor: TSAI CHING-FU
IPC: A61H39/04
Filed: 2022-09-30
Abstract: Device, Body, Method and System For Health-Care 
ABSTRACT OF THE DISCLOSURE 
A health care device includes a health care body for positioning a body part 
of a user, so as to maintain a first specific positional relationship with the body 
part, wherein the body part has an acupoint; an acupoint work piece for 
performing a health care work onto the use through the acupoint; and a work piece 
holder having a first end connected to the health care body and a second end for 
fixing the acupoint work piece, so that under the first specific positional 
relationship, the acupoint work piece performs the health care work under the 
condition that the acupoint work piece has a second specific positional 
relationship with the acupoint. A health care body, method and system are also 
provided.  
124
Patent AU-2022255691-A1 (AU)
Title: Rotisserie clamp
Inventor: CLEVELAND DAVID R
IPC: A47J37/04
Filed: 2022-04-04
Abstract: Rotisserie forks and a basket for use on a motorized elongated spit rod having a central axis and a sharpened tip, wherein the forks or basket have a) a split shaft collar having an opening that slidably receives the spit rod and has an inside diameter, and b) a lever-action quick-release clamp that surrounds the shaft collar, has open and closed lever positions, and which when open enables the shaft collar and fork or basket to move along the spit rod central axis, and which when closed reduces the shaft collar inside diameter so that the fork or basket does not move along the spit rod central axis during rotisserie grilling.
Patent AU-2022265693-A1 (AU)
Title: Phthalimido cereblon complex binders and transcription factor degraders and methods of use
Inventor: ZHANG TINGHU
IPC: A61K31/403
Filed: 2022-04-28
Abstract: Disclosed are compounds and pharmaceutically acceptable salts and stereoisomers thereof that may bind to CRBN complex and cause degradation of various proteins e.g., IKZF2 (Helios). Also disclosed are pharmaceutical compositions containing same, and methods of making and using the compounds to treat diseases and disorders characterized or mediated by the presence of a protein, and hence would benefit from degradation of said protein.
Patent AU-2022291205-A1 (AU)
Title: Additive manufacturing apparatus and method
Inventor: ZHU GUANG
IPC: B29C64/286
Filed: 2022-06-09
Abstract: An additive manufacturing apparatus (1) and method. The additive manufacturing apparatus (1) comprises: a light source (10), which provides lighting to cure a photocurable resin (40); a molding device (20), comprising a storage container (21), the storage container (21) being used for storing the photocurable resin (40), the molding device (20) having a molding surface (22), and the photocurable resin (40) being cured on the molding surface (22); and a light scattering mechanism (30), provided between the light source (10) and the molding surface (22), the light scattering mechanism (30) being capable of causing light of the light source (10) to diverge in the direction of propagation, so that the light intensity in pixels on the molding surface (22) changes. Protrusions and recesses of the surface of a printed three-dimensional object (50) are reduced, and the transparency of the printed three-dimensional object (50) is improved.
Patent AU-2022313541-A1 (AU)
Title: Aerosol provision system
Inventor: Xiao Zhihuang
IPC: A24F40/44
Filed: 2022-07-06
Abstract: An aerosol provision system 1 comprising an aerosolisable material transport element 34 for receiving aerosolisable material. The aerosolisable material transport element 34 comprises an aperture 60 extending through a thickness of the aerosolisable material transport element 34. The aerosol provision system 1 also comprises a conductive member 46, in the form of a conductive plate or a conductive foil, which is in contact with the aerosolisable material transport element 34, and comprising a thermally conductive surface 32B for receiving heat for transferring to the aerosolisable material transport element 34. The aerosolisable material transport element 34 is in contact with the conductive member 46 at a contact surface 48 from the conductive member 46, and the contact surface 48 is opposite the thermally conductive surface 32B. This arrangement allows for an efficient transfer of heat across the conductive member 46 to the aerosolisable material transport element 34.
Patent AU-2023203236-A1 (AU)
Title: Systems and methods for quantifying calorie values for a plurality of different caloric food categories
Inventor: WILSON JOSHUA P
IPC: A23L35/00
Filed: 2023-05-23
Abstract: A system for quantifying calorie values for a plurality of different caloric food 
categories includes a plurality of scoops. Each scoop of the plurality of scoops includes a scoop 
body having a respective internal volume and a first visual indicator. The system also includes a 
reference guide having a second visual indicator configured such that an association of the first 
visual indicator with the second visual indicator matches a first caloric food category of the 
plurality of different food caloric categories with a first one of the plurality of scoops, where at 
least one of the first visual indicator and the second visual indicator represents an amount of 
calories of the first caloric food category contained in the respective internal volume when 
substantially filled with the first caloric food category.