baber/WOPTO huggingface dataset:
Patent IL-125007-A0 (IL)
Title: Process for preparation of hydrazides
IPC: C07C243/28
Filed: 1996-12-19
Abstract: A process for producing a hydrazide of formula (1.0) is disclosed. The process comprises reacting a hydrazone of formula (2.0) or (2.1), wherein said hydrazone is in toluene, with a mixture of Grignard reagents, wherein said Grignard reagents are in a suitable organic solvent; wherein: (A) Z is a suitable carbonyl protecting group; (B) R is a suitable -OH protecting group; (C) R<1> is selected from: H, a non-enolizable alkyl, a non-enolizable substituted alkyl, aryl, substituted aryl, -S-aryl, -S-(substituted aryl), -S-alkyl, -S-(substituted alkyl), alkoxy, substituted alkoxy, aryloxy, or substituted aryloxy; (D) said mixture of Grignard reagents comprises R<2>MgX in admixture with R<3>MgX; (E) R<2> is a suitable alkyl, substituted alkyl, alkenyl, alkynyl, aryl, substituted aryl, or aralkyl group capable of adding to the -C=N group of the hydrazone to produce the hydrazide; (F) R<3> is a suitable alkyl, substituted alkyl, aryl or substituted aryl group that is more sterically hindered than said R<2> group; (G) X is independently selected from Cl, Br or I for each Grignard reagent; (H) when said hydrazone is a compound of formula (2.0) then the reaction is conducted at a temperature of about +30 to about -40  DEG C; and (I) when said hydrazone is a compound of formula (2.1) then the reaction is conducted at a temperature of about +40 to about -20  DEG C.
Patent IL-131225-A0 (IL)
Title: A carbide-containing component coated with a hard material and processes and devices for the production thereof
IPC: C23C16/02
Filed: 1998-02-05
Abstract: A process for the production of a component coated with a hard material such as a tool. The process involves: (i) introducing a fine-grained cemented carbide or carbide-containing cermet substrate into a vacuum system; (ii) removing carbon from the carbides of a surface layer of the substrate; (iii) introducing carbon into the surface layer; and (iv) coating the substrate with the hard material. The temperature of the substrate in steps (ii) and (iii) is 900-1400[deg] C. Step (ii) is conducted in an oxygen-containing atmosphere and step (iii) is conducted in a carbon-containing atmosphere. The vacuum system contains a heating device and at least one gas feed connection. Also claimed is a component having an inner cemented carbide cermet substrate and an outer hard material layer, preferably of diamond. The grain size of the substrate is less than one micron and the surface layer has a grain size of less than 10 mu m.
Patent IL-135051-A0 (IL)
Title: Apo-3 ligand polypeptide
IPC: A61K38/00
Filed: 1998-10-09
Abstract: A tumor necrosis factor and lymphotoxin homolog having apoptotic activity, identified as Apo-3 Ligand, is provided. Nucleic acid molecules encoding Apo-3 ligand, chimeric molecules and antibodies to Apo-3 Ligand are also provided.
Patent IL-139981-A0 (IL)
Title: Combined laser/flir optics system
IPC: G05B23/02
Filed: 2000-11-29
Abstract: In a FLIR/laser based targeting and imaging system, the ability to recognize, detect, locate, and/or track targets in an area of interest is significantly improved by reducing the fixed and dynamic alignment errors between the IR LOS and the laser LOS. Fixed alignment errors are reduced with an improved internal boresight module and corresponding boresight method. Dynamic alignment errors are reduced with an opto-electric subsystem that employs a single pitch bearing and a common pitch/yaw afocal for both the laser energy and the IR energy. A segmented window in the system housing includes a circular EMI grid pattern which significantly reduces the amount of off-axis EMI entering the optical pathways, and improved signal processing techniques are employed to enhance the quality of the IR image after the image has been digitized.
Patent IL-147027-A0 (IL)
Title: Process for the preparation of 5-and/or 6-substituted-2-hydroxybenzoic acid esters
IPC: C07C51/09
Filed: 2000-07-10
Abstract: There is provided a single-step process for the preparation of a compound of formula I.Compounds of formula I are useful as starting materials in the synthesis of natural products and in the manufacture of benzophenone fungicidal agents.
Patent IL-150569-A0 (IL)
Title: Wound dressing and process for the manufacture thereof
IPC: A61F13/00
Filed: 2001-01-03
Abstract: A wound dressing is provided that serves a unique dual-purpose role. One surface of the dressing is comprised of a polyurethane foam and the other surface is comprised of a non-adherent thin-film of polydimethylsiloxane and polytetrafluoroethylene interpenetrating polymer networks ("IPN"). With the foam side of the dressing down against the wound, the product provides an adhesive surface for difficult fixation conditions. With the IPN side of the dressing against the wound, the dressing provides a non-adherent covering for fragile and sensitive wounds.
Patent IL-150881-A0 (IL)
Title: Process for preparing quinolylacrylonitrile and intermediates therefor
IPC: C07D215/12
Filed: 2001-01-24
Abstract: 3-Ä2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolylÜprop-2-enenitrite is prepared by reacting 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde with acetonitrile in the presence of a base and then adding a dehydrating to the reaction mixture to conduct dehydration. Under ordinary conditions, novel 3-Ä2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-ylÜ-3-hydroxypropionitrile is formed as an intermediate in the above reaction. Incidentally, when the above reaction is conducted in an organic solvent, 3-Ä2-cyclopropyl-4-(4-fluorophenyl)-3-quinolylÜ-prop-2-enenitrite is directly formed.
Patent IL-158983-A0 (IL)
Title: Plate and method for high throughput screening
IPC: C12N5/04
Filed: 2002-05-29
Abstract: A multiple well plate and method for media exchange, including a body defining a plurality of cell wells each connected via a channel to one of a plurality of aspiration holes, is provided. The cell wells contain a porous, hydrophilic frit which is suspended on a ledge above a reservoir of fluid media and supports a tissue sample. The properties of the frit wick the fluid media upwards to supply the tissue sample with nutrients for growth and proliferation. Old media is aspirated from the wells by a liquid handling device which inserts a pipette tip into the aspiration holes. The pipette tip applies a suction pressure which draws the media out of the cell well, through the channel, into the aspiration hole and out through the pipette tip. New media is dispersed through the pipette tip and directly into the cell well.
Patent IL-186015-A0 (IL)
Title: A broadband anthenna
Filed: 2007-09-18
Abstract: The antenna (1) has an outer element (3) comprising a rolled-up electrically conductive sheet disposed around a central longitudinal radiating element (2) without electrical contact. The outer element presents a height that is strictly decreasing or alternatively that increases and decreases along the roll.
Patent IL-201395-A0 (IL)
Title: Method for manufacturing a recombinant polyclonal protein
Filed: 2009-10-11
Abstract: The invention relates to a method for manufacturing a recombinant polyclonal protein composition, in particular a recombinant polyclonal antibody composition. The method comprises obtaining a collection of cells transfected with a collection of variant nucleic acid sequences, wherein each cell in the collection is transfected with and capable of expressing one member of the collection, which encodes a distinct member of a polyclonal protein. The cells are cultured under suitable conditions for expression of the polyclonal protein, which is obtained from the cells or culture supernatant. The nucleic acid sequence is introduced into the cells by transfection with a collection of vectors. The present method is suitable for manufacturing recombinant polyclonal antibodies for therapeutic uses.
Patent IL-202270-A0 (IL)
Title: Therapeutic pyrazoloquinoline derivatives
Filed: 2009-11-22
Abstract: The invention provides a novel chemical series of formula I, as well as methods of use thereof for binding to the benzodiazepine site of the GABAA receptor and modulating GABAA, and use of the compound of formula I for the treatment of GABAA receptor associated disorders. The general structure of formula I is shown below and can exist in tautomeric forms: The invention further provides a method of modulation of one or more GABAA subtypes in an animal comprising administering to the animal an effective amount of a compound of formula (I).
Patent IL-204662-A0 (IL)
Title: Composition
Filed: 2010-03-22
Abstract: The present invention relates to a composition which comprises the following myelin basic protein peptides: MBP 30-44; MBP 83-99; MBP 131-145; and MBP 140-154. The composition may be used to treat a disease, in particular multiple sclerosis and/or optical neuritis and the invention also relates to such uses and methods.
Patent RO-130465-A0 (RO)
Title: Instrument for personal hygiene
Inventor: CRISTEA OCTAVIAN
IPC: A46B15/00
Filed: 2015-04-01
Abstract: The invention relates to an instrument for personal hygiene which is used for cleaning the foot sole and the spaces between toes. According to the invention, the instrument consists of a flat rod () made of plastic, wood or metal, which, at one end, has a grip () followed by a straight portion () and a curved portion () which ends with a T-shaped semi-round profile (), on the curved portion () and the semi-round profile () there being applied, by gluing or any other method, a synthetic material (), soft enough to prevent the skin irritation, which has the role of removing, by scraping, the dead skin from the space between toes and from the foot sole.
Patent AP-2002002651-A0 (AP)
Title: Sodium-hydrogen exchanger type 1 inhibitor (nhe-1)
Inventor: CHEN WEICHAO GEORGE
IPC: C07D/
Filed: 2001-02-28
Abstract: NHE-1 inhibitor, method of using the NHE-1 inhibitor and pharmaceutical compositions containing the NHE-1 inhibitor. The NHE-1 inhibitor is useful for the reduction of tissue damage resulting from tissue ischemia
Patent AU-2002951740-A0 (AU)
Title: Feedthrough for electrical connectors
IPC: A61N1/05
Filed: 2002-09-30
Abstract: A method (10) of forming an electrically conducting feedthrough. The method (10) comprises a first step (11) of forming an electrically conductive structure (21) comprising a sacrificial component and a non-sacrificial component. At least a portion of the non-sacrificial component can then be coated with a relatively electrically insulating material (35) prior to removal of at least a portion of the sacrificial component from the electrically conductive structure. The structure of the feedthrough provides electrical connection through the wall of a housing of an implantable component while preventing unwanted transfer of materials between the interior of the component and the surrounding environment.
Patent IE-910044-A1 (IE)
Title: Vacuum cleaner
IPC: A47L5/32
Filed: 1991-01-07
Abstract: A convertible vacuum cleaner includes a nozzle base (10) and a motor and filter housing (60) rotatably mounted on the nozzle base. The nozzle base (10) is movable along a floor surface and includes a brush chamber (12) for mounting a rotatable brush (14) and a first suction passage (24) communicating with the brush chamber (12) at one end and with an exterior periphery of the nozzle base (10) at the other end. The motor and filter housing (60) includes a second suction passage (88) communicating at a first end with the first suction passage second end (28) and at a second end with an exterior periphery of the motor and filter housing. The motor chamber (66) is formed in the motor and filter housing (60) in spaced relation to the second suction passage (88). A suction chamber (122) is disposed in the motor and filter housing (60) in a spaced manner from the second suction passage (88) and the motor chamber (66). The suction chamber (122) has an inlet port (130) communicating with the exterior periphery (96) of the motor and filter housing (60). A flexible hose (140) is mounted outside the motor and filter housing (60), the hose (140) having a first end (146) communicating with the second suction passage second end (94) and a second end (142) communicating with the suction chamber inlet port (130). The flexible hose first end (146) can be selectively removed from communication with the second suction passage (88) to enable the vacuum cleaner to be used with associated cleaning tools.
Patent MC-2306-A1 (MC)
Inventor: VAHLE ANDERS
IPC: A61K38/00
Filed: 1991-08-20
Abstract: It has now been found that relatively short peptides such as the tripeptide glycyl-prolyl-glycine are able to effectively inhibit HIV infection of cells and syncytia formation between HIV infected and and non-infected cells. The peptides are suitable for therapy of patients infected with HIV and in prevention of HIV infection.
Patent MA-40806-A1 (MA)
Title: Échangeur de chaleur à faisceau tubulaire muni d'éléments de faisceau tubulaire agencés séquentiellement
Inventor: FANI YAZDI SAYYED AHMAD
IPC: F28D7/16
Filed: 2016-02-15
Abstract: L'invention vise à augmenter la surface d'un échangeur de chaleur sans qu'il ne soit nécessaire d'agrandir le diamètre total d'un échangeur de chaleur à faisceau tubulaire. à cet effet, l'invention concerne un échangeur de chaleur à faisceau tubulaire (1) dans lequel un faisceau tubulaire (2) composé de plusieurs tubes (20, 22, 27) présentant au moins un fond de tube (25, 26) est agencé dans un espace enveloppant (3). L'échangeur de chaleur à faisceau tubulaire (1) est délimité vers l'extérieur par une su
Patent MA-45513-A1 (MA)
Title: Bouchon pour conditionnements
Inventor: BERROA GARCÍA FRANCISCO JAVIER
IPC: B65D55/00
Filed: 2019-04-09
Abstract: Il permet à l'utilisateur deux modes possibles de distribution de liquide, en fonction du versement 5 plus ou moins important voulu, en permettant également la régulation et le contrôle de leur écoulement, tout cela de manière simple et aisée, avec une ouverture maximale de chacun des couvercles, le bouchon (1) pour conditionnements comprenant une base (10) pour sa fixation à l'embouchure d'un conditionnement, deux embouts (20a, 20b) logés à l'intérieur de la base (10) et émergeant par le haut, où chaque embout (20a, 20b) a une ouverture (21a, 21b) pour la distribution 10 du contenu du conditionnement (1); et deux couvercles (30a, 30b) indépendants entre eux, logés sur la base (10) en correspondance avec chacun des embouts (20a, 20b), de manière que lesdits couvercles (30a, 30b) sont rabattables entre une position d'ouverture et une position de fermeture.
Patent MA-51953-A1 (MA)
Title: Film de peinture aux propriétés antibactériennes et antivirales
Inventor: PAULOS CHARLES ALBERT
IPC: C09D5/14
Filed: 2020-12-22
Abstract: Depuis de nombreux siècles, l’argent est connu pour ses propriétés antibactériennes. Il était de tradition, dans les milieux aisés, d’offrir comme cadeau de naissance des couverts en argent ou une timbale. Jusqu’au début de xxe siècle, son utilisation s’est répondue, dans divers domaines, pour purifier l’eau, guérir les plaies, utilisation d’instruments de chirurgie. Avec la découverte des antibiotiques, l’utilisation de l’argent s’est considérablement réduite. Cependant, avec la résistance des bactéries aux antibiotiques observées ces dernières décennies et, la prolifération des infections nosocomiales, l’intérêt pour l’utilisation de l’argent renaît de ses cendres. De plus en plus de publications tendent à prouver le caractère antibactérien de l’argent. Nous savons maintenant que ce sont les ions ag+ qui apportent une telle action antibactérienne. En effet, les ions ag+, ont un mode d’action multidirectionnel contre les bactéries. Ils interfèrent avec la membrane cellulaire des bactéries en modifiant le transport d’électrons et en se liant à l’adn (15). De plus, des études en toxicologie, ont démontré que les ions ag+ agissent à de faibles concentrations contre les bactéries mais, qu’il est nécessaire d’avoir des grandes concentrations pour s’attaquer aux cellules (16). Les études des ions ag+ sur les virus sont moins courantes mais, ont démontrées une action inhibitrice sur des cellules contaminées par le virus du sida (17). Nous avons prouvé, que coloclean, en combinant, un polymère pure acrylique, avec une 15%
Patent UY-26863-A1 (UY)
Title: Derivados de la piperazina
Inventor: RICHTER HANS
IPC: A61P25/28
Filed: 2001-07-30
Abstract: La presente invención se refiere a compuestos químicos de la fórmula I, así como a sales, solvatos y ésteres farmacéuticamente aceptables de los mismos, en los que de R1 a R8 tienen los significados definidos en la reivindicación. Pueden utilizarse en forma de preparaciones farmacéuticas para el tratamiento de trastornos del sistema nervioso central, lesiones del sistema nervioso central, trastornos cardiovasculares, trastornos gastrointestinales, diabetes insípida, obesidad y apnea nocturna
Patent UY-27588-A1 (UY)
Title: Lactamas como antagonistas de taquiquininas
Inventor: STOBIE ALAN
IPC: A61P37/08
Filed: 2002-12-17
Abstract: Lactemas como antagonistas de taquiquininas . Esta invención se refiere a compuestos de fórmulas I: o una sal profármaco, solvato o polimorfo farmacéuticamente aceptable del mismo, agente terapéutico de la familia de la lactama y procesos para su preparación, intermedio utilizados en su preparación, composiciones que los contienen y usos de dichos derivados, útiles para prevenir o tratar enfermedades: inflamatorias, enfermedades causadas por helicobacter pylori u otras bacterias gran negativas positivas de ureasa, afecciones urológicas, alergia, vaso espástica, fibrosante o del colágeno, distrofia simpática refleja, neuropatia periférica, reumática oftálmica, dolor agudo o crónico o enfermedad viral, y trastornos: del sistema nervioso central (SNC), gastrointestinal (gi) , pulmonar, de relacionado con estres, neuropatológico, trastorno relacionado con potenciación o supresión inmunes.
Patent UY-30683-A1 (UY)
Title: Acido l-glutamico marcado con [f-18], l-glutamina marcada con [f-18], sus derivados y su uso, asi como procedimientos para su preparacion.
Inventor: MATHIAS BERNDT
IPC: A61K51/04
Filed: 2007-10-31
Abstract: Se describen los compuestos y la síntesis de ácido L-glutámico marcado con [F-18], L-glutamato marcado con [f-18], sus derivados de acuerdo con la formula (I) y sus usos
Patent AT-518195-A1 (AT)
Title: Verfahren zur Verdichtung der Schotterbettung eines Gleises sowie Stopfaggregat
IPC: E01B27/17
Filed: 2016-01-26
Abstract: Unterhalb von Schwellen eines Gleises befindlicher Schotter (3) wird durch Eintauchen und Beistellen von in Schwingungen versetzten Verdichtwerk- zeugen (7) verdichtet. Die während des Verdichtvorganges in den Schotter (3) eingeleiteten Schwingungen werden als Maß für die Schotterverdichtung registriert. Damit ist auch bei unterschiedlichen Schottereigenschaften ein homogen verdichte- tes Gleis erzielbar.
Patent ES-155992-A1 (ES)
Title: Procedimiento para el servicio de un arco voltaico
IPC: H05B31/00
Filed: 1942-02-11
Abstract: Procedimiento para el servicio de un arco voltáico caracterizado porque a la corriente contínua que alimenta el arco se superpone una corriente alterna.
Patent ES-178622-A1 (ES)
Title: Un método, con el aparato correspondiente, para hacer funcionar modelos accionados eléctricamente
Filed: 1947-06-24
Abstract: Un método de hacer funcionar modelos accionados eléctricamente, del tipo especificado, en el cual el movimiento del modelo se obtiene comunicando al bogie motor o a las ruedas motrices de dicho modelo una serie de impulsos de accionamiento en la dirección de movimiento, comunicándose dichos impulsos a intervalos determinados de antemano y obteniéndose como resultado de la atracción entre un polo o polos magnéticos y un material magnético.
Patent ES-182068-A1 (ES)
Title: MEJORAS EN DISPOSITIVOS DE DESCARGA ELECTRoNICA
IPC: H01J25/587
Filed: 1948-02-05
Abstract: Mejoras en dispositivos de descarga electrónica, caracterizadas por un magnetrón que comprende un cátodo alargado, una variedad de aletas mecánicas igualmente espaciadas, extendiéndose radialmente hacia fuera del referido cátodo, estando espaciados los extremos interiores de las referidas aletas uno del otro y el referido cátodo, estando el espacio entre cada para de aletas en comunicación abierta alrededor de los extremos salientes de las aletas con los espacios de los pares de aletas adyacentes y un imán de polos en los extremos del cátodo.
Patent ES-186252-A1 (ES)
Title: Un sistema perfeccionado de frenos para aviones
IPC: B64C25/46
Filed: 1948-12-11
Abstract: Un sistema de frenos accionado por presión de fluido para aviones cuyas ruedas están montadas en óleo-puntales provisto de medio para que el aumento de la presión interna en las patas ofrezca una fuente de presión para la aplicación automática e independiente de los frenos que comprende medios para descargar dicha presión interna por la aplicación de presión desde una fuente independiente de presión de fluido.
Patent ES-187207-A1 (ES)
Title: Procedimiento para tenir fibras animales
Filed: 1949-02-24
Abstract: Procedimiento para teñir fibras animales el cual comprende la operación de teñir con una sal de éster del ácido sulfúrico de un leucocolorante de tina con un baño tintóreo neutro a debilmente alcalino y el desarrollo del tinte resultante por oxidación.
Patent ES-190106-A1 (ES)
Title: PERFECCIONAMIENTOS EN LA FABRICACIoN DE ALPARGATAS
Filed: 1949-10-20
Abstract: Perfeccionamientos en la fabricación de alpargatas preferentemente alpargatas de dos o más suelas caracterizado por el hecho de preparar dos o más suelas independientes y acoplarlas entre sí por superposición sin cosido vertical que las una haciendo la trabazón entre ambas suelas y el corte por la especial disposición de éste que se prolonga por todo el contorno de dichas suelas a manera de faldón · proporcionado por el talón y el empeine del mismo cuyo faldón se cose transversalmente por puntada horizontal para cada una de las suelas de tal manera que en una sola operación resulte cosido el cerco exterior el corte o faldón y cada una de las suelas.
Patent ES-197893-A1 (ES)
Title: UN PERFECCIONAMIENTO EN LA FABRICACIoN DE LáMPARAS ELÉCTRICAS DE INCANDESCENCIA
Filed: 1951-05-09
Abstract: Perfeccionamiento en la fabricación de lámparas eléctricas de incandescencia que consiste esencialmente en formar una ampolla monopieza totalmente de vidrio transparente y depositar sobre los puntos convenientes de la superficie de la misma una o más capas de pintura cerámica vitrificable constituída a base de polvos de cristal en suspensión en medio fluido líquido o pastoso cuya capa puede formarse por simple inmersión pintado o proyección a pistola siendo la misma totalmente opaca u opal y susceptible de formar y recibir textos o gráficos y obteniéndose la fijación y necesaria solidificación de la misma mediante la acción de calor para lo cual se introduce la lámpara en un horno adecuado para la vitrificación del material cerámico que constituye el revestimiento.