baber/WOPTO huggingface dataset:
Patent DO-P2009000214-A (DO)
Title: Macrolidos basados en eritromicina
Inventor: NOE MARK CARL
Filed: 2009-09-08
Abstract: La invención se refiere a compuestos de formula (I) En la que R1, R2, y X son como se definen en el presente documento. La invención también se refiere a composiciones farmacéuticas y procedimientos de tratamiento de infecciones bacterianas usando los compuestos de formula (I)
Patent EC-SP12012098-A (EC)
Title: Derivados de arilmetoxi isoindolina y composiciones que los comprenden y métodos para utilizar los mismos
Inventor: CHEN ROGER
IPC: C07D417/14
Filed: 2012-08-09
Abstract: La invención se refiere a compuestos de fórmula: en la que: R es hidrógeno o alquilo inferior,R1 es -(CH2)n-(O)o-heterocicloalquilo o -C(O)-heterocicloalquilo, en el que el grupo heterociclolaquilo se sustituye opcionalmente con alquilo inferior, hidroxi, halógeno o con -(CH2)p-arilo, n es 0, 1 ó 2,o es 0 ó 1,p es 0, 1 ó 2,R2 es CF3, cicloalquilo, opcionalmente sustituido con alcoxi inferior o halógeno, o es indan-2-ilo, o es heterocicloalquilo, opcionalmente sustituido con heteroarilo, o es arilo o heteroarilo, en los que los anillos aromáticos se sustituyen opcionalmente con uno o dos sustituyentes, seleccionados de entre alquilo inferior, halógeno, heteroarilo, hidroxi, CF3, OCF3, OCH2CF3, OCH2-cicloalquilo, OCH2C(CH2OH)(CH2Cl)(CH3), S-alquilo inferior, alcoxi inferior, CH2-alcoxi inferior, alquinilo inferior o ciano, o con -C(O)-fenilo, -O-fenilo, -O-CH2-fenilo, fenilo o -CH2-fenilo, y en los que los anillos fenilo opcionalmente pueden sustituirse con halógeno, -C(O)-alquilo inferior, -C(O)-OH o -C(O)-O-alquilo inferior, o los anillos aromáticos se sustituyen opcionalmente con heterocicloalquilo, OCH2-oxetán-3-ilo o O-tetrahidropirán-4-ilo, opcionalmente sustituidos con alquilo inferior,X es un enlace, -NR'-, -CH2NH-, -CHR''-, -(CHR'')q-O-, -O-(CHR'')q- o -(CH2)2-, Y es un enlace o -CH2-R' es hidrógeno o alquilo inferior, R'' es hidrógeno, alquilo inferior, CF3, alcoxi inferior, q es 0, 1, 2 ó 3,o a una sal de adición de ácido farmacéuticamente aceptable de los mismos. Ahora se ha encontrado que los compuestos de fórmula I presentan una buena afinidad con los receptores asociados a rastros de aminas (TAARs), especialmente con TAAR1. Los compuestos pueden utilizarse para el tratamiento de la depresión, los trastornos de ansiedad, el trastorno bipolar, el trastorno de hiperactividad por déficit de atención (ADHD), los trastornos relacionados con el estrés, los trastornos psicóticos tales como la esquizofrenia, las enfermedades neurológicas tales como la enfermedad de Parkinson, los trastornos neurodegenerativos tales como la enfermedad de Alzheimer, la epilepsia, la migraña, la hipertensión, el abuso de sustancias, y trastornos metabólicos tales como trastornos de la alimentación, la diabetes, las complicaciones diabéticas, la obesidad, la dislipemia, los trastornos del consumo y asimilación de la energía, los trastornos y disfunción de la homeostasis de la temperatura corporal, los trastornos del sueño y del ritmo circadiano, y los trastornos cardiovasculares.
Patent EC-SP13012482-A (EC)
Title: Derivados de 5-yodo-triazol
Inventor: WACHENDORFF-NEUMANN ULRIKE
IPC: C07D405/06
Filed: 2013-03-07
Abstract: La presente invención se refiere a nuevos derivados de 5-yodo-triazol, a procedimientos para la preparación de estos compuestos, a agentes que contienen estos compuestos y a su uso como compuestos biológicamente activos, en particular para combatir microorganismos perjudiciales en fitoprotección y en protección de materiales y como reguladores del crecimiento de las plantas.
Patent EE-200200231-A (EE)
Inventor: MAEYRAE-MAEKINEN ANNIKA
IPC: A23L1/305
Filed: 2000-10-30
Abstract: The invention relates to a process for preparing a product containing antihypertensive peptides by fermenting a casein-containing starting material with lactic acid bacteria. The invention also relates to the obtained product and its use as a functional product as such or as an ingredient or additive of edible substances.
Patent GB-189703935-A (GB)
Title: Improvements in Means for Ornamenting Cigarette Cases and the like.
Inventor: WRIGHT WILLIAM FREDERICK
Filed: 1897-02-13
Granted: 1897-12-24
Abstract: 3935. Wright, W. F. Feb. 13. Ornamenting metal surfaces.-Cigarette, cigar, and photograph cases and boxes and like articles A of silver or other metal are ornamented by soldering strips or wires of gold or other metal B upon the surface to form any desired decorative design.
Patent GB-189705518-A (GB)
Title: An Improved Apparatus for Tying and Building Scaffolding.
Inventor: RYAN FRANCIS JOHN
Filed: 1897-03-02
Granted: 1897-12-18
Abstract: 5518. Ryan, F. J., Ryan, F. J., and Ryan, A.D. March 2. Scaffolding.- The poles 1,2 are secured together by chains c', d which are looped over bent hooks a<1> fixed to a plate a. The tying - chain d is connected by a ring to one of the hooks a', is passed over a hook c at the end of the forked chain c<1>, and after passing it round the poles is fastened by a hook at the end engaging with one of the links of the chain. A separate chain may be used to tie the hooked plate a to the pole 1, and double bracing chains may be used to tie the poles together. Instead of fixing the hooks a<1> to a single plate, two plates carrying the hooks may be connected by chains as shown in Fig. 2.
Patent GB-189709586-A (GB)
Title: Improvements in Current Collecting Apparatus for Electric Tramways.
Inventor: LITTLE CHARLES WILLIAM GODSON
Filed: 1897-04-15
Granted: 1898-02-19
Abstract: 9586. Little, C. W. G., and Ireland, A. J. April 15. Electric railways and tramways with overhead conductors. Collectors.-The springs which press the pole up to its work are contained within the standard. The pole socket d is hinged on an arm c<3> on the swivelling head C, which runs on ball bearings c, c<2> on the standard A. Two or more helical springs F attached to the head C carry a plunger B with adjustable head b which bears under rollers d<3> attached to the pole. The conductor G is led down through the plunger B. Stops i, i<2> prevent complete rotation of the head, but in a modified form this rotation is allowed by a swivelling joint in the conductor. This consists of an insulated extension of the lower part of the plunger working in an insulated ring inside the standard, these two parts being connected to the two ends of the conductor.
Patent GB-189712750-A (GB)
Title: Improvements in Carriages for Ordnance and Machine Guns.
Inventor: MURRAY ARCHIBALD CAMPBELL
Filed: 1897-05-24
Granted: 1898-04-02
Abstract: 12,750. Murray, A. C., and Murray, T. R. May 24. Drawings to Specifications. Disc wheels; hubs; felloes or rims.-Wheels for field-gun carriages are covered on their outer sides with metal discs to form shields. The disc may be flanged to form the rim and hub of the wheel.
Patent GB-189723906-A (GB)
Title: Improvements in Devices for Attaching Veils.
Inventor: ROSENBERG GUSTAV
Filed: 1897-10-16
Granted: 1897-11-20
Abstract: 23,906. Rosenberg, G. Oct. 16. Clip or clamp fastenings.-Veils are fastened by means of a clip or clamp consisting of two spring hinged pieces a, b, which can be held together by a catch k, thus gripping the veil. One of the pieces a is provided with an attachment pin n.
Patent GB-189726664-A (GB)
Title: Improvements in Apparatus for Cooling and Drying Air to be Used in Storage Chambers containing Perishable Produce.
Inventor: LORD FRANCIS WILLIAM
Filed: 1897-11-15
Granted: 1897-12-18
Abstract: 26,664. Lord, F. W. Nov. 15. Cooling air.-Air is cooled and dried for use in cooling-chambers by passing it through the parts a<1>, a<3> and pipes C in the box A, and then over pipes L in the box N. A cooling-agent is circulated round the pipes C, and a heating-agent is passed through the pipes L. Condensed moisture in the first part of the apparatus is drained off by the pipes H, and the fog is dissipated in the second or drying apparatus.
Patent GB-189727741-A (GB)
Title: Improved Grinding and Polishing Machinery, and Lap Wheels to be used therewith.
Inventor: BULL GEORGE FREDERICK
Filed: 1897-11-25
Granted: 1898-10-01
Abstract: 27,741. Bull, G. F. Nov. 25. Surfacing and polishing.-Relates to a machine for grinding and polishing small articles. The machine is described as used for operating upon the ends of the pins of cycle and like chains prior to riveting. A pair of grinding-discs c, d are mounted on shafts c<2>, d<2>, revolving in headstocks c<3>, d<3>, which are set at a slight inclination so as to bring the discs nearer together at the bottom. The chain is fed between the discs by a chainwheel g on a shaft which is revolved by a wormwheel and screw g<4>. Each disc is dished so as to leave only a ring of grinding-surface, and the pins pass inwards across the ring at the top and out at the bottom, where the space is narrower, being first ground and softened and then polished. The softening facilitates subsequent riveting.
Patent GB-189728713-A (GB)
Title: Improvements in Lubricating the Axles of Pit Tubs or Wagons.
Inventor: THOMPSON WILLIAM
Filed: 1897-12-04
Granted: 1898-03-05
Abstract: 28,713. Thompson, W. Dec. 4. Corves; axle-boxes, lubricating.-Tanks are secured underneath the body on each side and communicate with chambers d having openings to the bearing-surfaces. A cup f surrounds the lower part of each bearing to prevent waste. Pipes with screw cups are provided for filling the tanks.
Patent GB-189801714-A (GB)
Title: Improvements in Ventilators for the Chimneys of Incandescent Gas and similar Lamps.
Inventor: HOERNER WILHELM
Filed: 1898-01-21
Granted: 1899-01-14
Abstract: 1714. H÷rner, W. Jan. 21. Smut-catchers for incandescent and similar gas lamps. A hollow ring a, having a perforated gallery c supported on a chimney by projections d, carries an incombustible protecting-plate b movably supported by depending carriers e. The circulation of air and gas is ensured by the perforations in the gallery c and the hollow in the ring a. Small perforations may be provided in the plate b, which plate may also serve as a support for an automatic igniting-device.
Patent GB-189811872-A (GB)
Title: Improvements in or connected with Gloves.
Inventor: BOSSCHE PROSPER VAN DEN
Filed: 1898-05-25
Granted: 1898-07-09
Abstract: 11,872. Bossche, P. van den. May 25. G l o v e s.-T h e buttonhole slit i s cut with the upper end A inclined towards the thumb. The object is t o strengthen t h e glove and render it more supple t h a n usual.
Patent GB-189815118-A (GB)
Title: Protective Device for Incandescent Electric Lamps.
Inventor: KAES RICHARD
Filed: 1898-07-09
Granted: 1899-06-17
Abstract: 15,118. Kõs, R. July 9. Miners' and like safety lamps; globe holders. - Electric incandescent lamps for use in explosive atmospheres, by miners or others, are mounted so that pressure on globes enclosing them disconnects them electrically. The lamp q is supported in a globe x and in front of a reflector n by three hooked wires c<1>, p. The wire p is carried by the reflector, which is screwed on a ring b fixed on a backplate a. The globe x is carried by rings s, i, r, loose on the ring b, so that they can be moved backward a small distance, against the pressure of four wire springs, which are carried by the ring b and bear against parts of the ring i. A cross-bar k on the ring i extends through slots in the ring b. Electric connection to the lamp is effected by a switch e, pivoted on a connecting-plate d, and pressed towards a fixed contact c<3> by a wire spring. The switch is shown as held away from the contact by the interposition of a sliding stop f, which is pressed upward by a spring. The lamp is put in circuit by pulling down the stop f, which then releases the switch e; but, if the globe is pressed backward, the cross-bar k opens the switch, allowing the stop f to be again interposed by its spring. In a modification, the sliding stop f is not accessible from outside the globe, so that it cannot be withdrawn after the switch e has once been opened ; a separate sliding switch is also provided.
Patent GB-189819263-A (GB)
Title: Improvements in Means for Moistening and Affixing Postage Stamps.
Inventor: DIENZ ADAM GEORG
Filed: 1898-09-09
Granted: 1898-10-29
Abstract: 19,263. Dienz, A. G. Sept. 9. Damping and affixing stamps.- A sheet of stamps is held between plates b, b<1> on a table a, the plates being held together by a pivoted bar c and a spring b<2>. The top row of stamps lies under a guide a<2>, and the corner stamp, ready to be damped and detached, lies above a depression e in which there is a piece of cloth e<2> dipping in a water reservoir m. The stamp is detached and affixed by a carrier s, shown in section in Fig. 5 and in plan from below in Fig. 6. The pad s<2> presses the stamp down on the moistening - pad, and severs it from the sheet ; the needles t help to lift it. The next stamp on the sheet is held by a spring push o<1>, and the plate b<1> by a similar push q<1>. The sheet of stamps is automatically moved along to bring the next stamp above the space e when the carrier is lifted, the plates band b<1> being pulled towards the right by a piece of elastic r<1> and held in place by a ratchet d and catch g, which are released each time a stamp is taken by the carrier.
Patent GB-189821444-A (GB)
Title: Improvements in and relating to Brakes.
Inventor: HOFMANN CARL
Filed: 1898-10-12
Granted: 1898-11-12
Abstract: 21,444. Hofmann, C. Oct. 12. Brakes for b i - cycles, vehicles, &c., locking. The brake rod c passes down between a pair of bearings d pivoted at e on a bracket b. The bearings are each formed with two tapering races for balls g, and at their lower, c a m - shaped, ends are embraced by an eccentric ring i provided with handles. By turning these, the bearings are pressed together and the balls brought into contact with the rod, which is then locked as regards upward movement.
Patent GB-189821663-A (GB)
Title: A New or Improved Process for Tanning Rabbit and other Skins.
Inventor: PLANCKAERT JEAN LOUIS
Filed: 1898-10-14
Granted: 1898-12-03
Abstract: 21,663. Planckaert, J. L., and Vuylsteke, F. Oct. 14. Tanning.-Rabbit and other skins to be tanned are de-haired, washed, and soaked for 24 hours in an extract of gall nuts, sumach, red catechu, yellow catechu, turmeric, yellow wood (fustic), and quebracho. The subsequent processes of drying, "raising," glazing, and smoothing are of the usual character.
Patent GB-189826310-A (GB)
Title: Improvements in Junction Boxes, Switches, Wall Plugs and Distribution Boards for use in Electric Wiring.
Inventor: CLARK GEORGE ALEXANDER
Filed: 1898-12-13
Granted: 1899-07-22
Abstract: 26,310. Clark, G. A., McAulay, W., and McLaren, J. A. Dec. 13. Supporting lamps. -The cases of wall and ceiling roses may be of metal and provided with sweating boxes, or may be of insulating - material, when sweating boxes are not required. Fig. 11<a> shows a section through a wall rose, the conductors being soldered to branch pins D<1>, which pass through an insulated block C<1> and are recessed to form sockets for the plugs E<2> on the ends of the branch wires. A fibrous disc F grips the wires, and is held in place by a screw cap G. An insulating-nozzle may be screwed into the cap G. The arrangements of the parts are varied to suit different circumstances. When used to support an electrolier, the tube is passed through the cover of the rose, and provided with a curved disc to carry the weight. For an arc lamp, the pins D<1> are socketed at each end, the leads being sweated into the sockets after passing down through a divided insulating-disc. In the case of some wall sockets, the casing is extended backwards to form sweating-chambers such as are described in Specification No. 2263, A.D. 1885, [Abridgment Class, Electricity, Conducting &c.], and the contactsupporting disc is provided with a suitable metal cover.
Patent GB-189902174-A (GB)
Title: An Improvement in Commutator Brushes for Electrical Machines.
Filed: 1899-01-31
Granted: 1899-04-01
Abstract: 2174. Siemens Bros. & Co. and Siemens, A. Jan. 31. Brushes and brush-holders.-A metal strip b, having semicircular recesses at intervals, is fixed parallel to a support a by bolts and distance-pieces d at the ends, as shown in plan in Fig. 3. The support a is made with conductor holding bosses m at both ends, either of which may be used. The brushes e are placed in holders consisting of plates f, which slide into grooves in the front strip b, and springs q, which bear against the support a. The holders are pressed down by springs i hooked on them at k. The brushes may be lowered in the holders by screws h. The springs g may be bent to engage notches in the support a, to hold the brushes up. The holders may be removed, the spring plates j being then kept in place by notches l.
Patent GB-189903103-A (GB)
Title: Improvements in and relating to Letters, Numerals, and Signs for Advertising and Display Purposes.
Inventor: GUEST GEORGE
Filed: 1899-02-11
Granted: 1899-12-16
Abstract: 3103. Guest, G. Feb. 11 Letters and numerals; signs.-Letters, numerals, and signs are formed, in front, of sections B of glass or other material which rest at the base in grooves G in a background, and at the top on pegs D, being secured by pins C, the front thus formed presenting a series of a pyramidal or side projections.
Patent GB-189905113-A (GB)
Title: Improvements in and relating to the Drying of Fish and other Substances.
Inventor: SMETHURST HENRY
Filed: 1899-03-08
Granted: 1900-01-06
Abstract: 5113. Smethurst, H. March 8. Drying-kilns.-A kiln for drying fish &c. is shown in plan in Fig. 1 and in elevation in Fig. 2. Two drying-chambers A, A' have a fireplace C placed between them, and the hot gases circulate round flues B to a central chimney D, so that the air in the air passages E is heated. The air passages heat the contents of the drying-chambers, which can be used alternately or together. The air in the drying-chambers is caused to circulate by a fan G, or by providing suitable openings H in the walls.
Patent GB-189912065-A (GB)
Title: Improvements in Brake Apparatus for Railway Wagons or like Vehicles.
Inventor: SWIFT THOMAS DICKENSON
Filed: 1899-06-09
Granted: 1900-04-21
Abstract: 12,065. Swift, T. D. June 9. Brakes, hand-power. Relates to means for applying the brakes from either side of a wagon or like vehicle. The transverse shafts D, D', provided at each end with handles E, E', are cranked at J, J<1> and connected by the rod K. The lever G is forced downwards to apply the brakes by means of links H and cranks F attached to the handles E, which are turned outwards. Springs, not shown, may be fitted to the cranked portion of the shaft D, or to discs on it, to maintain the brakes in position at about half the maximum pressure. The Provisional Specification describes modifications in which the brake lever G has ratchet teeth gearing with a toothed segment pivoted eccentrically on the shaft D, or the lever is slotted to receive a crank on an auxiliary hand-lever or on the shaft D.
Patent GB-189912786-A (GB)
Title: Improvements in Machinery for Setting Heel and Sole Protectors for Boots and Shoes.
Inventor: THOMPSON WILLIAM PHILLIPS
Filed: 1899-06-19
Granted: 1900-06-02
Abstract: 12,786. Thompson, W. P., [Whitcher, F. W., and Winter, H. W.]. June 19. Sole and heel protectors.-Relates to machines for inserting protectors of the horse-shoe form, shown in Figs. 14 and 15, either singly or in groups. The machine shown is arranged to insert a group into a top-lift before it is attached to the heel, but by modifying the work-support it can be used to insert them into finished heels or soles. The main spindle B of the machine is driven from a loose pulley through a " Horton " clutch C, which is automatically thrown out of gear after the spindle has made one revolution, even although the starting- treadle is held in the depressed position. A certain amount of lostmotion is provided between the clutch and the treadle, the initial movement of which is used to move the worksupport into the operative position shown in dotted lines in Fig. 1. The lift to be operated on rests between guides on a clamp H<5>, which is placed in one of two positions according to whether the lift is for a right or left shoe. The clamp rests on a spindle W, which is screwed into a plunger W<4> vertically movable in the sliding carriage W<5>. This carriage is moved in one direction by the treadle through a bell crank W<6>, and is returned by a spring. When in the operative position, the plunger is over a cam w<6> and is raised by the said cam, which is rotated by the descent of the plunger B<5> carrying the drivers. The protectors are contained in a hopper H the barrel of which is rotated in ball bearings between the end plates. Projections on the interior of the barrel lift the protectors and drop them on to a receiver F, Fig. 17, between the vertical members of which projections E<1> on a carrier E are moved up and down. The protectors straddle these projections, and slip off them on to the raceways R, by which they are led to the feeding and driving mechanism. The protectors on each raceway are passed one at a time by a detent, carried by a reciprocating plate M, to a selecting-device carried by a second reciprocating plate N. This device throws back into the hopper the protectors which are presented wrong end first. Those presented right way on pass to a device carried by a reciprocating plate 0, and, if the lower portion of the raceway is free, are returned to the hopper. Each raceway turns through 180‹ to reverse the protectors, which pass one at a time to a movable continuation t, which is reciprocated horizontally to bring them under the drivers. The driving-plunger B<5> is reciprocated by a crank on the main spindle B.
Patent GB-189917168-A (GB)
Title: Band Saw for Sawing Metals.
Inventor: HARTMANN WILHELM
Filed: 1899-08-24
Granted: 1899-11-11
Abstract: 17,168. Hartmann, W. Aug. 24. Sawing.-Relates to a band-sawing machine for sawing metal, in which the saw is fed forward, the metal remaining fixed. As shown in the plan, Fig. 3, the band saw a runs over three pulleys b, c and another pulley (not shown) vertically below c. The axes of these pulleys are simultaneously pushed forwards longitudinally by a weight n. This weight, acting through a strap n<1>, turns the shaft o, which by means of a fork acting on the studs r' pushes forward the shaft q of the pulley b. The movement is communicated to the shafts p of the pulleys c by levers k geared together by toothed segments l. Modifications of this feedmechanism are described in which levers alone are used, the toothed segments being dispensed with. Hollow pulleys for the saw, stamped out of sheet metal and with longitudinal spring supports, are described.
Patent GB-190004309-A (GB)
Title: An Improved Method of Making Fire-proof Pulp for use in the Manufacture of Boards and other Articles.
Inventor: KEYES FRANK EUGENE
Filed: 1900-03-06
Granted: 1900-12-01
Abstract: 4309. Keyes, F. E. March 6. Wet grinding.-In the grinding of wood for pulp, a suitable fireproofing-liquid, such as a mixture of sulphate and phosphate of ammonia, is used instead of pure water, the pulp being subsequently screened and passed to suitable apparatus, by which it is formed into sheets or other articies. By the use of this invention the operations of drying and re-beating the pulp are avoided.
Patent GB-190004340-A (GB)
Title: An Improved Construction in connection with the Anti-friction Mechanism of the Axle Shafts of Railway Carriages and other Vehicles.
Inventor: COOPER JOHN EDWARD
Filed: 1900-03-07
Granted: 1901-06-07
Abstract: 4340. Cooper, J. E. March 7 A x l e bearings ; springs, bearing.- Relates to means for combining the bearing springs with axle e antifriction apparatus of the type described in Specification No. 19,579, A.D. 1897 [Abridgment Class Wheels &c.]. The spring b, attached to the box c<1> of the cranked axle c of an omnibus or other vehicle, is free to move between the members a<1> of the hornplates or guides. The disc e, loose on the axle c, bears against the roller f from the main axle d.