baber/WOPTO huggingface dataset:
Patent NZ-524129-A (NZ)
Title: Mixed-mode interaction
Inventor: MAMDANI MALIK
IPC: G06Q20/40
Filed: 2000-11-15
Abstract: A user of a wireless device, such as a mobile phone, can make purchases or obtain information via a network, such as the Internet, using both voice and non-verbal methods. Users can submit voice queries and receive non-verbal replies, submit non-verbal queries and receive voice replies, or perform similar operations that marry the voice and data capabilities of modern mobile communication devices. A first spoken input is received from a wireless communication device in a first communication session. The input includes purchase notification criteria indicating at least one condition upon which the wireless communication device is to receive a purchase opportunity notification. The condition is unrelated to price. The location of the wireless communication device is determined using a location services function. The currently available purchase opportunity information associated with the first spoken input is retrieved, and the match information is selected from the retrieved information. The match information is based at least in part on the condition of the purchase notification criteria and the determined location. A non-verbal response to the first spoken input is delivered in a second communication session, to the wireless communication device. The non-verbal response is based on the selected match information. A second spoken input is received from the device for accessing a voice wallet. The voice wallet authorizes a purchase transaction upon the second spoken input being authenticated by the voice wallet.
Patent NZ-525400-A (NZ)
Title: A process for making gypsum board having improved through-penetration strength
Inventor: PETERSON KURT N
IPC: B28B19/00
Filed: 2001-09-17
Abstract: A process for making gypsum board comprising: feeding a paper backing sheet and a fibreglass or plastic woven or non-woven scrim material in alignment to a board forming station, separating the paper and the scrim, feeding a high density calcium sulphate hemihydrate slurry into the trough formed between the paper and the scrim, and subsequently compressing the paper and the scrim into contact whereby the high density slurry is forced through the scrim, completely encapsulating the scrim in the high density slurry. As a result of this process, excellent bond is developed between the paper, the high density gypsum layer and the foamed gypsum core. The gypsum board has improved through-penetration strength.
Patent NZ-526562-A (NZ)
Title: 1,5 benzothiazepines and their use as antihyperlipidemics
Inventor: STARKE INGEMAR
IPC: A61K31/675
Filed: 2001-12-17
Abstract: 1,5 benzothiazepine compounds of the formula (I), their pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia are disclosed, wherein one of R4 and R5 is a group of formula (IA), the other variable groups shown in the formulae (I) & (IA) are as defined in the specification. Processes for their manufacture and pharmaceutical compositions containing them are also disclosed.
Patent NZ-528874-A (NZ)
Title: Use of esters of L-carnitine or alkanoyl L-carnitines as cationic lipids for the intracellular delivery of pharmacologically active compounds
Inventor: PISANO CLAUDIO
IPC: A61K9/127
Filed: 2000-04-11
Abstract: Disclosed are liposome compositions comprising a liposome membrane, and a substance with cosmetic activity or a drug, wherein the liposome membrane comprises a compound of formula (II), wherein: R3 is an acyl chain, R4 is an alkyl chain, X- is an anion of a pharmacologically acceptable acid. (62) Divided out of 515270
Patent NZ-532885-A (NZ)
Title: Nasal administration of xylitol to a non-human mammal
Inventor: BOZEMAN JERRY J
IPC: A61K31/7004
Filed: 2004-05-12
Abstract: Disclosed herein is a method of reducing the occurrence of shipping fever in a non-human mammal such as cattle, wherein the method comprises administration of xylitol, preferably as a mist that is sprayed through the nasal path of the non-human mammal.
Patent NZ-533499-A (NZ)
Title: Surgical patches coated with biologically active agents to prevent adverse tissue reaction to the patch
Inventor: SIGNORE PIERRE E
IPC: A61L33/00
Filed: 2002-12-30
Abstract: Surgical patches which release an anti-inflammatory agent, an anti-platelet agent, an anticoagulant, a fibrinolytic agent, a cell-cycle inhibitor, and/or an anti-proliferative agent to prevent adverse tissue reaction to the patch.
Patent NZ-538490-A (NZ)
Title: 2-(3-aminoaryl)amino-4-aryl-thiazoles and their use as C-kit inhibitors
Inventor: CIUFOLINI MARCO
IPC: C07D277/56
Filed: 2003-07-31
Abstract: Disclosed is a 2-(3-aminoaryl)amino-4aryl-thiazole) of formula I wherein the substituents are as described in the specification. Compounds of the type disclosed are useful in the treatment of c-kit receptor mediated disorders in particular cell proliferative, metabolic, allergic and degenerative disorders.
Patent NZ-539708-A (NZ)
Title: Carboxylic acid derivative and salt thereof
Inventor: MATSUURA FUMIYOSHI
IPC: A61P1/04
Filed: 2002-04-18
Abstract: Disclosed are carboxylic acid compounds of formula (I), a salt thereof, an ester thereof or a hydrate of them, wherein: R1 represents a carboxyl group, an alkyl group or an alkoxy group; L represents a single bond, an alkylene group or an alkynylene which may have one or more substituents; M represents an alkylene group which may have one or more substituents; T represents a single bond, an alkylene group or an alkynylene group, each of which may have one or more substituents; W represents a carboxy group; X represents a group represented by -OCQ1NRX1- (wherein Q1 represents an oxygen atom; and RX1 represents a hydrogen atom or an alkyl group which may have one or more substituents); Y represents a 5- to 14-membered aromatic group or an alicyclic hydrocarbon group, each of which may have one or more substituents and one or more hetero atoms; and the ring Z represents a 5-to 14-membered aromatic group which may have 1 to 4 substituents and one or more hetero atoms, and wherein part of the ring may be saturated. (62) Divided out of 528655
Patent NZ-541391-A (NZ)
Title: Adaptive junk message filtering system
Inventor: ROUNTHWAITE ROBERT L
IPC: G06Q10/10
Filed: 2003-12-31
Abstract: A data filtering system comprises a first filter for filtering one or more messages and a second filter for filtering the messages. The first filter is associated with a false positive rate and a false negative rate and the second filter is evaluated based at least in part on the false positive rate and the false negative rate of the first filter. The data used to determine the false positive rate and the false negative rate of the first filter is utilized to determine a new false positive rate and a new false negative rate associated with the second filter as a function of threshold. The second filter is employed in lieu of the first filter upon a threshold where the new false positive rate and new false negative rate of the second filter together are considered better than the false positive and the false negative rate of the first filter.
Patent NZ-541415-A (NZ)
Title: Benzoazolylpiperazine derivatives having metabotropic glutamate receptor 1 and receptor 5 (mGluR1- and mGluR5-) antagonistic activity
Inventor: SUN QUN
IPC: C07D401/12
Filed: 2003-12-22
Abstract: Benzoazolylpiperazine derivatives and pharmaceutically acceptable salt thereof having metabotropic glutamate receptor 1 (mGluR1) and metabotropic glutamate receptor 5 (mGluR5-) antagonistic activity are disclosed, wherein these benzoazolylpiperazine compounds can be represented by formula (Ia), (IIb), (IIIa) etc., wherein Ar1, A, R3, x, and m are as defined in the specification. These benzoazolylpiperazine compounds are useful for inhibiting VR1 function in a cell and are suitable for treating or preventing pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, retricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia, or depression in an animal.
Patent NZ-546160-A (NZ)
Title: Amide type carboxamide derivatives
Inventor: KAWAGUCHI TAKAYUKI
IPC: A61P43/00
Filed: 2004-09-24
Abstract: The present disclosure relates to amide-type carboxamide derivatives of formula [1], wherein the variables shown in formula [1] are as defined in the specification, useful particularly as an inhibitor of activated blood coagulation factor X (FXa) in the treatment of diseases caused by thrombi and emboli.
Patent NZ-547225-A (NZ)
Title: Particle-forming compositions containing fused pyrrolocarbazoles
Inventor: DICKASON DAVE
IPC: A61K31/403
Filed: 2004-11-12
Abstract: Provided is a composition comprising a fused pyrrolocarbazole of the depicted formula, wherein R3 and R4 are selected from H, alkyl, CI, Br, CH2OH, CH2SOCH2CH3, CH2SO2CH2CH3, NHCONHC6H5, CH2SCH2CH3, CH2SC6H5, NHCO2CH3, CH2OC(=O) NHCH2CH3, N(CH3)2, CH=NNH, CH2N(CH3)2 and CH2OCH2CH3, R7 is selected from H and alkyl; and R15 and R16 are independently selected from H, alkyl, OH, CH2OH, alkoxy, and C(=O)Oalkyl; or a stereoisomer or pharmaceutically acceptable salt form thereof; at least 20% (w/w) of a polyoxylstearate; and at least one polyethylene glycol.
Patent NZ-549890-A (NZ)
Title: Sulphonamide derivatives as inhibitors for collagen receptor integrins
Inventor: SMITH DAVID
IPC: C07D277/64
Filed: 2004-07-12
Abstract: Sulphonamide derivatives of formula (I) are disclosed, wherein RC is optionally substituted 4-6-membered heterocyclic ring containing one or more N atoms, or RC forms together with the phenyl ring to which it is attached a benzodioxolyl group, or RC is -NR1R2; RA is a group having the formula (A), (B) or (C); and RB is hydrogen or alkyl, wherein the remaining variables are as defined in the specification. The disclosure also relates to the use of derivatives of formula (I) as inhibitors for collagen receptor integrins and a process for preparing sulphonamides of formula (I).
Patent NZ-553825-A (NZ)
Title: Ergonomic and adjustable respiratory mask assembly
Inventor: GING ANTHONY
IPC: A61M16/08
Filed: 2003-04-17
Abstract: A nasal mask assembly for nasal CPAP therapy, comprising: a mask frame; a silicone nasal seal which can be repeatedly detached from and reattached to the frame; an elbow rotatably coupled to the frame and adapted to connect to a gas delivery tube; and a headgear assembly to secure the frame and nasal seal to a patient's head. The headgear assembly includes a pair of relatively flexible, Y-shaped straps (84) having a relatively soft fabric and foam material construction, and a stiffening layer (92) made of a relatively rigid material compared to the strap material. The stiffening layer is attached to an outside surface of the pair of straps resting against the cheek regions in use. The stiffening layer is narrower than the strap portion.
Patent NZ-560359-A (NZ)
Title: Anti-T cell and autoantigen treatment of autoimmune disease using CD3 monoclonal antibodies and glutamic acid decarboxylase, insulin, beta cell protein or a combination thereof.
Inventor: JEVNIKAR ANTHONY
IPC: A61K31/519
Filed: 2006-02-06
Abstract: Discloses the use of: (a) an anti-T cell therapy, wherein said anti-T cell therapy comprises at least one immunosuppressant agent that targets T cells, most preferably an anti CD3 monoclonal antibody; and (b) an autoantigen composition comprising an immunoregulatory cytokine, wherein said autoantigen is a glutamic acid decarboxylase (GAD), insulin, a beta cell protein, or a combination thereof; in the manufacture of a medicament for the treatment of new onset Type I diabetes in a mammal or a pre-Type I diabetic mammal, wherein (a) and (b) are concurrently or sequentially administrable.
Patent NZ-562663-A (NZ)
Title: Novel vaccine formulations
Inventor: PARISOT ALEXIS GUY ANDRE
IPC: A61K39/02
Filed: 2006-04-13
Abstract: Disclosed is an oil-in -water (O/W) emulsion comprising: (1) an aqueous solution containing a vaccine antigen or immunogen capable of inducing an immune response in a host; (2) A non-ionic lipophilic ethoxylated fatty alcohol; (3) A mineral oil; (4) A non-ionic hydrophilic surfactant which is an ethoxylated fatty alcohol.
Patent NZ-568015-A (NZ)
Title: Human monoclonal antibodies to O8E
Inventor: KORMAN ALAN J
IPC: A61P35/00
Filed: 2006-12-08
Abstract: Disclosed are human monoclonal antibodies that bind specifically to human O8E (also known as VTCN1). The antibodies can be used as therapeutic agents to treat tumours overexpressing O8E.
Patent NZ-568403-A (NZ)
Title: CD20-specific antibodies and methods of employing same
Inventor: TEDDER THOMAS F
IPC: C07K16/28
Filed: 2004-05-07
Abstract: Disclosed is a monoclonal antibody (mAb) or antigen-binding fragment thereof that specifically binds to CD20 wherein said antibody has a treatment effective dosage range of 125 mg/m2 or less that results in at least a 75% depletion in circulating B cells, tissue B cells, or both, in a subject, wherein the mAb or antigen-binding fragment thereof comprises heavy chain CDR1, CDR2, and CDR3 or light chain CDR1, CDR2, and CDR3 from a mAb produced by a hybridoma selected from the group consisting of HB20-3, HB20-4, and HB20-25 with 5 or fewer amino acid substitutions, deletions, or insertions.
Patent NZ-577243-A (NZ)
Title: Isoxazolidine derivatives for inhibiting the interaction of bcl proteins with binding partners
Inventor: CASTRO ALFREDO C
IPC: C07D413/12
Filed: 2007-11-14
Abstract: Disclosed are isoxazolidine compounds that bid to Bcl proteins and block Bcl anti-apoptotic function in cancer cells and tumour tissue expressing the Bcl protein.
Patent NZ-579645-A (NZ)
Title: Pyrazolo (3, 4-b) pyridine derivatives as phosphodiesterase inhibitors
Inventor: RUDRA SONALI
IPC: C07D519/00
Filed: 2008-03-14
Abstract: Disclosed are compounds of general Formula I where M and R1-R3 are as defined in the claims. The compounds are phosphodiesterase (PDE) type 4 PDE type 7 and dual PDE type 4/PDE type 7 inhibitors. Examples of the disclosed compounds include: N-cyclohexyl-1-ethyl-5-(1-oxa-2-azaspiro[4,4]non-2-en-3-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine; and 4-{ [1-Ethyl-5-(5-oxa-6-azaspiro[3,4]oct-6-en-7-yl)-1H-pyrazolo[3,4-b]pyridin-4-yl] amino} cyclohexanol. Further disclosed is a method for the preparation of compounds of Formula I, a pharmaceutical composition comprising a therapeutically effective amount of the compounds, and the use of the compounds in the manufacture of a medicament for the treatment or prevention of multiple sclerosis, AIDS, transplant rejection, rheumatoid arthritis, bronchitis, chronic obstructive pulmonary disease (COPD), asthma, psoriasis, allergic rhinitis, shock, atopic dermatitis, Crohn's disease, adult respiratory distress syndrome (ARDS), eosinophillic granuloma, allergic conjunctivitis, osteoarthritis, colitis, pancreatitis and cancer in a mammal.
Patent NZ-582528-A (NZ)
Title: Damping system with pressure relief sending oil back to the main cylinder on maximum extension of the fork
Inventor: UCHIYAMA MIKIO
IPC: B60G3/01
Filed: 2010-01-12
Abstract: A front fork for a motor vehicle is disclosed. During the process of absorbing variation in ground height with respect to the vehicle, oil has the tendency to pass from one reservoir (43A) to the other (43B) increasing the stiffness of the fork. An oil bypass is provided in the piston rod (22) which, at a pre-set extension of the fork, connects the two oil reservoirs to equalise the pressure. A number of ways to implement the bypass are disclosed.
Patent NZ-589830-A (NZ)
Title: Non disintegrating nozzle protector blow off cap
Inventor: MORGAN SEAN
IPC: A62C31/02
Filed: 2009-05-22
Abstract: 589830 Disclosed is a blow off protective cap for maintaining the aperture of a fire sprinkler nozzle. The nozzle has a tip with an aperture covered with a sealing membrane held in position over the nozzle aperture by a cap which is attachable to the nozzle by screw means, the sealing membrane preventing ingress of contaminants into the nozzle aperture when not in use. The sealing membrane becomes dislodged from the nozzle when use of the nozzle commences by pressure building up behind the sealing membrane and within the nozzle to cause the sealing membrane to deform, allowing the sealing membrane to blow away from the nozzle, and the sealing membrane does not disintegrate. The cap has a stepped lip that cooperates with the nozzle tip to form a gap in which the sealing membrane can be retained. The cap is attachable to the nozzle by screw means once the sealing membrane is placed over the nozzle tip.
Patent NZ-595853-A (NZ)
Title: IMPROVED BIOMASS PRETREATMENT PROCESS- ligno-cellulosic biomass
Inventor: GARBERO MIRKO
IPC: C12P19/02
Filed: 2010-03-31
Abstract: Disclosed is a process for the treatment of ligno-cellulosic biomass comprising the steps of: A) soaking the ligno-cellulosic biomass in a low temperature soaking step in liquid comprised of water at a temperature in the range of 25 to 100°C for 1 minute to 24 hours and the low temperature soaking step is followed by a separation step to separate at least a portion of the liquid from the low temperature soaked ligno-cellulosic biomass; B) soaking the ligno-cellulosic biomass feedstock in vapor or liquid water or mixture thereof in the temperature range of 100 to 210°C for 1 minute to 24 hours to create a soaked biomass containing a dry content and a first liquid; C) separating at least a portion of the first liquid from the soaked biomass to create a first liquid stream and a first solid stream; wherein the first solid stream comprises the soaked biomass; D) steam exploding the first solid stream to create a steam exploded stream comprising solids and a second liquid.
Patent NZ-602137-A (NZ)
Title: Uv associated mtdna fusion transcripts and methods and uses thereof
Inventor: HARBOTTLE ANDREW
IPC: C12Q1/68
Filed: 2011-03-01
Abstract: Discloses an isolated mitochondrial fusion transcript associated with UV exposure, wherein the transcript comprises the nucleic acid sequence as set forth in SEQ ID NO: 39, wherein the sequence is defined in the complete specification.
Patent NZ-604583-A (NZ)
Title: Oral formulations of kinase inhibitors
Inventor: CHEN ANDREW XIAN
IPC: A61K31/535
Filed: 2011-06-28
Abstract: The disclosure is directed to formulations of bioactive compounds of limited water solubility, inhibitors of focal adhesion kinase (FAK) of the 2,4-diaminopyridine class, adapted for oral administration to patients. The formulations are self-emulsifying in the gastrointestinal tract of the patients, providing enhanced absorption and bioavailability of the bioactive compounds as dispersions or emulsions in an oil base. For example, esters of PEG-ylated glycerol can be used as the oil, in conjunction with surfactants such as lecithin and TEPG succinate and solubilizers such as PEG 400 to provide useful oral formulations for administration to patients having a malcondition wherein inhibition of FAK is medically indicated, such as cancer or arthritis.
Patent NZ-606093-A (NZ)
Title: Method and apparatus for production of flexible duct
Inventor: WILSON STEPHEN ROBERT
IPC: F16L59/153
Filed: 2008-12-24
Abstract: Disclosed is a method of forming a flexible duct that includes helically winding a tube containing insulating material, wherein the tube is delivered into its initial winding at a rate so that at the outer periphery of the winding of the tube remains substantially unstretched and uncompressed circumferentially, while at the inner periphery the tube is allowed to pucker circumferentially. The aforesaid rate of delivery may be achieved by engaging said outer periphery with at least one press wheel that drives the outer periphery onto a mandrel assembly that helically winds the tube to form the duct, the rates of rotation of the press wheel and mandrel assembly being synchronised so that at the outer periphery of the winding the tube remains substantially unstretched and uncompressed circumferentially, while at the inner periphery the tube is allowed to pucker circumferentially. Preferably, the method of the first aspect of the invention is utilised to form the second layer of a flexible described herein. To that end, the insulating material is preferably a mass of loose fibrous insulating material. Advantageously, the second layer is adhered to the first layer. Preferably, for enhanced flexibility of the duct, adjacent windings of the tube are not adhered together, although they are typically in contact.
Patent NZ-608142-A (NZ)
Title: Amatoxin-conjugates with improved linkers
Inventor: ANDERL JAN
IPC: A61P35/00
Filed: 2011-09-29
Abstract: The disclosure relates to conjugates of an amatoxin and a target-binding moiety, e.g. an antibody, connected by a linker comprising a urea moiety, which are useful in tumour therapy for the treatment of cancer selected from the group consisting of pancreatic cancer, cholangiocarcinoma, breast cancer, colorectal cancer, lung cancer, prostate cancer, ovarian cancer, stomach cancer, kidney cancer, malignant melanoma, leukemia, and malignant lymphoma. In a further aspect the disclosure relates to pharmaceutical compositions comprising such conjugates.
Patent NZ-608303-A (NZ)
Title: Interlocking building blocks
Inventor: MONTEITH STUART HAMILTON
IPC: E04B2/08
Filed: 2011-12-16
Abstract: 608303 A building block for retaining walls is typically of cuboid shape and has two slots 18, 19, in a bottom face, that are each parallel to front and rear faces. The block has two projections 16, 17 in the form of truncated cones that are in a straight line parallel to the front and rear faces and can inter-engage with the slots of an adjacent overlying block. The block may be used inverted and can be used either to have blocks flush or so as to have blocks in staggered vertical arrangement.
Patent NZ-701626-A (NZ)
Title: Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1
Inventor: FURET PASCAL
IPC: C07D403/10
Filed: 2013-05-09
Abstract: The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.
Patent NZ-710567-A (NZ)
Title: Antiviral compounds
Inventor: BACON ELIZABETH M
IPC: C07D513/04
Filed: 2011-11-16
Abstract: Provided are compounds of the general formula (I), where W1a is selected from 101-116, 125 and 130, and the other variables are as defined in the specification. Examples of the compounds include (S)-tert-butyl 2-(5-(4-(6-(2-((2S,4S)-4-hydroxy-1-((S)-2-(methoxycarbonylamino)-3-methylbutanoyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)naphthalen-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate and methyl { (2S)-1-[(2S,4S)-2-[5-(7-{ 2-[(2S,5S)-1-{ (2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl} -5-methylpyrrolidin-2-yl]-1H-imidazol-5-yl} -5,10-dihydrochromeno[5,4,3-cde]chromen-2-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl} carbamate. The compounds are inhibitors of hepatitis C virus (HCV).
Patent NZ-711543-A (NZ)
Title: Anti-cd83 antibodies and use thereof
Inventor: SELDON THERESE ANN
IPC: A61P37/08
Filed: 2014-01-31
Abstract: The present disclosure relates to proteins that bind to CD83, CD83 is a cell surface receptor up-regulated on dendritic cells during maturation/activation and can be used as a target for the treatment, prophylaxis, diagnosis, or prognosis of disorders relating to undesired maturation/activation of dendritic cells; such as, tissue rejection