baber/WOPTO huggingface dataset:
Patent CY-1113759-T1 (CY)
Title: Ταχεως διασπομενοι ανταγωνιστες υποδοχεα ντοπαμινης 2
Inventor: MACDONALD GREGOR JAMES
IPC: C07D237/20
Filed: 2012-10-30
Abstract: Η παρούσα εφεύρεση αφορά 4-αρυλ-6-πιπεραζιν-1-υλ-3-υποκατεστημένες-πυριδαζίνες οι οποίες είναι ταχέως διασπόμενοι ανταγωνιστές υποδοχέων ντοπαμίνης 2, διεργασίες για την παρασκευή αυτών των ενώσεων, φαρμακευτικές συνθέσεις που περιέχουν αυτές τις ενώσεις ως δραστικό συστατικό. Οι ενώσεις βρίσκουν χρησιμότητα ως φάρμακα για τη θεραπευτική αγωγή ή πρόληψη διαταραχών του κεντρικού νευρικού συστήματος, για παράδειγμα σχιζοφρένειας, ασκώντας μια αντιψυχωτική επίδραση, χωρίς κινητικές παρενέργειες.
Patent CY-1113736-T1 (CY)
Title: Ετεροαρυλ-ουριες και η χρηση τους ως ενεργοποιητες γλυκοκινασης
Inventor: MURRAY ANTHONY
IPC: A61K31/4168
Filed: 2013-02-06
Abstract: Η παρούσα εφεύρεση αναφέρεται σε ενώσεις που είναι τύπου (I) όπου το Α είναι ετεροαρύλιο και τα R1 και R2 είναι αμφότερα κυκλικά κατάλοιπα, τα οποία είναι ενεργοποιητές της γλυκοκινάσης και κατά συνέπεια μπορεί να είναι χρήσιμα στην αντιμετώπιση, αγωγή, έλεγχο ή επικουρική αγωγή των νόσων όπου η αυξανόμενη ενεργότητα της γλυκοκινάσης είναι ωφέλιμη.
Patent CY-1114929-T1 (CY)
Inventor: FRIEDL THOMAS DR
IPC: A61K31/635
Filed: 2013-02-15
Abstract: A bilayer pharmaceutical tablet for the treatment of hypertension compring a first layer formulated for immediate release of the angiotensin II receptor antagonist telmisartan from a dissolving tablet matrix which contains telmisartan in substantially amorphous form, and a second layer formulated for immediate release of a thiazide diuretic from a fast disintegrating tablet matrix.
Patent CY-1117126-T1 (CY)
Title: Σφαιριδια φορεα, μεθοδος για την παραγωγη τους και τη χρηση τους
Inventor: WEIGT ANTJE
IPC: A61K9/16
Filed: 2015-11-03
Abstract: Η εφεύρεση αναφέρεται σε μία μέθοδο για την παραγωγή σφαιριδίων φορέα για φαρμακευτικές δραστικές ουσίες. Ομοίως, η εφεύρεση αναφέρεται σε τέτοιου είδους σφαιρίδια φορέα καθώς και σε φαρμακευτικά σκευάσματα που τα περιέχουν. Σύμφωνα με την εφεύρεση χρησιμοποιούνται σφαιρίδια φορέα για τη μεταφορά και την αποδέσμευση φαρμακευτικών δραστικών ουσιών, ιδίως στο ανθρώπινο σώμα.
Patent CY-1118572-T1 (CY)
Title: Παραγωγο κυκλοαλκανιου
Inventor: SHINOZUKA TSUYOSHI
IPC: C07D417/12
Filed: 2017-01-31
Abstract: Παρεχόμενο είναι ένα φάρμακο για τη θεραπεία ή/και πρόληψη του πόνου ή ένα φάρμακο για τη θεραπεία και πρόληψη προκαλούμενων από δίαυλο νατρίου ασθενειών. Μία ένωση που αντιπροσωπεύεται από τον τύπο (I) ή φαρμακευτικώς αποδεκτό άλας αυτής: Ar1, Ar2: ετεροαρύλ ομάδα, αρύλ ομάδα· R1, R2, R3: άτομο υδρογόνου, άτομο αλογόνου, C1-C6 αλκύλ ομάδα, αλογονωμένη C1-C6 αλκύλ ομάδα, υδρόξυ C1-C6 αλκύλ ομάδα, C1-C6 αλκόξυ C1-C6 αλκύλ ομάδα ή C3-C7 κυκλοαλκύλ ομάδα, κύανο ομάδα· R4 και R5: άτομο υδρογόνου, άτομο αλογόνου, C1-C6 αλκύλ ομάδα, αλογονωμένη C1-C6 αλκύλ ομάδα, υδροξύλ ομάδα, υδρόξυ C1-C6 αλκύλ ομάδα, C1-C6 αλκόξυ C1-C6 αλκύλ ομάδα, C3-C7 κυκλοαλκύλ ομάδα, C1-C6 αλκόξυ ομάδα· n: ακέραιος από 1 έως 3· η ετεροαρύλ ομάδα και η αρύλ ομάδα μπορεί να έχουν μία ή δύο ομάδες επιλεγόμενες ανεξαρτήτως από άτομο αλογόνου, C1-C6 αλκύλ ομάδα, αλογονωμένη C1-C6 αλκύλ ομάδα, υδρόξυ ομάδα, υδρόξυ C1-C6 αλκύλ ομάδα, C1-C6 αλκόξυ C1-C6 αλκύλ ομάδα, C3-C7 κυκλοαλκύλ ομάδα, καρβόξυλ ομάδα, κύανο ομάδα, άμινο ομάδα, C1-C3 αλκυλάμινο ομάδα και δι-C1-C3 αλκυλάμινο ομάδα· στη δε περίπτωση των δύο, οι δύο μπορεί να είναι οι ίδιες ή διαφορετικές.
Patent CY-1118976-T1 (CY)
Title: Κρυσταλλικες τροποποιησεις της (1r,2r)-3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινολης
Inventor: GRUSS MICHAEL
IPC: C07C215/54
Filed: 2017-04-07
Abstract: Η εφεύρεση αφορά κρυσταλλικές τροποποιήσεις της (1R,2R)-3-(3-διμεθυλαμινο-1-αιθυλ-2-μεθυλ-προπυλ)-φαινόλης, φαρμακευτικές συνθέσεις που περιέχουν αυτές τις τροποποιήσεις, καθώς και τη χρήση τους.
Patent CY-1123162-T1 (CY)
Title: Ελεγχομενης αποδεσμευσης φαρμακευτικα σκευασματα νιταζοξανιδης
Inventor: ROSSIGNOL JEAN FRANCOIS
IPC: A01N43/60
Filed: 2020-07-07
Abstract: Παρέχονται στερεά δοσολογικά σκευάσματα νιταζοξανίδης, ή ενός αναλόγου νιταζοξανίδης, τα οποία περιλαμβάνουν ένα τμήμα ελεγχόμενης αποδέσμευσης και ένα τμήμα άμεσης αποδέσμευσης. Η φαρμακευτική σύνθεση έχει τυπικά τη μορφή μιας διστρωματικής στερεής από του στόματος δοσολογικής μορφής που περιλαμβάνει (α) ένα πρώτο στρώμα που περιλαμβάνει μια πρώτη ποσότητα νιταζοξανίδης, ή ενός αναλόγου αυτής, σε ένα σκεύασμα ελεγχόμενης αποδέσμευσης• και (β) ένα δεύτερο στρώμα που περιλαμβάνει μια δεύτερη ποσότητα νιταζοξανίδης, ή ενός αναλόγου αυτής, σε ένα σκεύασμα άμεσης αποδέσμευσης. Επίσης παρέχεται μια μέθοδος χρήσης των σκευασμάτων στην αντιμετώπιση της ηπατίτιδας C.
Patent CY-1124259-T1 (CY)
Title: Μεθοδος για παρασκευη βαρδεναφιλης και αλατων αυτης
Inventor: SZRAMKA ROMAN
IPC: C07D487/04
Filed: 2021-06-14
Abstract: Η μέθοδος σύνθεσης βάσης βαρδεναφίλης, σε άνυδρες συνθήκες, με χλωροσουλφονίωση 2-(2-αιθοξυ-φαινυλ)-5-μεθυλ-7-προπυλ-ιΗ-ιμιδαζο[5,1 -f][1,2,4]τριαζιν-4-όνης σε μείγμα θειονυλχλωριδίου και σουλφοχλωριδικού οξέος, που ακολουθείται από αμιδίωση του προϊόντος, χλωρίδιο 4-αιθοξυ-3-(5-μεθυλ-4-οξο-7-προπυλ-3,4-διυδροϊμιδαζο[5,1-f][Ι,2,4]τριαζιν-2- υλ)βενζολοσουλφονικού οξέος με Ν-αιθυλπιπεραζίνη, σε απρωτικό διαλύτη, παρουσία ανόργανης βάσης και η μέθοδος μετατροπής του προϊόντος, βάση βαρδεναφίλης, για απόδοση τριϋδρίτη μονοϋδροχλωρικής βαρδεναφίλης, που έχει σημείο τήξης στους 234 °C με επαφή με ύδωρ της άνυδρης τροποποίησης V μονοϋδροχλωρικής βαρδεναφίλης σε οργανικό διαλύτη. Το αντικείμενο της εφεύρεσης είναι επίσης η άνυδρη τροποποίηση V μονοϋδροχλωρικής βαρδεναφίλης και η χρήση αυτής στην παρασκευή τριϋδρίτη μονοϋδροχλωρικής βαρδεναφίλης που έχει σημείο τήξης στους 234 °C.
Patent GR-930300102-T1 (GR)
Title: Pressure cooking vessel.
Inventor: THELEN ARNOLD
IPC: A47J27/08
Filed: 1993-10-29
Abstract: The invention relates to a pressure cooking vessel having a container (1) which is intended to receive the article to be cooked and can be closed pressure-tightly with the aid of a lid (3) which can be placed on the container edge (2) and locked therewith, in which, by means of a closing mechanism provided on the lid, closure members (4) can be moved by an actuating device between a radially retracted opening position, in which the lid (3) can be removed from the container (1), into a locking position pushed radially outwards, in which the lid (3) is pressed along its circumference against a region of the container edge (2) with interposition of a circumferential sealing ring (5). The container wall (6) has on its inside in the region of the container edge (2) a locking shoulder (7), for example pointing towards the container bottom, and a sealing shoulder (9), for example pointing towards the container opening (8), and the closure members (4) are supported in a locking position pushed radially outwards on the locking shoulder (7) with compression of the sealing ring (5) against the sealing shoulder (9).
Patent GR-930300117-T1 (GR)
IPC: A47G19/02
Filed: 1993-11-30
Abstract: The tray-like carrying device for tableware consists essentially of a flat, rigid plate. A plurality of cutouts or depressions allow accommodation of a plate and, if appropriate, of a drinking glass with a stem. A gripping cutout allows the carrying device to be held and transported with one hand. 
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Patent HR-P20110130-T1 (HR)
Inventor: MCKENNA WILLIAM HENRY
IPC: A61K9/22
Filed: 2011-02-23
Abstract: Farmaceutski oblik doziranja s produljenim otpuštanjem u krutom obliku koji sadrži formulaciju matrice s produljenim otpuštanjem, formulacija matrice s produljenim otpuštanjem sadrži sastav koji sadrži barem: barem jedan polietilen oksid koji ima, prema reološkim mjerenjima, približnu molekulsku težinu od barem 1,000,000, ibarem jedan aktivni agens, ipri čemu je formulacija matrica s produljenim otpuštanjem stvrdnuta pri temperaturi od barem oko 60 °C u vremenskom periodu od oko 1 minute i ima snagu pucanja od barem oko 110 N kada je podvrgnut indentacijskom testu. Patent sadrži još 29 patentnih zahtjeva.
Patent HR-P20110870-T1 (HR)
Inventor: NEULINGER ANDREAS
IPC: H02G3/04
Filed: 2011-11-22
Abstract: Valovita cijev za kablove za električne instalacije (1) za smještaj vodova, sa izbočinama (4) u unutrašnjosti valovite cijevi (1) koja smanjuju kontaktnu površinu za vodove koji se provlače kroz valovite cijevi (1), naznačena time da su izbočine (4) izvedene kao potporne brazde (5) koje se pružaju u uzdužnom smjeru i koje su oblikovane na unutrašnjoj površini cijevi. Patent sadrži još 10 patetnih zahtjeva.
Patent SI-1187093-T1 (SI)
Title: Stand for musical instruments
Inventor: WILFER HANS-PETER
IPC: G10G5/00
Filed: 2000-08-30
Abstract: The stand for a musical instrument has a frame (13) with two longitudinal supports (14,15) which extend in parallel and define a support surface for the guitar (11). An upper support bar (18) is attached to the frame to receive the neck of the guitar (12). The upper support extends parallel to the longitudinal supports. The longitudinal supports are connected together at one end.
Patent SI-1426638-T1 (SI)
Title: Fixing device for control cables between a casing support receiving a control lever and a vehicle gearbox
Inventor: PRADIER PHILIPPE
IPC: F16H61/36
Filed: 2003-12-01
Abstract: The system for fixing control cables (C1 -C2) in a gear lever mounting comprises a sleeve (2a) with latches (2a1) attached to the mounting. A second sleeve (1) with corresponding latches (1a) attached to the cable clips on to this.
Patent SI-2817407-T1 (SI)
Title: Oligonucleotides for modulating gene expression and uses thereof
Inventor: TONELLI ROBERTO
IPC: C12N15/00
Filed: 2013-02-21
Abstract: The present invention regards oligonucleotides for modulating the expression of a gene, in particular for modulating a gene responsible for a pathology of genetic, tumoural or viral origin. Moreover, the present invention relates to the use of said oligonucleotides, possibly chemically modified, for the treatment and/or the diagnosis of said diseases.
Patent DE-3686257-T2 (DE)
Inventor: EATON ANTHONY
IPC: C12N9/02
Filed: 1986-09-19
Granted: 1993-03-04
Abstract: A process for the production of a polypeptide having a C-terminal amide group where the polypetide has one or more cysteine or cystine amino acid residues. A second polypetide comprising the amino acid sequence of the first polypeptide and a C-terminal glycine amino acid residue and where the cysteine or cystine sulphur group or groups is or are protected is reacted with an amidating enzyme capable of converting the C-terminal glycine amino acid residue to an amide.
Patent DE-3780814-T2 (DE)
Inventor: DATEMA ROELF
IPC: C07H19/09
Filed: 1987-12-16
Granted: 1992-12-10
Abstract: Use of a compound of formula (I), wherein A is  beta -2'-deoxy-D-ribofuranosyl or  beta -D-arabinofuranosyl; R<1> is hydroxy or amino; R<2> is cycloalkyl or alkyl-substituted cycloalkyl containing 1-5 carbon atoms; saturated or unsaturated, straight or branched alkyl containing 1-5 carbon atoms which may be unsubstituted or substituted with halogen, hydroxy, mercapto, trifluoroalkyl or difluoroalkyl containing 1-3 carbon atoms, phenoxy or alkoxy containing 1-3 carbon atoms; phenyl or phenylalkyl containing 1-3 carbon atoms in the alkyl part, or a physiologically acceptable salt thereof, for manufacture of a medicament for therapeutic or prophylactic control or treatment of retrovirus, especially HIV, or hepatitis B virus infections in animal and man and to a method of such treatment.
Patent DE-3784089-T2 (DE)
Inventor: ALVAREZ DELEGIDO CARLOS
IPC: F21Y103/00
Filed: 1987-04-07
Granted: 1993-08-05
Abstract: A set of assemblable components for lighting installations comprises complementary channel profiled members (2,3) with sets of ribs and grooves (4) for engagement with one another to form a box-like hollow body (1) having within it ribs or wings (6) for fastening electrical components for feeding and assembling lamps, a lid (7) being mounted at the ends of the assembled profiled members (2,3) and having outer assembly and electrical connection means (10) for engagement and means (11,12) for electrical connection with the lids (7) of adjacent box-like hollow bodies and in respect to assembly and connection bodies mounted in intermediate distribution junctions (28) located at desired points of the layout, the assembly lids (7), as well as the distribution junctions (28), having means for fastening suspension struts (23).
Patent DE-3879395-T2 (DE)
Inventor: MIKI TETSUZO
IPC: A61K38/00
Filed: 1988-05-28
Granted: 1993-06-24
Abstract: A new protein contains a polypeptide contg. a site which combines with protein-A antibody, together with a lymphotoxin polypeptide. The sequence of the protein is given (440 amino-acid residues). Also claimed are a DNA sequence coding for the protein, a plasmid (pPRALT-1) incorporating the DNA sequence; E. coli transformants contg. plasmid pPRALT-1; and the prodn. of the new protein by culture of the transformant organisms.
Patent DE-3879444-T2 (DE)
Inventor: VAN DER SCHEER DERK
IPC: H01H71/10
Filed: 1988-12-28
Granted: 1993-09-16
Abstract: An electromagnetic switch with a housing (1) provided with at least one magnet system (2), comprising a stator body (3) of magnetic material having an oblong chamber (6) accomodating a movable armature (7) of magnetic material, with an exciter winding (10) for the excitation of a magnetic field in the at least one magnet system (2). A swingably supported first arm (15) can be brought into motion under the influence of the excited magnetic field. To actuate a pair of contacts (23, 24) a swingably supported second (16) arm is provided, on each of said first and second (16) arms one end of at least one leaf spring (13, 14) acts. Said first (15) and second (16) arms extending on either side of the chamber (6) at right angles to the lengthwise direction thereof in such a way that each of them can swing about their support point (40, 42) in the direction of the armature (7). The free end (19) of the first arm (15) is coupled to the armature (7), which has an operating element (8) which acts on the second arm (16).
Patent DE-3884161-T2 (DE)
Inventor: COTTER DAVID
IPC: G02F1/35
Filed: 1988-12-09
Granted: 1994-03-10
Abstract: An optical device comprises a 50-50 cross-coupler (4) having a pair of ports (10, 12) optically coupled by a waveguide (14) which includes a portion of material (16) having a non-linear refractive index with a relaxation time such that the effect on the non-linear portion (16) of a first pulse passing through the portion last long enough to affect the phase of a second pulse relative to the first. It finds application as a logic element, optical amplifier modulator and the like.
Patent TR-199802382-T2 (TR)
Inventor: HENDRIKS HENRICUS ENGELBERTUS
IPC: C08L53/02
Filed: 1997-05-16
Abstract: Mevcut bulus, bir zift bileseni, bilesimin agirliginin %8' inden daha az  miktarda bir termoplastik lastik ve etilen-vinil asetat kopolimerin agirliginin  %20'si ile 35'i arasinda bir vinil içerigine sahip oldugu, bilesimin toplam agirliginin  %5' inden daha az miktarda bir etilen-vinil asetat kopolimer içeren bir zift bilesimi, bu tür bir zift bilesimini hazirlamak için bir islem ve yol uygulamalari için asfalt karisimlarinda bu tür zift bilesimlerinin kullanimini saglar.
Patent AT-E482730-T2 (AT)
Inventor: BOYNTON THOMAS
IPC: A61M27/00
Filed: 2002-08-23
Granted: 2010-10-15
Abstract: A system for stimulating healing of tissue at a wound site (12) is described comprising: 
a porous pad (11); 
a pump (14) for delivering a pressure and adapted to apply a variable reduced pressure to the wound site through said porous pad; and 
a controller (84) regulating the pump to vary the pressure by comparing the pressure to a variable target pressure and changing the pressure in predefined pressure intervals between a first reduced pressure and a second reduced pressure in response to the comparison.
Patent DE-60002595-T2 (DE)
Inventor: LONARDI EMILE
IPC: C21B7/20
Filed: 2000-08-16
Granted: 2004-03-18
Abstract: A device for distributing materials in bulk includes a suspension rotor and a chute located below the suspension rotor. The chute is provided with two lateral suspension arms which are connected to the suspension rotor. A driving mechanism produces a pivoting torque capable of pivoting the chute, while a cylindrical suspension pin is associated with each suspension arm for pivotably connecting it to the suspension rotor. A control lever is connected to the suspension rotor, the driving mechanism being connected to the control lever so as to transmit to the latter the pivoting torque. A stop on the control lever and a counterstop on a suspension arm engage with each other to transmit the pivoting torque to the suspension arm. The stop and the counterstop are disengagable by a translation movement of the two suspension arms after withdrawal of the cylindrical suspension pins for removal of the chute.
Patent DE-60005966-T2 (DE)
Inventor: GRASSWILL VINCENT
IPC: B65H29/12
Filed: 2000-06-07
Granted: 2004-09-02
Abstract: The device for the high-speed conveying of post envelopes (2A, 2B) comprises a fixed sole plate (11) extending along the path which the conveyed envelopes follow and along which the envelopes, standing on edge and arranged in series, glide, a motorized endless reference belt (12) stretched along one side of the sole plate, a motorized endless press belt (14) stretched along the other side of the sole plate, and a series of elastically deformable elastomer wheels (16) for elastically pressing against the reference belt in such a way as to grip the envelopes arranged on the sole plate between the reference belt and the press belt. The wheels (16) each have a hub mounted to rotate on a stationary spindle, and an annular tread strip in contact with the press belt, the hub and the annular tread strip of each wheel being connected by elastically deformable circular-arc-shaped fins. The two ends of each fin, which are for connection to the hub and to the annular tread strip of the wheel, lie on a radius of the wheel.
Patent DE-60008441-T2 (DE)
Inventor: BARAVALLE UGO
IPC: B60R9/045
Filed: 2000-01-19
Granted: 2004-12-23
Abstract: The fixing foot comprises a body (14) fixed to one end of a load-carrying cross-member (10) and shaped for bearing on a longitudinal rail (R) of a motor-vehicle roof. The body (14) contains a nut-and-bolt tensioning device (30) of which the bolt (32) has a head (36) which can be operated from above. The two ends (44) of a substantially inextensible loop (42) are anchored to a slide (38) incorporating a nut (40). The loop (42) is passed under the rail (R) and is hooked onto an engagement member (54) fixed to the slide (38). Rotation of the bolt (32) in one direction tensions the loop (42) by raising both the ends (44) of the loop which are anchored to the slide (38), and the tip (46) of the loop which is hooked onto the engagement member (54). The loop (42) is thus put under tension, fastening the rail (R) between the body (14) and the loop. <IMAGE>
Patent DE-60010719-T2 (DE)
Inventor: CUPERTINO DOMENICO CARLO
IPC: C22B15/00
Filed: 2000-05-30
Granted: 2005-05-12
Abstract: A solvent extraction composition is provided which comprises one or more orthohydroxyarylaldoxime or orthohydroxyarylketoxime and at least one dialkyl ester of an optionally substituted ethylene or polyethylene glycol and preferably a water immiscible organic solvent. The orthohydroxyarylaldoximes, or orthohydroxyarylketoximes commonly are of Formula (1),wherein R<1 >is hydrogen or a hydrocarbyl group, and R<2 >is an ortho-hydroxyaryl group; and the dialkyl esters of an optionally substituted ethylene or polyethylene glycol commonly are of Formula (2),wherein R<7 >and R<8 >are each independently an optionally substituted alkyl group; R<9 >to R<20 >are each independently hydrogen or optionally substituted hydrocarbyl; m, n and p are each independently 0, 1, 2, 3 or 4 provided that m+n+p is greater than or equal to 1; and q is 1, 2 or 3. Preferred orthohydroxyarylaldoximes are 5-(C9 to C14alkyl)-2-hydroxybenzaldoximes and preferred orthohydroxyarylketoximes are 5-(C9 to C14alkyl)-2-hydroxyacetophenone oximes. Preferred dialkyl esters of an optionally substituted ethylene or polyethylene glycol are branched dialkyl esters comprising from 10 to 100 carbon atoms, wherein R<7 >or R<8 >are branched alkyl groups. Processes for the extraction of metal values from aqueous acidic and ammoniacal solutions are also provided.
Patent DE-60013823-T2 (DE)
Inventor: BUTLER WILLIAM
IPC: A61M25/00
Filed: 2000-05-10
Granted: 2005-11-17
Abstract: A splittable occlusion balloon sheath includes a splittable sheath onto which an occlusion balloon has been secured near the distal end of the splittable sheath. A splittable hemostasis valve or a partitioned hemostasis valve system may also be secured within or to the splittable occlusion balloon sheath. This splittable occlusion balloon sheath is utilized to introduce a medical device, such as electrode leads, into the coronary sinus of the human heart. A dilator may also be used with the splittable occlusion balloon sheath for introduction of the medical devices. The splittable occlusion balloon sheath and/or the dilator may be precurved with a particular shape to assist in the introduction of the splittable occlusion balloon sheath and/or dilator into the coronary sinus. Also disclosed is a process of use of the splittable occlusion balloon system within the coronary sinus.
Patent DE-60016384-T2 (DE)
Inventor: KITAMURA HIDETOMO
IPC: A61K31/443
Filed: 2000-01-26
Granted: 2005-12-01
Abstract: A chondrogenesis promoter comprising as an active ingredient a compound represented by general formula (I) or a salt thereof: <CHEM> wherein R<1> represents a halogen atom, a lower alkyl group, a lower alkoxy group, etc.; R<2> represents a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a lower alkoxy group, an acyl group, an aryl group, a heterocyclic group, etc.; R<3> represents a lower alkyl group, a cycloalkyl group, an aryl group, a heterocyclic group, etc.; R<4> represents a hydrogen atom, a lower alkyl group, an aryl group, a heterocyclic group, etc.; X and Y represent -CH2-, -NH- or -O-; and n represents an integer of 0-4.
Patent DE-60017115-T2 (DE)
Inventor: USHIO HIROYUKI
IPC: C07D491/10
Filed: 2000-02-10
Granted: 2005-12-08
Abstract: The present invention relates to a compound of the formula <CHEM> wherein R<1> is substituted aryl, heteroaryl and the like, R<2> and R<3> are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X' is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.
Patent DE-60017565-T2 (DE)
Inventor: DELEAM DAVID
IPC: H04L12/64
Filed: 2000-06-22
Granted: 2006-02-23
Abstract: The invention concerns a method for decoding and retrieving a sound signal in an asynchronous transmission system which consists in detecting an backfilling overload in said buffer memory and/or a second memory in the input or the output of the decoding unit and comparing the backfilling rate to at least a threshold. The invention is characterised in that, depending on the value of the backfilling rate, it consists in using a detection of voice activity and in eliminating the frames considered as being non-active by said detection; carrying out a concatenation processing on two successive frames.