baber/WOPTO huggingface dataset:
Patent WO-2019051558-A1 (WO)
Title: Inhibition of c. difficile sporulation
Inventor: LYRAS DENA
IPC: A61P31/04
Filed: 2018-09-14
Abstract: This invention relates to methods of inhibiting and reducing C. difficile sporulation, and in turn, by virtue of having inhibited or reduced sporulation, treating C. difficile infection, reducing the symptoms of C. difficile infection, reducing the risk of transmission of C. difficile and reducing the risk of reinfection. The methods involve the administration of a cephamycin, and optionally with an antibiotic that inhibits vegetative C. difficile cells. The invention also relates to a pharmaceutical composition comprising a cephamycin and an antibiotic that inhibits vegetative C. difficile cells, and the use of that composition for the above mentioned purposes.
Patent AU-2018200721-A1 (AU)
Title: Compositions and methods of inhibiting MASP-1, MASP-2 and/or MASP-3 for treatment of paroxysmal nocturnal hemoglobinuria
Inventor: SCHWAEBLE HANS WILHELM
IPC: C07K16/46
Filed: 2018-01-31
Abstract: In one aspect, the invention provides methods and compositions for inhibiting MASP-3-dependent complement activation in a subject suffering from paroxysmal nocturnal hemoglobinuria by administering to the subject a composition comprising an amount of a MASP-3 inhibitory agent in an amount effective to inhibit MASP-3 dependent complement activation. In another aspect, the invention provides methods and compositions for increasing the survival of red blood cells in a subject suffering from paroxysmal nocturnal hemoglobinuria by administering to the subject a composition comprising an amount of at least one of a MASP-1 inhibitory agent and/or a MASP-3 inhibitory agent effective to increase the survival of red blood cells. In some embodiments, the subject is administered a MASP-2 inhibitory agent and a MASP-1 inhibitory agent, a MASP-2 inhibitory agent and a MASP-3 inhibitory agent administered, a MASP-3 inhibitory agent and a MASP-1 inhibitory agent, or a MASP-1 inhibitory agent, a MASP-2 inhibitory agent and a MASP-3 inhibitory agent.
Patent AU-2018200854-A1 (AU)
Title: A method for managing electrical energy in a railway vehicle, corresponding power management system, and corresponding railway vehicle
Inventor: VIENNE MATHIEU
IPC: B60L3/12
Filed: 2018-02-06
Abstract: A method for managing electrical energy for several pieces of energy-consuming equipment (20) in a railway vehicle (1) from on board energy storage (10), in particular when the railway vehicle (1) is crossing a geographical zone without a power grid, the method comprising the following steps. - obtaining at least one energy parameter representative of an available energy level in the energy storage, - for each piece of consuming equipment, determining a desired operating state, taken from among a plurality of operating states corresponding to different electricity consumption levels, the determination using at least the energy parameter and optionally the localization parameter, and - sending each piece of consuming equipment an operating setpoint depending on the desired operating state. Corresponding energy management system and railway vehicle. Figure 1 00 to rj 00 ~ to p -- -- - -- -L - -- - -- - -- i-- -------- -j --2 --- - __ I I _C___ Lto U--
Patent AU-2018204320-A1 (AU)
Title: Systems and methods for assessing the insurance risk of driver behavior using gps tracking and machine learning
Inventor: KILBURN CHRISTOPHER BJORN
IPC: G06Q10/08
Filed: 2018-06-15
Abstract: Methods, devices, and systems for tracking an asset are provided. In particular, a device is provided that includes a processor; a wide-area network radio; an accelerometer; a physical interface; and a computer-readable storage medium storing computer-readable instructions. The processor captures first data from the accelerometer. The processor captures second data from 0 one or more sensors via the physical interface. The processor captures location data. The processor sends the first data, the second data, and the location data to a network location. The processor receives an overall risk level based on the first data, the second data, the location data, and external data. The processor determines the overall risk level exceeds a threshold. The processor records event occurrence data in a database. cc 00(. CN m7
Patent AU-2018226510-A1 (AU)
Title: Manual release systems for ambulance cots
Inventor: VALENTINO NICHOLAS V
IPC: A61G7/012
Filed: 2018-09-07
Abstract: Embodiments of a cot comprise a support frame, legs coupled to the support frame, at least one hydraulic actuator configured to raise or lower the legs, and a manual release system coupled to the at least one actuator and configured to lower the cot manually at a controlled descent rate. The manual release system comprises a manual actuation component, a manual release valve operable to be opened upon actuation by the manual actuation component, a fluid reservoir operable to receive hydraulic fluid from the at least one actuator upon opening of the manual valve; and a flow regulator configured to control the flow rate of the hydraulic fluid into the fluid reservoir, wherein the release of hydraulic fluid into the fluid reservoir at the controlled flow rate is configured to manually lower the cot at the controlled descent rate. 10627253_1 (GHMaters) P100126.AU.1 WO 2014/089180 PCT/US2013/073069 356-_ cm361 =
Patent AU-2018227413-A1 (AU)
Title: Split reservoir bags and method of using split reservoir bags to improve the heating and generation of dialysate
Inventor: GRODER SETH HOWARD
IPC: A61J1/10
Filed: 2018-02-26
Abstract: The present specification provides a reservoir bag for containing a dialysate during a dialysis treatment. The bag has four walls and a membrane extending from a first wall to a second opposing wall which divides the bag into a first and a second sub-reservoir having changeable volumes. The maximum volume of each sub-reservoir is between 80 to 100% of the entire volume of the bag. The bag further includes at least an inlet and an outlet positioned in at least one of the walls for enabling fluid entry into and exit out of the first sub-reservoir and at least an inlet and an outlet positioned in at least one of the walls for enabling fluid entry into and exit out of the second sub -reservoir.
Patent AU-2018254468-A1 (AU)
Title: P-ethoxy nucleic acids for BCL2 inhibition
Inventor: ASHIZAWA ANA TARI
IPC: C07H21/02
Filed: 2018-04-19
Abstract: Provided herein are improved delivery systems for oligonucleotides, said delivery system comprising a liposome that comprises neutral phospholipids and a P-ethoxy oligonucleotide, which targets a BCL2-encoding polynucleotide. Methods of treating patients with said delivery systems are also provided.
Patent AU-2018256602-A1 (AU)
Title: Functionalized benzamide derivatives as antiviral agents against hbv infection
Inventor: BLOCK TIMOTHY M
IPC: A61M31/00
Filed: 2018-11-01
Abstract: Novel functionalized benzamide derivatives are provided. Also provided are pharmaceutical compositions comprising therapeutically effective amounts of functionalized benzamide derivatives useful as pregenomic RNA encapsidation inhibitors, useful for the treatment of Hepatitis B virus (HBV) infection, in combination with at least one pharmaceutically acceptable excipient. Functionalized benzamide derivatives of the invention include N-aryl substituted 1-naphthamide and 2-naphthamide derivatives.
Patent AU-2018256631-A1 (AU)
Title: Blood sample management using open cell foam
Inventor: IVOSEVIC MILAN
IPC: A61B10/00
Filed: 2018-11-02
Abstract: A specimen transfer device adapted to receive a blood sample is disclosed. The specimen transfer device includes a housing and an actuation member. A deformable material is disposed within the housing and is deformable from an initial position in which the material is adapted to hold the sample to a deformed position in which at least a portion of the sample is released from the material. A viscoelastic member is disposed within the housing between the material and the housing and between the material and the actuation member. The viscoelastic member is engaged with the actuation member and the material such that movement of the actuation member from a first position to a second position deforms the material from the initial position to the deformed position. N Co re.). C; -
Patent AU-2018258947-A1 (AU)
Title: Process for the manufacture of vortioxetine HBr alpha-form
Inventor: PETERSEN HANS
IPC: C07D295/06
Filed: 2018-04-20
Abstract: A process for the manufacture of vortioxetine HBr α-form is provided.
Patent AU-2018276805-A1 (AU)
Title: Method and system for handling a catch of fish in a fishing vessel
Inventor: LARSEN ASBJØRN INGEMAR
IPC: B63B35/14
Filed: 2018-05-31
Abstract: This publication relates to a system and a method for hauling fish gear, such as longlines, gillnets or demersal seine nets, into a fishing vessel (10) and collecting and transporting catch (12) to a working station, using a hatch (16) in a part of a hull exposed to the sea and arranged in a water line region (27) of the vessel (10); a vertical well (18) for receipt of at least a part of the catch through the hatch (16); a transport device for transporting the catch to the deck; and with means for bringing the catch to flow towards the transport device. The transport device (24,25) used is arranged in a shaft (19), separated from the well (18), and a closable opening or hatch (23) is arranged in a wall or bulkhead (21) between the well (18) and the shaft (19) and with a devices for opening and closing the opening or hatch (23), a bottom (22) in the shaft (19) arranged at a lower level than the lower end of the closable opening or hatch (23) and a water level in the well (18); and a device for reducing the water level in the shaft (19).
Patent AU-2018305876-A1 (AU)
Title: Method for the preparation of synthesis gas
Inventor: AASBERG-PETERSEN KIM
IPC: C01B13/02
Filed: 2018-07-20
Abstract: Method for the preparation of synthesis gas based on a combination of the ATR process or partial oxidation of hydrocarbon fee stock using oxygen from the electrolysis of water and an air separation unit to produce the synthesis gas.
Patent AU-2018307969-A1 (AU)
Title: Directional balloon transseptal insertion device for medical procedures
Inventor: MAINI BRIJESHWAR S
IPC: A61B18/14
Filed: 2018-07-27
Abstract: A transseptal insertion device suitable for facilitating precise and safe transseptal puncture of a cardiac interatrial septum includes a sheath (12) that defines a lumen and has a distal end that is closest to the cardiac interatrial septum of a patient and a proximal end that is external to the patent, a balloon (14) that is connected to the distal end of the sheath (12), in which the balloon (14), when inflated, overhangs and extends past the distal end of the sheath (12), preventing accidental puncturing of the cardiac interatrial septum and stabilizing the transseptal insertion device against fossa ovalis of the cardiac interatrial septum, and a dilator (16) that is positioned within the at least one lumen. The dilator (16) has a distal end and is designed to and is capable of precisely puncturing the cardiac interatrial septum without the use of a needle or other sharp instrument.
Patent AU-2018316734-A1 (AU)
Title: HPV vaccine
Inventor: DORRELL LUCY
IPC: A61K39/12
Filed: 2018-08-16
Abstract: The invention relates to a nucleic acid encoding a polypeptide comprising a plurality of conserved peptide sequences, or variants thereof, wherein the conserved sequences are conserved across one or more HPV genotypes 16, 18, 31, 52, 53, and 58; and wherein the polypeptide comprises a conserved peptide sequence of each of the HPV proteins E1, E2, E4, E5, E6, and E7; and associated vaccines, viral vectors, treatment and prophylaxis.
Patent AU-2018319544-A1 (AU)
Title: Dose detection module for a medication delivery device
Inventor: ANTONELLI MATTHEW THOMAS
IPC: A61M5/315
Filed: 2018-02-22
Abstract: The present disclosure relates to a dose detection system for use with a medication delivery device in which a dose setting member rotates relative to an actuator during dose delivery. The dose detection system includes a module which is removably attached to the medication delivery device. The module includes a rotation sensor attached to the actuator during dose delivery. A sensed element is attached to the dose setting member and includes surface features detectable by the rotation sensor. The rotation sensor comprises a following member including a contact portion resting against and spring-biased in the direction of the surface features. The contact surface is positioned to move over the surface features during rotation of the sensed element, and the rotation sensor is responsive to the movement of the contact portion over the surface features to detect the rotation of the dose setting member.
Patent AU-2018371846-A1 (AU)
Title: Improved maxillary expander and protraction device
Inventor: KAVEH CAMERON
IPC: A61C7/06
Filed: 2018-11-24
Abstract: A medical device and method of expanding the maxilla of a patient via application of intra-orally generated forces and/or applying externally generated protraction forces to the maxilla of the patient is provided. The medical device can embody multiple configurations device that include skeletal anchorage device alone or in combination with a fixed aligner or an adjustable aligner.
Patent AU-2018403071-A1 (AU)
Title: Sidewall with buckstay for a metallurgical furnace
Inventor: FERGUSON SCOTT A
IPC: F27B1/12
Filed: 2018-05-10
Abstract: A sidewall for a metallurgical furnace and a metallurgical furnace having the same are described herein. In one example, a sidewall of a metallurgical furnace is provided that includes an outer wall, a hot plate and a buckstay. The hot plate is coupled in a spaced apart relation to the outer wall. The buckstay is mechanically coupled to the outer wall and the hot plate. The buckstay includes a buckstay web extending from a buckstay flange. The buckstay web includes a first end coupled to the buckstay flange, and a second end mechanically and movably coupled to the hot plate.
Patent AU-2018424859-A1 (AU)
Title: A cardiac valve prosthesis
Inventor: CARLINO FELICE GIUSEPPE
IPC: A61F2/24
Filed: 2018-05-23
Abstract: A cardiac valve prosthesis including an armature for anchorage of the valve prosthesis at an implantation site. The armature defining a lumen for the passage of the blood flow and having a longitudinal axis, and a set of prosthetic valve leaflets supported by said armature and configured to move, under the action of blood flow, in a radially divaricated condition to enable the flow of blood through said lumen in a first direction, and in a radially contracted condition, in which said valve leaflets co-operate with one another and block the flow of blood through the prosthesis in the direction opposite said first direction. The armature including an annular part and a pattern of arched struts carried by said annular part, said pattern of arched struts having proximal ends connected to said annular part, and distal ends spaced axially from the proximal ends and opposite said annular part, a plurality of sets of anchoring formations configured to protrude radially outwardly of said annular part, each set being supported by at least one of said annular part and a corresponding arched strut, and a plurality of support posts, each support post being supported by adjacent arched struts, wherein the sets of anchoring formations alternate with the support posts around said longitudinal axis.
Patent AU-2018445887-A1 (AU)
Title: Pet food compositions
Inventor: BADRI DAYAKAR
IPC: A23K20/158
Filed: 2018-10-18
Abstract: Described herein are pet food compositions for enhancing nicotinamide adenine dinucleotide metabolism and increasing levels of nicotinamide adenine dinucleotide oxidized form, the food composition including a protein, a carbohydrate, and a dietary fiber that includes insoluble fiber and soluble fiber in a weight ratio ranging from about 8:1 to about 14:1, whereby the dietary fiber is present in an amount ranging from about 2 wt. % to about 10 wt. % based on the total weight of the food composition.
Patent WO-2019173867-A1 (WO)
Title: Visualising clinical and disease data
Inventor: GROZA TUDOR
IPC: G16H50/70
Filed: 2019-03-12
Abstract: This disclosure relates to generating interactive graphical visualisations of clinical and data. A processor calculates a phenotype-to-phenotype similarity value indicative of a similarity between observed phenotypes and each phenotype in a set of stored phenotypes based on an ontology of phenotypes. The processor then determines an assignment of stored phenotypes to observed phenotypes based on the similarity values and further aggregates the similarity values into a set-to-set similarity value indicative of a similarity between the observed phenotypes and the set of stored phenotypes. The processor then repeats these steps to calculate a set-to-set similarity measure for each of the multiple sets. Finally, the processor selects one or more of the multiple sets based on the set-to-set similarity value and generates a graphical user interface comprising a graphical indication of the selected one or more of the multiple sets in relation to the multiple observed phenotypes.
Patent AU-2019200628-A1 (AU)
Title: Network-based microbial compositions and methods
Inventor: HENN MATTHEW R
IPC: A01N63/00
Filed: 2019-01-31
Abstract: Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof.
Patent AU-2019201722-A1 (AU)
Title: Microfluidic drug delivery devices
Inventor: ANAND P J
IPC: A61M25/14
Filed: 2019-03-13
Abstract: The methods, systems, and devices disclosed herein generally involve convection enhanced delivery of drugs to a target region within a patient. Microfluidic catheter devices are disclosed that are particularly suitable for targeted delivery of drugs via convection, including devices capable of multi-directional drug delivery, devices that control fluid pressure and velocity using the venturi effect, and devices that include conformable balloons. Methods of treating various diseases using such devices are also disclosed, including methods of treating cerebral and spinal cavernous malformations, cavernomas, and hemangiomas, methods of treating neurological diseases, methods of treatment using multiple microfluidic delivery devices, methods of treating hearing disorders, methods of spinal drug delivery using microfluidic devices, and methods of delivering stem cells and therapeutics during fetal surgery. Methods of manufacturing such devices are also disclosed.
Patent AU-2019204150-A1 (AU)
Title: Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
Inventor: BUTLER DAVID
IPC: C12N15/87
Filed: 2019-06-13
Abstract: Abstract The invention relates to compositions and methods for site-specific delivery of nucleic acids by combining them 5 with targeting ligands and endosomolytic components.
Patent AU-2019204824-A1 (AU)
Title: System and method for tensioning a conveyor in a mining system
Inventor: NEIL JR PAUL A
IPC: B65G23/44
Filed: 2019-07-04
Abstract: A tensioning system for a conveyor element of a conveyor is provided. The tensioning system includes an obstruction. A base is movable relative to the obstruction. The tensioning system further includes a plurality of spacers. At least one spacer of the plurality of spacers is movable from a resting position to an engagement position by only the influence of gravity. The at least one spacer rests on the obstruction in the resting position. The at least one spacer is disposed between the base and the obstruction in the engagement position. 11501386 1 (GHMatters) P111579.AU 10 O C:) C(0 (00 C) C'CN (04
Patent AU-2019208176-A1 (AU)
Title: Antibacterial therapeutics and prophylactics
Inventor: SENGUPTA SHILADITYA
IPC: C07D513/04
Filed: 2019-07-23
Abstract: The present disclosure relates generally to novel molecules, compositions, and formulations for treatment of bacterial infections in general and more specifically to bacterial infections with antibiotic resistant pathogens. 11546471_1 (GHMatters) P10800O.AU.1
Patent AU-2019222960-A1 (AU)
Title: Link error correction in memory system
Inventor: SUH JUNGWON
IPC: G06F11/10
Filed: 2019-08-30
Abstract: Methods and apparatus for link error correction in a memory system are disclosed. In one embodiment a method comprises sending, by a host, a WRITE command to a memory device over a link; generating, by the host, a write protection code based on Write Data, the write protection code being a code for protection of the Write Data; sending, by the host, the Write Data and the write protection code to the memory device over the link; detecting, by the memory device, whether the Write Data has an error based on the write protection code; and storing, by the memory device, the Write Data to a memory bank of the memory device in response to the WRITE command, wherein the link comprises a plurality of data (DQ) lines, a data mask (DM) line for use in by the host in mask write operations, and a Read Strobe clock line for use by the memory device to provide timing in read operations, and wherein sending the Write Data and the write protection code comprises: sending, by the host, the Write Data to the memory device over the plurality of DQ lines during a write operation, and sending, by the host, the write protection code to the memory device over the Read Strobe clock line during the write operation.
Patent AU-2019230461-A1 (AU)
Title: Response monitoring
Inventor: QIAN PIERRE
IPC: A61B18/14
Filed: 2019-03-08
Abstract: The invention concerns a method for intra-operative monitoring of the effectiveness of transcatheter renal denervation in a patient, to assist in guiding the procedure and in particular for identifying a physiological procedural endpoint. Through aorticorenal ganglia pace-capture, renal sympathetic nerve function can be assessed. In accordance with the invention, sustained reduction or abolition of renal vasoconstriction induced by the pacing is used as an indicator of successful renal denervation.
Patent AU-2019233294-A1 (AU)
Title: A flexible double lumen tube and a tube coupling system for same
Inventor: BJERREGAARD HENRIK BORK
IPC: F16L39/02
Filed: 2019-03-06
Abstract: A tube coupling system serves for providing annular flow through a flexible annular double lumen tube (3) between fluid reservoir(s) and flexible connection pieces (56,57) of an annular double lumen device (2). The tube coupling system has a first coupling component (4) and a second coupling component (6) and an end fitting system. The first coupling component (4) that has a female coupling part (11) and a male coupling part (12) adapted for coupling to a proximal end (5) of the flexible annular double lumen tube (3). The second coupling component (4) has a second interior pipe (31) that axially extends inside a second exterior pipe (32), a first end fitting (33) adapted for coupling to at least the female coupling part (11) of the first coupling component (4), and a second end fitting (34) adapted for coupling to any of the flexible annular double lumen tube (3) or the flexible connection pieces (56,57) of an annular double lumen device (2).
Patent AU-2019240767-A1 (AU)
Title: Patient interface
Inventor: EVES MATTHEW
IPC: A61M16/06
Filed: 2019-03-28
Abstract: Patient interfaces having an oral portion and a nasal portion and additional features of a seal-forming structure and a shell are described. Various embodiments of a seal-forming structure are contemplated that comprise arrangements having areas with a higher resistance to deformation at laterally spaced portions of either the nasal portion or of the oral portion. Another seal forming structure comprises a bridge portion that can be deformed to accommodate different patient nose lengths. Yet another seal-forming structure comprises different surface finishes on the nasal portion and the oral portion.