baber/WOPTO huggingface dataset:
Patent CA-2621789-A1 (CA)
Inventor: WITTIG BURGHARDT
IPC: G01N33/50
Filed: 2006-09-08
Abstract: The invention relates to a method for the in vitro monitoring of the effect of substances in in vivo processes and to an in vitro detection method, for identifying immunomodulating compounds and/or for detecting the effect of immunomodulating compounds as well as for identifying compounds which induce apoptosis and/or necrosis by means of the immune system in in vivo processes.  The claimed methods are particularly suitable for monitoring the effects of substances on cells which are mediated by the immune system. Since cells of the immune system with the substances in the primary incubation can impart their effect thereon, the in vivo effects of the substances are monitored in the secondary incubation by incubating with target cells the supernatants or the mixture of cells and supernatant of the primary incubation, which contain, inter alia, the deposited products from the cells of the immune system. The claimed method is also suitable for the in vitro monitoring of the in vivo effects before, during and/or after the dosage of immunomodulating compounds as well as compounds that induce apoptosis and/or necrosis.
Patent CA-2624721-A1 (CA)
Inventor: ARNOT ROGER
IPC: F15B21/042
Filed: 2007-05-24
Abstract: A submersible heat-exchanging apparatus comprises a cylindrical heat-exchange component configured with one end for sealingly engaging a terminal plug and the other end for sealingly engaging and communicating with a coupling manifold having opposed inflow and outflow ports. A flow-directing elongate insert is provided with one end configured to engage the coupling manifold interposed the inflow and outflow ports, and the other end provided with an aperture and configured for abutting the terminal plug. The flow-directing elongate insert is configured to slidingly contact and cooperate with the inner walls of the heat-conductive conduit thereby partitioning the heat-conductive conduit into two opposed fluid transmission channels wherein one channel communicates with the inlet port and the other channel communicates with the outlet port. The coupling manifold is configured to sealingly engage an aperature provided therefore in a fluid-containing receptacle whereby the heat-exchange component extends into the receptacle.
Patent CA-2624936-A1 (CA)
Inventor: SABOLINSKI MICHAEL L
IPC: C12Q1/68
Filed: 2006-10-04
Abstract: The invention provides methods for (a) reducing mortality associated with heart failure; (b) improving oxygen consumption; (c) treating heart failure;  (d) treating hypertension; (e) improving the quality of life in a heart failure patient; (f) inhibiting left ventricular remodeling; (g) reducing hospitalizations related to heart failure; (h) improving exercise tolerance;  (j) increasing left ventricular ejection fraction; (Ic) decreasing levels of B-type natriuretic protein; (1) treating renovascular diseases; (m) treating end-stage renal diseases; (n) reducing cardiomegaly; (o) treating diseases resulting from oxidative stress; (p) treating endothelial dysfunctions; (q) treating diseases caused by endothelial dysfunctions; or (r) treating cardiovascular diseases; in a patient in need thereof, wherein the patient has a -344 (T/T) polymorphism or a -344 (C/C) polymorphism in an aldosterone synthase CYPl1B2 gene, comprising administering to the patient (i) at least one antioxidant compound or a pharmaceutically acceptable salt thereof; (ii) at least one nitric oxide enhancing compound; and (iii) optionally the best current therapy for the treatment of cardiovascular diseases. In one embodiment the antioxidant is a hydralazine compound or a pharmaceutically acceptable salt thereof and the nitric oxide enhancing compound is isosorbide dinitrate and/or isosorbide mononitrate.
Patent CA-2626229-A1 (CA)
Inventor: WOETZER PHILIPP
IPC: G01K11/00
Filed: 2006-10-16
Abstract: The invention relates to a display device (1) for refrigerated products (2), in particular for foodstuffs that are involved in a cold chain. The device comprises a reactive liquid (4) that is held in a liquid-tight manner in a container (3) and an absorbent display element (5). According to the invention, the container (3) can be destroyed by a volumetric change in the reactive liquid (4) if an adjustable temperature threshold has not been attained and the appearance of the display element (5) can be irreversibly modified by means of the liquefied reactive liquid (4). A delay device (6) is configured or placed between the container (3) and the display element (5), said device being used to variably adjust the time period between the liquefaction of the reactive liquid (4) as a result of an increase in temperature and the modification of the appearance of the display element (5) as a result of the contact with the liquefied reactive liquid (4).
Patent CA-2626475-A1 (CA)
Inventor: PROCTER MARTIN JAMES
IPC: A61K31/425
Filed: 2006-11-03
Abstract: Compounds of Formula (I) or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.
Patent CA-2628233-A1 (CA)
Title: 5-lipoxygenase-activating protein (flap) inhibitors
Inventor: HUTCHINSON JOHN H
IPC: A61K31/501
Filed: 2006-11-03
Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
Patent CA-2628453-A1 (CA)
Title: Procede de formation d'article comprenant, une pellicule durcie tiree d'une composition d'enduction de bandes en continu
Inventor: DARASKEVICH EDWARD
IPC: B05D7/14
Filed: 2007-10-25
Abstract: La présente invention concerne un procédé permettant de former un article comprenant un substrat et, sur ce dernier, un film durci constitué d'une composition d'enduction de bandes en continu. Ladite composition d'enduction de bandes en continu contient un précurseur et un agent de matité contenant un polymère à base d'amide. Le procédé selon l'invention consiste : à appliquer la composition d'enduction de bandes en continu sur le substrat; à la durcir afin de former un film durci doté d'une première région présentant une première épaisseur et un premier brillant; et à déformer le substrat afin de doter le film durci d'une seconde région du film durci possédant une seconde épaisseur, inférieure à la première épaisseur, et d'un second brillant. L'invention concerne également un système d'induction de bandes en continu comprenant le substrat et le film durci disposé sur ledit substrat. L'agent de matité stabilise le brillant du film durci, ce qui réduit au minimum la différence entre le premier brillant et le second brillant du film durci sur un substrat déformé.
Patent CA-2629622-A1 (CA)
Title: Utilisation de dispersants pour concentrer des matieres minerales dans l'eau, dispersions obtenues et leurs utilisations
Inventor: SUAU JEAN-MARC
IPC: C09K23/52
Filed: 2006-12-13
Abstract: L~invention consiste en l~utilisation d~agents dispersants, dans un procédé de fabrication d~une dispersion aqueuse de matières minérales, par : a) broyage à faible extrait sec (<= 40 %) desdites matières minérales dans l~eau sans agent dispersant et/ou d~aide au broyage, b) concentration à haut extrait sec (>= 65 %) par des moyens mécaniques et/ou thermiques, caractérisée en ce que : - au moins un agent dispersant est introduit entre l~étape a) et l~étape b), et/ou pendant l~étape b), et / ou pendant et après l~étape b), - sous la forme d~une combinaisaon : - d~au moins un homopolymère de l~acide acrylique, - et d~au moins un composé minéral fluoré.
Patent CA-2631963-A1 (CA)
Inventor: FRANCESCON OTTAVIANO
IPC: B25C7/00
Filed: 2007-01-04
Abstract: An adjustable adapter configured to position a fastening tool for driving a fastener into tongue-and-groove flooring material in order to secure the flooring material to a subfioor is disclosed. The adapter comprises a fastening tool mounting plate, a base slidably mounted to the bottom of the mounting plate and a support plate slidably mounted to the top of the mounting plate. A nose plate of the fastening tool is secured to the mounting plate between the mounting plate and the support plate and a safety actuator arm is disposed between the mounting plate and the nose plate. The base and the support plate arc movable such that the adapter can be configured to engage the tongue and the top surface of various sizes and configurations of tongue-and-groove flooring materials in order to maintain a desired fastener driving angle and insertion location.
Patent CA-2632077-A1 (CA)
Title: Hearing assistance device capacitive switch
Inventor: HIGGINS SIDNEY A
IPC: H05K9/00
Filed: 2008-05-23
Abstract: Disclosed herein, among other things, is a hearing assistance device apparatus with a capacitive switch. According to various embodiments, the apparatus includes a BTE housing, hearing assistance electronics housed in the housing and a capacitive switch connected to the hearing assistance electronics and adapted to detect a wearer when the BTE housing is worn..
Patent CA-2632314-A1 (CA)
Title: Method and apparatus for separating submerged particles from a fluid
Inventor: BRATTESTED KNUT
IPC: B01D17/02
Filed: 2006-12-07
Abstract: Present invention relates to a method and apparatus for separating particles from a fluid; particles are dispersed in the fluid and consist of lighter particles with lower density than the bulk, and heavier particles with a density higher than the bulk, method comprises the following steps: feeding the particle containing fluid to a separation device, evenly distribute the fluid over at least parts of the cross-sectional area by flowing through a distribution device (12) in an inlet chamber (11) providing the particle containing fluid with a specific velocity and leading the fluid to one ore more collecting surfaces (5, 9) coalesce the lighter particles on the collecting surface (5, 9) remove the coalesced lighter particles from the collecting surface (5, 9) remove the particle depleted fluid and the lighter coalesced particles in at least two separate streams (2, 3) optionally remove the heavier particles from the bottom of the separation device in at least one separate stream (4).
Patent CA-2634215-A1 (CA)
Title: Filter cartridge for jugs
Inventor: MORETTO MAURIZIO
IPC: C02F1/00
Filed: 2006-12-04
Abstract: A filter cartridge (10) for jugs (1), comprising: - a first chamber (13) in which there is provided filtering material (12) which is able to filter water or liquids in general and in which there are defined an inlet (14) and an outlet (15) in order to allow the passage of water through the first chamber (13) in contact with the filtering material, - a second chamber (16) which communicates with the first chamber in order to collect the water being discharged from the first chamber, in which there is defined an opening (19) for discharging the water from the cartridge, which is open in the second chamber (16) at a level that is higher than a base (17) of the second chamber (16), in which the water being discharged from the first chamber (13) is collected.
Patent CA-2634299-A1 (CA)
Title: Process for preparing inhibitors of nucleoside metabolism
Inventor: FURNEAUX RICHARD HUBERT
IPC: C07D491/056
Filed: 2000-04-07
Abstract: The invention provides a compound of the formula:   
wherein Y is an unsubstituted or substituted alkyl or arylalkyl group having 1 to 8 carbon atoms, as well as a process of preparing said compound.  The invention also provides a process of preparing the compound 3H,5H-pyrrolo[3,2-d]pyrimidin-4-one, comprising the step of reacting a compound of the formula (A) defined above with a reagent capable of delivering a formyl equivalent.  The invention also provides a process of preparing the compound 2-amino-3 H ,5 H -pyrrolo[3,2- d ]pyrimidin-4-one, comprising the step of reacting the compound 2-(N-dimethylaminomethylene)amino-6-(2-dimethylaminovinyl)-5-nitropyrimid-4-one with a reagent capable of reducing the nitro group, to produce the compound 2-amino-3 H ,5 H- pyrrolo[3,2- d ]pyrimidin-4-one.
Patent CA-2637677-A1 (CA)
Inventor: WITT MICHAEL RALPH JUERGEN
IPC: B27N3/04
Filed: 2006-12-22
Abstract: A process for producing a thermoformable fibre-plastics composite product comprising lignolcellulosic or natural fibres, particularly but not exclusively useful as an intermediate product in subsequent manufacture, comprises conveying the fibres in a dry or wet air stream and applying to the fibres a thermoplastic binding agent, and forming the fibres into a solid or semi-solid product such as a panel, which is thermoformable. In at least a preferred embodiment the process may be carried out in known plant for manufacture of medium density fibre board.
Patent CA-2641750-A1 (CA)
Inventor: BARTON JAMES
IPC: G06F3/00
Filed: 2007-02-06
Abstract: Techniques for recommending recording and/or downloading suggestions to a DVR  user are provided. According to one technique, a list of suggestions is received from a recommending entity. Each of the suggestions identifies either to-be-broadcasted content or downloadable content. The entity is mapped to the list, thereby establishing an entity-to-list mapping. Data, which indicates a user's selection of a list, is received. The user's DVR is mapped to the selected list, thereby establishing a DVR-to-list mapping. Based on this mapping, one or more candidate items are automatically selected from among a set of items. Identities of the candidate items are sent to the DVR. The recommending entity does not own or operate the DVR.
Patent CA-2642432-A1 (CA)
Inventor: CARNALI JOSEPH ORESTE
IPC: C11D1/10
Filed: 2007-02-23
Abstract: The invention relates to both compositions comprising flat platy particles wherein the particles individually have deposition system (i.e., cationic polymers and anionic surfactant) on them.
Patent CA-2642450-A1 (CA)
Inventor: ZAYAS BETTY JEAN
IPC: H01R13/64
Filed: 2007-02-15
Abstract: A lamp (32) is provided having terminal pins (48) mounted on and extending outwardly along a longitudinal axis of an end cap (44, 46) of the lamp (32). The pins (48) are offset relative to one another along the longitudinal axis. The end cap (44, 46) has semi-circular, parallel surfaces at one end, and the pins (48) extend outwardly from the respective semi-circular, parallel surfaces. A barrier wall (70a, 70b) extends substantially perpendicularly between the semi-circular surfaces. In a first embodiment, a male extension member (102) extends outwardly from the barrier wall along at least a portion of the lower semi-circular surface. This male extension is coextensive with the upper semi-circular surface. Alternatively, in a second embodiment, a female recess (118) is provided through the boundary wall. This recess again extends between the upper and lower semi-circular surfaces.
Patent CA-2649421-A1 (CA)
Inventor: HALL JOHN
IPC: G01J4/00
Filed: 2007-04-16
Abstract: A sensor and method for determining the optical properties of a sample material is disclosed. The sensor comprises a light source that generates a linearly polarized light beam having a predetermined polarization orientation with respect to the plane of incidence. The linearly polarized light beam is reflected off the sample and is split into second and third light beams where the second and third light beam consist of the combined projections of mutually orthogonal components of the first light beam. A signal processor measures the intensity difference between the second and third light beams to calculate the phase difference induced by the sample material.
Patent CA-2650857-A1 (CA)
Inventor: GRODZINS LEE
IPC: H05B33/00
Filed: 2007-05-25
Abstract: An instrument and method for measuring the elemental composition of a test material. The instrument has a source of penetrating radiation for irradiating an irradiated region of the test material, a detector for detecting fluorescence emission by the test material and for generating a detector signal, and a controller for converting the detector signal into a spectrum characterizing the composition of the test material. A platen of attenuating material extends outward from adjacent to, and surrounding, the irradiated surface of the test material. In certain embodiments, the thickness of the attenuating platen is tapered such as to decrease with increasing radial distance from the central irradiated region of the test material.
Patent CA-2651227-A1 (CA)
Inventor: CERDA BLAS
IPC: G01N33/68
Filed: 2007-05-04
Abstract: A substrate incorporating an internal standard facilitates quantitating analytes in a sample by surface-interrogating mass spectrometry techniques without wet chemistry sample preparation. The user disposes a sample to be analyzed onto the surface of the pretreated substrate. Then the sample-bearing solid substrate, which incorporates an internal standard for each analyte to be quantitated, is ready for interrogation.
Patent CA-2651562-A1 (CA)
Title: Gerotor motor and brake assembly
Inventor: WHITE HOLLIS N JR
IPC: F01C1/02
Filed: 2007-05-02
Abstract: A hydraulic device includes a gerotor assembly, a wobble stick, an output shaft, a housing assembly, a first port in the housing assembly, a second port in the housing assembly, first brake disks, second brake disks, a piston, and a biasing member. The gerotor assembly includes a rotor and a stator. The wobble stick connects at a first end to the rotor. The output shaft connects to a second end of the wobble stick The housing assembly receives the gerotor assembly, the wobble stick and the output shaft. The first port is in communication with the gerotor assembly. The second port is also in communication with the gerotor assembly. The first brake disks connect to the output shaft The second brake disks connect to the housing assembly. The piston is disposed in the housing assembly adjacent at least one of the brake disks.
Patent CA-2651955-A1 (CA)
Title: Oil sensor placement structure in engine
Inventor: UESHIMA HIDEO
IPC: F02B77/00
Filed: 2007-04-11
Abstract: In an engine, an oil level sensor (47) provided at the bottom of an oil pan (15) that contains engine oil and upstanding upward in the vertical direction is placed between a pair of balancer shafts (27, 28) that are received in parallel to each other in a balancer housing (21) provided between the lower surface of a cylinder block and the oil pan (15). A dead space formed between the pair of balancer shafts (27, 28) is effectively used to allow the oil level sensor (47) to be compactly received. Also, the pair of balancer shafts (27, 28) suppress agitation of the engine oil to prevent degradation of detection accuracy caused by splash of the oil on the oil level sensor (47).
Patent CA-2653247-A1 (CA)
Title: Methods for selective n-9 glycosylation of purines
Inventor: ZHONG MINGHONG
IPC: A61K31/70
Filed: 2006-06-14
Abstract: A process for providing regiospecific and highly stereoselective synthesi s of 9-.beta. anomeric purine nucleoside analogs is described. The introduct ion of the sugar moiety on to 6-(azolyl)-substituted purine bases is perform ed so that highly stereoselective formation of the .beta. anomers of only th e 9 position regioisomers of the purine nucleoside analogs (either D or L en antiomers) is obtained. This regiospecific and stereoselective introduction of the sugar moiety allows the synthesis of nucleoside analogs, and in parti cular 2'-deoxy, 3'-deoxy, 2'-deoxy-2'-halo-arabino and 2',3'-dideoxy-2'-halo -threo purine nucleoside analogs, in high yields without formation of the 7- positional regioisomers. Processes for providing novel 6-(azolyl)purines for the regiospecific and highly stereoselective synthesis of 9-.beta. anomeric purine nucleoside analogs are described. The compounds are drugs or interme diates to drugs.
Patent CA-2655040-A1 (CA)
Inventor: IKING RUDOLF
IPC: C10M129/78
Filed: 2007-06-02
Abstract: Proposed are lubricant compounds with a good shear stability defined by the loss of the kinematic viscosity at 100 °C, containing base oil and a synthetic complex ester, the complex ester having a kinematic viscosity at 40°C of greater than 400 and up to 50,000 mm2/s and being obtained by conversion of a) polyols and monocarbonic acids and dicarbonic acids, or of b) polyols and mono-alcohols and dicarbonic acids, or of c) polyols and mono-alcohols and monocarbonic acids and dicarbonic acids. In addition the use of the said lubricant compounds containing the complex esters as oils for vehicle transmission, axles, industrial drives, compressors, turbines or engines is proposed.
Patent CA-2656157-A1 (CA)
Inventor: KIM OAK K
IPC: C07D235/22
Filed: 2007-06-25
Abstract: Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.
Patent CA-2659381-A1 (CA)
Title: Method for economic valuation in seismic to simulation workflows
Inventor: BOUZAS HORACIO R
IPC: G06F9/455
Filed: 2007-08-30
Abstract: A method is disclosed for performing economic calculations in petro-technical workflows, comprising: designing an economic model including, building and running an economic calculation, the building and running step including, opening an economics dialog box, clicking an economics calculation tab in the economics dialog box, clicking a settings tab in the economics dialog box and configuring a set of settings for the economic calculation, and clicking a run button in the economics dialog box to perform the economic calculation.
Patent CA-2661443-A1 (CA)
Inventor: MAUCKSCH THOMAS
IPC: H04W24/06
Filed: 2007-04-26
Abstract: The invention regards a system, a mobile communication unit (3) and a met hod for analysing a receiver (8) performance of a mobile communication unit (3). An information is generated in a system simulator (4) and is transmitte d in a transmission signal from a testing device (2) to a mobile communicati on unit (3) under test. The transmission signal is transmitted from the test ing device (2) to the mobile communication unit (3) under test via a unidire ctional channel (6, 7). The transmission signal is received and analyzed by the receiver (8) the performance of which is to be tested. By analyzing the received transmission signal the information included in the transmission si gnal is being obtained. The information obtained from the analysis of the tr ansmission signal is transmitted back from the mobile communication unit (3) under test in a backtransmission signal via an independent backtransmission channel (14). The backtransmission signal received by the testing device (2 ) is analysed by the testing device (2) for obtaining the information includ ed in the backtransmission signal and the result is compared to the informat ion originally generated.
Patent CA-2662655-A1 (CA)
Inventor: LAWTON KAY A
IPC: C12Q1/00
Filed: 2007-09-18
Abstract: Methods for identifying and evaluating suites of biochemical and/or gene entities useful as biomarkers for early prediction of prostate cancer, disease grading, target identification/validation, and monitoring of drug efficacy are provided. Also provided are suites of small molecule entities as biomarkers for prostate cancer.
Patent CA-2664261-A1 (CA)
Inventor: DEBUT ALEXIS
IPC: C03C25/47
Filed: 2006-09-25
Abstract: A buffered optical fibre comprising an optical waveguide, at least one exterior coating (2) surrounding said optical waveguide (1) and a buffer coating (4) surrounding said at least one exterior coating (2, 3), wherein the said buffer coating is a tight buffer coating made of a material having a density of at least 1.2 Kg/dm3, a thermal conductivity of at least 0.4 W/m.K and comprising a polymeric matrix and an inorganic filler.