baber/WOPTO huggingface dataset:
Patent CA-2750449-A1 (CA)
Inventor: MAYER STANISLAS
IPC: A61K31/437
Filed: 2010-01-25
Abstract: The present invention provides new compounds with high affinity for adenosine A 2A receptors. It also provides antagonists of adenosine A 2A receptors and their use as medicaments for the treatment and/or prophylaxis of diseases and disorders where the partial or total inactivation of adenosine A 2A receptors signalling pathways could be beneficial such as Alzheimer's disease, Parkinson's disease, attention deficit and hyperactivity disorders (ADHD), Huntington's disease, neuroprotection, schizophrenia, anxiety and pain. The present invention further relates to pharmaceutical compositions containing such new compounds with high affinity for adenosine A 2A receptors and their use for the treatment and/or prophylaxis of diseases and disorders where the partial or total inactivation of adenosine A 2A receptors could be beneficial.
Patent CA-2751230-A1 (CA)
Title: Procedes et dispositifs permettant la realisation d'une gastroplastie
Inventor: GAGNER MICHEL
IPC: A61B17/03
Filed: 2009-01-30
Abstract: La présente invention concerne un procédé de gastroplastie mettant en uvre une rangée d'agrafes qui se termine avant d'atteindre la jonction gastro-sophagienne de sorte que la partie contournée de l'estomac ne nécessite aucune résection. En outre, de bougies tendues aident un physicien à suivre la rangée d'agrafes selon la présente invention.
Patent CA-2751322-A1 (CA)
Inventor: WIKSTROEM HAKAN
IPC: A61P25/16
Filed: 2010-02-26
Abstract: Disclosed herein are methods of treating Parkinsons disease while maintaining a low dyskinesia induction profile and methods of reversing dyskinesias comprising administering a therapeutically effective amount of a compound of the invention. The present invention further relates to uses and pharmaceutical compositions of said compounds in the manufacture of medicaments in treating the same.
Patent CA-2755910-A1 (CA)
Title: Polycyclic compounds as inhibitors of nf-kb
Inventor: ZHANG JIE
IPC: C07D303/36
Filed: 2010-03-25
Abstract: The invention relates to compounds of formulae (1) and (2), and pharmaceutically acceptable salts thereof for the treatment of cancer, inflammation, auto-immune diseases, diabetes and diabetic complications, infection, cardiovascular disease and ischemia-reperfusion injuries.
Patent CA-2759534-A1 (CA)
Title: Method for determining maternal health risks
Inventor: KYPROS NICOLAIDES
IPC: G01N33/74
Filed: 2010-04-23
Abstract: The present description relates to a method for determining the risk of a pregnant woman developing a hypertensive disorder, more specifically gestational hyper-tension or late onset preeclampsia. The present description provides methods useful for determining risk that a pregnant individual will develop a hypertensive disorder or condition of pregnancy, such as gestational hypertension, early preec-lampsia, late preeclampsia and related disorders. Several useful combinations of biochemical markers and related clinical population studies are described herein.  Additionally, it is proposed herein that certain sets of biochemical markers can be used to determine risk of multiple hypertensive disorders in a single screen. The biochemical markers are P1GF, Activin A and optionally P-Selectin.
Patent CA-2762022-A1 (CA)
Inventor: LINDSAY DEREK
IPC: C07D317/28
Filed: 2010-05-17
Abstract: The present invention provides redox drug derivatives. In particular, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, (3R, 4R, 5S)-4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester, (3S)-3-(aminomethyl)-5-methylhexanoic acid, (3S)-1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-.alpha.-.alpha.-diphenyl-3-pyrrolidineacetamide, (1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethyl-butyl]-4-(diaminomethylideneamino)-2-hydroxy-cyclopentane-1-carboxylic acid and (2R,3R,4S)- 4-[(diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4- dihydro-2H-pyran-6-carboxylic acid redox derivatives.
Patent CA-2763794-A1 (CA)
Inventor: EUTENEUER CHARLES L
IPC: A61B17/068
Filed: 2010-06-04
Abstract: Devices for attaching a sheet-like implant to a target tissue include a sheath and a staple push rod. The sheath has a distal end configured to be pressed against the target tissue. The staple push rod is disposed within at least a portion of the sheath and is slidable relative thereto. The staple push rod includes a pair of stakes. Each stake is dimensioned to abut a surface of a staple to apply pushing forces thereto. The stakes are biased to assume a bow-like shape such that an intermediate portion of a staple extends tautly between the first stake and the second stake when the stakes are extending beyond the distal end of the tubular member. Methods for attaching a sheet-like implant to a target tissue are also disclosed.
Patent CA-2764642-A1 (CA)
Title: Taste masking spill-resistant formulation
Inventor: MOROS DANIEL A
IPC: A61K47/34
Filed: 2002-10-22
Abstract: A spill resistant pharmaceutical formulation for oral administration, comprising a pharmaceutical agent and a spill resistant base, the pharmaceutical agent or base being bitter in the absence of taste masking, and a bitterness masking component consisting essentially of low-weight polyethylene glycol (PEG) in a concentration from about 1% to about 15% wt/wt.
Patent CA-2765287-A1 (CA)
Title: Nicotiana benthamiana plants deficient in xylosyltransferase activity
Inventor: WETERINGS KOEN
IPC: C12N9/10
Filed: 2010-06-10
Abstract: The invention provides Nicotiana benthamiana mutant plants which are incapable of forming xylosyl-structures on glycoproteins. In addition, the invention provides methods for the production of heterologous glycoproteins in said mutant plants.
Patent CA-2766703-A1 (CA)
Inventor: SMIT FRANCISCUS PETRUS
IPC: C12Q1/68
Filed: 2010-06-22
Abstract: The present invention relates to methods for establishing the presence, or absence, of a kidney, or renal, tumour in a human individual suspected of suffering from kidney, or renal, cancer. Specifically, the present invention relates to methods for establishing the presence, or absence, of a kidney tumour in a human individual suspected of suffering from kidney cancer comprising: a) determining the expression of one or more genes chosen from the group consisting of NDUFA412, ANGPTL4, EGLN3, PTHLH, and ATP6V1B1 in a sample originating from said human individual; b) establishing up, or down, regulation of expression of said one or more genes as compared to expression of said respective one or more genes in a sample originating from said human individual not comprising kidney tumour cells or tissue, or from an individual, or group of individuals, not suffering from kidney cancer;and c) establishing the presence, or absence, of a kidney tumour based on the established up-or down regulation of said one or more genes.
Patent CA-2768368-A1 (CA)
Title: Deuterated 2, 4-pyrimidinediamine compounds and prodrugs thereof and their uses
Inventor: BHAMIDIPATI SOMASEKHAR
IPC: A61P37/08
Filed: 2010-07-16
Abstract: The present disclosure provides biologically active deuterated 2,4-pyrimidinediamine compounds <1> Formula (1) and prodrugs thereof, compositions comprising the deuterated compounds, intermediates and methods for synthesizing the deuterated compounds and methods of using the deuterated compounds in a variety of applications.
Patent CA-2771698-A1 (CA)
Inventor: LEWIS SAM
IPC: E21B33/13
Filed: 2010-08-20
Abstract: The present disclosure is directed to a system and method for managing cement in a subterranean zone. In some implementations, a method of cementing in a subterranean formation includes positioning a cement slurry including a plurality of activation devices in a wellbore. The activation devices configured to release an activator that increases a setting rate of the cement slurry. A signal is transmitted to at least a portion of the cement slurry to activate the activation devices. The activation device releases the activator in response to at least the signal.
Patent CA-2771883-A1 (CA)
Title: Transmission method of downlink signal in wireless communication system and transmission apparatus therefor
Inventor: KWON YEONG HYEON
IPC: H04B7/26
Filed: 2010-08-23
Abstract: The present invention provides a method for a base station to transmit a downlink signal in a wireless communication system, the method comprising: allocating a resource to a downlink signal; and transmitting the downlink signal using the allocated resource. In the downlink signal transmission method and apparatus thereof, a resource for transmitting a Physical Downlink Shared Channel (PDSCH) among the downlink signals is allocated from a specific OFDM symbol that is fixed within a subframe.
Patent CA-2772248-A1 (CA)
Inventor: RUBINSZTAJN SLAWOMIR
IPC: C12N5/02
Filed: 2010-09-27
Abstract: Methods and kits of releasing cells are provided. The method comprises the steps of providing cultured cells on a cell culture support comprising a multi layer polyelectrolyte coating immobilized on a substrate, and releasing the cultured cells from the cell culture support by a releasing solution comprising DMSO. The kit comprises a cell culture support and a releasing solution. The cell culture support comprises a substrate and a multi layer polyelectrolyte coating immobilized on the substrate and the releasing solution comprises DMSO.
Patent CA-2772422-A1 (CA)
Title: Audio/video and data signal redistribution system
Inventor: JEFFERY ROSS A
IPC: H04N21/25
Filed: 2001-03-09
Abstract: A system for routing an output signal containing a selected program to a user comprises a server inserting and/or substituting programming other than the selected program into the output signal containing the selected program, based on user information relating to the user.
Patent CA-2772681-A1 (CA)
Inventor: ZHU GUOLIANG
IPC: C07C233/47
Filed: 2010-03-23
Abstract: A novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors.
Patent CA-2773481-A1 (CA)
Title: Seed pans
Inventor: DIETRICH DAVE
IPC: A01D75/02
Filed: 2010-09-23
Abstract: A seed pan apparatus has an elongated seed pan plate with parallel right and left edges, a curved configuration and a pointed front end. An engagement mechanism attaches the plate to a harvester cutting header such that the plate is above two adjacent guard fingers, such that an open slot is defined between the right edge of one plate and the left edge of an adjacent plate and the edges of the slot are in proximity to the outer edges of the guard fingers under the adjacent plates. The point is offset to make one front tapering edge forming the point longer than the other, and smooths the passage of stalks into the slot. The inclination, height, and fore and aft position of the seed pan plate can be adjusted to suit varying conditions of crop, moisture, soil, and the like or to suit different harvesting machines.
Patent CA-2774008-A1 (CA)
Title: Toll-like receptor modulators and uses thereof
Inventor: YIN HANG
IPC: A61P3/10
Filed: 2010-09-23
Abstract: The present invention provides a compound selected from the group consisting of: Formula (I) and Formula (II), where n, m, X1, X2, X3, X4, R1, R2, R3, R11, R12, Y1, Y2, Y3, Y4, and Y5 are those defined herein. Some aspects of the invention also provides methods for using these compounds and compositions comprising the same.
Patent CA-2775654-A1 (CA)
Inventor: BUCKNALL DAVID
IPC: A61L31/04
Filed: 2010-11-01
Abstract: This invention relates to a tissue expander for use in medical, veterinary and dental applications. The tissue expander comprises a self-inflating polymer network and a biodegradable polymer having a non-degraded state and a degraded state which in the non- degraded state constrains the inflation of the self-inflating polymer network and in the degraded state allows inflation of the self-inflating polymer network. In a preferred embodiment, the self-inflating polymer network and the biodegradable polymer form an interpenetrating polymer network or a semi-interpenetrating polymer network. Alternatively or in addition, the self-inflating polymer network forms a core and the biodegradable polymer forms coating which partially or fully surrounds the core.
Patent CA-2776492-A1 (CA)
Inventor: SANDERS JOHN LARRY
IPC: C05D3/00
Filed: 2010-09-24
Abstract: Improved fertilizer mineral compositions are provided by coating a mineral, such as gypsum, a member of the Kieserite Group, potassium magnesium sulfate, elemental sulfur, and mixtures thereof, with low pH maleic-itaconic copolymers. The preferred copolymers are aqueous dispersions of acid or partial salt maleic-itaconic copolymers, and are applied by spraying or other means onto the surface of the mineral and allowed to dry. The copolymer coatings increase the solubility of sulfate and calcium or magnesium ions from the fertilizer minerals, allowing accelerated plant availability and uptake of such nutrients.
Patent CA-2777406-A1 (CA)
Inventor: CHEN CHING-SHIH
IPC: A61P35/00
Filed: 2010-10-11
Abstract: A method of inhibiting glycolysis in a subject by administering a pharmaceutical composition including a thiazolidinedione derivative to the subject is described. The thiazolidinedione derivatives are effective energy restriction mimetic agents, and can therefore be used to treat or prevent cancer in a subject, treat metabolic disorder, or increase the longevity of a subject. Various thiazolidinedione derivatives are also suitable for activating adenosine phosphate-activated protein kinase or inhibiting IL-6 expression.
Patent CA-2779696-A1 (CA)
Inventor: HIRSCH JAMES A
IPC: A61C17/032
Filed: 2010-11-04
Abstract: An air water vacuum dental instrument includes a handle; a head; an air control carried by at least one of the handle and the head; a water control carried by at least one of the handle and the head; a vacuum control carried by at least one of the handle and the head; and an air water vacuum tip coupled to the head and configured to provide at least air, water, and vacuum in a mouth of a dental patient at the air water vacuum tip.
Patent CA-2782053-A1 (CA)
Inventor: SPRINGER STACY
IPC: H05B3/34
Filed: 2010-09-01
Abstract: A band heater assembly for heating an object includes a band heater that extends around at least a portion of a perimeter of the object. The band heater includes a cable and a band. The cable includes a resistive element, a first cable end and a second cable end. The resistive element generates thermal energy based on a current received from a power source. The first cable end and the second cable end are connected to respective ends of the band heater assembly. The band is connected to the cable and transfers a first portion of the thermal energy to an exterior surface of the object. At least a portion of the cable is exposed from the band heater to contact the exterior surface when the band heater assembly is connected to the object.
Patent CA-2783215-A1 (CA)
Title: Limnanthes oil genes
Inventor: CAHOON EDGAR B
IPC: C11B1/00
Filed: 1999-03-12
Abstract: This invention relates to an isolated nucleic acid fragment encoding an enzyme involved in lipid biosynthesis. The invention also relates to the construction of a chimeric gene encoding all or a portion of the enzyme involved in lipid biosynthesis, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the enzyme involved in lipid biosynthesis in a transformed host cell.
Patent CA-2783299-A1 (CA)
Title: Apparatus for detecting chemical substances
Inventor: SATO TOMOYOSHI
IPC: G01N27/62
Filed: 2010-12-22
Abstract: An olfactory system (300) which can detect a threat is provided with: a detection unit (100) including an IMS sensor (110) which outputs IMS data (115) relating to chemical substances included in fluid at a sampling point; a local memory (41) storing a library (49) which includes a specific pattern (48) generated when a specific chemical substance was detected by the IMS sensor (110); and a collation unit (42) for constantly comparing and collating the IMS data (115) and the specific pattern (48) for monitoring that is included in the library (49).
Patent CA-2784098-A1 (CA)
Title: High-throughput methods and systems for processing biological materials
Inventor: GRIFFIN WESTON BLAINE
IPC: B01D21/26
Filed: 2010-12-15
Abstract: A high-throughput system for processing biological material that comprises: a tray that supports a functionally-closed fluid path subsystem comprising, a vessel for containing and enabling the biological material to separate into two or more distinct submaterials; one or more receptacles to receive one or more of the submaterials from the vessel; a filtration device; a conduit through which one or more submaterials are transported between at least the vessel and the filtration device; and a first engagement structure; a processing unit comprising, a pumping device for moving one or more of the submaterials between at least the vessel and the filtration device via the conduit; a second engagement structure corresponding to the first engagement structure; a locking mechanism for at least temporarily holding the tray in a fixed position relative to the processing unit; a control device that automatically starts and stops the pumping device in response to one or more commands.
Patent CA-2786475-A1 (CA)
Inventor: LIAO YIN-HSI
IPC: A63H33/18
Filed: 2012-08-16
Abstract: The toy gun contains a power element electrically connected with a driver element and an electronic fire-control assembly. The electronic fire-control assembly turns on or off the driver element, which in turn engages or disengages a gear set. When the trigger is pulled, the electronic fire-control assembly controls the power element to provide electricity to the driver element which in turn engages the gear set to conduct firing. The electronic fire-control assembly incorporates a magazine detection module, a shot selection module, and a trigger on/off module. When one of the functions breaks down, a user just replaces the electronic fire-control assembly, instead of spending time and effort to inspect, disassemble, and re-assemble the toy gun.
Patent CA-2789453-A1 (CA)
Inventor: TURKKI TARJA
IPC: D21H17/70
Filed: 2011-02-10
Abstract: The invention relates to a process for the preparation of a pigment -cellulosic fibre composite, wherein the pigment comprises an inorganic pigment which comprises local cationic charges, said process comprises contacting an aqueous cellulosic fibre suspension and inorganic pigment particles such that crystals of said pigment are attached to the surface of the fibre, said crystals having a size of at most 5 µm. The produced composite product can be used as a filler pigment or coating pigment in the production of paper.
Patent CA-2790063-A1 (CA)
Title: Oxidation stability using natural antioxidants
Inventor: LIS DANIEL G
IPC: A23L29/00
Filed: 2009-12-17
Abstract: A method of preparing an egg yolk with reduced pro-oxidant properties comprising: (1) providing a volume of egg yolk containing iron; (2) removing iron-rich phosvitin from the egg yolk resulting in an iron-reduced egg yolk, wherein the phosvitin has a protein structure, and removing the iron-rich phosvitin from the egg yolk does not substantially disrupt the phosvitin structure; (3) suspending the iron-rich phosvitin in an aqueous solution to form a phosvitin suspension; (4) centrifuging or filtering the phosvitin suspension to form an iron-reduced phosvitin; and (5) washing the iron-reduced phosvitin with water to form a washed phosvitin suspension having a reduced iron level to form an iron-reduced phosvitin.
Patent CA-2791805-A1 (CA)
Inventor: JOHNSTON LAURA
IPC: A61K31/5415
Filed: 2010-03-03
Abstract: The invention is directed to the use of a formulation comprising meloxicam or a pharmacologically acceptable meloxicam salt of an organic or inorganic base thereof for the long-term treatment of musculoskeletal disorders in cats. No negative effects on renal function occur following a treatment from 10 to 20 months or more.
Patent CA-2793542-A1 (CA)
Inventor: NORRGA STEFAN
IPC: H02M7/797
Filed: 2010-03-18
Abstract: A cascaded electric power converter and a method of operating a cascaded electric power converter are disclosed. The cascaded converter comprises: a converter cell including a cell capacitor and at least one phase leg having at least two electric valves, the at least one phase leg being connected in parallel to the cell capacitor; and a control system for controlling the switching of the electric valves of the at least one phase leg. The control system is configured to, upon detection of a need to by-pass the converter cell, control the switching of the electric valves in a manner so that the cell capacitor is short circuited via a phase leg, so as to obtain a current surge through the phase leg, thereby creating a permanent current path through the converter cell.
Patent CA-2794763-A1 (CA)
Inventor: WIEMANN SCOTT HARVEY
IPC: G06F17/30
Filed: 2011-03-28
Abstract: A system for use in editorial review of stored information includes a web interface (112) adapted to provide a graphical user interface to a user. A first application component (114-1) is adapted to run in the web interface (112). The first application component (114-1) includes a first user interface component (150) adapted to present information to a user (120) and receive editorial content related to the information from the user (120). A  first database communication component (152) is adapted to communicate with a database (106) containing the stored information and editorialize the stored information in the database (106) in response to the editorial content received from the user (120). A first communication component (154) is adapted to communicate within the web interface (112) in response to the editorial content received from the user. A second application component is adapted to run in the web interface. The second application component (114-2) includes a second user interface component (150) adapted to present information to the user and receive editorial content related to the information from the user. A second communication component (154) is adapted to communicate with first communication component (154). A second database communication component (152) communicates with the database (106) containing the stored information based upon data received from the first application component (114-1, 114-2) in response to the editorial content received from the user (120).
Patent CA-2794888-A1 (CA)
Title: Gas turbine engine architecture with low pressure compressor hub between high and low rotor thrust bearings
Inventor: DAVIS TODD A
IPC: F02C7/36
Filed: 2012-11-07
Abstract: A gas turbine engine has a low pressure compressor, a first bearing system supporting an inner shaft, a second bearing system supporting an outer shaft, and a low pressure compressor hub mounted to the inner shaft. The low pressure compressor hub extends to the low pressure compressor between the first and second bearing systems and supports a plurality of stages of the low pressure compressor. Locating the low pressure hub between the bearings offers advantages to reduce deflection for a geared architecture.
Patent CA-2798684-A1 (CA)
Inventor: PROCIW PHILIP JAMES
IPC: H04M1/72412
Filed: 2012-12-11
Abstract: La présente divulgation fournit une station d'accueil servant à accueillir un ou plusieurs dispositifs électroniques, comme une tablette et un téléphone mobile ou intelligent. La présente divulgation fournit une méthode de changement de modes fonctionnels dun dispositif électronique branché à une station d'accueil, ainsi quun dispositif électronique et une station d'accueil configuré pour ce dispositif.