baber/WOPTO huggingface dataset:
Patent NZ-610230-A (NZ)
Title: Compositions and methods for treating ocular edema, neovascularization and related diseases
Inventor: PETERS KEVIN G
IPC: A61P27/00
Filed: 2011-10-05
Abstract: Disclosed is the use of a compound for manufacturing a medicament for treating age-related macular degeneration, where the compound is within the general formula depicted. Also disclosed are compositions comprising HPTP-beta inhibitors suitable for treating eye diseases and conditions. Examples of compounds disclosed are: 4-{ (S)-2-(4-Ethylthiazol-2-yl)-2-[(S)-2-(methoxycarbonylamino)-3-phenylpropanamido]ethyl} phenylsulfamic acid; 4-{ (S)-2-[(5)-2-(Methoxycarbonylamino)-3-phenylpropanamido]-2-[4-(thiophen-2-yl)thiazol-2-yl] ethyl} pheaylsulfamic acid; 4-{ (S)-2-[(S)-2-(Methoxycarbonylamino)-3-phenylpropanamido]-2-(2-ethylthiazol-4-y1) ethyl} phenylsulfamic acid and 4-{ (S)-2-[(S)-2-(Methoxycarbonylamino)-3-phenylpropanamido]-2-[2-(thiophen-2-yl)thiazol-4-yl]ethyl} phenylsulfamic acid. Further disclosed are methods for the treatment of diseases or conditions of the eye with HPTP-beta inhibitors, especially retinopathies, ocular edema and ocular neovascularization. Non-limiting examples of these diseases or conditions include diabetic macular edema, age-related macular degeneration (wet form), choroidal neovascularization, diabetic retinopathy, retinal vein occlusion (central or branch), ocular trauma, surgery induced edema, surgery induced neovascularization, cystoid macular edema, ocular ischemia, uveitis, and the like.
Patent NZ-616594-A (NZ)
Title: Antibodies to opgl
Inventor: DAVIS GEOFFREY C
IPC: A61P19/10
Filed: 2002-06-25
Abstract: 616594 Discloses a polynucleotide or polypeptide which interacts with an osteoprotegerin ligand (OPGL) comprising a heavy chain of residue 20-467 of SEQ ID NO: 2 and a light chain comprising SEQ ID NO: 14 or a light chain of residues 21-235 SEQ ID NO: 4 and a heavy chain comprising SEQ ID NO: 13 or a heavy chain of residue 20-467 of SEQ ID NO: 2 and a light chain of residues 21-235 SEQ ID NO: 4 or a heavy chain comprising SEQ ID NO: 13 and a light chain comprising SEQ ID NO: 14.
Patent NZ-617828-A (NZ)
Title: Controlled release peptide formulations
Inventor: TIBERG FREDRIK
IPC: A61K47/24
Filed: 2012-05-25
Abstract: The disclosure relates to pre-formulation compositions comprising a low viscosity mixture of 20 - 80 wt.% of at least one diacyl glycerol and/or a tocopherol; b) 20-80 wt. % of at least one phosphatidyl choline (PC); c) 5-20 wt. % of at least one biocompatible, organic mono-alcoholic solvent; d) up to 20 wt.% polar solvent e) at least one peptide active agent; f) optionally at least one antioxidant; wherein the ratio of components a:b is in the range 40:60 to 54:46; wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with excess aqueous fluid. The peptide active agent may be a somatostatin analogue selected from somatostatin 14, somatostatin 28, octreotide, lanreotide, pasireotide and vapreotide and the antioxidant may be ascorbic acid, EDTA or citric acid. The disclosure also relates to the use of these compositions to treat diseases, including cancer, and pre-filled administration devices and kits containing the formulations.
Patent NZ-623122-A (NZ)
Title: Mechanical prosthetic heart valve
IPC: A61F2/24
Filed: 2008-04-30
Abstract: Mobile flap (18) intended to be mounted on an annular support of a mechanical prosthetic heart valve. The flap (18) has at its periphery a leading edge (44) that is intended to be disposed on the upstream side of the anterograde blood flow and a trailing edge (46) that is intended to be disposed on the downstream side of that flow. A central part (38) is symmetrically bracketed by two lateral wings (40, 42) that are inclined relative to the central part (38), each lateral wing (40, 42) being joined to the central part (38) by a junction area the exterior surface of which is convex and which, over at least part of its length including the trailing edge, has a radius of curvature in line with the trailing edge that is at least 2 mm for a valve intended to be implanted to the aortic position and at least 3 mm for a valve intended to be implanted in the mitral position. The central portion has a convex exterior and concave interior.
Patent NZ-628693-A (NZ)
Title: Cyclone separation device and electric vacuum cleaner
Inventor: MAEDA TSUYOSHI
IPC: A47L9/16
Filed: 2012-07-03
Abstract: A dust collection unit is provided with a swirl chamber (29), dust collection chambers (30, 31), a discharge pipe (57), an inlet pipe (35), a bypass inlet opening (41), and a bypass inlet air flow passage (28). The swirl chamber (29) swirls dust-containing air along the side wall and separates dust from the dust-containing air, the dust containing air having entered from a primary inlet opening (40) and from a secondary inlet opening (42) which has a smaller opening area than the primary inlet opening (40). The dust separated by the swirl chamber (29) is captured by the dust collection chambers (30, 31). A discharge opening (54) is formed in the discharge pipe (51). The inlet pipe (35) allows the dust-containing air to flow from the primary inlet opening (40) to the swirl chamber (29). The bypass inlet opening (41) is formed in the inlet pipe (35). The bypass inlet air flow passage (28) allows the dust-containing air within the inlet pipe (35), the dust-containing air having flowed from the bypass inlet opening (41), to flow from the secondary inlet opening (42) to the swirl chamber (29).
Patent NZ-701916-A (NZ)
Title: Methods and arrangements for csi reporting
Inventor: HAMMARWALL DAVID
IPC: H04L5/00
Filed: 2013-05-07
Abstract: Some embodiments provide a method in a wireless device for reporting channel state information, CSI, for a CSI process. The CSI process corresponds to a reference signal resource and an interference measurement resource. According to the method, the wireless device obtains (810) an adjustment value associated with the CSI process. The wireless device estimates (820) an effective channel based on one or more reference signals received in the reference signal resource, and applies (830) the adjustment value to the estimated effective channel, thereby obtaining an adjusted effective channel. Furthermore, the wireless device determines (840) channel state information based on the adjusted effective channel, and on interference estimated based on the interference measurement resource. Finally, the channel state information is transmitted (850) to a network node.
Patent NZ-708361-A (NZ)
Title: Thermal energy storage comprising an expansion space
Inventor: PILERBO HANS
IPC: F28D20/00
Filed: 2013-11-01
Abstract: A need has been identified for improved efficiency in storage of thermal energy within the area of modern energy technology. Thermal energy may advantageously be stored in a fluid, such as e.g. water, above ground in insulated tanks, in ground in insulated pits, or underground in excavated caverns, using the surrounding ground as insulation. While existing solutions have their place, improved arrangements for storing thermal energy underground are always sought. A new arrangement for storing thermal energy is disclosed. In at least one embodiment, the new arrangement comprises a shaft (1) and at least one tunnel (2), the shaft (1) and the at least one tunnel (2) being in fluid communication with each other. The tunnel (2) comprises at least a first (2a), a second (2b), and a third (2c) tunnel section. The second tunnel section (2b) is arranged between and connected to the first (2a) and third (2c) tunnel sections. The second tunnel section (2b) is sealed off at an end (4) connected to the third tunnel section (2c), and the third tunnel section is further connected the shaft (1). The shaft (1) and first (2a) and third (2c) tunnel sections are adapted for holding fluid for thermal storage. The second tunnel section (2b) is adapted for use as an expansion space should a volume of the fluid expand beyond a volume of the shaft (1) and the first (2a) and third (2c) tunnel sections. The arrangement further comprises a first transfer means (5) for passing the expanded fluid volume from the shaft (1) and/or the third tunnel section (2c) into the first tunnel section (2a), and/or for passing fluid from the first tunnel section to the third tunnel section and/or the shaft. A second transfer means (6) is provided for passing the expanded fluid volume from the first tunnel section (2a) to the second tunnel section (2b). Embodiments arranged in accordance with the latter may serve to provide an environmentally friendly arrangement for storing thermal energy underground, provide improved arrangements for storing thermal energy having sufficient expansion and safety space without incurring unnecessary construction or operating costs, and/or provide arrangements wherein any fluid located within the expansion and safety space can be used in the thermal energy storing cycle.
Patent NZ-710335-A (NZ)
Title: Folding rule and method for measuring angles
Inventor: NEUGÄRTNER MARIO
IPC: G01B3/56
Filed: 2014-02-04
Abstract: The invention relates to a folding rule (G) which comprises at least four sections (1, 2, 3, 4) that are hinged together, at least the fourth section (4) having two scales (SK1, SK2) for angle measurement and the first section (1) having at least one reading mark (M). The first scale (SK1) for angle measurement and the reading mark (M) are located on the respective section (4, 1) such that the reading mark (M) points to the value of the first scale (SK1), which corresponds to the angle (α) to be measured between the sides (O1, O2) that rest on the second section (2) or on the fourth section (4) when the first section (1) and the fourth section (4) are aligned in parallel and a first lateral edge (1.1) or a second lateral edge (1.2) of the first section (1) rests on a first lateral edge (4.1) of the fourth section (4). The second scale (SK2) for angle measurement and the reading mark (M) are located on the respective section (4, 1) such that the reading mark (M) points to the value of the second scale (SK2), which corresponds to the angle (α) to be measured between the sides (O1, O2) that rest on the third section (3) or on the fourth section (4) when the first section (1) and the fourth section (4) are aligned in parallel and a second lateral edge (1.2) of the first section (1) rests on a second lateral edge (4.2) of the fourth section (4). The invention further relates to a method for angle measurement by means of the folding rule (G).
Patent NZ-713004-A (NZ)
Title: Apparatus and method of monitoring moving objects
Inventor: TAKIGUCHI MASAHIRO
IPC: H04N7/18
Filed: 2014-03-10
Abstract: A monitoring area is scanned by an area sensor device (e.g., an optical distance meter) to detect objects (step C2). Moving objects are identified among the detected objects (step C3), and, among the identified moving objects, a moving object which is present in the monitoring area and which has been newest identified is set as a tracking target (step C4). The moving object which has been set at the tracking target is automatically tracked by a camera device (step C5-C13). As a result, even if there are present a plurality of moving objects in the monitoring area, tracking targets can be switched from one to another, so that it is possible to designate, as a tracking target, a moving object desired by an observer.
Patent NZ-715583-A (NZ)
Title: Influenza virus vaccines and uses thereof
Inventor: MEIJBERG JAN WILEM
IPC: C12N15/63
Filed: 2014-05-27
Abstract: The present invention provides influenza hemagglutinin stem domain polypeptides comprising (a) an influenza hemagglutinin HA1 domain that comprises an HAl N-terminal stem segment, comprising the amino acids from position 1 to position x, preferably from position p to position x, of the HA1 domain, covalently linked by a linking sequence of 0-50 amino acid residues to an HA1 C- terminal stem segment, comprising the amino acids from position y to and including the C-terminal amino acid of the HA1 domain and (b) an influenza hemagglutinin HA2 domain, wherein the hemagglutinin stem domain polypeptide is resistant to protease cleavage at the junction between HA1 and HA2, and wherein one or more amino of the amino acids at positions 337, 340, 352, 353, 402, 406, 409, 413 and/or 416 have been mutated as compared to the corresponding positions in wild-type influenza HA.
Patent NZ-719650-A (NZ)
Title: Rotary battery switch
Inventor: WILKINS CHRISTOPHER
IPC: H01H19/54
Filed: 2014-11-10
Abstract: Some systems require the use of two banks of batteries due to increased electrical power demand. A first bank of batteries may be used for a first task and a second bank of batteries may be used for a second task. A battery switch is required to control the banks of batteries. The battery switch is configured to control a first bank of batteries and a second bank of batteries, the first and second bank of batteries having at least one battery. The battery switch has a housing, a first bank terminal supported by the housing, a second bank terminal supported by the housing and connectable to the first bank terminal, a first load terminal supported by the housing and connectable to the first bank terminal, a second load terminal supported by the housing and connectable to the second bank terminal, and a selector supported by the housing and rotatably mounted to the housing. The selector has four positions including a first position in which the first and second bank terminals are disconnected from the first and second load terminals, a second position in which the first bank terminal is connected to the first load terminal and the second bank terminal is disconnected from the second load terminal such that no bank terminal is connected to the second load terminal, a third position in which the first bank terminal is connected to the first load terminal, the second bank terminal is connected to the second load terminal, and the first bank terminal is disconnected from the second bank terminal, and a fourth position in which the first bank terminal is connected to the first load terminal and the second bank terminal and the second bank terminal is connected to the second load terminal.
Patent NZ-732518-A (NZ)
Title: Fungicidal compositions
Inventor: MATHIESON TODD
IPC: A01N43/40
Filed: 2015-12-30
Abstract: Described herein is a method of controlling fungal plant pathogens or diseases comprising the steps of contacting the vegetation or an area adjacent thereto to prevent the growth of the fungal pathogens or diseases with a fungicidally effective amount of a fungicidal composition comprising: a) a fungicidal compound of the Formula; b) at least one ionic surfactant; c) at least one nonionic surfactant; d) from about 50 g/L to about 700 g/L of benzyl acetate; e) at least one N,N-dialkylcarboxamide; and f) from about 25 g/L to about 150 g/L of at least one organic solvent selected from the group consisting of: cyclohexanone, acetophenone, 2-heptanone, 2-heptanol, oleyl alcohol, and 2-ethylhexanol.
Patent NZ-735413-A (NZ)
Title: Cap for container
Inventor: MAGUIRE MICHAEL
IPC: B65D55/16
Filed: 2016-03-25
Abstract: The present invention relates to a cap for a container. The cap comprises a main body having a top plate and a circular sidewall, wherein one periphery of the circular sidewall connects to the top plate forming a closed end, and the other periphery of the circular sidewall at the opposite side of the closed end forms an opened end; and a ring member located at the opened end of the main body, separated from the main body by a first incision line, and connected to the main body by a plurality of connecting portions, wherein a plurality of second incision lines locate on the main body or the ring member and locate at one side of the plurality of connecting portions. The cap provided by the present invention will, while in its open and/or closed state, continue to be connected to its container.
Patent NZ-737775-A (NZ)
Title: An empty shotgun cartridge separating system
Inventor: LOUGHNANE STEPHEN
IPC: F42B33/06
Filed: 2016-05-09
Abstract: The present invention provides a system for separating empty or used ammunition cartridges, in particular spent plastic shotgun shells, in order to allow the plastic and metal component parts of the cartridge to be recycled. The empty shotgun cartridge separating system for separating a case from a head of the cartridge, the system comprising a restraint operable to engage the head; and a clamp operable to grip the case and draw the case out of register with the head, the restraint defining a guideway within which the head may be captured, the clamp being operable, while gripping the case, to displace the case relative to the restraint in order to displace the head along the guideway, the guideway diverging from the clamp in a direction in which the cartridge is conveyed by the clamp.
Patent NZ-740051-A (NZ)
Title: Tetracycline compounds
Inventor: XIAO XIAO-YI
IPC: C07D207/09
Filed: 2013-08-30
Abstract: The present invention relates to tetracycline antibiotic compounds having structural formula S4-14 or a pharmaceutically acceptable salt thereof, wherein R4 is selected from (methyl)(ethyl)amino, (methyl)(propyl)amino, (ethyl)(propyl)amino, (methyl)(isopropyl)amino and (ethyl)(isopropyl)amino. The present invention further relates to the use of these compounds for the manufacture of medicaments for the treatment of bacterial infections.
Patent NZ-741135-A (NZ)
Title: Design of synchronization signals for narrowband operation
Inventor: CHEN WANSHI
IPC: H04J11/00
Filed: 2016-08-26
Abstract: Aspects of the present disclosure provide techniques for design of synchronization signals for narrowband operation, which can be used for stand-alone/inband/ guard-band deployment. An example method is provided for operations which may be performed by a base station (BS). The example method generally includes generating a primary synchronization signal (PSS) utilizing a first code sequence and a cover code applied to the first code sequence over a first number of symbols within one or more subframes, generating a secondary synchronization signal (SSS) based on a second code sequence over a second number of symbols within one or more subframes, and transmitting the PSS and the SSS in the first and second subframes to a first type of a user equipment (UE) that communicates on one or more narrowband regions of wider system bandwidth.
Patent NZ-750426-A (NZ)
Title: Modified t lymphocytes having improved specificity
Inventor: ABBOT STEWART
IPC: A01N63/00
Filed: 2014-02-06
Abstract: Provided is the use of a modified T lymphocyte (CAR-T lymphocyte), which allows for tumour cell specific cytotoxicity, (in the manufacture of a medicament) for the treatment of cancer in a subject, the modified T lymphocyte comprising: a. a first polypeptide comprising a first extracellular antigen binding domain that binds a first antigen, and a first intracellular signaling domain that comprises an immunoreceptor tyrosine-based activation motif (ITAM), and wherein said first polypeptide does not comprise a co-stimulatory domain; and b. a second polypeptide comprising a second extracellular antigen binding domain binding a second antigen, or a receptor that binds said second antigen; and a second intracellular signaling domain that comprises one or more co-stimulatory domains but not an ITAM; or a. a first polypeptide comprising a first extracellular antigen binding domain that binds a first antigen, and a first intracellular signaling domain that comprises one or more co-stimulatory domains but not an immunoreceptor tyrosine-based activation motif (ITAM); and b. a second polypeptide comprising a second extracellular antigen binding domain binding a second antigen, or a receptor that binds said second antigen; and a second intracellular signaling domain, that comprises an ITAM, wherein said second polypeptide does not comprise a co-stimulatory domain; wherein: the first antigen is an antigen on a tumor cell, a tumor-associated antigen, or a tumor-specific antigen; the second antigen is vascular endothelial growth factor (VEGF) or a damage associated molecular pattern molecule (DAMP); and said modified lymphocyte becomes maximally cytotoxic only when said first signaling domain and said second signaling domain are both activated by said first antigen and said second antigen, respectively.
Patent NZ-762264-A (NZ)
Title: Waste processing system
Inventor: RIDDIFORD MARK
IPC: F23G5/20
Filed: 2018-08-30
Abstract: A disposal system and method of use for the processing of solid waste devices to recycle materials located within the devices and recover, reuse and recycle such materials. Such system may include a primary chamber and secondary chamber, attached preferably by use of one or more exhaust ducts, and a secondary chamber exhaust duct. The solid waste devices may include any type of waste, such as electronics waste, medical device waste, and the like. The waste disposal system having a heating chamber, a primary chamber disposed within the heating chamber, a secondary chamber, and lid. The method comprising loading feedstock into the primary chamber, heating the secondary chamber, heating the heating chamber with the feedstock inside, rotating the primary chamber while the primary chamber is being heated, cooling the heating chamber after the heating chamber is heated for a predetermined amount of time, and removing leftover concentrate after heating the heating chamber for the predetermined amount of time.
Patent NZ-768144-A (NZ)
Title: Spa structural support assembly
Inventor: NATHAN TULETT
IPC: E04H4/14
Filed: 2020-09-23
Abstract: A structural support system for a spa, the structural support system comprising: a plurality of vertical supports, at least one of the plurality of vertical supports (20) comprising a a first side and a second side. The support comprising a plurality of shaped openings (24) being open on the first side, and a plurality of shaped openings being open on the second side. The system further comprises at least one channel bracket (70), comprising a shaped boss (77) on a first side, a first groove (89) formed in a second side (86), and a second groove (89) formed in a third side (82), the third side being opposite the second side. The shaped boss is for interfacing with one of the plurality of shaped openings of the at least one of the plurality of vertical supports. The system further comprises at least one spa panel retention member (95), comprising a projection (104) to mate in the first groove of the channel bracket. The invention allows for quicker and easier access to operating components of a spa that are concealed behind the panels of a surrounding cabinet assembly.
Patent NZ-788488-A (NZ)
Title: Sensor device and system
Inventor: ANTAR DAVID
IPC: G08B17/12
Filed: 2019-05-28
Abstract: Embodiments of a sensor device, method and system employ a multiplicity of environmental sensors as a single monitoring and alerting mechanism, operable to provide a profile of any contaminant in terms of various gases and particles in the atmosphere, quantified in terms of relative concentrations. In various embodiments, the sensor device can comprise hardware and firmware elements, including an electronic control system, a case, a shield and a cover. The environmental sensors can be secured as part of the electronic control system and the shield can be formed so as to facilitate proper channeling of air and sound for effective operation.
Patent PT-101120-A (PT)
Inventor: MANO TAKASHI
IPC: C07C323/44
Filed: 1992-12-11
Abstract: Compounds of formula (I) wherein A is C1 to C3 alkylene, Ar is phenyl or styryl, R is halosubstituted C1 to C3 alkyl, NHR' or (II), R' is hydrogen or C2 to C8 alkylthioalkyl, n is an integer of from 1 to 4 and p is an integer of from 2 to 5, with the proviso that when R' is hydrogen then Ar is styryl, and the pharmaceutically acceptable salts thereof, inhibit the enzyme lipoxygenase and are useful in treating allergy and inflammatory and cardiovascular conditions for which the action of lipoxygenase has been implicated. These compounds form the active ingredient in pharmaceutical compositions for treating such conditions.