baber/WOPTO huggingface dataset:
Patent CA-2302282-A1 (CA)
Inventor: BURKE CARL
IPC: A61K47/42
Filed: 1998-09-01
Abstract: Compositions are provided for improving the stability of live virus vaccines containing, e.g., live varicella zoster, measles, mumps, and rubella viruses.  Such improved stabilizers are aqueous solutions containing recombinant human serum albumin (rHA) as a component at from 1-100 g/l. Live virus vaccines as well as methods of preparing live virus vaccines containing the stabilizers are also provided.
Patent CA-2303146-A1 (CA)
Title: Substituted 2-pyrrolidinone activators of pkc
Inventor: KOZIKOWSKI ALAN P
IPC: A61K31/4015
Filed: 1998-09-08
Abstract: Compounds of formula (I) wherein R1 and R2 are each independently (C1-C15)alkyl, (C2-C15)alkenyl, (C2-C15)alkynyl, (C3-C8)cycloalkyl, (C3-C8)cycloalkyl(C1-C10)alkyl, (C3-C8)cycloalkyl(C1-C15)alkenyl, (C3-C8)cycloalkyl(C1-C15)alkynyl, (C1-C15)alkoxy, (C1-C15)alkanoyl, (C1-C15)alkanoyloxy, aryl, heteroaryl, aryl(C1-C6)alkyl, heteroaryl(C1-C6)alkyl, aryl(C2-C15)alkenyl, heteroaryl(C2-C15)alkenyl, aryl(C2-C15)alkynyl, heteroaryl(C2-C15)alkynyl, aryl(C1-C15)alkoxy, heteroaryl(C1-C15)alkoxy, aryl(C1-C15)alkanoyl, heteroaryl(C1-C15)alkanoyl, aryl(C1-C15)alkanoyloxy, or heteroaryl(C1-C15)alkanoyloxy; wherein any R1 or R2 is optionally substituted with one or more substituents and their pharmaceutically acceptable salts, are PKC activators and are useful for treating diseases, such as, for example, cancer. Also disclosed are pharmaceutical compositions comprising compounds of formula (I), processes for preparing compounds of formula (I), and intermediates useful for preparing compounds of formula (I).
Patent CA-2303504-A1 (CA)
Inventor: KHANI-HANJANI ABBAS
IPC: G01N33/68
Filed: 2000-04-10
Abstract: In one aspect, the invention provides a method of diagnosis. The diagnostic method may include steps of identifying a patient at risk of an arthritis, the patient having an interferon gamma gene. The patient may be tested to characterize a polymorphism in a first intron of the interferon gamma gene.  The polymorphism may comprise a variable length dinucleotide repeat region within the first intron, and the dinucleotide repeat region may be located at least partly between nucleotides 1349 and 1373 in the interferon, gamma gene. The method may be carried out so as to be capable of identifying alleles such as the 126 by allele and the 122 bp allele, as further described herein. The polymorphisms may be distinguished based on a difference in the number of CA repeats in a portion of the first intron of the interferon gamma gene. The invention may also comprise testing a patient for a polymorphism is an HLA protein (or gene), such as the HLA-DRB 1 protein.
Patent CA-2303805-A1 (CA)
Inventor: CORNIL JEAN-PHILIPPE
IPC: G01N9/26
Filed: 1998-07-03
Abstract: The invention concerns a method for determining the density of a gas consisting in: filling a chamber (12) capable of sustaining the pressure without noticeable deformation with a gas whereof the density is to be determined and providing an initial pressure Pi higher than normal atmospheric pressure, by pressurised supply means (20); allowing said gas to escape through purging means (30) provided with a sonic nozzle (40), and measuring the time .DELTA.t taken by the gas to pass, inside the chamber (12), from a first pressure P1 not higher than the initial pressure Pi, to a second pressure P2 lower than said initial pressure P1; computing the density  of the gas being analysed using a general theoretical formula stored in a computer (60) memory and including said measured time .DELTA.t and the gas temperature T, and a constant k obtained by the calibrating computer calibration (60) on the basis of a reference gas whereof the density is known.
Patent CA-2307984-A1 (CA)
Title: Glider rocker lift chair
Inventor: CASEY KENNETH J
IPC: A61G5/14
Filed: 2000-05-09
Abstract: A chair comprises a base, a seat support frame which is longitudinally movable back and forth with respect to said base, and a seat. A lift mechanism mounts the seat on the frame and is capable of lifting said seat from a lowered seating position to a raised position to assist an occupant in exiting from the seat. Locking means is actuatable as the seat is raised to lock the frame against movement with respect to said base. The locking means is released as the seat is towered to its seating position to free the frame for movement with respect to said base.
Patent CA-2308178-A1 (CA)
Title: Process and apparatus for the production of virgin polymer substitutes
Inventor: BOWERS BRUCE O
IPC: C08J11/14
Filed: 1998-10-21
Abstract: The invention relates to processes and apparatus for the production of a virgin polymer substitute from cured scrap rubber, such as automobile tires, which does not involve the use of solvents or other chemicals and which substantially maintains the physical properties of the virgin material in the substitute. The process and apparatus may perform an initial analysis of the scrap material to be treated and determination of the process parameters for that particular material. Actual treatment of the material comprises grinding of the scrap rubber and preconditioning the ground material by subjecting it to warm dry air prior to subsequent treatment in a high temperature and pressure environment. The high temperature and pressure environment is created by means of a pressure vessel into which the preconditioned material is introduced, thereafter exposing the material to a variable high pressure and temperature environment which is controlled to optimize devulcanization of the material. Continuous agitation of the material during treatment serves to insure uniform heating and exposure of materials, thereby producing a substitute which can be used without substantial diminution in physical properties such as tensile and tear strength.
Patent CA-2308728-A1 (CA)
Inventor: OKUYAMA KODO
IPC: A61M16/12
Filed: 2000-05-05
Abstract: In a low-oxygen or hypoxic respiration system, the user breaths air stored in a substantially enclosed container, but an opening is provided in the mask or other part of the system so that a controlled amount of external air is introduced into the system. Therefore, as a result of the balance between the consumption of oxygen by the user and the replenishment of oxygen from the external air, the user can breath hypoxic or low-oxygen air for inhalation at the atmospheric pressure for an extended period of time. If desired, a carbon dioxide absorbing agent may be incorporated in the system so that an undesired increase in the concentration of carbon dioxide in the respiration air can be avoided.
Patent CA-2309021-A1 (CA)
Title: Device, method, and system for real-time couponing
Inventor: SHEN FRANCIS
IPC: H04L12/16
Filed: 2000-05-23
Abstract: A method, system, and a device, such as a web-enabled appliance, for providing electronic couponing to a user via a network, such as the Internet.  The coupon information is collected at a server on the network, referred to as the eCouponCard Site, by for example, transmission to the server from merchants or by the server periodically collecting coupon information from merchants. The device, which is connectable to the network by, for example, wire or cordless/wireless coupling, receives the coupon information from the server and transmits the information to a coupled smart card. The smart card is then taken to a merchant location for redemption of the coupon. At the merchant location, the coupon is redeemable electronically if the merchant has a smart card reader, or a redemption device is provided at the merchant location or elsewhere for printing a paper coupon for redemption. The redemption device is also capable of providing communication to the merchant or the server via, for example, a network to reconcile the redemption. The paper coupon optionally includes a bar code for reading by conventional bar code readers at the merchant location. In one variation, the server includes, or is coupled to one or more databases, and has a processor for storing information about the coupons, reconciling redemption information, providing information regarding redemption, and varying coupon and merchant information. For example, the server is capable of varying the value or availability of a coupon to adjust or otherwise balance supply and demand.
Patent CA-2310583-A1 (CA)
Title: Heater control
Inventor: CARL FREDERICK GORDEON JR
IPC: H05B1/02
Filed: 1998-11-04
Abstract: A method and apparatus are provided for controlling parallel heater elements (101, 102), the method including the steps of: providing a plurality of electrical heater elements; generating a plurality of temperature signals associated with a plurality of the heater elements; generating a control signal based on one or more temperature signals;  providing an alternating current power supply (103) connected to the electrical heater element through a power transmission system (111);  generating a signal when the voltage of the alternating current power supply passes through ground potential; blocking electrical power to a heater element starting when a zero detection signal is detected and ending when another zero detection signal is detected, for a fraction of the alternating current cycles in a time period, the fraction being a function of the control signal; and transmitting temperature control signals through the power transmission system.
Patent CA-2317908-A1 (CA)
Inventor: WILLIAMS BENJAMIN M
IPC: F41B11/62
Filed: 2000-09-07
Abstract: An adapter for converting self contained compressed gas-powered devices, designed for use with internally-housed standard disposable 12g. CO2 cartridges, to operation powered by larger sources of compressed gas. A specially designed and dimensioned gas delivery pipe fits within the cavity in the device normally occupied by a standard CO2 cartridge, and mates with the annular seal in the device that normally mates with the standard CO2 cartridge. A retaining plug engages a shoulder on the gas delivery pipe as well as the housing of the device to hold the gas delivery pipe in sealing engagement with the seal. The adapter has particular applicability to gas-powered guns, such as BB guns and paintball guns.
Patent CA-2319458-A1 (CA)
Title: Transabdominal examination, monitoring and imaging of tissue
Inventor: CHANCE BRITTON
IPC: A61B10/00
Filed: 1999-02-12
Abstract: An optical examination technique employs an optical system (15, 45, 100, 150, 200, 260 or 300) for in vivo, non-invasive examination of internal tissue of a subject. The optical system includes an optical module (12 or 14), a controller and a processor. The optical module is arranged for placement on the exterior of the abdomen or chest. The module includes an array of optical input ports and optical detection ports located in a selected geometrical pattern to provide a multiplicity of photon migration paths targeted to examine a selected tissue region, such as an internal organ or an in utero fetus. Each optical input port is constructed to introduce into the examined tissue visible or infrared light emitted from a light source. Each optical detection port is constructed to provide light from the tissue to a light detector. The controller is constructed and arranged to activate one or several light sources and light detectors so that the light detector detects light that has migrated over at least one of the photon migration paths. The processor receives signals corresponding to the detected light and forms at least one data set used for tissue examination.
Patent CA-2325615-A1 (CA)
Title: Method and apparatus for evaluating polynomials and rational functions
Inventor: ENENKEL ROBERT F
IPC: G06F17/11
Filed: 2000-11-10
Abstract: Disclosed herein are a computer-processing method and apparatus for computing values of polynomials or rational functions. A mathematical software library can advantageously embody the concepts of this invention. The method can be adapted to compute values for non-elementary,special functions, for example ERF, ERFC, LGAMMA, and Bessel functions. The steps for polynomial evaluation include presenting input data that includes coefficients of polynomial p(x), x, a predetermined x i, and p(x i), building polynomial c(x) having coefficients so that polynomial p(x) is expressible as: p(x) = p(xi) + {x - x i} . c(x), determining each coefficient of polynomial c(x), determining a value of polynomial c(x), and constructing a value of polynomial p(x) by determining: p(x) = p(x i) + {x - x i} . c(x). The method can be adapted for providing a value for a rational function r(x) = p(x)/q(x), which is a ratio of a numerator polynomial p(x) and a denominator polynomial q(x).
Patent CA-2330545-A1 (CA)
Inventor: RENZI PAOLO
IPC: A61K38/00
Filed: 1999-06-17
Abstract: The present invention relates to the use of antisense oligonucleotides directed against specific nucleic acid sequences coding for receptors, alone  or in combination, in order to inhibit the inflammatory reaction that is present in asthma, atopy or hypereosinophilia and to inhibit neoplastic cell  proliferation. The antisense oligonucleotides of the present invention are used for treating and/or preventing asthma, allergy, hypereosinophilia, general inflammation or cancer. The oligonucleotides of the present inventio n are more specifically directed against nucleic acid sequences coding for a CCR3 receptor, a common sub-unit of IL-4 and IL-13 receptors, or a common su b- unit of IL-3, IL-5 and GM-CSF receptors.
Patent CA-2332939-A1 (CA)
Title: Thermally conductive mounting arrangement for securing an integrated circuit package to a heat sink
Inventor: MOLLER THOMAS W
IPC: H01L23/433
Filed: 1999-05-12
Abstract: An electrical assembly includes an IC package having a thermally conductive mounting flange in contact with a heat sink. A thermally conductive casing i s secured to the heat sink, the casing at least partially enclosing the IC package. A resilient retaining member is disposed between the casing and IC package, the retaining member applying sufficent force on the IC package so as to maintain good thermal contact between the mounting flange and heat sink.< /SDOAB>
Patent CA-2333217-A1 (CA)
Inventor: HIURA HISAHIDE
IPC: G01N33/96
Filed: 2001-01-31
Abstract: A quality control material composition or a standard material for clinical laboratory tests, containing recombinant human serum albumin prepared by recombinant technology as a base component.
Patent CA-2334389-A1 (CA)
Title: Multi-colored aerated confectionery products and processes for making
Inventor: VAN LENGERICH BERNHARD
IPC: A23G3/54
Filed: 1999-05-25
Abstract: A process for making an aerated, confectionery product of multiple colors includes, as a first step, preparing a slurry of water, sugar, and gelatin. The slurry is divided into at least first and second portions or batches having a defined color to provide a second color. A dye or colorant of a color is added to the second portion or batch to provide a second color. Each of the first and second batches are then individually aerated to form first and second aerated streams of first and second colors of substantially identical density and rheological properties. After aeration of the first and second portions, the first and second colored streams are fed to an extrusion die manifold, where they are extruded in disproportionate amounts to form a multicolored a rope having the first and second colors of unequal proportion. A  starch anti-sticking agent is applied, and the rope is cut into individual pieces. The individual pieces are then dried to a 1 to % moisture content. The process may accommodate two, three, four or more different colors. Multicolored marbits (4-6/g) having disproportionate multiple colored phases can be prepared. The marbits can be consumed as novelty confections or can be added to ready-to-eat breakfast cereals.
Patent CA-2335988-A1 (CA)
Title: Machine a fabriquer des biscuits fourres
Inventor: VAN DER ENT JOHANNES G
IPC: A21C15/00
Filed: 1999-06-30
Abstract: L'invention concerne une machine (2) à fabriquer des biscuits fourrés, la machine recevant des moitiés (c) de biscuits à la sortie d'un four. Les moitiés (c) de biscuits sont ensuite alignées par un dispositif d'alignement (3) à servocommande. Les moitiés de biscuits sont transférées dans un premier montage à chaîne (12) qui transporte les moitiés de biscuits dans un dispositif de dépôt (34) dans lequel de la crème est déposée sur chaque moitié de biscuit. Puis les moitiés (c) de biscuits sont transférées dans un deuxième montage à chaîne (44) qui transporte les moitiés de biscuits dans une zone de recouvrement (52). Une série de grandes et petites pattes (50) pousse les moitiés de biscuits sans dépôt de crème. Une roue de recouvrement (56) possédant plusieurs pelles (60) espacées autour de la circonférence de la roue de recouvrement, soulève les moitiés de biscuits sans dépôt de crème du montage à chaîne. Les moitiés de biscuits sans dépôt de crème sont tournées et inversées. Les moitiés de biscuits sans dépôt de crème sont disposées au-dessus des moitiés de biscuits avec dépôt de crème jusqu'à ce qu'une grande patte (48) pousse la moitié de biscuit sans dépôt de crème sur une moitié de biscuit avec dépôt de crème pour former un biscuit fourré. Les biscuits fourrés sont ensuite transportés dans un dispositif de mise en stock (76) où ils sont triés et emballés.
Patent CA-2337081-A1 (CA)
Title: Resilient abrasive article with hard anti-loading size coating
Inventor: MINICK CHRIS A
IPC: B24D11/00
Filed: 1999-02-18
Abstract: A resilient abrasive article includes a resilient elongatable substrate, abrasive particles adhesively bonded to the substrate with a flexible make coat, and a hard size coat applied over the abrasive particles and flexible make coat. The size coat provides an anti-loading layer which is applied thinly enough to prevent the size coat from cracking and tearing the substrate during use.
Patent CA-2337481-A1 (CA)
Title: Cyclic compounds useful in the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions and preparation process
Inventor: GUERRIER DANIEL
IPC: C07D319/06
Filed: 1999-07-09
Abstract: The present invention relates to cyclic compounds which can be used in the treatment of dyslipidaemia, atherosclerosis and diabetes, to processes for preparing these compounds. The compounds of the invention correspond to formula (I) wherein the radicals X, Y, R, R1, R2, R3, R4, R5, R6, R7 have meanings as given in claim 1.
Patent CA-2337548-A1 (CA)
Title: Optical waveguide gratings device with adjustable optical spacing profile
Inventor: EGGLETON BENJAMIN JOHN
IPC: H04B10/29
Filed: 2001-02-19
Abstract: In accordance with the invention, an optical waveguide grating with an adjustable optical spacing profile comprises a waveguide grating in thermal contact with one or more resistive film coatings. A coating extends along the length of the grating and its local resistance varies along the length of the grating. In one embodiment, a plurality of overlaping coatings are chosen so the resistance variation of each is different, thereby permitting a variety of heat generation profiles to be effected by independent control of the coatings. The different heat generation profiles, in turn, proportionately change the grating geometric spacing and local refractive index along the grating length, providing the desired adjustable optical spacing profile.  Other embodiments use resistive films with abruptly changing or periodically changing heating variation.
Patent CA-2337876-A1 (CA)
Title: Gps signal fault isolation monitor
Inventor: BRENNER MATS A
IPC: G01S1/00
Filed: 1999-06-25
Abstract: A system to determine, from inertial reference apparatus and from GPS receiver apparatus, acceleration signals along a predetermined axis to determine the failure of a GPS satellite signal by comparison of the acceleration signals and to monitor newly acquired GPS satellite signals to determine if a satellite drift was present prior to acquisition.
Patent CA-2341805-A1 (CA)
Inventor: DUTTA SANDEEP
IPC: A61P25/06
Filed: 2001-03-23
Abstract: A new oral polymeric controlled release formulation suitable for the once-a- day administration of valproate compounds, such as divalproex sodium, has been discovered. This formulation exhibits significant advantages over the sustained release valproate formulations of the prior art. This formulation minimizes the variation between peak and trough plasma levels of valproate over a 24 hour dosing period. This formulation follows a zero-order release pattern thus producing essentially flat plasma levels of valproate, once steady-state levels have been achieved. This results in a significantly lower incidence of side effects for patients consuming such a formulation.
Patent CA-2343790-A1 (CA)
Inventor: CHANG PING WU
IPC: A23L33/20
Filed: 1999-09-10
Abstract: L'invention se rapporte à des compositions souples de graisse à teneur réduite en calories qui contiennent des mélanges de triglycérides comportant diverses combinaisons de restes d'acides aminés à chaînes longues mono-insaturées (C¿16? à C¿22?), longues saturées (C¿15? à C¿22?) et courtes (C¿2? à C¿4?). L'invention se rapporte également à l'utilisation de ces compositions dans des produits comestibles du type matières grasses donnant du croustillant et margarines.
Patent CA-2345082-A1 (CA)
Inventor: SAUNDERS JEFF A
IPC: A63F7/06
Filed: 1999-11-10
Abstract: Le torse de cette figurine jouet est pourvu d'au moins un bras pivotant associé à un mécanisme sollicité par ressort amenant le bras à effectuer un mouvement pivotant vers l'avant. Un ressort (78) est relié au bras et fournit la force d'impulsion. Le torse renferme des mécanismes de déclenchement et de verrouillage actionnés par un bouton poussoir (16) placé dans le dos de la figurine. Ce mécanisme comporte une tige d'arrêt et une came (65) entrant en prise et empêchant tout mouvement de retour lorsque le bras de la figurine est en l'air en position armée. L'énergie emmagasinée par le ressort est libérée par actionnement du bouton poussoir, ce qui permet au bras de pivoter rapidement vers l'avant.
Patent CA-2350666-A1 (CA)
Title: Mechanical transmission device for engine with variable volume displacement
Inventor: RABHI VIANNEY
IPC: F02B75/04
Filed: 1999-11-25
Abstract: A mechanical transmission device for an engine with variable volume displacement comprising a piston (2) interlocked in its lower part with a control rack (3), co-operating with a ball-bearing guiding device (4) and with a gear assembly (5) integral with a connecting rod (6) for transmitting movement between the piston and the connecting rod.