Patent SG-11201908183Y-A (SG)
Title: Skin barrier composition
Inventor: HAMMOND KEVIN
IPC: A61K31/7032
Filed: 2018-05-10
Abstract: 0- 5.5- 5.0- x (l c ) 4.0- 2 3.5- 3.0- - No Cream - N- Test cream (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 15 November 2018 (15.11.2018) WIPO I PCT omit VIII °nolo III olo 001 VIII Imo oimIE (10) International Publication Number WO 2018/206962 Al (51) International Patent Classification: A61K 47/10 (2017.01) A61K 31/191 (2006.01) A61K 9/06 (2006.01) A61K 31/7032 (2006.01) (21) International Application Number: PCT/GB2018/051262 (22) International Filing Date: 10 May 2018 (10.05.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1707489.9 10 May 2017 (10.05.2017) GB (71) Applicant: HYPHENS PHARMA PTE. LTD. [SG/SG]; 138 Joo Seng Road, 3rd Floor, 368361 (SG). (71) Applicant (for SC only): HASELTINE LAKE LLP [GB/GB]; Lincoln House, 5th Floor, 300 High Holborn, Greater London WC1V 7JH (GB). (72) Inventors: HAMMOND, Kevin; Alderside, 1 Porto Hey Road, Wirral Merseyside CH61 2XA (GB). DAVIS, Adri- an; 12 Limeway Terrace, Dorking Surrey RH4 1HZ (GB). (74) Agent: FINNIE, Isobel Lara; Haseltine Lake LLP, Lin- coln House, 5th Floor, 300 High Holborn, London Greater London WC1V 7JH (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (54) Title: SKIN BARRIER COMPOSITION W O 20 18/ 20696 2 Al 2.5 ............... O cp o cb o c p co o c. o 0 0 03 ts \ <0 Time post-application (minutes) Figure 2 (57) : The present invention provides a composition for topical administration of a polyhydroxy acid, such as lactobionate and especially zinc lactobionate, and low pH to an external body surface such as skin. The composition is designed to be highly effective in delivering low pH and zinc lactobionate across the layers of the skin to more effectively treat and prevent skin conditions involving a defective skin barrier such as eczema and severe dry skin. [Continued on next page] WO 2018/206962 Al MIDEDIMOMOIDEIRDERI001010110111110111011MEMOIS UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))