baber/WOPTO huggingface dataset:
Patent AU-2019213430-B2 (AU)
Title: Small molecule drug conjugates
Inventor: KRALL NIKOLAUS
IPC: A61K47/54
Filed: 2019-08-09
Granted: 2021-09-30
Abstract: Il:\szp\nterwov \NRPortbI\DCC\SZP\17131123 _.docx-1506/2018 
ABSTRACT 
A targeted therapeutic agent comprising a compound of formula (I): B-L-D, wherein: B is a 
low molecular weight binding moiety for Carbonic Anhydrase IX (CAIX); D is a drug moiety; 
and L is a linker group that undergoes cleavage in vivo for releasing said drug moiety in an 
active form. The drug moiety is suitably a cytotoxic agent for targeted delivery to cancer cells 
expressing CAIX. The binding moiety B suitably comprises a sulfonamidothiadiazole moiety.  
The binding moiety B may comprise one, two or more groups capable of binding to CAIX.  
The linker group suitably comprises a disulfide bond and/or a triazole group and/or a cleavable 
peptide group.
Patent AU-2019280075-B2 (AU)
Title: Detection of pathologies in ocular images
Inventor: VAN HEMERT JANO
IPC: A61B3/00
Filed: 2019-12-13
Granted: 2021-07-22
Abstract: 5 A computer-implemented method of searching for a region (410) indicative of a 
pathology in an image (400) of a portion of an eye acquired by an ocular imaging system 
(420), the method comprising: receiving (S10) image data defining the image; searching 
(S12) for the region in the image by processing the received image data using a learning 
algorithm; and in case a region in the image that is indicative of the pathology is found: 
10 determining (S14) a location of the region in the image; generating (S16) an instruction 
for an eye measurement apparatus to perform a measurement on the portion of the eye 
to generate measurement data, using a reference point based on the determined location 
for setting a location of the measurement on the portion of the eye; and receiving (S18) 
the measurement data from the eye measurement apparatus.  
15 
Fig. 3
3/10 
Start) 
Receive image data defining an image of a portion of an 10 Ieye 
Search for a region indicative of a pathology in the image 
by processing the received image data using a learning S12 
algorithm 
NO Has a region in the image 
that is indicative of the pathologyS1 
been found in the searching?S1 
YES 
Determine a location of the region in the image S14 
Generate an instruction for an eye measurement 
apparatus to perform a measurement on the portion of the 
eye to generate measurement data, using a reference 16 point based on the determined location for setting a 
location of the measurement on the portion of the eye 
|Receive the measurement data from the eye measurement 
apparatus S18 
End 
Figure 3
Patent AU-2019282671-B2 (AU)
Title: Transgenic animal for producing diversified antibodies that have the same light chain i
Inventor: LEIGHTON PHILIP A
IPC: C07K16/00
Filed: 2019-06-05
Granted: 2021-05-06
Abstract: This disclosure provides, among other things, strategies for minimizing antibody diversification in a transgenic animal that uses gene conversion for antibody diversification. In some embodiments, the animal may comprise a genome comprising an endogenous immunoglobulin light chain locus comprising: (a) a functional immunoglobulin light chain gene comprising a nucleic acid encoding a light chain variable region; and (b) a plurality of pseudogenes that are operably linked to the functional immunoglobulin light chain gene and that donate, by gene conversion, nucleotide sequence to the nucleic acid encoding a light chain variable region, wherein the pseudogenes are upstream or downstream of the functional immunoglobulin light chain gene and encode the same amino acid sequence as the light chain variable region of the functional immunoglobulin light chain gene of (a). In other embodiments, the locus may have a tandem array of coding sequences for the light chain.
Patent AU-2019283902-B2 (AU)
Title: Device for luminescent imaging
Inventor: YUAN DAJUN
IPC: G01N21/64
Filed: 2019-06-12
Granted: 2021-06-03
Abstract: A device includes a plurality of imaging pixels in a spatial pattern with a formation of features disposed over the pixels. A first and a second feature of the formation of features are disposed over a first pixel. A first luminophore is disposed within or over the first feature. A second luminophore is disposed within or over the second feature. A structured illumination source is to direct at least a portion of first photons in an illumination pattern to the first feature at a first time, and to direct at least a portion of second photons in the illumination pattern to the second feature at a second time. The structured illumination source includes an illumination pattern generator having an illumination pattern generator actuator connected to the illumination pattern generator to cause the illumination pattern to translate or rotate relative to the formation of features.
Patent AU-2019313480-B2 (AU)
Title: Systems and methods for maternal uterine activity detection
Inventor: MHAJNA MUHAMMAD
IPC: A61B5/364
Filed: 2019-08-01
Granted: 2022-06-16
Abstract: A method includes receiving bio-potential inputs; generating signal channels from the bio-potential inputs; pre-processing data in the signal channels; extracting R-wave peaks from the pre-processed data; removing artifacts and outliers from the R-wave peaks; generating R-wave signal channels based on the R-wave peaks in the pre-processed signal channels; selecting two or more of the R-wave signal channels; and combining the selected two or more R-wave signal channels to produce an electrical uterine monitoring signal.
Patent AU-2019360681-B2 (AU)
Title: Method and electronic device processing data
Inventor: KIM YOUNGWOOK
IPC: H04L47/36
Filed: 2019-10-16
Granted: 2020-12-10
Abstract: An electronic device including a communication circuit receiving data transmitted from another electronic device, a memory storing instructions, and at least one processor electrically connected to the communication circuit and the memory and including a control core and a plurality of operation cores. The at least one processor may execute the stored instructions to cause the control core to receive the data from the communication circuit, to classify the received data into data flows of a specified number depending on an attribute of the data, and to respectively allocate the data flows to the plurality of operation cores.
Patent AU-2020200854-B2 (AU)
Title: Anthelmintic depsipeptide compounds
Inventor: LE HIR DE FALLOIS LOIC
IPC: A01N43/72
Filed: 2020-02-06
Granted: 2021-08-05
Abstract: OF THE DISCLOSURE 
The present invention provides cyclic depsipeptide compounds of formula (I) and 
compositions comprising the compounds that are effective against parasites that harm animals, 
including humans. The compounds and compositions may be used for combating parasites in or 
on animals including mammals and birds. The invention also provides for an improved method 
for eradicating, controlling and preventing parasite infestation in animals, including birds and 
mammals.
Patent AU-2020201090-B2 (AU)
Title: Liquid pharmaceutical composition
Inventor: RINALDI GIANLUCA
IPC: A61K47/18
Filed: 2020-02-14
Granted: 2022-03-10
Abstract: The present invention relates to novel liquid pharmaceutical compositions of adalimumab, 
which include adalimumab or a biosimilar thereof, an histidine buffering agent such as 
histidine (or histidine buffer system such as histidine/imidiazolium-histidine), and a sugar 
5 stabiliser such as trehalose. Such a combination of components furnishes formulations 
having a stability (e.g. on storage and when exposed to stress) which is comparable to or an 
improvement upon those known in the art, and with fewer ingredients. Such advances will 
help adalimumab treatments to become more widely available at lower cost, and prolong the 
viability of pre-loaded delivery devices (e.g. pre-filled syringes) to reduce unnecessary waste 
0 of the drug.  
12073013_1 (GHMatters) P104495.AU.2
Patent AU-2020203688-B2 (AU)
Title: Hydroponics
Inventor: VAN BUUREN EUGENE
IPC: A01G31/06
Filed: 2020-06-04
Granted: 2022-06-16
Abstract: The invention relates to a planter (10) forming part of a hydroponic system. The 
planter (10) includes a longitudinal body (12) defining at least two longitudinally 
extending liquid channels (14.1, 14.2) and at least two plant holders (16, 18)defined in 
5 the body (12), the plant holders (16, 18) spaced on the outer circumference of the 
longitudinal body (12), each one of the at least two plant holders (16, 18) in fluid flow 
communication with one of the at least two longitudinally extending liquid channels 
(14.1, 14.2).  
Eden Green App - Hydroponics.DOCX
Patent AU-2020282612-B2 (AU)
Title: Underwater device for acquiring images of the bed of a body of water
Inventor: KANDUKURI RAJA
IPC: H02J7/00
Filed: 2020-05-12
Granted: 2023-09-07
Abstract: The invention relates to an underwater device for acquiring images of the bed of a body of water, comprising at least one sensor for detecting a sensor value, at least one electrical load, and an electrical power source for supplying the electrical load with electrical power. The underwater device is characterized in that, on the basis of the sensor value a determination is made whether a state of danger exists for the electrical load, and in that a power distribution unit is present, which separates the electrical load from the electrical power source if such a state of danger exists.
Patent AU-2020298768-B2 (AU)
Title: Secure payment transactions
Inventor: MARTINOVA ANTONINA IVANOVA
IPC: G06Q20/38
Filed: 2020-07-01
Granted: 2023-06-08
Abstract: A client comprising an application for secure payment transactions is provided. The application runs on a personal mobile communication device and the client accesses a service provided by a server, which includes a payment gateway. Various security measures are included in the client-server communication related to executing payment transactions in a secure environment.
Patent AU-2021200710-B2 (AU)
Title: Dynamic response prediction for improved bot task processing
Inventor: RON OFER
IPC: H04L51/04
Filed: 2021-02-04
Granted: 2022-02-17
Abstract: DYNAMIC RESPONSE PREDICTION 
FOR IMPROVED BOT TASK PROCESSING 
ABSTRACT 
Systems and methods can be provided for predicting responses during communication sessions 
with network devices. In some implementations, systems and methods can facilitate predicting 
responses using machine learning techniques. Messages received through a platform can be 
stored in a repository. A machine learning model may be trained using the stored messages.  
When a terminal device is communicating with a network device in a communication session, 
the messages exchanged in the communication session and the machine learning model can be 
used to predict future responses in real-time. The predicted future responses can be presented at 
the terminal device. A predicted response can be selected at the terminal device. Upon selection, 
the selected predicted response is transmitted to the network device during the communication 
session.  
56
Patent AU-2021201702-B2 (AU)
Title: Methods, systems and devices for pre-operatively planned glenoid placement guides and uses thereof
Inventor: WALCH GILLES
IPC: A61B17/17
Filed: 2021-03-17
Granted: 2022-04-14
Abstract: Methods, systems and devices for pre-operatively planned shoulder 
surgery guides and implants. Pre-operative planning methods for designing 
glenoid placement guides and depth-control pins based on considerations of 
multiple factors affecting the outcome of shoulder surgery. Methods of using 
surgery guides and implants, including glenoid placement guides and depth
control pins, in patients undergoing shoulder surgery.  
{H0559735.1} -47
11716720 _1 (GHMatters)P102940.AU.1
Patent AU-2021202894-B2 (AU)
Title: Aryl-or heteroaryl-substituted benzene compounds
Inventor: KUNTZ KEVIN WAYNE
IPC: C07D213/64
Filed: 2021-05-07
Granted: 2023-07-06
Abstract: The present invention relates to aryl- or heteroaryl -substituted benzene compounds.  
The present invention also relates to pharmaceutical compositions containing these 
compounds and methods of treating cancer by administering these compounds and 
pharmaceutical compositions to subjects in need thereof. The present invention also 
relates to the use of such compounds for research or other non-therapeutic 
purposes.
Patent AU-2021204343-B2 (AU)
Title: Intra-prediction method, and encoder and decoder using same
Inventor: PARK JOONYOUNG
IPC: H04N19/10
Filed: 2021-06-25
Granted: 2022-09-01
Abstract: A method for decoding an image, performed by a decoding apparatus, the method comprising: 
receiving prediction mode information; 
5 deriving an intra prediction mode for a current block based on the prediction mode information; 
and 
generating prediction samples of the current block based on the intra prediction mode, 
wherein the intra prediction mode is a horizontal prediction mode having a horizontal prediction 
direction, 
10 wherein the prediction samples are generated based on first reference samples located along the 
horizontal prediction direction with regard to locations of the prediction samples, 
wherein a prediction sample which is adjacent to a top boundary of the current block among the 
prediction samples is filtered based on a second reference sample located along a vertical direction with 
regard to a location of the prediction sample, 
15 wherein the second reference sample is adjacent to an upper side of the prediction sample, and 
wherein a filtering coefficient applied to a value of the prediction sample is larger than a filtering 
coefficient applied to a value of the second reference sample.  
20 
25
Patent JP-4738588-B2 (JP)
IPC: B01J29/70
Filed: 2000-11-16
Granted: 2011-08-03
Abstract: The present invention relates to a method for the removal of the templating agent from synthetic zeolites in general and in particular from silicalite, titanium silicalite and from composite materials containing zeolites and for their activation as catalysts. The method consists in treating the above materials with solvents in vapor phase and at a low temperature.
Patent JP-4588209-B2 (JP)
IPC: C07D233/52
Filed: 1998-09-23
Granted: 2010-11-24
Abstract: A compound selected from the group consisting of a compound of the formulawherein the substituents are defined as set forth in the specification and its salts with non-toxic pharmaceutically acceptable acids and bases useful for treating loss of bone matrix.
Patent JP-4271371-B2 (JP)
IPC: B01F13/00
Filed: 1999-01-05
Granted: 2009-06-03
Abstract: There is disclosed a method for analyzing a plurality of liquid samples, the method comprising: 
(a.) loading the liquid samples into a plurality of through-holes disposed in a platen; 
(b.) illuminating at least one through-hole with optical radiation; and 
(c.) analyzing the optical radiation emanating from the at least one through-hole.
Patent JP-4642227-B2 (JP)
IPC: B03C1/28
Filed: 1999-02-19
Granted: 2011-03-02
Abstract: A magnetic system and apparatus having a multi-dimensional gradient for continuous, on-line separation of components from a mixture of chemical entities which comprises at least one separation chamber with a plurality of channels and a plurality of magnets, and a method is provided for continuously and magnetically separating and treating components of a mixture of chemical entities using a multi-dimensional gradient.
Patent JP-4750273-B2 (JP)
IPC: G02C7/06
Filed: 1999-04-26
Granted: 2011-08-17
Abstract: A progressive ophthalmic lens element including a lens surface having an upper viewing zone having a surface to achieve a refracting power corresponding to distance vision, a lower viewing zone having a greater surface power than the upper viewing zone to achieve a refracting power corresponding to near vision, and an intermediate zon extending across the lens element having a surface power varying from that of the upper viewing zone to that of the lower viewing zone and including a corridor of relatively low surface astigmatism, the progressive ophthalmic lens element including progressive design elements selected to reduce myopia progression.
Patent JP-5165168-B2 (JP)
IPC: A61P31/04
Filed: 1999-09-22
Granted: 2013-03-21
Abstract: Pharmaceutical compositions are described comprising micronised colistin sulphomethate sodium. The micronised pharmaceutical may be used together with a carrier such as lactose. The pharmaceutical compositions may be packed into containers such as gelatin capsules and administered by powder inhalation.
Patent JP-4751986-B2 (JP)
IPC: H04J11/00
Filed: 2000-01-20
Granted: 2011-08-17
Abstract: A method is described for temporally aligning a received symbol that is transmitted via orthogonal channels, e.g., OFDM channels, with a reference symbol and/or an earlier received symbol. The method includes computing phases of the first symbol for the orthogonal transmission channels and comparing the computed phases of the first symbol with phases of the reference. The phases of the first symbol are successively displaced by a predetermined phase shift which depends on the channel frequency to obtain a correlation result. The temporal alignment is determined by detecting a correlation maximum based on the correlation result and used to synchronize the first symbol with the reference. The reference can also be an earlier received symbol to provide autocorrelation. The received symbols can be processed by applying a window function, e.g. a Hanning, Hamming or Blackman window. Phase correlation provides reliable time synchronization in the presence of jammers emitting narrowband signals in excess of 32 dB above the signal level.
Patent JP-4515641-B2 (JP)
IPC: H04M3/42
Filed: 2000-01-31
Granted: 2010-08-04
Abstract: The inventive method and system enable an increase in the amount of information that may be transmitted from a call-initiating first telecommunication terminal to an automated application or device or machine or the like in conjunction with the call request. The content of the A-number field to be transmitted from a conversion/transmission center to a destination second telecommunication terminal is modified by adding control information to the A-number field. This control information is used to control an actuating device that is connected to the second telecommunication terminal and which operates or forms a part of the automated application or device or machine.
Patent JP-4446111-B2 (JP)
IPC: F16D65/18
Filed: 2001-06-29
Granted: 2010-04-07
Abstract: PROBLEM TO BE SOLVED: To accurately control braking force without depending on settings of a current reference value or a reference position of a motor and using a special sensor component. SOLUTION: In the dynamo-electric brake device, the braking force is generated by transmitting rotation of the motor 12 to a piston 11 via a ball ramp mechanism 13, advancing the piston 11, and pressing a pair of brake pads 3 and 4 against a disc rotor D. The piston 11 is formed from a sintered body of a ceramic pressure sensitive element having a piezoresistance effect of an internal resistance changing when a pressure is applied. A pair of electrode 21 is buried in a portion easily causing distortion of the piston 11. A change in resistance of the piston 11 occurring when the brake pads 3 and 4 are pressed against the disc rotor D is fetched via the electrodes 21 and a cable line 22.  The motor 12 is controlled on the basis of a precedently stored correlation between braking force and a value of resistance so that desired braking force is provided, namely, so that a target value of resistance is provided.
Patent JP-5138851-B2 (JP)
IPC: C12N9/50
Filed: 2000-06-27
Granted: 2013-02-06
Abstract: Methods for the production of purified, catalytically active, recombinant memapsin 2 have been developed. The substrate and subsite specificity of the catalytically active enzyme have been determined. The substrate and subsite specificity information was used to design substrate analogs of the natural memapsin 2 substrate that can inhibit the function of memapsin 2. The substrate analogs are based on peptide sequences, shown to be related to the natural peptide substrates for memapsin 2. The substrate analogs contain at least one analog of an amide bond which is not capable of being cleaved by memapsin 2. Processes for the synthesis of two substrate analogues including isosteres at the sites of the critical amino acid residues were developed and the substrate analogues, OMR99-1 and OM99-2, were synthesized. OM99-2 is based on an octapeptide Glu-Val-Asn-Leu-Ala-Ala-Glu-Phe (SEQ ID NO:28) with the Leu-Ala peptide bond substituted by a transition-state isostere hydroxyethylene group (FIG. 1). The inhibition constant of OM99-2 is 1.6×10−9 M against recombinant pro-memapsin 2. Crystallography of memapsin 2 bond to this inhibitor was used to determine the three dimensional structure of the protein, as well as the importance of the various residues in binding. This information can be used by those skilled in the art to design new inhibitors, using commercially available software programs and techniques familiar to those in organic chemistry and enzymology, to design new inhibitors to memapsin 2, useful in diagnostics and for the treatment and/or prevention of Alzheimer's disease.
Patent JP-4384832-B2 (JP)
IPC: E21D9/12
Filed: 2000-06-28
Granted: 2009-12-16
Abstract: A process of boring a tunnel using an earth-pressure balance shield boring tunnelling machine having a cutting head, an excavation chamber for soil removed by boring and conveying means for removal of said soil from the excavation chamber; wherein there is injected into a stratum being bored at the cutting head a foamed aqueous solution, characterized in that (a) the aqueous solution contains two essential components which are (i) a sulphate- or sulphonate-containing anionic susfactant, and (ii) beta-naphthalene sulphonate-formaldehyde condensate; and in that (b) there is applied to the soil removed by boring in at least one of the excavation chamber and the conveyor a second aqueous solution containing essentially a high molecular weight polyethylene oxide and optionally a sulphate- or sulphonate-containing anionic surfactant. The process allows easy removal of soil from the cutting head to the excavation chamber and from the excavation chamber out of the machine. It is particularly effective for sticky soils with high proportions of clay and high water content.
Patent JP-3757166-B2 (JP)
IPC: F25B9/00
Filed: 2000-08-03
Granted: 2006-03-22
Abstract: A method of forming a heat exchanger apparatus on a housing wall. The heat exchanger includes inner and outer annular rings. The rings have heat radiating, high surface area fins attached on oppositely facing surfaces. The inner ring has a radially outwardly facing surface that abuts the interior surface of the housing sidewall. The outer ring has a radially inwardly facing surface that abuts the exterior surface of the housing sidewall. When displaced longitudinally along the ring axes, which are coincidental, the sidewall is clampingly engaged therebetween, and an excellent thermal flow path is formed. Heat transferred into the inner fins from a working gas is conducted to the inner ring, through the sidewall, into the outer ring, then into the outer fins. Air impinging upon the outer fins absorbs the heat from the outer fins.
Patent JP-3848573-B2 (JP)
IPC: G06F21/60
Filed: 2000-12-14
Granted: 2006-11-22
Abstract: A microcontroller for security applications includes an encryption unit between a bus and a functional unit. The encryption unit includes a gate and a key register. A memory is provided with a further encryption unit whose gate is connected between the register and the gate of the first encryption unit. As a result, the transferred information item is available in encrypted form at any point on the bus.