baber/WOPTO huggingface dataset:
Patent EP-0988059-B8 (EP)
Inventor: BURKE PHILIP JOHN
IPC: A61K47/48
Filed: 1998-06-15
Granted: 2006-03-01
Abstract: A compound having formula I for use in medicine and, in particular, for the treatment of mammalian tumours. <??>A compound comprising a target cell-specific portion and human NAD(P)H:quinone reductase 2 (NQO2) or a variant or fragment or fusion or derivative thereof which has substantially the same activity as NQO2 towards a given prodrug, or a polynucleotide encoding said NQO2 or said variant or fragment or fusion or derivative. <??>A recombinant polynucleotide comprising a target cell-specific promoter operably linked to a polynucleotide encoding human NAD(P)H:quinone reductase 2 (NQO2) or a variant or fragment or fusion or derivative thereof which has substantially the same activity as NQO2 towards a given prodrug. <??>The compounds and polynucleotides are useful in a method of treating a patient in conjunction with a suitable prodrug. <IMAGE>
Patent BR-PI0515935-B8 (BR)
Title: pirimidinas heterociclil- ou 5-carbo substituídas para inibição de hiv, e composição farmacêutica
Inventor: JAN HEERES
IPC: C07D409/12
Filed: 2005-09-29
Abstract: pirimidinas heterociclil- ou 5-carbo substituídas para inibição de hiv. inibidores de replicação de hiv da fórmula (i), n-óxidos, sais de adição farmaceuticamente aceitáveis, aminas quaternárias ou formas estereoisoméricas dos mesmos, em que: - a1 = a2 - a3 = a4 é -ch=ch=ch=ch-, -n=ch-ch=ch, -n=ch-n=ch-, -n=ch-ch=n, -n=n-ch=ch; -b1 = b2 - b3 = b4 é -ch=ch-ch=ch, -n=ch-ch=ch, -n=ch-n=ch, -n=ch-ch=n-, -n=n-ch=ch, -n=ch-ch=ch, -n=ch-n=ch, -n=ch-ch=n-, -n=n-ch=ch-; r1 é hidrogênio; arila; formila; c1-c6 alquila opcionalmente substituída; c1-c6 alquilóxicarbonila; r2 é oh; halo; c2-c6 alquinila opcionalmente substituída; carbonila substituída; carboxila; cn; nitro; amino; amino substituído; polihalometila; polihlometiltio; -s(=o)rr6; c(=nh)r6; r2a é cn;amino; amino substituído; c1-c6 alquila opcionalmente substituída; halo; c1-6 alquilóxi opcionalmente substituído carbonila substituída; -ch=n-nh-c(=o)-r16; c1-6 alquilóxi c1-6 alquila opcionalmente substituída; c2-6 alquenila ou c2-6 alquinila opcionalmente substituída; -c(=n-o-r8)-c1-4 alquila; r7 ou -x3-r7; x1 é -nr1 -, -o-, -c(=))-, ch2, -choh-, s-, -s(=o)-; r3 é cn; amino; c1-c6 alquila; halo; c1-c6 alquilóxi opcionalmente substituido; carbonila substituída; -ch=n-nh-c(=o)-r16; c1-c6 alquila substituída;c2-c6 alquenila ou c2-c6 alquinila opcionalmente substituída; -c(=n-o-r8)-c1-4 alquila; r7; -x3-r7; r4 é halo; oh; c1-6 alquila opcionalmente substituída; c2-6 alquenila ou c2-6 alquinila; c3-7 cicloalquila; c1-6 alquilóxi; cn; nitro; polihalo c1-6 alquila; polihalo c1-6 alquilóxi; carbonila substituída; formila; amino; mono- ou di(c1-4 alquil)amino ou r7; r5 é -y-cqh2q-l ou cqh2q-y-c2h2r-l; l é arila ou het; processos para o preparo desses compostos, composições farmacêuticas compreendendo esses compostos como ingredientes ativo e o uso desses compostos para a prevenção ou tratamento de infecção pelo hiv.
Patent BR-PI0518957-B8 (BR)
Title: Módulo de bateria secundária
Inventor: JIN WOONG HA
IPC: H01M50/211
Filed: 2005-12-06
Abstract: PROCESSO PARA PREPARAÇÃO DE MÓDULO DE BATERIA SECUNDÁRIA E MÓDULO DE BATERIA SECUNDARIA. Trata-se de um processo para preparação de um módulo de bateria secundária. O processo inclui formar orifícios atravessadores de acoplamento que têm conformações específicas nos terminais de eletrodo em forma de chapa de uma série de pilhas unitárias, empilhar as pilhas unitárias umas sobre as outras e inserir elementos de acoplamento através dos orifícios atravessadores de acoplamento de modo a acoplar as pilhas unitária umas com as outras. Consequentemente, são obtidos o acoplamento seguro e a conexão elétrica entre as pilhas unitárias sem o uso de elementos adicionais, tais como cartuchos e, portanto, é preparado um módulo de bateria compacto com alta força de acoplamento.
Patent BR-PI0704082-B8 (BR)
Inventor: JENNY G DU
IPC: A61F13/511
Filed: 2007-10-30
Abstract: A cover material for an absorbent article including a fibrous nonwoven substrate, the substrate having a tortuousity value in the range of about 0.8 to about 3.0, and a particulate skin care material including a particulate material having a particle size in the range of about 1 micron to about 75 microns.
Patent BR-PI0711968-B8 (BR)
Inventor: DOUGLAS IVAN JENNINGS
IPC: A61M5/32
Filed: 2007-05-29
Abstract: An injection device 110 is described having a housing 112 and a cap 130. The injection device 110 houses a syringe 114 having a needle which is sealed by a boot 118. The cap 130 is arranged so that the boot 118 can be connected to the cap 130 while exerting a minimal force on the syringe, but cannot be removed from the cap 130 without applying a significantly greater force to the syringe. The housing 112 and cap 130 are arranged so that upon removal of the cap 130 from the housing 112, the boot 118 is removed from the syringe 114.
Patent BR-PI0821687-B8 (BR)
Title: método e dispositivo para a determinação da pressão transmembrana e aparelho para o tratamento sanguíneo extracorpóreo.
Inventor: ALFRED GAGEL
IPC: A61M1/34
Filed: 2008-12-17
Abstract: método e dispositivo para a determinação de uma pressão transmembrana em um tratamento sanguíneo extracorpóreo. a presente invenção refere-se a um método para a determinação da pressão transmembrana durante um tratamento sanguíneo extracorpóreo no qual o sangue flui a uma vazão de sangue definida através de um conduto de sangue arterial 6 de um circuito de sangue extracorpóreo 5a para a entrada de uma primeira câmara 3 de um dialisador 1, o qual é dividido por uma membrana semipermeável 2 na primeira câmara e em uma segunda câmara 4, e flui através de um conduto de sangue venoso 7 a partir da saída da primeira câmara 3 do dialisador 1, enquanto o líquido de diálise flui através de um conduto de suprimento de líquido de diálise 10 para a entrada da segunda câmara do dialisador e flui através de um conduto de descarga de líquido de diálise 11 a partir da saída da segunda câmara do dialisador. o método de acordo com a invenção e o dispositivo de acordo com a invenção para a determinação da pressão transmembrana são tais que a pressão no lado de sangue e no lado de líquido de diálise do dialisador é medida com um gasto técnico relativamente pequeno, especificamente com menos do que quatro sensores de pressão 20, 21, 22 e um valor não-corrigido preliminar é calculado para a pressão transmembrana e, após isso, é corrigido por uma variável de correção que é dependente de uma variável de correlação com a viscosidade do sangue.
Patent BR-PI0922911-B8 (BR)
Title: unidade de cilindro de gás
Inventor: CARLOS AGUIAR
IPC: B65D25/24
Filed: 2009-12-16
Abstract: unidade de cilindro de gás é divulgada uma unidade de cilindro de gás comprimido que inclui um corpo metálico do cilindro tendo uma porção de extremidade superior com alças e uma válvula de controle de fluxo, e uma porção de extremidade inferior com uma superfície convexa da qual depende um anel de suporte inferior. um colar anular não condutor circunda o anel de suporte inferior do corpo do cilindro, e um anel de base condutor conecta o colar anular ao anel de suporte inferior do corpo do cilindro, oferecendo um caminho condutor à terra para o corpo metálico do cilindro.
Patent BR-112012000643-B8 (BR)
Title: método e dispositivo para articulação do quadril
Inventor: FORSELL PETER
IPC: A61F2/34
Filed: 2010-07-12
Abstract: método e dispositivo para articulação do quadril 1. dispositivo médico para a implantação em uma articulação do quadril de um paciente humano é fornecido. a articulação do quadril natural com um caput de fêmur em forma de bola como a parte proximal do osso femoral com uma superfície convexa articulação de quadril para o centro da articulação do quadril e um acetábulo em forma de bacia como parte do osso pélvico com uma superfície côncava de articulação de quadril para o centro da articulação do quadril. o caput de fêmur tem uma extensão longitudinal posicionado no centro, estendendo-se pelo centro do caput e do colo do fêmur, alinhado com o colo do fêmur definido como eixo central do caput e do colo do fêmur. o dispositivo médico caracterizado por compreender um acetábulo artificial, que compreende uma superfície côncava em direção ao centro da articulação do quadril. o acetábulo côncavo artificial é adaptado para, quando implantado, ser fixado ao osso femoral do paciente humano, e estar em conexão móvel com um caput de fêmur artificial fixado ao osso pélvico do paciente.
Patent BR-112012021451-B8 (BR)
Title: uso de células que apresentam uma eficiência desejada para a expressão e/ou secreção dos fatores pró-angiogênicos vegf, cxcl5 e il8, métodos para construir um banco de células, para desenvolver fármaco, e para aumentar a expressão de um ou mais fatores pró-angiogênicos em uma célula realizado in vitro, e, composição
Inventor: ANTHONY E TING
IPC: A61K35/545
Filed: 2011-02-23
Abstract: uso de células que apresentam uma eficiência desejada para a expressão e/ou secreção de um ou mais fatores pró-angiogênicos, métodos para construir um banco de células, para desenvolver fármaco, e para aumentar a expressão de um ou mais fatores pró-angiogênicos em uma célula realizado in vitro, composição, e, células. a invenção fornece métodos para tratar condições patológicas que podem ser melhoradas fornecendo angiogênese. a invenção diz respeito em geral ao fornecimento de angiogênese administrando células que expressam e/ou secretam um ou mais fatores pró-angiogênicos. a invenção também diz respeito aos métodos de desenvolvimento de droga para selecionar agentes que modulam a capacidade das células para expressar e/ou secretar um ou mais fatores pró-angiogênicos. a invenção também diz respeito aos bancos de células que podem ser usados para fornecer células para a administração a um indivíduo, os bancos compreendendo células com níveis desejados de expressão e/ou secreção de um ou mais fatores pró- angiogênicos.
Patent EP-1194194-B9 (EP)
Inventor: CZINTOS CSONGOR
IPC: E01C13/10
Filed: 2000-06-21
Granted: 2006-03-08
Abstract: A downhill sliding course of sliding track for sliding objects and persons down a slope or a hill includes covering or cladding elements for covering the surface of the slope and a water source to moisten the elements with water. The sliding elements include pools located one below the other, wherein the pools are forming water filled micro-terraces (10). The micro-terraces (10) are formed by a sheet covering the slope in a water-tight manner and flexible ribs (2) are emerging from the sheet, furthermore each pool is bordered by the covering sheet (5) and the rib (2) and is closed by a flexible transverse sectioning rib joined to the covering sheet (5) and the flexible rib (2). With suitable accessories activities similar to skiing, sleighing and surfing can be performed on the sliding course. Accordingly, the invention includes also accessories that can be used to perform these activities. The invention provides individual appliances to implement the sliding course.
Patent EP-1342336-B9 (EP)
Inventor: KIM YOUNGLOK
IPC: H04B1/707
Filed: 2001-12-05
Granted: 2006-09-06
Abstract: The present invention is a system and method for transmitting data symbols in a CDMA communication system including a transmitter having an antenna array and a receiver. The system generates a first and second data field of symbols, then encodes them to produce complex conjugates of the respective symbols. A first communication burst including the first and second data fields, which are separated by a midamble, over a first antenna, and a second communication burst produced using said complex conjugates of said first and second data fields, which are separated by a midamble, over a second antenna are then transmitted by the transmitter. The receiver then receives and decodes the first and second communication bursts to recover the first and second data fields.
Patent EP-1953859-B9 (EP)
Inventor: KATO CHISATO
IPC: H01M8/24
Filed: 2006-10-18
Granted: 2012-05-16
Abstract: セパレータ（５０）とセパレータ（４０）とによって、断熱部材（６０）が挟持されている。断熱部材（６０）は、発電セル（２００）の温度低下を防止する断熱層として機能する。セパレータ（４０）の表面の溝と分離板（３０）とによって囲まれる空間に不純物除去流路（４２）が形成され、また、セパレータ（２０）の表面の溝と分離板（３０）とによって囲まれる空間に不純物除去流路（２２）が形成される。不純物除去流路（２２），（４２）は、反応ガスに含まれる不純物を除去するフィルタとして機能する。ターミナル（１０）は、発電セル（２００）で発生した電気を集電する集電層として機能する。このように、端部積層体（１００）は、発電セル（２００）の温度低下を防止する断熱層、反応ガスに含まれる不純物を除去する不純物除去層、発電セル（２００）で発生した電気を収集する集電層として機能する。
Patent EP-1093202-B9 (EP)
Inventor: KLINGBEIL THOMAS
IPC: G01V3/06
Filed: 1999-10-15
Granted: 2006-06-28
Abstract: Procedure detects earthed conductors (6) in a contact free manner by injection of a voltage into the earth conductor of the drill and measurement of the voltage at the drill point which is isolated from the rest of the drill. Alternately if the drill does not have an earth conductor then a measurement signal is injected into the earth conductor of the power supply network.
Patent AU-2000250048-B9 (AU)
Title: Inhalation therapy decongestant with foraminous carrier
Inventor: ROLF DAVID
IPC: A61K9/70
Filed: 2000-05-12
Granted: 2006-10-12
Abstract: A vaporizable decongestant is supported and stabilized on a flexible foraminous carrier composed typically of open-cell plastic foam, cloth or other fibrous material such as nonwoven fabric. The term "foraminous" herein is intended to refer to a substance or medium containing minute openings or perforated by many minute apertures. The decongestant is placed on the surfaces within the interstices and minute apertures or on fibers from which the foraminous carrier is formed. Vaporization of the inhalable decongestant is facilitated by providing the potential for greatly increasing its exposed surface area. Distributing the decongestant composition over the large, expanded surface within the foraminous carrier is beneficial in enhancing both the volatilization and evaporation of the decongestant agent. It also prolongs the useful life of the product. Once vaporized, the aromatic decongestant is available for natural inhalation through the nose or mouth to help relieve one or more of the symptoms of cough, colds, nasal or chest congestion and related symptoms. The foraminous carrier is preferably provided in the form of a patch or sheet that is bonded to the skin to serve as a supporting base for the active decongestant agent. The patch defining the carrier is typically adhesively bonded to the upper part of the body, <i>e.g.</i> on the face, neck or chest, in a location where the decongestant is liberated into the air and can be inhaled through the mouth or nose.
Patent AU-2016300170-B9 (AU)
Title: Cleaning method, apparatus and use
Inventor: BIRD ROBERT ANDREW
IPC: D06F35/00
Filed: 2016-07-28
Granted: 2020-12-17
Abstract: A method for cleaning a substrate which is or comprises a textile, the method comprising agitating the substrate and a cleaning composition comprising: • i. cleaning particles comprising a thermoplastic polyamide and a hydrophilic material at least part of which is located inside the cleaning particle, said cleaning particles having an average particle size of from 1 to 100 mm; and • ii. a liquid medium. An apparatus suitable for performing said method comprising a rotatable cleaning chamber and a particle storage tank containing the cleaning particles. Use of the cleaning particles for cleaning a substrate which is or comprises a textile.
Patent AU-2016420664-B9 (AU)
Title: Service establishment method and device
Inventor: CHONG WEIWEI
IPC: H04W72/12
Filed: 2016-08-23
Granted: 2020-06-11
Abstract: The present application relates to the technical field of communications, and disclosed in the embodiments thereof are a service establishment method and device, used to solve the problem wherein a service cannot be executed normally due to forced allocation of a wireless resource to a UE after a service establishment request is received. The specific solution is: an access network device receiving a first establishment request; sending a first establishment response to a first core network device or a first service application server, the first establishment response being used to instruct the access network device to accept the first establishment request; when wireless channel quality of a first cell of a first network where a UE is located does not meet a service requirement of a first service carried in the first establishment request, sending a first notification message to the first core network device or the first service application server, or switching the UE to a second cell of a first network, or switching the UE to a third cell of a second network, the first notification message being used to indicate that the wireless channel quality of the first cell does not meet the service requirement of the first service. The present application is used in a service establishment process.
Patent DE-102016108311-B9 (DE)
Title: Verfahren zur Herstellung einer Kabelzugentlastung und Steckverbinder mit dieser Kabelzugentlastung
Inventor: GRIMM MICHAEL
IPC: H01R13/58
Filed: 2016-05-04
Granted: 2017-12-07
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung einer Kabelzugentlastung eines an einem Steckverbinder anzubringenden Kabels mit rundem Querschnitt mit einem Kabelmantel mit einem Außenumfang U1 mit den folgenden Schritten: Bereitstellen eines metallischen Ringelementes aus einer ringförmigen Wand mit einem im Wesentlichen kreisförmigen Querschnitt, wobei das Ringelement einen Innenumfang U2 aufweist, der größer ist als der Außenumfang U1 des Kabelmantels; Aufbringen des Ringelements auf den Kabelmantel des Kabels an einer definierten Position; Verformen des Ringelementes derart, dass der durch die Verformung erzeugte reduzierte Innenumfang U3 kleiner oder gleich dem Außenumfang U1 des Kabelmantels ist, so dass es am Kabelmantel fixiert ist und die Wand des Ringelements ferner in wenigstens einem Bereich zur Reduzierung des ursprünglichen Innenumfangs U2 so umgeformt ist, dass wenigstens ein aus der Wand gebildeter und umgeformter Ringelementabschnitt radial nach Außen gegenüber dem Kabelmantel hervorsteht und wobei das umgeformte Ringelement von einem runden Querschnitt in einen polygonalen Querschnitt verformt ist.
Patent BR-0313575-C1 (BR)
Inventor: WEST SIMON MICHAEL
IPC: A61K47/34
Filed: 2003-08-07
Abstract: There is provided a method for improving the efficacy and/or transdermal transport of topically administered pharmaceuticals and pharmacologically active compounds, said method comprising the step of incorporating the pharmaceutical or pharmacologically active compound in a carrier comprising an effective amount of one or more complexes of a phosphate derivative of a lipophilic pharmaceutically acceptable compound.
Patent DE-3421908-C1 (DE)
Title: Apparatus for producing holes in laminar material
Inventor: ALT GERHARD DIPL-ING
IPC: B24B27/06
Filed: 1984-06-13
Granted: 1985-08-14
Abstract: The apparatus comprises two clamping plates (1, 2), which can be pressed together, which clamp the web (3) of material between them in their closing plane and in which there is at least one pair of bores (5, 6) which are aligned with one another and which are at least as large as the holes (4) to be produced in the web (3) of material, of a grinding tool, which has a rotating grinding body (7) of the same diameter as the holes (4) to be produced in the web (3) of material, is axially adjustable in the bores (5, 6) and is provided on its front end (19) with a grinding surface (10) which has sharp edges at least around its periphery, and of a counter-holder (11), which projects into the bore (6) up to the closing plane of the two clamping plates (1, 2) in such a manner as to be displaceable under the force of a spring (12) and can be restored by the grinding body (7) against the force of the spring (12). A spike (13), which projects coaxially towards the counter-holder (11), is provided on the end (19) of the grinding body (7) facing the counter-holder (11), and a recess (14) to accommodate the spike (13) is arranged in the counter-holder (11). The spike (13) fixes the thin slice to be ground out of the web (3) of material while clamped between the grinding body (7) and the counter-holder (11) until it has been completely separated from the web of material. <IMAGE>
Patent DE-3440199-C1 (DE)
Title: Solder contact promoter
Inventor: GRILL GUENTER
IPC: B23K35/00
Filed: 1984-11-03
Granted: 1986-04-03
Abstract: The invention relates to a solder contact promoter for pretreating solder points in solder joints between alloy parts, in particular dental-alloy parts. In order to be able to make corrosion-resistant and adhesive solder joints between the alloy parts, the invention proposes applying to the solder point elemental palladium or a palladium compound which is preferably provided as a palladium powder suspension or dissolved or suspended in a solvent. The elemental palladium sinters together through exposure to heat and diffuses into the surface of the solder point of the alloy part. If the solder contact promoter contains a palladium compound, elemental palladium, which also sinters together and diffuses into the surface of the solder point of the alloy part, is released by thermal dissociation after exposure to heat. Very fine dental-alloy parts can consequently be soldered together. Anionic surfactants and/or nonionic surfactants, alkali fluorides and lithium compounds, as optional components, improve the action of the solder contact promoter.
Patent DE-3441155-C1 (DE)
Title: Preparation of polyacrylic acid, and the use thereof as padding agent
Inventor: PROBST JOACHIM DR
IPC: C08F2/16
Filed: 1984-11-10
Granted: 1986-06-12
Abstract: Thermally stable, light-stable polyacrylic acids and their salts which are obtainable by polymerisation of acrylic acid in aqueous solution in the presence of aliphatic azo compounds as initiators are used as padding agents in the dyeing of polyester and cellulose.
Patent DE-3442334-C1 (DE)
Inventor: GAIGL KARL-JOSEF
IPC: B23Q16/02
Filed: 1984-11-20
Granted: 1986-05-22
Abstract: A device for the stepped driving of an axle-shaft (23) or similar, in a rotational direction around an axle (A), in which the axle-shaft (23) is equipped with at least one engagement element that travels along a cam system. The engagement element is designed as a rotary bar (17) and engages in a cam opening (15) of a slide plate (6) that moves in a plane roughly perpendicular to the axle (A).
Patent DE-3545215-C1 (DE)
Inventor: HAGENS HAJO
IPC: G01K1/12
Filed: 1985-12-20
Granted: 1986-11-06
Abstract: 1. Device for recording measured values on a permanent-heating furnace carriage with a temperature protective container in which a battery operated measured value storage circuit is arranged to which a plurality of measurement sensors are connected which are arranged on the permanent-heating furnace carriage outside the temperature protective container, characterised in that arranged in the temperature protective container (2 to 7) there is a starter circuit (16) which, when a voltage is applied to its control input, switches on the measured value storage circuit (13) and that connected to the control input is a control line (19, 22) whose ends (23) are external on the permanent-heating furnace carriage (1).