baber/WOPTO huggingface dataset:
Patent DE-69125374-D1 (DE)
Title: Endonukleasen
Inventor: JENNINGS PHILIP
IPC: C12N9/00
Filed: 1991-06-17
Granted: 1997-04-30
Abstract: This invention provides catalytic molecules capable of cleaving target nucleotide sequences. More specifically, the invention provides an endonuclease having nucleotide sequences which are of sufficient length to allow hybridisation to a target nucleotide sequence desired to be cleaved. The endonuclease contains a catalytic region comprising ribonucleotides and/or deoxyribonucleotides, or derivatives thereof which act to cleave a phosphodiester bond of the substrate nucleotide sequence. The catalytic region comprises nucleotides or derivatives thereof which are linked by linking groups which may comprise ribonucleotides, deoxyribonucleotides or combinations thereof. The endonucleases of the invention are useful in the cleavage of target RNAs associated with disease in humans and animals and in the inactivation of RNA transcripts in eukaryotic and prokaryotic cells, as well as the cleavage of RNA transcripts in-vitro.
Patent DE-69129912-D1 (DE)
Inventor: SPANGLER MICHAEL
IPC: B65G15/02
Filed: 1991-11-28
Granted: 1998-09-03
Abstract: A spiral conveyor system utilising an endless flat belt (12) is disclosed. The belt (12) travels in an endless path which includes a spiral portion. The belt (12) is primarily driven in the spiral portion by a frictional engagement between the belt (12) and a rotating driving element (26). The frictional engagement is enhanced by attaching friction increasing elements (40) to the belt (12) and/or driving element (26). <IMAGE>   <IMAGE>
Patent DE-69203153-D1 (DE)
Inventor: VARI SANDOR GEORGE VAN
IPC: A61B18/20
Filed: 1992-04-02
Granted: 1995-08-03
Abstract: A method and apparatus is disclosed for the instant intraoperative detection and biopsy of metastatic cancer using fluorescence spectroscopy. A photosensitizing agent selectively retained by cancerous tissue is administered prior to surgery. A fiberoptic probe (1) integrated with a biopsy device (2) illuminates the examined tissue and causes fluorescence which is recorded by a spectrograph and plotted as a spectral curve. The intensity ratio (S1/S2) for the fluorescence from the photosensitizing agent (S1) and autofluorescence (S2) for the examined tissue is compared with the intensity ratio at the same wavelengths for primary tumor and normal tissue. Tissue that displays an intensity ratio different from that of normal tissue can immediately be analyzed for the depth of tumor involvement and then excised for histological examination using the biopsy device. <IMAGE>
Patent DE-69203939-D1 (DE)
Inventor: RENARD PIERRE
IPC: C07C15/02
Filed: 1992-05-04
Granted: 1995-09-14
Abstract: A process is described for production of aromatic hydrocarbons from a charge of aliphatic hydrocarbons containing 2 to 12 carbon atoms, in an enclosure 1 comprising a plurality of pipes 3 which are filled with a catalyst and which are parallel and arranged in rows. A stage called reaction stage and a regeneration stage of the catalyst in the pipes of the enclosure are carried out. Heating of the pipes is produced by suitable radiant heating means 6, situated between two successive rows and arranged in sheets which are substantially perpendicular to the pipes. These sheets heat a first part of the pipes (feed side) with a heat flow greater than the mean heat flow of the heating means and a subsequent second part with a mean flow no greater than the mean heat flow, so that the isothermal condition (isothermicity) of the catalyst is substantially maintained, by virtue of suitable control means. Application to the production of benzene, toluene and xylenes. <IMAGE>
Patent DE-69207458-D1 (DE)
Inventor: JAEPOELAE JARI
IPC: F16K31/60
Filed: 1992-02-27
Granted: 1996-02-22
Abstract: The invention concerns a valve stem adjustment device suitable for setting the valve handle to a predetermined height from the wall surface irrespective of the valve recessing depth in the wall. The device is comprised of an extension shaft (4) fitted between the stem (2) of the valve (1) and the valve handle (3) and of a protective bushing (5) enclosing the extension shaft. The extension shaft (4) can be trimmed steplessly according to installation instructions so that the handle (3) of the valve (1) remains at a predetermined height from the wall surface when mounted to the end of the extension shaft. <IMAGE>
Patent DE-69216746-D1 (DE)
Inventor: HAMMOND MILTON L
IPC: C07K7/54
Filed: 1992-10-01
Granted: 1997-02-27
Abstract: Certain propanolamine compounds which have a cyclohexapeptidyl nucleus and which are found to have extremely active antibiotic activity with physical properties suitable for direct use in therapeutic compositions are described. A novel process for their preparation is also described.
Patent DE-69217533-D1 (DE)
Inventor: WEEBER WILLIAM BERNARD
IPC: H04J3/06
Filed: 1992-10-02
Granted: 1997-03-27
Abstract: A SONET pointer interpretation in system which an Alarm Indication Signal (AIS) of a first type is interpreted as a subset of Loss of Pointer (LOP) of a first type. Specific events are defined for entering an AIS type 1 state and for exiting this state. Specific events are also defined for entering an LOP type 1 state and for exiting this state. Finally, a truth table is defined for mapping these states into a valid pointer (NORM) state, an AIS of a second type state and an LOP of a second type state. <IMAGE>   <IMAGE>
Patent DE-69221278-D1 (DE)
Inventor: KATSUMATA TOHRU
IPC: C08G18/56
Filed: 1992-12-23
Granted: 1997-09-04
Abstract: A polyacetal resin composition capable of providing a molding having a remarkably lowered surface gloss, while maintaining the mechanical properties and moldability inherent in polyacetal, comprises:   (A) 100 parts by weight of a polyacetal resin and, incorporated therein, (B) 1 to 50 parts by weight of a polyalkylene terephthalate copolymer having a melt flow temperature of 210 DEG C or below, and (C) 0.1 to 10 parts by weight of an isocyanate or isothiocyanate compound, or a modification thereof. b
Patent DE-69233667-D1 (DE)
Inventor: DOMENIGHINI MARIO
IPC: A61K38/00
Filed: 1992-12-30
Granted: 2007-01-11
Abstract: An immunogenic detoxified protein comprising the amino acid sequence of subunit A of cholera toxin (CT-A) or subunit A of an Escherichia coli heat labile toxin (LT-A) or a fragment thereof wherein one or more amino acids at, or in positions corresponding to Val-53, Ser-63, Val-97, Tyr-104 or Pro-106 are replaced with another amino acid or deleted. Examples of specific replacements include Val-53-Asp, Val-53-Glu, Val-53-Tyr, Ser-63-Lys, Val-97-Lys, Val-97-Tyr, Tyr-104-Lys, Tyr-104-Asp, Tyr-104-Ser, Pro-106-Ser. The immunogenic detoxified protein is useful as vaccine for Vibrio cholerae or an enterotoxigenic strain of Escherichia coli and is produced by recombinant DNA means by site-directed mutagenesis. <IMAGE>
Patent DE-69301494-D1 (DE)
Inventor: CUGNON DE SEVRICOURT MICHEL
IPC: A61K31/165
Filed: 1993-04-01
Granted: 1996-03-21
Abstract: Compounds useful in therapeutics of formula: <IMAGE> in which R2 and R3 represent, independently of one another, H, C1-C4 alkoxy or OH and (A, B) = (oxygen, oxygen), in which case either R or R1 represents OH, halogen, secondary amino or tertiary amino and the other represents NHNHCONHR4 or else R and R1 together form =N-NH-CX-NHR5, =N-NH-CX-N(phenyl)2, =N-NH-CX-NH-NH-R5, =N-NH-C(SCH3)=N-R6 or =N-N=C(SCH3)-NH-R6, or (A, B) = (N-OH, oxygen), in which case R and R1 together form =N-NH-CX-NHR5 or =N-NH-CX-N(phenyl)2, or (A, B) = (N-NH-CX-NHR5, oxygen), in which case R and R1 together form =N-NH-CX-NHR5, or (A, B) = (N-OH, N-OH), in which case R and R1 together form =N-NH-CX-NHR5 or =N-NH-CX-N(phenyl)2.
Patent DE-69310563-D1 (DE)
Inventor: TAKADA SUSUMU
IPC: C07D471/04
Filed: 1993-02-08
Granted: 1997-06-19
Abstract: A compound of the formula: <CHEM> wherein R is an optionally substituted aryl group or an optionally substituted aromatic heterocycle group; ring A is a 5 to 9 membered alicyclic group, in which one or more carbon atoms constituting said ring A may be replaced by O, S, SO, SO2 and/or NR<1> (in which R<1> means hydrogen, alkyl, esterified carboxy group, carbamoyl or an acyl group) and/or said ring A may have an alkyl group as a substituent or its salt. The compounds of the present invention are useful as psychotropic agents such as antianxiety agents, anaesthesia antagonistic agents or cerebral function activators.
Patent DE-69315468-D1 (DE)
Inventor: MURAKAMI KEIICHI
IPC: B41J2/16
Filed: 1993-04-15
Granted: 1998-01-15
Abstract: An ink jet recording head comprising energy generating elements for applying the heat energy to the ink, heat acting portions for forming bubbles in the ink with said energy generating elements, a heat storing layer having insulating property for storing the heat energy disposed adjacent to said energy generating elements, and a support substrate for supporting said heat storing layer, characterized in that said support substrate is composed mainly of metal, and said heat storing layer is a chemical conversion coating which is formed through chemical treatment of the surface of said substrate. <IMAGE>
Patent DE-69315808-D1 (DE)
Inventor: MARTIN CHRISTOPHER
IPC: A61B17/04
Filed: 1993-10-14
Granted: 1998-01-29
Abstract: A suture securing device (1) and method for intracorporeally securing a suture includes a surgically implantable body (2) having a tissue abutting side (5) and a suture loop side (4), and a passage (3) through the body having an opening (6) adjacent the tissue abutting side and another opening (7) adjacent the suture loop side. When a loop of suture is positioned through the passage from the tissue abutting side (5) and emerges from the suture loop side, and a free portion of suture is passed through the loop, the loop clamps upon the free portion when the loop is retraced back into the passage.
Patent DE-69315977-D1 (DE)
Inventor: AUTEN RICHARD D
IPC: G02C7/02
Filed: 1993-11-01
Granted: 1998-02-05
Abstract: Tinting comprises: (a) providing an unhydrated contact lens; (b) providing a dyestuff soln.; (c) providing a printing block comprising a hydrophilic polymer material contg. a dye complexing agent capable of non-covalently bonding the dyestuff; (d) placing the dyestuff soln. onto the printing block; (e) contacting the unhydrated contact lens and the printing block for a time sufficient to allow the dyestuff soln. to diffuse to the lens; and (f) removing the lens from the printing block.
Patent DE-69318411-D1 (DE)
Inventor: WOOD LOUIS
IPC: C08G69/10
Filed: 1993-08-05
Granted: 1998-06-10
Abstract: Solutions of polymers of aspartic acid or its amine copolymers prepared by thermal condensation are reacted with a decolorizing agent selected from the group consisting of hypochlorfte, chlorine, chlorine dioxide, hydrogen peroxide, a peroxycarboxylate or ozone, sufficient in strength to effect the desired decolorization.
Patent DE-69323033-D1 (DE)
Inventor: RATANA KANLUEN RATANA KANLUEN
IPC: C11D1/22
Filed: 1993-10-26
Granted: 1999-02-25
Abstract: Non-chlorinated, low alkalinity, high retention liquid hard surface cleaner concentrate and use solutions containing amine oxide surfactant, an anionic surfactant, a hydrophobically modified polymer surfactant, a thinner, and alkali are provided, which form viscous solutions upon dilution and which in cleaning operations, are capable of producing gel-like foams. The composition synergistically exhibits exceptional cleaning performance without the need of chlorine or high levels of caustic.
Patent DE-69326451-D1 (DE)
Inventor: CHERPECK RICHARD
IPC: C10L1/30
Filed: 1993-12-20
Granted: 1999-10-21
Abstract: A fuel additive composition comprising:   (a) A fuel-soluble aliphatic amine selected from the group consisting of (1) a straight or branched chain hydrocarbyl-substituted amine, (2) a hydroxyalkyl substituted amine, and (3) a straight or branched chain hydrocarbyl-substituted succinimide; and (b) a polyalkyl hydroxyaromatic compound or salt thereof wherein the polyalkyl group has sufficient molecular weight and carbon chain length to render the polyalkyl hydroxyaromatic compound soluble in hydrocarbons boiling in the gasoline or diesel range.
Patent DE-69330178-D1 (DE)
Inventor: STAVENHAGEN DR
IPC: A61B17/70
Filed: 1993-12-13
Granted: 2001-05-31
Abstract: The present invention relates to a device for setting a spline having damaged vertebras, comprising an anchoring element including a shaft portion (16) to be attached to spaced vertebras, the free end of said anchoring element including a slot (24) for receiving a distracting or, respectively, compressing bar (40), and a cap nut (42) to be screwed onto an outer thread (32) provided in the region of the receiving slot to urge an axial fixing portion (44) towards the bar received in said receiving slot. The invention is defined in that the receiving slot (24) is formed in a separate swiwel head (20) including an inner end in the shape of a ball receiving portion (24) which has an aperture (28) through which said shaft portion (16;52) of the anchoring element (10;50) extends, wherein the diameter of the shaft portion adjacent said aperture is smaller than that of said aperture (28), and that a ball head (14;56) is provided at the end of the shaft portion (16;52), said ball head having a diameter larger than that of said aperture (28) and said ball head (14;56) in the ball receiving portion (24) entering the terminal region of said receiving slot (24). <IMAGE>
Patent DE-69330340-D1 (DE)
Inventor: NAGAO HIROMASA
IPC: C12N9/54
Filed: 1993-03-17
Granted: 2001-07-19
Abstract: A modified protease is disclosed, which is a mutant of the thermostable neutral protease wherein at least one amino acid residue of SEQ ID NO: 1 selected from the group consisting of the 144th leucine residue, the 150th aspartic acid residue, the 187th glutamic acid residue and the 227th asparagine residues is replaced with an amino acid residue other than said amino acid.
Patent DE-69332200-D1 (DE)
Inventor: LORCH D
IPC: C07K1/14
Filed: 1993-04-05
Granted: 2002-09-19
Abstract: Methods for isolating EG III cellulase component and enriched EG III cellulase in polyethylene glycol are disclosed. The methods comprise adding an inorganic salt and polyethylene glycol having a molecular weight of from about 5,000 to 10,000 to an aqueous mixture of cellulase proteins under conditions to create a two-phase system. Next, the cellulase proteins other than EG III are separated in an EG III-poor aqueous phase while EG III cellulase component is retained in an EG III-rich polyethylene glycol phase. Lastly, the EG III component can be separated from the polyethylene glycol. The preferred method of separation is alcohol precipitation.
Patent DE-69334348-D1 (DE)
Inventor: CHU CHUNG K
IPC: C07D473/34
Filed: 1993-08-25
Granted: 2011-03-31
Abstract: A method and composition for the treatment of humans infected with HIV that includes administration of an HIV treatment amount of an enantiomerically pure  beta -D-dioxolanyl purine nucleoside of formula (I), wherein R is OH, Cl, NH2, or H, or a pharmaceutically acceptable salt or derivative of the compound, optionally in a pharmaceutically acceptable carrier or diluent.  <CHEM>   <IMAGE> <IMAGE>
Patent DE-69401252-D1 (DE)
Inventor: RANTANEN KARI
IPC: H01R13/629
Filed: 1994-03-28
Granted: 1997-02-06
Abstract: The invention relates to an extension plug-in unit comprising a socket (2) connected to a first cable (1) and a plug (4) connected to a second cable (3), said plug (4) and socket (2) having cooperating contact means (5, 6) comprising male and female contacts for electrical connection of the first cable (1) to the second cable (3) and cooperating connecting means (7, 8, 9) for joining the plug (4) mechanically to the socket (2). To enable a mechanically simple and reliable construction, the male and female contacts (5, 6) are disposed to be located substantially in succession in the axial direction of the cables (1, 3), and the mechanical contact means comprise hinge means (7 8) at one end of the plug and the socket for articulated joining of the plug and socket and locking means (9) at the other end of the plug and the socket for locking the plug (4) and socket (2) together at said ends when they are pressed against one another.
Patent DE-69403060-D1 (DE)
Inventor: FORINO LUCIANO
IPC: A61M39/16
Filed: 1994-01-10
Granted: 1997-06-12
Abstract: A flexible envelope for protecting medical appliances against contamination, particularly as when used for the administration, draining or withdrawal of substances, comprising: a highly impermeable and strong flexible backing sheet (11); a layer of padding (12) made of a highly absorbent flexible spongy material which entirely covers one side of said backing sheet (11) and is attached to it by a weld line (at 13), e.g. by hot welding or electrical welding; a flexible nonwoven covering (14) attached to and covering said layer of padding (12) by a weld line (at 15), for example by hot welding or electrical welding, providing a three-layer sandwich pad (16), the peripheral edges of which are turned over on to the free side (14.1) of said covering (14) and are sewn with a seam (17) so as to form a continuous hem (16.1) in relief; and furthermore comprising mutually adhesive but separable sealing means (18.1, 18.2; 23.1, 23.2) which, when said flexible envelope (10, 20) is closed upon itself by being folded along a predetermined fold line (16.3, 21) adhere separably one on top of the other and close said envelope.
Patent DE-69407029-D1 (DE)
Inventor: AYRES GEORGE EDWARD
IPC: A24F13/18
Filed: 1994-01-10
Granted: 1998-01-08
Abstract: A cigarette extinguishing and storage device is of tubular shape and provided by telescoping elements which define an enclosure in which a lit cigarette is received to extinguish the same and in which the extinguished cigarette is stored until the smoker wishes to relight the same. Charcoal or other suitable deodorant means is provided at the internal surface of the enclosure to absorb condensates from tobacco smoke. The device preferably is made of one or more plies of paper, so as to be disposable.
Patent DE-69408668-D1 (DE)
Inventor: CHAPDELAINE MARC
IPC: A61P25/00
Filed: 1994-06-09
Granted: 1998-04-02
Abstract: Antagonists at the NMDA receptor complex which are benz[b]azepines having a hydroxy, alkoxy or amino substituent at the 3-position and a 4-position alkenyl, alkynyl, aryl or heteroaryl substituent for treatment of stroke and/or other neurodegenerative disorders.
Patent DE-69408822-D1 (DE)
Inventor: PARIS JEAN
IPC: A43B5/04
Filed: 1994-11-14
Granted: 1998-04-09
Abstract: The boot has a shell (1) and a leg (2) with a back part (3) and a cuff (4). A front part (5) closes the upper front opening (6) in the leg and is articulated (14) near the tip of the shell, while its upper edge (5') engages under the lower edge (13') of the cuff. The cuff has feet (11) which are articulated on an axle (12) on vertical wings (7) on the shell, above the skier's ankle (17) and opposite the joint (8) between the front cap and the cuff. The front part is slightly flexible and has clips (10) on either side which deform it elastically.
Patent DE-69413708-D1 (DE)
Inventor: HUMBERSTONE VICTOR CAREY
IPC: B05B17/00
Filed: 1994-12-08
Granted: 1998-11-05
Abstract: A method of and apparatus for atomising a liquid are disclosed, in which a liquid is caused to pass through tapered perforations (50) in a vibrating membrane (5) in the direction from that side of the membrane (5) at which the perforations (50) have a smaller cross-sectional area to that side of the membrane (5) at which the perforations (50) have a larger cross-sectional area.
Patent DE-69414618-D1 (DE)
Inventor: SOLLARS JOHN ALEXANDER JR
IPC: D03D25/00
Filed: 1994-02-01
Granted: 1998-12-24
Abstract: Air bag comprises an inflatable fabric woven with interconnected right and left hand 2 x 1 twill lines extending diagonally for forming diamond shaped areas of plain or other type weave and with some areas of the fabric having smaller diamond areas and the diamond areas having some floated warp yarns over the filling yarns and across the syntehtic continuous filament yarns e.g. of polyester, nylon, etc.
Patent DE-69419631-D1 (DE)
Inventor: NISHIO JIRO
IPC: B27N3/24
Filed: 1994-02-17
Granted: 1999-09-02
Abstract: A process capable of improving dimensional stability and surface properties of a lignocellulosic material is disclosed which comprises holding a lignocellulosic material (W) between hot platens (1a,1b) in a sealed condition, and heating the lignocellulosic material to vaporize moisture contained in the lignocellulosic material per se; thereby effecting high-pressure steam (V) treatment of the lignocellulosic material. In the treatment, the lignocellulosic material may be maintained in a compressed condition, or an external high-pressure steam (V) may be supplied from the surfaces of the hot platens toward the lignocellulosic material. <IMAGE>
Patent DE-69427542-D1 (DE)
Inventor: TING C
IPC: A61K31/451
Filed: 1994-12-05
Granted: 2001-07-26
Abstract: Disclosed are compounds of Formula I:    <IMAGE>  (I)  or a pharmaceutically acceptable salt or solvate thereof. Also disclosed are pharmaceutical compositions containing compounds of Formula I, methods for inhibiting tumor necrosis factor- alpha  and methods for treating septic shock, inflammation, or allergic disease.
Patent DE-69507598-D1 (DE)
Inventor: VERRELST WIM
IPC: C10G50/00
Filed: 1995-02-22
Granted: 1999-03-11
Abstract: PCT No. PCT/EP95/00667 Sec. 371 Date Oct. 22, 1996 Sec. 102(e) Date Oct. 22, 1996 PCT Filed Feb. 22, 1995 PCT Pub. No. WO95/22516 PCT Pub. Date Aug. 24, 1995Oligomerization degree of olefins may be controlled by employing mixed molecular sieve catalysts. Propene may be trimerized to nonene using ZSM-5 and ZSM-22, especially in an extrudate admixture.
Patent DE-69514100-D1 (DE)
Inventor: HU HONG
IPC: C07C235/54
Filed: 1995-03-15
Granted: 2000-01-27
Abstract: Compounds having the formula   <IMAGE>   methods for using such compounds to inhibit protein kinase C in animals, including man are useful as inhibitors of protein kinase C. Also disclosed are pharmaceutical compositions including such compounds and compounds having the formula.
Patent DE-69515293-D1 (DE)
Inventor: ROSENGREN LARS
IPC: F21V5/02
Filed: 1995-03-14
Granted: 2000-04-06
Abstract: The present invention is for a lighting device by which a controlled light pattern is obtained from a specific light source. The device comprises a light source which emits several parallel light beams. There is one prism (3) for each light beam (8), which passes through the lighting device. All of the prisms are integrated parts of a common disc. Preferrably the light source comprises several light emitting diodes (1) each emitting one light beam. The prisms are suitably made as straight, circular cylinders, at least those parts thereof which protrude from the common disc. The oblique surface may be freely varied at both its angle at the axis of the cylinder and direction whereby the direction of the corresponding light beam may be controlled.
Patent DE-69519681-D1 (DE)
Inventor: HENDERSON WILLIAM
IPC: A61K31/295
Filed: 1995-08-25
Granted: 2001-01-25
Abstract: PCT No. PCT/EP95/03367 Sec. 371 Date Jun. 16, 1997 Sec. 102(e) Date Jun. 16, 1997 PCT Filed Aug. 25, 1995 PCT Pub. No. WO96/05816 PCT Pub. Date Feb. 29, 1996This invention relates to methods of treating or controlling a disease or stress condition such as laminitis in a non-human mammal by topically applying to the limb of the mammal a nitrovasodilator and a protective covering dressing in the form of a cuff, sleeve, or boot.