baber/WOPTO huggingface dataset:
Patent AU-2012318896-B2 (AU)
Title: Pyrrolopyrimidine compounds for the treatment of cancer
Inventor: WANG XIAODONG
IPC: C07D471/04
Filed: 2012-10-01
Granted: 2017-03-02
Abstract: The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemia (ALL) cells and a potential cause of ALL chemoresistance. Hence, we investigated whether the development of small molecule Mer inhibitors was possible. A first aspect of the present invention is a compound (sometimes referred to as an "active compound" herein) of Formula I, IA, or IB.
Patent AU-2012323287-B2 (AU)
Title: A method for purifying antibodies
Inventor: BERNETT MATTHEW J
IPC: C07K16/00
Filed: 2012-10-10
Granted: 2018-02-01
Abstract: The invention relates generally to compositions and methods for purifying the desired species from a mixture of desired heterodimer and contaminating homodimer immunoglobulin variants by modifying the isoelectric point(s) of the individual chains.
Patent AU-2012325253-B2 (AU)
Title: Cartridge, method for producing said cartridge, and multi-component cartridge
Inventor: ETTLIN JOSEF
IPC: B05C21/00
Filed: 2012-08-20
Granted: 2016-11-17
Abstract: The invention relates to a cartridge, comprising at least one receiving chamber (2) extending in the longitudinal direction for a medium to be discharged, an end side (4) and a cartridge wall (3), which delimit the receiving chamber (2) and are injection-molded as one piece, wherein the end side (4) comprises an outlet for the medium and the cartridge wall (3) comprises a first film (6) on the inner side thereof, delimiting the receiving chamber (2), said first film extending over the entire cartridge wall (3) and being non-detachably joined to the cartridge wall (3). The invention further relates to a method for producing such a cartridge and to a multi-component cartridge.
Patent AU-2012331447-B2 (AU)
Title: Optically variable security element
Inventor: BAHR ANNETT
IPC: B42D15/00
Filed: 2012-11-05
Granted: 2016-08-04
Abstract: The invention relates to an optically variable security element (12) for security papers, value documents and other data carriers, with a substantially transparent carrier (20) having opposing first and second main surfaces (22, 24), an arrangement of micro-lenses (26) on the first main surface (22) of the carrier (20), and a laser-sensitive recording layer (32) arranged on the second main surface of the carrier (20). According to the invention, the micro-lens arrangement (26) is furnished with a laser-sensitive cover layer (28) having at least one cut-out (30) produced by the effect of laser radiation and extending over several micro-lenses (26), the laser-sensitive recording layer (32) comprises a plurality (34) of micro-markings (36) produced by the effect of laser radiation, wherein each micro-marking (36) is associated with one micro-lens (26) and is visible through the associated micro-lens (26) during inspection of the security element (12), and the plurality (34) of micro-markings (36) on the carrier (20) is arranged precisely aligned directly opposite the at least one cut-out (30).
Patent AU-2012338629-B2 (AU)
Title: Process for increasing hydrogen content of synthesis gas
Inventor: ABBOTT PETER EDWARD JAMES
IPC: C01B3/16
Filed: 2012-10-10
Granted: 2016-03-10
Abstract: A process is described for increasing the hydrogen content of a synthesis gas containing one or more sulphur compounds, said synthesis gas comprising hydrogen, carbon oxides and steam, and having a ratio, R, defined as R = (H
Patent AU-2013201643-B2 (AU)
Title: Anti-malarial pharmaceutical composition
Inventor: BOOLES CLIVE
IPC: A61K31/357
Filed: 2013-03-19
Granted: 2015-02-12
Abstract: The invention provides pharmaceutical compositions for the treatment and prophylaxis of malaria, comprising artemether and a medium chain triglyceride formulated for transmucosal sublingual, buccal or nasal delivery, especially by a spray. Also provided are delivery devices containing the compositions.
Patent AU-2013209315-B2 (AU)
Title: Display apparatus and image control method thereof
Inventor: YANG CHENG-CHUNG
IPC: G09G3/32
Filed: 2013-07-24
Granted: 2015-05-07
Abstract: A display apparatus includes a display panel and a driving module. The driving module is electrically connected with the display panel and has an image processing circuit and a data driving circuit. The image processing circuit receives a first image signal of a frame time. When an average gray level of the first image signal is greater than or equal to a first setting gray level, the image processing circuit reduces gray levels of the first image signal according to a first ratio to obtain a second image signal. The data driving circuit receives the second image signal and drives the display panel to display an image according to the second image signal. An image control method of the display panel is also disclosed. 1600 ------- --- ------ -- - ---- -- 1200 ------- -- - -- ------ ---- - ------- 20--0 1--G--.----- --lB -- --- --- --- ---- 800 0 --- --------- --- - - --- - - - - - -- - - 6 0 --- - --- -- ------ - -------- ---- ------ ------- --- - 4 - ------- - - -- - - - ----- ----- -------- -------- -- 2 0 0 - ------I- ----------- 0% 20% 40% 60% 80% 100%
Patent AU-2013223740-B2 (AU)
Title: Catheter apparatus
Inventor: BAID RISHI
IPC: A61M25/06
Filed: 2013-02-13
Granted: 2015-11-26
Abstract: Intravenous catheter apparatus, comprising: a needle having a needle shaft, a needle tip at the distal end of the needle shaft and a needle hub mounted to the proximal end of the needle shaft, an intravenous catheter tube mounted to a cathether hub and a needle guard movable on the needle shaft, wherein the needle guard comprises: a base portion having a needle passage extending in an axial direction from a proximal side of the base portion through the base portion to a distal side of the base portion, first and second arms extending substantially in the axial direction from the distal side of the base portion and a distal wall which is transversely arranged at a distal region of the first arm, wherein a recess provided in the needle guard receives a stopping element for stopping movement of the needle shaft relative to the needle guard.
Patent AU-2013229416-B2 (AU)
Title: miRNA based treatment monitoring in multiple sclerosis
Inventor: KELLER ANDREAS
IPC: C12Q1/68
Filed: 2013-03-07
Granted: 2018-09-13
Abstract: The present invention relates to methods of determining whether a patient responds to a therapeutic treatment of multiple sclerosis (MS), of monitoring the course of multiple sclerosis (MS) in a patient, of determining the risk for a relapse of multiple sclerosis (MS) in a patient, and of adjusting the dose of a therapeutic drug applied for therapeutic treatment of multiple sclerosis in a patient. Said methods are based on the determination of the level of at least one miRNA in a test sample isolated from the patient. The present invention also relates to a method of identifying a compound suitable for the treatment of multiple sclerosis in a patient. Further, the present invention relates to the use of a polynucleotide or a polynucleotide set for detecting a miRNA to determine whether a patient responds to a therapeutic treatment of multiple sclerosis, to monitor the course of multiple sclerosis in a patient, to determine the risk of a relapse of multiple sclerosis in a patient, to adjust the dose of a therapeutic drug applied for therapeutic treatment of multiple sclerosis in a patient, and to identify a compound suitable for the treatment of multiple sclerosis in a patient. Furthermore, the present invention relates to a kit for determining whether a patient responds to a therapeutic treatment of multiple sclerosis, for monitoring the course of multiple sclerosis in a patient, for determining the risk of a relapse of multiple sclerosis in a patient, for adjusting the dose of a therapeutic drug applied for therapeutic treatment of multiple sclerosis in a patient, or for identifying a compound suitable for the treatment of multiple sclerosis in a patient comprising means for determining the level of at least one miRNA in a test sample isolated from a patient.
Patent AU-2013232062-B2 (AU)
Title: Large format electrochemical energy storage device housing and module
Inventor: WHITACRE JAY
IPC: H01M10/02
Filed: 2013-03-14
Granted: 2016-09-08
Abstract: An assembly includes non-load bearing housings, each housing including several cavities. Each cavity includes a stack of freely stacked electrochemical storage cells in the housings. Each electrochemical storage cell includes an anode electrode, a cathode electrode, and a separator located between the anode electrode and the cathode electrode. The assembly is configured such that pressure applied to the assembly is born by the freely stacked electrochemical storage cells.
Patent AU-2013235883-B2 (AU)
Title: Compositions comprising cocktails of antibacterial phages and uses thereof for the treatment of bacterial infections
Inventor: ALVES MENDES JOAO JOAO DUARTE
IPC: A61P31/04
Filed: 2013-03-19
Granted: 2018-01-04
Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections, in particular diabetic foot infections. More specifically, the present invention is directed to novel cocktails of bacteriophage strains F44/10, Fl 25/10, F770/05, F510/08, Fl 245/05, and/or variants thereof; and methods of using same in the treatment and prevention of bacterial infections, including cutaneous ulcers associated with diabetic foot infections, caused by, e.g., Staphylococcus aureus, Pseudomonas aeruginosa, and/or Acinetobacter baumannii. The cocktails are used as pharmaceutical compositions either alone or in further combination with other therapies, e.g., antibiotics, growth factors, or other standard, as well as non-standard, therapies for diabetic foot infections.
Patent AU-2013246882-B2 (AU)
Title: Compounds which inhibit neuronal exocytosis (II)
Inventor: FERRER MONTIEL ANTONIO
IPC: A61K8/64
Filed: 2013-04-12
Granted: 2017-10-19
Abstract: Compounds of general formula (I): R
Patent AU-2013249790-B2 (AU)
Title: Ring constrained analogs as Arginase inhibitors
Inventor: VAN ZANDT MICHAEL
IPC: A61P35/00
Filed: 2013-03-13
Granted: 2018-01-25
Abstract: The inventive boronic acid analogs are potent inhibitors of Arginase I and II activity. These compounds are candidate therapeutics for treating a disease or disorder associated with an imbalance in the activity or concentration of cellular arginase I and arginase II enzymes. The invention also provides pharmaceutical compositions of the inventive compounds and methods for using the compositions for therapy.
Patent AU-2013249991-B2 (AU)
Title: A tube securement system
Inventor: GULLIVER LAURENCE
IPC: A61M25/02
Filed: 2013-04-17
Granted: 2018-05-10
Abstract: The invention relates to systems for securing a tube (e.g. feeding tube) and/or a patient interface or a dermal patch to a user. One embodiment comprises a holder, an interface side of the holder attachable to the patient interface or the dermal patch for securing a feeding tube to the patient interface or the patch, the holder comprising at least a first channel or recess for receiving the feeding tube to couple the feeding tube to the patient interface. Another embodiment comprises a patient interface itself comprising a backing for positioning on a patient's face, a dermal patch having a patient side and an interface side, the patient side of the patch attachable to the user, the patch comprising at least a first flap portion attachable to the tube for affixing the tube to the patch, a two-part releasable connection arrangement for releasably securing the patient interface to the patch.
Patent AU-2013257104-B2 (AU)
Title: Delayed activation activatable stimulation assembly
Inventor: MERRON MATTHEW JAMES
IPC: E21B34/12
Filed: 2013-04-03
Granted: 2016-07-21
Abstract: A wellbore servicing apparatus comprising a housing defining an axial flowbore and comprising one or more ports providing a route of fluid communication between the axial flowbore and an exterior of the housing, a sliding sleeve disposed within the housing and comprising a seat and an orifice, the sliding sleeve being movable from a first position in which the ports are obstructed by the sliding sleeve to a second position in which the ports are unobstructed by the sliding sleeve, and the seat being configured to engage and retain an obturating member, and a fluid delay system comprising a fluid chamber containing a fluid, wherein the fluid delay system is operable to allow the sliding sleeve to transition from the first position to the second position at a delayed rate.
Patent AU-2013327480-B2 (AU)
Title: Transportable hose-test containers, systems and methods
Inventor: HENDERSON KIM
IPC: G01F13/00
Filed: 2013-10-01
Granted: 2016-08-11
Abstract: A transportable test system having a control room module, a first IMR test module, and a second IMR test module. The test modules may have fasteners that permit assembly into a unitary package of predetermined overall dimension (i.e. size and shape) such as a standard shipping container dimension. A first IMR test module may have a clean fluid provider and/or supply reservoir, and a second IMR test module may have a used fluid collector and/or collection reservoir. The system may include pressurization, hose restraint, fluid containment, module stabilization/mobilization, lifting, cleaning, and control subsystems.
Patent AU-2013343638-B2 (AU)
Title: Formulation for bispecific T-cell engagers (BITES)
Inventor: OLBRICH CARSTEN
IPC: C07K16/28
Filed: 2013-11-05
Granted: 2018-08-30
Abstract: The present invention relates to stable pharmaceutical compositions which contain polypeptides having at least two antigen binding domains and are particularly suitable for subcutaneous administration. The invention provides liquid compositions which minimize the formation of unwanted polypeptide aggregates (dimers and/or multimers). The present invention further provides a method of minimizing the aggregation of polypeptides having antigen binding domains in liquid compositions.
Patent AU-2013368440-B2 (AU)
Title: Device, method, and graphical user interface for navigating user interface hierarchies
Inventor: BERNSTEIN JEFFREY TRAER
IPC: G06F3/0485
Filed: 2013-11-11
Granted: 2017-01-05
Abstract: An electronic device with a touch-sensitive surface, a display, and one or more sensors to detect intensity of contacts displaying a lower-level user interface that is part of a user interface hierarchy, where the hierarchy includes at least three levels, including the lower-level user interface, an intermediate-level user interface and a higher-level user interface. The device also, while displaying the lower-level user interface, detects an input on a portion of the device that is associated with user interface hierarchy navigation and, in response to detecting the input, in accordance with a determination that the input meets first transition criteria, the device replaces display of the lower-level user interface with display of the intermediate-level user interface and in accordance with a determination that the input meets second transition criteria, the device replaces display of the lower-level user interface with display of the higher-level user interface.
Patent AU-2013372844-B2 (AU)
Title: Bet sensors, gaming tables with one or more bet sensors, and related methods
Inventor: CZYZEWSKI ZBIGNIEW
IPC: A63F9/24
Filed: 2013-12-20
Granted: 2016-12-15
Abstract: A bet sensor for determining the value of a wager includes a transparent cover having a bet placement surface configured and oriented to support a stack of gaming tokens thereon. A mirror arrangement is disposed on an opposing side of the transparent cover from the bet placement surface. The bet sensor also includes an image sensor. The mirror arrangement is located and configured to direct an image of a lateral side surface of a stack of gaming tokens supported on the bet placement surface onto the image sensor. A gaming table may incorporate such a bet sensor. Methods of forming such bet sensors include disposing a mirror arrangement on an opposing side of a transparent cover from a bet placement surface, and locating an image sensor such that the mirror arrangement directs an image of a lateral side surface of a stack of gaming tokens onto the image sensor.
Patent AU-2013392646-B2 (AU)
Title: System and method for actuating a mechanical diode clutch assembly
Inventor: RASZKOWSKI JAMES
IPC: F16D25/06
Filed: 2013-06-17
Granted: 2016-04-21
Abstract: The present disclosure provides an actuation assembly for applying a mechanical diode clutch. The clutch includes an outer member, an inner member, and a strut. The actuation assembly includes a plate having an apply portion and a plurality of legs, where each of the plurality of legs has a first end coupled to the apply portion and a second end adapted to couple to a shift sleeve. A mechanism is coupled to the apply portion of the plate. The mechanism includes at least one biasing member. The plate is moveable between an unapply position and an apply position such that a movement from the unapply position to the apply position induces contact between the mechanism and the strut.
Patent AU-2013407963-B2 (AU)
Title: Newly identified peptides for use in the induction of oral tolerance in young mammals
Inventor: BLANCHARD CARINE
IPC: A61P37/08
Filed: 2013-12-16
Granted: 2019-10-10
Abstract: The invention relates to newly identified peptides of that are capable of inducing tolerance to cow's milk, especially to β-lactoglobulin. The peptides may be administered to mammals, especially to young infants who are at risk of allergy to cow's milk proteins, to induce oral tolerance to cow's milk; they may also be administered to children or adults who are allergic to cow's milk to allow "desensitization" towards the allergenic milk proteins, especially β-lactoglobulin, to occur. The peptides may also be used to induce tolerance to goat's and buffalo's milk proteins, especially β-lactoglobulin. The peptides are capable of modulating the mammalian immune response to allergens.
Patent AU-2014224834-B2 (AU)
Title: Multilayered rotomoulded articles
Inventor: MAZIERS ERIC
IPC: B29C41/04
Filed: 2014-02-28
Granted: 2018-07-19
Abstract: The present invention relates to rotomoulded articles. More particularly, the present invention provides a rotomoulded article comprising: (i) at least one layer A comprising fibers embedded in a polymer resin; and (ii) at least one layer B comprising from 40 to 100 wt% of an aliphatic polyester. The present invention further provides methods for the manufacture of such articles.
Patent AU-2014238198-B2 (AU)
Title: Coupled enzyme-based method for electronic monitoring of biological indicator
Inventor: FRANCISKOVICH PHILLIP P
IPC: C12Q1/22
Filed: 2014-02-24
Granted: 2016-10-27
Abstract: A sterilization indicator system and method of using the system to determine efficacy of a sterilization process. The system includes a vial having a first compartment containing spores of one or more species of microorganism; a second compartment containing a growth medium with a disaccharide, an oligosaccharide or a polysaccharide in which the vial is free of monosaccharide; an enzyme, capable of acting upon the monosaccharide to yield reaction products and electron transfer, disposed on two or more electrodes adapted to carry an electrical signal resulting from the electron transfer, the pair of electrodes positioned to contact the combined contents of the first compartment and the second compartment during incubation; and an apparatus linked or linkable to the electrodes and adapted to detect and measure the electrical signal resulting from electron transfer when the enzyme acts upon the monosaccharide.
Patent AU-2014239503-B2 (AU)
Title: Rubber composition for tires and pneumatic tire
Inventor: TANAKA KEN
IPC: C08K5/25
Filed: 2014-03-18
Granted: 2016-06-16
Abstract: A rubber composition for a tire soft stiffener having improved crack resistance and low heat-buildup and containing (A) carbon black presenting specific particle size distribution behavior in an aggregate mass distribution curve, (B) bismaleimide, (C) alkylidene hydrazide, (D) disulfane, and (E) at least one compound selected from carbon black coupling agents comprising carboxylic hydrazides; and a heavy-duty tire using the rubber composition.
Patent AU-2014258386-B2 (AU)
Title: DNA binding protein using PPR motif, and use thereof
Inventor: YAMAMOTO TAKASHI
IPC: C12N9/16
Filed: 2014-04-22
Granted: 2018-10-25
Abstract: [Problem] Based on the prediction that the rules for DNA recognition possessed by a PPR motif may also be used in DNA recognition, perform analysis of PPR protein that is active in DNA binding, and search for a PPR protein that has such characteristics. The present invention addresses the aforementioned problem by means of a protein that can bind DNA base-selectively or DNA base sequence-specifically, and that contains a plurality of, preferably 2-30, more preferably 5-25, and even more preferably 9-15, PPR motifs having the structure in formula 1 (in formula 1: Helix A is a part that can form an α helix structure; X is a part that does not exist or that comprises 1-9 amino acids; Helix B is a part that can form an α helix structure; and L is a part that comprises 2-7 amino acids), the PPR motif having a specific combination of three amino acids corresponding to the DNA base or target base sequence: first A.A. of Helix A and the 4th A.A. of Helix A in formula 1, together with the "ii"(-2)th A.A. contained in L. (Helix A)-X-(Helix B)-L (formula 1)
Patent AU-2014266400-B2 (AU)
Title: Stacking-type header, heat exchanger, and air-conditioning apparatus
Inventor: MATSUDA TAKUYA
IPC: F25B39/04
Filed: 2014-05-13
Granted: 2016-05-26
Abstract: This laminated header (2) is provided with a first plate-shaped body (11) in which a plurality of first exit channels (11A) are formed and a second plate-shaped body (12) attached to said first plate-shaped body (11). Distribution channels (12A) via which a refrigerant flowing in via a first entrance channel (12a) is distributed to and flows out via the first exit channels (11A) are formed in the second plate-shaped body (12). Said distribution channels (12A) include forked channels (12b) that each have an opening, a first straight section parallel to the direction of gravity, and a second straight section parallel to the direction of gravity, with the bottom end of the first straight section connecting to the opening via a first connecting section and the top end of the second straight section connecting to the opening via a second connecting section. At least part of each first connecting section is not parallel to the direction of gravity, as is at least part of each second connecting section. In each forked channel (12b), the refrigerant flows into the bottom end of the first straight section and the top end of the second straight section from the opening via the first and second connecting sections and flows out from the top end of the first straight section and the bottom end of the second straight section.
Patent AU-2014267632-B2 (AU)
Title: Drilling rig rod handling apparatus
Inventor: JELGERT JOHAN
IPC: E21B19/20
Filed: 2014-04-09
Granted: 2017-08-17
Abstract: Drill rod handling apparatus configured to feed rods to and from a drill string created by a drill rig. The apparatus comprises a gripper unit configured to contact and hold a rod to be transported to the drill rig and an alignment tool mounted at the gripper unit to provide correct mating of the rod ends during coupling.