baber/WOPTO huggingface dataset:
Patent PT-1648413-E (PT)
Title: Pharmaceutical compositions of short-acting sedative hypnotic agent
Inventor: JENKINS THOMAS E
IPC: A61K31/20
Filed: 2004-07-21
Abstract: The invention provides pharmaceutical compositions comprising a phenylacetic acid ester compound useful for inducing or maintaining general anesthesia or sedation in mammals, methods for preparing such compositions, and methods for inducing or maintaining anesthesia or sedation using such compositions.
Patent PT-1663194-E (PT)
Title: Use of saha for treating mesothelioma
Inventor: BACOPOULOS NICHOLAS G
IPC: A61K/
Filed: 2004-08-26
Abstract: The present invention relates to methods of treating cancers, e.g., mesothelioma or lymphoma. More specifically, the present invention relates to methods of treating mesothelioma or diffuse large B-cell lymphoma (DLBCL), by administration of pharmaceutical compositions comprising HDAC inhibitors, e.g., suberoylanilide hydroxamic acid (SAHA). The oral formulations of the pharmaceutical compositions have favorable pharmacokinetic profiles such as high bioavailability and surprisingly give rise to high blood levels of the active compounds over an extended period of time. The present invention further provides a safe, daily dosing regimen of these pharmaceutical compositions, which is easy to follow, and which results in a therapeutically effective amount of the HDAC inhibitors  in vivo.
Patent PT-1691813-E (PT)
Title: Ready-for-use injectable solution of 9-((1,3-dihydroxypropan-2-iloxy)methyl)-2-amine-1h-purin-6(9h)-one, sterile, stable; closed system for packing the solution, process for eliminating alkaline residuals of 9-((1,3-dihydroxypropan-2-iloxy)methyl)-2-
Inventor: PERILLO HENO
IPC: B32B27/32
Filed: 2004-11-25
Abstract: The present invention describes a sterile, stable and ready-for-use injectable solution comprising 9-((1,3-dihydroxypropan-2-iloxy)methyl)-2-amino-1H-purin-6(9H)-one in glucose 5% aqueous solution or sodium chloride 0-9% aqueous solution. It also describes a closed system used for packing the solution, which consists of a flexible bag manufactured with a tri-laminated material. The present invention also describes a process for eliminating the residual alkalinity that is present in the 9-((1,3-dihydroxypropan-2-iloxy)methyl)-2-amino-1H-purin-6(9H)-one, so obtaining crystals that are free from alkaline residues and suitable for the direct preparation of the solution. The present invention relates to the medical and therapeutic areas, mainly for treating immunodepressed patients carrying viral infections.
Patent PT-1634789-E (PT)
Title: Vacuum booster with a better system to keep the booster idle state
Inventor: VERBO ULYSSE
IPC: B60T13/569
Filed: 2005-08-24
Abstract: The servomotor has a piston (22) integrated to an apron (15) and communicating braking efforts to a piston of a master cylinder (31). A permanent magnet (40) couples magnetically the apron or a magnetically permeable plate integrated to the apron to a rear wall (13) or a magnetically permeable piece integrated to the wall. The piston (22) is maintained in a rest position, in absence of braking control.
Patent PT-1752628-E (PT)
Title: Thermostatic valve for lubrification circuits of internal-combustion engines for motor vehicles
Inventor: TRIBERTI FRANCO
IPC: G05D23/02
Filed: 2005-12-30
Abstract: Described herein is a thermostatic valve for lubrication circuits for internal-combustion engines for motor vehicles comprising a body (1) having an inlet (3), and a first outlet (4) and a second outlet (5), opening/closing of which is controlled by an open/close element carried by the stem (8) of a thermostatic-valve unit (6). The open/close element consists of a drawer (9) with a set of three annular elements (12, 13, 14) designed to provide a control sequence with five successive stages.
Patent PT-1709019-E (PT)
Title: Thiazole derivatives and use thereof
Inventor: QUATTROPANI ANNA
IPC: A61K31/427
Filed: 2005-01-11
Abstract: The present invention is related to thiazole derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neturodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
Patent PT-1856031-E (PT)
Title: 2-arylpropionic acid derivatives and pharmaceutical compositions containing them
Inventor: ALLEGRETTI MARCELLO
IPC: C07D277/30
Filed: 2005-12-13
Abstract: The present invention relates to selected (R)-2-phenyl-propionamides and (R)-2-phenyl-sulfonamides with a hydrogen bond acceptor atom/group in a well defined position in the chemical space. These compounds show a surprising potent inhibitory effect on C5a induced human PMN chemotaxis. The compounds of the invention absolutely lack of CXCL8 inhibitory activity. Said compounds are useful in the treatment of pathologies depending on the chemotactic activation of neutrophils and monocytes induced by the fraction C5a of the complement. In particular, the compounds of the invention are useful in the treatment of sepsis, psoriasis, rheumatoid arthritis, ulcerative colitis, acute respiratory distress syndrome, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of injury caused by ischemia and reperfusion.
Patent PT-1851143-E (PT)
Title: Scraper blade and method of manufacturing the same
Inventor: ABRAHAM ROBERT
IPC: B65G45/12
Filed: 2006-10-09
Abstract: A scraper blade adapted to scrape off material from a surface has a scraper tip at one end and a mounting base at its other end and is tapered towards the tip at least in the outer end of the scraper blade, its scraper blade portion which extends from the tip and to a point adjacent to or in the mounting base being made with at least two layers, which extend longitudinally along said scraper blade portion, and is characterised in that at least one first layer is made of polyurethane with a lower hardness and a higher abrasion resistance than at least one second layer which is mainly made of polycarbonate plastic, said at least one second polycarbonate plastic layer being adapted to reinforce and stiffen said at least one first layer, which constitutes a main contact surface against said surface.
Patent PT-1847332-E (PT)
Title: Apparatus and method for manufacturing spiral duct
Inventor: CHA KYU-SEOK
IPC: B21C37/12
Filed: 2007-03-27
Abstract: Provided are an apparatus and method for manufacturing a spiral duct. The apparatus includes: a first edge forming roll assembly (100) for forming dual bent parts at both straight edges of a metal band (300); a cutting roll assembly (200) for cutting the metal band (300) extracted from the first edge forming roll assembly (100) in a waved shape by periodically varying a horizontal rotation angle or in a straight shape in its longitudinal direction; a second edge forming roll assembly (400) disposed downstream of the cutting roll assembly (200) in feeding direction of the metal band (300) to form a single bent part of the waved edges of the cut metal band; and a seaming device (500) for coupling a single bent part with the dual bent part winding the cut metal band in a spiral shape. The method includes: supplying a metal band (300); forming an outward bent part, a vertically bent part, and an inward bent part at both straight edges of the metal band; periodically varying a horizontal rotation angle of a cutting roll assembly (200) to cut the metal band in a waved shape in its longitudinal direction to divide the metal band into two cut metal bands; forming a single bent part at the waved edge and a dual bent part at the straight edge; and coupling the single bent part with the dual bent part winding the cut metal band. Therefore, since a horizontal rotation angle of a cutting roll assembly (200) is periodically varied to continuously cut a metal band (300) along a straight line and a waved line, it is possible to form a duct in which straight connection ducts are integrally formed with a curved duct. In addition, since the cut parts of the metal band are formed smoother, it is possible to precisely and securely couple a single bent part with a dual bent part at their seam parts.
Patent PT-717777-E (PT)
Inventor: MILLER SAMUEL I III
IPC: A61P31/04
Filed: 1994-07-07
Abstract: A bacterial cell the virulence of which is attentuated by a first mutation in a PhoP regulon and a second mutation in an aromatic amino acid synthetic gene and bacterial cells the virulence of which is attenuated by a mutation in one or more PhoP-activated genes or one or more PhoP-repressed genes.
Patent PT-801062-E (PT)
Inventor: ODA TOSHIAKI
IPC: C07D239/69
Filed: 1995-12-19
Abstract: The present invention is directed to a pyrimidine derivative of the following formula (1) or a salt of the derivative: <CHEM> Äwherein R<1> represents a lower alkyl group; each of R<2> and R<3> represents H, alkyl, or alkoxy; each of R<4> and R<5> represents H or alkyl; R<6> represents alkyl, -OR<7>, or -NR<8>R<9>; and n is a number between 0 and 3 inclusive (wherein each of R<7>, R<8>, and R<9> represents H, alkyl, aryl, aralkyl, amino, a heterocyclic ring, etc.)Ü, as well as to a medicine containing the derivative or salt as the active ingredient. The present compounds exhibit strong binding inhibitory activity against endothelin having potent vasoconstrictive effect and cell proliferation effect. Therefore, the compounds are effective as remedies for various diseases including circulatory diseases.
Patent PT-845988-E (PT)
Inventor: NICHOLS DAVID E
IPC: C07D491/056
Filed: 1996-08-16
Abstract: The present invention is directed to a novel dopamine receptor ligands of the formula:pharmaceutical formulations of such compounds, and a method using such compounds for treating a patient suffering from dopamine-related dysfunction of the central or peripheral nervous system.
Patent PT-971594-E (PT)
Inventor: FLOMEN EDWARD
IPC: A22C13/02
Filed: 1997-12-09
Abstract: A holder for retaining shirred gut sausage casing comprising an elongated, flexible, self-supporting, flattened tube having a longitudinal uninterrupted slit. The flattened tube comprises a pair of opposed parallel walls terminating in longitudinal edges at the slit. The flattened tube is formed from a relatively firm, flexible sheet material having a low coefficient of friction.
Patent PT-859350-E (PT)
Inventor: SAIZ CARLOS
IPC: F21V25/00
Filed: 1998-02-05
Abstract: Unit uses bulbs (19) to illuminate a translucent surface (37). It includes attachments for the surface and a supporting, insulating, protective hood (1). Its profiled sections are end to end. Each forms a pair of wings diverging from the top. The profiled, electrically-conductive, sections (15) are internally concave and fit within the wings to form light reflectors. At the top these butt against a projection where the wings join. Each conductive section is at a different electrical polarity, and can supply electrical energy over the entire length of the support. The upper ends of the profiles (15) fold, the fold butted against a central projection, forming the supply rails. This permits the bulbs and their contacts to be placed in any required position along the unit.
Patent PT-1044376-E (PT)
Inventor: MENDEL-HARTVIG IB
IPC: G01N33/543
Filed: 1998-12-30
Abstract: A method for use in a flow matrix, which utilizes biospecific affinity reactions to detect an analyte in the sample, and which comprises allowing the sample comprising the analyte and an analytically detectable reactant (Reactant*) to migrate through flow channels in a flow matrix to a detection zone located in the matrix, in which there is a firmly anchored biospecific affinity reactant (Capturer), and capturing the Reactant* in the detection zone in an amount related to the amount of analyte in the sample. The Reactant* has labeled particles of an analytically detectable group, and the Capturer is anchored to the matrix by immobilized particles which exhibit hydrophilic groups on their surface. A test kit comprises a flow matrix having a detection zone in which there is a firmly anchored biospecific affinity reactant (Capturer), and an analytically detectable reactant (Reactant*). The Reactant* has labeled particles of an analytically detectable group, and the Capturer is anchored to the matrix by immobilized particles which exhibit hydrophilic groups on their surface.
Patent PT-1097410-E (PT)
Inventor: MORFINO GIUSEPPE
IPC: G05B19/404
Filed: 1999-07-05
Abstract: A system and a process are described for performing the Static Error Compensation on numerically controlled machine tools. The process comprises the steps of: connecting a measuring laser device (5) to a numerically controlled machine tool (1); automatically sending a point 0 of the machine (1) to the laser device (5); sending commands for taking m measure points of the machine (1) from the control (3) to the laser device (5); automatically detecting the measure points and sending consolidated data from the laser device (5) to the control (3); producing a model of static errors of the machine (1); executing the Static Error Compensation depending on said produced model.
Patent PT-1137527-E (PT)
Title: Single extruder screw for efficient blending of immiscible polymeric materials
Inventor: JANA SADHAN C
IPC: B29C48/67
Filed: 1999-10-18
Abstract: A single extruder screw is presented which includes a plurality of equidistant undercut barriers disposed in a preselected pattern within the channel of an extrusion screw. The undercut barriers are disposed in the first metering stage and second metering stage and provide increased dispersive and distributed mixing for highly viscous difficult to blend materials. In another embodiment the single extruder includes a slotted blister ring, having slots and lands disposed thereon, positioned between the first metering stage and the vent zone to further increase the amount of mixing.
Patent SG-41992-G (SG)
Title: Method for making a yarn,and apparatus for carrying out the method
IPC: D02J1/22
Filed: 1992-04-15
Abstract: A method is described for making a yarn, wherein a synthetic partially oriented multifilament yarn is delivered at a first speed to a pin, guided around the pin for between 270 DEG  and 360 DEG , preferably for about 360 DEG , and then taken off at a second speed. This second speed is higher than the first speed. Thereafter the multifilament yarn is wound up. The pin used is an unheated pin having a diameter of less than 10 mm. Immediately after the multifilament yarn has been laid around the pin, the multifilament yarn is heated to a temperature between 100 DEG C and 250 DEG C for from 0.01 s to 10 s. 
<??>There is also described an apparatus for carrying out the method. This apparatus comprises a first delivery system for hauling off the multifilament yarn, preferably off a package, a pin wrapped by the yarn, a second delivery system for hauling the yarn off the pin, and a winder. The pin is constructed as an unheated pin having a diameter of less than 10 mm. A heater is situated between the pin and the second delivery system. 
<IMAGE>
Patent IE-820261-L (IE)
Title: N-benzoyl-n'-phenoxyphenylureas, pesticides.
IPC: A01N47/34
Filed: 1982-02-05
Abstract: 1. An N-benzoyl-N'-phenoxyphenylurea of the formula  see diagramm : EP0057888,P13,F1  where Z is chlorine in the 3-position or methyl, R is fluorine, chlorine, bromine, phenoxy which is unsubstituted or substituted by fluorine, chlorine, bromine, or haloalkyl or haloalkoxy of up to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms which is unsubstituted or substituted by chlorine and/or fluorine, alkyl of 1 to 3 carbon atoms, or 2-hydroxy-hexahaloisopropyl, halogen being fluorine and/or chlorine, Y is hydrogen, fluorine or chlorine, X is fluorine, chlorine, bromine, methyl or nitro, the substituents X being identical or different, and n is 2 or 3, or where Z can also be hydrogen when R is phenoxy which is unsubstituted or substituted by fluorine, chlorine, bromine, or haloalkyle or haloalkoxy of up to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms which is unsubstituted or substituted by chlorine and/or fluorine, alkyle of 1 to 3 carbon atoms, or 2-hydroxyhexahaloisopropyl, halogen being fluorine and/or chlorine, Y is hydrogen, fluorine or chlorine, X is fluorine, chlorine, bromine, methyl or nitro, the substituents X being identical or different, and n is 1, 2 or 3, or where Z can also be hydrogen when R is fluorine or bromine, Y is chlorine, X is fluorine, chlorine, bromine, methyl or nitro, and n is 1, or where Y can also be bromine or nitro when R is fluorine, chlorine, bromine, phenoxy which is unsubstituted or substituted by fluorine, chlorine, bromine, or haloalkyl or haloalkoxy of up to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms which is unsubstituted or substituted by chlorine and/or fluorine, alkyl of 1 to 3 carbon atoms, or 2-hydroxy-hexahaloisopropyl, halogen being fluorine and/or chlorine, Z is hydrogen, chlorine in the m-position or methyl, X is fluorine, chlorine, bromine, methyl or nitro, the substituents X being identical or different, and n is 1, 2 or 3.
Patent IE-810371-L (IE)
Title: Use of prolonged tack toners in the preparation of electric¹circuits
IPC: H05K3/12
Filed: 1981-02-24
Abstract: Preparation of an electrically conductive pattern by adhering a prolonged tack toner which is activated by heating to the toner-receptive image areas of an inert substrate, the temperature is reduced and to the activated toner is applied a prolonged tack toner having conductive metal particles and glass frit as components; optionally the steps of heating, temperature reduction and toner application are repeated at least one time, and then the toned image is burned and fired. An electrically conductive pattern is obtained which is useful, for example, as an electric circuit. The process is also useful in the application of resistor and dielectric materials.
[US4303698A]
Patent IE-810391-L (IE)
Title: Trihydroxypiperidine derivatives.
IPC: C07D211/46
Filed: 1981-02-25
Abstract: The invention relates to 3,4,5-trihydroxypiperidine compound of Formula (I) as methods for the preparation of said compounds. Also included in the invention are compositions containing said piperidine compounds and methods for the use of said piperidine compounds and compositions. The invention further includes veterinary compositions containing said piperidine compounds and their use in animal nutrition.
Patent IE-780418-L (IE)
Title: Cot mattress
IPC: A61G7/05
Filed: 1978-02-28
Abstract: A mattress of the type used on ambulance cots and similar patient transporting devices, the mattress having a cover containing patient supporting cushions, the cushion in the area of the patient's head and back overlying one or more stiffening panels which, upon removal of the overlying cushions, provide a firm support for the administration of cardiopulmonary resuscitation, the mattress preferably having an articulated head section which may be inclined relative to the back section to place the patient's head in a hyper-extended position.
[US4168554A]
Patent IE-870575-L (IE)
Title: Alpha-heterocycle substituted toluonitriles.
IPC: A61K31/14
Filed: 1987-03-06
Abstract: Heterocyclylalkylbenzonitrile derivs. of formula (I) and their salts are new (where R, R' = H or 1-7C alkyl; or R+R' when on adjacent C atoms, together with the benzene ring form a naphthalene or tetrahydronaphthalene ring system; R1 = H; R2 = H, 1-7C alkyl, 2-7C alkenyl, aryl, aryl-(1-7C)alkyl, 3-6C cycloalkyl or (3-6C)cycloalkyl-(1-7C)alkyl; or R1+R2 = 1-7C alkylidene opt. substd. by mono- or di-aryl, or 4-6C n-alkylene, n-alkylene substd. by 1-7C alkyl or 2-4C n-alkylene bridged by o-phenylene, to form with the attached C a corresp. opt. substd. or benzo-fused 5-, 6- or 7-membered ring; W = 1-imidazolyl, 1,2,4- or 1,3,4-triazol-1-yl or 3-pyridyl each opt. substd. by 1-7C alkyl). 1-Cyano-4-imidazolylnaphthalenes of formula (II) and their salts are new (where R1' = H; R2' = H, 1-7C alkyl, Ph, 1-7C alkylthio, Ph-(1-7C)alkylthio, PhS, pyridyl, thienyl or benzyl, or Ph, Ph-(1-7C)alkylthio, PhS or benzyl each ring mono-substd. by CN, 1-7C alkyl, 1-7C alkoxy, OH, 1-7C alkanoyloxy, aroyloxy, NO2, halogen, CF3, 1-7C alkanoyl, aroyl, 1-7C alkylsulphonyl, or CONH2 or SO2NH2 both opt. substd. by 1 or 2 1-7C alkyls; or R1'+R2' = 1-7C alkylidene, benzylidene, diphenylmethylidene or 4-6C n-alkylene; R3 = H or 1-7C alkyl).
Patent IE-780605-L (IE)
Title: 1, 2-DIHYDRO-3H-PYRROLO [1,2-a] PYRROLES
IPC: C07D207/34
Filed: 1978-03-29
Abstract: Novel 5-(2-pyrroyl) and 5-(N-lower alkyl-2-pyrroyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid compounds represented by the formula: <IMAGE> and the pharmaceutically acceptable, non-toxic esters and salts thereof, wherein each of R and R1 is independently hydrogen or a lower alkyl group having from 1 to 4 carbon atoms and process for the production of such compounds; 5-(N-methyl-2-pyrroyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid is representative of the class. These compounds are useful as anti-inflammatory analgesic and anti-pyretic agents and as smooth muscle relaxants.
[US4097579A]
Patent IE-890611-L (IE)
Title: Flame retardant, high temperature resistant polyimide fibres
IPC: D04H3/00
Filed: 1989-02-24
Abstract: The present disclosure describes flame-retardant, high-temperature resistant polyimide fibers, nonwovens made from said fibers, as well as the fibers and molded articles obtained after a heat treatment. A composite of such fibers is heated to a temperature in the glass transition range of the fiber, i.e. between 280 DEG  and 350 DEG  C. This heat treatment develops a contraction force of 0.3 to 1.1 cN in the fibers which results in a fiber shrinkage of between 20 and 60% and the formation of cohesive bonds. The fibers of the invention enable the manufacture of molded articles that are particularly strong, have a high temperature resistance and flame-retardant properties, while having a relatively low density.
Patent IE-810705-L (IE)
Title: Easy-opening can end
IPC: B65D17/34
Filed: 1981-03-27
Abstract: A tab for easy opening ends including a lifting end and an opening end and spaced side legs is improved by the use of finger means extending from the opening end towards the lifting end, the finger means including flanges which stiffen the finger. The lifting end is formed of a smooth unbroken curl of sheet material.
[US4286728A]
Patent IE-34346-L (IE)
Title: Mounting device for thyristor
IPC: H01L23/488
Filed: 1970-06-29
Abstract: 1,273,204. Semi-conductor devices. LANSING BAGNALL Ltd. 26 June, 1970 [2 July, 1969], No. 33380/69. Heading H1K. A mounting for a thyristor comprises a heatsink base 12 on to which the thyristor 10 is clamped by a clamping structure having a deformable tube 15 pressed down on to the thyristor and deformed by a cup-like cover 21, the pressure exerted by the tube 15 being independent of the extent of its deformation. A terminal 14 leading to the thyristor passes through the mounting, electrical insulation being provided by a nylon cap 20. The clamping of the cover 21 on to tube 15 is provided by bolts 26 which engage threaded holes 27 in the heat sink. The deformation of the tube 15 takes the form of a plurality of circumferentially extending corrugations.
[GB1273204A]
Patent FI-830718-L (FI)
Inventor: LEHMANN KLAUS
IPC: A61K9/32
Filed: 1983-03-03
Abstract: What are disclosed are methods for dispersing a powdered salt-forming synthetic resin in water in the presence of an agent forming a salt with said resin, methods for coating pharmaceutical dosage forms with a dispersion made by such a method, and powdered mixtures of a salt forming resin and salt forming agent for dispersion in water.
Patent FI-853070-L (FI)
Inventor: GRESSER ROBERT
IPC: C11D3/12
Filed: 1985-08-09
Abstract: Aqueous zeolite suspensions, e.g., of type A and especially detergent type 4A, are stabilized and maintained pumpable by adding thereto an effective stabilizing amount of at least one alkaline earth metal cation, advantageously magnesium.