baber/WOPTO huggingface dataset:
Patent NZ-721643-A (NZ)
Title: Compositions and methods for antibodies targeting factor p
Inventor: KUNZ CHRISTIAN CARSTEN SILVESTER
IPC: C07K16/18
Filed: 2012-12-17
Abstract: Disclosed is a composition comprising a first antibody, or antigen binding fragment thereof, that binds Factor P, and a second antibody, or antigen binding fragment thereof, that binds C5, wherein said composition inhibits the alternative complement pathway. Also disclosed is the use of such a composition in the manufacture of a medicament for treating age related macular degeneration and for inhibiting the alternative complement pathway.
Patent NZ-722599-A (NZ)
Title: Isoindoline compositions and methods for treating neurodegenerative disease
Inventor: RISHTON GILBERT
IPC: A61K31/404
Filed: 2015-01-30
Abstract: Isoindoline sigma-2 receptor antagonist compounds, pharmaceutical compositions comprising such compounds, and methods for inhibiting Abeta- associated synapse loss or synaptic dysfunction in neuronal cells, modulating an Abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with Abeta pathology are provided.
Patent NZ-723938-A (NZ)
Title: A fastener and installation device
Inventor: NIELSEN WADE IAN
IPC: F16B2/22
Filed: 2015-03-12
Abstract: A fastener and a fastener installation device which enables cables to be installed in hard to reach places safely and quickly. The fastener including a body forming a loop; a first connector formed at a first end of the body; and a second connector formed at a second end of the body; wherein the first connector is complementary with the second connector. The first connector of the first fastener connects with a second connector of a second fastener and the second connector of the first fastener connects with a first connector of a third fastener to form a chain of fasteners. The installation device including a hollow body and a cap rotatably mounted to an end of the hollow body which includes an aperture allowing a top fastener to pass through the aperture when the cap is in a first position.
Patent NZ-726046-A (NZ)
Title: A process, apparatus and system for treating fruits or vegetables
Inventor: HASTINGS JEFFREY JOHN
IPC: A23B7/04
Filed: 2015-04-10
Abstract: A process for treating avocados to minimize browning upon subsequent processing, handling, and storage, the method comprising:(a) separating the mesocarp from the pericarp and the endocarp of the avocado; (b) blanching said mesocarp by contacting the mesocarp with steam for a pre-determined blanching time period at a pressure less than or equal to atmospheric pressure within a blanching chamber, wherein at least a portion of the blanching chamber is not sealed from atmosphere; (c) cooling the blanched mesocarp; and (d) freezing the cooled mesocarp to obtain at least partially frozen mesocarp. The disclosed process reduces oxidation and enzymatic degradation of avocado flesh due to environmental exposure while preserving its organoleptic properties.
Patent NZ-735118-A (NZ)
Title: Glucosylceramide synthase inhibitors for the treatment of diseases
Inventor: WANG BING
IPC: C07D265/02
Filed: 2016-03-10
Abstract: Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).
Patent NZ-737465-A (NZ)
Title: A paver
Inventor: PINSON CRAIG STEVEN
IPC: E01C19/48
Filed: 2016-05-19
Abstract: A paver mountable to a vehicle to provide propulsion and hydraulic power to the paver, wherein the paver includes: a drive system coupling for mounting the vehicle to the paver; hydraulic mounts to connect with hydraulic power from the vehicle; a solids handling assembly for receiving paving material and for delivering paving material to a paving site; a screed assembly with a screed plate which is hydraulically adjustable in extension, height and grade; wherein, paving material delivered to the paving site is shaped by the screed assembly as the paver is propelled forward to produce a paved surface; the disclosed mountable paver overcome the problems associated with prior art pavers which incorporate drive systems together with the paving system in a specialized single piece of plant.
Patent NZ-750559-A (NZ)
Title: Complete genome sequence of the methanogen methanobrevibacter ruminantium
Inventor: ALTERMANN ERIC HEINZ
IPC: C12N15/31
Filed: 2010-08-27
Abstract: Disclosed is a group of isolated polypeptides or peptides comprising extracellular domains of amino acid sequences of Methanobrevibacter ruminantium. These isolated polypeptides or peptides are useful in the production of vaccines for treating ruminant animals.
Patent NZ-755628-A (NZ)
Title: Engineered phenylalanine ammonia lyase polypeptides
Inventor: HUISMAN GJALT
IPC: A61K38/51
Filed: 2018-02-12
Abstract: The present invention provides engineered phenylalanine ammonia lyase (PAL) polypeptides and compositions thereof, as well as polynucleotides encoding the engineered phenylalanine ammonia lyase (PAL) polypeptides. In some embodiments, the engineered PAL polypeptides are optimized to provide enhanced catalytic activity, as well as reduced sensitivity to proteolysis and increased tolerance to storage at elevated temperatures. In some embodiments, the engineered PAL polypeptides contain fewer phenylalanine residues than wild-type PAL polypeptides. The present invention also provides methods for the use of the compositions comprising the engineered PAL polypeptides for therapeutic and industrial purposes.
Patent PT-100377-A (PT)
Title: Unit for irrigation system using spraying
Inventor: SAMPERIO JOSE GOMEZ
IPC: B05B/
Filed: 1992-04-10
Abstract: System which consists of a water-dispersion tube 13, from which descends, in the vicinity of one of the ends, a vertical telescopic tube 11 for coupling to the irrigation nozzles, all this being supported by a structure provided with drive wheels 1 at the ends capable of moving the assembly automatically in a movement guided by the sliding of feelers (feeler gauges) 7 on an orientation cable 8, whilst, in the zone transversely coincident with the vertical tube 11 there are two wheels 2, perpendicular to the movement wheels, which are movable vertically, with the possibility of being suspended without bearing on the ground for movement or of being supported, at this end raising the structural assembly with a view to the mobility of the assembly rotationally about the vertical tube 11 in the irrigation operation. <IMAGE>
Patent PT-104086-A (PT)
Title: Processo para monitorização do sucesso da aplicação de um fluido a um alvo biológico não estático e sistema para sua execução
Inventor: TRAVASOS ANTONIO CASANOVA TAVA
IPC: B67D3/00
Filed: 2008-06-05
Abstract: O PRESENTE INVENTO DIZ RESPEITO A UM PROCESSO PARA MONITORIZAÇÃO DO SUCESSO DA APLICAÇÃO DE UM FLUIDO, DISPENSADO POR UM RECIPIENTE 33 PARA DISPENSAR FLUIDOS INSERIDO NUM DISPOSITIVO 1, A UM ALVO, COMPREENDENDO OS SEGUINTES PASSOS: A) DETECÇÃO DA INCLINAÇÃO DO DISPOSITIVO 1; B) EMISSÃO DE UM ALARME QUANDO A INCLINAÇÃO DO DISPOSITIVO 1 ATINGIR UM DETERMINADO VALOR; C) DETECÇÃO DE UM AUMENTO DE PRESSÃO NO RECIPIENTE 33 PARA DISPENSAR FLUIDOS; D) VERIFICAÇÃO DA OCORRÊNCIA SIMULTÂNEA DO ALARME DE INCLINAÇÃO E DO AUMENTO DE PRESSÃO NO RECIPIENTE PARA DISPENSAR FLUIDOS; E) SINCRONIZAÇÃO DO INÍCIO DA AQUISIÇÃO DE IMAGENS COM A OCORRÊNCIA DO ESTADO DESCRITO EM D); F) CAPTURA ELECTRÓNICA DE UMA PLURALIDADE DE IMAGENS DO ACTO DE ADMINISTRAÇÃO DA SUBSTÂNCIA, EM QUE AS IMAGENS CORRESPONDEM A INSTANTES DISTINTOS E SEQUENCIAIS; G) ANÁLISE DAS IMAGENS RECOLHIDAS PARA DETERMINAÇÃO DO ESTADO DO ALVO; H) ANÁLISE DAS IMAGENS PARA IDENTIFICAÇÃO DO ALVO; I) ANÁLISE DAS IMAGENS PARA DETERMINAÇÃO DA LOCALIZAÇÃO DA GOTA A CADA INSTANTE; J) RELACIONAMENTO DAS ANÁLISES DE G), H) E I) PARA DETERMINAÇÃO DO SUCESSO DA APLICAÇÃO DA GOTA; K) EXPOSIÇÃO DOS RESULTADOS. O INVENTO REFERE-SE AINDA A UM SISTEMA PARA A EXECUÇÃO DO PROCESSO ANTERIORMENTE REFERIDO.
Patent PT-104121-A (PT)
Title: Dispositivo para leitura de identificadores de radiofrequência garantindo confinamento volumétrico da região de detecção
Inventor: COSTA JORGE MANUEL LOPES LEAL
IPC: G01V15/00
Filed: 2008-06-28
Abstract: A PRESENTE INVENÇÃO REFERE-SE A UM SISTEMA DE DETECÇÃO E IDENTIFICAÇÃO DE OBJECTOS COMPORTANDO ETIQUETAS DE IDENTIFICAÇÃO POR RADIOFREQUÊNCIA (RFID TAGS). O SISTEMA COMPREENDE UM DISPOSITIVO COMPOSTO POR UMA LINHA DE TRANSMISSÃO (6) (MICRO-STRIP), INCLUINDO SUBSTRATO DIELÉCTRICO DE BAIXA PERMITIVIDADE (8) E UM PLANO METÁLICO DE REFERÊNCIA (7). O DISPOSITIVO ASSEGURA COBERTURA E DETECÇÃO DE TODOS OS OBJECTOS EM CAMPO PRÓXIMO EM UHF, GARANTE O CONFINAMENTO DOS CAMPOS NO VOLUME DE INTERESSE, GARANTE O ISOLAMENTO EM RELAÇÃO A DISPOSITIVOS ADJACENTES E TEM UM CUSTO DE PRODUÇÃO MUITO REDUZIDO. O PRESENTE INVENTO É APLICÁVEL, A TÍTULO DE EXEMPLO, NOS SECTORES DO RETALHO (POR EXEMPLO, EM LIVRARIAS, LOJAS DE VESTUÁRIO, SUPERMERCADOS E FARMÁCIAS), DA DISTRIBUIÇÃO OU DA INDÚSTRIA EM PONTOS DE LEITURA DE RFID OU EM ESTEIRAS DOS TERMINAIS DE PAGAMENTO EM SUPERMERCADOS E TAMBÉM EM ESTEIRAS DE TRANSPORTE DE OBJECTOS EM ARMAZÉNS OU EM LINHAS DE PRODUÇÃO. O INVENTO FOI DESENVOLVIDO NO INSTITUTO DE TELECOMUNICAÇÕES EM COLABORAÇÃO COM A CREATIVESYSTEMS.
Patent PT-117178-A (PT)
Title: Composição para manufatura aditiva por impressão por jato de ligante, método de preparação e método para manufatura aditiva por impressão por jato de ligante de um objeto conformado
Inventor: JOSÉ MARTINHO MARQUES DE OLIVEIRA
IPC: B33Y80/00
Filed: 2021-04-15
Abstract: COMPOSIÇÃO PARA MANUFATURA ADITIVA POR IMPRESSÃO POR JATO DE LIGANTE, COMPREENDENDO UM MATERIAL PARTICULADO CERÂMICO SUBMETIDO A UM TRATAMENTO TÉRMICO E UM MATERIAL PARTICULADO DE LIGANTE, EM QUE O TRATAMENTO TÉRMICO COMPREENDE O AQUECIMENTO DE UM MATERIAL PARTICULADO CERÂMICO DE 600 A 1200ºC, DURANTE 1 A 20 H, PARA PRODUZIR O MATERIAL PARTICULADO CERÂMICO SUBMETIDO A UM TRATAMENTO TÉRMICO E O MATERIAL PARTICULADO DE LIGANTE É UM COMPOSTO SOLÚVEL EM ÁGUA. MÉTODO PARA MANUFATURA ADITIVA POR IMPRESSÃO POR JATO DE LIGANTE DE UM OBJETO CONFORMADO COMPREENDENDO A REPETIÇÃO DAS ETAPAS DE DEPOSITAR UMA CAMADA DE COMPOSIÇÃO DA INVENÇÃO SOBRE UMA CAMA DE IMPRESSÃO E DEPOSITAR UM LIGANTE LÍQUIDO. A INVENÇÃO RESOLVE OS PROBLEMAS DA FRAGILIDADE MECÂNICA DOS OBJETOS CONFORMADOS POR IMPRESSÃO POR JATO DE LIGANTE E DOS SEUS DEFEITOS DE DESIGN, EM QUE O TRATAMENTO TÉRMICO CRIA LIGAÇÕES E AGREGAÇÕES ENTRE AS PARTÍCULAS DO MATERIAL CERÂMICO, MANTENDO-AS DURANTE A IMPRESSÃO.
Patent RU-94003458-A (RU)
Inventor: SIRITSYN A I
IPC: B23F5/12
Filed: 1994-01-31
Abstract: FIELD: machining of cylindrical wheels with curved teeth. SUBSTANCE: lathe has chisel spindle positioned for rotation by discrete circular feed drive, for reciprocating and rocking by drive, column connected with base, table mounted on base guides for linear movement in parallel with chisel rocking axis and adapted for positioning toothed wheel to be grooved so as to be rotated by discrete circular feed drive and chisel and table program control system. Lathe further has cross-piece disposed on column vertical guides and movable by drive. Cross-piece has horizontal guides and carriage mounted on horizontal guides and provided with longitudinal motion drive and rotary support mounted in carriage. Chisel spindle is built in rotary support, which is connected with rocking motion drive. Lathe program control system has primary carriage and rotary support motion pulse converters mounted respectively on cross-piece and carriage. Rocking motion drive is formed as drive gear mounted on carriage and coupled with tooth gear fixed on rotary support. Such construction allows constant cutting angle throughout chisel stroke to be provided. EFFECT: increased efficiency and wider operational capabilities by machining both inner and outer teeth of any configuration. 2 cl, 4 dwg
Patent RU-94023290-A (RU)
Inventor: JUR EV JU V
IPC: B22F9/06
Filed: 1994-06-17
Abstract: FIELD: production of metal powder; powder metallurgy. SUBSTANCE: metal melt is dispersed through mixing it with powder of solid carrier whose melting point, sublimation temperature and decomposition temperature are considerably higher than melting point of metal being dispersed; then mixture is cooled and powder is separated from carrier. EFFECT: enhanced reliability.
Patent RU-94024976-A (RU)
Inventor: BIKTASHEV F KH
IPC: F16H37/08
Filed: 1994-07-04
Abstract: FIELD: mechanical engineering, mining industry, industrial engineering. SUBSTANCE: variable-speed transmission has common transmissions, normally tree differentials and one reducer, which are connected to automatically provide required torque of output shaft without using special devices. Transmission allows continuously variable transmission ratio within the range of 0 to indefinite value to be provided. EFFECT: wider operational capabilities, increased efficiency, reduced production cost, enhanced reliability in operation, improved running characteristics of vehicles using the transmission. 2 cl, 6 dwg
Patent RU-94025172-A (RU)
Inventor: LESHCHINSKIJ L A
IPC: A61B5/02
Filed: 1994-07-04
Abstract: FIELD: medicine. SUBSTANCE: method involves applying gravitational test at sixth - tenth day from the beginning of the illness and bicycle ergometry after the forty fifth day. Early bicycle ergometry is applied at the eleventh - twentieth day in consequently increasing load power level according to the scheme 12.5 - 25 - 37.5 - 50 W. The bicycle ergometry is carried out at the twentieth - fortieth day after appearing myocardial infarction at the late stage of hospital care. EFFECT: enhanced effectiveness of health control.
Patent RU-94027052-A (RU)
Inventor: FILATOV A T
IPC: A61M21/02
Filed: 1994-07-18
Abstract: FIELD: medicine, narcology. SUBSTANCE: method comprises production of conditioned reaction against alcohol by group suggestive effect followed by conducting individually hypnotic session of stress therapy. To this end, points 88 and 100 of each ear is pecked serially with probe for 2-3 minutes with suggesting, simultaneously, aversion to alcohol in patient. EFFECT: provides stable abstinence to alcohol. 1 cl
Patent RU-94028722-A (RU)
Inventor: SINCHURINA A V
IPC: A61Q19/00
Filed: 1994-08-02
Abstract: FIELD: cosmetics. SUBSTANCE: face cream containing animal and vegetable fats, lanolin, borax, wax, bioactive additions, aromatic principle and water has swine fat as a lipid fraction which is deodorized at 100-105 C, cacao oil and vegetable oil, and also bioactive additions - rose seed oil, oily solutions of vitamin A and vitamin E taken at the following ratio of components, wt. -%: swine fat 9-15; cacao oil 7-20; lanolin 12-25; vegetable oil 30-50; borax 5-10; rose seed oil 8-15; vitamin A oily solution 3-10; vitamin E oily solution 3-10; wax 4-8; aromatic principle 10-12, and water - the rest. EFFECT: enhanced biological effect due to increased repair and stabilization of lipid metabolism.
Patent RU-94031386-A (RU)
Inventor: TREFILOV B B
IPC: A61K39/00
Filed: 1994-08-08
Abstract: FIELD: veterinary virology. SUBSTANCE: living culture of Goosa parvovirus clone 6 at biological activity '10-10ТЦД' is used as an antigen. Invention can be used for production of vaccines for specific prophylaxis and treatment of goose viral enteritis. EFFECT: enhanced effectiveness, harmless, antigenic activity, prolonged storage, simplified preparing.
Patent RU-94040329-A (RU)
Inventor: FEDOROV G D
IPC: B28B3/24
Filed: 1994-11-02
Abstract: FIELD: construction industry. SUBSTANCE: invention relates to equipment for formation of ceramic strip tiles by method of plastic extrusion moulding. Tile forming set has piston press with drive from hydraulic cylinders, rest with transducer of length of article, string cutting tool kinematically coupled to string cutter of tongues. Set is additionally equipped with separable carriages mounted for movement perpendicular to axis of piston press. Working surface of each carriage corresponds to profile of tiles, is lined with antifriction material and the opening for string cutter of tongues. Presence of separable carriages establish conditions for defect-free removal of raw tiles and laying of them on drying mounts, including mechanized handling of tiles. In case of necessity there can be additionally mounted through for tongue, thrust straps bordering on strings (lower one placed under tongue and upper one repeating profile of face surface of tiles), guiding templates to cut angles of tiles. In version for mechanized removed of tiles it will be advantageous to interconnected two carriages and to couple them to hydraulic cylinder. Tile pushers to place them on to drying mounts may be installed at extreme positions of carriages. Straps of pushers can be made according to shape of section of tiles. EFFECT: improved quality of tiles, enhanced productivity of set. 4 dwg
Patent RU-94040466-A (RU)
Inventor: FURSOV V M
IPC: C10L1/20
Filed: 1994-11-04
Abstract: FIELD: additives to internal combustion engine fuels. SUBSTANCE: additive contains 1-3 wt % ferrocene and up to 100 wt % dichloroethane. EFFECT: increased octane number, reduced carbon formation in combustion chamber, stabilized engine operation, reduced carbon monoxide content in exhaust gases.
Patent RU-94043601-A (RU)
Inventor: OSIPOV A F
IPC: B21D19/00
Filed: 1994-12-13
Abstract: FIELD: plastic working of metals, in particular, sheet stamping. SUBSTANCE: method involves two stages: at the first stage local depressions are drawn in the process of beading in maximum deformation-loaded locations; at the second stage openings are punched, with opening beads passing over bottom of drawn depressions, and beads of required shape are formed. In the process of local depression drawing, punching and beading, deformation extent E1 = 0.26, E2 = -0.093, plasticity factor is significant since maximum deformation values during drawing are E1 = 0.405, E2 = -0.093. When mechanical characteristics slightly deviate toward affecting stamping parameters, this deviation will exceed plasticity factor. EFFECT: increased quality and reduced production cost of part. 2 cl, 2 dwg
Patent RU-94045465-A (RU)
Inventor: KRASHENININ P F
IPC: A23C9/20
Filed: 1994-12-28
Abstract: FIELD: dairy-canned industry. SUBSTANCE: product comprises milk, serum proteins, vegetable oil, carbohydrate components, water- and lipo-soluble vitamins, mineral substances, food albumin, medical plants, wheat middlings, color. EFFECT: balance of products composition provided efficient alimentation and hypogalaxy prophylaxis of pregnant women and nursing mothers.
Patent RU-94046442-A (RU)
Inventor: LINDEBERG JAN-INGE
IPC: E04C2/04
Filed: 1993-06-02
Abstract: FIELD: article of stone. SUBSTANCE: article of stone (1) made in the form of a plate is suitable for indoor and outdoor facing, in particular, facade facing etc. Article (1) of stone is impregnated with an impregnant (3) to improve its strength and flexibility through filling porous (4), cracks and other cavities. EFFECT: high strength. 2 dwg
Patent RU-95101325-A (RU)
Inventor: ZHURAVLEV O A
IPC: H01S3/02
Filed: 1995-01-31
Abstract: FIELD: production of lengthy quasi-steady plasma electrodes in slotted discharge chambers of gaseous-discharge power lasers that do not require fast pumping of working mixture. SUBSTANCE: electromechanical device for exciting homogeneous surface discharge in high-density gases is assembled on insulating substrate of movable electrode (rotor) made in the form of grounded cylinder or casing with high-resistance insulating film on external surface. Homogeneous surface discharge is excited by film between lengthy high-voltage and current-collecting knife electrodes mounted on same plane along generating line of movable electrode with minimal gap relative to substrate surface. Working gap L between electrodes is chosen from condition $$$, where U is voltage across high-voltage electrode; $$$ is tabulated value of reduced breakdown electric field strength for given gas; P is gas medium pressure. EFFECT: improved design. 2 dwg
Patent RU-95102063-A (RU)
Inventor: MAMAEV G V
IPC: A61M5/00
Filed: 1995-02-10
Abstract: FIELD: medicine. SUBSTANCE: parent sterile infusion solution is passed through milliporous diaphragms between of that dry dosed sodium hydrocarbonic powder is placed and solution is administrated in patient organism simultaneously. Device is made as drop-chamber where two milliporous diaphragms were built in and dry sterile dosed sodium hydrocarbonic powder is placed between these diaphragms. Diaphragms were fixed by two fixing plastic rings inserting one into other. Invention can be used for normalization of blood acid-alkaline state, in part, acidosis by intravenous administration of sodium hydrocarbonate. EFFECT: simplified technology, improved method of preparing.
Patent RU-95103332-A (RU)
Inventor: STEPANOV V G
IPC: C22B43/00
Filed: 1995-03-10
Abstract: FIELD: utilization of harmful production wastes, demercurization of failed LUMINESCENT lamps containing metal mercury. SUBSTANCE: device for thermal demercurization of LUMINESCENT lamps consists of chamber with heater, appliance for opening the lamps, container for mercury vapor collection connected with vacuum pump, low temperature vacuum trap for mercury condensation. Novelty consists in that the internal space of low-temperature vacuum trap is communicated with internal space of container for collection of mercury vapors whose upper cover has sockets for installation of LUMINESCENT lamps and provided with cutting appliance, for instance, electrical spiral or cutting head for cutting lamp body. Opened lamps in vacuum are heated up to 85-100 C, mercury is evaporated from the opened end of lamp and them, condensed in low- temperature trap at temperature of minus 190 C. Concentration of mercury vapors in container is monitored by concentration transducer, and upon attainment of the permissible level, the process is completed, mercury is poured off the low-temperature vacuum trap. EFFECT: lamps may be used repeatedly for its designated purpose or for some other purposes.
Patent RU-95104214-A (RU)
Inventor: TAKASI FUDZITA
IPC: C07D277/06
Filed: 1995-03-23
Abstract: FIELD: organic chemistry. SUBSTANCE: invention describes compounds of the formula (I): $$$ where: $$$ and $$$ each means hydrogen or alkyl; or $$$ and $$$ taken together form the group of the formula $$$ where k - the whole number; $$$ means hydrogen, alkyl, alkoxy, halogen or hydroxy; A and B each means hydrogen, alkyl, aralkyl, aliphatic carboxylic acyl, aryl-substituted aliphatic carboxylic acyl, aromatic carboxylic acyl or carbamoyl; or A and B taken together form groups: $$$, -C(=O)-C(=O)-, $$$ or $$$; X means group of the formula $$$ where W is aryl or heterocyclic group; $$$ is a simple bond, oxygen or sulfur or $$$ where $$$ means hydrogen, alkyl, aralkyl or aryl and m = 0 or the whole number; Y means group of the formula $$$ where $$$ is a simple bond, oxygen or sulfur and n - the whole number; Z means heterocycle, and their salts, esters, solvates and prodrug precursors that can be used for treatment and/or prophylaxis, for example, hyperlipemia, hypoglycemia, obesity, insufficient tolerance to glucose, insulin-resistance and diabetic complications. EFFECT: improved method of synthesis, enhanced effectiveness.