Patent SG-11201805381T-A (SG)
Title: Electroporation device with detachable needle array with lock-out system
Inventor: STADELMANN BEAT
IPC: A61N1/32
Filed: 2016-12-30
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 6 July 2017 (06.07.2017) WIPOIPCT (10) International Publication Number WO 2017/117508 A1 (51) International Patent Classification: A61N1/18 (2006.01) A61N1/04 (2006.01) A61N1/32 (2006.01) A61N1/00 (2006.01) A61F 7/00 (2006.01) A61B 18/14 (2006.01) A61B 17/34 (2006.01) A61M 37/00 (2006.01) (21) International Application Number: PCT/US2016/069438 (22) International Filing Date: (25) Filing Language: (26) Publication Language: 30 December 2016 (30.12.2016) English English (30) Priority Data: 62/272,758 30 December 2015 (30.12.2015) US (71) Applicant: INOVIO PHARMACEUTICALS, INC. [US/US]; 660 W. Germantown Pike, Suite 110, Plymouth Meeting, PA 19462 (US). (72) Inventors; and (71) Applicants CAMPILLO-AGUSTI, Alejandro [US/US]; C/o Inovio Pharmaceuticals, Inc., 660 W. Ger­ mantown Pike, Suite 110, Plymouth Meeting, PA 19462 (US). HO, Eduardo, E. [US/US]; C/o Inovio Pharmaceut­ icals, Inc., 660 W. Germantown Pike, Suite 110, Plymouth Meeting, PA 19462 (US). LOVELL, Nathan [US/US]; C/o Inovio Pharmaceuticals, Inc., 660 W. Germantoen Pike, Suite 110, Plymouth Meeting, PA 19462 (US). MASTERSON, Steven [US/US]; C/o Inovio Pharmaceut­ icals, Inc., 660 W. Germantown Pike, Suite 110, Pylmouth Meeting, PA 19462 (US). (72) Inventors: STADELMANN, Beat; C/o Inovio Pharma­ ceuticals, Inc., 660 W. Germantown Pike, Suite 110, Ply­ mouth Meeting, PA 19462 (US). KEMMERRER, Steph­ en; C/o Inovio Pharmaceuticals, Inc., 660 W. Germantown Puke, Suite 110, Plymouth Meeting, PA 19462 (US). (74) Agent: HOFMEISTER, Todd, S.; Michael Best & Friedrich LLP, 100 East Wisconsin Avenue, Suite 3300, Milwaukee, WI 53202 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, [Continued on next page] (54) Title: ELECTROPORATION DEVICE WITH DETACHABLE NEEDLE ARRAY WITH LOCK-OUT SYSTEM 00 o i> (57) : An electroporation device with a needle array removably attached thereto, the needle array having a body, a shroud movable with respect to the body between a rest position and one or more actuated positions, and an auto-lock assembly. Where the auto-lock assembly is adjustable between a locked configuration, where the shroud is not mov­ able with respect to the body, and an unlocked con­ figuration, where the shroud is movable with respect to the body, and where biasing the shroud from the rest position to the one or more actuated positions and back to the rest position adjusts the auto-lock from the unlocked configuration to the locked con­ figuration. FIG. 3 o CJ o £ wo 2017/117508 AI III llll IIII III Hill III III III III lllll 111 lllll 111 Hill 111 lllllll llll 111 llll TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)-. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))