baber/WOPTO huggingface dataset:
Patent DE-69108738-T2 (DE)
Inventor: SCHALLY ANDREW
IPC: A61K38/08
Filed: 1991-11-15
Granted: 1995-08-17
Abstract: The novel pseudo polypeptides of this invention are potent bombesin antagonists. There are provided processes for their production, pharmaceutical compositions comprising said polypeptides and their use as pharmaceutically active agents. More particularly the present invention provides pseudopeptides comprising a nonapeptide moiety of formula I: X-A1-A2-A3-A4-A5-A6-A7-A8-psi-A9-Q wherein Q is NH2 or OQ1 where Q1 is hydrogen, C1-10 alkyl, phenyl or phenyl-C7-10alkyl; X is hydrogen or a single bond linking to A2 the acyl residue of an organic acid, or a group of formula R1CO- wherein (1) R1 is hydrogen, C1-10 alkyl, phenyl or phenyl-C7-10-alkyl; (2) R1CO- is (a) R2N(R3)-CO- wherein R2 is hydrogen, C1-10alkyl, phenyl or C7-10phenyl-C7-10-alkyl, R3 is hydrogen or C1-10alkyl; (b) R4-O-CO- wherein R4 is C1-10alkyl, phenyl or phenyl-C7-10-alkyl. A1 is D-, L- or DL- pGlu,, Nal, Phe, Thl, Tyr, Tpi, Hca, Hpp, Mpp, Trp or Trp substituted in the benzene ring by one or more members selected from the group consisting of halogen, NO2, NH2, OH, C1-3 alkyl and C1-3 alkoxy wherein halogen is fluorine, chlorine and bromine; wherein A2-A7 and A9 are each amino acid residues; A8 is a reduced isostere of Leu or Phe.
Patent DE-69121492-T2 (DE)
Inventor: YOUNG NIELS
IPC: F16D3/18
Filed: 1991-02-19
Granted: 1997-03-13
Abstract: A gearing system includes a pair of gear support plates arranged to rotate about parallel but offset axes with the plates extending parallel to each other in parallel radially extending plates. Each plate includes axially extending teeth in the form of sections of lune shaped elements having concave and convex opposed surfaces. The teeth are interdigited axially such that various pairs of interdigited teeth will be in cooperating surface contact. Rotation of each support plate about its own axis causes the teeth to orbit relative to each other and engage in a driving relationship in a smooth manner, with the convex portion of certain teeth engaging smoothly with the concave portion of adjacent teeth. The gearing system provides a 1:1 speed ratio and has application as an Oldham coupling or synchronizer for a scroll fluid device.
Patent DE-69129655-T2 (DE)
Inventor: SRAMEK JOHN
IPC: C08L33/02
Filed: 1991-01-11
Granted: 1999-01-21
Abstract: The present invention relates to an aerosol hair spray package having reduced volatile organic compound emission during the useful life of the package. A hair spray composition (3, 25) is packaged in either a self-propelled aersol hair spray package (1) or a pump spray hair spray package (20) containing a low delivery rate discharge means (6,23). The hair spray composition (3, 25) contains a combination of at least two polymers in weight ratios of 99:1 to 1:99 differing in weight average molecular weight by at least 1.5, one of which is required to have a number average molecular weight of at least 100,000. This blend of polymers combines with the low delivery rate discharge means-0.2-0.38 grams per second for the self-propelled hair spray package (1) and 0.06 to 0.012 grams per pump stroke for the pump spray hair spray package (20)-to provide an atomized hair spray composition having a volume mean particle size of 60+/-12 microns for package (12) and 73+/-13 microns for package (20). These packages are considerably smaller in size than conventional hair spray packages having higher discharge rates, but provide substantially the same number of uses per container as the larger size conventional hair spray packages, thus effecting reduced cost and environmental impact advantages.
Patent DE-69200835-T2 (DE)
Inventor: DORIGO ODDINO
IPC: B08B3/04
Filed: 1992-02-24
Granted: 1995-07-06
Abstract: Machine for the continuous treatment by means of liquids of small objects fed in bulk, comprising a substantially horizontal rotating container (1) formed of a plurality of coaxial elements (2, 13) positioned tail-to-head, inclined vanes (3) projecting from the inner walls of said elements (2, 13) for the mechanical advancement of the objects (10) being treated, and said elements (2, 13) being reciprocally connected with the interposition of gaps (4, 14) to discharge the treatment liquids; fixed pipelines (5) run along the inside of said container (1) and are provided with nozzles (6) to spray the liquids onto said objects (10). <IMAGE>
Patent DE-69207861-T2 (DE)
Inventor: BONO FRANCESCO
IPC: B62M1/00
Filed: 1992-03-25
Granted: 1996-05-30
Abstract: Mechanism to temporarily convert the front wheel of bicycles into a driving wheel, comprising a lever (5) hinged in front of and on top of the frame; the handle-bar -E- is fixed to said lever together with a catch (14), with a mobile stopping tooth which cooperates with stopping means (11, 15) attached to the steering column (10), to block/release the handle-bar which can be swung on a vertical plane; transmission organs, comprising a chain (7) which engages a free wheel (8) coaxial and fixed to the front wheel -I-, transmit the alternate movement given to the handle-bar to the said free wheel; elastic return means for returning to the original position of the handle-bar are also provided. Control means (16, 17) for the stopping tooth of the catch (14) are applied to the handle-bar. <IMAGE>
Patent DE-69208841-T2 (DE)
Inventor: DE JONG JOHANNES
IPC: B66B11/02
Filed: 1992-12-14
Granted: 1996-09-05
Abstract: Guide seat for an elevator car, which supports a guide moving along a guide rail (6). The guide seat comprises a fixing part (16) by which the guide seat is attached to the car structure (2), and a base plate (12,26,33) on which a guide structure is mounted. To pass the forces between the guide rail (6) and the elevator car (1), the guide seat is provided with at least one insulator (17,27,32) made of an elastic material, such as rubber, said insulator being placed between the fixing part and the base plate. <IMAGE>
Patent DE-69214460-T2 (DE)
Inventor: ELK SVEND
IPC: B05B11/06
Filed: 1992-12-10
Granted: 1997-04-03
Abstract: A dispenser for dispensing a dosage or a powdery or fluid drug from a cartridge having a tubular chamber the ends of which are sealed by breakable membranes. The dispenser comprises a housing forming a cylinder which is at one end closed by an end wall through which an outlet pipe communicates with the interior of the cylinder. The other end of the cylinder is closed by a plunger which may be displaced into the cylinder. The drug cartridge is placed in a piston mounted axially displaceable in the cylinder between the end wall and the plunger, and the tubular chamber extends from one side of the piston to the other. Penetrators for breaking the membranes are provided at the inner end of the outlet pipe and the inner end of the plunger.
Patent DE-69221120-T2 (DE)
Inventor: VIRET JEAN-FRANCOIS
IPC: C07K14/245
Filed: 1992-04-10
Granted: 1998-02-26
Abstract: The present invention relates to recombinant live attenuated bacterial strains expressing O-serotype determinants of gram-negative enteric pathogens in a form covalently bound to a lipopolysaccharide (LPS) core, wherein the resulting LPS molecules are essentially indistinguishable from the ones present in the original pathogenic strains. Such recombinant carrier strains may be used as live vaccines for oral immunization against e.g. bacillary dysentery caused by virulent strains of Shigella spp.
Patent DE-69226252-T2 (DE)
Inventor: LAZARCHIK DANIEL
IPC: B26B21/22
Filed: 1992-05-14
Granted: 1999-02-18
Abstract: A combination razor handle and blade dispenser cover are provided, the razor handle assembly (10) comprising a grip portion formed of a pair of shells (14, 16) mounted on opposite sides of a substantially flat planar body member (12). The pair of shells (14, 16) extend downwardly at an angle beyond one end of the planar body member (12) and form a housing containing operative structure responsive to a pair of opposed buttons (30, 31) extending outwardly from the housing sides to provide attachment of a razor blade assembly onto the handle. The cover (10) for retaining a dispenser containing a plurality of safety razor blade cartridges is employed with the razor which has a hand or finger gripping portion with a concave surface (108) provided with a plurality of sinuous recesses (106) formed therein. The dispenser cover (110) is comprised of wall structure forming a substantially rectangular cavity (116) for receiving and retaining a blade cartridge dispenser and one wall comprises an outer surface (132) having a convex shape for mating engagement with the razor concave surface (108). A pair of sinuous outwardly projecting ribs (134, 136) for interfitting engagement with a selected pair of recesses (106) on the razor gripping portion is disposed on the convex surface (132) of the dispenser cover (110) and serves to locate and retain the razor, dispenser cover combination as a unit for packaging and storage of the razor when not in use.
Patent DE-69233552-T2 (DE)
Inventor: GILHOUSEN S
IPC: H04J13/00
Filed: 1992-05-17
Granted: 2006-07-13
Abstract: A cellular communication system in which a system user and another user communicate with each other by way of information carrying spread spectrum modulated signals transmitted via a cell-site in which system: the system user comprises a transmitter for transmitting information carrying spread spectrum modulated signals to said cell-site, a receiver for receiving information carrying spread spectrum modulated signals from said cell-site and means for measuring signal quality in said information carrying spread spectrum modulated signals received by the system user; the cell-site comprises a transmitter for transmitting information carrying spread spectrum modulated signals to said system user, a receiver for receiving information carrying spread spectrum modulated signals from said system user and adjusting means for adjusting the power of information carrying spread spectrum modulated signals transmitted from the cell-site ; ; and power control means is provided for controlling the transmission power of the information carrying spread spectrum modulated signals by measuring the signal power in the information carrying spread spectrum modulated signals received by the system user and transmitting data representing the measured power to the cell-site by way of the information carrying spread spectrum modulated signals, the adjusting means being responsive to the data in the information carrying spread spectrum modulated signals from the system user to adjust the power in the information carrying spread spectrum modulated signals transmitted by the cell-site.
Patent DE-69301467-T2 (DE)
Inventor: LAMBERT JOHN
IPC: F02B65/00
Filed: 1993-06-24
Granted: 1996-10-02
Abstract: A small bore internal combustion engine our-stroke operating cycle which is adapted to function with natural gas and other gaseous fuels and which is particularly useful with residential heat pump assemblies with maximum life expectancy, high thermal efficiency, and low exhaust gas emissions, wherein provision is made for assembling the engine in a compact heat pump system with a low operating noise level and an extended engine maintenance interval.
Patent DE-69319375-T2 (DE)
Inventor: BARBERA ALACREU JOSE VICENTE
IPC: A61F2/00
Filed: 1993-04-23
Granted: 1998-12-17
Abstract: The tumour-affected vertebra is removed and the prosthesis (2) is inserted in the closed position, with the minimum height thereof. Thereafter it is opened up until a sufficient height is obtained to restore the anatomical continuity of the column to make it capable of supporting the load and allow mobility of the patient. The prosthesis is made of steel and comprises three parts, a centre part (4) and an upper and a lower platform (5) and (6) which are moveable in opposite directions to extend the height of the assembly, until they bite into the body of the neighbouring vertebra. The invention is applicable in surgery of malignant tumours of the dorsal and lumbar portions of the spinal column. <IMAGE>   <IMAGE>
Patent DE-69322863-T2 (DE)
Inventor: ABREKTSSON BJOERN
IPC: A61B17/86
Filed: 1993-05-14
Granted: 1999-07-01
Abstract: The invention relates to a prosthesis for uni-condylar or bi-condylar replacement of a joint in a human body and in particular to the tibia side of a knee joint. By means of an elongate fixture, a prosthetic plate is secured in position in a pre-prepared tibia portion and is allowed to heal, without further surgery being required. The invention also relates to a device for preparing the knee joint for prosthetic reception.
Patent DE-69323918-T2 (DE)
Inventor: BORTAS MATS OLA
IPC: H01B7/17
Filed: 1993-01-08
Granted: 1999-07-29
Abstract: The present invention relates to an electric cable which includes at least one cable part and at least one shield which surrounds at least one cable part, and which further includes a plastic or a rubber sheath which embraces the cable part or parts and the shield, wherein each cable part includes a conductor made of copper wire or some other electrically conductive material, and a plastic or a rubber insulating layer. According to the invention, the shield (4) is comprised of one or more prefabricated, woven or braided bands which are placed longitudinally around the cable part or parts (1). The total width of the shield band or bands (4) is roughly equally as large as the perimeter of the underlying construction.
Patent DE-69329985-T2 (DE)
Inventor: PAWELSKI ROBERT LEE
IPC: H04Q11/04
Filed: 1993-10-13
Granted: 2001-09-20
Abstract: A time-division multiplex switch (100) switches a hierarchy of data rates. It sets up higher-rate connections not as a plurality of individual lowest-rate connections but as one or more time slots in each one of a plurality of sequential frames (40, 50) that correspond to that higher rate in each superframe (30). A time-slot-interchange switching element (131, 141) of the switch utilizes a plurality of physically or logically distinct double-buffered data memories (301,302, 303) each corresponding to a different one of the superframe and different-size ones of the frames. Reading and writing of each of the data memories' buffers alternates with the corresponding one of the superframe and different-size frames; reading of a data memory's buffer immediately follows writing of that buffer. Information from all incoming time slots is written into each one of the data memories, but only information corresponding to the data rate of an individual data memory's corresponding frame size is read from that data memory into outgoing time slots. A control memory (305) maps memory locations of the data memories to output time slots. A corresponding control architecture in a switching element (1700) of a time-multiplexed switch (120) uses a control memory (1701) that maps input ports to time slots of an output port. <IMAGE>
Patent DE-69406407-T2 (DE)
Inventor: HASLER RUDOLF
IPC: H02J7/10
Filed: 1994-07-04
Granted: 1998-04-09
Abstract: A circuit arrangement for charging batteries comprises a charging current source for supplying charging current pulse trains. The circuit arrangement comprises a first detection device for determining an actual voltage dependent upon a variable reference voltage, which actual voltage is proportional to the average sum voltage of a battery. The first detection device supplies a detection signal corresponding to the detection result and which controls the duty cycle of the pulse-shaped control signal which can be generated by a control pulse generator. The control pulse generator varies the duty cycle dependent on the detection signal when the actual voltage increases or the reference voltage decreases, in a manner such that the ratio between the charging period and the charging pause in a charging pulse train is reduced. A device is provided which enable the reference voltage to be varied in the same sense as the duty cycle depending on this duty cycle.
Patent DE-69414395-T2 (DE)
Inventor: COLOMBO DANIEL
IPC: E06B3/30
Filed: 1994-08-04
Granted: 1999-06-17
Abstract: A method for forming shaped members by drilling, milling or pushing. The positions of tools are preset with respect to at least one reference surface of the machine. A reference surface of each of the members to be machined is placed on the machine reference surface. The tools are moved in union relative to the member on the machine so that at least one tool in the set can carry out a machining step on at least one side wall of the member. The tools are preset and the member is shaped in such a way that members of various cross sections may be suitably machined from the same set of tools.
Patent DE-69415955-T2 (DE)
Inventor: TOCCHET IVAN
IPC: A23L5/10
Filed: 1994-07-21
Granted: 1999-05-27
Abstract: PCT No. PCT/EP94/02406 Sec. 371 Date Mar. 16, 1995 Sec. 102(e) Date Mar. 16, 1995 PCT Filed Jul. 21, 1994 PCT Pub. No. WO95/04334 PCT Pub. Date Feb. 9, 1995Food vending machine particularly for warm food, toasts in the specific case, including multiple per se known stations which are combined so as to obtain a machine which starts from a blister-packaged container inside which a pre-packaged uncooked toast is wrapped and transfers said toast by means of an appropriate drive to a pickup station so that the product to be cooked is placed at a moving cooking station and so that the product is extracted with special extractors after cooking so as to offer it, at the end of the cycle, completely wrapped in an appropriate hygienic napkin for taking on the part of the consumer.
Patent DE-69421280-T2 (DE)
Inventor: DAUNTER BRIAN
IPC: A61K31/40
Filed: 1994-06-24
Granted: 2000-07-13
Abstract: A method for the treatment of an inflammatory complaint including the step of administration of a compound of general formulae (I to XII) described herein in figure or mixtures thereof to a subject suffering from said inflammatory complaint. There is also included a therapeutic agent for relief of inflammatory complaints which includes a compound of general formulae (I to XII) as described in figure or mixtures thereof in combination with an appropriate filler which is preferably dicalcium phosphate. The invention also includes within its scope plant extracts which may contain one or more of the above-mentioned compounds and in particular plant extracts of the genus Umbelliferae, celery (Apium graveolens), parsley (Petroselimun hortense) and dill (Anethum graveolens). It is believed that compounds of the above-mentioned formulae and in particular butylphthalide, sedanenolide and sedanolide (in both cis and trans forms otherwise known as essential oils which are mainly derived from plants) mimic the physiological response of essential fatty acids and also their prostaglandin analogues.
Patent DE-69422050-T2 (DE)
Inventor: LENTSCH STEVEN
IPC: C11D1/94
Filed: 1994-08-04
Granted: 2000-08-31
Abstract: Spray-on cleaners that can be delivered by pump or pressurized gas aerosol spray head have been known to cause respiratory distress in the form of a chocking mist. The chocking mist associated with aerosol use can be reduced or eliminated by formulating surface cleaning compositions that can be dispensed through a spray head resulting in an aerosol or mist droplet having a mean particle size greater than about 200  mu m. We have found that typical spray-on cleaners have a mean particle size less than about 175  mu m and, depending on the concentration and degree of irritation of strong base or strong acid components, can cause severe respiratory distress. Preferred thickeners have been found for use in the non-chocking aerosol or mist compositions.
Patent DE-69426527-T2 (DE)
Inventor: FRENKEN LEON GERARDUS JOSEPH
IPC: C12R1/685
Filed: 1994-06-09
Granted: 2001-08-30
Abstract: The present invention provides a process for producing fusion proteins comprising ScFv fragments by a transformed Aspergillus mould containing a DNA sequence encoding the ScFV fragment under control of at least one expression and/or secretion regulating region derived from a mould selected from the group consisting of promoter sequences, terminator sequences and signal sequence-encoding DNA sequences or functional derivatives or analogues thereof. Such regulating region can be derived from the endoxylanase II gene (exlA gene) of Aspergillus niger var. awamori present on plasmid pAW14B or can be the combination of both a promoter and a signal sequence-encoding DNA sequence derived from a glucoamylase gene ex Aspergillus plus a terminator sequence of a trpC gene ex Aspergillus. Preferably a fusion protein comprising "secreted mould protein - (KEX2 -) ScFv" is produced. Also provided are new products comprising an ScFv fragment or fusion product thereof, compositions, e.g. consumer products, containing both old and new products so produced. Preferably the ScFv fragment recognizes a compound present in the human eco-system, such as microorganisms or enzymes. Such compounds can be present in the oral cavity, e.g. involved in the formation of plaque, caries, gingivitis, periodontal diseases, or bad breath, or on the human skin, e.g. involved in the formation of malodour, inflammation or hair loss, or can be a hormone, e.g. HCG.
Patent DE-69433427-T2 (DE)
Inventor: WEI AI-PING
IPC: C07K14/59
Filed: 1994-06-01
Granted: 2004-09-16
Abstract: An improved oligopeptide composition for use in a fluorescent polarization immunoassay for a high molecular weight analyte is disclosed, along with a kit and a method using the composition. The composition comprises an oligopeptide selected by a screening procedure in which a plurality of different oligopeptides having respective amino acid sequences that represent sequential overlapping segments of the analyte amino acid sequence, and a fluorescent label bound thereto. The screening process further includes screening to select a composition which exhibits fluorescence enhancement upon binding the analyte. A preferred embodiment of the oligopeptide is one having an amino acid sequence which does not form internal disulfide bridges. Such a preferred oligopeptide will generally have no more than one cysteine residue. In a further preferred embodiment, the fluorescent label is tetramethylrhodamine or a cyanine dye. The kit may be packaged with instructions directing a user to prepare an assay solution containing the monoclonal antibody and the oligopeptide in certain respective concentrations. The composition, method and kit are constructed to detect nanomolar concentrations of the analyte.
Patent DE-69515646-T2 (DE)
Inventor: VERCRUYSSE MICHEL
IPC: G01N21/89
Filed: 1995-05-10
Granted: 2000-08-17
Abstract: The present invention concerns a method and an apparatus for detecting flaws in moving fabrics or the like. Method for detecting flaws on moving fabrics, cloths, sheet materials or the like, comprising the steps of forming an image of the fabric or the like and recording the said image by at least one array light sensitive sensor, digitizing the resulting video signal, transmitting the digitized image, after correction and specific modeling, to several distinct detection channels working contemporaneously, each of them being dedicated to one type or category of flaws to be detected, splitting, for each channel, the said modelised image into vectorial edge elements representative of the local concerned flaw texture, reconstructing, for each channel, the flaw type being searched on the basis of the said edge elements and using adapted windows, evaluating the weight components of all the edge elements contained in each said windows and indicating at least, if the case occurs, the presence, the type and/or the position of the flaws possibly detected. <IMAGE>