baber/WOPTO huggingface dataset:
Patent AU-2020203792-A1 (AU)
Title: Compositions For Linking DNA-Binding Domains And Cleavage Domains
Inventor: PASCHON DAVID
IPC: C12N9/16
Filed: 2020-06-09
Abstract: Disclosed herein are compositions for linking DNA-binding domains and cleavage domains to form 
nucleases, for example nucleases with altered target site separation (gap) preferences as compared 
to conventional linkers. Also described are fusion proteins comprising these linkers. The disclosure 
also provides methods of using these fusion proteins and compositions thereof for targeted cleavage 
of cellular chromatin in a region of interest and/or homologous recombination at a predetermined 
region of interest in cells. Thus, in one aspect, described herein are amino acid sequences linking a 
DNA-binding domain to a cleavage domain. The linker may replace one or more residues of the 
DNA-binding domain and/or cleavage domain.
Patent AU-2020205960-A1 (AU)
Title: Anthelmintic laboratory animal model for heartworm
Inventor: MILLS BRIAN JOHN
IPC: A61K49/00
Filed: 2020-01-07
Abstract: The current invention describes a laboratory animal model for dirofilarial nematodes wherein said laboratory animal is fed a dietary admixture of laboratory feed containing an immunosuppressing agent, for example, a glucocorticoid. The invention also describes the use of the laboratory animal model for screening endoparasiticides for the treatment and/or prevention of filarial nematode infections in animals.
Patent AU-2020213565-A1 (AU)
Title: Anti-CD79B antibody, antigen-binding fragment thereof, and pharmaceutical use thereof
Inventor: YANG CUIQING
IPC: C07K16/28
Filed: 2020-01-22
Abstract: The present invention relates to an anti-CD79B antibody, an antigen-binding fragment thereof, and a pharmaceutical use thereof. Furthermore, the present invention relates to a chimeric antibody and a humanized antibody comprising a CDR region of the anti-CD79B antibody, a pharmaceutical composition comprising the anti-CD79B antibody or the antigen-binding fragment thereof, and a use thereof as an anti-cancer drug. Particularly, the present invention relates to a humanized anti-CD79B antibody, and a use thereof in preparation of a drug for treating lymphoma (such as DLBCL).
Patent AU-2020232441-A1 (AU)
Title: Genome-edited birds
Inventor: CINNAMON YUVAL
IPC: C12N15/85
Filed: 2020-03-03
Abstract: The present disclosure provides exogenous polynucleotide cassettes for generating chimeric bird cells and chimeric birds. The polynucleotide cassettes can be used to produce conditionally-lethal phenotype in male bird embryos. In one embodiment, the present disclosure provides methods for destroying male chick embryos
Patent AU-2020244425-A1 (AU)
Title: In-tank illumination system and method
Inventor: HARMON ANDREW W
IPC: G01F23/00
Filed: 2020-09-29
Abstract: An in-tank illumination system and method for a translucent tank with sensors 
configured to monitor conditions of the tank and material inside. The illumination 
system includes an illumination source that illuminates the tank interior and is visible 
outside; and a controller that determines tank conditions based on the sensor readings, 
and sends control signals to the illumination source. When the controller detects a tank 
condition, it sends control signals to the source to illuminate the tank to indicate the tank 
condition. The system can include a bracket connecting the source to the tank interior 
near the top. The controller and source can be on different vehicles. Different control 
signals can change colors, blink patterns, and other properties of the source to indicate 
different tank conditions. The tank conditions can have different priorities to select 
which to indicate. The severity or duration of tank conditions can also be indicated.  
18
700 
730 732 734 736 738 
Bin Level Tank Tank Scale Meter Motor 
Sensor Pssue Weight Mtr Sensor Sonsor Sensor 
Controller 110 
740 742 744 746 
Red Light W~hite L ig ht Blnkn Othe 
Indication Indication Ambe Colternn 
Illumination 
720 Source 
FIG. 7
Patent AU-2020250205-A1 (AU)
Title: Characterizing data sources in a data storage system
Inventor: ANDERSON ARLEN
IPC: G06F16/28
Filed: 2020-10-07
Abstract: A method for data characterization comprising receiving multiple data sets from one or more 
data sources, generating for each of the received multiple data sets a data profile including 
summary information representative of data characteristics for the corresponding data set, 
applying multiple characterization procedures to at least some of the generated data profiles for 
the multiple data sets to produce characterizations of relationships between fields of records 
corresponding to at least some of the multiple data sets, identifying a candidate set of potentially 
matching data sets from the multiple data sets, including eliminating at least some data sets from 
the multiple data sets, according to the characterizations of the relationships produced by 
applying the multiple characterization procedures to form the candidate set of potentially 
matching data sets, and deriving data quality metrics for the candidate set of potentially matching 
data sets.
Patent AU-2020250662-A1 (AU)
Title: Ornamental sheet, ornamental material, and resin composition
Inventor: GOTO OSAMU
IPC: C08J7/04
Filed: 2020-03-30
Abstract: Provided is an ornamental sheet that can finely, at an extreme level, maintain long term weather resistance and bleed-out suppression. This ornamental sheet at least has a base material layer and a surface protection layer, and contains a hydroxyphenyl triazine compound represented by general formula (I) in any of the layers of the ornamental sheet.
Patent AU-2020260992-A1 (AU)
Title: Loudspeaker system, method and apparatus for absorbing loudspeaker acoustic resonances
Inventor: ORTH SCOTT
IPC: H05K5/00
Filed: 2020-04-21
Abstract: A loudspeaker system (700 or 800) and method for tuning ported loudspeakers and reducing unwanted acoustic resonances provides reduced port noise, eliminates undesired port resonances and improves the accuracy and fidelity of reproduced sound in a loudspeaker system of relatively high efficiency with an enclosure including an Eigen Tone Filter structure ("ETF") comprising a pipe or set of pipes 720, 820 placed inside a loudspeaker vent to absorb the "open pipe" acoustic resonance of the vent. The open-pipe resonance is unwanted and interferes with the midrange performance of the loudspeaker, when in use, if not corrected.
Patent AU-2020268418-A1 (AU)
Title: Utility box and crankbait storage system
Inventor: MCCUNE CLARK
IPC: B65D81/26
Filed: 2020-05-08
Abstract: A utility box or storage system that includes one or more configurable storage compartments. The utility box or storage system can comprise a compartment having a first wall that includes a guide and a second wall, and a plurality of storage units, including at least one of the plurality of storage units that implants into the compartment between the first wall and the second wall. The at least one storage unit can include a ridge that aligns with the guide. The guide can engage the ridge to guide the storage unit during implantation.
Patent AU-2020294526-A1 (AU)
Title: Bending tools and methods of use thereof
Inventor: Fu Rick
IPC: A61B17/06
Filed: 2020-06-02
Abstract: A single-patient-use disposable tool comprises a molded, single-piece body (102) with a curved upper surface (116) having a predetermined bend radius for bending a needle slidably disposed in a sheath. A distal end of the curved surface has a slot (124) for insertion of a tip of a needle, while the proximal end of the curved surface has a guide member (122) for slidably receiving the sheath. Two finger loops (114) or similar ergonomic features allow the user to rotate the bending tool relative to the sheath to bend the needle about the predetermined bend radius. After completing the bend, the tool is removed from the needle and disposed of.
Patent AU-2020314375-A1 (AU)
Title: Lateral propulsion systems and architectures for high altitude balloons
Inventor: GAGNE JACQUES
IPC: H02S10/40
Filed: 2020-05-29
Abstract: Aspects of the technology relate to propulsion systems for high altitude, long duration balloons, such as balloons that operate in the stratosphere for weeks, months or longer. A propeller assembly is used to provide lateral directional adjustments, which allows the balloon to spend more time over a desired region, reduce the return time to the desired region, reduce fleet overprovisioning, and increases the safety case by additional controls and avoidance abilities. A control assembly manages operation of the propeller assembly, including setting the pointing direction, speed of rotation and determining when to turn on the propeller and for how long. The propulsion system including the control and propeller assemblies is rotatable around a connection member of the balloon. Such rotation is independently adjustable from any rotation of the balloon's payload. The propeller blades may be made of plastic, which reduces weight and cost while providing sufficient speed at stratospheric altitudes.
Patent AU-2020322107-A1 (AU)
Title: A method of eliciting an immune response by administering a population of polymersomes having an associated antigen together with a population of polymersomes having an associated adjuvant as well as compositions comprising the two populations of polymersomes
Inventor: NALLANI MADHAVAN
IPC: A61K31/74
Filed: 2020-08-03
Abstract: The present invention relates to a method of eliciting an immune response in a subject by administration of an antigen and an adjuvant, wherein the antigen is associated with a first population of polymersomes, and wherein the adjuvant is associated with a second population of polymersomes, and wherein the two populations of polymersomes are administered to the subject. The present invention also relates to compositions such as vaccines comprising the two polymersome populations of the present invention, methods of eliciting an immune response or methods for treatment, amelioration, prophylaxis or diagnostics of a cancer, autoimmune or infectious disease, comprising providing polymersomes of the present invention.
Patent AU-2020335076-A1 (AU)
Title: PRM-accessible aircraft lavatory
Inventor: CLUCAS DANIEL WILLIAM
IPC: B64D11/02
Filed: 2020-08-19
Abstract: An accessible lavatory unit (103) for an aircraft cabin (102) is disclosed. The lavatory unit (103) is configurable between an able-bodied configuration and a PRM-accessible configuration. In the able-bodied configuration the lavatory unit has a first internal floor space (132) and there is a cabin floor space (130) external to the lavatory unit (103). The lavatory unit (103) is expandable into the PRM-accessible configuration in which the lavatory unit (103) is expanded to have a second internal floor space (132), the second internal floor space (132) encompassing a region of the cabin floor space (130). A sink for an aircraft lavatory unit is also disclosed.
Patent AU-2020335163-A1 (AU)
Title: Operating method for an elevator operating device with a touch-sensitive screen system
Inventor: ACKERMANN MARCEL
IPC: B66B1/46
Filed: 2020-08-21
Abstract: The invention relates to an elevator operating device (6) for a floor, having a touch-sensitive screen system (68) with a substantially smooth contact surface (35). Call symbols (23) can be visibly displayed on a user surface (34), one of which is to be contacted in order to enter a character stored for said call symbol (23). In order to enter a two-digit destination floor, the passenger (M) leaves the finger on the touch surface (35) after entering a first character, whereby the elevator operating device (6) detects that the passenger has limited vision. The elevator operating device (6) registers a second character when the operating device detects a confirmation operation for the second character without detecting that the finger has been lifted off the contact surface (35). As long as the finger is in contact with the contact surface (35), no destination call is generated. The destination call is generated only when the passenger (M) lifts the finger off the contact surface and thereby indicates that the input has ended.
Patent AU-2020354341-A1 (AU)
Title: Encoding and decoding a point cloud using patches for in-between samples
Inventor: ANDRIVON PIERRE
IPC: H04N19/597
Filed: 2020-09-15
Abstract: At least one embodiment relates to provides a method of encoding/decoding attribute of orthogonally projected 3D samples and in-between 3D samples in which an information indicates whether at least one first attribute patch of 2D samples obtained by encoding the attribute of said at least one orthogonally projected 3D samples according to a first attribute coding mode, and at least one second attribute patch of 2D samples of an image obtained by encoding the attribute of at least one in-between 3D sample, are stored in separate images.
Patent AU-2020381977-A1 (AU)
Title: Granular bacteria gastroprotected with a coating matrix in crystalline form, process for the preparation thereof and compositions thereof
Inventor: MOGNA Vera
IPC: C12N1/04
Filed: 2020-11-11
Abstract: The present invention relates to crystalline gastroprotected granular bacteria, such as bacterial strains in granular form coated with a lipid coating matrix, preferably in a reduced amount, said lipid coating matrix having a crystalline form. Furthermore, the present invention relates to a process for the preparation of said crystalline gastroprotected granular bacteria. Lastly, the present invention relates to a composition comprising said crystalline gastroprotected granular bacteria.
Patent AU-2020384208-A1 (AU)
Title: Use of MOG for priming a treatment for glioblastoma
Inventor: ROYBAL KOLE T
IPC: C07K14/725
Filed: 2020-11-06
Abstract: A method for treating a subject for glioblastoma is provided. In some embodiments, the method may comprise administering to a subject a molecular circuit that includes a binding triggered transcriptional switch (BTTS) that, when bound to MOG, induces one or more encoded therapeutics specific for one or more antigens expressed by the GBM. Nucleic acids containing sequences encoding all or portions of such circuits are also provided, as well as cells, expression cassettes and vectors that contain such nucleic acids. Also provided are kits for practicing the described methods.
Patent AU-2020402104-A1 (AU)
Title: Cancer classification using patch convolutional neural networks
Inventor: NICULA VIRGIL
IPC: G16B20/00
Filed: 2020-12-11
Abstract: Methods for determining a disease condition of a subject of a species are provided that comprises obtaining a dataset of fragment methylation patterns determined by methylation sequencing of nucleic acid from a biological sample of the subject. A fragment methylation pattern comprises the methylation state of each CpG site in the fragment. A patch including a channel comprising parameters for the methylation status of respective CpG sites in a set of CpG sites in a reference genome represented by the patch is constructed by populating, for each respective fragment in the plurality of fragments that aligns to the set of CpG sites, an instance of all or a portion of the plurality of parameters based on the methylation pattern of the respective fragment. Application of the patch to a patch convolutional neural network determines the disease condition of the subject.
Patent AU-2020408618-A1 (AU)
Title: Method and apparatus for determining timing advance, and device and medium
Inventor: DAI BO
IPC: H04W56/00
Filed: 2020-12-15
Abstract: Disclosed are a method and apparatus for determining a timing advance (TA), and a device and a medium. The method for determining a TA comprises: a terminal obtains TA list information, wherein the TA list information is sent by a base station to the terminal or configured by default to be stored in the terminal, the TA list information indicates at least one TA list, and each TA list comprises at least one TA value; the terminal obtains a target TA value according to the TA list information; the terminal adjusts the TA of uplink channel transmission by using the target TA value.
Patent AU-2020410995-A1 (AU)
Title: Stabilization of collagen scaffolds
Inventor: KLOPOTEK PETER J
IPC: A61F2/14
Filed: 2020-12-22
Abstract: Shape-stabilized collagen scaffolds and methods of obtaining such scaffolds are disclosed. Stroma can be harvested, for example, from, human or porcine comeal stroma and shaped during excision or in a separate step after excision. The scaffold can be compacted by removing some or all of the water from the scaffold, and rehydrating the scaffold in a controlled manner (e.g., in a mold or other confining space) such that the scaffold takes a desired compacted shape; and then crosslinking at least a portion of the scaffold to mechanically strengthen it and inhibit subsequent swelling. Various sources of energy can be employed to induce crosslinking of collagen including, for example, ultraviolet (UV) radiation. The scaffolds can also be selectively densified or patterned. The invention is particularly useful in forming scaffolds that are stable lenticules of enhanced stiffness and sufficient optical clarity for intracorneal implantation in additive ocular surgery.
Patent AU-2020462941-A1 (AU)
Title: Method for acylating a hydroxylated solid material
Inventor: SAMAIN DANIEL
IPC: D21H17/14
Filed: 2020-08-13
Abstract: The invention relates to a method for acylating a solid material (3, 9) carrying reactogenic hydroxyls, in which: - at least one fatty acid chloride (1) is distributed, at least over the surface of the solid material (3,9), by means of a distribution device (2) having an application surface: - the at least one fatty acid chloride (1) distributed at least over the surface of the solid material (3,9) is heated to a temperature, referred to as the acylation temperature, lower than the vaporisation temperature of the at least one fatty acid chloride (1), so as to allow acylation of the solid material (3,9), and; - a flow of a gaseous composition (6) is directed over the solid material (3,9) at the acylation temperature, so as to entrain at least some gaseous hydrochloric acid (7) formed as a result of the acylation reaction; characterised in that the application surface of the distribution device (2) is a pile provided with thread-like pile elements capable of: o filling with the at least one fatty acid chloride (1) by coming into contact with the at least one fatty acid chloride, and; o releasing the at least one fatty acid chloride by bringing the thread-like elements of the pile into contact with the solid material (3,9); the distribution step (12,14) being carried out in such a way as to distribute onto the solid material (3,9) a quantity of the at least one fatty acid chloride (1) of between 20 mg/m
Patent WO-2022040739-A1 (WO)
Title: Track tensioning system
Inventor: COLLINS ANDREW
IPC: B62D55/30
Filed: 2021-08-25
Abstract: A track tensioning system for adjusting tension in a vehicle track, comprising a track tensioner comprising a hydraulic cylinder and a piston assembly slidably moveable within the cylinder and dividing the cylinder into a first and second chamber each in selective fluid communication with a pressurised hydraulic fluid source and reservoir, such that supply or withdrawal of hydraulic fluid to or from the chambers causes the piston assembly to move within the cylinder in either extension, increasing track tension, or retraction, decreasing track tension, further comprising a locking system capable of mechanically locking the position of the piston assembly with respect to the hydraulic cylinder, wherein the locking system is switchable between an engaged mode, where it prevents movement of the piston, thereby maintaining tension in the vehicle track, and a disengaged mode, where it allows movement of the piston, thereby allowing tension in the vehicle track to be adjusted.
Patent AU-2021218244-A1 (AU)
Title: Machine learning modeling for protection against online disclosure of sensitive data
Inventor: MEJIA IRGELKHA
IPC: G06N3/02
Filed: 2021-08-23
Abstract: Systems and methods use machine learning models with content editing tools to prevent or 
mitigate inadvertent disclosure and dissemination of sensitive data. Entities associated with 
private information are identified by applying a trained machine learning model to a set of 
unstructured text data received via an input field of an interface. A privacy score is computed for 
the text data by identifying connections between the entities, the connections between the entities 
contributing to the privacy score according to a cumulative privacy risk, the privacy score 
indicating potential exposure of the private information. The interface is updated to include an 
indicator distinguishing a target portion of the set of unstructured text data within the input field 
from other portions of the set of unstructured text data within the input field, wherein a 
modification to the target portion changes the potential exposure of the private information 
indicated by the privacy score.
2/9 
200 
202 
RECEIVE A SET OF UNSTRUCTURED TEXT DATA 
204\ 
RECEIVE AN IMAGE OR VIDEO FILE IN ASSOCIATION WITH THE 
UNSTRUCTURED TEXT DATA 
206 1 
PROCESS THE IMAGE OR VIDEO FILE TO IDENTIFY METADATA 
208\I 
PROCESS THE TEXT DATA AND THE METADATA TO IDENTIFY A PLURALITY 
OF ENTITIES ASSOCIATED WITH PRIVATE INFORMATION USING A TRAINED 
MACHINE LEARNING MODEL 
210N 
COMPUTE A PRIVACY SCORE FOR THE TEXT DATA BY IDENTIFYING 
CONNECTIONS BETWEEN THE ENTITIES 
212 N 
UPDATE THE GRAPHICAL INTERFACE TO INCLUDE AN INDICATOR 
DISTINGUISHING A TARGET PORTION OF THE SET OF UNSTRUCTURED TEXT 
DATA WITHIN THE INPUT FIELD FROM OTHER PORTIONS OF THE SET OF 
UNSTRUCTURED TEXT DATA WITHIN THE INPUT FIELD 
214 
A MODIFICATION TO THE TARGET PORTION CHANGES THE POTENTIAL 
EXPOSURE OF THE PRIVATE INFORMATION INDICATED BY THE PRIVACY 
SCORE 
FIG. 2
Patent AU-2021222203-A1 (AU)
Title: Preparation and use of immunostimulatory coupling complex which is delivered and activated in targeted manner
Inventor: LIU CHEN
IPC: C07K5/093
Filed: 2021-02-20
Abstract: Provided are the preparation and use of an immunostimulatory coupling complex which is delivered and activated in a targeted manner. Specifically, provided are a compound as represented by Formula MI-S-C-A which is used as a connecting arm, and a pharmaceutical compound as represented by Formula MI-S-C-A-D, to which a dug is connected. The pharmaceutical compound has the advantages of improved water solubility, reduced cytotoxicity, and enhanced drug activity.
Patent AU-2021226570-A1 (AU)
Title: Cancer treatment methods
Inventor: ACKERMAN SHELLEY ERIN
IPC: A61K47/68
Filed: 2021-02-25
Abstract: The invention provides methods for treating cancer in a subject comprising administering an immunoconjugate of formula: Ab-[TA]
Patent AU-2021227295-A1 (AU)
Title: Method and kit for treating skin infections
Inventor: NIKINMAA SAKARI
IPC: A61K41/00
Filed: 2021-03-01
Abstract: Method and kit for topical treatment of a skin infection, in particular of superficial skin infections, caused by
Patent AU-2021244228-A1 (AU)
Title: Technologies for preventing or treating infections
Inventor: BAYDEN ALEXANDER SERGEI
IPC: A61K47/34
Filed: 2021-03-25
Abstract: Among other things, the present disclosure provides agents that can bind to viruses such as SARS-CoV-2 and/or cells infected thereby. In some embodiments, the present disclosure provides methods for preventing and/or treating conditions, disorders or diseases associated with SARS-CoV-2 infection. In some embodiments, the present disclosure provides methods for preventing and/or treating COVID-19.
Patent AU-2021261830-A1 (AU)
Title: Methods and processes for non-invasive assessment of genetic variations
Inventor: KIM SUNG K
IPC: C12Q1/68
Filed: 2021-11-01
Abstract: METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS 
Abstract 
Provided herein are methods, processes, systems, machines and apparatuses for non-invasive 
assessment of genetic variations.  
232