baber/WOPTO huggingface dataset:
Patent EP-1071825-B1 (EP)
Inventor: DE CANCK ILSE
IPC: C12Q1/6881
Filed: 1999-04-19
Granted: 2012-06-20
Abstract: La présente invention concerne le groupage d'allèles de HLA et notamment la séquence de l'exon 2 et de l'exon 3 des allèles HLA-B*3913, HLA-B*1406 et HLA-B*51nouveau et de l'exon 2 des allèles HLA-DRBI*0820, HLA-DRBI*04nouveau et HLA-DRB4*01nouveau. La présente invention concerne des méthodes de groupage de ces allèles. Dans un mode de réalisation préféré, ce groupage consiste : i) à amplifier un fragment déterminé de ces allèles en utilisant au moins une paire d'amorces appropriées ; ii) à hybrider le produit de l'amplification de la phase i) avec au moins une sonde s'hybridant spécifiquement à une région cible comprenant un ou plusieurs nucléotides polymorphes dans le fragment approprié ; iii) à déterminer, à partir du résultat de la phase ii) l'absence ou la présence de ces allèles dans l'échantillon. La présente invention concerne aussi des amorces et sondes destinées à s'utiliser dans ces méthodes de groupage. La présente invention concerne également une trousse de diagnostic comprenant ces amorces et sondes.
Patent EP-1103075-B1 (EP)
Inventor: STALMANS LIEVEN
IPC: H01L29/06
Filed: 1999-07-02
Granted: 2009-09-09
Abstract: A thin-film opto-electronic device on a conductive silicon-containing substrate includes a sequence of layers. The layers include a layer of a porous medium preferably a porous silicon, on a substrate. The porous layer has both light diffusing and light reflecting properties. In addition, a non-porous layer is located on said porous silicon layer, with at least one first region and at least one second region being in said non-porous layer. The first region is of a first conductivity type acting as a light absorber and the second region has a conductivity of a second type, different from said first conductivity type. The sequence of layers is such that optical confinement is realised in the device.
Patent EP-1093346-B1 (EP)
Inventor: GREENE GEORGE R JR
IPC: A61L31/18
Filed: 1999-07-02
Granted: 2006-03-15
Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site.
Patent EP-1102986-B1 (EP)
Inventor: GUEVREMONT ROGER
IPC: B01D59/46
Filed: 1999-08-05
Granted: 2005-11-02
Abstract: The present invention provides an apparatus for selectively transmitting ions and trapping the ions within a defined 3-dimensional space at atmospheric pressure. The invention is based on the ion focussing principles of high field asymmetric waveform ion mobility spectrometry in which an analyzer region is defined by a space between first and second spaced apart electrodes, the analyzer region having a gas inlet and a gas outlet for providing a flow of gas through the analyzer region. Ions which are introduced into the analyzer region are carried by a gas flow towards a gas outlet. At least one of the electrodes has a curved surface terminus located near the gas outlet and the gas flow is adjusted so that ions are trapped in a defined 3-dimensional space located near the tip of the terminus. Trapping of ions in a defined 3-dimensional space allows a more concentrated flow of desired ions.
Patent EP-1105407-B1 (EP)
Inventor: RAO MEENA
IPC: A61P31/04
Filed: 1999-08-12
Granted: 2007-10-10
Abstract: Newly isolated aminosterol compounds and pharmaceutical compositions based on the aminosterol compounds are described. Methods for the treatment of various disorders, for example, a microbial infection, are also described.
Patent EP-1121099-B1 (EP)
Inventor: ALAUX GERARD
IPC: A61P31/04
Filed: 1999-10-12
Granted: 2004-04-21
Abstract: The invention concerns a pharmaceutical composition with gastric residence and controlled release, characterized in that it comprises two or three layers and contains (a) an active principle associated with a excipient modifying its release; (b) a system generating carbon dioxide in a swelling polymer hydrophilic matrix; (a) and (b) capable of being included in a common layer or in separate layers.
Patent EP-1185181-B1 (EP)
Inventor: XUE JIANXIAN
IPC: A41D13/11
Filed: 1999-09-24
Granted: 2004-08-18
Abstract: La présente invention concerne un masque filtrant (10) comprenant un corps de masque (20) et une bande (30). Le corps de masque (20) est adapté à recouvrir le nez et la bouche du porteur et comprend des fibres contenant de la polyoléfine. La bande (30) comporte un composant élastique et un composant fibreux thermoplastique. Le composant fibreux thermoplastique présente une température de fusion maximale d'environ 250 °C et est constitué de polyoléfine ou de polyoléfine substituée. La bande (30) est fixée au corps de masque par la chaleur et la pression à des points de fixation (23).
Patent EP-1230814-B1 (EP)
Title: Procede et systeme de commande de produits
Inventor: RITTER RUDOLF
IPC: G06Q30/00
Filed: 1999-11-16
Granted: 2006-03-01
Abstract: L'invention concerne un procédé permettant à un abonné mobile de commander des produits (1) dans un réseau radiotéléphonique mobile (4). Ce procédé comprend les étapes suivantes : acquisition d'une image correspondant au produit à commander (1) ; association du fichier image à une identification personnelle de l'abonné mobile ; transmission du message de commande associé (31) à un serveur (5) dans ledit réseau radiotéléphonique mobile (4) ; comparaison dudit fichier image avec des images mémorisées dans une banque de données de produits (50), chaque image de ladite banque de données (40) étant associée à une identification du vendeur de produit (8) ; envoi d'un message (52), contenant une identification du produit commandé (1) et de l'abonné mobile passant la commande, au vendeur (8).
Patent EP-1086613-B1 (EP)
Inventor: HAYWARD C MICHAEL
IPC: H05K9/00
Filed: 1999-06-08
Granted: 2006-03-15
Abstract: A modular card cage allows for improved access to the rear panel of a backplane, while providing for enhanced EMI shielding. First and second side panels, in combination with top and bottom covers, form the card cage. The top and bottom covers are adapted for removably mounting to the side panels, and, when mounted, provide lateral rigidity to the card cage. At least one of the top and bottom covers comprises a front portion and a rear portion. The front portion of the cover is preferably separable from the rear portion such that one of the front and rear portions is removable from the side panels, while the other of the front and rear portions remains mounted for providing lateral rigidity. EMI shielding is provided in all portions of the cage, including the removably mounted covers, preferably by means of embedded, continuous gasketing. In this manner, a cost effective card cage is provided that is relatively simple to assemble and provides improved lateral and torsional rigidity over conventional configurations, while maintaining EMI shielding requirements.
Patent EP-1131833-B1 (EP)
Inventor: ERK THOMAS
IPC: H01H33/66
Filed: 1999-10-12
Granted: 2002-06-05
Abstract: L'invention concerne des installations de commutation comportant des appareils de commutation pouvant être commandés par des dispositifs d'entraînement magnétiques, en particulier des disjoncteurs à vide, lesdits appareils de commutation étant disposés conformément au nombre des phases à commuter, chaque fois sous forme d'un bloc, dans un boîtier qui les entoure chacun sur trois côtés et dans lequel ils sont fixés par vissage, de façon libérable, par une pièce de connexion de contact supérieure et une pièce de connexion de contact inférieure. Les appareils de commutation (VS) sont pourvus de boîtiers séparés qui sont formés chacun par deux coques polaires (PS) disposées l'une en face de l'autre de façon spéculaire, et la pièce de connexion de contact supérieure et la pièce de connexion de contact inférieure (KAo, KAu) forment respectivement un corps de refroidissement supérieur et un corps de refroidissement inférieur (KKo, KKu) qui sont chacun fixés, de façon libérable, entre deux nervures de fixation de disjoncteur à vide (VB...), séparément associées, des coques polaires (PS). Le corps de refroidissement supérieur (KKo) est pourvu, dans la zone périphérique des appareils de commutation (VS), de fentes d'aération (LS...) qui s'étendent centralement par rapport à ces appareils de commutation, et le corps de refroidissement inférieur (KKu) est pourvu, dans la zone périphérique des appareils de commutation (VS), d'ouvertures d'entrée d'air (LE...) disposées symétriquement par rapport à l'axe central. De telles installations de commutation sont utilisées pour l'alimentation en énergie et la distribution d'énergie.
Patent EP-1135892-B1 (EP)
Inventor: BENZ MICHAEL
IPC: H04Q3/00
Filed: 1999-11-25
Granted: 2008-03-05
Abstract: Selon l'invention, une distinction est établie pour un système de communication (par ex. un SUTM à interface radio AMRC) entre des services présentant une dynamique de débit binaire élevée et des services présentant une dynamique de débit binaire faible, le mode de signalisation des formats de transports utilisés étant adapté en fonction de cette distinction. Le débit binaire des données d'un service peut, au fil du temps, fluctuer fortement et/ou rapidement (dynamique élevée) ou ne subir qu'une fluctuation faible et/ou lente (dynamique faible). Les données des services sont transmises sur un canal physique commun. Une signalisation intrabande est utilisée pour la signalisation du format de transport des services présentant une dynamique de débit binaire élevée, et une signalisation dans un canal séparé est utilisée pour les services présentant une dynamique de débit binaire faible.
Patent IE-86568-B1 (IE)
Title: Long range wireless network and ad hoc connectivity
Inventor: OLARAN ANDER GRAY
IPC: H04W72/00
Filed: 2013-01-31
Abstract: This invention relates to method to build a long range wireless network with the ability to add wireless devices at will in an ad hoc manner. The method entails the steps of waking wireless devices within range by transmitting a beacon signal. The wireless devices can include wireless repeaters which can extend the range of the network. The method allows the use of high powered devices and allows them to be battery powered. the method includes a means to prevent the wireless devices transmitting simultaneously thus avoiding collisions of the wireless signals. The allows the method to be reliable and robust. The method also allows systems build according to this invention to be both FCC and ETSI compliant.
Patent IT-1277170-B1 (IT)
Inventor: NANI EROS
IPC: B01D46/24
Filed: 1995-03-20
Granted: 1997-11-05
Abstract: PCT No. PCT/IT96/00048 Sec. 371 Date Sep. 29, 1997 Sec. 102(e) Date Sep. 29, 1997 PCT Filed Mar. 15, 1996 PCT Pub. No. WO96/29139 PCT Pub. Date Sep. 26, 1996A self-cleaning filter for pneumatic circuits includes a filtering baffle (1) mounted on a drum (2) rotated steadily, the flow (A) of the air to be filtered being from outside to inside the baffle (1), as well as a suction mouth (5) longitudinally positioned in the vertical mid-plane at the lowest point of the baffle (1) and externally adjacent thereto, and a blowing nozzle (6) internally adjacent to the baffle (1) at a position exactly opposite the mouth (5), both the mouth (5) and the nozzle (6) extending along the whole length of the filtering baffle (1). The nozzle (6) has a plurality of aligned bores suitable to emit a narrow jet of counter-current air, with adjustable incidence, and the mouth (5) is shaped as a trapezoidal hopper with a small adjustable blowing nozzle (C) at one end.
Patent IT-1267845-B1 (IT)
Title: Anatomical support, particularly for users in squatting positions
Inventor: CAZZOLA FRANCO
IPC: A47C/
Filed: 1994-08-03
Granted: 1997-02-18
Abstract: An anatomical support, particularly for users in squatting positions, comprising a frame 2, moveably coupled to each of the user's legs, with a front part 3 for supporting the knee and a rear part 4 for supporting the top part of the thigh, maintaining the ankle raised from the ground. Adjustment means are envisaged for selectively varying the distance between these parts 3, 4 in such a way as to adapt the support to the size of the user. These adjustment means consist of a telescopic coupling 8, 8' between the parts 3, 4 with means of clamping 18 in a predetermined position. A first oscillating bearing 11 mounted on the front part 3 houses the knee and is associated with a first elastic anchoring belt 13, a second bearing 14 fixed on the rear part 4 is associated with a second belt 17 to support the ankle and support the thigh at the top. <IMAGE>
Patent JP-2912365-B1 (JP)
Title: 長期間試験システム、試験用容器および測定用容器
IPC: G01N1/22
Filed: 1998-06-29
Granted: 1999-06-28
Abstract: 【要約】
【課題】  １ｐｐｍ以下の極低酸素環境に設定された環 境を長期間保持することができ、さらには、外部空気の 混入がない高精度な分析が簡単にできる長期間試験シス テム、その試験用容器および測定用容器を提供する。
【解決手段】  試験片を試験用容器１の収納本体２側に 収納する（）。収納本体２と管状蓋体３をバーナーな どの溶着手段１０によって溶接接合し（）、地下環境 シュミレーション装置内に搬入する（）。地下環境シ ュミレーション装置内では、開閉手段９を開いた状態に して真空引きを行い一旦閉じる（）。次に、流体導入 口８を試験溶液導入管２０と連結し、開閉手段９を開い て試験溶液２１を試験用容器１内に充填する（）。地 下環境シュミレーション装置内で開閉手段９を閉じる （）。開閉手段９を閉じた状態で試験用容器１を地下 環境シュミレーション装置の外に出し細口管部６を溶着 閉塞し（）、切断する（）。恒温保持容器２２に保 管する（）。
Patent JP-2926492-B1 (JP)
Title: 植栽樹木の根鉢固定方法及び装置
IPC: A01G17/04
Filed: 1998-07-10
Granted: 1999-07-28
Abstract: 【要約】
【課題】コンクリート建築物の屋上等のように土壌の深 さが限定されている床面上に植栽樹木を簡単な方法で移 植すると共に、この植栽樹木の自立補助を堅固にし、し かも自立補助に用いた締結具等を地面から露出しないよ うにした植栽樹木の根鉢固定方法及び装置を提供する。
【解決手段】放射状に形成されたベース基材２、２…の 各先端部に安定板５を固設して屋上等の床面１４に設置 して成る基台１の上部に根鉢１１を載置し、夫々のベー ス基材２の長尺方向に形成された係止片２ａに沿って移 動自在に係合した結合部材４に固設された支柱３に肩当 て板７を有する変位部材６を挿入し、肩当て板７が根鉢 １１の肩部に当たる高さで夫々の変位部材６に設けられ た貫通孔６ａと夫々の支柱３の上下方向に設けられた複 数の貫通孔３ａの一つとを合致してボルト締結する一 方、支柱３を根鉢１１の周囲に打設した後、夫々の肩当 て板７に固設された牽引環９に１本のベルト１０を順次 通して締結することにより、根鉢１１の肩部周辺をベル ト１０で係止するようにした。
Patent JP-3049246-B1 (JP)
Title: 溶融めっき設備
IPC: C23C2/00
Filed: 1999-10-04
Granted: 2000-06-05
Abstract: 【要約】
【課題】  簡単な構成で溶融めっき材の温度が不安定に なるのを防止でき、しかも設備の熱効率が向上する溶融 めっき設備を提供する。
【解決手段】  めっき対象物１が浸漬される溶解炉３近 傍までめっき材のインゴット６を搬送するインゴット搬 送装置７をインゴット予熱炉８で内包し、インゴット予 熱炉８に加熱炉２の排ガスＧを導入して、インゴット６ をその融点未満に予熱する。
Patent NO-327728-B1 (NO)
Inventor: RANTALA PERTTI TAPANI
IPC: A61K9/48
Filed: 2000-03-17
Abstract: Composition comprising a salt of dichloromethylene bisphosphonic acid (I; clodronate) and silicified microcrystalline cellulose as an oral solid dosage form, is new : Independent claims are also included for the manufacture of the oral dosage forms. ACTIVITY : Hypocalcemic.
Patent NO-328128-B1 (NO)
Inventor: GISSMANN LUTZ
IPC: C12N15/62
Filed: 2000-04-06
Abstract: Vaccine formulations comprising viral capsomeres are disclosed along with methods for their production. Therapeutic and prophylactic methods of use for the vaccine formulations are also disclosed.
Patent NO-322644-B1 (NO)
Inventor: PASQUET GEORGES
IPC: A61P9/10
Filed: 2001-04-06
Abstract: The invention relates to the use of compounds of the formula I: wherein: ring C is a 5-6 membered heterocyclic moiety; Z is -O-, -S-, or -CH<SUB>2</SUB>-; R<SUP>1 </SUP>is hydrogen, C<SUB>1-4</SUB>alkyl, C<SUB>1-4</SUB>alkoxymethyl, di(C<SUB>1-4</SUB>)alkoxy)methyl, C<SUB>1-4</SUB>alkanoyl, trifluoromethyl, cyano, amino, C<SUB>2-5</SUB>alkenyl, C<SUB>2-5</SUB>alkynyl, carboxy, C<SUB>3-7</SUB>cycloalkyl, C<SUB>3-7</SUB>-cycloalkylC<SUB>1-3</SUB>alkyl, or an optionally substituted group selected from phenyl, benzyl, phenylC<SUB>2-4</SUB>alkyl and a 5-6 membered heterocyclic group; n is an integer from 0 to 5; m is an integer from 0 to 3; R<SUP>2 </SUP>represents hydrogen, hydroxy, halgeno, cyano, nitro, trifluoromethyl, C<SUB>1-3</SUB>alkyl, C<SUB>1-3</SUB>alkoxy, C<SUB>1-3</SUB>alkylsulphanyl, -NR<SUP>3</SUP>R<SUP>4 </SUP>(wherein R<SUP>3 </SUP>and R<SUP>4</SUP>, which may be the same or different, each represents hydrogen or C<SUB>1-3</SUB>alkyl), or R<SUP>5</SUP>X<SUP>1</SUP>- (wherein X<SUP>1 </SUP>represents a direct bond, -CH<SUB>2</SUB>-, or a heteroatom linker group and R<SUP>5 </SUP>is an alkyl, alkenyl or alkynyl chain optionally substituted by for example hydroxy, amino, nitro, alkyl, cycloalkyl, alkoxyalkyl, or an optionally substituted group selected from pyridone, phenyl and a heterocyclic ring, which alkyl, alkenyl or alkynyl chain may have a heteroatom linker group, or R<SUP>5 </SUP>is an optionally substituted group selected from pyridone, phenyl and a heterocyclic ring, and salts thereof, in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals, processes for the preparation of such compounds, pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof as active ingredient and compounds of formula I. The compounds of formula I and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.
Patent NO-332600-B1 (NO)
Inventor: BOYADJIEFF GEORGE
IPC: E21B19/16
Filed: 2001-10-31
Abstract: An iron roughneck has a pair of upper jaws carrying pipe gripping dies for gripping tool joints. The jaws have recesses formed on each side of the pipe gripping dies to receive spinning rollers. By positioning the spinning rollers in the upper jaws at the same level as pipe gripping dies, the spinning rollers are able to engage the pipe closer to the lower jaws and thus can act on the tool joint rather than on the pipe stem.
Patent NO-319193-B1 (NO)
Inventor: LUMPIOLA TERO
IPC: F24F13/06
Filed: 2002-10-08
Abstract: A directional air diffuser is disclosed comprised of an inlet air diffuser having mounted thereon a directional element (4) with the shape of a circular segment, the inlet air diffuser comprising a diffuser body (1) connected to the inlet air duct and a diffuser disc (2) adapted movable substantially in the axial direction of the diffuser body so as to provide a substantially annular inlet air flow gap (3) therebetween. The invention is implemented by way of using a directional element (4) that has a radius of curvature substantially equal to that of the annular inlet air gap (3) at the outer periphery thereof and the directional element is mounted on the outer periphery of the annular inlet air gap so as to cover a portion of said annular inlet air gap. <IMAGE>
Patent NO-332019-B1 (NO)
Inventor: MONTGOMERY PETER JAMES
IPC: B63B21/00
Filed: 2005-02-21
Abstract: A vessel mooring system which includes at least two mooring robots that can be secured to a terminal and/or a vessel, each robot includes an attractive force attachment element and a base structure. The attachment element can be engaged with a vertically extending side surface and to exert an attractive force normal to the surface. Each robot can measure the attractive force between the attachment element and the surface to provide an “attractive force capacity reading”. The force between the attachment element and the fixed structure of the mooring robot can be measured to provide a “normal force reading”. From monitoring of the relationship between the attractive force capacity reading and the normal force a control of the mooring robot can be provided such that if there is a tending to separate the attachment elements from said vessel the attractive force may be increased and/or alarm is sounded.
Patent NO-332047-B1 (NO)
Title: Lavspenningsmodul
Inventor: MERKEL HANS-PETER
IPC: H02J13/00
Filed: 2005-11-03
Abstract: Oppfinnelsen vedrører en koblingsmodul (1) for å styre og overvåke en elektrisk forbruker i utgangen av et lavspent koblingsanlegg, hvor nevnte modul omfatter et kommunikasjonsgrensesnitt for kobling til et buss-system, en programmerbar styreenhet og parametriske sikringsfunksjoner og som konfigureres fra individuelle vekslende komponenter. Nevnte modul får minst én sentralenhet (2) og en bussforbindelsesenhet (6) og utstyres også med forbindelsesposisjoner for å motta kraftenheter (4) og inngangs-/utgangsenheter (7). Sentralenheten (2) kommuniserer med de gjenstående komponentene i koblingsmodulen (1) via en intern buss.
Patent NO-331991-B1 (NO)
Title: produksjons- og lastesystem for transport av fluider
Inventor: GUDMESTAD OVE TOBIAS
IPC: B63B/
Filed: 2005-11-04
Abstract: Et lastesystem for transport av fluider, så som hydrokarboner, fra en brønn (13) på en sjøbunn (14) til et fartøy (120) som flyter på havoverflaten (11). Lastesystemet omfatter en fleksibel stigeledningsinnretning som strekker seg oppover fra brønnen (13) til fartøyet (10), idet den fleksible stigeledning er konfigurert for å kunne koples fra fartøyet (10). Den fleksible stigeledningsinnretning omfatter en nedre fleksibel slange (21), idet den øvre ende på denne er koplet til en neddykket manifold (20), og en øvre fleksibel slange (22) der den nedre ende på denne slange er koplet til manifolden (20), mens den øvre ende på den fleksible slangen (22) er koplet til et egnet koplingspunkt på fartøyet (10).
Patent NO-341777-B1 (NO)
Title: Steng omfattende en elektrisk pumpe og en induktiv kopler
Inventor: PATEL DINESH R
IPC: E21B17/02
Filed: 2007-06-21
Abstract: Et system for bruk i en brønn inkluderer en streng for anbringelse i brønnen, hvori strengen inkluderer en elektrisk pumpe og en første induktiv koplerdel. En kompletteringsseksjon utplasseres i en sone av brønnen som skal utvikles, hvor kompletteringsseksjonen inkluderer en andre induktiv koplerdel for induktiv kopling til den første induktive koplerdel. En elektrisk innretning er elektrisk forbundet til den andre induktive koplerdel.
Patent NO-330584-B1 (NO)
Title: CO2-innfanging i saltsmelter
Inventor: OLSEN ESPEN
IPC: C01B32/50
Filed: 2009-05-28
Abstract: Foreliggende oppfinnelse vedrører en fremgangsmåte for innfangning av karbondioksid, CO2 fra avgass ved anvendelse av metalloksider oppløst i saltsmelter som absorpsjonsmedium.
Patent NO-336945-B1 (NO)
Title: Sammenleggbar fleksibel skulderbæreanordning
Inventor: WINGER JULIUS ANDREAS
IPC: A47D13/02
Filed: 2011-09-21
Abstract: Formålet med den foreliggende oppfinnelse er 4-delt: Den er designet slik at den støtter barnet komfortabelt på skuldrene av transportøren; rammen er dimensjonert slik at den enkelt kan løftes opp på skuldre. Bæresystemet er videre slik at hele oppfinnelsen er sammenleggbar slik at den kan tas med i vogn, i bil eller lett kan stues bort annet sted samt anpasses til alle skulderstørrelser ved et fleksibelt bæresystem.
Patent PL-142641-B1 (PL)
Title: Process for manufacturing novel muramyl peptides
IPC: C07H15/00
Filed: 1983-07-21
Abstract: The compounds of the formula I    <IMAGE>  (I)    <IMAGE>  in which each of R1, R4 and R6, independently of the others, represents hydrogen or lower alkanoyl, R2 represents C1-4-alkyl, hydroxymethyl or phenyl, R3 represents hydrogen or methyl, R5 represents hydrogen or C1-3-alkyl, R7 represents C1-3-alkyl that is unsubstituted or substituted by hydroxy, mercapto or methylthio, R8 represents hydrogen or lower alkyl, X represents oxygen or the group NH, Y represents C1-4-alkylidene, and each of R9 and R10, independently of the other, represents C11-17-alkyl or C11-17-alkenyl, and their salts, have an immunostimulating activeity.
Patent PL-149929-B1 (PL)
Title: Method of obtaining imidazole derivatives of mevalon lactone
IPC: G02B6/44
Filed: 1986-05-21
Abstract: Compounds of the formula  <IMAGE>  and the pharmaceutically acceptable acid addition salts thereof, wherein the various substituents are defined hereinbelow, the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.