baber/WOPTO huggingface dataset:
Patent CA-2585267-A1 (CA)
Title: Modified bacteriophage vectors and uses thereof
Inventor: ZANGHI CHRISTINE N
IPC: A61K48/00
Filed: 2005-10-05
Abstract: Provided herein are modified phage surface polypeptides, phages with modified surface polypeptides, nucleic acids that encode the modified surface polypetides, and related vectors and phages comprising the vectors. The provided phage surface polypeptides optionally comprise one or more modifications, including, for example, one or more modifications to enhance targeting to an antigen-presenting cell and one or more modifications that destabilize a viral capsid. Further provided herein are methods of making a lambda phage with a modified surface polypeptide and methods of making a lambda phage with a plurality of modified surface polypeptides. Also provided herein are antigen delivery systems comprising the modified phages of the invention and methods of promoting an antigenic response in a subject by administering to the subject the antigen delivery system of the invention, alone or in combination with other immunization modalities.
Patent CA-2585297-A1 (CA)
Inventor: FILIPPI FILIPPO
IPC: A61M5/178
Filed: 2005-09-15
Abstract: A syringe (1) comprises a barrel (2) for containing a substance to be injected, a needle carrier (12) for carrying a needle (10), and a plunger (3) which is adapted to be movable in the barrel 2 to expel the substance to be injected from the needle (10). The plunger (3) has a first part (3a), a second part (3b) and a resilient member (6) therebetween, the first (3a) and second (3b) parts being adapted to be releasably locked together to hold the resilient member (6) in a compressed state. In use, the first part 3a of the plunger (3) and the needle carrier (12) are adapted to engage one another following expulsion of the substance, and the second part (3b) of the plunger (3) is adapted to be unlocked from the first part (3a) following said engagement, allowing the resilient member (6) to expand to propel the needle carrier (12) into the barrel (2).
Patent CA-2590765-A1 (CA)
Inventor: SCHARER PETER
IPC: B65G69/28
Filed: 2007-05-25
Abstract: A ramp formable into a roll includes a plurality of segments, each of the segments having a pair of structural members and a load support that extends between the structural members. A male connector is positioned at a male end and a female connector is positioned at a female end of each of the structural members. Segment connecting links are provided having spaced pivot pins. One of the pivot pins is pivotally connected to a pivot pin aperture at the male end of the structural members and another of the pivot pins is pivotally secured to a pivot pin aperture at the female end of the structural members. The segments pivot between an operative position in which the male connector and the female connector are engaged and a stored position in which the segments are formed into a roll.
Patent CA-2591111-A1 (CA)
Title: Excavating machine for rocky and other soils
Inventor: HOLTMEIER JERRY
IPC: E02F5/04
Filed: 2005-12-08
Abstract: A trench excavating machine includes an excavating wheel on which are mounted spaced apart peripheral plates equipped with ripping teeth and spades. The ripping teeth are angled outward from the plates at an acute angle directed in the direction of rotation of the cutting wheel to attack the leading edge of a trench being excavated. Ripping teeth and spades are arranged at varying spacing on succeeding plates about the centerline of the cutting wheel. A  transverse conveyor located within the circumference of the cutting wheel transports spoil to the side of the cutting wheel. A spoil deflector removes spoil adhered to the inside of the cutting wheel.
Patent CA-2592207-A1 (CA)
Inventor: SHAH VISHAL
IPC: C12P1/02
Filed: 2005-12-22
Abstract: The preparation and use of 17-L-[(2'-O- ~-D-glucopyranosyl-p-D~glucopyranosyl)-oxy]-cis-9-octadecenoate, Lactonic and Open ring 17-L-[(2'-O-p~D-glucopyranosyl-~-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Methyl 17-L~[(2'-O-~-D-glucopyranosyl-~-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Ethyl 17-L-[(2'-O-~-D-glucopyranosyl-~-D-glucopyranosyl)-oxy]-cis-9-octadecenoate, Hexyl 17-L-[(2'-O-~-D-glucopyranosyl-p-D-glucopyranosyl)-oxy]-cis-9~octadecenoate, Ethyl 17-L-[(2'-O-~-D-glucopyranosyl-~-D-glucopy ranosyl)-oxy]~cis-9-octadecenoate-6"-acetate and Ethyl 17-L-[(2'-O-~-D-glucopyranosyl-~-D~gIucopyranosyl)-oxy]-cis-9-octadecenoate-6' ,6"-diacetate sophorolipids as antifungal agents.
Patent CA-2595385-A1 (CA)
Title: Pharmaceutical lipid compositions
Inventor: TIBERG FREDRIK
IPC: A61K9/127
Filed: 2005-12-09
Abstract: The present invention relates to a particulate composition containing; a) 5 to 90% of at least one phosphatidyl choline component b) 5 to 90% of at least one diacyl glycerol component, at least one tocopherol, or mixtures thereof, and c) 1 to 40% of at least one non-ionic stabilising amphiphile, where all parts are by weight relative to the sum of the weights of a+b+c and where the composition contains particles of at least one non-lamellar phase structure or forms particles of at least one non-lamellar phase structure when contacted with an aqueous fluid. The invention additionally relates to pharmaceutical formulations containing such compositions, methods for their formation and methods of treatment comprising their administration.
Patent CA-2596078-A1 (CA)
Title: End effector for surgical instrument, surgical instrument, and method for forming the end effector
Inventor: PALMER MATTHEW A
IPC: A61B17/28
Filed: 2006-01-31
Abstract: An end effector for an endoscopic surgical instrument having a longitudinal body with proximal and distal ends and an actuator at the proximal end of the body includes a clevis to be connected to the distal end of the body and two jaws. Each of the jaws has a tang portion (240) pivotally connected to the clevis and to be connected to the actuator for pivoting the jaw. The jaw has body portion (221, 223) with a lateral side (223) having substantially straight opposing edges and a proximal portion (227) connecting the lateral side to the tang portion and a nose portion (225, 229) connected to the lateral side and having substantially linear edges at an angle to the edges of the lateral side. The hollow body and nose portions define a biopsy cup for receiving a tissue sample therein and the opposing and linear edges form a pinching surface for contacting extremities of the tissue sample.
Patent CA-2597216-A1 (CA)
Title: Irrigation/aspiration system
Inventor: DAVIS SHERMAN G
IPC: A61B17/00
Filed: 2007-08-14
Abstract: A surgical system with irrigation and aspiration lines having different compliance or stiffness, with the irrigation line having a higher compliance than the aspiration line.
Patent CA-2598568-A1 (CA)
Title: Piperidinyl piperidine derivatives useful as inhibitors of chemokine receptors
Inventor: MILLER MICHAEL W
IPC: C07D401/14
Filed: 2006-02-21
Abstract: In its many embodiments, the present invention provides a novel class of compounds of structural formula (IA) or (IB) where R1-R8 are as disclosed herein as inhibitors of the CCR5 receptors, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with CCR5 using such compounds or pharmaceutical compositions. The invention also relates to the use of a combination of a compound of this invention and one or more antiviral or other agents useful in the treatment of Human Immunodeficiency Virus (HIV). The invention further relates to the use of a compound of this invention, alone or in combination with another agent, in the treatment of solid organ transplant rejection, graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis.
Patent CA-2599318-A1 (CA)
Inventor: UEDA TAKASHI
IPC: C08J3/12
Filed: 2005-12-13
Abstract: A novel method of particle formation by which the target aggregated latex particles can be efficiently recovered from a polymer latex under temperature conditions which are as wide as possible without deteriorating the original quality possessed by the polymer itself, while inhibiting secondary aggregation and fine-particle generation. The process for producing aggregated latex particles is characterized by atomizing or dropping a polymer latex in a gas phase containing an inorganic salt and/or acid in an aerosol state and causing the droplets of the polymer latex to fall or come into an aqueous phase containing a dispersant. Preferably, the process is further characterized in that the polymer latex contains a water-soluble polymer having the property of forming a physical gel.
Patent CA-2600543-A1 (CA)
Title: Method for ensuring the accessibility of communication network subscribers
Inventor: LOEBIG NORBERT
IPC: H04L12/18
Filed: 2006-02-16
Abstract: According to prior art, for example in the event of there being an imminent high level of danger or ecological catastrophe, the population is alerted/warned by sirens, radio or television. This method of alerting the population is limited however, and does not ensure that the people informed have actually been reached. The aim of the invention is to solve this problem.  To this end, an individual accessibility profile specific to each subscriber is created when the communication connection is established, and a connection to the at least one communication terminal is established as required, according to the data stored in the accessibility profile, the information being supplied to the subscriber by means of said connection when the subscriber is reached, and acknowledged by the subscriber on receipt thereof.
Patent CA-2602265-A1 (CA)
Inventor: GURNEY MARK E
IPC: C12Q1/68
Filed: 2006-03-30
Abstract: Polymorphisms in the FLAP and LTA4H gene are shown by genetic association analysis to be susceptibility markers for myocardial infarction (MI) and ACS, as well as stroke and PAOD. Pathway targeting for treatment and diagnostic applications in identifying those who are at risk of developing MI, ACS, stroke or PAOD, in particular are described. The invention also provides methods of prophylaxis therapy for MI in human subjects having a race including black African ancestry by administering to the subject a composition comprising a therapeutically effective amount of MI therapeutic agent that inhibits leukotriene synthesis in vivo. The invention also provides for compositions comprising a leukotriene synthesis inhibitor and a statin and methods of using these compositions to reduce C-reactive protein in a human subject at risk of MI, ACS, stroke and/or PAOD.
Patent CA-2602338-A1 (CA)
Inventor: HU XU
IPC: C12N15/82
Filed: 2006-03-21
Abstract: The present invention provides compositions and methods for regulating expression of heterologous nucleotide sequences in a plant. Compositions include a novel nucleotide sequence for a root-preferred and inducible promoter for the gene encoding a soybean dirigent protein. A method for expressing a heterologous nucleotide sequence in a plant using the promoter sequences disclosed herein is provided. The method comprises stably incorporating into the genome of a plant cell a nucleotide sequence operably linked to the root-preferred promoter of the present invention and regenerating a stably transformed plant that expresses the nucleotide sequence.
Patent CA-2604519-A1 (CA)
Title: Resetting of multiple processors in an electronic device
Inventor: GINGGEN ALEC
IPC: G06F1/24
Filed: 2007-09-27
Abstract: Automatic resetting of group of multiple processors in an electronic device wherein the processors are arranged in either a cascade chain or master-slave configuration. Upon the receipt of an originating reset signal by any one of the multiple processors the remaining processors are reset upon receipt of a forced reset signal generated by one of the processors in the group. The system states prior to the originating reset of each processor is refreshed to ensure compatible synchronization of system states and thus proper communication among the processors.
Patent CA-2605707-A1 (CA)
Inventor: DEMOPOULOS HARRY B
IPC: A61K48/00
Filed: 1997-12-31
Abstract: A method of increasing glutathione levels in mammalian cells comprising administering an oral bolus of encapsulated pharmaceutically stabilized glutathione in a rapidly dissolving formulation to a mammal on an empty stomach. Pharmaceutical formulations including glutathione are also disclosed.
Patent CA-2606170-A1 (CA)
Title: Actuator for use with electrical switches
Inventor: LEDDUSIRE RON
IPC: H01H33/59
Filed: 2006-04-28
Abstract: A device includes an actuator and a connecting member. The actuator is structured to physically contact a switch, the switch is structured to open and close an electrically conductive path when an external force is applied to the actuator, and the electrically conductive path is configured to supply electrical power to an electrical appliance. The connecting member is structured to attach the actuator to the electrical appliance. The actuator is capable of movement relative to the connecting member when the actuator is attached to the electrical appliance by the connecting member and when the external force is applied to the actuator.
Patent CA-2608355-A1 (CA)
Title: Delivery device allowing visual inspection of an intraluminal device
Inventor: MANGIARDI ERIC K
IPC: A61F2/84
Filed: 2006-05-12
Abstract: A delivery device (10) for positioning and deploying an implantable device (16) within a lumen is provided. The device includes a longitudinal outer tube (14) having proximal and distal ends, wherein the implantable device is positioned proximate to the distal end of the outer tube. The device also includes a longitudinal inner tube (12) slidably disposed within the outer tube and having proximal and distal ends, wherein el least a portion of the distal end of the inner tube is configured to underlie at least a portion of a proximal end of the implantable device. The distal end of the inner tube is located proximally of the distal end of the outer tube to define a gap for accommodating at least a portion of the implantable device. A mechanism (20) is coupled to the inner and/or outer tubes and is operable to deploy the implantable device within the lumen.
Patent CA-2610483-A1 (CA)
Inventor: JOHNSON KEVIN M
IPC: H01L41/08
Filed: 2006-05-31
Abstract: La présente invention se rapporte à un transducteur acoustique, qui permet de convertir un mouvement mécanique en énergie acoustique. Le transducteur acoustique selon l'invention peut comprendre un diaphragme et un support situé sur une partie du diaphragme. Un actionneur peut être couplé de manière fonctionnelle à une seconde partie du diaphragme. Le support et l'actionneur peuvent être adaptés pour être sensibles aux conditions environnementales ambiantes, telles que la chaleur et/ou l'humidité, ce qui permet de maintenir sensiblement l'efficacité acoustique du diaphragme.
Patent CA-2612081-A1 (CA)
Title: 2,5-bis-diamimne [1 , 4] benzoquinone-derivatives
Inventor: BANZI RITA
IPC: C07C225/28
Filed: 2006-06-13
Abstract: Synthesis of 2,5-bis-diamine-[l,4]benzoquinonic derivatives having the general formula (I), products and intermediates of said synthesis; the synthesis involves the use of p-benzoquinones having the general formula (IX) and diamines having the general formula (XI).
Patent CA-2612162-A1 (CA)
Title: Use of oligonucleotides in steroid refractory or steroid dependent inflammatory conditions
Inventor: LOFBERG ROBERT
IPC: A61P29/00
Filed: 2006-06-29
Abstract: The present invention makes it possible to enhance steroid efficacy in a steroid refractory or dependent patient afflicted with an inflammatory condition not responding or responding poorly or inadequately to anti-inflammatory treatment, by administering an oligonucleotide having the sequence 5 5'-Xm-CG-Yn-3' in an effective amount to said patient and wherein X  is A, T, C or G, Y is A, T, C, or G, m=1-100, n=1-100 and wherein at least one CG dinucleotide is ummethylated. The invention also encompasses the use of said oligonucleotide for the manufacture of pharmaceuticals.
Patent CA-2614384-A1 (CA)
Title: Concept for bridging the gap between parametric multi-channel audio coding and matrixed-surround multi-channel coding
Inventor: SPERSCHNEIDER RALPH
IPC: G10L19/00
Filed: 2006-06-21
Abstract: The purpose of the invention is to bridge the gap between pa-rametric multi-channel audio coding and matrixed-surround multi-channel coding by gradually improving the sound of an up-mix signal while raising the bit-rate consumed by the side-information starting from 0 up to the bit-rates of the parametric methods. More specifically, it provides a method of flexibly choosing an "operating point" somewhere between matrixed-surround (no side-information, limited audio qual-ity) and fully parametric reconstruction (full side-information rate required, good quality). This operating point can be chosen dynamically (i.e. varying over time) and in response to the permissible side-information rate, as it is dictated by the individual application.
Patent CA-2615113-A1 (CA)
Inventor: IWASAKI YUKIKO
IPC: H04N1/00
Filed: 2007-01-11
Abstract: When photographic image quality is formed, before or after a transparent recording medium having formed thereon an image obtained by reversing an original image is conveyed through the conveyor path, a non-transparent white recording medium is conveyed through the conveyor path, and the reversed image is formed on the transparent recording medium. During conveyance before or after a post-process, such as a fixing process, conveyance of a non-transparent medium is started. Then, the transparent recording medium 121 is arranged to interpose the reversed toner image, functioning as a reflecting plate from the back with respect to the reversed toner image 122. Then, before or after the transparent recording medium having formed thereon the reversed image is delivered to the outside of the apparatus, the non-transparent medium is delivered downward or upward. At this time, the transparent recording medium and the non-transparent medium are superposed each other in a state such that a toner image formed on the transparent recording medium is interposed therebetween.
Patent CA-2615553-A1 (CA)
Inventor: MARUI KEIZO
IPC: H04Q7/32
Filed: 2007-12-20
Abstract: A graphical indicator, menu and method for modifying and displaying more than two states for the indicator is provided. An alarm indicator algorithm modifies and displays the indicator according to user-selectable options that enables a user to determine at first glance the nature of the next alarm and in particular when an alarm is not set to go off on a particular day to avoid accessing the alarm menu every time this knowledge is desired or whenever the user is uncertain of the settings. Various visual cues such as colour, graphical and textual elements can be used and the algorithm can associate these cues with appropriate alarm states.  When the number of settings for the multi-state alarm is relatively large, a desktop web-based application program interface (API) may be used to facilitate setting and updating the alarm functions.
Patent CA-2615871-A1 (CA)
Inventor: WAISANEN STEVEN K
IPC: B66C17/00
Filed: 2005-07-21
Abstract: An overhead crane adapted to be supported by at least one main support beam includes a bridge adapted to travel in a substantially horizontal direction along the at least one main support beam, a trolley adapted to travel in a substantially horizontal direction along the bridge, a jib rotatably coupled to a bottom surface of the trolley, and a hoist adapted to travel in a substantially horizontal direction along the jib.
Patent CA-2615964-A1 (CA)
Inventor: HART KELLY DENISE
IPC: A61K8/891
Filed: 2006-12-12
Abstract: A cosmetic water-in-oil composition is provided which includes a water-in-oil emulsifying silicone surfactant, crosslinked silicone elastomer and conjugated linoleic acid. The conjugated linoleic acid functions to improve radiance on facial surfaces to which the composition is topically applied.
Patent CA-2616262-A1 (CA)
Title: Mobile nitrogen generation device
Inventor: KEITH MICHAEL J
IPC: B01D53/22
Filed: 2006-07-19
Abstract: A mobile inert gas generator can include various components supported by a wheeled vehicle. The generator can include a feed air compressor, a separation device for separating an inert gas from a feed air gas, and a booster compressor, each of which can have various sensors and actuators for controlling the operation thereof. An electronic control system can be connected to the sensors and actuators to allow for convenient operation of the generator. The electronic control system can include a control panel disposed in a cab.
Patent CA-2616363-A1 (CA)
Title: Coding device, coding method, decoding device, decoding method, and programs of same
Inventor: LEE HUNG-JU
IPC: G06K9/40
Filed: 2006-04-04
Abstract: A coding device (2) have a specifying unit for specifying image region data to be processed for refreshing countermeasures i image data being coded based on that image data and a refreshing countermeasure unit (54) for applying processing for refreshing countermeasures to image region data specified by the specifying unit when coding the image data.
Patent CA-2616402-A1 (CA)
Inventor: HUANG DIJIA
IPC: G01N33/487
Filed: 2006-07-24
Abstract: A method of operating a meter for determining the concentration of an analyte in a current sample and for self-detecting electrical connection errors like short or open circuit between the electrodes of a biosensor. The method includes providing a connector with a plurality of contacts and coupling each of the plurality of contacts to one of a plurality of electrical leads on a biosensor, such that each of the plurality of connector contacts electrically contacts a corresponding one of the plurality of electrical leads. The meter obtains a first measurement between a pair of the plurality of connector contacts prior to the fluid sample being applied. The meter also obtains a second measurement between the pair of the plurality of connector contacts after the fluid sample is applied. In response to either the first or the second measurements being outside a predetermined range, a fault is indicated.
Patent CA-2620269-A1 (CA)
Title: 3,5-disubstituted pyrid-2-ones useful as inhibitors of tec family of non-receptor tyrosine kinases
Inventor: DURRANT STEVEN
IPC: A61P35/00
Filed: 2006-08-29
Abstract: The present invention relates to pyrid-2-one compounds of formula (I) useful as inhibitors of Tec family (e.g. Tec, Btk, Itk/emt/Tsk, Bmx, Txk/Rlk) protein kinases. These compounds and pharmaceutically acceptable compositions thereof are useful for treating or preventing autoimmune, inflammatory, proliferative, hyperproliferative or immunologically-mediated diseases, wherein R2' is a ring; Q is 5-membered heteroaryl containing 1-4 nitrogen atoms, wherin one of the nitrogen atoms is NH; each Q is optionally substituted with 0-3 JQ and is optionally fused to ring Q1; each R3 and R4 is as described herein (Formula I).
Patent CA-2620456-A1 (CA)
Title: Method for production, substitution, or mining of gas hydrate
Inventor: IKEGAWA YOJIRO
IPC: C07C9/04
Filed: 2006-08-25
Abstract: A gas hydrate is produced by microparticulating a liquid guest molecule into a microparticle smaller than a narrow space in the strata, dispersing the microparticle in water to give an emulsion, and injecting the emulsion into the narrow space under such temperature/pressure conditions that the guest molecule can be converted into a hydrate, thereby dispersing the guest molecule uniformly in the narrow space in the strata and forming a gas hydrate.