Patent SG-11201810117W-A (SG)
Title: Human platelet lysate derived extracellular vesicles for use in medicine
Inventor: DE MIROSCHEDJI KYRA NATALIA MATAHARI
IPC: A61K35/19
Filed: 2017-06-07
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1111111111111011101111111111111111111111111111111111111111111111111111111111111111110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2017/211906 Al 14 December 2017 (14.12.2017) WIP0 I PCT (51) International Patent Classification: A61K 35/19 (2015.01) A61M 1/00 (2006.01) (21) International Application Number: PCT/EP2017/063868 (22) International Filing Date: 07 June 2017 (07.06.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 16173465.2 08 June 2016 (08.06.2016) EP (72) Inventor; and (71) Applicant: DE MIROSCHEDJI, Kyra Natalia Matahari [DE/DE]; Wiedfeldtstr. 60A, 45133 Essen (DE). (74) Agent: DTS PATENT- UND RECHTSANWALTE SCHNEKENBUHL UND PARTNER MBB; St.-An- na-Str. 15, 80538 Miinchen (DE). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, — = = DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. _ = = (84) Designated States (unless otherwise indicated, for every = kind of regional protection available): ARIPO (BW, GH, = GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, = = UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, = TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, = EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, = = KM, ML, MR, NE, SN, TD, TG). = = Published: = — with international search report (Art. 21(3)) 1-1 ..! (54) Title: HUMAN PLATELET LYSATE DERIVED EXTRACELLULAR VESICLES FOR USE IN MEDICINE (57) : The present invention is related to human platelet lysate or a fraction that is enriched for human platelet lysate de- t:N rived extracellular vesicles and their use in medicine, particularly for the prevention and/or treatment of inflammatory driven diseases, 1 -1 neurodegenerative diseases, immune/autoimmune diseases, cardiovascular diseases, dermatologic diseases, orthopedic diseases, tissue 1-1 regenerative medicine, oncologic diseases, infectious diseases, transplant rejections, stroke, ischemia or Graft-versus-Host Disease. ei --.... The present invention is further related to a method of manufacture of a pharmaceutical preparation or a diagnostic preparation or a IN cosmetic preparation comprising the step of adding human platelet lysate or a fraction that is enriched for human platelet lysate derived 1-1 C extracellular vesicles to the pharmaceutical preparation or a diagnostic preparation or a cosmetic preparation. ei C