baber/WOPTO huggingface dataset:
Patent EP-2892898-A1 (EP)
Inventor: THIBEAULT CARL
IPC: A61K31/438
Filed: 2013-07-30
Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are antagonists of Ρ2Y 1  receptor and may be used as medicaments in the treatment and/or prophylaxis of thromboembolic disorders.
Patent EP-2812686-A1 (EP)
Title: Plateforme de criblage de métabolites par rmn
Inventor: O'DAY ELIZABETH M
IPC: B01D59/44
Filed: 2013-02-11
Abstract: Cette invention concerne des procédés qui permettent de mesurer spécifiquement le produit métabolique d'une molécule particulière dans relativement peu de cellules, par ex, des cellules primaires. Les procédés selon l'invention impliquent éventuellement le préchargement des cellules avec un substrat marqué (par ex., marqué par  13 C,  15 N, ou  31 P) et permettent l'identification facile des métabolites qui sont générés différentiellement dans des cellules de phénotypes différents. Les nouveaux procédés de criblage RMN multidimensionnels non biaisés et l'analyse rapide et efficace du criblage RMN selon l'invention identifient des métabolites exprimés différentiellement dans différents types de cellules ou de tissus. L'analyse des métabolites exprimés différentiellement peut donner des cibles pharmacopotentielles uniques pour lesquelles des agents thérapeutiques à petites molécules peuvent être conçus.
Patent EP-2880201-A1 (EP)
Inventor: GOODWIN FREDERICK R
IPC: E04G23/02
Filed: 2013-07-30
Abstract: L'invention concerne une anode galvanique sacrificielle, un ensemble anodique comprenant l'anode sacrificielle, et un procédé de protection cathodique de renfort d'acier dans des structures de béton contre la corrosion. L'anode galvanique sacrificielle comprend au moins une bobine hélicoïdale métallique sacrificielle. L'anode galvanique est fabriquée facilement et occupe un volume minimal dans une structure de béton à renfort d'acier, tout en fournissant une surface maximale pour une corrosion sacrificielle.
Patent EP-2814837-A1 (EP)
Title: Antigènes largement réactifs optimisés par ordinateur pour la grippe h5n1 humaine et aviaire
Inventor: ROSS TED M
IPC: C07K14/11
Filed: 2013-02-08
Abstract: La présente invention concerne la génération de polypeptides HA de la grippe H5N1 optimisés pour obtenir une réponse immunitaire largement réactive vis-à-vis d'isolats du virus de la grippe H5N1. Des polypeptides HA optimisés ont été développés par l'intermédiaire d'une série d'alignements de protéine HA et la génération ultérieure de séquences consensus, sur la base d'isolats de H5N1 humain et aviaire. La présente invention concerne des polypeptides HA de H5N1 optimisés, et des compositions, des protéines de fusion et des VLP comprenant les polypeptides HA. L'invention concerne en outre des séquences d'acide nucléique optimisées par un codon codant pour les polypeptides HA. La présente invention concerne également des procédés d'obtention d'une réponse immunitaire dirigée contre le virus de la grippe chez un sujet.
Patent EP-2883246-A1 (EP)
Inventor: VAN KAMPEN ROBERTUS PETRUS
IPC: H01L49/02
Filed: 2013-08-07
Abstract: A variable capacitor (300) comprises cells (200, 400) that have an RF electrode (202, 402) coupled to a bond pad (30). Each cell comprises a plurality of MEMS devices (100) the capacitance of which can be changed by means of a movable electrode. The MEMS devices are placed in a sealed cavity of the cell and are arranged next to each other along the length of the RF electrode of the cell. The RF electrode of each cell can be trimmed so as to obtain an RF line (402) and a further ground electrode (404) and so as to scale the RF capacitance of the cell without impacting the mechanical performance of the MEMS cells. Each cell has the same control capacitance irrespective of the RF capacitance. This allows each cell to use the same isolation resistor required for RF operation and thus each cell has the same parasitic capacitance. This allows the CMOS control circuit to be optimized and the dynamic performance of the cells to be matched.
Patent EP-2818884-A1 (EP)
Inventor: DEAK JAMES GEZA
IPC: G01R33/09
Filed: 2013-02-19
Abstract: The present invention relates to a magnetoresistive sensor for measuring a magnetic field. A calculation of the sensitivity to external magnetic fields is provided, and it is shown to be related to the shape anisotropy of the magnetoresistive sensing elements. Moreover, it is shown that sensitivity may be made highest when the shape of the magnetoresistive element is long parallel to the sensing axis, and a magnetic bias field strong enough to saturate the magnetoresistive element's magnetization, H cross , is applied perpendicular to the sensing axis. A monolithic permanent magnet is provided to generate the H cross  and it may be applied at an angle in order to counteract non-ideal fields along the sense axis direction. The high sensitivity magnetoresistive element can be used in many electrical form-factors. Six exemplary bridge configurations are described herein.
Patent EP-2890231-A1 (EP)
Inventor: SAAB IMAD N
IPC: A01C1/02
Filed: 2013-08-28
Abstract: The present invention provides methods for testing seed germination and predicting seed emergence in stressful field conditions, such as cold and flooding stress. Cold Soak Test and ultra-drying methods are provided herein. The methods find use in the development of corn breeding technologies and germplasm selection to evaluate and develop new hybrids that can produce stable stands under stressful field conditions.
Patent EP-2890449-A1 (EP)
Inventor: OSORIO IVAN
IPC: A61N1/36
Filed: 2013-08-22
Abstract: Disclosed are methods and systems for treating epilepsy by stimulating a main trunk of a vagus nerve, or a left vagus nerve, when the patient has had no seizure or a seizure that is not characterized by cardiac changes such as an increase in heart rate, and stimulating a cardiac branch of a vagus nerve, or a right vagus nerve, when the patient has had a seizure characterized by cardiac changes such as a heart rate increase.
Patent EP-2898014-A1 (EP)
Inventor: HERKLOTS MARC
IPC: C08L23/14
Filed: 2013-09-17
Abstract: The invention relates to a process for the preparation of a composition comprising a heterophasic propylene copolymer, a propylene copolymer and talc, wherein the heterophasic propylene copolymer consists of (a) a propylene-based matrix, wherein the propylene-based matrix consists of a propylene homopolymer and/or a propylene- α-olefin copolymer consisting of at least 70% by mass of propylene and up to 30% by mass of α-olefin based on the total mass of the propylene-based matrix, wherein the propylene-based matrix is present in an amount of 60 to 95wt% based on the total heterophasic propylene copolymer and (b) a dispersed ethylene-α-olefin copolymer, wherein the dispersed ethylene-α-olefin copolymer is present in an amount of 40 to 5wt% based on the total heterophasic propylene copolymer and wherein the sum of the total amount of propylene-based matrix and total amount of the dispersed ethylene-α-olefin copolymer in the heterophasic propylene copolymer is 00wt%, wherein the composition has a desired melt flow index in the range of 1 to 200dg/min as measured according to ISO1133 (2.16 kg/230°C) comprising the steps of (a) melt-mixing a propylene copolymer with a talc to obtain a masterbatch (b) melt-mixing the masterbatch with 1 the heterophasic propylene copolymer and a peroxide to obtain the composition comprising a heterophasic propylene copolymer, a propylene copolymer and talc, wherein the amount of peroxide is chosen such that a composition comprising a heterophasic propylene copolymer, a propylene copolymer and talc having the desired melt flow index is obtained.
Patent EP-2836735-A1 (EP)
Inventor: GILBERT BENOÎT
IPC: B25J9/12
Filed: 2013-03-21
Abstract: A torque limiting assembly for use with an actuator having a torque transfer output, the assembly comprising a brake pad, a band connected at a first extremity to a first extremity of the brake pad and a cam linking a second extremity of the band to a second extremity of the brake pad. The brake pad and the band are configured to wrap around the a torque transfer output and the positioning of the cam in a first position frictionally engages the brake pad and the band with the a torque transfer output while the positioning of the cam in a second position disengages the brake pad and the band with the a torque transfer output.
Patent EP-2831044-A1 (EP)
Title: Méthodes de préparation de 6-(trifluorométhyl)pyridines 3-substituées et méthodes d'utilisation de 6-(trichlorométhyl)pyridines halogénées
Inventor: ROSS RONALD
IPC: C07D213/26
Filed: 2013-03-15
Abstract: Les 6-(trifluorométhyl)pyridines 3-substituées de l'invention sont des intermédiaires de synthèse utiles dans la préparation de (6-haloalkylpyridin-3-yl)alkyl sulfoximines n substituées utilisables dans la production d'insecticides puissants. On décrit des méthodes de production desdites 6-(trifluorométhyl)pyridines 3-substituées. On décrit en outre des méthodes d'utilisation de 6-(trichlorométhyl)pyridines halogénées pour produire des 6-(trifluorométhyl)pyridines 3-substituées.
Patent EP-2761730-A1 (EP)
Inventor: KALEV CLAUDE MICHAEL
IPC: H02K7/02
Filed: 2013-03-22
Abstract: L'invention concerne un volant d'inertie électromécanique à système d'évacuation. Ce volant comporte : une masse de volant d'inertie à l'intérieur d'un logement à évacuation ; un train d'élimination du gaz extérieur au logement à évacuation, ce train comprenant une pompe à vide mécanique et un dispositif non mécanique d'élimination du gaz ; une substance capable d'adsorption et une substance de tamis moléculaire dans le boîtier du dispositif d'élimination du gaz, le train ayant pour fonction de se coupler fluidiquement au boîtier et au logement à évacuation de façon à faire baisser la pression intérieure du logement à évacuation ; un capteur de pression configuré pour détecter la pression intérieure du logement à évacuation, la pompe étant configurée pour fonctionner en mode discontinu en fonction des écarts entre une pression détectée par le capteur de pression et un seuil de dépression.
Patent EP-2901494-A1 (EP)
Inventor: THOMP SON MARK E
IPC: H01L31/055
Filed: 2013-09-26
Abstract: The present disclosure relates to a photosensitive optoelectronic device comprising two electrodes, an inorganic subcell positioned between the two electrodes, wherein the inorganic subcell comprises at least one inorganic semiconductor material having a band gap energy (EG), and an organic sensitizing window layer disposed on the inorganic subcell. In one aspect, the organic sensitizing window layer comprises a singlet fission material. In another aspect, the organic sensitizing window layer comprises a singlet fission host and a phosphorescent emitter dopant, where the singlet fission host exhibits an excitation triplet energy (ET-SF) greater than or equal to an excitation triplet energy (ET-PE) exhibited by the phosphorescent emitter dopant.
Patent EP-2857764-A1 (EP)
Inventor: TERAKI JUNICHI
IPC: H05K7/20
Filed: 2013-04-26
Abstract: A printed board (51) on which a power module (53) is mounted, a cooling pipe (15) that is a refrigerant pipe of a refrigerant circuit, and a cooler (60) attached to the power module (53) and the cooling pipe (15) are disposed in a casing (40). A support member (63) by which the cooler (60) is attached to the printed board (51) and supported on the printed board (51), and a fixing member (55) by which the printed board (51) is fixed to the casing (40) and supported on the casing (40) are used.
Patent EP-2872549-A1 (EP)
Title: Films d'emballage pour adhésifs thermofusibles en une seule pièce et leur utilisation
Inventor: CHEN JINYU
IPC: C08L23/04
Filed: 2013-05-02
Abstract: L'invention concerne des films d'emballage, à base de polymère de propylène, destinés à l'encapsulation d'adhésifs thermofusibles. Les films d'emballage sont facilement miscibles avec divers produits chimiques adhésifs thermofusibles lors de l'étape de fusion sans influencer de manière nuisible les propriétés adhésives, rendant le film d'emballage particulièrement bien approprié à l'emballage d'adhésifs thermofusibles dans un coussin, un cylindre, un sachet, un bloc, une cartouche et d'autres formes analogues.
Patent EP-2849567-A1 (EP)
Inventor: SOLIMAN TARIK M
IPC: A61K47/48
Filed: 2013-03-14
Abstract: The invention provides carriers that enhance the absorption, half-life or bioavailability of therapeutic compounds. The carriers comprise targeting groups that bind the Vitamin D Binding protein (DBP), conjugation groups for coupling the targeting groups to the therapeutic compounds, and optionally scaffolding moieties.
Patent EP-2866395-A1 (EP)
Inventor: ZHANG YABING
IPC: H04L47/36
Filed: 2013-06-06
Abstract: Disclosed are a maximum transmission unit (MTU) negotiation method and a data terminal. The method comprises: a data terminal receiving a first request message sent by a user terminal during establishment of a communication protocol link and carrying an MTU of the user terminal; updating the MTU of the user terminal carried in the first request message to be a path MTU; sending a second request message carrying the path MTU to a server; receiving a first reply message returned by the server and carrying an MTU of the server; updating the MTU of the server carried in the first reply message to be the path MTU; and sending a second reply message carrying the path MTU to the user terminal. The method and data terminal provided by the present invention can improve network performance.
Patent EP-2852391-A1 (EP)
Inventor: PERKINS WALTER
IPC: A61K9/127
Filed: 2013-05-21
Abstract: Provided herein are systems for treating a subject with a pulmonary infection, for example, a nontuberculous mycobacterial pulmonary infection, a Burkholderia pulmonary infection, a pulmonary infection associated with bronchiectasis, or a Pseudomonas pulmonary infection. The system includes a pharmaceutical formulation comprising a liposomal aminoglycoside dispersion, and the lipid component of the liposomes consist essentially of electrically neutral lipids. The system also includes a nebulizer which generates an aerosol of the pharmaceutical formulation at a rate greater than about 0.53 gram per minute. The aerosol is delivered to the subject via inhalation for the treatment of the pulmonary infection.
Patent EP-2853786-A1 (EP)
Inventor: INOUE HIDEYUKI
IPC: F16C33/74
Filed: 2013-05-15
Abstract: {Technical Problem} Provide a sliding component that reduces the leakage rate of sealed fluid and significantly improves the lubrication characteristics at startup or stop, while being actuated by means of fluid lubrication in the rotation phase, thereby achieving the effects of sealing and lubrication at the same time. 
     {Solution to Problem} The sliding component is characterized in that: on one sealing face of a pair of sliding parts that slide relative to each other, multiple positive pressure-generating mechanisms that comprise extremely shallow parallel grooves running roughly in parallel with the sealing face and having submicron-level height differences are provided independently in the circumferential direction; extremely shallow thin grooves are formed on the sealing face on the low-pressure fluid side of the extremely shallow parallel grooves; the extremely shallow parallel grooves communicate with the high-pressure fluid side; and the extremely shallow thin grooves communicate with the extremely shallow parallel grooves, but are isolated from the low-pressure fluid side by a seal area.
Patent EP-2853030-A1 (EP)
Title: Intégrateur numérique de faible puissance et compact pour détecteur de phase numérique
Inventor: NGUYEN THE LINH
IPC: H03L7/093
Filed: 2013-05-17
Abstract: Un exemple de mode de réalisation de l'invention porte sur un circuit de boucle à verrouillage de phase qui peut comprendre une première circuiterie qui reçoit un signal de référence et un signal source. La première circuiterie peut générer un signal de correction servant à représenter une différence de phase entre le signal de référence et le signal source. La boucle à verrouillage de phase peut comprendre une deuxième circuiterie qui reçoit le signal de correction. La deuxième circuiterie peut générer un signal numérique servant à représenter une conversion phase-numérique du signal de correction. La boucle à verrouillage de phase peut comprendre une troisième circuiterie qui reçoit le signal numérique. La troisième circuiterie peut générer un signal de commande servant à représenter une tension convertie du signal numérique. La boucle à verrouillage de phase peut comprendre une quatrième circuiterie qui reçoit le signal de commande. La quatrième circuiterie peut générer le signal source en réponse au signal de commande.
Patent EP-2893665-A1 (EP)
Inventor: GUO SHIGUANG
IPC: H04L5/00
Filed: 2013-09-04
Abstract: Feedback information is conveyed between a wireless device and a base station in a cellular communications network via selection and detection of radio resources utilized for an uplink reference signal transmitted from a wireless device to a base station. In this manner, additional feedback information may be sent from the wireless device to the base station without sacrificing any bandwidth available for data transfer between the wireless device and the base station. The radio resources utilized for the uplink reference signal may include cyclic shift and/or time and frequency resources. The uplink reference signal may be an uplink sounding reference signal for a long term evolution network (LTE), or its evolution, such as LTE-Advanced.
Patent EP-2839481-A1 (EP)
Inventor: ULLMANN JULIUS M
IPC: G21C15/243
Filed: 2013-03-06
Abstract: A nuclear reactor has a core installed on a lower core plate and formed from multiple fuel assemblies, each fuel assembly including a structural cage assembly. The structural cage assembly has an upper end fitting, mid grids, and a lower end fitting (LEF). The LEF positions the fuel assembly using four locating pins located at each corner of the LEF. The pins position the fuel assembly laterally by mating with receiving holes in the lower core plate. The locating pins have a chamfered tip with a flat end. The chamfered tip allows for a greater positioning margin when installing the fuel assembly in the core by guiding the pins into holes in the lower core plate, and the flat tip provides strength and stability in case the assembly is inadvertently rested on the tip of the pin instead of the LEF pads.
Patent EP-2936263-A1 (EP)
Inventor: BETTENCOURT JOHN P
IPC: H03F3/193
Filed: 2013-11-19
Abstract: A current mirror circuit having formed in a semiconductor: a pair of transistors arranged to produce an output current through an output one of the transistors proportional to a reference current fed to an input one of the pair of transistors; a resistor comprising a pair of spaced electrodes in ohmic contact with the semiconductor, one of such pair of electrodes of the resistor being coupled to the input one of the pair of transistors; and circuitry for producing a voltage across the pair of electrodes of the resistor, such circuitry placing the resistor into saturation producing current through a region in the semiconductor between the pair of spaced ohmic contacts, such produced current being fed to the input one of the transistors as the reference current for the current mirror.
Patent EP-2914193-A1 (EP)
Inventor: BEAN DAVID M
IPC: A61B18/20
Filed: 2013-10-29
Abstract: A method for providing localized heating of the dermal layers of skin of a patient, using energy in the form of a group of pulses having defined parameters in a controlled manner. This method preferably uses an optical delivery system to deliver pulsed energy to a specific spot of skin so that targeted layers of the affected skin are heated to a desired temperature range. The temperature range is optimally selected to maximize treatment efficacy while minimizing pain to the patient. Example applications include reducing wrinkles, acne, hair, scar tissue, warts, and promoting wound healing. In this method, the temperature of the selected locus rises quickly to the desired temperature range, then is maintained within a controlled range with a relatively flat temperature profile. The method maintains the temperature by controlling one or more of a pulse energy intensity, pulse width, and pulse frequency or time delay between pulses.
Patent EP-2932175-A1 (EP)
Inventor: ALT RENÉ
IPC: F25D25/02
Filed: 2013-12-09
Abstract: The invention relates to a refrigeration appliance comprising a refrigeration compartment in which a shelf (110) and a bottle holder (200) are arranged. The bottle holder (200) is secured to the shelf (110) and includes a bottle support (210) which can be moved between an operational position (II) and an non-operational position (I). According to the invention, the bottle support (210) is rigidly connected to a guided section (222) which is guided in a guide (208) of the bottle holder (200).
Patent EP-2873678-A1 (EP)
Inventor: KIM SANG JAE
IPC: A61K47/48
Filed: 2013-07-11
Abstract: The present invention relates to a conjugate of cell penetrating peptide and an active ingredient; and its use. Specifically, a conjugate including a cell penetrating peptide which is a peptide comprising amino acid sequence of SEQ ID NO:1, a fragment of any one sequence of SEQ ID NO:1, or a peptide having above 80% homology with the above-mentioned sequence; and a composition comprising the same are disclosed.
Patent EP-2936358-A1 (EP)
Title: Prédiction de bioactivation moléculaire
Inventor: FORD KEVIN A
IPC: G06F19/00
Filed: 2013-12-17
Abstract: La présente invention concerne des procédés permettant de prédire la bioactivation moléculaire, la réactivité et la toxicité de composés et de leurs métabolites.
Patent EP-2894416-A1 (EP)
Inventor: SHIN YOON MIN
IPC: F24H9/20
Filed: 2013-07-12
Abstract: The present invention relates to a hot-water boiler, which is particularly aimed to improve thermal conduction efficiency and thus to save energy by increasing the heating speed of hot water and facilitating the flow of hot water at the same time. The present invention is characterized by inducing and discharging air to the upper side of a raw water tank, and heating raw water and returning water while the raw water and the returning water fill at least 95% of the inside of a penetration section and an adaptor section, thereby significantly improving the internal expansion force. The heating pipes of the present invention are extrusion molded to have a hot-water pathway section in the inside thereof, wherein the hot-water pathway section can be of a semi-elliptical, rectangular, triangular, or circular shape, and is formed integrally with a sensible heat section having a flat plate shape, on both ends of the top surface thereof, and wherein an insulation section, which has an air layer at the outer circumference of the lower part of the hot-water pathway section, is formed such that the top ends are integral with the sensible heat section.
Patent EP-2894346-A1 (EP)
Inventor: YAMATO YUKIO
IPC: H05K7/20
Filed: 2013-08-27
Abstract: A molecular pump (1A) includes a pump body (2) provided with a turbo molecular pump portion (2a), a control unit (4) provided with a control portion and a power supply portion, and a cooling unit (3) for cooling the pump body (2) and the control unit (4). A first temperature detecting portion (90) is provided in a first position, which is a position inside the control unit (4) and has a low temperature. A second temperature detecting portion (80) also serving as a humidity detecting portion is provided in a second position, which is a position inside the control unit (4) and has a high temperature. The control portion controls the operation of the cooling unit (3) in accordance with a relative humidity in the first position, calculated based on temperature information detected by the first temperature detecting portion (90) and based on temperature information and humidity information detected by the second temperature detecting portion (80) also serving as a humidity detecting portion.