baber/WOPTO huggingface dataset:
Patent EC-SP034493-A (EC)
Title: Inhibidores de proteasa peptidomimeticos
Inventor: BABINE ROBERT EDWARD
IPC: C07D403/00
Filed: 2003-02-25
Abstract: La presente invención se refiere a compuestos péptido miméticos útiles como inhibidores de proteasa (1), en particular como inhibidores de serina proteasa y más particularmente como inhibidores de la proteasa NS3 de la hepatitis C; a intermedios de los mismos; a su preparación incluyendo nuevos procedimientos estereaselectivos para los intermedios. La invención también se refiere a composiciones farmacéuticas y a procedimientos para usar los compuestos para inhibir la proteasa del HCV o tratar un paciente que padece una infección por HCV o estados fisiológicos relacionados con la infección. Además se proporcionan combinaciones farmacéuticas que comprenden, además de uno o más inhibidores de serina proteasa del HCV, uno o más interferones que presentan actividad frente al HCV y/o uno o más compuestos que tienen actividad frente al HCV y un vehículo farmacéuticamente aceptable y procedimientos para tratar o prevenir una infección por HCV en un paciente usando las composiciones. La presente invención también se refiere a un kit o envase farmacéutico para tratar o prevenir una infección por HCV en un paciente.
Patent EC-SP045490-A (EC)
Title: Uso de pulullan como un carbohidrato de digestion lenta
IPC: A23L29/269
Filed: 2004-12-10
Abstract: La presente invención esta dirigida al descubrimiento de un nuevo carbohidratos de digestión lenta, pululan, y a su empleo en el manejo dietético de la diabetes y a los alimentos que contienen pululan.
Patent EC-SP109858-A (EC)
Title: Producción de recursos utilizando inyección de fluido calentado
Inventor: SCHULTZ ROGER L
IPC: E21B34/08
Filed: 2010-01-06
Abstract: Un sistema para tratar una zona subterránea (110) incluye un calentador de fluido ubicado en el fondo del pozo (120) instalado en un pozo (114). Los conductos de fluido de tratamiento, oxidante y combustible (124a, 124b y 124c) conectan las fuentes de combustible, oxidante y fluido de tratamiento (142a, 142b y 142c) con el calentador de fluido del fondo del pozo (120). Una válvula de control de combustible del fondo del pozo (126c) está en comunicación con el conducto de combustible (124c) y se configura para cambiar el flujo destinado al calentador de fluido del fondo del pozo (120) en respuesta a un cambio de presión en una porción del pozo.
Patent EC-SP972098-A (EC)
Title: Complejos de inclusion de sales de aril meterociclicos
Inventor: SHANKER RAVI MYSORE
IPC: A61K31/496
Filed: 1997-04-28
Abstract: Composiciones de materia que contienen una sal farmacéuticamente aceptable de un compuesto aril-heterocíclico, tal como la ziprasidona en una ciclodextrina. Las iclodextrinas preferidas son la SBECD y la HPBCD. La composición puede contener una mezcla seca, un complejo de inclusión seco o una solución acuosa. El complejo de inclusión sal/ciclodextrina proporciona preferentemente una cantidad de ziprasidona de al menos 2,5 mgA/ml cuando el complejo se disuelve en agua 40% p/v. Se prefieren varias sales de ziprasidona, incluyendo el mesilato, esilato, bensilato, tartrato, napsilato y tosilato.
Patent EC-SP982434-A (EC)
Title: Quinoxalinadionas
Inventor: GAUTIER ELISABETH COLETTE LOUISE
IPC: A61K31/49
Filed: 1998-02-27
Abstract: La presente invención proporciona un compuesto sustancialmente puro de fórmula: o una sal o solvato farmacéuticamente aceptable del mismo, junto con composiciones que contienen, usos de, procedimientos para la preparación de, intermedios usados en la preparación.
Patent EC-SP993197-A (EC)
Title: Formulacion medicamentosa acuosa para administracion oral (caso lea 32857-ec)
Inventor: SIEFERT HANS-MARTIN
IPC: A61K31/49
Filed: 1999-10-29
Abstract: La presente invención se refiere a una composición farmacéutica acuosa para uso oral que comprende un principio activo de la clase de los antibióticos ácidos quinolón o naftiridoncarboxilicos asi como al menos un ácido policarboxílico o una sal del mismo expandibles, a un procediento para su preparación asi como al uso de la misma para la fabricación de un medicamento.
Patent EE-9900531-A (EE)
Inventor: NORBERT EISEN
IPC: C08J9/14
Filed: 1998-05-08
Abstract: The invention provides a process for preparing flexible to semi-rigid polyurethane moulded items with compacted edge zones with given hardness and a much more flexible cellular core, so-called integral foams, in which physical blowing agents from the set comprising C6 hydrocarbons are used.
Patent FI-20002265-A (FI)
Inventor: KOSKELA JARI
IPC: H04M19/02
Filed: 2000-10-13
Abstract: A method and a circuit arrangement are disclosed for detecting ring trip in a subscriber line interface circuit (101, 210) coupled to a subscriber line (220) of a wireline telephone network. There is provided an amplifying output stage (102, 213, 214) for feeding a ring signal into the subscriber line (220) and a supply voltage source (104, 215, 216) for providing a supply voltage to the amplifying output stage (102, 213, 214). Additionally there is provided monitoring and detection means (105, 106, 301, 302, 303) for monitoring an electric characteristic internal to the subscriber line interface circuit, said monitoring and detection means (105, 106, 301, 302, 303) being arranged to detect a change in said electric characteristic and to give a ring trip indication on the basis of a detected change in said electric characteristic.
Patent FI-20125612-A (FI)
Inventor: KORHONEN HELGE
IPC: B66B7/02
Filed: 2012-06-05
Abstract: The object of the invention is an intermediate beam of an elevator, which beam comprises at least a frame (1) and guide rail fixing means (5, 12) fixed into connection with the frame (1). The intermediate beam of an elevator comprises separate wall fixing elements (2), which are disposed at the ends of the frame (1) of the intermediate beam and fixed into their position by means of compression.
Patent FR-1601293-A (FR)
Title: Cable with a plastic core
Inventor: RENE FALCY BERNARD MAZUIR
IPC: D07B1/16
Filed: 1968-12-31
Granted: 1970-08-10
Abstract: Cable is formed from strands wound around a core of plastic material with good mechanical properties, this core having an external profile which is complementary to the interanl profile of the strand assembly supported by the core. The core pref. consists of polyethylene, polypropylene or a polyamide. The cable has an excellent dimensional stability.
Patent GB-1051367-A (GB)
IPC: B29C48/03
Abstract: 1,051,367. Extruding thermoplastic materials. DYNA-PLASTIK-WERK G.m.b.H. June 9, 1964 [July 4, 1963], No. 23924/64. Heading B5A. Thermoplastic plastics material passing through an extruder is homogenized by one or more moving body or bodies disposed between the extrusion screw and the nozzle and rotating and/or oscillating about an axis transverse to the axis of the screw. An extruder is described in which the homogenization is effected by a rotating ball.
Patent GB-1051376-A (GB)
IPC: B61D1/08
Abstract: 1,051,376. Railway carriages. COMPAGNIE INTERNATIONALE DES WAGONS-LIT ET DES GRANDS EXPRESS EUROPEENS. Nov. 3, 1964 [Nov. 4, 19631, No. 44793/64. Heading B7C. A sleeping car has alternately along its length lower and upper compartments 1, 15, Fig. 1, of L- and T-shaped section, respectively, the floors 2 of the compartments 1 being level with the floor of the corridor 3, Fig. 3 (not shown), whilst the floors 14 of the compartments 15 are at a higher level and are each connected to the corridor 3 by at least one step 16, Fig. 2. Each compartment 1 has folding beds 8, 9, stowable against one wall, seats 6, 7 which are stowable under the bed 8, when erected, an air conditioning device 12, a washstand 10 and a luggage boot 13 under the floor 14 of the adjacent compartment 15. Each compartment 15 has beds 22, 23 disposed on the ceilings of the adjacent compartments 1, a double seat 19, an air-conditioning device 21, a washstand 20 and a luggage boot 24 above the beds and provided with an extension 25 connected to the car roof by the rods.
Patent GB-1052019-A (GB)
IPC: G03G21/00
Abstract: 1,052,019. Cleaning electrophotographic plates. L. F.W. LAWES, N. G. SHREEVE and N. MIHALIK. June 16, 1965 [March 16, 1964], No. 10933/64. Heading G2H. Surfaces carrying developed electrostatic images are cleaned by brushes 2, 3, 4 engaging flick - edges 5, 6 and 7 which discharge powder, picked up by the brushes, into a chamber 20. A removable slide 9 Fig. 2 (not shown) of insulating material retains powder by electrostatic force. Alternatively the chamber 20 may be connected to a fan 11 Fig. 3 (not shown) which draws powder laden air through a filter 12. In another embodiment, Fig. 4 (not shown) an electrostatic precipitator cleans discharged air.
Patent GB-1225529-A (GB)
IPC: B22D45/00
Filed: 1968-11-09
Abstract: 1,225,529. Foundry plant. BRITISH MOTOR CORP. Ltd. 15 Oct., 1969 [9 Nov., 1968], No. 53201/68. Heading B3F. An apparatus for conveying and mounting a shell mould 20 in a flask 6 comprises two pairs of horizontal rails 4, 5 arranged to form upper and lower tracks upon which the flasks 6 run on rollers 7. At each end of the track is an automatic lift 8, 9. These lifts operate synchronously. Separate means 22, 25 move the flasks 6 along the tracks in an indexing manner. A flask at the left-hand end of the lower track is raised by the lift 8 to the upper track. During the raising, air is supplied to the porous base 14 of the flask to fluidize a bed of sand in the flask. The shell mould 20 is taken from a furnace (not shown) by a mechanical handler 21 and lowered into the fluidized sand bed. The fluidization is stopped and the shell mould firmly held in its flask by the sand. The mouldcontaining flask is moved rightwards to a casting and an extraction station. The last flask on the upper track is pushed on to a lift 9 and lowered to the lower track for return to the fluidization station.
Patent GB-1226066-A (GB)
IPC: B65D65/40
Filed: 1969-05-20
Abstract: 1,226,066. Laminated paperboard. STONE CONTAINER CORP. 20 May, 1969, No. 25707/69. Heading B5N. [Also in Division D2] The abrasiveness of paperboard for packaging is reduced by impregnating its surface with a softening and lubricating agent and raising a nap by brushing. These two steps may be carried out in either order on a double-faced corrugated board, or on one or both of two sheets which are subsequently combined as facing sheets with a corrugated sheet to form such a board with the treated face or faces turned outwards. Softening and lubricating agents referred to are waxes, stearates and silicones.
Patent GB-1226611-A (GB)
IPC: B23K20/06
Filed: 1968-05-02
Abstract: 1,226,611. Welding by pressure; removing weld flash; cutting by fusion. UNITED STATES STEEL CORP. 2 May, 1968 [9 May, 1967], No. 20954/68. Headings B3L, B3R and B3V. Apparatus for impact welding the end of a billet 14 to an adjacent end of a continuous billet 18 while the latter is being moved through a work station 22, e.g. a rolling mill, comprises a carriage 30 movable between a billet-receiving position and a forward position (adjacent the work station), at a variable first velocity initially greater than the velocity of the continuous billet as it moves through the work station, and movable between said forward position and said billet-receiving position at a second velocity greater than said first velocity, and a billet-feeding mechanism 52, adjacent the latter position of the carriage, for positioning the leading end of the billet adjacent to the trailing end of the continuous billet, the carriage carrying means for impact welding the leading end of the billet to the trailing end of the continuous billet. The apparatus may also include a spacer mechanism 51 for spacing the billets a predetermined distance apart, a heating mechanism 70 having a double-faced torch insertable between the adjacent ends of the billets to heat the ends to a temperature slightly below the melting temperature of the metal, a flash-removal mechanism 74 (Fig. 6), and a means, e.g. a pair of cutting torches 70t (Figs. 6 and 8), for cutting a slug from the end of each billet before welding and for flame desurfacing the ends. The carriage 30 mounts a pair of fixed jaws 66 for gripping the continuous billet 18 as the carriage moves therewith and a pair of slidable jaws 68 which grip and impact the billet 14 against the continuous billet. The billet 14 may be preheated in a magazine/furnace 50 before being fed to the carriage 30 by the pushrod feed mechanism 52. Operation.-Cold billets 14 are fed by conveyer 44 through pinch rolls 46 to reheating furnace 50; heated billets are discharged from the furnace by mechanism 52 and on to conveyer 40 when the carriage 30 is in the billetreceiving position and against an extended spacer 58 (Fig. 6), of the spacer mechanism 51 on the carriage. The spacer 58 is actuated by a piston (60), (Fig. 5, not shown), operable transverse to the direction of travel of carriage 30 and in line with the heating mechanism 70. As the end 16 of billet 18 contacts spacer 58 jaws 66 grip billet 18. The drive means of carriage 30 is declutched so that the carriage moves with billet 18. A billet 14 is propelled by mechanism 52 such that its end 12 contacts spacer 58 whereupon jaws 68 grip billet 14. The spacer 58 is retracted and heating mechanism 70 is extended between the billet ends to heat them. Thereafter jaws 68 impact the billet 14 against billet 18. After welding, scarfing dies 74a close about billet 18 and the reversing movement of carriage 30 cause the dies to remove weld flash. Prior to welding, a slug may be cut from each billet by torches 70t which may use oxygen and methane. The torches 70t may preheat and remove scale from the billets prior to removing the slugs.
Patent GB-1229268-A (GB)
IPC: A24F1/22
Filed: 1968-09-24
Abstract: 1,229,268. Smokers' pipes. E. H. CALKINS. 24 Sept., 1968, No. 45353/68. Heading A2M. A smoking pipe comprises a shell having a generally vertical outer bowl 12 and generally horizontal stem portion 14, axially disposed spaced radially inwardly extending ribs 40, 44 within the outer bowl 12, an inner bowl 50 positioned within the outer bowl 12 supported against the ribs 40, 44 to define vertical spaces therebetwen around the inner bowl 50, retaining means above the inner bowl engaging the inner surfaces of the ribs to leave the vertical spaces unobstructed at the upper open end of the outer bowl 12, and resilient means between the upper end of the inner bowl and the retaining means to accommodate longitudinal expansion of the inner bowl 50 due to heat. The retaining and resilent means may comprise a screw threaded retaining ring 62 and a corrugated, spring metal, split washer 58, respectively. Air spaces existing in the grooves 42, 46 between the ribs 40, 44 connect, via a circular channel 37 in the conical bottom 32 of the bowl 12, to a plurality of small bores 35 that extend to the outer surface of the bowl 2. A smoke opening (54) in a boss 56 at the bottom of the inner bowl 50 connects the latter to a smoke passage 36 leading to a longitudinal passage 20 in the stem 14 which passage houses a tube 28 leading to a central bore 18 in a mouthpiece 16 at one end and to a threaded cartridge 26 containing saliva absorbent material 24 at its other end. The tube 28 is provided with a smoke aperture 30. Preferably, the inner bowl is formed of meerschaum or a high quality briar, and the outer bowl and the stem are formed of a synthetic plastics material. In another embodiment, Fig. 6, channels 42<SP>1</SP> (wider than the channels 42) in the outer bowl 12 are filled with strips of insulating material 70, and in a further embodiment, Fig. 7, a flexible cup 72 fills the grooves 42 and the space betwen the two bowls 12, 50.
Patent GB-1230384-A (GB)
IPC: B32B3/12
Filed: 1968-06-26
Abstract: 1,230,384. Expandable laminated cores. HONEYCOMB SYSTEMS Inc. 26 June, 1968 [27 June, 1967], No. 30503/68. Heading B5N. A method of making an expansible core for use in making a honeycomb core panel includes allowing a plurality of strips of core material of substantially constant width and substantially constant length, each having bonding material on one face at transverse areas regularly spaced along the length thereof, to free fall one after the other to a vertical lengthwise position and pressing the strips together to bond the strips at the areas having the bonding material thereon. An apparatus suitable for use in the method comprises a vertically disposed press box having spaced side walls 182, 184 for receiving free falling strips in a vertical lengthwise position, a vertically disposed faceplate 180 between said walls and at one end thereof and means for reciprocating the faceplate horizontally to apply pressure to the strips. In a preferred embodiment, a web 44 of material, e.g. impregnated paper, plastics material, aluminium, steel or copper is cut into strips by mechanism 84, the resultant strips being coated with adhesive by drum 160 and fed to press station 34. The apparatus described includes means for varying the lengths of the strips, for rejecting scrap material and for heating the adhesive.
Patent GB-1232239-A (GB)
IPC: F02B75/04
Filed: 1968-07-19
Abstract: 1,232,239. Pistons. CONTINENTAL & ENG. CORP. 19 July, 1968 [20 July, 1967], No. 34436/68. Heading F2T. A variable compression ratio piston in an I.C. engine having outer and inner relatively movable members 12, 14 as described in Specifications 1,232,063 and 1,232,238 comprises a passage 64 for directing oil from the first chamber 30 to the second chamber 32, and a secondary passage 140 for discharging oil when necessary to the crankcase, the inlet to the second chamber being provided with a valve assembly 66 which includes a valve member movable to a first position admitting oil to the second chamber in response to an increase in volume of the second chamber and movable to a second position which permits the required leakage from the second chamber through an orifice provided in the valve assembly. The valve member of the assembly 66 consists of a triangular-shaped non- return plate valve having the leakage orifice passing through its centre and operates between a seat at the end of the passage 64 and a castellated stop member 120. In a modification, Figs. 4 and 5 (not shown), the valve assembly consists of a sliding valve plug which in its lowermost position uncovers the secondary discharge passage (212) to the crankcase and in its uppermost position uncovers the leakage orifice (214).
Patent GB-1232276-A (GB)
IPC: G01N1/36
Filed: 1968-05-22
Abstract: 1,232,276. Histologic tissue receptacle. TRIANGLE BIOMEDICAL EQUIPMENT Inc. May 22, 1968, No.24437/68. Heading G2J. A histologic tissue receptacle comprises three elements, a rectangular mould, a base pan detachiably secured to the mould at one end and a top cover secured to the mould at the other end. A tissue specimen 40 is embedded in paraffin wax 41 to facilitate transportation and cutting in a microtome. In one embodiment a tissue receptacle Fig. 1 comprises an open mould 20 having interior walls which converge inwardly in a shallow V-slope which serves to secure the hardened paraffin wax body 41 and has one of its exterior side wall surfaces etched to receive a graphite type marking pencil; a base pan 30 shaped to receive either end of open mould 20 to provide a leakproof connection; a top 11 having a plurality of openings (17) Fig. 2 (not shown) for admitting and draining processing liquids, shaped to receive the other end of open mould 20, and having knobs 18 protruding from each corner to keep the top of one receptacle separate from the base pan of another receptacle when the two are placed together. The open mould 20, base pan 30 and top 11 are formed of a mouldable material, such as polypropylene, which is inert to the processing liquids. A tissue specimen 40 is placed through the open top of base pan 30, and placed on the thin heat conductive bottom wall (31) Fig.5 (not shown) having at least one small opening (36). An open ended mould 20 is then secured to the base pan and a perforated top 11 on to the other open end of the open mould 20, to form a tissue-carrying receptacle. Appropriate indecia is applied on an exterior surface of the open mould, and the receptacle is sequently immersed in various processing liquids, such as alcohol, xylene. The perforated top is then detached from the open mould, the tissue specimen repositioned on the base pan bottom (31) Fig. 5 (not shown) and liquid paraffin wax poured to a level covering the tissue specimen, and then liquid paraffin is cooled to secure the tissue specimen in a paraffin wax body. Thereafter the open mould is securely seated between microtome jaws 42, 43, Fig. 11, the base pan detached exposing the paraffin body for cutting by microtome blade 44 to provide a slice 45. The base pan 30 is repositioned on to the open mould 20 for storing. In an alternative embodiment Fig. 12 (not shown) the open mould (60) Fig. 15 (not shown) has a first integral flange (69), (Fig. 12) extending outwardly of which at least one upper surface is adapted to receive indecia marking and a second inwardly extending flange (59) Fig. 15 which serves the same purpose as the shallow V-slope in the first embodiment. The said open mould includes grooves (65 and 74), Fig. 16 (not shown), to snap fit into respective base pan and top cover; the base pan (75) Fig. 17 (not shown) is adapted to be torn along fracture grooves (83, 84) Fig. 19 (not shown) by pulling tab (82), (Fig. 12), and is provided with at least one insert filler (86), (Fig. 17) in order to form a paraffin block in a size smaller than the size of the base pan.
Patent GB-1234259-A (GB)
IPC: G03B19/18
Filed: 1968-11-20
Abstract: 1,234,259. Cine cameras; releases. K. VOCKENHUBER and R. HAUSER. Nov. 20, 1968 [Nov.20, 1967], No.55118/68. Heading G2E. A cine camera has an electric exposure control actuated by the closure of contacts 21, 22 by bridge 20, and a release 12 to actuate the camera motor, there being locking means which ensure that the release cannot be operated until contacts 21, 22 are closed and that the contacts cannot be opened until the release is inoperative. Surface 15 of spring-loaded cam 17 pivoted at 16 prevents movement of slider 13 attached to release button 12, until yoke 11 is depressed to lower surface 15. Lowering of cam surface 15 engages bridge 20 with the exposure control contacts and permits operation of the release. Bar 14 on slider 13 then prevents the return of cam 17 until the release is withdrawn. Insertion of a cable release into apertures 28, 29 cams a slider 26 against yoke 11 whereby cam 17 is held in the contact bridging position independently of release 12.