baber/WOPTO huggingface dataset:
Patent DE-69611166-D1 (DE)
Inventor: PETTERSON TORBJOERN
IPC: A01J5/00
Filed: 1996-04-25
Granted: 2001-01-11
Abstract: PCT No. PCT/SE96/00547 Sec. 371 Date Nov. 26, 1997 Sec. 102(e) Date Nov. 26, 1997 PCT Filed Apr. 25, 1996 PCT Pub. No. WO96/38035 PCT Pub. Date Dec. 5, 1996A device (1), for example a teat liner, for reception of a teat comprising an element (2), which presents a thin, flexible wall surrounding a channel for reception for said teat, wherein said wall in a direction towards the channel has an inner side and in direction from the channel an outer side. The outer side of the wall is provided with a large number of surface enlargements (3), which have such a form, size and distribution that they form obstructions to propagation of cracks on the outer side of the wall. The invention also relates to a method for the manufacture of the device.
Patent DE-69611635-D1 (DE)
Inventor: ERIKKILAE JUHA
IPC: B66C1/42
Filed: 1996-06-18
Granted: 2001-03-01
Abstract: Transport apparatus for moving an upright cylindrical object, such as a gas bottle, in an upright position from one location to another. The transport apparatus comprises a guide rail system (4) connected to the fixed structures of a building; a crab carriage (5) suspended so as to be movable on and guided by the guide rail system; a gripping and hoisting device (6) comprising a pair of gripping jaws (8) movable in a horizontal direction by means of a power means (7) and designed to grip an upright cylindrical object by a frictional hold from both sides of the object by pressing it between the gripping jaws; and a control unit (9) for controlling the transport apparatus. <IMAGE>   <IMAGE>
Patent DE-69636714-D1 (DE)
Inventor: YOKOI HARUHIKO
IPC: C07K14/535
Filed: 1996-04-26
Granted: 2007-01-04
Abstract: The present invention relates to a fusion polypeptide which comprises a polypeptide having G-CSF activity and a polypeptide having TPO activity and DNA which codes for the fusion polypeptide, to a fusion polypeptide in which a polypeptide having G-CSF activity and a polypeptide having TPO activity are fused via a spacer peptide and DNA which codes for the fusion polypeptide and to a polypeptide in which the fusion polypeptide comprising a polypeptide having G-CSF activity and a polypeptide having TPO activity is chemically modified with a polyalkylene glycol derivative. It also relates to an anemia-treating composition containing the fusion polypeptide as an active ingredient.
Patent DE-69708285-D1 (DE)
Inventor: LIVAK J
IPC: C12Q1/68
Filed: 1997-06-03
Granted: 2001-12-20
Abstract: The invention relates to passive internal references for use in quantitating the formation of amplification products in a nucleic amplification reaction. The internal amplification reference molecules of the invention comprise a first and second fluorophore joined together through a backbone connector. The first and second fluorophores are joined on the backbone in a configuration that permits the energy transfer from the first fluorophore to the second fluorophore. The backbone connector is selected so as not to bind to the target nucleic acid sequence under nucleic acid amplification conditions. Preferably, the backbone connector is a polynucleotide. Another aspect of the invention is to provide passive internal reference molecule containing reagent compositions for use in nucleic acid amplification reactions. The compositions comprise the internal amplification reference molecule of the invention and a nucleic acid amplification reaction buffer. The reagent compositions, optionally, include additional components required for nucleic acid amplification reactions. The invention also provides improved methods of measuring the amount of amplification product in nucleic acid amplification reactions employing fluorescer-quencher probe assays, including methods for the real-time measurement of amplification product formation. The methods comprise the step of adding the internal reference molecule of the invention to the amplification reaction mixture. Fluorescence of the second fluorophore on the internal reference may then be measured and used to calculate changes in fluorescence of the fluorophore on a fluorescer-quencher probe.
Patent DE-69710607-D1 (DE)
Inventor: ALBERTINI CARLO
IPC: G01N3/30
Filed: 1997-09-26
Granted: 2002-03-28
Abstract: Seismic wave simulation apparatus (1) includes an elastic energy accumulator (4) shaped to induce a simulated seismic wave of known form in a geological specimen (2) in which is embedded the foundation (3) of a building. A hydraulic actuator (5) is used to preload the accumulator (4) in a direction reverse to arrow A and an explosive bolt (6) is exploded, thereby releasing the energy of the accumulator (4) as a seismic wave through the geological specimen (2). The specimen (2) is provided with transducer bars (8) and an electrified metallic thin sheet (9) connected to a Wheastone bridge in order to obtain various measurements. <IMAGE>
Patent DE-69716027-D1 (DE)
Inventor: LEINONEN ANTTI
IPC: D21F9/00
Filed: 1997-08-22
Granted: 2002-11-07
Abstract: PCT No. PCT/FI97/00487 Sec. 371 Date May 4, 1998 Sec. 102(e) Date May 4, 1998 PCT Filed Aug. 22, 1997 PCT Pub. No. WO98/10138 PCT Pub. Date Mar. 12, 1998The invention relates to a method for preventing rewetting of a web in a former. Water is removed from the web (W) by means of dewatering members. The web (W) is formed by forming members and forming rolls on support of a wire loop/loops. The wire loop/loops (10) is/are guided by alignment, guide and/or suction rolls (11, 12). The web (W) supported by a wire (10) is passed by at least two vacuum boxes/chambers (16, 17) after the last suction roll (11). At least two vacuum boxes/chambers (16, 17) are fitted after the last suction roll (11). The web (W) and the wire (10) are arranged to be dewatered by means of a first vacuum box/chamber (16). The transport of moisture from the wire (10) back into the web (W) is prevented by means of a second vacuum box/chamber (17), and a vacuum (P1) in the first vacuum box/chamber (16) is higher than a vacuum (P2) in the second vacuum box/chamber (17).
Patent DE-69717782-D1 (DE)
Inventor: NANDRA NAVRAJ
IPC: G06K7/00
Filed: 1997-02-05
Granted: 2003-01-23
Abstract: The oscillator system forms part of a base station (13), which has regulation (21,22) and command (24) mechanisms, and decoding circuits (25,26,27). The oscillator mechanism is voltage commanded and phase adjusted so that the command frequency signal determined by the base station is adapted to the antenna system.
Patent DE-69721250-D1 (DE)
Inventor: TOURNIER HERVE
IPC: C08F20/52
Filed: 1997-12-23
Granted: 2003-05-28
Abstract: The invention provides, as contrast signal generators in MR imaging of the digestive tract, paramagnetic metal chelates of novel acrylic compounds of formula C(R1R2)=CR3-CO-Z-Z (1) and/or C(R1R2)=CR3-CO-Z-Z-Z-CO-CR3=C(R1R2) (2) in monomer, oligomer, homopolymer and copolymer forms, in which the R1, R2 and R3 represent H or saturated or unsaturated C1-10 aliphatic radicals optionally substituted by one or more OH groups; Z is a covalent bond or a linker spacer and A is a moiety capable of fixing a paramagnetic metal by chelation. Compounds of type (1) useful in the present invention are, for instance the polyalkylene-aminopolycarboxylic acids such as NTA, EDTA, DTPA, DOTA and like structures, possibly involving additional substituents; an example is the compound BOPTA which is a DTPA derivative carrying a benzyloxypropyl group.
Patent DE-69725807-D1 (DE)
Inventor: OHBA AKIO
IPC: G06T1/60
Filed: 1997-02-25
Granted: 2003-12-04
Abstract: A main CPU 11, a main memory 12, a main DMAC (direct memory access controller) 13 and a picture processing unit (graphic processing unit or GPU) 15 are interconnected over a main bus 1. In an input/output unit of each of the main CPU 11 and the GPU 15 are mounted programmable packet engines (PPE) 112, 152 capable of modifying the data packetizing/unpacketizing sequence in order to perform packet transfer with freedom in the packet form. This affords freedom to the packet form to realize efficient development and packing of packet data and efficient drawing processing. <IMAGE>
Patent DE-69727670-D1 (DE)
Inventor: JANG DAVID
IPC: A61F2/82
Filed: 1997-04-25
Granted: 2004-03-25
Abstract: The stent in a non-expanded state has a first column expansion strut pair. A number of the first column expansion strut pair form a first expansion column. A number of second column expansion strut pair form a second expansion column. A number of first serial connecting struts form a first connecting strut column that couples the first expansion column to the second expansion column. The first expansion column, the second expansion column, and the first connecting strut column form a number of geometric cells. At least a portion the number are asymmetrical geometric cells.
Patent DE-69728377-D1 (DE)
Inventor: POWERS B
IPC: C12N1/21
Filed: 1997-01-09
Granted: 2004-05-06
Abstract: Mutants of 2,5-diketo-D-gluconic acid reductase A an enzyme used to produce 2-keto-L-gluconic acid, a precursor of ascorbic acid (vitamin C), are prepared by site-directed mutagenesis. These mutants may exhibit one or more of the following characteristics: improved temperature stability, increased resistance to substrate inhibition, increased turnover of the substrate by the enzyme and increased affinity for the substrate.
Patent DE-69736904-D1 (DE)
Inventor: MANNERS MICHAEL
IPC: C07K7/08
Filed: 1997-12-22
Granted: 2006-12-14
Abstract: A new family of antimicrobial proteins is described. Prototype proteins can be isolated from Macadamia integrifolia as well as other plant species. DNA encoding the protein is also described as well as DNA constructs which can be used to express the antimicrobial protein or to introduce the antimicrobial protein into a plant. Compositions comprising the antimicrobial protein or the antimicrobial protein per se can be administered to plants or mammalian animals to combat microbial infestation.
Patent DE-69737293-D1 (DE)
Inventor: BLUMENFELD MARTA
IPC: C12Q1/6883
Filed: 1997-12-05
Granted: 2007-03-15
Abstract: The present invention concerns, in particular, human flavin-containing monooxygenase 2 (hFMO2), and another human enzyme of the FMO, hFMOx family, their nucleotide and polypeptide sequences. The present invention also concerns vectors for cloning and/or expression containing said nucleotide sequences and cells transformed by these vectors and method for preparing said polypeptides. The invention further concerns methods for selecting compounds and of diagnosing predisposition to pathologies and/or deficiencies related to FMO's and pharmaceutical compositions containing said compounds for treating and/or preventing these pathologies.
Patent DE-69739909-D1 (DE)
Inventor: KOPRESKI MICHAEL S
IPC: C12Q1/6886
Filed: 1997-03-14
Granted: 2010-07-29
Abstract: This invention relates to the use of tumor-derived or associated extracellular ribonucleic acid (RNA) found circulating in blood plasma or serum fraction for the detection, monitoring, or evaluation of cancer or premalignant conditions. Specifically, this invention enables the extraction of circulating RNA from plasma or serum and utilizes nucleic acid amplification assays for the identification, detection, inference, monitoring, or evaluation of any neoplasm, benign, premalignant, or malignant, in humans or other animals, which might be associated with that RNA. Further, this invention allows the qualitative or quantitative detection of tumor-derived or associated extracellular RNA circulating in the plasma or serum of humans or animals with or without any prior knowledge of the presence of cancer or premalignant tissue.
Patent DE-69740064-D1 (DE)
Inventor: AVNERY TZVI
IPC: G21K5/04
Filed: 1997-12-30
Granted: 2011-01-05
Abstract: The invention relates to a method of reconditioning a used electron beam accelerator for reuse, comprising receiving an electron beam accelerator that has been disconnected from an electron beam machine housing at another location; opening the electron beam accelerator vacuum chamber; replacing an electron generator; sealing the electron beam accelerator vacuum chamber; evacuating the vacuum chamber through a sealable outlet; sealing the sealable outlet; preconditioning the electron beam accelerator for high voltage operation in an electron beam machine; and storing the electron beam accelerator for later use.
Patent DE-69804463-D1 (DE)
Inventor: KOLBE V
IPC: A61K47/48
Filed: 1998-07-20
Granted: 2002-05-02
Abstract: The invention concerns novel cationic polymers of formula (I) in which n is a whole number between 0 and 5 and p is a whole number between 2 and 20,000, more particularly p ranges between 10 and 18,000, and advantageously between 200 and 1,000, characterized in that: at least 10%, advantageously 30 to 80%, preferably 70%, of the free NH2 functions are substituted by identical or different hydrophilic R groups; said cationic polymer can further comprise at least a targeting element associated covalently or not with the free NH2 functions and/or said hydrophilic R groups provided that said cationic: polymer contains at least 20%, preferably at least 30%, of free NH2 functions. The invention also concerns a complex comprising at least said cationic polymer associated with at least a therapeutically active substance, in particular a nucleic acid comprising at least a negative charge. The invention is useful for transferring a nucleic acid into target cells, in particular for gene therapy.
Patent DE-69809187-D1 (DE)
Inventor: DACK KEVIN NEIL
IPC: A61P19/00
Filed: 1998-12-16
Granted: 2002-12-12
Abstract: Compounds of formula (I): <CHEM> where the substituents are as defined herein, and salts thereof, are matrix metalloprotease inhibitors.
Patent DE-69812679-D1 (DE)
Inventor: KOZAK ALEXANDER
IPC: A61P29/00
Filed: 1998-09-27
Granted: 2003-04-30
Abstract: The invention discloses stable diesters of chelating agents of divalent metal ions, processes for their preparation and pharmaceutical compositions thereof. Most preferred compounds according to the present invention are stable lipophilic diesters comprising a covalent conjugate of a BAPTA and a pharmaceutically acceptable alcohol. The diesters are useful in a method for treating a condition or disease related to an excess of divalent metal ions, and in particular for the treatment of a condition or disease related to elevated levels of intracellular calcium ions, such as in brain or cardiac ischemia, stroke, epilepsy, Alzheimer's disease or cardiac arrhythmia and in open heart surgery.
Patent DE-69814413-D1 (DE)
Inventor: CHANDLER MICHAEL JOHN
IPC: E04H4/00
Filed: 1998-02-06
Granted: 2003-06-12
Abstract: Apparatus for use with automatic pool cleaners includes a tube which defines a flow channel for water drawn pump from the pool through a house by a remote pump. The tube includes tubular sections (10A, 10B) joined by a joint (11) which operates to move one tube section between first and second angularly displaced positions. Means are provided for periodically causing the movable tube section to move about the joint with sufficient force to impart movement to the hose to cause a change in direction of the cleaner.
Patent DE-69817747-D1 (DE)
Inventor: BARDEAU JOEL
IPC: A61B17/00
Filed: 1998-07-08
Granted: 2003-10-09
Abstract: The invention concerns a stripping device or stripper comprising a semirigid rod (1) extended by a yarn (3) substantially twice as long as the rod (1), in the middle of which is mounted a ring (4).
Patent DE-69819875-D1 (DE)
Inventor: SCHMIDT BRUCE
IPC: A61K31/475
Filed: 1998-03-04
Granted: 2003-12-24
Abstract: The present invention is particularly directed to the use of a derivative of vinblastine, 3',4'-anhydrovinblastine (AHVB), which differs from vinblastine in that it possesses a double bond at the 3',4' position of the caranthine nucleus rather than the hydroxyl group that is present in the parent structure, as an anti-neoplastic agent in the therapeutic treatment of cancer.
Patent DE-69903729-D1 (DE)
Inventor: PROCIDA INGER-MARGRETE
IPC: F16L9/00
Filed: 1999-06-21
Granted: 2002-12-05
Abstract: The invention relates to a flexible, unbonded continuous high-pressure pipe comprised of several layers comprising at least one inner barrier layer, at least one tubular, liquid-permeable reinforcement layer surrounding the barrier layer, and a tubular outer sheath surrounding the tubular reinforcement layer(s), wherein at least one liquid-impervious barrier layer is provided by continuous extrusion of a single-phase aliphatic polyketone polymer, and a method for the production thereof.
Patent DE-69912599-D1 (DE)
Inventor: BENNETT MARGARET
IPC: C08F4/44
Filed: 1999-05-26
Granted: 2003-12-11
Abstract: Ethylene and/or propylene, and alpha-olefins may be copolymerized by contacting then with certain iron or cobalt complexes of selected 2,6-pyridinecarboxaldehydebis(imines) and 2,6-diacylpyridinebis(imines). The polymers produced, some of which are novel, are useful as molding resins.
Patent DE-69915945-D1 (DE)
Inventor: FERRUCCIO LAURENCE
IPC: C07D231/38
Filed: 1999-07-27
Granted: 2004-05-06
Abstract: Preparation of carboxamide oxime derivatives (I) comprises chlorinating an amine derivative (II) to give a chloroimine derivative (III), reacting (III) with an aminopyrazole derivative (IV) to give an amidine derivative (V) and reacting (V) with hydroxylamine to give (I). Preparation of carboxamide oxime derivatives of formula (I) comprises: (a) chlorinating an amine derivative of formula (II) in the presence of an inert solvent, to give a chloroimine derivative of formula (III); (b) reacting (III) with an aminopyrazole derivative of formula (IV), in the presence of an inert solvent, to give an amidine derivative of formula (V); and (c) reacting (V) with a hydroxylamine of one of its salts, in the presence of an inert solvent to give (I). R1 = ary or heteroaryl (optionally substituted); R2 = H, halo, or aryloxy (optionally substituted); R3 = H, halo, OH, CN, NO2, carboxyl, substituted amino, alkyl (optionally substituted), cycloalkyl, aralkyl, aryl, heteroaryl, alkoxy, aryloxy, acyl, acylamino, sulfonylamino, sulfonyl, alkylthio, arylthio, carbamoyl, sulfamoyl or ureido; and R4 = 1-8C alkyl. Steps (a) and (b) are claimed per se. An Independent claim is also included for (V).
Patent DE-69918253-D1 (DE)
Inventor: CIANI LORENZO
IPC: G01B11/14
Filed: 1999-12-20
Granted: 2004-07-29
Abstract: Device and method to measure the gap between substantially static elements with a variable reciprocal position, used to adjust the reciprocal position of said elements (11, 28a, 28b) to obtain a desired transit gap (32), comprising visual recording means (13) connected to a processor (14) equipped with at least display means (14a), said processor (14) being suitable to receive the images filmed by said visual recording means (13) and to automatically compare said images with at least a pre-selected sample mask substantially reproducing the desired gap to be obtained, said processor (14) being suitable to display, in numerical form on appropriate interface windows (24-27), the dimensional discrepancies between the image relating to the actual transit gap (32) defined by said elements (11, 28a, 28b) as filmed by said means (13), and said pre-selected sample mask. <IMAGE>
Patent DE-69918681-D1 (DE)
Inventor: KAMEYAMA YUTAKA
IPC: B01J31/14
Filed: 1999-10-06
Granted: 2004-08-19
Abstract: A process for preparing a  beta -hydroxyester comprising reducing a beta -keto ester in the presence of a salt of ammonium borohydride.
Patent DE-69918869-D1 (DE)
Inventor: VON HOLST HANS
IPC: A42B3/06
Filed: 1999-12-21
Granted: 2004-08-26
Abstract: A protective helmet (1) has an outer shell (2) and an inner shell (3), the outer shell being displaceable relative to the inner shell by means of at last one sliding layer (4) arranged between the the outer shell and the inner shell. In the edge region of the helmet, the outer shell and the inner shell are interconnected by means of members (5), for absorbing energy on displacement of the outer shell on the inner shell. In this way, impact energy from an oblique impact against the helmet can be absorbed during displacement between the outer shell and the inner shell.
Patent DE-69931439-D1 (DE)
Inventor: NOLAN EDWARD
IPC: E04H17/16
Filed: 1999-09-02
Granted: 2006-06-29
Abstract: A prefabricated modular wall element (20) comprises a precast reinforced concrete wall panel (21) having a front face (24). A plurality of spaced-apart individual slabs (33) of stone or brick are partially embedded in the front face (24) of the panel (21) during casting of the panel (21) and project outwardly of the front face (24) with channels being formed between the slabs (33). The slabs (33) are arranged on the front face (24) such that the front face (24) simulates a wall constructed of stone. A pair of spaced-apart support legs (38) are provided at a bottom (27) of the wall panel (21) for keying into a concrete foundation (42) to support the wall element (1) in an upright position. <IMAGE>
Patent DE-69931887-D1 (DE)
Inventor: ALLEN ROBERT JOHN
IPC: A61G3/06
Filed: 1999-10-05
Granted: 2006-07-27
Abstract: An extendable ramp assembly includes a chassis, a first ramp slidably movable relative to the chassis and hingably connected to the chassis, and a second ramp carried by the first ramp and movable relative to the chassis and the first ramp. Separate structure is provided for extending and retracting both the first and second ramps. A first mechanism is provided for detecting whether either or both of the first and second ramps abuts an obstruction when at least one of the ramps is being extended. A second mechanism is provided for stopping the extension of at least one of the ramps or for retracting at least one of the ramps in the event of the detecting mechanism detecting the obstruction.
Patent DE-69938130-D1 (DE)
Inventor: GORODETSKY RAPHAEL
IPC: C12N5/079
Filed: 1999-05-26
Granted: 2008-03-27
Abstract: A group of novel peptides having a sequence selected from the group consisting of KGSWYSMRKMSMKIRPFFPQQ, LTIGEGQQHHLGGAKQAGDV and RGADYSLRAVRMKIRPLVTQ are provided. Compositions and methods of use of these peptides are also provided.
Patent DE-69939695-D1 (DE)
Inventor: DUCHOVNE YORAM
IPC: B41J2/205
Filed: 1999-04-20
Granted: 2008-11-20
Abstract: A method of operating printing heads (H) (Fig. 8), particularly of the ink-jet type. The method includes the steps of providing a series of more than one printing heads (H), mounting of the heads (H) on a common carriage in a side-by-side, partly sidewise overlapping position. The method also includes activating the heads (H) for printing on a substrate in a programmed periodical sequence.
Patent DE-502004001885-D1 (DE)
Inventor: MEISSNER ALEXANDER DR
IPC: B25J9/18
Filed: 2004-09-13
Abstract: At least two controllers (8-10) with differing axes are coupled to each other with axial overlap. The coupling behavior is configurable and the coupling loop includes a low pass filter (15, 16), absolute value block (13), inverter, amplifier and a saturation section. The corresponding robot and painting plant are also claimed.