baber/WOPTO huggingface dataset:
Patent WO-2020188126-A8 (WO)
Inventor: CONTELL ALBERT EUGENIO
IPC: A47J19/02
Filed: 2019-03-18
Abstract: A fruit squeezing system, with a feed system (1) and cutting and squeezing means with a pair of cup assemblies (3) that are vertically displaceable by vertical displacement means (10) and rotationally, in opposite directions, by rotation means (11); below these a cutting assembly (4) with a blade (5) and peel extraction means; and one pair of fixed squeezer balls (6), each of these below one of the cup assemblies, for the vertical squeezing of the fruit halves by means of the vertical displacement of the cup assemblies (3). The system has a first motor (12) exclusively for the operation of the vertical displacement means (10); means for the measurement of the intensity thereof, and a control unit which independently governs the first motor (12) and halts it when the intensity measured exceeds a pre-set range of values.
Patent WO-2015110726-A8 (WO)
Title: Moteur a combustion externe
Inventor: DE LARMINAT ALAIN
IPC: F02G1/043
Filed: 2015-01-07
Abstract: L'invention concerne un moteur à combustion externe comprenant au moins : - un cylindre (3) présentant une extrémité (3c) fermée - un piston (2) mobile dans le cylindre délimitant une chambre (6a, 6b, 6c) remplie par un fluide gazeux, au moins un réchauffeur (4) et au moins un refroidisseur (5a ou 5b) agissant sur la chambre dans le cylindre (3) pour déplacer le piston (2) mobile entre une première position d'expansion maximum de la chambre et une deuxième position de compression maximum de la chambre, un mécanisme d'asservissement du mouvement en translation du piston (2), caractérisé en ce que le piston (2) est constitué d'au moins une base (10) coulissant dans le cylindre (3) de façon étanche, d'un déplaceur (11) coulissant de façon non étanche dans le cylindre (3) et d'un arbre (12) d'entraînement du déplaceur (11) par la base (10).
Patent WO-2013144673-A8 (WO)
Title: Détermination chirale utilisant des signatures spectrales en demi-fréquence
Inventor: DASGUPTA ANJAN KR
IPC: G01N21/64
Filed: 2012-08-06
Abstract: L'invention concerne une technique permettant de déterminer si oui ou non un matériau fluorescent présente une propriété dépendante directionnellement, comme une anisotropie ou une chiralité, lequel consiste à illuminer la particule à sa longueur d'onde d'excitation afin de stimuler une émission fluorescente à une longueur d'onde de pleine fréquence (fondamentale) et une longueur d'onde de demi-fréquence. Le rapport entre la puissance du signal de pleine fréquence et la puissance du signal de demi-fréquence donne une indication de la propriété directionnellement dépendante de l'échantillon. Cette analyse spectrale en demi-fréquence peut être utilisée pour trier des particules anisotropiques suspendues dans un liquide s'écoulant dans un cytomètre à flux. Par exemple, cette technique peut être utilisée afin de séparer des composés racémiques d'énantiomères chiraux de cellules, de composés pharmaceutiques ou d'autres échantillons.
Patent WO-2016098910-A8 (WO)
Inventor: MATSUFUJI SHINICHI
IPC: A61Q1/00
Filed: 2015-12-17
Abstract: The present invention relates to a composite particle comprising: at least one hydrophilic core particle; and a plurality of hydrophobic particles, wherein the surface of the hydrophilic core particle is substantially discontinuously covered by the hydrophobic particles. The novel composite particle according to the present invention can have surface active properties sufficient to prepare stable Pickering emulsions, and can maintain the surface active properties over a long period of time. The present invention also relates to a method for preparing the above composite particle.
Patent WO-2018186742-A8 (WO)
Title: Method of and atomic force microscopy system for performing subsurface imaging
Inventor: PIRAS DANIELE
IPC: G01N29/06
Filed: 2018-04-04
Abstract: The document relates to a method of performing subsurface imaging of embedded structures underneath a substrate surface, using an atomic force microscopy system. The system comprises a probe with a probe tip, and a sensor for sensing a position of the probe tip. The method comprises the steps of: positioning the probe tip relative to the substrate: applying a first acoustic input signal to the substrate; applying a second acoustic input signal to the substrate; detecting an output signal from the substrate in response to the first and second acoustic input signal; and analyzing the output signal. The first acoustic input signal comprises a first signal component and a second signal component, the first signal component comprising a frequency below 250 megahertz and the second signal component either including a frequency below 2.5 megahertz or a frequency such as to provide a difference frequency of at most 2.5 megahertz with the first signal component, such as to enable analysis of an induced stress field in the substrate; and wherein the second acoustic input signal comprises a third signal component having a frequency above 1 gigahertz, such that the return signal includes a scattered fraction of the second acoustic input signal scattered from the embedded structures. This enables to perform imaging a various depths in one pass, across a large range of depths.
Patent WO-2018203751-A8 (WO)
Title: Therapeutic effects of guanabenz treatment in vanishing white matter
Inventor: VAN DER KNAAP MARGO SIENTJE
IPC: A61K31/00
Filed: 2018-05-04
Abstract: The invention relates to Guanabenz or an analogue thereof for use in the treatment and to methods of treatment of a subject that has vanishing white matter (VWM), comprising administering the compound Guanabenz or an analogue thereof to the subject in need thereof. Also provided are methods with which the success of a medical intervention in a subject with VWM can be determined. Such methods comprise quantifying the translocation of Bergmann glia into the molecular layer in the cerebellum in a suitable sample of the sub ject. The sample is typically a post mortem sample.
Patent WO-2004076489-A8 (WO)
Title: Anticorps modifie
Inventor: BOGEN BJARNE
IPC: C07K16/28
Filed: 2004-02-25
Abstract: La présente invention concerne un nouveau type de molécules humaines recombinées de type anticorps utiles dans le traitement par exemple du myélome multiple. Ces molécules, appelées vaccicorps, fixent l'APC et elles sont capables de déclencher des réponses immunes à la fois des lymphocytes T et des lymphocytes B. De plus, les vaccicorps se fixent de façon divalente à l'APC pour favoriser un début de réponse immune plus efficace. Par conséquent, un objectif principal de la présente invention est d'induire une réponse immune forte afin de rendre les adjuvants redondants. Les vaccicorps comprennent un dimère d'une unité monomère comprenant une unité de ciblage ayant une spécificité pour une molécule de surface sur APC, reliée par une région charnière et un domaine Cη3 à une unité antigénique dans l'extrémité COOH-terminale; cette dernière étant par exemple d'origine lymphome ou myélome B (figure 1), bien que toute origine soit possible du fait du système de clonage par cassette dans le vecteur d'expression. Ladite molécule est capable d'induire une réponse immune contre le myélome multiple, par extension une stratégie de vaccination globale pour n'importe quel polypeptide devrait être faisable. La présente invention concerne également une séquence d'ADN codant pour cette molécule recombinée basée sur des anticorps, des vecteurs d'expression contenant ces séquences d'ADN, des lignées cellulaires comprenant lesdits vecteurs d'expression, le traitement de mammifères de façon préférentielle par immunisation au moyen d'ADN de vaccicorps, d'ARN de vaccicorps ou d'une protéine de vaccicorps, et enfin des agents pharmaceutiques et un kit contenant lesdites molécules.
Patent WO-2004072687-A8 (WO)
Title: Procede et appareil pour corriger la vue au moyen d'un refracteur electroactif
Inventor: BLUM RONALD D
IPC: A61P17/06
Filed: 2004-02-05
Abstract: L'invention concerne un réfracteur électroactif, ainsi qu'une méthode d'utilisation de ce réfracteur pour mesurer la correction optique requise pour un patient. Ce réfracteur électroactif comprend une série de lentilles électroactives adressables individuellement. Ces lentilles possèdent une puissance optique positive ou négative lorsqu'un potentiel électrique est appliqué à travers la lentille et une puissance optique neutre en l'absence d'application de potentiel électrique à travers la lentille. Chaque lentille fournit une puissance optique qui constitue une partie d'une puissance optique nette de la série de lentilles lorsqu'un patient regarde à travers le réfracteur. La puissance optique du réfracteur peut être réglée de façon incrémentielle par modification de la distribution du potentiel électrique à travers les différentes lentilles de la série de façon à fournir une puissance optique croissante ou décroissante jusqu'à ce que le patient atteigne un niveau voulu de netteté et qu'une correction optique soit déterminée.
Patent WO-2007073509-A8 (WO)
Title: Modified annexin proteins and methods for their use in organ transplantation
Inventor: ALLISON ANTHONY
IPC: A61K38/00
Filed: 2006-10-25
Abstract: Modified annexin proteins, including a homodimer of human annexin V, are provided. Methods for their use, such as to prevent thrombosis without increasing hemorrage and to attenuate ischemia-reperfusion injury (IPI), are also provided. The modified annexins bind phosphatidylserine (PS) on cell surfaces, thereby preventing the assembly of the prothromkinase complex. The modified annexin decreases the binding of leukocytes and platelets during post-ischemic reperfusion, thereby restoring microvascular blood flow and decreasing organ damage.
Patent WO-2010101986-A8 (WO)
Title: Capteur de pression électriquement isolé, compatible avec des milieux, pour des applications à haute température
Inventor: SUMINTO JAMES TJANMENG
IPC: G01L9/06
Filed: 2010-03-03
Abstract: La présente invention concerne un capteur de pression muni d'éléments de détection isolés électriquement et physiquement d'un milieu sous pression. Un capteur de pression absolue possède une cavité de référence qui peut être sous vide ou à pression nulle, contenant les éléments de détection. La cavité de référence est formée par la liaison d'une tranche de coiffe en creux avec une tranche de référence comportant un diaphragme micro-usiné. Des éléments de détection sont disposés sur un premier côté du diaphragme. Le milieu sous pression a accès à un second côté du diaphragme opposé au premier côté où les éléments de détection sont disposés. Une tranche d'espacement peut être utilisée pour servir de support structurel et soulager la contrainte exercée sur la tranche de référence. Dans un mode de réalisation, des trous d'interconnexion conducteurs verticaux sur toute la tranche sont utilisés pour amener les connexions électriques depuis les éléments de détection vers l'extérieur de la cavité de référence. Dans un autre mode de réalisation, des pastilles de liaison périphériques sur la tranche de référence sont utilisées pour amener les connexions électriques depuis les éléments de détection vers l'extérieur de la cavité de référence.
Patent WO-2014055369-A8 (WO)
Title: Système et procédé de mélangeur cellulaire
Inventor: WADDS NATHAN
IPC: A63F1/12
Filed: 2013-09-27
Abstract: L'invention concerne un dispositif de manipulation de cartes automatique (110), comprenant un dispositif de manipulation de cartes (130) pourvu d'un contrôleur, ce dispositif étant configuré pour mélanger un ensemble d'entrée de cartes et distribuer un ensemble de sortie de cartes résultant du mélange; ainsi qu'un module de communication (146) couplé fonctionnel au contrôleur, le module de communication étant configuré pour envoyer et recevoir des informations relatives au fonctionnement du dispositif de manipulation de cartes par un port de communication (148) configuré pour un couplage fonctionnel à un réseau cellulaire (136), les informations relatives au fonctionnement du dispositif de manipulation de cartes comprenant des informations relatives à l'utilisation de ce dispositif; un facteur relatif aux frais d'utilisation pour le dispositif de manipulation de cartes étant l'utilisation de ce dispositif.
Patent WO-2015112773-A8 (WO)
Title: Very high speed, high density electrical interconnection system with edge to broadside transition
Inventor: CARTIER MARC B
IPC: H01R12/71
Filed: 2015-01-22
Abstract: A modular electrical connector with broadside coupled signal conductors in a right angle intermediate portion and edge coupled end portions. Broadside coupling provides balanced pairs for very high frequency operation, while edge coupling provides a high density interconnection system at low cost. Each module has separately shielded signal conductor pairs. The shielding is shaped to avoid or suppress undesirable propagation modes within an enclosure formed by shielding per module. Lossy material may be selectively placed within and outside the shielding per module to likewise avoid or suppress unwanted signal propagation.
Patent WO-2016112251-A8 (WO)
Inventor: ALBRECHT BRIAN K
IPC: A61K31/496
Filed: 2016-01-08
Abstract: The present invention relates to compounds of formula (I), wherein: X is C(=O) or S(O) 2 ; R 1  is selected from the group consisting of N-linked piperazinyl, relinked piperidine, and N-linked diazabicyclo[3.2.1]octane, wherein R 1  is optionally substituted with one or more groups; R 2  and R 3  are each independently selected from H, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, and C 3-8 cycloalkyl, wherein any C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, and C 3-8 cycloalkyl is optionally substituted with one or more groups; or R 2  and R 3  taken together with the carbon to which they are attached form a 3-, 4-, 5-, or 6-membered carbocyclic ring that is optionally substituted with one or more groups; R 4  and R 5  are each independently selected from H, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, and C 3-8 cycloalkyl, wherein any C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, and C 3-8 cycloalkyl is optionally substituted with one or more groups; or R 4  and R 5  taken together with the carbon to which they are attached form a 3-, 4-, 5-, or 6-membered carbocyclic ring that is optionally substituted with one or more groups; and R 6  is a 5-10 membered heteroaryl, 5-10 membered heterocycle, or a 6-10 membered aryl, which 5-10 membered heteroaryl, 5-10 membered heterocycle, and 6-10 membered aryl is optionally substituted with one or more groups; useful as inhibitors of one or more histone demethylases, such as KDM2b. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Patent WO-2017027529-A8 (WO)
Inventor: BEAR MARK FIRMAN
IPC: A61P27/10
Filed: 2016-08-09
Abstract: Amblyopia is a prevalent form of visual impairment that generally arises during infancy and early childhood when inputs to the visual cortex form the two eyes are poorly balanced. Disclosed herein are methods involving retinal inactivation of at least one retina to treat visual impairment in the form of amblyopia or other conditions.
Patent WO-2018140615-A8 (WO)
Inventor: KEPECS ADAM
IPC: H01P11/00
Filed: 2018-01-25
Abstract: Provided are devices that have a distal portion configured to be implanted in a brain of a subject. The distal portion includes one or more emitters configured to emit light in the visible spectrum. The device includes a proximal portion configured to be external to the brain of the subject while the distal portion is implanted, wherein the proximal portion includes at least one waveguide in optical communication with the one or more emitters. The at least one waveguide defines a cross-sectional width less than 500 nm. The at least one waveguide is optionally coupled to a heating element that is optionally configured to adjust a phase of light within the at least one waveguide.
Patent WO-2018175027-A8 (WO)
Title: Three-way switchable clutch
Inventor: INCE MARION
IPC: F16D41/08
Filed: 2018-02-20
Abstract: A three-way switchable clutch, including: outer and inner rings; and pawls non-rotatably connected to the outer ring. For a free-wheel mode, the inner and outer rings are rotatable with respect to each other. For first and second clutch modes, the pawls are displaceable to engage the inner ring to non-rotatably connect the inner and outer rings. For the first mode: rotation of one of the inner or outer rings is in a first circumferential directions and the one of the inner or outer rings is rotatable with respect to the other of the inner or outer ring in a second circumferential direction. For the second mode: rotation of the one of the inner or outer rings is in the second circumferential direction and the one of the inner or outer rings is rotatable with respect to the other of the inner or outer rings in the first circumferential direction.
Patent BR-102018069258-A8 (BR)
Title: sistema de tour virtual com possibilidade de compras online
Inventor: EDUARDO GENS MORAIS
IPC: G06T19/00
Filed: 2018-09-21
Abstract: a presente patente de invenção compreende-se a uma ferramenta de compra/venda/aluguel e/ou reserva de interesse de produtos e/ou serviços e/ou bens e/ou conjuntos, em um sistema de e-commerce (comércio pela internet) integrado ao tour virtual interativo em lojas/espaços virtuais, semelhante ao espaço real, que foi escaneado/fotografado utilizando câmeras 360/panorâmicas/3d ou similares. com o objetivo de possibilitar e/ou promover a comercialização de produtos e/ou serviços demandados por um tipo de cliente consumidor, em uma página da internet. a navegação pelo sistema de tour virtual interativo é feita através de dispositivos móveis (celulares, tablets) e/ou computadores, utilizando a navegação com o mouse, teclado e/ou interfaces touch.
Patent BR-112013024028-A8 (BR)
Title: Composição fluida destinada a ser aplicada sobre a pele
Inventor: NATHALIE DERAIN
IPC: A61Q17/00
Filed: 2012-03-23
Abstract: COMPOSIÇÃO FLUIDA DESTINADA A SER APLICADA SOBRE A PELE. A presente invenção se refere a uma composição em forma fluida destinada a formar um curativo sobre a pele. Essa composição contém de 6 a 12% em peso do peso total da composição de um derivado de celulose, de 5 a 15% em peso do peso total da composição de um óleo vegetal, e um solvente volátil. A razão de massas óleo/celulose está compreendida entre 0,8 e 1,5. Essa nova base de curativo permite a obtenção de urn filme sobre a pele dotado de resistências satisfatórias à água e a fricções. O filme é flexível e suficientemente confortável, particularmente quando o curativo é aplicado sobre uma região consideravelmente extensa da pele.
Patent BR-112014022096-A8 (BR)
Title: Propagação de retorno de usuário em postagens compartilhadas
Inventor: LANTIAN ZHENG
IPC: G06Q50/30
Filed: 2013-02-14
Abstract: PROPAGAÇÃO DE RETORNO DE USUÁRIO EM POSTAGENS COMPARTILHADAS. A propagação de retorno de usuário em postagens compartilhadas é descrita, incluindo receber uma indicação de usuário associada com o conteúdo de republicação. O conteúdo de republicação é associado com o conteúdo de postagem. O conteúdo de postagem inclui pelo menos um item fornecido em um website. O conteúdo de republicação inclui pelo menos outro item fornecido em outro website ou o website, e pelo menos outro item é associado com pelo menos um item. O conteúdo de republicação é determinado como sendo associado com o conteúdo de postagem. Os dados de retorno de postagem baseados na indicação de usuário são identificados. Os dados e retorno de postagem são associados com o conteúdo de postagem, e os dados de retorno de postagem representam indicação de usuário anterior. Os dados de retorno de postagem são atualizados com base na indicação de usuário.
Patent BR-112015028917-A8 (BR)
Title: administração de reutilização de medicações retornadas
Inventor: MARIA CONSOLACION JASKELA
IPC: G16H10/60
Filed: 2014-05-22
Abstract: abstract methods for managing a return of a prepared medication are provided. in one aspect, a method includes receiving an identification of at least one returned medication delivered to a first location, and receiving an order for another medication. the method also includes determining whether the at least one returned medication is usable for completing the order of the other medication, and when the determination indicates that the at least one returned medication is usable for completing the order of the other medication, providing a notification indicating that the at least one returned medication is usable for completing the order of the other medication. systems and machine-readable media are also provided tradução do resumo resumo patente de invenção: "administração de re-utilização de medicações retornadas". são proporcionados métodos para administrar um retorno de uma medicação preparada. em um aspecto, um método inclui receber uma identificação de pelo menos uma medicação retornada liberada para um primeiro local, e receber uma ordem para outra medicação. o método também inclui determinar se a pelo menos uma medicação retornada é utilizável para completar a ordem da outra medicação, e quando a determinação indica que a pelo menos uma medicação retornada é utilizável para completar a ordem da outra medicação, prover uma notificação indicando que a pelo menos uma medicação retornada é utilizável para completar a ordem da outra medicação. sistemas e meios legíveis por máquina também são proporcionados 1 26646114v1
Patent BR-112016012662-A8 (BR)
Title: sistema de inspeção automática e método de inspeção automática
Inventor: ALESSIO ANDOLFI
IPC: G01N27/90
Filed: 2014-11-06
Abstract: trata-se de um sistema de inspeção portátil automático que inclui um retentor de parte para reter um componente a ser inspecionado, e um atuador giratório acoplado ao retentor de parte. o sistema inclui, adicionalmente, uma sonda de corrente de foucault para realizar a varredura do componente, e para fornecer sinais de corrente de foucault. o sistema inclui, também, uma unidade de autoalinhamento acoplada à sonda de corrente de foucault e é configurada para alinhar um eixo geométrico da sonda substancialmente perpendicular a uma superfície do componente, e para manter contato constante com a dita superfície do componente. o sistema também inclui um atuador linear acoplado à unidade de autoalinhamento, para fornecer movimento da sonda de corrente de foucault ao longo dos eixos geométricos x, y e z. uma unidade de controle de moção é acoplada ao atuador giratório e ao atuador linear para controlar o atuador giratório e o atuador linear para mover a dita sonda em torno do componente em conformidade com um plano de varredura.
Patent BR-112020025100-A8 (BR)
Title: Dispositivos microfluídicos tridimensionais para a liberação de princípios ativos
Inventor: MARC ALARY
IPC: A61K9/00
Filed: 2019-06-28
Abstract: A invenção se refere a um dispositivo de liberação dérmica que inclui um filme que tem uma primeira e uma segunda superfícies principais voltadas para fora; pelo menos um reservatório para líquidos disposto dentro do filme; ao menos um canal microfluídico que tem uma dimensão transversal entre cerca de 100 nm e 0,5 mm disposto dentro do filme e em comunicação fluida com o pelo menos um reservatório de líquido; e pelo menos uma porta de saída conectada de modo operacional à primeira superfície principal voltada para fora do filme em comunicação fluida com o ao menos um canal microfluídico.
Patent WO-02079504-A9 (WO)
Title: Cellules neotiques et endoapoptotiques et detection de neose et d'endoapoptose
Inventor: RAJARAMAN RENGASWAMI
IPC: G01N33/50
Filed: 2002-03-28
Abstract: L'invention concerne des procédés permettent d'isoler les cellules impliquées dans la néose, des compositions de cellules ou de tissus présentant une population accrue de cellules intervenant dans la néose, ainsi que des procédés permettant d'identifier des composés modulant la néose et des méthodes permettant de diagnostiquer l'évolution des tumeurs.