baber/WOPTO huggingface dataset:
Patent WO-2022186954-A1 (WO)
Title: Method and system of implenting partitioned blockchain
Inventor: TREITLINGER THOMAS
IPC: H04L67/1097
Filed: 2022-02-08
Abstract: A method for representing state of an asset through a partitioned blockchain includes: storing a partitioned blockchain including a plurality of blocks; receiving a first new block including at least one first new transaction data value for each of a plurality of partition groups, where one of the first new transaction data values in a first partition group includes a specific asset identifier; receiving a second new block including at least one second new transaction data value for each of the plurality of partition groups, where one of the second new transaction data values in a second partition group includes the specific asset identifier; detecting the specific asset identifier in the second partition group in the second new block; and performing one or more predetermined actions after detecting the specific asset identifier.
Patent WO-2023003598-A1 (WO)
Inventor: KU JONGWUK
IPC: G02B26/10
Filed: 2022-02-17
Abstract: An optical scanner includes a light source unit, a deflector comprising at least three first coupling portions; an imaging optical system to form an image by scanning deflected light from the deflector on an exposure object; and a frame comprising at least three second coupling portions respectively corresponding to the at least three first coupling portions, wherein an assembly reference line is a shorter line among a first line between two second coupling portions relatively close to a rotational axis of the deflector from among the at least three second coupling portions and a second line perpendicular to a line from another second coupling portion to the first line, and positions of the at least three second coupling portions are such that the assembly reference line faces a direction in which an error of a diameter of beam spots formed on the exposure object is within a reference error.
Patent WO-2022178318-A1 (WO)
Inventor: KERWIN DIANA
IPC: A61K31/70
Filed: 2022-02-18
Abstract: Disclosed herein are methods alleviating or reducing inflammation and/or oxidative stress induced by oxidized LDL, reducing an amount (e.g., concentration) total cholesterol, reducing accumulation of total LDL, reducing an amount (e.g., concentration) of and/or a size (e.g., average size, maximum size) of, and/or changing the shape of circulating (e.g., blood, serum, plasma) cholesterol crystals (and/or clots comprising cholesterol crystals) in an individual. Further disclosed herein are methods of treating familial hypercholesterolemia, reducing statin, cholesterol uptake inhibitor or PCSK9 inhibitor treatment, or reducing a frequency of, or delaying plasmapheresis treatment of a subject diagnosed with or suspected to have familial hypercholesterolemia. The methods generally involve administering a therapeutically effective amount of 2-hydroxypropyl-beta-cyclodextrin to the individual. Further provided herein are pharmaceutical compositions comprising a therapeutically effective amount of 2-hydroxypropyl-beta-cyclodextrin and a pharmaceutically acceptable excipient.
Patent WO-2023172240-A1 (WO)
Title: Compositions pharmaceutiques à libération prolongée pour le traitement d'affections oculaires
Inventor: SAADEH DENNIS E
IPC: A61P27/02
Filed: 2022-03-07
Abstract: La présente invention concerne des procédés et des compositions pour des formulations à libération prolongée pour le traitement d'affections ophtalmiques. Ces formulations comprennent un agent pharmaceutique, un polymère cationique, un polymère non ionique et un support pharmaceutique et sont essentiellement exemptes de conservateur. Les formulations de l'invention sont particulièrement utiles pour une libération prolongée et contrôlée de médicaments et ont de faibles effets secondaires.
Patent WO-2022197880-A1 (WO)
Inventor: YOSHIOKA MASAHIRO
IPC: G05F3/30
Filed: 2022-03-17
Abstract: A bandgap voltage reference circuit includes first and second transistors (Q1 and Q2) (e.g., 3-terminal BJTs or diode-connected BJTs), and a PTAT element (e.g., resistance or capacitance). The first transistor (Q1) is at a first die location, and operates with a first base-emitter voltage. The second transistor (Q2) is at a second die location, and operates with a second base-emitter voltage. Each of the first and second transistors may include multiple individual parallel-connected transistors. The PTAT element is operatively coupled to the first and second transistors such that a voltage difference between the first and second base-emitter voltages drops across the PTAT element. The first and second locations are separated by a distance (e.g., 1.5% or more of die length, or such that the respective centroids of the first and second transistor are spaced from one another). Such spatial distribution helps mitigate voltage shift induced by mechanical stress, and is insensitive to process variation.
Patent WO-2022235376-A1 (WO)
Title: Multi-corner irrigation system having multiple steerable points within mobile irrigation machine and method for implementing the same
Inventor: KASTL JOHN
IPC: A01G25/09
Filed: 2022-04-08
Abstract: The present invention provides a multi-corner irrigation system having multiple steerable points which can quickly and efficiently irrigated tight corners during irrigation operations. According to an exemplary preferred embodiment, the present invention may preferably include a system for use with a self-propelled irrigation system having at least one span and a drive system for moving the span. According to a further preferred embodiment, the system preferably may include: a main section assembly having one or more interconnected spans supported by one or more drive towers; a first articulated span having an inner end and an outer end; a second articulated span having an inner end and an outer end; and an extension span. According to a further preferred embodiment, the first and second articulating spans are supported by a first drive tower which is steerable and a second drive tower which is steerable.
Patent WO-2022240547-A1 (WO)
Title: Improved x-ray imaging in cross-section using un-cut lamella with background material
Inventor: ZUR YEHUDA
IPC: G01N23/2251
Filed: 2022-04-15
Abstract: A method of performing x-ray spectroscopy material analysis of a region of interest within a cross-section of a sample using an evaluation system that includes a focused ion beam (FIB) column, a scanning electron microscope (SEM) column, and an x-ray detector, including: forming a lamella having first and second opposing side surfaces in the sample by milling, with the FIB column, first and second trenches in the sample to expose the first and second sides surface of the lamella, respectively; depositing background material in the second trench, wherein the background material is selected such that the background material does not include any chemical elements that are expected to be within the region of interest of the sample; generating a charged particle beam with the SEM column and scanning the charged particle beam across a region of interest on the first side surface of the lamella such that the charged particle beam collides with the first side surface of the lamella at a non-vertical angle; and detecting x-rays generated while the region of interest is scanned by the charged particle beam.
Patent WO-2022225875-A1 (WO)
Title: Sialydase linked hiv antibodies and methods of use
Inventor: ABDEL-MOHSEN MOHAMED
IPC: A61K39/00
Filed: 2022-04-19
Abstract: Disclosed herein are compositions for targeted desialylation of HIV- infected cells, including neutralizing HIV antibodies conjugated to desialylation enzymes, and methods of use for treating or preventing an HIV infection or a disease or disorder associtate with an HIV infection.
Patent WO-2022232221-A1 (WO)
Title: Vaccins autologues bihapténisés et leurs utilisations
Inventor: BERD DAVID
IPC: A61K39/39
Filed: 2022-04-27
Abstract: Dans certains modes de réalisation, l'invention concerne des méthodes de traitement de cancers du col de l'utérus, y compris de cancers du col de l'utérus qui sont résistants à une thérapie par inhibiteur du point de contrôle immunitaire, et de cancers du col de l'utérus qui ne répondent pas à une thérapie par inhibiteur du point de contrôle immunitaire ou ont acquis une résistance à une thérapie par inhibiteur du point de contrôle immunitaire.
Patent WO-2022240947-A1 (WO)
Title: Utilisation d'inhibiteurs de sos1 avec des inhibiteurs de mtor pour traiter des cancers
Inventor: LEE BIANCA JENNIFER
IPC: C07K14/47
Filed: 2022-05-11
Abstract: La présente divulgation concerne des associations d'inhibiteurs de SOS1 et d'inhibiteurs de MTOR utiles dans le traitement de maladies ou de troubles.
Patent WO-2023283009-A1 (WO)
Inventor: CHEN WEN-YI
IPC: H03K19/003
Filed: 2022-06-06
Abstract: Un circuit de protection contre les décharges électrostatiques comprend un transistor d'attaque avec un drain qui est couplé à un plot d'entrée/sortie (E/S) d'un dispositif à circuit intégré et une source qui est couplée à un premier rail d'une alimentation électrique dans le dispositif à circuit intégré, et une diode qui couple le plot E/S au premier rail et qui est configurée pour être polarisée en sens inverse lorsqu'une tension nominale est appliquée au plot E/S. Le circuit de protection contre les décharges électrostatiques comprend un transistor de traction de grille qui couple une grille du transistor d'attaque au plot E/S ou au premier rail. Le transistor de traction de grille peut être configuré pour présenter un trajet d'impédance élevée entre la grille du transistor d'attaque et le plot E/S ou le premier rail lorsque la tension nominale est appliquée au plot E/S et un trajet d'impédance faible lorsqu'un signal de surtension est appliqué au plot E/S.
Patent WO-2022266227-A1 (WO)
Inventor: EGAN RICHARD L
IPC: G01N33/50
Filed: 2022-06-15
Abstract: L'invention concerne des procédés, des dispositifs et des kits pour l'identification rapide d'individus préalablement infectés par un pathogène bactérien ou viral, tel que le virus du SARS-CoV-2, ou vaccinés contre celui-ci. Des lymphocytes T mémoires spécifiques de pathogènes, tels que des lymphocytes T mémoires spécifiques du SARS-CoV-2, fournissent une indication d'une infection précédente, si détectée. Les lymphocytes T mémoires sont dosés par exposition à des antigènes bactériens et/ou viraux spécifiques, puis testés pour une activation par analyse de la teneur en nucléotides.
Patent WO-2023278681-A1 (WO)
Inventor: POLINSKE BEAU
IPC: H04L1/04
Filed: 2022-06-30
Abstract: An application sends the redundant instances of the data packet via an audio frequency speaker built into that external computing device to the microphone of the hearing assistance device. A microphone receives a wireless communication including a command that contains two or more redundant instances of a data packet, each instance contains a same command. Each redundant data packet is sent on its own carrier frequency in an audio frequency band. A configurable filter engine passes a signal corresponding to the same command transmitted by the audio frequency speaker built into that external computing device through one or more audio band band-pass filters. A control processor examines the band-passed signal and extracts information to extract the content payload of the data packet. A signal processor carries out an operation corresponding to the command from the content payload of the data packet in the hearing assistance device.
Patent WO-2023075878-A1 (WO)
Inventor: HU BING
IPC: G06F11/30
Filed: 2022-07-28
Abstract: L'invention concerne des systèmes, des procédés et des dispositifs permettant une évaluation intelligente de panne et une gestion d'aperçu pour des systèmes de surveillance et de gestion d'incident. Un ensemble de journaux d'incidents associés à un service infonuagique sont reçus par un système de fournisseur de services infonuagiques. Chaque journal d'incidents comporte des données d'impact correspondant à un incident respectif qui s'est produit pendant une période d'évaluation. Les données d'impact comportent un compte d'interruptions représentatif d'un certain nombre d'interruptions sur des ressources provoquées par l'incident respectif. Un temps de ressource actif total représentatif de l'activité des ressources pendant la période d'évaluation est déterminé. Un taux d'interruption est déterminé pour la période d'évaluation par addition de comptes d'interruptions pour générer un compte d'interruptions total et par division du nombre total d'interruptions par le temps de ressource actif total. Un aperçu actionnable applicable au service infonuagique est généré sur la base du taux d'interruption et des journaux d'incidents.
Patent WO-2023034033-A1 (WO)
Inventor: DARLAGE COLBY
IPC: F21S43/40
Filed: 2022-08-18
Abstract: A light system comprising: (a) one or more bezels; (b) an internal lens located within and in communication with the one or more bezels, wherein the internal lens has a height; and (c) a light source that directs light from the light system to a location outside of a vehicle that is configured to house the light system, wherein some of the light is directed to the location outside of the vehicle directly through the internal lens; wherein the one or more bezels include a reflector surface located outside of the height of the internal lens and some of the light from the light source is redirected by the internal lens to the reflector surface of the one or more bezels so that the light is redirected outside of the height of the internal lens to the location outside of the vehicle.
Patent WO-2023039179-A1 (WO)
Title: Machine learning techniques for detecting reduced blood flow conditions
Inventor: VISWESWARAN SHYAM
IPC: A61B5/24
Filed: 2022-09-09
Abstract: This document describes machine learning techniques for detecting reduced blood flow conditions, such as ischemia and stroke, in real-time based on electroencephalography (EEG) signals. In one aspect, a method includes receiving patient data that includes a set of EEG signals generated by an EEG device measuring brain function of the patient. A set of feature values are generated for the patient using the EEG signals. The feature values are provided as input to a trained machine learning model that has been trained to detect reduced blood flow conditions of patients. An indication of whether the patient has the reduced blood flow condition is received as a machine learning output of the trained machine learning model. The indication of whether the patient has the reduced blood flow condition is provided.
Patent WO-2023059439-A1 (WO)
Title: Apprentissage progressif sensible au matériel de modèles d'apprentissage machine
Inventor: LI SHENG
IPC: G06N3/08
Filed: 2022-09-21
Abstract: Des aspects de l'invention concernent l'entraînement progressif sensible au matériel de modèles d'apprentissage machine. Un système d'entraînement entraîne un modèle en fonction d'un processus d'apprentissage et de différentes valeurs spécifiées dans un programme d'apprentissage pour des réglages de performance à la fois niveau matériel et niveau modèle. Des réglages de performance niveau matériel peuvent provoquer des caractéristiques matérielles de ressources informatiques utilisées pour entraîner le modèle de façon à ce que celui-ci soit activé, désactivé, ou modifié au niveau de divers points pendant l'entraînement. Des réglages de performance niveau modèle peuvent prendre diverses valeurs pour ajuster les caractéristiques du modèle d'apprentissage machine qui sont entraînés ou du processus d'entraînement, pendant différents stades d'entraînement. Le système d'entraînement peut identifier et appliquer des valeurs complémentaires de paramètres de performance niveau matériel et niveau modèle pour générer des programmes d'entraînement qui améliorent la vitesse d'entraînement de modèle à des stades précoces d'entraînement, tout en améliorant la qualité du modèle à des stades ultérieurs d'entraînement.
Patent WO-2023122045-A1 (WO)
Inventor: CHEN SUET NEE
IPC: A61K38/17
Filed: 2022-12-19
Abstract: La présente invention divulgue des méthodes et des compositions destinées à traiter une cardiomyopathie dilatée. Dans des modes de réalisation, les méthodes et les compositions sont efficaces pour inhiber la signalisation PDGFRA.
Patent WO-2022183171-A1 (WO)
Title: Conductor cable and method
Inventor: FRANCO JUAN
IPC: G02B6/44
Filed: 2022-02-18
Abstract: A cable core including a body, a recess in the body, and a protrusion extending radially outwardly from the body and along the recess. A cable including a cable core having a body, a recess in the body, and a protrusion extending radially outwardly from the body and along the recess, a cladding disposed radially outwardly of the cable core and having an inside diameter in loaded contact with the protrusion, and a conductor disposed in the recess.
Patent WO-2022232828-A1 (WO)
Title: Semi-closed cycle aero engine with contrail suppression
Inventor: LEAR WILLIAM E
IPC: F02B37/00
Filed: 2022-04-29
Abstract: Various embodiments relate to a system and method of suppressing contrails emitted from an aircraft. One such system comprises a semi-closed cycle gas turbine engine of an aircraft that exhausts gases in use; a recuperator component that is positioned within an exhaust gas stream of the semi-closed cycle gas turbine engine to remove a portion of the exhaust gas stream in a form of heat energy; and one or more additional heat exchangers in a recirculation path that are configured to condense the heat energy of the portion of the exhaust gas to remove water vapor from the exhaust gas stream. Other systems and methods are also provided.
Patent WO-2023224665-A1 (WO)
Inventor: ALAKUIJALA JYRKI ANTERO
IPC: G10L19/022
Filed: 2022-05-17
Abstract: A method including receiving a formatted data packet including a compressed frequency-domain audio signal and a power coefficient, decompressing the compressed frequency-domain audio signal, transforming the decompressed frequency-domain audio signal into a blocked time-domain audio signal, modifying an initial blocking window based on a power coefficient to generate a modified blocking window, and generating a reconstructed time-domain audio signal based on the blocked time-domain audio signal using the modified blocking window.
Patent WO-2023279101-A1 (WO)
Title: Détermination à distance du débit de liquide céphalorachidien dans une dérivation ventriculo-péritonéale
Inventor: SAYANI SALEEM
IPC: A61B5/03
Filed: 2022-07-01
Abstract: L'invention concerne une méthode de surveillance du débit de liquide céphalorachidien (LCR) dans une dérivation ventriculo-péritonéale (DVP) implantée dans le corps d'un patient humain, consistant : (1) à recevoir, au niveau d'un dispositif externe au patient humain, des données détectées par une pluralité de capteurs à l'intérieur du dispositif, et positionné par rapport à la DVP pour drainer l'excès de LCR du cerveau du patient humain ; (2) à déterminer le débit de LCR dans la DVP, au moyen du dispositif et en fonction des données détectées ; et (3) à transmettre (sans fil, par exemple) à un serveur informatique des données indiquant le débit, au moyen du dispositif.
Patent WO-2023015206-A1 (WO)
Title: Method of treating posttraumatic stress disorder
Inventor: BABSON KIMBERLY
IPC: A61P25/18
Filed: 2022-08-03
Abstract: This disclosure provides methods for treating a disease or disorder by administering pharmaceutical compounds. In particular, the disclosure relates to treating posttraumatic stress disorder in an individual in need thereof by administering a fatty acid amid hydrolase inhibitor or a pharmaceutically acceptable salt thereof.
Patent WO-2023015217-A1 (WO)
Title: Use of cd4-targeted viral vectors
Inventor: CIARLO CHRISTIE
IPC: C12N15/87
Filed: 2022-08-03
Abstract: Provided herein are methods of transducing resting or non-activated T cells using CD4-targeted viral vectors.
Patent WO-2023019165-A1 (WO)
Title: Modulation of bcl-2 to enhance chimeric antigen receptor cancer immunotherapy efficacy
Inventor: RUELLA MARCO
IPC: C07K14/47
Filed: 2022-08-10
Abstract: The present disclosure provides modified cell(s), i.e., immune cell(s) or precursor cell(s) thereof, wherein the cell(s) are engineered to express a) a chimeric antigen receptor (CAR), and b) a variant of a B-cell lymphoma 2 (Bcl-2) family protein, wherein the variant confers resistance to a cytotoxic inhibitor of the Bcl-2 family protein. Also provided are methods and uses of the modified cells,  e.g.,  for treating at least one sign and/or symptom of cancer. Related nucleic acids, vectors, and pharmaceutical compositions are also provided.
Patent WO-2023076969-A1 (WO)
Title: Current information sharing of constant-on-time point-of-load converters
Inventor: JAYARAJ VINIT
IPC: G06F1/26
Filed: 2022-10-26
Abstract: This disclosure relates to current information sharing of constant-on-time (COT) point-of-load converters (Pols). Point-of-load converters (Pols) are generally used in distributed power architectures (DPAs) to step down a relatively high power distribution bus voltage to the lower voltages needed by system components such as microprocessors, Application-Specific Integrated Circuits (ASICs), and other digital integrated circuits (ICs). A multi-phase constant-on-time (COT) system includes a first point-of-load converter configured to provide a first current and a second point-of-load converter configured to provide a second current, and a bus configured to exchange information between the first point-of-load converter and the second point-of-load converter.
Patent WO-2023122723-A1 (WO)
Title: Panels and methods for diagnosing and treating lung cancer
Inventor: GEFFEN YIFAT
IPC: C12Q1/6886
Filed: 2022-12-22
Abstract: The invention provides molecular classifiers for use in the characterization and diagnosis of lung cancer and methods of selecting and treating subjects with appropriate personalized cancer treatments, including but not limited to CDK4/6 inhibitors, c-Met inhibitors, PD-1/PD-L1 inhibitors and combinations thereof.
Patent WO-2023129969-A1 (WO)
Inventor: KAPLAN TOMER
IPC: C12Q1/6881
Filed: 2022-12-28
Abstract: La présente divulgation concerne de manière générale des compositions et des procédés permettant de déterminer un type de cellule sur la base d'un profil de méthylation d'ADN associé. Pour l'ADN acellulaire, une telle détermination peut être utilisée pour identifier une maladie ou des états pathologiques relatifs au type de cellule. Pour des cellules tumorales, cette détermination étant utile pour identifier leur origine primaire.
Patent WO-2023133275-A1 (WO)
Inventor: RONAI ZE'EV A
IPC: A61K31/7105
Filed: 2023-01-06
Abstract: L'invention concerne des composés et des procédés pour inhiber la signalisation métabolique facilitée par la glutaryl CoA déshydrogénase (GCDH) pour le traitement du mélanome. Dans certains modes de réalisation, les composés peuvent réduire l'expression de la protéine GCDH et réduire la progression du mélanome exprimant GCDH.
Patent WO-2023164278-A1 (WO)
Inventor: MEDEIROS DANIEL
IPC: H02P1/02
Filed: 2023-02-28
Abstract: A power tool including a housing, a trigger, a motor coupled to an output member, and a motor drive circuit coupled to the motor. The power tool further includes a motor controller coupled to the motor drive circuit. The motor control circuit is configured to detect an input received from a sensor indicating that a wake-up operation is required. The motor control circuit is also configured to determine whether the power tool is in a sleep condition and initiate the wake-up operation in response to receiving the input and determining that the power tool is in the sleep condition.