baber/WOPTO huggingface dataset:
Patent CA-2519993-C (CA)
Title: Ph-dependent polypeptide aggregation and its use
Inventor: ZAHN RALPH
IPC: G01N33/68
Filed: 2004-03-23
Granted: 2011-02-15
Abstract: The invention provides an alternative method of reversible aggregation and/or dissociation of polypeptides. Proteins or polypeptides according to the invention have an inherent aggregation capability, wherein the aggregation is an oligomerization of the polypeptide that is based on the presence and the strucuture of peptide repeats localized in a flexibly disordered domain of this polypeptide. The flexibly disordered domain comprising the peptide repeats preferrably is located in close proximity with the N-terminus of the protein amino acid sequence. Preferably, each of the peptide repeats has a sequence that comprises one to four identical octapeptides with the amino acid sequence: PHGGGWGQ. Preferred proteins are selected from the group comprising cellular prion proteins (PrPc) and engineered polypeptides or fusion proteins with a respective inherent reversible aggregation and dissociation capability.  Because of the new mechanism of aggregation, the oligomerization reaction of the protein is reversible in a fluidic environment depending on the pH of this fluidic environment. Oligomerization occurs at a pH of 6.2 to 7.8, and the dissociation into monomers is reported to be at a pH range of 4.5 to 5.5.
Patent CA-2520485-C (CA)
Inventor: EMSLIE BRUCE STEVEN
IPC: A61K8/44
Filed: 2004-04-28
Granted: 2013-06-11
Abstract: Cosmetic stick compositions in the form of emulsions comprising a combination of amido structurants comprising in class (i) an N-acylaminoacid amide in which the N-acyl substituent has the formula -CO-RX in which RX represents a branched C6 to C11 alkyl group in combination with a further amido structurant, (class (ii), including a polyamido-substituted cyclohexane, an amido derivative of di or tricarboxylic acids or an hydroxy-stearamide and particularly employing an N-acylaminoacid amide in which the N-acyl substituent contains a linear alkyl group, or a cyclodipeptide.
Patent CA-2527897-C (CA)
Inventor: MINSKY STEVEN
IPC: G06F17/00
Filed: 2004-06-04
Granted: 2020-12-22
Abstract: In one aspect, the invention relates to a method to propagate relations between a first rule set and a second rule set wherein the first and second rule sets are invoked by a common workflow model. The method includes tracing paths forward through the workflow model from the first rule set to the second rule set. Enumerating relations that extend forward from the first rule set to the second rule set is another step in the method. Additionally, using multi-valued logic, calculating the effects on the relations of control flow through the workflow model from the first rule set to the second rule set, tracing paths backward through the workflow model from the second rule set to the first rule set, enumerating relations that extend backward from the second rule set to the first rule set, and using multi-valued logic, calculating the effects on the relations of control flow backwards through the workflow model from the second rule set to the first rule set are also steps in the method.
Patent CA-2531655-C (CA)
Inventor: FORSMAN BARLEY A
IPC: F16L37/084
Filed: 2004-07-08
Granted: 2009-02-17
Abstract: L'invention des systèmes d'hydratation personnels qui sont au moins partiellement ou intégralement formés de matières résistant au produits chimiques et/ou comprenant au moins un ensemble à branchement rapide. Ce système d'hydratation comporte un réservoir de fluide et peut être logé dans un emballage. Une boisson fluide est aspirée dans le réservoir et acheminée dans un tube à boisson jusqu'à un embout buccal. Dans certains modes de réalisation, ce système d'hydratation comporte un robinet de marche/arrêt actionné manuellement, un filtre, une pompe et un embout buccal actionné par morsure. L'ensemble à branchement rapide met en communication fluidique les composants du système d'hydratation et est configuré pour permettre une libération rapide et le rattachement des composants détachés ou de remplacement, ce qui permet l'obtention de performances différentes des composants détachés. Dans certains modes de réalisation, au moins une partie, voire l'intégralité du système d'hydratation est formée d'au moins une matière résistant aux produits chimiques. Dans certains modes de réalisation, le réservoir est formé d'au moins une matière thermoscellable et/ou multifeuilletée.
Patent CA-2538758-C (CA)
Inventor: PACIONE CHRISTOPHER
IPC: G06F/
Filed: 2004-09-13
Granted: 2014-10-28
Abstract: A nutrition and activity management system is disclosed that monitors energy expenditure of an individual through the use of a body-mounted sensing apparatus (10). The apparatus is particularly adapted for continuous wear. The system is also adaptable or applicable to measuring a number of other physiological parameters and reporting the same and derivations of such parameters. A weight management embodiment is directed to achieving an optimum or pre-selected energy balance between calories consumed and energy expended by the user. An adaptable computerized nutritional tracking system is utilized to obtain data regarding food consumed. Relevant and predictive feedback is provided to the user regarding the mutual effect of the user's energy expenditure, food consumption and other measured or derived or manually input physiological contextual parameters upon progress toward said goal.
Patent CA-2550802-C (CA)
Title: Hinge-lid type package for rod-like smoking articles and a blank therefor
Inventor: TAMBO HITOSHI
IPC: B65D5/54
Filed: 2005-02-17
Granted: 2010-04-20
Abstract: A hinged lid type package for housing the inner pack (IP) of filter cigarette, comprising an outer body (10), a lid (12) for opening/closing the upper opening end (26) of the outer body (10), and a pair of connection tabs (36) connected with the upper opening end (26) through a break line (38), wherein the connection tabs (36) intrude into the lid (12) and adhere to the inner surface thereof when a package is manufactured, and the connection tabs (36) leave breaking traces (X) on both the outer body (10) and the lid (12) when they are broken along the break line(38).
Patent CA-2557504-C (CA)
Title: Combinatorial therapies for the treatment of neoplasias using the opioid growth factor receptor
Inventor: ZAGON IAN S
IPC: A61K31/7072
Filed: 2005-02-21
Granted: 2020-12-01
Abstract: The present invention relates to pharmaceutical compositions for treating neoplasias in an animal or human comprised of a carrier and therapeutically effective amounts of at least one chemotherapeutic agent along with the biotherapeutic endogenous pentapeptide Met-enkephalin, referred to as opioid growth factor. Also provided are methods of treating neoplasias in an animal or human in need of such treatment, comprising the administration to the animal or human therapeutically effective amounts of a pharmaceutical composition comprised of a carrier and therapeutically effective amounts of at least one neoplasia-treating agent, such as a chemotherapeutic agent or radiation, along with opioid growth factor.
Patent CA-2559699-C (CA)
Inventor: BOUYSSOU THIERRY
IPC: A61P11/00
Filed: 2005-04-18
Granted: 2012-06-19
Abstract: The invention relates to novel pharmaceutical combinations containing at least one active ingredient (2) in addition to at least one, preferably one, compound of general formula (1) wherein the radicals R1, R2 and R3 have the designations cited in the patent claims and in the description. The invention also relates to a method for producing said combinations and to the use thereof as medicaments
Patent CA-2562351-C (CA)
Title: A tension lift frame used as a jacking frame
Inventor: PATTON BART
IPC: E21B33/06
Filed: 2006-10-04
Granted: 2012-04-10
Abstract: An offshore oil well drilling assembly is provided that includes an offshore platform; and a tension lift frame, which supports a coiled tubing injector and a blow out preventer connected thereto and for further connection to a wellhead, wherein the tension lift frame is a free standing assembly that is supported by the platform.
Patent CA-2570823-C (CA)
Title: Anticorps anti-recepteur aux interferons alpha 1 et leurs utilisations
Inventor: CARDARELLI JOSEPHINE M
IPC: C12P21/08
Filed: 2005-06-20
Granted: 2015-02-24
Abstract: La présente invention concerne des anticorps monoclonaux humains isolés, se liant au récepteur IFNAR-1 et capables d'inhiber l'activité biologique d'interférons de type I. L'invention concerne également des immunoconjugués, des molécules bispécifiques et des compositions pharmaceutiques comprenant lesdits anticorps. Cette invention se rapporte en outre à des procédés pour inhiber des troubles médiés par des interférons de type I au moyen des anticorps de l'invention, y compris des procédés pour traiter les maladies autoimmunes, le rejet de greffon ou la maladie du greffon contre l'hôte au moyen desdits anticorps.
Patent CA-2572656-C (CA)
Inventor: GREGORY MAX HOWARD
IPC: C08J3/03
Filed: 2006-12-29
Granted: 2012-07-17
Abstract: La présente invention concerne une méthode et une formulation permettant de fixer la viscosité de formulations de latex renfermant des cendres volantes. La formulation est une dispersion aqueuse contenant de l'eau, au moins un latex polymérique, entre environ 50 et environ 600 parties en poids de cendres volantes par 100 parties en poids de polymère sec, et une formulation stabilisant la viscosité qui, de préférence, renferme au moins un borate. La méthode consiste à ajouter la formulation stabilisant la viscosité à une formulation aqueuse de latex polymérique contenant des cendres volantes. La formulation stabilisant la viscosité peut être utilisée pour obtenir une dispersion aqueuse dont la viscosité à l'état mélangé, 7 jours après le mélange, est moins de 30 % supérieure à la viscosité de la formulation aqueuse tout de suite après le mélange.
Patent CA-2575274-C (CA)
Title: System for attenuation of water bottom multiples in seismic data recorded by pressure sensors and particle motion sensors
Inventor: BORRESEN CLAES NICOLAI
IPC: G01V1/38
Filed: 2005-08-23
Granted: 2011-11-22
Abstract: An up-going wavefield and a down-going wavefield are calculated at a sensor position from a pressure sensor signal and a particle motion sensor signal (43, 44). Then, an up-going wavefield is calculated at a water bottom position substantially without water bottom multiples from the up-going and down-going wavefields at the sensor position. In one embodiment, the up-going wavefield at the sensor position is backward propagated to the water bottom, resulting in an up-going wavefield at the water bottom (45). The down-going wavefield at the sensor position is forward propagated to the water bottom, resulting in a down-going wavefield at the water bottom (46). The up-going wavefield at the water bottom without water bottom multiples is calculated from the backward propagated up-going wavefield at the water bottom, the forward propagated down-going wavefield at the water bottom, and a reflection coefficient of the water bottom (48).
Patent CA-2577238-C (CA)
Title: An outflow regulator for a gravity-fed liquid outlet
Inventor: MALENFANT MARC-ANDRE
IPC: E03F7/02
Filed: 2005-08-11
Granted: 2011-03-22
Abstract: An outflow regulator for a gravity-fed liquid outlet of a liquid reservoir comprising a restriction plate mountable within the liquid outlet for limiting a flow rate of an effluent. The restriction plate allows a lower passage for the effluent when a first level of liquid is reached within the liquid reservoir, and an upper passage for the effluent when a second level of liquid is reached. The regulator also comprises a flapgate pivotable between a closed position where the flapgate covers the lower passage of the restriction device and an open position away from the restriction plate. When the flapgate is in the closed position, the effluent is free to flow out though the upper passage. A float counterweight switches the flapgate between the opened position and closed position according to the liquid level in the reservoir.
Patent CA-2580186-C (CA)
Inventor: VEXLER GAVRIEL
IPC: H01B11/02
Filed: 2007-03-02
Granted: 2014-10-07
Abstract: A telecommunications cable and separator spline are disclosed. In one embodiment the cable comprises a cable jacket defining an elongate cable core, a conductor assembly comprising four twisted pairs of conductors disposed along the core and a plurality of parallel elongate localised and like distensions in an inner surface of the cable jacket. The distensions are substantially evenly spaced about an inner surface of the cable jacket and prevent the conductor assembly from coming into contact with the inner surface. In particular embodiment, the distensions are the result of a series of filler elements placed between the cable jacket and the cable core and which wind helicoidally along and about the cable core. The separator spline is comprised of first and second elongate dividing strips having a substantially H shaped cross section and arranged side by side. The spline twists helicoidally along its length. In particular embodiment the separator spline and the insulation surrounding the twisted pairs of conductors is manufactured form a material having the same dielectric constant.
Patent CA-2582156-C (CA)
Inventor: MECHSNER KLAUS ALFONS
IPC: C22C21/06
Filed: 2005-09-30
Granted: 2014-05-27
Abstract: The present invention relates to a filler wire alloy composition comprising, in wt.%: Mg 6.0 to 9.5%, Mn 0.9 to 2.0%, Zn 0.2 to 0.9%, Zr <= 0.3%, preferably 0.05 to 0.25%, Cr <= 0.5%, Sc <= 2.8%, Cu <= 0.5%, preferably <= 0.25%, Fe <= 0.5%, Si <= 0.5%, Ti <= 0.3%, the balance aluminum and incidental elements and impurities. The invention further relates to a welded structure welded together with the present filler alloy and a method for constructing such a welded construction.
Patent CA-2582473-C (CA)
Title: Acoustic apparatus and telephone conversation apparatus
Inventor: SUGIURA TOMOHIRO
IPC: H04R3/02
Filed: 2006-01-31
Granted: 2010-10-26
Abstract: An acoustic apparatus has permanent magnets, which have north poles and south poles magnetized alternately in a stripe-like fashion, at the front and back of a diaphragm, respectively; and has a conductor circuit wired on the diaphragm along the stripe-like poles of the permanent magnets. This offers an advantage of being able to prevent an echo. The diaphragm, permanent magnets, conductor circuit, spacer and iron plates are installed in a baffle.
Patent CA-2596499-C (CA)
Inventor: WERTH STEFFEN
IPC: B01D53/32
Filed: 2006-01-23
Granted: 2013-10-01
Abstract: Composites comprising at least one hollow fibre of oxygen-transporting ceramic material, which is a ceramic material which conducts oxygen anions and electrons or a combination of ceramic material which conducts oxygen anions and a ceramic or nonceramic material which conducts electrons, with the outer surface of the hollow fibre being in contact with the outer surface of the same hollow fibre or another hollow fibre and the contact points being joined by sintering, are described. Further composites comprise at least one hollow fibre of oxygen-transporting ceramic material which is a ceramic material which conducts oxygen anions and electrons or a combination of ceramic material which conducts oxygen anions and ceramic or nonceramic material which conducts electrons and a connection element for the introduction or discharge of fluids at at least one end face, with hollow fibres and connection element being joined. The composites can be used for isolating oxygen from oxygen-containing gas mixtures or for carrying out oxidation reactions.
Patent CA-2602329-C (CA)
Inventor: SCHWARTZ MARC F
IPC: C12N5/02
Filed: 2006-03-24
Granted: 2016-08-09
Abstract: The present invention provides enhanced methods of producing soluble, active eukaryotic glycosyltransferases in prokaryotic microorganisms that have an oxidizing environment.
Patent CA-2603985-C (CA)
Title: Security or special paper with internal tactile recognition elements
Inventor: OLMOS RUIZ ANTONIO
IPC: B44F1/12
Filed: 2005-04-06
Granted: 2012-08-07
Abstract: Applicable to be used to issue notes of legal tender or any other type of document to facilitate its tactile recognition or prevent its falsification. It consists of a sheet of paper (1) in which expanding agents have been inserted (2), either centered heightwise or near the upper surface and/or lower surface thereof, forming a figure or inscription which, upon application of pressure and heat, either during the paper manufacturing phase or subsequent processes, cause the sheet of paper (1) to expand, thereby forming a curved and continuous embossing (3) on the surface of the document.
Patent CA-2604943-C (CA)
Title: Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same
Inventor: DUDLEY ROBERT E
IPC: A61K31/573
Filed: 2006-04-14
Granted: 2013-09-17
Abstract: A drug delivery system for oral administration of hydrophobic drugs with enhanced and extended absorption and improved pharmacokinetics is provided. In one embodiment, formulations comprising testosterone and testosterone esters, e.g., testosterone palmitate, are disclosed. Methods of treating a hormone deficiency or effecting male contraception with the inventive formulations are also provided.
Patent CA-2614588-C (CA)
Title: Procede et dispositif de mesure de la resistance
Inventor: KOBBE RICK ALLEN
IPC: G01R27/08
Filed: 2006-03-29
Granted: 2015-03-24
Abstract: L'invention concerne un dispositif conçu pour mesurer une résistance qui comporte un comparateur. Une bascule de type D a son entrée D reliée à la sortie du comparateur et son entrée de verrouillage reliée de façon à recevoir un signal d'impulsion à une vitesse de répétition d'impulsion fixe. Une source de tension témoin est reliée à une première entrée du comparateur et un intégrateur est couplé entre une sortie de la bascule et la seconde entrée dudit comparateur. L'intégrateur comporte une résistance qui lui permet de développer une tension au niveau de la seconde entrée du comparateur qui est fonction de la vitesse de répétition d'impulsion et de la résistance. Le comparateur, l'intégrateur et la bascule sont reliés en une boucle de rétroaction négative, ainsi, dans un état régulier, la tension développée par l'intégrateur à la seconde entrée du comparateur est sensiblement égale à la tension témoin.
Patent CA-2617396-C (CA)
Inventor: SHIOMI KAZUYUKI
IPC: B63H20/34
Filed: 2006-08-18
Granted: 2011-02-15
Abstract: A boat propulsion engine (1) comprises a main body (4) that extends substantially vertically in relation to a hull (Si), a lift generator (20) disposed in a rear portion of the main body (4), and supporting bodies (24) that support the lift generator (20) on the main body (4). The lift generator (20) has a surface (21g, 21h) that extends transversely relative to the main body (4) and that is located behind at least the main body (4). The supporting bodies (24) extend backward from the main body (4) to the lift generator (20) in a single vertical direction relative to a surface (21g, 21h) of the lift generator (20).
Patent CA-2617410-C (CA)
Inventor: CHOQUETTE YVES
IPC: G01B15/02
Filed: 2008-01-08
Granted: 2013-07-02
Abstract: A gamma monitoring apparatus and method for measuring water equivalent of snowpack over a selected ground area. A detector unit is installed at a given height above the area. The detector unit has a collimator and a scintillator coupled to a photomultiplier tube for detecting gamma rays emitted by naturally radioactive elements present in soil under the snowpack and absorbed by the snowpack in a field of view defined by the collimator. Pulses in a signal produced by the photomultiplier tube are measured and those exceeding threshold energy levels in a number of energy windows are registered as gamma counts. The water equivalent of the snowpack is periodically computed as functions of the gamma counts in the energy windows and the height of the detector unit with respect to ground level. The data representing the computed water equivalent are stored and controllably transmitted for reporting. Soil moisture content is also determinable.
Patent CA-2619887-C (CA)
Title: Filter device for molten metal filtration and method for producing such filters
Inventor: JUMA KASSIM
IPC: B22C9/08
Filed: 2006-09-04
Granted: 2012-06-05
Abstract: The present invention relates to a ceramic filter device for molten metal filtration comprising a major ceramic phase and a minor carbon phase bonded by phosphate bond, a method for producing such filter devices, and the use of such filter devices for the filtration of molten steel.
Patent CA-2623301-C (CA)
Title: Dispositif de joint d'etancheite a bascule et systeme pour le gonflage d'un pneumatique utilisant un tel dispositif
Inventor: REECE ROBERT
IPC: B60C25/12
Filed: 2006-10-02
Granted: 2012-07-24
Abstract: La présente invention a trait à un dispositif de gonflage (100, 200, 300, 400, 500, 600). Le dispositif de gonflage (100, 200, 300, 400, 500, 600) comporte un ensemble de joint d'étanchéité (102) qui maintient, tout en assurant l'étanchéité vis-à-vis de l'air ambiant (AP), un passage d'air ouvert (125) entre un talon (16) et un repos de talon (18) lors d'une opération de gonflage. L'invention a également trait à un joint d'étanchéité (106-106c) pour le dispositif de gonflage(100, 200, 300, 400, 500, 600). Le joint d'étanchéité (106-106c) comporte un élément de forme annulaire présentant une périphérie interne flexible (150-150c) qui est adapté au maintien, tout en assurant une étanchéité vis-à-vis de l'air ambiant (AP), un passage d'air ouvert (125) entre un talon (16) et un repos de talon (18) lors d'une opération de gonflage.
Patent CA-2625582-C (CA)
Inventor: COSTANTINI ANNE
IPC: A01K11/00
Filed: 2006-10-11
Granted: 2014-01-07
Abstract: The invention concerns an ear tag for identifying and marking animals, said tag associating a receiver button (1) by irreversible fitting of a finger (2). Said button (1) comprises a head (13) wherein is provided a cavity (8) for receiving a punch (3) of the finger (2). The head (13) is secured to a shell (5) retaining the punch (3) which is provided with an opening (6) for introducing the punch (3) inside the button (1). The axial wall (7) of the retaining shell (5) delimiting said opening (6) is radially deformable. A chamber (11) is arranged between the head (13) and said axial wall (7) for receiving the latter (7) deformed under the effect of the punch (3) passing through said opening (6).
Patent CA-2630571-C (CA)
Inventor: ITO MASASHI
IPC: B60L11/18
Filed: 2006-11-22
Granted: 2011-01-11
Abstract: A utility supply system (SS) supplies a fluid containing an antioxidant of a gaseous phase to a stack (1) of proton-exchange membrane fuel cells, for efficient removal of hydroxy radical.
Patent CA-2635420-C (CA)
Title: An automated media analysis and document management system
Inventor: SERJEANTSON BRETT
IPC: H04L12/16
Filed: 2008-01-29
Granted: 2010-07-13
Abstract: A web-based media analysis system, consisting of automated media analysis and document management tools, which processes news articles by parsing the news contents or documents and assigning, relating, and extracting information from the news contents for media analysis and relationally storing them in at least one database. The system further comprises a toning engine for toning articles accurately, based on words, attributes and categories of the article, and optionally based on the author of the article, if applicable.
Patent CA-2636077-C (CA)
Title: Thiazole compounds as protein kinase b (pkb) inhibitors
Inventor: ZENG QINGPING
IPC: A61P35/00
Filed: 2007-01-11
Granted: 2012-01-03
Abstract: The invention relates to thiazole compounds of Formula (I) and Formula (II) and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.