baber/WOPTO huggingface dataset:
Patent NZ-587096-A (NZ)
Title: Bicyclic nitroimidazoles covalently linked to substituted phenyl oxazolidinones
Inventor: DING CHARLES Z
IPC: A61K31/5365
Filed: 2009-03-25
Abstract: Disclosed is a compound of formula (I) where the substituents are as disclosed in the specification. Examples of compounds of formula (I) are: (S,S)-N-{ 3-[3-Fluoro-4-(4-{ 2-[4-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxymethyl)-phenoxy]-acetyl} -piperazin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl} -acetamide; (S,S)-N-(3-{ 3-Fluoro-4-[4-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxymethyl)-benzyloxy]-phenyl} -2-oxo-oxazolidin-5-ylmethyl)-acetamide and (S,S)-N-(3-{ 3-Fluoro-4-[3-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yloxymethyl)-benzyloxy]-phenyl} -2-oxo-oxazolidin-5-ylmethyl)-acetamide. Also disclosed is a pharmaceutical composition comprising a compound of formula (I).
Patent NZ-588471-A (NZ)
Title: Forms and Formulations of VX-950
Inventor: MURPHY MAURA
IPC: A61K45/06
Filed: 2005-06-08
Abstract: Disclosed herein are solid dispersion comprising VX-950 (telaprevir) and a polymer, particularly hydroxyproplymethylcellulose (HPMC) or hydroxypropylmethylcellulose acetate succinate (HPMCAS), wherein the solid dispersion is obtained by spray drying and a polymer is present in an amount from about 10% by weight to about 80% by weight. Said forms and formulations disclosed herein have improved bioavailability relative to crystalline VX-950 and are useful for treating HCV infection.
Patent NZ-588915-A (NZ)
Title: Use of cementitious slurry containing graphite and metakaolin in the production of synthesis gas by underground coal gasification
Inventor: BRANDL ANDREAS
IPC: C04B14/36
Filed: 2010-10-29
Abstract: A method of producing synthesis gas by the underground gasification of coal from a coal seam is disclosed, which comprises the steps of: (a) cementing casing string in a production well and an injection well which penetrates the coal seam by pumping into the wellbore a cementitious slurry and allowing the slurry to set to form a cement sheath in the wellbore; (b) igniting the coal in the coal seam;(c) introducing oxidant gas into the injection well; and(d) generating syngas as a combustion front in the coal seam and advancing the combustion front through the production well, wherein the temperature of the combustion front is greater than or equal to 800 Deg. C and further wherein the heat from the combustion front is distributed along the cement sheath in the wellbore, wherein the cementitious slurry comprises a cement mix comprising: (i) between from about 10 to about 70 weight percent of a cementitious material; (ii) between from about 5 to about 70 weight percent of graphite; and (iii) between from about 5 to about 70 weight percent of an aluminium silicate as metakaolin, wherein the density of the slurry is between from about 7.0ppg to about 23.00 ppg, the bottom hole static temperature of the production well at the time of slurry placement is less than or equal to 65 Deg. C.
Patent NZ-590215-A (NZ)
Title: Locator device extracts signals by detecting regular pulses appearing amongst averaged noise
Inventor: O BRIEN TIMOTHY GEORGE
IPC: H04B1/04
Filed: 2010-12-24
Abstract: Disclosed is a locator device (100) comprising a case (140), a display (130) for providing range and/or distance information between corresponding devices, a single ultrasonic transducer (110) for providing reception of signals and a processor. The processor is configured to detect a target signal transmitted from another device in the presence of background noise. This is done by periodically comparing a received signal to an average noise value of the environment to determine the occurrence of a transmitted pulse within the received signal. The presence of a target signal transmitted from the other device is then determined by correlating the presence of the pulse with the presence of at least one previous pulse determined within the received signal and occurring substantially one or more predetermined time intervals prior to the current pulse.
Patent NZ-591446-A (NZ)
Title: [6-(5-Ethoxymethoxy-benzofuran-2-yl)-2-nitro-pyridin-3-yl]-methyl-carbamic acid tert-butyl ester, [5-(5-ethoxymethoxybenzofuran-2-yl)-6-nitro-pyridin-2-yl]-methyl-carbamic acid tert-butyl ester and processes for their preparation
Inventor: BJORK SETH
IPC: A61K31/443
Filed: 2009-08-28
Abstract: Disclosed are the compounds [6-(5-ethoxymethoxy-benzofuran-2-yl)-2-nitro-pyridin-3-yl]-methyl-carbamic acid tert-butyl ester and [5-(5-ethoxymethoxy-benzofuran-2-yl)-6-nitro-pyridin-2-yl]-methyl-carbamic acid tert-butyl ester. Further disclosed are crystalline forms of the compounds, processes for their preparation and their use as a synthetic precursor for making labelled compounds, such as those wherein the label is an 18F atom, and particularly wherein said radio isotopically labelled compounds are selected from 2-(6-[18F]-fluoro-5-methylamino-pyridin-2-yl)-benzofuran-5-ol and 2-(2-[18F]-fluoro-6-methylamino-pyridin-3-yl)-benzofuran-5-ol or salts thereof.
Patent NZ-593183-A (NZ)
Title: System and method for storing items and tracking item usage
Inventor: NGUYEN THUY T
IPC: G16H40/63
Filed: 2006-12-06
Abstract: A system for storing items and tracking item usage comprises a tray (38) having a plurality of storage spaces for storing items. The one or more of the storage spaces have partitions (52) that are user-adjustable. The system further has a control unit (18) configured to store storage space-specific information and item specific information, and configured to generate transaction records; and a graphical user interface (22) in communication with the control unit. The graphical user interface includes a user-defined touch-sensitive image representative of the storage space-specific information stored by the control unit and for inputting and editing storage space-specific information.
Patent NZ-595628-A (NZ)
Title: Substituted nicotinamides as kcnq2/3 modulators
Inventor: KUHNERT SVEN
IPC: A61K31/4436
Filed: 2010-03-11
Abstract: The invention relates to substituted nicotinamides of general formula (1), in which A1 represents CR10R11 or S; A2 represents CR12R13, C(=O), O, S, S(=O), or S(=O)2; R1 represents saturated or unsaturated, branched or linear, unsubstituted, monosubstituted, or polysubstituted C1-10-alkyl or C2-10-heteroalkyl; saturated or unsaturated, unsubstituted, monosubstituted, or polysubstituted C3-10-cycloalkyl or heterocyclyl; unsubstituted, monosubstituted, or polysubstituted aryl or heteroaryl; saturated or unsaturated, unsubstituted, monosubstituted, or polysubstituted C3-10-cycloalkyl or heterocyclyl bridged by C1-8-alkyl or C2-8-heteroalkyl, wherein the alkyl chain or heteroalkyl chain can be branched or linear, saturated or unsaturated, unsubstituted, monosubstituted, or polysubstituted; or unsubstituted, monosubstituted, or polysubstituted aryl or heteroaryl bridged by C1-8-alkyl or C2-8-heteroalkyl, wherein the alkyl chain or heteroalkyl chain can be branched or linear, saturated or unsaturated, unsubstituted, monosubstituted, or polysubstituted; R9 represents saturated or unsaturated, unsubstituted, monosubstituted, or polysubstituted C3-10-cycloalkyl or heterocyclyl; unsubstituted, monosubstituted, or polysubstituted aryl or heteroaryl; or CRcRd. The invention also relates to methods for the production thereof, medicaments containing said compounds, and the use of said compounds for producing medicaments suited to treating pain, epilepsy, anxiety, dependency, mania, bipolar disorders, migraine, cognitive diseases, dystonia-associated dyskinesias and/or urinary incontinence. Examples of such compounds include: N-(3-Methyl-butyl)-2-[[1-methyl-3-[3-(trifluoromethyl)phenyl]-propyl]sulfanyl]-pyridine-3-carboxylic acid amide, 2-[3-(4-Fluorophenyl)-propylsulfanyl]-N-(2-methoxy-3,3-dimethyl-butyl)-pyridine-3-carboxylic acid amide, 2-[3-(4-Fluorophenyl)-propylsulfanyl]-N-[3-(1H-[1,2,4]triazol-1-yl)-propyl]-pyridine-3-carboxylic acid amide, 2-[3-(4-Fluorophenyl)-propylsulfanyl]-N-[(3-morpholin-4-yl-phenyl)-methyl]-pyridine-3-carboxylic acid amide, 2-[3-(4-Fluorophenyl)-propylsulfanyl]-N-(2-pyridin-4-yl-ethyl)-pyridine-3-carboxylic acid amide and 2-(2-Phenylsulfanyl-propylsulfanyl)-N-(thiophen-2-yl-methyl)-pyridine-3-carboxylic acid amide
Patent NZ-596429-A (NZ)
Title: Oil-in-water emulsion of mometasone and propylene glycol
Inventor: MOREN ANNA KARIN
IPC: A61K9/00
Filed: 2010-05-12
Abstract: 596429 Disclosed herein is an oil-in-water emulsion comprising mometasone or mometasone furoate and propylene glycol, wherein the concentration of propylene glycol is from about 20 to about 45% w/w, and wherein a part of mometasone or mometasone furoate is present in undissolved form. Additionally disclosed is the emulsion further comprising an oil, such as a vegetable oil; emulsifying agents, such as glycerol alkyl esters; a pH adjusting agent; and a viscosity-increasing agent, such as a fatty alcohol.
Patent NZ-601946-A (NZ)
Title: Methods of modifying antibodies, and modified antibodies with improved functional properties
Inventor: URECH DAVID
IPC: A61K39/395
Filed: 2008-06-25
Abstract: Disclosed are methods of using sequence based analysis and rational strategies to modify and improve the structural and biophysical properties of immunobinders, and in particular of single chain antibodies (scFvs), including such properties as stability, solubility, and/or antigen binding affinity. The invention provides methods of engineering immunobinders, and in particular scFvs, by performing one or more substitutions at amino acid positions identified by analysis of a database of selected, stable scFv sequences, wherein preferred amino acid residues for substitution have been identified. The invention also provides immunobinders prepared according to the engineering methods of the invention. The invention also provides preferred scFv framework scaffolds, into which CDR sequences can be inserted, as well as scFv antibodies made using these preferred framework scaffolds.
Patent NZ-603888-A (NZ)
Title: A modular ducting section adapted for laying end-to- end and side by side forming a networked utilities ducting system and rain and run-off water management system
Inventor: DIXON GUY ANDREW COTTERILL
IPC: E01C11/22
Filed: 2011-07-29
Abstract: A modular ducting section 10 adapted for laying end-to-end, comprises a base portion, two or more side walls extending upwardly from the base portion, the base portion and the two or more side walls defining one or more open-topped utility channels 20 adapted for carrying one or more utility lines, and an open-topped catchment channel 30 adapted for carrying water. The open-topped catchment channel 30 is not in liquid communication with the one or more open-topped utility channels 20. The open-topped catchment channel 30 is defined by a catchment channel wall extending outwardly and then upwardly from a side wall of one of the one or more open-topped utility channels. A supply channel is defined by the base portion, the side wall and an underside of the catchment channel wall.
Patent NZ-610705-A (NZ)
Title: Methods of treatment using lipid compounds
Inventor: HOVLAND RAGNAR
IPC: C07C57/03
Filed: 2011-11-03
Abstract: Disclosed is the use of a pharmaceutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt or ester thereof, in the manufacture of a medicament for treating or preventing elevated Apo B, primary hypercholesterolemia, and/or primary dysbetalipoproteinemia, wherein R1 and R2 are independently chosen from a hydrogen atom or linear, branched, and/or cyclic C1-C6 alkyl groups, with the proviso that R1 and R2 are not both hydrogen.
Patent NZ-614457-A (NZ)
Title: Transport and presentation box
Inventor: ORGELDINGER WOLFGANG
IPC: B65D25/30
Filed: 2009-11-17
Abstract: A box such as a bottle crate (10, 10a) is disclosed comprising a floor and at least two pairs of respectively opposing side walls. A first of the side walls (16b) extends from the floor by a removal height that is lower than the height of one or several of the other side walls in order to allow access to and removal of products contained in the box. The side walls adjacent the first wall (16b) each include a grip opening (28a) having a horizontal portion (50a) and a substantially vertical portion (50b) merged in a curve. The handle (28a) is arranged so that the box can be tilted backwards when carried to prevent bottles tipping out.
Patent NZ-619033-A (NZ)
Title: An integration system
Inventor: DONAGHEY ANDREW PAUL
IPC: H04L29/06
Filed: 2012-06-25
Abstract: Disclosed is an integration system for enabling communication between at least one service provider and end-devices. The integration system comprises a database (312) maintaining data on end-devices, an application kiosk (308) storing application files for the end-devices, a user interface (301) enabling access to the system by users and a services interface (302) for uploading applications to the application kiosk (308). The application files comprises (i) a profile for an application representing functional capabilities of the respective application and comprising available commands for respective devices; and (ii) a policy including configuration data for a deployment environment. The services interface (302) is further configured for deploying applications from the application kiosk (308) to a plurality of end-devices based on user requests and the respective application policies and communicating with the deployed applications using commands defined in the respective application profiles of the applications.
Patent NZ-624695-A (NZ)
Title: Enhancing diagnosis of disorder through artificial intelligence and mobile health technologies without compromising accuracy
Inventor: WALL DENNIS
IPC: G16H40/63
Filed: 2012-10-23
Abstract: A computer implemented method and computer system for generating a diagnostic tool for diagnosis of a behavioural disorder of a subject by applying machine learning to a diagnostic instrument for diagnosis of the behavioural disorder are disclosed. The diagnostic instrument comprises a set of diagnostic questions and corresponding selectable answers. The computer system comprises one or more processors; and memory to store: one or more computer programs. The one or more computer programs comprising instructions for receiving as input diagnostic outcomes and selected answers to the set of diagnostic questions of a plurality of subjects previously evaluated for the behavioural disorder, analysing the diagnostic outcomes and the selected answers of the plurality of previously evaluated subjects with the machine learning to construct a behavioural classifier to distinguish among previously evaluated subjects with different diagnostic outcomes with the behavioural classifier comprising a subset of the set of diagnostic questions and corresponding selectable answers from the diagnostic instrument, determining the accuracy of the behavioural classifier comprising the subset of diagnostic questions and corresponding selectable answers, by testing the behavioural classifier against an independent source of clinical data where the behavioural classifier comprising the subset of diagnostic questions and corresponding selectable answers has an accuracy over 90%, generating the diagnostic tool for diagnosis of the behavioural disorder, where the diagnostic tool comprises the behavioural classifier and the subset of diagnostic questions and corresponding selectable answers having the accuracy greater than 90%, and configuring a computing device accessible by a user to display the subset of diagnostic questions and corresponding selectable answers to the user, to collect user selected answers for the subset of diagnostic questions, and to provide the user selected answers as input into the behavioural classifier in order to diagnose the behavioural disorder of the subject with the behavioural classifier
Patent NZ-628457-A (NZ)
Title: Aerosol-generating article having a flavour-generating component
Inventor: MEYER CÉDRIC
IPC: A24D3/17
Filed: 2012-12-28
Abstract: An aerosol-generating article (10) comprises a plurality of elements assembled in the form of a rod (11). The plurality of elements includes an aerosol-forming substrate (20), and a mouthpiece filter (50) located downstream from the aerosol-forming substrate (20) within the rod (11). The aerosol-generating article (10) further comprises a volatile flavour-generating component (45) disposed between the aerosol-forming substrate (20) and the mouthpiece filter (50) within the rod (11). In some embodiments the volatile flavour-generating component (45) is supported by a low resistance support element (40) located between the aerosol-forming substrate (20) and the mouthpiece filter (50). In some embodiments the volatile flavour-generating component (45) is menthol.
Patent NZ-709828-A (NZ)
Title: Humanized monoclonal antibodies and methods of use for the diagnosis and treatment of colon and pancreas cancer
Inventor: WANG XUE-PING
IPC: G01N33/574
Filed: 2013-12-30
Abstract: This invention relates to humanized antibodies that selectively bind the 31.1 epitope on the A33 protein differentially expressed in cancers including, lung cancer, ovarian cancer, pancreas cancer, breast cancer and colon cancer, and diagnostic and therapeutic usages.
Patent NZ-711611-A (NZ)
Title: Compositions and methods of use for determination of he4a
Inventor: HELLSTROM KARL-ERIK
IPC: C12P21/04
Filed: 2011-02-17
Abstract: Disclosed is a monoclonal antibody that specifically binds to the N-WFDC domain of an HE4a polypeptide, wherein the antibody is selected from the group consisting of: (a) the monoclonal antibody produced by the hybridoma cell line 12A2, deposited with the ECACC as Patent Deposit No. 10091401; (b) a monoclonal antibody that binds to the amino acid sequence set forth in SEQ ID NO:17; (c) a monoclonal antibody that is an antigen binding fragment of a monoclonal antibody of (a) or (b), wherein the fragment specifically binds to the N-WFDC domain of an HE4a polypeptide.
Patent NZ-713294-A (NZ)
Title: Content creation tool
Inventor: MULLINS BRIAN
IPC: H04N21/80
Filed: 2014-03-12
Abstract: A server for content creation is described. A content creation tool of the server generates an experience content dataset using a template to process a content identifier and virtual object content, the template corresponding to an interactive feature for the virtual object content. An experience generator of the server provides the experience content dataset to a device that recognizes the content identifier, to generate an interactive experience with the virtual object content at the device.
Patent NZ-716514-A (NZ)
Title: Staple assembly
Inventor: YOUNG GRAEME
IPC: F16B15/06
Filed: 2014-07-21
Abstract: Barbed staples can allow stronger retainment of the staple in a workpiece. However, barbs on such staples meant that they are not suitable for power tools known in the art. Disclosed is an assembly of staples, the staples comprising a crown portion having at least two legs extending therefrom and one or more barbs protruding from at least one of the legs, wherein each barb comprises a truncated tip such that the tip of each barb is substantially flat, wherein the crown is configured in a shape including an arch, at an apex, merging into a straight section declining at an oblique angle to a centreline of a corresponding one of the legs, and the straight section merging into the legs via a curved section; and the assembly further comprising at least one strip of collation tape, wherein the staples are collated and connected by way of the at least one strip of collation tape secured to the staples.
Patent NZ-733731-A (NZ)
Title: 5-methoxytryptophan and its derivatives and uses thereof
Inventor: WU KENNETH KUN-YU
IPC: A61K31/405
Filed: 2016-01-13
Abstract: A 5-methoxytryptophan and its derivatives are disclosed, wherein the 5-methoxytryptophan and its derivatives are represented by the following formula (I): wherein R1, R2, R3, R4, R5, and n are defined in the specification. In addition, the present invention also provides uses of the 5-methoxytryptophan and its derivatives for treating inflammatory-related disease and cancers.
Patent NZ-742827-A (NZ)
Title: Vent arrangement for a respiratory device
Inventor: FOOTE ROGER MERVYN LLOYD
IPC: A61M16/20
Filed: 2014-03-14
Abstract: A system comprising a respiratory mask for delivering a supply of breathable gas to the entrance of a patient’s airways for amelioration or treatment of a respiratory disorder, the respiratory mask having venting apparatus configured to vent a plenum chamber of the respiratory mask to ambient, the venting apparatus comprising: a first adjustable vent; a second adjustable vent; and actuator apparatus on the mask to (1) automatically vary the first adjustable vent in response to a first control system signal for adjusting the first adjustable vent, and (2) to automatically vary the second adjustable vent in response to a second control system signal for adjusting the second adjustable vent; the system further comprising: a controller adapted to couple with the actuator apparatus and generate the first control system signal and the second control system signal, and wherein each of the first adjustable vent and the second adjustable vent is controllable by the controller, wherein the controller is configured to control an operation of the actuator apparatus so as to alter an amount of flow of the breathable gas exiting each vent, and wherein the operation adjusts the first adjustable vent distinctly from the second adjustable vent by coordinating (a) an increase in an amount of a flow of the breathable gas exiting one of the first adjustable vent and the second adjustable vent, with (b) a decrease in an amount of flow of the breathable gas exiting the other one of the first adjustable vent and the second adjustable vent.
Patent NZ-745522-A (NZ)
Title: A laser coded fold wrapped food concentrate tablet
Inventor: WEIER DETLEF
IPC: B65B25/06
Filed: 2017-04-20
Abstract: A process for coding a fold wrapped food concentrate tablet comprising laser ablating a code on a packaging material comprising a printed plastic or paper film, and fold wrapping the tablet in the packaging material. After fold wrapping, the laser code is located visibly at an overlapping packaging area (2). The invention provides a fold wrapped food concentrate tablet that avoids using harmful substances in the coding, as well as the drying time and abrasion risk of ink coding, while providing a level of moisture permeability comparable to a non laser coded fold wrapped tablet.
Patent NZ-746394-A (NZ)
Title: Compositions and methods of use of an inappetance-controlling compound
Inventor: ZOLLERS BILL
IPC: A61K31/437
Filed: 2013-09-27
Abstract: The invention provides for a method of treating inappetance-induced weight loss in one or more companion animals or livestock. The method provides for administering a therapeutically effective amount of a capromorelin-containing composition to the companion animal or livestock. Optionally, one or more flavoring agents or flavor-masking agents can be added to the capromorelin-containing composition to enhance or mask the flavoring of the composition for the companion animal or livestock.