baber/WOPTO huggingface dataset:
Patent ES-2190895-B2 (ES)
Inventor: GARRIDO FERNANDEZ JUAN MANUEL
IPC: C02F3/12
Filed: 2002-02-01
Granted: 2004-05-16
Abstract: Hybrid membrane biological reactor (A) for treating industrial and domestic waste water comprises an anoxic chamber (1); aerobic chamber (2) and membrane-filtration chamber (3), the last with a rectangular cross-section or other geometrical shape.
Patent ES-2194604-B2 (ES)
Title: Composicion para su uso en la eliminacion de manchas superficiales en productos ceramicos, y procedimiento de elaboracion de dicha composicion.
Inventor: PANOS PICAZO ALFREDO
IPC: B28B11/22
Filed: 2002-04-11
Granted: 2004-12-16
Abstract: Composición para su uso en la eliminación de manchas superficiales en productos cerámicos, y procedimiento de elaboración de dicha composición. La composición es la siguiente: **FIGURA** El procedimiento de realización comprende la adición de agua y un producto dispersante a un recipiente agitador, adición de BaCO{sub,3}, adición a la mezcla de un producto antiespumante y un producto antiespesante, regulación de la proporción del producto antiespumante hasta alcanzar el % requerido, y adición de un producto retardador producto acticida de secado, y un producto humectante, regulación del pH hasta alcanzar un grado de 8-8,5 mediante la anexión de un álcali, y ajuste, en su caso, de la viscosidad, que incluye la adición de un agente dispersante y adición nuevamente de un álcali.
Patent ES-2246726-B2 (ES)
Title: Espuma de fosfato de calcio autofraguable e inyectable.
Inventor: GINEBRA MOLINS MARIA PAU
IPC: A61K6/838
Filed: 2004-08-12
Granted: 2007-11-01
Abstract: Espuma de fosfato de calcio autofraguable e inyectable. Se propone la obtención una espuma de fosfato de calcio autofraguable e inyectable para ser utilizada como biomaterial para regeneración ósea y/o como sustrato para la ingeniería de tejidos. La vía que se propone es el espumado de un cemento de fosfato de calcio mediante la adición de surfactantes y la agitación o batido mecánico del mismo. La adición del surfactante permite estabilizar burbujas de aire en la matriz del cemento, consiguiéndose una elevada macroporosidad, con interconexión entre los poros. La obtención de macroporosidad es de gran importancia para la regeneración ósea, porque facilita la angiogénesis, la colonización del material por el tejido óseo y su reabsorción. Teniendo en cuenta las aplicaciones del material, es especialmente relevante la selección de surfactantes biocompatibles. En este sentido se proponen surfactantes aprobados para sistemas de dosificación de fármacos por vía parenteral.
Patent ES-2293814-B2 (ES)
Title: Producto de aleacion de aluminio de alta tolerancia al daño para, en particular, aplicaciones aeroespaciales.
Inventor: HARGARTER HINRICH J W
IPC: B64C3/26
Filed: 2004-06-03
Granted: 2009-10-02
Abstract: Producto de aleación de aluminio de alta
tolerancia al daño para,  en particular, aplicaciones
aeroespaciales. 
     Un producto labrado de aleación de aluminio con
gran resistencia y elevada tenacidad a  la rotura y elevada
resistencia a la fatiga y bajo índice de desarrollo de grietas por
fatiga,  y que tiene una composición de (en % en peso): 0,3 a 1,0%
de Mg, 4,4 a 5,5% de Cu, 0 a  0,20% de Fe, 0 a 0,20% de Si, 0 a
0,40% de Zn y Mn en un intervalo de 0,15 a 0,8 como  elementos que
forman fases dispersas, en combinación con uno o más elementos que 
forman fases dispersas seleccionados del grupo que consiste en Zr,
Sc, Cr, Hf, Ag, Ti,  V, siendo el resto aluminio (Al) y otros
elementos incidentales, y en donde existe una  limitación del
contenido de Cu-Mg de modo que: -1,1[Mg] +
n[Cu] \leq 5,5. El invento se  refiere, además, a un método
para fabricar un producto de este tipo.
Patent ES-2338201-B2 (ES)
Title: Dispositivo de asistencia a la conduccion.
Inventor: GARCIA MANCHADO NILO
IPC: B60R16/02
Filed: 2008-11-03
Granted: 2011-02-07
Abstract: Dispositivo de asistencia a la conducción que
comprende, al menos unos primeros medios de posicionamiento global
configurados para proporcionar la posición y velocidad del vehículo;
y 
     unos segundos medios de almacenamiento de datos,
configurados para almacenar los parámetros básicos del vehículo,
siendo dichas características, al menos, marca y modelo, carga en
vacío y comportamiento nominal del motor; 
     donde, una vez el usuario ha definido el
vehículo a conducir en dicha base de datos, así como si el vehículo
está en alta ocupación o baja ocupación, se muestra la distancia de
anticipación en unos medios de visualización propios del
dispositivo, siendo definida dicha distancia como el espacio/tiempo
que recorre el propio vehículo con consumo de combustible cero; 
     y comprendiendo, además, medios de cálculo de la
aceleración y deceleración ecológica del vehículo, donde una vez
conocida la aceleración del vehículo por los medios de
posicionamiento global, definido el vehículo, la ocupación del
mismo, el perfil de conducción y el perfil de conductor, se muestra
en los medios de visualización si dicha aceleración/deceleración es
óptima desde el punto de vista del consumo de combustible, indicando
al usuario, además, la relación óptima de marchas.
Patent ES-2400134-B2 (ES)
Title: Dispositivo y procedimiento para la cuantificación de la afectación arterial producida por la arteriosclerosis.
Inventor: VALVERDE VALVERDE JOSE MARIA
IPC: A61B5/00
Filed: 2011-05-27
Granted: 2013-10-14
Abstract: Dispositivo y procedimiento para la cuantificación de la afectación arterial producida por la arteriosclerosis.#Dispositivo para la determinación y evaluación del grado de afectación arterial en humanos por la arteriosclerosis, que comprende una pareja de brazaletes inflables (2, 12) acoplados a brazo y pierna respectivamente, donde sendos brazaletes comprenden respectivamente medios de inflado que comprimen dicha extremidad superior; sensores de presión (4, 9) encargado de medir la presión arterial de dicha extremidad superior; y electrodos (3, 10, 11) configurados para medir el pulso cardíaco del paciente para calcular la diferencia temporal entre el instante que ocurre el máximo de la onda R y los instantes de inicio de la onda de presión en extremidad superior e inferior; calcular la distancia entre el corazón del paciente y cada brazalete inflable (2, 12) y, por tanto, calcular la velocidad media de la onda de pulso en cada tramo, así como el índice tobillo-brazo de presiones.
Patent AU-2001289984-B2 (AU)
Title: Detachable device for gripping, lifting, handling and tilting cooking utensils with two handles
Inventor: DODANE PAUL
IPC: A47J45/07
Filed: 2001-09-03
Granted: 2006-06-08
Abstract: The removable device for taking hold of, lifting, handling, and pouring from cooking utensils having two diametrically opposite outwardly-directed handles in the form of lugs (2), each of which has an opening (5) that is substantially parallel to the inner edge (6) of said lug (2), is characterized by the fact that it comprises a pair of removable shells (10) suitable for fitting over said lugs (2) and made of a thermally insulating material, each shell (10) presenting an internal cavity (11), which opens out laterally through an oblong orifice (13), which is suitable for receiving a lug (2) inserted through said orifice (13), and which is fitted with an internal locking/unlocking device (20) suitable for co-operating with the opening (5) in the lug (2) when received in said cavity (11).
Patent AU-2002303187-B2 (AU)
Title: Process for the preparation of 2'-HALO-Beta-L-arabinofuranosyl nucleosides
Inventor: SZNAIDMAN MARCOS
IPC: C07H19/06
Filed: 2002-03-29
Granted: 2007-11-08
Abstract: The present invention is directed to the process for the preparation of 2'-deoxy-2'-halo-beta-L-arabinofuranosyl nucleosides, and in particular, 2'-deoxy-2'-fluoro-beta-L-arabinofuranosyl thymine (L-FMAU), from L-arabinose, which is commercially available and less expensive than L-ribose or L-xylose, in ten steps. All of the reagents and starting materials are inexpensive and no special equipment is required to carry out the reactions.
Patent AU-2002308562-B2 (AU)
Title: Recombinant tumor specific antibody and use thereof
Inventor: LO KIN-MING
IPC: C07K16/46
Filed: 2002-05-03
Granted: 2008-01-24
Abstract: The invention provides a family of antibodies that specifically bind the human epithelial cell adhesion molecule. The antibodies comprise modified variable regions, more specially, modified framework regions, which reduce their immunogenicity when administered to a human. The antibodies, when coupled to the appropriate moiety, may be used in the diagnosis, prognosis and treatment of cancer.
Patent AU-2002309974-B2 (AU)
Title: Method and apparatus for allocating resources in a multiple-input multiple-output (MIMO) communication system
Inventor: WALTON JAY R
IPC: H04J99/00
Filed: 2002-05-15
Granted: 2007-03-01
Abstract: Techniques to schedule downlink data transmission to a number of terminals in a wireless communication system. In one method, one or more sets of terminals are formed for possible data transmission, with each set including a unique combination of one or more terminals and corresponding to a hypothesis to be evaluated. One or more sub-hypotheses may further be formed for each hypothesis, with each sub-hypothesis corresponding to specific assignments of a number of transmit antennas to the one or more terminals in the hypothesis. The performance of each sub-hypothesis is then evaluated, and one of the evaluated sub-hypotheses is selected based on their performance. The terminal(s) in the selected sub-hypothesis are then scheduled for data transmission, and data is thereafter coded, modulated, and transmitted to each scheduled terminal from one or more transmit antenna assigned to the terminal.
Patent AU-2002319320-B2 (AU)
Title: Substituted isoxazoles and the use thereof as antibiotics
Inventor: ROCA CAROLINA SALCEDO
IPC: A61P35/00
Filed: 2002-07-17
Granted: 2008-03-06
Abstract: 3-(heterocyclyl-substituted aryl)-5-substituted-isoxazole derivatives (I) are new. 3-(heterocyclyl-substituted aryl)-5-substituted-isoxazole derivatives of formula (I), their stereoisomers or mixtures, different polymorphs or mixtures, N-oxides, solvates and salts are new. [Image] X : O, S, NH, OCO, NHCO, NHCOO, NHCS, NHCONH or NHCSNH; R 4>H, 1-3C alkyl (optionally substituted by 1-3 F, Cl or Br) or Het 1>; R 1>, R 3>H or F; Het 1>C-bound 5-membered ring having 1-4 N, O or S atoms and optionally substituted by NH 2, 1-4C alkyl, 1-4C alkoxy, 1-4C alkylamino, 1-4C alkoxycarbonyl, 1-4C alkylcarbonyl, amido, CN, NO 2, F, Cl or Br, or a 6-membered ring with 1-3 N, and optionally substituted by 1-3 F, Cl or Br; R 2>pyrrolidin-1-yl, 2-oxopyrrolidin-1-yl, 1,3,4-triazol-1-yl, tetrazol-1-yl, or pyrrol-1-yl or 1,2,4-triazol-1-yl (both 3-substituted by R 6>), or pyrazol-1-yl, imidazol-1-yl, 1,2,5-triazol-1-yl, 1,2,3-triazol-1-yl or tetrazol-1-yl (all 4-substituted by R 6>), or a group of formula (i)-(vi); Q : O, S(O) xor NR 5>; x : 0-2; R 5>-(CH 2) nCOR 7>, SO 2R 7>or a group of formula (vii)-(xii); Q 1>O or S; R 1>6>-R 1>8>COR 9>, COOR 9>, CN, NO 2or C=NR 1>0>; R 7>1-4C alkyl, 1-3C alkenyl (sic), -(CH 2) p-R' 2>, -(CH 2) m-Y-(CH 2) q-R 8>or Het 2>; n, p, q, m : 0-8; Y : O, S or NH; R' 2>R 2>excluding (ii); R 8>H, 1-3C alkyl, vinyl, allyl, ethynyl, propargyl, phenyl or an optionally fused aromatic system comprising one or more 5-6 membered rings, optionally including 1-3 O, S or N and optionally substituted by 1-3 T; T, R 1>3>-R 1>5>1-4C alkyl, 1-4C alkoxy, 1-4C alkylthio, NHCOR 9>, NHCOOR 9>, COR 9>, COOR 9>, CN, NO 2, CH=NR 1>0>, F, Cl or Br; R 9>H, 1-3C alkyl or NR 1>1>R 1>2>; R 1>1>, R 1>2>H or 1-3C alkyl; R 1>0>H, 1-3C alkyl, phenyl, benzyl, OH or 1-3C alkoxy; Het 2>a group of formula (xiii)-(xix); R 6>H, F, Cl, Br, CF 3, CN, NO 2, carbamoyl, hydroxymethyl, 1-3C alkyl, 1-3C alkoxy, 1-3C alkoxycarbonyl, 1-3C alkylcarbonyl, 1-3C alkoxy, benzyloxy-1-3C alkoxy, CONR 1>9>R 2>0>, NR 1>9>R 2>0>, 1-3C alkylamino, 1-3C alkyl-CH=NOR 2>1>, CH=NOR 21>, CH=CR 22>R 2>3>, (CH 2) sNHR 1>9>, or CH=NR 1>9>; R 1>9>, R 2>0>H, 1-3C alkyl, COR 2>4>or optionally fused aromatic system comprising one or more 5-6 membered rings, optionally including 1-3 O, S or N and optionally substituted by 1-3 T; R 2>1>H or 1-3C alkyl; R 2>2>, R 2>3>H, CN, NO 2, CONR 1>9>R 2>0>or hydroxymethyl; R 2>4>H, 1-3C alkyl or alkoxy or Het 2>; and s : 0-4. [Image] [Image] [Image] ACTIVITY : Antibacterial; Cytostatic. In tests to determine antibacterial activity, 3-[3-fluoro-4-(hydroxyacetyl)piperazin-1-yl-phenyl]-5-(isoxazol-3-yl-aminomethyl) isoxazole displayed MIC values of 4, 2 and 8 Microg/ml against Streptococcus faecalisBCM-010, Staphylococcus aureusBCM-012 and Moraxella catarrhalisBCM-015, respectively. MECHANISM OF ACTION : None given.
Patent AU-2003233739-B2 (AU)
Title: Method of manufacturing an engraved plate
Inventor: GIORI FAUSTO
IPC: B23K26/00
Filed: 2003-06-03
Granted: 2008-07-03
Abstract: The invention relates to a system for manufacturing an engraved plate for intaglio printing of sheets of security papers, said system comprising a computer and at least one engraving tool controlled by said computer in accordance with a programmed engraving process, wherein said computer is programmed to control the engraving tool in accordance with three-dimensional guiding pixel data (X, Y, Z) of a master depth-map of one said sheet to engrave a non engraved plate pixel by pixel, and wherein said master depth-map is generated on said computer on the basis of at least one original depth-map stored on said computer, said original depth-map consisting of a three-dimensional raster image of at least a part of one said security paper. The invention also relates to a system and method for generating said guiding data.
Patent AU-2003235910-B2 (AU)
Title: Multi-layer film and medicine container using the same
Inventor: OKAMOTO HIDESHI
IPC: B32B1/02
Filed: 2003-05-09
Granted: 2007-09-20
Abstract: ABSTRACT Disclosed is a multi-layer film comprising: a surface layer having a thickness of 10 to 50 fÊm made of an ethylene-f¿-olefin copolymer having a density of 0.935 to 0.950 g/cm3, a flexible layer having a thickness of 100 to 200 fÊm made of an ethylene-f¿-olefin copolymer having a density of 0.860 to 0.930 g/cm3, a barrier layer having a thickness of 10 to 80 fÊm made of a mixed resin containing 60 to 95% by weight of a cyclic olefin polymer and 5 to 40% by weight of an ethylene-f¿-olefin copolymer having a density of 0.900 to 0.965 g/cm3, and a seal layer having a thickness of 5 to 80 fÊm made of an ethylene-f¿-olefin copolymer having a density of 0.910 to 0.950 g/cm3. This multi-layer film is suited for use as a material for production of a medicine container 10 because it suppresses adsorption of a medicine by the barrier layer and is also superior in strength and flexibility.
Patent AU-2003246297-B2 (AU)
Title: A Refrigeration Source for a Cryoablation Catheter
Inventor: KUDARAVALLI RAVIKUMAR
IPC: A61F7/00
Filed: 2003-09-11
Granted: 2007-06-07
Abstract: A supply line (46) is positioned inside a lumen (50) of catheter tube. A precooler cools fluid refrigerant passing through proximal end (38) of supply line at a specified temperature (Pw) and flows out from distal end (36) of supply line into tip section (56) of catheter tube. An exhaust unit evaluates the fluid refrigerant from catheter tube and maintains a specified value of outflow pressure in the tip section. An independent claim is included for method for cooling tip section of cryoablation catheter.
Patent AU-2003277099-B2 (AU)
Title: Systems of sperm cell preservation and processing
Inventor: HOLLINSHEAD FIONA KATE
IPC: A61N/
Filed: 2003-09-15
Granted: 2009-10-29
Abstract: The preservation of sperm cells, and other processing of sperm cells, are disclosed. The present invention is directed in some embodiments to sperm cell preservation, as sperm cell preservation may further relate to artificial insemination, in vitro fertilization, super-ovulation, mammal production, sperm samples, and sperm cell processing, generally. The present invention is also directed in some embodiments to sperm cell processing features, such as collecting, handling, sorting, storage, transportation, use, fertilization, or insemination techniques. Sperm cell preservation in accordance with the present invention may address maintenance or enhancement of sperm quality, and in some embodiments one or more sperm cell characteristics, such as viability, motility, and functionality. Fertilization rates may also be maintained or enhanced.; An embodiment may comprise obtaining sperm cells (10). The sperm cells may be cryoperserved (20) and thawed (30). Processing (40) may be performed on the sperm cells and cryopreservation of the sperm cells (50).
Patent AU-2004206483-B2 (AU)
Title: Recording medium with copy protection information formed in intermittent or alternate wobbled pits and apparatus and methods for forming, recording, and reproducing the recording medium
Inventor: KIM JIN YONG
IPC: G11B20/12
Filed: 2004-01-20
Granted: 2008-06-26
Abstract: A recording medium including recorded data, comprising: a control data area including pits formed along tracks, with data recorded therein, wherein pits formed in some portions of the tracks are shifted from a track center to left and/or right to thereby form intermittent or alternate wobbled pits and wherein pits formed in other portions of the tracks of the control data area are substantially along the track center to thereby form straight pits, wherein the wobbled pits contain a key value for encrypting main data; and a data area adapted for storing main data encrypted by using the key value in straight pits.
Patent AU-2004246958-B2 (AU)
Title: 2-amino-9-(2-substituted ethyl)purines and preparing methods for 9-(4-acetoxy-3-(acetoxymethyl)but-1-yl)- 2- aminopurine using the same
Inventor: LEE BYOUNG-SUK
IPC: C07D473/32
Filed: 2004-06-12
Granted: 2010-09-16
Abstract: The present invention relates to a new compound of 2-amino-9-(2-substituted ethyl)purine and an effective method for preparing 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurin (famciclovir) using the same. The 2-amino-9-(2-substituted ethyl)purine according to the invention is represented by the following formula (II'): (Formula II') wherein R is a hydroxy, halogen, mesyloxy or tosyloxy group. The inventive method for the preparation of famciclovir comprises the steps of halogenating 2-amino-9-(2-substituted ethyl)purine to give 2-amino-9-(2-halogenoethyl)purine, and reacting the halogenated compound with diethylmalonate. The inventive preparation method allows famciclovir, a purine derivative drug with effective antiviral activity, to be prepared in a high selectivity of 100% in a pure form by using the inventive new compound of 2-amino-9-(2-substituted ethyl)purine. In addition, the inventive method allows the utilization of relatively mild reaction conditions, and thus, has high industrial process efficiency.
Patent AU-2004290023-B2 (AU)
Title: Cleaning compositions in the form of a tablet
Inventor: ZABARYLO STEVE
IPC: C11D3/37
Filed: 2004-11-05
Granted: 2009-12-24
Abstract: A cleaning composition in the form of a tablet or granule comprising defined amounts of alpha hydroxyl aliphatic acid; alkali metal bicarbonate; a clay; an anionic surfactant; alkali metal carbonate; a bleach compound; and an alkali metal salt of a polycarboxylic acid polymer.
Patent AU-2005205544-B2 (AU)
Title: Radio network relocation
Inventor: SIPILA JUHA P
IPC: H04W52/02
Filed: 2005-01-05
Granted: 2009-08-13
Abstract: There is disclosed a method for serving radio network subsystem relocation from a first radio network controller to a second radio network controller for an established call to a user equipment, comprising transmitting a transmission power control combination index of a radio link established between the user equipment and the first radio network controller to the second radio network controller.
Patent AU-2005219576-B2 (AU)
Title: Novel hydroxy-6-heteroarylphenanthridines and their use as PDE4 inhibitors
Inventor: CHRISTOF ZITT
IPC: C07D471/04
Filed: 2005-03-02
Granted: 2011-06-30
Abstract: Compounds of formula (I), in which R1 is hydroxyl, 1-4C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy, 2,2-difluoroethoxy, or completely or predominantly fluorine-substituted 1-4C-alkoxy, R2 is hydroxyl, 1-4C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy, 2,2-difluoroethoxy, or completely or predominantly fluorine-substituted 1-4C-alkoxy, or in which R1 and R2 together are a 1-2C-alkylenedioxy group, R3 is hydrogen or 1-4C-alkyl, R31 is hydrogen or 1-4C-alkyl, either, in a first embodiment (embodiment a) according to the present invention, R4 is -O-R41, in which R41 is hydrogen, 1-4C-alkyl, 1-4C-alkoxy-1-4C-alkyl, hydroxy-2-4C-alkyl, 1-7C-alkylcarbonyl, or completely or predominantly fluorine-substituted 1-4C-alkyl, and R5 is hydrogen or 1-4C-alkyl, or, in a second embodiment (embodiment b) according to the present invention, R4 is hydrogen or 1-4C-alkyl, and R5 is -O-R51, in which R51 is hydrogen, 1-4C-alkyl, 1-4C-alkoxy-1-4C-alkyl, hydroxy-2-4C-alkyl, 1-7C-alkylcarbonyl, or completely or predominantly fluorine-substituted 1-4C-alkyl, Har is optionally substituted by R6 and/or R7 and/or R8, and is a 5- to 10-membered monocylic or fused bicyclic unsaturated or partially saturated heteroaryl radical comprising 1 to 4 heteroatoms selected independently from the group consisting of oxygen, nitrogen and sulfur, are novel effective PDE4 inhibitors.
Patent AU-2005239772-B2 (AU)
Title: Foamed cleanser with suspended particles
Inventor: KERRY MATTHEWS SHAUN
IPC: C11D3/382
Filed: 2005-05-06
Granted: 2011-09-15
Abstract: One aspect of the invention is a new foam with particles suspended therein. Another aspect of the invention is a foaming component for use in association with a foam dispenser. The foaming component includes an air sparging element, a mixing chamber, and an air chamber. The mixing chamber is on one side of the air sparging element and it defines a portion of the mixing chamber. The air chamber is on the other side of the air sparging element and it defines a portion of the air chamber. The air chamber has an air inlet. The mixing chamber has a liquid inlet and an outlet, and the outlet is down stream of the inlet. The foaming component also forms part of a new foam dispenser. The foaming component and the foam dispenser are for use in the production of foam with a plurality of particles suspended therein.
Patent AU-2005280004-B2 (AU)
Title: Modified HIV-1 envelope proteins
Inventor: QUINNAN GERALD
IPC: A61K39/12
Filed: 2005-08-29
Granted: 2012-02-23
Abstract: The present invention relates to modified HIV-1 envelope proteins which express epitopes that produce a broadly cross reactive neutralizing response, their methods of use and antibodies which bind to these epitopes.
Patent AU-2005297570-B2 (AU)
Title: 3,6-substituted 5-arylamino-1H-pyridine-2-one derivatives and related compounds as poly(ADP-ribose)polymerase (PARP) inhibitors in the treatment of tissue damage or disease caused by necrosis or apoptosis
Inventor: HOFMEISTER ARMIN
IPC: A61P9/10
Filed: 2005-10-05
Granted: 2011-06-16
Abstract: This invention relates to compounds of formula (I), wherein R1 and R3 independently represent fluorine, methoxy, —OCF3, C2-C3-alkenyl or C1-C4-alkyl which is optionally substituted by chlorine, methoxy or one, two or three fluorine atoms; R2 represents hydrogen, fluorine, methoxy, —OCF3, C2-C3-alkenyl or C1-C4-alkyl which is optionally substituted by chlorine, methoxy or one, two or three fluorine atoms; X represents O, S, NH or N(C1-C3-alkyl); and Ar represents an unsubstituted or at least monosubstituted aryl or heteroaryl. Said compounds are inhibitors of poly(ADP-ribose) polymerase (PARP), and may be used for the treatment of a variety of disorders.