Patent GB-1036311-A (GB)
Title: Film-forming antimicrobial compositions containing organo-mercury compounds and the use thereof
IPC: C07F3/10
Filed: 1963-02-05
Abstract: A fungicidal water-resistant film-forming aerosol composition for use on the interior surfaces of tanks and vessels employed in paper manufacture, comprises 1-20% alkyl or aryl mercuric acrylate or methacrylate or mixture thereof, 5-20% volatile organic solvent and the residuum being volatile propellant. Specific mercury compounds mentioned are p-hydroxyphenyl, p-chlorophenyl, methyl, ethyl and cycloalkyl mercuric methacrylates, the cycloalkyl group having 4-9 C atoms.  Also disclosed are tolyl, xylyl, naphthyl, o- or pderivatives of hydroxy and chloro phenols, pyridyl, butyl, nonyl, lauryl, myristyl, palmityl, stearyl, cyclobutyl, cyclopentyl, cyclohexyl, cyclo-octyl and cyclononyl.  The preparation of these compounds is described (see Division C2).  Suitable solvents to make the composition are methanol, ethanol, propanol, isopropanol, butanol, acetone and dioxan.  Ethylene glycol monoethyl ether may also be added to the composition.  The propellant for the aerosol may be dichlorodifluoromethane, trichloromonofluoromethane, methylene chloride or mixtures thereof with or without a watermiscible solvent. To aid in the formation of a film an acrylic resin, e.g. " Acryloid B-72 ", or nitrocellulose may be incorporated.  The composition may be used to prevent microbal growth in starch suspensions, caesin solutions, animal glues and other proteinaceous material. It is stated that paper-making equipment treated with the composition are also rendered free of pulp build-up.ALSO:The invention comprises aryl and alkyl mercuric acrylates and methacrylates wherein the alkyl group has up to 18 C atoms. Specifically claimed are phenyl, p-hydroxyphenyl, p-chlorophenyl, methyl and ethyl mercuric methacrylates and cyclo-alkyl mercuric methacrylates wherein the cycloalkyl group contains 4-9 C atoms. Also disclosed as aryl, alkyl and cycloalkyl groups are tolyl, xylyl, naphthyl, o-or p-derivatives or mixtures thereof of hydroxy and chlorophenyls, pyridyl; butyl, nonyl, lauryl, myristyl, palmityl, stearyl; cyclobutyl, cyclopentyl, cyclohexyl, cyclo-octyl and cyclononyl. These compounds are made by adding the corresponding aryl, alkyl or cycloalkyl mercuric hydroxide derivative to acrylic or methacrylic acid in methanol or isopanol. Antimicrobial compositions (see Division A5) of these compounds are made by dissolving them in a volatile organic solvent which may include a water-miscible solvent.  A film-forming material may also be incorporated, e.g. an acrylic resin preferably "Acryloid B-72," or nitrocellulose. Examples of solvents which may be used are methanol, ethanol, propanol, isopropanol, butanol, acetone and dioxan. Ethylene glycol monoethyl ether may also be added to the composition. These various compositions may be used as an aerosol having a non-toxic propellant, e.g. dichlorodifluoromethane with/without trichloromonofluoromethane with/without methylene chloride with/without a water-miscible solvent.  Numerous specific compositions are disclosed, including mixtures of acrylate and methacrylate derivatives.ALSO:A fungicidal water-resistant film-forming composition comprises 1-20% alkyl or aryl mercuric acrylate or methacrylate or mixture thereof, 5-20% volatile organic solvent and the residuum being volatile propellant.  Specific mercury compounds mentioned are p-hydroxyphenyl, p-chlorophenyl, methyl, ethyl and cycloalkyl mercuric methacrylates, the cyclo alkyl group having 4-9 C atoms. Also disclosed are tolyl, xylyl, naphthyl, o or p derivatives of hydroxy and chloro phenols, pyridyl, butyl, nonyl, lawyl, myristyl, palmityl, stearyl, cyclobutyl, cyclopentyl, cyclohexyl, cyclo-octyl and cyclononyl.  The preparation of these compounds is described (see Division C2).  Suitable solvents to make the composition are methanol, ethanol, propanol, isopropanol, butanol, acetone and dioxan.  Ethylene glycol monoethyl ether may also be added to the composition.  The propellant for the aerosol may be dichlorodifluoromethane, trichloromonofluoromethane, methylene chloride or mixtures thereof with or without a water-mixible solvent. To aid in the formation of a film an acrylic resin e.g. "Acryloid B-72", or nitrocellulose may be incorporated.  The composition may be applied as a paint or an aerosol.  The composition may be used to prevent microbial growth in starch suspensions, caesin solutions, animal glues and other protein-aceous material.ALSO:A fungicidal water-resistant film-forming composition for use on the interior surfaces of tanks and vessels employed in paper manufacture-for example in the white water re-circulating system, or in chests or mixing boxes-comprises 1-20% alkyl or aryl mercuric acrylate or methacrylate or mixture thereof, 5-20% volatile organic solvent and the residuum being volatile propellant.  Specific mercury compounds mentioned are p-hydroxyphenyl, p-chlorophenyl, methyl, ethyl and cycloalkyl mercuric methacrylates, the cycle alkyl group having 4-9 C atoms. Also disclosed are tolyl, xylyl, naphthyl, o or p derivatives of hydroxy and chloro phenols, pyridyl, butyl, nonyl, lawyl, myristyl, palmityl, stearyl, cyclobutyl, cyclopentyl, cyclohexyl, cyclooctyl and cyclononyl.  The preparation of these compounds is described (see Division C2).  Suitable solvents to make the composition are methanol, ethanol, propanol, isopropanol, butanol, acetone and dioxan.  Ethylene glycol monoethyl ether may also be added to the composition.  The propellant for the aerosol may be dichlorodifluoromethane, trichloromonofluoromethane, methylene chloride or mixtures thereof with or without a water-mixible solvent. To aid in the formation of a film an acrylic resin e.g. "Acryloid B-72", or nitrocellulose may be incorporated.  The composition may be applied as a paint or an aerosol.  The composition may be used to prevent microbal growth in starch suspensions, casein solutions, animal glues and other proteinaceous material.  It is stated that paper-making equipment treated with the composition are also rendered free of pulp build-up.