baber/WOPTO huggingface dataset:
Patent CA-2327733-A1 (CA)
Title: Use of a hyperpolarized gas for mri detection of regional variations in oxygen uptake from the lungs
Inventor: HEIL WERNER
IPC: A61B5/055
Filed: 1999-04-09
Abstract: The invention provides a method of detecting regional variations in oxygen uptake from the lungs of an air-breathing animal subject, said method comprising administering into the lungs of said subject a diagnostically effective amount of a gaseous hyperpolarized magnetic resonance imaging agent, detecting the magnetic resonance signal from said agent in said lungs, determining the temporal variation in relaxation rate for said signal for at least one region of interest whitin said lungs, and from said variation generating a qualitative or quantitative value or image indicative of the oygen concentration in at least one region of interest, and if desired the time dependency of such concentration.
Patent CA-2329287-A1 (CA)
Title: Host interface for imaging arrays
Inventor: SUSKA MARK
IPC: H04N5/335
Filed: 2000-12-21
Abstract: An interface for receiving data from an image sensor having an imaging array and a clock generator and for transferring the data to a processor system is described. The interface comprises a memory for storing the imaging array data and the clocking signals at a rate determined by the clocking signals. In response to the quantity of data in the memory, a signal generator generates a signal for transmission to the processor system and a circuit controls the transfer of the data from the memory at a rate determined by the processor system. The memory may be a first-in first-out (FIFO) buffer or an addressable memory. The interface is preferably integrated on the same die as the image sensor. The signal generator may generate either an interrupt signal for transmission to the processor system or a bus request signal for transmission to a bus arbitration unit for the processor system.
Patent CA-2333032-A1 (CA)
Inventor: KIM BEONG-JO
IPC: H04J13/10
Filed: 2000-04-03
Abstract: A device for generating L addresses, which are smaller in number than 2mxNg virtual addresses, for reading data from an interleaver memory in which L da ta bits are stored, the device including : Ng PN generators each including m memories; an address generator for adding an offset value to the input data size to provide a virtual address having a size of a multiple of 2m, and generating addresses other than addresses corresponding to the offset value in address generation areas using the address generation areas having the size of 2m; and means for reading the input data from the interleaver memory using t he addresses generated from the address generation areas.
Patent CA-2333357-A1 (CA)
Title: Centrale electrique amelioree equipee d'un dispositif de capture du dioxyde de carbone
Inventor: URSIN TORD PETER
IPC: F23C9/08
Filed: 1999-06-02
Abstract: On décrit un procédé de production d'énergie à pollution réduite, qui consiste à brûler un combustible avec un apport d'oxygène très concentré dans une chambre de combustion (714) dans laquelle des produits de combustion recirculés sont introduits pour réguler la température. Le procédé se caractérise en ce que tout ou partie des produits de combustion sont refroidis (727) à une température appropriée qui empêche tout ou la majeure partie de la vapeur d'eau de se condenser à partir desdits produits, avant que ces produits ne soient comprimés et recirculés vers la chambre de combustion.
Patent CA-2335512-A1 (CA)
Inventor: LINDGREN GORAN
IPC: B24B41/06
Filed: 1999-06-23
Abstract: The present invention relates to a fixture and a grinding machine for grinding buttons of a rock drill bit. The fixture (18) comprises means (20, 25, 26) for holding the drill bit in a horizontal plane in a correct position relative to a grinding cup (51). The fixture comprises a linkage (24) consisting of at least two arms (25, 26). The arms (25, 26) are mutually joined by a first vertical hinge (27) wherein a second arm (26) is movably secured in a machine stand (23). A locking means (45) is provided to lock two arms (25, 26) simultaneously.  During use operative peripheries of the arms to be locked are held at a substantially constant distance from each other.
Patent CA-2337793-A1 (CA)
Inventor: KOBAYASHI HISASHI
IPC: C22B21/06
Filed: 1999-07-12
Abstract: A process for melting an aluminum charge into molten aluminum and simultaneously refining the molten aluminum to produce a refined molten aluminum having a low hydrogen content in a direct fired furnace (10) is provided.
Patent CA-2339604-A1 (CA)
Title: Raceway fitting with or without base fitting
Inventor: BATESON GARY W
IPC: H02G3/04
Filed: 2001-03-07
Abstract: A cover fitting for connecting more than one raceway includes an L-shaped top having first and second grooves extending along the inner surface of the top and a plurality of hooks extending outwardly from the inner surface for engaging a portion of each raceway base. The cover fitting further includes first and second opposing sides extending from the inner surface of the top. The cover fitting can be used with a fitting base received in first and second grooves for situations requiring a specific bend radius, or in applications without a fitting base, where there are no bend radius requirements.
Patent CA-2340259-A1 (CA)
Title: Treatment of fecal incontinence
Inventor: MCMICHAEL JOHN
IPC: A61P13/00
Filed: 1998-11-13
Abstract: The present invention relates to a treatment for patients having fecal incontinence by administering a composition comprising histamine, serotonin or a combination thereof in an amount effective to alleviate symptoms of fecal incontinence.
Patent CA-2341636-A1 (CA)
Inventor: HOOCK THOMAS
IPC: C07K19/00
Filed: 1999-08-31
Abstract: La présente invention concerne des molécules de fusion d'un type nouveau, des molécules d'ADN codant pour ces nouvelles molécules, des vecteurs renfermant ces molécules d'ADN et des cellules hôtes renfermant ces vecteurs pour la mesure de l'activité protéase au moyen d'une nouvelle analyse transcriptionnelle. L'invention concerne également un procédé destiné à déterminer l'activité inhibitrice d'un composé à l'égard d'une protéase et un autre procédé permettant de comparer l'activité de deux protéases qui reconnaissent le même site de coupure. L'invention s'intéresse également à des kits d'analyse de l'activité protéase avec molécules d'ADN codant pour les substrats des protéines de fusion selon l'invention.
Patent CA-2347591-A1 (CA)
Inventor: DAI YUZHONG
IPC: G02B6/024
Filed: 2001-05-15
Abstract: A packaged polarization maintaining fiber includes a cylindrical polarization maintaining fiber packaged with an elliptical packaging. The elliptical packaging includes solder securing the polarization maintaining fiber within a sleeve. The optical fast and slow axes of the polarization maintaining fiber may be aligned within the packaging to reduce the effects of eccentricity on the extinction ratio of the polarization maintaining fiber. A packaged polarization maintaining fiber is also provided having a circular cross-section. The packaging materials and dimensions may be chosen such that the stress at the interface between the polarization maintaining fiber cladding and the solder is zero, thereby reducing the chance of stress induced breakages in the fiber and reducing stress induced degradation of the extinction ratio of the polarization maintaining fiber.
Patent CA-2347680-A1 (CA)
Inventor: PIERROU JAMES R
IPC: F15B11/028
Filed: 1999-10-29
Abstract: Selon un mode de réalisation préféré, la présente invention concerne un manocontact hydraulique en communication fluidique avec la sortie d'une pompe hydraulique alimentant un appareil à plate-forme de levage. Ce manocontact est étalonné pour s'enclencher sous une pression de sortie déterminée de la pompe en cas de commande de rappel en position verticale de rangement de la plate-forme sous charge. A l'inverse, ce manocontact est étalonné pour ne pas s'enclencher sous une pression de sortie déterminée de la pompe en cas de commande de rappel en position verticale de rangement de la plate-forme à vide. L'actionnement du manocontact rend la pompe hydraulique inopérante, ce qui empêche de replier la plate-forme en position de rangement sous charge.
Patent CA-2351919-A1 (CA)
Title: Installation for hardening tubular concrete workpieces
Inventor: SCHLUSSELBAUER JOHANN
IPC: B28B21/92
Filed: 2001-06-27
Abstract: An installation is described for hardening tubular concrete workpieces (1) in chambers (2) which are open at the top, can be closed with cover plates (3) and can be subjected to vapour and which can be charged with the aid of an overhead travelling crane (6) bearing a hoist (9) for workpieces (1). In order to achieve an advantageous construction constellation it is recommended that the overhead travelling crane (6) for the workpieces (1) has a gripping device for the cover plates (3) of the chambers (2).
Patent CA-2354136-A1 (CA)
Title: Amplificateur optique a semi-conducteur
Inventor: ECKNER JURG A
IPC: H01S5/40
Filed: 1999-12-09
Abstract: L'invention porte sur un amplificateur optique à semi-conducteur comprenant un élément à semi-conducteur à plusieurs faces latérales planes, au moins un guide d'ondes présentant une entrée et une sortie communicant avec l'élément à semi-conducteur, une partie au moins du guide d'ondes étant faite d'un matériau semi-conducteur actif, et l'entrée et la sortie du guide d'ondes étant située sur la même surface latérale plane, ou sur deux surfaces latérales planes contigües.
Patent CA-2355084-A1 (CA)
Title: Microfluidic circuit designs for performing electrokinetic manipulations that reduce the number of voltage sources and fluid reservoirs
Inventor: RAMSEY J MICHAEL
IPC: G01N1/38
Filed: 1999-12-15
Abstract: A microfabricated device and method for proportioning and mixing electokinetically manipulated biological or chemical materials is disclosed.    The microfabricated device (5) mixes a plurality of materials in volumetric proportions controlled by the electrical resistances of tributary reagent channels (31a, 31b, 33a, 33b, 35a, 35b, 37a, 37b, 38a, 38b, 39a, 39b) through which the materials are transported. The microchip (5) includes two or more tributary reagent channels combining at one or more junctions (41, 42, 43, 44, 45) to form one or more mixing channels (36a, 36b, 36c, 36d, 36e). By varying the geometries of the channels (length, cross section, etc.), a plurality of reagent materials can be mixed at a junction such that the proportions of the reagent materials in the mixing channel depend on a ratio of the channel geometries and material properties. Such an approach facilitates voltage division on the microchip without relying on external wiring schemes and voltage division techniques external to the microchip. Microchannel designs that provide the necessary voltage division to accomplish electrokinetic valuing operations using a single voltage source and a switch are also described. In addition, microchannel designs that accomplish fluidic operation utilizing a minimal number of fluidic reservoirs are disclosed.
Patent CA-2355776-A1 (CA)
Title: Phospholipid complexes of proanthocyanidin a2 as antiatherosclerotic agents
Inventor: BOMBARDELLI EZIO
IPC: A61K47/48
Filed: 1999-12-13
Abstract: The phospholipid complexes of proanthocyanidin A2 are useful for the prevention and the treatment of pathological conditions on atherosclerotic base.
Patent CA-2356545-A1 (CA)
Title: Pharmaceutical combinations for the treatment of stroke and traumatic brain injury
Inventor: SALTARELLI MARIO DAVID
IPC: A61K31/453
Filed: 2001-09-04
Abstract: This invention relates to methods of treating traumatic brain injury (TBI) or hypoxic or ischemic stroke, comprising administering to a patient in need of such treatment an NR2B subtype selective N-methyl-D-aspartate (NMDA) receptor antagonist in combination with either: (a) a sodium channel antagonist; (b) a nitric oxide synthase (NOS) inhibitor; (c) a glycine site antagonist; (d) a potassium channel opener; (e) an AMPA/ kainate receptor antagonist; (f) a calcium channel antagonist; (g) a GABA-A receptor modulator (e.g., a GABA-A receptor agonist); or (h) an antiinflammatory agent. This invention also relates to methods of treating hypoxic or ischemic stroke comprising administering to a patient in need of such treatment an NMDA receptor antagonist in combination with a thrombolytic agent.
Patent CA-2357292-A1 (CA)
Inventor: HEFFNER STEVEN P
IPC: B61D19/00
Filed: 2001-09-13
Abstract: A mechanical power conversion device for receiving rotary power from a rotary power supply and delivering two independent power outputs, the conversion device having: a drive screw connectable to the rotary power supply, a drive nut engaging the drive screw to receive a drive nut axial force and drive nut torsion therefrom, the drive nut axial force being parallel to the drive screw and the drive nut torsion being about an axis of the drive screw. One of the two independent power outputs is connected to the drive nut to receive the drive nut axial force and the second is connected to the drive nut to receive the drive nut torsion so that power from the rotary power supply flows to either or both of the first independent power output and the second independent power output.
Patent CA-2358585-A1 (CA)
Title: Rechargeable battery for headlight and attaching structure thereof
Inventor: OKUDA YOJI
IPC: B62J11/19
Filed: 2001-10-09
Abstract: A rechargeable battery for a headlight that can be firmly attached to a bicycle in a variety of locations including a bottle holder, and an attaching structure for attaching the rechargeable battery to the bicycle are provided.  The rechargeable battery for the headlight attached to the bicycle includes a wire (6) to electrically connect the rechargeable battery (1) to the headlight (15), and a through hole (2, 3) to let through a belt (12, 13) for attaching the body of the rechargeable battery (1) to the bicycle.
Patent CA-2360160-A1 (CA)
Title: Compartmentalized storage container
Inventor: HENDERSON JACK V
IPC: B60J7/08
Filed: 2001-10-29
Abstract: A storage assembly is disclosed for a vehicle having an open bed defined by opposing sidewalls, a front wall and a rear tailgate. The storage assembly includes a tonneau cover that covers at least a portion of the open bed. The tonneau cover is movable between open and closed positions to provide selective access to the open bed. A plurality of brackets extend between the opposing sidewalls, the front wall and the rear tailgate. A storage bin is removably securable to the brackets. The storage bin creates a removable compartment within the open bed allowing items stored therein to be organized and removed as a group when desired.
Patent CA-2361672-A1 (CA)
Title: Method for determining the concentration of thrombin inhibitors
Inventor: NOWAK GOTZ
IPC: G01N21/64
Filed: 2000-01-28
Abstract: The invention relates to a method for determining the concentration of thrombin inhibitors in a non-turbid body fluid or a non-turbid extract from a body fluid. The body fluid is taken from a living organism and is separated,  if required, from the turbidities. An anticoagulative agent that does not affect the prothrombin/active meizothrombin or Mtdesfg1 conversion process, a chromogenic or fluorogenic substrate that can be cleaved by active meizothrombin or Mtdesfg1 and a substance that cleaves prothrombin into meizothrombin or Mtdesfg1, in addition to prothrombin (optionally) are added  to the non-turbid body fluid thus obtained. The mixture thus obtained undergoes time-based wavelength-selective light absorption or light emission  measurement. The amount of thrombin inhibitor contained in the body fluid is  determined by means of comparision with determined standard curves on the basis of a decrease in the absorption or emission of light.
Patent CA-2362914-A1 (CA)
Title: Use of substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections
Inventor: BRYANT MARTIN L
IPC: A61P31/20
Filed: 2000-02-14
Abstract: N-Substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds of Formula (I) are effective in treatment of hepatitis infections, including hepatitis B and hepatitis C. In treating hepatitis infections, the compounds of Formula (I) may be used alone, or in combination with another antiviral agent selected from among nucleosides, nucleotides, immunomodulators, immunostimulants or various combinations of such other agents.
Patent CA-2366055-A1 (CA)
Title: Method for validating/invalidating target(s) and pathways
Inventor: NYCE JONATHAN W
IPC: C12Q1/6883
Filed: 2000-03-02
Abstract: A method of determining the existence of a correlation between a function of  a disease or condition and a gene or mRNA encoding a target polypeptide suspected of being associated with a disease or condition, comprises obtaini ng oligonucleotides (oligos) consisting of up to about 15 % adenosine (A), preferably having no adenosine content, and which is anti-sense to a target selected from the group consisting of target genes and their corresponding mRNAs, genomic and mRNA flanking regions selected from the group consisting of 3' and 5' intron-exon borders and the juxta-section between coding and non- coding regions, and all mRNA segments encoding polypeptides associated with a pre-selected disease or condition; selecting amongst the oligos one that significantly inhibits or ablates expression of the polypeptide encoded by t he mRNA upon in vitro hybridization to the target mRNA; administering to a subject an amount of the selected oligo effective for in vivo hybridization to the target mRNA; and assessing a subject=s function that is associated with the disease or condition before and after administration of the oligo; where in a change in the function=s value greater than about 70 % indicates a positiv e correlation, between about 40 and about 70 % a possible correlation, and bel ow about 30 % alack of correlation. The present method preferably administers the oligos in situ where the target is located, e.g. into the subject=s respiration when validating targets associated with malignant and other pulmonary and respiratory functions, so that the agent has direct access to the lungs. Alternatively, such desAdenosine oligos may be delivered directly  to the CNS or other organs, tissues and organ systems, by means of known delivery formulations.
Patent CA-2367156-A1 (CA)
Title: Device for a tool spindle
Inventor: LIND BJORN
IPC: B23B31/30
Filed: 2000-02-16
Abstract: Arrangement for a tool spindle with a pulling rod (3) axially displaceable in the spindle axle (1) for firmly attaching a tool at the spindle of the tool whereby the end of the pulling rod (3) that is opposite to the tool is accommodated in a stationary unit (4), the rotating part (1, 3) is provided with a piston (11) movably displaceable in a cylinder chamber (13) arranged in the spindle axle (1), the pulling rod (3) has at least one first axial bore (12a) opening into the cylinder chamber on one side of the piston (11) and at least one second (12b) axial bore opening into the cylinder chamber on the other side of the piston (11), the stationary unit (4) is provided with an inlet (16) in communication with the first bore (12a) and an inlet (14) in communication with the second bore (12b). The bores (12a, 12b) can be put under pressure or respectively relieved of pressure via inlet (16, 14) from a fluid for displacing the piston (11) in one of the directions depending on the desired displacement of the piston (11) and thereby the pulling rod (3) from a releasing to an attaching position and back again. Gap sealings that separate the rotating part (1, 3) from the stationary unit (4) are arranged on either side of the respective inlet (14, 16) thereby forming a dynamic bearing during the rotation of the rotating part due to the leakage of the fluid through the gap sealings.
Patent CA-2367636-A1 (CA)
Title: Fusion proteins
Inventor: MCKERRACHER LISA
IPC: A61K47/48
Filed: 2002-01-15
Abstract: The Rho family GTPases regulates axon growth and regeneration. Inactivation of Rho with C3, a toxin from Clostridium botulinum, can stimulate regeneration and sprouting of injured axons. The present invention provides novel chimeric C3-like Rho antagonists.  These new antagonists are a significant improvement over C3 compounds because they are 3-4 orders of magnitude more potent to stimulate axon growth on inhibitory substrates than recombinant C3. The invention further provides evidence that these compounds promote repair when applied to the injured mammalian central nervous system.
Patent CA-2368195-A1 (CA)
Inventor: BERTRAM MICHAEL C
IPC: H04N7/16
Filed: 2000-03-30
Abstract: L'invention porte sur un procédé et un appareil permettant l'accès conditionnel à un contenu à la demande de durée variable en utilisant soit le cryptage en temps réel du contenu, soit le précryptage du contenu. Dans les deux cas, l'intégration des messages de décryptage et les autorisations d'impulsions sont comprises dans le flux d'informations précryptées.
Patent CA-2370257-A1 (CA)
Inventor: SOLUM JEFF
IPC: H04L12/28
Filed: 2000-04-14
Abstract: A method for controlling power consumption in a communication device is provided. The method includes powering down a receiver of the communication device for a selected period of time and, when the selected period of time expires, powering up the receiver to check for incoming data.
Patent CA-2376027-A1 (CA)
Inventor: ADAMS MICHAEL E
IPC: A01K77/00
Filed: 2000-06-29
Abstract: The present invention is a disengageable self-locking pivotal bracket device  (10) that can be used as a foldable, pivotal connecting element that can connect two members (12, 14), for example a fish net (62) and handle (60), o r two sections of a cane. The device includes an axial/fastener and disengageable locking element for pivotally and releaseably locking the devi ce (10) into and out of at least one extended, engaged position. The device (10 ) further includes a stop (52) which contacts one of the members to limit pivoting in a first direction.
Patent CA-2378219-A1 (CA)
Title: Die cast compressor housing for centrifugal compressors with a true volute shape
Inventor: ADEFF GEORGE A
IPC: F04D29/42
Filed: 2000-06-30
Abstract: A die cast compressor housing includes an outer shell (10) having a partial outer circumferencial volute wall (32) portion and a projection (34) surrounding the circumference of an aperture (30) in the shell (10) that mates with an insert (12) having a first portion with a substantially cylindrical outer wall that is received in the aperture (30) in the outer shell (10) and includes an air inlet. The insert (12) has a second portion extending radially outwardly and including a mating projection (28) for engagement with the outer shell projection (34) to form an inner circumferencial volute wall portion. A backplate (14) has a third projection (38) adjacent its outer circumference that is received in a relief (40) in the outer shell (10) and completes the outer circumferencial volute wall portion. The outer shell projection (34) has a first land (70) engaging a second land (72) on the mating projection, the first and second lands (70, 72) spirally descending relative to a datum (45) and the relief (40) has a third land (76) in spaced relation to a fourth land (74) on the third projection (38), the third and fourth lands (76, 74) spirally descending respectively relative to the datum (45).
Patent CA-2378763-A1 (CA)
Title: Tuberculosis vaccine and diagnostics based on the mycobacterium tuberculosis esat-6 gene family
Inventor: ANDERSEN PETER
IPC: A61K39/00
Filed: 2000-07-13
Abstract: This invention relates to a polypeptide fragment which comprises an amino acid sequence encoded by a member of the esat-6 gene. A member of the esat-6 gene family is defined as gene encoding a small protein and that two such genes are arranged next to each other on the genome and that at least one of the gene products has an amino acid sequence identity to either Rv3874, Rv3875, or Rv0288 of at least 15 %.