baber/WOPTO huggingface dataset:
Patent WO-9931240-A2 (WO)
Inventor: HERMEKING HEIKO
IPC: C07K14/47
Filed: 1998-12-18
Abstract: L'exposition d'un cancer colorectal (CRC) à un rayonnement ionisant entraîne un arrêt de la croissance, les cellules restant bloquées dans les phases G1 et G2 du cycle cellulaire. Il a été démontré que le blocage en G1 résulte de l'induction à médiation p53 de l'inhibiteur p21?WAF1/CIP1/SDI1¿ de kinase dépendant de la cycline, mais on ne connaît pas la cause du blocage en G2. A l'aide d'une analyse quantitative des motifs d'expression génique dans les lignées cellulaires du CRC, nous avons découvert que 14-3-3σ est fortement induit par le rayonnement η et d'autres agents endommageant l'ADN. L'induction de 14-3-3σ se produit sous la médiation d'un élément sensible à p-53 situé à 1,815 kb en amont de son site de début de transcription. L'introduction exogène de 14-3-3σ dans les cellules proliférantes provoque un blocage en G2 similaire à celui qui est observé à la suite d'une irradiation. Ces résultats démontrent un mécanisme moléculaire de blocage G2/M qui, dans les cellules humaines, est régulé par p53.
Patent WO-0029617-A2 (WO)
Inventor: NIE SHUMING
IPC: C12Q1/68
Filed: 1999-09-24
Abstract: L'invention concerne un point quantique luminescent soluble dans l'eau, son conjugué biomoléculaire et une composition comprenant ce point quantique ou ce conjugué. De plus, l'invention concerne un procédé d'obtention d'un point quantique luminescent, un procédé de préparation de son conjugué biomoléculaire et des procédés d'utilisation d'un conjugué biomoléculaire pour une détection nonisotopique ultrasensible in vitro et in vivo.
Patent WO-0020607-A2 (WO)
Title: Proteines chimeres parmi les membres de la superfamille du tgf-beta
Inventor: OPPERMANN HERMANN
IPC: C07K14/47
Filed: 1999-10-07
Abstract: La présente invention concerne des ADN et des protéines modifiées de la superfamille du TGF-β, notamment des protéines morphogéniques modifiées. Les protéines de cette invention présentent des attributs biologiques ou biochimiques modifiés. Plus particulièrement, ces protéines modifiées sont élaborées en substituant des amino-acides dans le sous-domaine du doigt 2, ou en échangeant le sous-domaine du doigt 2 d'un membre de la superfamille du TGF-β dans sa totalité ou en partie, par le sous-domaine du doigt 2 d'un autre membre de la superfamille des TGF-β.
Patent WO-0127961-A2 (WO)
Title: Phosphores cathodoluminescents enduits
Inventor: SANGHERA JASBINDER S
IPC: H01J31/12
Filed: 1999-08-24
Abstract: Cette invention concerne des particules de phosphore et des écrans à émission de champ utilisant lesdites particules. Les particules sont enduites d'un matériau électroconducteur qui leur confère une stabilité environnementale, une stabilité dans des conditions d'utilisation, et une charge réduite, lesquelles réduisent l'efficacité et la durée de vie des particules.
Patent AR-240874-A2 (AR)
IPC: A01N25/26
Filed: 1986-05-30
Abstract: UN METODO PARA PREPARACION DE UNA COMPOSICION QUE CONTIENE UN AGENTE BIOLOGICAMENTE ACTIVO DE LIBERACION PROLONGADA, CARACTERIZADO PORQUE COMPRENDE LOS PASOS DE: A) PREPARAR UNA EMULSION O DISPERSION ACUO SA DE UN AGENTE BIOLOGICAMENTE ACTIVO APROPIADO Y UNA CARGA OPTATIVA EN UN MATERIAL FORMADOR DE MATRIZ QUE COMPRENDE UNA SOLUCION O GEL ACUOSOS DE UN POLI-HIDROXI-POLIMERO (PHP), EN DONDE DICHA SOLUCION O GEL TIENE UNA CONCENTRACION DE SOLIDOS DE DICHO PHP DE 3 A 40 % Y EN DONDE LA CANTIDAD RELATIVA DE DICHO PHP CON RESPECTO A DICHO AGENTE BIOLOGICO ACTIVO ES SUFICIENTE PARA ATRAPAR A DICHO AGENTE DENTRO DE UNA MATRIZ DE DICHO PHP; B) MEZCLAR EN DICHA EMULSION-DISPERSION UNA SAL INORGANICA DURANTE UN TIEMPO SUFICIENTE PARA DISTRIBUIRLA EN TODA LA EMULSION ACUOSA, EN DONDE LA SAL COMPREDE 1-30% PONDERAL DEL PRODUCTO DEL PASO B; C) HACER REACCIONAR EL PRODUCTO DE B A UN PH ALCALINO CON ACIDO BORICO O A UN PH ESENCIALMENTE NEUTRO O ALCALINO CON UN DERIVADO DE ACIDO BORICO PARA FORMAR UNA FASE DE MATRIZ INSOLUBILIZADA QUE TIENE ATRAPADA EN LA MISMA SITIOS UNIFORMEMENTE DISPERSADOS, DISCONTINUOS DE AGENTE Y UNA FASE ACUOSA OPTATIVA QUE LOS SEPARA DE DICHA FASE DE MATRIZ, Y D) RECUPERAR PARTICULAS DE LIBRE FLUIDEZ DE DICHO AGENTE BIOLOGICAMENTE ACTIVO ATRAPADO.
Patent CH-706717-A2 (CH)
Title: Push rod for clock element i.e. diver watch, has spring that is arranged to bend and to act as valve spring if pressure reigning inside clock element i.e. diver watch, is higher than pressure reigning outside of clock element
Inventor: BRISWALTER SEBASTIEN
IPC: G04B3/04
Filed: 2012-07-09
Abstract: The rod (51) has a cylindrical reinforcement (50) inside which the push rod is laid out in a longitudinal manner. An elastic return spring (10) is arranged for the push rod, and another elastic return spring (13) is rolled up around a rod (8). The latter spring is placed after the former spring in a direction of an end of the rod. The latter spring is arranged to bend and to act as valve spring if pressure reigning inside a clock element i.e. diver watch, is higher than pressure reigning outside of the clock element. A cylindrical spacer (12) is arranged on the rod.
Patent CH-704246-A2 (CH)
Title: Micromechanical part for timepiece, has balance including body forming flywheel, pin in integral and projection with body, and hairspring formed with assembly of balance and pin in integral manner
Inventor: CUSIN PIERRE
IPC: G04B17/06
Filed: 2010-12-21
Abstract: The part (1) has a balance (3) including a body (2) forming a flywheel, where the part is made of metal, metal alloy or silicon-based material. A pin (9) is in integral and projection with the body. A hairspring (7) is formed with an assembly of the balance and the pin in an integral manner. The balance is mounted on a staff (5), so as to be mounted in rotation between a bridge and a plate by a clock movement. The hairspring includes a spiral spring (12) integrally formed with a collet (14), which is adjusted on the staff. An independent claim is also included for a method for manufacturing a micromechanical part.
Patent CH-707382-A2 (CH)
Inventor: OERTLI CHRISTIAN
IPC: B01L3/00
Filed: 2012-12-21
Abstract: Der aus einem durchsichtigen Material geformte Probenbehälter (1) für eine zu testende Flüssigkeit hat Anzeigemittel (16) für mindestens eine Eigenschaft der Flüssigkeit, die an einem in ihm eingeschlossenen Anzeigeträger (10) befestigt sind, so dass die Anzeigemittel (16) durch die durchsichtige Umfangswand (2) des Probenbehälters (1) hindurch ablesbar sind.
Patent CO-6290652-A2 (CO)
Title: Proceso para la preparcion de sulfamatos de heteroarilo benzofusionado y la forma cristalina de n-(((2s)-6-cloro-2,3-dihidro-1,4benzodioxin-2il)metil-sulfamida
Inventor: ABDEL-MAGID AHMED
IPC: C07D311/58
Filed: 2010-09-27
Abstract: La presente invención se dirige a un proceso para la preparación de sulfamatos de heteroarilo benzofusionado, útiles para el tratamiento de epilepsia y trastornos relacionados, de conformidad con la Fórmula (lA) y con un compuesto cristalino de la Fórmula (l-S). Proceso para la preparación de un compuesto de Fórmula (lA).
Patent CO-6551703-A2 (CO)
Title: Aplicador de tapón activado con jalado
Inventor: WINKEL PAULA CARDINAHL
IPC: A61F13/20
Filed: 2012-05-23
Abstract: Un aplicador activado con jalado incluye un barril, un tapón una agarradera para de dedo y un elemento de desplegado. El tapón incluye una cuerda de retiro y esta localizado dentro del barril. El barril, el tapón y el elemento de desplegado están configurados de manera que la aplicación de una fuerza al elemento de desplegado en una primera dirección despliega el tapón y la cuerda de retiro desde el barril en una segunda dirección generalmente opuesta a la primera dirección.
Patent DD-217193-A2 (DD)
Title: Polyelektrolytisches flockungsmittel zur beschleunigung der feststoffsedimentation aus kohlehaltigen abwaessern
Inventor: SCHOENHERR DIETER
IPC: C02F1/52
Filed: 1983-07-13
Abstract: Es soll die Wirtschaftlichkeit des Flockungsvorganges fuer braunkohlenhaltige Abwaesser verbessert, die Absetzzeit verkuerzt und die Reinheit des Klarwassers erhoeht werden. Fuer die Ausflockung der Kohlesubstanz aus insbesondere braunkohlenhaltigen Abwaessern soll ein geeignetes Flockungsmittel mit unterschiedlicher Ionogenitaet der Komponenten gefunden werden. Das wird dadurch erreicht, dass den braunkohlenhaltigen Abwaessern mit Feststoffkonzentrationen von 5 bis 10 g/l eine 0,1%ige waessrige Loesung nicht ausschliesslich von kationischem hochmolekularem Poly(dimethyl-diallyl-ammoniumchlorid), gemaess WP 203 305 sondern zu gleichen Teilen von nichtionischem oder anionischem Polyacrylamid-Polymer in einem Mengenbereich von insgesamt 0,25 bis 4 ml/l Abwasser zugegeben wird.
Patent EP-1091556-A2 (EP)
Inventor: SAITO KYOJI
IPC: G06F13/00
Filed: 2000-05-26
Abstract: A plurality of destination mail addresses for
broadcast transmission input from a panel control
section (18) is temporarily stored in an address data
buffer (403). An address reading control section (407)
reads the destination mail addresses from the address
data buffer(403) in order to divide the plurality of
destination mail addresses to a plurality of groups in
unit of setting value M. A mail creating section (408)
creates e-mail directing to a destination mail address
belonging to each group. This makes it possible to limit
the number of destination mail addresses, which is input
to a destination filed [To:] of one e-mail, to the setting
value M. Also, this makes it possible to prevent a header
portion from being needlessly increased at the time of
broadcast transmission.
Patent EP-1074205-A2 (EP)
Inventor: MAINETTI MARIO
IPC: A47G25/30
Filed: 2000-06-30
Abstract: The clothes hanger for garments having a shaped shoulder has
the two ends (2) constituted by two surfaces which are essentially
planar.
Patent EP-1070659-A2 (EP)
Inventor: VIGNOCCHI LORIS
IPC: B62K25/08
Filed: 2000-07-17
Abstract: The pieces to be reciprocally connected are mechanically manufactured with
tolerances such that the outer diameter of the ends of the tubes (6, 6 ) is suitably
greater than the inner diameter of the seats of the ends of the crowns (1). The
crowns are heated to a temperature which does not cause a permanent deformation
in the pieces and which is such as to slightly increase the diameter of their seats. The
tubes instead are inserted by their ends to be connected, in a liquid nitrogen bath that
suitably restricts the outer diameter of said ends and brings them substantially to a
condition of equality or inferiority with respect to the diameter of the dilated seats of
the ends of the crowns. The cooled ends of the tubes are then inserted into the
heated end of the seats of the crowns and when the pieces return to room
temperature, they are connected with the predetermined tightness.
Patent EP-1087131-A2 (EP)
Inventor: BANZHAF WERNER
IPC: F02M59/46
Filed: 2000-09-20
Abstract: The solenoid valve (5) has a fuel feed conduit (7),
and a shutter in the form of a ball (12) controlled by an
electromagnet (14) and cooperating with a conical seat
(13) in the conduit (7). The conduit has a fuel filter
(18, 19) for preventing particles of dirt from getting
between the seat (13) and the shutter (12), without
causing an excessive fall in fuel pressure. The filter
(18, 19) is defined by a metal plate (18) having a number
of holes (19) of about 0.1 mm in diameter and formed
using laser technology; and the plate (18) is fitted to
the opposite end (21) of the conduit (7) from the seat
(13).
Patent EP-1004819-A2 (EP)
Inventor: KEIJI KASHIMA
IPC: F21V8/00
Filed: 1995-02-28
Abstract: A linear light source is disposed adjacent to the side
face of a transparent light conducting plate. The thickness of
the light conducting plate decreases as the position goes away
from the light source. Light diffusing elements are formed on
the major surface of the light conducting plate opposite to its
light exit surface. At least one transparent sheet has, on the
same surface thereof, a number of prisms having straight ridges
that are arranged substantially parallel with each other at
small intervals. The transparent sheet is disposed on the side
of the light exit surface of the light conducting plate so that
extensions of the straight ridges intersect the light source
substantially perpendicularly.
Patent EP-1083764-A2 (EP)
Inventor: YONEYAMA TOKUJI
IPC: H04M1/67
Filed: 2000-09-07
Abstract: Portable wireless communication terminals such as
cellular phones are equipped with features that are useful
in controlling an operational mode in response to
termination attempts according to a predetermined set of
rules. When the rules are satisfied, the mode switch process
in the remote cellular phone is able to change its
operational mode without establishing a line connection.
In addition, the remote cellular phone is also able to
display a predetermined message such as contact information
that is helpful in returning a lost cellular phone to an
owner.
Patent EP-1023828-A2 (EP)
Inventor: HORNE JOHN HENRY
IPC: A01K1/03
Filed: 2000-01-21
Abstract: To protect wildlife, such as wild birds, from predators, such as
kestrels, cats and squirrels, a mesh enclosure (10) is provided.
it is important that two sizes of mesh aperture (14, 16) are
provided. These may permit access to two different species or
groups of species of different size. Alternatively, particularly
in the case of enclosures to surround nesting boxes, the smaller
apertures may not allow access, and the larger ones allow access
only to one or two selected species. Such an enclosure may also
be used underwater for aquatic creatures.
Patent EP-1069464-A2 (EP)
Inventor: NORITAKE KAZUTO
IPC: G02F1/1362
Filed: 2000-07-12
Abstract: An insulator substrate (10) is provided with a TFT including
a first gate electrode (11), a gate insulating film (12), a
semiconductor film (13) disposed above the first gate electrode
(11), and an interlayer insulating film (15). On the interlayer
insulating film (15) in a position above a channel (13c), the TFT
further includes a second gate electrode (17) connected to the first
gate electrode (11). A reflective display electrode (20) composed
of a reflective material and connected to a source (13s) of the
TFT is arranged to extend over the TFT. In addition, the gap (37)
between adjacent reflective display electrodes (20) is arranged
in a position other than a position above a drain signal line (52).
With this arrangement, even when a black image is displayed on a
crystal display device of a normally white mode, display defects
due to reflection of incident light by a signal line are prevented.
Furthermore, a reflection type liquid crystal display device
having a high aperture rate and minimal fluctuation in the TFT
characteristics can be achieved.
Patent EP-1081992-A2 (EP)
Inventor: NAKAGAWA TATSUYA
IPC: H05K1/02
Filed: 2000-08-31
Abstract: A component mounting circuit board includes a circuit
pattern (80) including a plurality of electrically conductive
plates (3, 4, 5, 15, 16, 17, 29, 30, 33, 34, 38, 39), an inner
electrical component (49, 50, 51, 52, 59, 60, 61, 62) electrically
connected to the circuit pattern (80), and a resin molded section
(2) made of a resin by way of molding so as to cover the circuit
pattern (80) and the inner electrical component (49, 50, 51, 52,
59, 60, 61, 62). The resin molded section (2) has an opening
(9, 10, 11) allowing an outer electrical component (46, 47, 54,
56, 63, 65) located outside the resin molded section (2) to be
connected to the circuit pattern (80) through it.
Patent EP-1154473-A2 (EP)
Inventor: SAKAMOTO NORIAKI
IPC: H01L23/50
Filed: 2000-10-03
Abstract: In the present invention there is formed a sheet-like board
member 50 having conductive coating films, such as first pads
55 and die pads 59, formed thereon or a sheet-like board member
50 which has been half-etched by using conductive coating
films such as first pads 55 and die pads 59. A hybrid IC can
be manufactured by means of utilization of post-processing
processes of a semiconductor manufacturer. Further, a hybrid
IC can be manufactured without adoption of a support board,
and hence there can be manufactured a hybrid IC which is of
lower profile and has superior heat dissipation
characteristics.
Patent EP-1158891-A2 (EP)
Inventor: KIENZLE THOMAS C III
IPC: A61B19/08
Filed: 2000-02-10
Abstract: The patient is placed on a standard surgical table (102) so as to provide access to the body part (101) to be operated upon. A mobile fluoroscopic x-ray imaging device (110) with a flat panel x-ray imagery (114) is used to obtain multiple images of the patient's bony anatomy (101). A molbile fluoroscopic x-ray imaging device (110) with a flat panel x-ray imagery (114) is used to obtain mutiple images of the patient's bony anatomy (101). The images ar e then supplied to the system controller (121). A surgical tool (128) containing a plurality of localizing emitters (129) is used in the performance of the surgical procedure. A system controller (121) then displays on the system monitor (122) the images of the patient's anatomy superimposed with representations of the surgical tool (128).
Patent EP-1198243-A2 (EP)
Inventor: COHEN JOSEPH
IPC: A61K39/39
Filed: 2000-06-23
Abstract: La présente invention concerne une formulation de vaccin destinée à prévenir ou à soulager les infections à Plasmodium chez les humains.  Le vaccin de l'invention comprend un antigène de la malaria, en particulier une protéine qui comprend une partie de la protéine CS de P. falciparum fusionnée en phase via une séquence de liaison linéaire à l'extrémité N-terminale de HbsAg, et un oligonucléotide CpG immunostimulant.  L'invention se rapporte également à des procédés de fabrication de la formulation de vaccin de l'invention.  On peut également traiter les patients en leur administrant l'oligonucléotide CpG avant de leur administrer l'antigène de la malaria.
Patent EP-1196022-A2 (EP)
Inventor: SHINNERS KEVIN J
IPC: A01D43/08
Filed: 2000-06-30
Abstract: Yield monitor apparatus and method for a forage processing machinery are provided according to the invention. The yield monitor measures a forage yield by measuring a forage volume increment accumulation. In one embodiment of the invention, the yield monitor includes a volume increment accumulation measuring device generating a volume increment accumulation signal substantially related to a forage mass and a computer that receives the volume increment accumulation signal. The computer generates a yield amount based upon the accumulation signal, a forage processing machinery groundspeed, and forage processing machinery intake parameters. The yield monitor may generate a yield amount, with the yield amount capable of being stored and displayed to a forage processing machinery operator. Alternatively, the yield monitor may generate a groundspeed control signal that is used by the forage processing machinery to control a forage processing machinery groundspeed or other forage processing machinery parameters.
Patent EP-1203338-A2 (EP)
Title: Magnetkarte
Inventor: AHRENS HANS-JOACHIM
IPC: G06K19/04
Filed: 2000-08-09
Abstract: Die Erfindung betrifft eine einem Kundenkonto zuordenbare Magnetkarte, wobei die Magnetkarte im wesentlichen aus einem unzerbrechlichen, gummiartigen Material gebildet ist und wenigstens einen Magnetstreifen (12) aufweist.
Patent EP-1210463-A2 (EP)
Inventor: WOJNOWSKI LESZEK
IPC: C12Q1/6883
Filed: 2000-09-01
Abstract: Described are general means and methods of diagnosing and treating the phenotypic spectrum as well as the overlapping clinical characteristics with several forms of inherited abnormal expression and/or function of the CYP3A4, CYP3A7 and hPXR genes. In particular, polynucleotides of molecular variant CYP3A4, CYP3A7 and hPXR genes which, for example, are associated with insufficient metabolization and/or sensitivety of drugs, and vectors comprising such polynucleotides are provided. Furthermore, host cells comprising such polynucleotides or vectors and their use for the production of variant CYP3A4, CYP3A7 and hPXR proteins are described. In addition, variant CYP3A4, CYP3A7 and hPXR proteins and antibodies specifically recognizing such proteins as well as transgenic non-human animals comprising the above-described polynucleotide or vectors are provided. Described are also methods for identifying and obtaining inhibitors for therapy of disorders related to the malfunction of the CYP3A4, CYP3A7 and hPXR genes as well as methods of diagnosing the status of such disorders. Pharmaceutical and diagnostic compositions comprising the above-described polynucleotides, vectors, proteins, antibodies and inhibitors by the above-described method are provided. Said compositions are particularly useful for diagnosing and treating various diseases with drugs that are substrates, inhibitors or modulators of the CYP3A4, CYP3A7 or hPXR gene product.
Patent EP-1244705-A2 (EP)
Inventor: AFAR DANIEL E H
IPC: C12N1/15
Filed: 2000-12-06
Abstract: Described is a novel family of cell surface serpentine transmembrane antigens. Two of the proteins in this family are exclusively or predominantly expressed in the prostate, as well as in prostate cancer, and thus members of this family have been termed "STEAP" ( S ix  T ransmembrane  E pithelial  A ntigen of the  P rostrate). Four particular human STEAPs are described and characterized herein. The human STEAPs exhibit high degree of structural conservation among them but show no significant structural homology to any known human proteins. The prototype member of the STEAP family, STEAP-1, appears to be a type IIIa membrane protein expressed predominantly in prostate cells in normal human tissues. Structurally, STEAP-1 is a 339 amino acid protein characterized by a molecular topology of six transmembrane domains and intracellular N- and C-termini, suggesting that it folds in a "serpentine" manner into three extracellular and two intracellular loops. STEAP-1 protein expression is maintained at high levels across various stages of prostate cancer. Moreover, STEAP-1 is highly over-expressed in certain other human cancers.
Patent EP-1179096-A2 (EP)
Inventor: OLRY PIERRE
IPC: D03D15/12
Filed: 2000-12-05
Abstract: The carbonization of cellulose fiber fabric comprises an initial stage of heat treatment up to 250° C. to 350° C., with a relatively high mean temperature rise speed of 10° C./min to 60° C./min, an intermediate stage up to 350° C. to 500° C. with a lower mean temperature rise speed of 2° C./min to 10° C./min, and a final stage up to 500° C. to 750° C. with a mean temperature rise speed that is again raised to 5° C./min to 40° C./min.
Patent EP-1127748-A2 (EP)
Inventor: KYNAST ANDREAS
IPC: G10L15/00
Filed: 2001-01-30
Abstract: The speech control device has at least one microphone for input of speech signals and at least one loudspeaker for delivery of spoken messages, with a processor controlling an image display device in accordance with the spoken message, for providing a corresponding visual representation. An Independent claim for a speech control method is also included.
Patent EP-1139633-A2 (EP)
Inventor: KAZUYUKI YAMAGUCHI
IPC: H04W4/00
Filed: 2001-04-02
Abstract: To receive content services from a content server (24)
accepted in an Internet (22) via a GW (Gateway) unit (23 1 , 23 2 )
by a mobile user terminal (20) connected to a mobile communication
network (21), a plurality of GW units (23 1 , 23 2 ) are located in
respective predetermined areas. A part of radio communication
base stations (25 1 , 25 2 , ..., 25 N-3 , 25 N-2 , 25 N-1,  25 N ) to be the mobile
communication network (21) connects an access request to the
content server (24) accepted in the Internet (22) with a
predetermined GW unit (23 1 ). When the mobile user terminal (20)
moves from a first area to a second area (a movement (26)), roaming
service is executed among the radio communication base stations
(25 1 , 26 2 , ..., 25 N-3 , 25 N-2 , 25 N-1,  25 N ) in the mobile communication
network (21), the mobile user terminal (20) is connected to a
second GW unit (23 2 ), an inquiry is issued to another GW unit (23 1 ),
roaming service is executed among GW units (23 1 , 23 2 ), and thereby
content services are continued for the moving mobile user terminal
(20).