Patent GB-436327-A (GB)
Title: Improvements in or relating to the manufacture of insecticidal and fungicidal compositions
Filed: 1933-12-29
Abstract: Lauryl compounds stated to have insecticidal and fungicidal properties may be prepared as follows:--lauryl cyanate by heating lauryl bromide with potassium cyanate; lauryl urea by treating lauryl-amine with phosgene in toluene to give the urea chloride which is then caused to react with aqueous ammonia; lauryl thiourea similarly from lauryl - amine and thiophosgene; dilauryldithiocarbamates from laurylamine, carbon disulphide and alkali; lauryldiethyldithiocarbamate from potassium diethyldithiocarbamate and lauryl bromide; lauryl xanthate from carbon disulphide and potassium lauryloxide; and trilaurylamine by the action of laurylamine and lauryl bromide.  Reference has been directed by the Comptroller to Specifications 316,132, [Class 2 (iii)], and 393,276.ALSO:Insecticides and fungicides comprise as the active ingredient a lauryl derivative of the general formula C12H25.X, where X stands for halogen, OR or SR, (R being hydrogen or an organic radical), CN, CNO, or an amino or substituted amino group in which the nitrogen of the substituted amino group does not form part of a heterocyclic ring.  Examples of suitable lauryl derivatives are: lauryl alcohol and its ethers and organic esters, lauryl mercaptan and its thioethers, lauryl cyanide, lauryl cyanate, laurylamine, lauryl urea, lauryl thiourea, dilauryldithiocarbamates, trilaurylamine, lauryl bromide, lauryl xanthate, and lauryl diethyldithiocarbamate.  Crude lauryl alcohol obtained by the hydrogenation of coconut oil or its free fatty acids, and derivatives of this crude alcohol, may be used. Insoluble derivatives may be used as emulsions in water with or without an emulsifying agent and preferably with a spreader or wetting agent such as sulphonated fish oil or potash fish oil, or the lauryl derivatives may be added to a petroleum hydrocarbon such as kerosene.  Lauryl alcohol may be used in admixture with o-cresol as in the active ingredient. Specification 431,064 is referred to.  Lauryl cyanate may be prepared by heating lauryl bromode with potassium cyanate; lauryl urea by treating laurylamine with phosgene in toluene to give the urea chloride which is then caused to react with aqueous ammonia; lauryl thiourea similarly from laurylamine and thiophosgene; dilauryldithiocarbamates from laurylamine, carbon disulphide and alkali; lauryldiethyldithiocarbamate from potassium diethyldithiocarbamate and lauryl bromode; lauryl xanthate from carbon disulphide and potassium lauryloxide; and trilaurylamine by the action of laurylamine and lauryl bromide.  The Specification as open to inspection under Sect. 91 refers also to the use as parasiticides of all compounds in which X in the general formula given above consists of or comprises nitrogen, phosphorous, oxygen, sulphur, selenium, tellurium or a halogen, and refers particularly to esters of lauryl alcohol with inorganic acids; to esters with di- or polybasic acids which may be neutral esters or partial esters in which the remaining acid group is used for obtaining water solubility, such as sodium lauryl sulphate, sodium dilauryl phosphate, sodium lauryl xanthate, sodium lauryl mercaptan, and sodium lauryl phthalate; to the sulphur, selenium and tellurium analogues of lauryl ethers; to lauryl chloride, fluoride, sulphate, nitrate, phosphate, sulphonate, formate, chloracetate, benzoate and phthalate; to lauryl guanidine; and to lauryl derivatives in which the lauryl chain carries a negative constituent such as Cl or SO3H. The use of sulphonated animal, vegetable or mineral oils and of alkylated hydrocarbon sulphonic acids as emulsifying agents and of inert fillers such as diatomaceous earth is also referred to.  This subject-matter does not appear in the Specification as accepted. Reference has been directed by the Comptroller to Specifications 316,132, [Class 2 (iii)], and 393,276.