baber/WOPTO huggingface dataset:
Patent DE-69331792-T2 (DE)
Inventor: KAMIHARA SHINJI
IPC: C07D401/12
Filed: 1993-06-18
Granted: 2004-11-04
Abstract: A process for preparing a 2-(1-pyrrolidinyl)acetamide derivative useful as a cerebral function improving agent is disclosed, comprising reacting a halogenoacetamide derivative with substituted or unsubstituted 2-pyrrolidinone, the halogenoacetamide derivative being prepared by reacting an amine and a halogenoacetyl chloride. High yields of the intermediate compound as well as the final product are attained at low cost.
Patent DE-69404632-T2 (DE)
Inventor: BUTLER Donald
IPC: A61K31/40
Filed: 1994-02-24
Granted: 1998-01-29
Abstract: An improved process for the preparation of trans-6-(2-(substituted-pyrrole-1-yl)alkyl)pyran-2-ones by a novel synthesis is described where (alpha)-metalated N,N-disubstituted acetamide is converted in seven operations to the desired products, and specifically, a process for preparing (2R-trans)-5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1H-pyrrole-3-carboxamide, as well as other valuable intermediates used in the processes and prodrugs which are bioconverted to hypolipidemic and hypocholesterolemic agents and pharmaceutical compositions of the same.
Patent DE-69408837-T2 (DE)
Inventor: KAPEC JEFFREY
IPC: A61F2/00
Filed: 1994-04-06
Granted: 1998-06-25
Abstract: Methods and apparatus are set forth for preparing and delivering bone cement from a powdered polymer component and a liquid monomer component by simultaneously injecting the powdered and liquid components, stored in separate component chambers, into an evacuated mixing chamber under the effect of the vacuum; by uniformly mixing the components in the mixing chamber (to thoroughly wet the powder); and by delivering the cement formed by the polymerization process, as needed in an operative setting, utilizing a single ready to use device. The uniform mix is achieved by simultaneously subjecting the contents of the component chambers to the effects of the mixing chamber's vacuum via separate one way nozzles, interconnecting the component chambers to the mixing chamber, which cause the powder to be broadcast and liquid to be sprayed into the mixing chamber. The nozzles are designed and oriented in a predetermined manner (depending on the type and quantity of the constituent bone cement components being mixed), to cause the components to interact at a preselected distance within the mixing chamber, to assure uniform powder saturation and a thorough mix which yields a homogeneous reaction product.
Patent DE-69413229-T2 (DE)
Inventor: BOSLEY JOHN
IPC: H01L37/02
Filed: 1994-06-21
Granted: 1999-01-28
Abstract: PCT No. PCT/EP94/02060 Sec. 371 Date Apr. 8, 1996 Sec. 102(e) Date Apr. 8, 1996 PCT Filed Jun. 21, 1994 PCT Pub. No. WO95/01450 PCT Pub. Date Jan. 12, 1995Esters in which the alcohol part is sterically hindered around the ester bond, i.e. derived from tertiary alcohols are enzymatically prepared under low water conditions using Candida antarctica lipase A or a lipase species having a substrate activity similar to that of Candida antarctica lipase A with respect to tertiary alcohol esters.
Patent DE-69417868-T2 (DE)
Inventor: DUSSOURD D HINTERLAND LUCIEN
IPC: A61Q19/00
Filed: 1994-09-22
Granted: 2000-05-31
Abstract: PCT No. PCT/FR94/01108 Sec. 371 Date May 22, 1995 Sec. 102(e) Date May 22, 1995 PCT Filed Sep. 22, 1994 PCT Pub. No. WO95/08564 PCT Pub. Date May 30, 1995Provided is a compound containing a peptide of at least 4 amino acids including the following sequence: His Phe* Arg, wherein Phe* represents phenylalanine or a halogenated derivative of phenylalanine the said peptide being conjugated with thioctic acid, dihydrolioic acid, or N-lipoyl-lysine, in the form of the corresponding salts, esters or amides. In particular, compounds with anti-allergic and anti-inflammatory activities on the one had, and melanogenesis-activating activities on the other, are described.
Patent DE-69418994-T2 (DE)
Inventor: MIYAKAWA HARUMITSU
IPC: G10L19/00
Filed: 1994-11-25
Granted: 1999-12-02
Abstract: There is provided an encoding and decoding apparatus which can provide a high quality reproduction sound. There are provided an encoding section (1, 2, 3, 4, and 5) and a decoding section (7, 8, and 9) . A block length determining section (1) of the encoding section time-sharingly divides an input signal into blocks having a block length corresponding to the degree of change of the input signal. A frequency band dividing section (2) divides the signal of each block into a plurality of frequency bands. A bit allocating section (3) obtains a masking threshold value-to-noise ratio of each frequency band from the magnitude of the power of each frequency band reflecting a psychoacoustic characteristic, and determines the amount of quantization bits to be allocated to each frequency band based on the magnitude of the masking threshold value-to-noise ratio. A quantizing section (4) generates a code string by quantizing the signal while allocating a specified amount of bits to each frequency band based on information from the bit allocating section (3). The bit allocating section (3) receives information representing the block length from the block length determining section (1), and adopts a varied psychoacoustic characteristic according to the block length. <IMAGE>
Patent DE-69422726-T2 (DE)
Inventor: MONTANA JOHN
IPC: A61P7/04
Filed: 1994-11-10
Granted: 2000-06-08
Abstract: The present invention concerns novel mercaptoalkylpeptidyl compounds of formula (I) which are useful inhibitors of matrix metalloproteinase and/or TNF-mediated diseases including degenerative diseases and certain cancers. The invention also concerns methods of treating patients suffering from disorders or diseases which can be attributed to or are associated with matrix metalloproteinase or TNF activity.
Patent DE-69422848-T2 (DE)
Inventor: BATTARD JEAN-CLAUDE
IPC: A24B15/28
Filed: 1994-04-26
Granted: 2000-11-02
Abstract: Smoking article (cigar or cigarette) containing at least one smoking material chosen from among natural tobacco, reconstituted tobacco and tobacco substitutes comprising natural or synthetic non-tobacco products intended completely or partially to replace tobacco in a smoking article. For this purpose, the wrapper of the article has added to it a mixture of at least one reducing sugar which is non-volatile at room temperature and of at least one nitrogen-containing compound which releases ammonia at the temperature of and throughout the burning of the product.
Patent DE-69425005-T2 (DE)
Inventor: VAN DEN BRINK ROBERTUS FRANCIS
IPC: H04B10/43
Filed: 1994-01-28
Granted: 2001-03-08
Abstract: Known optical noise sources are equipped with a light source and an interference filter, optically coupled thereto and based on path length difference, for generating an optical composition signal. If the spectrum of a photodiode to be illuminated with the optical composition signal is to be as flat as possible, said path length difference must be considerably greater than the coherence length of the light source which in present practice leads to disadvantageously large path length differences. By feeding, according to the invention, a noise signal to the light source, the coherence length of the light source decreases, as a result of which it is sufficient to use considerably smaller path length differences. <IMAGE>
Patent DE-69425030-T2 (DE)
Inventor: NISHIBAYASHI YOSHIKI
IPC: C30B29/04
Filed: 1994-09-21
Granted: 2001-03-22
Abstract: A semiconductor device has a structure in which doped layers and undoped layers are alternately stacked and is constituted by (a) a semi-insulating substrate, (b) undoped layers consisting of a substantially undoped diamond material, and (c) thin doped layers formed between the undoped layers and consisting of a diamond material doped with B as an impurity. Stable operation characteristics can be obtained within a temperature range from room temperature to a high temperature while a semiconductor material having a deep impurity level is used. <IMAGE>
Patent DE-69430262-T2 (DE)
Inventor: LIU ZHIWEI
IPC: E04B1/343
Filed: 1994-12-23
Granted: 2002-11-07
Abstract: A structural frame of arch is formed with a plurality of curved frame units in parallel arrangement, said curved frame units having butt joints (6) are connected in length by several straight bars (16) and the butt joint (6), said straight bars are connected in line at right angles with the curved frame units in order to form a truss, said curved frame units comprise curved bars (14) and tie members (11) and said curved bars are connected to form the curved frame units by the tie members (11) and the butt joints (6), the tension member (9) is provided between the curved frame units and the trusses. <IMAGE>
Patent DE-69431180-T2 (DE)
Inventor: DELBARE WIM JOZEF ROBERT
IPC: G02B6/38
Filed: 1994-05-18
Granted: 2003-04-10
Abstract: The coupling structure is intended for coupling an optical termination (T1/T5) of an optical fiber conductor (F1/F5) to an optical terminal (T1'/T5') of an optical device which can be another optical fiber conductor. The structure includes a carrier (S, P) wherein the optical fiber conductor is so embedded that it has at least one locally bent portion reaching an outer surface of the carrier and forming there the optical termination. The carrier includes a first positioning means (P) to correctly position the optical termination with respect to the carrier and a second positioning means (L1-L3) able to cooperate with a third positioning means (s1, s2, s3) of an optical arrangement including the optical device to realize the coupling. The first positioning means (P) is constituted by a plate having a substantially V-shaped lateral cut-out portion wherein the optical termination (T1/T5) fits and the second and third positioning means are realized by upstanding tongue shaped elements and edges of cut-out parts of the carrier and of the optical arrangement. <IMAGE>   <IMAGE>
Patent DE-69500806-T2 (DE)
Inventor: KING RODERICK F G
IPC: A23L2/38
Filed: 1995-02-16
Granted: 1998-04-09
Abstract: PCT No. PCT/GB95/00331 Sec. 371 Date Nov. 1, 1996 Sec. 102(e) Date Nov. 1, 1996 PCT Filed Feb. 16, 1995 PCT Pub. No. WO95/22260 PCT Pub. Date Aug. 24, 1995A sports drink comprises an aqueous solution including a saccharide selected from: galactose, a galactose containing disaccharide or oligosaccharide, sorbitol, lactose, fructose or mixtures thereof and optionally including not more than 1.25% w/v of glucose.
Patent DE-69518661-T2 (DE)
Inventor: DREIER ANN
IPC: A61F13/15
Filed: 1995-11-30
Granted: 2001-05-03
Abstract: A disposable diaper having a waist pocket cuff is disclosed. The pocket cuff has first and second portions separable along a predetermined line of weakness. The predetermined line of weakness can comprise a line of spaced apart perforations.
Patent DE-69532041-T2 (DE)
Inventor: AGBO FRANCIS
IPC: A23C11/10
Filed: 1995-08-15
Granted: 2004-07-01
Abstract: A particulate dry mix foaming creamer comprises a conventional particulate creamer for coffee beverages and the like together with a foam generating component comprising a food grade acidulant and an alkali metal carbonate or bicarbonate. A dry mix instant hot cappuccino product in accordance with the invention comprises a water soluble coffee component, the foam generating component, an optional creamer component, and an optional sweetener component. Cappuccino beverages are prepared by mixing a liquid component and the dry mix composition and heating. The liquid component may comprise milk or water. Heating, preferably microwave heating, may be carried out by pre-heating the liquid component or by heating after addition of the liquid component, or by a combination of these heating techniques.
Patent DE-69534671-T2 (DE)
Inventor: LEVY J
IPC: A61L27/50
Filed: 1995-10-20
Granted: 2006-07-13
Abstract: Naturally-derived bioprosthetic materials are treated with epoxide crosslinking agents. In some embodiments, the tissue is crosslinked with low molecular weight epoxides in aqueous solutions at high pH levels. In other embodiments, the tissue is crosslinked at physiologic pH levels with epoxide crosslinking agents catalyzed with tertiary or quaternary amines, such as Tris or imidazole. In an advantageous embodiment, bioprosthetic tissue is crosslinked and derivatized with an anticalcification agent, such as a polyphosphonate anticalcification agent, using a polyphosphonate:polyepoxide monoadduct.
Patent DE-69600717-T2 (DE)
Inventor: JACOBS THOMAS GERARDUS MARIA
IPC: A22B5/00
Filed: 1996-07-02
Granted: 1999-02-25
Abstract: The invention relates to a method for releasing intestines in a carcass opened on the abdominal side, in particular a sheep, pig or cattle carcass, comprising the successive steps of:   placing at least one bracket member (9) in an operative position between the peritoneum and the abdominal wall, moving the bracket member (9) substantially parallel to the spinal column whereby the peritoneum with organs arranged therein is at least partially released from the abdominal wall, and carrying the bracket member (9) from the operative position out of the carcass.   The invention also relates to a device for performing this method. <IMAGE>
Patent DE-69627069-T2 (DE)
Inventor: KAWAMURA MAKOTO
IPC: H04N9/877
Filed: 1996-01-30
Granted: 2004-01-22
Abstract: Encoded data is reversely reproduced by decoding each picture only once and using only as many frame memory sections as are needed in a normal playback operation. A picture header detector (34) detects a picture header from data read out from a video code buffer (10) to identify the type of picture. The picture type information controls a picture data selecting circuit (35) for selecting frames of I and P pictures equal in number to the number of frame memory sections in a frame memory bank (16). The selected frames are supplied to an inverse VLC circuit (11) to be decoded, starting at the head of a GOP with an I picture. The decoded I and P pictures are stored in the frame memory bank (16) and transmitted to a display unit (18), starting with the temporally most recent picture and reading backward.
Patent DE-69634918-T2 (DE)
Inventor: HERMON-TAYLOR JOHN
IPC: A61K48/00
Filed: 1996-12-23
Granted: 2006-05-18
Abstract: The invention provides a nucleotide sequence representing a pathogenicity island found in species of pathogenic mycobacteria. The islands are shown as SEQ ID NOS: 3 and 4 and comprises several open reading frames encoding polypeptides. These polypeptides and their use in diagnosis and therapy form a further aspect of the invention.
Patent DE-69637483-T2 (DE)
Inventor: HAMERS RAYMOND
IPC: C07K16/00
Filed: 1996-04-25
Granted: 2009-08-06
Abstract: The present invention relates to fragments, especially variable fragments of immunoglobulins which are by nature devoid of light chains, these fragments being nevertheless capable of exhibiting a recognition and binding activity toward specific antigens. The present invention further relates to the use of such immunoglobulin fragments formed of at least one heavy chain variable fragment or derived therefrom, for therapeutic or veterinary purposes and especially for passive immunotherapy or serotherapy.
Patent DE-69720505-T2 (DE)
Inventor: PAREKH BHIKHU
IPC: G01N27/447
Filed: 1997-12-01
Granted: 2004-03-04
Abstract: The present invention provides methods and apparatus for identifying, selecting and characterizing biomolecules in a biological sample. A two-dimensional array is generated by separating biomolecules present in a complex mixture. A computer-readable profile is constructed representing the identity and relative abundance of a plurality of biomolecules detected by imaging the two dimensional array. Computer-mediated comparison of profiles from multiple samples permits automated identification of subsets of biomolecules that satisfy pre-ordained criteria. Identified biomolecules can be automatically isolated from the two dimensional array by a robotic device in accordance with computer-generated instructions. A supported gel suitable for electrophoresis is provided that is bonded to a solid support such that the gel has two-dimensional spatial stability and the solid support is substantially non-interfering with respect to detection of a label, such as a fluorescent label, associated with one or more biomolecules in the gel. <IMAGE>
Patent DE-69725311-T2 (DE)
Inventor: UBER E
IPC: A61M31/00
Filed: 1997-05-09
Granted: 2004-08-05
Abstract: The present invention provides a number of pumping systems and injection systems particularly useful for injecting a liquid medium into a patient. In general, the pumping systems comprise a removable pumping unit. The removable pumping unit includes means for pressurizing the liquid medium via the rotational displacement of the liquid medium. The present invention also provides a pumping system comprising a pumping unit for pressurizing the liquid medium and a feedback-controlled drive means in connection with the pumping unit for providing a controlled powered drive to the pumping unit. The pumping system further comprises a flow meter for measuring the flow rate of the pressurized liquid medium exiting the pumping system and control means in communicative connection with the drive means for providing a control signal to control the powered drive provided to the pumping unit. The control means is suitable to receive a feedback signal from the flow meter corresponding to the flow rate of the pressurized liquid medium exiting the pumping unit. The control signal provided to the drive means is a function of the feedback signal.
Patent DE-69736806-T2 (DE)
Inventor: AKITA ROBERT
IPC: C12P21/08
Filed: 1997-03-07
Granted: 2007-08-09
Abstract: Antibodies are disclosed which bind to ErbB3 protein and further possess any one or more of the following properties: an ability to reduce heregulin-induced formation of an ErbB2-ErbB3 protein complex in a cell which expresses ErbB2 and ErbB3; the ability to increase the binding affinity of heregulin for ErbB3 protein; and the characteristic of reducing heregulin-induced ErbB2 activation in a cell which expresses ErbB2 and ErbB3.
Patent DE-69803066-T2 (DE)
Inventor: LANG RUDOLF
IPC: F04B39/00
Filed: 1998-05-09
Granted: 2002-07-04
Abstract: PCT No. PCT/EP98/02718 Sec. 371 Date Jun. 18, 1999 Sec. 102(e) Date Jun. 18, 1999 PCT Filed May 9, 1998 PCT Pub. No. WO98/54467 PCT Pub. Date Dec. 3, 1998Electric compressor comprising a piston provided with a respective head and a valve plate mounted between the head and the body of the cylinder and provided with a gas suction port, the head being provided with a protrusion adapted to be intermittently introduced in the suction port substantially in the top dead-center position of the piston. The piston is provided externally, in the portion thereof which is opposite to the head side, with a recess that is accessible from the outside and is orientated towards the inner volume of the piston, the recess penetrating the body of the piston down to a depth which is at least equal to the height of the protrusion above the plane of the head.
Patent DE-69805187-T2 (DE)
Inventor: SAMWAYS LEONARD
IPC: F16C39/06
Filed: 1998-02-11
Granted: 2003-03-13
Abstract: A centrifugal separator comprises a housing through which extends a spindle on which is mounted a centrifuge rotor. The rotor is mounted on journal bearing bushes that are lubricated by the liquid supplied at pressure to the rotor and the weight of the liquid-filled rotor is carried by magnetic repulsion thrust bearing comprising permanent magnets secured one each to the housing and rotor. The spaced magnets run without contact noise and frictional losses, improving rotational speed available from the supply pressure, and lateral (radial) instability that is inherent between repelling magnets and normally disliked puts a radial bias on the journal bearings which may result in quieter running by inhibiting vibration, particularly when the journal bushes are starved of liquid supply during wind-down. Alternatively or additionally, supply pressure induced lift of the rotor may be borne by a magnetic repulsion thrust bearing. The magnets may be permanent and/or electromagnets.
Patent DE-69815867-T2 (DE)
Inventor: AALTONEN RAMI
IPC: D21F5/18
Filed: 1998-05-29
Granted: 2004-05-13
Abstract: A method and flotation dryer unit effects drying of a web such as a coated paper web. The flotation dryer unit advantageously includes several nozzle boxes extending across the web for feeding drying air toward the web to be dried, a distribution chamber for drying air for leading the dry air into the nozzle boxes, and a suction chamber for gathering the drying air led toward the web from the web area and for directing it to the side of the web. The suction chamber is divided into an equalizing space and an air transport chamber by a perforated plate for equalizing the return air flow occurring from the web area.
Patent DE-69816544-T2 (DE)
Inventor: FUERTES PATRICK
IPC: D21H17/16
Filed: 1998-09-08
Granted: 2004-06-09
Abstract: Transforming a starchy material comprises heating it at 60 - 100 degrees C for 5 - 30 minutes, in a dry phase with a chemical agent, to bring about hydrolysis. Starchy material is transformed by a continuous process of chemical fluidification in a dry phase, (i.e. less than 25% humidity, preferably 8 - 22% humidity), using a chemical agent having a hydrolyzing action, the temperature being 60 - 100 degrees C and the period of action being 5 - 30 minutes. The starchy material used may be any of the following: raw starch, flours, products resulting from the etherification, esterification, sulfonation, oxidation, cationization, hydroxy alkylation, and/or acetylation of these starches and flours, and their mixtures. The chemical agents used may be mineral or organic acids or (per)oxidizing agents, in liquid, solid, or gaseous form. The use of 0.01 - 0.4% hydrochloric or sulfuric acids, calculated on dry weight of starchy material, is especially preferred. During or after this process the product may be transformed by chemical modification, such as etherification, esterification, sulfonation, cationization, hydroxy alkylation or acetylation. Independent claims are also included for cationic starchy material having a water fluidity of at least 65, preferably 70 - 79, a nitrogen content of 0.3 - 0.5%, preferably 0.3 - 0.48% expressed in relation to the weight of dry cationic starchy material.
Patent DE-69825988-T2 (DE)
Inventor: FANTUCCI MARIO
IPC: C07B63/02
Filed: 1998-05-04
Granted: 2005-09-15
Abstract: A method for removing heavy metals, selected from palladium, tin and nickel, from heavy metal complexes with thiazole compounds in aqueous or alcoholic solution, by precipitation as sulfides, characterised in that such solutions are treated with a water-soluble ammonium, alkaline or alkaline-earth sulfide.
Patent DE-69831870-T2 (DE)
Inventor: MOE N
IPC: H01B13/016
Filed: 1998-08-06
Granted: 2006-07-20
Abstract: The present invention is a flexible low loss coaxial cable comprising a cylindrical plastic rod, an inner conductor surrounding the plastic rod, a dielectric layer surrounding the inner conductor, and a tubular metallic sheath closely surrounding the dielectric layer. The coaxial cable can further include a protective polymer jacket surrounding the sheath. The cylindrical plastic rod supports the inner conductor in bending and can be formed around a central structural member. The present invention also includes a method of making flexible coaxial cable.