baber/WOPTO huggingface dataset:
Patent JP-2002514919-A (JP)
Title: 多価ライブラリーおよびポリクローナルライブラリー
IPC: C12N15/09
Filed: 1998-04-03
Abstract: (57)【要約】
本発明は、特に、従来の提示方法における２つの関連した、しかし自己完結的な改善に関する。第１の改善は、目的の標的を有するようなライブラリーのアフィニティースクリーニングに先立って、１コピーより多いポリペプチドを提示するメンバーについて、従来の提示ライブラリーを富化する方法を提供する。これらの方法は、全長のコード配列を保持する大多数のメンバーが、標的に対して特異的なアフィニティーを有するポリペプチドをコードする、多様な集団を達成し得る。第２の局面において、本発明は、個々のメンバーのクローン的な単離の必要なしで、富化されたライブラリーの提示されたポリペプチドをコードする核酸を、提示ベクターから発現ベクターにサブクローニングする方法を提供する。これらの方法は、抗体のポリクローナルライブラリーや、例えば、診断薬や治療薬のような使用のための他のポリペプチドを生じる。
Patent JP-2001524969-A (JP)
Title: 複合糖質蛍光標識試薬
IPC: C12Q1/68
Filed: 1998-04-02
Abstract: (57)【要約】
蛍光色素、一以上の糖又は糖質残基であって水溶性を付与するもの、及び反応性基であって試薬を基質へ共有結合することを許容するものを備えた、水溶性複合糖質蛍光標識試薬を開示する。式（I）の複合糖質蛍光標識試薬。これらの複合糖質は、その糖残基のために水溶性が高い。この性質は、細胞性物質への非特異的結合を低減し、標識済基質の沈殿を低減し、蛍光の消滅を阻害することが期待され、有機溶媒にのみ可溶である従来の多くの蛍光標識試薬とは異なり、複合糖質を完全な水溶液中で使用することを可能にする。
Patent JP-2001514528-A (JP)
Title: 天然プレセニリン１ヌルバックグラウンド上で非天然野生型および家族性アルツハイマー病突然変異プレセニリン１タンパク質を発現するトランスジェニック動物
IPC: G01N33/50
Filed: 1998-05-13
Abstract: (57)【要約】
本発明は、天然プレセニリン（1）を欠くトランスジェニック非ヒト動物胚、および非天然プレセニリン（1）のみを有するトランスジェニック非ヒト動物に関する。該トランスジェニック動物およびそれに由来する細胞は、プレセニリン（1）の発現パターン、活性およびモジュレーターの研究、アルツハイマー病におけるプレセニリン（1）の役割の研究、および中枢神経系の障害の研究において使用することができる。
Patent JP-2001527571-A (JP)
IPC: A61K35/407
Filed: 1998-05-25
Abstract: The invention relates to the field of transplantation, specifically to the field of transplantation of isolated cells. The invention provides a method to allow cell transplantation as a method to replace organ transplantation. Anti-integrin (poly)peptides significantly block attachment of cells to both vessel walls and tissue in an in vitro binding assay. Blocking of integrins by incubation with blocking (poly)peptides significantly decreases the number of cellular aggregates after in vivo cell transplantation, and has a significant increasing effect on cellular homing in the recipient tissue. Blocking of integrin strongly improves transplanted cell survival in the recipient tissue after transplantation.
Patent JP-2002512767-A (JP)
Title: 無線システムのネットワーク要素間に接続を確立する方法
IPC: H04W24/00
Filed: 1999-04-28
Abstract: (57)【要約】
本発明は、テレコミュニケーション接続により作動的に相互接続されたネットワーク要素としての１つ以上のベースステーション(316,324,326,328,334,336)、ベースステーションコントローラ(302)及びネットワークマネージメントシステム(300)を備えた無線システムにおいてネットワーク要素間に接続を確立する方法及び無線システムに係る。ネットワーク要素間の情報は、タイムスロットに分割されたフレームにおいて送信される。ベースステーションコントローラは、１つ以上のベースステーションを制御する。ネットワーク要素識別情報が、インストールされるべきネットワーク要素に供給され、そしてネットワーク要素がテレコミュニケーション接続によりシステムに物理的に接続される。ネットワーク要素を迅速且つ確実にインストールできるようにするために、ベースステーションコントローラに接続することが許されたベースステーションの識別情報が予め決定され、そしてベースステーションコントローラにまだ接続されていないベースステーションの識別情報が与えられたことをベースステーションコントローラが検出した場合に、ベースステーションコントローラは、ベースステーションコントローラがネットワーク要素との通信に使用するフレームの少なくとも幾つかにおいて通信チャンネルを送信する。物理的なインストールの後に、インストールされるべきネットワーク要素は、テレコミュニケーション接続により受け取られたフレームを、ベースステーションコントローラにより送信された通信制御チャンネルについてサーチし、そしてその見つかった通信チャンネルによりベースステーションコントローラへの接続を確立する。
Patent MX-151525-A (MX)
Inventor: GREENWOOD JOHN
IPC: F16G5/16
Filed: 1980-09-12
Abstract: A driving belt (1) formed from detachable, flexible, elongate links (3) arranged in a staggered, overlapping relationship. Each link (3) is provided with a stud (39, 41, 43) which is rotatable relative to the link and has a head (39, 41, 43) which is shaped to pass through perforations (35, 37) in other links (3) when the head is orientated correctly relative to the perforations but not otherwise. The arrangement allows simple assembly and disassembly of the belt without any lateral distortion of the material of the links.
Patent NZ-217388-A (NZ)
Title: Repressible yeast promoters and activation sequences
Inventor: HINNEN ALBERT
IPC: C12N15/81
Filed: 1986-08-28
Abstract: Novel upstream activation sites of the yeast PHO5 gene are used to produce inducible yeast hybrid promoters. The yeast hybrid promoters can be used to control transcription of a polypeptide coding region foreign to yeast in a yeast expression vector.
Patent NZ-220195-A (NZ)
Title: 2-pyridyl-penem derivatives and pharmaceutical compositions
Inventor: LANG M
IPC: C07D499/00
Filed: 1987-05-05
Abstract: Compounds of the formula    <IMAGE>  (I)  in which R1 represents lower alkyl substituted by hydroxy or by protected hydroxy, R2 represents carboxy or functionally modified carboxy, and R3 represents optionally substituted 3-pyridyl or optionally substituted 4-pyridyl, and pharmaceutically acceptable salts of such compounds, have antibacterial activity. The compounds of the formula I can be manufactured according to processes known per se.
Patent NZ-224830-A (NZ)
Title: Thiophene sulphonamide derivatives and pharmaceutical compositions
Inventor: BALDWIN JOHN J
IPC: C07D333/34
Filed: 1988-05-30
Abstract: Aryl (or aralkyl)-sulfonylthiophene-2-sulfonamides containing a basic functional group as a substituent are efficacious in the treatment of elevated intraocular pressure and glaucoma following topical ocular administration.
Patent NZ-225032-A (NZ)
Title: Method of extracting protein from microbial cells
Inventor: PATRONI JOSEPH JOHN
IPC: C12Q1/24
Filed: 1988-06-15
Abstract: A method for the recovery of proteins in a solubilized form from host cells including providing a source of host cells incorporating a synthesized or expressed protein; providing a source of at least one cationic surfactant; and treating the host cells with at least one cationic surfactant, in an amount sufficient to effect solubilization of the proteins.
Patent NZ-225345-A (NZ)
Title: 3-demethyl-4-fluoromevalonic acid derivatives and intermediates for their synthesis
Inventor: BERGMANN ANDREAS
IPC: C07D405/06
Filed: 1988-07-08
Abstract: 3-Desmethyl-4-fluoromevalonic acid derivatives of the formula I and the corresponding dihydroxycarboxylic acid derivatives of the formula II 
<IMAGE>
 in which R, X and Y have the meanings given, processes for the preparation of these compounds, their use as medicaments and pharmaceutical preparations are described. Novel intermediates for the preparation of the compounds of the formula I or formula II are additionally described.
Patent NZ-226725-A (NZ)
Title: Cough mixtures containing phenol
Inventor: SORRENTINO JAMES VINCENT
IPC: A61K31/485
Filed: 1988-10-26
Abstract: Novel antitussive and anesthetic liquid compositions of matter for oral use comprising an effective oral antitussive drug and phenol; and method of using same.
Patent NZ-228549-A (NZ)
Title: Packet switch: bus arbitration and priority with multiple processors
Inventor: MAKRIS PERRY
IPC: H04L12/56
Filed: 1989-03-30
Abstract: A packet switch receives data and processes it for assembly into packages. A bus allows communication between each of the data processing units of the switch and one or more storage units for storing the data packets. Arbitration for deciding which of the processing units will be granted access to the bus is performed by a system which selectively and alterably designates any of at least two different levels of priority of access to the bus for each of the processing units, and the relative percentages of time of access for the different priorty levels. The system assures greater access to the bus by those of the processing units having the higher level of priority. If communication is provided by two buses, the requests for access are alternated between them. The arbitration system provides selective access to the bus in any of a plurality of bus cycles including a read cycle, a write cycle and a read/modify/write cycle, and grants a request for access from a higher priority processing unit within one bus cycle.
Patent NZ-235015-A (NZ)
Title: Method of amplifying target nucleotide sequence and detection of alleles indicative of an inherited disease or trait
Inventor: NEWTON CLIVE ROBERT
IPC: C12Q1/6853
Filed: 1990-08-22
Abstract: A method for the amplification of a target nucleotide sequence using a first primer comprising 1) a target binding nucleotide moeity which is substantially complementary to the desired portion of the target nucleotide sequence; and 2) a polynucleotide tail; the first primer being such that whilst an extension product thereof may itself serve as a template for primer extension to form an amplification primer extension product, formation of an amplification primer extension product comprising a sequence complementary to the polynucleotide tail is inhibited.
Patent NZ-235134-A (NZ)
Title: Process for enzymatic oxidation of fatty acids to, preferably, produce methyl ketones; apparatus
Inventor: HUMPHREY MARTIN
IPC: C12M1/40
Filed: 1990-08-31
Abstract: This invention relates to a process for enzymic oxidation of a fatty acid to produce an oxidation product in the presence of water and oxygen characterised in that the fatty acid, water and enzyme for the oxidation are substantially uniformly distributed throughout a porous bed of solid support material in the substantial absence of a continous liquid phase, oxygen is passed through the porous bed and the oxidation product is recovered from the porous bed. The invention is of particular value for production of methyl ketones from saturated fatty acids. Apparatus for carrying out the process is also novel and comprises a sealable vessel (1) that can contain a porous bed 4 of solid support material, a gas inlet (12) for supplying oxygenating gas to the reactor, a gas outlet (13), passage means (7) defining a plurality of upwardly extending passages that can open along their length into the bed and that communicate with the inlet (12) and that are preferably spaced 5 to 20cm (preferably 5 to 15cm) apart, and means for forcing oxygenating gas through the inlet and along and out from the passages and into the bed.
Patent NZ-264039-A (NZ)
Title: Contact lens mould: one mould half has peripheral ring that engages excess lens material and separates it from moulded lens
Inventor: SU KAI C
IPC: B29C33/00
Filed: 1994-07-19
Abstract: A lens mold includes first (1) and second mold (2) members respectively having a concave (3) surface and a convex surface (4) for defining therebetween a lens cavity. One of the first and second mold members is configured to mechanically engage a ring of excess lens material upon polymerization of the lens material. Alternately, one of the first and second mold members includes a material formed along the periphery of a lens cavity (5) which causes the ring of excess lens material thereto. Furthermore, one of the first and second mold members is formed of a relatively transparent plastic material and includes an outer surface having an optical finish to permit optical inspection of a lens located on one of the concave and convex surfaces. Alternately, one of the first and second mold members is formed of a relatively opaque plastic material and includes an inner surface having an optical finish to permit optical inspection of a lens located on one of the concave and convex surfaces. <IMAGE>
Patent NZ-280974-A (NZ)
Title: Lactic bacterium dna coding for enzymes involved in exopolysaccharide (eps) production and its use
Inventor: MOLLET BEAT
IPC: C07K14/315
Filed: 1996-02-13
Abstract: A chromosomal DNA fragment coding for one or more enzymes involved in the biosynthesis of an exopolysaccharide (EPS) is claimed, where the fragment is capable of restoring EPS prodn. upon transformation of a non-EPS-producing lactic acid bacterium or of modifying EPS structure upon transformation of an EPS-producing lactic acid bacterium.
Patent NZ-285426-A (NZ)
Title: Nutritional formulation comprising a blend of amino acids limiting acetyl methionine, methionine, and glutamic acid to reduce off-flavours
Inventor: SMITH STEPHEN LEYLAND
IPC: A23L1/305
Filed: 1995-05-15
Abstract: A nutritional formulation comprises a blend of amino acids and is characterised by the presence of not more than 20 % by weight acetylmethionine, not more than 3 % by weight methionine, and not more than 0.1 % by weight glutamic acid, and a balancing percentage of other amino acids, the percentages being based on the total weight of the amino acids in the formulation. The formulation does not have off-flavours which have been found to be caused by the presence of methionine and glutamic acid in amounts greater than those indicated.
Patent NZ-291492-A (NZ)
Title: Optical scanning to characterise surface of 3-d object: overlapping scans combined
Inventor: FLOCKHART CHRISTOPHER PETER
IPC: G01P15/00
Filed: 1995-08-22
Abstract: A scanning arrangement has a device (40) for projecting a two-dimensional optical pattern on a surface (35) of a scanned object. A two-dimensional photodetector (34') is mounted within a hand-held scanning device and outputs scan files of 3D coordinate data of overlapping surface portions of the object. The surface portions defined by these scan files are registered by appropriate rotations and translations in a computer, which are determined either from the outputs of a gyroscope (51) and an accelerometer (50) or by mathematical processing of the surface portions, e.g., involving detecting and location of common features.
Patent NZ-302670-A (NZ)
Title: Use of 2,3-dihydro-imidazo[2,1-b]benzothiazole derivatives to treat degenerative disorders and ageing of the nervous and vascular systems
Inventor: LESAGE ANNE SIMONE JOSEPHINE
IPC: A61P25/00
Filed: 1996-02-14
Abstract: The use of a 2,3-dihydro-imidazo[2,1-b]benzothiazole derivative for the manufacture of a medicament for the therapeutic or prophylactic treatment of humans suffering from neuronal loss from the central and peripheral nervous system which is associated with oxidative damage or injury.
Patent NZ-318282-A (NZ)
Title: Pharmaceutical formulation containing amoxycillin and clavulanate in a weight ratio of 12:1 and 20:1
Inventor: BURCH DANIEL JOSEPH
IPC: A61P31/04
Filed: 1996-09-05
Abstract: hese pharmaceutical formulations comprise amoxycillin and clavulanate in a ratio of from 10:1 to 20:1 and are of use in the empric treatment of infections potentially caused by DRSP.  Divisional filed as 337246
Patent NZ-332901-A (NZ)
Title: Fluid chilling vessel, includes adsorbent, and heat transfer elements to conduct heat from vessel walls to de-sorbed gas and adsorbent
Inventor: GARRETT MICHAEL ERNEST
IPC: F25B35/04
Filed: 1998-11-19
Abstract: A fluid chiller cartridge  2 includes a thin walled aluminium vessel 4 containing a number of aluminium "cups" containing layers of carbon adsorbent 8.  The rim of each cup is corrugated to allow gas flow to and from the adsorbent.  In use the cups would completely fill the cartridge, and act as heat transfer elements.  Before use, the cartridge is charged with a gas, such as carbon dioxide, under pressure.  This gas is adsorbed into the adsorbent.  To chill a fluid, the cartridge is placed in a fluid, and a valve opened or the wall ruptured to release the gas pressure within the cartridge, causing gas to desorb from the adsorbent. Since the desorption process is endothermic, the temperature of the adsorbent drops, and heat is absorbed from the fluid.
Patent NZ-505251-A (NZ)
Title: Snowboard body designed with beam design principles to form a circular arc
Inventor: STUBBLEFILED DONALD P
IPC: A63C5/03
Filed: 1998-11-19
Abstract: A snowboard 10 designed to maintain a riding edge with an arc of constant curvature has a relatively thick base in the mounting zones 24, 28 beneath each of the rider's feet and a relatively thin base in the area 30 between the two mounting zones. Consequently, when the snowboard is being used, the portions of the snowboard coming in contact with the surface of the snow will substantially lie on segments of a circular arc, and the back half of the snowboard will substantially follow in the track of the front half of the snowboard. The curvature of the snowboard in response to the application of forces by its rider is a function of the Area Moment of Inertia of the transverse cross-sectional areas along the snowboard's length, which is in turn a function of the geometry of the transverse cross-section A-A.
Patent NZ-505749-A (NZ)
Title: Augmentation of electrical conduction and contractibility by biphasic cardiac pacing administered via the cardiac blood pool
Inventor: MOWER MORTON M
IPC: A61N1/36
Filed: 1999-01-13
Abstract: The electrical cardiac pacing apparatus functions to augment electrical conduction and contractibility by biphasic cardiac pacing. The apparatus includes leads for applying the electrical stimulation to a cardiac blood pool. A stimulation generator, connected to the leads, generates the biphasic electrical waveform comprising a first stimulation phase with a predefined polarity, amplitude and duration. There is also a second stimulation phase with a predefined polarity, amplitude and duration. The two phases are applied sequentially. Contrary to current thought, anodal stimulation (102) is first applied and followed by cathodal stimulation (108). In this fashion, pulse conduction through the cardiac muscle is improved together with the increase in contractibility.
Patent NZ-511834-A (NZ)
Title: Fluid pressure-reducing valve with a rotary hand wheel having angular travel less than one turn, and given pressure values at predetermined angular positions
Inventor: CANNET GILLES
IPC: F16K1/30
Filed: 2001-05-21
Abstract: The pressure-reducing valve has hand wheel 110 arranged to provide specific pressure values at given angular locations. The wheel 110 moves less than one full turn. Typically, stops 115 are provided, and the wheel acts via a screw thread and cam arrangement to move disc 119 as shown.
Patent NZ-513762-A (NZ)
Title: Human suppressor of fused
Inventor: MURONE MAXIMILIEN
IPC: C12N15/12
Filed: 2000-03-02
Abstract: The present invention is directed to novel polypeptides having homology to a polypeptide suppressor of the Drosophila melanogaster fused protein and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent NZ-514165-A (NZ)
Title: Supported catalysts and olefin polymerization processes utilizing same
Inventor: BANSLEBEN DONALD A
IPC: C08F4/80
Filed: 2000-03-17
Abstract: Disclosed is a catalyst for olefin polymerisation having the formula ST-Cat, wherein Cat is of formula (II) or (III), wherein S is an inert organic or inorganic macromolecule and T is an optionally fluorinated C2-40 hydrocarbylene, hydrocarbyloxyene, hydrocarbylsilane or hydrocarbylborane.
Patent NZ-514235-A (NZ)
Title: Pressure agglomerated system comprising a cyclopropene encapsulated in a molecular encapsulation agent (e.g. a cyclodextrin)
Inventor: KOSTANSEK EDWARD CHARLES
IPC: A01N27/00
Filed: 2001-09-17
Abstract: The pressure-agglomerated composition comprises: i) A cyclopropene of the formula shown; where R is H or a substituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, phenyl, or naphthyl group; where the substituents are independently halogen, alkoxy, or substituted or unsubstituted phenoxy. ii) A molecular encapsulation agent (e.g. cyclodextrin) within which the cyclopropene is encapsulated. iii) Optionally one or more adjuvants.
Patent NZ-514948-A (NZ)
Title: Pesticidal indazole or benzotriazole derivatives
Inventor: MATHEWS CHRISTOPHER JOHN
IPC: A01N43/80
Filed: 2000-04-04
Abstract: A compound of formula (I) wherein G is either (i) or (ii), where M1 or M2 is bonded to A; n is 0 or 1; when G is (i), D is S, NR7, CR8=CR9, CR8=N, CR8=N(O), N=CR9 or N(O)=CR9; when G is (ii), D is S or NR7; E is N, N-oxide or CR10; M1 is OC(=Y), N(R11)C(=Y), N=C(OR12), N=C(SR13) or N=C(NR14R15) where O or N is the atom of attachment to the ring containing D and E; M2 is N-C(=Y) where N is the atom of attachment to the ring containing D and E; Y is O, S or NR16; J is N or CR17; and A, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14 and R15 are each certain organic or inorganic groups. These compounds are useful in fungicidal, insecticidal, acaricidal, molluscicidal and hematicidal compositions.
Patent NZ-515367-A (NZ)
Title: Method and kitset for sampling and storage of biological samples
Inventor: SHIRLEY KEVIN JOHN
IPC: C12Q1/68
Filed: 2000-04-07
Abstract: A method for collecting and storing a biological sample, comprising: (a) providing a sampling strip, one face of which has an absorbent area impregnated with a DNA stabilising composition, and an adhesive area, the other face of which covers and protects the sampling area, (b) collecting a biological sample on the absorbent area, (c) providing an identification substrate having a surface area to receive the sampling strip, (d) applying the sampling strip containing the biological sample to the substrate so that the absorbent area is enveloped between the outer face of the strip and the substrate, (e) marking the substrate and/or the sampling strip either before or after, during or after the applying stage with indicia to identify the source of the biological sample, and (f) storing the combined marked substrate/strip.
Patent NZ-522606-A (NZ)
Title: Backflow preventer apparatus and method with integration of shut-off valves
Inventor: DUNMIRE CHARLES W
IPC: E03B7/07
Filed: 2001-04-27
Abstract: Backflow prevention is provided in connection with a device having one or more shut-off valves integrated with a double-check-valve backflow prevention device and/or housing. Preferably, a single housing encompasses two backflow preventer check valves, and upstream and downstream shut-off valves. Typically, end users cannot readily remove the shut-off valves (and/or their housing) from the backflow preventer check valves (and/or their housing). No flange or other connection between shut-off valves and backflow preventer check valves (and/or their housing) is required, reducing size, weight and labour requirements. The system can substantially reduce or eliminate potential for installation of double-check-valve backflow preventer devices without shut-off valves
Patent NZ-524247-A (NZ)
Title: Pectin film compositions
Inventor: SCOTT ROBERT
IPC: A61K47/38
Filed: 2001-08-21
Abstract: The invention concerns film-forming compositions containing pectin, at least one additional film-forming polymer and a setting system for use in pharmaceutical, veterinary, food, cosmetic or other products like films for wrapping food, aspics or jellies, preferably for predosed formulations like soft or hard capsules, as well as aqueous solutions of the compositions for the manufacturing of said products.   <IMAGE>
Patent NZ-524292-A (NZ)
Title: 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents
Inventor: MICETICH RONALD GEORGE
IPC: A61K31/4439
Filed: 2001-09-14
Abstract: Syn isomers of racemates and optical isomers of 3-(heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids of formula (I) and their use in treating the infections caused by gram-negative pathogenic bacteria are disclosed.
Patent NZ-525000-A (NZ)
Title: Tablet dispenser for dispensing individual tablets
Inventor: POLLOCK NEIL
IPC: B65D83/04
Filed: 2001-10-12
Abstract: There is provided a dispenser comprising a container body (10), a storage region (12) which is disposed within the container body (10) and which in use contains a multiplicity of items to be individually dispensed, a dispensing outlet (14), a passage between the storage region (12) and the dispensing outlet (14), a valve member (38) disposed between said storage region (12) and said outlet (14) moveable between an open position and a closed position, a stop member (117) spaced from said valve member (38) so as to define a passage region (24) of a size to accommodate an item to be dispensed, said stop member (117) being moveable into and out of a closed position in which it prevents passage of an item through said passage region (24), and manually operable means (34) for moving said valve member (38) and said stop member (117).