baber/WOPTO huggingface dataset:
Patent AU-2019414550-A1 (AU)
Title: Fak inhibitor and drug combination thereof
Inventor: DU WU
IPC: A61P35/00
Filed: 2019-12-24
Abstract: A deuterated compound as represented by formula (I) or an optical isomer, a tautomer, a pharmaceutically acceptable salt, a prodrug, a hydrate, or a solvate thereof. Compared with a compound before deuteration, the deuterated compound shows better pharmacokinetics, higher maximum plasma drug concentration, higher exposure, and longer half-life, and has more excellent metabolic performance. Moreover, the deuterated compound can effectively inhibit FAK activity, and has good application prospect in preparation of FAK inhibitors and/or drugs for treating cancer. In addition, the use of the deuterated compound in combination with an anti-cancer drug (such as a PD-1 inhibitor) can achieve a synergistic effect, thereby significantly improving the tumor suppression effect, and providing a better choice for clinical cancer treatment. (I)
Patent AU-2019473212-A1 (AU)
Title: Fracture fixation plate
Inventor: BURKI PATRICK
IPC: A61B17/80
Filed: 2019-11-07
Abstract: The invention relates to a fracture fixation plate (1) which is suitable for application to a volar surface of a distal radius, wherein the fracture fixation plate (1) has an elongated body section (2), which has a free proximal end (3) and a distal end (4), on which an ulna head section (5) and a radius head section (6) connects, which diverge distally from one another, wherein the two head sections (5; 6) are each independently connected to the distal end of the body section (2) via a corresponding neck section (51; 61), the body section (2) and the two head sections (5; 6) are provided with a number of threaded holes (7) for receiving bone securing elements (8) and the body section (2) also has an elongated compression recess (9), and the fracture fixation plate (9) has a bone contact surface (10) and an opposing surface (11). The bone contact surface (10) is designed such that it is convex in the region of the ulna head section (5) and the bone contact surface (10) is designed as a curved surface in the region of the radius head section (6).
Patent WO-2020198779-A1 (WO)
Inventor: HALL JONATHAN
IPC: G06T7/00
Filed: 2020-04-02
Abstract: L'invention concerne un système informatique d'intelligence artificielle (AI) permettant de générer un score de viabilité d'embryon à partir d'une seule image d'un embryon afin d'aider à la sélection d'un embryon à implanter dans une procédure de fécondation in vitro (FIV). Le modèle AI utilise une méthode d'apprentissage profond appliqué à des images dans laquelle la région de zone pellucide dans l'image est identifiée à l'aide d'une segmentation et de marques de réalité de terrain telles que la détection d'un battement de cœur lors d'un balayage ultrasonore à six semaines.
Patent WO-2021016650-A1 (WO)
Title: An orthodontic appliance including vibration source.
Inventor: PENN DAVID
IPC: A61C7/00
Filed: 2020-07-29
Abstract: An intra oral removable orthodontic assembly which influences teeth alignment. The assembly comprises; a intraoral attachment fitted to a seating unit and in use, held in place by intraoral engagement of the attachment with crowns of teeth of a wearer. The intraoral attachment is shaped to at least partially conform to at least a dental arch. The seating unit includes a power source, a PCB controller and a source of vibration transmissible to the attachment. The seating device vibrates in response to the source of vibration at a selected frequency between 60Hz -130Hz inducing a response in a selected tooth or group of teeth of a wearer. The attachment includes a working head having an array of displaceable formations responsive to said vibration and arranged to engage said teeth.
Patent AU-2020200297-A1 (AU)
Title: Methods and diets to protect against chemotoxicity and age related illnesses
Inventor: LONGO VALTER D
IPC: G01N33/68
Filed: 2020-01-15
Abstract: A method of improving longevity and/or alleviating a symptom of aging or preventing age related diseases is provided. The method includes a step in which the subject's average and type of daily protein intake, IGF-I, and IGFBP1 levels, and risk factors for overall mortality, cancer and diabetes are determined. With respect to protein consumption, the relative amounts of protein calories from animal and plant sources are determined. A periodic normal calorie or low calorie but low protein fasting mimicking diet with frequencies of every 2 weeks to 2 months is provided to the subject if the subject's average daily protein intake level and type and/or IGF-I levels, and/or IGFBP1 levels is identified as being greater or lower than a predetermined cutoff intake/level and if the subject is younger than a predetermined age. The method is also shown to alleviate symptoms of chemotoxicity.
Patent AU-2020200882-A1 (AU)
Title: Methods and compositions for treatment of glycogen storage diseases and glycogen metabolism disorders
Inventor: ARMSTRONG DUSTIN D
IPC: A61K38/47
Filed: 2020-02-07
Abstract: METHODS AND COMPOSITIONS FOR TREATMENT OF GLYCOGEN STORAGE DISEASES AND GLYCOGEN METABOLISM DISORDERS In certain embodiments, the present disclosure provides compositions and methods for treating Forbes-Cori and/or Andersen Disease and/or von Gierke Disease and/or Pompe Disease and/or Lafora Disease.
Patent AU-2020201004-A1 (AU)
Title: Injection system
Inventor: SUNDQUIST JOHN
IPC: A61M5/315
Filed: 2020-02-12
Abstract: Methods and systems for an injection system are provided. An example injection system (100) includes a container (102) for a pharmaceutical that is sealed at a proximal end with a plunger (106) having a pushing surface for engaging an inner surface of the hollow body. A plunger rod (108) extends axially from the proximal end of the container and is covered with a plunger rod cover (112). Removal of the cover activates the system and allows for delivery of the pharmaceutical product from the container by advancing the plunger within the container towards the seal. Figure 1
Patent AU-2020201548-A1 (AU)
Title: Compositions and methods for the treatment of meibomian gland dysfunction
Inventor: ALSTER YAIR
IPC: A61K35/04
Filed: 2020-03-03
Abstract: Described herein are compositions and methods for the treatment of meibomian gland dysfunction. Said compositions and methods comprise keratolytic agents, such as salicylic acid, selenium disulfide, or the like. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from meibomian gland dysfunction. -28-
Patent AU-2020201978-A1 (AU)
Title: Lid construction for breathing apparatus
Inventor: MILLER JEREMY LIVINGSTON
IPC: A61M16/16
Filed: 2020-03-19
Abstract: A breathing assistance apparatus has a lid and latch assembly configured for one-handed operation. The apparatus also includes a hinge assembly that separates when over-rotated but that reengages upon closing of the lid onto the main body of the apparatus. -20-
Patent AU-2020203810-A1 (AU)
Title: Headgear clip arrangement
Inventor: OLSEN GREGORY JAMES
IPC: A61M16/06
Filed: 2020-06-10
Abstract: A headgear connection assembly for a respiratory mask is configured to provide easy 
use and a reliable connection. The headgear connection assembly may include a clip 
attachment portion and a clip. The clip may include a hook, a headgear attachment loop, and 
5 one or more finger grips. The hook may be configured to include a central portion and two 
outer portions and an interference bump and to engage with a post of the clip attachment 
portion. The central and outer portions of the hook may be configured to flex independently 
of one another. The clip attachment portion may include geometry to limit rotation of the 
clip.  
10 
-22-
WO 2016/009393 PCT/1B2015/055412 
/1/1 
/00 
/115 
FIG.1I
Patent AU-2020203866-A1 (AU)
Title: Adapter assembly for an exercise rope
Inventor: PETTERSSON ROGER
IPC: A63B5/20
Filed: 2020-06-11
Abstract: An adapter assembly for releasably connecting an accessory connector (70) to 
an exercise rope (1) is provided. The assembly (2) comprises a connection part (30) being 
formed by a first portion (30a) and a second portion (30b), each having a bottom end (38b) 
5 and top end (38a), wherein the first and the second portion (30a, 30b) of the connection part 
(30) forms, at its bottom end (38b), a cavity configured to receive an end portion (la) of said 
rope (1), and wherein the top end (38a) of the connection part (30) is configured to releasably 
connect the accessory connector (70).
70 
2/10 
60 
50 
52 
30 
30a 30b 
4 
2 
8 
7 
g 2 
Fig. 2
Patent AU-2020204713-A1 (AU)
Title: Rechargeable battery kiosk for light electric vehicles
Inventor: STEINER MICHAEL
IPC: G07F15/00
Filed: 2020-01-03
Abstract: This disclosure generally relates to a battery kiosk that houses and distributes rechargeable batteries for light electric vehicles. The battery kiosk includes various visual indicators that are activated based on the individual's progress with a rechargeable battery exchange process.
Patent AU-2020206600-A1 (AU)
Title: Seating furniture chassis
Inventor: MACKERT MICHAEL
IPC: F16B12/38
Filed: 2020-01-10
Abstract: The invention relates to a seating furniture chassis, comprising a main body, fastening means (101) and at least one side part (100), wherein: the fastening means (101) are provided on the main body and the side part (100) can be detachably fastened to the fastening means (101), the fastening means (101) comprise a spring element (104) and a fastening element (102), the spring element (104) exerting a spring force on the fastening element (102), and when the side part (100) is fastened to the fastening means (101), the fastening element (102) is moved away against the spring force.
Patent AU-2020217659-A1 (AU)
Title: Methods for treating symptoms and disorders associated with lysosomal storage diseases
Inventor: CRAWFORD NIGEL PATRICK SOMERVILLE
IPC: A61K38/46
Filed: 2020-02-03
Abstract: This disclosure to methods for treating or preventing particular symptoms and disorders which are associated with lysosomal storage diseases using quinuclidine compounds of formula (I), optionally in combination with enzyme replacement therapy. This includes supranuclear gaze palsies, including horizontal and vertical saccadic gaze palsies, and cognitive deficits or gait disorders, such as in a patient having Gaucher disease or Niemann-Pick disease Type C. Also disclosed is a pharmaceutical composition comprising a quinuclidine compound for use in said methods.
Patent AU-2020228722-A1 (AU)
Title: Light system with anti-parallel leds
Inventor: DELVAUX MICHEL
IPC: H05B44/00
Filed: 2020-02-21
Abstract: Light system, comprising a driver to generate a DC current, at least one first group, a first group thereof comprising a first and a second LED connected in anti-parallel, at least one second group, a second group thereof comprising a first and a second LED connected in anti-parallel; said at least one second group being connected in series with said at least one first group, and control circuitry for selectively operating in at least one first mode and at least one second mode, wherein in the at least one first mode, the DC current is used to activate the first LED(s) of the at least one first group and/or the at least one second group; and in the at least one second mode, the DC current is used to activate the second LED(s) of the at least one first group and/or the at least one second group.
Patent AU-2020236329-A1 (AU)
Title: Modular manifold having at least two control modules for controlling operation of at least two hydraulic actuators of an earthmoving machine
Inventor: FERRAZ JR JOHN
IPC: E02F3/84
Filed: 2020-02-06
Abstract: A control module (302/304/306/308) for controlling an operation of a hydraulic actuator that is associated with an earthmoving machine (100) includes a body (312/314/316/318). The body (314) has a spool chamber (402) and a load sensing passageway (404) associated with the spool chamber (402). The body (314) also has a spool (406) positioned axially, and at least partially, within the spool chamber (402). The spool (406) is spring-biased by an end cap 408 located at a first end 410 of the body (314). The body (314) also has a pair of electrohydraulic spool actuators (452, 454) that are located at a second end (456) of the body (314) and operable to axially displace the spool (406) within the spool chamber (402). The pair of spool actuators (452, 454) are positioned in parallel and disposed adjacent to one another. The body (314) also has an inlet chamber (418) that is disposed parallel to the spool chamber (402) and in selective fluid communication with the spool chamber (402) via a spool supply passageway (420).
Patent AU-2020252050-A1 (AU)
Title: Lipocalin mutein for treatment of asthma
Inventor: AXELSSON LENA THERESE
IPC: A61K38/17
Filed: 2020-03-25
Abstract: The present invention relates to the treatment of asthma in a human subject by administering by inhalation a therapeutically effective amount of an anti-IL-4 receptor alpha (IL-4Ra) lipocalin mutein, or a variant or fragment thereof, to said subject, wherein the delivered dose of said lipocalin mutein, or variant or fragment thereof, is from about 0.1mg to about 160mg. The lipocalin mutein, or a variant or fragment thereof, may for example be administered at least once per day, once per day or twice per day.
Patent AU-2020271833-A1 (AU)
Title: HMOX1 inducers
Inventor: BIDDLE MARGARET
IPC: A61K31/4184
Filed: 2020-04-08
Abstract: The present invention is related to compounds of structure (I) as heme oxygenase 1 (HMOX 1) inducers. (Formula I) The present invention is also related a method of controlling the activity or the amount, or both the activity and the amount, of heme-oxygenase 1 in a mammalian subject. The definitions of the variables are provided herein.
Patent AU-2020273672-A1 (AU)
Title: Automated product locker for inventory control
Inventor: KERNICK EDWARD R
IPC: G06V30/224
Filed: 2020-05-13
Abstract: An example automated product locker is described herein. The automated product locker can include a housing and a drawer configured to be slidably stowable within the housing. The drawer can define a storage area configured to receive a product. The automated product locker can include a plurality of visual indicators configured to indicate respective positions of respective units of the product within the storage area, and a machine vision system configured to capture information about the product. The machine vision system can include an optical device. Additionally, the automated product locker can include a controller operably coupled to the machine vision system. The controller can be configured to inventory the product based, at least in part, on the information about the product, and cause one or more of the visual indicators that are associated with a desired unit of the product to actuate.
Patent AU-2020286493-A1 (AU)
Title: A bacterial platform for delivery of gene-editing systems to eukaryotic cells
Inventor: LINKE LYNDSEY M
IPC: C12N15/79
Filed: 2020-06-01
Abstract: A bacterial-mediated gene-editing delivery platform that uses invasive, non- pathogenic bacteria to deliver gene-editing cargo, including CRISPR/Cas systems, to eukaryotic cells. The bacteria contain a prokaryotic expression cassette encoding the gene-editing cargo.
Patent AU-2020287175-A1 (AU)
Title: Data sharing control methods and systems
Inventor: BAILEY MARK
IPC: H04L9/40
Filed: 2020-06-07
Abstract: Illustrative embodiments disclose systems for sharing, among a group of consumers, data provided by a contributor. Some embodiments are well-suited for real-time distribution of data developing from ongoing incidents, and may be useful, for example, for emergency management. Illustrative embodiments provide a cloud-based system having tenants that are data contributors and data consumers. The system receives, from each contributor, both data and sharing rules that dictate what data may be shared, and with whom (which consumer or consumers), and then provide data to such consumer or consumers according to the sharing rules.
Patent AU-2020353695-A1 (AU)
Title: Methods for treating acute wounds and improving outcomes
Inventor: SMIELL JANICE
IPC: A61K48/00
Filed: 2020-09-28
Abstract: The present disclosure provides methods for treating acute wounds and improving outcomes by applying to an acute wound a skin substitute that is an organotypic human skin equivalent comprising NIKS cells. In certain embodiments, the closed wound has improved vascularity, improved pigmentation, decreased thickness, decreased pain, increased pliability, increased surface area, decreased stiffness, decreased itching, improved color, or any combination thereof, as assessed by an observer or by the subject, as compared to an autograft or another skin substitute.
Patent AU-2020359143-A1 (AU)
Title: Ventilation member and wall material construction structure
Inventor: KATO TERUYUKI
IPC: E04B1/64
Filed: 2020-09-30
Abstract: Provided is a ventilation member suitable for ensuring the ventilation of a ventilation layer provided on the back side of a wall material. A ventilation member X according to the present invention is a ventilation member that can be attached to a wall material, and includes a fixed plate portion 10, a top plate portion 20, a partition plate portion 30, a bottom plate portion 40, a front plate portion 50, and a first baffle plate portion 61. The fixed plate portion 10 has a first surface that abuts against a building framework, and a second surface on a side opposite to the first surface, and includes a first end portion 13 located on one side in a state in which the ventilation member X is attached to the wall material, and a second end portion 14 located on another side. The top plate portion 20 extends from the first end portion 13 of the fixed plate portion 10 on the second surface side. The partition plate portion 30 extends from the top plate portion 20 in a direction from the first end portion toward the second end portion of the fixed plate portion 10. The bottom plate portion 40 extends from the partition plate portion 30 in a direction away from the fixed plate portion 10. The front plate portion 50 extends from the bottom plate portion 40 in a direction from the second end portion toward the first end portion of the fixed plate portion 10. The first baffle plate portion 61 extends from the front plate portion 50 to the partition plate portion 30 side. The bottom plate portion 40 has a first hole 42. A wall material construction structure Y1 according to the present invention includes such a ventilation member X.
Patent AU-2020361608-A1 (AU)
Title: Metabolic profile screening for gestational diabetes
Inventor: KOOS BRIAN J
IPC: G01N33/48
Filed: 2020-10-09
Abstract: Described herein are methods, materials, kits, devices, and assays for use in screening, detection, and treatment of diabetes, including diabetes mellitus and gestational diabetes mellitus (GDM). The amount of a plurality of metabolic markers present in a test sample obtained from the subject is measured, followed by comparing the amount of the metabolic markers present in the test sample to reference levels of the markers; and identifying a subject as susceptible to, or as having, diabetes when the amount of each of the measured markers present in the test sample is increased or decreased relative to the reference levels. Also provided is a method of treating diabetes in a subject when the amount of each of the measured markers present in the test sample is increased or decreased relative to the reference levels.
Patent AU-2020363372-A1 (AU)
Title: Modulating lymphatic vessels in neurological disease
Inventor: KIPNIS JONATHAN
IPC: A61K45/06
Filed: 2020-10-06
Abstract: In some embodiments herein, methods, compositions, and uses for modulating lymphatic vessels of the central nervous system are described. In some embodiments, methods, compositions, or uses for treating, preventing, or ameliorating symptoms of a neurological disease comprise increasing flow via meningeal lymphatic vessels are described.
Patent AU-2020380687-A1 (AU)
Title: Exercise apparatus
Inventor: ELLIOTT DAVID
IPC: A63B21/02
Filed: 2020-11-04
Abstract: An exercise apparatus comprises a movable carriage having a generally flat top surface, the carriage being movably mounted on parallel track members of a frame having a head end and a foot end, the carriage having a pair of shoulder stops mounted thereto and plurality of elastic members connected between the foot end and the carriage to elastically bias the carriage toward the foot end of the frame. The apparatus has a movable spring anchor bar and carriage stop assembly comprising an anchor bar with at least one elongated stop member arranged perpendicular to and secured to the anchor bar, the stop member having a carriage stop surface located towards the end of the stop member remote from the anchor bar and the stop member further comprising at least one movable means of engagement with the frame of the exercise apparatus. The anchor bar and stop assembly may easily be moved and readjusted one handed with safety and smooth operation.
Patent AU-2020406866-A1 (AU)
Title: A cleaner head for a cleaning appliance
Inventor: BENNETT SAMUEL
IPC: A47L11/30
Filed: 2020-12-18
Abstract: A cleaner head for a cleaning appliance, including: a housing having a front side, a rear side, and first and second sides which extend between the front side and the rear side, the housing further including a floor facing surface which extends between the front side, rear side and first and second sides which, in use, faces a surface to be cleaned; and a floor engaging device which is connected to the floor facing surface of the housing and which extends laterally between the first and second sides of the housing, said floor engaging device including: a first portion for absorbing liquid from a surface to be cleaned; and a second portion positioned closer to either a front side or a rear side of the housing, said second portion being relatively stiff compared to the first portion.
Patent AU-2020415851-A1 (AU)
Title: Motor splitting or assembling apparatus, motor splitting method, and motor assembling method
Inventor: HOU NAN
IPC: H02K15/02
Filed: 2020-06-09
Abstract: The present application relates to a motor splitting or assembling apparatus, a motor splitting method, and a motor assembling method. The motor splitting or assembling apparatus comprises: a fitting apparatus, used for separating or coaxially fitting a first revolving body and a second revolving body of the motor; a first dividing apparatus, used for fixing the first revolving body, the first dividing apparatus comprising at least two detachably connected first separable portions, and the first dividing apparatus circumferentially splits the first revolving body by dividing the first separable portions or circumferentially assembles split segments of the first revolving body by assembling the first separable portions; and a second dividing apparatus, used for fixing the second revolving body, the second dividing apparatus comprising at least two detachably connected second separable portions, and the second dividing apparatus circumferentially splits the second revolving body by dividing the second separable portions or circumferentially assembles split segments of the second revolving body by assembling the second separable portions. The present application solves the problems in which the road transportation of motors exceeds limits and the transportation costs are high.