baber/WOPTO huggingface dataset:
Patent DK-167684-B1 (DK)
Inventor: BALDWIN JOHN J
IPC: C07D495/04
Filed: 1988-06-24
Granted: 1993-12-06
Abstract: Aromatic sulfonamides with a saturated heterocycle fused thereto are carbonic anhydrase inhibitors useful in the treatment of elevated intraocular pressure.
Patent DK-167837-B1 (DK)
Title: Nasal device
Inventor: PETRUSON BJOERN
IPC: A61F/
Filed: 1988-07-04
Granted: 1993-12-27
Abstract: Devices for improving nasal breathing and to nasal drug delivery devices having two end portions of a resilient material in the form of relatively thin tabs, preferably having a gentle curvature, interconnected by a resilient member. Upon bending of the connecting member, the two end tabs can be positioned in respective nostrils where they will be biased outwardly against the nasal side walls, the outward biasing force being sufficient to locate the device in the nose and to dilate the anterior part of each nasal cavity by an amount to improve nasal breathing. No part of the device is grippingly engaged with the septum and a substantial free passage for air flow remains between the septum wall and the nasal side wall-contacting face of each end tab.
Patent FI-102356-B1 (FI)
Inventor: GREENFIELD ROBERT S
IPC: A61K31/70
Filed: 1990-05-14
Granted: 1998-11-30
Abstract: The present invention relates to novel conjugates, methods for their production, pharmaceutical compositions and methods for delivering cytotoxic anthracyclines to a selected population of cells desired to be eliminated. The anthracycline conjugates comprise at least one anthracycline molecule linked to a ligand that is reactive with a cell population to be eliminated, the anthracycline having a keto group at the C-13 position, and being attached to the ligand via a linker arm and being bound to that linker arm via an acid-sensitive acylhydrazone bond at the 13-keto position of the anthracycline. The conjugates of the invention are therefore useful in antibody- or ligand-mediated drug delivery systems for the preferential killing of a selected cell population in the treatment of diseases such as cancers and other tumors, non-cytocidal viral or other pathogenic infections, and autoimmune disorders.
Patent IE-48423-B1 (IE)
Title: Lactam terpolymer membranes
IPC: B01D71/52
Filed: 1979-08-08
Abstract: Permselective membranes are provided consisting of lactam-polyol-polyacyl lactam block terpolymers having from 35 to 75% by weight polylactam blocks and 25 to 65% by weight polyalkylene ether blocks. The membranes are particularly suitable as blood dialysis membranes having improved permeability to solutes in the medium range of molecular weights while maintaining acceptable ultrafiltration rates and permeability to low molecular weight solutes. The membranes are provided both as planar films and hollow fibers, have high hydrolytic stability under hot wet sterilization conditions and good mechanical properties under hemodialysis conditions.
Patent IE-47951-B1 (IE)
Title: -acetylenic derivatives of -amino acids
IPC: C07C239/00
Filed: 1978-06-06
Abstract: Novel acetylenic derivatives of alpha -amino acids of the following general structure: wherein Z is beta -methylthioethyl, beta -benzylthioethyl, S-(5'-desoxyadenosin-5' -yl)-S-methylthioethyl, gamma -guanidinopropyl, or RHN(CH2)n-; n is the integer 3 or 4; each R is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 4 carbon atoms and is straight or branched, alkoxycarbonyl wherein the alkoxy moiety has from 1 to 4 carbon atoms and is straight or branched, or wherein R2 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; R1 is hydroxy, a straight or branched alkoxy group of from 1 to 8 carbon atoms, -NR4R5 wherein each of R4 and R5 is hydrogen or a lower alkyl group of from 1 to 4 carbon atoms, or wherein R3 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; and the lactams thereof when Z is RHN(CH2)n- and each R is hydrogen; with the provisos that when Z is beta -benzylthioethyl or S-(5'-desoxyadenosin-5' -yl)-S-methyl-thioethyl, R is hydrogen and R1 is hydroxy, when Z is gamma -guanidinopropyl, R is hydrogen and R1 is hydroxy or a straight or branched lower alkoxy group of from 1 to 8 carbon atoms, and when Z is RHN(CH2)n- both R groups are the same; and pharmaceutically acceptable salts and individual optical isomers thereof.
Patent IE-41377-B1 (IE)
Title: Hypodermic syringe
IPC: A61M5/28
Filed: 1975-06-09
Abstract: 1503585 Hypodermic syringes KONINKLIJKE EMBALLAGE INDUSTRIE VAN LEER BV 13 June 1975 [17 June 1974] 25437/75 Heading A5R A hypodermic syringe comprises a collapsible reservoir 1 of thermoplastic material having a hypodermic needle 3 in fluid communication therewith, the reservoir having walls 4, 5 which are movable towards and away from each other about a point 6 of their connection, the walls 4, 5 being connected to each other and to a third collapsible wall 7 by folding lines defining hinges the reservoir being so treated that the walls 4, 5 are biassed towards each other whereby the infiltration of air into the reservoir is opposed. The reservoir has the shape of a polyhedron having triangular surfaces, four of said surfaces being identical, meeting at point 6 and each having two sides coincident with respective sides of another two of the four surfaces, the third sides of said four surfaces coinciding with the hypotenuses of four identical right angled triangular surfaces forming the third wall 7 of the reservoir the right-angled vertices of which meet at a common point. At least one of said two walls, defined by two of said four identical triangles meeting at point 6, may be divided into four right-angled triangular portions by a folding line. A handle portion 2 may be provided on wall 5. The reservoir is treated by being compressed between hot plates and then allowed to cool so that it tends to resume its compressed position. In a modification, the surfaces of the reservoir may consist of non-isosceles triangles or isosceles non - right - angled triangles.
[GB1503585A]
Patent IE-54099-B1 (IE)
Title: Compositions for topical application to the body
IPC: A61K9/10
Filed: 1982-06-30
Abstract: The invention relates to compositions in the form of a stable "fatty-cream" for topical application to the body which comprise a fatty base, water, at least one hydrophilic non-ionic surfactant and a topically-active therapeutic agent, the composition containing from 50 to 80% (preferably 60-70%) by weight of fatty material(s) and from 1.5 to 5% by weight of surfactant.
Patent IE-54082-B1 (IE)
Title: Ophthalmic irrigating solution
IPC: A61K9/00
Filed: 1982-09-24
Abstract: An ophthalmic irrigating solution useful for irrigating the human eye contains sodium, potassium, magnesium, calcium chloride, and bicarbonate ions as well as dextrose and glutathione in proportions consistent with the osmotic stability and continued metabolism of the endothelial cells. The irrigating solution is prepared by mixing a first basic solution which provides the bicarbonate and a second acidic solution which provides the calcium, magnesium, dextrose and glutathione. The first and second solutions may be stored as stable sterile solutions for extended periods of time and mixed within 24 hours of use.
Patent IE-55732-B1 (IE)
Title: Method and device for selecting one station from a set of stations dialoging with a main station
IPC: H04Q11/04
Filed: 1984-09-26
Abstract: In a method of selecting one station from a set of stations dialoging with a main station, the main station consults groups of stations one at a time, sending a consultation message to each group consulted. Within each group, stations having information to transmit request reservation of a multiplex link time slot connecting the group to the main station. Each station having information to transmit makes this request after a time delay which depends on the address of the station within the group has elapsed since reception of a synchronization signal. When the main station consults a group, only the station which has reserved this multiplex link can send over the link. In a system implementing this method, each group of stations comprises a self-assigned bus and a synchronization signal link. Each station comprises an assignment system connected to the self-assignment bus and to a microproccessor in the station.
[US4713805A]
Patent IE-50607-B1 (IE)
Title: Method of increasing the ductility of articles formed from superplastic alloy
Inventor: GIOVANNI PELLEGRINI
IPC: C22F1/04
Filed: 1980-11-26
Abstract: A method of increasing the ductility of articles formed from a superplastic alloy, the superplastic alloy consisting of aluminium, from 5 to 10% by weight of calcium and at most 1% by weight of impurities, characterized in that these articles, after their superplastic forming, are heated for at least 30 minutes to a temperature of between 400 DEG C. and 600 DEG C.
Patent IE-57635-B1 (IE)
Title: New process for manufacturing derivatives of 17-hydroxy 19-nor progesterone
IPC: C07J7/00
Filed: 1984-10-03
Abstract: The particular object of the present invention is a process which comprises subjecting 3-alkoxy 19-nor pregna 3, 5, 17 (20)-triene to the action of a formylation reactant to obtain the corresponding 6-formylated derivative, to reduce it into a 6-hydroxy methylated derivative which is dehydrated into a methylenic derivative by the action of an acid, to isomerize the latter into a 6-methyl pregna 4, 6, 17 (20)-trienic derivative which is reacted with a bis-hydroxylation reactant to form the corresponding 17 alpha -hydroxy 19-nor progesterone which be may acylated by the action of a functional saturated or unsaturated carboxylic acid derivative. The compounds obtained according to this process find application in therapy as progestogens, or anti-androgen.
Patent IE-53566-B1 (IE)
Title: Intermediate bulk containers
IPC: B65D88/16
Filed: 1982-11-22
Abstract: A flexible intermediate bulk container (1) is provided with a stabilising cradle (2) having supporting members (4a, 4b) spaced to permit the container (1) to sag into space between the supporting members (4a, 4b) to depth substantially equal to the height of the cradle (2).
Patent IE-58283-B1 (IE)
Title: (Alkylsulphonyl) methanesulphonates
IPC: C07C317/04
Filed: 1984-12-05
Abstract: Compounds of the formula: wherein R is methyl or other lower alkyl group; X and X' individually are hydrogen, lower alkyl, aryl, or halogen; and R' is a 2-haloethyl group or other halogenated lower alkyl group are useful in the treatment of neoplastic diseases.
Patent IE-64045-B1 (IE)
Title: Liquid aqueous ophthalmic composition undergoing liquid-gel phase transition
Inventor: CHASTAING GILLES
IPC: A61K31/535
Filed: 1990-10-16
Abstract: The present invention relates to a liquid ophthalmic composition, characterized in that it comprises at least one active principle and a sulphated polysaccharide or sulphated polysaccharide derivative in aqueous solution which undergoes a liquid-gel phase transition on interaction of the said sulphated polysaccharide or one of its derivatives with the proteins of the lachrymal fluid. The present invention also relates to a process for preparing the said composition.
Patent IE-65634-B1 (IE)
Title: New ethanolamine benzoate compounds a process for their preparation and pharmaceutical compositions containing them
Inventor: WIERZBICKI MICHEL
IPC: C07C233/51
Filed: 1992-07-01
Abstract: New ethanolamine benzoate compounds, which can be used as medicaments and which correspond to the formula: <IMAGE> in which R is as defined in the description, in the racemic and enantiomeric forms. These new compounds and their physiologically tolerable salts can be used in therapeutics.
Patent LU-100367-B1 (LU)
Title: Adjustable support for a manhole cover
Inventor: SAUNION MAXIME
IPC: E02D29/14
Filed: 2017-08-11
Granted: 2019-03-19
Abstract: Support (1) for a manhole cover comprising: an inner ring (4); an outer ring (2) arranged coaxially to the inner ring (4); wherein a first circumferential slanted portion (5) is provided in contact to or integral to the inner ring (4), a second circumferential slanted portion (3) is provided in contact to or integral to the outer ring (2), and wherein a circumferential pin (6.1, 6.2, 6.3) is provided between the two slanted portions (3, 5), the circumferential position of the pin (6.1, 6.2, 6.3) with respect to the slanted portions (3, 5) being adjustable to impact the axial position of the inner ring (4) with respect to the outer ring (2). The invention further relates to a tool and to a method for adjusting the relative axial position of the inner ring (4) with respect to the outer ring (2).
Patent LU-100464-B1 (LU)
Title: Process for the removal of heavy metals from liquids
Inventor: STRICKROTH ALAIN
IPC: C01B25/237
Filed: 2017-09-29
Granted: 2019-03-29
Abstract: The present invention discloses a process for the removal of heavy metals from a liquid comprising heavy metals, wherein hydrochloric acid is added to the liquid, wherein the fluid is brought in contact with a mixture comprising between 30%vol. and 60%vol. of an activated carbon catalyst impregnated with sulfur, between 30%vol. and 60%vol. of an activated carbon catalyst impregnated with iron and between 5%vol. and 40%vol. of a filler material, the total of these three ingredients being 100%vol. The fluid is left in contact with the mixture, the heavy metals are absorbed onto the mixture to obtain a fluid with a depleted level of heavy metals, which fluid is then evacuated from the mixture.
Patent LU-101903-B1 (LU)
Title: System and method for storing and accessing private data of Hyperledger Fabric blockchain
Inventor: QI YONG
IPC: H04L9/32
Filed: 2020-06-01
Granted: 2021-01-13
Abstract: The present invention discloses a system for storing and accessing private data of a Hyperledger Fabric blockchain, comprising a client module, an SDK module, a smart contract module and a database module, wherein the client module invokes a private data storage chaincode function through the SDK module, and the smart contract module judges whether a valid chaincode set contains the private data storage chaincode function according to role information in a certificate of the client module and, if the valid chaincode set contains the private data storage chaincode function, encrypts privacy attributes of data and stores the privacy attributes into the database module together with non-privacy attributes; and the client module invokes a private data query chaincode function through the SDK module, and the smart contract module judges whether the valid chaincode set contains the private data query chaincode function according to the role information in the certificate of the client module and, if the valid chaincode set contains the private data query chaincode function, decrypts query results of the database module and returns real data to the client module, or else directly returns cipher text data to the client module The present invention can effectively strengthen the security of personal privacy in Hyperledger Fabric data storage, and is highly confidential and secure.
Patent LU-500133-B1 (LU)
Title: Metallheißteildämmelement zur Verhinderung bzw. Verringerung des Entstehens umwelt- und/oder gesundheitsschädlicher Schwermetallverbindungen
Inventor: LIPP INGRID
IPC: F01N13/14
Filed: 2021-05-06
Granted: 2022-04-12
Abstract: Die vorliegende Erfindung betrifft ein textiles oder teilmetallisches Metallheißteildämmelement (hierein auch als "Dämmelement" bezeichnet) zur Verhinderung bzw. Verringerung des Entstehens umwelt- und/oder gesundheitsschädlicher Schwermetallverbindungen, das in Form als Isoliermatratze, Isolierkissen/Pillow, Isoliermatte, Isoliermanschette, Isolierformteil, Isolierelement, Isolierhaube, Isolierdecke, Glasgewebeformmatte, Isolierkassette, Hardcoverelemente o.ä. ausgebildet ist und zur Wärmeisolierung von Metallheißteilen in einem Temperaturbereich von 20°C bis 750°C verwendet wird.
Patent LU-500160-B1 (LU)
Title: Novel BH3 Mimetic Peptide Compounds Targeting PTP1B, Preparation Method and Application Thereof
Inventor: ZHANG CHUANLIANG
IPC: C07K14/00
Filed: 2021-05-17
Granted: 2021-11-18
Abstract: The present invention provides novel BH3 mimetic peptide compounds targeting PTP1B, a preparation method and an application thereof. A structural formula of the BH3 mimetic peptide compounds is shown as follows: R1-PUMABH3-R2; R1-BADBH3-R2; R1-BIDBH3-R2; R1-NOXABH3-R2; R1-BAKBH3-R2; R1-BIKBH3-R2; R1-BMFBH3-R2; R1-HRKBH3-R2; All amino acids in structures of the BH3 mimetic peptide compounds are natural amino acids, an amino terminal of a peptide chain is modified with an R1 group through an amide bond, R1 is carboxylic acid or dicarboxylic acid, and R2 is OH or NH2. Such mimetic peptide compounds are derived from core regions of BH3 domains of Bcl-2 anti-apoptotic proteins, and prepared by solid-phase peptide synthesis. The present invention demonstrates that the BH3 mimetic peptide compounds can significantly inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), and have potential application value in the development of drugs for related diseases targeting PTP1B, such as diabetes, cancer and Alzheimer's disease.
Patent LU-500817-B1 (LU)
Title: Preparation method of one time rising for frozen minced fish
Inventor: HUANG JIANLIAN
IPC: A23L17/00
Filed: 2021-11-03
Granted: 2022-05-03
Abstract: This invention discloses preparation method of one time rising frozen minced fish, which comprises the following steps: cleaning and collecting meat from marine fish, then immediately putting the obtained fish meat into rinsing liquid that is precooled to 4±1?, rinsing the meat with stirring motion for 5-10 min, and using ultrasonic to rinsing with stirring motion for another 20-25 min, and then dehydrating the meat. The dehydrated fish meat is put into chopping machine, and adding water in the chopping process until the water content of the obtained minced fish is adjusted to be 78-80%, freezing the processed minced fish, in order to obtain the frozen minced fish. This invention adopts ultrasonic-assisted rinsing to ensure rinsing effect, impurities such as water-soluble proteins in fish meat can be effectively removed, and wastes generated in the production process of frozen minced fish can be effectively reduced.
Patent LU-503909-B1 (LU)
Title: Environment-friendly coating for constructions and preparation method thereof
Inventor: ZHANG CHEN
IPC: C09D5/00
Filed: 2023-04-11
Granted: 2023-10-16
Abstract: Disclosed are an environment-friendly coating for constructions and a preparation method thereof, and they relate to the technical field of coatings. The environment-friendly coating for constructions includes the following raw materials: modified epoxy resin materials, pigments, fillers, gelatin, propylene carbonate, benzyl alcohol, modified acrylate leveling agent, hydroxypropyl methylcellulose and water. The environmental-friendly coating for constructions prepared by mixing the above raw materials in proportion, has a VOC content of 15 g/L, an impact resistance of 63 cm, and an aging resistance of 2523 h. After the coating is soaked in 3 percent NaCl solution for 7 days, no change has occurred, indicating good salt water resistance of the coating. The environmental-friendly coating for constructions has low volatile organic content, excellent impact resistance, aging resistance, and salt water resistance, and has a wide application prospect.
Patent NO-302999-B1 (NO)
Inventor: BOWALD STAFFAN FOLKE
IPC: A61F2/02
Filed: 1990-02-23
Abstract: Polyhydroxybutyric acid polymers or copolymers of hydroxybutyric acid and hydroxyvaleric acid may be used for preparing a porous, bioresorbable flexible sheet for tissue separation and stimulation of tissue regeneration at healing processes in injured soft tissue in mammals including man. The sheet has a pore size permitting passage of water and salts through the sheet but which locks out cells and other tissue particles. Processes for preparation of the material and are also described.
Patent NO-301851-B1 (NO)
Inventor: UNEWISSE HEINZ
IPC: F16L37/02
Filed: 1991-04-11
Abstract: The invention relates to a process for manufacturing a fixed, sealed pipe connection between a smooth pipe end and a press fitting which surrounds said end, the press fitting being compressed in a force-fitting and positively locking manner with the inserted pipe end, by means of a compression tool which is placed on it. The invention is characterised in that, once the compression tool is placed in position, the pipe, which has already manually been inserted into the press fitting, and the press fitting, which has been pushed onto the pipe end, are forcibly subjected to a variable force, acting axially, by means of a device arranged on the compression tool, and the closing movement of the jaws for the compression of the press fitting cannot be released until this force assumes a value which is greater than a predetermined adjustable threshold value. 
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Patent NO-308585-B1 (NO)
Inventor: BOLOGNA WILLIAM JOSEPH
IPC: A61F13/45
Filed: 1996-03-14
Abstract: The present invention teaches that relatively low levels of serum progesterone, 1 to 6 ng/ml, may be used to prevent endometrial cancer. The vaginal delivery of progesterone using a cross-linked polycarboxylic polymer produces this low serum progesterone level while also providing the full secretory transformation of the endometrium, indicating the efficacy of the progesterone. Such low levels of serum progesterone will decrease the risk of breast cancer experienced by women undergoing hormone replacement therapy ("HRT") and minimize the potential of other undesirable progesterone associated side effects.
Patent NO-314077-B1 (NO)
Title: Flaskeholder
Inventor: SHORTER EDDIE
IPC: B65D71/70
Filed: 1997-03-10
Abstract: En flaskeholder (1) som en gjenbrukbar innpakning for glassflasker. Den har flere fordypninger (8) anordnet med jevne mellomrom for å oppta glassflasker (2) med i det vesentlige den samme størrelse stående på ett plan, og er kjennetegnet ved at de horisontale utvendige dimensjoner av dens stående areal svarer til i det minste omtrent lastarealet for en delpall (7), og dens høyde er betydelig mindre enn halvparten av høyden av flaskene (2) som skal innsettes. Dette gjør det mulig å stable de tomme flaskeholdere på en rombesparende måte. En første flaskeholder tjener til å oppta et første lag av flasker (2). En andre flaskeholder av den samme type er anbrakt på det første lag av flasker som er innsatt og tjener til å oppta et andre lag av flasker. På denne måten blir vekten av hver flaske i det andre lag overført direkte til den andre flaskeholder og direkte til de respektive munninger eller hoder av flaskene i det første lag.
Patent NO-308590-B1 (NO)
Inventor: ABRAHAMSSON CLAS
IPC: B27L7/00
Filed: 1997-03-19
Abstract: PCT No. PCT/SE95/01104 Sec. 371 Date Mar. 11, 1997 Sec. 102(e) Date Mar. 11, 1997 PCT Filed Sep. 25, 1995 PCT Pub. No. WO96/09922 PCT Pub. Date Apr. 4, 1996The present invention relates to a hand-operated wood-splitter with striking weight (1) movable along a rod (2) connected at its lower end to an axe or splitting wedge (5). The invention is characterized in that the rod (2) for the striking weight (1) is provided at its upper end with a stop nut or other stop means (12). The axe, etc. is secured to a swinging arm (8) movable along a second rod (7) and rotatable around this. This latter rod is secured to a stamp (10) or a stand. At the lower end of the rod for the striking weight is a nut or ring which is movable to a limited extent in vertical direction in order to reduce the stresses.