baber/WOPTO huggingface dataset:
Patent WO-2020069339-A1 (WO)
Title: Mutant reverse tetracycline transactivators for expression of genes
Inventor: SINCLAIR DAVID
IPC: C12N15/63
Filed: 2019-09-27
Abstract: Provided herein are mutant reverse tetracycline transactivator (rtTA) proteins and engineered nucleic acids ( e.g ., viral vectors, including lentiviral vectors, adenoviral vectors, AAV vectors, herpes viral vectors, and retroviral vectors, and non-viral vectors, including RNA and plasmid DNA) that encode a mutant rtTA that are useful, for example, in regulating gene expression, inducing cellular reprogramming, tissue repair, tissue regeneration, organ regeneration, reversing aging, treating a disease ( e.g ., acute injuries, neurodegenerative disease, chronic diseases, proliferative diseases, cardiovascular diseases, genetic diseases, inflammatory diseases, autoimmunue diseases, neurological diseases, hematological diseases, painful conditions, psychiatric disorders, metabolic disorders, cancers, aging, age-related diseases, and diseases affecting any tissue in a subject), or any combination thereof. Also provided herein are recombinant viruses ( e.g ., lentiviruses, adenoviruses, alphaviruses, vaccinia viruses, retroviruses, herpes viruses, or A A Vs) comprising the engineered nucleic acids and methods of regulating ( e.g. , inhibiting or inducing) cellular reprogramming, tissue repair, tissue regeneration, or any combination thereof by administering an engineered nucleic acid or recombinant virus comprising the same in a cell, tissue or subject ( e.g ., a cell or tissue of a subject with a condition, which includes any disease ( e.g ., ocular disease), aging, neurodegenerative diseases, cancer, and age-related diseases) comprising administering a mutant rtTA and an inducible nucleic acid ( e.g. , an engineered nucleic acid, including an expression vector) encoding a transgene.
Patent WO-2020076963-A1 (WO)
Inventor: KAAR JOEL L
IPC: A61K47/50
Filed: 2019-10-09
Abstract: The invention provides methods and systems by which enzymes can be modified to improve solubility, catalytic activity, recoverability, and recyclability. The enzyme may be modified with a thermosensitive copolymer to form an enzyme-polymer conjugate that exhibits upper critical solution temperature (UCST) and/or lower critical solution temperature (LCST)-type behavior in an organic solvent, ionic liquid, or other solvent. Methods and systems of the invention facilitate the use of enzymes as biocatalysts in solvents.
Patent WO-2020131206-A1 (WO)
Title: Methods for forming structures for mram applications
Inventor: AHN JAESOO
IPC: H01L43/02
Filed: 2019-10-18
Abstract: Embodiments of the disclosure provide methods and apparatus for fabricating magnetic tunnel junction (MTJ) structures on a substrate for MRAM applications, particularly for spin-orbit-torque magnetic random access memory (SOT MRAM) applications. In one embodiment, a magnetic tunnel junction (MTJ) device structure includes a magnetic tunnel junction (MTJ) pillar structure disposed on a substrate, and a gap surrounding the MTJ pillar structure. In yet another embodiment, a magnetic tunnel junction (MTJ) device structure includes a spacer layer surrounding a patterned reference layer and a tunneling barrier layer disposed on a patterned free layer, and a gap surrounding the patterned free layer.
Patent WO-2020092297-A1 (WO)
Title: Devices and methods for treatment of body lumens
Inventor: DUVAL GEORGE
IPC: A61B5/00
Filed: 2019-10-29
Abstract: A method for performing a medical procedure may comprise advancing a first device through a first body lumen. A distal portion of the first device may include a magnet. The method may further comprise advancing a second device through a second body lumen. The second device may include a magnetic field sensor. The method may further comprise receiving a signal from the magnetic field sensor. The signal may be indicative of a magnetic field measured by the magnetic field sensor. The method may further comprise, if the received signal matches a magnetic field of the magnet, identifying a position of the magnet.
Patent WO-2020117992-A1 (WO)
Title: Improved vector systems for cas protein and sgrna delivery, and uses therefor
Inventor: HAINING WILLIAM
IPC: C12N15/87
Filed: 2019-12-04
Abstract: The present disclosure provides vectors, methods and kits for for delivery and stable expression of CRISPR/Cas components capable of inducing genetic modification of cells, followed by recombinase-mediated excision of some or all of these components after the cells have been successfully genetically modified. The disclosed vectors and methods provide for reduced immunogenic effects arising from one or more CRISPR/Cas components. The disclosed vectors comprise coding sequences that encode a Cas protein, detectable markers and a guide RNA. The disclosed vectors provide for the subsequent genomic excision of the CRISPR/Cas components after successful genetic modification, as mediated by recombinase recognition of recombination sites flanking one or more of the disclosed coding sequences. The present disclosure further provides methods of generating a population of genetically modified tumor cells for screening a candidate target gene for cancer immunotherapy.
Patent WO-2020123402-A1 (WO)
Title: Cartographie d'anomalies de champ à l'aide d'images numériques et de modèles d'apprentissage automatique
Inventor: PESHLOV BOYAN
IPC: G01N33/00
Filed: 2019-12-09
Abstract: L'invention concerne un procédé mis en œuvre par ordinateur permettant de générer une carte améliorée d'anomalies de champ à l'aide d'images numériques et de modèles d'apprentissage automatique. Selon un mode de réalisation, un procédé consiste : à obtenir un fichier de forme définissant des limites d'une parcelle agricole et des limites du champ contenant la parcelle ; à obtenir une pluralité d'images de parcelle ; à étalonner et à prétraiter la pluralité d'images de parcelle afin de créer une carte de parcelle de la parcelle agricole à un niveau de parcelle ; en fonction de la carte de parcelle , à générer une grille de parcelle ; en fonction de la grille de parcelle et de la carte de parcelle, à générer une pluralité de pavés de parcelle ; en fonction de la pluralité de pavés de parcelle, à générer, à l'aide d'un modèle d'apprentissage automatique et d'une pluralité de classificateurs d'image correspondant à une ou plusieurs anomalies, un ensemble d'images de parcelle classées représentant au moins une anomalie ; en fonction de l'ensemble d'images de parcelle classées, à générer une carte d'anomalies de parcelle pour la parcelle agricole.
Patent WO-2021112886-A1 (WO)
Title: Lwd formation tester with retractable latch for wireline
Inventor: JONES CHRISTOPHER MICHAEL
IPC: E21B49/08
Filed: 2019-12-10
Abstract: A method comprising: without removing a BHA from a wellbore of a well extending into a formation, extending, into an interior flow bore of the BHA, a first component of a wet latch assembly to provide an extended first component of the wet latch assembly; conveying downhole via a wireline cable, from a surface through an interior flow bore provided by a drill string, a second component of the wet latch assembly, and coupling the second component of the wet latch assembly with the extended first component of the wet latch assembly such that an electrical connection is established between the first component and the second component and between the BHA and the surface via the wireline cable; and testing the formation with a formation tester of the BHA, while providing power and/or data telemetry for the formation tester via the wet latch assembly and the wireline cable.
Patent WO-2020132627-A1 (WO)
Title: Systems and methods for object dimensioning based on partial visual information
Inventor: DAL MUTTO CARLO
IPC: G06T17/00
Filed: 2019-12-20
Abstract: A method for estimating tightly enclosing bounding boxes by a computing system includes: controlling a scanning system including one or more depth cameras to capture visual information of the scene including one or more objects; detecting the one or more objects of the scene based on the visual information; singulating each the one or more objects from the frame of the scene to generate one or more 3D models corresponding to the one or more objects, the one or more 3D models including a partial 3D model of a corresponding one of the one or more objects; extrapolating a more complete 3D model of the corresponding one of the one or more objects based on the partial 3D model; and estimating a tightly enclosing bounding box of the corresponding one of the one or more objects based on the more complete 3D model.
Patent WO-2020142447-A1 (WO)
Title: Procédés et appareil de codage vidéo destinés à une prédiction de triangle
Inventor: WANG XIANGLIN
IPC: H04N19/137
Filed: 2019-12-30
Abstract: L'invention concerne un procédé de codage vidéo. Le procédé consiste : à partitionner des images vidéo en une pluralité d'unités de codage (CU), au moins une de ces dernières étant en outre divisée en deux unités de prédiction (PU), dont au moins une PU de forme triangulaire présentant une orientation de partitionnement parmi : du coin supérieur-gauche au coin inférieur-droit, et du coin supérieur-droit au coin inférieur-gauche ; à construire une liste de candidats de vecteur de mouvement de prédiction unique ; à déterminer si une CU actuelle est codée en tant que mode de prédiction de triangle en fonction d'informations codées ; à signaler un indicateur d'orientation de partition indiquant l'orientation de partitionnement ; et à signaler des valeurs d'indice qui indiquent des entrées sélectionnées dans la liste de candidats de vecteur de mouvement de prédiction unique construite.
Patent WO-2020146638-A1 (WO)
Inventor: XIONG GANG
IPC: H04L5/00
Filed: 2020-01-09
Abstract: For single carrier based waveform, Discrete Fourier Transform-spread-OFDM (DFT-s-OFDM) and single carrier with a frequency domain equalizer (SC-FDE) can be considered for both DL and UL. For OFDM based transmission scheme including DFT-s-OFDM, a cyclic prefix (CP) is inserted at the beginning of each block, where the last data symbols in a block is repeated as the CP. Typically, the length of CP exceeds the maximum expected delay spread in order to overcome the inter-symbol interference (ISI). For SC-FDE transmission scheme, a known sequence (guard interval (GI), unique word (UW), etc.) can be inserted at both the beginning and end of one block. Further, a linear equalizer in the frequency domain can be employed to reduce the receiver complexity. Compared to OFDM, SC-FDE transmission scheme can reduce Peak to Average Power Ratio (PAPR) and thus allow the use of less costly power amplifier.
Patent WO-2020154160-A1 (WO)
Inventor: HAYES ROBERT ANDREW
IPC: C08G65/00
Filed: 2020-01-16
Abstract: L'invention concerne une composition comprenant un composé de formule générale (I) : F – [CF2]n – (O[CF2]n)m –( L )p – SH (formule (I)) Chaque n a indépendamment une valeur de 2 à 4, m a une valeur de 3 à 30, p a une valeur de 0 ou 1 et L représente un coupleur ayant la formule Oq(CF2)r(CH2)s, q ayant une valeur de 0 ou de 1, r ayant une valeur de 0 à 4 et s ayant une valeur de 0 à 4.
Patent WO-2020176179-A1 (WO)
Inventor: MCDUFF DANIEL J
IPC: G10L13/027
Filed: 2020-01-23
Abstract: A conversational agent that is implemented as a voice-only agent or embodied with a face may match the speech and facial expressions of a user. Linguistic style-matching by the conversational agent may be implemented by identifying prosodic characteristics of the users speech and synthesizing speech for the virtual agent with the same or similar characteristics. The facial expressions of the user can be identified and mimicked by the face of an embodied conversational agent. Utterances by the virtual agent may be based on a combination of predetermined scripted responses and open-ended responses generated by machine learning techniques. A conversational agent that aligns with the conversational style and facial expressions of the user may be perceived as more trustworthy, easier to understand, and create a more natural human-machine interaction.
Patent WO-2021154304-A1 (WO)
Title: Contact pads-based chassis type detection
Inventor: LIN HSIN-TSO
IPC: H05K7/00
Filed: 2020-01-31
Abstract: In one example, a computing device may include a circuit board having a contact pad disposed at an edge of the circuit board, and a chassis in which the circuit board is installed. The chassis may include a circuit board holder to engage the edge of the circuit board to retain the circuit board in a defined position relative to the chassis. The circuit board holder may be grounded. Further, the computing device may include a controller to receive a signal from the contact pad, the signal indicative of a presence of the circuit board holder contacting the contact pad. Furthermore, the controller may detect a form factor type of the chassis based on the received signal.
Patent WO-2020172053-A1 (WO)
Title: Système et procédé d'alignement électrostatique et d'assemblage de surface de cristaux photoniques pour une exposition de couleur dynamique
Inventor: YIN YADONG
IPC: G02B1/02
Filed: 2020-02-14
Abstract: L'invention concerne un système et un procédé d'alignement électrostatique et d'assemblage de surface de cristaux photoniques pour une exposition de couleur dynamique. Le procédé comprend les étapes consistant à : disperser une pluralité de chaînes de cristaux photoniques dans une solution ; placer la solution de la pluralité de chaînes de cristaux photoniques dans un récipient ; et assembler et aligner la pluralité de chaînes de cristaux photoniques dans la solution par une accumulation de charge locale sur une surface du récipient pour présenter une couleur.
Patent WO-2020172113-A1 (WO)
Inventor: HEBER-KATZ ELLEN
IPC: A61B17/03
Filed: 2020-02-18
Abstract: A composition comprising a wound-closure material physically or chemically associated with an agent that reduces scarring and improves the integrity of skin and underlying tissue in a mammalian subject. Methods for reducing or eliminating scarring or improving mammalian skin integrity comprise closing a wound with a composition, such as a suture material associated with a PHD inhibitor molecule, e.g., 1,4-DPCA.
Patent WO-2020186173-A1 (WO)
Title: Gas fermentation for the production of protein-based bioplastics
Inventor: ALLEN WYATT
IPC: C08L89/00
Filed: 2020-03-13
Abstract: The invention provides methods of producing protein-based bioplastics and protein-based biofilms by culturing a microorganism to produce microbial biomass. In particular, the invention relates to protein-based bioplastics and protein-based biofilms produced by fermentation of a gaseous substrate comprising one or more of CO, CO2, and H2, especially by a Gram-positive, anaerobic, and/or Clostridium microorganism.
Patent WO-2020191195-A1 (WO)
Inventor: RABINOWITZ MATTHEW
IPC: A61B5/00
Filed: 2020-03-19
Abstract: Provided are methods for outputting a non-Mendelian risk score, comprising: receiving from a first dataset (i) genotype data for a subject and (ii) genotype data and phenotype data for one or more blood relatives of a subject having a gene of interest; receiving from a second dataset genotype population data and phenotype population data, wherein the population comprises two or more blood relatives; training a model on the first and second datasets to determine a genetic risk in the subject associated with one or more non-Mendelian gene of interest; and outputting a phenotypic risk score for the subject. Also provided are systems and non-transitory machine-readable media for outputting a polygenic risk score for a subject.
Patent WO-2020191352-A1 (WO)
Inventor: TALARICO SALVATORE
IPC: H04L5/00
Filed: 2020-03-20
Abstract: Some embodiments of this disclosure include systems, apparatuses, methods, and computer-readable media for use in a wireless network for time-domain resource allocation for configured grant transmissions in New Radio (NR) systems. For example, some embodiments are directed to an electronic device including radio front end circuitry and processor circuitry coupled to the radio front end circuitry. The processor circuitry can be configured to generate a radio resource control (RRC) signal including a bitmap for configuring time-domain resources for configured grant (CG) operation. The processor circuitry can be further configured to transmit, using the radio front end circuitry, the RRC signal to a user equipment (UE) to configure the time-domain resources. The bitmap comprises a plurality of resource units and wherein each resource unit in the plurality of resource units corresponds to a symbol, a slot, a subframe, or a radio frame.
Patent WO-2020226764-A1 (WO)
Title: Execution of application in a container within a scope of user-granted permission
Inventor: MURDOCH BRANDON
IPC: G06F21/62
Filed: 2020-03-24
Abstract: Executing an application in a container within a scope of user-granted permission in a decentralized network that implements a distributed edger. Receiving a request from an entity for using data stored in a data storage that is associated with a DID as one or more inputs of an application associated with the entity to generate one or more results. One or more characteristics of the application is identified. Based on the identified characteristics, a scope of permission to use the requested data is determined. Next, the scope of permission is granted to a container where the application is stored or is to be stored. The application is then executed in the container using the data within the granted scope of permission as input to generate one or more results.
Patent WO-2020205360-A1 (WO)
Title: Process for manufacturing multi-layer substrates comprising sandwich layers and polyethylene
Inventor: DANI NIKHIL
IPC: A47L13/16
Filed: 2020-03-25
Abstract: Methods for forming multi-layer substrates comprising top and bottom surface layers and a melt softened thermoplastic material layer between the exterior surface layers, where the thermoplastic material comprises polyethylene or has a tan delta value of 0.2 to 0.4 within the temperature range of 100°F-350°F. The 3 (or more) layers are assembled, and heated, melt softening the thermoplastic material, causing bonding of the thermoplastic layer to the exterior surface layers. A cleaning composition may finally be loaded onto the multi-layer substrate, where a fluid pathway through the melted thermoplastic material allows the cleaning composition to travel between the surface layers. Adhesion between the surface layers and the thermoplastic layer is provided by the thermoplastic material itself, which bonds to groups of fibers in the surface layers. The process does not require chemical adhesives, any processing water, drying, or the like, so as to be possible with low capital investment.
Patent WO-2020247098-A1 (WO)
Title: Digital barcode reader
Inventor: ZHAO WANCHENG
IPC: G06K7/10
Filed: 2020-04-22
Abstract: A barcode reader assembly for capturing at least one object appearing in a field of view (FOV) is provided that includes a reader, a gear member, and a stand. The reader includes a reader enclosure having a top portion and a bottom portion which forms a base. The gear member includes a gear member coupling portion, and is mechanically coupled to the bottom portion of the reader enclosure. The stand includes a platform and a platform coupling portion. The gear member coupling portion is mechanically coupled to the platform coupling portion such that the reader is rotatable relative to the stand.
Patent WO-2020219979-A1 (WO)
Inventor: TAYLOR KYLE PATRICK
IPC: A61M1/00
Filed: 2020-04-24
Abstract: A treatment device for treatment of overactive bladder conditions operates to suction to grasp and conform a mucosal tissue of the bladder wall to a portion of the tissue treatment device, and deliver energy to non-superficial target tissue at a substantially uniform depth from the mucosal tissue. The tissue treatment device incorporates multiple instruments for different functions needed to treat overactive bladder conditions. The tissue treatment device provides simplified interfaces and mechanisms for operating each of the multiple instruments in a controlled manner. Further, the tissue treatment device is configured to have a low and smooth profile that permits the tissue treatment device to be used without a tubular sheath.
Patent WO-2020226920-A1 (WO)
Inventor: FU HAO
IPC: G06F16/332
Filed: 2020-04-27
Abstract: The present disclosure provides a method for generating a content containing a specific word and an electronic device, the method includes: an electronic device pre-generating a first content while interacting with a user; for each specific word in a specific word stock: embedding the specific word into the first content to obtain a corresponding second content, and obtaining a result of evaluating, by using a statistical model and a neural network model, the second content based on an explanatory word, included in the specific word stock, corresponding to the specific word; and outputting at least one of a plurality of the second contents according to the evaluation results, wherein the specific word stock is generated and periodically updated based on a specific corpus using the neural network model.
Patent WO-2020220037-A1 (WO)
Title: Procédés et appareils de codage vidéo à prédiction triangulaire
Inventor: WANG XIANGLIN
IPC: H04N19/423
Filed: 2020-04-27
Abstract: La présente invention concerne des procédés et des appareils de codage vidéo. Le procédé consiste à : partitionner des images vidéo en une pluralité d'unités de codage (CU), dont au moins une est en outre partitionnée en deux unités de prédiction (PU) comprenant au moins une PU de forme géométrique ; obtenir une première liste de fusion comprenant une pluralité de candidats, comprenant chacun un ou plusieurs vecteurs de mouvement ; et obtenir une liste de fusion uniprédictionnelle pour la PU de forme géométrique par sélection du ou des vecteurs de mouvement directement à partir de la première liste de fusion.
Patent WO-2020236447-A1 (WO)
Inventor: IVANOV VIACHESLAV VIACHESLAVOVICH
IPC: B23K103/00
Filed: 2020-05-11
Abstract: A method for processing a transparent workpiece that includes directing a laser beam the transparent workpiece. The laser beam incident to the impingement surface has an oblong angular spectrum and portion of the laser beam directed into the transparent workpiece is a laser beam focal line and generates an induced absorption to produce a defect within the transparent workpiece. The laser beam focal line includes a wavelength λ, a spot size  w 
   o   , a Rayleigh range  Z 
   R   
   that is greater than  F 
   D   
   (I) where  F 
   D   
   is a dimensionless divergence factor comprising a value of 10 or greater, and an internal beam angle of greater than 10° relative to a plane orthogonal to an impingement surface at an impingement location, such that the defect has a defect angle within the transparent workpiece of greater than 10° relative to a plane orthogonal to the impingement surface at the impingement location.
Patent WO-2020236835-A1 (WO)
Inventor: APPEL CRAIG S
IPC: H03K19/003
Filed: 2020-05-19
Abstract: Embodiments provide for a tunable driving circuit (180) by monitoring (160) a frequency of a ring oscillator (140) of an electrical integrated circuit (110) connected to an optical modulator (121) to determine operational characteristics of the electrical integrated circuit (110); setting, based on the operational characteristics, a driving voltage for a plurality of tunable inverters (fig. 1: 182, fig. 7: 730, 760) and a plurality of fixed gain inverters (fig. 1. 182, fig. 7: 740, 750) that control the optical modulator (121), wherein each tunable inverter of the plurality of tunable inverters (fig. 7: 730, 760) is connected in parallel with a corresponding fixed gain inverter (fig. 7: 740, 750) of the plurality of fixed gain inverters on one of a first arm (fig. 7: 610A) and a second arm (fig. 7: 610B) connected to the optical modulator (121); and setting an amplification strength for the plurality of tunable inverters based on the operational characteristics.