baber/WOPTO huggingface dataset:
Patent NZ-503397-A (NZ)
Title: 3-amino-3-arylpropan-1-ol derivatives, and their preparation and use as a medicament in the treatment of chronic pain and other illnesses
Inventor: SUNDERMANN BERND
IPC: C07C219/24
Filed: 2000-03-14
Abstract: 3-Amino-3-arylpropan-1-ol derivatives of the formula I, wherein: R1, and R2 individually denote C1-6 alkyl, or R1 and R2 together form a (CH2)2-6 ring, which can be benzo-fused or phenyl-substituted R3 denotes H or methyl R4, and R5 independently denote C1-6 alkyl, C3-6cycloalkyl, phenyl, benzyl or phenethyl, or R4 and R5 together form a (CH2)3-6 or CH2CH2OCH2CH2 ring A denotes an aryl radical which optionally contains heteroatoms in the ring system and/or can be substituted X denotes a substituted benzyl of formula XI or a substituted benzoyl of formula XII, wherein: R12 to R14 independently denote H, F, Cl, Br, CHF2, CF3, OR11, SR11, OCF3, SO2CH3, SO2CF3, C1-6 alkyl, phenyl, CN, CooR11, or NO2, where R11 denotes H. C1-6 alkyl, phenyl, benzyl or phenethyl. Also disclosed is the use of the above compound in medicaments for combating pain, including neuropathic and chronic pain, for treating cardiovascular disease, urinary incontinence, diarrhoea, pruritus, alcohol dependency, drug dependency, inflammation and also for a medicament having a local anaesthetic action, an antiemetic action, an antiarrhythic action and a nootropic action.
Patent NZ-506528-A (NZ)
Title: Subcutaneous HBED administration to treat iron overload disorders
Inventor: BERGERON RAYMOND J
IPC: A61K31/195
Filed: 1999-02-03
Abstract: The use of N,N'-bis(2- hydroxybenzyl) ethylenediamine-N, N'-diacetic acid (HBED) in iron chelating therapy is disclosed.  In particular, the subcutaneous use of HBED for treating mammals with a disease treatable by an iron chelator such as iron overload, especially transfusional iron overload. Such diseases include malaria, cancer, HIV infections, inflammatory bowel disease, host v graft rejection, graft v host rejection, reperfusion injury, neurological disorders, and iron overload.  The disease state in which the use is most useful is "iron overload."  It is characterised by greater than normal focal or generalised deposition of iron within body tissues (haemosiderosis).
Patent NZ-510473-A (NZ)
Title: Tag / Label with retention means for attaching to planter's pot or for insertion into soil
Inventor: MILLS KEITH WILLIAMS
IPC: G09F3/16
Filed: 2001-03-09
Abstract: A self supporting tag (1) formed from a sheet material with a retention region having a cut out (2) that defines a retention edge which, by virtue of cuts extending from such a cut out or by virtue of an extension of the cut out itself, is a distal edge (9) of a flap.
Patent NZ-512804-A (NZ)
Title: Potassium salt of (S)-omeprazole form B
Inventor: NILSSON MATHS
IPC: A61K31/4439
Filed: 2000-01-18
Abstract: Potassium salt of (S)-omeprazole form B is prepared by converting (S)-omeprazole into the corresponding potassium salt in toluene or dichloromethane by treatment with a potassium source, such as potassium hydroxide or potassium methylate, followed by isolation of the formed salt.  This salt can be used in the manufacture of pharmaceutical formulation for i.v. administration for treating gastrointestinal disorders.  (S)-omeprazole is obtained by oxidizing 5-methoxy-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole, with an oxidizing agent and a chiral titanium complex, optionally in the presence of a base in an organic solvent, such as toluene or dichloromethane.
Patent NZ-515625-A (NZ)
Title: Projectile for delivery of a tranquilliser
Inventor: BRYDGES-PRICE RICHARD IAN
IPC: F42B12/54
Filed: 2000-05-23
Abstract: A projectile mainly for drug delivery comprises a tubular body casing 1 which defines a cavity 2 for containment of a tranquillising drug. The casing has an end plug 3 which coaxially supports a hollow needle 4 projecting forward through an ogival nose cap 5. Located around the needle 4 towards the tip of the nose cap 5 is a gas producing detonator 7 fired by an impact fuse 8. Attached to the detonator 7 and the needle 4 is the neck 9 of an inflatable bag 10 of which an opposed end 11 is attached to the plug 3. The rear end of the cavity 2 has a piston 12 the rear end of which communicates through concentric passageways 13 and ducts 14 with the interior of the bag 10. The nose cap 5 is of a readily breakable plastics material or designed to assist retardation. An impact absorbing material may be contained in the nose cap. On impact with a target the detonator 7 is driven back along the needle and fired via the fuse 8 to thus inflate the bag 10 rapidly. The bag 10 expands and prevents excess penetration whilst spreading the impact energy over a wide area. The bag inflation gas bleeds through ducts 14 and passageways 13 to drive piston 12 forward thus delivering the drug through the needle 6.
Patent NZ-518506-A (NZ)
Title: Overload protection device for a truck mounted brake assembly
Inventor: MORIARITY MICHAEL J
IPC: B61H13/38
Filed: 2002-04-19
Abstract: An overload protection device (10) for a truck-mounted railcar brake assembly comprising of: a body member having a first end (14), a second end (16), and at least one cavity (18) of a predetermined size and shape disposed within said body member (12).  A compression member of a predetermined size, shape, material, and load rating, the compression member compressed to a predetermined initial load, and disposed within the cavity of the body member. A first means (22) secured to and disposed on the first end of the body member for engagement with a portion of such brake assembly. A second means (24) disposed on said second end of the member for attaching to a force-transmitting member. A first portion (32) of said second means engageable with said compression member (20) for transmitting an excess force generated from such railcar brake assembly to the compression member, whereby said overload protection device will compensate for a potential railcar brake overload condition.
Patent NZ-524462-A (NZ)
Title: Flower-bud formation suppressor gene and early flowering plant
Inventor: KOTODA NOBUHIRO
IPC: C12N5/04
Filed: 2003-02-27
Abstract: An isolated protein comprising an amino acid sequence encoding a flower-bud formation suppressor, namely a terminal flower 1-like protein from an apple plant, transformants comprising said protein and the use of said protein to suppress early flowering in a plant, preferably a perennial.
Patent NZ-527998-A (NZ)
Title: Laminated film and method of forming film
Inventor: TANEDA TAKAHIRO
IPC: H01L39/24
Filed: 2001-12-10
Abstract: A film having a uniform thickness and having a crystal axis parallel to a main surface of a substrate is manufactured. In a deposition method, a film is formed by scattering a deposition material from a target (12) surface and growing the scattered deposition material on a main surface (100a) of a substrate (100). The method includes the steps of positioning the substrate (100) into a first state where the distance between one end (100f) and the target (12) is small and the distance between the other end (100e) and the target material (12) is relatively large, forming a first film (110) on the substrate (100) in the first state, positioning the substrate (100) into a second state where the distance between one end (100f) and the target (12) is large and the distance between the other end (100e) and the target (12) is small, and forming a second film (120) on the first film (110) in the second state.
Patent NZ-532427-A (NZ)
Title: Modification of feeding behavior using PYY (peptide YY) and its agonists such as NPY (neuropeptide Y)
Inventor: COWLEY MICHAEL
IPC: A61K38/22
Filed: 2002-09-24
Abstract: Disclosed are methods for decreasing calorie intake, food intake, and appetite in a subject. This includes peripherally administering a therapeutically effective amount of PYY or an agonist thereof to the subject, thereby decreasing the calorie intake of the subject.
Patent NZ-537922-A (NZ)
Title: Pitch based graphite fabrics and needled punched felts for fuel cell gas diffusion layer substrates and high thermal conductivity reinforced composites
Inventor: CRAWFORD JAMES
IPC: D04H1/46
Filed: 2003-07-30
Abstract: Disclosed herein is a yarn comprised of a pitch precursor material which has been stretch broken from a first filament count and drawn to a second filament count, with the second filament count being less than the first filament count. Also disclosed is a method of making a graphite fabric comprising the steps of: providing a pitch precursor yarn of a first filament count; stretch breaking and drawing said yarn into a second filament count which is less than the first filament count; forming said yarn into a fabric or felt; and heat treating said fabric or felt to convert the fibers into graphitic fibers. The disclosed pitch precursor yarn, which is stretch broken and formed into a fabric or felt which is heat treated into graphitic fiber media is suitable for fuel cell gas diffusion layer substrates and high thermal conductivity reinforced composites.
Patent NZ-543369-A (NZ)
Title: Polypeptide having a plurality of modified growth hormone receptor binding domains of growth hormone
Inventor: ROSS RICHARD
Filed: 2002-12-06
Abstract: Disclosed is a chimeric polypeptide comprising: i) a first modified growth hormone receptor binding domain of growth hormone wherein the modification is the addition, deletion or substitution of a least one amino acid residue; and ii) a second modified growth hormone receptor binding domain of growth hormone wherein the modification is the addition, deletion or substitution of at least one amino acid residue, characterized in that the binding domains are fused in tandem and the modification is to site 2 in at least one binding domain of growth hormone and wherein the polypeptide is an antagonist and the chimeric polypeptide does not include a growth hormone binding domain of growth hormone receptor.
Patent NZ-543953-A (NZ)
Title: Method and compositions for treating mammalian nerve tissue injuries
Inventor: SHI RIYI
IPC: A61K31/765
Filed: 2002-04-24
Abstract: Disclosed is the use of a biomembrane fusion agent for the preparation of a pharmaceutical composition for treatment of an injury to nerve tissue of a patient in need thereof, wherein the biomembrane fusion agent comprises an amphipathic polymer.
Patent NZ-544307-A (NZ)
Title: Compositions comprising balaglitazone and further antidiabetic compounds
Inventor: WASSERMANN KARSTEN
IPC: A61K31/216
Filed: 2004-06-24
Abstract: Disclosed is a pharmaceutical composition comprising balaglitazone and one or more dipeptidyl peptidase-IV inhibitors. Also disclosed is the use of balaglitazone in combination with one or more dipeptidyl peptidase-IV inhibitors in the production of a medicament for treating conditions benefiting from a decrease in insulin resistance, a reduction of plasma glucose levels, a reduction of plasma fatty acid levels, a reduction of plasma triglyceride levels or a reduction of VLDL levels, in a patient in need thereof.
Patent NZ-545195-A (NZ)
Title: Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
Inventor: STEEVES RITA
IPC: A61K47/54
Filed: 2004-10-12
Abstract: Disclosed is a cell-binding agent maytansinoid conjugate having at least one maytansinoid linked to a cell-binding agent via a non-cleavable linker, wherein the cell-binding agent is an antibody, a single chain antibody or an antibody fragment that specifically bind to a target cell, wherein the antibody, single chain antibody or antibody fragment comprises a human constant region.
Patent NZ-546305-A (NZ)
Title: Method and device for installation of guide rails in a lift shaft
Inventor: CRUZ PABLO
Filed: 2006-03-31
Abstract: A method for installation of elevator car guide rails 10 in a lift shaft 1 is disclosed. The method includes the steps of fastening several guide rails to a common support means 13, such as a lifting cable, and pulling the support means up the lift shaft with the guide rails hanging in a vertical position one after another. The method allows easy conveyance of multiple rails to their installation locations simultaneously.
Patent NZ-550411-A (NZ)
Title: Polyvalent viral vectors and a system for production thereof
Inventor: GAO GUANGPING
IPC: C12N15/861
Filed: 2005-04-27
Abstract: Provided is a plasmid comprising adenoviral genomic nucleotide sequences to be packaged into a polyvalent adenoviral capsids and: (a) a first movable cassette located in a first locus of an adenoviral genomic sequence, said first movable cassette comprising nucleic acid sequences comprising a first colorimetrically detectable reporter gene operably linked to sequences that will direct expression thereof, said movable cassette being flanked by a first set of rare restriction enzyme sites composed of a rare restriction enzyme site at the 5' end of the first movable cassette and a rare restriction enzyme site at the 3' end of the first movable cassette; and (b) a second movable cassette located in a second locus of the adenoviral genomic sequence which is non-contiguous with the first locus, said second movable cassette comprising nucleic acid sequences comprising a second colorimetrically detectable reporter gene operably linked to sequences that will direct expression thereof, said movable cassette being flanked by a second set of rare restriction enzyme sites composed of a rare restriction enzyme site at the 5' end of the first movable cassette and a rare restriction enzyme site at the 3' end of the second movable cassette; wherein the product of said first detectable reporter gene and the second detectable reporter gene are distinguishable from one another by colour, and wherein the first and second set of rare restriction enzyme sites differ, said rare restriction enzyme sites being such that a corresponding rare restriction enzyme cuts these sites and neither the genetic element carrying the viral genome nor other locations in the viral genome are cut by the enzyme.
Patent NZ-551439-A (NZ)
Title: Pyrrolopyridine derivatives and their use as CRTH2 antagonists
Inventor: BALA KAMLESH
IPC: A61K31/437
Filed: 2005-06-16
Abstract: Disclosed are compounds of formula (I) and processes for preparing them in free or salt form, wherein: Q is a bond; R1 and R2 are, independently, H or C1-C8alkyl; R3 is C1-C8alkyl; R4 and R5 are, independently, halogen, C1-C8alkyl, C1-C8-haloalkyl, a C3-C15- carbocyclic group, nitro, cyano, C1-C8-alkylsulfonyl, C1-C8-alkoxycarbonyl, C1-C8-alkoxy or C1-C8-haloalkoxy; R6 is H or C1-C8-alkyl; W is a mono or bicyclic ring as defined in the specification; X is -SO2-, -CH2-, -CH(C1-C8-alkyl)-, -CON(C1-C8-alkyl)- or a bond; m and n are each, independently, an integer from 0-3; and p is 1. Compounds of the invention are useful for the treatment of diseases mediated by the CRTh2 receptor, in particular inflammatory and allergic conditions.
Patent NZ-553302-A (NZ)
Title: Mask assembly with frame that can be flexed about longitudinal axis
Inventor: BERTHON-JONES MICHAEL
IPC: A61M16/06
Filed: 2003-11-06
Abstract: A mask assembly (412) adapted to be positioned on the face of a patient for non-invasive positive pressure ventilation is disclosed. The mask has a frame (436) with rigid side portions (440) connected by flexible base (438) and apex (442) portions. The frame can be resiliently flexed about a longitudinal axis defined by the apex and base portions to accommodate the shape of the patient's face. A mask body (422) and a cushion are coupled to the frame, and a headgear comprising at least one strap is also secured to the frame.
Patent NZ-553507-A (NZ)
Title: Biologically active peptides
Inventor: WONG WAI MING
IPC: A61P17/14
Filed: 2002-07-11
Abstract: A substantially pure and biologically active peptide known as SEQ ID 1 (PTTKTYFPHF). This includes a nucleic acid that has a sequence coding for this biologically active peptide and a pharmaceutical formulation produced therefrom. This peptide has the ability to modulate immune activity and growth of cancer, specifically sarcomas and melanomas. This peptide can also have a secretory signal peptide for secretion of the protein from the micro-organism in which it is expressed.
Patent NZ-555645-A (NZ)
Title: LNA oligonucleotides and the treatment of cancer
Inventor: ASKLUND MARLENE
IPC: A61K31/7088
Filed: 2005-11-09
Abstract: Disclosed are pharmaceutical compositions comprising at least one taxane compound and an LNA oligonucleotide having the sequence of SEQ ID No: 28. The LNA oligonucleotides exhibit advantageous properties over known oligonucleotides in the inhibition of Survivin expression by means of an anti-sense mechanism, and thereby lead to reduction or inhibition of tumour development in vivo.
Patent NZ-562633-A (NZ)
Title: Gauge with illuminated dial and pointer
Inventor: VERDOUW JAMES
IPC: G01D11/28
Filed: 2006-04-28
Abstract: A gauge having an illuminated dial and pointer is disclosed. The gauge comprises of: a light-transmitting dial plate; at least one light source positioned rearwardly from a rear surface of the dial plate; a light ring; and a light-transmitting pointer mounted for rotational movement about an axis normal to the dial plate. The light-transmitting dial plate has a front surface with indicia for a variable represented by the dial and the light from the light source is transmitted by the dial plate to the front surface thereof. The light ring is positioned between the at least one light source and the dial plate. The pointer has a hub concentric with the axis normal to the dial plate and extending through the dial plate, projecting both forwardly and rearwardly from the plate. The pointer also has an indicator projecting laterally from the hub across a portion of the front surface of the dial plate. The hub has a small diameter portion located behind the dial plate, a large diameter portion extending through the dial plate, and a tapered transition portion between the small-diameter and large-diameter portions. The tapered transition portion is located closer to the rear surface of the dial plate than the light source and forms a tapered outer surface configured for intercepting light from the light source. This is configured so that the light enters the hub and propagates forwardly through the hub and laterally from the hub into the indicator so the indicator is illuminated.
Patent NZ-567507-A (NZ)
Title: Food holding cabinet with removable tray covers
Inventor: JONES DOUGLAS S
IPC: A47J36/34
Filed: 2006-10-17
Abstract: A food holding cabinet having a housing defining a heating chamber for holding a covered food tray in a tray location has a pair of elongated rigid rods mounted to the housing for suspending a food tray cover thereon in a position above the tray location. A front rod extends across the opening to the heating chamber and supports the front end of the tray cover and a rear rod supports the rear of the cover. When a food tray is inserted into the tray location, it lifts and supports the cover. When the tray is removed, the front rod prevents removal of the cover along with the underlying tray. The front rod is spring-loaded to be pulled away from the housing to facilitate removal of the cover. A tray cover is also provided.
Patent NZ-570190-A (NZ)
Title: Pharmaceutical composition comprising a bi-cyclic compound and method for stabilizing the bi-cyclic compound
Inventor: HIRATA RYU
IPC: A61K9/48
Filed: 2007-01-23
Abstract: Disclosed is a composition containing a bicyclic compound of formula (I) and a polyol and/or fatty acid ester which is an ester of a fatty acid and an alcohol selected from the group consisting of propylene glycol, polyethylene glycol and a C1-6 monovalent alcohol. Also disclosed is a soft gelatine capsule formulation containing a compound of formula (I) and a soft gelatin capsule shell comprising gelatin and a polyol as a plasticizer, and a mixture comprising said bi-cyclic compound and a pharmaceutically acceptable vehicle, which is filled in the shell. Further disclosed is the method of making the composition of a compound of formula (I) and a polyol and/or a fatty acid ester; and the method of making a soft gelatine capsule containing a compound of formula (I), a pharmaceutically acceptable vehicle and a shell containing gelatine and a polyol
Patent NZ-572074-A (NZ)
Title: Method and system for monitoring the condition of livestock
Inventor: MOTTRAM TOBY
IPC: A61D17/00
Filed: 2007-04-18
Abstract: A system (115) for monitoring the condition of livestock comprises a plurality of sensors for sensing a plurality of orientation and movement parameters of a subject; a processor for deriving a plurality of different behavioural parameters of the subject from the sensed plurality of orientation and movement parameters and determining a plurality of status conditions of the subject and at least one transmitter for transmitting data, wirelessly, to a central computer. The status conditions include at least one of fertility, oestrus and prediction of onset of parturition. A method for monitoring the condition of livestock and a device for monitoring the condition of livestock are also disclosed. The device comprises attachment means for attaching the device to a subject; and the above described system (115). The attachment means can be a neck collar (101), an ear tag (103), head collar (105), leg attachment (107), transdermal patches (109, 111) or ingested bolus (15 113).
Patent NZ-572610-A (NZ)
Title: High-strength, low-temperature stable herbicidal formulations of fluroxypyr esters
Inventor: LINTON MARK R
IPC: A01N25/02
Filed: 2007-06-29
Abstract: Disclosed is a high-strength, low-temperature stable herbicidal formulation comprising a mixture of a fluroxypyr ester, a surfactant or mixture of surfactants, and an N,N-dimethyl (C6-C12) alkylamide as a solvent wherein the formulation contains from about 430 grams per litre (g/L) to about 600 g/L of the fluroxypyr ester, from about 100 g/l to about 200 g/L of surfactant and from about 300 g/L to about 560 g/L of N,N-dimethyl (C6-C12) alkylamide as a solvent. Particular embodiments of the mixture include fluoxypyr meptyl ester and a mixture of N,N-dimethyloctamide/decanamide.
Patent NZ-574860-A (NZ)
Title: Wheeled vehicle, typically mobility scooter, with central and two outer front wheels for improved steering and stability
Inventor: NICHOLLS GRAHAM REGINALD
IPC: B62K5/08
Filed: 2007-05-11
Abstract: A vehicle comprising: steering means for operation by a user,- one or more rear ground- engaging wheels; a first front ground-engaging steerable wheel (34) located substantially in the centre at substantially the front of the vehicle; second and third front ground- engaging wheels (36, 37) located either side of the first front ground-engaging wheel (34) with adjustment means for adjusting the steer angle and the height depending on the steer angle of the first front ground- engaging wheel, the adjustment means being configured such that: when the first front ground- engaging wheel (34) has a straight-ahead steer angle, the steer angles of the second and third front ground-engaging wheels (36, 37) are also straight-ahead and all three front ground- engaging wheels are in contact with the ground; and when the steer angle of the first front ground-engaging wheel (34) is turned such that motion of the vehicle would describe a curve, the steer angle of the front ground-engaging wheel on the outside of said curve is turned at least partly towards the steer angle of the first front ground-engaging wheel, the steer angle of the front ground-engaging wheel on the inside of said curve is not substantially turned towards the steer angle of the first front ground-engaging wheel, and the height of the front ground-engaging wheel on the inside of said curve is raised relative to the height of the front ground-engaging wheel on the outside of said curve, the first front ground- engaging wheel and the front ground-engaging wheel on the outside of said curve remaining in contact with the ground.