baber/WOPTO huggingface dataset:
Patent FI-105482-B (FI)
Inventor: CHAUDHURI BHABATOSH
IPC: C12R1/865
Filed: 1992-12-14
Granted: 2000-08-31
Abstract: The invention concerns novel DNA molecules encoding a modified, endoplasmic reticulum-located "dibasic processing endoprotease" and the use of said endoplasmic reticulum-located "dibasic processing endoprotease" for the correct processing of heterologous polypeptides in transformed hosts.
Patent FI-101854-B (FI)
Inventor: BEUTNER DIETER
IPC: A61P9/08
Filed: 1993-12-09
Granted: 1998-09-15
Abstract: The invention relates to a dermal plaster for the transdermal administration of nitroglycerin, consisting of, besides a support film and a removable protective film, a nitroglycerin-containing, in particular adhesive, composition based on a crosslinked acrylate/vinyl acetate copolymer whose monomer mixture employed for the polymerisation contains 21 to 40 % by weight of vinyl acetate, 55 to 70 % by weight of a C2-8-alkyl acrylate and 3 to 10 % by weight of a C2-4-hydroxyalkyl acrylate and which is crosslinked after admixture of a conventional crosslinker and the nitroglycerin additionally by heating and removing solvents which are present. The specific adhesive composition according to the invention has not only a high absorption capacity but also a high and controllable release capacity for nitroglycerin so that the release area of the plaster necessary for the amount released each day can be kept small, and thus the costs of the plaster are very low. At the same time, owing to the simple adhesive composition, the preparation process is simplified, the addition of other substances to increase the transepidermal transport of substances is unnecessary and thus the costs of the plaster are further kept low and the risk of skin irritation is avoided.
Patent FI-100557-B (FI)
Inventor: STENMAN ULF-HAAKAN
IPC: G01N33/50
Filed: 1994-08-26
Granted: 1997-12-31
Abstract: PCT No. PCT/FI95/00453 Sec. 371 Date Aug. 13, 1997 Sec. 102(e) Date Aug. 13, 1997 PCT Filed Aug. 24, 1995 PCT Pub. No. WO96/07104 PCT Pub. Date Mar. 7, 1996The invention relates to an immunoassay for trypsinogen-2 wherein an amount of analyte in a sample is measured, said analyte being either trypsin-2 complexed with alpha-1-antitrypsin (trypsin-2-AAT) in serum, or trypsinogen-2 in urine. According to a preferred embodiment, the trypsin-2-AAT complex or free trypsinogen-2 are measured by non-competitive methods employing at least two different antibodies. The methods are useful for the diagnosis of patients with pancreatic disease, especially pancreatitis.
Patent FI-105938-B (FI)
Inventor: LEFFERTS JOHANNES
IPC: D21F1/00
Filed: 1995-02-03
Granted: 2000-10-31
Abstract: A linked strip comprises many interlocking synthetic spirals (10) where each winding has a flat shank (12) and a sharp bend (11). The bends of one spiral interlock like a zip with the bends (11', 11") of neighbouring spirals to form channels for securing wires (14) so to connect the spirals. Here, flat wires (15) in the spirals for reduction of linked strip air permeability are tilted w.r.t. the strip plane. A process for strip prodn. entails inter-positioning the spiral windings (11) to overlap, insertion of the securing wires (14) in the channels so formed transverse to the strip path, and insertion of the flat wires (15) into the spirals. Here, it is just after this sequence that the linked strip is thermally locked. The flat wire (15) in the spiral (10) interior is wider than the smallest distance between the two adjacent spirals, runs above one and under the other spiral securing wire (14), is clamped between the spiral inner surface and the outer surfaces of the two adjacent spirals and tapers to a point along its lengthwise edge where the edge angle is less than the wire tilt. The spirals can be formed in the cross-sectional shape of a parallelogram with different diagonals where the securing wires (14) are laid in the angles of the longer diagonal and the flat wires (15) in those of the shorter. The flat wires shrink in their longitudinal direction and expand transversely when thermal fixing occurs and so are inserted with an extra length so that after thermal fixing their length coincides with the breadth of the spiral linked ribbon.
Patent FI-116271-B (FI)
Inventor: COLLINS DAVID
IPC: A61K47/48
Filed: 1995-06-05
Granted: 2005-10-31
Abstract: The invention relates to stable compositions of proteins and related methods wherein a protein capable of transitioning into the molten globular state is contacted with a negatively charged lipid vesicle, thereby stabilizing the protein against thermally-induced aggregation, denaturation, and loss of activity. The protein: phospholipid complex directly stabilizes the secondary and tertiary structure of the protein, and the compositions are useful in high temperature formulations and in novel delivery vehicles.
Patent HU-186700-B (HU)
Inventor: SZEKELY GEZA
IPC: C08L63/00
Filed: 1983-05-18
Abstract: A találmány tárgya eljárás olyan tartósan stabil epoxigyanta alapú, vizes diszperziós bevonóanyag előállítására, amely beton- vagy fém felületekre könnyen felhordható, ezek védelmét szolgálja, továbbá régi vagy új betonfelületek összekapcsolására, illetve ragasztására is alkalmas. Az eljárást az jellemzi, hogy az JU komponenst . — amely ismert epoxigyantát, 100 tömegrész gyantára számítva 5-40 tömegrész stabilizáló adalékot éspedig 1-4 szénatomszámú monoalkohol, előnyösen etilalkohol és glicerin elegyét, vagy poliglikoléter és szulfonált szé íhidrogén alkáli fémsójának elegyét, továbbá az ,A’ komponens teljes mennyiségére számítva 0-20 tömegrész cementet, 0-20 tömegrész hőre lágyuló polimert és egyéb ismert adalékanyagokat, így ásványi töltőanyagot, pigmentet, tartalmaz - összekevernek egy olyan ,B’ komponenssel, amely oligoaminoamid vagy maleinsavinhidriddel módosított zsírsav aminoamid térhálósitt t és adott esetben a térhálósító mennyiségére számítva 10-20 tömegrész alifás vagy aromás ketont és 60 -200 tömegrész ásványi töltőanyagot, pigmentet tartalmaz, majd a diszperziót 0—300 tömegrész csapvízzel fel! ígítják. -1-
Patent HU-189111-B (HU)
Title: Process for producing thiazol derivatives
Inventor: MARZONI GIFFORD PURNELL
IPC: C07D277/14
Filed: 1984-05-11
Abstract: Certain 4-halomethylthiazoles having a 2-substituted-aminomethyl group are pepared by reacting an amino- thioamide with a dihalopropanone in the presence of a haloalkane and a bicarbonate, and dehydrating the resulting intermediate.
Patent HU-193168-B (HU)
Inventor: KELEMEN ANDRAS
IPC: G01N21/17
Filed: 1983-06-14
Abstract: A találmány tárgya eljárás és berendezés, valamint mintakamra kondenzált halmazállapotú kis és közepes abszorpciójú átlátszó vagy nem átlátszó minták fotoakusztikus vizsgálatára. Az eljárás szerint egy modulált fénynyalábot két részre osztunk, majd az átmenő nyalábot mintakamrába, az eltérített nyalábot pedig referenciakamrába vezetjük. Ezután a mintakamrában a minta segítségével, a referenciakamrában pedig referenciamintával hanghullámokat keltünk, melyeket erősítés után érzékelünk. Érzékelés után mindkét jelet külön-külön tovább erősítjük, majd fázisérzékenyen egyenirányítjuk és képezzük a két jel hányadosát. Ezután a hányadost a monokromatikus fényforrás hullámhosszának függvényében előnyösen egy X-Y íróval megjelenítjük. r A találmány szerinti berendezés lényege, hogy nyalábosztója (16) és az átmenő nyaláb irányában nyitott Helmholtz-rezonátoros mintakamrája (21), az eltérített fénynyaláb irányában pedig referenciakamrája (22) van. A két kamra kimenetére egy-egy lánckapcsolású erősítő (23,24) és fázisérzékeny egyenirányító (25, 26) csatlakozik. A két kimenetre hányadosképző (27), a hányadosképző és monokromátor (14) kimenetére megjelenítő (28a), pl. X-Y író csatlakozik. A nyitott mintakamra fénybevezető nyílással ellátott első és mintatartóval ellátott hátsó zárószervből áll, melyek között mikrofonnal ellátott záróköpeny van. A mintakamra belső tere Helmholtz-rezonátornak van kialakítva. (1 ábra).  Lobra -1-
Patent HU-191467-B (HU)
Inventor: NITTA ISSEI
IPC: C07J7/00
Filed: 1982-07-19
Abstract: A találmány tárgya eljárás új, (I) általános képletű 21-ha1ogén-17a-alkanoiloxi-szteroidszármazékok előállítására, amelyek kedvező feltételek között alkalmazhatók köztitermékként kortikoszteroid hormonok, pl. hidrokortizon vagy prednizolon előállításánál. A képletben a szaggatott vonal adott esetben jelenlevő kettős kötést jelent, A jelentése 1-4 szénatomos alkanoil-oxicsoport és Y jelentése jód-metilcsoport vagy bróm-metilcsoport. A monojód-alkanoil-szteroidszármazékot egyébként egyező szerkezetű, de a 21-helyzetben dijód-szubsztituált kiindulási anyagból állítjuk elő, azt hidrogéntartalmú szerves oldószerrel kontaktálva vagy egy ditionitvegyület alkalmazásával redukálva. A monobróm-alkanoil-szteroidszármazékot egyébként egyező szerkezetű, de a 21-helyzetben dibróm-szübsztituált kiindulási anyagból állítjuk elő, azt egy foszfit-vegyülettel reagáltatva.  (l) -1-
Patent HU-195872-B (HU)
Title: Adjusting device particularly forlimiting and/or damping the joint moving of articulated vehicles by hydraulic or pneumatic adjusting element removable in axial direction
Inventor: STAISCH DIETHER
IPC: B62D53/08
Filed: 1984-08-31
Abstract: A fluid flow control apparatus having an adjustable throttling arrangement for controlling the flow of fluid between working cylinders associated with sections of an articulated vehicle, has a housing which is essentially symmetric in shape. Two working connections are formed at symmetrically opposite ends of the housing and connect to the working cylinders. Two passageways, formed in the housing to connect the two working connections, are also symmetrically formed and are approximately equivalent in length. The first passageway uses a check valve arrangement to restrict fluid flow from the first working connection to the second working connection while the second passageway uses a similar check valve arrangement to restrict fluid flow in the opposite direction. The two passageways interconnect at a crossover duct which acts as a guide for the throttling arrangement. A slide member, having a throttle face formed on a circumferential surface, is movable in relation to a throttle surface formed on the housing such that, a restriction is introduced to the fluid flow in both the first and second passageways. A motor drive/transmission arrangement controls movement of the slide in response to bending parameters established for the articulated vehicle. A relief valve provided in the first passageway, bypasses the throttling arrangement should an excessive fluid pressure occur.
Patent HU-188708-B (HU)
Title: Process for the production of infusion of mixed herbs suitable for the regeneration of hepatic and bilious function
Inventor: FORST KAROLY F
Filed: 1981-11-06
Abstract: A tea mixt. suitable for restoring liver and gall functions consists of fifteen components, among the more important of which are nettle leaves and beetroot. The tea is prepd. from the components by soaking and subsequent boiling.
Patent HU-186990-B (HU)
Inventor: SCHUBAUER KALMAN
IPC: E04H5/08
Filed: 1982-11-12
Abstract: A találmány szerinti kettős fóliafalú sátorszerkezet lényege, hogy külső fóliaborítása és sátorvázra helyezett belső fóliaborításra fektetett, egy középsíkból felfelé és lefelé ismétlődően váltakozva kiálló — célszerűen kisebbedő kerületű — egyenes vagy görbe alkotójú, esetleg torzfelületű palástból és a középsíkkal párhuzamos fedőlapból álló, a középsíkra merőleges állótengelyű, belül üres téridomokkal kiképzett, átlátszó vagy áttetsző pl. PVC anyagú térköztartó elemre van ráhelyezve.  -1-
Patent HU-191021-B (HU)
Title: Process for preparing trimethyl-silyl-esters of n-substituted carbamidic acid
Inventor: KNAUSZ DEZSEO
IPC: C07F7/18
Filed: 1985-11-01
Abstract: The invention relates to new compounds of the general formulae (I) and/or (II),    <IMAGE>  (I)   <IMAGE> (II)  wherein R1 is a C1-6 alkyl or an aralkyl group, and R2 is hydrogen or a C1-6 alkyl group. According to another aspect of the invention there are provided processes for the preparation of these compounds. The compounds of the general formulae (I) and/or (II) are utilizable for the oxymation and/or trimethylsilylation of any substrate bearing an oxo group and/or a silylable polar hydrogen. The compounds of the general formula (VI): (CH3)3Si-Y-Z=N-OR1 (VI) wherein R1 is as defined above Y is oxygen, nitrogen or sulphur atom or a carboxylate anion, and Z is the skeleton of the substrate, said compounds being formed in the oxymation and/or trimethylsilylation reaction, are also within the scope of the invention.
Patent HU-204897-B (HU)
Title: Process for producing monoclonal antibodies capable of recognizing n-acetylneuraminic acid of beta-configuration, as well as hybridomas producing same
Inventor: KAWAMURA ATSUSHI
IPC: C07K16/30
Filed: 1988-11-11
Abstract: A hybridoma producing a monoclonal antibody specific to N-acetylneuraminic acid or a derivative thereof in the beta-arrangement as an epitope or antigenic determinant is herein disclosed. The monoclonal antibody produced by the hybridoma can be used in clinical purposes such as diagnosis and/or prognosis of a certain kinds of cancers and acute inflammatory diseases. The hybridoma can be generated by fusing (i) B cells or lymphocytes obtained by immunizing an animal with an N-acetylneuraminic acid or a derivative thereof in beta-arrangement as an antigen and (ii) myeloma cells.
Patent IT-1242299-B (IT)
Title: Equipment for simulating ski-training
Inventor: ACCIACCAFERRI LUCIO
IPC: A63B/
Filed: 1990-11-02
Granted: 1994-03-04
Abstract: The equipment for simulating ski-training consists: - of a supporting structure whose shape is designed to withstand the stresses generated during its use, and which is capable of offering solid anchorage points for the components which make up the mechanisms of the said simulator; - of 2 front pendulums and 2 rear pendulums which are able to swing freely and are fitted with elastic elements which provide suspension in the direction of their principal axis; - of 4 stop bars which are also able to swing freely and follow the movement of the pendulums and which, via suitable jaws integral with the footboards, can "lock" the latter on the said bar; - of 4 locking jaws which are located on the footboards in the region of the pendulums and which are capable of halting the suspension as a result of the inclination of the said footboard, brought about by the user with a movement identical to that performed by a skier when assuming the "snowplough" position with his skis; - of a system of supports consisting of ordinary ski poles resting on special surfaces or of suitable adjustable handlebars having fixed or jointed handgrips; - of two footboards, each of which is connected to a front pendulum and to a rear pendulum in order to allow the transverse swing of the footboards independently of each other. As an alternative to the two footboards, in order to simulate the use of a monoski or of a snowboard, it is possible to use a single footboard connected to two front pendulums and to two rear pendulums. <IMAGE>
Patent IT-1233662-B (IT)
Title: Device for the punching of metal sheets
Inventor: PERAZZOLO EUGENIO
IPC: B21J/
Filed: 1989-02-21
Granted: 1992-04-13
Abstract: This is a description of a device for the punching of metal sheets including:several initial punch units (3, 217);several initial die units (4, 221)a work station (12) with a hammer (13), initial mechanisms (16) designed to cause a pre-determined rotation to a punch tool (28) and secondary mechanisms (118) designed to cause a pre-determined rotation to a die tool (126); and a second punch unit (201) with its own tool (33) designed, when this is situated at the work station (12), to tighten, by action of the hammer (13), with its own plate, (203) the sheet towards a die tool (205) of the second die unit (202).The abovementioned primary (16) and secondary (118) mechanisms are designed, after the tightening of the sheet, to cause a predetermined rotation of the tools (32 and 205) of the second units (201 and 202) so as to impress the same rotation on the sheet (figures 5 and 6).
Patent IT-1243214-B (IT)
Title: Device which can be opened and hermetically resealed and which simultaneously cuts through the wall of the sealed containers to which it is applied, to allow controlled dispensing
Inventor: MARCHI ROMOLO
Filed: 1990-10-25
Granted: 1994-05-24
Abstract: The device essentially consists of a shell 1 applied to the top of the container 15; the said shell 1 contains a rotary diaphragm 2, equipped with at least one cutting tooth 6 and with a mouth 12 which corresponds to a dispensing aperture 4 formed in the shell 1; the diaphragm 2 is rotated by means of the external lever 3. <IMAGE>
Patent LT-3288-B (LT)
Title: Substituted pyrroles with terapic activity
Inventor: HARRIS WILLIAM
IPC: C07D471/04
Filed: 1994-05-09
Abstract: The invention provides compounds of the formula <CHEM> wherein R<1> represents lower alkyl, lower cycloalkyl, aryl or lower aralkyl, R<2> represents hydrogen, aryl or lower alkyl optionally substituted by hydroxy, acyloxy, amino, mono(lower alkyl)amino, di(lower alkyl)amino, carboxy, lower alkoxycarbonyl or aminocarbonyl and m and n stand for 1 or 2, as well as pharmaceutically acceptable salts of acidic compounds of formula I with bases and of basic compounds of formula I with acids, which are useful in the control or prevention of illnesses, especially in the control or prevention of inflammatory, immunological, oncological, bronchopulmonary, dermatological and cardiovascular disorders, in the treatment of asthma, AIDS or diabetic complications or for the stimulation of hair growth.
Patent LT-3688-B (LT)
Title: Composition for bitter alcoholic beverage
Inventor: SARGUNAS GEDIMINAS
IPC: C12G3/06
Filed: 1994-08-09
Abstract: Invention applies to the vodka-liqueur industry. This invention creates a new bitter kind of brandy composition that consists of colour, citric acid, juniper berries, alcohol-water mix and additionally introduced sweet-flag root-stock, over ground part of citric balm maintaining the following ingredient ratio of the produced bitter kind of brandy, kg/1,000 decalitres: citric acid 0.25-0.35, sweet-flag root-stock 0.035-0.065, juniper berries 7.5-10.5, over ground part of citric balm 9.66-11.34, colour 55.0-65.0, alcohol-water mix - the remaining amount up to 1,000 decalitres. The newly created bitter kind of brandy composition has the following indicator: 38 % strength.
Patent LV-14925-B (LV)
Title: The method and the device for water enrichment with oxygen in fish breeding systems with closed water supply
Inventor: TRAČUKS Sergejs
IPC: C02F3/04
Filed: 2013-05-07
Abstract: Invention is related to fish breeding, in particular to methods and devices for oxygenation of water in a fish-breeding pool with a closed water loop. Invention comprises a method and a device, where the water flow from a clearing block flows over a partition wall (1), then over a Zshaped gutter (4), comes into an oxygenating camera (3), limited by the Z-shaped  gutter (4) and a partition wall (5), where to the Zshaped  gutter (4) a netted basket (6) with filler (7), covered by a perforated plate (8) is attached. A hermetic shell (9) with a nozzle (10) for supply of oxygen covers the camera (3) over the top. Oxygen directly interacts with the water flow coming into the camera (3), then the water falls down through the filler (7) and splashes in droplets throughout the oxygen-filled free space, limited by the walls of the filler basket (6), the hermetic shell (9) and the surface of the water in the fish-breeding pool (2), creating an effect of raining. An intensive and natural oxygenation of water happens.  The device can be modified and equipped by an UV-lamp, enabling simultaneous oxygenation and disinfection by the UV-radiation.
Patent LV-10725-B (LV)
Title: Brain derived neurotrophic factor
Inventor: CAROLYN HYMAN
IPC: C07K16/22
Filed: 1993-10-06
Abstract: The present invention relates to nucleic acid sequences encoding brain derived neurotrophic factor (BDNF), as well as BDNF protein produced in quantity using these nucleic acid sequences, as well as fragments and derivatives thereof. In addition, the invention relates to pharmacologic compositions and therapeutic uses of BDNF, having provided, for the first time, the means to generate sufficient quantities of substantially pure BDNF for clinical use. In a specific embodiment, BDNF may be used to promote the survival of substantia nigra dopaminergic neurons and basal forebrain cholinergic neurons, thereby providing a method for treating, respectively, Parkinson's disease and Alzheimer's disease. The invention also relates to antibodies directed toward BDNF or fragments thereof, having provided a method for generating sufficient immunogen. Further, by permitting a comparison of the nucleic acid sequences of BDNF and NGF, the present invention provides for the identification of homologous regions of nucleic acid sequence between BDNF and NGF, thereby defining a BDNF/NGF gene family; the invention provides a method for identifying and isolating additional members of this gene family.
Patent ME-01146-B (ME)
Inventor: CANGIANO STEFANO
IPC: E04C2/54
Filed: 2009-12-10
Abstract: Predmetni pronalazak odnosi se na kompozitni panel izveden od cementnog maltera kroz koji prolazi veliki broj otvora ispunjenih materijalom svetlosno propusnih tj. transparentnih svojstava. Predmetni pronalazak odnosi se takođe i na postupak izrade pomenutog kompozitnog panela
Patent MX-168553-B (MX)
Inventor: SKLAVOUNOS CONSTANTINE
IPC: C07C/
Filed: 1987-12-17
Abstract: Improved process for preparing bis(ethoxythiocarbonyl)sulfide by reacting sodium ethyl xanthate with ethyl chloroformate under pH controlled conditions.
Patent NO-142063-B (NO)
Title: Hoerselvernholder.
Inventor: PALMAER TORE GEORG
IPC: A42B3/00
Filed: 1978-06-30
Abstract: Hørselvernholder.
Patent NO-152322-B (NO)
Inventor: GOTTAUF GEORG
IPC: B02C17/22
Filed: 1980-08-21
Abstract: 1. A clamping assembly for securing protective linings to wall parts, consisting of resiliently deformable material with an U-shaped attachment means (5) open only towards the wall to be protected, consisting of metal, with inwardly directed flanges (13), engaged by railpieces (11) receiving retaining bolts (9), characterized, by the combination a) every retaining bolt (9) is attached to a railpiece (11) of a length about three to four times the bolthead diameter, b) the flanges (13) of an attachment means (5) are bent upwardly towards the bolthead (10) at an angle to the horizontal level, c) the sides (14) of the railpieces (11) are bent downwardly corresponding with the flanges (13).
Patent NO-154089-B (NO)
Inventor: KARJALAINEN ARTO
IPC: C07D233/58
Filed: 1981-02-12
Abstract: The invention provides compounds of the formula:wherein each of R<sub>1</sub>, R<sub>2</sub> and R<sub>3</sub>, which can be the same or different is hydrogen, chloro, bromo, fluoro, methyl, ethyl, methoxv, amino, hydroxy or nitro; R<sub>4</sub> is hydrogen or alkyl of 1 to 7 carbon atoms; X is(R<sub>5</sub> is hydrogen or hydroxy) and n is 1-4; and their non-toxic pharmaceutically acceptable acid addition salts. These compounds exhibitvaluable pharmacological activity and are useful in the treatment of mammals, especially as anti- hypertensive agents. Furthermore, some of the compounds have proved to possess diuretic, ß-blocking activity and/or antithrombotic activity. The compounds may be made by a variety of methods and may be incorporated in pharmaceutical compositions also comprising a compatible pharmaceutically acceptable carrier.
Patent NO-156009-B (NO)
Title: Fremgangsmaate ved fremstilling av 4-amino-1,2-hydrocarbylpyrazolidiner.
Inventor: LO YOUNG SEK
IPC: C07D231/04
Filed: 1981-08-06
Abstract: 4-nitro-l,2-hydrocarbyl-pyrazolidin fremstilles ved en ny fremgangsmåte fra 1,2-disubstituerte hydraziner og 1,3-di-(sekundær amino)-2-nitro-nitropropaner og reduseres til de tilsvarende 4-amino-l,2-hydrocarbyl-pyrazolidiner, hvilke sist-nevnte forbindelser er mellomprodukter ved fremstilling av visse farmasøytisk aktive benzamider.De nye 4-nitro-l,2-hydrocarbyl-pyrazolidiner har formelen. hvori Rog Rer valgt fra lavere alkyl, lavere-cycloalkyl eller fenyl-lavere-alkyl og kan være like eller forskjellige.