baber/WOPTO huggingface dataset:
Patent IL-65222-A0 (IL)
Title: Dihydropyridine derivatives,their production and pharmaceutical compositions containing them
IPC: A61P9/06
Filed: 1982-03-11
Abstract: Dihydropyridine anti-ischaemic and antihypertensive agents of the formula:   <IMAGE> (I)  where Y is -(CH2)2- or -(CH2)3-; R is aryl or heteroaryl; R1 and R2 are each independently C1-C4 alkyl or 2-methoxyethyl; and R3 and R4 are each independently C1-C4 alkyl or aryl-(C1-C4 alkyl); or R3 and R4 taken together with the nitrogen atom to which they are attached represent a group of the formula: <IMAGE>  where R5 is C1-C4 alkyl, aryl, aryl-(C1-C4 alkyl), benzhydryl; 2-methoxyethyl, 2-(N,N-di[C1-C4 alkyl]amino) ethyl, or cyclopropylmethyl; their pharmaceutically acceptable acid addition salts, processes for the preparation of the compounds, and pharmaceutical compositions containing them.
Patent IL-66243-A0 (IL)
Title: 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazinoquinoline-3-carboxylic acids,their preparation and antibacterial agents containing them
IPC: A61K31/495
Filed: 1982-07-06
Abstract: 1. Claims (for the Contracting States : AT, BE, CH, DE, FR, GB, IT, LI, NL, SE) Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino- quinoline-3-carboxylic acids of the formula I  see diagramm : EP0078362,P10,F3  in which R denotes hydrogen, methyl, ethyl or beta-hydroxyethyl, and their pharmaceutically usable acid addition salts, alkali metal salts and hydrates, except 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino- quinoline-3-carboxylic acid and its hydrochloride, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7- (4-methylpiperazino)-quinoline-3-carboxylic acid and 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7- (4-ethylpiperazino)-quinoline-3-carboxylic acid hydroiodide. 1. Claims (for the Contracting State LU) 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino- quinoline-3-carboxylic acids of the formula I  see diagramm : EP0078362,P11,F3  in which R denotes hydrogen, methyl, ethyl or beta-hydroxyethyl, and their pharmaceutically usable acid addition salts and hydrates.
Patent IL-95619-A0 (IL)
Title: N-azabicyclo(3.3.0)octane amides of aromatic acids and pharmaceutical compositions containing them
IPC: A61P1/08
Filed: 1990-09-10
Abstract: A compound of the formula <CHEM>  or a pharmaceutically acceptable salt thereof wherein  n is 0 or 1; and Ar is an aromatic amide moiety, which compound exhibits prokinetic activity and is a 5-HT3 antagonist.
Patent IL-96083-A0 (IL)
Title: Method for using(2-imidazolin-2-ylaminoquinoxalines to reduce or maintain intraocular pressure
IPC: A61P27/02
Filed: 1990-10-22
Abstract: The invention provides the use of a compound of the formula (I) <CHEM> and pharmaceutically acceptable acid addition salts thereof and mixtures thereof, wherein R1 is hydrogen, R2 is C1-4 alkyl or C1-4 alkoxy, the 2-imidazolin-2-ylamino group is in any of the 5-, 6-, 7- or 8-positions of the quinoxaline nucleus, and R3, R4 and R5 are each located in one of the remaining 5-, 6-, 7- or 8- positions of the quinoxaline nucleus and are independently selected from Cl, Br, hydrogen and C1-3 alkyl, for the manufacture of a medicament for reducing or maintaining intraocular pressure in a mammalian eye, for example an eye affected by glaucoma.  Also provided is the use of a compound of the formula (II) <CHEM> and pharmaceutically acceptable acid addition salts thereof and mixtures thereof, wherein R1 and R2 are independently selected from hydrogen, C1-4 alkyl and C1-4 alkoxy; the 2-imidazolin-2-ylamino group is in any of the 6-, 7- or 8- positions of the quinoxaline nucleus, R3 is hydrogen or C1-3 alkyl, and R4 and R5 each are located in one of the remaining 6-, 7- or 8-positions of the quinoxaline nucleus and are selected from Cl, Br, H and C1-3 alkyl radicals, for the manufacture of a medicament for reducing or maintaining the intraocular pressure in a mammalian eye, for example an eye affected by glaucoma. The invention also provides topical ophthalmic compositions comprising a compound of the formula (I) or (II) and an ophthalmically acceptable carrier.
Patent AU-PM756094-A0 (AU)
Title: A graphical user interface for computing devices
IPC: G06F15/02
Filed: 1994-08-19
Abstract: <P>PROBLEM TO BE SOLVED: To provide a computing device having a human/machine interface.  <P>SOLUTION: An input device 10 has a plurality of keys T, 1, 2, 3, 4 each corresponding to a separate digit of the human hand. The keys T, 1, 2, 3, 4 are arranged to match the relative sequential relation of the digits. The input device 10 is coupled to a processor device 30 in turn coupled to a visual display device 50. The processor device 30 receives instructions or data from the input device 10 and outputs information to be displayed to the display device 50. The processor device 30 is programmed to cause the visual display of indicia 60-70 wherein each indicium represents a user initiated instruction or data input and is displayed in one-to-one correspondence with the sequential relation of one or more of the keys T, 1, 2, 3, 4.  <P>COPYRIGHT: (C)2007,JPO&INPIT
Patent FI-20000136-A0 (FI)
Inventor: FILS HENRY
IPC: H04Q3/00
Filed: 2000-01-24
Abstract: The invention relates to a method for processing intelligent-network traffic provided with terminating traffic conditions. According to the method, some terminating traffic condition is set for the destination connection (10), in which case when a call comes to the connection (10) in question, the switching centre (SSP) makes an intelligent-network query of the intelligent-network control (11) and, as a result of the intelligent-network query, routes the call to at least one connection (4, 7) differing from the destination connection. According to the invention, after the connection (4) differing from the destination connection (10), the call is routed back to the destination connection (10), with at least one parameter setting to be transmitted in signalling being altered in this routing, due to an intelligent-network query by the destination connection (10) made as a consequence of the control that carried out the alteration to the parameter setting, in response to the said parameter setting alteration, to direct the switching centre (SSP) using the intelligent-network (11) to connect the call to the destination connection.
Patent FI-20001957-A0 (FI)
Inventor: MAETTOE MIKKO
IPC: H04L29/06
Filed: 2000-09-05
Abstract: The invention is concerned with a method for the secure mediation and storage of secrets, for instance the passwords of datasystems, in a telecommunications network, which comprises a sender of the message, a recipient of the message and a database attached to the recipient, in which database received messages are stored and which sender and recipient comprise the necessary attributes for the signing, encrypting, checking of signatures and decryption of messages and a telecommunications connection has been set up between the sender and the recipient. The idea of the invention is that two separate messages are sent, of which the first one consists of the actual signed and encrypted secrecy data and the second one consists of individualizing data indicating the secrecy data. The encrypted first message and the individualizing data of the second message are stored in the recipient's database. The actual signed and encrypted secrecy data can later be extracted from the database on the basis of the individualizing data.
Patent IL-104117-A0 (IL)
Title: Soluble fusion molecules with binding specificity for cell adhesion molecules
IPC: C07K14/52
Filed: 1992-12-17
Abstract: Soluble fusion molecules were prepared which contained a CD11a/CD18 specific binding region operatively linked to an immunoglobulin constant region. These molecules particularly include extracellular portions of adhesion molecules such as ICAM-1 and ICAM-2 attached to IgG constant regions. The fusion molecules described are utilized as costimulatory agents for the activation of T cells and in methods for increasing CD4+ T cell proliferative response and IL-2 induction.
Patent IL-107873-A0 (IL)
Title: Electronic surveillance
IPC: G01S7/02
Filed: 1993-12-03
Abstract: The invention relates to an electronic monitoring system, in particular for monitoring buildings, for determining the presence of unauthorised persons by means of a microwave transmitting/receiving device (9) for generating a microwave field and for irradiating therewith the area to be monitored. The microwave device (9) also serves to register the microwave signal which is reflected from the monitored region and modulated, when living beings are present in the region, with frequencies which correspond to the life functions of said living beings, and has a first signal processing device (903 to 919). The electronic monitoring system further has a signal processing device (10) for providing an actual signal amount (10.1), a first storage device (2) for storing and emitting at least one specimen signal amount (2.1, 2.3) which describes a normal state of the area to be monitored, that is to say the absence of unauthorised persons, and a comparator unit (11) for comparing with each other the actual signal amount (10.1) provided by the microwave transmitter (9.2) and the at least one specimen signal amount (2.1, 2.3) emitted by the storage device (2), which comparator unit (11) emits an output value amount (11.1) characterising the result of the comparison, the comparator unit (11) being connected to the display device (7). <IMAGE>
Patent IL-108141-A0 (IL)
Title: Polyurethane mixture and its use
IPC: C08G18/08
Filed: 1993-12-22
Abstract: A mixt. of polyurethanes comprises a first polyurethane with at least two end gps., each comprising a terminal isocyanate and a polyether; a second polyurethane with at least two end gps., each comprising a terminal isocyanate and a non-function gp.; and a third polyurethane with at least two end gps., one comprising a terminal isocyanate and a polyether and the other a terminal isocyanate and a non-fuctional gp. An aq. compsn. pref. comprises 0.005-20 wt.% of the polyurethane mixture. Also claimed is a mixt. of polyurethanes comprises a polyurethane contg. two end gps., one of which comprises a terminal isocyanate and a polyether and the other of which comprises a terminal isocyanate and a non-functional gp. Pref., the polyether is an alkyl or aryl polyether alcohol, esp. polyethylene glycol methyl ether or polypropylene glycol methyl ether. The non-functional gp. is derived from 1-octa-decanol. The three polyurethanes are present in amts. of 8.3-25, 25-75 and 16.7-50 mole %, esp. 12.5-25, 25-62.5 and 25-90 mole %.
Patent IL-117916-A0 (IL)
Title: Semi-automatic pistol having easy action cocking action
IPC: F41A3/82
Filed: 1996-04-15
Abstract: This invention discloses a semi-automatic pistol including a frame having a chamber for loading a cartridge, a barrel through which cartridges are fired, a slide normally in a forward position on the frame but movable rearwardly of the frame by the recoil produced by a fired cartridge, and a recoil spring normally coupled to the slide so as to be stressed by the rearward movement of the slide, and thereafter to relax to return the slide to its normal forward position and to load another cartridge into the chamber; characterized in that the pistol further includes a manually movable decoupling assembly which is manually movable from a coupling position, coupling the recoil spring to the slide, to a decoupling position decoupling the recoil spring from the slide and permitting the slide to be manually moved rearwardly of the frame and then to be returned to its normal forward position for loading a cartridge into the chamber. <IMAGE>
Patent IL-124806-A0 (IL)
Title: Flameless combustor
IPC: E21B43/243
Filed: 1996-12-17
Abstract: A combustor method and apparatus is provided. The method utilizes flameless combustion with one or more of three improvements to enhance ignition of the flameless combustor. A catalytic surface can be provided within a combustion chamber to provide flameless combustion at least in the vicinity of the catalytic surface at a temperature that is much lower than the autoignition temperature of fuel in air without the presence of the catalytic surface. Nitrous oxide or supplemental oxygen may also be used as an oxidant either instead of air or with air to reduce ignition temperatures. Further, electrical energy can be passed through the fuel conduit, raising the temperature of the conduit to a temperature above which the fuel will ignite when combined with the oxidant.
Patent IL-129371-A0 (IL)
Title: Screw closure with security and guarantee strip
IPC: B65D41/34
Filed: 1997-10-07
Abstract: A safety band (3) of a sealing unit (1) has two retaining noses (12a, 12b; 13a, 13b) arranged in diagonally facing pairs. The retaining  noses (12a, 12b; 13a, 13b) standing out on the clear opening of the safety band (3) are axially displaced. When the bottle (17) is closed, the pair of retaining noses (12a, 12b) is first split and then glides on the retaining rib (15). After that the retaining noses (13a, 13b) that are displaced 90 DEG  are split and also glide beneath the retaining rib (15). When the bottle is opened the retaining noses (13a, 13b) are first retained on the retaining rib (15) and the connecting webs (9) to the screw-type cap (2) are broken. Afterwards, the remaining webs (9) are also broken once the axially offset retaining noses (12a, 12b) are obstructed by the retaining rib (15).
Patent IL-131736-A0 (IL)
Title: Pair of interacting gear teeth in a rotary motor
IPC: F01C1/04
Filed: 1999-09-05
Abstract: A pair of interacting gear rims of rotary machine has been invented as a basic structural element for engines, motors and compressors. This is the most simple and most effective design to predetermine the optimal ratio of volumes of expansion and compression processes only at the expense of the form of profile of contact surface of pair gear rims of the rotary machine. This is the ideal basic element for engines, working according to an extended indicator diagram, and for single stage compressor, working with multistage effect.Applications: light and heavy vehicle engines; space power systems; heat pump systems; solar, thermal, nuclear energy systems.
Patent IL-135625-A0 (IL)
Title: Methods and devices for performing analysis of nucleic acid sample
IPC: C12N15/09
Filed: 2000-04-12
Abstract: An automated instrument and method for nucleic acid analysis is provided. The automated instrument is an integrated system including a sample processing station, a first reaction module, a second reaction module, a detection module and a control module for performing homogenous screening of broad specificity and multi-detection reactions on a nucleic acid test sample. The nucleic acid analysis performed in the instrument includes the steps of conducting a first test reaction using a low detection format, and if necessary, a selected second test reaction using a high detection format, detecting signals generated from the test reactions and processing signal data in a control module.
Patent IL-135887-A0 (IL)
Title: Unducible phosphofructokinase and the warburg effect
IPC: G01N33/50
Filed: 1998-10-30
Abstract: There is disclosed a cancer malignancy diagnostic assay comprising obtaining a sample of a body fluid or tissue, performing a sequence identity assay to look for the presence of iPFK-2 specific sequences; an anticancer pharmaceutical composition comprising a specific antisense oligonucleotide to the inventive isolated iPFK-2 sequence and a pharmaceutically acceptable oligonucleotide carrier; and a method for finding therapeutically active anti-cancer compounds comprising screening compounds for activity to inhibit iPFK-2, preferably kinase activity.
Patent IL-138522-A0 (IL)
Title: Use of cabergoline in the treatment of restless legs syndrome
IPC: A61K31/198
Filed: 1999-03-24
Abstract: The present invention provides for the use of cabergoline and other agents for the treatment of restless legs syndrome (RLS).
Patent IL-139996-A0 (IL)
Title: Use of compounds for the elevation of pyruvate dehydrogenase activity
IPC: C07C317/44
Filed: 1999-05-26
Abstract: The use of compounds of formula (I), and salts thereof; and pharmaceutically acceptable in vivo cleavable prodrugs of said compound of formula (I); and pharmaceutically acceptable salts of said compound or said prodrugs; in formula (I), Ring C is phenyl or a carbon linked heteroaryl ring substituted as defined within; R<SUP>1 </SUP>is an ortho substituent as defined within; n is 1 or 2; A-B is a linking group as defined within; R<SUP>2 </SUP>and R<SUP>3 </SUP>are as defined within; R<SUP>4 </SUP>is hydroxy, hydrogen, halo, amino or methyl; in the manufacture of a medicament for use in the elevation of PDH activity in warm-blooded animals such as humans is described. Pharmaceutical compositions, methods and processes for preparation of compounds of formula (I) are also described
Patent IL-141203-A0 (IL)
Title: Radiotherapy verification system
IPC: A61B6/03
Filed: 1999-08-06
Abstract: In radiotherapy, a high quality imaging array may be placed after the patient and opposite the radiation source to be used during radiation treatment to verify operation of a shutter system or similar device and/or to compute dose delivered to the patient. A model of the patient may be used and inverted in order to estimate values of energy fluence prior to absorption by the patient and overlapping of the various radiation beams passing through the patient. A test pattern of shutter excitation to illuminate a single ray at a time provides a simple method of obtaining the necessary model. The dose from this test pattern may be subtracted from the subsequent radiation treatment so as to provide limited or no increase in total dose to the patient.
Patent IL-142830-A0 (IL)
Title: Ammunition with a shell whose wall consists of combustible or consumable wound body
IPC: F42B5/18
Filed: 1999-10-16
Abstract: The invention aims at improving the quality of ammunition having a shell whose wall consists of a combustible or consumable wound body with at least one double layer of crossed threads. The wound body (1) forms a single piece. The winding density of the wound body (1) varies along the length of the wound body (1) so that distribution of the threads (3) optimally matches the charge of the shell (12).
Patent IL-142866-A0 (IL)
Title: Heparanase activity neutralizing anti-heparanase monoclonal antibody
IPC: A61K39/395
Filed: 1999-10-28
Abstract: A method of treating a condition associated with heparanase expression by administering a heparanase activity neutralizing monoclonal anti-heparanase antibody, the monoclonal anti-heparanase antibody being for neutralizing heparanase catalytic activity.
Patent IL-144379-A0 (IL)
Title: Particle delivery device
IPC: A61M5/315
Filed: 2000-01-27
Abstract: Replaceable components for use with a needleless syringe delivery device are provided. One replaceable component is a cartridge having a source of particles and a source of compressed gas. Another replaceable component is a nozzle assembly having a particle acceleration nozzle and a coaxial filter element. Reusable needleless syringe devices which include these replaceable components are also provided.
Patent IL-146163-A0 (IL)
Title: Toothbrush having controlled head movement
IPC: A46B5/00
Filed: 2000-04-27
Abstract: The present invention relates to a toothbrush (12) having a handle (18) formed of interlocking opposed S-curved sections, the first (26) being relatively rigid and the second (28) relatively resiliently flexible, the opposed S-curved sections forming a generally elongated figure 8, having a transverse aperture (30, 32) within each segment of the figure 8, such that during brushing the user can manipulate the relatively rigid and resiliently flexible section to position the bristle bearing face (13) of the toothbrush to conform to the arcuate configuration of the dentiture.
Patent IL-150168-A0 (IL)
Title: Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods bsed thereon
IPC: A61K38/48
Filed: 2001-02-02
Abstract: Provided herein are polypeptides that include the protease domain of a type II transmembrane serine protease (MTSP) as a single chain. Methods using the polypeptides to identify compounds that modulate the protease activity of an MTSP are provided. Also provided are MTSPs designated MTSP3 and MTSP4 and a form of an MTSP designated MTSP6.
Patent IL-178952-A0 (IL)
Title: Use of ether compounds and pharmaceutically acceptable salts thereof for the preparation of a medicament for treating or preventing a cardiovascular disease
IPC: C07C31/20
Filed: 2006-10-31
Abstract: The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising an ether compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing Alzheimer's Disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.
Patent RO-128884-A0 (RO)
Title: Agricultural additive composition and process for preparing the same
Inventor: VLADULESCU CONSTANTIN MARIUS
IPC: A01N27/00
Filed: 2012-11-27
Abstract: The invention relates to an agricultural additive composition which is meant for increasing the performances of the agricultural-chemical products applied by spraying, said composition being added to the mixtures carried out in the tank of the treatment equipments, and to a process for preparing said composition. The claimed composition comprises 42.1...54.8 parts of ethyl esters of rape or sunflower oil fatty acids or 64.1 parts of methyl esters of soybean oil fatty acids, 10.1...17.0 parts of ethyl alcohol, 3.9...6.4 parts of glycerol, 2.5...4.4 parts of triglycerides, 10.4...30 parts of emulsifiers, represented by liquid soybean lecithin and liquid soybean lecithin and MOA-9, fatty alcohol ether with polyoxyethylene or ammonium lauryl sulphate, possibly 1.2 parts of potassium hydroxide, or 0.95 parts of potassium acetate, or 6.4 parts of potassium oleate, 0.5...1.7 parts of water, non-saponifiable substances and fatty acid salts or free fatty acids and salts for the remainder, up to 100 units. The claimed process consists in using alcohol in excess in a trans-esterification reaction, while maintaining the trans-esterification reaction products and the excess of ethyl alcohol or while adding ethyl alcohol and mixing with emulsifiers.
Patent RO-133574-A0 (RO)
Title: Device for fuel-containing enclosure
Inventor: MĂTĂSARU IOSIF
IPC: F24H1/43
Filed: 2019-04-17
Abstract: The invention relates to a device for a fuel-containing enclosure, such as a stove, a thermal power station or a furnace. According to the invention, the device consists of a top element (T2) open at both ends, which is partially located inside a bottom element (T1) open at the top and closed at the bottom, both being mounted inside the combustion enclosure by means of some profiles (P4 and P5), and providing control of hot gas (3) circulation, control which is performed by virtue of the fluid mechanics laws.