baber/WOPTO huggingface dataset:
Patent DE-60320265-T2 (DE)
Inventor: COURTIN OLIVIER
IPC: A61Q19/08
Filed: 2003-07-08
Granted: 2009-05-14
Abstract: The invention concerns a cosmetic composition containing a Diospyros kaki extract and a Pueraria lobata extract. The invention also concerns the use of said composition for preventing and/or for fighting against skin ageing.
Patent DE-68922577-T2 (DE)
Inventor: JANSSEN CORNELUS GERARDUS MARI
IPC: A61P43/00
Filed: 1989-10-30
Granted: 1995-09-28
Abstract: Novel 3-piperidinyl-1,2-benzisoxazoles of formula <CHEM>  wherein Alk is C1-4alkanediyl;  R<1> is hydrogen, C1-4alkyl or halo;  R<2> is C1-4alkyl;  R<3> is hydroxy or R<4>-C(=O)O-; and  R<4> is C1-19alkyl; the pharmaceutically acceptable acid addition salts and stereoisomers thereof, which compounds are anti-psychotic agents; pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.
Patent DE-68924347-T2 (DE)
Inventor: MATSON STEPHEN
IPC: C07C327/32
Filed: 1989-04-06
Granted: 1996-03-28
Abstract: This invention relates to novel compositions of matter and their methods of preparation, which compositions are esters with enhanced water solubility, for use in aqueous enzymatic resolution reactions of racemic mixtures of these esters. The importance of the production of the separate chiral isomers of the racemic mixtures resides in the isolation of the isomers which frequently have different biological activities. Of particular significance regarding the water soluble esters of this invention is that they are derivatized with groups which enhance their aqueous solubility and their reactivity with this invention's novel enzymatic resolving methods which are mediated in an aqueous environment.
Patent DE-68925103-T2 (DE)
Inventor: GOLDSTEIN FREDERIC
IPC: B26B27/00
Filed: 1989-05-18
Granted: 1996-06-05
Abstract: A tool for curling gift-wrapping ribbon has two arms which are pivotally mounted at one end and have a pad and blade at the other end. Closing the arms clamps a ribbon between the pad and blade and the tool can then be drawn along the ribbon to produce a curled effect.
Patent DE-69002011-T2 (DE)
Inventor: PERRIN CLAUDE
IPC: C07B61/00
Filed: 1990-01-16
Granted: 1993-12-23
Abstract: The invention relates to the field of organic chemistry, and more specifically to the synthesis of phenylpropionic acids. Its specific subject is a new process for the preparation of 2-[4-(R-amino)phenyl]propionic acids of general formula I <IMAGE> which consists in subjecting a 2-(4-aminophenyl)propionic derivative of formula II <IMAGE> in which R1 is hydrogen or a C1-C6 alkyl radical, to the action of an alkylating agent in a heterogeneous phase in the presence of a phase transfer catalyst and a basic agent in an aqueous medium. The acids obtained are active principles of medicaments.
Patent DE-69006010-T2 (DE)
Inventor: CALVIN SOEREN
IPC: B31B50/20
Filed: 1990-01-17
Granted: 1994-07-07
Abstract: PCT No. PCT/SE90/00040 Sec. 371 Date Jul. 5, 1991 Sec. 102(e) Date Jul. 5, 1991 PCT Filed Jan. 17, 1990 PCT Pub. No. WO90/08018 PCT Pub. Date Jul. 26, 1990.A process and an apparatus for preventing a packaging material which is being die-cut and scored from developing cracks. A crack-reducing sheet material (17) is positioned between the cutting/scoring tools (9, 13) and the packaging material (5) to absorb impact energy from said tools and relieve the packaging material of crackproducing forces in the direction of its plane.
Patent DE-69007026-T2 (DE)
Inventor: GUEYDAN HENRI
IPC: F16D1/12
Filed: 1990-11-15
Granted: 1994-06-23
Abstract: The subject of the invention is an adjustable pulley (1) comprising a ring (2) and a hub (14) to which is fixed the shaft, which is adjustable about the axis of rotation with respect to this ring (2), which last is improved by the presence of means of adjustment about the axis of rotation of the hub (14) with respect to the ring (2) comprising teeth (11) on the ring (2) and a pinion (23) which anchors itself to the hub (40) at a fixed position (22), the pinion (23) then co-operating with the teeth (11) and producing a continuous and reproducible rotation of the hub (14) with respect to the ring (2). The invention applies particularly to the adjusting of the orientation of a shaft used to control an automotive part, for example a camshaft controlling an injection pump. <IMAGE>
Patent DE-69011363-T2 (DE)
Inventor: WAGENKNECHT MARCEL
IPC: A61B17/60
Filed: 1990-02-09
Granted: 1994-12-15
Abstract: This external fixator for the correction and reduction of fragments of bone comprises a bar (1) solidly fixed to a biocompression system (5) on which are placed the supports (2, 3) for fixing pins inserted in the bones, the elements of which can be moved in the direction of the arrows A, B, C and D. The member (6) permits the longitudinal displacement of the flange (2) in the direction of the arrow E, while the biocompression system (5) provides a reciprocal movement in the direction of the arrow F. A damping element (90, 290) interacts with means for adjusting the force applied, these means being external to the bar. Graduated reference marks (99, 283) indicate the value of the force applied. <IMAGE>
Patent DE-69012264-T2 (DE)
Inventor: MARTORANO RICHARD
IPC: C04B41/48
Filed: 1990-10-04
Granted: 1995-01-12
Abstract: A method for coating a substrate with an ambient-temperature-drying aqueous elastomeric coating composition is provided. The composition comprises at least two mutually incompatible water-insoluble polymers, with at least one of the polymers comprising N-methylol functionality. The coating composition may be used for high gloss elastomeric wall coatings or for sports surface coatings.
Patent DE-69017236-T2 (DE)
Inventor: SCHLAEPPI JEAN-MARC DR
IPC: A61K31/00
Filed: 1990-01-16
Granted: 1995-07-20
Abstract: The invention concerns a process for the preparation of hybridoma cells which secrete monoclonal antibodies specific for hirudin, the hybridoma cells themselves, the monoclonal antibodies specific for hirudin secreted by these hybridoma cells, derivatives thereof, and a process for the preparation of said antibodies and derivatives. These monoclonal anti-hirudin antibodies and their derivatives are useful for the determination of hirudin and as an antidote to hirudin. The invention also concerns test kits and pharmaceutical compositions comprising said monoclonal antibodies and/or derivatives.
Patent DE-69110089-T2 (DE)
Inventor: LEGROS RAYMOND DONALD
IPC: F01D5/12
Filed: 1991-06-10
Granted: 1995-11-02
Abstract: A method of repairing rotor blades on a turbine comprises the steps of removal of a rotor (12) from the turbine, selecting a predetermined desired position of the blades and, after removing any inter blade ties (66,67) necessary to enable any required repair processes to be carried out, aligning all the blades (60,61,62,63) to said predetermined aligned position prior to the carrying out of any repair step which may incorporate cutting, welding, machining etc., such alignment considerably facilitates semi-automated repair of each blade (60,61,62,63) and has further benefits in facilitating reinsertion of inter blade ties (66,67) and ensuring that the blades (60,61,62,63) are not only in an aligned position but in a stress free condition when returned to the turbine. <IMAGE>
Patent DE-69112039-T2 (DE)
Inventor: NAPPIER THOMAS
IPC: C07C53/126
Filed: 1991-11-22
Granted: 1996-01-11
Abstract: Gold carboxylates and a process for preparing gold salts of organic carboxylic acids are described. The gold carboxylates are represented by the formula   <IMAGE> (I)  in which R represents hydrogen or an organic group of valence y and x, y and z each represent a positive integer such that x=y.z/3. The process comprises reacting an alkali or alkaline earth metal salt of an organic carboxylic acid with a gold salt in an organic liquid which at least partially dissolves the alkali and/or alkaline earth metal salt, the gold salt, and the desired gold carboxylate product, but is not a solvent for the salt formed between the alkali or alkaline earth metal and the anion of the gold salt.
Patent DE-69123145-T2 (DE)
Inventor: TREMBLAY PAUL
IPC: C12P7/64
Filed: 1991-04-16
Granted: 1997-06-12
Abstract: The present invention relates to a process for forming a soluble monovalent salt of a phosphatidyl ester which comprises :   a) reacting a phospholipid with a primary alcohol in the presence of ;     i) an enzyme catalyst phospholipase D ;   ii) a divalent cationic buffer solution and iii) a water immiscible non-ether solvent so as to form the corresponding phosphatide of the divalent cationic salt; and   b) converting the divalent cationic salt to an organic soluble monovalent salt by suspending with a stoichiometric amount of a monovalent salt having a monovalent cation and whose anion forms an insoluble precipitate with the divalent cation.
Patent DE-69130893-T2 (DE)
Inventor: RITTERSHAUS CHARLES
IPC: G01N33/577
Filed: 1991-11-01
Granted: 1999-07-01
Abstract: The present invention is directed to the measurement of soluble leukocyte surface markers, soluble T cell growth factor receptors, soluble complement receptors, soluble T cell differentiation antigens, or related soluble molecules or fragments thereof, and the use of such measurements in the diagnosis and therapy of diseases and disorders. The invention is also directed to the measurement of soluble CD35 (sCD35) or fragments thereof, and the use of such measurements in detecting disease or disorders. A polyclonal sandwich assay is provided for the detection and/or measurement of soluble CD35. The invention further relates to the measurement of total leukocyte markers or fragments thereof, and the use of such measurements in the detection and diagnosis of diseases or disorders. The term "total" leukocyte marker used herein refers to the total amount of a leukocyte marker in a sample, including that present in membrane and intracellular compartments and extracellular soluble compartments. Measurements of a total leukocyte marker can be used to determine the approximate amount in a body fluid sample of leukocytes positive for the leukocyte marker. In a further embodiment, the invention relates to the measurement of both the amount of total leukocyte marker and the amount of the soluble form of the leukocyte marker and a comparison of the measured levels.
Patent DE-69203593-T2 (DE)
Inventor: FAVREAU JEAN
IPC: A01K23/00
Filed: 1992-03-06
Granted: 1996-01-04
Abstract: The invention relates to a toilet for dogs and cats, of the open type, comprising a substantially planar and horizontal part (2) for the animal to stand in, a vertical part (3) secured to the said horizontal part, rinsing means connected up to a water inlet (10) and a system (13) for evacuating the waste water, a litter reservoir (6) and its metering system for depositing some of the said litter on the horizontal part, and at least one cell (4, 5) for detecting the presence of the animal on the said horizontal part, commanding, once the animal has left the horizontal plane the sequence of rinsing and restocking with litter, the rinsing means consisting of a water inlet boom (9) on the bottom of the vertical part and the system for evacuating the waste water being of the siphon type including, on the bottom part of the siphon, an additional rinsing water inlet. <IMAGE>
Patent DE-69203950-T2 (DE)
Inventor: MORGAN ROBIN WILSON
IPC: C07K16/00
Filed: 1992-05-13
Granted: 1995-12-21
Abstract: The invention is related to a nucleic acid sequence encoding a MD06 Marek's Disease Virus protein. Such a protein can be used for the immunization of poultry against MDV infection or disease. The nucleic acid sequence encoding the MD06 MDV protein can be applied for the preparation of the protein by means of genetic engineering techniques or can be applied for the preparation of vector vaccines.
Patent DE-69206369-T2 (DE)
Inventor: MERENDA MICHELE
IPC: C08K5/14
Filed: 1992-09-14
Granted: 1996-09-12
Abstract: Liquid peroxidic compositions essentially constituted by the following components per 100 parts by weight of compositions:   from 65 to 95 parts by weight of bis(alpha-t-amyl-peroxyisopropyl)-benzene (I), the two substituents being in meta and/or para position with respect to the benzenic ring, the meta/para ratio ranging preferably between 1 and 2; and from 5 to 35 parts by weight of bis(alpha-t-butyl-peroxyisopropyl)-benzene (II), the two substituents being in meta and/or para position with respect to the benzenic ring, the meta/para ratio ranging preferably between 1.5 and 2; the para (1)/para (II) and meta (I)/para (II) composition being excluded. l
Patent DE-69212681-T2 (DE)
Inventor: BOUILLOUX ALAIN
IPC: C08J5/18
Filed: 1992-03-17
Granted: 1997-01-02
Abstract: Polymer film made from a polyamide/polyolefin alloy for the manufacture of a sheet compounding product, characterised in that it comprises the components A, B, C and D according to the following percentages by weight:  30 </= A + B + C </= 60      0 </= A </= 60  and  B + C >/= 1      where 0 </= B </= 60  and  A + B + C + D = 100      where 0 </= C </= 60; the said components A, B, C and D having the following compositions:     A consists of at least one polyolefin composed of a partially or completely linear alpha-olefin; B represents the alpha-olefin described in A on which one or two functionalised monomers have been grafted; C is a grafted copolymer consisting of at least one monoaminated polyamide oligomer and of an alpha-monoolefin polymer or copolymer grafted by a monomer capable of reacting with the amine function of the said monoaminated oligomer;   D consists of at least one aliphatic (co)polyamide. t
Patent DE-69212832-T2 (DE)
Inventor: WOLLER STEEN
IPC: E02D7/16
Filed: 1992-07-02
Granted: 1997-03-20
Abstract: The machine comprises a mobile, self-propelled frame (1), which carries a mast (7) with a driving head, which either by means of a chain and a hydraulic motor (48) may be pulled down towards the foot of the mast, or by means of a hydraulic jack may be driven towards the foot of the mast. A pile placed under the driving head may thereby be pulled or driven into the ground. The mast may be pivoted in the longitudinal direction of the machine, tilted transversely thereto, displaced transversely to the machine and displaced from the centre of the machine to the front of the machine, which ensures a correct positioning of the pile without the whole machine having to be moved. The mast may carry a displaceable holder, which prevents the pile from bending during the driving down, and a measuring cell for the measurement of the piling force applied may be placed in the driving head (30).
Patent DE-69226708-T2 (DE)
Inventor: KYLE DONALD
IPC: A61P17/02
Filed: 1992-04-16
Granted: 1999-04-15
Abstract: The substitution of the L-Pro at the 7-position with D-Phe or D-Tic and substitution of the L-Phe at the 8-position with hydroxyproline ethers and thioethers of the peptide hormone bradykinin and other additional substituted analogs of bradykinin converts bradykinin agonists into bradykinin antagonists. The invention further includes additional modifications at other positions within the novel 7- and 8-position modified bradykinin antagonists, which increase enzyme resistance, antagonist potency, and/or specificity of the new bradykinin antagonists. The analogs produced are useful in treating conditions and diseases of a mammal and human in which an excess of bradykinin or related kinins are produced or injected as by insect bites.
Patent DE-69226990-T2 (DE)
Inventor: LINDHOLM LEIF
IPC: C07K16/00
Filed: 1992-07-03
Granted: 1999-03-25
Abstract: A monoclonal antibody that reacts with the CA-242 antigen is provided. The antibody can be obtained by culturing the hybridoma cell line C242:II with the ECACC identification number 90012601, or an artificial or spontaneous mutant thereof. Cell lines producing the antibody are also provided. The antibody is useful for therapeutic and diagnostic purposes.
Patent DE-69229442-T2 (DE)
Inventor: HALLINAN E
IPC: C07D413/04
Filed: 1992-04-16
Granted: 1999-10-28
Abstract: The present invention provides dibenzoxazepine compounds of Formula I: <CHEM> which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Patent DE-69233479-T2 (DE)
Inventor: GOLDIN STANLEY M
IPC: A61K31/445
Filed: 1992-02-10
Granted: 2006-03-16
Abstract: Modulators of neurotransmitter release including substituted guanidines, N''-aminoguanidines, and N,N',N'',N'''-tetra-substituted hydrazinedicarboximidamides, and pharmaceutical compositions thereof are disclosed. Also disclosed are methods involving the use of such neurotransmitter release modulators for the treatment or prevention of pathophysiologic conditions characterized by the release of excessive or inappropriate levels of neurotransmitters. Also disclosed are screening assays for compounds which selectively inhibit glutamate release. Also disclosed are methods of blocking voltage sensitive sodium and calcium channels in mammalian nerve cells.
Patent DE-69308949-T2 (DE)
Inventor: PHELIPON AXEL
IPC: A63C5/075
Filed: 1993-01-22
Granted: 1997-08-28
Abstract: Ski (1) equipped with at least one shock-absorbing device intended to dampen the vibrations of a ski, characterised in that it consists of at least one flexion blade (13) which comprises a first part (131) fastened rigidly to the ski and a second part (130) connected to the ski in a movable manner longitudinally by shock-absorbing means (14) of the type with viscous friction. <IMAGE>
Patent DE-69309685-T2 (DE)
Inventor: BARNEA EFRACH
IPC: A61P15/00
Filed: 1993-07-09
Granted: 1997-10-16
Abstract: A two component fibrin-glue composition comprising the components A and B, wherein component A comprises fibrinogen and a protease inhibitor, component B comprises a proteolytic enzyme being capable of cleaving specifically fibrinogen and causing formation of the fibrin polymer and additionally ingredients for culturing embryonic cells of mammals in one or both of the components A and B.
Patent DE-69317600-T2 (DE)
Inventor: SANDOZ JEAN-LUC
IPC: E04C3/14
Filed: 1993-06-15
Granted: 1998-07-09
Abstract: It is characterised in that:   - it comprises at least two assemblies (1, 2) which each consist of a laminated and glued layer formed by slats of rectangular cross-section which are juxtaposed side by side without being offset in relation to one another; - it has a structure which is such that, if a bending force is considered to be exerted on the upper part of the said material, at least the outer layer (lower layer) subjected to the greatest tensioning during this bending stress is formed by slats (2) glued to each other in the vertical direction (direction of bending) against the lower surface of the layer which is adjacent to it.   <IMAGE>
Patent DE-69319303-T2 (DE)
Inventor: LUCAERI THOMAS
IPC: A61F13/56
Filed: 1993-10-14
Granted: 1998-10-22
Abstract: A disposable panty shield (10) comprising a thin, highly absorbent pad having a body-contacting surface (12), an absorbent layer (16), a liquid barrier (17), a positioning means (18) for attaching the pad to an undergarment, and a release layer (19) to protect the positioning means prior to use wherein the entire structure has been densified by fusing all pad layers together in a manner such that the interstitial space between the individual fibers in the densified areas (13,14) is not sufficient to readily allow fluid to flow through. Further, the densified areas are made contiguous such that fluid, when introduced or deposited on the pad, will be prevented or hindered from flowing to the edges of the pad (10). <IMAGE>
Patent DE-69319591-T2 (DE)
Inventor: WILLIAMS DENNIS COLIN
IPC: C23F11/12
Filed: 1993-01-22
Granted: 1998-11-12
Abstract: PCT No. PCT/GB93/00139 Sec. 371 Date Jan. 4, 1995 Sec. 102(e) Date Jan. 4, 1995 PCT Filed Jan. 22, 1993 PCT Pub. No. WO94/17221 PCT Pub. Date Aug. 4, 1994A chemical formulation and method are provided for the treatment of water to prevent, control or inhibit corrosion and/or deposits, particularly for the treatment of water in water distribution piping and equipment and associated heat exchangers and more particularly for the treatment of water in heat transfer equipment wherein water or steam is employed as the heat transfer medium. The method treats the water with at least one mono- or polyhydric alcohol. Optionally, the treatment formulation is a blend of mono- or polyhydric alcohols and further optionally includes one or more of a mixed molecular weight polyacrylic acid and/or at least one salt thereof; at least one chromium-free lignosulfonate, and at least one carboxylic acid and/or at least one salt thereof, the carboxylic acid being different from the poly acrylic acid.
Patent DE-69323866-T2 (DE)
Inventor: BANKS BERNARD JOSEPH
IPC: A23K20/195
Filed: 1993-01-11
Granted: 1999-07-01
Abstract: Compounds of formula (I) wherein R<1> is C1-C6 alkyl, C3-C6 alkenyl, or substituted C1-C4 alkyl wherein said substituent is halo, C1-C4 alkoxy, C2-C5 alkanoyl, C2-C5 alkoxycarbonyl, carboxy, mercapto or aryl; R<2> is C3-C8 alkyl, C3-C8 alkenyl, C3-C8 cycloalkyl or C5-C8 cycloalkenyl; R<3> is OH, C1-C4 alkoxy or C2-C5 alkanoyloxy; or R<3> is linked by a double bond and is =N-OR<5> wherein R<5> is H, C1-C4 alkyl or C2-C5 alkanoyl; and R<4> is HO, C1-C4 alkoxy, C2-C5 alkanoyloxy or halo; or R<4> is linked by a double bond and is =O or =N-OR<5>; or R<4> is a group of formula (II) wherein R<6> is HO, C1-C4 alkoxy, C2-C5 alkanoyloxy or halo, or R<6> is linked by a double bond and is =O or =N-OR<5>; with certain provisos when R<2> is isopropyl or sec-butyl; are broad spectrum antiparasitic agents useful for treating parasite infestations of livestock and domesticated animals.
Patent DE-69330297-T2 (DE)
Inventor: HANAI NOBUO
IPC: C12N15/09
Filed: 1993-06-25
Granted: 2002-05-02
Abstract: This invention relates to monoclonal antibodies capable of specifically reacting with a peptide encoded by tumor suppressor gene DCC gene and to hybridomas capable of producing such monoclonal antibodies. In particular, the invention relates to mouse monoclonal antibody KM890 belonging to the IgG3 subclass, which is specifically reactive with a DCC gene DCC-2, and to a hybridoma KM890 capable of producing the monoclonal antibody KM890. The monoclonal antibodies of this invention which are specifically reactive with DCC gene products can be used in immunohistochemical staining, quantitative determination of DCC gene products and the like, as well as in cancer diagnosis.
Patent DE-69402837-T2 (DE)
Inventor: EMMONS DAVID
IPC: G02B6/42
Filed: 1994-01-07
Granted: 1997-07-31
Abstract: A patch cord includes a cable having a primary transmission member contained within a protective sheathing. An energy transmission member is carried on the cable and extends from a first end to a second end. First and second couplings are connected to the first and second ends of the energy transmission member. The first coupling receives energy from an external source and transmits the energy along the energy transmission member toward the second coupling. The second coupling receives energy from the energy transmission member and generates a visible signal in response to the received energy.