Patent SG-11201908512Y-A (SG)
Title: Somatostatin modulators and uses thereof
Inventor: HAN SANGDON
IPC: A61P35/00
Filed: 2018-03-15
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 20 September 2018 (20.09.2018) WIPO I PCT omit °nolo mourn° oimIE (10) International Publication Number WO 2018/170284 Al (51) International Patent Classification: CO7D 401/14 (2006.01) A61P 25/00 (2006.01) A61K 31/4545 (2006.01) A61P 35/00 (2006.01) A61K 31/4184 (2006.01) A61P 27/02 (2006.01) (21) International Application Number: PCT/US2018/022665 (22) International Filing Date: 15 March 2018 (15.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/472,480 16 March 2017 (16.03.2017) US (71) Applicant: CRINETICS PHARMACEUTICALS, INC. [US/US]; 6197 Cornerstone Court, Suite 111, San Diego, California 92121 (US). (72) Inventors: HAN, Sangdon; 6197 Cornerstone Court, Suite 111, San Diego, California 92121 (US). KIM, Sun Hee; 6197 Cornerstone Court, Suite 111, San Diego, California 92121 (US). ZHU, Yunfei; 6197 Cornerstone Court, Suite 111, San Diego, California 92121 (US). (74) Agent: ZUNIC, Valentin B.; WILSON SONSINI GOODRICH & ROSATI, 650 Page Mill Road, Palo Alto, California 94304 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. = (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, 1-1 TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). 71- 00 C•1 O N 1-1 Declarations under Rule 4.17: as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(ii)) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: — with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) 00 (54) Title: SOMATOSTATIN MODULATORS AND USES THEREOF 1-1 <= (57) : Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical \" compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, 0 diseases, or disorders that would benefit from modulation of somatostatin activity.