baber/WOPTO huggingface dataset:
Patent CA-2372746-C (CA)
Title: Imidazolidine-based metal carbene metathesis catalysts
Inventor: GRUBBS ROBERT H
IPC: C07B61/00
Filed: 2000-05-22
Granted: 2012-10-02
Abstract: The present invention relates to novel metathesis catalysts with an imidazolidine-based ligand and to methods for making and using the same. The inventive catalysts are of formula (I) wherein : M is ruthemium or osmium; X  and X1 are each independently an anionic ligand; L is a neutral electron donor ligand; and, R, R1, R6, R7, R8 and R9 are each independently hydrogen or a substituent selected from the group consisting of C1-C20 alkyl, C2-C20 alkenyl, C2-C20 alkynyl, aryl, C1-C20 carboxylate, C1-C20 alkoxy, C2-C20 alkenyloxy, C2-C20 alkynyloxy, aryloxy, C2-C20 alkoxycarbonyl, C1-C20 alkylthiol, aryl thiol, C1-C20 alkylsulfonyl and C1-C20 alkylsulfinyl, the substituent optionally substituted with one or more moieties selected from the group consisting of C1-C10 alkyl, C1-C10 alkoxy, aryl, and a functional group selected from the group consisting of hydroxyl, thiol thioether, ketone, aldehyde, ester, ether, amine, imine, amide, nitro, carboxylic acid, disulfide, carbonate, isocyanate, carbodiimide, carboalkoxy, carbamate, and halogen. The inclusion of an imidazolidine ligand to the previously described ruthenium or osmium catalysts has been found to dramatically improve the properties of theses complexes. The inventive catalysts maintains the functional group tolerance of previously described ruthenium complexes while having enhanced metathesis activity that compares favorably to prior art tungsten and molybdenum systems.
Patent CA-2374767-C (CA)
Inventor: LEE JIN SOO
IPC: C07D471/04
Filed: 2000-05-18
Granted: 2007-05-15
Abstract: La présente invention concerne des dérivés d'acide quinoléine-carboxylique actifs optiquement, leur sels et solvates acceptables sur le plan pharmaceutique, ainsi qu'un procédé permettant leur préparation. Plus particulièrement, la présente invention concerne des dérivés d'acide quinoléine-carboxylique actifs optiquement ayant des substituts 4-aminométhyl-4-méthyl-3-(Z)-alcoxyiminopyrrolidine provoquant une activité optique dans la position 7 de la quinolone. Etant donné que les composés de la présente invention présentent une activité antibactérienne supérieure à celle de leurs énantiomères, des mélanges racémiques de ceux-ci et d'autres agents antibactériens présentent une bonne caractéristique pharmacocinétique sans comporter de phototoxicité, le composé de cette invention s'avérant utile pour un agent antibactérien.
Patent CA-2376835-C (CA)
Inventor: NAITO TOSHIHIKO
IPC: C07D473/00
Filed: 2000-06-30
Granted: 2009-09-15
Abstract: La présente invention concerne de nouveaux composés imidazole fusionnés représentés par la formule générale (I), certains de leurs sels, hydrates ou ensemble des deux, pharmacologiquement acceptables. Ces composés, qui font preuve d'antagonisme pour le récepteur A2 de l'adénosine, sont indiqués pour la prévention et le traitement du diabète sucré et des complications des diabètes. Dans cette formule, R<1> est amino éventuellement alkylé ou analogue, R<2> est hydrogène, alkyle ou analogue, R<3> est un aryle éventuellement substitué, un groupe pyridinone, un groupe pyrimidinone ou analogue, Ar est un groupe aryle ou hétéroaryle éventuellement substitué, ou analogue, et A et W sont chacun indépendamment N ou CH.
Patent CA-2382302-C (CA)
Title: A nucleic acid and encoding polypeptide for use in inhibiting tumor angiogenesis
Inventor: PENNICA DIANE
IPC: C12N9/00
Filed: 1998-09-16
Granted: 2009-07-14
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptides molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Patent CA-2390922-C (CA)
Inventor: GRINNELL CHARLES M
IPC: A61B17/00
Filed: 2000-11-01
Granted: 2009-10-13
Abstract: L'invention concerne un instrument chirurgical et une technique destinés à l'endartériectomie. Cet instrument possède une tige ayant une extrémité distale et une extrémité proximale, une tête (80) étant accouplée à l'extrémité distale de la tige (82) et un manche étant accouplé à l'extrémité proximale. Cette tête possède un orifice (86) d'endoscope et au moins un orifice fluidique (84), le manche comportant un orifice d'alimentation en gaz et une vanne d'écoulement permettant de mesurer le débit gazeux entre l'orifice d'alimentation en gaz et ledit orifice fluidique situé sur la tête, ainsi qu'un verrou servant à retenir la tête d'un endoscope. Le gaz peut être acheminé vers la tête depuis le manche dans une lumière séparée de celle qui contient l'endoscope.
Patent CA-2393150-C (CA)
Title: Connecting assembly for spinal osteosynthesis
Inventor: PETIT DOMINIQUE
IPC: A61B17/70
Filed: 2000-12-01
Granted: 2008-11-18
Abstract: The invention concerns a connecting assembly for spinal osteosynthesis comprising a bone anchoring element including a connection zone (29) designed to co-operate with a connecting means. The invention is characterised in that the connecting means comprises in its lower part a spherical shape (20) designed to enable the connecting means to be freely positioned in a connector (8) or in a linking element (3) having a cavity with matching shape, said spherical shape (20) forming a stop element for longitudinal positioning with the connector (8) or with the linking element (3).
Patent CA-2396625-C (CA)
Inventor: STREET DOUGLAS
IPC: B60R13/01
Filed: 2002-08-02
Granted: 2006-12-12
Abstract: A multi-functional cargo bed liner assembly for a cargo bed of a vehicle includes a first and a second side wall disposed in a transversely spaced relationship, and an integrally formed guide track in the first and second side walls. The cargo bed liner assembly also includes an end wall extending therebetween the first and second side wall at a first end,  and a floor extending therebetween the first and second side walls. The cargo bed liner assembly further includes a movable divider panel supported with the guide track by a support means, and extending transversely therebetween the first and second side walls, wherein the divider panel includes a positioning mechanism for fixedly locating the divider panel.
Patent CA-2400934-C (CA)
Title: Reverse link correlation filter in wireless communication systems
Inventor: ROUPHAEL ANTOINE J
IPC: H04B1/7093
Filed: 2001-02-23
Granted: 2011-04-05
Abstract: A single, common correlation filter (CF) core is provided in a wireless system using CDMA (code division multiple access). A plurality of channels with different data rates are provided in the wireless system. The channels provided in the wireless system include the access channel, the maintenance channel, and the traffic channel in which information (e.g., pilot or data symbols or both) is transmitted at the tier 1 (which is the basic despreading rate), tier 2 and tier 3 rates. The data rate for transmitting the information is programmable by an external programmable processor, e.g., a digital signal processor (DSP). A user-unique code, such as a PN (pseudo-random noise) code, is applied to the information being transmitted in the channels of the wireless system. Theinformation is modulated and transmitted in any one of the channels at any data rate. The transmitted information is correlated at the basic despreading rate (i.e., the tier 1 rate) in the correlation filter (CF) of the wireless system by time multiplexing delayed versions of the PN code (or orthogonal code, Walsh code) to the correlation filter core. The correlated information is then demultiplexed and demodulated. The demodulated information is summed at the proper integer multiple of the tier 1 rate to achieve the tier 2 and tier 3 rates. One or more signal components are selected (in terms of the received power, signal-to-noise ratio or multipath width) in a window or time period for optimal information recovery. The selecting step can also be implemented according to a preprogrammed time alignment. Furthermore, outputs from the demodulated information can be provided and combined for temporal diversity. Spatial diversity is achieved by providing a plurality of antennas, and a plurality of receivers at a location and providing a single, common correlation filter at each of the plurality of antennas of the receivers in the wireless system.
Patent CA-2401625-C (CA)
Inventor: SHAO RICHARD LIICHANG
IPC: C01B31/04
Filed: 2001-02-20
Granted: 2008-09-09
Abstract: A process for preparing pins for connecting carbon electrodes is presented. In particular, a process for preparing pins for connecting carbon electrodes including the steps of combining calcined coke, a liquid pitch binder and carbon fibers derived from mesophase pitch to form a pinstock blend; extruding the pinstock blend to form a green pinstock; baking the green pinstock to form a carbonized pinstock; and graphitizing the carbonized pinstock by maintaining the carbonized pinstock at a temperature of at least about 2500 .degree.C for no more than about 18 hours is presented. The pins prepared by the inventive process are also presented.
Patent CA-2413679-C (CA)
Inventor: STEPHEN JAMES C
IPC: F17C13/08
Filed: 2002-12-09
Granted: 2008-03-04
Abstract: The present invention provides a support apparatus for a fuel tank used in connection with a gas barbecue grill assembly. The support apparatus is connected to a portion of the frame assembly of the grill assembly. The support apparatus comprises a housing member with a bracket adapted to engage a portion of the fuel tank and a releasable member operably connected to the housing member. At least one pivot axis member operably connects the support apparatus to a portion of the frame assembly. The support apparatus is rotatable about a generally vertical axis between a first position wherein the fuel tank is substantially within the frame assembly and stored for use, and a second position wherein the fuel tank is substantially beyond the frame assembly and accessible for removal and replacement. The releasable member is adapted to secure the support apparatus in either the first position or the second position.
Patent CA-2430468-C (CA)
Inventor: LUNDTORP KASPER
IPC: B09B3/00
Filed: 2001-12-19
Granted: 2008-11-04
Abstract: La présente invention concerne un procédé qui permet de réduire la lixiviation des éléments formant des oxyanions, en particulier le chrome, présents dans des matières contenant des constituants nocifs pour l'environnement, en particulier dans des résidus d'incinération, en particulier dans des produits de l'épuration des gaz de combustion provenant de l'incinération des déchets, en particulier dans des cendres volantes, les matières précitées étant mélangées à un milieu aqueux tel que de l'eau dans un conteneur fermé selon un rapport liquide-solide suffisant pour provoquer les conditions de réduction capables de stabiliser les éléments formant les oxyanions, en particulier le chrome, en raison de l'oxydation de l'Al, du Zn, du Fe métalliques et d'autres métaux libres présents dans lesdites matières.
Patent CA-2431617-C (CA)
Title: 7-heterocyclyl quinoline and thieno[2,3-b]pyridine derivatives useful as antagonists of gonadotropin releasing hormone
Inventor: SUI ZHIHUA
IPC: C07D215/22
Filed: 2001-12-11
Granted: 2011-07-12
Abstract: The present invention is directed to novel 7-heterocyclyl quinoline and thieno[2,3-b]pyridine derivatives of the general formula (I) or (II), wherein all variables are as herein defined, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions associated with gonadotropin releasing hormone (GnRH). The compounds of the invention are antagonists of GnRH, useful in the treatment of the infertility, prostate cancer, benign prostate hyperplasia (BPH) and as contraceptives.
Patent CA-2431680-C (CA)
Title: Fish tape having a thumb winder
Inventor: KONEN BRUCE P
IPC: H02G1/08
Filed: 2003-06-10
Granted: 2012-08-14
Abstract: A fish tape assembly includes a generally circular case, a fish tape and a winder. The fish tape has an inner end, an outer end and a main section. The inner end is fastened in the interior of the case to an anchor and an eyelet is formed at the outer end. A winder is slidable around the perimeter of the case. The toe of the winder is engageable with the fish tape to push it back into the case. A notch in the winder traps the eyelet to prevent the outer end of the tape from entering the case.
Patent CA-2435423-C (CA)
Title: Refrigerated extended shelf-life bread products
Inventor: TANGPRASERTCHAI URAIWAN
IPC: A21D8/02
Filed: 2003-07-16
Granted: 2011-05-31
Abstract: A fully baked bread product is provided which can be stored for extended periods of time and which retains its desirable soft texture for the shelf life (e.g., at least about 3 months) of the product if maintained under a modified atmosphere (i.e., low oxygen and preferably inert gas) at refrigerated conditions (i.e., about 35 to about 45°F). The fully baked bread is prepared from dough comprising, in baker's percentages, about 100 pounds flour, about 0.75 to about 3.5 pounds salt, about 0.2 to about 1 pounds microbial inhibitor, about 0 to about 3 pounds gluten, about 1 to about 5 pounds leavening agent, about 0.1 to about 1 pound enzyme, about 9 to 18 pounds high fructose corn syrup, about 3 to about 10 pounds shortening, about 0.1 to about 3 pounds mono- and diglycerides, and about 45 to about 60 pounds of water.
Patent CA-2437958-C (CA)
Inventor: ARNASON BARRY G W
IPC: A61P43/00
Filed: 2002-03-11
Granted: 2018-10-30
Abstract: The present invention concerns a family of nucleic acids, polypeptides and cloning vectors which direct expression of fusion proteins that can mimic aggregated IgG (AIG) and immune complex function with respect to their interactions with Fc.gamma.R and which allow for the inclusion and targeting of a second protein domain to cells expressing Fc.gamma.R. This was accomplished by expressing multiple linear copies of the hinge and CH2 domains (HCH2) of human IgG1 fused to the framework region of human IgG1. Convenient restriction sites allow for the facile introduction of additional amino-terminal domains. Methods for treating patients using fusion proteins are also disclosed. The HCH2 polymers described here represent a new strategy in the design of recombinant proteins for the therapeutic targeting of Fc.gamma.R in autoimmune disorders.
Patent CA-2445204-C (CA)
Inventor: RYAN WAYNE L
IPC: C12M1/24
Filed: 2003-10-16
Granted: 2014-08-12
Abstract: Le sujet matière revendiqué comprend un dispositif de prélèvement et de conservation de cellules comprenant : (1) un contenant de prélèvement comprend un tube doté d'une extrémité ouverte et d'une extrémité fermée, un mécanisme de fermeture dans l'extrémité ouverte du tube, un vide établi à un niveau prédéterminé à l'intérieur du contenant et (2) des composés comprenant un agent anticoagulant et un agent de fixation, dans lesquels les composés sont en quantité suffisante pour conserver la morphologie originale des cellules et des sites antigéniques sans dilution importante desdites cellules, et permettant ainsi auxdites cellules d'être directement analysées par un cytomètre en flux sans autre traitement. Le sujet matière revendiqué comprend une méthode de fabrication d'un dispositif de prélèvement pour cellules comprenant : (1) la fourniture d'un tube ayant une extrémité ouverte et une extrémité fermée; (2) le préchargement des composés comprenant un agent anticoagulant et un agent de fixation dans le tube, où les composés sont en quantité suffisante pour conserver la morphologie originale des cellules et les sites antigéniques sans dilution importante desdites cellules, et permettant ainsi aux cellules d'être directement analysées par un cytomètre en flux sans autre traitement; (3) l'insertion d'un mécanisme de fermeture dans l'extrémité ouverte du tube et (4) l'obtention d'un vide à l'intérieur du tube à un niveau prédéterminé pour former le dispositif de prélèvement.
Patent CA-2447565-C (CA)
Title: Ensemble et methode de verrouillage de moteur de fond
Inventor: DEWEY CHARLES H
IPC: E21B4/02
Filed: 2003-10-31
Granted: 2007-12-18
Abstract: Cet extrait concerne un moteur verrouillable qui est utilisable dans un trou de forage et se compose d'un stator, d'un rotor monté de façon à tourner dans le stator et d'un dispositif amovible de restriction de débit. Le moteur peut également être doté d'un dispositif servant à maintenir solidaires le rotor et le stator durant la rotation. Le dispositif de restriction de débit réduit le débit de liquide en aval du rotor, ce qui permet d'équilibrer la pression hydraulique au-dessus et en dessous du stator.
Patent CA-2448785-C (CA)
Title: Lockout for a rocker switch
Inventor: HENDERSON SHARMAINE
IPC: H01H23/26
Filed: 2003-11-10
Granted: 2012-02-14
Abstract: A switch lockout and rocker switch includes a switch cover, a rocker plate, a base, and a lockout slide. The rocker plate has apposite first and second ends, and is pivotally mounted to the cover. The rocker plate is thus pivotable about a pivot axis between oppositely tilted first and second tilted positions. The slide is selectively translatable relative to the base, being slidably mounted on the base for translation of the slide in a slide direction perpendicular to the pivot axis so as to slide relative to the rocker plate between a first lockout position and second lockout position.
Patent CA-2457642-C (CA)
Inventor: JOBSON RONALD
IPC: C07D477/20
Filed: 2002-09-20
Granted: 2009-01-06
Abstract: A process for preparing a crystalline, carbapenem monosodium salt of formula IIa, characterized by the steps a) adding about 10 to 30 % of an organic solvent to an aqueous solution of the carbapenem, b) cooling the resulting solution to less than -5 ~C, c) adjusting the pH using a solution containing an acid in an organic solvent to give the appropriate pH for crystallization, and d) crystallizing the compound by adding methanol, and a C2-5 alcohol at between -5 and -25 ~C.
Patent CA-2466099-C (CA)
Title: Composition containing feverfew extract and use thereof
Inventor: MARTIN KATHARINE M
IPC: A61Q19/08
Filed: 2003-09-08
Granted: 2012-03-20
Abstract: The present invention features a method for constricting blood vessels, inhibiting angiogenesis, and/or reducing non-inflammatory redness in the skin by the topical administration of a composition comprising a Feverfew extract.
Patent CA-2468567-C (CA)
Inventor: BUSAM EDWARD P
IPC: B42F13/04
Filed: 2004-05-27
Granted: 2009-03-10
Abstract: A system for storing index cards, the system including at least one storage sheet having at least one pocket, at least one supply sheet having at least one index card formed therein and detachable therefrom. The system further includes a binding mechanism that binds the storage sheet and the supply sheet together.
Patent CA-2469399-C (CA)
Title: Method and apparatus for assessing the status of work waiting for service
Inventor: FLOCKHART ANDREW D
IPC: H04M3/523
Filed: 2004-05-31
Granted: 2010-02-16
Abstract: The present invention provides a system and method for assessing the status of work waiting for service in a work queue or a work pool. Work items are placed in the work queue or work pool and have a service time goal. The work items in the work queue or work pool are scanned and a required queue position for each work item is calculated according to the amount of time remaining prior to the expiration of the service time goal and weighted advance time for servicing of work items in the work queue or pool. An array of counters has elements which correspond to required queue positions. Upon the calculation of the required queue position for a work item, the counter corresponding to the required queue position is incremented. When all of the work items are scanned, the array of counters is analyzed to predict a future state of the work queue or work pool.
Patent CA-2471573-C (CA)
Inventor: THEISS GUENTHER
IPC: G06Q10/10
Filed: 2002-12-27
Granted: 2016-09-27
Abstract: In certain embodiments, a system and method of receiving data indicates one or more software components included in a user's system landscape, receives a user's selection of a software component to be managed or customized, accesses the software component in response to the user's selection, receives a user's input relating to an alteration to be made to a feature or setting of the software component, and modifies one or more files associated with the software component to reflect the alteration.
Patent CA-2472355-C (CA)
Inventor: SMITH THOMAS W
IPC: B41J2/04
Filed: 1999-08-05
Granted: 2008-01-08
Abstract: A process which comprises: a) incorporating into an ink jet printing apparatus: a color forming composition comprising a liquid vehicle and at least one color forming agent, and a reacting composition comprising a liquid vehicle and at least one material capable of reacting with the color forming agent to cause a desired color to form; b) causing droplets of the color forming composition to be ejected in an imagewise pattern onto the substrate; and c) causing droplets of the reacting composition to be ejected in an imagewise pattern onto the substrate; wherein the process results in at least some portions of the substrate bearing images comprising both the color forming composition and the reacting composition, said portions forming a printed image, wherein one of i) the color forming composition and ii) the reacting composition is applied to the substrate in fixed volumes per pixel, and the other of i) and ii) is applied to the substrate in varying volume per pixel, thereby varying the intensity of color of the printed image.
Patent CA-2475704-C (CA)
Title: Colonic release formulations of prednisolone sodium metasulphobenzoate coated with amylose, ethyl cellulose and dibutyl sebacate
Inventor: PALMER RICHARD MICHAEL JOHN
IPC: A61K9/36
Filed: 2003-02-13
Granted: 2011-07-12
Abstract: The present invention relates to an improved controlled (preferably delayed) release formulation for delivery of prednisolone sodium metasulphobenzoate. The formulation comprises prednisolone sodium metasulphobenzoate surrounded by a coating comprising glassy amylose, ethyl cellulose and dibutyl sebacate, wherein the ratio of amylose to ethyl cellulose is from (1:3.5) to (1:4.5) and wherein the amylose is corn or maize amylose.
Patent CA-2477796-C (CA)
Title: Procede de reticulation de compositions d'asphalte et produit obtenu par ce procede
Inventor: RACHED MOISES CISNEROS
IPC: C08L95/00
Filed: 2003-02-11
Granted: 2011-04-19
Abstract: Cette invention porte sur un procédé de réticulation de compositions d'asphalte modifiées par polymères faisant appel à une combinaison d'un initiateur de réticulation, d'un co-agent de réticulation et d'un polymère réticulable, permettant ainsi d'obtenir un procédé à fiabilité et reproductibilité accrues qui génère des produits présentant une combinaison de propriétés supérieures à celles de compositions réticulées par le soufre classiques.