baber/WOPTO huggingface dataset:
Patent CA-2686216-A1 (CA)
Title: Vm23 and vm24, two scorpion peptides that block human t-lymphocyte potassium channels (sub-type kv1.3) with high selectivity and decrease the in vivo dth-responses in rats
Inventor: PANYI GYORGY
IPC: A61P37/06
Filed: 2007-05-14
Abstract: Potassium channels KvI.3 are known to be implicated in immunological diseases and graft rejections. Disclosed are peptides capable of blocking with high affinity and specificity potassium channels KvI.3, their pharmaceutical compositions, and methods for their use to block KvI .3 potassium channels, to treat various immunological conditions and to diagnostic applications. Methods for their chemical synthesis and correct folding are also disclosed. Exemplary peptides correspond to protein components (Vm23 and Vm24) isolated from the venom of the Mexican scorpion Vaejovis mexicanus smithi. Vm23 and Vm24 bind to hKvl.3 channels in an almost irreversible manner, showing a Kd value in the order of 3 picomolar range, when applied to human lymphocytes cultures in vitro. Vm24 was chemically synthesized and used in in vivo experiments to successfully treat sensitized rats (on the DTH-response). Neither Vm24 nor synthetic Vm24 is toxic to mice when injected at relatively high concentrations (assayed up to 10,000 micrograms per kilogram mouse body weight). These peptides (Vm24 and Vm23) and their functional equivalent analogs with at least 83% of sequence identity are lead compounds, candidates for the treatment of various immunological conditions and diagnostic applications.
Patent CA-2686251-A1 (CA)
Title: Rig control system architecture and method
Inventor: WINGKY MOCHAMMAD FAISAL
IPC: E21B44/00
Filed: 2009-11-24
Abstract: The present application discloses a method and framework for drilling rig supervisory control automation that includes replication and aggregation of drilling rig supervisory control panels, a mechanism to manipulate the supervisory control panel parameters using one or more smart algorithms and a method and technique to access the supervisory control panels from a remote location. The system and method further includes recording, editing, and playing back a drilling rig's supervisory control parameter sequence during any typical drilling rig operation. Such a sequence includes recording all of the actions involved in a specific operation of the drilling rig operator. This sequence is saved, and can be edited to optimize the sequence, and further played back on the rig from which it was recorded, or on any other rig in the network.
Patent CA-2686503-A1 (CA)
Inventor: FRADERA PELLICER CARLOS
IPC: E04C2/06
Filed: 2007-12-03
Abstract: This cement mortar panel with pretensed biaxial reinforcement, comprises a cement mortar plate that, is between 2 and 7 cm. thick and includes a biax ial reinforcement, with hidden in the cement mortar means for versatile oper ation of the whole panel enabling handling and/or fastening thereof to a bui lding structure, said means of versatile operation comprise, firstly means o f retention in the hardening cement mortar and secondly and conversely, mean s for any type of securing for manipulation elements for the panel and means for fastening the same to the building structure.
Patent CA-2691618-A1 (CA)
Inventor: BIGLER MICHAEL E
IPC: A61P19/08
Filed: 2008-06-24
Abstract: The invention provides methods for treating bone resorption disorders with antagonists of MDL-1.
Patent CA-2694171-A1 (CA)
Inventor: WIEMERS REGINALD A
IPC: C02F9/06
Filed: 2008-07-31
Abstract: An electrocoagulation apparatus is disclosed integrated with a plate clarifier for effluent treatment. The clarifier includes first and second tanks, an electrocoagulation reactor positioned in the first tank.
Patent CA-2694661-A1 (CA)
Inventor: BAUER JOERG
IPC: C12N15/82
Filed: 2008-07-30
Abstract: The invention relates to polynucleotides from Helobdella robusta, Laccaria bicolor, Lottia gigantea, Microcoleus chthonoplastes, Monosiga brevicollis, Mycosphaerella fijiensis, Mycospaerella graminicola, Naegleria gruben, Nectria haematococca, Nematostella vectensis, Phycomyces blakesleeanus, Trichoderma resii, Physcomitrella patens, Postia placenta, Selaginella moellendorffii and Microdochium nivale that code desaturases and that can be used for the recombinant production of polyunsaturated fatty acids. The invention also relates to the vectors, host cells and transgenic non-human organisms that contain said inventive polynucleotides, and also the polypeptides coded by said polynucleotides. The invention further relates to antibodies against the inventive polypeptides. Finally, the invention relates to production methods for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to the use thereof as medicments, cosmetics, food, animal food, preferably fish food or food supplements.
Patent CA-2695498-A1 (CA)
Inventor: MURAYAMA SHIGEHARU
IPC: G01M3/26
Filed: 2008-07-31
Abstract: It is an object to provide an electro-acoustic converter which can be subjected to air leakage test allowing a gas to pass through a waterproof film in such a condition that the waterproof film is attached to the electro-acoustic converter.  An electro-acoustic converter is produced, which includes: a casing having a sound hole; and a diaphragm provided in the casing, wherein the sound hole is covered with the waterproof film to form a closed space, and the closed space is in communication with the outside of the casing through a vent for air leakage test.
Patent CA-2695519-A1 (CA)
Inventor: ADHAM NIKA
IPC: A61K31/4965
Filed: 2008-08-04
Abstract: The present invention relates to pharmaceutical compositions containing dopamine receptor ligands and selective serotonin reuptake inhibitors and to methods of treating disorders such as schizophrenia, major depressive disorder and bipolar de-pression using combinations of dopamine receptor ligands and selective serotonin reuptake inhibitors. The present invention also relates to methods of treating depression using dopamine receptor ligands.
Patent CA-2696536-A1 (CA)
Inventor: HALL TIMOTHY
IPC: G08G1/087
Filed: 2010-03-15
Abstract: Various approaches for activating a traffic control preemption system. A light bar includes a support structure and a plurality of LED modules individually mounted on the support structure. Each LED module includes a plurality of LED groups, and in at least one of the plurality of LED modules, at least one LED group in the module is an infrared (IR) LED group, and at least one LED group in the module is a visible light LED group. A controller is coupled to each module. The controller is configured to trigger an IR light pulse pattern at a first level of IR radiant power from the at least one IR LED group. The pulse pattern and first level of IR radiant power activate preemption in a traffic control preemption system.
Patent CA-2697966-A1 (CA)
Title: Self-dispersed pigments and methods for making and using the same
Inventor: SHING VINCENT
IPC: C09C3/08
Filed: 2008-08-22
Abstract: A method of modifying a pigment that includes reacting a reactive compound having an X-[Y]a reactive group with a secondary compound N-S-ZM to form a substituted reactive intermediate [Y]a-X-(N-S-ZM)b. A pigment is reacted with the substituted reactive intermediate [Y]a-X-(N-S- ZM)b to attach the substituted reactive intermediate to the surface of the pigment to form a surface modified pigment. X may be a sulfonyl, phosphoryl, or 1,3,5-triazinyl group, Y may be a halogen leaving group, N  may be a basic nucleophilic group, S may be an organic group, and ZM may be an ionizable end group. Also, n is an integer between 1 and 3, b is an integer between 1 and 3, and a = n-b. When n is equal to or greater than b, and if b is 2 or 3, each N-S- ZM can be the same or different.
Patent CA-2699094-A1 (CA)
Inventor: LEVIT NATALIA V
IPC: G01K11/16
Filed: 2008-10-31
Abstract: A passive distributed vibration absorber that utilizes multiple discrete mass elements (3) and a viscoelastic layer (2) and that effectively attenuates vibration in modally dense structures(1) excited by a broadband input noise excitation and is tunable to multiple natural frequencies in such modally dense vibrating structures including low frequencies.
Patent CA-2703759-A1 (CA)
Inventor: DRAKULICH DAN
IPC: F27D1/16
Filed: 2008-10-29
Abstract: A method of repairing a refractory brick wall in a furnace that includes: (a) identifying a refractory brick wall or portion thereof that requires repair/reconstruction, pre engineering construction dimensions and accommodating various battery oven designs and oven heating systems; (b) demolishing the refractory brick wall or wall portion thereof identified in step (a); (c) installing outer reusable forms in situ, defining a new wall or portion thereof; (d) installing inner consumable forms defining one or more passageways within the new wall or portion thereof; and (e) pouring castable material into one or more areas bounded by the outer forms; (f) curing said castable material; and (g) removing the outer reuseable forms.
Patent CA-2703894-A1 (CA)
Inventor: MATTSBY-BALTZER INGER
IPC: C07K14/79
Filed: 2008-11-10
Abstract: The present invention relates to new arginine substituted peptides designed based on the sequence of human lactoferrin and to use thereof, in particular for treatment and/or prevention of infections, inflammations, tumours, pain, wounds and/or scars.
Patent CA-2704516-A1 (CA)
Inventor: PEABODY JOSHUA TODD
IPC: H02J17/00
Filed: 2010-05-17
Abstract: A system for providing wire-free and contact free electric power and communication connection in a security installation between a door and a frame. The cores, windings, and control circuits of first and second portions of a split core transformer are disposed in the frame and the door, respectively. Power applied to the first portion induces a voltage and current in the second portion when the door is in a closed position. Modulation of the voltage amplitude in either the first or second portion defines a communication signal between the door and the frame. Status and data are transmitted at data rates that are essentially twice the frequency of the voltage applied to the split core transformer. In a second embodiment, voltage transfer occurs at 20 KHz and data transfer is in the range of 100K baud.
Patent CA-2704567-A1 (CA)
Inventor: IWANAGA EMA
IPC: A61M1/02
Filed: 2008-12-26
Abstract: This object aims to provide a fiber construct which is made up of ultrafine fibers and yet can stably sustain voids among fibers even in the case of being packed into a small-sized column. Namely, a fiber construct for treating biological components which is made up of fibers having an average diameter of less than 50 µm and in which a part of the above-described fibers are curled.
Patent CA-2705166-A1 (CA)
Inventor: HAVERTY DONNCHA
IPC: A61L27/12
Filed: 2008-11-12
Abstract: The present application is directed to methods of manufacturing calcium phosphate particles.  In particular, the method is directed at eliminating the requirement for a sintering step in the manufacturing process. The method involves the atomisation and combustion of one or more antecedent compositions containing calcium precursors, phosphorus precursors and hydrogen peroxide.
Patent CA-2705262-A1 (CA)
Inventor: ALI AMJAD
IPC: A61K31/41
Filed: 2008-11-21
Abstract: A compound having the structure (A) wherein R is an angiotensin receptor antagonist active group, and Y is 1)2 -(CH2)3R5, 2) -C(O)(CH2)2R5, 3) -C(R1R2)OC(O)O(CH2)n R5, wherein n is 1 or 2, 4) -C(R1R5)OC(O)CH2CH2R5, 5) -C(R1R2)OC(O)OCH2CH2C(R3R4)R3, Formula (B), and Formula (C) provided that when Y is -C(O)(CH2)2R5, then R is Formula (D) R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-4 alkyl; R5 is CH(ONO2)CH(ONO2)R6;  R6 is selected from CH3, CH2CH3 and CH(CH3)2; or a pharmaceutically acceptable salt or hydrate thereof, which is useful for treating hypertension.
Patent CA-2707105-A1 (CA)
Inventor: ERICKSON SHAWN DAVID
IPC: A61P3/04
Filed: 2008-12-02
Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as obesity.
Patent CA-2707343-A1 (CA)
Inventor: BOSTERLING WINFRIED
IPC: E01B9/38
Filed: 2009-01-08
Abstract: The invention relates to a support for a system 1 for fastening a rail 2 on a substrate 3, comprising an angle bracket 14, which has a base section 23 with a contact surface 23a associated with the respective substrate 3, also comprising a supporting section 22, standing on the base section 23, which on its free front side associated with the rail 2 to be fastened has a bearing surface 21, and also having a through hole 29 formed in the base section 23 for inserting a fastening element 17, 19 intended for fixing the angle bracket 14 on the substrate 3. With such a support reliable support of the rail in service, also with greater tolerance for positioning the individual components, according to the invention is ensured by the fact that the through hole 29 at least in a direction aligned parallel to the contact surface has an over-measure in relation to the circumference of the part 19, in the assembled condition sitting in the through hole, of the fastening element 17, 18 and by the fact that an additional locking piece 15, 16, cooperating with the fastening element 17, 18 for fixing the angle bracket 14 in a particular relative position obtained by a relative movement of fastening element 17, 18 and angle bracket 14, is also provided.
Patent CA-2707521-A1 (CA)
Inventor: MACLEOD ANGUS
IPC: C07D487/04
Filed: 2008-08-20
Abstract: Novel imidazopyrazine compounds are disclosed that have a formula represented by the following: Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a viral infection, in particular a HCV, HRV, Sb and/or CVB in a patient in need thereof.
Patent CA-2708512-A1 (CA)
Inventor: BARONI SERGIO
IPC: A61P1/00
Filed: 2008-12-23
Abstract: In one aspect, the present invention relates to amino-salicylic -aminophenylpropionic compounds for the use in the treatment of the inflammatory component of the celiac disease. These compounds act by blocking the cytokines released in the celiac disease and are specifically useful in the treatment of cases refractory to the diet, in dietary errors and in the reduction of the celiac disease remission time.
Patent CA-2708911-A1 (CA)
Title: Systeme de determination d'un modele de commercialisation
Inventor: GUILD JOHN A
IPC: G06Q30/00
Filed: 2010-07-05
Abstract: Un système comprend un module de détermination de la variable qui détermine une variable opérationnelle pour être utilisée pour le modèle final et qui détermine également une modification à la au moins une variable. Un module de détermination hypothétique détermine un élément opérationnel hypothétique à être utilisé pour le modèle final. Lhypothèse comprend une transformation pour la variable qui décrit comment la variable présente un impact sur lobjectif de commercialisation ou la manière dont la variable présente un impact sur une autre variable opérationnelle à être utilisée dans le modèle final. Le module hypothétique détermine également une modification de lhypothèse. Un générateur de modèle génère un modèle candidat qui utilise la variable et lhypothèse et génère un nouveau modèle candidat qui utilise lhypothèse modifiée, la nouvelle variable ou la modification de la variable. Le modèle candidat ou le nouveau modèle candidat est opérationnel pour être sélectionné comme modèle final basé sur la au moins une mesure statistique et une indication de pertinence pour la variable dans le modèle candidat et le nouveau modèle candidat.
Patent CA-2709799-A1 (CA)
Inventor: KORWIN-EDSON MICHELLE L
IPC: C08J9/00
Filed: 2007-12-28
Abstract: Foams for filling cavities and crevasses and for forming foamed products are provided. The latex foam may include an A-side containing a functionalized latex and a B-side that contains a crosslinking agent and optionally a non-functionalized latex.  The A- and/or B-side contain a blowing agent package or components forming the blowing agent package. The blowing agent package may be the combination of two or more chemicals that when mixed together form a gas or a chemical compound that, when activated by heat or light, forms a gas. In an alternate embodiment, the latex foam includes a functionalized latex, an acid, and an encapsulated crosslinking agent and base. Alternatively, the spray latex foam may include a functionalized latex, a crosslinking agent, and an encapsulated dry acid and dry base. The encapsulating agent may be a protective, non-reactive shell that can be broken or melted at the time of application
Patent CA-2710650-A1 (CA)
Inventor: KOHLI RAJNISH
IPC: A61K8/24
Filed: 2008-03-28
Abstract: This invention relates to oral care compositions comprising an effective amount of a salt of a basic amino acid, the salt having a pH in an unbuffered solution of less than about 7.5: an effective amount of a soluble fluoride salt: and a particulate material which has a pH in an unbuffered solution of less than about 7.5; and to methods of using and of making such compositions.
Patent CA-2710796-A1 (CA)
Inventor: MUEH EKKEHARD
IPC: C01B33/107
Filed: 2008-11-20
Abstract: The invention relates to a method for reducing the content in elements of the third main group of the periodic system, especially in boron- and aluminum-containing compounds of technically pure halosilanes for producing high-purity halosilanes, especially high-purity chlorosilanes. The invention further relates to an installation for carrying out said method.
Patent CA-2712345-A1 (CA)
Inventor: PATEL NIMESHKUMAR KANTILAL
IPC: C10G33/04
Filed: 2008-12-17
Abstract: A method for breaking a crude oil emulsion includes treating the emulsion at an elevated temperature with a demulsifier.  The demulsifier contains at least 70 percent by weight of ethylene oxide, 3-hydroxypropylene oxide, or a mixture and has a cloud point temperature of at least about 100°C. A method for desalting the crude oil is also provided.
Patent CA-2712777-A1 (CA)
Inventor: BENKO ZOLTAN
IPC: C07D239/47
Filed: 2009-01-22
Abstract: This present disclosure is related to the field of 5-fluoro pyrmidines and their derivatives and to the use of these compounds as fungicides.
Patent CA-2713747-A1 (CA)
Inventor: VAN DEURSEN GARY E
IPC: A47L13/08
Filed: 2009-01-30
Abstract: A scraper is provided with a first member having an upper housing and a lower jaw, a second member having a lower housing and an upper jaw, and a slide latch for clamping the upper housing to the lower housing. The first and second members are pivotally connected to each other such that when the upper and lower housings are clamped together by the latch, the upper and lower jaws are clamped together to hold a blade between them. The slide latch engages an end portion of the upper and lower housings in order to clamp the jaws together. The slide latch has ridges to assist a user to push the slide latch forward to lock a blade into place and backward to release a blade. The lower housing has a cavity for storing spare blades.
Patent CA-2716114-A1 (CA)
Inventor: BRAINERD JEFFREY
IPC: G06F17/30
Filed: 2009-02-26
Abstract: Presenting a diagram includes: receiving a request that identifies a first data item stored in a data management system from a user interface; retrieving stored configuration information that includes a plurality of selection specifications for selecting data items in the data management system that are related to a given data item of a predetermined type; querying the data management system to identify a set of one or more data items according to a selection specification that is associated with a type of the first data item; for each of multiple returned data items in the identified set, querying the data management system to determine whether additional data items are identified according to a selection specification that is associated with a type of the returned data item; generating a diagram indicating relationships among data items identified using the configuration information; and presenting the generated diagram over the user interface.
Patent CA-2718520-A1 (CA)
Title: Identification of micro-rnas involved in neuromuscular synapse maintenance and regeneration
Inventor: WILLIAMS ANDREW
IPC: A61K48/00
Filed: 2009-03-17
Abstract: The present invention relates to the identification of miRNAs that are involved in the process of neuromuscular synaptic maintenance and regeneration following injury or disease. Modulation of these miRNAs is proposed as treatment for spinal cord injury and neurodegenerative disease.
Patent CA-2719861-A1 (CA)
Inventor: GRUBER MARKUS
IPC: F16D55/00
Filed: 2009-04-02
Abstract: The invention relates to an arrangement of a bellows on a guide mandrel of a disc brake, particularly of a commercial vehicle, wherein an end of the bellows comprising a sealing ring, particularly a quadring lies in a circumferential groove of the guide mandrel, and is thereby pressed into the groove by a retaining ring placed thereon, designed so that an air passage can form in the contact area of the sealing ring at the base of the groove, reducing the volume enclosed by the bellows and the guide mandrel. To this end, the contact shoulder formed on the retaining ring is circumferentially interrupted in segments.
Patent CA-2722002-A1 (CA)
Inventor: SIM SYLVIE
IPC: A61K9/20
Filed: 2009-04-29
Abstract: Lacrimal implants, methods of making lacrimal implants, and methods of treating ocular, respiration or other diseases or disorders using lacrimal implants are disclosed.
Patent CA-2722290-A1 (CA)
Title: Scratch card game system and corresponding game platform
Inventor: PORTEAUX ETIENNE
IPC: A63F3/06
Filed: 2010-11-19
Abstract: The game system is characterized in that it comprises a first instant game based on the purchase by a player of a game medium (1) that, in particular, bears results information for said first instant game, accessible to the player after removing a first mask and that reveals itself to be either winning (1b, 1c) or losing (1a), the winning result information in the first instant game indicating to the player either direct winnings (1b) on said first instant game, or a right (1c) to participate in a second instant lottery game accessible via an instant and automatic lottery computer server means. (See Formula I)
Patent CA-2722845-A1 (CA)
Inventor: SEOL HYUN UK
IPC: A61K31/55
Filed: 2009-05-19
Abstract: The present invention provides an oral pharmaceutical composition for the treatment of premature ejaculation, and the composition provides the effective and excellent treatment of premature ejaculation as well as reduced side effects like nausea, vomiting, drowsiness, sedation effect, awakening effect, and weight-loss etc.
Patent CA-2723069-A1 (CA)
Inventor: BRATHWAITE NICHOLAS E
IPC: G06Q50/00
Filed: 2003-02-21
Abstract: Designing an electronic component (1200) includes receiving a device criteria (e.g., a parametric value, procurement value, etc.) from a designer (1202), querying a database for devices corresponding to the device criteria (1204), querying the database for procurement data and/or engineering data associated with the corresponding devices (1206), presenting the devices to the designer based on the procurement data (1208), and receiving input from the designer identifying one of the presented devices as a selected device (1210).
Patent CA-2723620-A1 (CA)
Inventor: JIANG NAN
IPC: B82B3/00
Filed: 2009-05-15
Abstract: A photo-curing or photosintering process is utilized to modify, reduce or eliminate whiskers or nanowires growing on a material surface.