baber/WOPTO huggingface dataset:
Patent MA-21601-A1 (MA)
IPC: A61P31/12
Filed: 1989-07-21
Abstract: A process for the preparation of a compound of formula (I) or a pharmaceutically acceptable salt thereof: <CHEM>  which process comprises reacting a compound of formula (I): <CHEM> wherein the amino group is optionally protected, Y is iodo, optionally substituted benzylthio or (phenacylmethyl)thio, with a compound of formula (III): <CHEM> wherein Q is a leaving group, Rx and Ry are protected hydroxymethyl or acyloxymethyl, or group(s) convertible to hydroxymethyl or acyloxymethyl; and Rz is hydrogen or a group convertible thereto; and thereafter converting Y to X is hydroxy by means of hydrolysis, or to X is hydrogen by means of reduction; converting Rx and Ry when other than hydroxymethyl or acyloxymethyl, to hydroxymethyl or acyloxymethyl, optionally converting Rx/Ry hydroxymethyl to acyloxymethyl or vice versa, deprotecting the 2-amino group where necessary and converting Rz, (when other than hydrogen) to hydrogen; and optionally forming a pharmaceutically acceptable salt thereof.
Patent MA-25878-A1 (MA)
Inventor: GRIMAL JEAN-MICHEL
IPC: D21H21/40
Filed: 2002-06-06
Abstract: The invention concerns a security document comprising a support consisting of a sheet of paper with fibrous texture, characterised in that the fibrous texture is impregnated over its entire thickness with a protective substance, such that said substance provides a coating for the fibres of the texture and covers the binding zones of said fibres, the pores of said support being hermetically closed by the coating.
Patent UY-27863-A1 (UY)
Title: Nueva combinacion
Inventor: FOX DAVID NATHAN ABRAHAM
IPC: A61P43/00
Filed: 2003-06-24
Abstract: Combinaciones que comprenden a) un inhibidor de fosfodiesterasa de tipo 5 (PDE5) específica de monofosfato de guanosina cíclico (CMPC) y b) un antagonista del receptor de angiotensina II, útiles en el tratamiento de la hipertensión.
Patent UY-29323-A1 (UY)
Title: Uso de colorantes de cianina para el dignostico de enfermedades proliferativas
Inventor: SCHIRNER MICHAEL
IPC: C07D209/10
Filed: 2006-01-02
Abstract: Uso del colorante de cianina SF64 para el diagnóstico de enfermedades proliferativas con una administración que comprende menos que 5 mg/kg de peso corporal
Patent UY-29712-A1 (UY)
Title: Sal de derivado de piperidina, composición farmacéutica que la contiene y aplicaciones
Inventor: JOSEFSSON BO-GORAN
IPC: C07D211/58
Filed: 2006-07-31
Abstract: La invención proporciona furoato de N-(2-(((2S)-3-((1-(4-clorobencil)piperidin-4-il)amino)-2-hidorxi-2-metilpropil)oxi)-4-hidroxifenil)acetamida o un solvato del mismo, composición farmacéuticas que contienen dicha sal o solvato y el uso de la sal o solvato en terapia.
Patent UY-31192-A1 (UY)
Title: Un nuevo procedimiento para preparar ácido 2-(3-{6-[2,4-diclorofenil)-etilamino]-2-metoxipirimidin-4-il}-fenil)-2-metil-propiónico
Inventor: ELIZABETH SECORD
IPC: A61K31/505
Filed: 2008-06-27
Abstract: Esta invención se refiere a un procedimiento para preparar ácido 2-(3-{6-[2-(,4-dicloro-fenil)-etilamino]-2-metoxi.pirimidin-4-il}-fenil)-2-metil-propiónico.
Patent UY-31577-A1 (UY)
Title: Proceso para la preparacion de 6-sustituido-1-(2h)-isoquinolinonas
Inventor: HERMUT DR WEHLAN
IPC: A61K31/4725
Filed: 2008-12-23
Abstract: La presente invencion se refiere a un proceso para preparar derivados de 6-sustituido-1-(2H)-isoquinolinona de formula (I) en el que R1 y n son como se describe en la memoria descriptiva. La presente invencion se refiere además a nuevos intermedios que se usan en el proceso de acuerdo con la invencion y a procesos para tales intermedios.
Patent ZW-17888-A1 (ZW)
Title: Improvements in or relating to avian control
Inventor: PETER WILLIAM GREIG-SMITH
IPC: A01N37/14
Filed: 1988-12-14
Abstract: Compounds of formula (I) <CHEM> wherein X<1> and X<5> are each separately selected from hydrogen and C1-4 alkyl, halogeno and halogeno-substituted C1-4 alkyl groups; X<2>, X<3> and X<4> are each separately selected from hydrogen and C1-4 alkyl, hydroxy, C1-4 alkoxy and phenoxy groups; R<1> and R<2> are each separately selected from hydrogen and C1-4 alkyl groups; R<3> and R<4> are each hydrogen or together constitute the second bond of a carbon-carbon double bond joining -CR<1>R<3>- and -CR<2>R<4>-; and Y is hydroxymethyl, formyl, cyano, carbamoyl,carbamoyl N-substituted by one or two of the same or different C1-4 alkyl groups, carboxy or a carboxylic ester or carboxylate salt, are of value as avian repellents.
Patent ES-174567-A1 (ES)
Title: Un procedimiento de purificar glicerina que contiene impurezas ionizables.
Filed: 1946-08-08
Abstract: Un procedimiento de purificar glicerina que contiene impurezas ionizables caracterizado por hacer pasar la glicerina impura por un sistema que contiene pluralidad de pares de cambiadores de iones siendo el primer miembro de cada par un cambiador de zeolita e hidrógeno y siendo el segundo miembro un cambiador de aniones.
Patent ES-182135-A1 (ES)
Title: Mejoras en acoplamientos de antena
IPC: H04B1/58
Filed: 1948-02-06
Abstract: Mejoras en acoplamientos de antenas, constituídas por una combinación de transmisor, receptor, una antena común para dicho transmisor y receptor, una primera línea de transmisión que conduce desde dicho transmisor a dicha antena, una segunda línea de transmisión que proviene de dicho receptor, un transformador conectado entre dicha segunda línea de transmisión, incluyendo dicho transformador dispositivos para elevar la tensión desde dicha primera línea de transmisión a dicho transformador y dispositivos para reducir igualmente la tensión desde dicho transformador a dicha segunda línea de transmisión, un dispositivo de descarga de espacio conectado a través de dicho puente de transmisión e intermedio entre dichos dos dispositivos elevadores y reductores, teniendo dicho dispositivo de descarga una tensión de ruptura característica que es un pequeño porcentaje de la tensión aplicada a dicho transformador desde dicha primera línea de transmisión, por lo cual la tensión resultante que se aplicaa dicha segunda línea de transmisión a través de dicho segundo dispositivo es un pequeño tanto por ciento de la tensión de ruptura.
Patent ES-182804-A1 (ES)
Title: UN SISTEMA DE ESCAPARATES MoVILES
Filed: 1948-02-21
Abstract: Un sistema de escaparates móviles caracterizado por el hecho de formar el plano de apoyo del escaparte con una plataforma móvil capaz de girar sobre si misma de desplazarse del ámbito del escaparate con movimiento planetario o de forma con otras semejantes una cadena o tren que saliendo del ámbito del escaparate se introduzca en la parte interior de la tienda para dar lugar a cambiar modificar o sustituir el contenido en mercancía expuesta sobre cada plano o unidad a cada vuelta completa de la cadena.
Patent ES-183825-A1 (ES)
Title: Un motor a tiempo variable, de fuerza propia y movimiento constante, accionado por ilimitadas palancas, bielas, sectores dentados y cremalleras
Filed: 1948-05-25
Abstract: Motor a tiempos variables, accionado potencialmente por un sistema de palancas cruzadas, de segundo género, cuyos puntos generales de aplicación soportan tirantes verticales que se unen a los puntos intermedios, de esfuerzos de un par de palanquitas de tercer género, las que actuan sobre un sistema transformador de potencia, que se pone en movimiento merced a desequilibrio potencial de las palanquitas (brazos desiguales). Ese transformador recibe la potencia indicada por su origen o primer engranaje, que se transmite a los sucesivos elementos, que son sectores circulares dentados con sus correspondientes cremalleras verticales, cuyos elementos van respectivamente aumentando en radio y longitud de recorrido, y con intermedio de sectores amplificadores de potencia, se llega a la cremallera final, con potencia multiplicada y mayor espacio de recorrido, la cual lleva un eje horizontal en que se aloja la biela motriz la que conecta con el árbol general del motor, al que imprime fuerza y movimiento. Durante cuya marcha (primera semirrevolución al eje, o acción potencial) en cada tiempo un sistema especial elevador de pesos (que engrana por su extremidad inferior con el árbol general) y por su superior con el sistema de palancas por el intermedio de la barra porta-pesos, se halla deformado y por ello inactivo, dejando que los pesos actuen sobre el sistema de palancas, para su desarrollo potencial actuante sobre el transformador. El elevador actúa elevando los pesos precisamente por sus bases, ya mantenido en su posición rígida, actuante, cuando la acción potencial ha terminado, entonces (en la segunda semirrevolución al eje) los sistemas de palancas y transformador, quedan libres para que deshaciendo sus anteriores movimientos vuelvan al punto de partida, y así sucesivamente repitiéndose lo explicado, se produce el movimiento constante.
Patent ES-187365-A1 (ES)
Title: PERFECCIONAMIENTOS INTRODUCIDOS EN LAS LáMPARAS DOMÉSTICAS DE ALUMBRADO
Filed: 1949-03-08
Abstract: Perfeccionamientos introducidos en las lámparas domésticas de alumbrado caracterizados porque sobre el depósito de combustible va montada una llave en forma de cruz que conecta por la parte inferior con un tubo que está en contacto contínuo con el combustible líquido del depósito y por la parte superior va unido al mecanismo central del aparato.
Patent ES-190352-A1 (ES)
Title: Método para preparar materiales semiconductores, especialmente de germanio, para traslatores eléctricos
Filed: 1949-11-05
Abstract: Método para preparar materiales semiconductores especialmente de germanio para traslatores eléctricos y comunicar a estos materiales una resistividad y un tipo de conductividad previstos caracterizado porque se calienta un material de germanio que contenga impurezas aditivas y sustractivas a una temperatura comprendida entre unos 400º y 900º C. y luego se enfría a la temperatura normal.
Patent ES-199395-A1 (ES)
Title: UNA BáSCULA DIVISORA ELECTROAUTOMáTICA ADAPTABLE A LOS PROCESOS DE FABRICACIoN CONTINUA, ESPECIALMENTE EN LA DEL PAN
Filed: 1951-08-22
Abstract: Báscula divisora electroautomática adaptable a los procesos de fabricación contínua especialmente en la del pan que se caracteriza por constar de una tolva para la alimentación contínua de la masa pastosa a controlar sobre su plato de carga; de un conjunto de mecanismos propios para efectuar la medición del peso depositado sobre el plato; porque su plato de carga. es basculante alrededor de un eje horizontal porque este plato queda enlazado axialmente con un mecanismo de giro satélite del mecanismo que asegura la expulsión contínua de la pasta contenida en la tolva; por la condición intermitente del mecanismo de giro regulado por un dispositivo de embrague electromagnético dispuesto entre tal mecanismo y el eje de propulsión general de la máquina porque esta intermitencia de funcionamiento es función precisamente del peso depositado en la plataforma de carga; y por constar esta báscula de una cinta de transporte inferior que recoge la materia pastosa ya pesada y racionada.
Patent ES-250199-A1 (ES)
Title: New halogeno-androstenes
IPC: C07J1/00
Filed: 1959-06-17
Abstract: The invention comprises D 4-9a -chloro- and -fluoro - 17a - methyl-3b :11b :17b -trihydroxyandrostenes and 3-esters thereof. They are prepared by reduction with a complex lightmetal hydride of the corresponding 3-ones with subsequent esterification if desired. Esters of saturated and unsaturated aliphatic, cycloaliphatic, aromatic and heterocyclic carboxylic acids, including amino-acids and halogencontaining acids, of sulphonic, phosphoric and sulphuric acids, and semi-esters of dicarboxylic acids in which the free carboxyl group may also be esterified, or salified with alkali metals or organic bases, are described. The androstenes of the invention, which are stated to be highly androgenic, may be made up with suitable carriers into pharmaceutical preparations. These may take the form of oily or aqueous solutions, ampoules, suspensions, emulsions, implants, tablets, dragees, ointments or creams, and may contain preservatives, stabilizers, wetting agents, salts for varying the osmotic pressure or buffers.
Patent ES-259726-A1 (ES)
Title: Process for vulcanizing pre-shaped articles formed from vulcanizable polymeric materials
IPC: B29C48/09
Filed: 1960-07-16
Abstract: Fabrics are coated by roll-milling on to a textile support a mix comprising an amorphous elastomeric ethylene-propylene copolymer, immersing the coated support in a bath containing organic peroxide solution and curing it. The mix which may also be extruded to form pipes, cables, insulating sheaths &c. may include carbon black and sulphur, be coated on to a cotton cloth and then immersed in an acetone bath at 40 DEG C. containing tetra-chloro tert butyl peroxide removed and dried and finally cured at 150 DEG C. for 30 minutes. Amorphous copolymers of ethylene and a -olefins are described in Specifications 856,733, 856,736 and 856,737.
Patent ES-289045-A1 (ES)
Title: Substituted 2-hydroxy-benzo[a]quinolizines and a process for the manufacture thereof
Filed: 1963-06-14
Abstract: The invention comprises compounds of the beta series of the general formula <FORM:0999404/C2/1> wherein the broken lines denote bonds leading to optional groups, R1 and R2 each signify an alkoxy group or together signify an alkylenedioxy group, R3 signifies an alkyl or alkenyl group and R4 signifies an alkyl, alkenyl, aralkyl, aryl, dialkylaminoalkyl or a piperidinoalkyl group and their esters and ethers and acid addition salts of said compounds, ethers and esters and the preparation thereof by reacting a 2-oxobenzo [a]quinolizine with a Grignard compound of the general formula R4-Mg-Halogen, hydrolysing the condensation product and, if desired, converting the resulting tertiary carbinol into an acid addition salt or, alternatively, if desired, esterifying or etherifying said carbinol, and, if desired, converting the resulting ester or ether into an acid addition salt. Racemic mixtures of compounds may be resolved into their optical isomers. Pharmaceutical compositions having sedative and narcosis-potentiating action comprise the compounds of the invention and a pharmaceutical carrier. The compositions, which may also contain other therapeutically active substances, may be formulated as tablets, dragees, suppositories, capsules, solutions, suspensions or emulsions. Specification 789,789 is referred to.
Patent ES-293250-A1 (ES)
Title: Lubricated rubber bearing
IPC: F16C33/22
Filed: 1963-11-06
Abstract: A bearing has a relatively hard porous member consisting of a closely packed mass of randomly distributed fibres which are coated with polymer so that the fibres adhere to one another and provide pores between them containing lubricant, the porous member having a back face which is connected to a relatively soft elastomeric supporting member and a front face slidably engaging a member which is harder than the porous member. In an embodiment, a bushing 10, Figs. 1 and 2 (not shown), comprises a porous member 11, which has fibres such as paper coated with latex for example, and an elastomeric supporting member 13 attached to the bushing 10. The member 11 has lubricant in the pores thereof, the lubricant being silicone grease or graphite, for example. End-flanges 17, 18 of the bushing 10 provide sealing means between the latter and a tubular member 15. The elastomeric member 13 is preferably backed by a tubular member 19 which facilitates assembly and lubricant-retaining reservoirs 16 may be provided. In assembling the bearing, latex-impregnated compressed paper is placed in a mould and the elastomeric member 13 is partially cured so as to provide good adhesion. The sub-assembly is then placed in the tubular member 15 and finish-curing is effected so as to provide a permanent set. The bearing may be used for a pivotal joint as used on motor vehicles, Fig. 3 (not shown), ball joints, Fig. 4 (not shown), clutch-faces and thrust washers, Figs. 5 and 6 (not shown), for example.
Patent ES-298676-A1 (ES)
Title: Redox catalytic oxidation of olefins to aldehydes and ketones
IPC: B01J31/40
Filed: 1964-04-14
Abstract: Aldehydes or ketones are prepared by contacting an olefinic compound in an essentially halide free system in the presence of water and a polar organic solvent with a reducible transition metal catalyst present as a co-ordinate complex with a non-olefinic neutral ligand or salt of a weak acid a co-oxidant which is a compound of a metal having at least two oxidized states, the higher of which is capable of oxidizing the reduced form of the transition metal compound, and the lower of which is capable of being oxidized to the higher by O2 or an O2 producing oxidant and a titratable base. The olefinic compound may be an alkene, alkadiene, cycloalkene, vinylcycloalkane or alkenybenzene. The catalyst and co-oxidant may be co-ordinate complexes of metals and non-olefinic compounds, e.g. b -dicarbonyl ketones and esters of b -ketonitriles, or metal salts of weak acids, preferably alkanoic acids. The catalyst metal is preferably Pd but may also be Pt, Ir, Rh, Ru, Os or Au. The co-oxidant metal is preferably Cu but may be another transition metal of Groups Ib, VIb, VIIb or VIII, e.g. Fe, Cr, Co, Ni, Mo, W, Mn or Pb. The titratable base may be a basic salt or a carboxylic acid An oxidizing agent, e.g. O2, air, or a compound. capable of releasing oxygen in the reaction may be present. The reaction may be effected in the vapour phase or liquid phase over a fixed catalyst bed, or as a homogeneous liquid phase reaction, wherein the solvent used may be a saturated aliphatic monocarboxylic acid, a nitrile, a sulphoxide, a sulphone, an amide, a dialkyl or cyclic carbonates, an ether, a diketone and esters. The examples refer to the preparation of acetaldehyde from ethylene, cyclohexanone from cyclohexene, and acetone from propylene.ALSO:A reducible transition metal catalyst present as a co-ordinate complex with a non-olefinic neutral ligand or salt of a weak acid, and a co-oxidant which is a compound of a metal having at least two oxidion states. The catalyst metal is preferably Pd but may also be Pt, Ir, Rh, Ru, Os or Au. The co-oxidant is preferably Cu but may be another metal of Groups IB, VIB, VIIB or VIII e.g. Fe, Cr, Co, Ni, Mo, W, Mn or Pb.
Patent ES-310806-A1 (ES)
Title: Weft-inserting devices for continuousfeed looms
IPC: D03J5/00
Filed: 1965-03-11
Abstract: The hooked spring clamp 2 which co-operates with a rigid member 1 to form a weft inserter is flexible at only one portion 2b situated between its rigid end 2d and seating 2c.
Patent ES-315812-A1 (ES)
Title: Improvements relating to joint covering strips
IPC: E04F19/06
Filed: 1965-07-26
Abstract: An extruded plastics joint cover strip 1 of T-section has a web portion 3 projecting into the joint 5 between, e.g. two partion panels 6 and 7, and secured therein by a number of spring clips 8 of generally U-shaped crosssection with at least one arm of the U having a tongue, e.g. 15, punched out of it. The strip 1 may have longitudinal serrations 4 on the web 3 for locating tongues 17, one of which extends inwardly from one arm of each clip of the type shown in Fig. 3. This clip has two tongues 15 on one arm, and a central, outwardly projecting tongue 11 on the other arm, with a central tongue 18 projecting in turn therefrom. Each of the outwardly projecting tongues has a curved end to grip the adjacent panels. In the embodiment of Fig. 4 (not shown), the web 23 extends in line with one finage 22 so that the strip may be used for a corner joint, and in the embodiment of Fig. 5, (not shown) the strip 33 has a smooth web, and the clips 37 each have a central, outwardly projecting, curved-ended tongues 44 or 45 on each arm, with curved-in end portions 40 or 41 to the surrounding arm portions, to grip the strip web.
Patent ES-342040-A1 (ES)
Title: Superplastic nickel alloys
IPC: C22C19/05
Filed: 1967-06-20
Abstract: A steel containing up to 0À08%C is characterized by a fine grained micro-structure comprising austenite or martensite in a ferrite matrix in which the transverse mean path between the austenite or martensite particles is so short (e.g. not above 8 microns) that when the steel is strained at 0À16-0À26 inch inch minute at 925-980 C. its tensile elongation is at least 150%. The steel may comprise Cr 18-35% Ni 2-12% C 0À08% max. Ti up to 1À5% # (a) up to 1À5% total V up to 1% # (b) Ti + V is at least Mn 0À1% 4 x (%C-0À03) Si 0-1% (c) For Cu 2% or more Mo 0-3% Mn does not exceed 0À3% Co 0-2% and Si does not exceed Cu 0-2À5% 0À4% (d) 1À17% (%Ni) + 13À3 # %Cr + %Mo # 3À5(%Ni) + 11 the balance, apart from up to 1% in total of Mg, Zr, Al, Ce, B and Hf and the lowest amounts possible of P, N, S, O and H, being iron. Steels as above containing 23-35% Cr and 4À5-12% Ni are said to be novel. The desired micro-structure is made by plastically deforming the steel (e. g. by 50%) in the two phase temperature region, the steel having a ferrite solid solution structure containing precipitable austenite, and heating the steel within the said region during or after the deformation to recrystallize the ferrite and precipitate the austenite. The alloys may be welded using a matching filler wire.
Patent ES-342181-A1 (ES)
Title: Rotary grinding mill
IPC: B02C17/04
Filed: 1967-07-22
Abstract: A ball or tube mill containing loose grinding bodies includes a built-in dam ring 3, Fig. 1, constituting a partition between a grinding chamber 1 and a discharge chamber 2 that has an outlet for the ground material. The discharge chamber has means to return the grinding bodies to the grinding chamber through the dam ring. The discharge chamber has lifters 7 for the grinding bodies adjacent the outlet side of the dam ring, and the grinding bodies in falling off these lifters tend to pass back through the opening 8 in the ring 3. The dam ring may be provided with openings, and scoops 11 to lift the ground material and discharge it into a hollow trunnion 5. In a further embodiment, the opening in the dam ring may be surrounded by a frusto-conical ring and the chamber 2 may have a frustoconical lining and a suspended plate which with a screw-thread in the trunnion further assists return of the grinding bodies to the mill. Other embodiments include a triangular section ring around the opening in the dam ring 3, and a plate carrying a frusto-conical protrusion a mill with three discharge compartments and a conveyor screw in the trunnion a mill with three compartments with dam rings 3', 22', 23', Fig. 7, whose central openings successively increase in diameter and a mill in which the last chamber has a lining so that there is a reduction in internal peripheral speed of the chamber and hence in the consequent tendency for grinding bodies to leave the chamber at its outlet. In a further embodiment two spiral rings 29, 30, Fig. 10, each have a mouth 31, Fig. 9, at the periphery of the discharge chamber 2. As the mill rotates some grinding bodies pass through the mouth 31 and move along the tube to its curved end 32 and are thus returned to the preceding grinding chamber. Ground material passes over a frusto-conical lining 14, through openings 9 in a dam ring 4, to be picked up by scoops and delivered into an outlet trunnion 5.
Patent ES-349638-A1 (ES)
Title: Neutron-Protection Material
IPC: G21F1/06
Filed: 1968-01-23
Abstract: A neutron absorbing shield is formed of boric anhydride with alumina and lime, or silica and lime, or magnesia and lime. The material may be used as a space-filling powder or an an aggregate in a concrete. When used as a protection against fast neutrons a neutron moderator is added, for example, a ground rock containing hydrogen. A vitreous form is prepared by fusing the mixture in a crucible and grinding the cooled mass. The materials used have a softening point above 500 C. and are thus suitable for fast reactors, their thermal expansion is compatible with hydraulic binders and they have a low solubility.