baber/WOPTO huggingface dataset:
Patent AU-2020391285-A1 (AU)
Title: Multifunctional multispecific multimeric biomolecule polymer having prolonged in-vivo duration
Inventor: PARK SUNGJIN
IPC: C12N9/10
Filed: 2020-11-27
Abstract: The present invention provides a multifunctional multispecific multimeric biomolecule polymer which is formed by obtaining a biomolecule, to which a ubiquitin C-terminal tag is bound, by recombinant-expressing the biomolecule from a host cell, and polyubiquitinating, in vitro, the biomolecule along with a substrate, and proteins E1 (activation enzyme), E2 (conjugation enzyme) and E3 (ligase) which are involved in ubiquitination, and thus having the biomolecule bind to a polyubiquitin scaffold which is formed by covalently bonding two or more ubiquitins. The biomolecule of the present invention may be one or more selected from the group consisting of a protein, peptide, polypeptide, antibody, antibody fragment, DNA and RNA, and, for example, by using heterologous proteins, modularized functionality may be imparted to the multifunctional multispecific biomolecule polymer. In addition, according to the present invention, the provided multifunctional multispecific multimeric biomolecule polymer is bound to a molecule capable of increasing in-vivo duration, and thus may be used for producing drugs requiring increased duration of efficacy in vivo. [Representative drawing] figure 30
Patent AU-2020428386-A1 (AU)
Title: Computer-implemented method for synchronizing a photoplethysmography (PPG) signal with an electrocardiogram (ECG) signal
Inventor: LAMBEIN XAVIER MARIE CHRISTIAN FERNAND
IPC: A61B5/024
Filed: 2020-11-19
Abstract: A computer-implemented method for synchronizing a PPG signal with an ECG signal comprises: - recording (101, 102) the ECG and PPG signals semi-synchronously; - cutting (103) the PPG signal into PPG signal pieces; - for a PPG signal piece (300): - determining (142-145) distances d between a vector of PPG peak times (301-315) and respective vectors of ECG peak times (351-365) for respective ECG signal pieces (350) obtained by applying different offsets o; - determining (104) a best matching ECG signal piece (350) with minimal distance do; and - registering (105) start time x of the PPG signal piece (300), start time yo of the best matching ECG signal piece (350), and the minimal distance do; - determining an offset and drift between the PPG signal and ECG signal as the offset and slope of a regression model (400) modelling the relation between the start time x and start time yo, inverse weighted by the minimal distance do; - applying the offset and drift to the PPG signal.
Patent AU-2021200343-A1 (AU)
Title: Alvocidib prodrugs having increased bioavailabilit
Inventor: SIDDIQUI-JAIN ADAM
IPC: A61P35/00
Filed: 2021-01-20
Abstract: Compounds having the following structure (1): or a stereoisomer, tautomer or pharmaceutically 
acceptable salt thereof, wherein one of R', R2 or R3 s -P(=O)(OH) 2, and the other two of R', R
2 and 
R3 are each H, are provided. Pharmaceutical compositions comprising the compounds, and methods 
for use of the compounds for treating diseases associated with overexpression of a cyclin-dependent 
kinase (CDK) are also provided.  
OR' O 
I I 
R20 0 
R3O 
Cl 
N
Patent AU-2021200595-A1 (AU)
Title: System and method for detecting tracking problems
Inventor: SHARMA MANISH
IPC: B60W40/114
Filed: 2021-01-29
Abstract: SYSTEM AND METHOD FOR DETECTING TRACKING PROBLEMS 
A tracking problem detection system (104) for a machine (102) may include 
tracking diagnostic circuitry (136) including one or more tracking diagnostic processors (406) 
configured to receive a location signal (134) indicative of a location of a machine (102) and a 
path signal (128) indicative of a path location (140) associated with at least a portion of a path 
(124) for the machine (102) to follow while maneuvering. The tracking diagnostic processors 
(406) may also be configured to determine a tracking difference (138) between the path location 
(140) and the location of the machine (102), and determine a frequency (704) of a signal 
associated with the tracking difference (138) and/or a frequency (704) of a signal associated with 
a yaw rate (410) associated with the maneuvering. The tracking diagnostic processors (406) may 
also be configured to detect, based at least in part on the frequencies (704) of the signals 
associated with the tracking difference (138) and/or the yaw rate (410), a tracking problem (144) 
associated with maneuvering the machine (102).
1/9 19-0810AU01 
TRACKINGPROBLEMDETECTIONSYSTEM 
104 
PATH TRACKINGDIAGNOSTICMODULE 
SIGNAL(S) 136 
128 OUTPUT 
- TRACKING TRACKING DEVICE 
LOCATION DIFFERENCE PROBLEM 146 
SIGNAL(S) 138 144 
CORRECTIVE 
ACTION 
148 
116 
110 
100 132 
112 
112 106 
126 12 
--- 108 
.. - - . 4- 122 
.---- - -124 
-- 0 
118 
120 
FIG. 1
Patent AU-2021201860-A1 (AU)
Title: Animal tag
Inventor: STEINFORT JOHN JAMES
IPC: A01K11/00
Filed: 2021-03-24
Abstract: : 
Tag apparatus (10) for attachment to the ear of an animal including a first portion (12) having a 
penetrating member (15) and a tail portion (16), the penetrating member (15) having a stem (18) 
5 and a head (13), the stem (18) forming a junction with the tail portion (16) at a proximal end (40) 
of the tail portion (16), said tail portion (16) further including a pair of sides (36, 38) and a distal 
end (34); a second portion (14) including a receiving member (22) adapted to receive and retain 
the head (13) of the penetrating member (15); wherein at the junction between the stem (18) and 
the tail portion (16) there is no overhanging material, such that upon the animal contacting a 
10 structure and pushing its head in through or away from the structure, there is no entanglement of 
the structure with the first portion (12) due to the structure moving the first portion (12) and 
either sliding against one side of the pair of sides (36, 38) or sliding over a top of the first portion 
(12).  
16
elf1 
*Fl-V-i, IA 
22.2 
.... .. ... ...... ... .. .... 7 
10~
Patent AU-2021202051-A1 (AU)
Title: Processor-implemented systems and methods for enhancing cognitive abilities by personalizing cognitive training regimens
Inventor: MARTUCCI WALTER EDWARD
IPC: G16H20/70
Filed: 2021-04-01
Abstract: Systems and methods are provided for the implementation of personalized cognitive 
training. As an example, a processor-implemented method is provided for enhancing 
cognitive abilities of a user by personalizing cognitive training regimens through difficulty 
progression. The method includes: performing a cognitive assessment of a user using a set of 
assessment tasks; estimating a maximal performance of the user related to the set of 
assessment tasks; determining a performance range based at least in part on the maximal 
performance of the user; dividing the performance range into a plurality of progress gates, the 
plurality of progress gates corresponding to a plurality of task difficulty levels; selecting a 
first progress gate within the performance range; generating a first set of training tasks 
associated with the first progress gate; and collecting the user's first training responses to the 
first set of training tasks.
Patent AU-2021203345-A1 (AU)
Title: Medical liquid administration device
Inventor: SAKAMOTO SHINGO
IPC: A61M5/168
Filed: 2021-05-24
Abstract: A medical liquid administration device is provided with a quick administration unit 
(110) for a medical liquid. The quick administration unit (110) has: an inflow passage 
(111); an outflow passage (112); a medical liquid storage unit (113) connected to 
between the inflow passage (111) and the outflow passage (112) and storing a 
medical liquid; and a control unit (114) for controlling both the storage of a medical 
liquid into the medical liquid storage unit (113) and the delivery of a medical liquid 
from the medical liquid storage unit (113). The inflow passage (111) has a first flow 
passage (111A) and a second flow passage (111B) which has a smaller flow 
passage cross-sectional area than the first flow passage (111A). The control unit 
(114) has: a first closure unit (141) for closing the first flow passage (111A); and a 
second closure unit (142) for closing the outflow passage (112) in an openable and 
closable manner.  
17717319_1 (GHMates) P108960.AU.1
Patent AU-2021203437-A1 (AU)
Title: PIN entry device
Inventor: NELSON GEORGINA
IPC: G06Q20/20
Filed: 2021-05-26
Abstract: There is disclosed a PIN entry device (PED) for electronic Point of Sale (EPOS) 
transactions. The PED has enhanced user /O functionality but retains the strict security 
and certification framework of such a device. In addition to the usual PED functionality, 
the PED disclosed herein allows feedback from a user to be obtained in response to a 
question. The PED comprises an alphanumeric display for displaying text to a user, a 
numeric keypad and one or more function keys. The PED is configured to operate to 
display text to the user on the alphanumeric display to prompt a response from the user.  
The displayed text corresponds to approved text and unapproved text. The PED is 
configured to accept responses entered on the numeric keypad or one or more function 
keys in response to approved text, and to accept only a single key press response when 
prompted by a display of unapproved text. A corresponding method is also disclosed.
WO 2016/071678 PCT/GB2015/053292 
1/3 
100 
10 
WWW 20 
Fig. 1
Patent AU-2021204568-A1 (AU)
Title: Methods, apparatuses, devices, and storage media for controlling game states
Inventor: WANG XINXIN
IPC: A63F1/00
Filed: 2021-06-25
Abstract: The present disclosure relates to a method, an apparatus, a device, and a storage medium 
for controlling game states. The method includes: determining, in response to that an interface 
call instruction is acquired, a target interface from a plurality of preset interfaces according to 
the interface call instruction, wherein each of the plurality of interfaces is encapsulated with a 
state switching condition; acquiring a current state of the game; and transferring the current 
state to the target interface, and switching the game to a target state according to a state 
switching condition encapsulated in the target interface and corresponding to the current state 
by calling the target interface.
Patent AU-2021206100-A1 (AU)
Title: Polycyclic compound acting as kinase inhibitor
Inventor: ZHANG HANCHENG
IPC: A61K31/4375
Filed: 2021-01-11
Abstract: Provided in the present invention is a polycyclic compound, which acts as a kinase inhibitor. Specifically, provided in the present invention is a compound of the structure shown in formula (I) below (each group is defined as specified in the specification), a pharmaceutical composition comprising a compound of formula (I), the compound, and an optical isomer, a pharmaceutically acceptable salt, a prodrug, a deuterated form, a hydrate, a solvate etc. of the compound. The compound can effectively inhibit a variety of kinases, including CDK and/or TRK, and can thus be used for treating various diseases related to tumors, etc.
Patent AU-2021207486-A1 (AU)
Title: Medical implant comprising two frame components and pairs of eyelets
Inventor: COLE DANIEL S
IPC: A61B17/00
Filed: 2021-01-14
Abstract: An implantable medical device comprising a first frame component. The first frame component including a first set of elongate elements configured to conform to an anatomy of a patient. The implantable medical device also comprising a second frame component including a second set of elongate elements configured to conform to an anatomy of a patient. The first frame component and the second frame component being discrete and separate from one another. The implantable medical device also comprising a conduit portion arranged between the first frame component and the second frame component. The conduit portion including a membrane connecting the first frame component and the second frame component.
Patent AU-2021208601-A1 (AU)
Title: Glp-1 compositions and uses thereof
Inventor: ENGELUND DORTHE KOT
IPC: A61K9/00
Filed: 2021-02-17
Abstract: The present invention relates to pharmaceutical compositions of the GLP-1 peptide semaglutide comprising no more than 0.1 %(w/w) phenol and above 6.4 mg/ml sodium chloride, their preparation, kits comprising such compositions as well as uses thereof.
Patent AU-2021220842-A1 (AU)
Title: Redundant steering system and machines and methods thereof
Inventor: MATE EDWARD WILLIAM
IPC: E02F9/22
Filed: 2021-02-11
Abstract: A redundant steering system comprises a primary power source; a secondary power source; first and second pumps operatively coupled to the primary and secondary power sources, respectively, to output first and second supplies of hydraulic fluid to a steering cylinder based on operation of the primary and secondary power source, respectively; first and second pairs of selector valves respectively coupled to the first and second pumps; and a charge circuit coupled to respective control inputs of the first and second pairs of selector valves to selectively supply hydraulic fluid to the control inputs of the first and second pairs of selector valves to stop hydraulic fluid from only one of the first pump and the second pump from being provided to the steering cylinder and to provide hydraulic fluid to the steering cylinder from only one of the other of the first pump and the second pump.
Patent AU-2021221473-A1 (AU)
Title: System and method for preparing a soft tissue graft
Inventor: KAM ANDREW
IPC: A61F2/08
Filed: 2021-08-24
Abstract: A system and method for loading a suture construct on a soft tissue graft with 
a graft assembly. In one aspect, the graft assembly includes a suture construct having 
a closed end (63) and an open end. A first tail (68) of suture (56) and a second tail (70 
of suture (56) is positioned adjacent to the open end. A first closed loop (60) is 
positioned at the closed end (63) formed from the first and second tails (68, 70) of 
suture (56). A first splice (62) is formed by the first tail (68) in the second tail (70) 
between the closed loop (60) and the open end. A second closed loop (60) is formed 
from the first and second tails (68,70) of suture between the first splice (62) and the 
open end, and a second splice (62) is formed by the first tail in the second tail between 
the second closed loop (60) and the open end.  
(Fig 4 to accompany abstract) 
Page 12 of 12 
3186634.4 8/24/2018
3(
Patent AU-2021221625-A1 (AU)
Title: A roller crusher
Inventor: REZNITCHENKO VADIM
IPC: B02C25/00
Filed: 2021-08-25
Abstract: The disclosure relates to a roller crusher that includes a frame, first and second crusher 
rolls arranged axially in parallel with each other and a deflection distributor. The roller crusher 
further includes at least one load sensor configured to detect a material load in the deflection 
distributor and at least one positioning sensor configured to detect a parameter pertaining to a 
distance between a first point and a second point of the roller crusher. At least the first point is 
defined on the deflection distributor or on one of movable bearing housings of the roller crusher.  
The disclosure further relates to a method for monitoring the physical condition of the deflection 
distributor and to a refitting kit for a roller crusher.  
28
12 1/8 
12' 3 
50 30 
3 31 28 10 
2 21 
11 24 
25,26 
13' 35' 103 
6 ' 30A 
50' 30B' 31' 0 20 
Fig. 1 281'1' 27" 1' 
10 24 ', 25', 26' 51 
21' 30A' 
112130B 3 4 3 3 
27 3 0 
100 2 
30C 
25,26 24 6 5 
Fig. 2
Patent AU-2021237732-A1 (AU)
Title: Method of forming and incorporating a polymeric lens within a lens housing
Inventor: BODOR PETER PAL
IPC: B29D11/00
Filed: 2021-03-21
Abstract: A method for forming a lens housing containing a polymeric lens including inserting a mandrel having a distal face with negative features of the desired polymeric lens into a cylinder and filling a reservoir formed between the distal face and a distal end of the cylinder with a curable polymeric lens material. The curable polymeric lens material is cured in place within the reservoir thereby forming the desired polymeric lens. The proximal surface of the polymeric lens is formed and shaped by the distal face of the mandrel, while the distal surface of the polymeric lens is dependent upon the amount of the curable polymeric lens material placed in the reservoir and the volume of the reservoir.
Patent AU-2021263813-A1 (AU)
Title: Pharmaceutical formulation
Inventor: CHRISTIAN TWINKLE R
IPC: A61K39/395
Filed: 2021-04-28
Abstract: The present disclosure describes stable aqueous formulations comprising, e.g., a bispecific antibody construct, a buffer, a saccharide and a surfactant, the formulation having a pH 4.8-5.5.
Patent AU-2021275777-A1 (AU)
Title: Exfoliation bar for shaving razor
Inventor: LETTENBERGER NEIL DUSTIN
IPC: B26B21/40
Filed: 2021-05-19
Abstract: An exfoliation bar (22) for a shaving razor (10) with a skin contacting footprint area of at least 30 mm
Patent AU-2021278701-A1 (AU)
Title: A battery connector
Inventor: BLAKSTAD SVEIN EVEN
IPC: H01M50/249
Filed: 2021-05-26
Abstract: A battery connector (7) for connecting a replaceable battery (6) to an aerial vehicle (1), comprising a housing (10) configured for fixing to one of the replaceable battery (6) and the aerial vehicle (1) and a connector element (14) comprising a first connection portion (15) configured for releasable connection to an external connection element (4) of the other one of the replaceable battery (6) and the aerial vehicle (1). The connector element (14) further comprising a second connection portion (18) configured for fixed connection to the replaceable battery (6) or the aerial vehicle (1) to which the housing (10) is configured to be fixed. The connector element (14) is supported in a horizontal direction (XY) in the housing (10) by at least one flexible element (19) positioned at least partly between the connector element (14) and the housing (10), such that there is space between the connector element (14) and the housing (10) in the horizontal direction (XY). The connector element (14) is supported in a vertical direction (Z) in the housing (10) by an upper flexible element (21) positioned between an upper part (23) of the connector element (14) and the housing (10) and a lower flexible element (22) positioned between a lower part (24) of the connector element (14) and the housing (10), such that there is space between the connector element 14 and the housing (10) in the vertical direction (Z).
Patent AU-2021283683-A1 (AU)
Title: Method and system for training a neural network-implemented sensor system to classify objects in a bulk flow
Inventor: BALTHASAR DIRK
IPC: G06V10/00
Filed: 2021-06-02
Abstract: The present disclosure relates to a method (100) of training a neural network (NN) stored on a computer-readable storage medium (10) to classify objects (A-E) in a bulk flow, the method (100) comprising the steps of: providing (101) input image data (50*) depicting objects (A*-E*) to be classified, which input image data (50*) is captured by means of an input imaging sensor (30, 30a-30e) of a first sensor technology design; providing (102) auxiliary image data (50**), which auxiliary image data (50**) is captured by means of an auxiliary imaging sensor (40, 40a-40e) of a second sensor technology design, and which auxiliary image data (50**) depicts said or similar objects (A**-E**) which are classified in accordance with a predetermined classifying scheme; by means of a processing unit (20), train (103) the neural network (NN) stored on the computer-readable storage medium (10) to classify the depicted objects (A*-E*) in the input image data (50*) based on classifications of depicted objects (A**-E**) in the auxiliary image data (50**), wherein the depicted objects (A*-E*) in the input image data (50*) correspond to objects (A-E) in a bulk flow, and wherein the second sensor technology design is different from the first sensor technology design.
Patent AU-2021290281-A1 (AU)
Title: Inhaler
Inventor: WACHTEL HERBERT
IPC: A46B11/00
Filed: 2021-12-22
Abstract: This invention relates to an inhaler, preferably for insertion into a nostril, in 
particular a horse's nostril, with an inhalation valve, which has a valve body seat 
and an annular valve element which is deflectable off of the valve body seat only 
at an inner edge, and a stop for limiting maximum deflection of the inner edge of 
the valve element, and a discharge nozzle for producing an aerosol. The valve 
body seat has a sealing edge which forms an opening to accommodate the 
discharge nozzle wherein an opening of the discharge nozzle is arranged 
downstream from the valve body seat. The valve element is secured on an outer 
edge remote from the discharge nozzle so that the outer edge remains fixed when 
the inner edge is deflected off of the valve body seat.
Patent AU-2021300260-A1 (AU)
Title: 5-[5-(piperidin-4-yl)thieno[3,2-c]pyrazol-2-yl]indazole derivatives and related compounds as modulators for splicing nucleic acids and for the treatment of proliferative diseases
Inventor: REYNOLDS DOMINIC
IPC: A61K31/407
Filed: 2021-07-02
Abstract: The present disclosure features compounds e.g. of formula (I-a) and similar compounds e.g. of formulae (l-g), (l-i), (l-j), (III), (lll-a), (III- b) and (IV) disclosed herein and other related compounds, and pharmaceutical compositions thereof. The present disclosure further discloses said compounds and their compositions for use in methods of modulating nucleic acid splicing, as well as said compounds for use in methods of treating e.g.: • proliferative diseases, such as e.g. cancer, benign neoplasms or angiogenesis, • neurological diseases or disorders, such as e.g. Huntington's disease, • autoimmune diseases or disorders, immunodeficiency diseases or disorders, lysosomal storage disease or disorder, cardiovascular diseases or disorders, metabolic diseases or disorders, respiratory diseases or disorders, renal diseases or disorders, or infectious diseases. Exemplary compounds are e.g. 5-[5-(piperidin-4-y l)thieno[3,2- c]pyrazol-2-yl]indazole and 5-[2-(piperidin-4-yl)-[1,2,4]triazolo[3,2-b] [1,3]thiazol-5-yl]indazole derivatives and related compounds.
Patent AU-2021304762-A1 (AU)
Title: Novel polypeptide and therapeutic use thereof
Inventor: HAN JIE
IPC: C07K14/605
Filed: 2021-07-06
Abstract: The present invention relates to the field of polypeptide chemistry, specifically to a polypeptide compound and use thereof in medical treatment.
Patent AU-2021329337-A1 (AU)
Title: Systems and methods for tuning optical cavities using machine learning techniques
Inventor: NAMAZI MEHDI
IPC: G02B26/00
Filed: 2021-08-18
Abstract: An optical system including an optical cavity and a method of tuning an optical cavity using a machine learning model is provided. The method includes determining a tuning parameter of the optical cavity by: analyzing, using a convolutional neural network (CNN) model, a measurement signal obtained from the optical cavity to determine a degree of misalignment of the optical cavity; and determining, using a reinforcement learning (RL) model, the tuning parameter based on the degree of misalignment of the optical cavity.
Patent AU-2021376306-A1 (AU)
Title: In-process verification of calibration status of pH probes
Inventor: NATARAJAN VENKATESH
IPC: C07K1/22
Filed: 2021-11-09
Abstract: Automated systems and methods for low-pH viral inactivation include adding an elution pool to a first vessel with an acid. Once first vessel pH probes measure sufficiently low pH, the pool is transferred to a second vessel, where the pH is checked again, and the pool is held for a time sufficient to reduce virus concentration to a safe level, and neutralized, filtered, and transferred to a third vessel. Meanwhile, the first vessel is filled with a known-pH buffer, which is checked against readings from first vessel pH probes to determine whether recalibration is needed. After the pool is transferred to the third vessel, the second vessel is filled with a known-pH buffer, which is checked against readings from second vessel pH probes to determine whether recalibration is needed. The process repeats when the known-pH buffer is dumped and a new elution pool is added to the first vessel.