baber/WOPTO huggingface dataset:
Patent CA-3062663-A1 (CA)
Title: Systems and methods for rail worker and rail vehicle warning and position determination
Inventor: FISHER DOUGLAS G
IPC: B61L25/02
Filed: 2019-11-26
Abstract: ABSTRACT System and methods are provided for warning a worker of a rail vehicle, or an operator of the rail vehicle of the worker. The system includes a worker device, a vehicle device, and a central server. The devices and server operate on one or a combination of actual or simulated satellite navigational signals, and beacon signals to determine the position of the devices, to generate a warning. The position determination may prioritize beacon signals over satellite navigation signals. The position determination may involve correcting a calculated position based on a measured power level of the beacon signal received from the beacon transmitter, an elapsed time since a previous beacon signal was last received by the device from the beacon transmitter, an elapsed time since a previous satellite navigation signal was received by the device, or an accuracy of the position of the device based on the satellite navigation signal.
Patent CA-3064443-A1 (CA)
Title: Anticorps humanises anti-globo h et leurs utilisations dans des traitements du cancer
Inventor: WU CHIA-CHENG
IPC: C07K16/30
Filed: 2018-05-24
Abstract: L'invention concerne un anticorps anti-Globo H humanisé, ou un fragment scFv ou Fab de celui-ci, comprenant un domaine variable à chaîne lourde ayant trois régions complémentaires constituées de HCDRl, HCDR2, et HCDR3 et un domaine variable de chaîne légère ayant trois régions complémentaires constituées de LCDRl, LCDR2, et LCDR3, la séquence de HCDRl étant GYISSDQILN (SEQ ID NO:4), la séquence de HCDR2 étant RIYPVTGVTQYXHKFVG (SEQ ID NO:5, où X est un acide aminé quelconque), et la séquence de HCDR3 est GETFDS (SEQ ID NO:6), la séquence de LCDRl étant KSNQNLLX' SGNRRYZLV (SEQ ID NO:7, où X' est F, Y ou W, et Z représente C, G, S ou T), la séquence de LCDR2 est WASDRSF (SEQ ID NO:8), et la séquence de LCDR3 est QQHLDIPYT (SEQ ID NO:9).
Patent CA-3065878-A1 (CA)
Title: Method, device and computer program for virtually adjusting the spectacle frame
Inventor: SCHWARZ OLIVER
IPC: G06T17/00
Filed: 2018-06-01
Abstract: Disclosed are methods, computer programs and devices for a virtual try-on process for spectacles, using approximate- and precise adjustment. Provided for this purpose are 3D models of a head and a spectacle frame and head metadata based on the model of the head and frame metadata based on the model of the frame. The head metadata comprises placement information, in particular a placement point, which can be used for the approximate positioning of the spectacle frame on the head, and/or a placement region which describes a region of the arm of the frame for placement on the ears of the head. A rapid and relatively simple computational positioning of the spectacle frame on the head and a more accurate positioning using a subsequent precise adjustment can be achieved with the aid of metadata of this type.
Patent CA-3066084-A1 (CA)
Title: Methodes de traitement de la fibrose kystique
Inventor: HASELTINE ERIC L
IPC: A61K31/454
Filed: 2018-06-08
Abstract: L'invention concerne un composé I de formule (formule), un sel pharmaceutiquement acceptable du composé I, des compositions pharmaceutiques contenant au moins un composé I et des procédés de traitement de la fibrose kystique comprenant l'administration d'au moins un composé I, des compositions pharmaceutiques contenant un sel pharmaceutiquement acceptable d'au moins un composé I et des méthodes de traitement de la fibrose kystique comprenant l'administration d'un sel pharmaceutiquement acceptable d'au moins un composé I.
Patent CA-3066930-A1 (CA)
Title: Prognostic indicators of poor outcomes in praegnant metastatic breast cancer cohort
Inventor: SZETO CHRISTOPHER
IPC: G16B5/00
Filed: 2018-06-15
Abstract: Transcriptomics data from tumor tissue of patients diagnosed with metastatic breast cancer are clustered and associated with overall survival of the patients. A subset of genes from one of the cluster associated with poor outcome are used to generate a survival prediction model predicting a survival time based on expression levels of a plurality of genes. Using such generated survival prediction model, a survival time of a patient diagnosed with metastatic breast cancer can be predicted and a treatment regimen can be updated or generated based on the survival time.
Patent CA-3067161-A1 (CA)
Title: Filler composition indicating readiness to sand
Inventor: TWARDOWSKA HELENA
IPC: C09D7/41
Filed: 2018-07-17
Abstract: A vehicle bond filler formulation is provided that includes a part A having curable resin and a monomer reactive diluent. A part B storage- separate, cure initiator package contains a free-radical cure initiator. At least one color changing dye adapted to change color upon mixing the part A and the part B and within +5 minutes of cure of the curable resin to a sandable condition is present in either the part A or a separate part C, a guide coat colorant, or a combination thereof. A process of for repairing a vehicle body is also provided that includes mixing a part A containing the at least one color changing dye with the part B to form an internal guide coat mixture applied to a substrate of the vehicle body in need of repair. The mixture cures causing the color changing dye to the terminal change color within +5 minutes of cure of the curable resin to a sandable condition.
Patent CA-3072221-A1 (CA)
Title: Splice switching oligomers for tnf superfamily receptors and their use in treatment of disease
Inventor: ORUM HENRIK
IPC: C07H21/00
Filed: 2007-10-19
Abstract: The present invention relates to splice switching oligonucleotides or splice switching oligomers (SSOs).  The preferred SSOs according to the invention target exon 7 of TNFRI  (TNFRSFIA) or TNFR2 (TNFRSFIA) pre-mRNA, typically resulting in the production of TNFR variants which comprise a deletion in part or the entire exon 7 respectfully. SSOs targeting exon 7 are found to result in a soluble form of the TNFR, which has thereputic benefit for treatment of inflammatory diseases. The SSO's are characterized in that they are substantially incapable or incapable of recruiting RNaseH.
Patent CA-3072859-A1 (CA)
Title: Chimeric antigen receptor and car-t cells that bind cxcr5
Inventor: HOPKEN UTA
IPC: C07K16/28
Filed: 2018-08-23
Abstract: The invention relates to an isolated chimeric antigen receptor polypeptide (CAR), wherein the CAR comprises an extracellular antigen-binding domain, comprising an antibody or antibody fragment that binds a human CXC chemokine receptor type 5 (CXCR5) protein. The invention further relates to a nucleic acid molecule encoding the CAR of the invention, a genetically modified immune cell, preferably a T cell, expressing the CAR of the invention and the use of said cell in the treatment of a medical disorder associated with the presence of pathogenic cells expressing CXCR5, preferably pathogenic mature B cells and/or memory B cells, and/or pathogenic T cells and/or T follicular helper cells, in particular mature B cell non-Hodgkin's lymphoma (B-NHL), T cell non-Hodgkin's lymphoma, or autoantibody-dependent autoimmune disease, preferably selected from systemic lupus erythematosus (SLE) or rheumatoid arthritis.
Patent CA-3074199-A1 (CA)
Title: Modified sulfuric acid and uses thereof
Inventor: PURDY CLAY
IPC: C09K3/00
Filed: 2020-02-28
Abstract: A modified aqueous acid composition comprising: sulfuric acid; a compound comprising an amine moiety and a sulfonic acid moiety; and a peroxide; wherein sulfuric acid, said compound comprising an amine moiety and a sulfonic acid moiety and said peroxide are present in a molar ratio of no less than 1:1:1.  Also disclosed are methods of using such compositions.
Patent CA-3075691-A1 (CA)
Inventor: WOLKOW ROBERT A
IPC: G06N3/08
Filed: 2018-09-28
Abstract: L'invention concerne un procédé destiné à la formation de motifs et la commande d'électrons individuels sur une surface, qui comprend la mise en uvre d'une lithographie à l'hydrogène par microscopie à effet tunnel à balayage utilisant un microscope à sonde à balayage pour former des structures de charge comptant au moins une charge confinée ; la réalisation d'une série de mesures de microscopie à force atomique sans champ sur les structures de charge selon différentes hauteurs de pointe, l'interaction entre la pointe et la charge confinée étant élucidée ; et le réglage de hauteurs de pointe pour positionner de manière réglable des charges à l'intérieur des structures, pour écrire un état de charge donné. La présente invention concerne également une machine de distribution de Gibb, formée selon le procédé de formation de motifs et de commande d'électrons individuels sur une surface. L'invention concerne également un générateur de nombres aléatoires vrais multi-bits et un matériel d'apprentissage de réseau neuronal formé selon le procédé décrit ci-dessus.
Patent CA-3076072-A1 (CA)
Title: Locking folding arm detent mechanism for multirotor aircraft
Inventor: GIBSON GORDON
IPC: B64C27/08
Filed: 2020-03-17
Abstract: This disclosure describes a detent alignment mechanism consisting of a flexible plate and a lock plate arranged such that displacement of the flexible plate will release the interengagement and allow the lock plate to change position. The mechanism may provide one or more indexed locked positions. The geometry of the design allows the lock plate to move freely until a detent interengagement occurs. Displacing the flexible plate will allow the lock plate to be moved until the next engagement. In one application of the mechanism adapted to a multirotor aircraft (RPAS, drone, UAV) with arms extending horizontally from the fuselage, the invention allows the drone arms to fold against the fuselage for transportation and extend to the flight position smoothly and reliably without the use of tools or fasteners. The design provides a high strength, secure rotary joint for multirotor aircraft with specific geometries suited to 3, 4, 6 and 8 arm configurations.
Patent CA-3076659-A1 (CA)
Title: Intermediate concrete anchor system with cap
Inventor: SORKIN FELIX
IPC: E04C3/293
Filed: 2020-03-20
Abstract: A method and system for forming a post-tensioned concrete slab using a post-tensioning concrete anchor. The system may comprise a connector anchor including a bore that includes a first frustoconical portion, and the connector anchor may be adapted to bear on the post-tensioning concrete anchor. The system may also comprise a coupler comprising a connector and a coupler body that includes a second frustoconical portion that is oriented oppositely to the first frustoconical portion. The connector may have a bore therethrough and may be configured to receive the coupler body and to engage the connector anchor. A pocket-forming cap may releasably engage the post-tensioning concrete anchor; the pocket-forming cap may include a frustoconical wall, a gripping head, and a connector-receiving portion. The method may include using the system to form a second concrete section adjacent to a first concrete section before stressing the first concrete section.
Patent CA-3077592-A1 (CA)
Title: Battery thermal management manifold segment and assembly thereof
Inventor: JONES CARL
IPC: B60L50/50
Filed: 2018-10-05
Abstract: A battery thermal management manifold segment is used amid the circulation of thermal management fluid to help regulate temperatures in a battery of an electric vehicle (EV). The battery thermal management manifold segment has one or more tubes ? a feed tube, a return tube, or both ? that have an inlet, an outlet, and a passage spanning therebetween. The tube(s) has one or more branch tubes extending therefrom. The branch tube(s) has a branch passage spanning from the passage of the tube(s).
Patent CA-3079336-A1 (CA)
Inventor: GERIAVENKO ROSTYSLAV
IPC: E04F10/08
Filed: 2020-04-23
Abstract: A louvered pergola includes (a) a plurality of posts; (b) an elevated frame supported by the posts and defining a central frame opening; and (c) a plurality of louvers supported by the frame and extending parallel with each other across the frame opening. The plurality of louvers includes a first louver fixed to the frame, a second louver fixed to the frame opposite the first louver, and a plurality of pivotable louvers pivotably supported by the frame between the first and second louvers. The pivotable louvers pivotable between a closed position in which the plurality of louvers partially overlap with each other to close the frame opening and an open position in which a gap is provided between adjacent louvers of the plurality of louvers.
Patent CA-3082180-A1 (CA)
Inventor: SIMHA HARI
IPC: B25J15/00
Filed: 2020-06-01
Abstract: A soft gripper comprising at least one actuator, the at least one actuator comprising: a top layer and a bottom layer; wherein the top layer comprises at least one fluid chamber comprising a plurality of compartments separated from each other and interconnected to induce flexion upon introduction of a fluid into the at least one fluid chamber; and wherein the bottom layer comprises an auxetic structure adaptable to conform to an object being grasped.
Patent CA-3082296-A1 (CA)
Inventor: GERVAIS FRANCOIS
IPC: G06N3/02
Filed: 2020-06-08
Abstract: Method and environment controller predicting temperature variations based on sound level measurements. The environment controller determines N consecutive sets of frequency domain sound level measurements.  Each set of frequency domain sound level measurements comprises a given number M of sound level amplitudes at the corresponding given number M of frequencies.  The environment controller executes a neural network inference engine using a predictive model for inferring one or more output based on inputs. The inputs comprise the N consecutive sets of frequency domain sound level measurements.  The one or more output comprises a predicted variation of a temperature. For example, the environment controller receives a plurality of consecutive time domain sound level measurements from a sound sensor and generates the N consecutive sets of frequency domain sound level measurements based on the plurality of consecutive time domain sound level measurements (for instance by using a Fast Fourier Transform algorithm).
Patent CA-3085455-A1 (CA)
Title: Forme pharmaceutique orale solide comprenant de la linagliptine
Inventor: TURKYILMAZ ALI
IPC: A61K31/522
Filed: 2018-12-14
Abstract: La présente invention concerne une forme pharmaceutique orale solide comprenant de la linagliptine et au moins un liant.
Patent CA-3088773-A1 (CA)
Inventor: COOPERSMITH ALLAN
IPC: A61D5/00
Filed: 2018-05-31
Abstract: Animal consumable dental hygienic device, comprising: body with an exterior surface and an interior cavity, and sized to be bitten by animal. Exterior surface defines projections. Recesses extend inward from the exterior surface. Each recess has dental-hygienically active dimensions allowing a tooth to penetrate therein such that material surrounding the recess frictionally engages an outer surface of the tooth and scrapes the tooth to remove dental plaque. Projections are positioned, dimensioned, shaped and structured to be dental- hygienically active when the animal bites the body, allowing the tooth of the animal to be adjacent to at least one projection when the animal bites the body, such that a projection frictionally engages at least one of the outer surface of the tooth and gums of the animal during biting of the body by the animal.
Patent CA-3090223-A1 (CA)
Title: Compositions de revetement
Inventor: POLLUM JR
IPC: C09D163/00
Filed: 2018-12-10
Abstract: L'invention concerne une composition comprenant : un composant contenant de l'époxy, des particules élastomères en une teneur supérieure de 11 % en poids à 25 % en poids sur la base du poids total de la composition ; et un composant de durcissement pouvant être activé par une source d'énergie externe, le composant de durcissement comprenant au moins une guanidine ayant une taille de particule D90 de 25 µm mesurée par diffusion de lumière dynamique. L'invention concerne également la composition dans un état au moins partiellement durci. L'invention concerne également un procédé de traitement d'un substrat comprenant l'application de la composition sur une surface d'un substrat ; et l'application d'une source d'énergie externe pour durcir la composition. L'invention concerne également des substrats comprenant ladite composition. L'invention concerne également des substrats formés par le procédé de la présente invention.
Patent CA-3090794-A1 (CA)
Inventor: NAGAI KAZUKI
IPC: H04M3/53
Filed: 2018-06-28
Abstract: Il est décrit une méthode denregistrement dappels. Pour ouvrir une session denregistrement entre téléphones de protocole Internet, un téléphone de protocole Internet hôte transmet une demande douverture de session denregistrement à un serveur denregistrement, laquelle demande comprend des informations téléphoniques identifiant le téléphone de protocole Internet hôte et le téléphone de protocole Internet dune partie jointe. Par suite de la réception de la demande, le serveur se réfère aux informations téléphoniques de la demande pour déterminer si la demande a déjà été présentée par le téléphone de protocole Internet de la partie jointe. Dans la négative, le serveur ouvre une session denregistrement avec le téléphone de protocole Internet hôte et détermine un paramètre en vue denregistrer les données audio de lappel transmis par le téléphone de protocole Internet. Dans la positive, le serveur refuse la demande et nouvre pas de session denregistrement avec le téléphone de protocole Internet hôte ayant présenté la demande.
Patent CA-3095280-A1 (CA)
Inventor: YANAGISAWA MASANOBU
IPC: A23L11/00
Filed: 2019-03-22
Abstract: The purpose of the present invention is to provide a method for manufacturing a soybean paste food or gel food that has a good taste and favorable smooth texture. It was found that a soybean paste food or gel food that has a good taste and favorable smooth texture can be obtained by statically heating a liquid food comprising a dietary fiber-containing soybean emulsion composition, said dietary fiber-containing soybean emulsion composition having a dietary fiber content of 2.5 wt% or more, a protein content of 25 wt% or more in terms of dry matter, a lipid content (the content of an extract with a chloroform/methanol mixture solvent) of 25 wt% or more in terms of dry matter, an average particle diameter of 10-100 µm, a moisture content of 70-90 wt%, and a viscosity of 3000 mPa.s or lower.
Patent CA-3095438-A1 (CA)
Inventor: VANGELISTI MANUEL
IPC: A61K39/12
Filed: 2019-04-02
Abstract: L'invention concerne une souche de virus de la fièvre jaune vivant atténué adaptée pour croître sur des cellules Vero à partir d'une sous-souche 17D du virus de la fièvre jaune parent qui n'est pas adaptée à croître sur des cellules Vero, ladite souche de virus de la fièvre jaune vivant atténué étant moins neurovirulente que ladite sous-souche 17D du virus de la fièvre jaune parent.
Patent CA-3097884-A1 (CA)
Inventor: SHETTY DINESH ANANDA
IPC: E21B43/30
Filed: 2020-11-03
Abstract: When a child well is hydraulically fractured near the depleted reservoir volume surrounding a previously produced parent well, it is economically efficient to deliver proppant to the formation volume and fractures not reached by the parent well. A fracture length, which is the distance fluid travels from the child well to the depleted region, is calculated as a function of fracture stage. From identified trends in fracture length, fracture length for future stages can be predicted. Based on predicted fracture length, the slurry or treatment volume to cause well interference can be estimated. Proppant concentration or fracturing stage design can be adjusted so that the well interference volume is larger than the treatment volume and proppant is efficiently delivered to the child well fractures.
Patent CA-3099119-A1 (CA)
Inventor: GEISTLINGER TIMOTHY
IPC: C07K14/76
Filed: 2019-04-30
Abstract: L'invention concerne des polymères de monomères de protéines lactiques, des procédés de fabrication de tels polymères, et des compositions comprenant de tels polymères.
Patent CA-3104868-A1 (CA)
Title: Molecules d'amelioration de signaux wnt specifiques au tissu et leurs utilisations
Inventor: ZHANG ZHENGJIAN
IPC: C07K16/28
Filed: 2019-07-09
Abstract: La présente invention concerne des molécules d'amélioration de signaux Wnt spécifiques au tissu, et des procédés d'utilisation associés de ces molécules pour améliorer la signalisation Wnt dans des tissus hépatiques.
Patent CA-3105665-A1 (CA)
Title: Fire spread-limiting assembly and fire spread-limiting method
Inventor: BOUSSIAM EL BOURAKADI MOHAMMED
IPC: A62C2/10
Filed: 2021-01-12
Abstract: The present disclosure concerns a fire spread-limiting assembly comprising a heat resistant covering; and a cooling fluid circulation assembly comprising: a cooling fluid source integrated to the heat resistant covering, one or more flexible fluid lines being part of the heat resistant covering, and a pump fluidly connected to said one or more flexible fluid lines and to the cooling fluid source and configured to circulate the cooling fluid within said one or more flexible fluid lines upon actuation. There is also disclosed a method for limiting a spread of a fire.
Patent CA-3108876-A1 (CA)
Title: Cell-penetrating peptides
Inventor: WOOD MATTHEW
IPC: C07K14/00
Filed: 2019-08-09
Abstract: The present invention relates to peptides, in particular cell-penetrating peptides, and to conjugates of such cell-penetrating peptides with a therapeutic molecule. The present invention further relates to use of such peptides or conjugates in methods of treatment or as a medicament, especially in the treatment of genetic disorders and in particular muscular dystrophies such as Duchenne muscular dystrophy.
Patent CA-3109101-A1 (CA)
Inventor: MASUDA KENJI
IPC: C12N15/113
Filed: 2019-08-08
Abstract: The present invention provides a means for increasing the production of a foreign protein which will serve as a protein medicinal preparation, in a host cell, such as a mammal-derived cultured cell. The present invention provides a transformed cell having a novel promotor for the Hspa8 gene, and a method for producing a foreign protein through high-level secretion using the transformed cell.
Patent CA-3109318-A1 (CA)
Title: Settling tank and methods for guiding partial flows in the inflow area of settling tanks
Inventor: ARMBRUSTER MARTIN
IPC: B01D21/24
Filed: 2019-08-12
Abstract: Inlet structures arranged within settling tanks, through the inlet opening of which the suspension to be separated flows to the tanks, the height of which can be variably adjusted. The volume flow flowing out of the inlet structure can, depending on the current load, be directed by forming a horizontally flowed through inlet opening or a vertically flowed through inlet opening and can optionally be divided into horizontal and vertical partial flows Qi and Qn. As a result of the horizontal inflow, the capacity of the settling tank increases at high load, and as a result of the vertical inflow, the amount of the volume flow directed through the settling chamber as well as the turbulent energy within the settling chamber decrease at low load, so that the retention of fine suspended particles within the settling tank is increased and thus the effluent quality is improved.