baber/WOPTO huggingface dataset:
Patent AU-2021403263-A1 (AU)
Title: Bispecific antibody for specifically neutralizing tgf-β signal of helper t cell, and pharmaceutical combination and use thereof
Inventor: CHENG HANBING
IPC: C07K16/46
Filed: 2021-06-25
Abstract: The present invention relates to the technical field of biology, and particularly relates to a bispecific antibody for specifically neutralizing a TGF-β signal of a helper T cell. The bispecific antibody at least comprises a first protein chain and a second protein chain, wherein the first protein chain comprises a part or all of the structure of a first protein functional region, and/or a part or all of the structure of a second protein functional region. The first protein functional region targets CD4 and the second protein functional region targets TGFβ1. The optimized anti-CD4/anti-TGF-β1 bifunctional antibody can efficiently neutralize a TGF-β signal of a helper T cell with high affinity, avidity and specificity. Specifically, the optimized anti-CD4/anti-TGF-β1 bifunctional antibody, represented in the form of IgG-(L)-ScFv, can inhibit the TGF-β signal pathway of the helper T cell with a higher neutralizing efficacy, and can achieve the same cancer inhibiting effect with a lower drug concentration, so that the bifunctional antibody becomes an ideal candidate for therapeutic application.
Patent AU-2021403588-A1 (AU)
Title: Luminaire head with a removable cap
Inventor: BUDAVÁRI PÉTER
IPC: H02G3/16
Filed: 2021-12-15
Abstract: Luminaire head comprising: a housing having a cap opening, a removable cap for closing the cap opening of the housing, said removable cap having an inner side and an outer side, one or more connectors provided to the inner side of the removable cap for connecting at least a first wiring to a second internal wiring of the luminaire head.
Patent AU-2021409989-A1 (AU)
Title: Hybrid heat exchanger
Inventor: GUY ERIC
IPC: F28F21/06
Filed: 2021-12-22
Abstract: In one aspect, a hybrid heat exchanger that includes a metallic serpentine tube having an inlet end portion to receive a process fluid, an outlet end portion, and a series of runs and return bends directing the process fluid from the inlet end portion to the outlet end portion of the metallic serpentine tube. The hybrid heat exchanger further includes a thermally conductive polymer body thermally integrated with the serpentine tube. The thermally conductive polymer body has an outer surface to be contacted by a fluid, such as air and/or water. The thermally conductive polymer body is configured to transfer heat between the metallic serpentine tube and the fluid contacting the outer surface of the thermally conductive polymer body. The outer surface of the thermally conductive polymer body includes surface enhancement features that affect flow of the fluid across the outer surface of the thermally conductive polymer body.
Patent AU-2021413371-A1 (AU)
Title: Irak degraders and uses thereof
Inventor: MAINOLFI NELLO
IPC: C07C23/36
Filed: 2021-12-30
Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
Patent AU-2021414253-A1 (AU)
Title: Series of piperidine-substituted benzoic acid compounds, and use thereof
Inventor: CHEN KEVIN X
IPC: C07D401/06
Filed: 2021-12-30
Abstract: A series of piperidine-substituted benzoic acid compounds and the use thereof, and specifically disclosed is a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.
Patent AU-2021427965-A1 (AU)
Title: Indoor unit for air conditioner
Inventor: NUNOME YOSHINORI
IPC: F24F1/008
Filed: 2021-10-25
Abstract: Provided is an indoor unit for an air conditioner, capable of preventing the interior of the indoor unit from being in a high humidity state for a long period of time. The present invention comprises: a housing (10) that has a space (13) formed inside and an air outlet (11) communicating between the space (13) and the outside; a flap (20) that opens and closes the air outlet (11); an ozone generator (40) that is disposed in the space (13); and a control unit. After the cooling or dehumidification operation is stopped, the control unit generates ozone from the ozone generator (40) when the air outlet (11) is in the open state, not closed by the flap (20).
Patent WO-2022183245-A1 (WO)
Title: A hyper-scale cloud environment standard control deviation remediation application
Inventor: MODESTO LORENZO
IPC: G06F9/455
Filed: 2022-03-03
Abstract: An application installable in a hyper-scale cloud environment has a remediation playbook comprising at least one remediation having at least one action for a standard control. The application serves a configuration interface for configuring a response level and a listener. In use, the application receives an alert from a SIEM of the Hyper-scale cloud environment, identifies the remediation using the alert and implements the action of the remediation depending on the response level.
Patent WO-2023197022-A1 (WO)
Title: Goulotte de mélange
Inventor: QIN GUOFANG
IPC: B65G11/08
Filed: 2022-04-12
Abstract: La présente invention concerne une goulotte comprenant un corps de goulotte ayant une entrée pour recevoir un matériau d'agrégat et un orifice d'évacuation pour distribuer le matériau d'agrégat en aval ; et deux structures de réception ou plus disposées entre l'entrée et l'orifice d'évacuation, chaque structure de réception comprenant une plateforme pour recevoir le matériau d'agrégat à partir de l'entrée ; et les structures de réception étant séparées par un espace.
Patent AU-2022210871-A1 (AU)
Title: Devices, systems and methods of informational signal synchronization using a reference signal
Inventor: RICHARZ WERNER G
IPC: G08C13/02
Filed: 2022-01-20
Abstract: An example method includes: recording, at a first sensor device, (i) a first informational signal as detected at the first sensor device; and (ii) a reference signal as detected at the first sensor device; recording, at a second sensor device (i) a second informational signal as detected at the second sensor device; and (ii) the reference signal as detected at the second sensor device; determining a time shift between the reference signal as recorded by the first sensor device and the reference signal as recorded by the second sensor device; and applying the determined time shift to the second informational signal to time-align the first informational signal and the second informational signal.
Patent AU-2022214075-A1 (AU)
Title: Linear media handling system and devices produced using the same
Inventor: KNIERIM GLENN
IPC: H01F6/06
Filed: 2022-01-25
Abstract: An improved system for handling delicate linear media and in particular to a method and apparatus for winding delicate linear media such as superconducting wire or tape or optical fibers onto a spool or former, and electric machines produced thereby. A combination of direct closed loop control and media routing design facilitates the handling of the delicate media without causing damage. The axial tension in the linear media may be closely controlled during winding by means of feedback control loop using tension measurements to control the rotation speeds of the wind-from and wind-to spools. Further, during winding, the delicate linear media is only exposed to large radius bends with no reverse bending. Finally, output devices and features, commercial or otherwise, made possible by delicate linear media handling are revealed. This includes advanced SC devices and features.
Patent AU-2022215217-A1 (AU)
Title: Conjugation linkers containing 2,3-diaminosuccinyl group
Inventor: ZHAO ROBERT YONGXIN
IPC: A61P31/00
Filed: 2022-08-10
Abstract: Provided is a conjugate of a cytotoxic drug/molecule to a cell-binding molecule with a bis-linker (adual
linker) containing a 2, 3-diaminosuccinyl group. It also relates to preparation of the conjugate of a cytotoxic 
drug/molecule to a cell-binding molecule with the bis-linker, particularly when the drug having functional 
5 groups of amino, hydroxyl, diamino, amino-hydroxyl, dihydroxyl, carboxyl, hydrazine, aldehyde and thiol 
for conjugation with the bis-linker in a specific manner, as well as the therapeutic use of the conjugates.
Patent AU-2022226382-A1 (AU)
Title: Applicator head with dosing aid
Inventor: SABHERWAL AMIT
IPC: A45D34/04
Filed: 2022-02-22
Abstract: There is provided an applicator head (10) for administration of a topical formulation, comprising a dosing aid for application of a predefined dose of the topical formulation. The applicator head (10) comprises an applicator surface (20) adapted to apply the topical formulation to a user's skin. The applicator surface (20) comprises an outlet opening (40). The dosing aid comprises a dose marking, or dose markings (60, 60', 60'', 62', 62'') on the applicator surface (20), and wherein the dose marking (60, 60', 60'', 62', 62'') circumscribes an inner dosing compartment (64) that serves to measure the predefined dose of the topical formulation, and wherein the outlet opening (40) is disposed inside the inner dosing compartment.
Patent AU-2022253584-A1 (AU)
Title: Device and method for anti-tachycardia pacing
Inventor: BEN DAVID TAMIR
IPC: A61N1/362
Filed: 2022-04-04
Abstract: A method of anti-tachycardia pacing via an implanted cardiac device, comprising: positioning at least one electrode of the implanted cardiac device at an intra-cardiac location; detecting a tachycardia episode; delivering, via the at least one electrode, anti-tachycardia pacing pulses, wherein an anti-tachycardia pacing pulse comprises at least one of: a duration of between 5-10msec and an amplitude of between 7.5-10V.
Patent AU-2022258535-A1 (AU)
Title: A cellulose product toggle pressing module and method for using the same
Inventor: LARSSON OVE
IPC: B30B11/00
Filed: 2022-04-08
Abstract: A product forming unit (U) for manufacturing non-flat cellulose products (1) from an air-formed cellulose blank structure (2). The product forming unit (U) comprises a blank dry-forming module (4) with a moveable forming wire (4c), a toggle pressing module (6) with a toggle press (6a) and a forming mould (3), and an electronic control system (6h) operatively connected to the forming wire (4c) and the toggle press (6a). The blank dry-forming module (4) is configured for air-forming the cellulose blank structure (2) onto the forming wire (4c). The toggle press (6a) includes a pressing member (6d) movably arranged in a pressing direction, a toggle-mechanism (6e) drivingly connected to the pressing member (6d), a pressing actuator arrangement (6f) drivingly connected to the toggle-mechanism (6e). The forming mould (3) includes a moveable first mould part (3a) attached to the pressing member (6d) and a second mould part (3b). The electronic control system (6h) is configured for controlling operation of the pressing actuator arrangement (6f) for performing pressing operations, which involves driving the pressing member (6d) in the pressing direction by means of the toggle-mechanism (6e), and thereby forming the non-flat cellulose product from the air-formed cellulose blank structure by pressing the first mould part (3a) against the second mould part (3b). The electronic control system (6h) further is configured for intermittently feeding the forming wire (4c) between subsequent pressing operations.
Patent AU-2022269058-A1 (AU)
Title: Use of functionalized and non-functionalized ecms, ecm fragments, peptides and bioactive components to create cell adhesive 3d printed objects
Inventor: KAUR AMAN
IPC: A61L27/22
Filed: 2022-05-06
Abstract: Embodiments of this disclosure relate to bioinks and bioink compositions. These bioinks may be 3D printed into a hydrogel. The printed hydrogel may support primary cell and induced pluripotent stem cell attachment, proliferation, and spreading. Compounds in the bioink may be modified to incorporate chemical functionality, such as by chemical synthesis means. Incorporating chemical functionality may allow the incorporation of modified material as a component in the bioink. The modifications may allow chemical conjugation of a desired component. The desired component may maintain its cell interactive feature to aid in cell attachment and proliferation. Such incorporation may allow modulation of the bioprinted object's mechanical properties without interfering with cell adhesion.
Patent AU-2022273424-A1 (AU)
Title: Electronically activated sprinkler interlock
Inventor: JUTRAS IAN M
IPC: A62C37/40
Filed: 2022-05-10
Abstract: Fire suppression systems and methods are provided. The system can include an electronically activated sprinkler (EAS) interlock system to protect a target zone. The EAS interlock system can include a controller. The controller can be communicably coupled with a first detector and a second detector. The first detector can be disposed in an area outside the target zone. The second detector can be disposed inside the target zone. The controller can receive an input signal from the first detector indicating an event occurred prior to or in an absence of receipt of an input signal from the second detector. The controller can provide a hold command to at least temporarily inhibit a sprinkler inside the target zone from actuation based on receipt of the input signal from the first detector prior to or in the absence of receipt of the input signal from the second detector.
Patent AU-2022276997-A1 (AU)
Title: Microorganism producing purine nucleotides and method for producing purine nucleotides using the same
Inventor: LEE JI HYUN
IPC: C12N15/77
Filed: 2022-05-20
Abstract: The present application relates to a Corynebacterium stationis microorganism producing purine nucleotide, and a purine nucleotide production method using same, the microorganism having enhanced inorganic phosphate transporter system (Pit system) activity.
Patent AU-2022287600-A1 (AU)
Title: Location aware learning system for content dispensation for resource-constrained edge devices
Inventor: PODDER SANJAY
IPC: G06F16/909
Filed: 2022-12-14
Abstract: A learning system for automatically transmitting files according to user 
capabilities is provided. The learning system may include non-transitory memory 
storing instructions executable to transmit a file to a user device, and a processor 
circuitry configured to execute the instructions to determine a home base location of a 
user from at least one of a database storing user information of the user and the user 
device of the user. The processor circuitry further configured to calculate a travel 
distance from the home base location of the user to a hub circuitry of the learning 
system, determine a type of the file and an amount of content of the file based on the 
travel distance, and transmit, to the user device, the file according to the type of the 
file and the amount of content of the file.
6/8 
601 
Collect the available storage, 
home/dominant location & course 
completion status from the 
Negotiating Module 
4 _602 
Calculates the distance between 
the hub and home/dominant 
location using the least timdaking 
route (shortest / least traffic) 
_____________________________ 603 
Calculates the student's learning 
rate (Chapters/day) using last 
content dispense date, current 
date & course completion status 
604 
Is the 
YES calculated distanc& NO 
learning rate deviates much fro 
individual context 
values 
Send the calculated values of 605 
distance and learning rate to 607 Send the calculated values of 
'Individual Context' distance and learning rate to 
'Slice Dispenser' 
Calculate the new averages of 606 
distance & learning rate and 
update the 'Individual Context' 608 
'Slice Dispenser' 
FIG. 6
Patent AU-2022291580-A1 (AU)
Title: Power system for electric and hybrid vehicle and campervans
Inventor: DAVERN MICHAEL
IPC: B60L8/00
Filed: 2022-12-22
Abstract: A power system for an electric vehicle, the power system comprising at least one 
power generating device selected from a group consisting of a solar panel, a wind 
turbine capable of producing electrical power, an auxiliary generator driven by an 
internal combustion engine.  
The power system being further comprised of a charging device, a battery control 
device, at least one battery, a motor control device, an electric drive motor electrically 
connected to the motor control device, and a driver interface connected to the motor 
control device.  
The electric drive motor may be used to unfold the wind turbine to different state of 
deployment to generate power through regenerative wind turbine braking. The wind 
turbine may be fully unfolded outside the body of a vehicle or vehicle roof rack, while 
the vehicle is not in motion. The solar panel may be disposed outside the vehicle or as 
a separate section of a vehicle roof rack while remaining electrically connected to the 
charging device.  
the main sections comprising of the foldable wind turbine, a solar panel, a battery 
pack, can each be separate connected to form a single vehicle roof rack or be a 
embedded system, in or on the roof a electric vehicle, camper van, trailer, or building 
roof. The wind turbine in its folded down state sits above the solar panel but due to 
its design still allows light the reach its surface for the creation of electricity while the 
folded down wind turbine reduces its forward profile and its wind drag, while the 
vehicle is in motion. The internal combustion engine adds a further option for 
electrical energy production when required.
4-6 pages 
FIG 3B 
310 
300
Patent AU-2022315196-A1 (AU)
Title: Oral care compositions comprising hydroxyapatite
Inventor: ZHANG DENNIS
IPC: A61Q11/00
Filed: 2022-07-20
Abstract: Disclosed herein are oral care compositions comprising hydroxyapatite and a basic amino acid as well as methods of reducing or inhibiting enamel erosion, repairing enamel erosion damage, and/or increasing enamel microcrack or microscratch resistance using these compositions.
Patent AU-2023200340-A1 (AU)
Title: Threaded connection for steel pipe
Inventor: IWAMOTO MICHIHIKO
IPC: F16L15/04
Filed: 2023-01-23
Abstract: A threaded connection for steel pipe is provided that can be made up 
quickly and appropriately. The threaded connection includes a steel pipe 
20m, a steel pipe 20f, and a coupling 50 for connecting the steel pipes 20m 
and 20f. The pipe bodies 21m and 21f of the steel pipes 20m and 20f include 
annular marking grooves 23m and 23f, respectively, formed on the outer 
peripheries of the pipe bodies 21m and 21f.
Patent AU-2023202338-A1 (AU)
Title: Glycoengineering of E-selectin ligands
Inventor: SACKSTEIN ROBERT
IPC: C12N5/077
Filed: 2023-04-17
Abstract: The present invention provides methods of enforcing expression of an E-selectin 
and/or L-selectin ligand on a surface of a cell. Also provided are methods of 
enabling and/or increasing binding of a cell to E-selectin and/or L-selectin, methods 
of increasing homing and/or extravasation in a population of transplanted cells, 
methods of producing modified cells, including stem cells, for transplanting into a 
subject, methods of treating or ameliorating the effects of a symptom, a disease or 
an injury in a subject, and methods for inducing and/or enhancing homing of a 
population of cells to a therapeutic target in a subject. The invention further 
provides pharmaceutical compositions comprising a population of cells produced by 
the methods of the invention and kits that include such compositions for treating or 
ameliorating the effects of a symptom, a disease or an injury in a subject.
Patent AU-2023202746-A1 (AU)
Title: Combination of a BCL-2 inhibitor and a MCL-1 inhibitor, uses and pharmaceutical compositions thereof
Inventor: WEI ANDREW
IPC: A61K31/4353
Filed: 2023-05-03
Abstract: COMBINATION OF A BCL-2 INHIBITOR AND A MCL-1 INHIBITOR, 
USES AND PHARMACEUTICAL COMPOSITIONS THEREOF 
ABSTRACT 
A combination comprising a BCL-2 inhibitor and a MCL1 inhibitor, and compositions and uses 
thereof.
Patent AU-2023210594-A1 (AU)
Title: Solid forms of a toll-like receptor modulator
Inventor: ASSELIN SYLVIE M
IPC: C07D471/04
Filed: 2023-08-02
Abstract: SOLID FORMS OF A TOLL-LIKE RECEPTOR MODULATOR 
ABSTRACT 
The present disclosure provides solid forms, solvates and hydrates of (R)-2-((2-amino-7
fluoropyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan--ol, and methods ofmaking.
Patent AU-2023248163-A1 (AU)
Title: Top cover, base for child safety seat and child safety seat
Inventor: ZENG XIANGYONG
IPC: B60N2/26
Filed: 2023-10-13
Abstract: TOP COVER, BASE FOR CHILD SAFETY SEAT AND CHILD SAFETY SEAT 
ABSTRACT 
This disclosure provides a top cover for a base, a base for a child safety seat and a child 
safety seat, wherein the top cover comprises a top cover body, an upper surface of the top 
cover body is provided with a protrusion located at a front end of the top cover body, and the 
upper surface of the top cover body is further provided with a seat area located on a periphery 
of the protrusion for a child to sit. In the top cover this disclosure, a protrusion is provided 
on the upper surface of top cover body of the top cover, a protrusion can block a forward 
movement of a child sitting in the seat area when an accidental impact occurs, reducing a 
pressure on the child's abdomen due to the accidental impact, and making the child sitting on 
the top cover safer.  
(Fig. 2)
2/2 
100 
13 12 
11 
Fig. 2
Patent AU-2024200273-A1 (AU)
Title: Pharmaceutical compositions for the treatment of cftr mediated diseases
Inventor: VERWIJS MARINUS JACOBUS
IPC: A61K9/20
Filed: 2024-01-16
Abstract: [00463] Pharmaceutical compositions comprising 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5
yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1) in Form I and a 
solid dispersion comprising substantially amorphous N-(5-hydroxy-2,4-ditert-butyl-phenyl)-4
oxo-1H-quinoline-3-carboxamide (Compound 2), methods of treating, lessening the severity of, 
or symptomatically treating CFTR mediated diseases, such as cystic fibrosis, methods of 
manufacturing, methods of administering, and kits thereof are disclosed.  
145
Patent WO-2009018630-A1 (WO)
Title: Sangle améliorée permettant de fixer un snowboard ou autre et fixation obtenue à l'aide d'une telle sangle
IPC: A63C10/06
Filed: 2008-07-24
Abstract: La présente invention concerne une sangle améliorée permettant de fixer un snowboard, ou analogue. L'invention se caractérise : en ce que la sangle (1) est formée d'au moins une courroie souple (2, 3) qui peut se fixer sur la chaussure (15) d'un utilisateur; en ce que cette sangle (1) comprend également des éléments à pression (4 et 5) qui fonctionnent respectivement avec les courroies (2, 3) précitées; et en ce que celles-ci laissent la partie centrale du pied exempte de toute pression lors de l'utilisation de la sangle.
Patent WO-2017136905-A1 (WO)
Title: Charge à fragmentation à éléments de destruction prêts à l'emploi
Inventor: PETKOV STANCHO PETKOV
IPC: F42B12/32
Filed: 2016-10-28
Abstract: L'invention concerne une charge à fragmentation à éléments de destruction cinétiques prêts à l'emploi, visant à détruire des moyens humains et d'artillerie ennemis se trouvant en extérieur dans des tranchées et des étendues de champs au moyen d'une propagation radiale du flux des éléments de destruction cinétiques prêts à l'emploi. La charge à fragmentation est constituée d'une douille complexe de calibre de recouvrement (2) sur un calibre 4 и à l'intérieur de laquelle est logé un explosif de charges militaires à fragmentation-minage (8). Le dispositif d'amorce avant (1) se trouve dans la partie avant, tandis que les éléments de destruction cinétiques prêts à l'emploi (7) sont technologiquement montés sous forme d'ensemble dans la partie cylindrique des douilles. La charge de départ de poudre noire (5) avec stabilisant est solidement montée à l'arrière de la charge militaire de calibre (4).