baber/WOPTO huggingface dataset:
Patent CA-3099729-A1 (CA)
Title: Methods of examining host-biome interactions using an intestine-on-a-chip
Inventor: KERNS S
IPC: C12M1/06
Filed: 2019-05-09
Abstract: The present invention relates to a combination of microbes, cell culture systems and microfluidic fluidic systems for use in providing a human Intestine On-Chip with optimal intestinal motility. More specifically, in some embodiments, a microfluidic chip containing intestinal epithelial cells co-cuitured with intestinal endothelial cells in the presence of bacteria, such as probiotic bacteria, may find use in providing an Intestine- On-Chip for testing intestinal motility function. In some embodiments, an Intestine On- Chip may be used for identifying (testing) therapeutic compounds continuing probiotic microbes or compounds for inducing intestinal motility' for use in treating gastrointestinal disorders or diseases related to intestinal function.
Patent CA-3100386-A1 (CA)
Inventor: CAMPANA DARIO
IPC: C07K16/28
Filed: 2019-05-23
Abstract: The present invention provides engineered immune cells comprising an anti-CD2 protein expression blocker (PEBL) and an anti-CD2 chimeric antigen receptor (CAR). In some embodiments, such engineered immune cells lack surface expression CD2. Also, provided herein are methods of using such cells in cancer therapies.
Patent CA-3101173-A1 (CA)
Title: Souche de lactobacillus crispatus kbl693 et utilisation associee
Inventor: KO WOO RI
IPC: A61P27/14
Filed: 2019-05-23
Abstract: La présente invention concerne une souche de Lactobacillus crispatus KBL693 et une utilisation associée. La souche de Lactobacillus crispatus KBL693 (numéro d'enregistrement KCTC 13519BP) selon la présente invention atténue les réponses allergiques des cellules et fait régresser significativement les symptômes de la dermatite atopique, avec la présentation concomitante d'effets anti-inflammatoires et anti-fongiques. Ainsi, la souche unique peut atteindre seule tous les objectifs d'atténuation de la dermatite atopique et d'autres maladies allergiques, maladies inflammatoires et maladies auto-immunes, trouvant ainsi des applications avantageuses en tant que substance probiotique. De plus, sur la base de son activité anti-fongique, la souche peut être avantageusement utilisée dans un agent topique cutané contre diverses maladies de la peau provoquées par des champignons et dans une composition cosmétique et un patch fonctionnel pour soulager la peau sensible.
Patent CA-3101718-A1 (CA)
Title: Method and system for determining the separation distance between a bodyand the surface of an object by means of low coherence optical interferoometry techniques under distortion due to sub-sampling
Inventor: DONADELLO SIMONE
IPC: B23K26/02
Filed: 2020-12-04
Abstract: ABSTRACT  A method and a system are described for determining the separation distance between an object or a material and a processing tool or an instrument for measuring the object or material, comprising: -    generating a measurement low coherence optical radiation beam, leading the measurement beam towards the object and leading the reflected or diffused measurement beam from the object towards an optical interferometric sensor arrangement in a first direction of incidence, ¨ generating a reference low coherence optical radiation beam, and leading the reference beam towards the optical interferometric sensor means in a second direction of incidence at a preset angle of incidence with respect to the first direction of incidence of the measurement beam; -    superimposing the measurement beam and the reference beam on a common region of incidence of the sensor means; -    detecting the position of a pattern of interference fringes between the measurement beam and the reference beam on the region of incidence; and -    determining a difference in optical length between the measurement optical path and the reference optical path on the basis of the position of the pattern of interference fringes along an illumination axis of the region of incidence, which is indicative of a difference between (a) the current separation distance between the processing tool or measuring instrument and the surface of the object and (b) the predetermined nominal separation distance, wherein the sensor means comprise an arrangement of photodetectors along the illumination axis, and the angle of incidence is controlled in such a way that the spatial frequency of the pattern of interference fringes is greater than the spatial frequency of the photodetectors. (Fig. 3) Date Recue/Date Received 2020-12-04
Patent CA-3103955-A1 (CA)
Inventor: SHIMIZU TATSUNORI
IPC: F16H57/029
Filed: 2019-06-25
Abstract: An electric actuator 1 is provided with a drive section 2, a drive force transmitting mechanism 3, a motion converting mechanism 4, a housing space which houses the drive section 2, the drive force transmitting mechanism 3, and the motion converting mechanism 4, and a vent section 5. The vent section 5 is provided with a vent hole 53 which extends through a partition wall for defining the drive force transmitting mechanism 3, an air flow passage 46 which communicates with the vent hole 53, and a filter 60.
Patent CA-3105421-A1 (CA)
Inventor: HUGGINS TERENCE
IPC: A47B96/00
Filed: 2021-01-08
Abstract: A cabinet comprised of side panel members, a top panel member and a bottom panel member wherein the cabinet is configured to be releasably secured so as to be shipped in a disassembled state. The cabinet further includes a back panel member that will operably couple with all other panel members of the cabinet.  The back panel member includes a dadoed rabbet edge along both of the lateral edges and both of the longitudinal edges. The formation of the edges of the back panel member facilitate a securing to the two side panel members, the tope panel member and the bottom panel member so as to provide greater structural integrity of the cabinet and improved load bearing. The panel members of the cabinet include grooves formed on inner surfaces thereof and further have locking mechanisms and locking receptacles that are configured to provide assembly of the cabinet.
Patent CA-3105838-A1 (CA)
Title: Sheet having removable labels and related method
Inventor: HONG LE-HOA
IPC: C09J7/40
Filed: 2009-04-23
Abstract: A label sheet including a facestock haying a first label that is adjacent to a second label and a liner releasably adhered to the facestock and haying a first weakened separation line and a second weakened separation line, with each of the weakened separation lines haying opposing ends. One of the opposing ends of the first weakened separation line intersects one of the opposing ends of the second weakened separation line. The other of the opposing ends of the first weakened separation line intersects the other of the opposing ends of the second weakened separation line. The first weakened separation line at least partially underlies a portion of the first label and the second weakened separation line at least partially underlies a portion of the second label. The liner is configured to be separated along the first weakened separation line and separation of the liner along the first weakened separation line results in the first label being partially separated from the liner.
Patent CA-3106161-A1 (CA)
Inventor: HALE ROBERT G
IPC: A61C8/00
Filed: 2019-07-09
Abstract: The present disclosure relates to single tooth or full arch dental restoration. In cases where patients have insufficient bone stock for conventional root-form dental implants, current solutions often fail to restore function. The present disclosure describes a transalveolar dental implant for single tooth or full arch dental restoration. The transalveolar dental implant is comprised of a post and a bone plate, the bone plate having a contoured portion fabricated to match the topography of a bony surface of the facial skeleton. Through primary fixation of the contoured portion of the bone plate, the transalveolar dental implant improves function and outcomes in affected patients.
Patent CA-3107948-A1 (CA)
Title: Transcription factor profiling
Inventor: ULZ PETER
IPC: G06N5/04
Filed: 2019-10-08
Abstract: Methods and systems disclosed herein can improve analysis capabilities of genomic materials. The methods provided herein may examine transcription factor binding site accessibility to diagnose a disease or monitor progression of a disease in a subject.
Patent CA-3107968-A1 (CA)
Title: A power tool
Inventor: MOK KWOK TING
IPC: B23D67/08
Filed: 2018-07-30
Abstract: A power tool (100) comprising a generally elongate tool housing (210) defining a longitudinal axis parallel with the length of the tool housing (210), a work tip (250) located at a first end of the tool housing (210) for supporting a work member (260), and a power source interface (240) located at a second end of the tool housing (210) for supporting a removable power source. The tool housing (210) comprising an elongate handle-shaped grip region (230) between the work tip (250) and the power source interface (240), and generally parallel to the longitudinal axis, and a drive region (220) that substantially encloses a motor (270) separately from the handle-shaped grip region (230), and wherein the motor (270) is located between the handle-shaped grip region (230) and the work tip (250). A housing (210) for a power tool (100) comprising an elongate drive region (220) defining a longitudinal axis having a first girth configured to substantially enclose a tool motor (270) and transmission (280), and an elongate handle-shaped grip region (230) generally coupled with the drive region (220) and parallel to the longitudinal axis having a second girth configured to conform to an ergonomic profile of a user's hand, wherein the second girth is smaller than the first girth.
Patent CA-3108885-A1 (CA)
Inventor: GOJO SATOSHI
IPC: A61K35/28
Filed: 2019-08-13
Abstract: The present invention provides methods and compositions for generation of mitochondria replaced cells (MirC), and therapeutic methods for using such compositions for treating a subject having an age-related disease or syndrome, mitochondrial disease or disorder, or otherwise in need of mitochondrial replacement. Also provided are methods and compositions for producing a recipient cell having a mitochondrial disease or disorder, as well as methods and compositions for producing or enhancing production of an inducible pluripotent stem cell (iPSC). in addition, methods and compositions to enhance mitochondrial transfer are also included.
Patent CA-3109234-A1 (CA)
Inventor: DOUGLAS DAVID BYRON
IPC: G06F3/00
Filed: 2019-08-23
Abstract: L'invention concerne des outils virtuels utilisés pour manipuler des aspects d'un volume d'image médicale en trois dimensions. Les outils virtuels sont géo-enregistrés avec le volume d'image. La présentation du volume d'image est manipulée par un processeur d'image en réponse à l'utilisation des outils virtuels. Les outils virtuels peuvent être utilisés pour faciliter l'analyse du volume d'image. Les outils virtuels peuvent comprendre : un stylo à point focal virtuel ; un curseur 3D virtuel ; un visualiseur de transport virtuel ; un socle virtuel ; un couteau virtuel ; un cathéter virtuel ; un panneau de signalisation virtuel ; un outil d'ablation virtuel ; une table virtuelle ; un outil de contraste virtuel ; et des icônes virtuelles.
Patent CA-3110773-A1 (CA)
Inventor: TZACHEV CHRISTO TZACHEV
IPC: A61K47/38
Filed: 2018-09-11
Abstract: The invention relates to mucoadhesive dispersion nanoparticle system applicable in pharmacy, medicine and cosmetics, especially by administration to surfaces with intensive physiological clearance such as nasal, pulmonal, ocular, oral, throat, rectal, vaginal etc. surfaces, as well as to the method for production such mucoadhesive dispersion nanoparticle system. The composition of mucoadhesive dispersion nanoparticle system comprising in an aqueous medium 0.01 to 2.00 w % hydroxypropyl methyl cellulose and from 0,10 to 10 w% dispersed solid lipid nanoparticles (SLN) for intracellular release of active substances. The advantages of the composition of SLN mucoadhesive dispersion nanoparticle system of the invention are an increased efficacy and controllable depo-effect for transport and delivery of active substances, forming of a continuous film over the applied epithelial surface and substantially increasing of the retention time of the applied dose.
Patent CA-3111086-A1 (CA)
Title: Insecticidal proteins and methods for their use
Inventor: CERF DAVID CHARLES
IPC: C07K14/415
Filed: 2019-10-09
Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
Patent CA-3111647-A1 (CA)
Inventor: TSAI GUOCHUAN EMIL
IPC: A61K31/42
Filed: 2019-09-12
Abstract: Selon l'invention, une forme posologique solide comprend un noyau interne contenant un composé cyclosérine et une couche externe fixée au noyau interne. La forme posologique peut être un comprimé entérique ou un timbre transdermique, approprié pour le traitement d'un trouble neuropsychiatrique ou de la tuberculose.
Patent CA-3113459-A1 (CA)
Inventor: WAN LIRONG
IPC: F15B1/24
Filed: 2019-12-24
Abstract: A high-capacity bladder type constant pressure accumulator and an application thereof. The accumulator comprises a housing (1), as well as a bladder (2), a variable-area piston (4), a floating piston (5), a piston (8) and a flange (11) provided in the housing (1). The floating piston (5) is sleeved on a piston rod of the variable-area piston (4). The bottom of the piston rod of the variable-area piston (4) is connected to the piston (8), and a through hole is formed along the center axes of the variable-area piston (4) and the piston (8). An inflation valve (3) is connected between the through hole and the bladder (2). A cover plate (10) is connected to the bottom of the through hole. A check valve I (6) and a check valve II (7) are provided on the piston (8). The flange (11) is connected to the inner wall of the bottom of the housing (1). This accumulator has the advantages of high oil storage capacity and constant pressure during energy release.
Patent CA-3113494-A1 (CA)
Inventor: DANG TRANH VI
IPC: H04W4/30
Filed: 2021-03-30
Abstract: A system and method are provided for parking lot management. The method includes detecting entry of a vehicle into a parking lot, by capturing an image thereof, identifying a mobile application corresponding to the vehicle, detemining an occupancy status of the parking lot by monitoring a parking area of the parking lot using a camera and sending the occupancy status to the mobile application. The method further includes detecting exit of the vehicle from the lot by capturing an image of the vehicle at the exit by a camera, identifying the vehicle on the captured image, determining a parking duration of the vehicle in the parking lot based on an entry time of the vehicle into the parking lot and an exit time of the vehicle from the parking lot, and sending a second message including the parking duration to the mobile application or to a cloud server.
Patent CA-3114003-A1 (CA)
Title: Flow rate optimization during simultaneous multi-well stimulation treatments
Inventor: HUNTER TIMOTHY HOLIMAN
IPC: E21B47/06
Filed: 2018-12-21
Abstract: System and methods of controlling fracture growth during multi-well stimulation treatments. The flow distribution of treatment fluid injected into first and second well formation entry points along multiple wellbores is monitored during a current stage of a multi-well, multistage stimulation treatment. Upon determining the fracture growth and/or monitored 5 flow distribution meets a threshold, a remainder of the current stage is partitioned into a plurality of treatment cycles and at least one diversion phase. A portion of the fluid to be injected into the first well and/or second well formation entry points is allocated to each of the treatment cycles of the partitioned stage. The treatment cycles are performed for the remainder of the current stage using the treatment fluid allocated to each treatment cycle, wherein the flow distribution is adjusted so as not to meet the threshold.
Patent CA-3116490-A1 (CA)
Title: A simulated blood vessel for use in a trauma simulator
Inventor: PALLISTER IAN
IPC: G09B23/30
Filed: 2019-09-13
Abstract: The present invention relates to a simulated blood vessel for use in a trauma simulator. The simulated blood vessel comprises a flexible, resilient body and has a fluid channel integrally moulded within the body. The fluid channel has first and second ends and a compression zone located lengthwise between the first and second ends that is compressible between an open configuration and a closed configuration in which flow through the fluid channel is blocked. The compression zone has a compression axis arranged transverse to the length of the fluid channel along which a compression force is applied to the fluid channel in use, and the compression zone has a cross sectional shape having a first axis aligned with the compression axis and a second axis arranged transverse to the first axis, and the diameter of the fluid channel along the second axis is greater than diameter along the first axis to enable the fluid channel to be more easily compressed to the closed configuration.
Patent CA-3116671-A1 (CA)
Inventor: KOMSA JAMES
IPC: A61B18/14
Filed: 2019-10-15
Abstract: L'invention concerne un ensemble adaptateur pour fixer un dispositif d'éclairage à un instrument chirurgical portatif, qui comprend une première partie corps configurée pour venir en prise avec une partie extrémité distale de l'instrument chirurgical à une position le long d'un axe central de celui-ci, et une seconde partie corps configurée pour supporter un dispositif d'éclairage adjacent à la partie extrémité distale de l'instrument chirurgical, de telle sorte qu'un axe d'éclairage du dispositif d'éclairage coupe angulairement l'axe central de l'instrument chirurgical.
Patent CA-3116978-A1 (CA)
Inventor: OLAH MICHAEL G
IPC: C08G63/91
Filed: 2019-10-17
Abstract: There is described a method for the production of a functional polyester having functional group X. The method comprises the step of melt blending a composition comprising (i) a high number average molecular weight (Mn) polyester having a Mn of =6,000 Da; and (ii) a functional compound comprising functional group Y which may be the same as functional group X or be different to functional group X but be operable to form functional group X in the functional polyester. The composition is melt blended such that the high Mn polyester and the functional compound react to produce the functional polyester. The high Mn polyester has a Mn that is higher than the Mn of the functional compound. The present invention extends to functional polyesters produced by the method; aqueous, solventborne and powder coating compositions containing the functional polyester; and articles coated with the said coating compositions.
Patent CA-3118192-A1 (CA)
Title: Tiled floor assembly and components
Inventor: ALLEN WARWICK JAMES
IPC: E04F15/024
Filed: 2019-10-31
Abstract: A suspended timber frame deck comprising a timber frame of interconnected timber beams. Tiles are located on top of the beams indirectly at at least two locations by a tile support pad located between the tile and an underlying timber beam. Each pad includes a protrusion located in a hole of the timber beam to register therewith to the timber beam and registered to the tile to help locate the tile to the timber beam and help prevent the tile from sliding over the timber beam.
Patent CA-3121173-A1 (CA)
Title: Logic circuitry package
Inventor: GARDNER JAMES MICHAEL
IPC: G06F21/44
Filed: 2019-12-03
Abstract: A logic circuitry package includes an interface to communicate with a print apparatus logic circuit and at least one logic circuit. The logic circuit is configured to receive, via the interface, a plurality of first requests in a heater disabled mode, each first request corresponding to a different sensor ID of a plurality of sensor IDs; transmit, via the interface, a first digital value in response to each first request; receive, via the interface, a plurality of second requests in a heater enabled mode, each second request corresponding to a different sensor ID of the plurality of sensor IDs; and transmit, via the interface, a second digital value in response to each second request. Delta values corresponding to a difference between the first digital value and the second digital value for each different sensor ID of the plurality of sensor IDs are indicative of a print material level.
Patent CA-3122428-A1 (CA)
Title: Transmembrane domain derived from human lrrc24 protein
Inventor: KIM SEONG JUN
IPC: A61K38/08
Filed: 2019-12-16
Abstract: The present invention relates to a transmembrane domain derived from human LRRC24 protein. More specifically, the present invention relates to a transmembrane domain derived from the human LRRC24 protein (LRRC24P transmembrane domain) or a cell-penetrating peptide, and an intracellular delivery system comprising same. The transmembrane domain derived from the human LRRC24 protein of the present invention can be used to deliver cargo materials such as compounds, biomolecules, and various polymer materials into cells. Since the LRRC24P transmembrane domain of the present invention exhibits higher cell penetration efficiency compared to conventional cell-penetrating peptides and is derived from human proteins, thus avoiding side effects and immune responses caused by peptides derived from foreign proteins, it can be usefully used as an effective intracellular delivery method for compounds, biomolecules, and various polymer materials applied to the human body.
Patent CA-3123364-A1 (CA)
Title: Oil and fat composition for heat cooking
Inventor: NISHIMURA SAKI
IPC: A23D9/00
Filed: 2019-12-10
Abstract: Provided are: a fat composition for cooking that achieves excellent suppression of the negative aspects of cooking with edible fat; and an edible ingredient for the fat composition for cooking. A fat composition for cooking that includes: an n-3 edible fat in which n-3 fatty acids are 3080 mass% of total fatty acids; and a base fat that comprises an edible fat other than the n-3 edible fat. The fat composition is characterized by containing at least 0.01 mass% but less than 1 mass% of the n-3 edible fat.