Patent SG-11201901273T-A (SG)
Title: Blood plasma fractions as a treatment for aging-associated cognitive disorders
Inventor: NIKOLICH KAROLY
IPC: A61K38/38
Filed: 2017-04-27
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization 11111111111101110101011111011111010 011111101111110 II 0111011111110 MI MIE International Bureau (10) International Publication Number (43) International Publication Date .....0\"\"\"1 WO 2018/034712 Al 22 February 2018 (22.02.2018) WIP0 I PCT (51) International Patent Classification: MCCRACKEN, Joe [US/US]; 632 Fairway Circle, Hills- A61K 38/38 (2006.01) A61K 35/14 (2006.01) borough, California 94010 (US). NIKOLICH, Karoly (21) International Application Number: [US/US]; 624 Lakemead Way, Emerald Hills, California PCT/US2017/029953 94062 (US). (22) International Filing Date: 27 April 2017 (27.04.2017) (74) Agent: FIELD, Bret, E.; 201 Redwood Shores Parkway, Suite 200, Redwood City, California 94065 (US). (25) Filing Language: English (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, (26) Publication Language: English AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (30) Priority Data: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, 62/376,529 18 August 2016 (18.08.2016) US DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, 62/412,258 24 October 2016 (24.10.2016) US HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, (71) Applicant: ALKAHEST, INC. [US/US]; 75 Shoreway MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, Road, Suite D, San Carlos, California 94070 (US). PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, (72) Inventors; and TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (71) Applicants: BELL, David [US/IE]; Grange Castle Busi- ness Park, Clondalkin, Dublin, 22 (IE). GALLAGER, Ian (84) Designated States (unless otherwise indicated, for every [US/US]; 354 Avenue Granada, Half Moon Bay, Califor- kind of regional protection available): ARIPO (BW, GH, nia 94019 (US). BRAITHWAITE, Steven P. [GB/US]; GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, 505 Jetty Way, Redwood City, California 94065 (US). MI- UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, = NAMI, S. Sakura [US/US]; 230 Dolores St., #105, San Francisco, California 94103 (US). DANG, Vu [US/US]; TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, = 215 N Kingston St., San Mateo, California 94401 (US). MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, — = (54) Title: BLOOD PLASMA FRACTIONS AS A TREATMENT FOR AGING-ASSOCIATED COGNITIVE DISORDERS = (57) : Methods and compositions for treating and/or preventing ag- ing-related conditions are described. The compositions used in the methods in- Figure 5 dude fractions derived from blood plasma with efficacy in treating and/or pre- - venting aging-related conditions such as neurocognitive disorders. 4 = = = = = = _ _ = 1-1 ei 1-1 IN ii- en SAL SAL PPF1 HA : f : 0 • -.... 00 ,-1 0 0 0 ei C [Continued on next page] WO 2018/034712 Al MIDEDIMOMMIDIIMERINIMIIMIMBOHOIREM TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))