baber/WOPTO huggingface dataset:
Patent CA-2306748-A1 (CA)
Title: Treatment of fibromyalgia and related disorders
Inventor: ANDRUS G MERRILL
IPC: A61K33/06
Filed: 1998-10-07
Abstract: A method of treating fibromyalgia-like complaints (i.e., fibromyalgia, chronic fatigue syndrome and irritable bowel syndrome) in a patient, the method comprising: administering to the patient an 1H-indole-3-methanol compound (e.g., 1H-indole-3-methanol, ascorbigen, bis(3-indolyl) methane, indolo[3,2-b(carbozole)], 2-(indol-3-ylmethyl)-3,3'-diindolylmethane, 5,6,11,12,17,18-hexahydro-cyclonona[1,2-b; 4,5-b'; 7,8-b"]triindole, 1H-indol-3-yl methoxy methane, ethoxy 1H-indol-3-yl ethoxy methane, other ethers of 1H-indole-3-methanol) in a medically acceptable manner in a pharmaceutically effective amount on a regular basis. It has been found that the administration of such indoles, particularly 1H-indole-3-methanol, greatly mitigates the most severe symptoms of fibromyalgia.  Patients with fibromyalgia have reported a decrease in pain, less fatigue, improved sleep patterns, and an improved sense of well being resulting from the oral administration of pharamceutically effective amounts of an 1H-indole-3-methanol compound each day.
Patent CA-2309310-A1 (CA)
Title: Fittings and process for producing fittings for the mechanical processing of aqueous paper stock
Inventor: SCHNEID JOSEF
IPC: D21D1/30
Filed: 2000-05-24
Abstract: A process for producing a fitting for the mechanical processing of aqueous fiber stock and a fitting made by the process. The fitting includes at least one base body and at least one processing element. The process includes producing at least one hard material body which forms at least a portion of the at least one processing element, and penetrating the at least one hard material body with a binder and permanently bonding the at least one hard material body and the binder.
Patent CA-2309388-A1 (CA)
Inventor: HURNAUS RUDOLF
IPC: A23K1/16
Filed: 1998-12-08
Abstract: La présente invention concerne des uréthanes dérivés d'azacycloalcanes, ainsi que leurs analogues thio et dithio, correspondant à la formule générale (I), dans laquelle: m représente le nombre 0 ou 1; n représente le nombre 1 ou 2; A représente une liaison simple, un groupe alkylène C¿1-8?, un groupe alcénylène C¿2-8? ou un groupe alkinylène C¿2-8?, un groupe insaturé n'étant pas lié directement au resteY; X et Y représentent un atome d'oxygène ou de soufre; R?1¿ et R?2¿ représentent un groupe alkyle C¿1-6? à chaîne droite ou ramifiée, un groupe alcényle C¿1-4? ou un groupe alkinyle C¿1-4?, une liaison multiple étant isolée de la liaison azote-carbone, ou bien R?1¿ et R?2¿ représentent avec l'atome d'azote un noyau hétérocyclique saturé possédant 5 à 7 éléments, dans lequel un groupe méthylène isolé de l'atome d'azote peut être remplacé par un atome d'oxygène ou de soufre ou par un groupe -NH- ou -N(alkyle); R?3¿ à R?6¿ peuvent être identiques ou différents et représentent des atomes d'hydrogène ou des groupes alkyle; R?7¿ représente un groupe cycloalkyle C¿3-7?, un groupe phényle ou naphtyle éventuellement substitué par un ou deux atomes d'halogène ou par un groupe alkyle, alcoxy, trifluorométhyle ou cyano, ou bien représente également un atome d'hydrogène, à condition que A ne représente pas une liaison simple; E représente un atome d'oxygène ou de soufre, un groupe méthylène, carbonyle ou sulfinyle; et R?8¿ représente un atome d'hydrogène ou bien E représente le groupe -C(R?9¿R?10¿)- où R?9¿ représente un atome d'hydrogène et R?10¿ représente avec le groupe voisin R?8¿ une liaison carbone-carbone. La présente invention concerne en outre les énantiomères, les diastéréomères et les sels desdits dérivés, en particulier les sels d'addition d'acide physiologiquement compatibles, qui présentent des caractéristiques précieuses, en particulier un effet inhibiteur vis-à-vis de la biosynthèse du cholestérol. L'invention concerne également des médicaments contenant ces composés, leur utilisation et leur procédé de production.
Patent CA-2312973-A1 (CA)
Inventor: CALHOUN HERBERT NEWTON
IPC: H04W4/12
Filed: 1998-12-03
Abstract: L'invention porte sur la transmission de messages courts à l'intérieur d'un système de télécommunications (100) se déroulant de la manière suivante: une station de base (101) d'un tel système (100) constate que la transmission d'un message court à destination d'une unité éloignée (113) doit avoir lieu. La station de base (101) détermine alors un circuit si de canal de messagerie (107) est disponible. La station de base (101) détermine en particulier si le circuit de canal de messagerie (107) est chargé au-delà d'un certain seuil. Si c'est le cas, et si l'unité éloignée (113) n'utilise pas de canal de trafic, la station de base (101) transmet le message court à l'unité éloignée (113) via le canal de trafic. Par ailleurs, la transmission à l'unité éloignée (113) via le canal de trafic se fait sans préavis ( c.-à-d. qu'une personne utilisant l'unité éloignée (113) ne sera pas avertie que la transmission sur le canal de trafic à lieu).
Patent CA-2314326-A1 (CA)
Title: Transdermal therapeutic device and method with capsaicin and capsaicin analogs
Inventor: ROBBINS WENDYE R
IPC: A61K31/445
Filed: 1998-12-08
Abstract: Transdermal application of capsaicin (or a capsaicin analog) in a concentration from greater than about 5 % to about 10 % by weight has been discovered to be an extremely effective therapy for treating neuropathic pain, so long as an anesthetic, preferably by means of a transdermal patch, is administered initially to the affected area to minimize the expected side effects from subsequent capsaicin application.
Patent CA-2315545-A1 (CA)
Title: Process for manufacturing composite material primary structures with female tool curing
Inventor: CEREZO PANCORBO CARLOS
IPC: B29C70/44
Filed: 2000-08-08
Abstract: A process for manufacturing primary structures of composite material with female tool curing, comprising the lamination of superimposed. composite material layers in a pre-impregnated state; placing the obtained laminate over a forming tool, loading the assembly in a vacuum bell and applying a pre-established forming cycle; loading the already formed, but still in a green state, laminate in a female tool (4) suitable for its curing, placing lateral beetles (5) and inserting elastomeric pipes (6) in channels of said beetles, fitting a central beetle (5), sealing the assembly and making a vacuum bag with perforations to remove the air from inside; and loading the assembly in an autoclave, then hermetically closing the autoclave and carrying out the corresponding curing cycle. The invention is applicable to the field of aeronautics.
Patent CA-2316859-A1 (CA)
Title: Spring rate balancing of the flow tube and a balance bar in a straight tube coriolis flowmeter
Inventor: VAN CLEVE CRAIG BRAINERD
IPC: G01F1/84
Filed: 1999-02-05
Abstract: A Coriolis flowmeter having a single straight flow tube, a balance bar parallel to said flow tube, a brace bar connecting ends of the balance bar to the flow tube and to a surrounding case. Improved dynamic balance of the flowmeter is maintained in response to changes in density of the flowing material by reducing the spring function of the balance bar and/or the flow tube. This concentrates the spring function of the flowmeter in the brace bar structure. A vibrational node in the brace bar structure separates the effective spring function of the balance bar from the effective spring function of the flow tube. The vibrational node moves within the brace bar in response to materials of different densities in the flow tube at different times. This nodal movement changes the ratio of the effective balance bar spring function to that of the effective flow tube spring function to maintain improved dynamic vibrational balance of the flowmeter without involving the case mass.
Patent CA-2318611-A1 (CA)
Title: Process for increasing the melt strength of polypropylene
Inventor: PEETERS GARY
IPC: C08L23/26
Filed: 1999-01-19
Abstract: A process for modifying a polypropylene (co)polymer wherein said process comprises melt mixing the polypropylene (co)polymer in the presence of an initiator wherein said initiator is selected from the group defined by formula (1), wherein R is selected from the group consisting of optionally substituted C1 to C18 acyl, optionally substituted C1 to C18 alkyl, aroyl defined by formula (2), and compounds of formula (3), wherein U, V, X, Y, Z, U', V', X', Y' and Z' are independently selected from the group consisting hydrogen; halogen; C1-C18 alkyl; C1-C18 alkoxy, aryloxy, acyl, acyloxy, aryl, carboxy, alkoxycarbonyl, aryloxycarbonyl, trialkyl silyl, hydroxy, or a moiety of formula (4), and wherein T is alkylene.
Patent CA-2318662-A1 (CA)
Title: Procede de determination de la fonction de sequences nucleotidiques et les proteines pour lesquelles elles codent par transfection de telles sequences dans un hote
Inventor: PADGETT HAL S
IPC: C12Q1/68
Filed: 1999-01-15
Abstract: La présente invention concerne des procédés de détermination rapide de la fonction de séquences d'acides nucléiques qui consiste en la transfection desdites séquences dans un organisme hôte afin d'y effectuer une expression; ensuite à analyser les changements phénotypiques et biochimiques ainsi produits afin de déterminer la fonction des acides nucléiques transfectés dans l'organisme hôte. L'invention concerne aussi des procédés de blocage des gènes endogènes par la transfection des hôtes ayant des séquences d'acides nucléiques pour en effectuer l'expression. L'invention concerne en outre des procédés de sélection des fonctions désirées des ARN et des protéines au moyen de vecteurs viraux en vue d'exprimer des banques des allèles des séquences d'acides nucléiques. Finalement l'invention concerne des procédés d'inhibition d'une protéase endogène d'une plante hôte.
Patent CA-2319592-A1 (CA)
Title: Method for the stimulation of sperm production and gonadal development in animals
Inventor: KUENZEL WAYNE J
IPC: A61D19/00
Filed: 1999-02-03
Abstract: Disclosed is a method to stimulate or enhance sperm development in males and gonadal development in females by administration of an agent which results in a transiently lowered level of a thyroid hormone such as T3 and increased gonadotropin levels in the blood.
Patent CA-2319851-A1 (CA)
Inventor: BISKUP LAURENT
IPC: B23K103/10
Filed: 2000-09-22
Abstract: L'invention concerne un procédé et une installation de soudage MIG de l'aluminium et de ses alliages, mettant en oeuvre une protection gazeuse de la zone soudée composée d'un flux central de gaz constitué d'argon et/ou d'oxygène, et d'un flux gazeux périphérique constitué d'argon ou d'un mélange d'argon et d'hélium. Le procédé de soudage MIG de l'invention permet de souder efficacement des pièces en aluminium ou en alliages d'aluminium grâce à une amélioration de la pénétration de la soudure et du mouillage du cordon de soudure, c'est-à-dire de l'angle de raccordement du cordon de soudure sur les pièces soudées.
Patent CA-2320716-A1 (CA)
Title: Improvements in tactile indicators for the visually impaired and method of installation thereof
Inventor: MCCUSKEY CELESTINE PATRICK
IPC: E01F9/04
Filed: 1999-12-23
Abstract: There is a tactile indicator for the visually impaired having at least one marker head (22) which in a position of use protrudes above a walkway surface. A flange (23) extends down from the underside of the marker head (22) and is adapted for a close tolerance sliding fit into a channel cut in said walkway surface. There are a plurality of upwardly inclined ribs (25) formed on the flange (23) so that the flange (23) once push fitted into the channel is secured in place without adhesive by outward pressure of the ribs (25) on the sides of the channel.
Patent CA-2323107-A1 (CA)
Inventor: HOLTZMAN DOUGLAS A
IPC: G01N33/566
Filed: 1999-04-08
Abstract: L'invention porte sur de nouveaux polypeptides T129, de nouvelles protéines et molécules d'acide nucléique. L'invention porte non seulement sur des protéines T129 pleine longueur isolées, mais aussi sur des protéines de fusion T129 isolées, des peptides antigéniques et des anticorps anti-T129. L'invention porte en outre sur des molécules d'acide nucléique T129, des vecteurs d'expression de recombinaison contenant une molécule d'acide nucléique de l'invention, des cellules hôtes dans lesquelles ont été introduits les vecteurs d'expression et des animaux transgéniques dans lesquels un gène a été introduit ou coupé. Des procédés de diagnostic, dépistage et thérapeutiques sont également décrits.
Patent CA-2325856-A1 (CA)
Inventor: HARTIKAINEN KARI
IPC: G01N15/08
Filed: 1999-04-01
Abstract: The invention relates to a method and device for measuring gas permeability through a porous membrane-like material, particularly through paper. In the method, a sample (N) is placed tightly against the edges of an open chamber (20), to which a gas connection is created to a source of constant pressure (18, 17), the predetermined pressure difference being used to create a stable flow of gas through the sample, and to measure at least one volume quantity, which is proportional to the gas permeability of the material. The flow of gas is throttled before being led to the chamber (20), which rapidly stabilizes the flow.
Patent CA-2327075-A1 (CA)
Title: Communication connection merge method and node to be used therefor
Inventor: FUJITA NORIHITO
IPC: H04L45/50
Filed: 2000-11-29
Abstract: A communication connection merge method and a node to be employed in the same can merge parameter of LSP, such as request bandwidth or the like, upon performing merging. The communication connection merge method performs merge process for consolidating a plurality of communication connection of a connection-oriented network at a node on the way of transfer route into a common communication connection by making judgment of possibility to have a common transfer route from a node to merge to an egress node upon merging new communication connection on setting for existing communication connection, modifying collateral parameter of the existing communication connection which is judged to merge the new communication connection for enabling accommodation of the new communication connection in the existing communication connection, and performing merge after modification of parameter of the existing communication connection.
Patent CA-2327647-A1 (CA)
Title: Method and system for determining the position of a mobile terminal in a cdma mobile communications system
Inventor: CEDERVALL MATS
IPC: H04B1/707
Filed: 1999-04-06
Abstract: A method and system are disclosed for determining the position of mobile stations (120) in a CDMA cellular system, in which each symbol (S1) to be transmitted by a mobile station (120) is first spread by a short code, and the resulting signal is further spread by a long code. The spreading code (C1) is divided into N-chip sections. Consequently, even if the transmitted symbols are unknown, the N-chip sections of the resulting signal are known (at least to within an unknown phase difference). The mobile station (120) then transmits the resulting spread signal. At the receiving base station, the received spread signal is correlated (and despread) with the known codes, and the original data is reconstructed. As such, the timing of the received signal can be determined with an accuracy of at least the time interval of the unknown phase difference.
Patent CA-2335446-A1 (CA)
Title: Door to doorstep directions
Inventor: HO EDWIN KONG SUN
IPC: G01C21/36
Filed: 1999-05-20
Abstract: An apparatus and method for providing general directions and supplementary information over a network that accesses a database (416) and a map server (414). The map server (414) provides general directions, maps, and geocode information. The database (416) provides supplementary information such as a  name of the building, a place to park, an elevator to take, a certain floor to meet on, and a particular person to meet. Each destination point (412) includes customized supplementary information that provides specific directi on relating to the destination point (412). The supplementary information can b e unique to each particular business. The database (416) can be updated by the  user independent of updates to the map server (414). Combining the map serve r (414) with the database (416) allows a user to obtain specific door to door directions.
Patent CA-2338163-A1 (CA)
Title: Boat or vessel with electric drive
Inventor: BOULY CHRISTIAN
IPC: B63H23/24
Filed: 1999-07-13
Abstract: The invention concerns a boat or vessel with electric drive comprising at least an electric motor mounted in a sealed submersible and adjustable casing (22), the electric motor being of the alternating current type and with high rotating speed and housed in the casing (22) with a power inverter powered by on-board batteries, and a reduction gear for driving a propeller (26) mounted on an output shaft of the casing (22). The invention is particularly useful for electrically driving small or medium sized boats and vessels.
Patent CA-2341544-A1 (CA)
Inventor: KIESSLING ROLF
IPC: A61K39/39
Filed: 1999-08-25
Abstract: L'invention concerne un procédé de vaccination d'un mammifère contre une maladie, comprenant les étapes consistant à administrer à ce mammifère, dans un vecteur approprié, une séquence nucléotidique codant pour un peptide antigénique associé à ladite maladie, à administrer en outre à ce mammifère un composé favorisant les réponses immunes à la fois humorales et cellulaires, amorcées par le peptide antigénique, ce composé étant choisi dans la liste énoncée dans le brevet et étant, de préférence, du Tucaresol, ou le cas échéant, un sel ou ester de celui-ci, acceptable sur le plan physiologique.
Patent CA-2344447-A1 (CA)
Title: Methods and apparatus for authenticating informed consent
Inventor: CLARK ROBERT L
IPC: G09B23/28
Filed: 1999-09-15
Abstract: A method and apparatus for recorded information conveyance and comprehension  are provided that include a Virtual Interactive Teaching and Learning (VITAL ) Center. The VITAL Center provides an interactive patient education and informed consent process that increases patient comprehension using presentations that offer a baseline education about medical and surgical procedures including the associated risks, benefits and alternatives. The patient's comprehension of the material is confirmed throughout the presentation using summary questions focused on key information. The patient  is able to record their own questions or concerns about the procedure while watching the presentation. After the presentation is finished, a healthcare professional reviews the patient questions upon completion of the presentation, and any information the patient did not understand is further explained at this time. After all questions and concerns are addressed and t he patient has a comfortable understanding of the procedure, the patient signs an informed consent electronically. Using digital video capture, the VITAL Cent er simultaneously records the information presented, the patient viewing the interactive presentation, the patient-physician interaction, and the informe d consent process. The entire recorded education session and informed consent is stored permanently on optical disk media.
Patent CA-2344922-A1 (CA)
Inventor: MCCLURE SAMUEL AARON
IPC: F01P7/16
Filed: 2001-04-23
Abstract: A thermostat assembly with a valve mounted to a carrier for installation in an engine thermostat housing. The carrier includes a body portion to which the valve is mounted. A pair of posts extend upward from the body portion and have snap tabs that seat in an annular groove in the thermostat housing. A handle extends from the side posts and includes legs that first project inward from the side posts and then upward to upper distal ends where a cross member connects the legs. The carrier is made of plastic such that when the legs are squeezed together, the side posts deflect to withdraw the snap tabs from the groove to withdraw the snap tabs and enable the carrier to be removed from the housing. The housing also includes an inwardly tapered portion that engages the body portion of the carrier to form a seal therebetween. Fluid pressure when the valve is closed deflects the carrier outward into firm engagement with the conduit.
Patent CA-2349724-A1 (CA)
Title: Silane copolymer coatings
Inventor: TERRY RICHARD N
IPC: C09D183/08
Filed: 1999-11-05
Abstract: The invention is drawn to silane copolymers prepared from the reaction of one or more polyisocyanates with one or more lubricious polymers having at least two functional groups, which may be the same or different, that are reactive with an isocyanate functional group and with one or more organo-functional silanes having at least two functional groups, which may be the same or different, that are reactive with an isocyanate functional group and at least one functional group reactive with a silicone rubber substrate. The silane copolymer coatings of the invention are elastic, lubricious, and resist wet abrasion.  They are useful as coatings for polysiloxane (rubber) and other difficult to coat substrates, especially for medical devices, such catheters.
Patent CA-2350915-A1 (CA)
Inventor: MCCRAE KEITH R
IPC: C12N5/071
Filed: 1999-11-05
Abstract: Two-chain high molecular weight kininogen, and peptide analogs thereof havin g homology to sites within kininogen domain 5, are potent inhibitors of angiogenesis. The peptides have the formula X1-His-Lys-X-Lys-X2 wherein X is  any amino acid, X1 is from zero to twelve amino acids, more preferably from zero to six amino acids, most preferably from zero to three amino acids, and  X2 is from zero to twelve amino acids, more preferably from zero to six amin o acids, most preferably from zero to three amino acids. X is preferably an amino acid having a nonpolar side chain, or a polar side chain which is uncharged at pH 6.0 to 7.0. X is most preferably Asn, Phe or His. Methods of  inhibiting endothelial cell proliferation and angiogenesis are provided.</SD OAB>
Patent CA-2350941-A1 (CA)
Title: Benzamide analogues as parp dna repair enzyme inhibitors
Inventor: GRIFFIN ROGER JOHN
IPC: C07D263/56
Filed: 1995-03-09
Abstract: A range of benzamide analogues consisting of 3-oxybenzamide derivatives are disclosed which can act as potent inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase or PARP enzyme (EC 2.4.2.30), and which thereby can provide useful therapeutic compounds for use in conjunction with DNA-damaging cytotoxic drugs or radiotherapy to potentiate the effects of the latter.      The compounds disclosed include certain benzoxazole-4-carboxamide compounds and in general they comprise compounds having the general structural formula I   (see formula I) or pharmaceutically acceptable salt thereof, characterised in that Y and X together form a bridge -Y-X- that represents the grouping (see formula II) or (see formula III) or (see formula IV) where R5 is H, alkyl or an optionally substituted aralkyl or aryl group.
Patent CA-2353605-A1 (CA)
Inventor: KLAUCK WOLFGANG
IPC: C09J161/00
Filed: 1999-11-30
Abstract: En cas d'utilisation de condensats d'aldéhydes ou de cétones formant du gel avec des polyols dans des cyanacrylates, on obtient des colles, des matières de revêtement et d'étanchéité de stabilité dimensionnelle. Ces produits sont stables au stockage et particulièrement adaptés pour coller des substrats poreux comme le papier ou le bois. Leur manipulation est particulièrement simple lorsque l'on en fait des bâtonnets de colle à frotter.
Patent CA-2356007-A1 (CA)
Inventor: MCLEOD KENNETH LEE
IPC: C10N30/06
Filed: 2001-08-27
Abstract: A method is provided for protecting a copper-containing metal from loss of copper when in contact with a functional fluid composition containing water, the method comprising employing in the functional fluid an oil-soluble dimercaptothiadiazole compound or derivative thereof in an amount sufficient to protect against loss of copper.