baber/WOPTO huggingface dataset:
Patent CA-2676090-A1 (CA)
Inventor: CROTEAU PASCAL
IPC: G16B20/40
Filed: 2008-02-06
Abstract: The present invention relates to the selection of a set of polymorphism markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to ADHD disease and/or their response to a particular drug or drugs.
Patent CA-2680158-A1 (CA)
Title: Alkaliphilic bacillus species .alpha.-amylase variants, compositions comprising .alpha.-amylase variants, and methods of use
Inventor: NAAB COREY
IPC: A23L35/00
Filed: 2008-03-04
Abstract: Disclosed are variants of the alpha-amylase derived from Bacillus sp. no. 707 compositions comprising said variants and methods of using the variants. The methods of use include methods of cleaning surfaces, laundering textiles, desizing, hydrolyzing biofilms off various substrates, and treating starch (e.g., liquefaction and saccharifrication).
Patent CA-2681009-A1 (CA)
Title: Process for preparing ultra-fine sodium bicarbonate powder
Inventor: TINSON ART
IPC: B01D37/00
Filed: 2007-03-26
Abstract: Ultra-fine sodium bicarbonate powder (mean particle size less than 5 microns) is produced by the mixing and reaction under agitation at control temperatures of solutions of ammonium bicarbonate and sodium chloride. Precipitated sodium bicarbonate is separated by filtration as a slurry which is dried to produce ultra-fine sodium bicarbonate. Ultra-fine sodium bicarbonate produced by this method also exhibits a narrow particle size distribution which is advantageous in blowing agents for thermoplastic resins, to produce a foamed resin with small cells of a narrow size distribution.
Patent CA-2681460-A1 (CA)
Title: Electronic stator end winding accelerometer sensor
Inventor: YOUNSI KARIM
IPC: G01M7/02
Filed: 2009-10-01
Abstract: An insulated accelerometer assembly (10) is provided for attachment to a vibrated component (12). A base (16) has a portion for engagement and connection with the vibrated component (12) and to transmit vibration. An accelerometer (34) senses vibration and is located at least partially within the base (16). A  housing (16) at least partially encloses the accelerometer (34) and inhibits voltage discharge, corona damage, and voltage tracking on the accelerometer (34). The housing (16) is made of an insulating material and has an interior for the accelerometer (34).  The housing (16) has a plurality of raised fins (60) on the exterior. A mounting cap (42) also inhibits voltage discharge, corona damage, and voltage tracking and secures the housing (36). The mounting cap (42) is made of insulating material and has an exterior that includes a plurality of raised fins (52). A cable (70) has an electrically conductive wire (82) and has a shield (80) to inhibit electrical noise.
Patent CA-2683053-A1 (CA)
Title: Oligonucleotide compositions for the treatment of alzheimer's disease
Inventor: DE STROOPER BART
IPC: A61K31/7105
Filed: 2008-04-21
Abstract: The invention relates to the identification of microRNAs which expression is diminished in neurodegenerative disorders. In particular, said identified microRNAs can be used for the downregulation of the beta-secretase (BACE1) in mammalian brain and hence for the treatment of Alzheimer's disease.
Patent CA-2683343-A1 (CA)
Title: Email system including an email aggregation server providing polling time gap compacting and related methods
Inventor: KAMAT HARSHAD N
IPC: H04L12/58
Filed: 2007-04-13
Abstract: An electronic mail (email) system may include at least one email server having mailboxes for storing email messages, and a plurality of mobile wireless communications devices. The system may further include at least one email aggregation server for repetitively polling the mailboxes for email messages, and forwarding the email messages to respective mobile wireless communications devices. The at least one email aggregation server may determine time gapped polling of corresponding mailboxes defined by at least one time gap between successive polls, and time compact a subsequent polling of the corresponding mailboxes by removing the at least one time gap.
Patent CA-2686335-A1 (CA)
Inventor: CHANDLER CATHARINA
IPC: A41C3/00
Filed: 2008-04-30
Abstract: A device for placement between a human's breasts for reducing and preventing skin wrinkling in the chest region of a user and a method of supporting the upper positioned breast of a side laying human to reduce and prevent skin wrinkling in the chest region.
Patent CA-2687452-A1 (CA)
Inventor: LO WENLIN
IPC: C22C9/04
Filed: 2009-11-24
Abstract: The present invention provides an environmental friendly brass alloy, including 0.4 to 0.8 wt% of aluminum; 0.6 to 1.6 wt% of nickel; 0.8 to 2.0 wt% of tin; more than 95.6 wt% of copper and zinc; and less than 0.1 wt% of iron, lead, phosphorous and impurities, wherein the copper is present in an amount ranging from 60 to 68 wt%.
Patent CA-2690071-A1 (CA)
Title: Construction with air chambers
Inventor: VON BALLMOOS ROLAND
IPC: B64D11/00
Filed: 2008-04-04
Abstract: The invention comprises a structure having at least two separate air chambers (7) enclosed by flexible, flat material (8) and having flexible bars (9) in the interior thereof for stabilizing an external shape of the air chambers (7). The structure is characterized in that the air chambers (7) form a wall structure (4) in the inflated state. By means of such a wall structure (4) - preferably in conjunction with a corresponding ceiling structure (16) - lightweight berths (1), particularly for aircraft crew, flight passengers, or transported injured persons, can be set up quickly and simply.
Patent CA-2690434-A1 (CA)
Inventor: PFEIFER ANDREA
IPC: A61K39/395
Filed: 2008-06-12
Abstract: The present application is related to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of disorders and abnormalities associated with amyloid protein such as Alzheimer's disease. The present application provides novel methods and compositions comprising highly specific and highly effective antibodies having the ability to specifically recognize and bind to specific epitopes from a range of ß-amyloid proteins. The antibodies enabled by the teaching of the present application are particularly useful for the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of diseases and disorders associated with amyloid plaque formation including secondary amyloidosis and age-related amyloidosis including, but not limited to, neurological disorders such as Alzheimer's Disease (AD).
Patent CA-2690756-A1 (CA)
Inventor: CARROLL WILLIAM A
IPC: A61P29/00
Filed: 2008-07-09
Abstract: The present application relates to cannabinoid receptor ligands containing compounds of formula (I) wherein A, R1, R2, and R3 are as defined in the specification. The present application also relates to compositions compris-ing such compounds, and methods of treating conditions and disorders using such compounds and compositions.
Patent CA-2692505-A1 (CA)
Inventor: IVEY CHRISTOPHER L
IPC: H04L9/32
Filed: 2010-02-09
Abstract: A system and method for restricting access to a computer system, resource, or network to live persons, and for preventing the execution of automated scripts via an interface intended for human interaction.   When queried for access to a protected resource, computer system, or network, the system will respond with a challenge requiring unknown petitioners to solve a visual puzzle before proceeding, said puzzle consisting of a collection of apparently random objects, and exploiting the natural human impulse to form semantic or symbolic associations between images of objects.  The puzzle objects are assembled into a composite test image which is designed to frustrate machine interpretation but is still easily interpreted by a human being.   The subject of the test must either recognize a semantic or symbolic association between two or more objects, or isolate an object that does not belong with the others, indicating their selection with the pointing device on their local computer.   If the subject of the test succeeds in passing the test, they are granted access to the requested resource, computer system, or network. If not, they are invited to attempt the test again, up to a configurable maximum retests, after which time their request is simply ignored.
Patent CA-2693326-A1 (CA)
Inventor: GALIPEAU JACQUES
IPC: A61K38/19
Filed: 2007-08-02
Abstract: A fusion protein comprising GM-CSF and IL-15 is described.    The fusion protein has unexpected immune suppressive properties and is useful in a variety of therapeutic applications.
Patent CA-2698469-A1 (CA)
Inventor: ZHANG DANLU
IPC: H04W16/00
Filed: 2008-09-26
Abstract: Techniques for scheduling users for transmission on the uplink in a wireless communication system are described.  A cell may perform interference cancellation for uplink transmissions and may observe lower effective noise and interference due to interference cancellation. The lower effective noise and interference may allow the cell to operate with a higher effective target load, which may support a higher overall throughput for the cell. In one design, an effective target load for a cell using interference cancellation may be determined, e.g., based on a target rise-over-thermal (RoT) for the cell and an interference cancellation efficiency factor. An available load for the cell may be determined based on the effective target load, which may be higher than a target load for the cell without interference cancellation. Users in the cell may then be scheduled for transmission on the uplink based on the available load.
Patent CA-2698784-A1 (CA)
Inventor: HECK WOLFGANG
IPC: G09G3/32
Filed: 2008-09-02
Abstract: A medical aid (110) is proposed, having an electrical power supply (130) and a display device (122) for visually displaying information. The display device (122) comprises a display (124) with at least one organic light-emitting material and is designed to be supplied with electrical power by means of the electrical power supply (130). The display device (122) furthermore comprises a drive apparatus (126), for driving the display (124), as well as a display driver (140). The drive apparatus (126) is designed to drive the display (124) in a regular operating mode in order to display the information. The drive apparatus (126) comprises a protective circuit (186) which is designed to monitor an electrical signal, which is provided by the electrical power supply (130), and to switch the display device (122) to a safe state in the event of any discrepancy of the electrical signal from a standard range.
Patent CA-2698795-A1 (CA)
Inventor: RAO DHARMARAJ RAMACHANDRA
IPC: C07C233/65
Filed: 2008-09-10
Abstract: There is provided a process for preparing sorafenib or a salt thereof comprising the use of a compound of formula (A), wherein R' is selected from the group consisting of hydrogen, -C(O)OA, -C(O)CX3, - OH C(O)NH2, -C(O)-NHOH or (a). There is also provided intermediate compounds of general formula (A), N-methyl-4-(4-ureidophenoxy)picolinamide, 4-(2-(methylcar-bamoyl)pyridin-4-yloxy)phenylcarbamate derivative and N-methyl-4-(4-(2,2,2-trihaloacetamido)phenoxy)picolinamide, processes for their preparation and their use in the preparation of sorafenib.
Patent CA-2700015-A1 (CA)
Inventor: O'DONOGHUE HUGH
IPC: G06Q10/00
Filed: 2008-09-26
Abstract: A method for generating recommendations for a user of a mobile device is provided. The user is associated with a service provider. A request for a recommendation is obtained. Data associated with the user and data on the content available to the user is retrieved from the service provider. A list of recommendations is generated based on an analysis of the retrieved user data.  The recommendations are generated by a plurality of different recommendation techniques.
Patent CA-2703994-A1 (CA)
Inventor: EVANS RONALD M
IPC: A61P19/04
Filed: 2008-11-06
Abstract: This application relates to methods of treating, preventing, and ameliorating fibrosis, such as fibrosis of the liver, kidney, or pancreas. In particular, the application relates to methods of using a vitamin D receptor agonist (such as vitamin D, vitamin D analogs, vitamin D precursors, and vitamin D receptor agonists precursors) for the treatment of fibrosis. Also disclosed are methods for screening for agents that treat, prevent, and ameliorate fibrosis.
Patent CA-2705126-A1 (CA)
Inventor: ANDERSON RICHARD JAMES ROBERT
IPC: F16K27/06
Filed: 2008-08-07
Abstract: A plug valve assembly having an inlet and an outletcomprisesa housing including a bore extending through the housing between the inlet and the outlet and acavityintersecting the bore, a plug mounted in the cavity for rotation between first and second positions. In the first position an orifice extending through the plug is aligned axially with the bore of housing to allow fluid to flow from the inlet to the outlet and in the second position fluid is prevented from flowing from the inlet to the outlet. Seals are located in the cavitybetween the plug and an inner surface ofsaid cavityand a plug retaining member is releasably attachable to the housing. A surface of the plug retaining memberlimits upward movement ofthe plug in the housing. The housing includes a reinforcement collar extending around the inner surface of the cavity.
Patent CA-2707839-A1 (CA)
Inventor: DESAI KISHOR C
IPC: E03D11/00
Filed: 2010-06-25
Abstract: This disclosure relates to a toilet bowl and seat which is user-friendly to individuals who are physically (or possibly mentally) disabled and especially wheelchair-bound people or even normal people with bad knees. The toilet seat and bowl shape is turned through 180 degrees relative to a conventional front-to-rear tapered seat and bowl shape in order to facilitate the ability to easily slide onto the toilet from the transportation device and easily slide backwards onto the same after use. A handle is also provided at the cistern front/rear of the toilet seat for support while standing up or sitting down during/after use and which is removable or fixed. Flushing also is easier because the tank is in front of the user and the flush handle may be provided on either side to suit the user.
Patent CA-2708149-A1 (CA)
Inventor: EVANS DEAN BRENT
IPC: A61P35/00
Filed: 2008-12-04
Abstract: The invention relates to a combination comprising vascular disrupting agent (VDA), such as 5,6-dimethylxanthenone-4-acetic acid or a pharmaceutically acceptable salt, ester or prodrug thereof; and one or more pharmaceutically active agents; pharmaceutical compositions comprising said combination; methods of treatment comprising said combination; processes for making said combination; and a commercial package comprising said combination.
Patent CA-2714296-A1 (CA)
Title: Humanized anti-c5ar antibodies
Inventor: WHITFELD PETER
IPC: A61K39/395
Filed: 2009-02-19
Abstract: The present invention is directed to humanized antibodies which bind the human C5a receptor and their use as therapeutic and diagnostic agents. The present invention is further directed toward nucleic acid sequences which encode said humanized antibodies, and their expression in recombinant host cells. In particular, the present invention is directed towards humanized antibodies derived from murine antibody 7F3 which specifically binds to the human C5a receptor.
Patent CA-2715254-A1 (CA)
Inventor: HART CHARLES E
IPC: A61L27/54
Filed: 2009-02-09
Abstract: The present invention relates to compositions and methods for use in osteodistraction procedures.    In one embodiment, a method of stimulating osteogenesis during and/or following bone distraction comprises providing a composition comprising a PDGF solution disposed in a biocompatible matrix and applying the composition to at least one site of bone distraction.
Patent CA-2716398-A1 (CA)
Inventor: LANE MARVIN
IPC: B65D47/00
Filed: 2010-10-04
Abstract: A drink additive lid system (10) is provided for selectively introducing a drink additive (12) to a beverage container (14) closed by the lid system (10). The system (10 ) includes a plurality of additive compartments (20), each compartment (20) containing a drink additive (12), and a lid (22) attachable to a beverage container (14) to close a fill opening (16) of the beverage container (14). The lid (22) carries the compartments (20) and includes a drinking port (67) to allow beverage to pass from inside of the container (14) to the mouth of a user, and an actuator (24) mounted to be sequentially positioned adjacent each additive compartment (20) to allow a user to sequentially dispense the additive (12) from each additive compartment (20) into the beverage container (14) by engaging the actuator (24) with the compartment (20).
Patent CA-2718629-A1 (CA)
Title: Poignee d'article culinaire avec coussin deformable
Inventor: PASQUINI LUDOVIC
IPC: B25G1/10
Filed: 2010-10-21
Abstract: L'invention concerne une poignée (1) d'article culinaire comportant un corps (2) rigide relié à l'article culinaire et au moins un coussin (10) déformable. Conformément à l'invention, ledit coussin (10) comporte une peau (11) en silicone destinée à être en contact avec la main, ladite peau (11) délimitant un réceptacle contenant un noyau solide dont la dureté shore est inférieure à la dureté de ladite peau (11).
Patent CA-2720757-A1 (CA)
Inventor: MCINTOSH JOSEPHINE
IPC: A41D3/02
Filed: 2009-04-10
Abstract: A coat including a torso portion defining a torso cavity and including pair of portions that are releasably connectable together. The coat further includes a skirt positioned in the torso cavity. The coat is configured such that when the coat is worn by a wearer and the portions are releasably connected together the skirt generally sealingly engages the wearer. The coat is further configured such that the skirt automatically generally sealingly engages the wearer when the coat is worn by the wearer and the portions are releasably connected without requiring any further action by the wearer.
Patent CA-2721397-A1 (CA)
Inventor: KIM JIN PIL
IPC: H04N21/462
Filed: 2009-04-30
Abstract: A method and apparatus for receiving a broadcasting signal for a real-time broadcasting service and a non-real-time broadcasting service are disclosed. The apparatus for receiving the broadcasting signal includes a receiving unit, a storage medium, a first processor and a second processor. The receiving unit receives and displays a broadcasting service in real-time. The first processor receives and decodes non-real-time content based on reception time information and identification information included in first signaling information, and stores the decoded non-real-time content in the storage medium. The second processor reads and presents the non-real-time content from the storage medium based on presentation time information and the identification information included in second signaling information, and displays the broadcasting service in real-time.
Patent CA-2721771-A1 (CA)
Inventor: YANG FRANK
IPC: B67D7/66
Filed: 2010-11-18
Abstract: A soap dispenser can be configured to dispense an amount of foam soap, for example, upon detecting the presence of an object. The dispenser can also include a gear-type pump that mixes air with liquid soap to create foamed pump. The dispenser can also include two pumps, one pump to feed liquid pump to a second pump that is configured to mix air with liquid soap to thereby create foamed soap. The dispenser can include a reservoir in its discharge passage to reduce unwanted dripping of foam soap or the liquid remains of foam soap, from a foam soap outlet.
Patent CA-2725428-A1 (CA)
Inventor: CHUAH BENG SIM
IPC: A61F6/04
Filed: 2009-04-28
Abstract: Provided are condoms and methods of making and using the same, the condoms having an elastomeric layer and a low melt wax bead which comprises an active ingredient mixed therein, wherein the bead is affixed on the interior surface of the elastomeric layer in the tip of the condom. Active ingredients can include spermicides such as nonoxynol-9 and vasodilators such as niacin, sildenafil citrate, and nitroglycerin and male desensitizing agents such as benzocaine. The bead can comprise a natural wax in combination with polyethylene glycol or it can be a polyethylene glycol-based wax. The exterior surface of the elastomeric layer is substantially free of the active ingredient.
Patent CA-2726768-A1 (CA)
Inventor: COLLINGWOOD TREVOR
IPC: C12N15/00
Filed: 2009-06-10
Abstract: Disclosed herein are methods and compositions for generation of Bak- and/or Bax-deficient cell lines using engineered nucleases.
Patent CA-2727114-A1 (CA)
Title: Surface active blocked isocyanates and coating compositions thereof
Inventor: LIN JUN
IPC: C09J183/04
Filed: 2009-07-23
Abstract: Disclosed herein is a surface active adhesion promoting agent and a coating composition comprising the surface active adhesion promoting agent. The adhesion promoting agent is a blocked isocyanate functional siloxane containing material. Addition of small amount of the adhesion promoting agent to a coating composition, especially clearcoat compositions, helps to provide adhesion to a variety of materials that may be subsequently applied to the coating composition.
Patent CA-2730933-A1 (CA)
Inventor: WEBER ERIC R
IPC: C07K19/00
Filed: 2009-07-15
Abstract: The present invention provides novel, modified pokeweed antiviral proteins, nucleic acids that encode the proteins, conjugates that incorporate the proteins, and methods to make and use the proteins. The present invention also provides methods to administer the conjugates to animals, for the purpose of directing toxin to particular cells.
Patent CA-2731919-A1 (CA)
Title: New compounds
Inventor: TREU MATTHIAS
IPC: A61P35/00
Filed: 2009-07-28
Abstract: The present invention encompasses compounds of general formula (1), wherein R1 to R4 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use for preparing a medicament having the above-mentioned properties.
Patent CA-2735569-A1 (CA)
Title: Dispositif de mesure du debit
Inventor: UEDA NAOTSUGU
IPC: G01F1/00
Filed: 2009-08-03
Abstract: Un circuit d'écoulement secondaire est formé à l'extérieur d'un tuyau d'écoulement principal (42) qui comporte un circuit d'écoulement principal (43). Un orifice (49) limitant l'écoulement d'un gaz est prévu à l'intérieur du circuit d'écoulement principal (43). Le circuit d'écoulement secondaire est constitué de deux circuits d'écoulement d'entrée (56) raccordés en amont de l'orifice (49), d'un deuxième circuit d'écoulement secondaire (59) dont les deux extrémités sont reliées aux extrémités aval des circuits d'écoulement d'entrée (56), de deux circuits d'écoulement de sortie (57) raccordés en aval de l'orifice (49), d'un deuxième circuit d'écoulement secondaire (60) dont les deux extrémités sont raccordées aux extrémités amont des circuits d'écoulement de sortie (57), et d'un circuit d'écoulement de détection (61) dont les deux extrémités sont raccordées au centre du deuxième circuit d'écoulement secondaire (59) et au centre du deuxième circuit d'écoulement secondaire (60), et dans lequel est placé un élément (47) de détection d'écoulement. L'extrémité amont du circuit d'écoulement de détection (61) est positionnée plus près de l'amont du circuit d'écoulement principal (43) que les deux extrémités du deuxième circuit d'écoulement secondaire (59), et l'extrémité aval du circuit d'écoulement de détection (61) est positionnée plus près de l'aval du circuit d'écoulement principal (43) que les deux extrémités du deuxième circuit d'écoulement secondaire (60).