baber/WOPTO huggingface dataset:
Patent JP-H0565106-B2 (JP)
Inventor: OOHARA HIROTAKA
IPC: G01N33/50
Filed: 1987-09-22
Abstract: This invention provides a method of determining the behavior of drugs in living bodies, particularly those which contain a variety of active ingredients, like biologicals, natural drugs and crude-drug preparations. It comprises administering a drug being tested to an animal, taking a blood sample from that animal, deproteinizing the plasma separated from the blood, intravenously administering the deproteinized plasma thus prepared to a different test animal, and examining the effect of drug exhibited in that test animal. The amount of active ingredients absorbed into the blood can be estimated by this indirect method even with special drugs including a variety of unknown and trace components.
Patent JP-H0249549-B2 (JP)
IPC: H01L23/538
Filed: 1983-12-28
Abstract: A multilayer wiring substrate composed of organic dielectric layers with wiring layers disposed therein supports large-scale integrated circuit chips and bonding pads. To prevent damage to the wiring layers when wires from the integrated circuit chips are attached to the bonding pads by thermocompression bonding, a metallic layer is interposed between the wiring layers and the bonding pads.
Patent JP-H0790533-B2 (JP)
IPC: B28B1/08
Filed: 1985-11-08
Abstract: Method and device for the casting of concrete products by means of a continuous slide-casting method. The concrete mix is compacted by displacing one or several walls of the slide-casting mould structure. The wall (5) of the slide-casting mould structure is displaced along a predetermined path of movement while facing the forming member (3) forming the cavity and moving eccentrically relative its centre axis or moving back and forth around an articulated shaft.
Patent JP-H0536016-B2 (JP)
IPC: A23L29/00
Filed: 1983-12-29
Abstract: Foodstuffs, chewing gum, tooth paste and pharmaceutical preparations having anti-caries activity, containing at least one vitamin K (including compounds chemically related with vitamin K) as anti-caries agent. Foodstuffs, chewing gum, tooth paste and pharmaceutical preparations having anti-caries activity, containing a combination of at least one vitamin K (including compounds chemically related with vitamin K) on the one hand, and on or more fluorine compounds on the other hand, as anti-caries agent. Milk or a product derived from one or more milk constituents, such as cheese, as a possible basis of the said foodstuffs. Processes for preparing the said products.
Patent JP-H06101361-B2 (JP)
IPC: H01R13/05
Filed: 1992-09-24
Abstract: A contact element in the form of a spring contact jack or spring plug pin has a plurality of mutually laterally disposed spring contacts which can be attached at one end to a support piece and which are radially curved in order to provide contact with an opposing contact; and further relates to a method of manufacturing the contact element.
Patent JP-4709339-B2 (JP)
IPC: H01L21/52
Filed: 1999-09-09
Granted: 2011-06-22
Abstract: PROBLEM TO BE SOLVED: To obtain an electrical-insulating heat-conductive adhesive capable of effectively dissipating heat generated from parts of semiconductor elements, power sources, light sources and the like which are used in electric appliances, a bonding method, and an electronic part having excellent heat dissipation properties. SOLUTION: A heat-conductive adhesive is obtained by compounding polybenzazole staple fibers with an adhesive polymer. A bonding method comprises allowing a heat-conductive adhesive obtained by compounding polybenzazole staple fibers with an adhesive polymer to be present between adherends to effect bonding in a state that the polybenzazole staple fibers in the heat conducting adhesive have been oriented to a definite direction by an external magnetic field. An electronic part is obtained by allowing a heat- conductive adhesive obtained by compounding polybenzazole short fibers with an adhesive polymer to be present between an exothermic element and a heat transfer member to effect bonding in a state that the polybenzazole staple fibers in the heat-conductive adhesive have been oriented in a definite direction by an external magnetic field.
Patent JP-3454452-B2 (JP)
IPC: B09B5/00
Filed: 1995-09-12
Granted: 2003-10-06
Abstract: Used dry cells are sorted into ultra-high power manganese dry cells and high power manganese dry cells including alkaline manganese cells. Line (I) includes crushing the ultra-high power manganese dry cells into fragments, sieving the fragments to collect a first fraction of depolarizer mass and a second fraction of metal casings, calcining the first fraction to form manganese and zinc oxides, and processing the oxides into a ferrite having a higher MnO/ZnO ratio. Line (II) includes crushing the high power manganese dry cells including alkaline manganese cells into fragments, sieving the fragments to collect a third fraction of depolarizer mass, adding zinc cans from the second fraction to the third fraction, calcining the mixture to form manganese and zinc oxides, and processing the oxides into another ferrite having a lower MnO/ZnO ratio. <IMAGE>
Patent JP-2691149-B2 (JP)
IPC: C12Q1/6869
Filed: 1995-10-17
Granted: 1997-12-17
Abstract: DNA polymerases are provided which do not discriminate significantly against incorporation of a dideoxynucleotide compared to a deoxynucleotide. DNA polymerases having a reduced discrimination against dideoxynucleotides may be obtained by modifying the nucleotide binding site of a wild type DNA polymerase. The DNA polymerases are particularly useful for DNA sequencing. <IMAGE>
Patent JP-2756382-B2 (JP)
IPC: B23B27/08
Filed: 1991-10-18
Granted: 1998-05-25
Abstract: A cutting tool for expanding or opening up the diameter of boreholes includes at least one reversible knife plate with a front surface. The knife plate can be clamped with at least one clamping shoe into a recess provided in a cutter head. The front surface of the knife plate has at least two grooves which extend essentially parallel and preferably symmetrical with respect to the longitudinal axis of the knife plate. The grooves cooperate with projections provided on the contact surface of the clamping shoe facing the front surface of the knife plate and form a positively locked connection therewith.
Patent JP-3145813-B2 (JP)
IPC: A61P43/00
Filed: 1992-10-30
Granted: 2001-03-12
Abstract: A process for producing a compound of formula I: <CHEM> comprising reacting 5-(2-fluorophenyl)-1H-tetrazole with a Grignard reagent to produce the desired product is disclosed. Novel compounds produced by this process for use as intermediates in making certain angiotension II antagonists are also disclosed.
Patent JP-2633274-B2 (JP)
IPC: B60B35/18
Filed: 1987-12-28
Granted: 1997-07-23
Abstract: An automobile wheel bearing unit of the kind which has an external member (1) to be mounted on the chassis of an automobile, an internal member (2) on one end of which is mounted a wheel, rolling elements (7, 8) interposed between the external member (1) and internal member (2), and a cage (9). The internal member (2) is rotatably mounted to the external member (1) via the rolling elements (7, 8) by a nut (6). An annular member (10) having a plurality of projections (10a) on an end face thereof is mounted on the other end of the internal member (2) opposite to the end thereof to which the wheel is mounted, and rotates in conjunction with the internal member (2). The nut (6) and annular member (10) are covered with a sealing member (11) mounted on the external member (1). A rotational detector (12) is mounted to the sealing member (11), and positioned between an inner peripheral surface of the sealing member (11) and an outer peripheral surface of the nut (6) in a manner facing the projections (10a) of the annular member (10) and detects a rotational speed of the annular member (10). The rotational detector (12) so sealed can detect the rotational speed with good precision over an extended period.
Patent JP-4700777-B2 (JP)
IPC: C07D249/12
Filed: 1999-12-07
Granted: 2011-06-15
Abstract: The present invention is related to an improved process for the commercial preparation of substituted aminotriazolinones, which are known intermediates in the preparation of herbicidal active compounds. In particular, this invention relates to the preparation of 4-amino-1,2,4-triazolin-5-ones, and more particularly to the preparation of 3-isopropyl-4-aminotriazolinone. The process of the invention includes reacting an oxadiazolinone with hydrazine hydrate in the absence of a solvent. In a preferred embodiment, the hydrazine hydrate is mixed with a basic compound, preferably aqueous sodium hydroxide.
Patent JP-3082035-B2 (JP)
IPC: F23G7/06
Filed: 1997-12-26
Granted: 2000-08-28
Abstract: The reactor has a conically upward-widening diffuser (2), which together with a cylindrical duct (4) and a concentrator (5), forms a Venturi nozzle inlet for the process gases. Between the duct and the diffusor wall (3), an annular base edge zone (6) has evenly distributed base-openings (10,10') concentric with the cylindrical duct for auxiliary gas flow (H) to enter through. Some of the base-openings at least have nozzles (9) for the auxiliary gas flow jets. An outlet for coarse ash (11) is positioned above the base edge zone in the bottom part of the diffuser.
Patent JP-2594900-B2 (JP)
IPC: C12N15/63
Filed: 1984-03-23
Granted: 1997-03-26
Abstract: This invention relates to multichain polypeptides or proteins and processes for their production in cells of host organisms which have been transformed by recombinant DNA techniques. According to a first aspect of the present invention, there is provided a process for producing a heterologous multichain polypeptide or protein in a single host cell, which comprises transforming the host cell with DNA sequences coding for each of the polypeptide chains and expressing said polypeptide chains in said transformed host cell. According to another aspect of the present invention there is provided as a product of recombinant DNA technology an Ig heavy or light chain or fragment thereof having an intact variable domain. The invention also provides a process for increasing the level of protein expression in a transformed host cell and vectors and transformed host cells for use in the processes. <IMAGE>
Patent JP-H0646196-B2 (JP)
IPC: C07K16/08
Filed: 1985-05-03
Abstract: A mammalian monoclonal receptor is produced by a hybridoma formed by fusion of cells from a myeloma cell line and lymphocytes that produce antibodies that react with a viral antigen from a mammal immunized with cytomegalovirus-infected cells. The monoclonal receptor reacts with the viral antigen in a diagnostic system to detect the presence of cytomegalovirus in a biological sample.
Patent JP-4054058-B2 (JP)
IPC: C12N15/11
Filed: 1995-06-29
Granted: 2008-02-27
Abstract: Nucleic acid molecules and proteins useful for regulating the expression of genes in eukaryotic cells and organisms are disclosed. The invention provides a transcriptional activator fusion protein which binds to tet operator sequences and stimulates transcription of a tet operator-linked gene in the presence, but not the absence, of tetracycline (or analogue thereof). The invention further provides transcriptional inhibitor fusion proteins which inhibit transcription of a tet operator-linked gene in a regulated manner. In one embodiment, the inhibitor fusion protein binds to tet operator sequences in the absence, but not the presence, of tetracycline (or analogue). In another embodiment, the inhibitor fusion protein binds to tet operator sequences in the presence, but not the absence, of tetracycline (or analogue). The transcriptional activator and inhibitor fusion proteins of the invention can be used in combination to regulate expression of one or multiple tet operator-linked genes. Novel tet operator-containing transcription units which allow for coordinate or independent tetracycline-regulated expression of two or more genes by the transcriptional modulators of the invention are also disclosed. Kits including the components of the regulatory system are also encompassed by the invention. <IMAGE>
Patent JP-2885510-B2 (JP)
IPC: A61B5/0408
Filed: 1990-02-08
Granted: 1999-04-26
Abstract: An adhesive composition suitable for use as an in-line contact adhesive for electrotransport drug delivery systems.
Patent JP-H055504-B2 (JP)
IPC: A61B17/3211
Filed: 1986-09-16
Abstract: A scalpel is set forth having a handle with a blade at one end which defines a first depth of cut. To transform the scalpel for cutting to a lesser, second depth of cut a removable guard is provided. The guard is attached to the scalpel handle with a bayonet-type connection and has a tip to be disposed near one side of the blade. When the guard is attached, the blade projects past the tip a predetermined amount to define the second depth of cut. Guards are constructed for right or left hand preference.
Patent JP-3315405-B2 (JP)
IPC: A61P7/00
Filed: 1992-02-12
Granted: 2002-08-19
Abstract: Receptor-induced binding sites (RIBS) expressed in a ligand when that ligand is bound in a complex with a receptor are disclosed, as are polypeptides that correspond in amino acid residue sequence with a RIBS expressed by a receptor-ligand complex. Particularly-preferred polypeptides correspond to a RIBS amino acid sequence of the gamma chain of human fibrinogen. Monoclonal antibodies that immunoreact with a RIBS but do not substantially immunoreact with either the ligand or the receptor when free in solution are also disclosed, as are hybridomas secreting those antibodies, and methods of making and using such antibodies.
Patent JP-2814305-B2 (JP)
IPC: G11B7/24076
Filed: 1992-10-19
Granted: 1998-10-22
Abstract: PCT No. PCT/GB92/01920 Sec. 371 Date Apr. 7, 1994 Sec. 102(e) Date Apr. 7, 1994 PCT Filed Oct. 19, 1992 PCT Pub. No. WO93/08565 PCT Pub. Date Apr. 29, 1993.An optical data storage disc, for example, a compact disc, has one side formed with a pattern of indentations defining a digital data recording, and this side is metallized and further coated with a layer, which is embossed with a relief pattern defining a holographic image. The hologram may extend across the whole surface of the disc and is visible from the top side of the disc, while digital information is readable in a conventional manner using a laser directed at the underside of the disc.
Patent JP-2950993-B2 (JP)
IPC: A61K33/18
Filed: 1993-09-16
Granted: 1999-09-20
Abstract: Stable, aqueous detergent-iodine germicidal use compositions and concentrates adapted for application to animal or human skin are provided which have desirable detergent:iodine ratios of from about 2-4.5. The compositions and concentrates include a polyethoxylated polyoxypropylene block copolymer (poloxamer) as the complexing agent, wherein the polyoxypropylene moiety has an average molecular weight of at least 2600 and a polyoxyethylene content of from about 30%-75% by weight, in combination with from about 0.1%-5% by weight average available iodine on a nominal basis. Use of the defined class of poloxamers allows formulation of both high and low temperature stable compositions and concentrates. Other ingredients such as emollients, buffering agents and viscosity improvers can also form a part of the use compositions and concentrates.
Patent JP-3710482-B2 (JP)
IPC: C08G63/08
Filed: 1996-09-09
Granted: 2005-10-26
Abstract: Poly(lactones) are provided. The poly(lactones) are obtained by polymerization of a lactone with an initiator system comprising at least one polyfunctional initiator. The poly(lactones) have a shear viscosity at some temperature in the range of from 35 to 45° C. above the melting temperature of the poly(lactone) of at least 6 kPas at 0.1 s-1 shear rate and no greater than 3.5 kPas at 100 s-1 shear rate, and a shear viscosity activation energy of greater than 40 kJ/mol. Preferably, the poly(lactone) is poly(caprolactone).
Patent JP-2994036-B2 (JP)
IPC: G01N21/64
Filed: 1991-07-12
Granted: 1999-12-27
Abstract: PCT No. PCT/FR91/00566 Sec. 371 Date Sep. 16, 1994 Sec. 102(e) Date Sep. 16, 1994 PCT Filed Jul. 12, 1991 PCT Pub. No. WO92/01224 PCT Pub. Date Jan. 23, 1994The invention relates to a method of reducing interference in a fluorescent assay of an analyte, which comprises adding fluoride ions to the measuring medium, and to its use in a fluorescent method of detecting and/or determining an analyte in a medium which may contain it.
Patent JP-3369561-B2 (JP)
IPC: C07D231/04
Filed: 1993-02-01
Granted: 2003-01-20
Abstract: PCT No. PCT/CH93/00026 Sec. 371 Date Sep. 27, 1993 Sec. 102(e) Date Sep. 27, 1993 PCT Filed Feb. 1, 1993 PCT Pub. No. WO93/15091 PCT Pub. Date Aug. 5, 1993.Novel, racemic and optically active phosphorus compounds of the formula    <IMAGE>  I  wherein R signifies lower alkyl or lower alkoxy and R1 represents lower alkyl, cycloalkyl or substituted phenyl, are described. The compounds of formula I are useful in the form of complexes with a metal of Group VIII as catalysts for asymmetric hydrogenations and for enantioselective hydrogen displacements in prochiral allylic systems.
Patent JP-3014768-B2 (JP)
IPC: C11D3/22
Filed: 1996-07-31
Granted: 2000-02-28
Abstract: PCT No. PCT/FR96/01206 Sec. 371 Date Apr. 2, 1998 Sec. 102(e) Date Apr. 2, 1998 PCT Filed Jul. 31, 1996 PCT Pub. No. WO97/12954 PCT Pub. Date Apr. 10, 1997The invention relates to a descaling formulation comprising cellulose microfibrils, in which at least 80% of the cells have primary walls and not more than 20% of the cells have secondary walls, with a degree of crystallinity of not more than 50%. The pH of the formulation is less than or equal to 1 and more particularly less than or equal to 0.5.
Patent JP-4011109-B2 (JP)
IPC: C07D407/12
Filed: 1995-11-08
Granted: 2007-11-21
Abstract: PCT No. PCT/GB95/02606 Sec. 371 Date May 12, 1997 Sec. 102(e) Date May 12, 1997 PCT Filed Nov. 8, 1995 PCT Pub. No. WO96/15118 PCT Pub. Date May 23, 1996The invention concerns aniline derivatives of formula I    <IMAGE>  (I)  wherein m is 1, 2 or 3, n is 0, 1, 2 or 3, Q is phenyl or naphthyl or a 5- or 6-membered heteroaryl moiety containing 1, 2 or 3 heteroatoms selected from oxygen, nitrogen and sulfur, and X, R1 and R2 are defined in the claims; or pharmaceutical compositions containing them, and the methods of using the compounds as tyrosine kinase inhibitors and for the treatment of proliferative diseases such as cancer.
Patent JP-3069375-B2 (JP)
IPC: B22D11/00
Filed: 1995-01-19
Granted: 2000-07-24
Abstract: PCT No. PCT/DE95/00093 Sec. 371 Date Jul. 29, 1996 Sec. 102(e) Date Jul. 29, 1996 PCT Filed Jan. 20, 1995 PCT Pub. No. WO95/20446 PCT Pub. Date Aug. 3, 1995Molten metal is poured into a continuous casting mold having a rectangular mold exit opening to produce a rectangular metal strand having a liquid core, a width and a thickness. A convex shape is imparted to the rectangular strand along at least a part of the width thereof downstream of the casting mold by arranging a plurality of oppositely disposed guide rolls immediately downstream of the rectangular mold exit opening so that the cast strand while travelling from the mold exit opening through the plurality of guide rolls expands along at least part of its width no more than 8% of the strand thickness, thereby preventing snaking of the strand.
Patent JP-4600893-B2 (JP)
IPC: C04B35/80
Filed: 1997-11-07
Granted: 2010-12-22
Abstract: A method for isothermic, isobaric chemical vapor infiltration (CVI) of refractory substances, especially of carbon (C) and silicon carbide (SiC), based on diffusion in a porous structure, whereby the pressure of the gas or partial pressure of an educt gas contained in the gas and the dwell time of the gas in the reaction zone are set at a given temperature in the reaction zone so that a deposition reaction occurs in the porous structure in the area of pressure or partial pressure of the saturation adsorption of the gaseous compounds forming the solid phase, saturation adsorption meaning that the deposition speed remains substantially constant at increased pressure of the gas or partial pressure of the educt gas. The reaction of the educt gas is limited in such a way that no more than 50% of the elements in the educt gas as it flows through the reaction zone are deposited as a solid phase in the porous structure.
Patent JP-3622979-B2 (JP)
IPC: C09D7/47
Filed: 1996-02-01
Granted: 2005-02-23
Abstract: Polymeric flow modifiers having a weight average molecular weight of between 4,000 to 450,000 consisting essentially of polymerized monomers on a weight basis as follows: 40 to 96% C1 or C2 alkyl acrylate or mixtures thereof; 4 to 12% acrylic acid; and 0 to 48% copolymerized acrylic acid ester monomer.
Patent JP-3909345-B2 (JP)
IPC: B01L3/00
Filed: 1998-01-15
Granted: 2007-04-25
Abstract: We describe an assay device which comprises a substrate comprising (i) a porous material capable of chromatographically transporting a liquid and (ii) one or more test reagents for an assay provided on the porous material; and a doping polymer impermeable to the liquid which the porous material is capable of transporting, incorporated into a part of the porous material so as to define a channel in the porous material, the one or more test reagents being provided on the porous material in the channel defined therein. <IMAGE>
Patent JP-3833254-B2 (JP)
IPC: H02K21/38
Filed: 1996-05-30
Granted: 2006-10-11
Abstract: A self-starting brushless electric motor having a first motor part (stator) (11) with poles arranged in a row, said poles constituting ferromagnetic poles (13S) or permanent-magnet poles (14A), a second motor part (rotor) (12) with poles arranged in a row, said poles consisting of ferromagnetic poles (16A) or permanent-magnet poles and being arranged opposite the row of poles on the first motor part (11), wherein the motor part with salient ferromagnetic poles or, if both motor parts have salient ferromagnetic poles, at least one of the motor parts has a permanent-magnet pole, and also a magnetizing winding on the first motor part. The system of poles formed by the pole rows is magnetically asymmetrical in the direction in which the motor parts (11,12) are movable in relation to each other. <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE>
Patent JP-4264135-B2 (JP)
IPC: A61K31/505
Filed: 1997-05-02
Granted: 2009-05-13
Abstract: The present invention concerns the compounds of formulathe N-oxide forms, the pharmaceutically acceptable acid addition salts and stereochemically isomeric forms thereof, wherein Alk is C1-6alkanediyl or C3-6alkenediyl; R1 is hydrogen or C1-4alkyl; R2 and R3 each independently are hydrogen, C1-6alkyl or C3-7cycloalkyl; or R2 and R3 may also be taken together with the nitrogen atom to which they are attached, thus forming a pyrrolidine, a piperidine or a perhydro azepine ring; R4 is hydrogen or halo; Q is aryl, aryloxy, di(aryl)methyl or heteroaryl; aryl is naphthyl or phenyl, said naphthyl and phenyl may optionally be substituted; and heteroaryl is quinolinyl, isoquinolinyl, pyridinyl, thienyl, indolyl, 2,3-dihydro-1,4-benzodioxinyl, 2,3-dihydro-benzofuranyl or benzodioxolanyl; said heteroaryls may optionally be substituted; it further relates to processes for their preparation, compositions comprising them as well as their use as a medicine; compounds of formula (I) containing a radioactive isotope; a process of marking dopamine D4 receptor sites; and a process for imaging an organ are disclosed.