baber/WOPTO huggingface dataset:
Patent AU-2017225060-A1 (AU)
Title: Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
Inventor: CHARPENTIER EMMANUELLE
IPC: C07K19/00
Filed: 2017-09-07
Abstract: The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides methods of site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure provides methods of modulating transcription of a target nucleic acid in a target cell, generally involving contacting the target nucleic acid with an enzymatically inactive Cas9 polypeptide and a DNA-targeting RNA. Kits and compositions for carrying out the methods are also provided. The present disclosure provides genetically modified cells that produce Cas9; and Cas9 transgenic non-human multicellular organisms.
Patent AU-2017238088-A1 (AU)
Title: Determining prediction parameters for non-square blocks in video coding
Inventor: SEREGIN VADIM
IPC: H04N19/167
Filed: 2017-03-21
Abstract: A method of decoding video data comprising receiving a block of video data encoded using a position dependent intra prediction combination (PDPC) mode, the block of video data having a non-square shape defined by a width and a height, determining one or more PDPC parameters based on one or more of the width or the height of the block of video data, and decoding the block of video data using the PDPC mode and the determined PDPC parameters.
Patent AU-2017241807-A1 (AU)
Title: Medium, methods, cells and secreted factors for stem cell culture and therapy
Inventor: BETANCOURT ALINE M
IPC: C12N5/0775
Filed: 2017-03-30
Abstract: Described herein are methods and culture medium, useful for inducing polarization in multipotent stem cells. Additionally, described herein are multipotent cells produced by the methods and culture medium of this disclosure that are useful therapeutic agents. Also described herein are extracellular vesicles and factors secreted by multipotent cells that are produced by the methods and culture medium of this disclosure that are useful as therapeutic agents.
Patent AU-2017242765-A1 (AU)
Title: Method and device for registering biometric identity and authenticating biometric identity
Inventor: SUN YUANBO
IPC: H04L29/06
Filed: 2017-03-22
Abstract: The application provides method of registering a biometric identity and authenticating a biometric identity. The method is applicable to user equipment. The method comprises: transmitting to a service server a registration information request message comprising a service account identifier, receiving from an authentication server a registration information response message comprising a virtual account identifier; after biometric data passes a local identity verification, encapsulating into a registration request message an equipment identifier, the virtual account identifier, a biometric token and a biometric verification type corresponding to the biometric data that has passed the local identity verification, and a generated service public key; signing, using an equipment private key, the registration request message, and transmitting the same to the service server for the authentication server to store, after the forwarded registration request message passes a verification using an equipment public key, correspondence of the equipment identifier, the virtual account identifier, the biometric token, the biometric verification type, and the service public key for identity verification. The technical solution in the invention enhances security of registration and authentication processes.
Patent AU-2017245402-A1 (AU)
Title: Tolerogenic synthetic nanocarriers for generating cd8+regulatory t cells
Inventor: MALDONADO ROBERTO A
IPC: A61K39/00
Filed: 2017-10-12
Abstract: Abstract Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen- specific CDS+ regulatory T cells. See Fig. 2. WO 2012/149282 PCT/US2012/035405 FOXP3 1mphocyt.l CD3 . 8.60 FX353% 95.19 53.10 U 0u. FSC/SSC CD3 CD25 gated FSC CD3 CD25 CD4 Fig. 1 8- f o u 2 600f10 DLn I Ln F .-2 Fig. 2
Patent AU-2017257217-A1 (AU)
Title: Marker for prognosis of a clinical outcome of an autologous intervertebral disc cell transplantation, for progress assessment/progress monitoring of an autologous intervertebral disc cell transplantation, for assessing the quality of intervertebral disc cells, for assessing the quality of an implant and/or medication for novel therapies (ATMP) for the treatment of an intervertebral disc defect, and for diagnosis of an intervertebral and/or spinal column defect
Inventor: GAISSMAIER CHRISTOPH
IPC: G01N33/68
Filed: 2017-04-25
Abstract: The invention relates to markers for use in vitro in the prediction (prognosis) of a clinical outcome (so-called outcome prognosis) of an autologous intervertebral disc cell transplantation, in particular a matrix-associated autologous intervertebral disc cell transplantation, and/or progress assessment/progress monitoring of an autologous intervertebral disc cell transplantation, in particular a matrix-associated autologous intervertebral disc cell transplantation, and/or in the assessment of the quality of intervertebral disc cells, preferably for an autologous intervertebral disc cell transplantation, in particular for a matrix-associated autologous intervertebral disc cell transplantation, and/or in the assessment of quality of an implant and/or a medication for novel therapies (ATMP) for the treatment of an intervertebral disc defect and/or for the reconstruction of intervertebral disc tissue and/or in the diagnosis of an intervertebral disc defect, in particular a lumbar, preferably lumbar-sacral intervertebral disc defect, and/or spinal column defect, wherein the marker is selected from the group consisting of CTX-I, CTX-II, NTX-I, CPII, VEGF, C2C, MMP-3, hyaluronic acid, TNF-α, IL-1ra, IL-4, COMP, YKL-40 and combinations of at least two of said markers. The invention further relates to a corresponding in vitro method and to a corresponding kit.
Patent AU-2017259252-A1 (AU)
Title: System and method for latency-based queuing
Inventor: JOHN RHIDIAN
IPC: H04L47/56
Filed: 2017-04-28
Abstract: Embodiments of the present invention are directed to systems and methods for queuing and sending messages to recipients according to historical latency values associated with each recipient. In some embodiments, a plurality of messages are received, each message including a network address of a recipient. The messages are sent to the recipients by threads that remain active (i.e., cannot be used to send another message) until confirmation responses are received from the recipients. Latency times are measured between when the messages were sent and when the confirmation responses were received. The latency times may be used to assign future messages to queues designated by certain latency ranges.
Patent AU-2017274521-A1 (AU)
Title: Method of treating liver fibrosis
Inventor: MIAO ZHENHUA
IPC: A61K31/18
Filed: 2017-06-02
Abstract: A method of treating liver fibrosis with CCR2 antagonists is provided. The liver fibrosis may be associated with non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), emerging cirrhosis, non-cirrhotic hepatic fibrosis, type 2 diabetes mellitus (T2DM) or metabolic syndrome (MS).
Patent AU-2017275466-A1 (AU)
Title: Product merchandising systems and methods
Inventor: Nooli Praveen Kumar
IPC: F25B39/02
Filed: 2017-05-25
Abstract: A product merchandising system includes a housing having a top surface, two side surfaces spaced apart from one another defining a width-direction of the housing, and a front surface and rear surface spaced apart from one another defining a depth-direction of the housing. The system includes a product support system configured to support rows of products along a width of the housing, each row disposed at a position along the depth of the housing, the first row being towards the front surface of the housing. A cooling system includes a cooling heat exchanger generating an airflow, a deflector configured to direct the airflow through the cooling heat exchanger and towards a bottom of the housing, and a nozzle below the deflector and configured to direct the airflow towards a bottom of the housing through an outlet aperture and between a first two rows of products.
Patent AU-2017305160-A1 (AU)
Title: Internal combustion engine intake power booster system
Inventor: EVULET ANDREI
IPC: F02M29/00
Filed: 2017-07-19
Abstract: An internal combustion engine includes an intake conduit fluidically coupled to ambient fluid and having an internal cross-sectional area and an engine cylinder fluidically coupled to the intake conduit. A fluidic amplifier is disposed within the intake conduit and is fluidically coupled to the ambient fluid and engine cylinder. The amplifier is further fluidically coupled to a source of primary fluid and is configured to introduce the primary fluid and at least a portion of the ambient fluid to the engine cylinder.
Patent AU-2017352704-A1 (AU)
Title: Pyrazolopyrimidine compound as PI3K inhibitor and use thereof
Inventor: YE BAOHUAN
IPC: C07D519/00
Filed: 2017-10-18
Abstract: The present invention relates to the pyrazolopyrimidine compound of formula (I) and a pharmaceutically-acceptable salt thereof. Such compounds can be used to inhibit the activity of a fat kinase PI3K, and can also be used to treat diseases mediated by PI3K, such as cancers, inflammation and autoimmune diseases. The present invention also relates to a pharmaceutical composition containing such compounds, a method for preparing such compounds and the use of such compounds or pharmaceutical composition in preparing drugs for treating cancers, inflammation and autoimmune diseases mediated by PI3K.
Patent AU-2017366739-A1 (AU)
Title: Synthetic immune receptors and methods of use thereof
Inventor: CHAUDHARY PREET M
IPC: A61K39/00
Filed: 2017-12-02
Abstract: The disclosure provides synthetic immune receptors (SIRs), nucleic acids encoding the SIRs, methods of making and using the SIRs, in, for example, adoptive cell therapy.
Patent AU-2017371838-A1 (AU)
Title: A stable, self-dispersible, low foaming solid pesticide formulation
Inventor: LEVY SHLOMO
IPC: A01N43/707
Filed: 2017-12-07
Abstract: The present subject matter relates to a stable pesticidal formulation which exhibits improved dispersibility in cold water and full compatibility with fertilizers.
Patent AU-2017375040-A1 (AU)
Title: Methods of determining colorectal cancer status in an individual
Inventor: O'TOOLE PAUL
IPC: C12Q1/68
Filed: 2017-12-15
Abstract: A method of determining colorectal cancer status in an individual, which comprises abundance profiling of the individual's microbiome.
Patent AU-2017380556-A1 (AU)
Title: Railway side-tipping wagon
Inventor: ZHANG XIANHUA
IPC: B61D9/06
Filed: 2017-07-20
Abstract: A railway side-tipping wagon comprises: an underframe assembly (1); a wagon assembly (2) installed at the top of the underframe assembly (1); a side door (3) hinged to one side of the wagon assembly (2); a side door opening/closing mechanism (4) for controlling opening and closing of the side door (3); a bogie (8) installed at the bottom of the underframe assembly (1); an air brake device (5) installed at the bottom of the underframe assembly (1) and capable of performing service braking on a wheel of the bogie (8); a parking brake device (6) installed at the bottom of the underframe assembly (1) and capable of performing parking braking on the wheel of the bogie (8); and a coupler cushioning device (9) installed at an end portion of the underframe assembly (1). The present invention further comprises a pneumatically-controlled hydraulic system (7) for controlling multiple side door opening/closing operation cylinders (4.1) of the side door opening/closing mechanism (4).
Patent AU-2018204068-A1 (AU)
Title: Parametric chassis system for vehicles, comprising four suspension elements, incorporating a lateral torsion bar and co-axial damper unit, in a box-module, that allows central location of heavy items, such as batteries.
Inventor: HATZIKAKIDIS DIMIITRIOS A
IPC: B60G3/12
Filed: 2018-06-07
Abstract: PARAMETRIC CHASSIS SYSTEM FOR VEHICLES, COMPRISING FOUR SUSPENSION ELEMENTS, INCORPORATING A LATERAL TORSION BAR AND CO-AXIAL DAMPER UNIT, IN A BOX-MODULE, THAT ALLOWS CENTRAL LOCATION OF HEAVY ITEMS, SUCH AS A chamber cluster including one or more chambers for a co-axial damper unit of a suspension module, each chamber of the chamber cluster comprising a damping wing, enclosed in a flexible component, in contact with an inner surface of the chamber cluster, wherein the wing is rotatable in a volume space, formed in a portion of the chamber, that is filled with a viscous fluid, a pressure of the viscous fluid being controlled by a pressure control valve, wherein the wing is driven by motion of a torsion bar of a suspension module that rotates about an axis, the torsion bar being rigidly attached to a first drive gear, which drives the wing via a coupling of an idle gear, and a second drive gear, connected to the wing, wherein the wing is within the volume space, that is sealed by outer seals, and inner seals, sealing the torsion bar, the chamber cluster, a bulkhead and an assembly cover, wherein an outer gear locator bracket, and an inner gear locator bracket orient orienting the axes of rotation of the idle gear and the drive gear, wherein the motion of the wing in the volume space provides damping for the torsion bar the damping being variable, by changing a viscosity of the viscous fluid with an electromagnetic device attached to the chamber, wherein the flexible component has a W-shaped cross-section, with a closed top section and an open lower section, that allows the enclosure of the wing into the flexible component, and allows the partial sealing of the volume space, during rotation of the wing, thus achieving damping.
Patent AU-2018233619-A1 (AU)
Title: Herbicidal azines
Inventor: VOGT FLORIAN
IPC: A01P13/00
Filed: 2018-03-05
Abstract: The present invention relates to diaminotriazine compounds of the formula (I) and to their use as herbicides. The present invention also relates to agrochemical compositions for crop protec- tion and to a method for controlling unwanted vegetation, wherein all variable as are defined in claim 1 including their agriculturally acceptable salts.
Patent AU-2018247101-A1 (AU)
Title: Method and use to prevent deposits in engine
Inventor: ROSS ALAN NORMAN
IPC: C10L1/19
Filed: 2018-03-28
Abstract: A diesel fuel composition comprising as an additive an ester compound which is the reaction product of an optionally substituted polycarboxylic acid or an anhydride thereof and a compound or formula H-(OR)
Patent AU-2018249465-A1 (AU)
Title: Magnetic camera coupling system
Inventor: FULLER RYAN
IPC: G02C5/00
Filed: 2018-04-02
Abstract: A camera system including an integrated coupling system configured to releasable couple the camera system with a user head accessory such as a pair of glasses, a hat, a headband, an item of jewelry, etc. The camera module may have an outer dimension smaller than three cubic inches and may further include a data coupler, battery, lens, image sensor, circuit board, and microphone. The camera module may transmit and receive data from the portable computer device including video data and on/off recording, respectively. A magnetic coupling system configured to selectively releasably couple the camera module directly with the user head accessory including magnet(s) disposed within each of the camera module and the user head accessory.
Patent AU-2018250526-A1 (AU)
Title: Point density illustration
Inventor: COHEN ASSAF
IPC: A61B5/06
Filed: 2018-10-22
Abstract: Methods, computing systems and computer software products implement embodiments of the present invention that include receiving, by a processor, respective coordinates for multiple points on a surface, and rendering an image of the surface on a display screen. For each given point among the multiple points, a density of the points within a region surrounding the given point is computed, and the given point on the surface with a point size that is inversely related to the computed density is rendered on the display screen. I Io uU-) u-- I1
Patent AU-2018253992-A1 (AU)
Title: Cone crusher
Inventor: MCCLOSKEY JAMES PASCHAL
IPC: B02C2/00
Filed: 2018-04-17
Abstract: The present disclosure provides a generally cylindrical bowl support for a cone crusher which includes a plurality of evenly, circumferentially spaced ears around the periphery of the support. The ears are designed to have clamping cylinders mounted thereto to provide protection from tramp iron and the like passing through the cone crusher. A plurality of thickened ribs are defined in the support, at least some of the thickened ribs extending downwardly from the ears to form abutting polygon configurations to spread and absorb forces from a crushing operation. Other ones of the ribs define at least one circumferentially-extending, continuous ring forming portions of the polygons.
Patent AU-2018256367-A1 (AU)
Title: Methods for identifying compounds
Inventor: SIGEL ERIC ALAN
IPC: C40B40/10
Filed: 2018-04-18
Abstract: The present disclosure provides virtual screening methods utilizing data sets from nucleotide-encoded libraries (e.g., DNA-encoded libraries). These methods allow for high confidence predictions of binding interactions between candidate compounds and proteins of interest useful for the development of therapeutics.
Patent AU-2018325445-A1 (AU)
Title: Ectonucleotide pyrophosphatase-phosphodiesterase 1 (ENPP-1) inhibitors and uses thereof
Inventor: GALLATIN WILLIAM MICHAEL
IPC: C07D401/14
Filed: 2018-08-31
Abstract: Disclosed herein are methods and compounds of augmenting and enhancing the production of type I IFNs
Patent AU-2018334590-A1 (AU)
Title: Self-priming water turbine-driven reel sprinkler irrigation machine
Inventor: QIU ZHIPENG
IPC: A01G25/09
Filed: 2018-06-25
Abstract: The present invention discloses a self-priming water turbine-driven reel sprinkler irrigation machine, comprising a framework, a plug board, a reel, a PE pipe, a water turbine driving device, a sprinkler wagon, and a self-priming device. The framework comprises an underframe, a reel support frame, a plug board support frame, and a wheel assembly. The bottom of the underframe is provided with an underframe rotary device, and the underframe rotary device comprises a rotary bearing and a chassis support member. An inner ring of the rotary bearing is fixedly mounted and connected to the underframe, and an outer ring of the rotary bearing is fixedly mounted and connected to the chassis support member. A telescopic front support is further disposed at the front part of the underframe. The wheel assembly comprises a wheel support beam, a wheel, and a wheel lifting hydraulic cylinder. The self-priming device comprises a water pump, a pumping hose, and a filtering mechanism. The self-priming water turbine-driven reel sprinkler irrigation machine enables easy adjustment of the sprinkler irrigation direction and flexible turnaround of the reel sprinkler irrigation machine under the premise of self-pumping water for sprinkler irrigation operation, and is especially suitable for sprinkler irrigation operation in the fields adjacent to irrigation canals and without a pressurized water hydrant.
Patent AU-2018348303-A1 (AU)
Title: Active ingredient compositions comprising N-alkenoyl-N-alkylglucamides and the use thereof
Inventor: BAUR PETER
IPC: A01N43/82
Filed: 2018-10-09
Abstract: The invention relates to active ingredient compositions comprising a) one or more active substances, and b) one or more N-alkenoyl-N-alkylglucamides of the formula (I) in which R1 is a linear or branched alkenyl group which has (7) to (16) carbon atoms and has a non-terminal double bond or a plurality of conjugated or non-conjugated double bonds, and R2 is an alkyl group having (1) to (4) carbon atoms. The compounds of formula I can be used for reducing drift and for improving wettability when appyling active ingredient compositions.
Patent AU-2018351614-A1 (AU)
Title: Filter press and method for separating the solid components from the liquid components of a slurry
Inventor: GRÖNVALL LARS
IPC: B01D25/19
Filed: 2018-10-18
Abstract: The invention relates to a filter press (1,100,200) for separating the solid components from the liquid components of a slurry comprising side beams (4) and a plurality of filter plates (6,106,206) oriented at right angles to 5 the longitudinal direction of the side beams wherein said filter plates are adapted to move along said side beams, a stationary end (5,105,205) arranged on one end of the side beams, a movable head (8,108,208) adapted to transport said filter plates along the side beams, a press system (26,126,226) adapted to exert a closing pressure on said filter plates to press 10 the filter plates against each other and wherein the press system (26, 126, 226) comprises at least one actuator (27, 127, 227) at least one electrically driven actuator (27,127,227) adapted to generate an axially directed force which is exerted on the filter plates by means of the movable head (8,108,208). The invention also relates to a method for separating the solid 15 components from the liquid components of a slurry.
Patent AU-2018355821-A1 (AU)
Title: Air gap device and liquid disinfecting cartridge comprising the air gap device for a medical instrument cleaning and disinfecting apparatus
Inventor: KNORTH HENNY HERMANUS HENDRIK
IPC: A61L2/26
Filed: 2018-10-26
Abstract: The present invention relates to an air gap device for a medical instrument cleaning and disinfecting apparatus, the device comprising a housing having a first end adapted to allow liquid to enter the device and a second end adapted to discharge liquid from the device, wherein the first end comprises means for connecting the device to a disinfecting unit. The device further comprises handling means for handling the device. The present invention relates to a liquid disinfecting cartridge comprising the air gap device and the liquid disinfecting unit. Further, the present invention relates to a liquid disinfecting unit and air gap device intended for use in the liquid disinfecting cartridge and relates to an assembly of the medical instrument cleaning and disinfecting apparatus and the liquid disinfecting cartridge. The invention also relates to a method for interchangeably coupling the liquid disinfecting cartridge with the medical instrument cleaning and disinfecting apparatus.
Patent AU-2018371776-A1 (AU)
Title: Methods and materials for assessing and treating obesity
Inventor: ACOSTA ANDRES J
IPC: G01N33/48
Filed: 2018-11-21
Abstract: This document relates to methods and materials for assessing and/or treating obese mammals (e.g., obese humans). For example, methods and materials for using one or more interventions (e.g., one or more pharmacological interventions) to treat obesity and/or obesity-related comorbidities in a mammal (e.g., a human) identified as being likely to respond to a particular intervention (e.g., a pharmacological intervention) are provided.