baber/WOPTO huggingface dataset:
Patent FI-932895-A0 (FI)
Inventor: WITTE ERNST-CHRISTIAN
IPC: C07D295/088
Filed: 1993-06-23
Abstract: PCT No. PCT/EP91/02456 Sec. 371 Date Jun. 21, 1993 Sec. 102(e) Date Jun. 21, 1993 PCT Filed Dec. 19, 1991 PCT Pub. No. WO92/11234 PCT Pub. Date Jul. 9, 1992.Compounds of the formula I     <IMAGE>  (I)  in which R1 signifies an aryl, aralkyl or an aralkenyl group, the aryl radical of which can, in each case, be substituted one or more times by halogen, cyano, alkyl, trifluoromethyl, alkoxy, alkylthio, trifluoromethoxy, hydroxyl or carboxyl, m a whole number from 1 to 3, n a whole number from 1 to 5, R2 hydrogen, an alkyl, aralkyl or acyl group, Q a bond or an oxygen atom, R3 hydrogen or a lower alkyl radical which is possibly terminally substituted by carboxyl or by a hydroxyl group and R4 hydrogen, a lower alkyl group with 1-4 C-atoms, which is possibly terminally substituted by carboxyl or hydroxyl, a possibly substituted phenyl, heteroaryl, cycloalkyl or acyl group or a group    <IMAGE>   in which R5 represents a straight-chained or branched alkyl chain with 1-4 C-atoms which is possibly terminally substituted by carboxyl, alkoxycarbonyl, aminocarbonyl, hydroxyl, mercapto, alkylthio or imidazolyl and Y a carboxyl, an alkoxycarbonyl, aminocarbonyl or cyano, formyl, hydroxymethyl, aminomethyl or ortho ester group, whereby R3 and R4 can also be component of a 5- or 6-membered saturated or unsaturated possibly substituted heterocycle with 1-4 heteroatoms which can be annellated with further ring compounds via one or more bonds, as well as their salts, esters and amides, processes for their preparation and medicaments with thromboxane-antagonistic action which contain these compounds.
Patent FI-933262-A0 (FI)
Inventor: PERSSON CHRISTER
IPC: A61M25/02
Filed: 1993-07-19
Abstract: PCT No. PCT/SE92/00030 Sec. 371 Date Jul. 20, 1993 Sec. 102(e) Date Jul. 20, 1993 PCT Filed Jan. 24, 1992 PCT Pub. No. WO92/12757 PCT Pub. Date Aug. 6, 1992.A vein catheter dressing comprising a supporting foil (1), an adhesive layer (2) on one side of the foil, a liquid-absorbent pad (3) placed centrally on the adhesive layer, the pad being considerably smaller than the supporting foil (1) and being preferably placed within or substantially within one-half of the supporting foil when the foil is divided transversely, and further comprises two release foils (8,9) over the adhesive layer and meeting over or in the vicinity of the pad (3), and a slit (6) which departs from one edge of the dressing and extends substantially up to the pad (3), optionally also through a part of the pad, wherein a window aperture is provided in the supporting foil and optionally also in the adhesive layer (2) in the vicinity of the pad on that side thereof which lies opposite the slit (6), this window aperture being covered with a layer of transparent material (5).
Patent FI-933902-A0 (FI)
Inventor: HEMMERLE HORST
IPC: C07F9/38
Filed: 1993-09-07
Abstract: Esters of cyclohexane derivatives of the formula I <IMAGE>  in which A-B, R<3>, R<4>, R<5>, Y and Z have the stated meanings, for use as inhibitors of the glucose-6-phosphatase system in the liver of mammals are described. The compounds are suitable for producing pharmaceutical products.
Patent FI-942003-A0 (FI)
Inventor: MUECK HAJO
IPC: B42D25/355
Filed: 1994-04-29
Abstract: The security paper material has a security strip (7) in a width of more than 2mm, embedded in the first paper layer (6) of a multi-layer paper structure, with openings in the paper surface for at least partial exposure of the strip on both sides. The first paper layer (6) is covered by at least one further paper layer (9), and they are bonded together. The second paper layer (9) has a thickness of 10-50% of the total thickness of the security paper (15), and pref. 20%. Also claimed is a mfg. process where the initial paper layer is formed conventionally, and the security strip is embedded in the paper while it sets into a paper material, with windows formed where the security strip is accessible. The security strip, with a width more than 2 mm, with a width selected for the holes formed on the side away from the rotary fourdrinier while giving a smooth and unbroken paper surface on the side of the paper towards the fourdrinier. At least one further paper layer is produced in parallel with the first stage, to be applied to the reverse side of the first paper layer, to be bonded together covering the openings in the first paper surface or give a defined shape. Similarly, a third paper layer is formed to cover the other side, to be followed by further finishing processes such as calendering, glue application, drying, etc.
Patent FI-944236-A0 (FI)
Inventor: GOLDBERG ARTHUR M
IPC: A61P25/06
Filed: 1994-09-13
Abstract: This invention relates to a method for treating classical migraine headaches. Pursuant to this method, a therapeutic amount of  beta -adrenergic-blocking agent is administered to a person suffering a migraine attack promptly upon onset of aura. The invention further relates to a method wherein the blocking agent is nasally administered.
Patent FI-945607-A0 (FI)
Inventor: MOREIRA NELSON COSTA
IPC: F27B3/14
Filed: 1994-11-28
Abstract: A drop in, and lift out, furnace lining assembly for use in a furnace shell of a metal refining vessel comprises (a) a lifting frame, having a base section, four lifting rods attached to the base section and a set of lifting cables attached to the lifting rods; and (b) a pre-cast and pre-fired refractory inner lining, and backup refractory/outer insulation lining, positioned and supported in the lifting frame movable into and out of the furnace shell as an integral unit by means of lifting equipment without moving the furnace shell from its operational position.
Patent FI-951046-A0 (FI)
Inventor: LAZARUS ROBERT A
IPC: C12N1/21
Filed: 1995-03-07
Abstract: Mutants of 2,5-diketo-D-gluconic acid reductase A, an enzyme used to produce 2-keto-L-gulonic acid, a precursor of ascorbic acid (vitamin C) are prepared by site-directed mutagenesis. These mutants have increased catalytic activity, increased expression levels, and/or enhanced temperature stability.
Patent FI-951593-A0 (FI)
Inventor: DENIS JEAN-NOEL
IPC: C07D305/14
Filed: 1995-04-04
Abstract: PCT No. PCT/FR93/00965 Sec. 371 Date Apr. 5, 1995 Sec. 102(e) Date Apr. 5, 1995 PCT Filed Oct. 4, 1993 PCT Pub. No. WO94/07876 PCT Pub. Date Apr. 14, 1994This invention relates to a method of preparing esters of baccatine III or 10-deacetylbaccatine III of formula (I) by esterification of protected baccatine III or 10-deacetylbaccatine III of formula (II) by means of an activated acid of formula (III). The esters of formula (I) can be used to prepare taxane derivatives having remarkable antileucemia and antitumor properties. In formulae (I), (II) and (III) Ar is an aryl radical, R1 is a hydrogen atom or an aryl radical or an R4-O-CO- radical (R4=alkenyl, alkynyl, optionally substituted alkyl, cycloalkyl, cycloalkynyl, bicycloalkyl, phenyl, heterocyclyle) and R2 is a hydrogen atom, and R3 stands for a hydroxy function protection grouping, or R1 is defined as above and R2 and R3 together form a 5 or 6 membered, saturated heterocyclic ring, G1 is an acetyl radical or a hydroxy function protection grouping, G2 is a hydroxy function protection grouping, and X is an acyl radical, aryl, radical or halogen atom.    <IMAGE>  (I)     <IMAGE>  (II)   <IMAGE>  (III)
Patent FI-955261-A0 (FI)
Inventor: CHESNUT ROBERT W
IPC: C07K14/705
Filed: 1995-11-02
Abstract: The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo. Both murine and humanized antibodies are provided.
Patent FI-970736-A0 (FI)
Inventor: FISCHER BARRY E
IPC: A24B3/18
Filed: 1997-02-21
Abstract: A tobacco expansion apparatus and method comprising a source of tower gas, an obloid transfer duct, in communication with the gas source, a tobacco feeder at a location along the obloid transport duct and a separator for recovering tobacco from the expansion apparatus. The tobacco feeder is adapted to introduce tobacco uniformly across the width of the obloid transfer duct. The apparatus improves the filling power of the processed tobacco and can be operated at higher production rates with less tobacco breakage, thereby improving tobacco yield.
Patent FI-973797-A0 (FI)
Inventor: BELLMANN GUENTHER
IPC: A61K9/00
Filed: 1997-09-26
Abstract: The invention relates to a sterile ophthalmic drop preparation, especially a gel preparation, which comprises a two-phase carrier liquid or gel basis comprising a liquid aqueous and a liquid hydrophobic phase.
Patent FI-980417-A0 (FI)
Inventor: HUKKANEN PENTTI
IPC: C09C3/08
Filed: 1998-02-24
Abstract: The invention relates to a process for the bleaching of a mineral pigment or a synthetic pigment, in which process the pigment to be bleached is contacted with a solution which contains peracetic acid in order to obtain a pigment with a raised degree of brightness.
Patent IL-75042-A0 (IL)
Title: 2,3-diamino-2,3-didesoxyhexose derivatives,their preparation and pharmaceutical compositions containing them
IPC: C07D207/40
Filed: 1985-04-29
Abstract: PCT No. PCT/EP85/00171 Sec. 371 Date Dec. 18, 1985 Sec. 102(e) Date Dec. 18, 1985 PCT Filed Apr. 17, 1985 PCT Pub. No. WO85/04881 PCT Pub. Date Nov. 7, 1985.Compounds of formula I   <IMAGE> I  wherein R2 and R3 are the same or different and each represent unsubstituted or substituted acyl, and (a) R1 represents lower alkyl, aralkyl or the phosphate, pyrophosphate, phosphorylethanolamine or pyrophosphorylethanolamine group, R4 represents the phosphate, pyrophosphate, phosphorylethanolamine or pyrophosphorylethanolamine group and one of R1 and R4 may additionally represent hydrogen and R5 represents hydrogen or a glycosyl radical or (b) R1 represents hydrogen, lower alkyl or aralkyl and R4 and R5 represent hydrogen, which compounds are indicated for use as pharmaceuticals, in particular as immunostimulants.
Patent IL-79926-A0 (IL)
Title: Superoxide dismutase
IPC: C07K14/00
Filed: 1986-09-02
Abstract: A superoxide dismutase originally found in extracellular body fluids and therefore termed extracellular superoxide dismutase (EC-SOD) is prepared by growing a cell line, preferably of mammalian origin, producing EC-SOD and recovering the EC-SOD secreted from the cells or by inserting a DNA sequence encoding EC-SOD into a suitable vector, introducing the recombinant vector into a host cell, growing the cell and recovering the EC-SOD produced. EC-SOD may be used for the prophylaxis or treatment of diseases or disorders associated with the presence or formation of superoxide radicals.
Patent IL-81334-A0 (IL)
Title: 3-(acylaminomethyl)imidazo(1,2-a)pyridine derivatives,their preparation and their application in therapy
IPC: A61K31/435
Filed: 1987-01-21
Abstract: Compounds of general formula (I) <IMAGE> in which R1 is hydrogen or an alkyl or benzyl group and R2 is an alkyl, alkenyl, phenyl or benzyl group, or else R1 and R2 form an aliphatic chain, each of X1, X2 and X3 is hydrogen or a halogen or an alkyl, methoxy, alkylthio, methylsulphonyl, trifluoromethyl, carboxyl, cyano, nitro, amino or aminocarbonyl group, and Y is hydrogen or a halogen or a methyl, trifluoromethyl, carboxyl, cyano, amino or aminocarbonyl group. Application in therapeutics.y
Patent IL-85509-A0 (IL)
Title: Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride and their production
IPC: A61K9/127
Filed: 1988-02-23
Abstract: Disclosed are large multivesicular liposomes containing biologically active substances, the multivesicular liposomes having defined size distribution, adjustable average size, adjustable internal chamber size and number, and having substantially higher encapsulation efficiency and substantially slower leakage rate of the biologically active substance than in the previous art. The process comprises dissolving a lipid component in volatile organic solvents, adding an immiscible aqueous component containing a hydrochloride and one or more biologically active substances to be encapsulated, making a water-in-oil emulsion from the two components, immersing the emulsion into a second aqueous component, dividing the emulsion into small solvent spherules which contain even smaller aqueous chambers, and then evaporating the solvents to give an aqueous suspension of multivesicular liposomes encapsulating biologically active substances.
Patent IL-85999-A0 (IL)
Title: Preparation of(2,2)-paracyclophane and derivatives thereof
IPC: C07C1/32
Filed: 1988-04-06
Abstract: Process for the preparation of (2,2)-paracyclophane or derivatives thereof by the Hofmann elimination of p-methyl-benzyl-trimethylammonium hydroxide or derivatives thereof, in an aqueous solution of an alkali metal hydroxide, wherein said elimination is carried out in the presence of a compound of the formula (I):      (R)m- A - (X)n      (I) wherein A represents an aromatic group, X an electron donor group, R hydrogen or an alkyl group containing from 1 to 4 carbon atoms, n is an integer comprised between 1 and 6 and m is zero or an integer comprised between 1 and a value such that the sum m+n be equal to the number of substituable positions in the aromatic group.
Patent IL-91770-A0 (IL)
Title: Drainage device
IPC: A61M1/00
Filed: 1989-09-25
Abstract: A drainage device (10), particularly adapted for use in medical procedures for draining fluids from a body cavity of a patient, incorporating a suction control chamber (32) dimensioned and configured to provide an enhanced air and liquid flow pattern within the chamber. The suction control chamber (32) might also include a baffle plate (60) for air and noise control. The drainage device (10) might further include a seal chamber (30) and an improved high negativity relief valve (74). The present invention also includes a device (100), having an integral sampling or injection port (116), for coupling tubing.
Patent IL-92261-A0 (IL)
Title: Device for connecting accessory parts to formwork panels
IPC: E04G7/26
Filed: 1989-11-09
Abstract: PCT No. PCT/DE89/00675 Sec. 371 Date May 13, 1991 Sec. 102(e) Date May 13, 1991 PCT Filed Oct. 23, 1989 PCT Pub. No. WO90/05226 PCT Pub. Date May 17, 1990.A device (1) serves for connecting accessory parts (2) to formwork panels, compensating members or suchlike formwork members having stiffening webs or stiffening profiles (3) on their side averted form the forming surface. The device (1) has an essentially U-shaped cross section, the U-arms (4) having fastening locations (5), preferably bores, for the accessory parts (2) such as booms, adjustable props, platform brackets or the like, and in the position of use the U-crosspiece (6) butting and being drawn fast against a stiffening profile (3) and above all against a cross web (3b) provided on this profile (3). At least one of the U-arms (4), preferably both U-arms (4), has an extension (7) passing over part of its length and beyond the U-crosspiece (6) on that side of the U-arms which faces the forming surface in the position of use, the extension being provided as protection against torsion and being adapted to be placed against the longitudinal side face (3a) of the stiffening profile ( 3) and against the transition from the rearward web (3b) to the longitudinal side face (3a). The U-crosspiece (6) of the device (1) has at least one recess or hole (8)-possibly even one open at the edge-for a fastening member to engage, preferably for the shank (9a) of a fastening member (9) to pass through. It is thereby possible for the device (1) to be anchored-in a torsion-proof position and in two orientations rotationally staggered through 90 DEG -to a stiffening profile (3), so that the forces and moments encountered can be transferred well (FIG. 1).
Patent IL-99444-A0 (IL)
Title: Apparatus and method for effecting dorsal vein ligation and tubular anastomosis and laparoscopic prostatectomy
IPC: A61B17/115
Filed: 1991-09-08
Abstract: A ligator assembly comprising a hollow, two-piece, bullet-shaped case dimensioned to be inserted in and through a body member, a pair of suture needles carried by the case, and a suture affixed to the needles. The case is provided with a pair of guide tubes for retaining the needles and guiding them out through a substantially transverse slot at the end of the case. A drive mechanism is also provided for remotely driving the needles longitudinally out of the case through the slot. The case is selectively connectable to an elongated tubular operator for placement of the ligator assembly. Apparatus for effecting an anastomosis comprises female and male connector components usable with an operator, an inflatable anvil assembly, and a connector actuator and which include mutually facing clamping surfaces for clamping generally annular tissue portions of the first and second body members together. The female connector component includes a plurality of resilient legs having bores extending therethrough. The legs are movable between a retracted position when the inflatable anvil is contracted and a distended position when the anvil is expanded. The male connector component is received by the connector actuator and includes a plurality of posts for piercing the annular tissue portions in response to actuation of the connector actuator and for matingly engaging the bores in the female connector component when the legs are in the distended position.
Patent AU-PQ616300-A0 (AU)
Title: A toy
IPC: A63H17/00
Filed: 2000-03-10
Abstract: The present invention creates a toy (10,60) comprising a plurality of removable members (20,22,24,30,66,68,70), each member having a predetermined shape, such that the members, when assembled in a predetermined order, form the outer shape of the toy, each member also having a plurality of removable elements (28,52,54,92,94,96) of a predetermined shape that are insertable into a correspondingly shaped void (40,42,44,46,48,50,90) in the member, whereby the toy may be assembled with or without the elements being within their corresponding members.
Patent FI-20031699-A0 (FI)
Inventor: KINNUNEN HANNU
IPC: A61B5/11
Filed: 2003-11-21
Abstract: An arrangement, method and computer program for determining the physical activity level of a human being. The arrangement comprises a movement sensor (114) to be attached to an upper limb of the human being for measuring upper limb movements, a processing unit (100) connected to the movement sensor (114) for filtering upper limb movements following one another more frequently than a predetermined threshold period from upper limb movements during a determination period, for forming the number of upper limb movements during the determination period from the filtered upper limb movements during the determination period, and for determining the physical activity level on the basis of the number of upper limb movements during the determination period formed from the filtered upper limb movements during the determination period. <IMAGE>
Patent FI-20075838-A0 (FI)
Inventor: KANGAS JANI
Filed: 2007-11-26
Abstract: The present invention relates to a frequency converter (1) comprising a memory (M1) for storing data; a controller (8) for controlling the operation of the frequency converter by utilizing data (DATA1) stored in the memory (M1); and an interface (10) for connecting the frequency converter to other frequency converters. For efficient and simple backuping and restoration of the backup copy, the frequency converter comprises a backup application (9) for backuping the data (DATA1) stored in the memory (M1) of the frequency converter by retrieving data stored in the memory of the frequency converter and by transmitting the data retrieved over the interface (10) to at least one other frequency converter for storage in a memory (M2, M3) of said at least one other frequency converter; and maintains a backup copy (DATA2, DATA5) of at least one other frequency converter by storing the data received over the interface (10) from said at least one other frequency converter in the memory (M2, M3).
Patent IL-105797-A0 (IL)
Title: Cyclopentane-and-pentene-beta-amino acids,their preparation and pharmaceutical compositions containing them
IPC: A61K31/16
Filed: 1993-05-25
Abstract: Cyclopentane- and -pentene- beta -amino acids of the general formula (I) <IMAGE>  in which   A, B, D, E, G, L, M and T are identical or different and, with the proviso that at least one of the abovementioned substituents is H, represents hydrogen, halogen, benzyl, hydroxyl or optionally substituted alkyl with up to 8 carbon atoms, or in each case B and D, E and G or L and M together represent a radical of the formula <IMAGE>     or =N-OH, or E and G and/or B and D together represent the radical of the formula =O or =S, or B, D, E and G or E, G, L and M each together form a radical of the formula <IMAGE> in which D' and G' have the abovementioned meaning of D and G, but do not both denote hydrogen and G and L have the abovementioned meaning   V is an oxygen or sulphur atom or the -NH group, R<1> is hydrogen, optionally substituted alkyl or optionally substituted phenyl or, if V is the -NH group, is the group of the formula -SO2R<8>, R<2> is hydrogen, an amino protective group customary in peptide chemistry, optionally substituted alkyl with up to 8 carbon atoms, acyl with up to 8 carbon atoms, optionally substituted benzoyl, a group of the formula -SO2R<8> or an amino acid residue of the formula   <IMAGE>   R<3> is hydrogen or optionally phenyl-substituted alkyl with up to 8 carbon atoms, or R<2> and R<3> together represent the radical of the formula =CHR<14>, process for their preparation and their use as pharmaceuticals, especially antimycotic pharmaceuticals, are described.
Patent IL-109994-A0 (IL)
Title: Hybrid alternator with voltage regulator
IPC: H02K16/02
Filed: 1994-06-13
Abstract: A hybrid alternator includes a stator 10 and a rotor 20, with the rotor 20 having longitudinally separate wound field 24 and permanent magnet 38 rotor portions. A rotor excitation circuit applies a forward polarity to the wound field rotor portion 24 to increase output in a boosting mode at low RPMs and a reverse polarity to decrease output at high RPMs in a bucking mode to maintain a constant voltage output. Alternative embodiments combine a magnetic flux concentrating design for efficient low speed operation with integral strength for high speed capability. Dual voltage output is provided either through dual stator windings or through a voltage converter circuit. Single voltage output is provided using only one stator winding. A three state voltage regulator allows voltage regulation without inducing reverse currents onto the power bus in the lightly loaded or no battery conditions. The regulator has automatic interlocking to automatically turn on and off without risking <IMAGE>
Patent IL-122764-A0 (IL)
Title: A tubular product and an extrusion apparatus and method
IPC: B29C48/09
Filed: 1996-06-20
Abstract: The invention relates to a pipe made of several different materials. The innermost layer is a plastic layer (15), outside of which there is an inner electrode layer (32c). Outside of the latter there is an insulating layer (32b), outside of which there is an outer electrode layer (32a).