baber/WOPTO huggingface dataset:
Patent DE-69833858-D1 (DE)
Inventor: SEKO TAKUYA
IPC: C07D417/12
Filed: 1998-07-03
Granted: 2006-05-11
Abstract: A compound of the formula (I): <CHEM> Äwherein R<1> is (substituted) alkyl, alkoxy, phenyl, hetero ring etc.; A is bond, CO, SO2; R<2> is H, (substituted) alkyl etc.; D is alkylene etc.; E is COO, OCO, O, S, SO, SO2 etc.; R<3> is (substituted) alkyl, carbocyclic ring, hetero ring; J is O, NR<16> (R<16> is H, substituted alkyl); R<4> is (substituted) alkyl, carbocyclic ring, hetero ring.Ü or non-toxic salt thereof, and an N-type calcium channel blocker comprising it as an active ingredient.   The compounds of the formula (I) possess an inhibitory action on N-type calcium channel, so they are useful as agent for the prevention and/or treatment of cerebral infarct, transient ischemic attack, encephalomyelopathy after cardiac operation, spinal angiopathy, hypertension with stress, neurosis or epilepsy etc. or agent for the treatment of pain.
Patent DE-69907294-D1 (DE)
Inventor: COLLINS HAMILTON P II
IPC: A61F11/00
Filed: 1999-02-16
Granted: 2003-06-05
Abstract: An external ear canal drying apparatus 10 comprising a hinged clam shell style housing 11 containing a forced air generating unit 12 having a blower motor 25 and a heating element 26 operatively associated with an air intake and exhaust conduit 22 that has an exhaust port nozzle 24 dimensioned to receive a conduit 32 centrally disposed within a tapered resilient housing 31 having return air passageways 39 that surround the central conduit for introducing forced hot air into and out of the auditory canal 100. <IMAGE>
Patent DE-69908984-D1 (DE)
Inventor: ABBOTT RONALD
IPC: B60C17/00
Filed: 1999-04-12
Granted: 2003-07-24
Abstract: A pneumatic tire (10) incorporates a plurality of parallel-aligned, tread-stiffening support members (23) typically disposed laterally between the tread (12) and the ply structure (16). The support members (23) inhibit lateral and circumferential tread lift during runflat operation. Support members (23) can each be a monolithic rib (22) made of a fiber reinforced plastic material. An alternative layered rib (24) has two outer layers (40, 44) of a fiber reinforced plastic material while the central layer (42) is an elastomer.
Patent DE-69911648-D1 (DE)
Inventor: SMOLEJ ANTON
IPC: C22C21/00
Filed: 1999-12-20
Granted: 2003-10-30
Abstract: A free-cutting aluminum alloy without lead as an alloy element, containing: (a) as alloy elements: 0.5 to 1.0 wt. % Mn; 0.4 to 1.8 wt. % Mg; 3.3 to 4.6 wt. % Cu; 0.4 to 1.9 wt. % Sn; 0 to 0.1 wt. % Cr; 0 to 0.2 wt. % Ti; (b) as impurities: up to 0.8 wt. % Si; up to 0.7 wt. % Fe; up to 0.8 wt. % Zn; up to 0.1 wt. % Pb; up to 0.1 wt. % Bi; up to 0.3 wt. % total of other impurities; and (c) the balance being substantially aluminum. The process includes the steps of semicontinuously casting the above alloy composition followed by homogenization annealing, cooling, heating to a working temperature for extrusion, extruding at a maximum temperature of 380° C., followed by press-quenching and aging. The aging may be a natural aging or an artificial aging. A cold working step and/or a tension straightening step also may be conducted after the press-quenching step. The extruding step includes indirectly extruding.
Patent DE-69924007-D1 (DE)
Inventor: JANSEN U
IPC: C12Q1/6897
Filed: 1999-12-20
Granted: 2005-04-07
Abstract: Pseudovirions, comprised of a papilloma virus-like particle (VLP) joined to a reporter gene construct are described. The pseudovirions can be used in assays to detect the presence of anti-VLP neutralizing antibodies. Also described are processes for making the pseudovirions.
Patent DE-69925895-D1 (DE)
Inventor: CHUJO YOSHIKI
IPC: C08F8/12
Filed: 1999-09-22
Granted: 2005-07-28
Abstract: A process for producing vinyl alcohol polymer composition comprises subjecting a solution containing a metal alkoxide or its oligomer, a vinyl carboxylate polymer, and an organic solvent to polycondensation and saponification reactions while removing low-boiling point ingredients including organic solvents. The polycondensation reaction of the alkoxide or its oligomer and the saponification of the vinyl carboxylate polymer are simultaneously conducted in the same reaction system. The amount of the alkoxide or oligomer used in the process is controlled to be 0.01 - 100 mol based on the total amount of the metallic atoms contained in the alkoxides or oligomers per 100 mol of the acyl groups originating from the vinyl carboxylate.
Patent DE-69927582-D1 (DE)
Inventor: FALCK R
IPC: A61K38/00
Filed: 1999-05-14
Granted: 2006-02-16
Abstract: The present invention includes 16-HETE analogs which are agonists and antagonists of 16-HETE. The compositions may be formulated in pharmaceutically acceptable formulations. The invention also includes methods and products for inhibiting neutrophil adhesion and neutrophil aggregation using the 16-HETE agonists. One method of the invention involves the administration of a 16-HETE agonist in combination with a thrombolytic agent to a patient suffering from, thromboembolic stroke.
Patent DE-69928084-D1 (DE)
Inventor: SKLAR ERIC
IPC: B01L3/00
Filed: 1999-02-25
Granted: 2005-12-08
Abstract: The description describes a test sample preparation device comprising a housing, a filter assembly disposed over an opening in the housing and including a plurality of wells, a sampler tray removably disposed in the housing, and a plurality of vials removably coupled to the sampler tray and being in liquid receiving relationship with the wells. A filter assembly is also disclosed and which comprises a cover defining an impervious wall and plurality of wells formed in the wall, each wall having first and second open ends, the second open end of the well comprising a tubular protrusion. A housing is also disclosed and comprises a generally cylindrical body, a vacuum channel providing fluid communication between the interior and the exterior of the cylindrical body, and a key mechanism including a post having first and second ends, the key mechanism being arranged to orient a sampler tray and vials with respect to the housing. A method for simultaneously preparing multiple test samples for automated liquid chromatography and a method for automated liquid chromatography are also disclosed and comprise depositing test samples into a plurality of wells, simultaneously passing the test samples through porous media disposed in the wells, and depositing the filter test samples directly into vials removably coupled to a sampler tray.
Patent DE-69930873-D1 (DE)
Inventor: HOWARD D
IPC: C12N5/10
Filed: 1999-12-16
Granted: 2006-05-24
Abstract: The present invention relates to DNA molecules encoding splice variants of the melanocortin-1 receptor (MC-R1) protein belonging to the rhodopsin sub-family of G-protein coupled receptors, recombinant vectors comprising DNA molecules encoding MC-R1B protein, recombinant host cells which contain a recombinant vector encoding MC-R1B, the human MC-R1B protein encoded by the DNA molecule, and methods of identifying selective agonists and antagonists of MC-R1B proteins disclosed throughout this specification.
Patent DE-69940028-D1 (DE)
Inventor: KOYAMA HIROSHI
IPC: B41M5/52
Filed: 1999-10-27
Granted: 2009-01-15
Abstract: A support which comprises a base layer (B) composed of a biaxially stretched film of a thermoplastic resin containing an inorganic fine powder; and a surface layer (A) provided at least on one side of such base layer (B), which is composed of a biaxially stretched film of a thermoplastic resin having a three dimensional center plane average roughness of 0.3  mu m or below and a 60 degrees surface glossiness of 80% or above is disclosed. A thermal transfer image-recording material using such support can produce a clear image having an excellent glossiness and no external waviness. <IMAGE>
Patent DE-69941166-D1 (DE)
Inventor: BROADFIELD LAIRD
IPC: A61J3/00
Filed: 1999-05-29
Granted: 2009-09-03
Abstract: A system and apparatus are described in which modular receptacles are filled and transported to automated dispensing machines for later retrieval and distribution. A system of the present invention includes the loading, refilling, and replacement of the modular receptacles at various stages in the process of the invention. The present invention results in a more efficient and easier to manage system for distribution of such items as medical supplies and drugs.
Patent DE-69942975-D1 (DE)
Inventor: RICHARDS WILLIAM
IPC: G01N1/36
Filed: 1999-02-26
Granted: 2011-01-05
Abstract: Aspirating and dispensing of reagents is accomplished using a probe (119) having an outlet (144) connected via tubing (142) to a syringue pump. The probe (119) has an o-ring (134) for sealing against a vial insert (150) coupled to a dip tube (156) in the reagent vial during aspiration. The probe (119) is then moved to a dispense and washing station that seals against the o-ring (134), and the reagent is dispensed and the probe washed.
Patent DE-502004005647-D1 (DE)
IPC: F16B5/02
Filed: 2004-04-23
Abstract: The fastening unit for the fastening of objects to a bearing structure section of concrete, brick or suchlike, has at least one fastening element by which a L-shaped attachment component (10) is connected to the bearing structure section. The attachment component is dimensioned in such a way that with individual or combined loading in at least two directions (X,Y,Z) the elastic load-bearing capacity of the attachment component is at least sectionally exceeded before the maximum load-bearing capacity of one fastening element or all the fastening elements is reached. Independent claims are also included for the following: (A) an attachment component for the aforesaid fastening unit; and (B) a connection between a bearing structure section and at least one additional bearing structure section, including the proposed fastening unit.
Patent DE-502004005901-D1 (DE)
Inventor: LENHART MANFRED
IPC: F04B15/02
Filed: 2004-09-15
Abstract: In a two-cylinder slurry pump for the continuous feeding of, in particular, concrete, in which pump two feed cylinders remove the high-viscosity material from a pre-charging tank and deliver it to a feed line, a diverter valve is provided with a cross-section that narrows from an inlet opening assigned to the cylinders to a discharge opening assigned to the feed line, which diverter valve connects, in any position, at least one feed cylinder, over its entire cross-section, to the feed line, a support arrangement (20) and a plate cam (15) securely connected thereto being assigned in accordance with the invention to the diverter valve (11) on its side facing towards the cylinders (3, 5). The plate cam (15) comprises not only the inlet opening (21) of the diverter valve (11) but also an intake opening (23), which is arranged at sufficient distance from the inlet opening (21) to cover an opening of one of the feed cylinders (3, 5) completely. Additionally, a process for controlling this continuous-feed slurry pump is described.
Patent DE-502004007795-D1 (DE)
Inventor: HAAKS STEFAN
IPC: G05B23/02
Filed: 2004-09-24
Abstract: The invention relates to a method and a device for determining the causes of malfunctions and performance limits in installations. It is difficult to determine the causes of disturbances and/or performance-limiting factors in complex installations. The inventive method allows malfunctions in an installation to be eliminated and/or the performance thereof to be increased in a lasting manner and with relatively little effort. Said method comprises the following steps: data is provided on causes of malfunctions and performance limits in a plurality of installations; a questionnaire regarding said causes is created from said data; replies relating to the questions of the questionnaire are solicited from employees working in the installation that is to be diagnosed; and the causes of malfunctions and performance limits of the installation that is to be diagnosed are determined by evaluating the replies supplied by the employees regarding the questions of the questionnaire.
Patent DE-502004010303-D1 (DE)
Inventor: HORSTMANN MICHAEL
IPC: A61K31/428
Filed: 2004-08-14
Abstract: The transdermal pharmaceutical preparations for the treatment of Parkinson's disease contain a combination of at least two active substances selected from the following groups of active substances: dopamine agonists and L-dopa, monoamine oxidase inhibitors, anticholinergics, NMDA-receptor antagonists, sympathomimetics; at least two of the said active substances being members of different active substance groups.
Patent DE-502004010685-D1 (DE)
Inventor: BUEHLER ERICH
IPC: D03C13/00
Filed: 2004-11-05
Abstract: The invention relates to a thread control device for a textile machine, in particular, for a shedding device, with at least one thread guide body ( 31 ) which may be displaced in one displacement direction by means of a positive drive ( 35 ) and in the opposite direction by means of a non-positive, pneumnatic return device ( 36 ). Me return device ( 36 ) thus comprises a cylinder/piston unit ( 64,54 ), the cylinder chamber of which ( 52 ) is connected to a compressed gas source ( 60 ) by means of a valve ( 56 ). An improvement in control is achieved when the valve ( 56 ) comprises a first valve seat ( 72 ) connected to the cylinder chamber ( 52 ) and a second valve seat ( 76 ), between which a valve body ( 82 ), provided with at least one throttle point ( 80 ), may be displaced, pre-tensioned in the rest position by means of a spring ( 84 ) against the first valve seat ( 72 ), in which the throttle point ( 80 ) is ineffective and the valve body ( 82 ) blocks the communication with the compressed gas source ( 60 ) when the valve body ( 82 ) is in contact with the second valve seat ( 76 ).
Patent DE-502004011252-D1 (DE)
Inventor: BADER AUGUSTINUS
IPC: A61K35/407
Filed: 2004-12-30
Abstract: Use of hematopoietic growth factors (I), especially erythropoietin (EPO), thrombopoietin (TPO) or their derivatives, analogs and fragments, to prepare a composition for structural regeneration of tissue, is new. Independent claims are also included for the following: (1) similar use of an EPO-inducing factor (II); (2) carrier structure containing at least one (I) or (II); (3) preparing the structure of (2); and (4) composition comprising cells (A) that have been pretreated, in vitro, with (I). ACTIVITY : Hepatotropic; Osteopathic; Cardiant; Ophthalmological; Uropathic; Antiinflammatory; Antiulcer; Vulnerary; Neuroprotective. Part of the liver was removed from pigs, then the animals (a) given no treatment; (b) treated locally with 10 4> units EPO and a fibrin glue; or (c) treated systemically with 10 4> units EPO on days 0, 3, 7 and 11. After 14 days, the mean liver volume (ml) was (a) 892; (b) 894 and (c) 1073, and liver weight (g) was (a) 1001; (b) 1027 and (c) 1249; where these results for (c) are statistically significant at p less than 0.05. MECHANISM OF ACTION : Promoting regrowth of tissue.
Patent DE-502005001125-D1 (DE)
Inventor: LAWRENCE JEREMY
IPC: H01M8/06
Filed: 2005-06-09
Abstract: The system has a high temperature fuel cell (HTFC) stack (1) with current diverters (5) that are connected to a low temperature connecting unit (10) for current delivery. The current diverters are in thermal contact with a reformer and an afterburner (6) between the high temperature fuel cell stack and the low temperature connecting unit. A heat exchanger preheats an air supplied to the HTFC.
Patent DE-502005005054-D1 (DE)
Inventor: HIRTH THOMAS
IPC: C07C29/141
Filed: 2005-12-07
Abstract: Disclosed is a method for producing polyalcohols in the form of sugar alcohols from the group comprising sorbitol and mannitol and other optional C2 to C6 polyols. According to said method, a monosaccharide, disaccharide, oligosaccharide, or polysaccharide containing at least one glucose unit and/or at least one fructose unit is continuously reacted with hydrogen at an elevated temperature and at a great pressure in an aqueous phase in the presence of a hydrogenating catalyst based on ruthenium or ruthenium oxide so as to obtain the inventive polyalcohols. The minimum temperature is set at 100° C. while the minimum pressure is set at 150 bar and the maximum dwell time of the reactants during catalytic hydrogenation is set at 600 s. The inventive method is particularly suitable for producing the sugar alcohols sorbitol and/or mannitol or C2 to C6 polyols from glucose, fructose, or disaccharides, oligosaccharides, or polysaccharides containing glucose units or fructose units, especially saccharose, practically all the used saccharides being reacted without turning into caramel. Furthermore, the yield of said sugar alcohols or C2 to C6 polyols is exceptionally high while the selectivity for the desired products can be varied in a simple manner within broad boundaries.
Patent DE-502005005308-D1 (DE)
Inventor: PFEILER LUDWIG
IPC: B62D53/06
Filed: 2005-07-26
Abstract: Vehicle (1) comprises a chassis (5) with coaxially arranged wheels (8a) positioned on an axle (9) on both sides of a telescopic support consisting of a connecting rod (6) and a receiving sleeve (7). The axle has a right-angled bend (10) arranged around the telescopic support. Preferred Features: The bend is arranged the upper side of the telescopic support.
Patent DE-502005005429-D1 (DE)
Inventor: REBER WOLFGANG
IPC: B60R16/02
Filed: 2005-12-19
Abstract: A cassette (K) comprises rotor and stator for delimiting a circular accommodating area to accommodate flat ribbon cable (FRC) (10). An intermediate base fitted on a cylindrical hub of rotor, runs parallel to cover face and base of accommodating area. The intermediate base divides the accommodating area based on the height or width of the cable to be inserted.
Patent DE-502005008341-D1 (DE)
Inventor: HEIM JENS
IPC: F16C33/80
Filed: 2005-08-12
Abstract: The invention relates to a wheel bearing arrangement which enables a hub to be mounted in at least one non-rotating external ring such that it can rotate about the rotational axis of the hub. The wheel bearing arrangement comprises at least one sealing arrangement and one encoder and the sealing arrangement is secured to the hub side on the side of the wheel bearing arrangement whereon a radial flange extends in a radial manner from the hub. The encoder is actively connected to the sealing arrangement.
Patent DE-502005008689-D1 (DE)
Inventor: DESEYNE JOOST
IPC: D03C9/06
Filed: 2005-07-13
Abstract: A heald frame includes at least one frame part (10, 14) at least one heald carrying rod (16). A multitude of projections (25, 26), which are arranged one behind the other while being situated essentially in a row, are formed from the heald carrying rod (16) while projecting therefrom by means of plastic deformation and are held inside a recess (28) or the like of the frame part (10, 14).
Patent DE-502005009836-D1 (DE)
Inventor: GEISLER AXEL
IPC: B23K26/20
Filed: 2005-10-05
Abstract: A seat structure includes a frame having a plurality of parts having respective joining surfaces. Two respective joining surfaces, which belong to two respective different parts, are joined to one another by laser-welding. A method of forming a seat frame having a plurality of parts includes the steps of positioning the parts in a fixture, fixing the position of the parts relative to one another and laser-welding the parts to form the seat frame.
Patent DE-502006000085-D1 (DE)
Inventor: SUESSENBACH RAINER
IPC: F16B19/00
Filed: 2006-03-15
Abstract: The blind rivet for a screw connection between a carrier member (4) and an accessory (6) comprises an elastic outer component (10) with a foldable section (34) transformable into a bead (70) by an axially slidable, threaded metal inner sleeve (12).
Patent DE-502006001826-D1 (DE)
Inventor: KUEHN TORSTEN
IPC: A61K9/48
Filed: 2006-01-06
Abstract: The present invention relates to capsules for housing pharmaceutical preparations for powder inhalers with increased medicinal product safety and capsules for pharmaceutical preparations for powder inhalers with improved adaption to use in powder inhalers. The capsules consist of non-water-soluble, hydrophobic plastics, which themselves do not substantially influence the pharmaceutical quality of the contents, but improve the usability of the filled capsules in respect of their operation, the period of use and/or the geographical location of their use and are advantageous in various steps from manufacture to use.
Patent DE-502006002711-D1 (DE)
Inventor: NEUBERT WOLFGANG J
IPC: A61K48/00
Filed: 2006-02-10
Abstract: Recombinant negative-strand RNA virus (I) comprises a viral genome with a mutation in the N, L or P gene that results in loss of replication capability without loss of transcription capability. Independent claims are also included for: (1) nucleocapsid (II) of (I); (2) genome (III) of (I); (3) DNA molecule (IV) coding for the genome or antigenome of (I); (4) cell (V) containing (I), (III) or (IV); (5) producing (I) by providing a cell transfected with a DNA molecule coding for (I) and optionally a heterologous gene product, and culturing the cell under conditions suitable for transcription of the DNA molecule; (6) multiplying (I) by providing a cell infected with (I) and culturing the cell under conditions suitable for multiplication of (I); (7) pharmacuetical composition comprising (I), (II) or (III); (8) use of a cell (VI) that stably expresses the N, L or P protein of a negative-strand RNA virus in a constitutive or inducible manner for producing or multiplying (I) (II) or (III). ACTIVITY : Virucide. MECHANISM OF ACTION : Vaccine; Ribozyme; Antisense oligonucleotide inhibitor; RNAi; RNA interference.
Patent DE-502007000016-D1 (DE)
Inventor: WIEDMANN FERDINAND
IPC: F16C33/44
Filed: 2007-03-06
Abstract: The method involves installing strip materials on metal base with a lower surface and an upper surface. The installation of a sheet is on the base of a coating compound for reducing the friction coefficient. A sheet of an adhesive supplying material, in which adhesive supplying material and coating compound are sintered at a half finished product. The metal plastic hybrid strip is processed in the form of a rolling bearing cage. The surface side of the rolling bearing which has the coating is so arranged that it faces the roller bearing to be guided and to be supported.
Patent DE-502007001331-D1 (DE)
Inventor: THEISS STEFFEN
IPC: B65D73/00
Filed: 2007-04-26
Abstract: The package (3) has a projection enclosed around an element e.g. plaster roller, and a surface element (1) with an opening. Another surface element is formed as one-piece and has a holding section partly extending over the opening, where the holding section has a tearing edge (11). The surface element has connecting sections (18, 19) that connect attachment sections (8, 9) of the element (1) and the holding section with each other. The sections (18, 19) run bendingly to the plane and the holding section, and the edge runs parallel to the plane and the element (1).
Patent DE-502007004817-D1 (DE)
Inventor: MAYER F E
IPC: E05C17/54
Filed: 2007-10-01
Abstract: Disclosed is a door and/or window stopper comprising an outer contour that extends into a tip (25) and an inner hollow space (10) which, preferably, substantially matches said contour. As an external part (2), the outer edge of the stopper is made of rubber or a flexible, rubber-type thermoplastic material that has a relatively high coefficient of friction. A clip-type internal part (4) that is provided with two arms (12, 14) and has greater flexural rigidity than the external part (2) is disposed within the external part (2). In order to further develop said door and/or window stopper in such a way that the production is simplified, less material is used, and the weight is reduced, the wall thickness of at least one of the arms (12, 14) of the internal part (4) decreases towards the tip (24) such that the wall thickness (20) of the internal part (4) and/or the arm (12, 14) thereof is greater in the end region (28) than the wall thickness (22) in the tip (6) region of the internal part (4).