baber/WOPTO huggingface dataset:
Patent CA-2965256-A1 (CA)
Title: Novel pharmaceutical formulation
Inventor: CAVATUR RAGHU
IPC: A61K9/00
Filed: 2015-10-21
Abstract: The present invention is directed to a pharmaceutical composition comprising a pharmaceutically effective amount of guaifenesin, naproxen and at least one further active which is selected to be an antitussive, a decongestant or an antihistamine.
Patent CA-2965495-A1 (CA)
Inventor: SHEN YING
IPC: C12N15/90
Filed: 2015-10-21
Abstract: Expression-enhancing nucleotide sequences for eukaryotic expressions systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Genomic integration sites providing enhanced expression and methods of use thereof are provided for expression of a gene of interest in a eukaryotic cell. Chromosomal loci, sequences, and vectors are provided for enhanced and stable expression of genes in eukaryotic cells.
Patent CA-2966603-A1 (CA)
Inventor: KAPUR RAVI
IPC: C12M1/12
Filed: 2015-11-03
Abstract: Extracting and concentrating particles from a first fluid sample includes: providing the first fluid sample to a fluid exchange module of a microfluidic device, providing a second fluid sample to the fluid exchange module, in which the first fluid sample and the second fluid sample are provided under conditions such that particle-free portions of the first fluid sample are shifted, and an inertial lift force causes the particles in the first fluid sample to cross streamlines and transfer into the second fluid sample; passing the second fluid sample containing the transferred particles to a particle concentration module under conditions such that particle-free portions of the second fluid sample are shifted, and such that the particles within the second fluid sample are focused to a streamline within the particle concentration module.
Patent CA-2966778-A1 (CA)
Inventor: POWELL CHRISTIN
IPC: C07D339/06
Filed: 2015-11-03
Abstract: Provided are compositions, comprising a neolignan, ectoin, and a molecule of Formula I: wherein R1, R2 and R3 are independently H, methyl, ethyl, propyl, or isopropyl; wherein X is S or O. In some cases, the molecule of Formula I is ergothioneine (EGT). In some cases, the at least one neolignan is honokiol or a derivative thereof. Honokiol may be provided in the form of magnolia bark extract. Methods of making and using these compositions are also provided.
Patent CA-2968051-A1 (CA)
Inventor: LIGATTI JARRED ADAM
IPC: H04L9/32
Filed: 2015-04-22
Abstract: A system and method of authentication using an authenticator computing device and at least two registered user devices is described. In operation, the authenticator computing device receives a request to access a resource from one of a plurality of user devices registered to a user. The authenticator computing device generates an authentication challenge in response to the request and the authentication challenge is then transmitted to a subset of the plurality of user devices. One or more of the user devices then subsequently generates and transmits a response to the authentication challenge to the authenticator computing device. The authenticator computing device then determines whether the responses received from the one or more user devices in the subset constitutes a valid response and then grants one or more of the user devices access to the resource if the responses received from the user devices constitutes a valid response to the authentication challenge.
Patent CA-2968782-A1 (CA)
Inventor: ANESI ANDREA
IPC: B21B31/02
Filed: 2017-05-29
Abstract: A roller cage for a profiling line, comprising: a support frame (F1); a first motor equipped with a first substantially horizontal spindle (12) that projects in a cantilever fashion externally to a shoulder (S1) of the support frame (F1) into an operating space of the line; a first transverse roller (13), assembled directly on the first spindle (12); a movable frame (F2), with which an upright first roller (33) is associated, rotating about a first shaft (32) which projects in a cantilever fashion from the movable frame (F2); the movable frame (F2) is movable between an operating position, in which the first shaft (32) assumes a substantially vertical position, and a non-operating position, in which the first shaft (32) assumes a substantially horizontal position and is facing the same way as the first spindle (12), towards the operating space of the line.
Patent CA-2976568-A1 (CA)
Inventor: LIF FU YU
IPC: A61B5/366
Filed: 2017-08-16
Abstract: Des méthodes et des systèmes dutilisation de transformée en ondelettes dans une architecture à double voie pour traiter les signaux ECG des patients et les signaux ECG de référence de sujets étudiés antérieurement pour évaluer la santé cardiovasculaire du patient sont présentés. Larchitecture à double voie exécute une transformée en ondelettes sur les signaux ECG des patients et les signaux de référence pour extraire et analyser des caractéristiques de signal du domaine temporel en 2 dimensions des signaux ECG et pour bâtir et analyser un modèle en 3 dimensions de linformation du domaine de fréquence et du domaine temporel des signaux ECG. Les caractéristiques des signaux ECG des patients et des signaux ECG de référence peuvent être comparées et utilisées pour identifier une maladie cardiovasculaire du patient et pour recommander des tests de suivi. Les résultats de la comparaison peuvent également être utilisés pour configurer le dispositif ECG utilisé pour acquérir les signaux ECG du patient ou pour optimiser les paramètres de lanalyse 2D/3D.
Patent CA-2976906-A1 (CA)
Inventor: ZEIFMAN MICHAEL
IPC: E04B1/76
Filed: 2017-08-21
Abstract: Systems and methods for characterization of retrofit opportunities are described. The methods may comprise computing, using at least one computing device disposed remote from a building and based at least in part on heating, ventilation and air conditioning (HVAC) runtime data associated with the building, one or more thermal characteristics of the building. In some embodiments, a model-predicted indoor temperature may be fitted against thermal data measured by a thermostat at the building. The thermal characteristic of the building may comprise a thermal insulation, an air leakage rate and/or an HVAC efficiency. The method may be used to determine, using the at least one computing device, suitability of the building for a retrofit opportunity to improve energy efficiency of the building. Determining the suitability may comprise evaluating the one or more thermal characteristics. The HVAC runtime data may be computed based on data received from a thermostat or a meter, such as an electric or a gas meter.
Patent CA-2980488-A1 (CA)
Inventor: ECKELT JOHN
IPC: A61K47/10
Filed: 2016-03-21
Abstract: The present invention relates to a polymer solution for use as a rheological blood substitute. The rheological blood replacement solution comprises in its basic composition a water-soluble cellulose polymer with a molecular weight of 100 kDa or greater, polyethylene oxide and a solvent. The rheological blood replacement solution of the invention can be used in a variety of applications, e.g. as blood substitute, calibration agent or reference agent. The blood replacement solution is based on a polymer solution, which can also be used as pharmaceutical composition, e.g. for the prevention or treatment of haemorrhage or shock-related disorders.
Patent CA-2981282-A1 (CA)
Title: Wastewater denitrification method utilizing recycling of nitrified treatment effluent
Inventor: HILDEBRAND MARTIN
IPC: C02F3/30
Filed: 2017-10-03
Abstract: Described herein is a wastewater treatment process comprising an anoxic zone upstream of an attached growth reactor wherein a portion of nitrified waste from the attached growth reactor is recycled to a point in the treatment process that is upstream of at least part of the anoxic zone rather than being released from the system. As a result, the influent wastewater and the recycled effluent mix together and are nitrified and denitrified as they progress through the waste treatment system.  The key aspect of this process is that the nitrate-rich, effluent water is returned to the anoxic reactor for (additional) denitrification of the wastewater.
Patent CA-2985455-A1 (CA)
Title: Vacuum low-temperature cooker
Inventor: LEE KYUL-JOO
IPC: B65B65/00
Filed: 2016-05-10
Abstract: A vacuum low-temperature cooker according to the present invention comprises: a main body having a heating unit which is immersed in fluid received in an accommodation tub and heats the fluid; a vacuum packing unit which is connected to the main body and vacuum-seals packing paper; and a control unit which is installed in the main body or the vacuum packing unit, and is electrically connected to the heating unit and the vacuum packing unit so as to control the heating unit and the vacuum packing unit.
Patent CA-2986622-A1 (CA)
Inventor: DAVE KAUSHIK J
IPC: A61K51/00
Filed: 2016-05-20
Abstract: A patient specific therapeutic composition provided in a single dose container, the total volume of which may be administered to a patient in a single treatment session. The composition includes a monoclonal antibody having a labeled fraction and an unlabeled fraction, and a pharmaceutically acceptable carrier. The label may be any of a radioisotope or a drug such as a chemotherapeutic or cytotoxic agent. The amount of the monoclonal antibody and any conjugated label molecule may depend on at least one patient specific parameter selected from a patient weight, a patient age, a patient height, a patient gender, a patient medical condition, and a patient medical history. Methods of administration, production, and articles of manufacture comprising the patient specific therapeutic composition are also disclosed.
Patent CA-2987912-A1 (CA)
Inventor: KOTHARI SANJEEV
IPC: A61K9/28
Filed: 2016-06-29
Abstract: The present disclosure relates generally to rapid-release pharmaceutical dosage unit tablets containing a drug that is an inhibitor of the mitogen-activated protein kinase enzyme, a filler and a disintegrant, and to processes for forming the tablets. More specifically, the present disclosure relates to pharmaceutical dosage unit tablets containing cobimetinib, a least one filler, at least one lubricant and at least one disintegrant, and to methods for preparing the tablets from granules formed by dry granulation.
Patent CA-2989233-A1 (CA)
Title: Echelle a poisson a chicane laterale en alternance destinee a faire passer le poisson dans les barrages ou les barrieres naturelles
Inventor: KYNARD BOYD
IPC: E02B8/08
Filed: 2017-12-18
Abstract: Une échelle à poissons comprend un canal avec une première et une deuxième paroi latérale espacées dune distance égale à la largeur dun canal. De premières chicanes latérales sont attachées à la première paroi latérale et de deuxièmes chicanes latérales sont attachées à la deuxième paroi latérale. Chaque chicane latérale sétend sur une distance prédéterminée dans le canal. Une première distance de largeur douverture de fente dun bout de chacune des premières chicanes latérales sur le canal et perpendiculaire à la deuxième paroi latérale est essentiellement égale à une deuxième distance de largeur douverture de fente dun bout de chacune des deuxièmes chicanes latérales sur le canal et perpendiculaire à la première paroi latérale. Une distance despacement de chicane latérale dun bout des premières chicanes latérales et perpendiculaire à une distance correspondante des deuxièmes chicanes latérales en amont est essentiellement égale aux première et deuxième distances de largeur douverture de fente.
Patent CA-2989475-A1 (CA)
Title: Methode de pompage d'un fluide de trou de forage
Inventor: SIMPSON ALASTAIR
IPC: F04D3/02
Filed: 2011-07-27
Abstract: Un mécanisme de pompe comprenant un stator et un rotor ayant des aubes darrangements filetés de main opposée est décrit. Un espace radial est situé entre les aubes du stator et les aubes du rotor de sorte que la rotation du rotor entraîne le stator et le rotor à coopérer pour fournir un système de déplacement de fluide de manière longitudinale entre eux. Lopération de la pompe produit la formation dun joint de fluide sur lespace radial. Lappareil décrit peut également être utilisé comme mécanisme de moteur lorsquun fluide est dirigé pour être déplacé de manière longitudinale entre le stator et le rotor. La présence du joint de fluide ne produit pas de détérioration de lefficacité de la pompe ou du moteur, même quand lespace radial est significativement plus grand que les valeurs normales de dégagement fonctionnel. De plus, la présence de lespace radial rend le mécanisme de pompe/moteur idéal pour le déploiement de fluides à viscosité élevée ou multiphasés.
Patent CA-2989497-A1 (CA)
Title: Methods for diagnosis of bladder cancer
Inventor: LIAO JOSEPH C
IPC: C12Q1/6886
Filed: 2017-12-18
Abstract: Methods for diagnosis of bladder cancer are disclosed. In particular, the invention relates to the use of urinary biomarkers for aiding diagnosis, prognosis, and treatment of bladder cancer, and to a panel of biomarkers that can be used to distinguish high-grade bladder cancer from low-grade bladder cancer.
Patent CA-2990448-A1 (CA)
Inventor: LUBIC MARKO K
IPC: A01K39/01
Filed: 2017-12-28
Abstract: Il est décrit un verrou de couvercle de câble de mangeoire doiseaux pour une mangeoire doiseaux ayant un corps de réservoir avec un couvercle amovible doté dune ouverture, et un câble enfilé dans louverture et auquel la mangeoire est accrochée pendant lutilisation. Le verrou de couvercle de câble comprend une vis colonne ayant un trou axial dans lequel le câble suspendu est enfilé et un élément de base fileté à lintérieur en saillie du couvercle et ayant un alésage à épaulement ou conique avec un diamètre allant en rétrécissant qui reçoit la vis. La vis a une coupe profilée dans la tige pour former au moins deux bras sur des côtés différents du câble. Les bras sont pressés lun contre lautre à mesure que la vis est serrée dans lalésage, serrant le câble où il sétend dans la vis et exerçant une force normale qui, par friction, crée une action de verrouillage sur le câble pour fixer le couvercle contre le corps de réservoir de la mangeoire.
Patent CA-2990492-A1 (CA)
Inventor: BARUAH HEMANTA
IPC: C12N15/09
Filed: 2016-08-09
Abstract: Provided herein are antibodies that bind human programmed cell death 1 (PD-1) ,and their use for treating cancer alone or in combination with chemotherapy and other cancer therapeutics.
Patent CA-2991637-A1 (CA)
Title: Methodes de traitement de troubles medies par l'hepcidine
Inventor: KAKKAR RAHUL
IPC: C12Q1/68
Filed: 2016-07-28
Abstract: L'invention concerne des méthodes pour le traitement de troubles médiés par l'hepcidine sur la base de génotypes TMPRSS6.
Patent CA-2992410-A1 (CA)
Title: Hydroxytriazine compounds and pharmaceutical use thereof
Inventor: MITANI IKUO
IPC: A61P27/06
Filed: 2016-08-16
Abstract: The present invention provides a compound that has inhibiting activity against mPGES-1 and is useful in the prevention or treatment of pain, rheumatoid arthritis, osteoarthritis, fever, Alzheimer's disease, multiple sclerosis, arteriosclerosis, glaucoma, ocular hypertension, ischemic retinoapthy, systemic scleroderma and/or malignant tumor such as colon cancer. The present invention relates to the compound of formula [I-a], [I-b], or [I-c] or a pharmaceutically acceptable salt thereof. (Each symbol in the formulas is as defined in the description.)
Patent CA-2993039-A1 (CA)
Inventor: HIYOSHI RYOUSUKE
IPC: F02B75/04
Filed: 2015-07-21
Abstract: A stopper (32) has: a side wall (33) on one end side, which faces one end surface of a control shaft-side connection pin (30) irrespective of the rotational position of a control shaft (10); a side wall (34) on the other end side, which faces the other end surface of the control shaft-side connection pin (30) irrespective of the rotational position of the control shaft (10); a flange (36) on one end side, which is affixed to an oil pan upper portion; and a flange (37) on the other end side, which is affixed to the oil pan upper portion. As a result of this configuration, when viewed in the axial direction of the control shaft-side connection pin, the end surfaces of the control shaft-side connection pin (30) partially overlap, irrespective of the rotational position of the control shaft (10), the side wall (33) on one end side and the side wall (34) on the other end side, which belong to the stopper (32). Consequently, irrespective of the rotational position of the control shaft (10), the control shaft-side connection pin (30) can be reliably prevented from becoming dislodged in the axial direction of the control shaft-side connection pin.
Patent CA-2995838-A1 (CA)
Inventor: ANDERSON STEPHEN
IPC: C07K16/38
Filed: 2016-08-18
Abstract: The invention describes a method of generating antibodies to a mixture of peptidogenic proteins wherein the peptidogenic protein has altered conformational dynamics as compared to a starting protein and wherein the peptidogenic protein has a similar conformation to the starting protein. The peptidogenic proteins can be used to induce an immune response, which can lead to the generation of antibodies and/or can be used to vaccinate a mammal.
Patent CA-2998379-A1 (CA)
Title: Pre-heating and thermal control of work rolls in metal rolling processes and control systems thereof
Inventor: GAENSBAUER DAVID ANTHONY
IPC: B21B37/32
Filed: 2016-09-21
Abstract: Systems and methods for using full-width hot sprays 118 to pre-heat rolling mills 100 prior to processing of metal sheet or plate are described herein. The hot sprays 118 may be individually controlled. Using hot sprays can allow the rolling mill 100 to reach operating temperature and achieve a desired thermal crown so that metal sheet or plate 102 may be processed immediately within tolerances for flatness and gauge accuracy. Pre-heating of rolling mills 100 can eliminate the need of the rolling mill 100 to operate in a transitional period of work roll heating and can increase efficiency by eliminating or reducing scrap material and mill downtime. Hot sprays 118 may also be incorporated with existing coolant systems to provide thermal control systems for rolling mills 100 with bi-directional temperature controls.
Patent CA-2998790-A1 (CA)
Title: Everting end effector for use with an articulated arm in a robotic system
Inventor: WAGNER THOMAS
IPC: B25J15/00
Filed: 2016-09-15
Abstract: An end effector is disclosed for an articulated arm in a robotic system. The end effector includes an enclosed flexible membrane generally in the form of an annulus that contains a fluid within the membrane.
Patent CA-3002992-A1 (CA)
Inventor: HETTAK KHELIFA
IPC: H05K1/16
Filed: 2018-04-26
Abstract: An electronic component such as a voltage controllable reconfigurable capacitor or transistor is formed by printing one or more layers of ink on a non-conductive substrate. Ferroelectric ink or semi-conductive ink is printed and conductive resistive or dielectric ink is printed on a s same or different layers. Reconfigurability is achieved by printing resistive biasing circuitry wherein when a changing voltage is applied to the biasing circuitry, an electronic property of the electronic component changes in response to the changing voltage.
Patent CA-3004488-A1 (CA)
Title: Information processing network based on uniform code issuance, method therefor, and sensing access device
Inventor: XU WEI
IPC: G06Q50/00
Filed: 2015-10-09
Abstract: The present invention relates to an information processing network and method based on uniform code sending and a sensing access device. The method comprises: a publisher sending a corresponding code sending request to a core administrator, and the core administrator or a code sending mechanism authorized thereby generating an encoding medium; and enabling an access requester to obtain information matching the identified encoding medium when identifying the encoding medium by means of an equipped sensing access device, thereby obtaining the following information provided by the publisher, containing: information to be published by the publisher, an attribute status of the publisher, an attribute status of an interaction party associated with the publisher and information obtained by identifying other encoding media by the equipped sensing access device of the publisher. By means of the present invention, scenario-based specific theme accessing can be performed by means of various sensing access methods, various nodes of an information spreading process are precisely traced back, and value quantification and implementation based on the field of circulation are realized.
Patent CA-3006055-A1 (CA)
Inventor: LEI YUGUO
IPC: C12M3/02
Filed: 2016-11-23
Abstract: Methods of culturing and manufacturing of cells on a large-scale level are disclosed. Particularly, a manufacturing system and device, and methods of using the system and device for culturing and manufacturing cells in hollow fibers made from alginate polymers are provided.
Patent CA-3006113-A1 (CA)
Inventor: THOMAS WILLIAM C
IPC: B08B9/043
Filed: 2018-05-23
Abstract: A Knuckle Jointed Lance (KJL), comprising a segmented lance including a plurality of connected KJL segments in a concatenated string thereof. The first end of one KJL segment is rotatably connected to the second end of a neighboring KJL segment via a pinned connection. Responsive to user assignment of a predetermined length to each KJL segment in the concatenated string according to the KJL segment's corresponding pre-ordained position in the concatenated string, the lance is disposed to spool onto a reel in "nested" fashion, such that as the lance makes spooling revolutions onto the reel, (a) KJL segments stack in circumferential registered layers around the reel and (b) pinned connections trace substantially radial vectors from a center of the reel. Other embodiments provide additional features to facilitate nesting and to generally strengthen the KJL.
Patent CA-3008069-A1 (CA)
Title: Method for producing a high strength coated steel sheet having improved ductility and formability, and obtained coated steel sheet
Inventor: GOSPODINOVA MAYA
IPC: C22C38/12
Filed: 2016-12-21
Abstract: A method for producing a coated steel sheet having a tensile strength TS of at least 100 MPa, a total elongation TE according to ISO standard 6892-1 of at least 12%, the product TSxTE of the tensile strength by the total elongation being at least 14200 MPa%, and a hole expansion ratio HER according to ISO standard 16630:2009 of at least 25%, comprising the following successive steps: - providing a cold-rolled steel sheet, the chemical composition of the steel containing in weight %:0.15% = C = 0.23%, 2.0 % = Mn = 2.7%, with C+Mn/10 = 0.420%, 0 = Cr = 0.40%, with Mn + Cr = 2.25%, 0.2% = Si = 1.6%, 0.02% = Al = 1.2%, with 1.0 % = Si+Al = 2.2%, 0 = Nb = 0.035 %, 0 = Mo = 0.1%, the remainder being Fe and unavoidable impurities, - annealing the steel sheet at an annealing temperature TA so as to obtain a structure comprising at least 65% of austenite and at most 35% of intercritical ferrite, - quenching the sheet from a temperature of at least 600°C at a cooling rate comprised between 20°C/s and 50°C/s down to a quenching temperature QT between 200°C and 270°C, - heating the sheet up to a partitioning temperature PT comprised between 400°C and 480°C and maintaining the sheet at this partitioning temperature PT for a partitioning time Pt comprised between 50s and 250s, - hot-dip coating the sheet at a temperature less than 515°C, - cooling the coated sheet down to the room temperature, the steel sheet having a microstructure consisting of, in surface fraction : between 3 % and 15% of retained austenite, at least 30% of tempered martensite, at most 5% of fresh martensite, at most 35% of bainite, the sum of the surface fractions of tempered martensite, fresh martensite and bainite being comprised between 55% and 92%, and between 5% and 35% of ferrite.