baber/WOPTO huggingface dataset:
Patent CN-114345297-A (CN)
Inventor: ZENG YONGPING
IPC: B01D53/02
Filed: 2022-01-10
Abstract: 本发明公开了一种磁性活性炭的制备方法及其在烟气脱汞中的应用，涉及复合材料制备技术领域，包括如下步骤：（1）按比例称取活性炭、铁的可溶性盐、镍的可溶性盐和锌的可溶性盐溶于无水乙醇或去离子水中，搅拌均匀得到混合溶液，（2）将步骤（1）得到的混合溶液在氮气氛围下300‑500℃焙烧1‑4 h后停止加热，在氮气氛围中冷却至室温后，得到磁性活性炭。本发明的磁性活性炭材料中的磁性介质为Ni 0.5 Zn 0.5 Fe 2 O 4 纳米材料，其磁性更强，分散性好，吸附性能更持久稳定，Ni、Zn、Fe元素的存在既增强了磁性活性炭脱汞性能又更易于磁性分离回收再利用。
Patent CN-114281389-A (CN)
Inventor: LI SHENGKAI
IPC: G06F8/61
Filed: 2022-01-26
Abstract: 本公开提供了用于片上系统SOC升级的方法，应用于目标中央处理器CPU核心，该SOC包含至少两个CPU核心，该目标CPU核心是该至少两个中央处理器CPU核心中的一个，涉及计算机技术领域，尤其涉及片上系统和智能驾驶技术领域。具体实现方案为：读取预设的配置文件；基于该预设的配置文件，确定该目标CPU核心的角色，其中，该角色包括主核或从核；根据所确定的角色，执行以下两者中的一者：响应于确定该角色为主核，根据检测到的来自该SOC外部的升级指令进行主核刷写；响应于确定该角色为从核，停止与该SOC外部的通信。
Patent MY-179977-A (MY)
Title: An intelligent fuzzy logic dynamic bandwidth allocation algorithm for upstream ethernet passive optical network
Inventor: ASSOC PROF DR NORASHIDAH BINTI MD DIN
Filed: 2010-01-21
Abstract: Ethernet passive optical network (EPON) is a promising broadband access technology for application in high-capacity wired access networks. The proposed invention is generally a fuzzy-logic-based dynamic bandwidth allocation (OBA) algorithm for use in an upstream EPON which covers the allotment for inter-ONU and intra-ONU. The dynamic bandwidth allocation system comprises of an optical line terminal (OLT, 1), a multiplicity of optical network units (ONU,2); and a splitter (3) adapted to connect the optical line terminal (1) to the multiplicity of optical network units (2). The optical line terminal (1) is arranged with a means for assigning bandwidth to the multiple optical network units using an inter-ONU algorithm and/or intra-ONU algorithm in the form of a fuzzy logic regulator (4). The dynamic bandwidth allocation is executed in according to different classes of traffic assignment priority. Simulations are used to show performance and accuracy of the algorithm. Compared with a OBA algorithm that is not using fuzzy logic, the results show significant performance improvements in terms of the bandwidth utilization and the fairness.
Patent MY-155848-A (MY)
Title: Free-of-bearing rotational positioning device for a dewatering basket of a non-treading type wringer bucket
Inventor: YUNG-HUA CHEN
IPC: A47L13/58
Filed: 2010-05-25
Abstract: A FREE-OF-BEARING ROTATIONAL POSITIONING DEVICE FOR A DEWATERING BASKET OF A NON-TREADING TYPE WRINGER BUCKET COMPRISING: A BUCKET BODY (10) HAVING A DEWATERING BASKET (20) HAVING A DRIVEN SEAT (21) AT THE CENTER OF THE BOTTOM THEREOF. THE BOTTOM OF THE DRIVEN SEAT (21) INCLUDES A SHAFT HOLDER (30) MADE OF NON-METAL MATERIAL. IN MOUNTING THE DEWATERING BASKET (20), THE DRIVEN SEAT (21) FITS FROM TOP TO BOTTOM OVER THE CONNECTION PART OF THE SUPPORT SHAFT (50). AFTER THE LOWER SLEEVE (30A) PASSES THROUGH POSITIONING ELEMENT (40) IN A COMPRESSION MANNER, THE POSITIONING SURFACE (421) OF THE POSITIONING ELEMENT (40) IS STRETCHED INTO THE ENGAGEMENT GROOVE (36) AT THE CENTER OF THE SHAFT HOLDER (30) WHEN RETURNING TO ITS ORIGINAL SHAPE. FIG 5.
Patent MY-157196-A (MY)
Title: Methods and systems for active sound attenuation in an air handling unit
Inventor: HOPKINS LAWRENCE G
IPC: F04D29/66
Filed: 2011-03-14
Abstract: A SYSTEM AND METHOD FOR CONTROLLING NOISE PRODUCED BY AN AIR HANDLING SYSTEM IS PROVIDED. THE SYSTEM INCLUDES A SOURCE MICROPHONE (270, 510, 552, 610, 668) TO COLLECT SOUND MEASUREMENTS FROM THE AIR HANDLING SYSTEM AND A PROCESSOR TO DEFINE A CANCELLATION SIGNAL THAT AT LEAST PARTIALLY CANCELS OUT THE SOUND MEASUREMENTS. THE SYSTEM ALSO INCLUDES A SPEAKER (274) TO GENERATE THE CANCELLATION SIGNAL. THE SOUND MEASUREMENTS ARE AT LEAST PARTIALLY CANCELED OUT WITHIN A REGION OF CANCELLATION. ACCORDINGLY, THE SYSTEM FURTHER INCLUDES A RESPONSE MICROPHONE (274, 514) TO COLLECT RESPONSE SOUND MEASUREMENTS AT THE REGION OF CANCELLATION. THE PROCESSOR TUNES THE CANCELLATION SIGNAL BASED ON THE RESPONSE SOUND MEASUREMENTS. THE MOST ILLUSTRATIVE DRAWING IS
Patent MY-166695-A (MY)
Title: Cartridge holder, drug delivery device and method for securing a cartridge in a cartridge holder
Inventor: RAAB STEFFEN
IPC: A61M5/24
Filed: 2011-01-31
Abstract: A CARTRIDGE HOLDER (2), WHICH HAS A DISTAL END AND A PROXIMAL END, COMPRISES A COUPLING HOUSING PORTION (14) IN WHICH A CARTRIDGE CAN BE INSERTED AT LEAST PARTLY. THE COUPLING HOUSING PORTION (14) IS CONFIGURED TO BE COUPLED TO A PART OF A DRUG DELIVERY DEVICE. THE CARTRIDGE HOLDER (2) FURTHER COMPRISES A FIXING MEMBER (21) WHICH IS CONNECTED WITH THE COUPLING HOUSING PORTION (14). THE FIXING MEMBER (21) IS MOVEABLE RADIALLY INWARDLY TO A POSITION IN WHICH THE FIXING MEMBER (21) IS SUITABLE FOR SECURING THE CARTRIDGE AGAINST DISTAL DISPLACEMENT OF THE CARTRIDGE. (FIGURE 2)
Patent MY-184254-A (MY)
Title: A system for monitoring performance indicators of a compressor
Inventor: SHAHARIN A SULAIMAN
Filed: 2012-12-14
Abstract: A system to calculate the performance indicators of a compressor is provided. The system includes a computer processor (121) and a memory unit containing a program to be executed the processor to enable the system to interact with a user. The system requires a user to enter compressor data, gas composition data and compressor model to calculate a current performance indicator set viz . isentropic efficiency, isentropic head, and gas power. The compressor data comprises suction pressure, discharge pressure , suction temperature, discharge temperature, rotational speed, inlet standard flow rate, compressor running hours and remarks. The method also discloses calculation of deviation of the previous indicators from the current previous indicators. The method further discloses estimation of the date of maintenance of the compressors. A display unit (315) can display the calculated or estimated compressor performance indicators and related additional data.
Patent MY-170097-A (MY)
Title: Agents for exterminating parasites on fish and method of exterminating the same
Inventor: HIRAZAWA NORITAKA
Filed: 2011-06-28
Abstract: A method of exterminating a parasite on fish characterized by administering a salicylanilide drug to fish is disclosed. This method is effective against monogenetic parasites or trematodes. Oxyclozanide, rafoxanide, or closantel is preferred as the salicylanilide drug. The method is effective for fish of the order Perciformes, the order Pleuronectiformes, the order Clupeiformes, the order Tetradontiformes, the order Cypriniformes, the order Anguiliformes, or the order Siluriformes.
Patent MY-168843-A (MY)
Title: A hybrid fiber-radio transmission system and method thereof
Inventor: SYAMSURI BIN YAAKOB
Filed: 2013-01-04
Abstract: The present invention relates to a hybrid fiber-radio transmission system comprises a central office (100) that is interconnected with more than one remote antenna unit (140) for distributing multiple radio signals over fiber in millimeter-wave fiber - radio applications, the central office (100) adapted to generate multiple RF carriers at different wavelength by spectrally splicing a broadband light source, and thereafter modulate each of multiple RF carriers with different base-band data. The modulated RF carriers are then merged together and transmitted through a single mode transmission fiber (110) to the more than one remote antenna unit (140) for optical-to-electrical signals conversion.    Most illustrative diagram: Figure 1
Patent MY-165181-A (MY)
Title: Optical coherence tomographic apparatus
Inventor: HIROFUMI YOSHIDA
IPC: G01N21/17
Filed: 2013-01-25
Abstract: AN OPTICAL COHERENCE TOMOGRAPHIC APPARATUS WHICH OBTAINS A TOMOGRAPHIC IMAGE BY COMBINING RETURN LIGHT FROM AN OBJECT IRRADIATED WITH MEASUREMENT LIGHT THROUGH A FIRST LENS (101-1) AND CORRESPONDING REFERENCE LIGHT, COMPRISING: A SCANNING UNIT (122-1, 122-2) CONFIGURED TO BE PROVIDED ON AN OPTICAL PATH OF THE MEASUREMENT LIGHT AND TO SCAN THE MEASUREMENT LIGHT ON THE OBJECT; A SECOND LENS (101-3) CONFIGURED TO BE DISPOSED BETWEEN THE SCANNING UNIT AND THE FIRST LENS (101-1) ON THE OPTICAL PATH OF THE MEASUREMENT LIGHT BRANCH OFF TO AN OBSERVATION OPTICAL PATH FOR OBSERVATION OF THE OBJECT; WHEREIN THE SECOND LENS AND THE SCANNING UNIT ARE DISPOSED SO AS TO HOLD AN INCIDENT ANGLE OF THE MEASUREMENT LIGHT SCANNED BY THE SCANNING UNIT ON THE BRANCHING UNIT.
Patent MY-168850-A (MY)
Title: Wrapped package with opening tab
Inventor: REVELLY JACQUES
Filed: 2011-12-22
Abstract: A wrapped package (10) of consumer goods comprises: a filled package (12) containing one or more consumer goods; and an outer wrapper (14), wrapped around the filled package such that first (16a) and second (16b) opposed edges of the outer wrapper overlap with each other along a longitudinal overlapping region (18) extending across a first side of the package. The outer wrapper (14) is provided with a opening cut (22) extending transversely at least part way across the longitudinal overlapping region (18) to define an opening tab (24) in the outer wrapper (14).    FIGURE 1
Patent MY-161744-A (MY)
Title: Polishing composition containing hybrid abrasive for nickel-phosphorous coated memory disks
Inventor: RUJEE LORPITTHAYA
IPC: C09K3/14
Filed: 2013-08-26
Abstract: THE INVENTION PROVIDES A POLISHING COMPOSITION THAT CONTAINS (A) AN ABRASIVE COMPRISING (I) FIRST ALPHA ALUMINA PARTICLES THAT HAVE AN AVERAGE ASPECT RATIO OF 0.8:1 TO 1.2:1, (II) SECOND ALPHA ALUMINA THAT HAVE AN AVERAGE ASPECT RATIO OF GREATER THAN 1.2:1, (III) FUMED ALUMINA PARTICLES, AND (IV) WET-PROCESS SILICA PARTICLES, AND (B) WATER. THE INVENTION ALSO PROVIDES A METHOD OF POLISHING A SUBSTRATE, ESPECIALLY A NICKEL-PHOSPHOROUS SUBSTRATE, WITH THE POLISHING COMPOSITION. (FIG 1)
Patent MY-161387-A (MY)
Title: Pharmaceutical compositions for preventing and/or treating an hiv disease in humans
Inventor: ANDRIEU JEAN-MARIE
IPC: A61P31/18
Filed: 2012-04-06
Abstract: THE PRESENT INVENTION RELATES TO PHARMACEUTICAL COMPOSITIONS COMPRISING A MIXTURE OF A SPECIFIC HIV ANTIGEN AND A NON-PATHOGENIC LIVING BACTERIUM. SAID SPECIFIC HIV ANTIGEN COMPRISES ONE OR MORE EPITOPES FROM GAG AND/OR POL PROTEINS AND IS PREFERABLY UNDER A PARTICULATE FORM. SAID BACTERIUM IS PREFERABLY LACTOBACILLUS PLANTARUM. THESE COMPOSITIONS ARE USEFUL FOR PREVENTING AND/OR TREATING AN HIV DISEASE IN HUMANS. (NO SUITABLE
Patent MY-171655-A (MY)
Title: Signaling of layer identifiers for operation points
Inventor: WANG YE-KUI
IPC: H04N19/46
Filed: 2013-10-01
Abstract: A device for processing video data receives (162) an indication of a maximum layer identification (ID) value for a bitstream; receives (164) a flag for a first layer with a layer ID value less than the maximum layer ID value; and, based on a value of the flag, determines (166) if the first layer is included in an operation point.
Patent MY-176190-A (MY)
Title: System and method for maintaining water quality in large water bodies
Inventor: FERNANDO BENJAMIN FISCHMANN TORRES
Filed: 2014-12-29
Abstract: The present application relates to an innovative and optimized method and system for maintaining water quality in water bodies such as excavated inland structures and floating structures with bottoms (2) comprising flexible membranes, using a simplified economic filtration system and degreasing system (50) that requires much smaller filtration equipment than conventional centralized filtration systems and provides for consumption of significantly lower amounts of energy. The method of the invention allows activating a chemical application system, mobile suctioning device, and/or degreasing system (50) based on information regarding turbidity, the color of the bottom (2) of the water body (1; 142), and amount of greases on the surface water layer of the water body (1; 142), to adjust the water quality parameters within their limits.
Patent MY-179842-A (MY)
Title: Soda-lime glass from 100% recycled glass-forming materials
Inventor: BROUWER ROBERT
Filed: 2014-10-20
Abstract: A method of making soda-lime glass using 100 wt.% cullet as the glass forming materials is disclosed. Also disclosed is a soda-lime glass container made according to this method.
Patent MY-178485-A (MY)
Title: A microelectronic packaging
Inventor: AZMAN BIN JALIL @ JALAR
Filed: 2016-09-14
Abstract: The present invention relates to a microelectronic packaging of microelectronic substrates together. The present invention comprising: a non-soldered mechanical interlocking adhesive piece, characterized in that: a male joint (100) including an interlocking-shaped protrusion (101); a female joint (200) including an interlocking-shaped engrave (201) which interlocks with the protrusion (101) of the male joint (100); a non-conductive resin (300) encapsulating the male (100) and female (200) joints to provide strong adhesion; an adhesive surface (400) arranged beside the non-conductive resin (300) of the male (100) and female (200) joints, the adhesive surface (400) is covered by a cover-layer (401); a conductive masking (500) of the adhesive surface (400) located between each the male (100) and the female (200) joint and the adhesive surface (400); and a void area (600) between the two conductive resins of the male (100) and the female (200) joints upon fixation for heat dissipation.  Figure 1
Patent MY-171892-A (MY)
Title: Upper wear
Inventor: MITSUI YUSUKE
Filed: 2017-12-05
Abstract: Provided is an upper wear allowing an increase in variations of wear coordination of the upper wear.	An upper wear (1) includes a front panel (10) having front panel pieces (50) and (51) at left and right. The upper wear (1) is configured such that respective upper parts of the left and right front panel pieces (50) and (51) can be folded back to the back surface sides thereof, to be held at the back surfaces of the front panel pieces (50) and (51), respectively.
Patent MY-187933-A (MY)
Title: Compositions and methods for internalizing enzymes
Inventor: BAIK ANDREW
IPC: C12N9/40
Filed: 2016-12-08
Abstract: Compositions and methods for treating lysosomal storage diseases are disclosed. Biotherapeutic complexes containing an internalization effector binding domain and a lysosomal replacement enzyme activity are disclosed. The biotherapeutic complexes are capable of entering cells, segregating to the lysosome, and delivering the replacement enzyme activity to the lysosome.
Patent MY-192681-A (MY)
Title: Improved energy saving lamps
Inventor: Paul David Millott
IPC: H01J65/04
Filed: 2018-07-17
Abstract: An improved energy saving lamp (40) with much less gas filled in the glass envelope due to the formation of a void (44) created by first outer glass tube (41) and second inner glass tube (42). Only a small amount of gas is required to be filled at the void and much lesser power to energise the atoms and electrons. In contrast to the current trimmer energy saving lamps, the present invention maintains the lamp brightness since the reduction cross surface area which contains gas volume following the changes lamp geometry remains the same light emitting surface area of the convention lamps. (Figure 4)
Patent MY-196527-A (MY)
Title: High Throughput Cell-Based Screening for Aptamers
Inventor: GUO XUECUI
IPC: C12Q1/68
Filed: 2017-08-03
Abstract: The invention provides eukaryotic cell-based screening methods to identify an aptamer that specifically binds a ligand, or a ligand that specifically binds an aptamer, using a polynucleotide cassette for the regulation of the expression of a reporter gene where the polynucleotide cassette contains a riboswitch in the context of a 5 intron-altemative exon-3 intron. The riboswitch comprises an effector region and an aptamer such that when the aptamer binds a ligand, reporter gene expression occurs.
Patent MY-196336-A (MY)
Title: Washing Machine
Inventor: NASU KAZUAKI
IPC: D06F39/02
Filed: 2018-07-18
Abstract: A washing machine (100) includes: a housing (101); a water tub (105) supported inside the housing (101); a washing tub (106) rotatably provided inside the water tub (105); tank (117, 126) including upper face opening (118) for feeding a liquid agent provided at an upper part of the tank (117, 126), and discharge port (123) configured to discharge the liquid agent provided at a lower part of the tank (117, 126); and an automatic liquid-agent feeding device (109) configured to supply the liquid agent stored in tank (117, 126) into the washing tub (106). Tank (117, 126) includes mesh member (122) having a net shape between upper face opening (118) and discharge port (123). With this configuration, the washing machine (100) that facilitates detaching of mesh member (122) from tank (117, 126) can be provided. (Figure 10)
Patent MY-168553-A (MY)
Title: Bucket for rotatable mop
Inventor: CHING-CHUN LIN
Filed: 2012-01-13
Abstract: A bucket for rotatable mop has a bucket assembly (10), a base assembly (20) and a gear assembly (30). The gear assembly (30) engages a pedal (25) and a pintle (24), and has multiple gears with different numbers of teeth, so the gear assembly (30) can offer an accelerating effect from the pedal (25) to the pintle (24). The pintle (24) drives a dryer basket (13) with a rotatable mop to rotate. Therefore the rotatable mop can rotate faster and for more circles each time the user treads on the pedal (25).   Fig. 1
Patent SG-10201703160S-A (SG)
Title: Perfume transfer device
Inventor: Jason Oon Kok Kiang
Filed: 2017-04-18
Abstract: PERFUME TRANSFER DEVICE The invention discloses a device that facilitates the transfer of liquid by leveraging on the spraying mechanism present in perfume bottles. The device is complementary to existing perfume bottles and allows for the repeated transfer of perfume, while minimizing spillages. Figure 1
Patent SG-10201802524V-A (SG)
Title: Brake health indicator systems using input and output energy
Inventor: ALAM SHAHRIAR
Filed: 2018-03-27
Abstract: BRAKE HEALTH INDICATOR SYSTEMS USING INPUT AND OUTPUT ENERGY Systems and methods for indicating the health of brakes on an aircraft or a ground vehicle. One method for monitoring brake health calculates the ratio of input 5 energy to output energy during braking. The input energy is a function of commanded brake force and speed. The output energy may be measured by measuring the increase in temperature or the actual brake force over time during brake application. When using brake temperatures, the temperatures in a pair of brakes may optionally be compared. If the respective measured temperatures of the two brakes differ by an 10 amount that exceeds a specified threshold, the system produces an indication that one brake may require repair or replacement. Variability due to operational and environmental factors that affect measured temperature can be reduced by comparing the measured brake temperatures for one brake with selected brake temperature data collected from the same brake during other landings under similar conditions. 15 Fig. 2
Patent SG-10201804422V-A (SG)
Title: Photomask Blank and Making Method
Inventor: KOSAKA TAKURO
Filed: 2018-05-24
Abstract: Photomask Blank and Making Method 5 A photomask blank is processed into a transmissive photomask for use in photolithography for forming a pattern on a recipient using exposure light. The photomask blank comprises a transparent substrate, a first film of a material which is etchable by chlorine/oxygen-based dry etching, and a second film of a silicon-containing material. The second film includes a layer having a refractive index n of at least 1.6 or an extinction 10 coefficient k of at least 0.3 with respect to the wavelength of inspection light which is longer than the exposure light. Fig. 1
Patent SG-10201808449U-A (SG)
Title: Circuits And Methods Related To Radio-Frequency Receivers Having Carrier Aggregation
Inventor: WLOCZYSIAK STEPHANE RICHARD MARIE
Filed: 2015-04-10
Abstract: CIRCUITS AND METHODS RELATED TO RADIO-FREQUENCY RECEIVERS HAVING CARRIER AGGREGATION Circuits and methods related to radio-frequency (RF) receivers having carrier aggregation. In some embodiments, a carrier aggregation (CA) circuit can include a first filter configured to allow operation in a first frequency band, and a second filter configured to allow operation in a second frequency band. The CA circuit can further include a first path implemented between the first filter and a common node, with the first path being configured to provide a substantially matched impedance for the first frequency band and a substantially open-circuit impedance for the second frequency band. The CA circuit can further include a second path implemented between the second filter and the common node, with the second path being configured to provide a substantially matched impedance for the second frequency band and a substantially open-circuit impedance for the first frequency band. Figure 1
Patent SG-11201810602Y-A (SG)
Title: Method of treating liver fibrosis
Inventor: MIAO ZHENHUA
IPC: A61K31/18
Filed: 2017-06-02
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 07 December 2017 (07.12.2017) WIP0 I Iiiimmoimiolollmolommioloiollmoiomionom oimIE (10) International Publication Number WO 2017/210526 Al PCT (51) International Patent Classification: A61K 31/4375 (2006.01) A61K 31/18 (2006.01) (21) International Application Number: PCT/US2017/035628 (22) International Filing Date: 02 June 2017 (02.06.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/345,086 03 June 2016 (03.06.2016) US (71) Applicant: CHEMOCENTRYX, INC. [US/US]; 850 Maude Avenue, Mountain View, CA 94043 (US). (72) Inventors: MIAO, Zhenhua; 6891 Dartmoor Way, San Jsoe, CA 95129 (US). CHARO, Israel; 850 Maude Av- enue, Mountain View, CA 94043 (US). (74) Agent: MARSHALL, Ryan, L.; Brinks Gilson & Lione, P.O. Box 10087, Chicago, IL 60610 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) = (54) Title: METHOD OF TREATING LIVER FIBROSIS Figure 1: Change in body weight in HFD/fructose-induced NASH model Body Weight 80- Treatment Started 60- Z C D 40- rl 0 CO 20- 0 0 10 20 30 40 50 Cl> 14\") Weeks 1-1 © (57) : A method of treating liver fibrosis with CCR2 antagonists is provided. The liver fibrosis may be associated with non- e , ' alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), emerging cirrhosis, non-cirrhotic hepatic fibrosis, type C..? 2 diabetes mellitus (T2DM) or metabolic syndrome (MS). — Compound 1 SC Vehicle — Control Diet
Patent SG-11201810935S-A (SG)
Title: Injectable solution at ph 7 comprising at least one basal insulin having a pi of between 5.8 and 8.5 and a copolyamino acid bearing carboxylate charges and hydrophobic radicals
Inventor: GEISSLER ALEXANDRE
IPC: A61K47/34
Filed: 2017-06-07
Abstract: INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN HAVING A PI OF BETWEEN 5.8 AND 8.5 AND A COPOLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS [0001] The invention relates to physically stable compositions in the form of an injectable aqueous solution, the pH of which is from 6.0 to 8.0, comprising at least: a) a basal insulin of which the isoelectric point (pI) is from 5.8 to 8.5, and b) a co-polyamino acid bearing carboxylate charges and at least one hydrophobic radical.