Patent EP-0584764-A1 (EP)
Inventor: YOKOYAMA YASUHIRO C O MENICON
IPC: C08F290/00
Filed: 1993-08-23
Abstract: An ocular lens material made of a copolymer consisting essentially of (A) a polysiloxane macromonomer having polymerizable groups bonded via one or more urethane bonds to the siloxane main chain, of the formula (I): 
 
 
 
        A¹-U¹-(-S¹-U²-) n -S²-U³-A²   (I) 
 
 
 
wherein A¹ is a group of the formula (II): 
 
 
 
        Y²¹-R³¹-   (II) 
 
 
 
wherein Y²¹ is an acryloyloxy group, a methacryloyloxy group, a vinyl group or an allyl group, and R³¹ is a linear or branched alkylene group having from 2 to 6 carbon atoms; 
   A² is a group of the formula (III): 
 
 
 
        -R³⁴-Y²²   (III) 
 
 
 
wherein Y²² is an acryloyloxy group, a methacryloyloxy group, a vinyl group or an allyl group, and R³⁴ is a linear or branched alkylene group having from 2 to 6 carbon atoms; 
   U¹ is a group of the formula (IV): 
 
 
 
        -X²¹-E²¹-X²⁵-R³²-   (IV) 
 
 
 
wherein X²¹ is a covalent bond, an oxygen atom or an alkylene glycol group having from 1 to 6 carbon atoms, E²¹ is -CONH- (provided that in this case, X²¹ is a covalent bond, and E²¹ forms an urethane bond together with X²⁵) or a bivalent group derived from a diisocyanate selected from the group consisting of saturated aliphatic, alicyclic and aromatic diisocyanates (provided that in this case, X²¹ is an oxygen atom or an alkylene glycol group having from 1 to 6 carbon atoms, and E²¹ forms an urethane bond together with X²¹ and X²⁵), X²⁵ is an oxygen atom or an alkylene glycol group having from 1 to 6 carbon atoms, and R³² is a linear or branched alkylene group having from 1 to 6 carbon atoms; 
   Each of S¹ and S² independently represents a group of the formula (V):
       
 wherein each of R²³, R²⁴, R²⁵, R²⁶, R²⁷ and R²⁸ independently represents an alkyl group having from 1 to 3 carbon atoms or a phenyl group, K is an integer of from 1 to 50, and L is an integer of from 0 to (50-K); 
   U² is a group of the formula (VI): 
 
 
 
        -R³⁷-X²⁷-E²⁴-X²⁸-R³⁸-   (VI) 
 
 
 
wherein each of R³⁷ and R³⁸ independently represents a linear or branched alkylene group having from 1 to 6 carbon atoms, each of X²⁷ and X²⁸ independently represents an oxygen atom or an alkylene glycol group having from 1 to 6 carbon atoms, and E²⁴ is a bivalent group derived from a diisocyanate selected from the group consisting of saturated aliphatic, alicyclic and aromatic diisocyanates (provided that in this case, E²⁴ forms an urethane bond together with X²⁷ and X²⁸); 
   U³ is a group of the formula (VII): 
 
 
 
        -R³³-X²⁶-E²²-X²²-   (VII) 
 
 
 
wherein R³³ is a linear or branched alkylene group having from 1 to 6 carbon atoms, X²² is a covalent bond, an oxygen atom or an alkylene glycol group having from 1 to 6 carbon atoms, X²⁶ is an oxygen atom or an alkylene glycol group having from 1 to 6 carbon atoms, and E²² is -CONH- (provided that in this case, X²² is a covalent bond, and E²² forms an urethane bond together with X²⁶) or a bivalent group derived from a diisocyanate selected from the group consisting of saturated aliphatic, alicyclic and aromatic diisocyanates (provided that in this case, X²² is an oxygen atom or an alkylene glycol group having from 1 to 6 carbon atoms, and E²² forms an urethane bond together with X²² and X²⁶); and 
   n is an integer of at least 1; and (B) an alkyl (meth)acrylamide, wherein the weight ratio of the polysiloxane macromonomer to the alkyl (meth)acrylamide is from 10:90 to 90:10.