baber/WOPTO huggingface dataset:
Patent LV-13389-B (LV)
Title: Electricity supplying device for incandescent lamps of railway cars
Inventor: PETROVS SERGEJS
Filed: 2005-09-23
Abstract: This invention relates to the electricity supplying devices of incandescent lamps that are used in the cars of railway transport. The purpose of the invention is to improve the degree of reliability aiming to limit the voltage in incandescent lamps supplied from an overvoltaged accumulator battery, as well as reduction of heat emitted through voltage suppressor. The set purpose is reached by the following: incandescent lamps (1) are connected to the output terminal of voltage stabilizer (3) via the closing contact (1-2) of contactor (2); the input terminal of the reducing voltage stabilizer (3) via the automatic switch (4) and the isolation diode (5) is connected to the accumulator battery (6) and to rectifier (7) of generator (8). The incandescent lamps (1) via the closing contact (9-1) of reserve contactor (9) and reserve automatic switch (10) are connected to accumulator battery (6). The coils of contactors (2, 9) are connected to stabilizer (3) with one pole, and the second pole is connected to the respective automatic switches. The double-type light-emitting diode indicator (11) is connected to the stabilizer.
Patent LV-14091-B (LV)
Title: Flow-through electrical heater
Inventor: MILNIKOVS ANDREJS
IPC: F24H1/20
Filed: 2008-07-16
Abstract: The invention pertains to flow-through electrical heater for conducting liquid, consisting of a hermetically sealed body with installed therein at least one line electrode and at least one neutral electrode and fittings for inlet and outlet of conducting liquid. Said electrodes are dielectrically isolated mutually and from the body, and the neutral electrode is situated between the line electrode and the body and totally encases said line electrode.
Patent LV-14462-B (LV)
Title: A combination medicinal product for inhibition of platelet aggregation
Inventor: KALVIŅŠ Ivars
IPC: A61K31/205
Filed: 2010-06-21
Abstract: A synergistic combination medicinal product having increased activity in prophylaxis of platelet aggregation and/or thrombi formation, consisting of an effective amount of nicotinic acid or pharmaceutically acceptable salt thereof and an effective amount of meldonium or pharmaceutically acceptable salt thereof.
Patent LV-11156-B (LV)
Title: Flexible packaging material and use of such material for making containers with good air penetrability
Inventor: ROSEN AKE
IPC: B32B7/02
Filed: 1993-09-24
Abstract: Flexible packaging material in sheet or strip form for making into liquid containers with good oxygen tight properties, comprises a skeletal layer (11) composed of a mixture of plastics and filler, and a barrier layer (12) secured thereto by surface fusion when the layers are co-extruded. The layer (12) is composed of two plastics components, one of which is the same as that of the skeletal layer.
Patent ME-00524-B (ME)
Inventor: KOHL BERNHARD
IPC: C07D213/75
Filed: 2004-03-08
Abstract: Pronalazak se odnosi na nove postupke za dobijanje roflumilasta sa visokom čistoćom. Postupak obuhvata reakciju 4-amino-3,5-dihloropiridin anjona (l) sa aktivnim derivatom 3-ciklopropilmetoksi-4-difluorometiksibenzojeve kiseline (2), naznačen time, što je molarni odnos upotrebljenog 4-amino-3,5-dihloropiridin anjona na aktivni derivat 3-ciklopropilmetoksi-4-difluorometoksibenzojeve kiseline najmanje 1.5, a najviše 3, poželjno najmanje 1.8, a najviše 2.7,posebno poželjno najmanje 2, a najviše 2.5 i naročito poželjno 2.2.
Patent NO-149847-B (NO)
Title: Fremgangsmaate for fremstilling av polymerer av konjugerte diener eller kopolymerer av konjugerte diener enten seg imellom eller med en vinylaromatisk komponent
Inventor: ZARAUZ YVES DE
IPC: C08F4/00
Filed: 1976-02-27
Abstract: Fremgangsmåte for fremstilling av polymerer av konjugerte diener eller kopolymerer av konjugerte diener enten seg imellom eller med en vinylaromatisk komponent.
Patent NO-151693-B (NO)
Inventor: GOERANSSON ROLF ERIK
IPC: E04C2/04
Filed: 1982-01-06
Abstract: There is proposed a method for producing a multi-layer building element comprising a relatively thick slab-like part [4] having a first density, and a relatively thin slab-like part [1, 6] having a second density arraged on one or both sides of the relatively thick slab-like part [4] having said first density, the second density being higher than the first density. The slabs comprise a form-stable, but still uncured aerated concrete cut from one or more porous blocks of uncured aerated concrete and are lifted with the aid of suction and lifting means and moved to a support means [2], where they are stacked completely or partially one upon the other in a sequence corresponding to the desired structure of the building element to be formed. The slab layers are bonded together with a mass [3, 10] containing a hydraulic binder arranged in layers between the superposed slabs. Subsequent to forming a sandwich building element in this way, the element is charged to an autoclave and steam-cured therein.
Patent NO-154082-B (NO)
Inventor: THOENY RIET
IPC: B60G17/04
Filed: 1982-08-20
Abstract: 1. Level-regulating valve for load-dependent pneumatic suspension units in vehicles, with a double seat valve (15, 23, 35) arranged in a housing (20), which double-seat valve (15, 23, 35) connects an external pneumatic suspension bellows (5) to an external air-supply reservoir (2) via an inlet valve (15, 23) and to atomsphere via an outlet valve (15, 35), with the inlet valve seat (23) being designed in the shape of a sleeve and arranged axially adjustably in the housing (20), an a hollow actuating plunger (7 ; 24), which ist axially displaceable in the housing (20), having on one end the outlet valve seat (35), being connected via a follower (12, 25) to an actuating lever (6) and, with the actuating lever (6) in the neutral position, holding the double-seat valve (15, 23, 35) in the closed position, characterized in that the inlet valve seat (35) can be adjusted by a screw-in cover (21), which is arranged on the end face of the housing (20), and against a spring (28) supported on the housing, and that a connection (32) arranged on the housing (20) radially to the housing axis, a channel (34) made in the screw-in cover (21) and an annular groove (33) connecting the connection (32) and the channel (34) are available for connecting to the air-supply reservoir (2).
Patent NO-154204-B (NO)
Inventor: MOLDENHAUER HERMANN
IPC: F16K31/06
Filed: 1983-01-18
Abstract: 1. A multiple-way valve, especially for use in dialyzers, comprising a valve body having inlet and outlet passages (2, 22, 32, 42 or 3a, 3b, 23a, 23b, 33a, 33b, 43a, 43b, respectively) provided therein, and having secured thereto two diaphragms (4, 5) of equal effective surface at the outer edges thereof in such a way that, between one surface of one of the diaphragms ans one surface of the valve body, a valve chamber (6, 7) is formed, and that, on at least one of the diaphragms a valve plate (4a, 5a) is arranged, said valve plate opposing a valve seat (6a, 7a) arranged in at least one of the valve chambers, through which valve seat said valve chamber is adapted to be connected with an outlet passage, whereby both diaphragms are connected with one another through a mechanic coupling device (8, 28, 38a, 48 to 52) which is rigid in its direction of movement, tne connection being such that the diaphragms move in opposite directions relative to the valve chambers, and whereby an actuator (10) for displacing the diaphragms is provided, characterized in that the two valve chambers (6, 7) are connected with one another and with a common inlet passage (2, 22, 32, 42), that the diaphragms (4, 5) as well as the valve plate or plates (4a, 5a) are formed as closed components, that each of the valve plates (4a, 5a) is integral with the diaphragms associated therewith, and that the coupling device (8, 28, 38a, 48 to 52) is arranged externally of the valve chambers (6, 7) and of the inlet and outlet passages (2, 22, 32, 42 or 3a, 3b, 23a, 23b, 33a, 33b, 43a, 43b, respectively).
Patent NO-166354-B (NO)
Inventor: COOPER PAUL V
IPC: B01F27/91
Filed: 1985-07-09
Abstract: An impeller assembly is disclosed which is arranged to produce linear flow of fluid which prohibits radial flow of that fluid. An impeller is surrounded by a hollow cylindrical section mounted and fixed to the periphery of the impeller blades. The cylindrical section may extend either beyond the leading edges of the impeller blades or beyond the trailing edges of the impeller blades, or both, along the axis of rotation of the impeller assembly.
Patent NO-173666-B (NO)
Inventor: WECKHERLEN WERNER
IPC: D21B1/02
Filed: 1989-01-27
Abstract: Bulk vegetable material, especially bulk material in the form of wood chips, is conditioned for the manufacture of cellulose pulp in a silo (2) by means of steam. The steam must be introduced into the wood chips under strict temperature accuracy and distributed as freely and uniformly as possible. 
<??>To this end, the steam inlet nozzles (15) are so arranged at different points in the silo (2) that they are distributed with a high degree of uniformity and are shielded to prevent blockage by the bulk material. 
<??>The equipment is particularly intended for the conditioning of vegetable chips, especially of wood chips, for the manufacture of cellulose pulp or predominantly fibres for the production of paper and cardboard as well as the manufacture of fibre board. 
<IMAGE>
Patent NO-173500-B (NO)
Inventor: TURCONI MARCO
IPC: C07D451/12
Filed: 1990-02-05
Abstract: Pharmacologically active benzofused-N-containing heterocycle derivatives are described as muscarinic receptor blocking agents useful for the treatment of gastrointestinal and respiratory tract disorders of the following formula: <CHEM>  wherein  R represents H or C1-6 alkyl; R1 and R2 represent H, halogen, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylthio, C1-6 alkoxycarbonyl, carboxyl, hydroxy, nitro, cyano, optionally C1-4 alkyl mono- or disubstituted carbamoyl, optionally C1-4 alkyl mono- or disubstituted amino, C1-6 acylamino, C1-4 alkoxy carbonylamino, C1-6 alkylsulphynyl, C1-6 alkylsulphonyl, C1-6 acyl;  R3 represents H, C1-6 alkyl, aryl, aralkyl or it may be absent;  A represents CO, C = S, S -> O or <CHEM> B represents nitrogen when R3 is absent and the B-D bond is single, or it is carbon;  D represents CO, CH2-CH2, <CHEM> when the B-D bond is single, or D is C-R when the D-B bond is double, in which R4 represents H, C1-6 alkyl, aryl, aralkyl, hydroxy, C1-4 alkoxy and R5 represents H;  X represents oxygen, N-R or it is absent;  Y represents a basic group selected from: <CHEM> in which n is 2 or 3; p is 0 or 1 at the same time or not; q is 0, 2 or 3; R6 and R7 may be at the same time or not H, C1-4 alkyl, aralkyl or, when R7 is H or C1-4 alkyl, R6 may be <CHEM>  in which R8 represents H, C1-4 alkyl or amino. The processes for the preparation of the compounds of formula (I) as well as pharmaceutical compositions containing them are also described.
Patent NO-173868-B (NO)
Inventor: BOTANNET BERNARD
IPC: C07D303/22
Filed: 1990-05-22
Abstract: Process for the preparation of an aromatic ether of general formula: 
<IMAGE>
 by reaction of 3-chloro-1,2-propanediol sulphate with a phenol of general formula:
 Ar-OH
 in the presence of an inorganic base. 
<??>Use of the product obtained by this process for the preparation of adrenergic  beta -blockers.
Patent NO-171426-B (NO)
Inventor: BAKKE ASBJOERN
IPC: F16H61/30
Filed: 1990-11-15
Abstract: PCT No. PCT/NO91/00142 Sec. 371 Date May 13, 1993 Sec. 102(e) Date May 13, 1993 PCT Filed Nov. 14, 1991 PCT Pub. No. WO92/08914 PCT Pub. Date May 29, 1992.A gear shift device for gear boxes for vehicles, comprising at least one pair of mutually connected, double-acting hydraulic cylinders (1,2), where the pair consists of a master cylinder (1) and a slave cylinder (21). The master cylinder can be operated via a gear lever and the slave cylinder moves a mechanism which is connected to gear selector carriers in the gearbox. According to the invention each end section of the master cylinder's (1) piston (4) has an outer (54 or 55) and an inner (56 or 57) piston sealing ring which are arranged at intervals, calculated in the piston's longitudinal direction, and in these end sections there is provided a drilling (52 or 53) whose first end leads into the piston surface between the respective end sections outer and inner sealing rings (54, 56 and 55, 57 respectively), and whose second ends leads into the adjacent end face of the piston (4). Further, in each channel (52, 53) is provided a non-return valve (50, 51 ) which permits fluid to flow only from the first end of the channel (52, 53) to its other end, and in the master cylinder's (1) cylinder part (2) are provided two drillings 12, 13) whose one end, when the piston is situated in a central or neutral position in the cylinder (2) leads into the cylinder wall at a point between the outer (54 or 55) and the inner (56 or 57) sealing rings, and whose other end communicates with a fluid reservoir.
Patent NO-179417-B (NO)
Inventor: FARNSTRAND PER-AAKE
IPC: D21C9/16
Filed: 1992-10-29
Abstract: PCT No. PCT/SE91/00178 Sec. 371 Date Oct. 2, 1992 Sec. 102(e) Date Oct. 2, 1992 PCT Filed Mar. 7, 1991 PCT Pub. No. WO91/17306 PCT Pub. Date Nov. 14, 1991A method of bleaching chemical pulp in a sequence comprising at least four bleaching steps with final bleaching in a first and a second chlorine dioxide step. Between the chlorine dioxide steps an alkaline extraction is carried out, and washing takes place between the first chlorine dioxide step and extraction. Immediately after said washing step, NaOH is charged in an amount of 4-10 kg/ton pulp. Thereafter an oxidizing agent is admixed in an amount of at maximum 2 kg/ton pulp. After 15-120 seconds an acid is added for terminating the oxidation treatment and for lowering the pH-value, but without effecting a complete neutralization of residual alkaline.
Patent SE-317968-B (SE)
Inventor: USKOKOVIC M
IPC: C07C309/66
Filed: 1965-03-29
Abstract: The invention comprises a process for preparing 3 - keto - 4 - dehydro - and 3 - keto - 1, 4 - bisdehydro - 9b , 10a  - steroids of the androstane and pregnane series by condensing a 9b , 10b  - des - A - androstan - or pregnan - 5 - one with a C1- 6 alkyl vinyl ketone or a C1- 6 alkyl ethynyl ketone.
Patent SE-341559-B (SE)
Inventor: HETZEL M
IPC: G04B43/00
Filed: 1967-05-26
Abstract: 1,138,135. Electric timepieces. CENTRE ELECTRONIQUE HORLOGER S.A. May 22, 1967 [May 27, 1966], No.23674/67. Heading G3T. In an electric timepiece having a mechanical resonator, such as a torsion oscillator or tuning fork 1 serving as a frequency standard and/or driving member, normally oscillating in a plane, the amplitude of any oscillation of the resonator 1 perpendicular to that plane is limited by stop members 6, 7 extending into recesses 4,5 in the resonator 1, and at least parts of which are movable by the resonator 1 parallel to the normal plane of oscillation of the resonator when the latter engages said members 6,7. The members 6, 7 may comprise flexible pins each embedded at one end in a fixed part 2 or 3 of the timepiece. Alternatively the pins 6,7 may be replaced by balls or rollers loosely held in supports extending into the recesses 4, 5.
Patent SE-309033-B (SE)
Inventor: OLDHAM W
IPC: C07C7/00
Filed: 1964-06-18
Abstract: Alkyl benzenes, e.g. having 8 to 18 carbon atoms in the side chain are purified by contacting with benzene and either aluminium chloride or a liquid aluminium chloride-hydrocarbon complex in the presence of anhydrous hydrogen chloride or an alkyl chloride.  The liquid aluminium chloride hydrocarbon complex may be formed from the alkyl benzene to be purified or the starting reagents used to prepare the alkyl benzene.  The purification may take place for 0.1 to 5.0 hours at 0 DEG  to 100 DEG  C. using a mole ratio of benzene to alkyl benzene of 0.1 : 1 to 10 : 1 and 0.05 to 20% by weight of aluminium chloride or aluminium chloride hydrocarbon complex based on the alkyl benzene used. Sufficient hydrogen chloride may be used to saturate the hydrocarbon layer at atmospheric pressure which is separated from the liquid aluminium chloride hydrocarbon complex, washed with water, alkali, or treated with clay or silica gel and then fractionally distilled at less than 300 DEG  C. to separate off the benzene from the alkyl benzenes.  The aluminium chloride hydrocarbon complex may be recycled.
Patent RS-50403-B (RS)
Inventor: KLEEMANN HEINZ-WERNER
IPC: A61K31/4418
Filed: 2001-11-17
Abstract: Jedinjenja formule I naznačena time, što u njiima znače: Al, A2, A3, A4, A5, A6, A7 i A8 grupa nezavisno jedna oddruge azot, CH ili CR5, pri čemu najmanje četiri od ovih grupa znače CH; R(l) C(O)OR(9), SO2R(10), COR(l 1), C(O)NR(12)R(13) ili C(S)NR(12)R(13); R(9), R(10), R(l 1) i R(12) ostatak nezavisno jedan od drugog CxH2x-R(14); x 0,1,2,3 ili 4, pri tome x ne moze da bude 0, kada R(14) znaci OR(15) ili SO2Me; R(14) alkilni ostatak sa 1, 2, 3, 4, 5 ili 6 C-atoma, cikloalkilni ostatak sa 3, 4, 5, 6, 7, 8, 9, 10 ili 11 C-atoma, CF3, C2F5, C3F7, CH2F, CHF2, OR(15), SO2Me, fenil, naftil, bifenilil, furil, tienil ili neki heteroaromat koji sadrži N i ima 1, 2, 3, 4, 5, 6, 7, 8 ili 9 C-atoma, pri čemu fenil, naftil, bifenilil, furil, tienil i heteroaromat koji sadrži N, nisu supstituisani ili su supstituisani sa 1, 2 ili 3 supstituenta izabrana iz grupe koju čine F, Cl, Br, J, CF3, OCF3, NO2, CN, COOMe, CONH2, COMe, NH2, OH, alkilni ostatak sa 1, 2, 3 ili 4 C-atoma, alkoksi ostatak sa 1, 2, 3 ili 4 C-atoma, dimetilamino, sulfamoil, metilsulfonil i metilsulfonilamino; R(15) alkilni ostatak sa 1, 2, 3, 4 ili 5 C-atoma, cikloalkilni ostatak sa 3,4, 5 ili 6 C-atoma, CF3, ili fenil, koji nije supstituisan ili je supstituisan sa 1, 2 ili 3 supstituenta izabrana iz grupe koju čine F, Cl, Br, J, CF3, N02, CN, COOMe, CONH2, COMe, NH2, OH, alkilni ostatak sa 1, 2, 3 ili 4 C-atoma, alkoksi ostatak sa 1, 2, 3 ili 4 C-atoma, dimetilamino, sulfamoil, metilsulfonil i metilsulfonilamino ; R(13) vodonik, alkilni ostatak sa 1, 2, 3 ili 4 C-atoma ili CF3; R(2) vodonik, alkilni ostatak sa 1, 2, 3 ili 4 C-atoma ili CF3; R(3) CyH2y-R(16); y 0,1,2,3 ili 4,pri tome y ne može da bude 0, kada R(16) znači OR(17) ili SO2Me; R(16) alkilni ostatak sa 1, 2, 3, 4, 5 ili 6 C-atoma, cikloalkilni ostatak sa 3, 4, 5, 6, 7, 8, 9, 10 ili 11 C-atoma, CF3, C2F5, C3F7, CH2F, CHF2, OR(17), SO2Me, fenil, naftil, furil, tienil ili neki heteroaromat koji sadrži N i ima 1, 2, 3, 4, 5, 6, 7, 8 ili 9 C-atoma, pritome fenil, naftil, furil, tienil i heteroaromat koji sadrži N, nisu supstituisani ili su supstituisani sa 1, 2 ili 3 supstituenta izabrana iz grupe koju čine F, Cl, Br, J, CF3, OCF3, NO2, CN, COOMe, CONH2, COMe, NH2, OH, alkilni ostatak sa 1, 2, 3 ili 4 C-atoma, alkoksi ostatak sa 1, 2, 3 ili 4 C-atoma, dimetil-mino, sulfamoil, metilsulfonil i metilsulfonilamino; R(17) vodonik, alkilni ostatak sa 1, 2, 3, 4 ili 5 C-atoma, cikloalkilni ostatak sa 3, 4, 5 ili 6 C-atoma, CF3, fenil ili 2-, 3- ili 4- piridil, pri tome fenil ili 2-, 3- ili 4- piridil nisu supstituisani ili su supstituisani sa 1, 2 ili 3 supstituenta izabrana iz grupe koju cine F, Cl, Br, J, CF3, OCF3, NO2, CN, COOMe, CONH2, COMe, NH2, OH, alkilni ostatak sa 1, 2, 3 ili 4 C-atoma, alkoksi ostatak sa 1, 2, 3 ili 4 C-atoma, dimetilamino, sulfamoil, metilsulfonil i metilsulfonilamino; ili R(3) CHR(18)R(19); R(18) vodonik
Patent ZA-802603-B (ZA)
Title: Process for removing triorganophosphine from a liquid composition
Inventor: GALLEY R
IPC: C07F9/50
Filed: 1980-04-30
Abstract: Process for removing triorganophosphine from a rhodium-contaiing composition which is based on the reaction of phosphines with  alpha - beta  unsaturated compounds.
Patent ZA-828155-B (ZA)
Title: Process and device for the remote transmission of signals and application to the detection and/or measurement of the quantity of combustible gas in an atmosphere
Inventor: BOUTONNAT MAURICE
IPC: E21F17/18
Filed: 1982-11-05
Abstract: A process of remote transmission of signals issued by at least one sensor over a transmission line, wherein the power necessary to supply the sensor is transmitted by that line in the form of an alternating current signal of approximately constant intensity, and wherein the line fulfills the triple function of supplying power to that sensor, of transmitting interrogation signals from a central station to that sensor and of transmitting data signals in response to that interrogation signal from the sensor to the central station. A device for incorporating this process is also disclosed.
Patent ZA-844108-B (ZA)
Title: Microorganisms of the genus pseudomonas and process for the degradation of compounds containing methyl groups in aqueous solutions
Inventor: GHISALBA ORESTE
IPC: C02F3/34
Filed: 1984-05-30
Abstract: 1. Claims for Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE Facultatively methylotrophic, DMF-degrading microorganisms of the genus Pseudomonas selected from the group of the following strains : DMF 3/3 (NRRL-B-15358), DMF 3/4 (NRRL-B-15359), DMF 3/5 (NRRL-B-15360), DMF 3/6 (NRRL-B-15361), DMF 3/11 (NRRL-B-15362), DMF 3/12 (NRRL-B-15363), DMF 4/4 (NRRL-B-15364), DMF 5/3 (NRRL-B-15365), DMF 5/5 (NRRL-B-15366), DMF 5/7 (NRRL-B-15367), DMF 5/8 (NRRL-B-15368), DMF 5/9 (NRRL-B-15369) and DMF 5/10 (NRRL-B-15370), the mixed culture DMF/HW 1-5 (NRRL-B-15371), a mutant derived from these microorganisms, or mixed cultures thereof, for the purification of industrial waste waters, characterised in that, in aqueous solution, they are able to degrade dimethylformamide, formamide, methyl- or ethyl-formamide, acetamide, methanol, ethanol, saccharides, lower alkanoates, methyl-, ethyl-, dimethyl- or trimethylammonium halides, dimethyl phosphite, trimethyl phosphite, hydantoin, creatine, creatinine, barbituric acid, choline, betaine, sarcosine, dimethylglycine, glycine, glyoxylic acid, N-formylamino acids, N-acetylamino acids, acetonitrile or isobutyronitrile or mixtures of these compounds, with an increase in the biomass. 1. Claims for Contracting State : AT A process for the microbiological purification of aqueous solutions containing dimethylformamide, formamide, methyl- or ethyl-formamide, acetamide, methanol, ethanol, saccharides, lower alkanoates, methyl-, ethyl-, dimethyl- or trimethyl-ammonium halides, dimethyl phosphite, trimethyl phosphite, hydantoin, creatine, creatinine, barbituric acid, choline, betaine, sarcosine, dimethylglycine, glycine, glyoxylic acid, N-formylamino acids, N-acetylamino acids, acetonitrile or isobutyronitrile or mixtures of these compounds, characterised in that there is cultured in such an aqueous solution a microorganism of the genus Pseudomonas selected from the group of the following strains : DMF 3/3 (NRRL-B-15358), DMF 3/4 (NRRL-B-15359), DMF 3/5 (NRRL-B-15360), DMF 3/6 (NRRL-B-15361), DMF 3/11 (NRRL-B-15362), DMF 3/12 (NRRL-B-15363), DMF 4/4 (NRRL-B-15364), DMF 5/3 (NRRL-B-15365), DMF 5/5 (NRRL-B-15366), DMF 5/7 (NRRL-B-15367), DMF 5/8 (NRRL-B-15368), DMF 5/9 (NRRL-B-15369) and DMF 5/10 (NRRL-B-15370), or a mutant derived from these microorganisms, or mixed cultures thereof, in the presence of essential inorganic salts and optionally a nitrogen source, at from approximately 20 degrees C to approximately 40 degrees C and at a pH of from approximately 4 to approximately 7.5, under aerobic conditions, and, if desired, the resulting biomass is isolated.
Patent ZA-854116-B (ZA)
Title: Sustained release pharmaceutical composition for oral administration
Inventor: HARRISON PAUL JONATHAN
IPC: A61K9/58
Filed: 1985-05-30
Abstract: A pharmaceutical composition of a medicament, such as a 5-(pyridinyl)-2(IH) pyridone, in sustained release unit dosage form for oral administration. The composition is in the form of beads within a capsule of gelatin or the like. Each bead comprises an inert particulate core having adhered thereto a coating of particles of the medicament. This coating is in turn surrounded by a sustaining coating of three different polymers with different solubility profiles to allow a sustained release of the medicament both in the low pH environment of the stomach and at a higher pH values prevailing in the intestine.