baber/WOPTO huggingface dataset:
Patent IL-145602-A0 (IL)
Title: Pharmaceutical compounds
IPC: A61K31/431
Filed: 2000-04-11
Abstract: Compounds or their salts having general formulas (I) and (II) wherein: s=is an integer equal to 1 or 2, preferably s=2; b0=0 or 1; A is the radical of a drug and is such as to meet the pharmacological tests reported in the description, C and C<SUB>1 </SUB>are two bivalent radicals. The precursors of the radicals B and B<SUB>1 </SUB>are such as to meet the pharmacological test reported in the description.
Patent IL-154536-A0 (IL)
Title: Immunoregulatory compounds and derivatives and methods of treating diseases therewith
IPC: A61P1/04
Filed: 2001-08-28
Abstract: The invention provides an active pharmaceutical ingredient comprising a compound of Formula II:   
where R 9 , R 10  and R 11  are independently selected from hydrogen and C 1  to C 4  alkyl; and R 12  is selected from hydrogen and -C(O)R 13 , where R 13  is a C 1  to C 6  alkyl or an aryl group; or an ester or a pharmaceutically acceptable salt of such compound, in admixture with pharmaceutical diluent or carrier, for use in the treatment of an inflammatory condition of the gastrointestinal tract in a subject in need of such treatment. The invention also provides for the use of the said active pharmaceutical ingredient in the manufacture of a medicament for use in the treatment of an inflammatory condition of the gastrointestinal tract in a subject in need of such treatment.
Patent IL-155366-A0 (IL)
Title: Casing for firearms
IPC: F41C23/16
Filed: 2003-04-10
Abstract: A casing for firearms, comprising a metal sleeve (15) on which is stably applied, through attachment means, a barrel (12), an inner element (14) made from polymeric material for the anchoring of said sleeve (15) and an outer shell (13) made from polymeric material, is realised through successive overmouldings in sequence of the inner element (14) on the sleeve (15) to form a sleeve - inner element group (11) and then of the shell (13) on the group (11) to form the casing (10). <IMAGE>
Patent IL-161670-A0 (IL)
Title: Thymosin alpha 1 peptide/polymer conjugates
IPC: A61K38/22
Filed: 2002-11-01
Abstract: A pharmaceutical composition includes a physiologically active conjugate including a Thymosin alpha 1 (TA1) peptide conjugated to a material which increases half-life of the TA1 peptide in serum of a patient when the conjugate is administered to a patient. The material may be a substantially non-antigenic polymer. In a method of the invention, the substantially non-antigenic polymer is conjugated to a TA1 peptide. Compositions according to the invention are administered to patients in need of immune stimulation.
Patent IL-162612-A0 (IL)
Title: Tracking system using fixed opticalradiators
IPC: G01S1/70
Filed: 2004-06-17
Abstract: Apparatus for tracking an object (12A, 12B, 12C) including radiator modules (16A, 16B, 16C), disposed in an array of known locations adjoining a region (13) in which the object moves; each module includes at least one emitter (44, 46, 48) which emits a respective color selected from among a first plurality of colors. The apparatus includes a controller (32), which drives the at least one emitter to emit during a respective time slot, selected from among a second plurality of time slots during which the modules may emit. The apparatus also includes a location unit (22), fixed to the object and including at least one camera (72), which captures a sequence of electronic images containing some of the locations of the modules. The apparatus further includes a processing unit (26), which processes the electronic images to determine, responsively to the colors emitted by the modules and the time slots in which the colors are emitted, a location of the object.
Patent IL-163852-A0 (IL)
Title: Rs7 antibodies
IPC: A61K51/10
Filed: 2003-03-03
Abstract: This invention relates to an immunoconjugate comprising (i) a humanized antibody comprising the heavy chain CDR (complementarity determining region) sequences CDR1 (NYGMN); CDR2 (WINTYTGEPTYTDDFKG) and CDR3 (GGFGSSYWYFDV), and the light chain CDR sequences CDR1 (KASQDVSIAVA); CDR2 (SASYRYT); and CDR3 (QQHYITPLT) and human antibody framework region (FR) sequences, wherein the FR sequences comprise substituted murine amino acid residues found at a corresponding location in amino acid residues 38, 46, 68 and 91 of the murine heavy chain variable region of Fig. 3B and amino acid residue 20, 60, 85 and 100 of the murine light chain variable region of Fig 3A, wherein the humanized antibody is conjugated to (ii) a drug.
Patent IL-181910-A0 (IL)
Title: Use of 2-phenyl-1,2-ethanediol-(di) carbamates for treating epileptogenesis and epilepsy
Filed: 2007-03-13
Abstract: This invention is directed to methods for preventing, treating, reversing, inhibiting or arresting epilepsy and epileptogenesis in a subject comprising administering to the subject in need thereof a therapeutically effective amount of a compound selected from the group consisting of Formula (I) and Formula (II), or a pharmaceutically acceptable salt or ester thereof: wherein phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and, R1, R2, R3, R4, R5 and R6 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
Patent IL-187188-A0 (IL)
Title: Improved human interferon molecules and their uses
Filed: 2007-11-06
Abstract: Modified human interferon polypeptides and uses thereof are provided, including PEGylated human interferon polypeptides with one or more non-naturally encoded amino acids.
Patent IL-187994-A0 (IL)
Title: Automatic squeezing machine
Filed: 2007-12-09
Abstract: A squeezing machine whose actual squeezing element is formed mainly of a cone or rotating head which, apart from the rotating movement, has upward or downward movement depending on the point in the squeezing operation, on which there is a set of blades in the form of fins in such a way that the fruit is deposited on said blades and when these are pushed by the rotating cone in its upward path exert pressure on the fruit, slicing this vertically and guiding it towards the cone for crushing the pulp, as the fruit cannot escape through being trapped in the recess inside a dome that may consist of two parts, one of them moving, in such a way that as it moves it leaves open a hole communicating the squeezing element with a bin containing the fruit to be squeezed, allowing in a fruit previously aligned with said hollow by means of a pulling system.
Patent IL-229124-A0 (IL)
Title: Inhibitors of the mutant form of kit
IPC: A61K31/506
Filed: 2013-10-28
Abstract: The present invention relates to the treatment of KIT dependent diseases that are characterized by a mutant form of KIT whereby the mutant KIT is identified and an appropriate inhibitor of the mutant KIT is administered.
Patent RO-126976-A0 (RO)
Title: Method and program-product for the optimization of the chemotherapy administration activity
Inventor: TODOR NICOLAE
IPC: G06Q50/00
Filed: 2011-03-21
Abstract: The invention relates to a method and program-product for the optimization of the chemotherapy administration activity. The claimed method is based on a core comprising two databases, a database consisting of a patient's personal data and previous treatments and a knowledge database consisting of all the chemotherapy schemes and all the details and medical and non-medical restrictions; at each patient's examination, the chemotherapist analyses the results of previous treatments, on the basis of the database information, selects from the knowledge database a treatment scheme which he makes fit for the patient's conditions at the moment of the examination and makes a prescription to the pharmacy, which delivers the medication, and thus the treatment is started. The claimed program product comprises a plurality of interconnected modules which operate with data from several databases, a database which comprises a catalogue of users', a database for the prescriptions, a knowledge database, a database with ICD codes, a database with histology codes, a database which comprises a catalogue of the nurses, a database comprising a catalogue of the residents, a database comprising a catalogue of health insurance companies whereto the patients subscribed and a database which comprises a catalogue of trials used by patients in administering the chemotherapy; three categories of users have access to said databases: the administrator having the right of modifying the data in all the databases with the exception of the database of prescriptions, the prescribing doctors with the right of modifying only the database of prescriptions and the secretariate which only has the right of consulting the database of prescription and making reports.
Patent RO-132157-A0 (RO)
Title: System for converting wind energy into electric energy
Inventor: GEANGU CONSTANTIN
IPC: F03G7/08
Filed: 2017-04-10
Abstract: The invention relates to a system for converting the wind energy into electric energy. According to the invention, the system comprises a support (1) on which a tarpaulin (2) is anchored by means of some anchoring ropes (5), on the sides of the tarpaulin (2) there being a row of magnets (3), and in front of each magnet (3), on the support (1), there being installed one or more coils (4), wherein the vibratory movement of the magnets (3) in the close proximity of the coils (4), as a result of the wind action upon the tarpaulin (2), induces in each coil (4) a variable electromotive force which generates an alternating electric current.
Patent AP-2001002224-A0 (AP)
Title: Benzoheterocycles and their use as MEK inhibitors.
Inventor: BARRETT STEPHEN DOUGLAS
IPC: C07D235/10
Filed: 1999-12-21
Abstract: The invention provides compounds having formula (I), wherein W is OH, or derivatives of the carboxylic acid, and Q is a heterocyclo-condensed ortho-phenylene residue. These compounds are useful as MEK inhibitors, particularly in the treatment of proliferative diseases such as cancer.
Patent IE-910026-A1 (IE)
Title: Treatment of protozoal diseases
IPC: A61K31/63
Filed: 1991-01-04
Abstract: The antibacterial substance baquiloprim (2,4-diamino-5-[8-dimethylamino-7-methyl-5-quinolylmethyl] pyrimidine) is shown to be active against protozoal infections, e.g. toxoplasmosis. Preferably the baquiloprim is administered together with a sulphonamide.
Patent LU-83499-A1 (LU)
Inventor: EIBL J
IPC: A61K35/16
Filed: 1981-07-20
Abstract: In a method of producing a blood-coagulation-promoting preparation based on human proteins and having a content of coagulation factors II, VII, IX and X and factor-VIII-inhibitor-bypassing-activity (FEIBA), human plasma is treated with sulphated high-polymer carbohydrates and/or with basic ion exchangers, the protein mixture with generated FEIB-activity is adsorbed on the ion exchanger, and the preparation is gained by elution and concentration.
Patent LU-85179-A1 (LU)
Title: Low flying aircraft missile system - uses multiple sensors to locate target and launches missile through tube using aircraft velocity with trajectory nearly vertical
Inventor: MAYDELL IGNAZ VON
IPC: F41G7/34
Filed: 1984-01-23
Abstract: The aircraft overflies the target at low level. A detector pivots in a plane perpendicular to the flight vector of the aircraft so that the sensors look downwards along the calculated resultant velocity of the missile after discharge. Sensors comprise a magnetic anomaly detector for large targets such as tanks, a device for detecting the electromagnetic or quasi-magnetostatic fields associated with electrical apparatus, optical and/or thermal detectors. The missile is in a fixed launch tube, inclined backwards. A tachometer measures the forward velocity of the aircraft and the missile is launched so that its resultant velocity vector points steeply downwards towards the target. Ideally the descent should be vertical but it can lie within a cone of + or -45 deg. from the vertical without loss of precision. A downwards compares the radar image with stored data of linear features such as roads so that the aircraft can navigate itself along such a feature in search of targets. For detection of moving targets, a long range sensor scans an arc of the terrain ahead of the vehicle.
Patent MA-21410-A1 (MA)
Inventor: LANCE HARKUS
IPC: E01B9/30
Filed: 1988-10-18
Abstract: A pad has a base portion 18, which lies on a foundation 16 and on which a flange 19 of a railway rail lies, and upstanding side portions 21 extending upwardly from opposite sides of the base portion 18 and formed with a recess 40 in which lies a part 41 of a rail clip 30. The pad may have sideways-extending portions 23 for projecting on opposite sides of a clip-retaining member 1 and it may also have projecting islands 36, possibly chevron-shaped, on one face or on both faces. The base portion 18 may be one member made of soft material and this may be fixed to a separate member made of harder material which is formed with the side portions 21 and the recess 40.
Patent MA-42212-A1 (MA)
Title: Joint d'étanchéité de couplage ayant des surfaces en rampe
Inventor: PARK YANG
IPC: F16L21/06
Filed: 2016-11-18
Abstract: L'invention concerne un joint d'étanchéité pour un accouplement reliant des éléments tuyaux, lequel joint a des surfaces en rampe orientées de façon angulaire sur une surface externe. Les surfaces en rampe sont disposées par paires diamétralement opposées qui sont positionnées aux positions à trois heures et à neuf heures à l'interface entre les segments formant le couplage. Les rampes sont prévues pour atténuer le pincement des joints d'étanchéité entre les segments quand les segments sont tirés l'un ver
Patent MA-43624-A1 (MA)
Title: Système et dispositif d'éclairage à del
Inventor: BREBENEL NICOLAE
IPC: H05B37/02
Filed: 2016-08-08
Abstract: Dispositif, système, processus et procédé de fabrication utilisant au moins deux sources d'éclairage à del pour fournir des modules de composants auxiliaires. Des modes de réalisation peuvent être utilisés dans diverses industries, comprenant les réverbères de ville, les systèmes d'éclairage intérieurs, les systèmes d'éclairage dans les automobiles, les systèmes d'éclairage dans les trains, les systèmes d'éclairage dans les tunnels, les systèmes d'éclairage dans les bâtiments, les systèmes d'éclairage en
Patent UY-25341-A1 (UY)
Title: Procedimiento para la preparacion de polimorfos de dofetilida
Inventor: IAN COLIN APPLEBY
IPC: C07C311/05
Filed: 1999-01-08
Abstract: La invención se refiere a procedimientos de preparación de los polimorfos de dofetilida P162, P162a y P143 prácticamente puros, que se caracteriza por calorimetría de barrido diferencial (DSC) en la que presenta un suceso térmico endotérmico a aproximademante 162ºC. El polimorfo se caracteriza por difracción con rayos X de polvo(PXRD) obtenido por irradiación con rayos X K-alfa1 de cobre, o por espectro infrarrojo (IR)como un fundido en nujol.
Patent UY-27746-A1 (UY)
Title: Comprimido masticable con sabor agradable
Inventor: KASRAIAN KASRA
IPC: A61K9/24
Filed: 2003-04-02
Abstract: Se describe aqui un comprimido masticable con sabor agradable para administración oral de dihidrocloruro de cetirizina. La formulación se hace de sabor más agradable incorporando una combinación de un agente saborizante de uva con un agente saborizante de vainilla.
Patent UY-27893-A1 (UY)
Title: Agonistas del receptor (vpac2) del peptido activante de la adenilatociclasa hipofisaria (pacap) y sus metodos de uso farmacologicos
Inventor: PAN CLARK
IPC: C07K14/705
Filed: 2003-07-11
Abstract: Esta invención provee nuevos péptidos que funcionan in vivo como agonistas del receptor VPAC2. Estos polipéptidos secretagogos de la insulina reducen más la glucosa sanguínea in vivo que los controles luego de la provocación con glucosa. Estos polipéptidos también son estables en la formulación y tienen vidas medias prolongadas. Proveen una nueva terapia para pacientes con secreción reducida de insulina endógena, en particular los diabéticos del tipo 2. La invención es un polipéptido seleccionado de un grupo específico de polipéptidos relacionados con VPAC2, o sus equivalentes funcionales. Se refiere, además, a un método de tratamiento de una enfermedad metabólica en un mamífero que comprende administrar una cantidad terapéuticamente efectiva de los péptidos secretagogos de la insulina a dicho mamífero.
Patent UY-29840-A1 (UY)
Title: Compuestos de pirimidina amida como inhibidores de pgds
Inventor: LOREN VANDEUSEN CHRISTOPHER
IPC: A61P37/00
Filed: 2006-10-04
Abstract: Esta invención se refiere a un compuestos de fórmula (I): en la que R1, R2, R3 y L1 son como se han definido anteriormente, una composición farmacéutica que comprende el compuesto, y el uso del compuesto para tratar trastornos alérgicos y/o inflamatorios, particularmente trastornos tales como rinitis alérgica, asma y/o enfermedad pulmonar obstructiva crónica (COPD)
Patent UY-30229-A1 (UY)
Title: Tetrahidro-pirimidoazepinas como moduladores de trpv1
Inventor: MERIT JEFFREY E
IPC: A61P11/14
Filed: 2007-03-21
Abstract: Se describen ciertos compuestos tetrahidro-pirimidoazepina, que son útiles como moduladores de TRPV1. Dichos compuestos pueden ser usados en composiciones farmacéuticas y métodos de tratamiento de enfermedades, trastornos y afecciones médicas intermediadas por TRPV1. Por lo tanto, los compuestos pueden ser administrados por ejemplo en dolor, prurito, tos,asma y enfermedad inflamatoria del intestino.
Patent UY-30512-A1 (UY)
Title: Nueva composicion farmaceutica
Inventor: KAPSI SHIVAKUMAR G
IPC: A61P7/00
Filed: 2007-07-27
Abstract: Se describen nuevas composiciones farmacéuticas que contienen bis-(monoetanolamina) del ácido 3´-[(2z)-[1-(e,4-dimetilfenil)-1,5-dihidro-3-metil-5-oxo-4H-pirazol-4-ilideno]hidrazino]-2´-hidroxi-{1,1´-bifenil]-3-carboxílico (eltrombopag olamina) y procesos para su preparación.
Patent UY-31248-A1 (UY)
Title: Composición farmacéutica que comprende la combinación de un agente antiandrogénico, un agente estrogénico esterídico sintético y agentes vitamínicos, útil para el control y tratamiento del acné tardío en la mujer
Inventor: OCHOA VICTOR GUILLERMO ALVAREZ
IPC: A61P17/00
Filed: 2008-07-25
Abstract: La presente invención esta relacionada con una composición farmacéutica compuesta por la combinación sinérgica de Acetato de Ciproterona, Etinilestradiol y agentes vitamícios como Palmitato de Retinol (vitamina A) y di-alfa-tocoferol (vitamina E); los cuales se encuentran formulados en una sola unidad de dosificación para ser administrada por vía oral en forma de cápsula o tableta, misma que está indicada para el control y tratamiento de enfermedades tales como: el acné tardío manifestado en la mujer y la disminución de vitamina A y E provocada por dicha enfermedad, así como otras patologías relacionadas.
Patent ZW-17786-A1 (ZW)
Title: Process for moulding articles from curable compositions
Inventor: JOHN BARNARD
IPC: B29C37/00
Filed: 1986-08-29
Abstract: A method of moulding an article having areas of colour contrast on the surface comprising coating one surface of a mould with a coloured composition prior to filling the mould with a curable composition of contrasting colour and curing the composition characterised in that the coloured composition comprises at least 25% by weight of   (a) a fluid carrier comprising a mixture of 0-l00 parts by weight of a polymerisable liquid and correspondingly l00 to 0 parts by weight of a nonpolymerisable, volatile, organic solvent, (b) from 0.l to l0% by weight of the total composition of a colourant in the form of an inorganic pigment or carbon black, or 0.000l to l% by weight of an organic pigment or dye, (c) from 0 to 60% by weight of the total composition of a finely divided filler, preferably having a mean particle size of less than 2 microns, (d) 0.l to 50%, preferably l to l0% by weight of a drying oil-modified alkyd resin soluble in the fluid carrier and (e) a preformed polymer soluble in the fluid carrier present at a concentration at least half that of the drying oil modified-alkyd resin.
Patent ES-151151-A1 (ES)
Title: PROCEDIMIENTO PARA LA OBTENCIoN DE AMIDAS áCIDAS PIRONCARBONiLICAS
Filed: 1939-12-19
Abstract: Procedimiento para la obtención de amidas-ácido-alfa-pironcarbonílicascaracterizado porque se deja reaccionar ácido alfa-pironcarbonílico o sus productos de sustituciónrespectivamente sus derivados funcionales sobre aminas secundariassus sales o halogenuros-ácidos-carbamínicos en presencia o ausencia de disolventesmedios de condensación o medios que combinan el ácido.
Patent ES-191969-A1 (ES)
Title: Nuevo aparato volador
Filed: 1950-03-06
Abstract: Nuevo aparato volador, caracterizado porque sus alas están constituidas cada una de ellas por una serie indefinida de aspas helicoidales de paso distinto y progresivo de menor a mayor desde la más alta, o primera que toma el aire, hasta la más baja o de salida del mismo, determinando el conjunto una superficie o sucesión de superficies cuya sección será una línea poligonal inscrita en una curva de tipo helicoidal, pudiendo aumentarse el número de aspas cuanto se quiera e, incluso, convertir la sucesión de todas en una verdadera superficie curva cuya sección sea la referida curva helicoidal; con lo que dichas alas, que girarán en torno a sus respectivos ejes, impulsadas por uno o varios ordinarios motores de aviación, funcionarán en dicho giro como propulsoras principalmente en las partes formadas por sus últimas aspas, y como autogiratorias y sustentadoras en las partes formadas por sus primeras aspas.
Patent ES-192621-A1 (ES)
Title: PERFECCIONAMIENTOS EN LA CONFECCIoN DE MANTILLAS A MáQUINA, IMITANDO EL ESTILO GRANADINO A MANO
Filed: 1950-04-12
Abstract: Perfeccionamientos en la confección de mantillas a máquina imitando el estilo granadino a mano caracterizados por el hecho de que sobre el tul extendido en una superficie plana se estampan las líneas del dibujo empleando para ello un patrón perforado plantilla o trepa en el que se han dibujado previamente los elementos decorativos cuya repetición simétrica constituye el bordado de la mantilla empleando para estarcir el dibujo una mezcla de polvos colorantes y petroleo o bencina procurando que el color elegido resalte sobre el fondo del tul.
Patent ES-196104-A1 (ES)
Title: UNA MONTURA PARA PuAS DE MáQUINAS TEXTILES HILADORAS HANáLOGAS
IPC: D01H7/06
Filed: 1951-01-12
Abstract: Montura para púas de las máquinas textiles de hilatura y análogas en las cuales el soporte comprende una prolongación tubular que incluye un dado elástico en el cual va sostenido un tubo que incorpora cojinetes para una púa montada en el coaxialmente; estando dicho dado situado en un punto que aproximadamente coincide con el ocupado por el centro dinámico de un paquete de hilo enrollado o sostenido en la púa siendo tal la disposición que la púa y su carga puedan girar sobre el centro del dado elástico.
Patent ES-198044-A1 (ES)
Title: UN PROCEDIMIENTO QUiMICO PARA LA OBTENCIoN DE ADHESIVOS BITUMINOSOS, APLICABLES AL ASFALTADO DE CALZADAS
Filed: 1951-05-25
Abstract: Un procedimiento químico para la obtención de adhesivos bituminosos aplicables al asfalto de calzadas caracterizado porque partiendo de un aceite de creosota pesada por ejemplo aceite residual de alquitrán preferentemente después de haber separado el ácido carbónico y las naftalinas y en algunos casos también las antracitas cuyo aceite resulta prácticamente estable a 177º C. se prepara una mezcla homogénea con resina o goma vegetal por ejemplo goma de pino o copal normalmente con un punto de fusión superior a los 121º C.