baber/WOPTO huggingface dataset:
Patent CA-2894684-A1 (CA)
Title: Conception et optimisation de systemes de crispr-cas ameliores, methodes et compositions d'enzyme pour la manipulation de sequence dans les eucaryotes
Inventor: ZHANG FENG
IPC: C12N15/63
Filed: 2013-12-12
Abstract: L'invention concerne la fabrication et l'optimisation de systèmes, de procédés et de compositions pour la manipulation de séquences et/ou d'activités de séquences cibles. Elle concerne des compositions et des procédés associés à des composants d'un complexe CRISPR, en particulier qui comprend une enzyme orthologue Cas.
Patent CA-2894860-A1 (CA)
Title: Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
Inventor: KOENIG GERHARD
IPC: A61K31/439
Filed: 2009-11-19
Abstract: (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide has been found to have procognitive effects in humans at unexpectedly low doses. Thus, (R) -7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof can be used at unexpectedly low doses improve cognition.
Patent CA-2896957-A1 (CA)
Title: Characterizing a glatiramer acetate related drug product
Inventor: SCHWARTZ RIVKA
IPC: A61K49/00
Filed: 2014-01-02
Abstract: The present invention provides a process for characterizing a glatiramer acetate related drug substance or drug product comprising the steps of: a) obtaining a batch of the glatiramer acetate related drug substance or drug product; b) immunizing a mammal with a predetermined amount of a glatiramer acetate related drug substance or drug product; c) preparing a culture of cells from the mammal of step b) at a predetermined time after immunization; d) incubating cells from the culture of step c) with a predetermined amount of the glatiramer acetate drug related substance or drug product of step a); and e) determining the level of expression of at least one gene disclosed herein or determining the level of biological activity of the cells of step c) as disclosed herein, thereby characterizing the glatiramer acetate related drug substance or drug product of step a).
Patent CA-2898104-A1 (CA)
Inventor: GRAY LEE ANTONY
IPC: A44C11/00
Filed: 2014-02-03
Abstract: An ornamental component (1860) for a bracelet and / or a necklace is disclosed. The ornamental component have a through hole (1850) allowing the ornamental component to be strung on an elongated member of a bracelet and / or necklace, said through hole defining a through hole axis. The ornamental component comprising : a self-supporting housing (1801) having a through hole comprising a first opening (1802) at a first side of the housing and a second opening (1806) at a second side of the housing; and a first tubular element (1805) having a through hole inserted in said through hole of said self-supporting housing through said first opening of said self-supporting housing. The ornamental component further comprises a locking element having a through hole inserted in the through hole of self-supporting housing through said second opening of the self-supporting housing. The locking element comprises an engagement portion attached to said first tubular element.
Patent CA-2904200-A1 (CA)
Inventor: PETTY JACK D
IPC: F23R3/00
Filed: 2013-12-03
Abstract: A gas turbine engine includes a combustor having a dual-wall impingement convention effusion combustor tile assembly. The dual-wall tile assembly provides a cooling air flow channel and attachments for securing the tile to the cold skin liner of the combustor. Cooling is more efficient in part due to the dual wall construction and in part due to reduced parasitic leakage, and the design is less sensitive to attachment features which operate at lower temperatures.
Patent CA-2904705-A1 (CA)
Inventor: SAWADA YOHEI
IPC: E04B1/64
Filed: 2015-09-16
Abstract: An exterior wall structure includes first to fourth waterproofing members. Each of the first to fourth waterproofing members includes a fixing portion, a positioning portion, a separating portion, a supporting portion, and first and second seal portions. The positioning portion extends continuously with the fixing portion toward the exterior side. The positioning portion positions an exterior wall material by coming into abutment with an end face of the exterior wall material. The separating portion extends continuously with the positioning portion toward the sash body side so as to be located between the sash body and the exterior wall material. The first seal portion inhibits the entry of water by coming into abutment with the exterior wall material. The second seal portion inhibits the entry of water by coming into abutment with the sash body.
Patent CA-2904890-A1 (CA)
Title: Compressive patient warming device
Inventor: VARGA CHRISTOPHER
IPC: A61H23/04
Filed: 2014-02-18
Abstract: A compressive patient warming device is provided. The device includes an elastic inner layer that conforms snugly to a shape of an appendage of a patient so that the inner layer wraps around and substantially contacts most of an underlying surface area of the appendage. An outer layer is attached to and covers the inner layer to form a space that holds a heat transfer medium between the inner layer and the outer layer while the inner layer is wrapped around the appendage. The outer layer may be a rigid layer, and a predetermined compressive load may be applied to the outer layer to encourage blood flow in the appendage. A source of heat may be applied to the device to maintain normothermia and/or treat hypothermia.
Patent CA-2906321-A1 (CA)
Inventor: TOBA MAYUMI
IPC: A41G5/00
Filed: 2014-03-03
Abstract: La présente invention concerne un outil d'augmentation des cheveux pour lequel un matériau linéaire (10) d'une longueur spécifiée est pourvu de deux zones à diamètre élevé à un intervalle constant et un composant de tube plastiquement déformable (18, 19) est fixé à une position proche de chacune des zones à diamètre élevé. La partie du matériau linéaire située entre les deux zones à diamètre élevé est la zone d'installation (15) et des cheveux d'imitation (20) sont fixés dans celle-ci à des positions multiples à un intervalle spécifié. Avec les vrais cheveux qui restent sur la tête étant enfilés à travers les composants de tube (18, 19), les composants de tube sont plastiquement déformés de manière à être écrasés et sont fixés aux vrais cheveux. La partie du matériau linéaire configurant la zone d'installation (15) est formée de manière à suivre la surface de la tête et est nouée à des emplacements multiples de manière à être placée dans ladite partie du matériau linéaire en utilisant les vrais cheveux situés de chaque côté. En conséquence, l'outil d'augmentation des cheveux peut être fixé à la tête avec une résistance et une stabilité suffisantes sans utiliser d'adhésif.
Patent CA-2907128-A1 (CA)
Inventor: LYNCH RONAN
IPC: B65D5/56
Filed: 2015-10-07
Abstract: A container having an opening sealed with a polymeric film, the container being formed from a pulpable, fibrous material, and less than about 50 % of the surface area of the polymeric film being is contact with the container, a method of making such a container, and a method of packaging an article of commerce (e.g., fruit) in said container.
Patent CA-2908356-A1 (CA)
Title: Hot-stamped steel, cold-rolled steel sheet and method for producing hot-stamped steel
Inventor: SUWA YOSHIHIRO
IPC: C23C2/06
Filed: 2014-03-27
Abstract: A hot-stamp-molded article according to the present invention comprises specific chemical components, wherein the relationship represented by the formula: (5×[Si]+[Mn])/[C] > 10 is satisfied in which [C], [Si] and [Mn] respectively represent the contents, in mass%, of C, Si and Mn, a ferrite and a martensite are contained respectively at area ratios of 40 to 95% inclusive and 5 to 60% inclusive, the sum total of the area ratio of the ferrite and the area ratio of the martensite is 60% or more, at least one of a pearlite at an area ratio of 10% or less, a retained austenite at a volume ratio of 5% or less and a bainite at an area ratio of less than 40% may be contained, the hardness of the martensite as measured on a nano indenter satisfies both a relationship represented by the formula: H2/H1 < 1.10 and a relationship represented by the formula: sHM < 20, and a TS×? value, which is a product of a tensile strength (TS) and a hole expansion ratio (?), satisfies 50000 MPa·% or more.
Patent CA-2912927-A1 (CA)
Inventor: REISNER COLIN
IPC: A61K9/00
Filed: 2014-05-22
Abstract: Pharmaceutical compositions, systems and methods suitable for respiratory delivery of a fixed combination of LAMA, LABA, and ICS active agents are described. The pharmaceutical compositions described herein may be formulated for respiratory delivery via a metered dose inhaler (MDI). Also described herein are MDI systems for delivery of a fixed combination of LAMA, LABA, and ICS active agents, as well as methods for preparing and using the compositions and systems described herein.
Patent CA-2915569-A1 (CA)
Inventor: PANSEGROUW BESTER JACOBUS
IPC: B60P7/06
Filed: 2014-06-13
Abstract: The invention discloses a dunnage bag arrangement for securing loads, includes an inflatable dunnage bag having a gastight inflatable bladder; and a hanger member connected to the dunnage bag and adapted to being supported on top of loads and adapted to support the dunnage bag in a void between loads. The dunnage bag includes a reinforcing sleeve made of at least one material ply, the sleeve having a first opening and a second opening, and the sleeve being folded and sealed and/or stitched to close off at least one of the openings.
Patent CA-2915968-A1 (CA)
Inventor: KIM JOSEPH H
IPC: F15B15/12
Filed: 2014-06-13
Abstract: A rotary actuator with hydraulic supply includes a housing defining a first arcuate chamber (422) comprising a cavity, a fluid port (3722) in fluid communication with the cavity, and an open end. A rotor assembly in the housing includes an output shaft (412) and a rotor arm extending radially outward from the output shaft. An arcuate-shaped piston (414) is disposed in the housing for movement in the arcuate chamber. The rotary actuator includes a fluid line is coupled to the fluid port, a high pressure fluid line (3707), a low pressure fluid line (3709), and a central pressure source (3706) coupled to the high pressure fluid line. A servo valve (3704) is positioned between the central pressure source and the rotary actuator and is controllable to selectively connect the fluid line to the high pressure fluid line and the low pressure fluid line to control movement of the rotary actuator.
Patent CA-2916455-A1 (CA)
Inventor: KAWAHARA SHUYA
IPC: H01M8/04
Filed: 2014-11-04
Abstract: In order to increase, in a short period of time, the power generation amount of a fuel battery cell when the power generation amount of a fuel battery decreases due to a reduction in the degree of humidity of the fuel battery cell, a cathode of the fuel battery cell includes a conductive material, a catalyst, and an ionomer that covers the conductive material and the catalyst. At a time (tc1), if the output voltage value (VFC) of the fuel battery is lower than a threshold voltage value (VFCTH) and the electrical resistance value (RFC) of the fuel battery is higher than a threshold resistance value (RFCTH), an oxidising gas quantity-increasing control, which increases the quantity (QOFC) of an oxidising gas to be sent to the fuel battery, is performed.
Patent CA-2917429-A1 (CA)
Title: Element chaussant
Inventor: GIRARD FRANCOIS
IPC: A43C15/06
Filed: 2016-01-12
Abstract: Elément chaussant (1) comprenant un semelage externe souple (3) et une tige souple (4), lesquels délimitent un volume de chaussage, l'élément chaussant (1) s'étendant en longueur depuis une extrémité arrière (5) jusqu'à une extrémité avant (6), en largeur entre une partie latérale (7) et une partie médiale (8), et en hauteur depuis une face externe (10) du semelage externe (3) jusqu'à une extrémité supérieure (21), l'élément chaussant présentant une ouverture de chaussage (25), l'élément chaussant comprenant des pointes (9) qui font saillie au niveau de la face externe (10) du semelage externe (3). L'élément chaussant comprend un renfort amovible (34) qui présente l'aspect général d'une plaque, le renfort (34) s'étendant en longueur depuis une extrémité arrière (35) jusqu'à une extrémité avant (36), en largeur entre un bord latéral (37) et un bord médial (38), et en épaisseur entre une face d'appui (39) et une face d'accueil (40), le renfort (34) étant disposé en regard du semelage externe (3), le renfort (34) étant sensiblement indéformable en flexion longitudinale, selon un axe transversal.
Patent CA-2917668-A1 (CA)
Inventor: LAWSON LAWRENCE J
IPC: G01L5/16
Filed: 2014-07-10
Abstract: A balancing device (10b), a uniformity device (10b) and an apparatus (10", 10" ") including the balancing device (10b) and the uniformity device (10u) are disclosed. Each of the balancing device (10b) and the uniformity device (10u) includes at least one multi-axis transducer (50b, 50b', 114a) or three or more air spring members (114ub). Methods are also disclosed.
Patent CA-2919375-A1 (CA)
Inventor: SUGDEN JOHN L
IPC: C08L23/08
Filed: 2014-08-06
Abstract: The invention provides a composition comprising at least the following components: A) an ethylene-based polymer comprising the following properties: a) a high load melt index (I21) from 10 to 100 g/10 min, b) a density from 0.940 to 0.965 g/cc; B) from 20 ppm to 120 ppm, based on the weight of the composition, of at least one fluoropolymer comprising, in polymerized form, at least one vinylidene fluoride monomeric unit and at least one hexafluoropropylene monomeric unit; C) at least one polyalkylene oxide; and D) from 500 ppm to 2000 ppm, based on the weight of the composition, of at least one metal stearate.
Patent CA-2919460-A1 (CA)
Inventor: WANG WEI
IPC: C09D7/61
Filed: 2014-07-25
Abstract: The present invention provides an aqueous polymer dispersion for vibration damping comprising a film-forming polymer in the form of dispersed particles comprising a polymer phase P1 and different polymer phases P2 and P3; the polymer dispersion obtained by free radical emulsion polymerization. Controlling the difference in glass transition temperatures of the polymers in the various polymer phases results in effective sound damping as determined by a Damping Loss Factor of at least 0.1 over a temperature range of at least 40°C. determined at a frequency of 200 Hz over a temperature range of 10 to 65°C. Use of a chain transfer agent in the polymerization of the various monomer charges results in good appearance in the resultant vibration damping coating.
Patent CA-2922518-A1 (CA)
Title: Soybean variety xb07ab15r
Inventor: Krasheninnik Nadia Nikolayevna
IPC: A01H5/10
Filed: 2016-03-03
Abstract: A novel soybean variety, designated XB07AB15R is provided. Also provided are the seeds of soybean variety XB07AB15R, cells from soybean variety XB07AB15R, plants of soybean XB07AB15R, and plant parts of soybean variety XB07AB15R. Methods provided include producing a soybean plant by crossing soybean variety XB07AB15R with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB07AB15R, methods for producing other soybean varieties or plant parts derived from soybean variety XB07AB15R, and methods of characterizing soybean variety XB07AB15R. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB07AB15R are further provided.
Patent CA-2923695-A1 (CA)
Title: Brineless, low-acid packaged olives
Inventor: SIGAL ABDULKADIR YUSSUF
IPC: A23L19/20
Filed: 2014-09-08
Abstract: The invention relates to olive processing, and includes methods for producing low-acid olives, as well as the olives produced thereby. In one aspect, the invention provides compositions directed towards packaged olive preparations having novel and beneficial characteristics, for example, olive preparations that are free of packing liquids such as brine solutions. In other aspects, the packaged olive preparations of the invention can have other beneficial properties, such as extended shelf life, have flavor infusions, and/or can be stuffed with various flavored stuffings.
Patent CA-2926485-A1 (CA)
Inventor: MURRAY STEVEN
IPC: B25G1/08
Filed: 2016-04-08
Abstract: An apparatus for bit replacement of multiple bit screwdrivers having a handle with a plurality of screwdriver bits in a circular array of longitudinal bores within a handle magazine. The apparatus includes a body having a plurality of female receptacles arranged in a circular array. Screwdriver bits are engaged with the female receptacles.  To effect a replacement, the screwdriver bits are aligned with the longitudinal bores of a multiple bit screwdriver. The body is then pressed toward the handle to urge the screwdriver bits into the longitudinal bores. Once the screwdriver bits are in place, the body is detached.
Patent CA-2932237-A1 (CA)
Title: Ionic aqueous compositions comprising sulfated polysaccharides
Inventor: ALEVIZOPOULOS KONSTANTINOS
IPC: A61K35/74
Filed: 2014-11-28
Abstract: Disclosed herein are ionic aqueous compositions useful as nasal passage washes to aid in the resorption of edema of the respiratory mucosa, e.g., the nasal mucosa, for the treatment of respiratory tract and/or respiratory mucosal-related conditions, including, e.g., chronic rhinosinusitis, sinusitis, allergic rhinitis and nasal polyps. The composition includes an ionic aqueous solution and algae-derived constituents, such as branched, sulfated polysaccharides having an average molecular weight greater than 4kDa and comprising L-fucose and sulfate ester groups or extracts from brown algae. Also disclosed are methods and pharmaceutical compositions for treating respiratory tract and/or respiratory mucosal-related conditions, including, e.g., chronic rhinosinusitis.
Patent CA-2932315-A1 (CA)
Inventor: SONG RONGJIE
IPC: C22C38/40
Filed: 2013-12-11
Abstract: A cold rolled and annealed martensitic steel sheet is provided. The steel sheet includes by weight percent, 0.30 = C = 0.5%, 0.2 = Mn = 1.5%, 0.5 = Si = 3.0%, 0.02 = Ti = 0.05%, 0.001 = N = 0.008%, 0.0010 = B = 0.0030%, 0.01= Nb = 0.1%, 0.2 = Cr =2.0%, P = 0.02%, S = 0.005%, Al =1%, Mo = 1% and Ni = 0.5%. The remainder of the composition includes iron and unavoidable impurities resulting from melting. The microstructure is 100% martensitic and a prior austenite grain size is lower than 20µm. The steel sheet has a delayed fracture resistance of at least 24 hours during an acid immersion U-bend test. A method, part, structural member and vehicle are also provided.
Patent CA-2932409-A1 (CA)
Inventor: CORNELIUS JACK C
IPC: H01M10/658
Filed: 2016-06-07
Abstract: Thermally-protected heatable chemical cell battery system adapted for providing power to an electronic device comprising a chemical cell battery, control circuitry operatively connected with the battery, a heating element operatively connected with the control circuitry and the battery, the heating element being powered by the battery and located adjacent the battery, the control circuitry providing sufficient power from the battery to the heating element, optionally responsive to a temperature sensor and temperature feedback system, to improve the operating performance of the battery and to control charging, a preferably Aerogel insulating member surrounding the battery and the heating element, contact leads passing through a portion of the insulating member and an optional protective cover adapted for conveying power from the battery to the electronic device.
Patent CA-2932434-A1 (CA)
Inventor: OYA SHUN
IPC: B41J2/175
Filed: 2014-12-09
Abstract: A cartridge (5) is loaded at a carriage (8). The carriage (8) is provided with liquid introduction sections (710m, 710c, 710y) and a guide protrusion section (723). The guide protrusion section (723) extends from between liquid introduction section (710m) and liquid introduction section (710c) toward liquid introduction section (710y). The cartridge (5) is provided with: an ink supply hole (507m) that can connect to liquid introduction section (710m) in a manner so as to supply magenta ink; an ink supply hole (507c) that can connect to liquid introduction section (710c) in a manner so as to supply cyan ink; an ink supply hole (507y) that can connect to liquid introduction section (710y) in a manner so as to supply yellow ink; and a first groove (580). The first groove (580) extends from between ink supply hole (507m) and ink supply hole (507c) toward ink supply hole (507y), and the guide protrusion section (723) can be inserted therein.
Patent CA-2933615-A1 (CA)
Inventor: ELLIOTT ANDREW
IPC: H01L35/28
Filed: 2014-12-19
Abstract: A flow indicator of a breathing apparatus that indicates a flow of a breathing-gas includes a structure within a conduit for delivering the breathable gas, where the structure undergoes a change as a result of a presence of the breathable gas or a movement of the breathable gas past the structure. The flow indicator also includes a gas flow display that is actuated by the change in the structure to visually indicate a presence or flow of the breathable gas, where the display is powered by the change in the structure without any outside power supply.
Patent CA-2935364-A1 (CA)
Inventor: LENZGEIGER ULRICH
IPC: F16H61/40
Filed: 2016-07-07
Abstract: A hydrostatic transmission for a drive train is disclosed, said transmission comprising a first hydraulic machine that can be coupled to a drive machine and comprises an adjustable first displacement volume and is arranged together with at least one second hydraulic machine of the transmission in a hydraulic circuit and said second hydraulic machine can be coupled to an output of the drive train, wherein a control pressure of the transmission at the first hydraulic machine is effective in the direction in which the first displacement volume is increased and a working pressure of the second hydraulic machine that is dependent upon this adjustment is effective in the opposite direction, so that the working pressure can be controlled by way of the control device of the transmission by means of changing the control pressure. A hydrostatic drive train having this transmission is disclosed and a method for controlling the transmission of said drive train is disclosed.
Patent CA-2936587-A1 (CA)
Title: Animal feed covers and systems and methods for their production and use
Inventor: DANENBERG BENJAMIN R
IPC: A01K5/01
Filed: 2016-07-19
Abstract: Covers for sealing and/or bonding with an exposed surface of an animal feed within a container include a flexible film that conforms to the animal feed and a rigid or semi-rigid layer that allows the cover to be handled by an operator during placement of the cover over the animal feed composition while the composition is at elevated temperatures The polymer film may include a heat-activated coating that establishes a bond with the animal feed when the feed is at elevated temperatures or when an external heat source is applied to the cover The heat-activated coating may be flowable at a temperature of at least about 125 °F. Upon placement of the cover over the animal feed, the film conforms to the exposed surface of the feed and the cover forms a seal with the animal feed as flowable coating reaches a flowable temperature.