baber/WOPTO huggingface dataset:
Patent CA-2347060-A1 (CA)
Inventor: ISACCHI ANTONELLA
IPC: C07D417/14
Filed: 1999-10-27
Abstract: L'invention concerne des composés qui sont des dérivés de 2-uréidothiazols de formule (I) dans laquelle R représente un atome d'halogène, un groupe nitro, un groupe amino éventuellement substitué, ou il représente un groupe, également éventuellement substitué, sélectionné parmi i) alkyle C¿1?-C¿6?; ii) cycloalkyle C¿3?-C¿6?; iii) aryle ou arylalkyle comportant de 1 à 6 atomes de carbone dans la chaîne alkyle linéaire ou ramifiée; R¿1? représente un groupe éventuellement substitué sélectionné parmi i) alkyle C¿1?-C¿6? linéaire ou ramifié; ii) un noyau carbocyclique à 3 à 6 chaînons ou hétérocyclique à 5 à 7 chaînons; iii) aryle ou arylcarbonyle; iv) arylalkyle comportant de 1 à 6 atomes de carbone dans la chaîne alkyle; R?2¿ représente hydrogène, un groupe alkyle C¿1?-C¿4?, alcényle C¿2?-C¿4? ou alcynyle linéaires ou ramifiés; ou, avec l'atome d'azote auquel ils sont liés, R¿1? et R¿2? forment un groupe substitué ou non, sélectionné parmi i) un composé hétérocyclique à 5 à 7 chaînons éventuellement benzocondensé ou ponté; ou ii) un composé spiro-hétérocyclique à 9 à 11 chaînons; ou un sel pharmaceutiquement acceptable desdits composés de l'invention. Ces composés et leurs sels servent au traitement des troubles cellulaires prolifératifs liés à une activité de la kinase dépendant de modifications cellulaires.
Patent CA-2347385-A1 (CA)
Title: Transition metal compounds, catalysts for the production of .alpha.-olefins and process therefor
Inventor: WATANABE MASAMI
IPC: C08F10/00
Filed: 2000-08-31
Abstract: Compounds represented by general formula (1); and catalysts for the production of .alpha.-olefins containing the same wherein M is one of Group 8 to 10 transition metals of the periodic table; R1 to R3 and R6 to R15 are each H, halogeno, C1-C20 hydrocarbyl, or a heteroatom-containing group, with at least either of R6 and R10 or at least either of R11 and R15 being H; R4 and R5 are each H or C1-C20 hydrocarbyl, with at least either of them being H or (substituted) aryl; X is a group attached by a covalent or ionic bond; and n is the valence of M.
Patent CA-2347443-A1 (CA)
Title: Retrofit reactor including gas/liquid ejector and monolith catalyst
Inventor: MACHADO REINALDO MARIO
IPC: B01J19/26
Filed: 2001-05-11
Abstract: This invention relates to apparatus suited for gas-liquid reactions such as those employed in the hydrogenation or oxidation of organic compounds. The apparatus comprises the following: a tank having at least one inlet for introduction of liquid, at least one outlet for removal of liquid, and at least one outlet for removal of gas; a pump having an inlet and an outlet; a liquid motive gas ejector having at least one inlet for receiving liquid, at least one inlet for receiving a reactant gas and, at least one outlet for discharging a resulting mixture of said liquid and said reactant gas to a monolith catalytic reactor.  Circulation of liquid is effected from the tank to the ejector, to the monolith catalytic reactor and then back to the tank. Gas is drawn from the tank to the ejector and mixed with the liquid prior to entry to the catalytic reactor.
Patent CA-2348655-A1 (CA)
Title: Process for carbonylation of an allylic butenol or butenyl ester of a carboxylic acid
Inventor: BURKE PATRICK MICHAEL
IPC: C07C51/56
Filed: 1999-11-30
Abstract: A process for the carbonylation of allylic butenol or butenyl ester of a carboxylic acid (e.g., crotyl acetate, 3-acetoxybutene-1 and mixtures thereo f) in an anhydrous carboxylic acid solvent and production of beta-gamma unsaturated carboxylic acid anhydride (e.g., 3-pentenoic acid anhydride) utilizing a rhodium-containing catalyst (e.g., dicarbonylacetylacetonate rhodium (I)) promoted with a metal iodide (e.g., dicarbonylacetylacetonate rhodium (I), or the like). Such a process is particularly useful in the production of beta-gamma unsaturated carboxylic acid anhydride without promoting the back reaction producing butadiene and a carboxylic acid.</SDOA B>
Patent CA-2348681-A1 (CA)
Title: Belt sander with orbitally translated abrasive belt
Inventor: COSTA ALESSANDRO
IPC: B24B21/04
Filed: 2001-05-24
Abstract: A sanding machine for sanding the surfaces of work pieces placed upon a conveyor that transports the work pieces along a first direction towards and beneath a sanding head. The sanding head comprises a sanding belt entrained around an upper tension roller and a lower contact roller. The tension roller and contact roller are provided with a single translational orbital movement by a pair of eccentric shafts operatively connected thereto and rotatably driven by an operatively connected motor. At least one of the upper tension roller and lower contact roller is also driven by an operatively connected motor so as to provide the endless rotation of the sanding belt around the upper tension roller and lower contact roller. In this fashion, the sanding belt is provided with two contemporaneous superimposed movements consisting of rotational movement about the tension roller and contact roller and a single orbital translational movement imparted by the rotating pair of eccentric shafts. The resulting sanding pattern is homogeneous and renders scratches normally created by the endlessly rotating sanding belt substantially unnoticeable. A second embodiment incorporates an arcuate plate in lieu of the upper roller of the sanding head.
Patent CA-2350013-A1 (CA)
Inventor: KAUFHOLD HORST T
IPC: B61G9/04
Filed: 2001-06-08
Abstract: In a slackless railway car connector arrangement, an assembly with a pocket-casting and positive stops connected to a center-sill sidewall is biased by a buff-gear assembly to mechanically ground the connector in the draft direction, but will move longitudinally in the buff direction a predetermined amount against the bias force of the buff-gear assembly until the front plate contact surface contacts the rearward positive stop to limit further buff direction travel of the coupler and pocket casting, which positive stops and pocket casting connections transfer the force load to the plate-reinforced center-sill to cushion the dynamic loading on the coupler assembly.
Patent CA-2350341-A1 (CA)
Inventor: UCHIYAMA MAMORU
IPC: G06F19/00
Filed: 2001-06-12
Abstract: This invention provides a method for predicting pharmacokinetic properties of molecules comprising the steps of: (a) preparing 2D-structures of molecules used as a training set; (b) constructing a 2D-fingerprint by counting the number of structural descriptors that potentially relate to a pharmacokinetic property, either manually or automatically using internally developed macro; wherein said structural descriptors consist of predefined 20 to 80 atoms/fragments or substructures; (c) analyzing the obtained 2D-fingerprint by a statistical analysis method to correlate with the pharmacokinetic property of the molecule to yield a quantitative structure-property relationship (QSPR) model; and (d) calculating the pharmacokinetic property of a trial molecule using the above obtained QSPR model.     A system for this invention is also provided. According to this method and system, it is possible to predict pharmacokinetic properties of molecules prior to synthesis, without labor-intensive and time-consuming experimentation.
Patent CA-2356450-A1 (CA)
Title: An improved process for the preparation of nefazodone hydrochloride
Inventor: CHE DAQING
IPC: C07D249/12
Filed: 2001-09-10
Abstract: A process for the preparation of Nefazodone hydrochloride comprising direct conversion of semicarbazide dihydrochloride 3 into Nefazodone hydrochloride which process involves a reaction of triethyl orthopropionate in the presence of trimethylsilylchloride and hydrochloric acid.
Patent CA-2356816-A1 (CA)
Title: Inhibitors of the egf-receptor tyrosine kinase and their use
Inventor: GHOSH SUTAPA
IPC: A61P35/04
Filed: 2000-03-16
Abstract: Novel compounds and pharmaceutical compositions useful as EGFR tyrosine kinase inhibitors. Methods of the invention include administration of the EGFR TK  inhibitors to treat diseases characterized by enhanced expression of EGF, including cancers, particularly breast cancer. Additionally, a homology model representing the structure of EGFR kinase domain is provided, which model is useful for the rationally design and screening of compounds predicted to bind favorably to EGFR and to inhibit EGFR TK.
Patent CA-2357098-A1 (CA)
Inventor: MCNARY DREW H
IPC: B29C45/44
Filed: 2001-09-06
Abstract: A method for manufacturing a tamper-indicating closure having a plurality of resilient flexible projections bent upwardly and radially inwardly at a predetermined radius of curvature. The first step in the method includes providing a mold assembly comprising a female mold portion for forming the outer surface of the closure and a male mold portion for forming the closure's inner surface and its plurality of projections. The male and female mold portions are arranged for relative movement toward and away from each other between a mold open position and a mold closed position. When in the mold closed position, the male and female mold portions define a mold cavity in which the tamper-indicating closure is molded. The next steps in the method are to move the male and female mold portions into the mold closed position; to provide a mold material into the mold cavity; and, to maintained the mold portions in the mold closed position for a predetermined time period until the tamper-indicating closure is formed with its projections disposed at their predetermined radius of curvature.  Next, the male mold portion is removed from the molded closure, whereby the projections temporarily bend from their predetermined radius of curvature to a second position. The closure includes a plurality of strain relief recesses corresponding to the number of projections, each strain relief recess being located radially outwardly from each projection. Each recess, in combination with the predetermined radius of curvature, acting to limit the extent of deformation of the corresponding projection during removal of the male mold portion so the projection can elastically return to substantially its "as molded" configuration.
Patent CA-2359077-A1 (CA)
Title: Adaptive array communication system and receiver
Inventor: UCHIKI TATSUYA
IPC: H03M13/45
Filed: 2000-07-21
Abstract: An adaptive array communication system comprising an adaptive control sectio n (31) performing weighting and synthesizing for each state of Viterbi decodin g by multiplying signals received from a plurality of antennas by complex weights differing with the state, a decoding section (34)for calculating a metric corresponding to transition to a desired state, and a circuit (33) fo r calculating an error vector for determining complex weight differing with th e state.
Patent CA-2361412-A1 (CA)
Title: Mechanics back ease
Inventor: PICKERING WILLIAM R
IPC: A47C16/00
Filed: 2001-10-19
Abstract: An Apparatus for supporting a mechanic over a motor, in the engine compartment of a motor vehicle. The support has a padded platform with an area on either side of the pad for holding tools, and parts. The padded platform is extendable, as well; the platform is height adjustable.  Adjusting from small cars up to larger trucks. There is an adjustable step, all of which is easily assembled or disassembled, for easy storage. There are small wheels on the bottom of the frame for ease of maneuverability, when moving the "Mechanics Backease", in and out of location.
Patent CA-2361691-A1 (CA)
Title: Speaker apparatus
Inventor: YOSHII HIROYUKI
IPC: H04R9/02
Filed: 2001-11-09
Abstract: A weight is attached to the rear side of a magnetic circuit of a speaker unit. The tip of a boss that projects to the front side from the weight is joined to the rear side of a center pole of the magnetic circuit with a bolt. Even if reactive force that is generated when an electrical signal is converted into mechanical vibration by the magnetic circuit and a voice coil and sound waves are emitted from a vibration plate is transmitted to the magnetic circuit, the vibration of the magnetic circuit is suppressed by the weight. In this manner, sound quality with a good transient characteristic can be obtained.
Patent CA-2362512-A1 (CA)
Title: Boite distributrice de lingettes nettoyantes
Inventor: FRANZ DIETER
IPC: B65D83/08
Filed: 2000-03-01
Abstract: La présente invention concerne une boîte distributrice (100) de lingettes nettoyantes (48) destinées au nettoyage d'installations sanitaires ou des surfaces d'une salle de bain ou de WC. Cette boîte comprend un corps (10) accueillant une pile de lingettes (48). Ce corps (10), qui définit un haut (12) et un bas (14), est configuré pour s'ouvrir par le haut (12). Il se referme par un couvercle amovible (16). Le corps (10) présente également, configuré dans le couvercle (16), un orifice (30) permettant de prélever des lingettes (48). Ces boîtes, qui sont peu commodes à utiliser, nécessitent généralement les deux mains pour prélever les lingettes, et toute l'attention de l'utilisateur. L'invention propose donc pour le corps (10) une configuration cuboïde définissant deux petits côtés opposés (20) et deux grands côtés opposés (22) d'une hauteur définie, la largeur du grand côté (20) étant supérieure à la largeur d'un petit côté (22), et la hauteur supérieure à la largeur du grand côté (20). En outre, un socle (18) présente des dimensions de contour supérieures à celle du corps (10), le bas (14) du corps (10) et le socle (18) étant configurés de façon que le socle (18) puisse se monter et se démonter du bas.
Patent CA-2363267-A1 (CA)
Title: Aqueous coating compositions with phosphonic acid based compounds
Inventor: HUYBRECHTS JOSEF
IPC: C08G59/40
Filed: 2001-11-15
Abstract: The invention is directed to gassing stabilized aqueous coating compositions comprising A) a metallic pigment and at least one reaction product of (a) 5 to 95 weight percent of a at least one phosphonic acid derivative selected form compound I and II   (see formula I) wherein R1 is H or O=P(OH)2 ; R2 and R3 are independently H, OH or an aliphatic, cycloaliphatic and aromatic substituent having 1 to 25 carbon atoms and optionally up to 10 heteroatoms of at least one of oxygen and phosphorus; and R' is an aliphatic, cycloaliphatic and aromatic substituent having 1 to 25 carbon atoms and optionally up to 10 heteroatoms of at least one of oxygen and phosphorus; (b) 5 to 95 weight percent of a at least one compound having at least two epoxy groups and a number average molecular weight Mn of 300 to 5000 g/mol; and (c) 0 to 90 weight percent of a compound having one epoxy-functional group, wherein the proportions by weight of components (a), (b) and (c) total 100 weight percent.   B) at least one metallic pigment.
Patent CA-2366410-A1 (CA)
Title: Method for emptying a blood circuit of an apparatus for the extracorporeal treatment of blood
Inventor: PEDRAZZI RENATO
IPC: A61M1/36
Filed: 2001-01-12
Abstract: A method for emptying a blood circuit of an apparatus for the extracorporeal treatment of blood after interrupting a treatment session, the apparatus comprising: a blood treatment device (4) having a first and a second compartment (5, 6) separated from one another by a semi permeable membrane (7), an arterial pipe (8) connected to an inlet of the first compartment (5), a venous pipe (9) connected to an outlet of the first compartment (5) and a second end, a used liquid circuit (6, 21) having a drain pipe (21) connected to an outlet of the second compartment (6), whereby the method comprises the steps of: closing on itself a blood circuit (2) comprising the arterial pipe (8), the first compartment (5) of the blood treatment apparatus (4) and the venous pipe (9) in order to form a closed loop circuit, after the arterial and venous pipes (8, 9) have been disconnected from the vascular system of the patient, the blood circuit containing a liquid, transferring the liquid contained in the closed loop circuit into the used liquid circuit (6, 21), and draining the liquid transferred into the used liquid circuit (6, 21) using the drain pipe (21).
Patent CA-2366676-A1 (CA)
Inventor: HAMANN DAVID L
IPC: A61B10/00
Filed: 2000-03-21
Abstract: L'invention concerne un dispositif automatisé de biopsie à l'aiguille (100, 192, 250) pour l'extraction de tissus corporels, notamment dans des cas présumés d'un cancer du sein. Le dispositif peut cependant s'utiliser dans d'autres parties du corps accessibles à la biopsie à l'aiguille. Le dispositif (100, 192, 250) entraîne une aiguille fine (122) qui lui est fixée à imprimer un mouvement de va-et-vient et/ou de rotation au moyen d'un ensemble came (154, 324, 331, 338, 350, 362, 376), entraînant simultanément la pénétration des tissus dans l'aiguille (122). La profondeur et le nombre des poussées peuvent être préprogrammés, et la force derrière chaque poussée est constante. On peut éventuellement utiliser l'aspiration. Les tissus extraits sont ensuite projetés sur des lames de verre pour une analyse au microscope. Ce dispositif (100, 192, 250) et cette méthode apportent une amélioration majeure par rapport à la méthode de biopsie à l'aiguille existante qui est réalisée manuellement et approximativement. L'inconvénient principal de la méthode manuelle actuellement utilisée est une extraction tissulaire insuffisante. Le dispositif de l'invention (100, 192, 250) corrige ce phénomène, permettant un diagnostic précis des échantillons tissulaires adéquats obtenus. Il n'existe, à l'heure actuelle, aucun dispositif semblable à utilisation clinique.
Patent CA-2367588-A1 (CA)
Title: Panty liner with sensor for predicting the start of menstruation
Inventor: GUERRESCHI LISA
IPC: G01N33/50
Filed: 2000-04-26
Abstract: The present invention relates to use of a pH sensor, blood sensor, progesterone and/or estrogen hormone sensor or combinations thereof in the manufacture of a sanitary napkin, panty liner for conventional use by a woma n. The use of the sensor is for the purpose of providing a visual advance indication of at least 3 hours until the start of menstruation.
Patent CA-2367966-A1 (CA)
Title: Texture description method and texture-based retrieval method in frequency domain
Inventor: YOU KI WON
IPC: G06F17/30
Filed: 2000-07-07
Abstract: The present invention relates to a texture description method in frequency domains and a texture-based retrieval method using the same, in which image signals are converted into those in a frequency domain of Polar coordinate system. The texture description method in the frequency domain comprises: a first step of generating a frequency layout by partitioning the frequency domain into a set of feature channels; a second step of extracting the texture feature values of the image from the respective feature channels; and a third step of constituting a texture descriptor of the image in a vector form using the texture feature values extracted from the respective feature channels of the frequency layout. According to the present invention, in a texture-based retrieval described in the frequency domain, a retrieval method capable of satisfying respective or all the retrieval conditions such as scale-, rotation- and intensity-invariant retrieval of relevant texture images is provided. Also, a retrieval method of computing the rough scheme of texture to provide a browsing functionality in retrieving is provided.
Patent CA-2369007-A1 (CA)
Title: Powdered human milk fortifier
Inventor: O'CONNOR DEBORAH L
IPC: A23L33/15
Filed: 2000-04-07
Abstract: The invention relates to a powdered human milk fortifier comprising a protein component typically present in an amount of from about 24 wt/wt% to about 55 wt/wt% of the fortifier powder, and a fat component typically present in an amount of from about 1 wt/wt% to about 30 wt/wt% of the fortifier powder and a carbohydrate component present in a quantity of from about 15 wt/wt% to about 75 wt/wt% of the fortifier powder. Preferably, the powdered human milk fortifier is provided in a unit dose container which holds from about 0.5 gm to about 10 gm of powder. The instant invention also relates to a method of providing nutrition to preterm infants by adding a fortifier powder to human milk and administering the fortified human milk to a premature infant. The invention further provides a method of promoting growth of a premature infant by administering fortified human milk to a premature infant.
Patent CA-2373476-A1 (CA)
Inventor: NEHL WOLFGANG
IPC: F16B13/06
Filed: 2001-01-18
Abstract: The invention relates to a plug (10) for fastening to hollow or panel-type building materials and to solid building materials. The invention proposes providing the plug (10) with expansion limbs (18) that extend longitudinally and that are connected to one another by thin skins (22) having a corrugation in the peripheral direction. That has the advantage of good screw guidance and a torsionally rigid construction of the plug (10); especially when fastening to hollow and panel-type building materials, undesirable backwards rotation of the plug tip (16) is avoided when screwing in an expansion screw by hand. Angled slits (32) in the plug tip (16) bring about good adaptation to screws having different diameters and different pitches of thread.
Patent CA-2377341-A1 (CA)
Inventor: RUTLEDGE MELVIN CLARENCE
IPC: A61P31/20
Filed: 2000-06-15
Abstract: This invention provides for a method of treating a chemokine mediated disease, wherein the chemokine is one which binds to an IL-8 .alpha. or .beta. receptor and which method comprises administering an effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof. In particular the chemokine is IL-8.
Patent CA-2383668-A1 (CA)
Title: Rotary steerable drilling tool
Inventor: KOTSONIS SPYRO
IPC: E21B7/08
Filed: 2002-04-26
Abstract: The invention refers to a rotary steerable drilling tool having a tool collar and a bit shaft. The bit shaft is supported within the tool collar for pivotal movement about a fixed position along the bit shaft. Moreover, the rotary steerable drilling tool includes a variable bit shaft angulating mechanism, located within the interior of the tool collar. The variable bit shaft angulating mechanism includes a motor, an offset mandrel, and a variable offset coupling. The motor is attached to the upper end of the offset mandrel and adapted to rotate the offset mandrel. The upper end of the variable offset coupling is uncoupleably attached to an offset location of the lower end of the offset mandrel, and the upper end of the bit shaft is rotatably coupled to the variable offset coupling. The rotary steerable drilling tool also includes a torque transmitting coupling adapted to transmit torque from the tool collar to the bit shaft at the fixed position along the bit shaft. Finally, a seal system is adapted to seal between the lower end of the tool collar and the bit shaft.
Patent CA-2384003-A1 (CA)
Inventor: BELLEY PASCAL
IPC: B44D3/14
Filed: 2002-05-14
Abstract: A movable device receiving a paint pan for a painter or the like, including a frame member having the side walls provided with spaced aligned holes formed therein, allowing to lock the side walls of the frame member according to the desired length and/or width, which are extended and/or shortened by adjustable means to permit use of the device with any size of paint pan, and which are connected by the use of bolts and nuts, or other conventional fastenings means. A bar is connected onto the locking means of front or back casters of the self-steering swivel type, allowing to lock the both front or back casters in same time during the painting works.
Patent CA-2386871-A1 (CA)
Inventor: DAVIS SANDRA S
IPC: A61Q5/00
Filed: 2000-10-06
Abstract: The invention provides personal care compositions which include polymers of isoprene, butadiene and/or styrene, particularly conjugated dienes which may  be subject to some degree of hydrogenation. A copolymer of two different conjugated dienes is preferred. The polymers may be selectively hydrogenated  to produce polymers which have highly controlled amounts of unsaturation, thereby improving film forming properties.