baber/WOPTO huggingface dataset:
Patent IL-148704-A0 (IL)
Title: Antibiotic(s)-polymer combination
IPC: A61K47/32
Filed: 2002-03-14
Abstract: Incorporation of an aminoglycoside, lincosamide, tetracycline, quinolone or  beta -lactam antibiotic in a homogeneous mixture of a hydrophobic polymethacrylate, polyacrylate and/or poly(methacrylate-co-acrylate) polymer and a hydrophilic polyether polymer provides continuous release of the antibiotic. An antibiotic-polymer composite comprises a suspension of one or more aminoglycoside, lincosamide, tetracycline, quinolone or  beta -lactam antibiotics and optionally one or more organic additives in a homogeneous polymer mixture of one or more hydrophobic polymethacrylate, polyacrylate and/or poly(methacrylate-co-acrylate) polymers and one or more hydrophilic polyether polymers. The aminoglycoside, lincosamide and tetracycline antibiotics have poor water-solubility or may be readily soluble in water, the quinolone antibiotics have a poor solubility in water and the  beta -lactam antibiotics may be readily soluble in water.
Patent IL-157342-A0 (IL)
Title: Process for producing quinoline carboxyaldehyde derivative and intermediate thereof
IPC: C07D215/14
Filed: 2002-02-14
Abstract: 2-Cyclopropyl-4-(4'-fluorophenyl)quinoline-3-carboxyaldehyde useful as a material for pharmaceutical products, can be obtained by reacting 3-cyclopropyl-3-oxopropanenitrile with 2-amino-4'-fluorobenzophenone to obtain 2-cyclopropyl-4-(4'-fluorophenyl)quinoline-3-carbonitrile, and reducing it.
Patent IL-172784-A0 (IL)
Title: A seed tape including successively arranged germinating units
IPC: A01C1/04
Filed: 2005-12-22
Abstract: A seed tape includes successively arranged germinating units including at least one carrier strip and at least one auxiliary layer of biodegradable, flexible, non-woven or film-like material arranged on the carrier strip, whereby the auxiliary layer is locally interrupted a short distance along the seed tape, and whereby each germinating unit includes a mixture of granulated carrier, at least one granulated additive and an adjuvant in addition to one or more seeds. The mixture plus the seed(s) are kept together to form at least one core portion including an incision, in the germinating unit, and whereby the seed tape can be cut into separate germinating units prior to irrigation and/or bedding out, the core portion made of the mixture including locally adhered fibers of one or more thermoplastic materials which form a coherent, open network for keeping the granules of the mixture together. The fibers of one or more thermoplastic materials which form the network are bicomponent fibers, and the seed or seeds is/are placed in the incision in the core portion, the incision being of a depth of 25 to 50% of a thickness of the core portion. An outer component of each bicomponent fiber is made of polyactide (derived from lactic acid) (PLA) having a relatively low melting point, whereas an inner component of the fiber is made of polyactide (derived from lactic acid) (PLA) having a relatively high melting point.
Patent IL-173078-A0 (IL)
Title: Multiparticle pharmaceutical dosage form containing a mucoadhesively formulated peptide or protein active substances method for producing said pharmaceutical dosage form
IPC: A61K9/26
Filed: 2006-01-11
Abstract: The invention relates to an oral, multiparticle pharmaceutical dosage form containing pellets, the size of which ranges from 50 to 2500 μm and which essentially consist of: a) an inner matrix layer containing an active substance which is a peptide or a protein, including the derivatives or conjugates thereof, and which is embedded in a matrix consisting of a polymer with mucoadhesive effect, and b) an outer film coating essentially consisting of an anionic polymer or copolymer, which can be optionally formulated with pharmaceutically conventional adjuvants, more particularly softening agents.
Patent IL-179415-A0 (IL)
Title: Method and apparatus for detecting zero rate frames in a communications system
IPC: H04B7/005
Filed: 2006-11-20
Abstract: Techniques for detecting zero rate frames in a received data transmission. A modulated signal is received and demodulated in accordance with a particular demodulation format to generate demodulated symbols. The demodulated symbols are partitioned into a number of received frames. For each received frame, a quality metric is computed and compared against a threshold value. The threshold value is selected based, in part, on the quality metrics of received frames. Based on the comparison result, the received frame is indicated as being either transmitted and received in error (i.e., erased or bad) or not transmitted at all (i.e., zero rate or empty). The quality metric can relate to an energy of a received frame, a distance between a received frame and a codeword corresponding to the received frame, or other metrics. The threshold value can be selected based on the quality metrics computed for decoded frames or received frames identified as good, and can be dynamically adjusted based on current information available at the receiver. The method is advantageously used in a CDMA communications system.
Patent AP-2001002159-A0 (AP)
Title: Inorganic cementitous material.
Inventor: MCNAULTY WILLIAM J JR
IPC: C04B7/345
Filed: 1999-12-07
Abstract: A method of producing a new type of cement, hereafter called Conch-krete. Conch-krete is created by adding sodium carbonate (also known as soda ash, natron, etc.)And one or more minerals from the calcium carbonate group (including aragonite, limestone, calcite, marble, dolomite, etc.) and the addition of water to the mix that will harden into a cement-like material. The combination of sodium carbonate and calcium carbonate can be either layered or in a mixed state. An exothermic reaction starts after the addition of water. The composition of Conch-krete can vary between 20% sodium carbonate and 80% calcium carbonate to 80% sodium carbonate and 20% calcium carbonate. Conch-krete can be used in a variety of applications not inclusive of forming bricks, interior architecture, table or counter tops, ornaments, repairing damaged cement products, casting and other applications not mentioned above.
Patent IE-910751-A1 (IE)
Title: Esterase from serratia and process for preparing the same
Inventor: SHIBATANI TAKEJI
IPC: C12N9/18
Filed: 1991-03-06
Abstract: A novel esterase which is derived from Serratia marcescens is disclosed. Said esterase has the following physico-chemical properties and enzymatic charactaristics: (1) Activity; it (i.e., said esterase) hydrolyzes an ester bond of organic carboxylates, (2) Substrate specificity; it acts on alkyl esters of organic carboxylic acids, triglycerides or thiol esters, (3) Optimum pH; its optimum pH is 7.5 - 9.0 when the hydrolysis is carried out by using olive oil as the substrate, (4) pH stability; it is stable at pH 5.0 - 9.0 when it is stored at 30  DEG C for one hour, (5) Optimum temperature; its optimum temperature is 40 - 50 DEG C when the hydrolysis is carried out by using olive oil as the substrate, (6) Heat stability; it is stable at a temperature of not higher than 50 DEG C when it is stored at pH 8.0 for 30 minutes, (7) Molecular weight; 62, 000 +/- 2,000 (SDS-polyacrylamide gel electrophoresis), (8) Isoelectric point; 4.6 +/- 0.1, (9) Effect of metal ions; it is activated in the presence of 1 mM calcium ion, and inhibited in the presence of 1 mM cobalt ion, nickel ion, iron ion or ethylenediaminetetraacetic acid. Said esterase can widely be applied for organic synthetic reactions.
Patent MA-20461-A1 (MA)
IPC: C07D215/56
Filed: 1985-06-24
Abstract: 1. Derivatives of isoxazoloquinolinone characterized in that they answer to the general formula l  see diagramm : EP0168309,P8,F1  in which R represents a hydrogen, fluorine, chlorine or bromine atom, a linear alkyl radical containing from 1 to 5 carbon atoms, or branched alkyl radical containing from 3 to 5 carbon atoms, an alkoxy radical containing from 1 to 5 carbon atoms, a nitro or trifluoromethyl radical and R1  represents a phenyl radical possibly substituted by a linear alkyl radical containing from 1 to 5 carbon atoms, or a branched alkyl radical containing from 3 to 5 carbon atoms, by an alkoxy radical containing from 1 to 5 carbon atoms, or by a halogen atom.
Patent MA-25001-A1 (MA)
Title: Shampooings perfectionnes avec stabilisants
Inventor: CHARLES REICH
IPC: A61K8/92
Filed: 1999-10-05
Abstract: CETTE INVENTION SE RAPPORTE à DES COMPOSITIONS DE SHAMPOOINGS STABILISÉS PERFECTIONNÉS CONTENANT DES MATIèRES DE SILOXYSILICATE QU'EN LANGAGE COURANT ON DÉSIGNE SOUS LE NOM DE RÉSINES MQ,  DANS LESQUELLES LES STABILISANTS SONT SÉLECTIONNÉS à PARTTIR DE ( I )  ALCOOLS GRAS EN CHAiNE LONGUE AYANT PLUS DE 14 CARBONNES;  ( II )  COPOLYMèRE MÉTHACRYLATE D'ACYLATES/STÉARETH-20;  COPOLYMèRE D'ACRYLATES;  POLYMèRE CROISÉ ALKYLACRYLATE D'ACRYLATES/C10-30. ET ( III ) ACIDES PHTALAMIQUES N,N-DISUBSTITUÉS ET LEUR SELS D'AMMONIUM.
Patent MA-27713-A1 (MA)
Title: Composes aminoheteroaryliques servant d'inhibiteurs de proteine-kinases
Inventor: CUI JINGJONG JEAN
IPC: C07D419/00
Filed: 2005-08-26
Abstract: DEPOSANT Société dite : SUGEN, INC. REVENDICATION DE PRIORITES US 26 Février 2003 60/449,588 US 29 Janvier 2004 60/540,229 Composés aminohétéroaryliques servant d'inhibiteurs de protéine-kinases Des aminopyridines et aminopyrazines de formule (I), des compositions comprenant ces composés et des méthodes d'utilisation sont proposés. Les composés préférés de formule (I) ont une activité d'inhibiteurs de protéine-kinases, y compris comme inhibiteurs de c-MET.
Patent MA-38349-A1 (MA)
Title: Œstra-1,3,5(10),16-tétraéno-3-carboxamide pour inhiber la 17-bêta-hydroxystéroïde déshydrogénase (akr1c3)
Inventor: BOTHE ULRICH
IPC: C07J43/00
Filed: 2014-02-18
Abstract: L'invention concerne des inhibiteurs de l'akr1c3 suivant la formule (i) et des procédés pour les préparer, leur utilisation dans le traitement et/ou la prévention de maladies ainsi que leur utilisation pour fabriquer des médicaments destinés au traitement et/ou à la prévention de maladies, en particulier des troubles hémorragiques et de l'endométriose.
Patent MA-47631-A1 (MA)
Title: Dispositif de pulvérisation multipoint pour additif liquide de nutrition végétale pour engrais
Inventor: CAO SUFEN
IPC: C05G3/00
Filed: 2017-09-19
Abstract: La présente invention concerne un dispositif de pulvérisation multipoint pour un additif liquide de nutrition végétale pour engrais, comprenant un tuyau en tissu et une pluralité de buses coniques et étant caractérisé en ce que : le tuyau en tissu est installé à l'intérieur d'un rouleau de revêtement, et la pluralité de buses coniques sont disposées de manière régulière sur le tuyau en tissu, une extrémité du tuyau en tissu étant reliée à un tuyau pour transporter un additif liquide de nutrition végétale, tandis que l'autre extrémité est bloquée à l'aide d'un bouchon. Par l'utilisation du dispositif de la présente invention, l'additif liquide de nutrition végétale à l'intérieur du rouleau de revêtement est pulvérisé uniformément et est pulvérisé sur une surface de lit de matière qui est formée par un engrais à l'intérieur du rouleau de revêtement de telle sorte qu'une surface d'un engrais granulaire ou d'un engrais en feuille est revêtue d'une couche de l'additif liquide de nutrition végétale. La présente invention possède une structure simple, est facile à fabriquer et présente de faibles coûts. Les avantages de l'invention sont les suivants : 1. La pulvérisation multipoint est uniforme; 2. La structure du dispositif est simple.
Patent UY-28287-A1 (UY)
Title: Combinaciones para el tratamiento de enfermedades que impican proliferación, migración o apoptosis celulares de células de mieloma, o angiogénesis
Inventor: SOLCA FLAVIO
IPC: A61K31/56
Filed: 2004-04-23
Abstract: La presente invención se refiere a una combinación farmacéutica para el tratamiento de enfermedades que impliquen proliferación, migración o apoptosis celulares de células de mieloma o angiogénesis. La invención también se refiere a un método para el tratamiento de dicha enfermedades, que comprende la co-administración de cantidades efectivas de compuestos activos especificos y/o el co-tratamiento con terapia de radiación, en una relación que proporciona un efecto aditivo o sinérgico, y al uso combinado de estos compuestos especificos y/o radioterapia para fabricación de las preparaciones de combinación farmacéuticas correspondientes.
Patent UY-28668-A1 (UY)
Title: Hormonas de administración transdérmica que no necesitan potenciadores de penetración
Inventor: DITTGEN MICHAEL
Filed: 2004-12-10
Abstract: Un parche que comprende una capa de droga con un bajo contenido de hormonas, como por ejemplo gestodeno, y opcionalmente un estrógeno (por ejemplo etinilestradiol). Al aplicar el parche a una mujer, se consiguen niveles en plasma de al menos 1.0ng/ml de gestodeno en condiciones de estado estacionario sin necesidad de indorporar potenciadores de penetración ni mejoradores de permeación en la capa que contiene droga. También son satisfactorios los niveles en plasma de las hormonas que se consiguen durante todo un período de al menos 1 semana, haciendo que el parche se pueda aplicar para utilizarlo en anticoncepción femenina con el concepto de aplicar el parche una vez a la semana.
Patent UY-31020-A1 (UY)
Title: 2-amino-7,8-dihidro-6h-pirido[4,3-d]pirimidina-5-onas
Inventor: RENHOWE PAUL A
IPC: A61K31/519
Filed: 2008-04-11
Abstract: Los compuestos revelados son 2-amino-7,8-dihidro-6H-pirido[4,3-d]pirimidina-5-uno, sus estereoisomeros, tautomeros, sales aceptables farmacéuticamente, y pro-medicamentos de lo mismo; las composiciones que incluyen un portador farmacéuticamente aceptable y uno o más de los compuestos 2-amino-7,8-dihidro-6H-pirido[4,3-d]pirimidina-5-uno, ya sea solos o en combinacion con por lo menos un agente terapéutico adicional. Se revelan los métodos de uso de los compuestos 2-amino-7,8dihidro-6H-pirido [4,3-d]pirimidina-5-uno, ya sea o en combinacion con por lo menos un agente terapéutico adicional, en la profilaxis o tratamiento de las enfermedades del sistema nervioso central, cardiovasculares, autoinmune, virales, y de proliferacion celular.
Patent ES-182530-A1 (ES)
Title: DISPOSITIVO DE MANDO HIDRáULICO O NEUMáTICO DE MáQUINAS PARA LA FABRICACIoN DE AMPOLLAS DE VIDRIO
Filed: 1948-02-20
Abstract: Dispositivo para el mando de los órganos móviles de las máquinas para la fabricación de ampollas de vidrio, caracterizado porque los distintos órganos que han de realizar desplazamientos están accionados por motores hidráulicos o neumáticos.
Patent ES-184316-A1 (ES)
Title: UN SISTEMA DE SENALIZACIoN PARA TELEFONiA AUTOMáTICA
Filed: 1948-06-26
Abstract: En un sistema de señalización el método para efectuar la señalización en el que una señal está caracterizada por dos impulsos separados por un intervalo de tiempo dado.
Patent ES-191512-A1 (ES)
Title: Perfeccionamientos en filetas de hilatura.
Filed: 1950-02-02
Abstract: Perfeccionamientos en filetas de hilatura caracterizados porque el bastidor de las mismas está provisto cerca de cada espiga de un dispositivo de tensión y la parte anterior de la fileta contiene un número igual de dispositivos tensores montados de modo tal que cada hilo al salir de su bobina y dirigirse al dispositivo colector se mantiene prácticamente horizontal entre los dos dispositivos de tensión aunque el dispositivo colector esté fijo o haya girado ligeramente hacia atrás.
Patent ES-195270-A1 (ES)
Title: Procedimiento de fabricacion de tortas
Filed: 1950-11-07
Abstract: Un procedimietno de fabricación de tortas caracterizado porque en un recipiente adecuado se vierten 1.000 grmas de almendras peladas y trituradas muy finamente; 300 grms de azúcar fina blanca; 150 grmas de harina de trigo; 25 grms de coco y la cantidad de agua suficiente para obtener una pasta o masa homogenea verificado lo cual se traslada la masa así obtenida a unos tableros preparados al efecto en donde es extendida para darle el grueso deseado procediéndose después al trozeado correspondiente con unos moldes de forma elíptica cuyos ejes mayores tienen 5 y 10 cm respectivamente.
Patent ES-259306-A1 (ES)
Title: Method for stereospecific polymerization of acrylo monomers in the presence of a metal amide
IPC: C08F20/12
Filed: 1960-06-28
Abstract: Esters and nitriles of acrylic and methacrylic acids are polymerized in the presence of catalysts of the formulae <FORM:0912404/IV(a)/1> where R1 and R2 are alkyl, cycloalkyl, aryl alkaryl or aralkyl groups, either the same or different from one another, or forming together with the nitrogen atom a heterocyclic ring, R3 and R4 are alkyl, aralkyl or aryl groups, MeI is an alkali metal, MeII is a metal of Group I, II or III of the Periodic Table according to Mendel<\>aeeff, X is hydrogen or a halogen, pis 0 or 1, n is 0 or a whole number, m+n is equal to the sum of the valencies of MeI and MeII, and g is 0 or 1. Representative catalysts are those of the formulae: <FORM:0912404/IV(a)/2> O(C2H5)2 LiAl[N(C2H5)2]3H (Al[N(CH3)2])2 Al[N(C6H5)2]2Cl Be[N(C6H5)2]2 and LiNC12H8 (carbazyl lithium). Acrylic monomers specified are isopropyl and tert-butyl acrylates, methyl methacrylate and acrylonitrile. Polymerization is carried out in an inert diluent, e.g. toluene, and gives rise to polymers which exhibit stereoregularity and, in the case of acrylonitrile and esters containing branched alkyl groups, crystallinity. The crystalline polymers may be formed into filaments or films which may be subjected to various after-treatments, e.g. cross-linking by transesterification with polyfunctional alcohols, partial saponification to improve the dyeability and render the polymers hydrophilic, complete saponification to produce crystalline polyacrylic acids, and reaction with polyamines to render the polymers solvent resistant. Reference has been directed by the Comptroller to Specification 884,733.ALSO:Compounds are produced which have the formula: <FORM:0912404/IV (b)/1> where R1 and R2 are alkyl, cycloalkyl, aryl, alkaryl or aralkyl groups, either the same or different from one another or forming together with the nitrogen atom a heterocyclic ring, R3 and R4 are alkyl, aryl or aralkyl groups, MeI is an alkali metal, MeII is a metal of Group I, II or III of the Periodic Table according to Mendeleef, X is hydrogen or halogen, p is 0 or 1, n is 0 or a whole number, m + n is equal to the sum of the valencies of MeI and MeII, and g is 0 or 1. The following preparations of compounds of the above type are described: (A) lithium aluminium hydride is reacted with an ether solution of diphenylamine to produce the compound <FORM:0912404/IV (b)/2> , (B) lithium aluminium hydride is reacted with diethylamine to produce the compound LiAl[N(C2H5)2]3H, (C) diethyl beryllium is reacted with diphenylamine to produce the compound Be[N(C6H5)2]2, (D) aluminium triisopropyl is reacted with dimethylamine to produce the compound (Al[N(CH3)2]3)2, and (E) aluminium diethyl chloride is reacted with diphenylamine to produce the compound Al[N(C6H5)2]2Cl. Reference has been directed by the Comptroller to Specification 884,733.
Patent ES-340760-A1 (ES)
Title: Cedrol ethers
IPC: C11B9/00
Filed: 1967-05-19
Abstract: Novel cedryl ethers of formula <FORM:1115540/C2/1> where R is C1- 4 alkyl, allyl or methallyl, are prepared by reacting an alkali metal derivative of cedrol, prepared from cedrol and sodium hydride or sodamide, with C1- 4 alkyl halide, a dialkyl sulphate, a C1- 4 alkyl ester of an aryl sulphonic acid, allyl halide or methallyl halide. Examples describe the preparation of cedryl methyl ether, cedryl allyl ether, and cedryl ethyl ether. An example also describes the hydrogenation of cedryl allyl ether over palladium carbon catalyst to give cedryl propyl ether. These compounds are used as active ingredients in perfume compositions.ALSO:Perfume compositions contain novel cedryl thers of formula <FORM:1115540/A5-A6/1> where R is C1-4 alkyl, allyl or methallyl, in addition to other substances. An example describes a formula for a perfume of Bergamot Oil, Orange Oil, Bitter Orange Oil, Lemon Oil, Mandarin Oil, Lime Oil, Ocimene, ortho tertiary butyl cyclohexyl acetone and cedryl methyl ether.
Patent ES-344211-A1 (ES)
Title: Heat Exchanger
IPC: F24H1/43
Filed: 1967-08-18
Abstract: In a boiler comprising concentric walls 5, 6 formed by coiled tubes and defining annular passages through which the flue gases flow from the combustion space 10, the boiler is formed of separate sections 2 joined together, each section comprising a portion of the outer wall and a section of the walls 5, 6. The tubes in the walls 5, 6 may be connected in series, the outer wall portion in each section being connected to the inner wall portion and the outlet pipe of the tubes in each section connected to the inlet pipe of the tubes in the adjacent section. Alternatively the tubes in each section may be connected in parallel, the inlet to the tubes in each section being connected to a common inlet manifold and the outlet to a common outlet manifold. The ends of the combustion space are closed by ceramic walls 11, 12, with a burner mounted at 13, and superheater tubes 8 may be mounted in one of the annular flues. Each section 2 may be provided with support members 18.
Patent ES-349034-A1 (ES)
Title: 2-cycloalkylamino-oxazolines
IPC: C07D263/28
Filed: 1968-01-09
Abstract: Novel compounds of the general formula or their tautomers of formula wherein R is an alkyl radical with 1 to 3 carbon atoms, R 1 is an alkyl radical with 1 to 5 carbon atoms, n is an integer from 3 to 5, m is an integer from 0 to 2, and p = m or m+2, and wherein the cycloalkyl moiety may contain a double bond, with the proviso that such double bond must not be in the alpha, beta-position, are prepared either by reacting a compound of formula with ethanolamine or by cyclization of a reactive ester of a compound of the formula optionally followed by formation of the free base by treatment of the salt with ammonia or conversion of the base to another acid addition salt. Halides of the alcohols of the last general formula above are prepared by reaction of a beta-haloethyl-isocyanate with a cycloalkylamine of the formula The amines of the last general formula above may be prepared either by reduction of the corresponding oxime or in the case of the cyclohexyl compounds by the reduction of the corresponding analine. All of these amines are characterized as their benzoyl derivatives. The novel compounds are stated to have various pharmaceutical activities.
Patent ES-352533-A1 (ES)
Title: Preparation of aromatic isocyanates
IPC: C07C/
Filed: 1968-04-08
Abstract: Catalysts for the preparation of aromatic isocyanates comprise combinations of palladium dichloride and/or rhodium trichloride with vanadium pentoxide or molybdenum dioxide. Platinum tetrachloride or cupric bromide may be included. The catalyst may be deposited on alumina, silica carbon, barium sulphate, calcium carbonate, asbestos bentonite, diatomaceous earth or Fullers earth as a carrier. Certain organic and inorganic acid halides enhance the activity of the catalyst. Phosphorus and vanadium oxychlorides are particularly specified.