baber/WOPTO huggingface dataset:
Patent EP-3997117-A1 (EP)
Title: Compositions and methods for enhancing cell culture
Inventor: MANSOUR SARYA
IPC: C07K14/775
Filed: 2020-07-06
Abstract: Provided herein are improvements in cell culture methods and compositions related thereto. In partial particular, provided herein are compositions and methods, and kits increasing the cellular division times and viability. Also provided herein are compositions and method for performing electroporation where high levels of electroporation efficiency are achieved and where deleterious effect of electroporation on cells are decreased.
Patent EP-3924335-A1 (EP)
Inventor: GOMER RICHARD H
IPC: C07D213/81
Filed: 2020-02-10
Abstract: The present disclosure relates to methods of preventing or inhibiting fibrosis using small molecule sialidase inhibitors. The present disclosure also relates to methods treating obesity, liver inflammation, steatosis, and cancer. These methods can involve administering the compounds to a patent at risk of developing fibrosis inflammation, obesity, steatosis, or cancer, in a manner that inhibits NEU3.
Patent EP-3924533-A1 (EP)
Inventor: DETWEILER ZACHARY M
IPC: C21D1/26
Filed: 2020-02-14
Abstract: La présente invention concerne des systèmes et des procédés qui permettent de déposer une couche métallique de manière adjacente à un substrat ou sur celui-ci. Un substrat peut être utilisé. Le substrat peut être mis en contact avec une bouillie comprenant un oxyde métallique, un agent métallique réducteur et un activateur de transport de métal, pour fournir une couche contenant du métal adjacente au substrat. Le substrat et la ou les couches contenant du métal peuvent être recuits de telle sorte que l'oxyde métallique et l'activateur de transport de métal subissent une réaction de réduction métallothermique pour produire la ou les couches contenant du métal et de l'eau. L'eau peut être réduite par l'agent métallique réducteur.
Patent EP-4018692-A1 (EP)
Title: Path selection or path switching and charging for proximity service communication
Inventor: LI HONGKUN
IPC: H04W36/24
Filed: 2020-08-03
Abstract: A 5G network may support path switch mechanisms from a direct path to an indirect path to the network, and vice versa. Methods and systems are disclosed for performing the path switching process.
Patent EP-4025830-A1 (EP)
Inventor: MASON STEPHEN
IPC: F21V8/00
Filed: 2020-08-24
Abstract: L'invention concerne un procédé de fabrication d'un guide d'ondes. Le procédé consiste à fabriquer un premier outil de réseau maître comprenant un premier substrat d'outil ayant une surface avec une zone correspondant au moins à la zone d'une surface du guide d'ondes et ayant un premier profil de réseau formé sur sensiblement la totalité de la surface du premier substrat d'outil. Le procédé consiste également à fabriquer un second outil de réseau maître comprenant un second substrat d'outil ayant une surface avec une zone correspondant au moins à la zone de la surface du guide d'ondes et ayant un second profil de réseau formé sur sensiblement la totalité de la surface du second substrat d'outil. Le procédé consiste également à utiliser le premier outil de réseau maître pour reproduire le premier profil de réseau sur sensiblement la totalité d'une surface d'un premier substrat de guide d'ondes. Le procédé consiste également à utiliser le second outil de réseau maître pour reproduire le second profil de réseau sur sensiblement la totalité d'une surface d'un second substrat de guide d'ondes. Le procédé consiste également à appliquer une première couche diélectrique sur une zone sélectionnée du premier profil de réseau reproduit sur la surface du premier substrat de guide d'ondes. Le procédé consiste également à appliquer une seconde couche diélectrique sur une zone sélectionnée du second profil de réseau reproduit sur la surface du second substrat de guide d'ondes. Le procédé consiste également à appliquer une couche de matériau de stratification sur au moins l'une des surfaces des premier et second substrats de guide d'ondes et mettre en contact les surfaces des premier et second substrats de guide d'ondes pour assembler ainsi les premier et second substrats de guide d'ondes ensemble par une couche de stratification intermédiaire.
Patent EP-3770587-A1 (EP)
Title: Inspection device, inspection results management system, inspection results storage method, and inspection results management method
Inventor: KAWANISHI NORIO
IPC: G01N21/88
Filed: 2020-02-04
Abstract: An inspection apparatus includes an image-capturing unit configured to capture an image of an article, an inspection unit configured to inspect the article, a generation-processing unit, and a storage-processing unit. The generation-processing unit generates a data group related to an inspection result obtained by the inspection unit, the data group including article information for distinguishing the article, the inspection result obtained by the inspection unit, captured-image information for distinguishing a captured image captured by the image-capturing unit from another captured image, and a hash value of the captured image that are associated with each other. The storage-processing unit stores the data group and the captured image in respective different storage units.
Patent EP-3913719-A1 (EP)
Inventor: KIM HYUN SEUNG
IPC: H01M10/052
Filed: 2020-02-26
Abstract: The present invention relates to an electrolyte for a lithium secondary battery, which includes a lithium salt, a first additive, a second additive, and an organic solvent, wherein the first additive includes a compound represented by Formula 1 and the second additive includes a compound represented by Formula 2, and a lithium secondary battery including the same.
Patent EP-3930742-A1 (EP)
Inventor: POIRIER MICHAEL
IPC: A61K38/17
Filed: 2020-02-26
Abstract: A whole blood treatment device includes a cartridge configured to receive whole blood, having a wall defining an interior volume, an inlet, and an outlet, a support structure having a surface, inside of the cartridge, and an affinity agent, attached to the surface of the support structure. The affinity agent is effective to bind to a target agent that is desirable for removal from a patient. The target agent is selected from the group consisting of: inhibitory checkpoint molecules, inflammatory factors, cancerous cells, autoantibodies, opioids and heavy metals. A method of removing a target agent from whole blood of a patient in a whole blood treatment device comprising pumping whole blood into a cartridge, containing a support structure having a surface, with a plurality of affinity agents on the support structure, to contact the whole blood with the affinity agents; binding the target agent with the affinity agents; and removing the whole blood having a reduced amount of the target agent from the cartridge. The target agent is selected from the group consisting of: inhibitory checkpoint molecules, inflammatory factors, cancerous cells, autoantibodies, opioids and heavy metals.
Patent EP-4027808-A1 (EP)
Inventor: UNGUREANU IOANA MARIA
IPC: C12G3/06
Filed: 2020-09-09
Abstract: A method of improving mouthfeel and masking perceived astringency and undesired off-notes imparted by a consumable composition or additive, including the step of adding to the consumable or additive an astringency-masking amount of hyaluronic acid and/or salt thereof, wherein the hyaluronic acid and/or salt thereof has an average molecular weight of at least 500 kDa. Additionally disclosed is a food or beverage additive comprising at least one astringent component and an astringency-masking amount of hyaluronic acid and/or salt thereof. Further disclosed is a consumable composition comprising a consumable base, at least one astringent component and an astringency-masking amount of hyaluronic acid and/or salt thereof.
Patent EP-4034348-A1 (EP)
Inventor: KORL SASCHA
IPC: B25J9/16
Filed: 2020-09-23
Abstract: The invention relates to a method for specifying a position and/or orientation of an instrument head (10) in a measuring environment (11) by means of a distance measuring device (16) which comprises a number of M, M ≥ 1 distance measuring sensors (18) and which is connected to the instrument head (10). Also comprising a control device (17) which is communicatively connected to the distance measuring device (16) and an on-board sensor device (14), wherein the position and/or orientation of the instrument head (10) has been determined by means of the on-board sensor device (14) and transmitted to the control device (17).
Patent EP-3944031-A1 (EP)
Inventor: NAMIE MASAKI
IPC: G05B13/04
Filed: 2020-03-06
Abstract: A measurement sensor is integrated with a control object so that a position separated from a process object by the control object along a target trajectory is a measurement point. A control device includes: a first generation unit that generates a first command position on a flat surface of the control object; a first control unit that generates a first operation amount using a model prediction control; a second generation unit that generates a second command position on a perpendicular axis that is perpendicular to the flat surface of the control object; and a second control unit that generates a second operation amount using the model prediction control. The second generation unit generates the second command position so that the distance between the control object and the surface of a physical object is constant, based on the measurement result of the measurement sensor and the first command position. The control object thereby follows the shape of the surface of the physical object with good precision.
Patent EP-4045838-A1 (EP)
Inventor: VAN BOMMEL TIES
IPC: F21K9/232
Filed: 2020-10-06
Abstract: La présente invention concerne une lampe à filament à DEL, diode électroluminescente (100), comprenant au moins un filament à DEL (120, 120a, 120b) ayant une partie de base (210) et une partie supérieure (22) s'étendant sur une longueur L, le long d'un axe longitudinal, A, dans laquelle le filament à DEL comprend un réseau d'une pluralité de diodes électroluminescentes, DEL, (140) s'étendant le long de l'axe longitudinal A ; un encapsulant (145) entourant au moins partiellement la pluralité de DEL, l'encapsulant comprenant un matériau luminescent (150). Le réseau linéaire de DEL (140) comprend une pluralité N de DEL bleues (106) émettant de la lumière bleue et une pluralité de M DEL rouges (107) émettant de la lumière rouge, le réseau linéaire de DEL (140) comprenant une densité de DEL bleues et une densité de DEL rouges, la densité de DEL bleues diminue et/ ou la densité de DEL rouges augmente de la partie de base (210) à la partie supérieure (220) le long d'au moins une partie de la longueur (L), moyennant quoi la température de couleur, CT L , de la lumière émise par le ou les filaments à DEL diminue de la partie de base (210) à la partie supérieure (220) sur au moins une partie de la longueur du ou des filaments à DEL.
Patent EP-3954173-A1 (EP)
Inventor: ZHENG RUIMING
IPC: H04W74/08
Filed: 2020-04-08
Abstract: Some techniques and apparatuses described herein provide an indication of a result of decoding a two-step random access channel (RACH) message and an action to be performed by a user equipment (UE). For example, some techniques and apparatuses described herein may provide the indication using a UE contention resolution identity-based approach, wherein the contention resolution identity of the UE may be provided in a random access response. Some techniques and apparatuses described herein may use a fallback indicator that indicates the result of decoding and/or the action to be performed. Some techniques and apparatuses described herein may use a random access response (RAR) subheader that selectively omits a random access preamble identifier based at least in part on the result of decoding and/or the action to be performed.
Patent EP-4028017-A1 (EP)
Inventor: KOESTLER ROLAND
IPC: A61P37/02
Filed: 2020-09-11
Abstract: The present invention relates to compounds of formula (I) that are capable of modulating, e.g., inhibiting or activating, one or more kinases, especially LRRK2 and/or NUAK1 and/or TYK2 or mutants thereof. The compounds are useful for treating diseases, such as autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, Alzheimer's disease, Parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 40 to 146; examples 1 to 63; compounds 1 to 248; tables 1 to 3). Preferred compounds are e.g. 1,4-dihydrobenzo[d]pyrazolo[3,4-f] [1,3]diazepine derivatives and related compounds. An exemplary compound is e.g. 5-(2,6-difluorophenyl)-8-methoxy-1,4- dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine (example 49). (Formula (II)).
Patent EP-4090148-A1 (EP)
Title: Apparatuses for soil and seed monitoring
Inventor: HODEL JEREMY
IPC: A01C5/06
Filed: 2020-09-28
Abstract: A soil apparatus (e.g., a knife) to engage in soil is described herein. In one embodiment, the soil apparatus includes a soil engaging portion to engage with soil and a plurality of sensors disposed in the soil apparatus. Each sensor is independently pivotable to independently position for sensing soil characteristics of soil.
Patent EP-3960444-A1 (EP)
Title: Adhesive and adhesive tape
Inventor: KAWABE SHIGEKI
IPC: B32B27/00
Filed: 2020-04-22
Abstract: Provided are a pressure-sensitive adhesive that is suppressed from being reduced in pressure-sensitive adhesive strength at the time of its contact with an oil content or an alcohol component, and a pressure-sensitive adhesive tape including the pressure-sensitive adhesive. The pressure-sensitive adhesive of the present invention is a pressure-sensitive adhesive configured to express an adhesive property by being pressure-bonded, including: an acrylic polymer having an acid functional group; and a crystalline resin having a melting point of 25°C or more. In one embodiment, the pressure-sensitive adhesive is configured to express the adhesive property by being warmed. In one embodiment, the acrylic polymer having an acid functional group has a constituent unit "a" derived from a (meth)acrylic acid alkyl ester having a linear or branched alkyl group having 4 or more carbon atoms.
Patent EP-4057832-A1 (EP)
Inventor: ALEXANDER MARCELA
IPC: A23L33/19
Filed: 2020-11-11
Abstract: La présente invention concerne des liquides nutritionnels contenant de la caséine micellaire, à haute teneur en protéines, enrichis en polyphénols et un procédé de production de ceux-ci. L'invention concerne en particulier de tels liquides à haute teneur en protéines ayant une viscosité réduite et une tendance réduite à la gélification à froid.
Patent EP-4052261-A1 (EP)
Inventor: SEGLER MARTIN
IPC: G16C20/10
Filed: 2020-10-23
Abstract: A computer-implemented method of designing a molecule and determining a route to synthesise the molecule is provided. The method comprises: receiving one or more desired properties of the molecule; generating one or more candidate molecules using a first machine learning technique that uses the one or more desired properties of the molecule as an input; and for at least one candidate molecule, computing one or more routes to synthesise the candidate molecule using a second machine learning technique.
Patent EP-3966821-A1 (EP)
Title: Memory processing units and methods of computing dot products
Inventor: ZIDAN MOHAMMED
IPC: G11C13/00
Filed: 2020-04-23
Abstract: A memory processing unit can be configured to compute partial products between one or more elements of a first matrix stored in a given row of a memory cell array and sequential bits of one or more elements of a second matrix. The partial products can he calculated first sequentially across the set of rows and second sequentially across the bit positions of the elements of the second matrix. Alternatively, the partial products can he calculated first sequentially across the bit positions of the elements of the second matrix first and second sequentially across the set of rows. The partial products for each column of elements can be accumulated and bit shifted to compute the dot product of the first and second matrix.
Patent EP-3965548-A1 (EP)
Inventor: HEINOLD MARTIN
IPC: A01C7/10
Filed: 2020-05-08
Abstract: A seeding machine (32,100) includes a seeding mechanism (34,130,150) driven by a seeding motor(194,196). A motor command signal is compensated for accelerations based on a wheel based speed of a towing vehicle (10).
Patent EP-4051999-A1 (EP)
Inventor: PERISSE AMELIE
IPC: G06T7/40
Filed: 2020-10-28
Abstract: The present disclosure relates to a computer-implemented method for generating a coating formulation that yields a coating which is, to the eye of a human observer, identical or substantially similar in appearance to a target coating, as well as a device for performing the method.
Patent EP-4204724-A1 (EP)
Inventor: TANFOGLIO GIANPIETRO
IPC: F16K35/00
Filed: 2020-10-07
Abstract: A module (1) for detecting the angular position of the drive shaft (101) of a valve is described. The module comprises a printed circuit (2, 3), which can be positioned in the proximity of a drive shaft of a valve body, or of an extension element thereof or a motor shaft of a valve actuator. The module also comprises one or more magnets (15), which can be fastened to the shaft that imparts the rotations to the valve body, and one or more magnetic sensors (10, 11) supported on the printed circuit, as well as a communication interface (12). The magnetic sensors generate an electrical signal indicating the position of the magnets. The communication interface remotely transmits a corresponding signal/reading. The acquisition of the readings can be carried out at pre-set time intervals, which can be managed according to the requirements of the production process. The detection module is free of wired connections with the outside and is self-powered by at least one battery (4). A valve (100) and an adapter element are also described, which are also provided with the module, and a method for detecting the open state of the valve remotely by means of the module.
Patent EP-4078245-A1 (EP)
Inventor: FU KANG
IPC: G01V1/36
Filed: 2020-10-20
Abstract: Seismic data may provide valuable information with regard to the description such as the location and/or change of hydrocarbon deposits within a subsurface region of the Earth. The present disclosure generally discusses techniques that may be used by a computing system to interpolate or deblend data utilizing a projection on convex sets (POCS) interpolation algorithm. The utilized POCS interpolation algorithm operates in parallel for frequency of a set of frequencies of a seismic frequency spectrum.
Patent EP-4061944-A1 (EP)
Title: Inhibitors of adrenomedullin for the treatment of acute myeloid leukemia by eradicating leukemic stem cells
Inventor: SARRY JEAN-EMMANUEL
IPC: C12N15/113
Filed: 2020-11-20
Abstract: The emergence of cells with drug resistant and/or stem cell features might explain frequent relapses and the poor outcome of patients with acute myeloid leukemia (AML). LSCs are heterogeneous for their phenotypes and their sensitivity to chemotherapeutic agents in vivo. Using in silico and functional approaches, the inventors uncovered that CALCRL is overexpressed in LSCs compared with normal hematopoietic cells. They further demonstrated that the CALCRL ligand adrenomedullin (ADM) is highly expressed in AML cells and that increased transcript level was markedly associated with decreased complete remission rates, 5-year overall and event7free survival. The inventors also showed that CALCRL depletion strongly affected leukemic growth in vivo and increased mice survival. Targeting ADM phenocopies the biological and anti-leukemic effects of the CALCRL depletion. These data highlight the critical role of ADM and disclose a promising therapeutic target to specifically eradicate R-LSCs and overcome relapse in AML.
Patent EP-4061567-A1 (EP)
Inventor: ALMEIDA PEDRO
IPC: B22F12/30
Filed: 2020-11-19
Abstract: Provided are a curved clamping mold and systems and methods using the curved clamping mold for manufacturing objects, especially titanium and titanium alloy objects, by directed energy deposition. The methods include thermally pre-bending the substrate onto which the object is to be manufactured to form a pre-bent substrate, attaching the pre-bent substrate to a jig using the curved clamping mold as an underlying support, pre-heating the substrate, and forming the object on the pre-heated, pre-bent substrate using a directed energy deposition technique.
Patent EP-4049129-A1 (EP)
Title: Verfahren zum verknüpfen von objekten eines steuerprogramms einer steuereinheit eines automatisierungssystems und entwicklungsumgebung
Inventor: GOLDSTEIN SVEN
IPC: G06F8/35
Filed: 2020-11-23
Abstract: Die Erfindung betrifft ein Verfahren (100) zum Verknüpfen von Objekten des Datenkommunikationsstandards Open Platform Communication Unified Architecture OPC UA mit Objekten eines PLC Codes einer Steuereinheit (201) eines Automatisierungssystems (200), umfassend: Einlesen eines OPC UA Nodesets einer Companion Specification in einem Leseschritt (101); Generieren von OPC UA Instanzen der OPC UA Objekttypen des OPC UA Nodesets für das Automatisierungssystem (200) und Zusammenfassen der OPC UA Instanzen in einem OPC UA Instanznodeset in einem Instanziierungsschritt (103); Generieren von PLC Objekten in einem PLC Code eines Steuerprogramms des Automatisierungssystems (200) in einem Objektgenerierungsschritt (105); und Verknüpfen der OPC UA Instanzen des OPC UA Instanznodesets mit PLC Objekten des PLC Codes des Steuerprogramms in einem Verknüpfungsschritt (107). Die Erfindung betrifft ferner eine Entwicklungsumgebung (211) zum Ausführen des Verfahrens (100).
Patent EP-4065392-A1 (EP)
Inventor: REHBEIN DIRK-HEINRICH
IPC: B60G3/28
Filed: 2020-11-24
Abstract: A driven four-link rear axle (1) for a motor vehicle comprises a wheel carrier (2), a longitudinal link (3), an upper transverse link (4) and two lower transverse links (5, 6) for supporting the wheel carrier (2) on a vehicle body, an articulated shaft (7) for transmitting a drive torque to a vehicle wheel (8) which is rotatably mounted on the wheel carrier (2), and a vibration damper (9). The vibration damper (9) engages on the wheel carrier (2) below the wheel center (M) and in front of the wheel center (M) in a direction of travel (F). Said vibration damper (9) extends in front of the articulated shaft (7), and through between a foremost of the lower transverse links (5) and the upper transverse link (4), so as to be inclined in the direction of travel (F), to an engagement point (DO) on the body, wherein, in the installed rest position, the corresponding angle of inclination with respect to the vertical (V) in the direction of travel (F) lies in the range from 20° to 60°, and the attachment point (DO) of the vibration damper (9) on the body lies in this case within the height of the vehicle wheel (8).