baber/WOPTO huggingface dataset:
Patent AT-E278003-T1 (AT)
Inventor: AMBUTER HAL
IPC: C11D3/18
Filed: 1998-11-16
Granted: 2004-10-15
Abstract: The present invention relates to thickened aqueous bleach compositions containing peroxygen bleach. Compositions containing peroxygen bleaches are particularly difficult to thicken with sufficient stability for commercial value. The addition of a rheology stabilizer minimizes the loss of stability over time and enables compositions of varying bleach and pH level to be obtained. These compositions comprise a peroxygen bleach, a polymeric rheology modifying agent, an effective amount of a rheology stabilizing agent, sufficient alkalinity buffering agent, with the remainder being water.The present invention relates to thickened aqueous bleach compositions containing peroxygen bleach. Compositions containing peroxygen bleaches are particularly difficult to thicken with sufficient stability for commercial value. The addition of a rheology stabilizer minimizes the loss of stability over time and enables compositions of varying bleach and pH level to be obtained. These compositions comprise a peroxygen bleach, a polymeric rheology modifying agent, an effective amount of a rheology stabilizing agent, sufficient alkalinity buffering agent, with the remainder being water.
Patent AT-E223315-T1 (AT)
Inventor: GHISALBERTI MARCELLO
IPC: B41F35/00
Filed: 1999-10-27
Granted: 2002-09-15
Abstract: A device for cleaning the outer surface of printing cylinders (2) comprising a pair of rotatable members (9, 11) for unwinding and rewinding a fabric (10), a presser means (12) cooperating with the fabric (10), means (50) for feeding onto the fabric (10) a liquid for cleaning the cylinder (2), and means (51) for feeding drying air onto the rotary cylinder (2), in which the pair of rotatable members (9, 11), the presser means (12) and the detergent liquid feeding means pertain to a cleaning assembly (6) movable by pneumatic drive away from and towards the rotary cylinder (2). <IMAGE>
Patent AT-E358325-T1 (AT)
Inventor: TESTI GIANDOMENICO
IPC: H01H33/44
Filed: 1999-07-14
Granted: 2007-04-15
Abstract: An actuation and control device for opening an electric switchgear, for example circuit breakers, disconnectors, etc., particularly for high and medium voltage transmission and/or distribution network. The device allows to improve manoeuvres of the switchgear from both a mechanical and an electrical point of view, and in particular makes it possible to perform the electrical operation in a synchronous and repeatable manner in relation to the network parameters.  <IMAGE>
Patent AT-E270736-T1 (AT)
Inventor: VAN OPSTAL CORNELIS ADRIANUS P
IPC: B29C35/08
Filed: 1999-07-26
Granted: 2004-07-15
Abstract: The present invention relates to a process and device to manufacture an insulating element, which insulating element consists of a bottom plate (1) provided with a foam material (2), in which foam material one or more ribs (4) are situated, and the process consists of the following steps:     a) the application of a foam material (2) to the bottom plate (1), b) the formation of one or more interspaces (3) in the foam material formed in this way, and c) the placing of ribs (4) in the interspaces formed in this way. Furthermore the present invention relates to an insulating element obtained by such a process, as well as to a roof structure in which one or more of such insulating elements are used.   <IMAGE>   <IMAGE>   <IMAGE>   <IMAGE>
Patent AT-E306148-T1 (AT)
Inventor: PAGE MARTIN GERARD
IPC: H04B1/10
Filed: 1999-06-21
Granted: 2005-10-15
Abstract: A proportional diversity radio system for mobile vehicles includes first and second tuners (15,16) and combats both short time delay multipath and long time delay multipath by mixing separate tuner signals obtained using separate space diversity antennas (12,13). The relative contribution of each tuner signal to a final mixed tuner output is determined in direct relation to their respective signal strength signals and inverse relation to their respective long time delay multipath noise signals. <IMAGE>
Patent AT-E235407-T1 (AT)
Inventor: GALLET PATRICK
IPC: B65G47/08
Filed: 1999-01-25
Granted: 2003-04-15
Abstract: The collector consists of a vibrating table on which the articles to be collected advance in small jumps, and an oscillating rake (3) with two transverse side bars (2). The friction between the articles being collected and the table is fairly low, and the rake performs a transverse reciprocating motion with the lateral bars pushing in turn on the collected articles so that they gather in a space as compact as possible. The distance between the bars is adjusted according to the diameter of the articles and the number of them being collected at one time.
Patent AT-E225274-T1 (AT)
Inventor: BELLI ALESSANDRO
IPC: B62K15/00
Filed: 1999-01-27
Granted: 2002-10-15
Abstract: Foldable two-wheeled vehicle comprising a frame in which there is provided at least one central body (10), at least one group (20) supporting the rear wheel (21), at least one group (60) supporting the front wheel (61) and at least one group (50) for steering the front wheel (61), which are respectively hingeably joined to the central body (10), there being provided means for controlling (70) and actuating (L72,L73,L74, L75,L76) the rotation of groups (20,50,60) around the central body (10), so as to close/open the frame from an open configuration suitable for use to a closed configuration suitable for transportation and vice versa.
Patent AT-E275349-T1 (AT)
Inventor: MORRIS PAUL
IPC: A41B3/10
Filed: 1999-04-14
Granted: 2004-09-15
Abstract: A method of making a fabric composite capable to assuming a desired shape including the steps of forming an interlining fabric (10) containing elastic yarn (15) running longitudinally of the fabric, varying the density of yarn across the width of the interlining to control the longitudinal extensibility across the width, and attaching the interlining to a fabric backing material (12).
Patent AT-E430806-T1 (AT)
Inventor: FUKUMURA MASAYUKI
IPC: A61K48/00
Filed: 1999-07-01
Granted: 2009-05-15
Abstract: Use of a negative-sense RNA virus vector has enabled transfer of nucleic acid into nerve cells. The method of this invention can be used for introducing a gene efficiently into nerve cells including the central nerve tissue in gene therapy, etc.
Patent AT-E298956-T1 (AT)
Inventor: LINDOFF BENGT
IPC: H04L27/01
Filed: 1999-10-04
Granted: 2005-07-15
Abstract: Channel estimation is performed by receiving a received training sequence portion of a radio signal, and estimating a number of channel model structures based on the received training sequence and a predetermined training sequence. For each of the channel model structures, corresponding coefficients are determined by using all of a set of one or more taps associated with the corresponding channel model structure and no others. For each of the channel model structures, a variance measure is generated that represents an amount of variance between an estimated value generated by the channel model structure and a received signal value. An optimum channel model structure is selected from the channel model structures, based on the variance measures, and a number of states associated with the optimum channel model structure is generated. Equalization techniques are then used to generate the decided symbol from the received signal, the optimum channel model structure and the number of states.
Patent AT-E317914-T1 (AT)
Inventor: THAKKER DHIREN R
IPC: G01N33/50
Filed: 1999-11-15
Granted: 2006-03-15
Abstract: A method of screening a candidate compound for susceptibility to metabolism by a selected enzyme. The method includes the steps of reacting the candidate compound, an indicator compound precursor and the selected enzyme, the enzyme characterized as having a side reaction associated with metabolic activity of the enzyme wherein a chemical species capable of reacting with the indicator compound precursor is produced; and detecting an indicator compound, the indicator compound produced from the indicator compound precursor by reaction with the chemical species produced from the side reaction associated with metabolic activity of the enzyme, the detection of the indicator compound indicating the susceptibility of the candidate compound to metabolism by the enzyme. A preferred example of the selected enzyme is a cytochrome P450 (CYP).
Patent AT-E432984-T1 (AT)
Inventor: HUANG LAN-QING
IPC: G01N33/53
Filed: 1999-11-26
Granted: 2009-06-15
Abstract: Polypeptides comprising an unbroken sequence of amino acids from SEQ. ID. NO. 1 or 2, with an ability to complex with a major histocompatibility complex molecule type HLA-A2, and preferably HLA-A2.1.
Patent ES-2234450-T1 (ES)
Title: Calzado con lengueta reversible.
Inventor: JONES LINDELL B
IPC: A43C3/00
Filed: 2002-11-06
Abstract: Un dispositivo para incorporar una lengüeta a un calzado, que comprende un acoplamiento de bola y encaje consistente en una parte de bola incorporada a la lengüeta y una parte de encaje incorporada al calzado, en el que la bola está asegurada giratoriamente dentro del encaje de manera que la lengüeta pueda girar alrededor de un primer eje, sin deformarse mientras permanece incorporada al calzado, para exponer alternativamente un primer y un segundo lado de la lengüeta.
Patent ES-2668986-T1 (ES)
Title: Sistema de expansión de E / S inteligente configurable
Inventor: CAWSE NEIL CHARLES
IPC: H04L12/46
Filed: 2013-04-03
Abstract: Un método de inicialización de un expansor de E / S inteligente (50) y un sistema de soporte físico de telemetría vehicular (30), comprendiendo el método: determinar el tipo de puerto de expansor de E / S, si es serie, establecer tipo serie y modo de expansor pasivo, si es dispositivo auxiliar, establecer tipo dispositivo auxiliar y modo de expansor activo, enviar un mensaje y tipo de puerto al sistema de soporte físico de telemetría vehicular (30), si es serie, enviar un mensaje de consultar dispositivo al expansor de E / S (50) y recibir el tipo de dispositivo, si el tipo de dispositivo es un primer tipo de dispositivo, establecer el sistema de soporte físico de telemetría vehicular (30) a un modo de control serie activo, si el tipo de dispositivo es un segundo tipo de dispositivo, establecer el sistema de soporte físico de telemetría vehicular (30) a un modo de control serie pasivo, si es dispositivo auxiliar, enviar un mensaje con características de supervisión al expansor de E / S (50).
Patent ES-2814953-T1 (ES)
Title: Sistema para proporcionar telemáticamente calificación de componente de vehículo
Inventor: DAVIDSON MARK JEFFREY
IPC: G06K9/62
Filed: 2020-07-16
Abstract: Un sistema para identificar parámetros de estado de salud del componente en tiempo real de un componente de vehículo que comprende: un dispositivo de hardware telemático que comprende un procesador, memoria, firmware y capacidad de comunicaciones; un dispositivo remoto que comprende un procesador, memoria, software y capacidad de comunicaciones; monitorizando dicho dispositivo de hardware telemático al menos un componente de vehículo de al menos un vehículo y registrando datos de componente operacionales de dicho al menos un componente de vehículo, comunicando dicho dispositivo de hardware telemático un registro de datos de componente operacionales a dicho dispositivo remoto; accediendo dicho dispositivo remoto a al menos un registro de datos de componente operacionales, comprendiendo dichos datos de componente operacionales valores operacionales de al menos un componente de vehículo de al menos un vehículo, dichos valores operacionales representativos del uso de ciclo de vida operacional de dicho al menos un componente de vehículo, estando basados adicionalmente dichos valores operacionales en un evento de componente medido; almacenando dicho dispositivo remoto al menos un valor operacional umbral representativo de la salud del componente de vehículo basándose en dicho evento de componente medido; y, asociando adicionalmente dicho dispositivo remoto los datos de componente operacionales y el al menos un valor operacional umbral para identificar los parámetros de estado de salud del componente en tiempo real del componente de vehículo.
Patent ES-2037650-T1 (ES)
Title: Particulas ceramicas revestidas uniformemente.
IPC: C04B35/56
Filed: 1989-12-19
Abstract: SOLIDOS QUE SE SOMETEN A UNA REACCION DELETEREA CON UN MEDIO DE DISPERSION EN EL QUE ESTAN SUSPENDIDOS PUEDEN TRITURARSE DE FORMA SEGURA EN ESE MEDIO DE SUSPENSION SUMINISTRANDO EN EL UN SURFACTANTE CAPAZ DE REACCIONAR CON EL SOLIDO A UNA VELOCIDAD MAYOR QUE LA QUE PUEDE ALCANZAR EL MEDIO DE DISPERSION REACCIONANDO DE TAL FORMA QUE SE SUPRIME LA REACCION DELETEREA. EN PARTICULAR, NITRURO DE SILICIO O CARBURO DE SILICIO DESINTERIZADOS, QUE CUANDO SE PUSIERAN EN CONTACTO CON AGUA SE DESCOMPONDRIAN PARA FORMAR SILICIO EN SUS SUPERFICIES, PUEDE TRITURARSE EN AGUA, SIN PRODUCIR CANTIDADES EXCESIVAS DE SILICIO. LAS DISPERSIONES PRODUCIDAS SON LO SUFICIENTEMENTE ESTABLES COMO PARA FILTRARSE A TRAVES DE ABERTURAS DE 2 MICRONES CON UNA PERDIDA NO MAYOR DEL 5% DEL NITURO O CARBURO DE SILICONA. LAS DISPERSIONES ESTABLES DE SOLIDOS EN LIQUIDOS PUEDEN REVESTIRSE CON UN SOLIDO DISTINTO MEDIANTE PRECIPITACION DE SUPERFICIE BAJO CONDICIONES QUE EXCLUYEN LA FORMACION DE UN PRECIPITADO VOLUMETRICO. ASI, LASPARTICULAS CERAMICAS DE NITRURO O CARBURO SE REVISTEN CON ADITAMENTOS DE DENSIFICACION, COMO ITRIA, POR EL PRECIPITADO DE SUPERFICIE DE LOS HIDROXIDOS CORRESPONDIENTES EN LAS PARTICULAS CERAMICAS EN AGUA. LOS POLVOS DE CERAMICA PREPARADOS DE ESTE MODO SE DENSIFICAN PARA DAR PRODUCTOS CON MODULOS DE RUPTURA Y RESISTENCIAS A LAS FRACTURAS POR LO MENOS TAN ALTAS COMO LA DE LOS POLVOS TRITURADOS DE FORMA CONVENCIONAL EN ALCOHOL CON MENORES CANTIDADES DE ADITAMENTOS DE DENSIFICACION.
Patent CY-1107603-T1 (CY)
Inventor: GIANNI ALESSANDRO MASSIMO
IPC: A61P19/10
Filed: 2007-01-08
Abstract: The invention relates to the field of hematopoietic CD34 +  cell mobilization. In particular, this invention relates to a method for increasing the mobilization of pluripotent hematopoietic CD34 +  cells by administration of human growth hormone or one of its derivates to the individual.
Patent CY-1108099-T1 (CY)
Title: Ενωσεις αμμωνιου κυκλοδεξτρινης μετατραπεισες σε τετρατοταγη δομη
Inventor: KIS GEORG LUDWIG
IPC: A61K47/30
Filed: 2008-05-20
Abstract: Χρήση μιας ένωσης του τύπου (I),όπου το σύμβολο (a) παριστάνει ένα n-σθένους κατάλοιπο το οποίο προέρχεται από μια ένωση κυκλοδεξτρίνης διαμέσου της αφαίρεσης n των υδροξυλο-ομάδων της, το n είναι ένας αριθμός μεγαλύτερος του 0 και παριστάνει τον μέσο αριθμό υποκατάστατων του τύπου (II) ανά μόριο της εν λόγω ένωσης, το h είναι 0 ή 1, το R1 είναι μια δισθενής ομάδα η οποία επιλέγεται από τα αλκυλένιο, υδροξυαλκυλένιο, αλογονοαλκυλένιο, μονοκυκλικό αραλκυλένιο, κυκλοαλκυλένιο και φαινυλένιο, τα R2, R3 και R4 είναι έκαστο ανεξάρτητα από το άλλο μια ομάδα η οποία επιλέγεται από τα αλκύλιο, κυκλοαλκύλιο, αρύλιο, αραλκύλιο και κυκλοετερύλιο, το Xm- είναι ένα m-φορές αρνητικά φορτισμένο ανιόν, το m είναι ένας ακέραιος αριθμός ο οποίος είναι ίσος ή μεγαλύτερος του 1, και το k είναι n/m, στην παρασκευή ενός αντιμολυσματικού φαρμάκου, ως συντηρητικού και ενισχυτή της διαπερατότητας.
Patent CY-1114332-T1 (CY)
Title: Στερεες μορφες του ν-(4-(7-αζαδικυκλο[2.2.1]επταν-7-υλ)-2-(τριφθορομεθυλ)φαινυλ)-4-οξο-5-(τριφθορομεθυλ)-1,4-διυδροκινολινο-3-καρβοξαμιδιου
Inventor: ZHANG BEILI
IPC: A61P11/00
Filed: 2013-06-11
Abstract: Η παρούσα εφεύρεση αναφέρεται σε μορφές στερεάς κατάστασης, για παράδειγμα, κρυσταλλικές μορφές του Ν-(4-(7-αζαδικυκλο[2.2.1]επταν-7-υλ)-2-(τρι-φθορομεθυλ)φαινυλ)-4-οξο-5-(τριφθορομεθυλ)-1,4-διυδροκινολινο-3-καρβοξαμιδίου, σε φαρμακευτικές συνθέσεις του, και σε μεθόδους με αυτό.
Patent CY-1114086-T1 (CY)
Title: Συσκευη εγχυσης τυπου στυλο με θηκη επιλογεα δοσης
Inventor: VEASEY ROBERT FREDERICK
IPC: A61M5/315
Filed: 2013-06-26
Abstract: Η εφεύρεση αναφέρεται σε μια συσκευή έγχυσης τύπου στυλό που περιλαμβάνει ένα περίβλημα (4), μια ράβδο εμβόλου (20) που προσαρμόζεται για να λειτουργεί μέσα από το περίβλημα, μια θήκη επιλογέα δόσης (70) που βρίσκεται μεταξύ του περιβλήματος και της ράβδου εμβόλου, με τη θήκη επιλογέα δόσης να έχει ένα ελικοειδές σπείρωμα (74) μιας πρώτης πορείας, μια θήκη κίνησης (30) που βρίσκεται μεταξύ της θήκης επιλογέα δόσης και της ράβδου εμβόλου, με τη θήκη κίνησης να έχει μια ελικοειδή εγκοπή (38) μιας δεύτερης πορείας, όπου η πρώτη πορεία του ελικοειδούς σπειρώματος (74) και η δεύτερη πορεία της ελικοειδούς εγκοπής (38) είναι ίδιες, όπου παρέχεται ένα περικόχλιο (40) το οποίο μπορεί να περιστρέφεται ως προς τη θήκη κίνησης (30) και μπορεί να μετατοπίζεται αξονικά, αλλά χωρίς να περιστρέφεται ως προς το περίβλημα (4).
Patent CY-1115639-T1 (CY)
Title: Διειδικα αγωνιστικα αντισωματα υποδοχεα θανατου
Inventor: BRUENKER PETER
IPC: C07K16/28
Filed: 2014-10-10
Abstract: Η παρούσα εφεύρεση αναφέρεται σε διειδικά αντισώματα τα οποία περιλαμβάνουν μία πρώτη θέση πρόσδεσης αντιγόνου ειδική για έναν υποδοχέα θανάτου και μία δεύτερη θέση πρόσδεσης αντιγόνου ειδική για ένα δεύτερο αντιγόνο, μεθόδους για την παραγωγή τους, φαρμακευτικές συνθέσεις που περιέχουν τα εν λόγω αντισώματα και χρήσεις αυτών.
Patent CY-1119791-T1 (CY)
Title: Μεθοδος για την παραγωγη καραμελων ζελε με ρευστη γεμιση
Inventor: ZANNI MASSIMILIANO
IPC: A23L29/281
Filed: 2018-01-18
Abstract: Η παρούσα εφεύρεση αφορά καραμέλες ζελέ με μία ρευστή γέμιση και τη μέθοδο παραγωγής αυτών. Το κέλυφος περιέχει πηκτίνη και περικλείει πλήρως τη γέμιση. Αμφότερα το κέλυφος και η γέμιση περιέχουν οξέα-πάντως, η τιμή pΗ της γέμισης είναι χαμηλότερη από αυτήν του κελύφους. Οι καραμέλες ζελέ λαμβάνονται δια εναπόθεσης από ρευστές συνθέσεις με μία διαφοροποιημένη τιμή pΗ.
Patent HR-P20100370-T1 (HR)
Title: Chimeric recombinant antigens of toxoplasma gondii
Inventor: GARGANO NICOLA
IPC: C07K19/00
Filed: 2010-07-01
Abstract: The invention described herein relates to a method for combining antigen fragments of Toxoplasma gondii proteins, in the form of chimeric fusion products, and their use as diagnostic and immunogenic agents.
Patent SI-1418606-T1 (SI)
Title: Electromagnetic relay
Inventor: PLAPPERT FRIEDRICH
IPC: H01H50/04
Filed: 2003-10-31
Abstract: The electromagnetic relay has a rectangular baseplate (10) carrying electric contacts. A bearing carrier (60) may be fastened to it, and incorporates a bearing pin (62) engaging an armature (50) which can carry a coil or a permanent magnet.  The baseplate carries rectangular guide pins (46) which may engage the armature. These pins are fastened to the ends of the casing for the coil (40) there is a central wall (14) in the baseplate assembly.
Patent SI-1345247-T1 (SI)
Title: Fuse assembly
Inventor: LAXTON DAVID
IPC: H01H85/00
Filed: 2003-03-11
Abstract: A fuse assembly is provided, comprising a main fuse element; an indicator fuse element, arranged electrically in parallel with the main fuse element; and an indicator assembly. The indicator assembly comprises an indicator movable between a first position and a second position, a biasing means biasing the indicator to the second position, and the indicator being retained in the first position by the indicator fuse element against the action of the biasing means. The biasing means is may be a helical spring or an arrangement of opposing leaf spring elements. Melting of the indicator fuse element releases the indicator for movement from the first position to the second position, the biasing element acting to provide a biasing force against the indicator fuse element substantially along the line of the retaining force exerted by the indicator fuse element. The general application of leaf spring elements to provide the biasing force for fuse assembly indicator assemblies is also disclosed. <IMAGE>
Patent SI-1557065-T1 (SI)
Title: Method for improving qos mechanisms during bandwith allocation in cdma mobile communication systems
Inventor: KLEO REMI
IPC: H04L12/56
Filed: 2003-10-27
Abstract: The invention relates to a method for improving QoS mechanisms during bandwidth allocation in CDMA mobile communication systems, characterized in that the user terminal signals the minimal bandwidth (bit rate) which is required to the mobile communication system and a bandwith within said range is allocated to the radio interface when available. As a result, the opportunities provided by the user terminal and the bandwith available in the radio cell are used as efficiently as possible.
Patent SI-1754478-T1 (SI)
Title: Liquid Composition comprising arginine and alpha-lipoic acid and its use for improvement of sexual function
Inventor: WESSEL KLAUS
IPC: A61K31/00
Filed: 2005-08-04
Abstract: The present invention relates to solid compositions comprising a substance which improves nitric oxide (NO) availability, re. an NO donor or a precursor of the biosynthesis of nitric oxide or an direct or indirect NO agonist, with arginine being a preferred compound, in combination with a dithiolane, with ±-lipoic acid as a preferred compound, and its use for improvement of sexual function. The compositions according to the invention comprise the NO donor or its precursor in excess, based on the molar amount of the constituents. The compositions are also suited for the improvement of sexual function. In particular the present invention relates to the use of a dithiolane in combination with a NO donor or a precursor thereof for the preparation of a medication for treatment of sexual dysfunction.
Patent SI-1725192-T1 (SI)
Title: Apparatus for mixing and discharging bone cement
Inventor: FOSTER DAVID
IPC: A61F2/00
Filed: 2005-03-08
Abstract: The invention relates to a relatively simple, low cost and effective apparatus for mixing and discharging bone cement into a discharging device such as a syringe, while also providing an improved mixing action and producing minimal fumes. The syringe may be connected to an exit port located between the first and second end of the apparatus. The apparatus is able to both prevent and enable communication between a mixing region of the apparatus and the exit port due to presence of a valve and may further comprise a base which may be integral with the valve so that movement of the base creates movement of the valve within the apparatus.
Patent SI-1966064-T1 (SI)
Title: Improved valve bag
Inventor: FRANSEN ALFONS JOZEF
IPC: B65D83/00
Filed: 2006-12-28
Abstract: The bag valve for aerosol cans has a flexible bag (4) which is rolled around the valve (6) but elongates as it is filled. It has flaps (16) at the base which are folded inwards and is held in the rolled position by a label (7) with rupturable perforated lines (17).
Patent DE-3382786-T2 (DE)
Inventor: SUN HYUK KIM
IPC: C07D239/70
Filed: 1983-12-29
Granted: 1995-08-31
Abstract: Novel compounds, and their use in the treatment and prophylaxis of viral infections, are described. 
<??>In one aspect, the compounds have the general formula: 
<CHEM>
 wherein each R<2>, independently, is H or lower (fewer than 6 carbon atoms) alkyl; each R<3>, independently, is H or lower alkyl, R<0> is H or lower alkyl, R<1> is H or lower alkyl; 1</=n</=11 n-2</=m</=2n; 0</=p</=3; z is 0 or 1; and p</=q</=2p; each n, m, p and q being selected so that the sp<3> valence shell of each carbon atom in each ring is filled; or a pharmaceutically acceptable salt thereof.