baber/WOPTO huggingface dataset:
Patent MX-341531-B (MX)
Title: Sgc stimulators.
Inventor: THOMAS WAI-HO LEE
IPC: A61K31/497
Filed: 2011-11-02
Abstract: Compounds of Formula (IA) and Formula (IB) are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.
Patent MX-339403-B (MX)
Title: Use of a nitrogen- free peroxygen- releasing compound to reduce growth of contaminant microorganisms in ethanol fermentation.
Inventor: SOLOMON ETHAN BARUCH
IPC: C12P7/08
Filed: 2011-12-20
Abstract: A method for controlling growth of contaminant microorganisms in a fermentation process using a nitrogen-free peroxygen-releasing compound. The method comprises adding the nitrogen-free peroxygen-releasing compound to one or more steps of a fermentation process. In this method, the a nitrogen-free peroxygen-releasing compound may be added to one or more components of a fermentation broth comprising inoculant, fermentable sugar and process water.
Patent MX-365065-B (MX)
Title: Enclosure for the permanent repair of leaking and non-leaking faults in ducts.
Inventor: ALFREDO MORALES REYES
IPC: F16L55/172
Filed: 2013-07-19
Abstract: The present invention consists in a mechanical enclosure for the repair of leaks and the corresponding permanent repair of ducts for transporting hydrocarbons, this invention being applied to land and sea ducts. The enclosure in its temporal phase provides response to the operation condition known as leak before being a fault, and allows the client to provide an immediate response before an emergency situation avoiding expensive interruptions in the production. The temporal repair is designed for simplifying the corrective maintenance at short term, allowing the leak to be sealed and increasing the level of pressure according to the operative limit. The mechanical function of the permanent enclosure with the refilling resin of the annular space is to dampen the force transfer from the conductor tube to the enclosure, achieving with this two important characteristics of the enclosure system from the mechanical point of view. The first characteristic is that the force in the enclosure i s maintained at levels lower than those of the conductor tube and the second characteristic being that the resin avoids the expansion of the localized defects, this preventing the faults. The repair carried out by the present invention is performed without interrupting the production, thus removing the leak and repairing the same in a permanent manner.
Patent MX-344354-B (MX)
Title: Compositions and methods for inhibiting expression of transthyretin.
Inventor: STUART MILSTEIN
IPC: C12N15/113
Filed: 2009-10-20
Abstract: The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a transthyretin (TTR) gene, and methods of using the dsRNA to inhibit expression of TTR.
Patent MX-366675-B (MX)
Title: Composition of protectors of acute and chronic hepatic encephalopathy and method for treating acute and chronic hepatic encephalopathy.
Inventor: VLADIMIR VLADIMIROVICH DYNNIK
IPC: A61P25/00
Filed: 2012-05-04
Abstract: The invention relates to medicine and concerns compositions (formulations) which can be, inter alia, in the form of biologically active additives and have the properties of hepatoprotectors and protectors against hepatic encephalopathy: - acute (fulminant) hepatic encephalopathy caused by acute liver failure; - chronic hepatic encephalopathy with an etiological basis of cirrhosis of the liver caused by alcoholic, non-alcoholic or viral hepatitis etc. The invention consists in that: in order to treat acute and chronic hepatic encephalopathy, combination formulations are proposed comprising components having a synergetic activity on different metabolic and signaling systems, including activation of: osmoprotector and energy systems, systems of reactions to detoxification of an ammonium ion and other toxins, and the antioxidant systems of cells of the brain, the liver and other tissues and organs. The formulations for the treatment of acute hepatic encephalopathy comprise, as base: L-carnitine, acetyl-L-carnitine and creatine phosphate, and can also comprise: N-acetylcysteine and ethanol (1); succinate, L-glutamate, L-arginine, L-acetylcysteine and trimethylglycine (2); succinate, L-glutamate, L-arginine and trimethylglycine (3). The formulations for the treatment of chronic hepatic encephalopathy comprise, as base: L-carnitine, acetyl-carnitine, succinate, L-glutamate, L-arginine, trimethylglycine and creatine phosphate, and can also comprise: L-acetylcysteine, coenzyme Q10 and dihydroquercetin (4); S-adenosyl methionine, coenzyme Q10 and dihydroquercetin (5); S-adenosyl methionine, coenzyme Q10, dihydroquercetin and lipoamide (6). The invention extends the range of agents with high hepatoprotector and anti-encephalopathic activity and agents inhibiting the development of a coma and a fatal outcome in the case of acute hepatic encephalopathy and ensuring a reverse development of behavioural, neurological and mental disorders in the case of chronic encephalopathy.
Patent MX-349886-B (MX)
Title: Anti-pseudomonas psl binding molecules and uses thereof.
Inventor: ANTONIO DIGIANDOMENICO
IPC: A61K39/395
Filed: 2012-06-08
Abstract: This disclosure relates to an anti-Pseudomonas Psl binding molecules and uses thereof, in particular in prevention and treatment of Pseudomonas infection. Furthermore, the disclosure provides compositions and methods for preventing and treating Pseudomonas infection.
Patent MX-351869-B (MX)
Title: Vaccination method using the application of volatile organic compounds in carica papaya for the biocontrol of plagues.
Inventor: MARTHA ELENA DE COSS FLORES
IPC: A01C21/00
Filed: 2014-01-07
Abstract: The inventive method consists in applying the concentrations of mixtures of the following Volatile Organic Compounds to healthy Carica papaya plants: 1. 1,3, dichlorobenzene, 2. benzyl alcohol, 3. 2-nonen-1-ol, 4. Benzyl isocyanate, 5. Benzyl nitrilate, 6. Cyclodecanol, 7. 2,3 dichloroanisol, 8. benzyl isothiocyanate, for inducing natural resistance in plants and their effects against plagues and diseases. Healthy plants are early induced by these VOC’s to protect themselves from plagues and diseases, producing transcriptional changes in plants and being susceptible to be genetically and transgenically manipulated. The concentrations are applied to the different parts of the plant, and the seeds and propagules for unchaining the defense responses of the plants; for example, the application may be performed as a seed coating, irrigation water, filters, foliar spray and pulverizations. The benefits also include the response in the improvement of the seeds, propagules and plants. It is a technology in the agriculture derived from the Chemical Ecology field, since there is a direct response (resistance), an indirect response (attractant of natural enemies) and a communication between plants as important points for the early vaccination, amongst other benefits for other crops.
Patent MX-352948-B (MX)
Title: Sulphuric acid production with recycle of desulphurized gas.
Inventor: LYKKE MADS
IPC: C01B17/90
Filed: 2012-09-27
Abstract: The invention relates to a process for oxidation of SO2 to SO3 comprising the steps of (a) directing a stream of feed gas comprising SO2 and O2 to a catalytically active material, (b) oxidizing an amount of said SO2 in said process gas to SO3 in the presence of the catalytically active material, providing a first oxidized process gas, (c) reacting SO3 with water, (d) condensing H2SO4, (e) withdrawing a first desulphurized process gas and a first stream of sulphuric acid, (f) from the desulphurized process gas withdrawing a recycle stream of desulphurized process gas, wherein the recycle stream is added to said stream of feed gas or said first oxidized process gas with the associated benefit of reducing the molar flow of process gas downstream withdrawal of the recycle stream and upstream the mixing point.
Patent MX-341504-B (MX)
Title: Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors.
Inventor: SUNIL KUMAR KC
IPC: A61K31/415
Filed: 2012-09-13
Abstract: lndazole-3-carboxamide compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an indazole-3- carboxamide compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
Patent MX-340989-B (MX)
Title: Recessed light fixture with two-axis rotational arm.
Inventor: DOUG HIGHBRIDGE
IPC: F21V21/04
Filed: 2014-04-07
Abstract: An illustrative embodiment of a light fixture, which may be a type of recessed downlight called a wallwasher, includes a light housing and has a power supply, such as a driver and/or electrical junction box, mounted on or forming an arm. The arm is rotationally coupled to the light housing, with the arm having two axes of rotation relative to the light housing. That is, the arm freely rotates laterally about a first axis, and freely rotates in elevation about a second axis.
Patent MX-342464-B (MX)
Title: Determining an elastic model for a geologic region.
Inventor: STEWART ARCHER
IPC: G01V1/48
Filed: 2013-01-11
Abstract: A technique includes determining at least one impulse response of a modeling and migration of at least one point scatterer in a target structure and based at least in part on the impulse response(s) and a reflection amplitude image, determining a model for at least part of the target structure.
Patent MX-346755-B (MX)
Title: System and method for monitoring weld quality.
Inventor: JOSEPH A DANIEL
IPC: B23K9/095
Filed: 2013-04-23
Abstract: An arc welding system and methods. The system is capable of monitoring variables during a welding process, according to wave shape states, and weighting the variables accordingly, detecting defects of a weld, diagnosing possible causes of the defects, quantifying overall quality of a weld, obtaining and using data indicative of a good weld, improving production and quality control for an automated welding process, teaching proper welding techniques, identifying cost savings for a welding process, and deriving optimal welding settings to be used as pre-sets for different welding processes or applications.
Patent MX-356347-B (MX)
Title: Human antibodies and specific binding sequences thereof for use in stroke and ischemia or ischemic conditions.
Inventor: RODRIGUEZ MOSES
IPC: A61K51/10
Filed: 2013-04-17
Abstract: Specific binding members, particularly human antibodies, particularly recombinant antibodies, and fragments thereof, which are capable of binding to and recognizing neurons in the CNS and eliciting responses in CNS neurons are provided. The antibodies are useful in the diagnosis and treatment of conditions associated with nerve damage, injury or degeneration and neurodegenerative disease, and in particular in the treatment or alleviation of stroke or cerebral ischemia. The antibodies, variable regions or CDR domain sequences. thereof, and fragments thereof of the invention may also be used in therapy in combination with chemotherapeutics, immune modulators, or neuroactive agents and/or with other antibodies or fragments thereof. The antibodies or active fragments thereof may be used in therapy for stroke or cerebral ischemia alone or in combination with thrombolytics such as TPA. Antibodies are exemplified by the antibodies lgM12 and lgM42 whose sequences are provided herein.
Patent MX-347938-B (MX)
Title: A user interface to provide commentary upon points or periods of interest in a multimedia presentation.
Inventor: SANTOSH S BASAPUR
IPC: H04N21/478
Filed: 2013-04-09
Abstract: Disclosed are methods and apparatus for displaying a plurality of presentation elements to a user. A progress bar (54) is displayed. A length of the progress bar (54) is representative of a duration of a multimedia presentation. A communication box (58) is also displayed. The communication box (58) comprises a marker (68) and a communication (59) composed by an originator in relation to a certain point or time period within the multimedia presentation. The progress bar (54) and the communication box (58) are displayed such that the marker (68) is in alignment with a position along the length of the progress bar (54) that corresponds to the point or time period in the multimedia presentation in relation to which the communication (59) was composed. The marker (68) may be moved (s54) relative to the progress bar (54).
Patent MX-365099-B (MX)
Title: Antibodies recognizing alpha-synuclein.
Inventor: BARBOUR ROBIN
IPC: C07K16/18
Filed: 2013-10-08
Abstract: The invention provides monoclonal antibody 5C1 and related antibodies. The 5C1 antibody binds to an epitope within residues 118-126 of a-synuclein. The antibodies of the invention are useful, for example, for treating and/or diagnosing disorders associated with a-synuclein, particularly accumulation of a-synuclein deposits. Such disorders include Lewy body diseases, such as Parkinson's disease, Diffuse Lewy Body Disease (DLBD), Lewy body variant of Alzheimer's disease (LBV), Combined Alzheimer's and Parkinson disease, pure autonomic failure and multiple system atrophy (MSA).
Patent MX-354118-B (MX)
Title: Method and apparatus for forming discrete adjustable pant-like disposable undergarments.
Inventor: BRADLEY WILLIAM SCHOON
IPC: A61F13/505
Filed: 2013-12-11
Abstract: A method and apparatus for producing a pre-fastened adjustable pant-like disposable absorbent undergarment including a fully or partially severed front body panel is disclosed. The method includes first providing a discrete undergarment moving longitudinally in a machine direction. A first panel and second panel are separated in a z- direction to allow for a transport support structure to be passed through a waist opening and a pair of leg openings. While on the transport support structure, the first panel is cut to define a first portion of the front panel and a second portion of the front panel. Finally, the first portion of the front panel and the second portion of the front panel may be joined together with a fastener assembly that connects the first portion and the second portion.
Patent MX-366784-B (MX)
Title: Method for producing a liquid emulsifiable formulation comprising a pyripyropene pesticide.
Inventor: RALPH PAULINI
IPC: A01N25/30
Filed: 2014-01-15
Abstract: The present invention relates to a method for producing a liquid non-aqueous emulsifiable formulation comprising a pyripyropene pesticide of the formula (I) as defined below which is dissolved in an aromatic hydrocarbon or hydrocarbon mixture containing surfactants, which stabilize the emulsion upon dilution with water, which method comprises the steps i) and ii) as described hereinafter: i) dissolving the at least one surfactant and the compound of formula (I) in the organic solvent or solvent mixture to obtain a clear solution of the at least one surfactant and the compound of the formula(I); ii) heating the solution to a temperature of at least 40°C.
Patent MX-363950-B (MX)
Title: Urea derivatives useful as kinase inhibitors.
Inventor: MEGHANI PREMJI
IPC: C07D405/12
Filed: 2014-04-01
Abstract: There are provided compounds of formula I, wherein R1A to R1E, R2 to R5, L and X1 to X3 have meanings given in the description, which compounds have antiinflammatory activity (e.g. through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.
Patent MX-361798-B (MX)
Title: Continuous process for the manufacture of highly-branched polymers based on c3-c8 monoethylenically unsaturated mono- or dicarboxylic acid or on the anhydrides and salts thereof.
Inventor: HELMUT WITTELER
IPC: B01F13/00
Filed: 2014-04-07
Abstract: The present invention relates to a continuous process for the manufacture of highly-branched homo- or copolymers of C3-C8 ethylenically unsaturated mono- or dicarboxylic acid as well as the anhydrides and salts thereof (monomer A) by means of free-radical polymerization of monomer A and optionally water-soluble, monethylenically unsaturated comonomers (monomer B) in an aqueous medium in the presence of at least one water-soluble initiator, wherein the polymerization takes place in at least one tubular reactor segment.
Patent MX-360090-B (MX)
Title: Terminal for performing fingerprint recognition.
Inventor: ANYU LIU
IPC: G06K9/62
Filed: 2015-09-24
Abstract: A terminal for performing fingerprint recognition, which falls within the technical field of computers. The terminal comprises a fingerprint recognizer (1), a processor (2), a body (3) and a plurality of fingerprint detection units (4), wherein the plurality of fingerprint detection units (4) are distributed between a screen cover plate (5) of the body (3) and a screen; the fingerprint recognizer (1) is arranged inside the body (3), electrically connected to the plurality of fingerprint detection units (4) respectively and electrically connected to the processor (2), and is used for acquiring a detection signal of each of the fingerprint detection units (4), generating fingerprint data according to the detection signal of each of the fingerprint detection units (4) and sending the fingerprint data to the processor (2); and the processor (2) is arranged inside the body (3) and is used for comparing the fingerprint data with pre-stored reference fingerprint data, and if the fingerprint data matches the reference fingerprint data, executing a pre-set control instruction. By means of this solution, the intensity of the cover plate (5) can be improved.
Patent MX-367085-B (MX)
Title: Pyridines, pyrimidines, and pyrazines, as btk inhibitors and uses thereof.
Inventor: LESLEY LIU-BUJALSKI
IPC: C07D487/04
Filed: 2014-07-30
Abstract: The present invention relates to pyridine, pyrimidine, and pyrazene compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.
Patent MX-363954-B (MX)
Title: Circuit breakers having enlarged pressure relief valves and related electrical distribution panels and systems.
Inventor: JAMES G MALONEY
IPC: H01H9/04
Filed: 2014-10-28
Abstract: Circuit breakers are provided including a pressure release valve. The pressure release valve includes a vent portion and barrier portion. The barrier portion is configured to open when exposed to excessive heat generated by an arc and allow gases to escape from the circuit breaker. Related electrical distribution panels and systems are also provided.
Patent MX-370151-B (MX)
Title: Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors.
Inventor: STEPHEN JOSEPH SHUTTLEWORTH
IPC: A61P35/02
Filed: 2015-02-12
Abstract: A compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein: W is O, N-H, N-(C1 -C 10 alkyl) or S; each X is independently CH or N; R1 is a 5 to 7-membered saturated or unsaturated, optionally substituted heterocycle containing at least 1 heteroatom selected from N or O; R2 is LY; each L is a direct bond, C1 -C 10 alkylene, C2 -C10 alkenylene or C2 -C 10 alkynylene; Y is an optionally substituted fused, bridged or spirocyclic non-aromatic 5-12 membered heterocycle containing up to 4 heteroatoms selected from N or O; and each R3 is independently H, C1-C 10 alkyl, halogen, fluoro C1 -C10 alkyl, O- C1 -C10 alkyl, NH-C1 -C10 alkyl, S-C1 -C10 alkyl, O- fluoro C1 -C10 alkyl, NH-acyl, NH-C(O)-NH-C1 -C10 alkyl, C(O)-NH-C1 -C10 alkyl, aryl or heteroaryl, are useful as inhibitors of the class IA phosphoinositide 3- kinase enzyme, PI3K-p110d, and therefore have potential utility in the therapy of cancer, immune and inflammatory diseases.
Patent MX-352958-B (MX)
Title: Decoding device, and decoding method.
Inventor: KAZUSHI SATO
IPC: G06K9/36
Filed: 2014-12-19
Abstract: This technology relates to a decoding device and a decoding method with which the amount of information related to information identifying reference images can be reduced. In cases when an image to be coded is an image other than the first image in a group of pictures (GOP), a reception unit receives "inter_ref_pic_set_prediction_flag" indicating that previously transmitted reference-image-identification information, which identifies a reference image used to generate a prediction image, for an image anterior in coding order to the image to be coded is to be used as the reference-image-identification information for the image to be coded. This technology is applicable to decoding devices or the like for the high-efficiency-video-coding (HEVC) format.
Patent MX-362329-B (MX)
Title: Random seed entry number to eliminate key sequence capture.
Inventor: DRY ALAN GEORGE
IPC: B60R25/23
Filed: 2017-01-25
Abstract: A vehicle entry system includes a lock mechanism, an interface, and a control. The control receives a plurality of code digits by presenting a displayed number on the interface that is initially a random number and at least one of changing or receiving an entry of the displayed number based on a signal from the input. When the plurality of code digits corresponds to a stored entry code, the control causes the lock mechanism to unlock.
Patent MX-370182-B (MX)
Title: 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one compounds and their use as negative allosteric modulators of mglur2 receptors.
Inventor: ANDRÉS-GIL JOSÉ IGNACIO
IPC: A61K31/506
Filed: 2015-07-30
Abstract: The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 ("mGluR2"). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of disorders in which the mGluR2 subtype of metabotropic receptors is involved.
Patent MX-371153-B (MX)
Title: New compounds as nik inhibitors.
Inventor: MONTANA JOHN GARY
IPC: C07D471/04
Filed: 2015-10-22
Abstract: The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-Ä¸B-inducing kinase (NIK - also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.