baber/WOPTO huggingface dataset:
Patent DE-69736950-T2 (DE)
Inventor: COOLER B
IPC: C07F9/6558
Filed: 1997-09-11
Granted: 2007-09-20
Abstract: Novel tricyclic compounds of formula (1.0) or a pharmaceutically acceptable salt or solvate thereof, wherein: one of a, b, c, and d represents N or NR<9>, wherein R<9> is O-, -CH3 or -(CH2)nCO2H wherein n is 1 to 3, and the remaining a, b, c and d groups represent CR<1> or CR<2>; or each of a, b, c and d is independently selected from CR<1> or CR<2>; each R<1> and each R<2> is independently selected from H, halo, -CR3, -OR<10>, -COR<10>, -SR<10>, -S(O)tR<11> (wherein t is 0, 1 or 2), -SCN, -N(R<10>)2, -NR<10>R<11>, -NO2, -OC(O)R<10>, -CO2R<10>, -OCO2R<11>, -CN, -NHC(O)R<10>, -NHSO2R<10>, -CONHR<10>, -CONHCH2CH2OH, -NR<10>COOR<11>, -SR<11>C(O)OR<11>, -SR<11>N(R<75>)<2>; n is 0 (zero), 1, 2, 3, 4, 5 or 6; T is -CO-; -SO-; -SO2-; or -CR<30>R<31>-; Z represents alkyl, aryl, aralkyl, heteroalkyl, heteroaryl, heteroarylalkyl, heterocycloalkyl, heterocycloalkylalkyl, -OR<40>, -SR<40>, -CR<40>R<42>, -NR<40>R<42>, formulae (i), (ii), (iii), (iv), (v) and (vi). Pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel tricyclic compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human.
Patent DE-69801763-T2 (DE)
Inventor: ARIENTE MARC
IPC: H05B6/64
Filed: 1998-07-29
Granted: 2002-05-29
Abstract: The invention concerns a baking dish (1) for a microwave oven comprising in its flat part at least two levels of thickness (2, 3), i.e. a thickness (2) made from a non-heat producing material whereof the outer surface (2a) is designed to be in contact with the food to be cooked, and a layer or thickness (3) forming a peripheral edge made of substantially non-heat conducting elastomer. The invention is characterised in that said dish (1) has at least in its flat part (1a) a monolithic flexible composite structure, comprising an outer layer (3) made of substantially non-heat conducting elastomer, an inner layer (2) made of substantially heat conducting elastomer, and a heat-producing material (4) provided and flatly spread in said monolithic composite structure, the inner and outer layers being directly or indirectly connected with each other, particularly by their respective peripheral edges (3c, 2c).
Patent DE-69811867-T2 (DE)
Inventor: KELLY ALFRED
IPC: C07D401/10
Filed: 1998-03-03
Granted: 2003-11-20
Abstract: A method treating or preventing inflammatory and immune cell-mediated diseases by the administration of certain novel and known small molecules. Exemplary of the novel compounds are those of structural formulas (a), (b), (c), (d), (e) and (f).
Patent DE-69900508-T2 (DE)
Inventor: LANGELIN RENE
IPC: D21H17/67
Filed: 1999-05-27
Granted: 2002-07-18
Abstract: The invention concerns an aqueous suspension of precipitated calcium carbonate particles, said suspension having a pH stabilised at a value less than 9, said calcium carbonate particles containing an agent for obtaining a positive zeta potential of the calcium carbonate particles, the agent for obtaining a positive zeta potential being a substance causing Ca<++> ions to dissolve.
Patent DE-69907605-T2 (DE)
Inventor: VRISSIMDJIS CONSTANTINE SOLON
IPC: A41D19/00
Filed: 1999-11-17
Granted: 2003-12-18
Abstract: Glove of rubber or other resilient material comprising of an essentially tubular sleeve portion (1) and a cuff portion (2) which extends conically outwardly in extension of the sleeve portion and can be folded back such that the free end of the connically outwardly extending cuff portion (2) has a radial distance from the outer circumference of the sleeve portion (1), characterized in that a thinner wall portion (3) having a wall thickness smaller than the wall thickness of at least the sleeve portion (1) is provided between sleeve portion (1) and cuff portion (2), whereas the thinner wall portion (3) is either a thinner extension of the sleeve portion (1) or has the shape of an inwardly directed undulation, wherein the cuff portion (2) is foldable back about the said thinner wall portion (3).   <IMAGE>
Patent DE-69922407-T2 (DE)
Inventor: DE JONGE JOHAN
IPC: C09J133/04
Filed: 1999-07-21
Granted: 2005-12-01
Abstract: The present invention relates to pressure-sensitive removable adhesives based on polyacrylates, characterized in that they comprise a compound of formula:wherein R1, R2 and R3, which are identical or different, represent a linear or branched C1-C8, preferably C2-C6, alkyl radical; and R4 represents H or an acyl radical COR5 wherein R5 is a linear or branched C1-C3 alkyl radical. The present invention also relates to a process for the preparation of said adhesives. The present invention further relates to adhesive labels and tapes comprising said adhesives.
Patent DE-69933589-T2 (DE)
Inventor: ITO TADAYUKI
IPC: G01C11/06
Filed: 1999-06-09
Granted: 2007-08-16
Abstract: The present invention relates to an image forming apparatus comprising:  a control point measuring section for measuring a centrally projected image having a plurality of control points, and obtaining the image coordinates for said control points; a coordinate transformation parameter calculating section for obtaining a transformation parameter for correlating, based on said image coordinates for said control points obtained by said control point measuring section and the three-dimensional coordinates for actually measured control points, said image coordinates with said three-dimensional coordinates; and an ortho-image forming section for forming an orthogonally projected image from said centrally projected image based on said transformation parameter obtained by said coordinate transformation parameter calculating section; characterized in that an ortho-image correcting section is provided for correcting the image coordinates obtained by said ortho-image forming section based on the three-dimensional coordinates for actually measured, additional points, and then performing correction of said orthogonally projected image.  <IMAGE>
Patent DE-69936730-T2 (DE)
Inventor: LEWIS DAVID
IPC: A61L9/04
Filed: 1999-11-22
Granted: 2008-04-30
Abstract: In a solution composition for use in an aerosol inhaler which comprises an active material, a propellant containing a hydrofluoroalkane, a cosolvent and optionally a low volatility m compound the use of a mixture of HFA 134a and HFA 227 allows to modulate the mass median aerodynamic diameter (MMAD) of the aerosol particles on actuation of the inhaler to target specific regions of the respiratory tract. Moreover the fine particle dose (FPD) of the active ingredient in the composition increases by reducing the metering chamber volume.
Patent HU-E026804-T2 (HU)
Title: Inhaler component
Inventor: BUCHBERGER HELMUT
IPC: A24F40/44
Filed: 2012-02-02
Abstract: The invention relates to an inhaler component for forming a vapor-air mixture and/or condensation aerosol by vaporizing a liquid material and optionally condensing the vapor formed, including: a heating element for vaporizing a portion of the liquid material; a wick for automatically supplying the liquid material to the heating element, wherein the wick includes at least two end sections arranged apart from each other; a first capillary gap for automatically supplying the liquid material to the wick, wherein a first end section of the wick projects into the first capillary gap. In order that the heating element can be supplied more quickly and more reliably with the liquid material, a second capillary gap is provided, which receives therein the second end section of the wick.
Patent TR-200000063-T2 (TR)
Title: Esnek soğutucu ortam için ıslatma ve dondurma tesisi.
Inventor: MURRAY JOSEPH C
IPC: F25D13/06
Filed: 1998-07-10
Abstract: Isiya hassas maddelerin kullanimi için ambalaj maddelerinin hazirlanmasi için cihaz, bir hidrasyon (=islatma) modülünü (11), bir dondurucu modülünü (40) ve bir besleme modülünü (45) kullanir. Polimer bazli sogutucu ortamin (117), seçilmis uzunlukta ve genislikteki sürekli ag seklindeki süper emici rulolari, kuru saklama kosullari altinda tutulurlar.
Patent TR-200200926-T2 (TR)
Title: Isıyla şekillendirilebilen poliamidler.
Inventor: POPHUSEN DIRK
IPC: C08K3/00
Filed: 2000-09-26
Abstract: Bu bulus, cam lifiyle takviye edilmis poliamidlere ve bunlarin isiyla sekillendirme için  kullanilmasina iliskindir.
Patent TR-200500745-T2 (TR)
Inventor: HENNEQUIN LAURENT FRANCOIS AND
IPC: C07D403/12
Filed: 2000-02-08
Abstract: The invention relates to the use of compounds of the formula I:   
wherein ring C is an 8, 9, 10, 12 or 13-membered bicyclic or tricyclic moiety which optionally may contain 1-3 heteroatoms selected independently from O, N and S; Z is -O-, -NH-, -S-, -CH 2 - or a direct bond; n is 0-5; m is 0-3; R 2  represents hydrogen, hydroxy, halogeno, cyano, nitro, trifluoromethyl, C 1-3 alkyl, C 1-3 alkoxy, C 1-3 alkylsulphanyl, -NR 3 R 4  (wherein R 3  and R 4 , which may be the same or different, each represents hydrogen or C 1-3 alkyl), or R 5 X 1 - (wherein X 1  and R 5  are as defined herein; R 1  represents hydrogen, oxo, halogeno, hydroxy, C 1-4 alkoxy, C 1-4 alkyl, C 1-4 alkoxymethyl, C 1-4 alkanoyl, C 1-4 haloalkyl, cyano, amino, C 2-5 alkenyl, C 2-5 alkynyl, C 1-3 alkanoyloxy, nitro, C 1-4 alkanoylamino, C 1-4 alkoxycarbonyl, C 1-4 alkylsulphanyl, C 1-4 alkylsulphinyl, C 1-4 alkylsulphonyl, carbamoyl,  N- C 1-4 alkylcarbamoyl,  N , N -di(C 1-4 alkyl)carbamoyl, aminosulphonyl,  N -C 1-4 alkylaminosulphonyl,  N , N -di(C 1-4 alkyl)ammosulphonyl,  N -(C 1-4 alkylsulphonyl)amino,  N- (C 1-4 alkylsulphonyl)- N -(C 1-4 alkyl)amino,  N , N -di(C 1-4 alkylsulphonyl)amino, a C 3-7 alkylene chain joined to two ring C carbon atoms, C 1-4 alkanoylaminoC 1-4 alkyl, carboxy or a group R 56 X 10  (wherein X 10  and R 56  are as defined herein); and salts thereof, in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals, processes for the preparation of such compounds, pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof as active ingredient and compounds of formula I. The compounds of formula I and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.
Patent DE-602004008306-T2 (DE)
Inventor: PRATT ANTHONY RICHARD
IPC: H04L27/26
Filed: 2004-09-01
Granted: 2008-05-08
Abstract: A method of generating a subcarrier modulation signal adapted to modulate a ranging signal of a satellite positioning system. The method comprises a step of multiplexing in the time domain portions of a BOC (5,1) and a BOC (1,1) subcarriers to produce the subcarrier modulation signal. The time multiplex can be used to influence the location of the spectral peaks associated with the BOC subcarriers within the spectrum of the subcarrier modulation signal.
Patent DE-602005001318-T2 (DE)
Inventor: GASS RAYMOND
IPC: H04L29/06
Filed: 2005-03-07
Granted: 2008-02-07
Abstract: A method to provide lawful interception of a device in a network, the network comprising means to define Virtual Local Area Networks (VLAN), characterized in that a lawful interception device of the network defines a Virtual Local Area Network where at least the device to intercept and the lawful interception device are members.
Patent DE-60019076-T3 (DE)
Inventor: JACOBS ANDRE MARIE GUSTAF
IPC: B29C69/00
Filed: 2000-01-07
Granted: 2009-06-18
Abstract: The present invention is directed to a one-piece dosing cap comprising a top wall (13), side walls (20) defining the top portion (15) of a dosing compartment, and an attaching skirt (11) extending from the base of the side walls, said skirt comprising substantially vertical walls and a stopping portion (21), characterized in that said dosing cap comprises at least one undercut portion (21). Preferably, the one-piece dosing cap of the present invention is manufactured by a one-step injection molding process. Also preferably, said cap comprises attachment means for securing, more preferably releasably securing said cap onto the neck of a container. More preferably, said attachment means are achieved by screw threads (12), which match cooperating screw threads of the container. <IMAGE>
Patent DE-69814257-T3 (DE)
Inventor: ROUSSEAU ALAIN
IPC: H02H7/24
Filed: 1998-07-30
Granted: 2012-11-08
Abstract: The device has spark gaps (E1,E2) connected the neutral (N) and earth (T), as well as variable resistors (V10, V11, V12) inserted between the lines of the phases and earth. The phase line (ph, Ph1, Ph2, Ph3) and earth (T) are open circuit. The spark gaps include at least two branches mounted in parallel, each having a spark gap (E1, E2) in series with an inductance (l1, l2). The device also has thermal disconnecters, e.g. fuses (DTE1, DTE2), which are sensitive to the state of the arc gaps and are individually associated with each spark gap.
Patent DE-69836098-T3 (DE)
Inventor: BECKER NATHANIEL
IPC: C12N9/98
Filed: 1998-12-18
Granted: 2014-04-30
Abstract: Granules that include a protein core are described. The protein core includes a protein matrix which includes a protein mixed together with a combination of a sugar or sugar alcohol and a structuring agent such as a polysaccharide or a polypeptide. The protein matrix can be layered over a seed particle or the protein granule can be homogeneous. The protein can be an enzyme or a therapeutic protein such as a hormone. Also described are methods for making the granules.
Patent DK-1094595-T3 (DK)
Inventor: ACQUAVIVA SEBASTIANO
IPC: H02P6/06
Filed: 2000-10-20
Granted: 2010-05-31
Abstract: The device (10) comprises   two supply terminals (11, 12) intended to be connected to an alternating supply source, a switching circuit (13) connected to an end terminal (B) and to the intermediate tapping (C) of the stator winding (5) and operable to assume a first and then a second condition in which it allows coupling to the voltage source of a the first portion (L1) of the stator winding (5) and the entire winding (5) respectively; a timer circuit (14) coupled to the switching circuit (13) and operable to cause it to pass from the first to the second condition after a reference time period of application of voltage to the supply terminals (11, 12,) and a synchronisation circuit (15) coupled to a rotor position sensor (16) and arranged to control the current at least in the first portion (L1) of the stator winding (5) in a predetermined manner in dependence on the polarity on the voltage delivered from the source and the position of the rotor (2) in order to cause in the starting phase of the motor (1), the rotor (2) to rotate at an increasing speed until reaching, in a time less than or equal to the said reference time period, a synchronisation speed corresponding to the frequency of the alternating supply voltage.   <IMAGE>
Patent DK-1092437-T3 (DK)
Inventor: BURET ANDRE G
IPC: A23K1/16
Filed: 1996-05-09
Granted: 2005-01-31
Abstract: A new use of epidermal growth factor (EGF) for preparing an agent for increasing weight gain in an animal is described. The agent is preferably formulated as a food additive or drinking water additive and administered in the feed of the animal. Another use of EGF is for preparing a medicament for treating malnourished people and persons suffering from anorexia nervosa. As such EGF can be used to increase animal production, for example in the agriculture or aquaculture industry.
Patent DK-1187603-T3 (DK)
Inventor: NAJARIAN THOMAS
IPC: A61K31/535
Filed: 2000-06-14
Granted: 2007-12-17
Abstract: The present invention features a novel therapy for effecting weight loss which involves treating a subject with a sympathomimetic agent (e.g. phentermine or a phentermine-like drug) in combination with an anticonvulsant sulfamate derivative (e.g., topiramate) such that the subject experiences weight loss. The combination methods of the present invention also are effective against symptoms associates with Syndrome X. The invention also features pharmaceutical compositions and kits for use in the practice of these novel therapies.
Patent DK-1196566-T3 (DK)
Inventor: CHISHOLM VANESSA
IPC: C07K16/42
Filed: 2000-07-11
Granted: 2006-06-06
Abstract: Vectors and methods for efficient isolation of recombinant cells expressing high levels of a desired protein are provided. The vectors comprise an amplifiable selectable gene, a fluorescent protein gene, and a gene encoding a desired product in a manner that optimizes transcriptional and translational linkage.
Patent DK-1232282-T3 (DK)
Inventor: COLINGE JACQUES
IPC: C12Q1/68
Filed: 2000-11-16
Granted: 2005-05-23
Abstract: The invention relates to an automated method for identifying related biomolecular sequences having defined features of interest from databases, the databases comprising at least a first and a second set of sequences, each set being derived from a different type of organism, comprising the steps of:   a) establishing from the first set of sequences a non-redundant list of query sequences having the defined features of interest (first family members), using a database search program; b) performing sequence alignments with the first family members in a second set of sequences derived from a second type of organism, using a database search program and a preset similarity threshold, giving a list of second family members; c) establishing a two dimensional matrix displaying the first and second family members and their respective similarity values resulting from step (b), optionally displaying only those second family members having similarity values exceeding a preset threshold value; d) selecting from the matrix those pairs of first and second family members for which the similarity values are the best among all of the alignments that involve one of the two pair's members (orthologs).
Patent DK-1155614-T3 (DK)
Inventor: MCCALLUM WILLIAM GORDON
IPC: A01M1/10
Filed: 2001-05-17
Granted: 2006-05-29
Abstract: An insect trap fitting adapted to cover an opening in a receptacle containing insect attractant. The fitting includes a cover plate with a first aperture in it and a first skirt extending downwardly from the periphery of the first aperture. A screen with a second aperture in it is located at the lower edge of the first skirt. A blade extends from the second aperture to a position above the first aperture in the cover plate. The fitting my also include a second skirt extending downwardly from the periphery of the second aperture, the blade extending from the lower edge of the second skirt to above the level of the first aperture in the cover plate. A fly trap includes the fitting and a receptacle. <IMAGE>
Patent DK-1290006-T3 (DK)
Inventor: MARLIERE PHILIPPE
IPC: C07H19/06
Filed: 2001-06-13
Granted: 2007-06-18
Abstract: Hydrazide-substituted nucleoside or nucleotide analogs (I) are new. Nucleoside or nucleotide analogs of formula (I) are new. [Image] R 1H; mono-, di- or tri-phosphate group; or protective group such as DMT; R 2, R' 2H, OH, phosphoramidite (or derivative), H-phosphonate or chain terminator T; R 3, R' 3H, OH, halo, 1-6C alkyl or OR 5; R 51-6C alkyl; R 45-membered heterocycle of formula (a) (e.g. pyrrole, pyrazole, imidazole, 1,2,4-triazole or tetrazole), 6-membered heterocycle (preferably of formula (b)) or purine analog of formula (c), (a)-(c) being bonded to the sugar residue at N and to E at C; E : optionally substituted, saturated or unsaturated spacer arm comprising 0-20C and optionally heteroatoms; X : CH, CR 6, or N; R 6halo, 1-6C alkyl, OR 7or SR 7; R 71-6C alkyl; Y 1NH 2, N=C(Z 1)(Z 2) or NH-CHZ 1Z 2; Y 2, Y 3H, OH, O, NH 2, halo, amine, amido or 1-6C alkyl; Z 1, Z 2H or organic group. [Editor's note: DMT is not defined in the specification.] Independent claims are included for: (i) the preparation of (I); (ii) libraries of compounds (I); (iii) nucleic acids (II) containing at least one compound (I). (iv) a method for identifying compounds capable of introducing a mutation into a nucleic acid, by incorporating (I; Y = NH 2) in a synthetic oligonucleotide, reacting with an aldehyde or ketone (or a library of aldehydes and/or ketones) optionally followed by reduction, replicating the oligonucleotide using a polymerase (specifically an exo-DNA polymerase) and determining whether a mutation has been introduced into the newly synthesized strand; (v) a method for point mutation of a nucleic acid, by preparing a synthetic oligonucleotide containing at least one compound (I) and replicating as in (iv); (vi) a method for random mutation of a nucleic acid involving using a reaction mixture containing at least one compound (I) for the amplification of a nucleic acid; (vii) a method for identifying a compound capable of inhibiting a polymerase (specifically a reverse transcriptase or kinase), by testing the activity of the enzyme in presence of at least one compound (I); (viii) a method for identifying a compound capable of inhibiting viral reverse transcriptase, by testing the effect of at least one compound (I) (in the form of a nucleoside analog) on infected cells; and (ix) a kit for the amplification and/or detection of a target nucleic acid, containing (I) or (II). ACTIVITY : Virucide; cytostatic. MECHANISM OF ACTION : Polymerase inhibitor; reverse transcriptase inhibitor; nucleotide kinase inhibitor; antisense nucleic acid.
Patent DK-1328374-T3 (DK)
Inventor: BELLONI ANTONIO
IPC: B23K9/00
Filed: 2001-10-22
Granted: 2007-04-10
Abstract: A method of laying a pipeline ( 6 ) underwater includes the steps of holding an end of a pipeline ( 6 ), providing a pipe section ( 5 ) for extending the pipeline ( 6 ), arranging the pipe section ( 5 ) adjacent to the end of pipeline ( 6 ) thereby defining a circumferential joint ( 7 ) to be welded, and welding the pipes ( 5, 6 ) together. A plurality of welding torches ( 8 ) move along the circumferential joint ( 7 ) and are operated simultaneously to weld the pipes together. The pipes ( 5, 6 ) are made of TMCP-SC steel. After the root weld is laid, a cooling ring ( 1 ) mounted on an internal clamp inside the pipes ( 5, 6 ) sprays cooling liquid, for example a fluid spray of atomised water ( 10 ) and air, from nozzles ( 2 ) onto an interior surface of the pipes ( 5, 6 ) in the region of the circumferential joint ( 7 ), thereby cooling the pipes ( 5, 6 ).
Patent DK-1204209-T3 (DK)
Inventor: CALDWELL DAVID W
IPC: H03K17/96
Filed: 1995-10-25
Granted: 2005-01-24
Abstract: Each of a plurality of touch pads for detecting manual contact by a human user and capable of activating a control device comprises a dielectric substrate (10) of substantially uniform thickness. A first thin conductive electrode pad (16) is disposed on a first surface of the substrate in a closed, continuous geometric form having an area which affords substantial coverage by a human appendage. A second thin, conductive electrode (18) is also disposed on the first surface of the substrate (10) and surrounds, but is spaced from, the first conductive electrode (16) on peripheral edges having an adjacent touch pad. <IMAGE>
Patent DK-1221322-T3 (DK)
Inventor: WALKER CLARENCE LOGAN
IPC: A61M39/16
Filed: 1995-04-17
Granted: 2005-12-19
Abstract: The present invention relates to a stop-cock valve (10) useable in conjunction with a fluid delivery set for delivering fluids such as intravenous fluids or enteral fluids from one or more containers to a patient. The valve (10) comprises a rotatable stem (13) which includes a V-shaped fluid flow passage (21) comprising a first arm (22) and a second arm (23) which have a convergence at (24).