baber/WOPTO huggingface dataset:
Patent EP-3990662-A1 (EP)
Title: Method for determining the presence or absence of minimal residual disease (mrd) in a subject who has been treated for a disease
Inventor: BARRIO GARCÍA SANTIAGO
IPC: G16B30/10
Filed: 2020-08-27
Abstract: The present invention is focused on a method, kit and system for determining the presence or absence of minimal residual disease in a subject who has been treated for a proliferative disease wherein said method, kit and system comprise: (A) amplifying and sequencing at least one nucleotide sequence comprised in genomic DNA from a biological sample obtained from said subject prior to treatment for said disease, to obtain a first list of characters reading from left to right; (B) amplifying and sequencing at least one nucleotide sequence comprised in genomic DNA from a biological sample obtained from said subject after treatment for said disease, to obtain a second list of characters reading from left to right, wherein when a nucleotide sequence is mutated it is a genetic marker for said proliferative disease; (C) determining, for each second list of characters obtained in step (B), the degree of similarity, DS, with each first list of characters obtained in step (A); (D) selecting, for each second list of characters obtained in step (B), the DS of highest value, DS HV ; (E) adding up the number of second lists of characters which have a DS HV  that is greater than a threshold value, T, to obtain L c , (F) adding up the total number of second lists of characters, L t ; (G) calculating the level of minimal residual disease, MRD, according to any of the following formulae: MRD = (L c  x k) / (L t  x D) or MRD = L c  / L t  or MRD = g x L c  x (D / k) / L t 
 2 ; (H) determining (i) the minimum variant read frequency, minVRF, of said genetic marker, (ii) the limit ofdetection, D-limit, of said genetic marker (iii) the average mutation noise, avMut and (iv) the average position noise, avPos; (I) determining the experimental sensitivity, ES, from the greater of the minVRF, D-limit, avMut and avPos or from the greater of minVRF and D-limit; (J) determining the presence or absence of minimal residual disease in said subject by comparing the value of the level of minimal residual disease with the value of ES, the values of minVRF, D-limit, avMut and avPos, or the values of minVRF and D-limit; wherein when said level of minimal residual disease is equal to or greater than said ES, minVRF, D-limit, avMut or avPos values, minimal residual disease is present in said subject.
Patent EP-4030921-A1 (EP)
Inventor: BARONE GIOVANNI
IPC: A23C21/06
Filed: 2020-09-15
Abstract: The invention concerns whey-based nutritional compositions fortified with calcium that are suitable for infant nutrition, including infant formula (IF) and growing up milk (GUM). The nutritional compositions are based on α-lactalbumin enriched whey protein concentrate that has been fortified with calcium.
Patent EP-3943182-A1 (EP)
Inventor: UWATOKO Miku
IPC: B01J20/281
Filed: 2020-03-13
Abstract: The present invention relates to a polymer including at least one structure selected from the group consisting of a structure represented by General Formula (3) described below and a structure represented by General Formula (4) described below:
     
in General Formula (3) and General Formula (4) described above, X 31  and X 41  represent a hydrophilic group-containing structure, n represents an integer of 0 to 2, R represents a hydrogen atom or an alkyl group, Y 31  to Y 32  and Y 41  to Y 43  each independently represent a hydrophilic group-containing structure, a hydrogen atom, or an alkyl group.
Patent EP-4038291-A1 (EP)
Inventor: HIDRINGER MICHAEL
IPC: F16D65/18
Filed: 2020-10-01
Abstract: A brake plunger (1) of a disk brake of a utility vehicle has an actuating spindle (6), with a threaded tube (61) and with an actuating spindle head (62) which projects out of an end surface (66) of the threaded tube (61), and has a thrust piece (7), which is seated on the actuating spindle head (62) so as to be secured axially in relation to a longitudinal axis of the actuating spindle (6) and which has a receiving opening (72) for receiving the actuating spindle head (62), wherein a sliding sleeve (9) is arranged between the thrust piece (7) and the actuating spindle head (62), wherein the sliding sleeve (9) or the thrust piece (7) is secured axially in a groove (64, 68) of the actuating spindle (6). Also described is a disk brake of a utility vehicle having at least one such brake plunger (1).
Patent EP-3956016-A1 (EP)
Inventor: LONG CHRISTOPHER JOSEPH
IPC: A61N1/372
Filed: 2020-04-09
Abstract: Un implant cochléaire apical comprend un ensemble électrode apicale en association avec un ensemble électrode basilaire. L'implant cochléaire apical est conçu pour stimuler la cochlée d'un receveur par l'intermédiaire de l'ensemble électrode apicale en association avec l'ensemble électrode basilaire.
Patent EP-4044840-A1 (EP)
Title: Aerosol delivery device with dual reservoir
Inventor: HEJAZI VAHID
IPC: A24F40/30
Filed: 2020-10-15
Abstract: The present disclosure provides an aerosol delivery device that comprises a housing defining an outer wall, and further including a power source and a control component, a mouthpiece portion that defines an aerosol exit path, a first reservoir configured to contain a first liquid composition, a second reservoir configured to contain a second liquid composition, a first atomization assembly configured to vaporize the first liquid composition to generate a first aerosol having a first aerosol particle size, and a second atomization assembly configured to vaporize the second liquid composition to generate a second aerosol having a second aerosol particle size. The first liquid composition may be different than the second liquid composition, and the first particle size may be different than the second particle size.
Patent EP-4052007-A1 (EP)
Inventor: WAGNER-STÜRZ DAVID
IPC: G01M13/003
Filed: 2020-10-30
Abstract: Vorgeschlagen wird ein Verfahren zum Festlegen von Abbruchkriterien für einen Teilhubtest an einem Sicherheitsventil, mit folgenden Schritten: a) Ein Teilhubtest wird zu einem Zeitpunkt, an dem das Sicherheitsventil funktionsfähig ist, durchgeführt. b) Die Stellung des Ventilglieds und der Druck im Antriebsfluid werden aufgezeichnet. c) Daraus wird eine erste Relation abgeleitet, die die Stellung des Ventilglieds und/oder die Zeit und/oder den Druck des Antriebsfluids und/o-der die Regelabweichung zueinander in Beziehung setzt. d) Diese Relation wird als Referenz-kurve für dieses Sicherheitsventil definiert. e) Eine zweite Relation wird definiert, die einen vor-gegebenen Abstand zur Referenzkurve aufweist. f) Als Abbruchkriterium wird festgelegt: Wird der Teilhubtest an demselben Ventil wiederholt, dabei die gleichen Daten aufgezeichnet, und aus den Daten wie bei der Referenzkurve eine dritte Relation abgeleitet, so ist der Teilhubtest nicht bestanden, wenn die dritte Relation einen größeren Abstand zur Referenzkurve hat als die zweite Relation.
Patent EP-3972584-A1 (EP)
Inventor: DOCHERTY JOHN
IPC: A61K31/352
Filed: 2020-05-19
Abstract: Disclosed herein are nanoemulsions, the nanoemulsions comprising biologically active ingredients. Further disclosed are processes for preparing the nanoemulsions and methods of their use.
Patent EP-4061670-A1 (EP)
Title: Schlosseinheit mit kopplungsmechanismus für einen integrierten leerhub
Inventor: KRÜGER FRIEDER
IPC: B60N2/36
Filed: 2020-11-19
Abstract: Die vorgeschlagene Lösung betrifft eine Schlosseinheit für ein Fahrzeug, mit - einem Träger (1), - einem an dem Träger (1) zwischen einer Verriegelungsposition und einer Freigabeposition schwenkbaren Verriegelungselement (2), - einem an dem Träger (1) zwischen einer Sperrposition und einer Entriegelungsposition schwenkbaren Sperrelement (3), das in seiner Sperrposition das in der Verriegelungsposition vorliegende Verriegelungselement (2) gegen eine Verstellung in die Freigabeposition sperrt und in seiner Entriegelungsposition eine Verstellung des Verriegelungselements (2) aus der Verriegelungsposition in seine Freigabeposition gestattet, und - einem an dem Träger (1) innerhalb eines Verstellbereichs verstellbaren Betätigungselement (6) zum Schwenken des Sperrelements (3) aus der Sperrposition in Richtung der Entriegelungsposition. Das Betätigungselement (6) ist über einen Kopplungsmechanismus (K) mit dem Sperrelement (3) gekoppelt, über den eine Verstellbewegung des Betätigungselements (6) lediglich in einem Teilbereich des Verstellbereichs des Betätigungselements (6) in eine Schwenkbewegung des Sperrelements (3) in Richtung seiner Entriegelungsposition umsetzbar ist.
Patent EP-4062198-A1 (EP)
Title: Satellite-based tracking of metallurgical vessels in a metal industrial plant
Inventor: BRAAM MALTE
IPC: G05B19/418
Filed: 2020-11-23
Abstract: System (1) and method for tracking at least one transport means (10) in a metal industrial plant. The system (1) also has at least one receiving unit (20) which is configured to receive position data from the transport means (10), wherein the transport means (10) has an electronic assembly comprising: a receiving device (11) which is configured to receive radio codes from satellites (2) of a navigation satellite system; a data processing device (13) which is configured to provide position data from the radio codes from the satellites (2); and a transmitting device (12) which is configured to transmit the position data to the receiving unit (20).
Patent EP-3989327-A1 (EP)
Inventor: KURISAWA ISAMU
IPC: H01M10/42
Filed: 2020-06-17
Abstract: A determination method includes determining whether or not measurement data relating to a plurality of energy storage devices included in a system is periodically stored in a storage device, determining whether or not each of the energy storage devices reaches end of its life within a period corresponding to a standard use period at a predetermined temperature based on acquired measurement data in a case where measurement data is determined to be stored, and determining that replacement is necessary for an energy storage device that is determined to reach end of its life.
Patent EP-4069231-A1 (EP)
Title: Methods for treating behavioral and psychological symptoms in patients with dementia
Inventor: NIROGI RAMAKRISHNA
IPC: A61K31/496
Filed: 2020-12-02
Abstract: The present invention provides a method for treating behavioral and psychological symptoms in patients with dementia comprising administering an effective dose of pure 5-HT 6  receptor antagonist and acetylcholinesterase inhibitor or NMDA receptor antagonist. The present invention also relates to a pharmaceutical combination comprising pure 5-HT 6  receptor antagonist and acetylcholinesterase inhibitor or NMDA receptor antagonist, in particular for treating behavioral and psychological symptoms in patients with dementia. The present invention further provides use of the said compounds in the manufacture of a medicament, and a pharmaceutical composition comprising the said compounds intended for the treatment of disorders described herein.
Patent EP-4007447-A1 (EP)
Inventor: LEE CHUNGJAE
IPC: H05K9/00
Filed: 2020-07-10
Abstract: A film type planar heating element for preventing electromagnetic waves is configured in a form of multiple layers of films to generate heat, the film type planar heating element comprising: a base film made of synthetic resin and mounted on a floor in a form of sheet film; a carbon heating unit made of carbon materials and arranged in multiple rows to generate heat planarly on a top side of the base film; a pair of center-adjacent copper foil busbars disposed in a center area of the base film, applying current to the carbon heating unit, and facing each other in a close distance so that intensities of electromagnetic waves and magnetic field are mutually canceled each other when the current is applied; a pair of center silver busbars formed between the carbon heating unit and the center-adjacent copper foil busbars and made of silver materials allowing the current, which is applied to the center-adjacent copper foil busbars, to smoothly flow to the carbon heating unit, and a Lamirex film coated on the top side of the base film to protect the carbon heating unit and the center-adjacent copper foil busbars.
Patent EP-4004642-A1 (EP)
Inventor: RICHLICH STEPHEN F
IPC: G02F1/155
Filed: 2020-07-24
Abstract: An electro-optic element includes first and second spaced-apart transparent substrates defining respective opposite, aligned first and second edges, a first bus including a first electrode disposed along an inner surface of the first substrate adjacent the first edge and a second electrode disposed along an inner surface of the second substrate adjacent the first edge, and a second bus including a first electrode disposed along an inner surface of the first substrate adjacent the second edge and a second electrode disposed along an inner surface of the second substrate adjacent the second edge. The first bus and second bus are spaced apart along widths of the first and second substrates between the respective first and second edges. An electro-optic medium is disposed between the first and second transparent substrates, including between the first and second electrodes of the first bus and the second bus, respectively.
Patent EP-4025920-A1 (EP)
Inventor: HAMILTON DOUGLAS
IPC: G01R19/25
Filed: 2020-09-03
Abstract: L'invention concerne un capteur de ligne électrique qui comprend un boîtier et un capteur en champ proche. Le boîtier est conçu pour être couplé à une ligne électrique. Le capteur en champ proche est configuré pour détecter un courant de fuite sur la ligne électrique.
Patent EP-4033685-A1 (EP)
Title: Resource determination method and apparatus
Inventor: GAO XUEJUAN
IPC: H04L5/00
Filed: 2020-08-11
Abstract: Disclosed are a resource determination method and apparatus for flexible acquisition of a PUCCH resource by a terminal at each sub-slot or each TRP. At a terminal side, a resource determination method provided in the present disclosure comprises: receiving configuration signaling, and acquiring at least one physical uplink control channel (PUCCH) resource set on the basis of the configuration signaling; determining a target PUCCH resource set; and according to a PUCCH resource indication domain and the serial number of a target corresponding to the PUCCH, determining a PUCCH resource from the target PUCCH resource set, wherein the target comprises a sub-slot where PUCCH transmission is located and/or a transmission receiving point (TRP) corresponding to the PUCCH.
Patent EP-4034307-A1 (EP)
Inventor: IVANYTSKYY OLEG
IPC: B06B1/06
Filed: 2020-09-23
Abstract: A hydrophone used for measuring acoustic energy from a high frequency ultrasound transducer, or a method of manufacturing the membrane hydrophone. The membrane assembly is supported by the frame and comprises a piezoelectric. The hydrophone also includes an electrode pattern formed within the piezoelectric to define an active area. In addition, the hydrophone includes a built in-situ coaxial layer connected to the active area.
Patent EP-4035924-A1 (EP)
Inventor: KONO TSUTOMU
IPC: H01H33/662
Filed: 2020-08-31
Abstract: The present invention provides a railroad vehicle switch that realizes a weight reduction from the viewpoint of a restriction on load carrying capacity, and a method for manufacturing the same. In order to solve the above problem, a railroad vehicle switch includes a vacuum interrupter including a fixed electrode and a movable electrode that comes into contact with or separates from the fixed electrode; a fixed conductor connected to the fixed electrode; a first bushing conductor electrically connected to the fixed conductor; a movable conductor connected to the movable electrode; a second bushing conductor electrically connected to the movable conductor; an air insulation operating rod disposed coaxially with the movable conductor; a solid insulating member being made of a thermosetting resin and covering the vacuum interrupter and the first and second bushing conductors; and a structure member being made of a thermoplastic resin and being joined to a portion of the solid insulating member forming an air insulation space in a peripheral portion of the air insulation operating rod. A part of the air insulation space is formed in a space formed by the solid insulating member made of the thermosetting resin and the structure member made of the thermoplastic resin.
Patent EP-4034293-A1 (EP)
Inventor: BISHOP BENJAMIN ISAIAH
IPC: C12M1/00
Filed: 2020-09-25
Abstract: An agitator device for mixing materials, including a containment vessel defining an interior volume, a hollow shaft having an upper end, a lower end, and a central bore along its length, the lower end extending downwardly into the interior volume of the containment vessel, the hollow shaft being rotatable with respect to the containment vessel, and a takeout tube having an upper end and a lower end, wherein the takeout tube is disposed within the central bore of the hollow shaft so that the lower end of the takeout tube is in fluid communication with the interior volume of the containment vessel.
Patent EP-4045720-A1 (EP)
Inventor: AUGHTON DAVID JOHN
IPC: E02B7/44
Filed: 2020-10-15
Abstract: Grille de commande pour un canal ou un étang qui est conçue pour être installée à travers un canal pour des liquides. Ladite grille de commande comprend : au moins deux panneaux reliés de manière articulée l'un à l'autre, les panneaux ayant des côtés opposés en prise étanche avec les parois latérales du canal, le panneau inférieur étant en prise étanche avec le fond du canal et les panneaux étant sensiblement alignés verticalement dans une position complètement fermée de la grille de commande ; au moins un premier moyen de levage relié à la partie supérieure du panneau supérieur conçu pour abaisser et élever le panneau supérieur par rapport à sa liaison articulée en accordéon pour fournir une position de dépassement pour la grille de commande ; au moins un second moyen de levage relié au fond du panneau inférieur pour soulever et abaisser le panneau inférieur à partir du fond du canal pour fournir une position de repêchage pour la grille de commande.
Patent EP-3876768-A1 (EP)
Inventor: CHO BYUNG SUNG
IPC: A24F40/10
Filed: 2020-12-14
Abstract: An aerosol generating device and a controlling method thereof are provided. An aerosol generating device includes: a battery configured to supply power for generating an aerosol from an aerosol generating material; a converter configured to convert a supply voltage from the battery into a constant voltage of a predetermined level; a heater configured to heat the aerosol generating material using the supply voltage; a detection circuit configured to detect a change in resistance of the heater by applying the constant voltage output from the converter and performing a current sensing on the heater with a resistance value; and a controller configured to control the heater for generating the aerosol by switching between a monitoring mode for performing the detection of the change in the resistance of the heater using the constant voltage and a heating mode for heating the heater using the supply voltage.
Patent EP-4055660-A1 (EP)
Title: Étiquette rfid
Inventor: HUHTASALO LAURI
IPC: H01Q1/22
Filed: 2020-11-04
Abstract: La présente invention concerne une étiquette RFID (1) qui comporte un marqueur RFID (V7) qui comprend une antenne RFID (5) et un circuit intégré CI (6), lequel CI est fixé sur l'antenne de façon que l'antenne et le CI forment le marqueur RFID. L'étiquette de l'invention comprend en outre un substrat allongé (2) avec une première surface (3) et une seconde surface (4), la première surface étant siliconée, et la seconde surface portant le marqueur RFID (7), et une couche adhésive collante (8) qui est disposée sur la seconde surface du substrat et sur le marqueur RFID.
Patent EP-4059684-A1 (EP)
Inventor: TANAKA TADAHARU
IPC: B29K101/12
Filed: 2020-11-05
Abstract: A resin-integrated fiber sheet 1 for vacuum forming for producing a fiber reinforced resin molded body through vacuum forming includes: unidirectional continuous fibers 2 that are spread fibers of a continuous fiber group and arrayed in parallel in one direction; bridging fibers 3 lying in directions crossing the unidirectional continuous fibers 2; and thermoplastic resin 4 present on part of the surface of the unidirectional continuous fibers 2 to unify the unidirectional continuous fibers 2 and the bridging fibers 3. A fiber reinforced resin molded body of the present invention is a vacuum formed body in which two or more of the resin-integrated fiber sheets 1 are stacked. A method for producing the molded body of the present invention includes subjecting the resin-integrated fiber sheets 1 to vacuum forming from a lower mold with a vacuum line and pressurizing the sheets with compressed air from an upper mold. Thus, the present invention provides a resin-integrated fiber sheet for vacuum forming having excellent shapeability and avoiding voids, a molded body including the same, and a method for producing the molded body including the same.
Patent EP-4059330-A1 (EP)
Inventor: LAVIGNE PATRICK EUGENE
IPC: A01B23/06
Filed: 2020-11-06
Abstract: This invention relates to an agricultural disc (1) for use in agricultural work, such as to open furrows in the soil for sowing or to prepare the land for tillage and grinding, comprising two surfaces (8, 9), a cutting circular perimeter edge (11) and a plurality of notches (2) located on a first surface (9) of said agricultural disc (1), distributed in a circular matrix shape concentric to the agricultural disc (1), located adjacent to the perimeter edge (11). The invention also comprises the process for manufacturing the agricultural disc (1) comprising a step of creating a plurality of undulations (4) in a circular disc (20) and a step of shaving or straightening via machining the crests generated on a second surface (8) when the undulations (4) are generated.
Patent EP-4065318-A1 (EP)
Inventor: KARLSSON FREDRIK
IPC: A01G3/053
Filed: 2020-11-25
Abstract: A hand-held electrically powered cut-off tool (100, 200, 800, 1000, 1900) comprising a first part (110) and a second part (120) arranged vibrationally isolated from each other, the first part (110) comprising an arm (116) arranged to support a cutting disc (130) and an electric motor (140) arranged to drive the cutting disc, the second part (120) comprising front (190) and rear (195) handles for operating the cut-off tool, and a battery compartment (150) for holding an electrical storage device (220, 1800) such as a battery arranged to power the electric motor (140), wherein one or more damping members (170, 1910) are arranged in-between the first part (110) and the second part (120), where at least one damping member (170, 1910) is formed in a resilient material associated with a damping coefficient.
Patent EP-3974458-A1 (EP)
Inventor: SHIN MIN SEUNG
IPC: C08F222/08
Filed: 2020-11-25
Abstract: Provided is a method of preparing a maleimide-based copolymer, which comprises adding a monomer mixture including an aromatic vinyl-based monomer and a maleimide-based monomer to an aqueous solution consisting of an aqueous solvent and a first vinyl cyanide-based monomer and performing polymerization.