Patent RU-2547791-C9 (RU)
Inventor: IZILOV JAKOV JUNOEVICH
IPC: A61K31/66
Filed: 2013-12-12
Granted: 2015-06-27
Abstract: FIELD: medicine. 
     SUBSTANCE: patient receives a therapeutic diet favouring the weight loss and providing the sufficient intake of alimentary calcium and vitamins: C, D, E, K simultaneously with orthopaedic unloading. The patient also receives the drug Fosamax® per os in the form of tables in the dose of 70 mg once a week for 6 months, the drug Artrodarin® per os in the form of capsules in the dose of 50 mg in the morning and in the evening for 4-6 months and the drug Miacalcic® intranasally in the dose of 200 IU per day in 2-week cycles with an interval of 2 weeks for 4-6 months. Besides that, the drug Milgamma® is administered in the form of solution for intramuscular injections in the dose of 2 ml daily not less than 10 times with an interval of 1 day. The drug Alflutop® is injected intramuscularly in the dose of 2 ml per day every day for not less than 20 days. Additionally, the patient receives a course of treatment which includes 8-10 therapeutic sessions each of them comprising two consecutive stages of procedures. The first of these stages includes abdominal decompression with the influence on the region below the waist on the whole inferior part of the body, pneumocompression massage with the impact on the legs, manual and vacuum massage performed consecutively during one day. The exposed regions: hip joints - lateral surface of the thighs, gluteal region and L2-L5 paravertebral zones, C7-T1 cervical paravertebral zone and sacrum. The preferable interval between the above procedures is not more than 10-15 minutes. After that, the first stage of the therapeutic session is completed by hirudotherapy using not more than 8 medical leeches per one session, which are applied on the C7-T1 cervical paravertebral zone and L2-L5 lumbar paravertebral zone, sacrum, coccyx, on the abdomen in the region of the liver, inferior part of the abdomen, painful hip regions and/or regions which changed their colour after massage. Then each therapeutic session is completed by consecutive performing the procedures of the second stage after an interval of not less than 3 days. Magnet therapy and laser barotherapy are performed by the exposure of the regions: hip joints - lateral surface of the thighs, gluteal region and L2-L5 paravertebral zones. Phonophoresis using Caripain gel is performed by the exposure of the gluteal, knee and hip regions. After that, an interval of 24 hours is made and the therapeutic session is repeated not more than 10 times depending on the patient's condition. Then the patient performs therapeutic physical exercises in a swimming pool for not less than 10 days. Simultaneously, the peptide drug Kartalaks® is administered intramuscularly in the dose of 1-2 ml of the solution with concentration of not less than 100 mcg/1 ml diluted with 10 mg of the drug Thymalin® once a day for 10 days. After completing the course of these injections, the patient receives the peptide drug Vesugen® per os in the form of capsules in the dose of 0.2 g and the drug Kartalaks® in the form of capsules in the dose of 0.2 g daily in the morning and in the evening 10-15 minutes before meals. After completing the continuous single course of the drug Fosamax® and nasal spray of the drug Miacalcic®, an interval of 1-2 months is made and then the patient receives daily the drug Osteogenon® per os in the form of 830 mg tablets in the dose of 2-4 tablets twice a day and the drug Artrodarin® in the form of capsules in the dose of 50 mg in the morning and in the evening for 4-6 months. The peroral administration of the latter two drugs is repeated with an interval of not less than 3 months. 
     EFFECT: preventing the resorption and loss of the bone tissue, recovering the shape, volume and normal consistency of the intraarticular cartilage; these effects allow to avoid the further progression of the disease and performing a surgery in this patient category. 
     3 cl, 3 ex