baber/WOPTO huggingface dataset:
Patent NZ-555601-A (NZ)
Title: Anti-integrin immunoconjugates, methods and uses
Inventor: CHEN QIMING
Filed: 2005-11-30
Abstract: Disclosed is an antibody conjugate of formula m wherein the antibody is a human alphaV integrin subunit specific antibody, wherein said antibody is capable of being internalized by the cell expressing said alphaV subunit; wherein the maytansinol is esterified at C-3; R1, R2, X1 and X2 are independently H, Me, C2H5 linear alkyl or alkenyl having from 1 to 10 carbon atoms branched or cyclic alkyl or alkenyl having from3 to 10 carbon atoms, phenyl, substituted phenyl, or a heterocyclic aryl moiety, or a heterocycloalkyl moiety; n is 1-5; p is 1-5; and m is 1 to 10, and the pharmaceutically acceptable salts and esters thereof.
Patent NZ-565247-A (NZ)
Title: Process for the production drospirenone utilising the metal-free oxidation of 17-(3-hydroxypropyl)-3,17-dihydroxyandrostanes with TEMPO
Inventor: SEBA HARTMUT
IPC: C07J19/00
Filed: 2006-07-20
Abstract: Disclosed is a process for the production of a 3-oxo-pregnane-21,17-carbolactone of formula II, comprising the reaction of a compound of formula I, with at least 3 molar equivalents of an organic or inorganic hypochlorite as oxidizing agent in the presence of catalytic amounts of a 2,2,6,6-tetramethylpiperidine-N-oxide derivative (TEMPO) at a pH of at least 8.0, wherein R5 is hydrogen or hydroxy; R6a is hydrogen, or together with R7a a -CH2 group; R6b is hydrogen, or together with R7b a -CH2 group or a double bond; R7a is hydrogen, alkyl, alkoxycarbonyl, thioacyl or together with R6a a -CH2 group, R7b is hydrogen, or together with R6b a -CH2 group or a double bond; R9 is hydrogen or together with R11 is a double bond, or together with R11 is an epoxy group -O-; R10 is hydrogen, methyl, or ethyl; R11 is hydrogen, or together with R9 a double bond or together with R9 is an epoxy group -O-; R13 is hydrogen, methyl or ethyl; R15 is hydrogen, alkyl, or together with R16 a -CH2 group or a double bond; R16 is hydrogen, or together with R15 a -CH2 group or a double bond. Also disclosed is a process for the production of a 3-oxo-pregn-4-ene-21,17-carbolactone of formula III which comprises the elimination of water from a compound of formula II at a pH of less than 5, optionally in the presence of an acid. Further disclosed is the use and preparation of 6b,7b;15b,16b-dimethylene-3-oxo-17a-pregnan-5b-ol-21,17-carbolactone-dichloromethane hemisolvate of formula (IV).
Patent NZ-568396-A (NZ)
Title: Variable ignition delay for combustion nailer
Inventor: MOELLER LARRY M
IPC: B25C1/08
Filed: 2006-11-17
Abstract: A combustion-powered fastener-driving tool comprises tool housing, a power source 14 associated with the housing and including a cylinder head 42, a cylinder 20 and a piston 22 reciprocating in the cylinder 20, a valve sleeve 36 reciprocating relative to the cylinder 20, a chamber switch 44 and a trigger switch. The cylinder head 42, the cylinder 20, the valve sleeve 36 and the piston 22 combine to define a combustion chamber. A fan 48 is disposed in the combustion chamber. To initiate ignition of the power source 14 to drive the piston 22 down the cylinder 20 both switches have to be closed. A control system including a control program associated with the housing is connected to the power source 14, the chamber switch 44 and the trigger switch. The control system is configured to provide a designated ignition delay period when the chamber switch 44 is closed. The delay period is variable, and is a function of monitored tool parameters.
Patent NZ-575183-A (NZ)
Title: Ibuprofen-effervescent preparation having a high dissolution rate and method for the production thereof
Inventor: GRUBER PETER
IPC: A61K31/19
Filed: 2007-08-30
Abstract: Disclosed is an effervescent ibuprofen formulation comprising (a) an active ingredient-containing granule which comprises ibuprofen and a basic excipient, and (b) an effervescent granule which comprises an acid component e.g. malic, ascorbic or citric acid and a carbon dioxide-forming component e.g., hydrogen carbonate salts wherein the active ingredient-containing granule comprises the ibuprofen in the form of a water-soluble salt, and wherein the formulation is produced by a process in which the active ingredient-containing granule is prepared by intensively mixing ibuprofen in the form of its free acid with one or more basic excipients without adding water.
Patent NZ-580533-A (NZ)
Title: Cell lines, compositions comprising them for the treatment of melanomas, procedures to prepare the compositions, and treatment methods
Inventor: MORDOH JOSE
IPC: A61K39/00
Filed: 2008-04-11
Abstract: A composition of human melanoma cells lines that can be used for treatment of melanoma. The composition comprises the cell lines Mel-XY1 (DSM ACC2830), Mel-XY2 (DSM ACC2831) and Mel-XY3 (DSM ACC2832). The composition can further comprise the cell lines Mel-XX4 (DSM ACC2829). The cell lines can be irradiated to produce cells having an apoptotic or necrotic phenotype.
Patent NZ-585015-A (NZ)
Title: A dental appliance elastically deformable to apply a correction force at a base of the crown
Inventor: GEENTY JOSEPH
IPC: A61C7/08
Filed: 2008-11-10
Abstract: A dental appliance (20) for correcting tooth alignment including a body (22) for seating on an arch of teeth. The body (22) is at least partially elastically deformable into a seated condition on the arch of teeth. The body (22) is constructed such that when seated on the arch of teeth a correction force is applied on one or more misaligned teeth by virtue of the elastic deformation. The correction force is applied at or adjacent a base of the crown of each misaligned tooth in a direction in which each misaligned tooth is to be moved to correct its alignment.
Patent NZ-596478-A (NZ)
Title: Application of machine learning methods for mining association rules in plant and animal data sets containing molecular genetic markers, followed by classification or prediction utilizing features created from these association rules
Inventor: CARAVIELLO DANIEL
IPC: G16B20/20
Filed: 2010-06-03
Abstract: 596478 Disclosed is a computer-implemented method of mining a data set with at least one feature created from at least one plant-based molecular genetic marker, to find at least one association rule, and utilising features created from these association rules for classification or prediction for one or more target features. The method includes: (a) detecting association rules; (b) creating new features based on step (a) and adding these new features to the data set; and (c) developing a model for prediction or classification for one or more target features with at least one feature created in step (b). The method also includes: (d) selecting at least one plant from the plant population for one or more target features of interest based on classification or prediction with the association rules.
Patent NZ-598564-A (NZ)
Title: A centralised and automated purchase reward method
Inventor: DUCKWORTH DAVID HOWARTH
IPC: G06Q20/00
Filed: 2009-08-06
Abstract: 598564 Disclosed is a system for sales promotion with a central promotions management system (A) and sales systems (B) at plurality of remote locations. The system includes at least one computer programmed to receive in a promotions management system (A) multiple sets of input parameters, each set corresponding with a financial incentives promotion including promotion parameters and sponsorship parameters for the promotion. The promotion parameters and sponsorship parameters send promotion parameters including merchants at which the financial incentive promotion will be available, the period of the promotion, sales criteria which define customer entitlement to an award and the financial incentive or rules generated from promotion parameters and sponsorship parameters to entities in a sales promotion system. The computer receives transaction data including customer, coupon, product, and price data from a customer transaction at a sales system (B). Rules are applied that are generated from the promotion parameters to the transaction data to determine if the transaction qualifies for an award. For each transaction qualifying for an award, award information is supplied to the customer. Rules are also applied that are generated from the sponsorship parameters to determine promotion sponsor and sponsor charges related to the award. Sponsor charges are then applied against accounts of promotion sponsors log transaction data, records of awards made and sponsor charges applicable to the awards made. Finally, the logged data is uploaded at intervals to the promotions management (A) system.
Patent NZ-601188-A (NZ)
Title: Woody plants having improved growth characteristics and method for making the same using transcription factors
Inventor: HERTZBERG MAGNUS
IPC: A01H5/00
Filed: 2008-12-18
Abstract: 601188 Disclosed is a method of producing a tree having n increased growth and/or biomass compared to its wild type, comprising increasing in the tree the level of a gene product of at least one gene comprising a nucleotide sequence selected from the group consisting of a) nucleotide sequence SEQ ID NO 3; and b) a nucleotide sequence being at least 70% identical to nucleotide sequence SEQ ID NO 3. Further disclosed is transgenic tree comprising a recombinant polynucleotide (DNA construct) comprising a nucleotide sequence selected from the group consisting of: a) nucleotide sequence SEQ ID NO: 3; b) a complementary nucleotide sequence of the nucleotide sequence of a); c) a nucleic acid sequence being at least 70% identical to any one of the sequences in a) or b); d) a nucleotide sequence which hybridizes under stringent conditions to a nucleotide sequence of a) or b); and wherein the recombinant DNA construct further comprises a constitutive, inducible, or tissue specific promoter operably linked to said nucleotide sequence. The abovementioned nucleotide sequence encodes the peptide of the following sequence: MEIKESERVVIAKPVASRPSYSNFTSFSELLAGAINTTPSNVCSGTAVAAIRPKTVRFRPLVNRAPGALVSSQAGLSGTAVSNSFNKASSTDSKATIIYKPQAKLVSKATVSLLANMGNFNTNSQQMLQPVETRPQLSKQDKHNFSSQLTSNPHQNIPSPAEADHTTEPLRLTSLNQEEDPKTLSHASNGDRPSYDGYNWRKYGQKQVKGSEYPRSYYKCTYPNCPVKKKVERSFDGQIAEIVYKGEHNHSKPQPPKRNSSGTQGLSDGNAPDRNSIPLWSNQLNERNEGSEGREENQNEIGLPVHSIYQGKAPPSYDPAGTGTINAGTGTSDNSCGVSGECDDGSKGLEGANDEPKSKRRKTEIQSTEGGMSGEGVQEPRVVVQSSTDSEILGDGFRWRKYGQKIVKGNPYPRSYYRCTSIKCNVRKHVERVSDDPRAFITTYEGKHNHEIPLKSTNLAAFEPDSQAPTTRVKQ.
Patent NZ-603225-A (NZ)
Title: Methods and lipid compositions for promoting development of gut flora
Inventor: BAR-YOSEPH FABIANA
IPC: A23L33/00
Filed: 2011-04-26
Abstract: 603225 Disclosed is a method of inducing and promoting development of beneficial gut flora in a subject and/or of reducing the frequency and duration of crying periods in a subject, the method comprises administering to the subject a lipid composition comprising a vegetable-derived fat source, wherein the fat source is a triglyceride fat source comprising triglycerides with 15-55% palmitic acid moieties out of the total fatty acids, and wherein the level of palmitic acid moieties at the sn-2 position of the glycerol backbone is at least 30% of total palmitic acid. The method is particularly intended for children. Specific fat sources, as well as food articles and a commercial package comprising the same are disclosed.
Patent NZ-607801-A (NZ)
Title: Gas stream purification apparatus and method
Inventor: SUCHAK NARESH J
IPC: C01B32/50
Filed: 2011-06-23
Abstract: 607801 A method for removing contaminants from a gas stream, comprising: (a) introducing the gas stream into a reaction chamber (11) of a scrubber (10); (b) oxidizing first contaminants in a liquid phase with a reactive species in a sump (14) of the scrubber (10) for providing an oxidizing solution; (c) oxidizing second contaminants in a gas phase of the gas stream above the sump (14) with excess reactive species disengaging from the oxidizing solution in the sump (14); (d) oxidizing and scrubbing third contaminants in a gas-liquid contact assembly disposed above the gas stream. The steps (b) – (d) occur simultaneously.
Patent NZ-608004-A (NZ)
Title: Improved storage apparatus
Inventor: HARDIE JOHN DAVID
IPC: B65D43/16
Filed: 2010-06-08
Abstract: A storage apparatus, having a receptacle with an open top, a lid (2) and balance means (6). The lid is able to cover the open top and comprises a horizontal pivot axis (21) at or adjacent the open top. The balance means are pivotable about an axis. Linking means (16) are provided such that a rotational moment is exerted by the balance means, via the linking means, on the lid. The moment is selectable to reduce the force needed to open the lid compared to if the balance means were absent. The centre of gravity of the lid is at a fixed distance from the pivot axis when the lid is closed. As the lid is raised the rotational moment of the weight of the lid, acting through the centre of gravity of the lid, about the pivot axis, and tending to close the lid, changes. The change is at a different rate than the change of the moment of the balance means, exerted on the lid via the linking means. The construction and arrangement being such that the lid requires progressively more opening force to raise it, when the opening force is applied at or near the edge of the lid furthermost from the pivot axis of the lid. The storage apparatus may be used as a stock feeding arrangement, particularly for cattle, wherein an animal may lift the lid to access the feed as required. The moment, provided via the linking means, may be selectable such that the force required to open the lid may be low, to facilitate training, or higher to prevent unwanted opening of the storage apparatus, e.g. by wind gusts.
Patent NZ-609146-A (NZ)
Title: Modified 4’-nucleosides as antiviral agents
Inventor: DU JINFA
IPC: C12P19/30
Filed: 2006-09-26
Abstract: The disclosure relates to a compound comprising a β-D- and β-L-nucleoside e.g. 4’-C-ethynyl-3’-fluoro -3’-deoxythymidine, 4’-C-ethynyl-3’-azido-3’-deoxythymidine or a pharmaceutically acceptable salt thereof, having a structure defined by formula (II) wherein the variables R1, R2, R3, A, X, Y and Z are as defined in the specification. These compounds are suitable for the treatment or prophylaxis of a host infected with human immunodeficiency virus (HIV) or hepatitis B virus (HBV).
Patent NZ-614603-A (NZ)
Title: Use of glycopyrrolate for treating tachycardia
Inventor: SNAPE SUSAN
IPC: A61P9/00
Filed: 2012-03-05
Abstract: Provided is the use of glycopyrrolate in the treatment of tachycardia. Further provided are inhalable pharmaceutical compositions comprising glycopyrrolate.
Patent NZ-615840-A (NZ)
Title: Low pour point renewable fuel blend
Inventor: ZHOU GUANGCI
IPC: C10L1/16
Filed: 2012-03-30
Abstract: A renewable fuel blend and a process for producing a renewable fuel blend are described. The blend includes biologically derived C13 to C18 normal paraffins, which are provided to the blend in quantities such that blend does not require a pour point reducing treatment to achieve a low pour point. In embodiments, the normal paraffins are produced in an upgrading process, such as a hydrotreating process.
Patent NZ-619683-A (NZ)
Title: Novel substituted indole derivatives as gamma secretase modulators
Inventor: GIJSEN HENRICUS JACOBUS MARIA
IPC: A61P25/28
Filed: 2012-07-12
Abstract: The present disclosure is concerned with novel substituted indole derivatives of Formula (I) wherein R1, R2, R3, A1, A2, A3, Y and X have the meaning defined in the claims. The compounds according to the present disclosure are useful as gamma secretase modulators. The disclosure further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
Patent NZ-628339-A (NZ)
Title: Compositions containing anthraquinone derivatives as growth promoters and antifungal agents
Inventor: SU HAI
IPC: A01P21/00
Filed: 2011-11-03
Abstract: Disclosed are methods for modulating root initiation and extension in a plant comprising: (a) treating a root of a plant with a composition comprising an anthraquinone derivative such as chrysophanol in an amount effective to modulate root extension when transplanted into soil and (b) transplanting the treated plant of (a) into soil. Also disclosed is a method for promoting germination of a seed of a plant comprising applying to said seed an amount of a composition comprising physcion effective to promote said germination of said seed of said plant and optionally a seed coating agent. Chrysophanol is also known as 1,8-Dihydroxy-3-methylanthraquinone, and 3-Methylchrysazin. Further disclosed is a composition for modulating germination comprising one or more anthraquinone derivatives.
Patent NZ-630560-A (NZ)
Title: Pharmaceutical compositions for combination therapy
Inventor: WATERS ROSS NICHOLAS
IPC: C07D471/04
Filed: 2013-04-03
Abstract: Disclosed is a pharmaceutical composition which comprises an amount of tetrabenazine or a pharmaceutically acceptable salt thereof, an amount of pridopidine or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable carrier, for use in treating a subject afflicted with a movement disorder such as Huntington’s disease, Tourette’s syndrome, or tardive dyskinesia.
Patent NZ-710192-A (NZ)
Title: Modulation of apolipoprotein ciii (apociii) expression
Inventor: MULLICK ADAM
IPC: A61P3/06
Filed: 2012-04-27
Abstract: Disclosed is the use of a compound targeting ApoCIII in the manufacture of a medicament for increasing HDL levels and/or improving the ratio of TG to HDL in an animal thereby increasing chylomicron clearance in an animal; wherein the compound comprises a modified oligonucleotide comprising or consisting of the sequence of SEQ ID NO: 3 and wherein the compound is capable of inhibiting apolipoprotein C-III. Further disclosed is the use of a compound comprising a modified oligonucleotide targeting ApoCIII comprising or consisting of SEQ ID NO: 3, wherein the modified oligonucleotide comprises: (a) a gap segment consisting of 10 linked deoxynucleosides; (b) a 5’ wing segment consisting of 5 linked nucleosides; (c) a 3’ wing segment consisting 5 linked nucleosides; wherein the gap segment is positioned immediately adjacent to and between the 5’ wing segment and the 3’ wing segment, wherein each nucleoside of each wing segment comprises a 2’-O-methoxyethyl sugar, wherein each cytosine is a 5-methylcytosine, and wherein each internucleoside linkage is a phosphorothioate linkage; and wherein the modified oligonucleotide is capable of inhibiting the expression of apolipoprotein C-III; in the manufacture of a medicament for increasing HDL levels and/or improving the ratio of TG to HDL in an animal thereby increasing chylomicron clearance in an animal.
Patent NZ-711637-A (NZ)
Title: A wheel
Inventor: ROSS GREGORY PRATT
IPC: B60C17/06
Filed: 2015-08-31
Abstract: A wheel, for example for a kayak trolley, having an axle hub 1, inner rigid spokes 2 and an outer tire. The tire has a series of flexible spokes 7 which are able to move when the tire is in use to cause a ground engaged section of the tire to assume a substantially flat track portion when under load, and to revert to a normal circular tending configuration when turned away from a ground engaging position.
Patent NZ-714757-A (NZ)
Title: Use of il-15 to increase thymic output and to treat lymphopenia
Inventor: BERGAMASCHI CRISTINA
IPC: C07K19/00
Filed: 2010-08-13
Abstract: Discloses a ploynucleotides sequence encoding an IL-15 receptor alpha (IL-15Rα)-Fc fusion protein comprising a soluble IL-15Ra that lacks the transmembrane anchor portion fused an immunoglobulin constant region.
Patent NZ-716549-A (NZ)
Title: Adeno-associated virus factor viii vectors
Inventor: COLOSI PETER
IPC: A61K48/00
Filed: 2014-09-10
Abstract: The invention provides improved adeno-associated virus (AAV) Factor VIII (FVIII) vectors, including AAV FVIII vectors that produce a functional Factor VIII polypeptide and AAV FVIII vectors with high expression activity.
Patent NZ-733310-A (NZ)
Title: Compositions for inhibiting masp-2 dependent complement activation
Inventor: DUDLER THOMAS
IPC: C07K16/40
Filed: 2012-05-04
Abstract: An isolated monoclonal antibody, or antigen-binding fragment thereof, that binds to human MASP-2, comprising a heavy chain variable region comprising the amino acid sequences set forth as amino acid residues 1 to 120 of SEQ ID NO:56, and a light chain variable region comprising the amino acid sequences set forth as amino acid residues 146 to 250 of SEQ ID NO:56.
Patent NZ-734971-A (NZ)
Title: Methods of treating pancreatic cancer
Inventor: DESAI NEIL
IPC: A61K31/337
Filed: 2014-01-10
Abstract: Disclosed is a method of treating metastatic or locally advanced pancreatic cancer in a human individual comprising administering to the individual (a) an effective amount of a composition comprising nanoparticles comprising paclitaxel and an albumin; and (b) an effective amount of gemcitabine, wherein the individual (i) had previously received a Whipple procedure or (ii) has a biliary stent.
Patent NZ-738112-A (NZ)
Title: Single-component high-anticorrosion quick-drying epoxy coating composition
Inventor: ZHOU XUESONG
IPC: C09D7/00
Filed: 2016-05-20
Abstract: A single-component high-anticorrosion quick-drying epoxy resin coating composition comprises epoxy resin and a solvent that comprises a mixture of cyclohexanone, methyl ethyl ketone, and butyl acetate, and the coating composition does not contain a curing agent. The coating composition serving as a primer coat is coated on at least one part of a metal substrate, and a topcoat is coated on at least one part of the primer coat, so as to obtain a coated substrate.
Patent NZ-755705-A (NZ)
Title: Enclosure assembly and metering apparatus comprising same
Inventor: CAKEBREAD ANDREW
IPC: G01R11/04
Filed: 2018-01-11
Abstract: An enclosure assembly comprising a first enclosure portion (10) and a second enclosure portion (11) that are assembled by being moved towards each other along an assembly direction (A). In a fully assembled state the assembly encloses at least a part of an inner space to accommodate a metering device. The assembly further comprises a fixation arrangement (13) for affixing the first enclosure portion to the second enclosure portion in a fixation position that prevents the first enclosure portion (10) and the second enclosure portion from being separated. The fixation arrangement comprises at least one latching element (15) arranged at the first enclosure portion and at least one counter latching element (16) arranged at the second enclosure potion. A latching nose (21) is arranged at a free end of the at least one latching element and protrudes therefrom in a latching direction (B) perpendicular to the assembly direction. A blocking element (25) prevents a disengagement of the at least one latching element and the at least one counter latching element, wherein in a deflected position of the at least one latching element, the latching nose abuts the at least one counter latching element in the latching direction, and the blocking element abuts the at least one latching element in a deflection direction (C) perpendicular to both the latching direction and assembly direction. The invention provides an simple to assemble latch that can guard against tampering by unauthorised persons.