baber/WOPTO huggingface dataset:
Patent MX-2022001158-A (MX)
Title: Dual atm and dna-pk inhibitors for use in anti-tumor therapy.
Inventor: FU JIANMIN
IPC: A61K31/444
Filed: 2020-07-30
Abstract: Provided herein are compounds of formula (I): and pharmaceutically acceptable salts thereof, where the substituents are as described herein. These compounds and their pharmaceutical compositions may be useful in the treatment of oncologic diseases.
Patent MX-2022001715-A (MX)
Title: Polyester polyol comprising an imide moiety and methods of manufacture thereof.
Inventor: WU LIFENG
IPC: C08G18/46
Filed: 2020-08-05
Abstract: A method of forming an aromatic polyester polyol compound comprising an imide moiety, wherein the method comprises reacting: (i) a cyclic anhydride compound; (ii) a phthalic acid based compound; (iii) a primary amine compound; and (iv) an aliphatic diol compound.
Patent MX-2022003281-A (MX)
Title: Composition for reconditioning, removing and dissolving scale/precipitated depositions inside closed heat transfer systems.
Inventor: DE LA FUENTE ARIAS WENDY
IPC: C09K8/52
Filed: 2022-03-17
Abstract: The present invention relates to a composition for chemical reconditioning closed heat transfer systems with continuous water circulation. It consists of a series of liquids based on organic and inorganic acids, surfactants, corrosion inhibitors, and biocides. Also, it is biodegradable, including neutralizers to eliminate scale and deposits that precipitate in closed refrigeration systems subjected to high temperatures in the presence of hard water. The process consists of taking the solid samples from natural heat transfer systems and analyzed through solubility tests/spectrophotometric analysis to verify their optimal performance at the laboratory level. Said dissolution improves efficiencies of up 69.11% to 72.12% for equipment from Field of Observation No. 1 and up 64.27% to 69.20% for equipment from Field of Observation No. 2. Further, said composition applies through continuous circulation at the level of engines in the field, obtaining solutions of up 78.80% to 98.57% for equip ment from Field of Observation No. 1 and up 89.30% to 99.63% for equipment from Field of Observation No. 2.
Patent MX-2022007635-A (MX)
Title: Antibodies binding to hla-a2/mage-a4.
Inventor: FAUTI TANJA
IPC: C07K16/30
Filed: 2020-12-17
Abstract: The present invention generally relates to antibodies that bind to HLA-A2/MAGE-A4, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
Patent MX-2022010020-A (MX)
Title: Use of compound in prevention and/or treatment of pathogen infection in animals.
Inventor: LIN XINGYU
IPC: A61K31/4439
Filed: 2021-06-11
Abstract: Disclosed is the use of a compound in the prevention and/or treatment of pathogen infection in animals. The compound is 4-(3-{2-amino-5-[2-(1-methyl-piperidin-4-yl)-thiazole-5-yl]-pyr idin-3-yloxymethyl}-phenyl)-2-methylbut-3-yn-2-ol, and has the structure as represented by formula (I) as follows. The compound can be used for effectively treating animal diseases (such as feline infectious peritonitis) caused by infection via pathogens (in particular viruses, such as coronaviruses) and improving the survival of animals, and can have better commercial value and application prospects in the field of veterinary drugs for resisting pathogens (in particular viruses, such as coronaviruses).
Patent MX-2022010599-A (MX)
Title: Bispecific antigen binding molecules that bind her2, and methods of use thereof.
Inventor: DALY CHRISTOPHER
IPC: A61K47/68
Filed: 2021-02-26
Abstract: Provided herein are bispecific antigen-binding molecules that bind HER2 and methods of use thereof. The bispecific antigen-binding molecules comprise a first and a second antigen-binding domain, wherein the first and second antigen-binding domains bind to two different (preferably non-overlapping) epitopes of the extracellular domain of human HER2. The bispecific antigen-binding molecules cluster on the surface of HER2 IHC2+ and IHC3+ cells, and are internalized into the cellular lysosomes. Also included are antibody-drug conjugates (ADCs) comprising the antibodies or bispecific antigen-binding molecules provided herein linked to a cytotoxic agent, radionuclide, or other moiety, as well as methods of treating cancer in a subject by administering to the subject a bispecific antigen-binding molecule or an ADC thereof.
Patent MX-2022014984-A (MX)
Title: Attenuating bacterial virulence by attenuating bacterial folate transport.
Inventor: INGEBRITSON ALAINA
IPC: A61K39/09
Filed: 2019-05-09
Abstract: The invention relates to bacterial infections, vaccines directed against those infections and bacterial vaccines. More particularly, the invention relates to vaccines directed against Streptococcus infections in pigs. Provided is a Î<i>FolT</i> mutant of a bacterium having reduced capacity to transport folate, wherein the capacity has been reduced by functionally deleting folate transporter (FolT) function. Also provided is a method to reduce virulence of a bacterium comprising reducing the capacity of the bacterium to transport folate.
Patent MX-PA00009051-A (MX)
Title: Medication processing system and method.
Inventor: ROCK KELLY
IPC: B01F25/74
Filed: 1999-03-11
Abstract: This disclosure relates to a centrifugal vortex system for preparing a liquid, such as medicine, and includes a chamber housing defining a vortex chamber. An array of tangential apertures are formed in the chamber housing to permit fluid to be turbulently introduced into the vortex chamber to create a vortical flow of fluid through the vortex chamber. In one embodiment, a plurality of vortex chambers are arranged in series to allow the fluid to pass through several vortex chambers. In other embodiments, the chamber housing may be stepped, textured, or both to increase the turbulence of the flow through the chamber. This present invention may be used for nebulizing and vaporizing fluids, powders and liquids for inhalation by a patient.
Patent MX-PA00011163-A (MX)
Title: Control method for an industrial robot.
Inventor: GRAESER RALF-GUNTER
IPC: G05B19/00
Filed: 1999-05-14
Abstract: The invention relates to a method for controlling an industrial robot and, more particularly, to a method for reducing thermal influencing variables, whereby reference measuring points are arranged in the working area of the robot, which are traversed by the robot. The actual data of the reference measuring points is processed by a computer with the purpose of obtaining correction data that is fed to the control electronics of the robot. According to the invention, an error model is configured that corrects thermal positioning and/or orientation errors without having to determine the actual temperature on the robot.
Patent MX-PA01003775-A (MX)
Title: Controlled release fertilizer compositions and processes for the preparation thereof.
Inventor: TIJSMA EDZE JAN
IPC: C05G3/00
Filed: 1999-10-12
Abstract: A controlled release fertilizer is provided which exhibits a Gaussian nutrient release rate pattern. The fertilizer composition includes a granular nutrient core material having a single layer coating of a substantially water-insoluble, uniform, substantially continuous polymer film thereon. Processes are also provided for producing the fertilizer compositions. Methods are also provided for treating plants with the fertilizer compositions.
Patent MX-PA01010215-A (MX)
Title: Cord clamp.
Inventor: JOHN S PONTAOE
IPC: F16G11/14
Filed: 2001-10-09
Abstract: A cord clamp having a housing with first and second matable body portions, first and second side-by-side cord accommodating passages extending at least partially trough the housing from both opposite ends thereof. In some embodiments, a plurality of cord retaining teeth protrude into one of the passage, and in some embodiments one or both of the passages are devoid of cord retaining teeth and include a passage constriction for adjustably capturing a corresponding cord portion. A hinge may interconnect the first and second body portions at one end thereof, preferably between the passages.
Patent MX-PA02003978-A (MX)
Title: Surface catalyst infra red laser.
Inventor: ANTHONY C ZUPPERO
IPC: H01S3/09
Filed: 2000-10-19
Abstract: A process and apparatus are provided for the generation of laser radiation by providing a fuel (105), such as methanol, ethanol, carbon monoxide and or hydrogen, and air (106) to a catalyst (102), such as platinum, which is located beneath a polychromatic resonant optical cavity formed by laser mirrors (107) and (108). The catalyst surface is flooded with adsorbed fuel radicals, leaving relatively few sites for oxygen adsorption. Under this condition, the oxygen dissociates into two oxygen atoms or free radicals with approximately one electron volt of energy (i.e. hot atoms). These hot atoms of oxygen find fuel radicals as collision partners and form reaction products that are in their highest vibrational state. A vibrationally inverted population is a prerequisite of stimulated emission of radiation.
Patent MX-PA02005077-A (MX)
Title: Human heparanase-related polypeptide and nucleic acid.
Inventor: GERHARD SIEMEISTER
IPC: C12N5/10
Filed: 2000-12-18
Abstract: The present invention relates to newly identified polynucleotides, and polypeptides encoded by such polynucleotides, the use of such polypeptides, as well as the production of such polynucleotides and polypeptides. More particularly, a polypeptide of the present invention is a heparanase-related endoglucuronidase. The invention also relates to vectors and host cells comprising a polynucleotide of the invention. Furthermore, the invention relates to antibodies directed to polypeptides according to the present invention and to pharmaceutical compositions and diagnostic reagents comprising such antibodies, polypeptides or polynucleotides. The invention further relates to a method of altering, modifying or otherwise modulating the level of expression of the heparanase-related endoglucuronidase in a cell or in a organism. A further aspect of the invention are assay systems suitable for identifying modulators, e.g. agonists or antagonists of such polypeptides.
Patent MX-PA02006672-A (MX)
Title: Novel therapeutic use of enoxaparin.
Inventor: MARY VERONIQUE
IPC: A61K38/00
Filed: 2001-01-03
Abstract: The invention concerns the use of enoxaparin for treating cerebral ischemia.
Patent MX-PA02007310-A (MX)
Title: A system and method for rewriting a media resource request and or response between origin server and client.
Inventor: LAHR NILS
IPC: G06F17/30
Filed: 2001-01-29
Abstract: A distributed network which is capable of dynamically changing media resource request metafiles, as well as the responses to those media resource requests by media servers in the network, to provide more efficient content delivery in the network. The network employs a system and method for intercepting a media resource request metafile client request, or a response to the media resource request by a media server in the network, and intelligently rewriting the response before sending it back to the requesting client. The file or protocol response can be rewritten according to localized information such as resource availability and client request information which the centralized web server may not have or even be able to obtain, such as the client's ISP, browser type, ISP's surfing trends and so on. The system and method thus enables the network to send the local client to either a local server or a remote server to receive the requested content.
Patent MX-PA02007947-A (MX)
Title: Aqueous wrinkle control compositions dispensed using optimal spray patterns.
Inventor: FRANKENBACH GAYLE MARIE
IPC: D06M15/11
Filed: 2001-02-13
Abstract: The present invention relates to selecting dispensers having optimal spray patterns for use together with aqueous wrinkle removal and or reduction compositions to minimize the potential to stain fabrics and significantly reduce drying time associated with aqueous based wrinkle control compositions. The present invention also relates to wrinkle control compositions suitable for use in dispensers with optimal spray patterns and articles of use including instructions for use. The present invention also relates to methods of use for wrinkle control compositions in dispensers with optimal spray patterns.
Patent MX-PA02008811-A (MX)
Title: High strength polymers and aerospace sealants therefrom.
Inventor: JORDAN DAVID W
IPC: C08G75/04
Filed: 2001-03-09
Abstract: A polythioether is provided of the formula (1) wherein R1 is H, C1 6 alkyl, C1 6 alkyl alcohol, C1 6 alkyl substituted with at least one of: (CH2)2 O Y O CHCH2 or formula (2), NHR5 wherein r5 is a C1 6 alkyl, R2 is C2 6 alkyl, C6 8 cycloalkyl, C6 10alkylcycloalkyl, [ (CH2)r Q ]s (CH2)t , or C1 2 alkyl substituted forms thereof, wherein r is an integer value from 2 to 8, Q is a heteroatom selected from the group consisting of: O, S, NH and NCH3 , s in an integer value from 1 to 5, and t is an integer value from 2 to 10, R3 is H or C1 4 alkyl, R4 is CH2 or R2, M is a C1 10 alkyl, C6 20 aryl, C6 20 aryl substituted with at least one C1 8 alkyl group, or a N or O heteroatom, Y is C2 20 alkyl, C6 20 cycloalkyl, C6 10 alkylcycloalkyl, or [ (CH2)r Q ]s ( CH2 )t , n is an integer value from 1 to 60, m is an integer value from 1 to 60, an p is an integer value from 1 to 10, wherein the polythioether has a viscosity at 20 C of less than 1000 poise.
Patent MX-PA03000004-A (MX)
Title: Method of providing a thermally-processed commodity within a plastic container.
Inventor: CALENDINE GEORGE
IPC: B65B3/02
Filed: 2001-06-29
Abstract: A method for providing a thermally processed commodity in a plastic container. The container is exposed to elevated temperatures to form an intermediate finish section. A commodity is dispensed within the plastic container. A closure engages the intermediate finish section. The finish cection being within a predetermined range whereby the finish section and the closure result in retaining a hermetic seal.
Patent MX-PA03008702-A (MX)
Title: Iron comprising a water filling slide valve.
Inventor: CEDRIC BONTEMS
IPC: D06F75/14
Filed: 2003-01-30
Abstract: The invention relates to an iron. The inventive iron consists of a liquid container (6) comprising an inlet (7) which is fitted with means of receiving and guiding the liquid through said opening towards the container. Preferably, the aforementioned means comprise a part (9) in the form of a slide valve or chute. Moreover, said means, which pass through the opening, can move in translation between a first open position, whereby the liquid can be introduced, and a second closed position, whereby the means are retracted into the iron in order to close the opening (7).
Patent MX-PA03012009-A (MX)
Title: Article having a plasmapolymer coating and method for producing the same.
Inventor: KLAUS D VISSING
IPC: B05D7/24
Filed: 2002-06-28
Abstract: The invention relates to an article that comprises a substrate, and a plasmapolymer coating applied across the surface of the substrate and comprising silicon, oxygen and carbon. An analysis by ESCA gives an amount of substance ratio for O:Si greater than 1.25 and less than 2.6, and the amount of substance ratio for C:Si is greater than 0.6 and less than 2.2. According to a preferred embodiment, the coating contains, based on its total atom content without hydrogen and/or fluorine, a minimum of 22 and a maximum of 27 atomic percent of Si, a minimum of 25 and a maximum of 50 atomic percent of O, and a minimum of 25 and a maximum of 50 atomic percent of C.
Patent MX-PA04000592-A (MX)
Title: Method and system for weld process monitoring.
Inventor: JOHN D NASTASI JR
IPC: G01B21/24
Filed: 2002-07-19
Abstract: A weld tip testing head (30) is presented. An alignment member has an aperture (58) disposed therein and is coupled to a spring element (53). The spring element (53) is further coupled to a mounting (50). The aperture (58) is operable to removably receive a weld tip (22) and the alignment member (30) is operable to determine an alignment associated with the weld tip (22). Computer software is encoded on storage. The computer software is operable to receive the alignment from the alignment member (30) and analyze the alignment with respect to at least one expected alignment value. The computer software is further operable to generate an alarm based on the analysis and generate a fault based on the analysis.
Patent MX-PA04002886-A (MX)
Title: Nicotinic acid-heterocyclyl-amides and analogous pyrimidine derivatives serving as pesticides.
Inventor: DANIELA JANS
IPC: C07D213/82
Filed: 2002-09-14
Abstract: The invention relates to amides of formula (I) and to the salts thereof, whereby the symbols and indices have the following meanings: X represents CH or N; Y represents O or S; n is 0 or 1; R 1 represents (C 1-C 4) alkyl halide; R 2 and R 3, independent of one another, represent hydrogen, (C 1-C 4) alkyl, (C 1-C 4) alkyl halide or halogen; R 4 represents hydrogen, (C 1-C 10) alkyl, (C 3-C 10) cycloalkyl, (C 3-C 10) alkenyl or (C 3-C 10) alkynyl, whereby up to three hydrogen atoms can be replaced by halogen in said alkyl, cycloalkyl, alkenyl or alkynyl groups and, in the case of fluorine, also up to the maximum number; R 5 is an aliphatic heterocycle containing at least one oxygen, sulfur, nitrogen and/or silicon ring atom, which is optionally substituted by one to six monovalent groups and which can optionally be part of a spirocyclic, condensed or bicyclic ring system. These compounds can be used for producing pesticides.
Patent MX-PA04003248-A (MX)
Title: Liquid dispensing closure.
Inventor: DOUGLAS S MARTIN
IPC: B29C33/00
Filed: 2002-09-27
Abstract: A liquid dispensing closure for bottles and the like comprising a one-piece body (10) having an end wall (13) for covering the mouth of the bottle (11) and a depending skirt for threading onto the neck of the bottle (11). A dispensing aperture (28) in the end wall (13) is surrounded by a spout (29) that affords directional control of a stream of liquid being dispensed and reduced dribbling when dispensing is discontinued. A flap (26) is hinged on the end wall to open and close the aperture (28) with an associated depending plug that fits in the spout (29). The end wall (13), spout (29) and hinged flap (26) are arranged in a manner relative to one another that permits the flap (26) to be advantageously molded in an upright position.
Patent MX-PA04005165-A (MX)
Title: Wireless electrocardiograph system.
Inventor: KENNETH SOLOVAY
IPC: A61B5/308
Filed: 2002-11-26
Abstract: A cardiac monitoring system and, more particularly, a wireless electrocardiograph (ECG) system. The present invention detects electrical signals from a patient's heart and transmits the signals digitally to a remote base station via telemetry. The base station converts the digital signals back to an analog electrical signals that can be read by an ECG monitor.
Patent MX-PA04005194-A (MX)
Title: Polycationic water soluble copolymer and method for transferring polyanionic macromolecules across biological barriers.
Inventor: LAIXIN WANG
IPC: A61K47/48
Filed: 2002-06-26
Abstract: The invention presents plycation-grafted copolymers exhibiting substantial water solubility and low toxicity. The copolymers can be used to deliver drug and other therapeutic agents to specifically targeted cells.
Patent MX-PA04007085-A (MX)
Title: Formulation for the administration of medicinal substances.
Inventor: MICHAEL JOHN DESMOND GAMLEN
IPC: A61K9/00
Filed: 2003-01-23
Abstract: A formulation for administration of a medicinal substance, comprises a sandwich biscuit having two or more biscuit layers that support filler layer(s), in which the filler layer comprises a dosage unit form, or a multiple or sub-multiple thereof, of a medicament that is unpalatable in having, for example, a gritty texture or a chalky texture or other unpleasant mouth feel. The biscuit layer of the sandwich biscuit may be a plain, non-medicated, biscuit layer or may itself contain a medicament. In the latter instance, it is possible to select a different medicament for the filler layer from that in the biscuit layer, whereby the two medicaments have a co-operating or synergistic effect. The formulations also allow large dosages of drugs to be administered effectively in a palatable form and are suitable for the long-term administration of drugs.
Patent MX-PA04008709-A (MX)
Title: Crystalline structure of human mapkap kinase-2.
Inventor: STEGEMAN RODERCK A
IPC: C12Q1/48
Filed: 2003-03-06
Abstract: The crystal structure of human MAPKAP kinase-2 is described, including the high-resolution X-ray diffraction structure and atomic structure coordinates obtained therefrom. A method of crystallization of MK-2 involving the use of a crystallization additive and the specific empirical conditions involved in this crystallization method is also described. This method of crystallization allows a resolution of about 3 Angstroms to be achieved. The tertiary structure of this protein as determined by X-ray crystallography to a resolution of 3 Angstroms is shown. Also described are methods by which the atomic structural information obtained from the MK-2 crystals can be used to screen for, identify and/or design new drugs.
Patent MX-PA04009347-A (MX)
Title: Solid fabric conditioning compositions.
Inventor: SARAH WYLDE
IPC: C11D1/62
Filed: 2003-02-28
Abstract: A solid fabric conditioning composition comprises a cationic fabric softening agent, one or more carrier materials, perfume and a deposition aid for depositing the cationic fabric softening agent onto fabrics during a laundry treatment operation wherein the deposition aid is citric acid or a salt of citric acid.
Patent MX-PA04009594-A (MX)
Title: Security document with marker.
Inventor: SANDRINE RANCIEN
IPC: B42D15/10
Filed: 2003-04-03
Abstract: The invention relates to a self-adhesive or heat-sealable security document (V), which may be placed on an article (P), characterised in that the above comprises at least one support (1) which may be printed on the rear face thereof, the front face of said support being treated with a layer of self-adhesive or thermo-sealing glue and at least one marker (3) emitting a signal which is characteristic thereof, such that after sticking said document (V) to the article (P) by means of said layer of glue and on removing said document (V), at least a part of said marker detaches itself from the support (1). The invention further relates to a method for authentication of the article.
Patent MX-PA05001058-A (MX)
Title: Process for preparing a composition for the cosmetic treatment of keratinous materials on the basis of a pressurised fluid and cosmetically active liquid compounds entrapped in particles.
Inventor: GROLLIER JEAN FRANCOIS
IPC: A61K8/26
Filed: 2005-01-26
Abstract: The invention relates to a process for preparing a composition for the cosmetic treatment of keratin materials, wherein it comprises a step of percolating a fluid at a pressure of at least 3 bar through at least one cosmetically active compound in liquid form trapped with porous or surface-treated particles.
Patent MX-PA05001957-A (MX)
Title: Process for the manufacturing of frozen aerated products.
Inventor: POLL VAN DE JONKHEER THEODOOR
IPC: A23G3/02
Filed: 2003-08-01
Abstract: Frozen aerated products are produced by i) providing two separate forming elements, ii) providing at least one open cavity on a surface each forming element, iii) providing filling devices for filling said cavities with a frozen aerated material, iv) filling two cavities, one on each moulding surface, with a frozen aerated material, wherein at least one of the cavities is filled with a frozen aerated product having an overrun of between 30% and 130%, this product is then allowed to expand outside its cavity, the two cavities are then moved opposite one another and the frozen aerated product in each cavity is pressed against the frozen aerated product in the other cavity.