baber/WOPTO huggingface dataset:
Patent EP-0705247-A1 (EP)
Inventor: SORENSEN PER OLAF
IPC: C07D211/60
Filed: 1994-06-22
Abstract: The present invention relates to therapeutically active azaheterocyclic compounds of formula (I), a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating a central nervous system ailment related to the GABA uptake. In said formula, A is a saturated or unsaturated five or six-membered carbocyclic ring optionally substituted with a phenyl, benzylidene, C1-4-alkyl substituted with phenyl or C2-4-alkenyl substituted with phenyl which phenyl or benzylidene is optionally substituted with halogen, C1-4-alkyl, C1-4-alkoxy or trifluoromethyl and which saturated or unsaturated five or six-membered carbocyclic ring may be optionally fused with a benzo ring.
Patent EP-0707579-A1 (EP)
Inventor: KLIMAS MICHAEL THADDEUS
IPC: A61P25/18
Filed: 1994-07-04
Abstract: Nouveaux composés de pipéridinyle représentés par la formule (I), dans laquelle X et Y sont sélectionnés indépendemment parmi hydrogène, halogène et alcoxy C1-6, R1 est sélectionné parmi des noyaux d'hétéroaryle à cinq et six constituants contenant de 1 à 3 hétéroatomes sélectionnés parmi azote, oxygène et soufre, ainsi que leurs dérivés benz pouvant porter 1-2 substituants sélectionnés parmi alkyle C1-6, hydroxy, alcoxy C1-6 pouvant porter un groupe trifluorométhyle, alcoxycarbonyle C1-6, hydroxyalkyle C1-6, benzyloxy, halo, alkylaminocarbonyle C1-3, alkyle C1-3, aminocarbonyle possédant la formule: CONR?cRd où Rc et Rd¿ sont sélectionnés indépendamment parmi hydrogène, 2-pirrolidinyle, et alkyle C¿1-6?, où R?c et Rd¿c, avec l'atome d'azote auquel chacun est fixé, constituent un noyau hétérocyclique à 5 ou 6 constituants dans lequel ledit azote est le seul hétéroatome, ReS(O)n, R?fNH et Rg¿S, où R¿e et R?f sont sélectionnés indépendamment parmi hydrogène et alkyle C1-6 et n est 0, 1 ou 2 et Rg est sélectionnée parmi alkylcarbomylaminophényle C¿1-3? et di(C1-3)alkylamino(C1-6)alkyle, où au moins un des substituants du noyau hétéroaryle à cinq et/ou six constituants est un sulfoxyde chiral représenté par la formule C1-4alkylSO, ainsi que leurs sels acceptables pharmaceutiquement, présentant une efficacité en tant qu'antagonistes de dopamine et, particulièrement, en tant qu'agents antipsychotiques chez l'homme. Ces composés peuvent également être efficaces dans d'autres maladies neurologiques et psychiatriques, y compris la schizophrénie. L'invention concerne également des procédés de préparation de ces composés de pipéridinyle, ainsi que leur utilisation en médecine.
Patent EP-0705330-A1 (EP)
Inventor: SCHNEPP KATHRIN
IPC: C11D3/08
Filed: 1994-06-13
Abstract: Extrudate mit einem verbesserten Redispergiervermögen können durch ein Verfahren hergestellt werden, bei dem ein festes Vorgemisch, welches ein Plastifizier- und/oder Gleitmittel enthält, unter Druck strangförmig verpreßt und der Strang nach Austritt aus der Lochform mittels einer Schneidevorrichtung auf die vorbestimmte Granulationsdimension zugeschnitten werden, wenn in dem festen Vorgemisch amorphe Silikate eingesetzt werden, wobei die amorphen Silikate: (a) mindestens teilweise als feste Zumischkomponente und als Plastifizier- und/oder Gleitmittel Wasser oder wäßrige Lösungen oder (b) mindestens teilweise in Form einer wäßrigen Lösung als Plastifizier- und/oder Gleitmittel eingesetzt werden. Dabei ist das Verfahren gemäß (b) bevorzugt. Die Silikate tragen auch zur Kornstabilität der Extrudate bei.
Patent EP-0706353-A1 (EP)
Title: Systeme implantable s'appliquant a la regulation du developpement cellulaire
Inventor: LYLES MARK
IPC: A61K9/22
Filed: 1994-07-01
Abstract: Un système implantable de protection contre les infections, et d'apport de médicaments dans un tissu vasculaire comprend un biomatériau fibreux, lié, poreux, relativement non biodégradable qui régule et dirige le développement cellulaire et l'angiogénie à partir d'un tissu vasculaire adjacent situé dans l'implant. Dans des modes de réalisation impliquant un système de protection contre les infections, ce dernier stimule le développement cellulaire et l'angiogénie à partir d'un tissu vasculaire adjacent qui bloque efficacement le passage de microorganismes pathogènes le long d'objets implantés par voie percutanée. Dans des modes de réalisation prévus pour l'administration de médicaments, un réservoir conçu dans le même biomatériau peut contenir soit (1) un système de culture cellulaire enfermé dans une chambre interne pouvant se fermer hermétiquement, poreuse, soit (2) une matrice biodégradable dans laquelle un ou plusieurs médicaments sont dispersés. Après l'implantation d'un réservoir du premier mode de réalisation dans un organisme, les cellules cultivées reçoivent la nourriture et l'oxygène via la diffusion dans un fluide tissulaire passant par les parois poreuses de la chambre interne, alors que les produits métaboliques, y compris les médicaments, se diffusent à partir de la culture cellulaire de manière analogue. Dans un réservoir du second mode de réalisation, une matrice biodégradable remplit pratiquement les pores (vides), et la dissolution progressive de la matrice libère un ou plusieurs médicaments dans le fluide tissulaire environnant. Les réservoirs de chaque mode de réalisation comprennent une pluralité de vides d'une taille prédéterminée, efficace, pour stimuler l'angiogénie à partir du tissu vasculaire environnant dans au moins une partie du réservoir. Le réservoir agit ainsi pour coupler une source de médicaments au système circulatoire de l'organisme.
Patent EP-0723666-A1 (EP)
Title: Use of estriol measurement to monitor tocolytic therapy
Inventor: DULLIEN VIVIAN K
IPC: G01N33/74
Filed: 1994-07-14
Abstract: A method of monitoring tocolytic therapy, which comprises determining a first concentration of estriol in a body fluid of a pregnant patient undergoing or diagnosed as a candidate for undergoing treatment with a tocolytic agent and, based on the value of the first concentration relative to a standard, either initiating, continuing, discontinuing, or modifying the treatment.
Patent EP-0711492-A1 (EP)
Title: Image display device
Inventor: HOLAKOVSZKY LASZLO
IPC: H04N13/00
Filed: 1994-07-25
Abstract: PCT No. PCT/HU94/00029 Sec. 371 Date Aug. 30, 1995 Sec. 102(e) Date Aug. 30, 1995 PCT Filed Jul. 25, 1994 PCT Pub. No. WO95/04435 PCT Pub. Date Feb. 9, 1995A head worn image display device, particularly TV picture display device, includes a TV screen or an image holder, and optical elements for transmitting a light beam from the screen or image to the eyes. The essence of the invention is that the device comprises optical elements dividing the beam starting from the screen (4) or image into beam branches, and directing the beam branches towards the eyes of a user of the device; optical elements reflecting the beam branches into the pupils (14,15); and focusing elements arranged between the reflecting optical elements and the pupils, and/or between the dividing optical elements and the reflecting optical elements.
Patent EP-0713474-A1 (EP)
Title: Method for controlling the swinging motion of an oscillating load and device for applying same
Inventor: EUDIER JEAN-YVES
IPC: B66C13/06
Filed: 1994-08-12
Abstract: PCT No. PCT/FR94/01005 Sec. 371 Date Feb. 13, 1996 Sec. 102(e) Date Feb. 13, 1996 PCT Filed Aug. 12, 1994 PCT Pub. No. WO95/05336 PCT Pub. Date Feb. 23, 1995Method and device for controlling the swinging motion of an oscillating load suspended from a movable support, wherein the movement of the support is controlled by a speed setpoint. The method includes a step (AS1) for automatically controlling the actual swaying value of the oscillating load by means of a zero swaying value and a step (37) for adjusting the speed setpoint (CV) of the support according to a correction value (E1) determined during the automatic swaying control step (AS1). The invention can be used, for example, for moving a load by means of a harbour crane.
Patent EP-0720625-A1 (EP)
Inventor: SCHIFFINO RINALDO SORIA
IPC: C08F2/06
Filed: 1994-08-18
Abstract: L'invention concerne un réacteur de polymérisation à temps de séjour court fonctionnant en mode périodique avec des alimentations multiples en catalyseur et des charges de monomères échelonnées, ce qui limite l'obtention de produits hors spécifications et optimise et module le poids moléculaire et la répartition des poids moléculaires du polymère produit. Cette invention concerne la polymérisation des oléfines, et notamment des alpha-oléfines, en particulier l'éthylène et le propylène, en homo-, co- et terpolymères.
Patent EP-0711348-A1 (EP)
Inventor: BOVENBERG ROELOF ARY LANS
IPC: C12P35/00
Filed: 1994-07-29
Abstract: PCT No. PCT/EP94/02544 Sec. 371 Date May 13, 1996 Sec. 102(e) Date May 13, 1996 PCT Filed Jul. 29, 1994 PCT Pub. No. WO95/04149 PCT Pub. Date Feb. 9, 1995An overall efficient process for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via 3-(carboxyethylthio)propionyl-7-ADCA, using a Penicillium chrysogenum transformant strain expressing expandase in conjunction with acyltransferase, is provided.
Patent EP-0683232-A1 (EP)
Inventor: YUKIMUNE YUKIHITO
IPC: C12P17/02
Filed: 1994-11-09
Abstract: A process for producing a taxane diterpene which comprises culturing the tissue or cell of a plant that produces a taxane diterpene in the presence of at least one member selected from the group consisting of jasmonic acids, heavy metal compounds, heavy metal complex ions, heavy metal ions, amines and ethylene-resisting agent; another process for producing a taxane diterpene which comprises culturing the tissue or cell by controlling the condition from the outset such that the oxygen concentration in the gas phase within the culture vessel is lower than the atmospheric oxygen concentration or that the dissolved oxygen concentration in the flowable medium in contact with the tissue or cell is lower than the saturation dissolved oxygen concentration at that temperature; still another process for producing a taxane diterpene which comprises culturing the tissue or cell in a culture tank by flowing into the tank an oxygenic gas containing 0.03-10 % of carbon dioxide; and a method of harvesting a cultured cell capable of producinga taxane diterpene in a high yield which comprises distributing the cells among a number of layers on the basis of a difference in specific gravity, culturing the cells contained in at least one of the layers, and selecting the target cell from among the cells thus cultured. The invention permits industrial production of taxane diterpenes such as taxol useful as a cancer remedy.
Patent EP-0685090-A1 (EP)
Inventor: SIMS NATHANIEL M
IPC: G06Q10/06
Filed: 1994-11-01
Abstract: Les endroits où se trouvent une pluralité d'appareils (12a-12g) sont l'objet d'un suivi à l'aide d'un réseau (14) de liaisons d'intercommunication (16a-16d) dont chacune correspond à un endroit. On attribue à chacun des appareils (12a-12g) une étiquette (30a-30g), qui permet de les identifier les uns par rapport aux autres et qui peut être connectée à une liaison d'intercommunication (16a-16d) lorsque l'appareil concerné (12a-12g) se trouve à un endroit auquel la liaison (16a-16d) correspond. Chaque étiquette (30a-30g) reliée à une liaison d'intercommunication correspondante (16a-16d) est détectée et la situation de chacun des appareils (12a-12g) est déterminée sur la base de cette détection. L'invention permet également de déterminer l'état de fonctionnement des appareils (12a-12g) par corrélation d'une ou de plusieurs liaisons d'intercommunication (16a-16d) avec les états de fonctionnement respectifs. Cette technique est facile à utiliser et s'avère extrêmement efficace dans le suivi des appareils (12a-12g) stockés en différents points d'une installation. La localisation et l'état de fonctionnement des appareils (12a-12g) sont surveillés en continu, ce qui réduit le risque qu'un appareil (12a-12g) puisse être sorti du stock (18) sans que cela ne soit détecté.
Patent EP-0688809-A1 (EP)
Inventor: SERAFINI TITO T
IPC: C07D209/48
Filed: 1995-02-03
Abstract: A method for forming a homogeneous, concentrated, prepolymer composition, and a method of using the concentrated prepolymer composition to uniformly coat fibers is described. The prepolymer mixture is formed by dissolving a dialkyl, trialkyl, or tetraalkylester of biphenyltetracarboxylic acid in a solvent comprising ethyl acetate and methanol in a molar ratio of from about 1:3 to about 1:60, to form an ester solution. Diamine and end cap compound are added to the ester solution to form a monomer mixture solution. The end cap compound is a divalent compound characterized by (i) at least one unsaturated moiety, (ii) capable of reacting with the diamine or the ester to form an end cap radical that precludes further reaction of the diamine with the ester, and (iii) capable of undergoing addition polymerization. A portion of the solvent is evaporated from the monomer solution to form the substantially homogeneous, concentrated, prepolymer composition. The concentrated prepolymer composition is used to uniformly coat fibers by heating the composition to an elevated temperature to form a prepolymer melt and applying the prepolymer melt to fibers. An article of manufacture comprising fibers and polyimide can be formed by heating the prepolymer coated fibers to the cross-linking temperature of the prepolymers.
Patent EP-0669352-A1 (EP)
Inventor: BLUM HARALD DR
IPC: C08G18/44
Filed: 1995-02-13
Abstract: Aq. dispersions of polyester-polyurethanes (PES-PU) (I) with an acid no. of 5-60 mg. KOH/g. an OH gp. content of 0.25-6.5 wt.% and a urethane gp. contg. 2-25 wt.% (all w.r.t. solid I), comprise the opt. partly neutralised reaction prods. of (a) 15-90 wt.% linear polyester-polyol(s) with a mol. wt. of 500-4000 other than ester gp.-contg. polyols of type (b), (b) 4-75 wt.% linear polyol(s) comprising (i) OH-contg. polycarbonates with mol. wt. of 400-6000, (ii) OH-contg. polyether-polyols with mol. wt. of 350-3500 contg. less than 30 wt.% ethylene oxide (EO) units (w.r.t. all alkylene oxide units) and/or (iii) ester gp.-contg. polyester-polyols obtd. by hydrogenation of COOH to OH gps., alkoxylation of COOH gps. or esterification of COOH with low-mol. wt. diols from dimer fatty acids, (c) 1-10 wt.% hydroxycarboxylic, aminocarboxylic and/or aminosulphonic acid(s) or alkali salts thereof, (d) 0-20 wt.% cpd(s). of mol. wt. 60-300 contg. at least 2 OH and/or amino gps., (e) 0-20 wt.% hydrophilic mono- or poly-hydric alcohol(s) contg. EO units with mol. wts. of 350-3000, and (f) 5-50 wt.% of a polyisocyanate component contg. polyisocyanate(s) of mol. wt. 168-1000, at least 50 wt.% of which consists of diisocyanates with a mol. wt. of 168-300. Also claimed are aq. coating materials (opt. contg. normal additives etc.) contg. as polyol component, a mixt. of 25-100 wt.% (I), and 0-75 wt.% other binder(s), together with a crosslinker resin.
Patent EP-0656207-A1 (EP)
Inventor: FASSBERG JULIANNE
IPC: A61K9/00
Filed: 1992-06-08
Abstract: An aerosol formulation contains mometasone furoate and as propellant 1,1,1,2,3,3,3 and is suitable for treating asthma by nasal or oral administration.
Patent EP-0675549-A1 (EP)
Inventor: WATANABE ISAO C O NEC CORP
IPC: H01L31/0352
Filed: 1995-03-22
Abstract: A semiconductor device according to the invention includes an electric field buffer layer, a superlattice multiplication layer and a cap layer, they been laminated. Around a mesa side surface, a round shape p⁺ region is formed to have a width of several µm by doping p⁺ to below the field buffer layer, and then the cap layer is etched so that the p⁺ region is not in contact with the cap layer. This makes a distance of several µm between the inner surface of the p⁺ region and the external surface of the cap layer.
Patent EP-0688852-A1 (EP)
Inventor: STANEK RICHARD DR
IPC: C09K21/14
Filed: 1995-06-16
Abstract: An intumescent impregnant for porous substrates is wholly made up of, by wt.: (A) 5-60 (pref. 10-30)% P-contg. salts of urea cpds.; (B) 5-60 (pref. 10-40)% alcohol-etherified UF or MF resins; (C) 5-40 (pref. 5-20)% polyalcohols or carbohydrates; (D) 2-12 (pref. 4-18)% water-soluble amines, polyamines, imines, polyionines and/or polyalkylene imines; (E) 0-5 (pref. 2-4)% high boilers; (F) 0-5 (pref. 1-2)% conventional additives such as wetting agents, defoamers, thickeners or dyes; and (G) 10-40 (pref. 20-50)% water.
Patent EP-0702232-A1 (EP)
Inventor: MORITA KENICHI
IPC: G01N33/52
Filed: 1995-07-25
Abstract: Assessing human hair damage comprises immersing a sample of the hair in a soln. of an anionic dye having a pH of 1-5 and visually determining the degree of damage on the basis of the colour change.
Patent EP-0685158-A1 (EP)
Inventor: HSU JEMIN CHARLES
IPC: A01N47/12
Filed: 1989-12-19
Abstract: Synergistic biocidal compositions of 2- n -octyl-3-isothiazolone and 1,2-dibromo-2,4-dicyanobutane are disclosed.
Patent EP-0760559-A1 (EP)
Inventor: RAY LAWRENCE ALLEN
IPC: H03M7/30
Filed: 1995-08-28
Abstract: In a string of characters on a storage medium in which a normally reserved character can appear in an inappropriate position, the field of characters is examined for a character which is not used in the field. The inappropriate reserved character is replaced by the permissible character. A field in the character string is reserved to permit the permissible character to be translated into the reserved character after the decoding of the character string.
Patent EP-0780057-A1 (EP)
Inventor: ANDERSSON BO
IPC: A23L3/36
Filed: 1995-12-21
Abstract: The present invention relates to a method and an apparatus for freezing of material into blocks, and to such frozen blocks. The apparatus comprising cooling means (11) and motion means (12) to pass a sheet or belt (13) along said cooling means (11), characterised in that the apparatus (10) further comprises at least one flexible, material receiving mould comprising at least one upwards and downwards open compartment (15), conveying means (16) to convey said mould, along the refrigerating panel (11) on top of the sheet or belt (13) acting as a base in the compartment (15) in at least part of said passage, and bending means (17) to bend said moulds (14) to release the block in the compartment (15).
Patent EP-0700843-A1 (EP)
Inventor: VAN ZIJDERVELD GEORGE JOHANNES
IPC: B65G17/06
Filed: 1995-09-08
Abstract: A conveyor chain manufactured from plastic, which is adapted to move at higher speeds than has been conventional heretofore and which is consequently particularly suitable to be used in a conveying system together with a conveyor mat to take over products from this mat or feed them to it. The chain has as a specific property that the front edge and the rear edge of the bearing surface of the chain link are of curved, preferably elliptically-shaped, design in the plane of the bearing surface, that the single hinge eye at the rear edge of the bearing surface has an upper surface which extends in the same plane as the bearing surface and which engages through a convexly shaped end in a correspondingly shaped recess in the bearing surface of the adjacent link coupled thereto through the hinge pin. By these measures the transition of products to and from the chain proceeds extremely smoothly at high speeds too.
Patent EP-0719826-A1 (EP)
Inventor: CARTER STEPHEN J
IPC: C08K5/053
Filed: 1995-12-14
Abstract: An ethylene polymer composition comprising per 100 parts by weight of ethylene polymer from 0,05 to 5 parts by weight of a diol containing at least one hydroxymethyl (-CH 2 OH) radical.
Patent EP-0687600-A1 (EP)
Inventor: ROGERS MARK
IPC: B60R21/216
Filed: 1995-06-13
Abstract: A fastening method and apparatus for attaching an air bag module cover (22) to a passenger air bag module reaction canister and over an automotive vehicle instrument panel air bag deployment opening. A first end of one or two straps (28, 30) at each end of the module is connected to an integral cover flange (34, 40) by a rivet (32, 38). A second end of each strap (28, 30) is connected to a module end plate (26) by a stud (42). Each strap (28, 30) has a weakened portion (56) adjacent the cover (22) and has physical characteristics which permit the cover flanges (34, 40) to engage with a ledge (46, 50) bounding the opening before the module is fully seated against a support structure (54). Flexibility between the cover and the reaction canister is provided and tolerant stack-up problems can be avoided.
Patent EP-0694302-A1 (EP)
Inventor: HORROBIN D F
IPC: A61K/
Filed: 1995-06-26
Abstract: Use of 6-desaturated n-6 fatty acids, especially gammalinolenic acid (GLA), dihomogammalinolenic acid (DGLA) or arachidonic acid (AA), together with a pharmaceutically acceptable material reducing intracellular levels of sorbitol in the body, particularly an aldose reductase inhibitor, in the treatment of (including prophylactic treatment), and in the preparation of medicaments for the treatment of (including prophylactic treatment), the long-term complications of diabetes mellitus. Pharmaceutical compositions of said materials. The ascorbate esters of 6-desaturated n-6 fatty acids (other than GLA or DGLA)  per se .
Patent EP-0672631-A1 (EP)
Inventor: SOLNTSEV STANISLAV SERGUEVICH
IPC: C03C8/14
Filed: 1995-03-13
Abstract: A high temp. coating for esp. porous ceramic substrates comprises (a) a (prim.) barrier layer of compsn. (by wt.) 90-99.9% quartz glass and 0.1-10% silicon tetraboride (contg. more than 96 wt.% SiB4); and (b) a (final) emissive enamel layer of compsn. (by wt.) 95-98.5% high silica content glass and 1.5-5% silicon tetraboride (contg. more than 96 wt.% SiB4). Also claimed is a process for providing an esp. porous ceramic substrate with the above coating.
Patent EP-0685191-A1 (EP)
Inventor: BROSSIER JEAN
IPC: A47C17/16
Filed: 1995-05-03
Abstract: The clip (4) pivots (5) on the back of the seat frame (1), while its other end engages in notches (9,10) in the end of the back frame (3). A spring (7) moves the clip and lies between the end of the clip (6) and a point (8) on the seat frame. When the back frame is its horizontal position the clip engages in a recess (12), beyond the notches. The depth of the recess is sufficient to prevent any contact of the end of the clip with the edge (11) of the back frame. <IMAGE>
Patent EP-0778338-A1 (EP)
Inventor: RAPISARDA DARIO
IPC: C11D3/02
Filed: 1995-12-07
Abstract: The present invention is the use of sulphamic acid in a liquid acidic composition comprising another acid, for improved skin mildness.
Patent EP-0687242-A1 (EP)
Inventor: HALLER HERBERT
IPC: B65H1/02
Filed: 1994-12-06
Abstract: Pour effectuer l'amenée en continu d'articles plats, par exemple, d'enveloppes (K), à une machine de traitement, les articles sont placés de chant, de manière à être empilés sur un plateau (4) incliné vers l'avant, où ils sont alors supportés par une plaque d'appui (5) dont le bord supérieur est plus bas que les bords supérieurs des articles de la pile. Au-dessus de la plaque d'appui (5), il est prévu, dans son prolongement, une section transporteuse descendante (6) équipée d'organes transporteurs (7) se déplaçant dans le sens de l'acheminement des articles. Ces organes transporteurs (7) viennent en prise avec les bords supérieurs des articles, de façon que ceux-ci soient poussés vers le bas à travers une rainure (9) ménagée entre le plateau (4) et la plaque d'appui (5). Les articles sont ensuite repris par une section transporteuse (13) qui les dévie vers une zone terminale horizontale (2) du dispositif où ils forment une pile à partir du bas. La hauteur de cette deuxième pile est limitée à un niveau convenable de prélèvement, par arrêt temporaire, réglé de façon déterminée, du dispositif. Les organes transporteurs (7) sont opérants à de courts intervalles, successivement sur chacun des articles.