baber/WOPTO huggingface dataset:
Patent EP-1178966-B1 (EP)
Inventor: GIBSON KEITH HOPKINSON
IPC: A61K31/4706
Filed: 2000-05-03
Granted: 2003-10-22
Abstract: A compound of formula (I)or a pharmaceutically acceptable salt thereof; for use as a medicament wherein:n is 0-1;Y is selected from -NH-, -O-, -S-, or -NR<7>- where R<7 >is alkyl of 1-6 carbon atomsR<5 >is chloro or bromo;Y is selected from -NH-, -O-, -S-, or -NR<7>- where R<7 >is alkyl of 1-6 carbon atomsR<6 >is a specified cyclic group which may be substituted by various specified substituents,or R<6 >is a group -R<8>-X-R<9 >whereR<8 >is selected from various cycloalkyl, pyridinyl, pyimidinyl, or phenyl ring; any of which may be optionally subsituted as described,where X is selected from CH2, -NH-, -O-, -S-, CH2 or -NR<5>- where R<5 >is alkyl of 1-6 carbon atoms, and R<9 >is a group (CH2)mR<10 >where m is 0, or an integer of from 1-3 and R<10 >is an optionally substituted aryl or optionally substituted cycloalkyl ring of up to 10 carbon atoms,or R<10 >is a heterocyclic ring containing 1 or 2 oxygen atoms and optionally one or more substitutents; and R<1>, R<2>, R<3 >and R<4 >are each independently selected from hydrogen or various specified organic groups. Novel compounds are also described. The compounds are particularly useful in the inhibition of MEK enzymes.
Patent EP-1181852-B1 (EP)
Inventor: DALHEIMER VOLKER
IPC: G06F1/20
Filed: 2000-05-31
Granted: 2003-03-26
Abstract: The invention relates to a housing system for housing electronic components, especially a flat desktop PC or multimedia housing. A fresh-air duct is provided in the interior of said housing and is mounted substantially in parallel to the base plate and spaced apart therefrom at a predetermined height. Said fresh-air duct, apart from lateral air intake openings, is sealed from the housing and at the intake side of the chambers or section that are located in the interior of the housing. At the end of the fresh-air duct facing away from the air intake openings a recess is provided which accommodates the fan. Said fan blows vertically into the chamber below the fresh-air duct, the lower chamber communicating with a lateral exhaust duct. The warmed-up exhaust air is forced through said exhaust duct and is laterally discharged from the housing. In the flow direction below the fan at least one electronic component and one heat source are mounted against which the fan blows. A second recess in the fresh-air duct is located upstream of the recess in which the fan is accommodated. Said second recess accommodates a component to be cooled, said component extending into the lower chamber.
Patent EP-1187599-B1 (EP)
Inventor: LAHAV RAFFAEL
IPC: A61K9/00
Filed: 2000-06-21
Granted: 2008-03-26
Abstract: A stable composition with a benzimidazole derivative, such as Omeprazole, which does not contain a separating layer between the active compound and an enteric coating layer. Instead, the enteric coating layer is applied as a solution with a pH value of at least 6.5, and more preferably in a range of from about 7 to about 10, directly to the benzimidazole derivative substrate. This solution, with the optional addition of a plasticizer, can be directly coated onto the substrate without any necessity for an intermediate layer. Furthermore, in this pH range, the enteric coating is optionally applicable in an aqueous solution, thereby obviating the need for organic solvents for dissolving the enteric coating material. The resultant formulation maintains the stability of the benzimidazole derivative during storage and at the same time protects the product during passage through the acidic environment of the stomach.
Patent EP-1259556-B1 (EP)
Inventor: ARRIOLA DANIEL J
IPC: C08F8/12
Filed: 2000-06-14
Granted: 2006-06-07
Abstract: Silane functional polymers having uniform silane distribution, long chain branching or tertiary silane functionality and conversion thereof through coupling, hydrolysis, hydrolysis and neutralization, condensation, oxidation or hydrosilation are disclosed.
Patent EP-1202662-B1 (EP)
Inventor: HECHTL GEORG
IPC: A47L15/42
Filed: 2000-07-05
Granted: 2005-09-28
Abstract: The frontloading dishwasher has a dishwashing compartment and a door mounted on the machine body such that it can be pivoted about a horizontal axis for closing a loading opening of the dishwashing compartment. The bottom border of an inner wall of the door, forming a door lip, engages behind a compartment skirt that rises from the dishwashing-compartment base. A seal is arranged between the door and the dishwashing compartment. The seal includes a sealing strip that extends across the entire door width. Satisfactory sealing of the dishwasher is ensured over a long period of use, dirt deposits in the sealing region are avoided, and only a low level of force for moving the door is required in that a guide and securing device for the seal is provided, for securing the seal in the rest position and for guiding the seal during movement of the door.
Patent EP-1196626-B1 (EP)
Inventor: SHOKAT KEVAN M
IPC: C07D487/04
Filed: 2000-07-21
Granted: 2006-05-10
Abstract: The present invention provides a method for the identification of a pattern of changes in cellular responses induced by the selective inhibition of a signaling molecule, by determining the specific effects of a selective inhibitor on a mutant form of a signaling molecule on cellular responses. The pattern of alterations in cellular responses resulting from the inhibition by a selective mutant inhibitor of the mutant signaling molecule are characteristic of the cellular response alterations that a specific inhibitor of the wild-type signaling molecule will produce. After determining the pattern of cellular responses of the mutant cells with the mutant molecule, compounds may be identified capable of inhibiting the wild-type molecule by producing a pattern of cellular responses in wild-type cells matching or having similarity to that of the inhibition of the mutant molecule.
Patent EP-1242523-B1 (EP)
Inventor: CHYALL LEONARD J
IPC: C08K5/51
Filed: 2000-08-04
Granted: 2005-10-19
Abstract: An intumescent polymer composition includes a matrix polymer, an acid catalyst source, a nitrogen source and an ionic phyllosilicate synergist having substantial cationic exchange capacity. Particularly preferred ionic phyllosilicates are montmorillonoids whereas pentaerythritol phosphate is a preferred acid catalyst source:
Patent EP-1192368-B1 (EP)
Inventor: PREBECK STEFAN
IPC: F16H61/40
Filed: 2000-07-08
Granted: 2002-11-13
Abstract: A power-splitting transmission which consists of a hydraulic power branch (7) and a mechanical power branch. Leakage in the hydraulic power branch (7) as well as the activation apparatuses (12) in the mechanical power branch are supplied with a pressurized medium from a common pressure source (1). The common pressure source (1) transports pressure medium to the hydraulic power branch (7), through a damping apparatus (3), and simultaneously transports pressure medium to the activation apparatuses (12) of the shifting elements (13) of the mechanical power branch via a controller (11).
Patent EP-1203262-B1 (EP)
Inventor: KNOCKE FRANK
IPC: G03H1/22
Filed: 2000-08-03
Granted: 2005-12-28
Abstract: The invention relates to a device for projecting holographically saved information onto a projection screen (17), comprising a light source (11-13) for creating a light beam; a medium (14-16) containing individual projected images, saved holographically in a first direction, one next to the other and a projection screen (17) which is configured in such a way that it receives the light beam projected onto it in the first direction and scatters said beam in a second direction which runs transversely to the first. The light source (11-13), medium (14-16) and projection screen (17) are positioned in relation to one another in such a way that the light beam from the light source (11-13) falls onto the medium (14-16) and the light beam which is diffracted holographically by said medium, is projected onto the projection screen (17). The invention also relates to a device for exposing a holographic medium, comprising individual projected images, arranged next to one another in a first direction on the medium, elements for generating an object light beam which contains information about the individual projected images, a projection lens for projecting the object light beam onto an imaginary projection screen and an element for the gradual, relative displacement of the object light beam and the medium towards one another in the first direction.
Patent EP-1204765-B1 (EP)
Inventor: BERLIN KURT
IPC: C12Q1/6827
Filed: 2000-07-25
Granted: 2005-09-28
Abstract: A method is described for the relative quantification of the methylation of cytosine bases in DNA samples, wherein the following method steps are conducted: a) a genomic DNA sample is chemically converted with a reagent, wherein 5-methylcytosine and cytosine react differently and show a different base pairing behavior in the DNA duplex after the reaction; b) the DNA sample is amplified, whereby a fluorescently labeled dCTP or dGTP derivative is added; c) the amplified products are separated spatially from each other; and d) the fluorescence of the separated amplified products is measured quantitatively.
Patent EP-1207848-B1 (EP)
Inventor: SEEMANN RUEDIGER
IPC: A61K35/02
Filed: 2000-08-28
Granted: 2004-11-10
Abstract: The invention relates to a purifying and/or regenerating agent for external use and to a purifying method. The purifying agent contains a mineral powder of alumina, sea salt, minerals, algae and ethereal oils that are applied in the form of a slurry on a garment to be worn on the body surface.
Patent EP-1145070-B1 (EP)
Inventor: BROWN DAVID C
IPC: G02B26/10
Filed: 2000-11-01
Granted: 2005-08-10
Abstract: A galvanometer unit comprises a limited-rotation motor with a load element such as a mirror attached to a shaft extending from the motor. In a servo loop that controls the angular position of the mirror, a position-sensor attached to the shaft provides position feedback information. The sensor includes a rotor which is positioned at the null point of the fundamental torsional resonance mode of the rotating system, thereby essentially eliminating feedback components resulting from the resonance. If the motor armature is supported for rotation on ball or roller bearings, the controller for the motor causes complete rotation of the armature from time to time, thereby distributing bearing wear around the bearing races and prolonging the useful life of the bearings.
Patent EP-1156069-B1 (EP)
Inventor: INADA SHUJI
IPC: C08G63/78
Filed: 2000-10-18
Granted: 2006-05-31
Abstract: A method of producing a polyester from high-purity bis- beta -hydroxyethyl terephthalate as a raw material containing cations and anions in trace amounts. Polyester production raw materials including bis- beta -hydroxyethyl terephthalate containing cations and anions in a total weight of not more than 50 ppm, ethylene glycol and antimony trioxide and/or germanium dioxide as a polymerization catalyst are heated without substantially distilling off ethylene glycol and then heated under reduced pressure to be polycondensed while ethylene glycol is distilled off.
Patent EP-1228374-B1 (EP)
Inventor: GERL MARTIN
IPC: G01N33/74
Filed: 2000-10-25
Granted: 2005-03-16
Abstract: The invention relates to a process for detecting or determining a C-peptide-containing impurity in a sample of recombinantly produced human insulin or a derivative thereof, by a non-radioactive assay, comprising the steps: (a) preparing a sample of recombinantly produced human insulin or a derivative thereof; (b) mixing the samples with dilution buffer; (c) adding a tracer to mixture (b); (d) adding antibody specific for the C-peptide impurity to mixture (c); (e) adding "C-peptide second antibody bead" having at least one label to mixture (d); and (f) detecting or determining the presence of the C-peptide-containing impurity.
Patent EP-1230441-B1 (EP)
Inventor: HUEBEL EGON
IPC: C25D7/06
Filed: 2000-10-05
Granted: 2004-12-01
Abstract: For electrolytic treatment of electrically mutually insulated, electrically conductive structures 4 on surfaces of electrically insulating foil material (Fo), is unloaded from a store 15', 15'' , transported on a conveying line through a treatment unit 1 and brought in contact with treatment fluid F 1 . During transportation, the material Fo is guided past at least one electrode arrangement, having at least one cathodically polarised electrode 6 and at least one anodically polarised electrode 7 , both being brought in contact with the treatment fluid F 1 and being connected to a current/voltage source 8 . Current flows through the electrodes 6, 7 and the electrically conductive structures 4 . The electrodes 6, 7 are screened from each other so that substantially no electric current is able to flow directly between oppositely polarised electrodes 6, 7 . The material Fo is finally loaded back onto a store 15', 15''.
Patent EP-1242434-B1 (EP)
Inventor: RIEGER BERNHARD
IPC: B01J31/18
Filed: 2000-11-27
Granted: 2004-06-02
Abstract: New group VIIIB transition metal complex compounds have a bidentate bis((N-aliphatic and/or aromatic carbo- and/or heterocyclyl)-(N-heteroaryl- or -(heteroaryl)-aryl)-imine) chelate ligand, optionally with an aliphatic or aromatic carbo- or heterocyclic bridge, and 2 neutral or monoanionic, monodentate ligands or a bidentate ligand.  New group VIIIB transition metal complex compounds  have a bidentate bis((N-aliphatic and/or aromatic carbo- and/or heterocyclyl)-(N-heteroaryl- or -(heteroaryl)-aryl)-imine) chelate ligand, optionally with an aliphatic or aromatic carbo- or heterocyclic bridge, and 2 neutral or monoanionic, monodentate ligands or a bidentate ligand, and are of the formula (I). R1, R3  = hydrogen (H), 1-20 carbon (C) alkyl, 3-10 C cycloalkyl, 6-16 C aryl, 1-10 C alkyl-(6-16 C)-aryl, Si(R6)3, N(R6)(R7), OR6 or SR6; or  R1 and R3 together with Ca, Cb and optionally C'  =  a 5-, 6- or 7-membered aliphatic or aromatic, (un)substituted carbo- or heterocycle;  R2, R4 = 4-16 C heteroaryl or 6-16 C aryl with 4-16 C heteroaryl or 6-16 C aryl substituents in both vicinal positions to the bond with Na and Nb respectively;  R5 = H or R;  R, R6, R7  = 1-10 C alkyl, 6-16 C aryl or 1-10 C alkyl-(6-16 C)-aryl;  m = 0 or 1;  M = group VIIIB element;  T, Q = neutral or monoanionic, monodentate ligands; or  TQ  =  a diketoenolate unit or a 2 or 3 C alkylene unit with a terminal methyl ketone or linear 1-4 C alkyl ester or nitrile group;  A = non- or poorly-coordinating anion;  x, p = 0-3;  q, n = 1-3.
Patent EP-1117147-B1 (EP)
Inventor: JUDD MANO D
IPC: H01Q3/28
Filed: 2001-01-11
Granted: 2006-08-09
Abstract: An active antenna system having lightning, corona and low frequency static energy protection includes a plurality of patch antenna elements, a feed structure operatively interconnecting the patch antenna elements, and at least one conductive drain line coupled with each of the patch antenna elements. The drain lines are coupled together at a common ground connection point. <IMAGE> <IMAGE>
Patent EP-1126015-B1 (EP)
Inventor: FERGUSON JOHN A
IPC: C11D3/37
Filed: 2001-02-08
Granted: 2004-10-06
Abstract: A product for providing anti-static and scent to clothes being laundered in a dryer has a plurality of beads, or pearls, of a polymer composition impregnated with anti-static agents and perfume contained in a mesh bag. The bag and pearls are placed in a clothes dryer with clothing being dried. The anti-static agents and perfume are transmitted to the clothing during the drying cycle. The pearls are composed of a mixture of polypropylene and polyethylene. A whitening agent, such as titanium dioxide, a blowing agent and coloring can all be added to the pearls.
Patent EP-1161923-B1 (EP)
Inventor: KOLPE DIETER
IPC: A61B5/15
Filed: 2001-06-07
Granted: 2005-12-14
Abstract: The container consists of a tube (7) on which fits a closure-cap (8) which has a ledge (19) supporting it against the tube's end surface enclosing the tube-opening. A flange (18) surrounds the outer rim of the tube. A sealed stopper (9) made of perforatable and automatically re-closing material fits into the cap. The stopper has a collar (20) all round sealing the cap against the tube and positioned between the tube's end surface and the cap's ledge. The collar extends radially up to the inside (21) of the cap's flange. The perforatable part (22) of the stopper is placed inside the cylindrical lengthwise section (10) of the cap.
Patent EP-1209415-B1 (EP)
Inventor: WOOD GRAHAM
IPC: F23D14/10
Filed: 2001-10-26
Granted: 2006-03-08
Abstract: The invention describes a tubular burner consisting of a cylindrical tubular body initially open at either end into which a distributor component can be slidingly fitted. The tubular body is provided with rows of apertures over a narrow area of the uppermost surface thereof to give the burner a flame strip. The distributor is substantially the same axial length as the tubular burner body but of smaller cross-sectional dimension than said body allowing for sliding fitment of the distributor inside the burner body. In accordance with the invention, the distributor has a first tubular portion and a second extension portion which is effectively a continuation of the upper surface of said first tubular portion, and both the tubular portion and extension portion of the distributor are provided with axially aligned flanges on either side having a number of perforations. As the distributor is slid axially along the tubular burner body, the edges of the flanges engage with the inner walls of the tubular burner body and thus divide the burner body into an upper and lower chamber, the combustible air/gas mixture emerging from the tubular portion of the distributor into the lower chamber and subsequently being urged upwardly through the apertures in said flanges into the upper chamber before passing through the flame ports for combustion on the upper surface of said tubular body. The invention also relates to a distributor for use in such a burner.
Patent EP-1225026-B1 (EP)
Inventor: ROMI ROMEU
IPC: B29C45/84
Filed: 2001-12-12
Granted: 2008-07-23
Abstract: An injection moulding machine has four tie bars (12) extending through and between a movable platen (3) and a fixed platen (3a) which carry the mould halves (31). To enable the movable platen (3) to withstand the forces which arise during a moulding process, a pressure control mechanism (1) including a piston (4) is associated with each tie bar (12) and is received within a corresponding recess provided in the movable platen (3). It is also necessary to grip the tie bars during moulding and a gripping mechanism (5, 9, 11) is supported by the piston (4) such that the gripping mechanism and the piston effectively form a movable, single unit. The gripping mechanism (5, 9, 11) comprises a pair of gripping jaws (5) movable transversely and moved by way of a rotatable disc (9) which is also provided in the single unit.
Patent EP-1169407-B1 (EP)
Inventor: TRUMBLE CATHY SHAW
IPC: C09K11/77
Filed: 2001-01-10
Granted: 2003-10-29
Abstract: A luminescent nanophase binder is provided for use in UV and VUV applications. The binder promotes adherence of phosphor coatings to lamp envelopes and emits visible light under UV and VUV excitation. In a preferred embodiment, the binder comprises SiO2 nanoparticles doped with terbium or terbium and yttrium. Preferably, the nanoparticles have a particle size of less than 50 nm.
Patent EP-1264259-B1 (EP)
Inventor: FORAN JOHN ANTHONY
IPC: G06F13/00
Filed: 2001-02-12
Granted: 2007-02-28
Abstract: The present invention relates to a method of conducting a transaction in a trading system. The invention is particularly directed to a trading system where a merchant sends goods and/or services to a customer when the customer is generally located remotely from the merchant. The invention is also directed towards providing a system for carrying out such transactions. The invention is particularly directed to the carrying out of the financial transactions and is not concerned particularly with the actual method of trading.
Patent EP-1250066-B1 (EP)
Inventor: BELLINI CLAUDIO FRANCESCO
IPC: A45C5/14
Filed: 2001-01-19
Granted: 2004-07-28
Abstract: An object ( 2 ) mounted on wheels ( 4 ) has a grip device ( 1 ) of the type wherein a free end ( 10 ) of a telescopically extensible supporting structure ( 8 ) carries an integral grip portion ( 9 ) substantially parallel to an axis of rotation ( 6 ) of the wheels ( 4 ); according to the invention, the grip portion ( 9 ) has first ( 11 ) and second ( 12 ) articulating means enabling the grip portion ( 9 ) to rotate, with respect to the supporting structure ( 8 ), about two distinct axes of rotation ( 13, 14 ) perpendicular to each other; and angular locking means ( 33, 34 ) for preventing rotation of the grip portion ( 9 ) with respect to the supporting structure ( 8 ), and ensuring firm but reversible connection of the grip portion ( 9 ) to the supporting structure ( 8 ) in a predetermined mutual position. A third articulating means ( 35 ) enables the grip portion ( 9 ) to translate along one of the axes of rotation ( 13 ).
Patent EP-1263826-B1 (EP)
Inventor: HAEBERLE HANS
IPC: C09D175/04
Filed: 2001-02-14
Granted: 2005-08-24
Abstract: The use of aqueous isocyanate-free polyurethane dispersions with a solids content of >=30 wt. % and a solvent content of <=10 wt. % in formulations for crack sealing coating systems is disclosed. Said use may be in a) primer, floating screed, floor coatings, spray coatings and/or sealants, on, preferably, primed building surfaces, b) roof coatings or paints and c) sealing of open-cast or subterranean mines. According to the invention, the disclosed polyurethane dispersions are not just more environmentally-friendly and easier to use, but also give a partly improved product property to the corresponding crack sealing coating systems, such as, for example, mechanical properties (tensile strength, stretching under tension, tear elongation), UV resistance and colour stability.
Patent EP-1281038-B1 (EP)
Inventor: VARSHNEYA DEEPAK
IPC: F41G3/26
Filed: 2001-01-22
Granted: 2004-09-29
Abstract: A turret mounted gun on a shooter tank with a laser scanner transmitter in its barrel emits a laser beam upon a trigger pull. The laser beam is directed toward a target tank based upon a shooter's ranging and tracking using a standard fire control computer to provide conventional ranging and tracking. The target tank is scanned with the laser beam to measure target azimuth and target elevation with respect to a boresight of the gun of shooter tank. Optical receivers mounted on the turret of the target tank detect the laser beam and a system control unit determines the trigger pull time, target azimuth and target super elevation. The system control unit also determines a range to the target tank by comparing a set of GPS coordinates of the two tanks. Based on the target azimuth, the target super elevation, the range to the target and the time of the trigger pull, the system control unit computes an impact point relative to the target tank of a simulated ballistic shell fired from the gun of the first tank at the time of the trigger pull. Casualty assessment is made and the impact point is transmitted back to the shooter for immediate feedback.
Patent EP-1305900-B1 (EP)
Inventor: SMITH DAVID F
IPC: H04B10/293
Filed: 2001-07-06
Granted: 2006-11-15
Abstract: Optical transmission systems of the present invention include a plurality of optical amplifiers configured to provide optical amplification of one or more information carrying optical signal wavelengths. At least two of the optical amplifier are operated to provide net losses or net gains along corresponding spans, while the cumulative gain provided by the plurality of optical amplifiers substantially compensates for the cumulative loss of the spans.