baber/WOPTO huggingface dataset:
Patent NZ-551990-A (NZ)
Title: Liquid depot formulations
Inventor: THURESSON DRISTER
IPC: A61K9/70
Filed: 2005-06-06
Abstract: Disclosed is a pre-formulation comprising a low viscosity, non-liquid crystalline, mixture of: a) at least one diacyl glycerol and/or at least one tocopherol; b) at least one phosphatidylcholine; c) at least one biocompatible solvent selected from monool alcohols, ketones, esters, ethers, amides, sulphoxides and mixtures thereof; wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture, wherein the pre-fonnulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid and wherein the low viscosity, non-liquid crystalline, mixture has a viscosity of 0.1 to 5000 mPas at 20 degrees Celsius. Also disclosed is the use of said pre-formulation for the preparation of a medicament for the delivery of a bioactive agent to treat conditions e.g. bacterial infections and a process to form said pre-formulation.
Patent NZ-553435-A (NZ)
Title: Transgenic plants expressing cellulase for autohydrolysis of cellulose components and method for production of soluble sugar
Inventor: BAE HYEUN-JONG
IPC: C12N15/11
Filed: 2005-07-30
Abstract: Disclosed is a recombinant cDNA encoding a fusion protein comprising chloroplast-targeting peptide, full length cellulase and cellulose binding domain sequentially, wherein the cellulase is cellulase5 originated from Ruminococcus albus, and the cellulose binding domain is originated from Xylanase A of Clostridium stercorarium. The cDNA can be used to produce plants expressing cellulase for autohydrolysis. Methods for the production of soluble sugars comprising the induction of autohydrolysis of the cellulose are also disclosed.
Patent NZ-553910-A (NZ)
Title: Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells
Inventor: BRAHMBHATT HIMANSHU
IPC: C12N15/113
Filed: 2005-08-25
Abstract: Provided is a composition comprising (a) an intact minicell that contains a functional nucleic acid molecule or a plasmid comprising a segment that encodes a functional nucleic acid molecule, (b) an intact minicell that contains a small molecule drug or peptide drug, and (c) a pharmaceutically acceptable carrier for each of (a) and (b), where said functional nucleic acid molecule targets the transcript of a protein that contributes to drug resistance, apoptosis resistance, or neoplasticity. Further provided is thus use of a plurality of said minicells in the preparation of a medicament for use in treating a disease of modifying a trait.
Patent NZ-556383-A (NZ)
Title: Vessel cap and system for manufacturing the same
Inventor: RHO HEE KWON
IPC: B65D51/22
Filed: 2005-12-07
Abstract: A liquid containing bottle 10 is sealed with a cap 152 with a pressing plate 160 at the outlet and a seal 20 placed below the cap. The pressing plate 160 has a circumferential cutter 162 and a supporting rod 176 with a bendable hook 178 on its lower surface. An elastic section 166 joins the pressing plate 160 to the rest of the cap so that the pressing plate 160 can be moved up and down. When the pressing plate 160 is pressed down and the cap turned the cutter 162 will cut the seal 20 along its circumference. At the same time, the hook will penetrate the seal 20 and the hook protrusions 178 will be bent upwards capturing the seal 20. This arrangement has the advantage that the seal 20 is removed with the cap when the bottle is opened.
Patent NZ-573139-A (NZ)
Title: Cassette for needleless syringe with sealed chamber caused by plastic deformation against membrane
Inventor: BATES NIGEL ROBERT
IPC: A61M5/30
Filed: 2007-06-04
Abstract: A method is disclosed of producing a particle cassette for a needleless syringe device which alleviates problems of providing a chamber for the confinement of particles which is hermetically sealed from the environment. A predetermined force is applied in the longitudinal direction to push first and second cassette parts together so as to cause plastic deformation of a portion of the first cassette part so as to create said hermetically sealed chamber. The cassette parts are preferably made of PETG and have bonded thereto rupturable membranes preferably made of PET. The sealing is preferably achieved at the end of a protrusion on the first cassette part which is tapered and which interacts with the membrane of the second cassette part.
Patent NZ-576194-A (NZ)
Title: Methods and compositions for treatment of bone defects with placental cell populations
Inventor: EDINGER JAMES W
IPC: C12N5/077
Filed: 2007-10-23
Abstract: Disclosed is the use of a population of isolated adherent placental cells in the manufacture of a medicament for the treatment of a bone defect in a human individual, wherein the bone defect is an osteolytic lesion associated with cancer, a bone fracture, or a spine in need of fusion, wherein said placental stem cells are present in an amount sufficient to treat said bone defect; wherein said population is CD105+, CD200+, CD10+, and CD34-, and wherein said medicament is implantable or injectable. The stem cells are not human totipotent cells.
Patent NZ-579707-A (NZ)
Title: Allergen-free, protein-free or at least dairy free powdered nutritional compositions and the use thereof in food products
Inventor: VAN SEEVENTER PAUL BASTIAAN
IPC: A23L33/20
Filed: 2008-03-12
Abstract: Provided is spray-dried allergen-free composition comprising: (i) from 10-80 wt.% of an oxidation sensitive active ingredient; in a matrix comprised of (ii) mannitol; (iii) reducing sugars; the weight ratio of mannitol/reducing sugars being in the range of 2:1 to 1:40; (iv) emulsifying starch; (v) low molecular weight emulsifiers; and (vi) a metal chelator.
Patent NZ-583157-A (NZ)
Title: Treatment of solid cancers with angeloyl substituted ingenanes
Inventor: OGBOURNE STEVEN MARTIN
IPC: A61K31/22
Filed: 2005-12-02
Abstract: Disclosed is the use of an angeloyl substituted ingenane derived from a plant of the Euphorbiaceae family or botanical or horticultural relatives of such plants in the manufacture of a medicament for treating a secondary cancer wherein said medicament is formulated in a composition for topical and/or intra tumoral administration to a primary cancer on the skin.
Patent NZ-583689-A (NZ)
Title: F1f0-atpase inhibitors and related methods
Inventor: NEY GINA
IPC: C07C233/02
Filed: 2008-09-11
Abstract: Disclosed is a compound represented by Formula I including salts thereof, wherein: R1 is imidazolidonyl or a heteroaryl containing at least 1 ring nitrogen atom; R2 and R3 represent independently for each occurrence hydrogen or (C1-C4)alkyl; R5 represents independently for each occurrence hydrogen, halogen, alkyl, haloalkyl, aryl, heteroaryl, -NO2, -CN, -C(O)aryl, -C(O)heteroaryl, -C(O)N(R2)aryl, or -C( O)N (R2)heteroaryl; N is 0, 1, 2, 3 or 4 m represents independently for each occurrence 1 or 2; and the stereochemical configuration at a stereocenter in a compound represented by Formula I is R, S, or a mixture thereof.
Patent NZ-584752-A (NZ)
Title: Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives
Inventor: WANG PEIYUAN
IPC: C07H21/00
Filed: 2005-07-21
Abstract: Disclosed is a method for the preparation of a 2'-deoxy-2'-fluoro-2'-C-methyl-beta-D-ribofuranosyl nucleoside of the pictured formula, where Base is one of the two pictured groups and the other substituents are as defined in the specification.
Patent NZ-591598-A (NZ)
Title: Particle-modified fluoropolymers for imparting surface properties to substrates wherein the particle-modified fluoropolymers impart oil repellency, water repellency and soil resistance properties
Inventor: BROWN GERALD ORONDE
IPC: C08G18/28
Filed: 2009-11-11
Abstract: Disclosed are compositions comprising an aqueous solution or dispersion of at least one polyurethane having at least one urea linkage prepared by: (i) reacting (a) at least one diisocyanate, polyisocyanate, or mixture thereof, having isocyanate groups, and (b) at least one fluorinated compound selected from the formula (I): Rf1-L-X (I) wherein: Rf1 is a monovalent, partially or fully fluorinated, linear or branched, radical having 2 to 100 carbon atoms, L is a bond or a linear or branched divalent linking group having 1 to about 20 carbon atoms, X is OH, N(R1)H, or SH wherein R1 is H or C1 to C6 alkyl; and thereafter (ii) reacting with (c) water and (d) an isocyanate-reactive fluorinated particulate component, wherein the fluorinated particulate component has an average particle size of about 10 to about 500 nm and comprises 1) inorganic oxides of Si, Ti, Zn, Mn, AI, and Zr; 2) a colloidal particle made by hydrolysis of an alkoxy silane, chlorosilane, metal alkoxide, or metal halide; or 3) a fumed silica.
Patent NZ-594238-A (NZ)
Title: Dual field-of-view optical imaging system with dual focus lens, and with axially movable detector
Inventor: CARON HUBERT
IPC: G02B1/11
Filed: 2010-02-19
Abstract: A dual field-of-view optical imaging system is provided for obtaining two images of a scene, each image having a different field of view. The dual field-of-view optical imaging system includes a frontal dual focus lens, the dual focus lens having a central zone of focal length fi producing a wide field-of-view image at a first focal plane and a peripheral zone of focal length I2 greater than fi producing a narrow field-of-view image at a second focal plane; and a detector for detecting and acquiring the wide field-of-view image and the narrow field-of-view image, the detector being movable along an optical path for selective positioning at the first focal plane or the second focal plane.
Patent NZ-597209-A (NZ)
Title: Tubular element of a fall pipe, fall pipe and method for assembling the fall pipe
Inventor: GABRIEL JAN
IPC: F16L37/244
Filed: 2010-06-11
Abstract: 597209 Tubular element (1a, 1b) of a fall pipe used for the purpose of depositing materials underwater from a fall pipe vessel. The element (1a, 1b) comprises a male (20) and a female (10) coupling part for coupling to another element of the same form, the coupling parts (10, 20) are provided on respectively an outer periphery and inner periphery of the element (1a, 1b) with at least two annular flanges which lie at a mutual axial distance and are divided in peripheral direction into segments (22a, 23a, 12a, 13a) which leave recesses (22b, 23b, 12b, 13b) clear there between. The segments (22a, 12a) of an upper annular flange are arranged offset relative to the segments (24a, 13a) of a lower annular flange. For coupling, segments (22a, 23a) of a male coupling part (20) are placed through recesses (12b, 13b) of a female coupling part (10) and are slid by rotation under segments (12a, 13a) of the female coupling part (10) at least twice.
Patent NZ-597807-A (NZ)
Title: Assessment of animals and carcasses
Inventor: TURNER IAN FRANK
IPC: A22B5/00
Filed: 2010-06-29
Abstract: 597807 Disclosed are methods of assessing and determining the composition of an animals or carcasses. The methods include projecting at least one light stripe onto the animal or carcass by non-uniformly illuminating the animal or carcass and detecting at least part of at least one projected light stripe using a detector. Anatomical features of the animal or carcass are used to generate reference data or an assessment algorithm, which may be used to assess the body composition of the animal or carcass. Apparatuses and computer systems for performing the method are also disclosed.
Patent NZ-600575-A (NZ)
Title: Re-use of surfactant-containing fluids
Inventor: HUANG TIANPING
IPC: B01D15/00
Filed: 2010-12-21
Abstract: 600575 Disclosed is a method for filtering a fluid comprising water, at least one surfactant and fine solids, the method comprising contacting the fluid with substrate particles bearing comparatively smaller particulate additives thereon, thereby removing at least a portion of the fine solids therefrom to give a filtered fluid containing the surfactant, where the particulate additives are present in an amount effective to remove at least a portion of the fine solids from the fluid, and the filtered fluid is re-used.
Patent NZ-601454-A (NZ)
Title: Process for providing a filled canister for an inhaler
Inventor: BERRY SIMON CHRISTOPHER
IPC: A61K9/00
Filed: 2011-02-09
Abstract: 601454 A process for providing a filled canister (138) for an inhaler with has not been purged prior to filling is disclosed. In particular it is a process for supplying a canister (138) and filling the canister (138) with components of a medicament, which canister (138) is suitable for use in a pressurised metered dose inhaler, preferably a breath-actuate inhaler. The process comprises providing a canister (138) that is substantially filled with air at ambient conditions and sealing the opening of the canister (138), for example with a metering valve (134). A filling device dispenses a pressurised liquid and/or gas into the sealed, air-filled canister (138) through the metering valve (134). The pressurised liquid and/or gas comprises at least a propellant. The sealed, air-filled canister (138) is substantially devoid of propellant prior to the step of dispensing the pressurised liquid and/or gas. Thereafter the sealed canister (138) is substantially filled with at least some propellant and some air. Preferably the sealed canister (138) also contains a medicament. In the art, pressure-filled canisters are purged with propellant immediately before sealing to remove the air. The present process excludes the purging step and the sealed canisters (138) contain air and no propellant prior when sealed which prevents unnecessary release of the propellant into the atmosphere.
Patent NZ-603076-A (NZ)
Title: Suspension and cake composition containing carbostyril derivative and silicone oil and/or silicone oil derivative
Inventor: HIRAOKA SHOGO
IPC: A61K31/4709
Filed: 2011-08-19
Abstract: The disclosure relates to a method to form a suspension of aripiprazole and/or a derivative (themselves both a derivative of carbostyril) and a silicone oil and/or silicone oil derivative. The aripiprazole and/or derivative are initially in the form of particles between the size of 0.1 µm and 200 µm. The ratio of silicone oil and/or silicone oil derivative to aripiprazole and/or derivative in the suspension is 0.001 – 0.2:100 weight parts. Aripiprazole contains a 1H-quinolin-2-one and a piperazine moiety and the derivative also contains a benzothiophene moiety. The disclosure also relates to the suspension the method refers to and a cake composition. The method in this disclosure is suitable for forming pharmaceutical compositions that are less likely to agglomerate and are therefore more effective.
Patent NZ-607376-A (NZ)
Title: Braking devices and methods for use in drilling operations
Inventor: DRENTH CHRISTOPHER L
IPC: E21B25/02
Filed: 2009-04-22
Abstract: A braking device (200) is disclosed for stopping a core barrel assembly in a drill string in a borehole. The braking device comprises a brake retainer (230) with a plurality of brake connector openings (235), a body member (220) with a tapered surface (222) and a plurality of brake elements (234). The brake elements (234) are positioned at least partially within the brake connector openings (235). Relative movement of the body member (220) towards a first end of the brake retainer (230) moves the plurality of brake elements (234) outward and into contact with the drill string.
Patent NZ-614551-A (NZ)
Title: 6,7-dihydro-pyrazolo[1,5-a]pyrazin-4-ylamine derivatives useful as inhibitors of beta-secretase (bace)
Inventor: TRABANCO-SUÁREZ ANDRÉS AVELINO
IPC: C07D487/04
Filed: 2012-02-29
Abstract: Disclosed herein are 6,7-dihydro-pyrazolo[1,5-a]pyrazin-4-yl-amine derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACEl, Asp2, or memapsin2. Also disclosed are pharmaceutical compositions comprising such compounds, processes for preparing such compounds and compositions, and the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer’s disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down’s syndrome, dementia associated with stroke, dementia associated with Parkinson’s disease or dementia associated with beta-amyloid. In one embodiment the compound is (R)-5-methoxy-pyrazine-2-carboxylic acid [3-(4-amino-3-fluoro-2, 6-dimethyl-6,7-dihydro-pyrazolo[1, 5-a]pyrazin-6-yl)-4-fluoro-phenyl]amide.
Patent NZ-616152-A (NZ)
Title: Oil absorbent composition
Inventor: DE LEIJ FRANCISCUS ANTONIUS ANNA MARIA
IPC: C09K3/32
Filed: 2012-03-28
Abstract: Disclosed herein is a method of preparing an oil absorbent composition. The method comprises heating and then de-mineralising a precursor plant material under conditions suitable to produce an oil absorbent composition comprising charcoal. The disclosure extends to oil absorbent compositions per se, such as charcoal-based compositions, and to various uses of the compositions for efficiently and rapidly absorbing spilled oil, for example from water surfaces, or from bituminous sands.
Patent NZ-617822-A (NZ)
Title: Microwave container
Inventor: CHEUNG CHAK HONG GARY
IPC: B65D85/72
Filed: 2013-11-15
Abstract: Disclosed is a microwave container (10). The disclosure notes that current mechanisms for releasing pressure from a microwavable container are complicated in structure. The container (10) includes a simpler vent opening (36) to allow the release of pressure and vapour formed inside the container (10) during cooking or heating up of food in a microwave. The microwave container (10) comprises a container body (12); a lid (14) and a flap (50). The container body (12) includes a bottom wall (20) and a sidewall (22) extending from a periphery of the bottom wall (20) and ending at a rim. The lid (14) includes a top wall (30) and a sidewall (32) extending downwardly from a periphery of the top wall (30) and ending at a brim (34). The lid (14) is formed with a vent opening (36). The flap (50) includes proximal (52) and distal (54) portions. The proximal portion (52) is hingedly connected to the brim (34) of the lid (14) by a hinge (58). The distal portion (54) extends outwardly and is formed with a plug (56). The flap (50) is movable from a free hanging position where the flap (50) hangs freely from the brim (34) of the lid (14) into a closed position where the flap (50) is flipped about the hinge (58) over a side of the lid (14). In the closed position, the plug (56) is plugged into the vent opening (36).
Patent NZ-629701-A (NZ)
Title: Target detection and signal amplification
Inventor: TODD ALISON VELYIAN
IPC: C12Q1/68
Filed: 2013-06-18
Abstract: Discloses a composition comprising: (i) a first molecular complex comprising: a first catalytic nucleic acid enzyme; or a catalytic portion thereof; or a nucleotide sequence complementary to the enzyme or the catalytic portion thereof; hybridised to a first blocker oligonucleotide (BL) by complementary base pairing, wherein at least one: nucleotide, and catalytic core nucleotide of the first enzyme or the catalytic portion thereof, or nucleotides of the sequence that is complementary to a catalytic core is hybridised to the first BL, and the first catalytic nucleic acid enzyme is not an aptazyme; (ii) a nucleic acid substrate capable of catalytic modification by the first catalytic nucleic acid. Also disclosed are kits and methods of detecting molecules using related molecules.
Patent NZ-630778-A (NZ)
Title: Wearing part arrangement for plough share
Inventor: SKJAEVELAND MAGNE
IPC: A01B15/06
Filed: 2013-05-22
Abstract: A wearing-part arrangement for a leading edge (21) of a plough body (1) is described. A plough point (3) is releasably attached to the plough body (1). The plough point (3) is mirror-symmetrical around the longitudinal axis (SA) of the plough point (3) and is provided with a pointed front portion (31) and oblique faces (311, 312). A side edge of the plow point (3) projects beyond the edge (22) of the plough share (2) when the plough is used in a ploughing direction (TD).
Patent NZ-700732-A (NZ)
Title: Pharmaceutical compositions comprising hydromorphone and naloxone
Inventor: HAYES GEOFFREY GERARD
IPC: A61P25/04
Filed: 2011-05-10
Abstract: Disclosed herein is an oral prolonged release pharmaceutical composition comprising at least: at least one prolonged release material, preferably selected from the group comprising hydrophobic or hydrophilic polymers, protein-derived material, gums, substituted or unsubstituted hydrocarbons, digestible carbohydrates, fatty acids, fatty alcohols, glyceryl esters of fatty acids, natural and synthetic oils and natural and synthetic waxes; at least hydromorphone or a pharmaceutically acceptable salt or derivative thereof and naloxone or a pharmaceutically acceptable salt or derivative thereof with hydromorphone or a pharmaceutically acceptable salt or derivative thereof and naloxone or a pharmaceutically acceptable salt or derivative thereof being present in the pharmaceutical composition in a weight ratio of about 2: 1, about 1:1, about 1:2 or about 1:3.
Patent NZ-705430-A (NZ)
Title: Method and control device for a wind turbine, and computer program product, digital storage medium and wind turbine
Inventor: BAUMGÄRTEL CHRISTIAN
IPC: F03D7/04
Filed: 2013-06-20
Abstract: The invention relates to a method for operating a wind turbine in which method the rotor is brought to a standstill and locked, having the steps: braking the rotor; positioning the rotor in a standstill position; immobilizing the rotor in the standstill position. It is provided according to the invention that a final position is predefined, the rotor is braked in controlled fashion to a standstill position assigned to the final position, and for the positioning for the predefined final position, the rotor is automatically braked until it comes to a standstill in the standstill position, and for the immobilization in the standstill position, a mechanical immobilizing device is engaged, in particular automatically.
Patent NZ-708144-A (NZ)
Title: Recombinant adenoviruses and use thereof
Inventor: BAROUCH DAN
IPC: C12N15/861
Filed: 2013-11-15
Abstract: The present invention relates to recombinant adenoviruses and vectors thereof. In particular, the adenoviruses are novel simian adenoviruses having a low seroprevalence and high immunogenicity relative to other adenoviruses and vectors thereof. The invention also provides methods for production of the adenoviruses and for the treatment of diseases by administering the adenoviral vector(s) to a subject (e.g., a human).
Patent NZ-709693-A (NZ)
Title: Wind turbine and method for operating a wind turbine
Inventor: BRENNER ALBRECHT
IPC: F03D7/02
Filed: 2013-12-05
Abstract: The invention relates to a method for operating a wind turbine (1) with a rotor (6) having rotor blades (8) with a substantially horizontal axis of rotation for producing electrical energy from wind energy. According to the invention, the wind turbine (1) is oriented such that the azimuth position of the wind turbine (1) deviates from an alignment into the wind (16) by an azimuth adjustment angle, and/or the blade angle of the rotor blades (8) is adjusted in terms of the rotation cycle thereof such that dynamic loads caused by a height profile of the wind (16) are reduced. In particular, a profile operating point provides a profile azimuth position that deviates by the azimuth adjustment angle from a normal alignment, and a profile blade angle that deviates by a blade adjustment angle from a normal blade angle, wherein a weighting is performed between the azimuth adjustment angle and the blade adjustment angle.