baber/WOPTO huggingface dataset:
Patent CA-2995582-A1 (CA)
Inventor: LIU YANG
IPC: A61P37/00
Filed: 2016-08-18
Abstract: A method of preventing the development of GvHD or reducing the severity of GvHD in a mammalian subject receiving an allogeneic hematopoietic stem cell (HSC) transplant includes administering to the subject a pharmaceutical composition comprising an active agent that inhibits the biological activity or expression of hypoxia-inducible factor -la (HIF-la) or hypoxia-inducible factor -2a (HIF-2a), wherein the active agent is administered in an amount effective for preventing or reducing the severity GvHD in the subject.
Patent CA-2999376-A1 (CA)
Title: Wind turbine rotor blade and wind turbine system
Inventor: SPIETH FALK
IPC: F03D1/06
Filed: 2016-09-26
Abstract: The invention relates to a rotor blade of a wind turbine system. The rotor blade comprises a blade root for connecting the rotor blade to a rotor hub, an inner blade section which extends from the blade root in the direction of the longitudinal axis of the rotor blade, at least one trailing edge segment section of a trailing edge segment for increasing the profile depth of the rotor blade at the blade root, and at least one first and second securing section for securing the at least one trailing edge segment section of the trailing edge segment to the inner blade section. The first securing section is arranged at a specified distance from the second securing section in the direction of the longitudinal axis of the rotor blade, and the at least one trailing edge segment section of the trailing edge segment is secured to the inner blade section such that loads occurring on the inner blade section are transmitted onto the at least one trailing edge segment section of the trailing edge segment at points via the first and the second securing section.
Patent CA-3004581-A1 (CA)
Inventor: STILLER ALFRED
IPC: C01B32/942
Filed: 2014-03-14
Abstract: The disclosure provides for methods of oxidizing carbide anions, or negative ions, from salt like carbides at temperatures from about 150°C to about 750°C. In another aspect, the disclosure provides for reactions with intermediate transition metal carbides. In yet another aspect, the disclosure provides for a system of reactions where salt-like carbide anions and intermediate carbide anions are oxidized to produce pure carbon of various allotropes.
Patent CA-3004587-A1 (CA)
Inventor: COULON RICK
IPC: A61K31/216
Filed: 2016-10-24
Abstract: Hydrocinnamate compounds that exhibit proteasome modulation activity, and in particular, proteasome inhibitory activity, can be used to topically or systemically treat ocular disorders associated with proteasome activity. The hydrocinnamate compounds can be applied to the eye, in any of a variety of ocular formulations, to treat ocular disorders, such as ocular rosacea, diabetic retinopathy, macular degeneration, and dry eye. The hydrocinnamate compounds can also be administered systemically to treat ocular disorders.
Patent CA-3005753-A1 (CA)
Title: Procede de production de cellules t bi-specifiques pour une utilisation en immunotherapie anticancereuse
Inventor: CUI WEIGUO
IPC: A61K39/00
Filed: 2016-11-18
Abstract: La présente invention concerne des lymphocytes autologues bi-spécifiques, leurs procédés de production et leurs utilisations dans le traitement des tumeurs. En particulier, l'invention concerne des procédés de production de lymphocytes autologues bi-spécifiques comprenant un récepteur endogène pour au moins un antigène associé à la tumeur et un récepteur exogène pour un antigène fort.
Patent CA-3006008-A1 (CA)
Inventor: SAYGILI ALI MURAT
IPC: A24F40/485
Filed: 2017-01-25
Abstract: There is provided a cartridge assembly (4) for use in an aerosol-generating system, the cartridge assembly (4) comprising a cartridge (2) and a mouthpiece (26). The cartridge (2) comprises a cartridge body (6) and a cartridge cover (8), the cartridge body (6) having a first side defining a first recess (10) and a second side defining a second recess (12). The cartridge cover (8) comprises a cartridge cover cavity in which the cartridge body (6) is slidably received and an actuation aperture (24) for receiving an actuation portion of an aerosol-generating device. The cartridge assembly (4) is configured so that, when an actuation portion of an aerosol-generating device is received against the cartridge body (6) through the actuation aperture (24), the cartridge body (6) is slidable within the cartridge cover cavity from a first position to a second position. In the first position, airflow through the first and second recesses (10, 12) is prevented. In the second position, airflow through the first and second recesses (10, 12) is enabled.
Patent CA-3006464-A1 (CA)
Title: Materiaux de reference cellulaires multiplex
Inventor: HUANG CATHERINE
IPC: C12Q1/68
Filed: 2016-08-25
Abstract: L'invention concerne des acides nucléiques comprenant une pluralité de séquences nucléotidiques, chaque séquence nucléotidique correspondant à un génotype. Les acides nucléiques sont utiles pour le développement de matériaux de référence biologiques comprenant un certain nombre de génotypes différents.
Patent CA-3007214-A1 (CA)
Title: Emm-28, nouveau materiau cristallin synthetique, sa preparation et son utilisation
Inventor: SCHMITT KIRK D
IPC: C01B39/48
Filed: 2016-11-23
Abstract: L'invention concerne un nouveau matériau cristallin synthétique, l'EMM-28, pouvant être synthétisé en présence d'un agent d'orientation de structure organique (Q) choisi parmi une ou plusieurs des indications suivantes : Formule (I), (II). L'EMM-28 peut être utilisé dans des réactions de transformation de composés organiques et des procédés de sorption.
Patent CA-3007641-A1 (CA)
Inventor: LISMAN JOHN
IPC: A61K31/105
Filed: 2016-12-09
Abstract: The present invention relates to the use of DBH inhibitors (e.g., disulfiram and Nepicastat), and pharmaceutical compositions thereof, for treating subjects with certain types of memory loss, for instance memory loss associated with a neurodegenerative disease, disorder, or condition, such as Alzheimer's Disease.
Patent CA-3018198-A1 (CA)
Title: Systeme d'elimination de dechets ayant un ou plusieurs couvercles
Inventor: CHENVAINU ALEXANDER
IPC: B65F1/14
Filed: 2017-07-07
Abstract: L'invention concerne un couvercle de logement (70), pour un dispositif d'élimination de déchets (12), qui comporte un corps ayant une extrémité supérieure et une extrémité inférieure, un élément de fixation longitudinal généralement perpendiculaire à l'extrémité supérieure et/ou à l'extrémité inférieure, l'élément de fixation longitudinal reliant le corps pour former le couvercle de sorte que le couvercle est généralement continu, un élément de fixation d'extrémité supérieure positionné à proximité de l'extrémité supérieure, un élément de fixation d'extrémité inférieure positionné à proximité de l'extrémité inférieure, une ouverture (92) positionnée entre l'extrémité supérieure et l'extrémité inférieure, l'ouverture (92) permettant l'accès au dispositif d'élimination de déchets (12), et un élément de fixation d'ouverture positionné à proximité de l'ouverture (92), le corps étant un matériau étirable.
Patent CA-3018207-A1 (CA)
Inventor: BAUERLE PASCAL
IPC: F21V33/00
Filed: 2017-03-23
Abstract: The present invention concerns a glazing panel (1), and in particular a vehicle glazing panel, comprising a laminated glazed element (2) comprising an external glass sheet (3), an internal glass sheet (5) and an insert sheet made from plastic material (4) positioned between said two glass sheets and comprising at least one light-emitting diode (20) located under a peripheral edge of said insert surface (32) of said external glass sheet (3), characterised in that the emitting surface (21) of the light-emitting diode (20) is located facing at least a part of said edge (51) of said internal glass sheet (5) and in that it comprises a profiled bead (6) comprising an outer lip (63), an inner lip (65) and a body (64), said body (64) being set apart from said emitting surface (21) of said light-emitting diode (20) and not in contact with same.
Patent CA-3018829-A1 (CA)
Title: Hub bearing system
Inventor: BREEZE IAN
IPC: F16C33/02
Filed: 2018-09-27
Abstract: There is disclosed a hub bearing assembly comprising: a housing having an internal cylindrical opening; an annular bearing accommodated within the cylindrical opening of the housing; and a cylindrical pin accommodated within the annular bearing, wherein the housing and the cylindrical pin rotate relative to each other.
Patent CA-3019920-A1 (CA)
Inventor: JAFFARI JAVID
IPC: G06F1/32
Filed: 2017-04-13
Abstract: La présente invention concerne des circuits de gestion de chutes de tension d'alimentation permettant de réduire ou d'éviter les chutes de tension d'alimentation. Un circuit de gestion de chutes de tension d'alimentation comprend un circuit d'interruption configuré pour recevoir des signaux d'événement générés par un circuit fonctionnel. Les signaux d'événement correspondent à un événement opérationnel qui se produit dans le circuit fonctionnel et augmente la demande de courant de charge à une alimentation électrique mettant sous tension le circuit fonctionnel, ce qui provoque une chute de tension d'alimentation. Le circuit d'interruption est configuré pour générer un signal d'interruption en réponse au signal d'événement reçu. La mémoire comprend une table de fréquence d'événement opérationnelle ayant des entrées avec une fréquence cible correspondant à un événement opérationnel. Le fonctionnement du circuit fonctionnel à une fréquence cible réduit la demande de courant de charge sur l'alimentation électrique, et la chute de tension d'alimentation. Un circuit de commande d'horloge est configuré pour recevoir un signal d'interruption, accéder à une mémoire pour déterminer la fréquence cible, et générer un signal de réglage de fréquence d'horloge pour amener le générateur d'horloge à s'ajuster à la fréquence cible.
Patent CA-3020166-A1 (CA)
Inventor: LUKE WAYNE D
IPC: A61K31/28
Filed: 2017-04-05
Abstract: Pharmaceutical compositions of phosphaplatin compounds, in particular buffered stable liquid formulations of pyrodach-2 ready for use in the treatment of various cancers, and methods of preparation are disclosed.
Patent CA-3020501-A1 (CA)
Inventor: Ruland Scott
IPC: G01N33/497
Filed: 2018-10-10
Abstract: Embodiments include breath intoxicant monitoring systems and methods of operating a breath intoxicant monitoring system. In an embodiment, a breath intoxicant monitoring system, includes a first detection element, a second detection element, and a control module. The first detection element can be operable to detect a level of an intoxicant in a user's breath and to provide a continuous signal indicating the level of intoxicant. The second detection element can be operable to detect a level of the intoxicant. The second detection element includes a different type of element than the first detection element. The second detection element can have greater accuracy than the first detection element. The control module to selectively operate the second detection element based on the signal received from the first detection element, and to indicate whether the level of intoxicant in the user's breath exceeds a threshold.  Other embodiments are also included herein.
Patent CA-3021261-A1 (CA)
Title: Rope tension and release system
Inventor: PRIDHAM KENNETH
IPC: F16G11/00
Filed: 2018-10-18
Abstract: The rope tension and release system allows animal owners to quickly tie-off their horses and other animals to a secured location. This is done by means of using two toothed plates to clamp onto the rope. This design allows the clamped rope to be slowly let out to calm the animal down. This alternative is healthier for the animals and is designed to reduce injuries the animal may inflict on itself and others. The plates are held in compression by a torsion element with the proper torque rating to allow rope slippage to occur. The mounting plate can be mounted onto various adapters or surfaces depending on the application and location. To secure the rope, an individual must pull on the front-plate and insert the rope. Upon the release of the front-plate, the teeth on the plates will grip into the rope and the system will be active.
Patent CA-3021425-A1 (CA)
Title: Manganese complexes with substituted bisphosphonates useful as imaging and therapeutic agents
Inventor: LASCOLA CHRISTOPHER DAVID
IPC: A61K49/08
Filed: 2016-10-26
Abstract: Provided herein is a compound useful as a magnetic resonance imaging (MRI) contrast agent and a therapeutic agent, said compound having a structure represented by: Y  X  Z wherein, X is Mn(II), and Y and Z are each independently a bisphosphonate coupled to one or more therapeutic agents. Methods of use of the compound for MRI imaging and treatment for cancer or a microbial infection are also provided.
Patent CA-3021756-A1 (CA)
Inventor: POVEY THOMAS
IPC: G05D7/03
Filed: 2017-04-25
Abstract: A device for controlling the flow of a fluid through a conduit from an upstream side of the device to a downstream side of the device. The device includes a valve aperture (30), a cylindrical mounting member (24) on the downstream side of the valve aperture, a valve member (26) on the outside of the cylindrical mounting member that moves reciprocally to open and close the valve aperture, a control volume (44) defined between the cylindrical mounting member and the valve member, an arrangement (8) for introducing a control pressure into the control volume, and a seal (34) between the outer surface of the cylindrical mounting member and the inner surface of the valve member that substantially seals the control volume. The valve member is acted on by the pressure of the upstream side (PI) and the control pressure (P4) so as to be moved by the difference between these pressures.
Patent CA-3025702-A1 (CA)
Title: Stable cannabinoid formulations
Inventor: VANGARA KIRAN KUMAR
IPC: A01N65/00
Filed: 2017-04-27
Abstract: The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.
Patent CA-3026869-A1 (CA)
Inventor: TRUE WILLARD R
IPC: G06F21/84
Filed: 2018-12-07
Abstract: A method in a high integrity device for verifying the integrity, continuity, and availability (ICA) of information displayed on an uncertified display is provided. The method comprises creating, on the high integrity device, application data for display on an uncertified display device; transmitting the application data to the uncertified display device; receiving, at the high integrity device from an optical sensing device, a captured image of the display; determining, at the high integrity device, an expected display image to be displayed on the uncertified display device; comparing, at the high integrity device, the captured image of the display to the expected display image; identifying, at the high integrity device, a loss of ICA if one or more frames in the captured image fails the comparison with the expected display image; and causing the annunciation of a message indicating the loss of ICA when a loss of ICA is identified.
Patent CA-3027282-A1 (CA)
Title: Automated door slider assembly
Inventor: MIRONCHUK VADYM
IPC: E05F15/652
Filed: 2018-12-12
Abstract: An automated door slider assembly is disclosed. The assembly includes a motor unit having a body mounted to a top edge of a stationary support panel and a drive screw bracket installed at an opposite end of the motor unit and mounted to the top edge of the stationary support panel. A longitudinal drive screw having first and second ends is connected to the motor unit at the first end and the drive screw bracket at the second end. A drive screw nut is installed onto the drive screw such that the drive screw nut moves along an axis of the drive screw when the drive screw is rotated by the motor unit during operation. A door panel bracket is attached to a slide panel that moves through the door panel bracket as the drive screw nut moves along the axis of the drive screw when the drive screw is rotated by the motor unit during operation. A  drive screw bushing houses the drive screw nut such that the door panel bracket is attached to the drive screw bushing and is moved along the axis of the drive screw with the drive screw nut such that the slide panel is moved between open and closed positions during operation.
Patent CA-3027649-A1 (CA)
Inventor: BORDES PHILIPPE
IPC: H04N19/139
Filed: 2017-06-27
Abstract: Selon l'invention, dans un mode de réalisation particulier, un décodeur vidéo peut décoder un prédicteur de vecteur de mouvement initial à partir du train de bits pour un bloc courant, et effectuer une recherche de mouvement dans une petite fenêtre de recherche pour affiner le prédicteur de vecteur de mouvement initial. Le vecteur de mouvement initial peut être arrondi avant affinement. L'affinement de mouvement peut être basé sur une mesure de discontinuité entre des pixels d'un bloc courant et des pixels d'un bloc adjacent, et peut également être basé sur des gradients entre le bloc courant et des blocs adjacents. Le vecteur de mouvement pour le bloc courant est ensuite décodé sur la base du prédicteur de vecteur de mouvement affiné, et de la différence de vecteur de mouvement le cas échéant. L'affinement du mouvement peut également être effectué directement sur le vecteur de mouvement pour le bloc courant. L'affinement du mouvement permet au décodeur d'augmenter la résolution de mouvement. Un codeur vidéo correspondant peut choisir d'utiliser un affinement de mouvement fondé sur des décisions de codeur.
Patent CA-3027871-A1 (CA)
Inventor: MCVICAR MARTIN
IPC: B62B3/06
Filed: 2012-09-04
Abstract: A motorised truck with tiller such as a pallet carrier or forklift truck has a tiller- controlled steerable wheel 14 which is steered by a motor having an associated steering motor controller. The steering motor controller in a normal mode of operation detects movement of the tiller as it is rotated relative to the chassis to steer the truck, and outputs control signals to cause the steering motor to steer the wheel such that it follows the tiller angle with a fixed, predetermined offset (which may be zero or non-zero). In a realignment mode of operation, the controller can change the predetermined angular offset, and the controller can preferably align the wheel with the tiller or with an axis of the chassis. The truck can be manoeuvred more easily into and out of tight spaces with the operator and tiller offset to the side of the truck. The tiller can also be offset manually from the wheel by decoupling the tiller and wheel, and thereby changing the predetermined offset for subsequent operation.
Patent CA-3028407-A1 (CA)
Title: Laser-assisted machining (lam) of non-monolithic composite bone material
Inventor: DAHOTRE NARENDRA
IPC: A61B18/20
Filed: 2017-06-19
Abstract: An apparatus and method for laser-assisted machining (LAM) of non-monolithic composite bone material is described. A high intensity focused laser beam conducts bone material removal in extremely short time duration without causing any thermal (necrosis) and mechanical damage to the material surrounding the bone-laser interaction region. A computer associated with the apparatus for machining bone preferably employs a Multiphysics computational modeling approach which takes into account physical phenomena such as heat transfer, fluid flow, convection mixing, and surface tension when determining bone target volume, calculating material properties of the multicomponent and multicomposition composite bone material, determining parameters for the laser-assisted machining based on the material properties, and performing the laser-assisted cutting/shaping/machining of bone.
Patent CA-3028576-A1 (CA)
Title: Radiation imaging apparatus
Inventor: MELLOR MATTHEW PAUL
IPC: G01T1/169
Filed: 2017-06-30
Abstract: A radiation imaging apparatus comprising: an optical imaging device configured to image real world structures; a position and orientation detector configured to determine an instantaneous position and orientation of the radiation imaging apparatus in six degrees of freedom relative to the real world structures as a fixed frame of reference; a radiation detector configured to detect ionising radiation; a radiation source determination section configured to determine a distribution of radiation sources based on data of the ionising radiation detected by the radiation detector combined with data of the position and orientation of the radiation imaging apparatus relative to the real world structures; and an image generator configured to generate data for a combined image comprising an optical image of the real world structures imaged by the optical imaging device and an overlay image representing the distribution of radiation sources based on data from the radiation source determination section.
Patent CA-3029515-A1 (CA)
Inventor: DAVIS WALTER
IPC: F24F11/65
Filed: 2019-01-10
Abstract: Un système de chauffage, ventilation et climatisation (CVC) est configuré pour recevoir un signal dun thermostat. Le signal indique au système CVC de faire fonctionner un composant dans un mode de charge partielle. Le système CVC est également configuré pour déterminer que le composant a dépassé son enveloppe opérationnelle. En réponse à la détermination que le composant a dépassé son enveloppe opérationnelle, le système CVC est configuré pour faire fonctionner le composant selon une configuration dannulation. La configuration dannulation annule le signal afin de faire fonctionner le composant dans le mode de charge partielle.
Patent CA-3030031-A1 (CA)
Inventor: Harper-Ray Steven
IPC: H04W4/00
Filed: 2017-08-08
Abstract: The system set forth herein relates to a network of a server, proctor device and user devices that connect to provide attendance information at a gathering location. The proctor may define an area that constitutes a meeting location for a particular time. Users may connect to a network to join the meeting and when the user is within the area at a particular time, the user can authorize the transmittal of information to alter the system that the user is present. The system is able to determine the proximity of the user to identify a present status without needing to store or transmit the user's actual location to the proctor and thereby maintain a level of anonymity for the user while still confirming the user's presence at the location.
Patent CA-3031423-A1 (CA)
Inventor: SLASSI ABDELMALIK
IPC: C07C235/20
Filed: 2016-10-31
Abstract: The present application relates to novel fluorinated amide derivatives of Formula (I), to processes for preparing them, pharmaceutical compositions containing them, and their use thereof in the treatment or prevention of acute and/or chronic neurological disorders such as psychosis, epilepsy, schizophrenia, Alzheimer' disease, cognitive disorders and memory deficits, as well as chronic and acute pain and other related CNS disorders.
Patent CA-3031445-A1 (CA)
Inventor: ANDERSON CHARLES ERIC
IPC: A61B18/18
Filed: 2017-07-18
Abstract: The present disclosure provides, inter alia, a system and methods for targeted hyperthermia effective to differentially heat target organs. In certain embodiments, the system and/or method utilizes one or more pairs of inductive applicators coupled to the one or more RF generators and configured to deposit radio frequency radiation on a region of interest based on a set of configurable parameters.
Patent CA-3031612-A1 (CA)
Inventor: ROGERS TRENT
IPC: H01J9/00
Filed: 2017-04-20
Abstract: A system and method for producing a conformal electroluminescent coating on an object wherein an electrically conductive base backplane film layer is applied upon a substrate. One or more intermediate layers, such as dielectric, or phosphor film layers, is/are applied upon the conductive backplane film layer. An electrode film layer is applied upon the one or more intermediate layers using a substantially transparent, electrically conductive material. The electroluminescent phosphor is excitable by an electrical field established across the phosphor film layer such that the device emits electroluminescent light upon application of an electrical charge between the conductive backplane film layer and the electrode film layer.