baber/WOPTO huggingface dataset:
Patent CA-2537182-A1 (CA)
Title: Compositions useful for treating gastrointestinal motility disorders
Inventor: ASHBURN THEODORE T
IPC: A61K45/06
Filed: 2004-08-27
Abstract: The present invention relates to method of treating a gastrointestinal motility disorder in a subject in need of treatment comprising coadministering to said subject a first amount of a compound having 5-HT3 receptor agonist activity or a pharmaceutically acceptable salt, hydrate or solvate thereof;  and a second amount of at least one gastric acid suppressing agent (e.g., a proton pump inhibitor, an H2 receptor antagonist or a pharmaceutically acceptable salt, hydrate or solvate thereof, or an acid pump antagonist or pharmaceutically acceptable salt, hydrate or solvate thereof) wherein the first and second amounts together comprise a therapeutically effective amount.  In particular, the method is for treating GERD, including nocturnal GERD. The invention further relates to a method of treating nocturnal GERD comprising administering to a subject in need thereof a therapeutically effective amount of a compound having 5-HT3 receptor agonist activity or a pharmaceutically acceptable salt, hydrate or solvate thereof. The invention further relates to a method of increasing esophageal motility in a subject in need thereof. The method of increasing esophageal motility can be achieved by administration of a compound having 5-HT3 receptor agonist activity or a pharmaceutically acceptable salt, hydrate or solvate thereof. The coadministration can also be used to increase esophageal motility.
Patent CA-2538763-A1 (CA)
Title: Monoclonal antibodies against hmgb1
Inventor: O'KEEFE THERESA
IPC: C07K14/47
Filed: 2004-09-10
Abstract: In various embodiments, the present invention is drawn to antibodies or antigen-binding fragments thereof that bind to a vertebrate high mobility group box (HMGB) polypeptide, methods of detecting and/or identifying an agent that binds to an HMGB polypeptide, methods of treating a condition in a subject characterized by activation of an inflammatory cytokine cascade and methods of detecting an HMGB polypeptide in a sample.
Patent CA-2538853-A1 (CA)
Title: Lamp having integral voltage controller
Inventor: WEYHRAUCH ERNEST C
IPC: H01K1/62
Filed: 2006-03-08
Abstract: A lamp includes a voltage conversion circuit that converts a line voltage to a desired RMS load voltage. The voltage conversion circuit is entirely within a lamp base and uses pulse width modulation to define the RMS load voltage. The voltage conversion circuit includes a bridge that supplies the RMS load voltage to a light emitting element, a switching transistor that pulse width modulates a current supplied to the bridge, a timer connected to a gate of the switching transistor to turn the switching transistor on and off at a rate that defines the RMS load voltage, an analog-to-digital converter that converts the RMS load voltage to a digital signal, a comparator that compares an output from the converter to a preset reference value, and a circuit that adjusts the timer in response to an output from the comparator.
Patent CA-2540144-A1 (CA)
Inventor: BUGLASS JOHN GRAHAM
IPC: H01M8/06
Filed: 2004-09-24
Abstract: L'invention concerne une unité de puissance auxiliaire (APU) permettant de générer de l'électricité en combinaison avec un moteur à combustion interne comprenant une sortie de gaz d'échappement du moteur. L'APU comprend 1) une pile à combustible à oxyde solide (SOFC, 9) comprenant une entrée (6b) pour le combustible, une entrée pour l'air et/ou les gaz d'échappement et une sortie de gaz d'échappement, et 2) un reformeur d'oxydation catalytique partielle (CPOx, 5) comprenant une sortie (6a) connectée à l'entrée (6b) destinée au combustible de la SOFC (9) et une entrée (4b) destinée aux réactifs, cette entrée étant caractérisée en ce qu'elle est connectée à la sortie de gaz d'échappement du moteur par l'intermédiaire d'un évaporateur (3) comprenant une entrée (1) pour le combustible, une entrée (2) pour les gaz d'échappement et une sortie (4a) connectée à l'entrée (4b) du reformeur CPOx. L'invention concerne également un procédé permettant de générer de l'électricité à partir d'un combustible hydrocarboné à l'aide d'une APU.
Patent CA-2544303-A1 (CA)
Title: Device and method for insertion of a cannula of an infusion device
Inventor: COTE STEVE
IPC: A61M5/158
Filed: 2004-09-15
Abstract: A device for inserting a cannula of a subcutaneous infusion device into a subcutaneous layer of skin of a patient. For example, some devices automatically retract a needle used to introduce the cannula of a subcutaneous infusion device into the subcutaneous layer of skin of a patient. The device can include a housing with an internal cavity, as well as a needle coupled to the housing. The needle can be coupled to a cannula of a subcutaneous infusion device. A member can move the needle. Upon full introduction of the needle and associated cannula of the subcutaneous infusion device into a subcutaneous layer of skin of a patient, the member is automatically actuated to move the needle into the internal cavity of the housing into the retracted state while leaving the cannula of the subcutaneous infusion device in the subcutaneous layer of skin of the patient.
Patent CA-2544997-A1 (CA)
Title: Immobilized biological material with improved functionality and method for producing the same
Inventor: LACASSE RICHARD
IPC: C12Q1/527
Filed: 2006-04-27
Abstract: The present invention provides methods and systems for performing biological reactions with biologically active entities immobilized on a solid support. Particularly, the invention provides a biologically active entity immobilized a support through a spacer linked to a first linker. The spacer gives the biologically active entity a certain level of free movement relatively to the support surface to which it is fixed, thereby allowing the biological reaction to take place.
Patent CA-2545070-A1 (CA)
Title: Elastomeric glove coating
Inventor: JANSSEN ROBERT A
IPC: C08J7/056
Filed: 2004-07-06
Abstract: An elastomeric glove that contains a hydrogel coating is provided. The present inventors have discovered that the hydrogel coating is capable of improving donning (damp and/or dry) and also imparting certain other benefits to a wearer of the glove. Specifically, the hydrogel coating includes an active agent that is retained with a crosslinked hydrogel network. When the hydrogel coating is exposed to an aqueous environment, it swells, allowing the active agent to diffuse through pores and contact the skin of a wearer.
Patent CA-2550479-A1 (CA)
Inventor: HENDERSON DAVID
IPC: B65D85/30
Filed: 2006-06-19
Abstract: Packaging and delivery systems and methods for lighting devices such as streetlights. One embodiment of the invention includes a lighting device packaging and delivery system for a partially or completely preassembled and pre-wired luminaire and pole.  The packaging and methods allow the unit to be shipped and installed with very little or no assembly required. The unit, or multi-pack of units, may be packaged with all of the required components, such as the photo control and lamp, already installed.
Patent CA-2551787-A1 (CA)
Title: Composition for the treatment of chronic venous insufficiencies comprising an extract of red vine leaves and an anti-inflammatory agent
Inventor: TAKAHASHI KOICHI
IPC: A23L33/15
Filed: 2005-02-12
Abstract: This invention relates to a new composition containing the effective concentration of an aqueous extract of red vine leaves (1) and an anti- inflammatory agent (2) for preventing or alleviating the discomfort associat ed with mild-to-moderate chronic venous insufficiency of the legs. The compositions according to this invention may also contain pharmaceutically o r cosmically acceptable additives.
Patent CA-2551955-A1 (CA)
Inventor: DOWDING PETER JOHN
IPC: C10M135/10
Filed: 2006-07-13
Abstract: A method of improving the compatibility of an overbased detergent with other additives in a lubricating oil composition. The method includes the step of adding an oil-soluble, hydrocarbyl sulphonic acid to the detergent.
Patent CA-2552024-A1 (CA)
Inventor: BUMILLER GEORGE BALDWIN
IPC: G06F15/02
Filed: 2006-07-14
Abstract: A method of facilitating the entry of information for a contact to be stored by an address book application of a handheld electronic device, wherein the information is entered into a plurality of fields. The method includes receiving first information in a first one of the fields, and determining whether the first information can be used to determine second information for entry in one of the fields. If it is determined that the first information can be used to determine the second information, the method includes entering the second information in either the first one of the fields or another one of the fields. Also, a handheld electronic device having one or more routines that are adapted to implement the method described above.
Patent CA-2552614-A1 (CA)
Inventor: SWAYNE GREGORY M
IPC: B65D51/18
Filed: 2005-01-26
Abstract: L'invention concerne un ensemble couvercle pour un contenant dont la partie supérieure forme une zone d'ouverture du contenant. Cet ensemble couvercle comprend un élément inférieur présentant des dimensions calculées pour lui permettre de venir s'adapter sur partie supérieure du contenant. Cet élément inférieur du couvercle comprend une partie prolongement formée de manière à permettre l'accouplement mécanique de l'élément inférieur du couvercle avec la partie supérieure du contenant, et à former une structure périphérique présentant une surface plus grande que la zone d'ouverture du contenant. L'ensemble couvercle comprend en outre un élément supérieur conçu pour venir s'accoupler mécaniquement avec l'élément inférieur de manière à former un espace intermédiaire pouvant recevoir un article-cadeau.
Patent CA-2553851-A1 (CA)
Inventor: TRUDE GREG
IPC: B29C35/04
Filed: 2005-05-24
Abstract: A method for making a blow molded plastic container that can withstand the rigors of pasteurization of retort processing. The method includes introducing an injection molded plastic preform into a blow mold; circulating heated oil through the sidewall mold halves at a temperature of at least about 225~F  (107~C) and circulating heated oil through the base push up at a temperature of at least about 275~F (135~C). The container is blow molded from the preform and heat set within the mold. The container has enhanced crystallinity in the base as compared to when heated water is circulated through the mold.
Patent CA-2553875-A1 (CA)
Inventor: SPRAGUE STEVEN A
IPC: B23P19/06
Filed: 2005-01-28
Abstract: An automated floor assembly machine is provided for attaching longitudinally aligned floor boards to transverse positioned cross-members of a wheeled trailer. The machine comprises a carriage for longitudinal movement relative to the floor boards, a drill mounted on the carriage so that the drill is vertically and laterally movable with respect to the carriage, a fastener driver mounted on the carriage so that the fastener driver is vertically and laterally movable with respect to the carriage, a sensor operably mounted to the carriage so that the transverse mounted cross-members are detectable by the sensor, a drive motor in communication with the carriage for moving the carriage longitudinally along the floor boards into alignment with the cross-members, and a control system having a processor in operative communication with the carriage, the drill, the fastener driver, the sensor, and the drive motor.
Patent CA-2554183-A1 (CA)
Inventor: CALLEJA MICHAEL J
IPC: A63J1/00
Filed: 2006-07-27
Abstract: A staging system includes vertical posts each with rack gears disposed along their lengths. A self-propelled truss--support collar with a motor and pinion gear can climb up and down the vertical post by engaging the rack gear. A battery inside the collar provides electrical power to the motor so AC  utility power is not needed. The collar provides an anchoring plate for attachment and support of horizontal staging trusses for assembly on the ground and self-elevation overhead. A  protective track cover tape in the vertical post hides the rack gear from view. A threading roller in the collar routes the protective track cover tape around the pinion gear so it can engage the rack gear.
Patent CA-2558235-A1 (CA)
Title: A system and method for providing a reaction surface of a predetermined area for a limited volume
Inventor: BOGREN KARIN L
IPC: B01L3/14
Filed: 2005-02-14
Abstract: A cell for chemical analysis is disclosed that increases the surface area over standard discrete cells for approximately the same sample volume. The surface area is pre-coated with a reaction agent, enzyme, or chemical to facilitate testing of the sample. The cell may be in a configuration to contain any toxic reaction agent after use.
Patent CA-2559988-A1 (CA)
Title: Procede universel pour la palettisation rapide d'objets et systeme associe
Inventor: BOLZANI DANTE
IPC: B65G47/74
Filed: 2006-01-04
Abstract: La présente invention a trait à un procédé pour la palettisation rapide d'objets (100) comprenant les étapes suivantes: la disposition d'objets (100) à palettiser organisés sur un plan de collecte (400); le chargement desdits objets (100) sur un plan de support flexible (31) apte à avancer dans la direction de transfert des objets (100) dans une position sensiblement coplanaire au plan de collecte (400) et dans le prolongement de celui-ci, de sorte que le plan de support (31) reçoive lesdits objets sans glissement; le transfert desdits objets depuis le plan de support (31) vers un plan de déplacement flexible (21) qui peut effectuer un glissement coplanaire au plan de support (31) en vue de se substituer à celui-ci (31) sous les objets (100) qui cependant restent stationnaires, le transfert s'effectuant par l'activation synchrone du glissement souple du plan de support (31) et du plan de transfert (21) disposé en contact mutuel dans le prolongement de l'un et de l'autre; la prise du plan de transfert (21) avec les objets (100) sur le haut de la palette; le glissement du plan de transfert (21) sous les objets (100), maintenus stationnaires, pour leur transfert sur la palette.
Patent CA-2560046-A1 (CA)
Title: Methods for suppressing tumor proliferation
Inventor: HASEGAWA MAMORU
IPC: A61K45/00
Filed: 2005-03-15
Abstract: It is intended to provide a method of inhibiting tumor proliferation which comprises the step of inhibiting the expression of PDGF-A or the binding of PDGF-A homodimer to PDGFR.alpha.. Activation of the PDGFR .alpha.-p70S6K  signal transfer pathway by PDGF-AA, which is an important factor in tumor angiogenesis, relates to the prognosis of a patient suffering from tumor. By inhibiting the expression of PDGF-A in a tumor or a tissue around it or by inhibiting the binding of PDGF-A homodimer to PDGFR.alpha., angiogenesis in the tumor and retention of the blood vessels can be inhibited and thus the tumor proliferation can be inhibited.
Patent CA-2560167-A1 (CA)
Inventor: FLEENOR DEBRA L
IPC: A61K31/401
Filed: 2005-04-25
Abstract: The use of HMG-CoA reductase inhibitors (e.g., statins) to treat glaucoma, control intraocular pressure, preserve the trabecular meshwork, protect against ocular neurodegeneration and/or protect against glaucomatous retinopathy is described. The preferred HMG-CoA reductase inhibitors, which are statins having an RI value of 0.2 to 0.7 (e.g., pravastatin), are administered via topical application to the affected eye(s) of the patient.
Patent CA-2560264-A1 (CA)
Inventor: OEDA KENJI
IPC: C12N1/19
Filed: 2005-03-15
Abstract: A polynucleotide having the base sequence of promoter region of gene coding for trimer G protein .alpha.-subunit Gm1. In particular, there is provided the above-mentioned polynucleotide wherein the base sequence of promoter region is, for example, as follows: (1) base sequence of SEQ ID NO: 1, or (2) base sequence defined by base number 603 to 3871 of the base sequence of SEQ ID NO:  1. Further, there is provided use of the polynucleotide.
Patent CA-2561590-A1 (CA)
Title: Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues
Inventor: PEDERSEN HENRIK
IPC: C07B37/00
Filed: 2005-03-23
Abstract: The present invention relates to novel methods for the preparation of intermediates which are useful in the synthesis of cacipotriol. The present invention relates further to the use of intermediates produced with said methods for making calcipotriol or calcipotriol monohydrate.
Patent CA-2564807-A1 (CA)
Title: Methods and materials for improving plant drought tolerance
Inventor: PENNELL ROGER I
IPC: C07K14/415
Filed: 2005-04-22
Abstract: Isolated NCED3 nucleic acids and polypeptides are described herein, together with methods for using such nucleic acids and polypeptides for making transgenic plants with improved drought tolerance.
Patent CA-2566813-A1 (CA)
Inventor: FERRARI MARKUS
IPC: A61M1/10
Filed: 2005-05-10
Abstract: The invention relates to a device for epicardial support and/or resumption of cardiac activity. Said device comprises a double membrane (1) consisting of an elastic internal membrane (2), a non-expandable outer membrane (3), and a closed cavity (4) which is formed thereinbetween and can be inflated and deflated by means of a fluid. The aim of the invention is to improve one such device in such a way that a medicament can be introduced into the pericardium in a more simple manner and essentially without risk. To this end, a second cavity (7) comprising a fluid-permeable wall defining the second cavity on the side of the heart is provided on the inner side (6) of the internal membrane (2) facing the heart (5), and said second cavity (7) can be filled with a fluid by means of a separate fluid supply (9) from outside the body of the patient or a fluid contained in said cavity can be carried away towards the outside.
Patent CA-2568837-A1 (CA)
Title: Drive spindle for the main drive of a rolling stand
Inventor: BERGER MAIK
IPC: B21B35/14
Filed: 2006-04-10
Abstract: The invention concerns a drive spindle (1) for the main drive of a rolling stand, which has: a first shaft (3) for transmitting torque from a drive motor (2) to a coupling element, especially to a multiple spline profile, and a second shaft (5) for transmitting the torque from the coupling element, especially the multiple spline profile, via a swivel joint (4) to a roll (6) of the rolling stand, wherein the swivel joint (4) has a wobbler (7), which is rotationally rigidly connected with the roll (6), and a second spindle head (8), which is rotationally rigidly connected with the second shaft (5), and wherein the rotational connection between the wobbler (7) and the spindle head (8) is produced by sliding bearings and a journal (9), which is rotationally rigidly connected with the spindle head (8) but is supported in a way that allows an angle of inclination (α) between the axis of rotation (10) of the roll (6) and the axis of rotation (11) of the second shaft (5). In order to achieve improved transmission of axial forces by the swivel joint, the invention provides that a bearing element (12, 13) for absorbing forces in the direction of the axes of the second shaft (5) and the roll (6) is arranged between the wobbler (7) and the spindle head (8), such that a push rod (14) for transmitting axial forces between the wobbler (7) and the spindle head (8) is arranged between the two bearing elements (12, 13).
Patent CA-2571708-A1 (CA)
Title: Ignition bypass system
Inventor: BROWN CHARLES BARROY JR
IPC: B60R25/00
Filed: 2006-12-19
Abstract: A system and method for bypassing the ignition switch and controlling operation of an engine and an accessory drive of a vehicle, the system comprising an ignition switch, a user-activated secondary switch, a control logic circuit, and a third switch. The ignition switch controls operation of the engine that enables the engine to operate when the ignition switch is in an ON state. The user-activated secondary switch makes a connection in a parallel electrical power supply circuit to the engine and vehicle accessory drive, when the secondary switch is in the CLOSED state. The control logic circuit is responsive to the ignition switch, the secondary switch, and a user-activated vehicle control device. The third switch is associated with a user-activated vehicle control device wherein the third switch causes the logic circuit to interrupt the parallel electrical power supply circuit, when the user-activated vehicle control device is activated.
Patent CA-2574958-A1 (CA)
Inventor: BLAIR JULIAN A
IPC: A61P11/00
Filed: 2005-07-26
Abstract: Microparticles comprising iloprost are disclosed. In some embodiments, the microparticles are used to treat pulmonary hypertension. Devices comprising the microparticles are also disclosed. Combination therapies utilizing the microparticles are also provided.
Patent CA-2575354-A1 (CA)
Title: System for a three dimensional movement
Inventor: RODNUNSKY JIM
IPC: B66C13/08
Filed: 2004-07-28
Abstract: Embodiments of the invention are ideally suited for use filming movies, sporting events, or any other activity that requires fluid movement camera or other object to any position within a defined volume of space. To accomplish such positioning embodiments of the invention are configured to move an object throughout three-dimensional space by relocating one or more lines that are feed through a plurality of opposing sides of the object, these line(s) (e.g., a cable, rope, string, cord, wire, or any other flexible connective element) which support the object from above or below the object within a volume of space are arranged in way that allows the object to be rapidly moved to and from any location within the defined volume of space. For instance, the system may be arranged to perform dimensional movement using one line configured as an endless loop, one line configured as a half loop, two lines configured as endless loops or two lines configured as half loops. Other embodiments which split the two lines at the X and Y junctions may yield three and four rope embodiments which are in keeping with the spirit of the invention.
Patent CA-2575676-A1 (CA)
Inventor: FEINGOLD VLADIMIR
IPC: A61F2/16
Filed: 2005-04-28
Abstract: An intraocular and intracorneal lens (10) includes an optical portion and a corrugated haptic portion (30). Corrugations of the haptic portion may be linear or arcuate, and such corrugations may be present on both anterior and posterior surfaces of the haptic portion. The intraocular lens may be deformed before or during insertion in an eye of a patient, and may be positioned in the posterior chamber of the eye such that the optical portion is spaced anteriorly from the crystalline lens of the eye. In alternative embodiments, an intraocular or intracorneal lens of the invention may be inserted in the anterior chamber, or within the cornea, of an eye of a patient. An alternative intraocular lens includes an optical portion having a peripheral optic zone and an inner non-optic zone. Methods for correcting visual deficiencies of a patient, by insertion of an intraocular or intracorneal lens of the invention in an eye of the patient, are also disclosed.
Patent CA-2577297-A1 (CA)
Title: Occupant restraint system
Inventor: RUSCHULTE JOERG
IPC: B60R21/231
Filed: 2005-12-16
Abstract: The invention relates to an occupant restraint system for land, water, space or aircraft, in particular motor vehicles, said system comprising at least two airbags, which can be inflated in the event of a vehicle collision. The system is characterised by devices (2, 11), which are suitable for interconnecting the airbags at least temporarily in the event of a collision.