baber/WOPTO huggingface dataset:
Patent ES-8601851-A1 (ES)
Title: Preparation of cyano- or aminoalkyl substituted aromatic amines.
IPC: C07D213/64
Filed: 1984-04-06
Abstract: The present invention provides a process for preparing compounds of formula (5): NH2-AX-CH2NH2 (5) which are useful as intermediates in the preparation of compounds which are histamine H1 -antagonists. In formula (5) A is a 5-membered heterocyclic aromatic group containing up to three hetero-atoms of which no more than one can be oxygen or sulphur and from one to three can be nitrogen a 6-membered monocyclic aromatic group optionally containing up to three nitrogen hetero-atoms or a 9- or 10-membered bicyclic aromatic group optionally containing up to four hetero-atoms, of which no more than one can be oxygen or sulphur and from one to four can be nitrogen, the group A being optionally substituted with one or more groups which are inert under the reaction conditions X is a C1-5 alkylene group or a C2-5 alkenyle group which comprises (a) reacting a compound of formula (6): NO2-AX-CN (6) where A and X are as defined with reference to formula (5) with hydrazine in the presence of a transition metal catalyst to form a compound of formula (7): NH2-AX-CN (7) where A and X are as defined with reference to formula (5) and thereafter (b) reacting the compound of formula (7) so obtained with more hydrazine and Raney nickel.
Patent ES-8507511-A1 (ES)
Title: 2(1H)-Quinazolinone-1-propionic acids and analogues
IPC: A61K31/495
Filed: 1984-05-29
Abstract: Cpds. of formula (I) and their quat. salts with alkyl halides, alkali (ne earth) metal salts and the amine salt, aminoalcohol salts and aminoacid salts are new. In (I) R1 is H, NH2 or N02 R2 is H, alkyl, cycloalkyl, cycloalkylalkyl, haloalkyl or bicycloalkyl R3 and R4 are H, lower alkyl, or aryl (opt. substd. by alkyl, lower alkoxy or OH) R5 is H, lower alkyl, or opt. substd. benzyl, provided that when R5 is other than H, the cpd. is a quat. salt X is benzyl, COOH, alkoxycarbonyl, CN, CONH2, methane sulphonyl, formyl, alkanoyl, aroyl, heteroaroyl or heteroaryl and Y and Z are H or OH, at least one being OH and when both are OH, they are in the 5,6- or 6,7- posn. Intermediates of formula (II) are also new. (R6 is lower alkyl and R7 is H or is absent). Cpds. (I) are renal vasodilators and cardiovascular agents, and some intermediates in their prepn. are cardiotonic agents. Dose is 15-300 mg/kg.
Patent ES-8601858-A1 (ES)
Title: Homologues from aprotinine whose lys 15 amino acid is substituted by other amino acids, process for their preparation and their use as medicaments.
IPC: C07K14/00
Filed: 1984-07-27
Abstract: The invention relates to homologs of aprotinin with, in place of lysine, other amino acid moieties in position 15, methods for their preparation and their use as proteinase inhibitors.
Patent ES-8603755-A1 (ES)
Title: Pharmaceutical agent for ulcers of the gastro-intestinal tract.
IPC: A61K36/18
Filed: 1984-10-11
Abstract: Preventative and curative agent for gastrointestinal tract ulcers comprises as main constituent an active antiulcer component obtd. by extrn. of cassia buds with hot water and/or an alcohol.
Patent ES-8507106-A1 (ES)
Title: Salt of S-adenosyl-L-methionine, composition contaning such salt, preferably for pharmaceutical use, and process for preparing them.
IPC: A61K47/48
Filed: 1984-10-25
Abstract: The object of the invention is a salt of S-adenosyl-L-methionine, and compositions containing it, preferably for human pharmaceutical and veterinary use, such salt being characterized in that it is a salt of an organic resin consisting of a polymer or copolymer with free or salified acidic functional groups.
Patent ES-8602009-A1 (ES)
Title: Industrial prodn. of thieno:diazepine
IPC: C07D495/04
Filed: 1985-01-09
Abstract: The process comprises reaction of 2-amino-3-benzoyl-4,5-tetramethylene thiophene with N-phthalimido-acetic acid in the presence of 1-1-carbonyl diimidazol and in various media to give 2-(N-phthalimido acetylamino)-3-benzoyl -4,5-tetramethylene thiophene. The resulting cpd. undergoes hydrazinolising, with spontaneous cyclising and isolation by concn. and filtration. This gives Bentazepam of formula (I).
Patent ES-8700110-A1 (ES)
Title: High reliability double-chambered shielding system for welding.
IPC: B23K9/16
Filed: 1985-03-13
Abstract: An apparatus (50) for shielding a circumferentiai region about elongate workpieces from air contamination during welding or heat treatment includes a pair of generally cylindrical shields (52, 54) which define central openings for receiving the workpieces, and which are positioned in longtudinally spaced apart relationship about the region to be welded or heat treated. Each shield (54) includes a first annular chamber (70) and associated annular diffuser positioned adjacent the process zone, and a second annular chamber (86) and associated cylindrical diffuser (90) extending away from the zone which chambers (70, 86) are connected to independent sources of inert gas, which is directed into and out of the process zone to prevent air contamination of the process zone.
Patent ES-8604991-A1 (ES)
Title: Pharmaceutical peptides, preparation, use and intermediates.
IPC: C07K5/10
Filed: 1985-07-15
Abstract: Novel peptides of formula (I) < IMAGE > (I) wherein R1 is hydrogen, alkyl of 1 or 2 carbon atoms or an amidino group, R2 is alkyl of 1 or 2 carbon atoms, R3 is hydrogen or carbamyl, X2 is a D-radical having the structure: < IMAGE > Z1 and Z2 are the same or different and each is hydrogen, halo, nitro or trifluoromethyl and at least one is other than hydrogen, m is 2, 3 or 4 and n is 0, 1 or 2, provided that when R3 is carbamyl then n is always 1 and salts thereof. The compounds have a selectively peripheral analgesic effect when administered to mammals and also exhibit antidiarrhoeal and antitussive activity and may thus be used in human or veterinary medicine for the relief or prevention of pain, for the treatment of diarrhoea or dysentery and for the suppression of cough.
Patent ES-8607562-A1 (ES)
Title: Herpes virus specific immunological materials and methods.
IPC: A61K39/42
Filed: 1985-08-22
Abstract: Disclosed are antibody substances displaying unique, multi-specific immunoreactivities with respect to glycoprotein D of Herpes Simplex Virus types 1 and 2 (HSV gD-1 and gD-2) and structurally related compounds. Illustratively, an IgG Type 2 monoclonal antibody material produced by mouse-mouse hybridoma cell line A.T.C.C. No. HB8606 is capable of in vitro neutralization of HSV-1 and HSV-2 infectivity and of specific immunological reactivity and reversible immunobinding with natrually-occuring and recombinant gD-1 and gD-2 in both native and denatured conformations as well as with proteinaceous materials (produced, e.g., by proteolytic digestion of naturally-occurring materials, by recombinant methods, or by polymerization of amino acids) which comprise a primary structural conformation substantially duplicating part or all of that which is predicted to be extant at residues 266 through 287 of gD-1 and gD-2 [i.e., PELA(or V)PEDPEDSALLEDPV(or A)GTVA(or S)]. Disclosed also are novel procedures for detection, quantification and isolation by affinity purification of gD-1, gD-2 and structurally related compounds.
Patent ES-8700651-A1 (ES)
Title: Arphamenine derivatives, a process for their preparation and their use as medicament.
IPC: C07D239/42
Filed: 1985-09-02
Abstract: The present invention relates to an arphamenine-related compound represented by the general formula: < CHEM > wherein R1 denotes a hydrogen atom or an amino-protecting group, R2 denotes a dimethylpyrimidinyl group, R3 denotes a hydrogen atom or a hydroxyl group, and R4 denotes a hydrogen atom or a carboxyl-protecting group, and a pharmaceutically acceptable salt thereof and a process for their preparation. The compounds have immunopotentiating activity and can, therefore, be used as medicaments.
Patent ES-8609867-A1 (ES)
Title: Thermophotovoltaic technology.
IPC: F21H1/02
Filed: 1985-10-31
Abstract: A high output, narrow band thermally energized radiation source comprises a rare earth oxide radiator member that has a cross-sectional dimension in the range of five to thirty micrometers, the rare earth oxide radiator member, when heated to about 1700 DEG C., having a concentrated radiated flux over the 400-2500 nanometer wavelength range such that at least 50% of the radiated flux is within a spectral band that is less than 400 nanometers wide.
Patent ES-8706226-A1 (ES)
Title: Underground mining method for mineral deposits.
IPC: E21C41/16
Filed: 1985-11-27
Abstract: Mineral extraction in underground mines, particularly adapted to the mining of potash, whereby simultaneously with extraction and refining of the ore the waste tailings are returned to the excavated area (5) in the mine, and the space opposite to where the ore is being removed is backfilled by the tailings in order to support the mine roof. The ore is transported from the area being mined by a first set of conveyors (8, 9, 10, 11, 12) and the tailings are returned by a second set of conveyors (14, 16, 17, 18, 19), the whole conveyor system being automated and interlocked so that the failure of one conveyor unit causes shut-down of the system.
Patent ES-8800301-A1 (ES)
Title: Compositions containing antimicrobial agents in combination with stabilizers.
IPC: C08K5/59
Filed: 1986-01-02
Abstract: Composition of an antimicrobial agent and an antioxidant having improved antimicrobial activity compared to the antimicrobial agent alone. The preferred environment of the invention is a composition of a thermoplastic resin, an antioxidant, and an antimicrobial agent, the latter two being compatible with the resin. The resin composition can contain other usual additives, and can be melt processed at an elevated temperature to form articles such as films or fibers having improved antimicrobial activity. A method for improving the efficacy of an antimicrobial agent by combining it with an antioxidant is disclosed. A method for melt-processing a resin composition containing an antimicrobial material is also disclosed, wherein the resin composition includes an antioxidant. The inventors have thus discovered and solved the problem of oxidation of an antimicrobial composition, particularly a resin composition containing an antimicrobial agent, which arises when the composition is processed at elevated temperatures, as are typically encountered when forming a fiber or film of the composition.
Patent ES-8704930-A1 (ES)
Title: 1-Substituted 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoline-carboxylic-acid derivatives, their preparation and their use as medicaments.
IPC: C07D401/04
Filed: 1985-12-12
Abstract: The present invention relates to new 1-substituted derivatives of 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, their preparation and their application as drugs. The 1-substituted derivatives of 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid according to the invention correspond to the general formula I: < IMAGE > (I) in which: R represents a methyl radical, a 2-hydroxyethyl radical, a vinyl radical, a cyclopropylmethyl radical, a propyl radical, a cyclopropyl radical, a 2-fluoroethyl radical, a methylamino radical or an ethylamino radical, as well as their physiologically acceptable alkali metal or alkaline earth metal salts. They are useful as antimicrobial agents, in particular as antibacterial and fungistatic agents.
Patent ES-8701746-A1 (ES)
Title: Condensed furanones, process for their preparation and their pharmaceutical use.
IPC: C07D409/04
Filed: 1986-01-30
Abstract: 1-Oxo-1,3,4,7-tetrahydrobenzofuranes of the formula < IMAGE > in which X is O or S, R is optionally substituted phenyl or heteroaryl, R1 is OH, monoalkylamino or dialkylamino, and R2 is an acyl or esterified carboxy radical, or pharmacologically acceptable salts thereof, which are active in circulation, e.g. they increase myocardial contractility, increase the flow of Ca2+ into the cell, increase blood pressure, reduce blood sugar, reduce swelling of mucous membranes and affect the salt and/or fluid balance.
Patent ES-8702881-A1 (ES)
Title: Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2-receptor antagonist activity
IPC: A61K31/426
Filed: 1986-01-31
Abstract: Histamine H2-receptor antagonists of the formula < IMAGE > I wherein A, m, Z, n and R1 are as defined herein, and their nontoxic pharmaceutically acceptable salts are novel anti-ulcer agents which are prepared by ring closure of a substituted ethanediimidamide of the formula < IMAGE > II
Patent ES-8701001-A1 (ES)
Title: Rack drive
IPC: F16H19/04
Filed: 1986-02-26
Abstract: A rack-type drive for displacing a movable part longitudinally and horizontally relative to a stationary part has a longitudinally extending rack fixed on one of the parts which is formed above the rack with a longitudinal slot through which the rack is exposed upward and the other part is above the one part. A drive shaft rotatable about a horizontal and transverse upper axis on the other part is provided with a drive gear operatively engaged down through the slot with the rack. A pair of outer idler rollers generally below and longitudinally flanking the drive gear are rotatable about respective horizontal and transverse lower axes and a pair of inner idler rollers rotatable about the transverse axis on the drive shaft coaxially flank the drive gear and have outer peripheries lying relative to the axis radially outside the gear. A belt extending along and covering the slot to both longitudinal sides of the other part passes under the outer idler rollers and over the inner idler rollers in engagement with the peripheries thereof but out of contact with the drive gear.
Patent ES-8705267-A1 (ES)
Title: Method of manufacturing a composite element of a tripod homokinetic joint.
IPC: F16D3/205
Filed: 1986-06-11
Abstract: 1. A method of producing a composite element for a homokinetic tripod joint consisting of a sleeve (11) having sliding ramps (r) for the rollers (13) of a tripod and which is assembled on an end member (16) adapted to be rendered rigid with a connecting means (17) for receiving an input shaft and of which the open end carries a cap (18) for retaining a bellows seal (20), according to which the sleeve (11) is shaped from a portion of tubular bar the inner configuration of which resembles three lobes (l) for receiving rollers (13), the faces (f) and the inner sliding ramps (r) of the said rollers (13) being subjected to a broaching process prior to the heat treatment and correction of the faces (f), followed by an electron beam operation to weld the end member (16) and to connect the cap (18) by welding, according to which the operation of broaching the faces (f) of the sleeve (11) which defines the reference faces in relation to the vertical positioning of the sleeve is followed by an internal vertical broaching of the ramps (r) and according to which a heat treatment is carried out which follows measurement of the spacing between the ramps (r) of one and the same lobe (l) upon modification of the axial geometry of the sleeve due to a ball centred therein actually passing through the sleeve, a stage which is followed by measurement of the new spacing which determines the amplitude of the displacement of a standard tripod in contact with the various ramps in order to ensure that the sleeve is restored to shape prior to rectification of the faces (f).
Patent ES-8801247-A1 (ES)
Title: 3-Imidazolylmethyl-1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives
IPC: C07D521/00
Filed: 1986-06-16
Abstract: Compounds of formula (I). < IMAGE > [wherein R<1> is hydrogen C1-10 alkyl, C3-7 cycloalkyl, C3-6 alkenyl, phenyl or phenyl-C1-3alkyl, and one of the groups represented by R<2>, R<3> and R<4> is hydrogen, C1-6 alkyl, C3-7 cycloalkyl, C2-6 alkenyl or phenyl-C1-3alkyl and each of the other two groups, which may be the same or different, is hydrogen or C1-6alkyl and physiologically acceptable salts and solvates, e.g. hydrates, thereof] are potent selective antagonists at "neuronal" 5-hydroxytryptamine receptors and are useful in the treatment of migraine and psychotic disorders such as schizophrenia.
Patent ES-8802494-A1 (ES)
Title: Heterocyclic amide derivatives.
IPC: C07D209/18
Filed: 1987-07-31
Abstract: The invention concerns novel, pharmaceutically useful, amide derivatives of certain benzoheterocyclylalkanoic acids (and related tetrazoles and acylsulphonamides) of the formula I and salts thereof, wherein the radicals R1, R2, L, X, Y, Z, A1, Q, A2 and M have the meanings set out in the specification. The invention also includes pharmaceutical compositions incorporating a formula I compound or a salt thereof, a process for the manufacture of the said compound, together with intermediates for use in the latter process. < IMAGE > I
Patent IE-911144-A1 (IE)
Title: Substituted 3-thia- and 3-oxa-alkyl flavones, process for their preparation, their application and drugs based on these compounds as well as intermediates
Inventor: BECK GERHARD
IPC: A61P9/10
Filed: 1991-04-05
Abstract: Substituted 3-thia- and 3-oxa-alkylflavones of formula I I wherein R, R1, R2, R3, R4+L, X, m and n have the indicated meanings, a process for the preparation of these compounds and their use as medicaments and pharmaceutical preparations are described. In addition, new intermediates for the preparation of the compounds of formula I are described.
Patent IE-903463-A1 (IE)
Title: Wall panel with thermoacoustic insulation characteristics
IPC: E04B2/24
Filed: 1990-09-26
Abstract: This invention relates to a panel for constructing walls having thermo-acoustic insulation properties, with which support walls provided with properties of considerable strength and good thermo-acoustic insulation are rapidly obtained at a relatively low cost.
Patent IE-903662-A1 (IE)
Title: Method and apparatus for processing photosensitive material
IPC: G03C7/44
Filed: 1990-10-12
Abstract: This invention relates to a method and apparatus for processing photosensitive material and, in particular, to a compact table top apparatus for developing silver halide photosensitive materials, such as a sheet or web of photographic film or paper or plate, and its use.
Patent IE-921232-A1 (IE)
Title: Immunoassay for detecting group b streptococcus
Inventor: JENNINGS HAROLD J
IPC: C07K19/00
Filed: 1992-04-16
Abstract: Immunoadsorbent combinations for the detection and diagnosis of group B streptococcus polysaccharide antigen, comprising an insoluble carrier, a capture agent having an affinity for specifically binding to the trirhamnose epitope of group B streptococcus antigen and having the formula alpha -L-Rhap(1->2)- alpha -L-Rhap(1->2) alpha -Rhap-1- wherein Rhap is rhamnose, and an antigen marker agent having an affinity for binding to monorhamnose epitope of group B streptococcus polysaccharide antigen of formula alpha -L-Rhap-1- when the group B streptococcus polysaccharide is bound to the carrier. An immunoassay method test kit and polyclonal antibody are also described.
Patent IE-921881-A1 (IE)
Title: New packaging/containerization system
Inventor: GOUGE SAMUEL T
IPC: B65D85/84
Filed: 1992-07-01
Abstract: A containerisation system which comprises a concentrated hazardous and solid composition in a cold water soluble or water dispersible bag wherein the bag has a residual inflatability. The hazardous composition comprises especially an agrochemical.
[EP0518629A1]
Patent LU-504005-A1 (LU)
Title: System and method for synchronous recovery of carbon dioxide and nitrogen gas from flue gas by chemical method and psa method
Inventor: ZHANG YONGCHUN
IPC: B01D53/96
Filed: 2022-11-02
Abstract: A system and method for synchronous recovery of carbon dioxide and nitrogen gas from flue gas by chemical method and PSA method. This system for synchronous recovery of carbon dioxide and nitrogen gas from flue gas by chemical method and PSA method comprises a carbon dioxide chemical method recovery system, a carbon dioxide refining liquefaction system a nitrogen gas PSA concentration and purification system; the carbon dioxide chemical method recovery system comprises a carbon dioxide absorption column, a carbon dioxide regeneration column, a heat exchanger and a first congealer. This system for synchronous recovery of carbon dioxide and nitrogen gas from flue gas by chemical method and PSA method has a good recovery effect of carbon dioxide and nitrogen gas, and can effectively save energy.
Patent AT-505440-A1 (AT)
Title: Hydraulic system i.e. dispenser-slave-force deflection system, for e.g. deep drawing press, has piston, where counter pressure on piston is generated with compressible container i.e. hydraulic cylinder, that is located within piston
IPC: F15B15/14
Filed: 2007-05-30
Abstract: The hydraulic system has a slidable piston (9) supported in an accumulator (6) in a liquid-proof manner. The piston is pressurized by a hydraulic fluid, where a corresponding counter pressure is exerted on the piston. The counter pressure on the piston is generated with a compressible container i.e. hydraulic cylinder, on a side that is turned away from the hydraulic fluid. The container encloses a predetermined gas amount, where the container is located within the piston.
Patent WO-9608098-A1 (WO)
Title: Verfahren zur datenübertragung zwischen informationsverarbeitenden stationen bzw. geräten
Inventor: BOCK NORBERT
IPC: H04L69/40
Filed: 1995-08-17
Abstract: Bei einem Verfahren zur Datenübertragung nach dem Token-passing-Verfahren zwischen an ein doppelt ausgeführtes (redundantes) Netzwerk (5, 6) angeschlossenen informationsverarbeitenden Stationen (1, 2, 3, 4) für die Automatisierungstechnik arbeiten alle Stationen nach einem konstanten synchronisierten Zeitzyklus (9). Dieser ist in drei Phasen geteilt, die in der Reihenfolge Synchronisierphase (13, 14), Broadcastphase (10) und Messagephase (11) ablaufen. Von jeder Station (1, 2, 3, 4) wird zyklisch jeder der beiden Busse (5, 6) für sich und unabhängig voneinander auf Funktionsfähigkeit bzw. Fehler (Störung) überwacht, wobei jedem Fehler im gesamten Netzwerk ein eindeutiges Fehlergewicht als geradzahliger Wert zugeordnet ist. Jede Station (1, 2, 3, 4) teilt die entweder selbst beobachteten Zustände oder von einer anderen Station (1, 2, 3, 4) gemeldeten Zustände mit dem höchsten Fehlergewicht auf den für die sendende Station gerade aktiven Bus (5, 6) den anderen Stationen (1, 2, 3, 4) im Netzwerk in der Broadcastphase (10) mit . Jede Station (1, 2, 3, 4) entscheidet sofort aus Basis jenes selbst beobachteten oder von einer anderen Station (1, 2, 3, 4) gemeldeten Fehlers mit dem höchsten Fehlergewicht, welcher der beiden Busse (5, 6) zum aktiven und welcher zum passiven wird. Im Ein-Fehler-Fall erfolgt somit eine automatische Umschaltung auf jenen Bus (5, 6), d.h. dieser wird zum aktiven, der in Ordnung ist. Nach der Behebung des Fehlers, z.B. einer Leitungsunterbrechung auf einem der beiden Busse (5, 6), wird automatisch wieder in den Redundanzbetrieb umgeschaltet.
Patent WO-0229387-A1 (WO)
Title: Sonde fluorescente et dispositif destine a etre fixe sur celle-ci
Inventor: FRANCIS ROBERT JOHN
IPC: G02B6/24
Filed: 2001-10-02
Abstract: L"invention concerne un dispositif destiné à être fixé à une sonde fluorescente ou phosphorescente, générant un arrêt de faisceau et définissant un volume de mesure reproductible indépendant du volume d"un fluide dans lequel la sonde est insérée. Le dispositif (32) utilise un élément (36) pourvu d"une surface noire brillante (42) pour absorber tout excès de lumière d"excitation émise de l"extrémité (14) d"une sonde à fibres optiques et qui n"est pas absorbée par un fluide intermédiaire. L"élément (36) est également incliné par rapport à l"extrémité (14) de la probe de façon que sa surface (42) réfléchisse toute lumière d"excitation non absorbée (44) (affaiblie en raison de l"absorption par l"élément) afin de l"empêcher de pénétrer l"extrémité (14) de la sonde. Ceci empêche sensiblement la lumière d"excitation d"entrée de se mélanger avec la lumière d"émission reçue à l"extrémité (14).