baber/WOPTO huggingface dataset:
Patent EA-016659-B1 (EA)
Title: Ethylenediamine derivatives for the treatment of mycobacterial infections
Inventor: PROTOPOPOVA MARINA NIKOLAEVNA
IPC: A61K31/445
Filed: 2003-05-19
Abstract: The present invention relates to substituted ethylenediamine derivatives effective for the treatment of diseases caused by microorganisms, in particular tuberculosis. Besides, the invention relates to compositions comprising the substituted ethylenediamine derivatives for the treatment of infectious diseases. The use of said compositions for the treatment of mycobacterial infections and for manufacturing medicament for the treatment of the mycobacterial infections are
Patent EA-010405-B1 (EA)
Title: Secreted protein family
Inventor: MICHALOVICH DAVID
IPC: A61K38/00
Filed: 2004-04-30
Abstract: This invention relates to a new family of secreted proteins, termed the SECFAM3 family, its family members including the novel human proteins INSP123, INSP124 and INSP125, herein identified as secreted proteins containing a von Willebrand Factor type C (vWFC) domain, and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of diseases.
Patent EA-010056-B1 (EA)
Title: Nucleic acid constructs
Inventor: FULLER JAMES
IPC: C07K14/035
Filed: 2004-10-11
Abstract: A nucleic acid construct comprising a chimeric promoter sequence and a cloning site for insertion of a coding sequence in operable linkage with the chimeric promoter, wherein the chimeric promoter sequence comprises: (a) a hCMV immediate early promoter sequence; (b) exon 1 and at least a part of exon 2 of the hCMV major immediate early gene; and (c) a heterologous'intron provided in place of the intron A region of the hCMV major immediate early gene.
Patent EA-011315-B1 (EA)
Title: Estimating noise at one frequency by sampling noise at other frequencies
Inventor: WILLEN DENNIS E
IPC: G06F17/50
Filed: 2006-01-17
Abstract: A method, apparatus and computer program for improving the signal-to- noise ratio of a signal S(t), S(t) containing Signal and noise, are disclosed. A measurement of S(t) at a frequency-of-interest is obtained. Noise measurements of S(t) at one or more noise frequencies where the Signal portion of S(t) is expected to be small are obtained. The noise at the frequency-of-interest is estimated using the noise measurements at the one or more noise frequencies. The estimated noise is subtracted from the measurement of S(t) at the frequency-of-interest.
Patent EA-013482-B1 (EA)
Title: Ir-absorbing intaglio ink
Inventor: DEMARTIN MAEDER MARLYSE
IPC: B41M3/14
Filed: 2006-11-16
Abstract: Pasty ink for the engraved steel die printing process, having a viscosity value above 3 Pa.s, preferably above 5 Pa.s and comprising an infrared absorbing material, wherein said infrared absorbing material is a transition element compound whose IR-absorption is a consequence of electronic transitions within the d-shell of transition element atoms or ions.
Patent EA-018259-B1 (EA)
Title: Substituted quinazolines
Inventor: FRANKLIN RICHARD
IPC: A61K31/505
Filed: 2007-11-19
Abstract: This invention relates to the discovery of 3- and 5-substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
Patent EA-015386-B1 (EA)
Title: Method to enhance clarification in a mixing reactor and said mixing reactor
Inventor: LILJA LAUNO
IPC: B01J8/24
Filed: 2008-02-28
Abstract: The invention relates to a mixing reactor for mixing a liquid and pulverous solid, clarification the solution that is formed and discharging the clarified solution from the mixing reactor, in the lower section of which a fluidized bed is formed. The invention also relates to a method for mixing a liquid and pulverous solid into each other in a fluidized bed, for clarification the solution that is formed and for discharging the clarified solution from the mixing reactor.
Patent EA-018589-B1 (EA)
Title: Use of a composition comprising formoterol and beclometasone dipropionate for the prevention and/or treatment of an exacerbation of asthma
Inventor: CHIESI PAOLO
IPC: A61K31/167
Filed: 2008-04-16
Abstract: The present invention relates to the use of a composition comprising a fixed combination of a) formoterol, a pharmaceutically acceptable salt or solvate thereof or a solvate of such a salt; and b) beclometasone dipropionate; for the manufacture of a medicament for use in the prevention and/or treatment of an exacerbation of asthma, intermittent asthma and/or episodes in chronic asthma during the maintenance therapy of asthma with the same composition for symptomatic relief, when needed.
Patent EA-018724-B1 (EA)
Title: Indole compounds
Inventor: TALLEY JOHN JEFFREY
IPC: C07D401/12
Filed: 2007-08-07
Abstract: The invention relates to indole derivatives of Formula Aor pharmaceutically acceptable salts thereof, wherein V, W, X, Y, Z, J, K, L are C; M is N; Qis N; Q, Q, Qand Qare C; a) P, P, P, P, Pand Pare C, or b) one of P, P, P, P, Pand Pis N, and the rest are C; A and A' taken together are =O; which can be used for treating pain, inflammation and other states.
Patent EA-017754-B1 (EA)
Title: Convex crested insert with deflected wedge surfaces
Inventor: FAN XIAOBING
IPC: E21B10/16
Filed: 2010-05-26
Abstract: The invention relates to carbide inserts used on roller cone bits for oil and gas drilling applications as well as for other geological drilling applications, and more specifically, relates to the convex crested insert with deflected wedge surfaces. The insert comprises a cylindrical portion and a composed of a conical crest base, a top surface and two opposing wedge surfaces. Upper ends of the two wedge surfaces are merged smoothly with top surface of the insert. The specific feature of the structure is that top surface of the crest portion is convexed outwardly and forms a smooth curve surface which is higher in the middle and lowers down gradually to each end. Said two wedge surfaces are slant wedge surfaces, so that a width of the top surface and therefore a width of the insert crest are tapered from one end to the other. Advantages of this invention include: help for rock breaking and therefore, it can increase drilling efficiency of the cutters and lower the overall drilling cost; higher anti-breakage capability and longer working life; and, when inserts of this invention are used as heel row cutting elements on bit, contact area between wider end of the top surface of the insert and borehole wall is larger and therefore the gouging action applied on the borehole wall is higher and can also achieve better gage protection of the bit.
Patent EA-023267-B1 (EA)
Title: Method for treating and/or preventing migraine
Inventor: IKEDA JUNICHI
IPC: A61P25/06
Filed: 2009-07-23
Abstract: The present invention relates to a method for treating and/or preventing migraine, which comprises administering an effective amount of a compound having a selective adenosine Areceptor antagonistic activity, represented by the following formula (II):wherein radicals are defined in the claims, as a single active ingredient. Said compound having a selective adenosine Areceptor antagonistic activity has an affinity for an adenosine Areceptor higher by 10 times or more than that for an adenosine Areceptor. The present invention also relates to the use of the compound having a selective adenosine Areceptor antagonistic activity, represented by the following formula (II) for the manufacture of a therapeutic and/or preventive agent for migraine.
Patent EA-025440-B1 (EA)
Title: Compositions for the prophylaxis and treatment of dermatological/mucosal diseases, and uses thereof
Inventor: FELEKI ATTILA
IPC: A61P17/00
Filed: 2009-07-28
Abstract: The present invention provides a composition for the prophylaxis and treatment of dermatological and mucosal diseases/disorders, containing clinoptilolite; physiologically acceptable magnesium salt; water; non-cationic carrier, where the mean particle size of said clinoptilolite is from 100 nm to 20 μm and the total molar amount of magnesium ions is higher than the total molar amount of calcium ions. The present invention further relates to the use of said composition for the prophylaxis and treatment of skin diseases, skin conditions, or mucosal diseases, wherein the skin diseases or skin conditions are selected from inflammatory skin diseases, increased fibroblast proliferation, pruritus, xerosis, bruises, hyperproliferation states of the skin, or transepidermal water loss, wherein the mucosal diseases are selected from aphthas, oral ulcers, stomatitis, injuries of mucosal membranes, gingivitis, or diseases of the nasopharyngeal mucosa.
Patent EA-023110-B1 (EA)
Title: Guardrail
Inventor: LEONHARDT PATRICK A
IPC: E01F15/00
Filed: 2010-03-15
Abstract: A breakaway support post for a guardrail includes an upper post member and a lower post member. The upper and lower post members are overlapping and configured such that the upper and lower post members are non-rotatable relative to each other about an axis extending in an axial impact direction. In one embodiment, a tensile fastener extends in the axial impact direction and connects overlapping portions of the upper and lower post members. In another embodiment, a shear fastener extends transversely to the axial impact direction and is the only connection between the upper and lower post members. In another aspect, a guardrail assembly includes first and second rail sections, with a deforming member deforming the first rail section as it moves relative to the second rail section. Methods of using and assembling a guardrail assembly are also provided.
Patent EA-021517-B1 (EA)
Title: Biologically active additive and process for producing same
Inventor: NAROVLYANSKIJ ALEXANDR NAUMOVICH
IPC: A23L1/30
Filed: 2010-11-11
Abstract: The invention relates to dietary and prophylactic biologically active food additives (BAAs), in particular those consisting of plant raw materials, and to processes for producing same and can be used as a food additive for people and domestic animals for reducing blood cholesterol levels, stimulating protein glycosylation and preventing infectious and cardiovascular diseases. The technical result of the use of the proposed BAA consists in providing a means for reducing blood cholesterol levels, stimulating protein glycosylation and preventing infectious and cardiovascular diseases. The biologically active additive comprises at least one polyprenyl phosphate or polyprenyl pyrophosphate with from 7 to 30 isoprene bonds or a mixture of different polyprenyl phosphates and polyprenyl pyrophosphates which have been adsorbed on a solid sorbent, in particular sorbitol, lactose, starch; and, in addition, beta-sitosterol. The biologically active additive is produced by means of dissolving a mixture of polyprenyl phosphates and/or polyprenyl pyrophosphates in an organic solvent, adding a sorbent to the resultant solution and subsequently mixing and removing the solvent by distillation. Beta-sitosterol can be added along with the sorbent.
Patent EA-025052-B1 (EA)
Title: Multifilament yarn construction
Inventor: NELIS MISCHA
IPC: D04C1/12
Filed: 2011-04-29
Abstract: The invention concerns a multifilament yarn construction comprising a core part and a sheath part, the core part comprising a plurality of core filaments, and the sheath part comprising a plurality of sheath filaments. Furthermore, the invention concerns members comprising the multifilament yarn construction and uses of the multifilament yarn construction and the members according to the invention.
Patent EA-023161-B1 (EA)
Title: Triazolopyrazine compounds as nk3 receptor selective antagonists, pharmaceutical composition and methods for use in nk3 receptors mediated disorders
Inventor: HOVEYDA HAMID
IPC: C07D487/04
Filed: 2011-04-04
Abstract: The present invention is directed to novel compounds of formula Iand their use as therapeutic compounds.
Patent EA-028876-B1 (EA)
Title: System and method for low damage fracturing
Inventor: HARTMAN RYAN
IPC: E21B43/267
Filed: 2008-07-22
Abstract: A system includes a wellbore in fluid communication with a formation of interest, a fracturing slurry including a carrier fluid with a low amount of a viscosifier, a first amount of particulates including a first average particle size between about 100 and 2000 μm, a second amount of particulates including a second average particle size between about three and ten times smaller than the first average particle size, and a third amount of particulates including a third average particle size smaller than the second average particle size. A sum of all of the particulates in the fracturing slurry exceeds about 16 pounds per gallon of the carrier fluid (1920 kg/m). The system further includes a pumping device that creates a propped fracture in the formation of interest with the fracturing slurry, and a removal agent that removes the second amount of particulates from the fracture and/or the third amount of particulates from the propped fracture.
Patent EA-026774-B1 (EA)
Title: Method for gyroscopic stabilization of a lidar in the horizon plane and a device for implementation thereof
Inventor: DUBINSKIJ ANDREJ IGOREVICH
IPC: G01C21/18
Filed: 2014-07-22
Abstract: The object of the invention is a method for gyroscopic stabilization of a lidar in the horizont plane and a device for implementation of the method. The invention is related to the field of vibration protection engineering and is designed for vibration insulation and gyroscopic stabilization in respect of the horizon plane of mobile lidars and associated navigation systems, laser range-finders and other similar equipment mounted on ground transport vehicles or water transport media. The method according to the invention includes installation of a lidar on the top surface of a gyro-stabilized platform linked to a support structure, vibration insulation of the gyro-stabilized platform by provision of resilient gimballess coupling with the support structure and spatial stabilization of the lidar relative to the line of the horizon by transferring the gyro-stabilized platform to a suspended state in the atmosphere in respect of the surface of the moving object by means of providing reduced pressure in a vacuum cavity with an elastic side surface disposed between the top and bottom surfaces of the gyro-stabilized platform. The condition of the platform with the lidar passing into a suspended state is determined from the relationship according to the invention. The device for implementing the method comprises a gyro-stabilized platform having a bottom surface 1 and a top surface 2 carrying a lidar 3, the surfaces being rigidly linked to each other by rods 4, a vacuum cavity 5 having its upper end connected to a support surface 7 and its lower, movable end connected to the bottom surface 1. The support surface 7 is rifidly fixed on support posts 8 mounted on the bearing surface 9 of the moving object. An inertial gyroscopic stabilizer 10 is connected to the bottom surface 1. The invention provides higher reliability and precision of direction of the lidar line of sight in space during sounding of objects, complete vibration insulation and independent stabilization of the lidar relative to the line of horizon while the device as a whole is significantly simpler.
Patent EA-032749-B1 (EA)
Title: Petroleum recovery process
Inventor: MILAM STANLEY NEMEC
IPC: C09K8/58
Filed: 2013-06-25
Abstract: A process is provided for recovering petroleum from a formation. An oil recovery formulation comprising dimethyl sulfide that is first contact miscible with a liquid petroleum composition is introduced into a petroleum bearing formation and petroleum is produced from the formation.
Patent EA-027729-B1 (EA)
Title: Electrolytic cell for metal electrowinning
Inventor: FIORUCCI ALESSANDRO
IPC: C25C7/02
Filed: 2014-04-03
Abstract: The invention relates to a cell for metal electrowinning equipped with a device useful for preventing the adverse effects of dendrite growth on the cathodic deposit. The cell comprises a porous conductive screen, positioned between the anode and the cathode, capable of stopping the growth of dendrites and avoiding that they reach the anode surface.
Patent EA-031082-B1 (EA)
Title: Process for the conversion of a paraffinic feedstock
Inventor: JANSSEN ANDRIES HENDRIK
IPC: C10G65/02
Filed: 2014-10-30
Abstract: The invention relates to a process for the conversion of a paraffinic feedstock that comprises at least 50 wt.% of compounds boiling above 370°C and which has a paraffin content of at least 60 wt.%, an aromatics content of below 1 wt.%, a naphthenic content below 2 wt.%, a nitrogen content of below 0.1 wt.%, and a sulphur content of below 0.1 wt.%, the process comprising: a) subjecting the paraffinic feedstock to a hydroprocessing step to obtain an at least partially isomerised feedstock; b) separating the at least partially isomerised feedstock into one or more middle distillate fractions and a first residual fraction, wherein step a) is carried out by contacting the paraffinic feedstock with a first catalyst having hydrocracking and hydroisomerising activity and then with a second catalyst having hydrocracking and hydroisomerising activity, wherein the second catalyst is more active in hydroisomerisation and less active in hydrocracking than the first catalyst.
Patent EA-035199-B1 (EA)
Title: Improved il-6 antibodies
Inventor: SCHMIDT MICHAEL MARCH
IPC: A61P27/02
Filed: 2015-11-06
Abstract: Improved IL-6 antibodies are provided. Uses of the antibodies in the treatment of IL-6 related diseases, e.g., ocular diseases such as diabetic macular edema, are disclosed.
Patent EA-036112-B1 (EA)
Title: 7-PHENYLETHYLAMINO-4H-PYRIMIDO[4,5-d][1,3]OXAZIN-2-ONE COMPOUNDS AS MUTANT IDH1 AND IDH2 INHIBITORS
Inventor: BAUER RENATO ALEJANDRO
IPC: C07D498/04
Filed: 2017-12-08
Abstract: Provided is a compound, as defined herein, or a pharmaceutical composition containing the compound, for use in treating cancer including mutant IDH1 or IDH2, having the structure
Patent ES-2176066-B1 (ES)
Title: Identificacion de adulteraciones vegetales por reaccion en cadena de la polimerasa (pcr) de acidos nucleicos.
Inventor: MARTIN MARQUINEZ MERCEDES
IPC: C12Q1/686
Filed: 2000-02-02
Granted: 2003-12-16
Abstract: Identificación de adulteraciones vegetales por reacción en cadena de la polimerasa (PCR) de ácidos nucleicos. Aprovechando que cada especie vegetal tiene secuencias específicas de bases en sus ácidos nucleicos y el hecho de que las diferencias de secuencias se pueden poner de manifiesto identificando, por diferentes técnicas, los fragmentos de ácidos nucleicos amplificados por la reacción en cadena de la polimerasa (PCR), demostramos la viabilidad de un método para la identificación en productos comerciales de adulteraciones con material de origen vegetal. En aplicaciones convencionales del método analítico, partiendo de unos pocos mg de muestra comercial, podemos ya identificar adulteraciones de pimentón comercial con tan solo un 1% de polvo de tomate. Se reivindica la aplicabilidad general del método y su uso para identificar adulteraciones con tomate y adulteraciones en pimentón.
Patent ES-2158829-B1 (ES)
Title: Metodo para la copia de discos, cintas y soportes de informacion similares y correspondiente maquina automatica publica para la copia o duplicacion de soportes de informacion.
Inventor: TARODO ORTI JOSE VICENTE
IPC: G11B5/86
Filed: 2000-02-28
Granted: 2002-03-16
Abstract: Método para la copia de discos, cintas y soportes de información similares, y correspondiente maquina automática pública para la copia o duplicación de soportes de información. Comprende las etapas de introducción de moneda/s, ficha/s o tarjeta (10), la recepción (11) de un soporte de lectura y (12) de escritura, la duplicación (13), la expulsión de los dispositivos (14) y la desconexión (15). La máquina comprende un mueble de sustentación (1), un dispositivo de lectura (2), uno de escritura (4), un dispositivo receptor de monedas (6), y eventualmente un mecanismo de control y pantallas de visualización. De aplicación industrial en la duplicación de dispositivos de almacenamiento de información y en la fabricación de los aparatos correspondientes.
Patent ES-2186478-B1 (ES)
Title: Arco flexible con anillas en los extremos para abertura de orificios nasales.
Inventor: LUNA PARDO MANUEL
IPC: A61F5/08
Filed: 2000-06-19
Granted: 2004-09-16
Abstract: Arco flexible con anillas en los extremos para abertura de orificios nasales. Consiste en un cordón o arco flexible caracterizado porque une dos aros o anillas una en cada extremo del cordón, se coloca una anilla en cada orificio nasal ajustándose a las paredes nasales, permitiendo el paso del aire exterior a través del interior de cada anilla y evitando gracias a éstas la obstrucción del orificio respiratorio.
Patent ES-2277468-B1 (ES)
Title: Peptidos bioactivos y derivados, procedimiento de produccion, cepas de enterococcus faecalis productoras de dichos peptidos bioactivos y sus aplicaciones.
Inventor: MUGUERZA MARQUINEZ BEGONA
IPC: A61K35/744
Filed: 2003-05-21
Granted: 2008-07-01
Abstract: Péptidos bioactivos y derivados, procedimiento de producción, cepas de enterococcus faecalis productoras de dichos péptidos bioactivos y sus aplicaciones. Se describen unos péptidos bioactivos, en particular, péptidos con actividad inhibidora de la enzima convertidora de la angiotensina y/o con actividad antihipertensiva in vivo, los cuales pueden obtenerse por fermentación de un sustrato que comprende una o más proteínas, péptidos o fragmentos de los mismos que contienen la secuencia de aminoácidos de dichos péptidos bioactivos con la bacteria Enterococcus faecalis. Dicha bacteria y dichos péptidos bioactivos pueden ser utilizados en la industria farmacéutica y alimentaria, en la elaboración de composiciones farmacéuticas, productos alimentarios, productos alimentarios funcionales y suplementos alimentarios.
Patent ES-2273528-B1 (ES)
Title: Tapadera para turbina de freno de ascensores.
Inventor: PORRAS VILA F JAVIER
IPC: B66B5/00
Filed: 2003-07-25
Granted: 2008-04-01
Abstract: La Tapadera para turbina de freno de ascensores es un complemento de mi Patente titulada Patín aéreo de freno, mejorado. En ella, se establecía un sistema de frenado de caídas, aplicado a los saltos desde un avión. Se trata de un sistema que se puede acoplar, prácticamente, sin modificación alguna, a los techos de los ascensores. Pero, para que el ascensor pueda descender en su funcionamiento normal y el patín de freno no se lo impida, necesita estar tapado. De ahí que se presente aquí la tapadera para turbina de freno de ascensores, que es una tapadera horizontal con la base curvada con un eje dentado en su centro, y un mango que termina en el techo del ascensor, dentro de la cabina. La tapadera, al ascender el mango, obturará la cara hueca de la carcasa del patín aéreo de freno, por donde éste recibe el aire en su descenso. Con sólo estirar del mango, se liberará la tapadera y el patín de freno se activará.