baber/WOPTO huggingface dataset:
Patent MY-184362-A (MY)
Title: Inhalable nicotine formulations, and methods of making and using thereof
Inventor: ZAMEL NOE
IPC: A61K9/00
Filed: 2016-09-15
Abstract: The present invention provides dry powder formulations comprising nicotine, methods of using the same, and methods for making the same. The dry powder formulations may further comprise excipients, therapeutic agents, and flavor components. The dry powder formulations may be manufactured by dry processes and wet processes.
Patent MY-190647-A (MY)
Title: Compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof
Inventor: HU OLIVER YOA-PU
IPC: C07D319/06
Filed: 2016-09-26
Abstract: The present invention relates to compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof. (No suitable figure)
Patent MY-174244-A (MY)
Title: Coated metal plate
Inventor: SHUICHI SUGITA
Filed: 2016-09-21
Abstract: The purpose of the present invention is to provide a coated metal plate that has excellent stain resistance , that does not cause interference patterns to occur, and that has excellent design properties. This coated metal plate comprises a metal plate having an average surface roughness Ra(metal plate) of 0.40 ?m or less and a coating film that is fonned on at least one surface of the metal plate, that substantially comprises a composition represented by the compositional formula K2O?xSiO2 (3.5 :S x :S 6.8) , and tha t has an average thickness t of 0.2-3.0 ?m. The average thickness t of the coating film and the average surface roughness Ra(coating film) of the coating film satisfy formula ( I). Formula (1): Ra(coating film) 2: 0.03 / t + 0.15.
Patent MY-193316-A (MY)
Title: Damage-resistant gloves with breach-indicator function
Inventor: MIRTSCHIN NIKOLAUS
IPC: B29K105/00
Filed: 2018-01-23
Abstract: The present invention relates to a multi-layered latex cover, particularly a glove, comprising a main body and a rim. The main body comprises an outer latex layer, an inner latex layer and an intermediate layer comprising particles. The rim essentially consists of the agglutinated outer and inner latex layer. The particles in the intermediate layer are chemically functionalized with a compound comprising hydrophobic groups. Prior to functionalization, the particles are characterized by a mean diameter of ? 100 ?m and a surface comprising exposed OH groups. The invention further relates to a method of producing the multi-layered cover, comprising the steps of providing a former and sequentially immersing it in a first coagulator solution, a first latex dispersion, a particle suspension and a second latex dispersion. (Fig. 1)
Patent MY-195253-A (MY)
Title: Methods for Celiac Disease Using Lactobacillus Strains
Inventor: AGARDH DANIEL
IPC: A61K35/74
Filed: 2018-01-12
Abstract: The present invention relates to at least one probiotic strain of Lactobacillus for use in a subject for the prevention and/or treatment of celiac disease autoimmunity (CDA), or for use in the prevention and/or treatment of celiac disease (CD). A preferred composition for use according to the invention is a composition comprising a combination of Lactobacillus paracasei and Lactobacillus plantarum, especially L. paracasei 8700:2 (DSM 13434) in combination with L. plantarum HEAL 9 (DSM 15312).
Patent MY-195818-A (MY)
Title: Layer Structures for Photovoltaic Devices and Photovoltaic Devices Including The Same
Inventor: CHEN LE
IPC: H01L31/0224
Filed: 2018-11-15
Abstract: A layer structure (10) for a photovoltaic device (100) comprising: a transparent conductive oxide layer comprising indium tin oxide (20); a layer of tin dioxide (30) adjacent to the indium tin oxide of the transparent conductive oxide layer; and a layer of zinc magnesium oxide (40) adjacent to the layer of tin dioxide, wherein the layer of zinc magnesium oxide is an alloy of zinc oxide and magnesium oxide. A photovoltaic device (100) comprising: a transparent conductive oxide layer comprising indium tin oxide; a layer of tin dioxide disposed on the indium tin oxide of the transparent conductive oxide layer; a layer of zinc magnesium oxide adjacent to the layer of tin dioxide, wherein the layer of zinc magnesium oxide is an alloy of zinc oxide and magnesium oxide; and an absorber layer disposed on the layer of zinc magnesium oxide, wherein the absorber layer comprises cadmium, tellurium, selenium, or any combination thereof. (Fig. 1)
Patent SG-10201902203V-A (SG)
Title: Eutectic formulations of cyclobenzaprine hydrochloride
Inventor: LEDERMAN SETH
Filed: 2015-09-18
Abstract: EUTECTIC FORMULATIONS OF CYCLOBENZAPRINE HYDROCHLORIDE The present invention relates to pharmaceutical compositions and methods of manufacturing the same, comprising a eutectic of Cyclobenzaprine HCl and mannitol. Figure: 6
Patent SG-11201810215R-A (SG)
Title: Mold release sheet for semiconductor compression molding and semiconductor package which is molded using same
Inventor: SUZUKI MASAHIKO
IPC: B32B27/14
Filed: 2016-05-20
Abstract: MOLD RELEASE SHEET FOR SEMICONDUCTOR COMPRESSION MOLDING AND SEMICONDUCTOR PACKAGE WHICH IS MOLDED USING SAME A release sheet for semiconductor compression molding includes a release layer that includes particles, and a base layer. The content ratio of the particles in the release layer is from 5% by volume to 65% by volume.
Patent SG-11201903525R-A (SG)
Title: Method for removing heavy metals from an aqueous solution
Inventor: PASHLEY RICHARD MARK
IPC: C02F1/24
Filed: 2017-10-20
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization 111111111111111111111010111111111111111111111111111111111111111111111111111111110111111 International Bureau (10) International Publication Number (43) International Publication Date .....0\"\"\" WO 2018/071985 Al 26 April 2018 (26.04.2018) WIP0 I PCT (51) International Patent Classification: BO3D 1/012 (2006.01) CO2F 1/62 (2006.01) TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). CO2F 1/24 (2006.01) (21) International Application Number: Published: PCT/AU2017/051145 — with international search report (Art. 21(3)) (22) International Filing Date: 20 October 2017 (20.10.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 2016904251 20 October 2016 (20.10.2016) AU (71) Applicant: NEWSOUTH INNOVATIONS PTY LIMITED [AU/AU]; Rupert Myers Building, Level 2, Gate 14, Barker Street, Sydney, New South Wales 2052 (AU). (72) Inventors: PASHLEY, Richard Mark; 22 Mackellar _ Crescent, Cook, Australian Capital Territory 2614 (AU). RAHMAN, Abul Fazal Mohammed Mokhlesur; 30 — William Wilkins Crescent, Isaacs, Australian Capital Ter- = ritory 2607 (AU). MAKAVIPOUR, Fatemeh; 48/100 Chewings Street, Page, Australian Capital Territory 2614 =_ (AU). TASEIDIFAR, Mojtaba; 168 Hoskins Street, Franklin, Australian Capital Territory 2913 (AU). (74) Agent: GRIFFITH HACK; GPO Box 4164, North Syd- ney, New South Wales 2001 (AU). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, _ AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, = = = HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, — KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, = MG, MK, MN, MW, MX, MY MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, = = TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. = (84) Designated States (unless otherwise indicated, for every = — kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, = — 1-1 in EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, GC 01 1-1 N (54) Title: METHOD FOR REMOVING HEAVY METALS FROM AN AQUEOUS SOLUTION --.... (57) : The invention provides a method for removing a dissolved heavy metal from 1-1 0 COON an aqueous solution. The method comprises dissolving in the aqueous solution a foaming 0 R ) - N SH agent of formula (I) or a salt thereof. The method further comprises passing a gas through the ei i ii (1) aqueous solution to form a foam and separating the foam from the aqueous solution. C
Patent SG-11201906263P-A (SG)
Title: Method and device for random access
Inventor: LIU JIANHUA
IPC: H04W72/04
Filed: 2017-01-05
Abstract: METHOD AND DEVICE FOR RANDOM ACCESS Provided are a method and device for random access, which can implement flexible random access. The method comprises: a first device determining a first basic parameter set used by a first message transmitted in a random access process; and the first device, using the first basic parameter set, sending the first message to a second de-vice, or the first device receiving the first message sent by the second device. (FIG. 3)
Patent SG-11201907891X-A (SG)
Title: Combination therapy for the treatment or prevention of tumours
Inventor: REDDELL PAUL WARREN
IPC: A61P35/00
Filed: 2018-03-23
Abstract: WO 18/ 17 055 9 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 27 September 2018 (27.09.2018) WIPO I PCT ill 1111u°11101VIIIVIIIVIIIolo VIII Em ono imio oimIE (10) International Publication Number WO 2018/170559 Al Untreated lesion 15 1,tg Compound 1 • (51) International Patent Classification: A61K 31/336 (2006.01) A61P 35/00 (2006.01) (21) International Application Number: PCT/AU2018/050277 (22) International Filing Date: 23 March 2018 (23.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 2017901027 23 March 2017 (23.03.2017) AU (71) Applicant: QBIOTICS LIMITED [AU/AU]; 7 Penda Street, Yungaburra, Queensland 4884 (AU). (72) Inventors: REDDELL, Paul Warren; 7 Penda Street, Yungaburra, Queensland 4884 (AU). CULLEN, Jason Kingsley; Unit 16, 175-205 Thornside Road, Thornside, Queensland 4159 (AU). BOYLE, Glen Mathew; 65 Hills- don Road, Taringa, Queensland 4068 (AU). PARSONS, Peter Gordon; 317 Swann Road, St Lucia, Queensland 4067 (AU). GORDON, Victoria Anne; 7 Penda Street, Yungaburra, Queensland 4884 (AU). (74) Agent: GRIFFITH HACK; GPO Box 1285, Melbourne, Victoria 3001 (AU). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) (54) Title: COMBINATION THERAPY FOR THE TREATMENT OR PREVENTION OF TUMOURS (57) : The present invention relates to a combination therapy for tu- mours comprising the administration of an epoxytigliane compound and an im- Fig 7A mune checkpoint inhibitor. In particular embodiments, there is a method of treat- B16-F10-OVA ing a tumour and/or treating or preventing one or more bystander tumours with the therapy. Pharmaceutical compositions and kits containing epoxytigliane compounds and immune checkpoint inhibitors are also described. a-PD-1 or a-CTLA-4 (200 py) i.p. 5 5 5 (...) measure treated and I I I I untreated lesions day -2 0 2 4 6
Patent IS-2453-B (IS)
Inventor: NISHIBE YOSHIHISA
IPC: A61K9/10
Filed: 1999-12-20
Abstract: Aqueous medicinal composition for application to the mucosa comprises a water insoluble or poorly water soluble substance and at least one pharmaceutical and has an osmotic pressure of less than 290 mOsm.
Patent ZA-9683-B (ZA)
Title: Melting method for an electric arc furnace with alternative sources of energy and relative electric arc furnace
Inventor: GENSINI GIANNI
IPC: F27B3/20
Filed: 1996-01-05
Abstract: Melting method for an electric arc furnace with alternative sources of energy for the melting of iron-based alloys, the electric furnace (10) including tuyéres (13) positioned on the bottom to deliver oxygen, at least one tuyére (15) to deliver coal dust which works in the area of contact between the bath of molten metal (16) and the layer of slag (22), at least one supersonic lance (12) cooperating with a lance (29) to deliver coal dust, these lances (12, 29) having a working position (12c, 29c) in which the supersonic lance (12) is positioned in close proximity to the surface of the molten metal (16) and the lance (29) to deliver coal dust is positioned in the vicinity of the surface of the layer of slag (22), and a plurality of burners (28) positioned on the cooled sidewalls (31) of the furnace (10) and delivering oxygen-based gases and combustible substances, whereby at least two first burners (28) work with the action of one burner supporting the action of the next one, the furnace (10) being charged with one or more charges which provide for a first step of start-up of the melting and a second step of melting, a refining step and a tapping step being included, in which method in the first step of start-up of the melting at least one second burner (28e) collaborates in freeing quickly the path of introduction of the supersonic lance (12) and of the lance (29) to deliver coal dust, at least one third burner (28a) is directed towards the centre of the furnace (10) in cooperation with the area of the emerging of the oxygen delivered by an oxygen tuyére (13) to the surface of the bath, the burners (28) work in the first step as burners and in the second step as subsonic oxygen lances and in the third step are substantially shut off, the oxygen tuyéres (13) deliver oxygen in a great quantity and at a low pressure, the delivery of the carbonaceous substances is directed towards the centre of the furnace (10) and takes action in cooperation with the slag (22) both above the slag and between the slag and the molten metal, the reactions Fe + O = FeO, FeO + C = Fe + CO are caused to take place within the bath of molten metal (16) just above the surface of the molten metal (16) and at about the thickness of the slag (22), which is processed to be foamy slag, and the reaction CO + O = CO2 is caused to take place just above the surface of the molten metal (16) and at about the thickness of the slag (22).  Electric arc furnace which carries out the above method. <IMAGE>
Patent AT-403364-B (AT)
Inventor: SCHOENEGGER-FOESLEITNER ERICH
IPC: B62D33/06
Filed: 1996-02-27
Granted: 1998-01-26
Abstract: The vehicle has a cab bourn on springs. It has a three point symmetrical bearing with two bearings at the front and one (1) at the rear in the cab's centre. This is attached to an off-centre position of the vehicle's frame (3) via a strut (2). The strut be comprised of a holder (4) with upper and lower guide rockers (5,6). It may have a gallows shaped bracket (7) angled up and away from the frame, and a spring damper (8).
Patent AT-404533-B (AT)
IPC: A01F15/07
Filed: 1997-03-17
Granted: 1998-12-28
Abstract: The winding machine for wrapping block-shaped balls of goods with foil consists of a roller device (2) to rotate the balls about a horizontal axis and a winding device (3) to apply the foil with a foil outlet (4) rotating relative to the roller device about a vertical axis. The roller device has two hinged supports pivoting about two parallel axes with delivery devices located at the same height incorporating the balls of goods between them. The hinged supports are coupled together in the sense of opposing pivoting movements by a device (12).
Patent CH-640692-B (CH)
Inventor: RACINE MARTIAL
IPC: G04F1/00
Filed: 1982-02-08
Abstract: The electronic device, fulfilling for example the function of a parking disc, comprises a quartz clock. A circuit (IC I) makes it possible automatically to define the starting time as a function of the time of arrival in this instance of a signal for setting the device into operation. The circuit includes registers in which is stored at least one correspondence table making it possible to define the starting time as a function of the time of arrival, taking account on the one hand of the regulations in force and on the other hand of the selected parking mode (blue zone, red zone, etc). <IMAGE>
Patent HU-194058-B (HU)
Inventor: HODSAGI FERENC
IPC: A63B61/04
Filed: 1984-01-26
Abstract: A találmány tárgya hordozható hálófeszítő bérén-   (2) kiképzett megvezetésbe (21) csatlakozik. Atartó- dezés labdajátékokhoz, amelynek hálófeszítő rúdjai   elemeknek (1) támasztó rúdjai (4,5) vannak, amelyek (3), azok rögzítésére szolgáló egy-egy tartóeleme (1)   részére a tartóelem (1) palástján további nyflások (11) van. A tartóelemek (1) töltőnyílással (6) ellátott lég-   vannak kiképezve és a·támasztó rudak (4, 5) a nyílá- alább egy, zárt üreget (8) tartalmaznak, és a töltőnyí-   sokon (11) át a merevítő kötőelemen (2) lévő megve- lás (6) eltávolítható záiókupakkal (7) rendelkezik. A   zetésekbe (22) illeszthető módon vannak kialakítva, tartóelemeken (1) belül merevítő kötőelem (2) van el-   A támasztó rudak (4, 5) talajjal érintkező végei pedig helyezve, a hálófeszítő rúd (3) a tartóelem (1) tetején   tapadó korongokkal (9) vannak ellátva. levő nyíláson (10) keresztül a merevítő kötőelemen  -1-
Patent LT-3189-B (LT)
Title: Device for connection of beams of separable frame structures
Inventor: RUETER EWALD
IPC: E04B1/58
Filed: 1993-03-09
Abstract: In a device for releasably connecting the girders of framework structures, claws (3) are mounted at the free end of each girder, the claws engaging in recesses (9) of joint plates (4, 5) connectible by means of a screw (6). The joint plates (4, 5) are formed as circular discs one of which has a central through opening for a screw and another of which has a central threaded bore for the screw (6), the discs having the recesses (9) in their faces directed towards one another, concentric with the central opening or bore. The claws (3) of the girder are formed by projections in the form of circular sectors having a claw (3) at each side, curved to correspond to the configuration of the grooves, the claws being insertable between the joint plates, (4, 5), and being engageable in the recesses (9) of the plates. <IMAGE>
Patent LT-3033-B (LT)
Title: Device adapted for storing and identificating of polygraphic produce
Inventor: SLAPSYS VILIUS
IPC: A47B65/00
Filed: 1993-05-20
Abstract: Device for the identification and storage of books and other printed articles applies to office equipment and may be used in libraries, reading-room premises, book depositories and archives. The invention aims to expand the functional limits of the device in regard of information index substitutability and protection. For this purpose a supporting shelf of the device (5) is shaped by technological integration together with a vertical socket (2) that has a U shape profile (7), replaceable information indexes (8) and transparent protecting tailpieces (1) for insertion.
Patent YU-49476-B (YU)
Title: New herbicidal compositions
Inventor: GAMBLIN ALAN
IPC: A01N37/22
Filed: 1995-07-24
Abstract: A method of controlling the growth of weeds at a locus which comprises applying to said locus a herbicidally effective amount of:     (a) a 4-benzoylisoxazole of formula I: <CHEM>     wherein     R is hydrogen or -CO2R<3>, where R<3> is as defined below;   R<1> is cyclopropyl; R<2> is selected from halogen, -S(O)pMe and C1-6 alkyl or haloalkyl,     n is two or three; p is zero, one or two; and   R<3> is C1-6 alkyl;     (b) a chloroacetamide herbicide; and (c) a safening agent. om
Patent RS-49926-B (RS)
Inventor: CARPINO PHILLIPA
IPC: C07K/
Filed: 1996-12-26
Abstract: Jedinjenje formule:racemske-diastereomerske smeše i optički izomeri navedenih jedinjenja i farmaceutski prihvatljive soli datih jedinjenja, naznačenih time što su e 0 ili 1 n i w su svaki nezavisno 0,1 ili 2 i uslovljeni da w i n nemogu biti oba O u isto vreme; Y je kiseonik ili sumpor; R1 je vodonik, -CN, -(CH2)qN(X6)C(O)X6, -(CH2)qN(X6)C(O)(CH2)t-A1, -(CH2)qN(X6)SO2(CH2)t-A1, -(CH2)qN(X6)SO2X6, :(CH2)qN(X6)C(O)N(X6)(CH2)t-A1, -(CH2)qN(X6)C(O)N(X6)(X6), -(CH2)qC(O)N(X6)(X6), -(CH2)qC(O) N(X6)(CH2)t-Al, -(CH2)qC(O)OX6, -(CH2)qC(O)O(CH2)t-A1, -(CH2)qOX6, -(CH2)qOC(O) X6, -(CH2)qOC(O)(CH2)t-A1, -(CH2)qOC(O)N(X6)(CH2)t-A1, -(CH2)qOC(O)N(X6)(N)6, -(CH2)qC(O)X6, -(CH2)qC(O)(CH2)t-A1, -(CH2)qN(X6)C(0)OX6, -(CH2)qN(X6)S02N(X6)(X6), -(CH2)qS(O)mX6, -(CH2)qS(O)m(CH2)t-A1, -( C1-C10)alkil, -( CH2)t-A1, -( CH2)q-(C3-C7 )cikloalkil, -( CH)q- Y1( C1-C6)alkil, -(CH)q-Y1(CH2)t-A1 ili -(CH)q-Y1 -(CH2)t-(C3-C7)cikloalkil; gde su alkil ili cikloalkil grupe definisane u R1 opcijski supstituisane sa (C1-C4)alkil, hidroksil, (C1-C4)alkoksi, karboksi, -CONH2 -S(O)m(C1-C6)alkil, -C02(C1-C4)alkil estar, lH-tetrazol-5-il ili 1,2 ili 3 fluor, Y1 je O, S(O)m, -C(O)NX6, -CH=CH-, -C=C-, -N(X6)C(O)-, -C(O)NX6-, -C(O)O-, -OC(O)N(X6)- ili -OC(O)-; q je 0,1,2,3 ili 4; t je 0,1,2 ili 3; navedene (CH2)q i (CH2)t grupe mogu svaka biti opcijski supstituisane sa (C1-C6)alkoksi, karboksi, -CONH2, -S(O)m(C1-C6)alkil, -C02(C1-C4)alkil estar, 1H-tetrazol-5-il ili 1,2 ili 3 fluor, ili 1 ili 2 (C1-C4)alkil,- R2 je vodonik, (C1-C8)alkil, -(C0-C3)alkil-(C3-C8)cikloalkil, -(C1-C4)alkil-A1 ili Al; gde su alkil grupe i cikloalkil grupe u definiciji R2 su opcijski supstituisane sa hidroksi,C(O)OX6, -C(O)N(X6)(X6), -N(X6)(X6), -S(O)m(C1-C6)alkil, -C(O)A1, -C(O)(X6), CF3, CN ili 1,2 ili 3 halogen;- R3 je Al, (C1C10)alkil, -(C1-C6)alkil-A1, -(C1-C6)alkil-(C3-C7)cikloalkil, -(C1-C5)alkil-X1(C1-C5)alkil, -(C1-C5)alkil-X1(C0-C5)alkil-Al, ili -(C1-C5)alkil-X1-( C1-C5)alkil-( C3-C7 )cikloalkil, gde su alkil grupe u definiciji R3 opcijski supstituisane sa -S(O)m(C1-C6)alkil, -C(O)OX6, 1,2,3,4 ili 5 halogen ili 1,2 ili 3 OX3; X1 je O, S(O)m, -N(X2)C(O)-, -C(O)N(X2), -OC(O)-, -C(O)O-, -CX2=CX2-, N(X2)C(O)O-, -OC(O)N(X2)- ili -C::C-; R4 je vodonik , (C1-C6)alkil ili (C3-C7)cikloalkil, ili R4 je uzet zajedno sa R3 i ugljenikov atom preko koga su povezani i formiraju (C3-C7)cik1oalkil, (C5-C7)cikloalkenil, parcijalno zasićeni ili potpuno zasićen 4-8 članski prsten koji ima od 1 do 4 heteroatoma nezavisno odabranih iz grupe koja se satoji od kiseonika, sumpora i azota, ili neki biciklični sistem koji se sastoji od parcijalno zasićenih, potpuno nezasićenih ili potpuno zasićenih 5-6 članskih prstena koji imaju od 1 do 4 heteroatoma nezavisno odabranih iz grupe koja se satoji od kiseonika, sumpora i azota; X4 je vodonik ili (C1-C6)alkil ili X4 je uzet zajedno sa R4 i azotom za koji je X4 prikačen, i ugljenikov atom za koji