baber/WOPTO huggingface dataset:
Patent DK-3055409-T3 (DK)
Inventor: LAWRENCE SHAWN
IPC: C12N5/16
Filed: 2014-10-10
Granted: 2018-07-30
Abstract: An improved method for large scale production of proteins and/or polypeptides in cell culture is provided. In accordance with the present invention, the method provides for culturing cells that have metabolically shifted. The use of such a method or system allows high levels of protein or polypeptide production and reduces accumulation of unwanted metabolic waste such as lactate. Proteins and polypeptides expressed in accordance with the present invention may be advantageously used in the preparation of pharmaceutical, immunogenic, or other commercial biologic compositions, such as antibodies.
Patent DK-0458996-T3 (DK)
Inventor: REBHAN HORST
IPC: B65D51/24
Filed: 1990-05-29
Granted: 1995-01-09
Abstract: In a container for receiving liquids, fluids or flowable materials, with a receiving container part (1) with an opening (5) for the materials, a cap part (3) which can be placed on the opening (5), and a suspension device for the container, which has a suspension bow (17) which runs across the upper side (18) of the cap part (3) and can be brought from a position which is at least partially integrated into the contour of the cap part (3) into an extended suspension position, the suspension bow (17) is, to simplify the construction and the handling of the suspension device, equipped with a slide guide mounted in the cap part (3), via which it can be displaced from the integrated position into the suspension position.
Patent DK-0420177-T3 (DK)
Inventor: KOSTER NORBERT H L DR-ING
IPC: G08C17/00
Filed: 1990-09-26
Granted: 1995-04-10
Abstract: The invention relates to a device for accurately measuring the distribution of local, physical values at a site which is normally inaccessible (for example in living tissue) and for wireless transmission of the measurements and of an identification sign for the transponder transmitting the measurements to an evaluation unit positioned outside the measurement site. By coordinating the measurement to the site of the transponder, the distribution of the physical values to be measured can be determined. Thus, it is possible, for example, to determine the temperature distribution in a tissue fragment, the bending load at different positions of bones, or the body temperature of various laboratory animals in a cage. Since the energy supply is wireless and is effected by means of an electromagnetic field, the service life of the transponders is not limited by exhaustable energy sources. <IMAGE>
Patent DK-0419192-T3 (DK)
Inventor: KIMURA MAKIKO
IPC: B41J2/175
Filed: 1990-09-17
Granted: 1994-05-24
Abstract: The ink-jet head includes an ink container (1000) containing ink, and a recording head, to be supplied with ink, connected to the container. A porous material (900) in located in the container. A supply port (2200) is located in the container supplying ink to the recording head. An opening (5) in the container allows the inside of the container to communicate with the atmosphere. The cavities provided by non-contact between the porous material and the container inside walls exist where the communicating port is formed, opposite from the opening. The head includes a thermal energy generating unit causing film boiling.
Patent DK-0435843-T3 (DK)
Inventor: HEGDE SHRIDHAR GAJANAN
IPC: A01N43/78
Filed: 1990-12-21
Granted: 1994-07-04
Abstract: Disclosed herein are 2- or 6-fluoromethyl-3-pyridinecarboxylate derivatives with 5-[(heterocyclic)ylidene]amino substitution useful as herbicides and herbicide intermediates.
Patent DK-0453483-T3 (DK)
Inventor: TADROS MAHER EBEID
IPC: C11D7/50
Filed: 1990-01-05
Granted: 1996-03-18
Abstract: Cleaning solutions for printed circuit boards are disclosed, comprising dialkyl esters of C4 to C6 acids and from 0 to 40 percent of a non-ionic surfactant.
Patent DK-0458849-T3 (DK)
Inventor: MARKUSSEN ERIK KJAER
IPC: C12N9/98
Filed: 1990-02-16
Granted: 1995-08-28
Abstract: The enzyme containing granulate comprises a core with a primary enzyme and cellulose fibres or artificial fibres in an amount of between 1.5 and 40 % by weight, based on the weight of the core, surrounded by a shell comprising a binder, a filler, and granulating agents, and a secondary enzyme, and a sustained release coating between the core and the shell. The enzyme containing granulate contains a primary enzyme and a secondary enzyme sensitive to the primary enzyme, and the secondary enzyme is released fast in the washing solution, whereas the primary enzyme is released slowly in the washing solution. This improves washing performance. The enzyme containing granulate is produced by introduction of the components thereof into a granulating drum.
Patent DK-0446312-T3 (DK)
Inventor: ZEN GIUSEPPE
IPC: E04H17/14
Filed: 1990-08-14
Granted: 1995-05-08
Abstract: A structure, useful as a balustrade or fence, comprising a rail attached to a plurality of pickets. The rail has first and second longitudinal members that are pressed together to form the rail. There are spaced openings formed in one longitudinal member with an open edge for each opening at an edge of the longitudinal member. Channels are formed in each side of the picket member, adjacent an end of the picket member. There are projections on the first and second members, adjacent to each opening. Each projection is received in a channel of a picket. The arrangement of channels and projections provides a rattle-free structure. The structure can be further improved by the incorporation of a settable compound to assist in the pressing together of the first and second members.
Patent DK-0449041-T3 (DK)
Inventor: MUELLER HANNS-PETER DR
IPC: C08L1/06
Filed: 1991-03-14
Granted: 1997-02-17
Abstract: Blends aus Cellulose und einem Polyurethan(harnstoff) haben gegenüber anderen Cellulose-Blends verbesserte Eigenschaften und lassen sich als biologisch abbaubares Verpackungsmaterial verwenden.
Patent DK-0451924-T3 (DK)
Inventor: CAO HOAI-CHAU
IPC: C11D3/386
Filed: 1991-04-12
Granted: 1999-09-20
Abstract: A three component enzyme stabilization system including boric acid, citric acid and calcium ions helps maintain the enzyme activity of aqueous built detergent compositions in accelerated aging (multiple freeze-thaw cycles). The preferred detergent compositions are "softergents" and also include a clay softener, a mixture of anionic, nonionic and amphoteric surfactants, and detergent builder(s).
Patent DK-0462948-T3 (DK)
Inventor: GIANNESSI FABIO
IPC: A61P25/28
Filed: 1991-06-20
Granted: 1995-03-20
Abstract: Pharmaceutical compositions for enhancing the process of learning and memory are disclosed, that contain as active principle a 3-amino- epsilon -caprolactam of formula (1) <CHEM> Wherein R is selected from the group consisting of hydrogen, formyl and acetyl. Orally or parenterally administrable pharmaceutical compositions in unit dosage form comprise from about 100 to about 500 mg of a compound of formula (1).
Patent DK-0506862-T3 (DK)
Inventor: WELBOURNE TOMAS C
IPC: G01N33/74
Filed: 1990-12-21
Granted: 1995-04-18
Abstract: Described is a method for evaluating the nitrogen metabolizing growth condition of an animal. This is preferentially determined by evaluating glutamate levels in a test sample from the animal. The method has a preferred application in determining when to use a hormonal agent of nitrogen balance (HANB) and the optimum dosage of a HANB. Methods of promoting growth by administering glutamate alone or in combination with a HANB are disclosed.
Patent DK-0517820-T3 (DK)
Inventor: MEGLASSON MARTIN DURHAM
IPC: A61P3/00
Filed: 1991-02-27
Granted: 1997-06-09
Abstract: The present invention provides a method for treating or preventing certain metabolic disorders comprising the systemic administration of 3-guanidinopropionic acid.
Patent DK-0545607-T3 (DK)
Inventor: YURI GELFGAT
IPC: B22D11/115
Filed: 1992-11-24
Granted: 1998-03-16
Abstract: There is provided a device and a method for continuous casting of a homogeneous alloy consisting of immiscible metals. The device includes a crystallizer, fillable with a melt prepared from the metals, a homogenizer, a crystallizer, a feeder for passing a D.C. current through the melt in the crystallizer, in order to produce therein an electric field of predeterminable intensity. There is also provided an electromagnet adapted to produce therein a magnetic field of predeterminable induction, a nozzle adapted to direct jets of a coolant at selected regions of the crystallizer to cause the melt to solidify, and a puller to extract solidified portions of, the alloy melt from the crystallizer. The electric field and the magnetic field are applied thereto so as to cross one another, and the interaction between the electric field produced by the D.C. current passing through the melt and the magnetic field produced by the electromagnet modify the effect of gravity, producing an indifferent equilibrium of the components of the alloy. <IMAGE>
Patent DK-0571415-T3 (DK)
Inventor: DELLA VALLE FRANCESCO
IPC: A61F2/04
Filed: 1992-02-10
Granted: 1995-12-04
Abstract: PCT No. PCT/EP92/00285 Sec. 371 Date May 24, 1994 Sec. 102(e) Date May 24, 1994 PCT Filed Feb. 10, 1992 PCT Pub. No. WO92/13579 PCT Pub. Date Aug. 20, 1992The present invention is drawn to medical devices comprised of biodegradable guide channels for use in repair and regeneration of nerve tissue. The guide channels are comprised of threads embedded in a matrix and coextruded with active factors wherein both the matrix and the threads are comprised of biocompatible and bioabsorbable esters of hyaluronic acid.
Patent DK-0569496-T3 (DK)
Inventor: MATHIS GERARD
IPC: G01N21/64
Filed: 1992-01-27
Granted: 1995-03-06
Abstract: PCT No. PCT/FR92/00069 Sec. 371 Date Jul. 28, 1993 Sec. 102(e) Date Jul. 28, 1993 PCT Filed Jan. 27, 1992 PCT Pub. No. WO92/13264 PCT Pub. Date Aug. 6, 1992.The present invention relates to a method employing at least one luminescent tracer compound and a luminescent compound used as an internal reference, which, when exposed to the same excitation wavelength, are capable of emitting at difference wavelengths,  lambda 2 and  lambda 1 respectively, either by direct luminescence or by the induction of a luminescent emission, and correcting the measurement of the luminescence emitted by the tracer compound at wavelength  lambda 2 on the basis of the measurement of the luminescence emitted by the reference compound at wavelength  lambda 1.
Patent DK-0593552-T3 (DK)
Inventor: HUGHES JOHN K
IPC: A61K9/22
Filed: 1992-06-30
Granted: 1997-10-27
Abstract: Drug substances in beadlet form are prepared with high bulk density spray-coating onto inert core particles, using coater-granulator apparatus, comprising: forming a fluidised bed of particles of inert core material within the processing chamber of a coater-granulator apparatus by passing a gaseous current between the rotating disc and the inner wall of the processing chamber; and forming beadlets by layering a drug onto the particles of the core material by spray-coating with a solution of the drug; characterised in that during beadlet formation, the spray-coated particles are (i) transferred to a drying zone surrounding the processing chamber, (ii) carried through the drying zone by a gaseous current, and (iii) returned to the processing chamber; the recirculation process being continued until beadlets having the desired drug load are formed.
Patent DK-0563691-T3 (DK)
Inventor: ANDERSSON THORBJOERN
IPC: B65D5/74
Filed: 1993-03-18
Granted: 1996-07-01
Abstract: The disclosure relates to a packaging material (1) with an integrated opening arrangement (4), and a method of producing the same. The foundation layer (3) of a packaging material web (1) or a packaging material sheet is provided with a hole (5) or a hole indication (15). The hole (5) or the hole indication (15) is covered by a thin thermoplastic strip (7). Thereafter, the packaging material (1) is finished, with other laminate layers (8, 9, 10, 12). In such instance, the outer layer (12) will wholly cover the strip (7). When the strip (7) is torn off, the hole (5) is exposed in that those layers (8, 9, 10, 12) which are sealed to the strip (7) accompany the strip (7) when torn off. <IMAGE>
Patent DK-0588583-T3 (DK)
Inventor: FILLMORE WILLIAM E
IPC: B65D50/04
Filed: 1993-09-13
Granted: 1997-06-16
Abstract: A child resistant closure (20) which can be readily opened by an adult comprising an outer closure member (21) having a base wall (23), a peripheral skirt (24) and a bead (27) on the outer closure member for retaining an inner closure (22) member for limited axially outward movement relative to the outer closure member. A push tab (30) is hinged to the base wall of the outer closure member and projects through an opening in the base wall of the outer closure member. The push tab can be depressed into a plurality of spaces provided between circumferentially spaced ramp-type projections (36) or castellations on the inner closure member. One of the castellations is provided with a stop surface (38) such that when the push tab is depressed in that location, as indicated by indicia on the outer closure member and inner closure member, the closure can be unthreaded from a container to remove the closure. <IMAGE>
Patent DK-0640143-T3 (DK)
Inventor: NODA ASAO
IPC: A61K48/00
Filed: 1992-12-15
Granted: 2001-07-16
Abstract: An expression vector cDNA library derived from senescent cells has been used to isolate cDNA clones that encode inhibitors of DNA synthesis. Such inhibitors play a role in cellular senescence and aging. Antisense nucleic acids reduce the inhibition of DNA synthesis.
Patent DK-0642364-T3 (DK)
Inventor: KAUFMAN ROBERT J
IPC: A61M1/36
Filed: 1993-05-26
Granted: 1997-07-21
Abstract: Methods and apparatus for practical extracorporeal separation of fluorochemicals from clinically fluorochemical-containing whole blood of a patient. The methods incorporate centrifugal apheresis devices, preferably with low extracorporeal volumes, that provide a means for continuously removing separated fluorochemical-enriched fractions from the centrifuge during processing and return of whole blood-enriched fractions to the patient.
Patent DK-0668858-T3 (DK)
Inventor: WESTPHALEN KARL-OTTO
IPC: A01N47/36
Filed: 1993-10-30
Granted: 1997-01-27
Abstract: Sulfonylureas of the general formula I  where R1 is a methyl or ethyl group; R2 is C1-C3-alkoxycarbonyl, a C1-C2-alkyl group which carries 1 to 5 fluorine atoms, methylsulfonyl, dimethylaminosulfonyl, thiomethyl, methylsulfinyl, methylsulfonyloxy, trifluoromethoxy, difluoromethoxy, difluorochloromethoxy, difluorochloromethyl or nitro; R3 is hydrogen, methyl, methoxy, ethoxy, fluorine, chlorine or thiomethyl; W is hydrogen or chlorine and Z is CH or N and their agriculturally utilizable salts are described.
Patent DK-0644317-T3 (DK)
Inventor: DOMAGALLA KLAUS DIPL-ING
IPC: F04C19/00
Filed: 1994-04-20
Granted: 1997-09-22
Abstract: Single-stage liquid-ring gas pump that can be flanged to a drive unit. The inlet and discharge connections are provided on a connection housing (3) which is intended for connection to the drive unit. Provided on that side of the connection housing which is remote from the drive are a control plate (4) and a working-space housing (5) with an impeller (14) revolving therein. The said impeller interacts in a sealing manner on its open side with the control plate and on its largely closed side (19) with an end wall (7) of the working-space housing (5). The working-space housing is designed as a deep-drawn sheet-metal part and has no medium connections. For connection with the connection housing or the control plate, it is provided with a radial connecting flange (6). The transition from the cylindrical part to the connecting flange (6) of the working-space housing (5) is rounded in such a way on the inside that the gap remaining between this rounding and the control plate remains below a certain size. Its incircle should not be larger than 3.5% of the impeller diameter. <IMAGE>
Patent DK-0629635-T3 (DK)
Inventor: TEUTSCH JEAN-GEORGES
IPC: A61P5/30
Filed: 1994-06-16
Granted: 1997-09-22
Abstract: The compounds of formula (I): <IMAGE>  in which,     R17 and R'17 are such that:     - either R17 and R'17 together form a ketone - or R17 represents a hydroxyl radical or an acyloxy radical and R'17 represents a hydrogen atom or an alkyl, alkenyl or alkynyl radical,   R3 represents a hydrogen atom, an alkyl radical or an acyl radical,    R1 and R2, which may be identical or different, represent     - a hydrogen atom,   - an alkyl radical, which is optionally substituted,   - an acyl radical,   - an aryl or aralkyl radical, which is optionally substituted, - an alkyl, aralkyl or arylcarbamoyl radical, which is optionally substituted, - or form, with the nitrogen atom to which they are attached, a saturated heterocycle which may contain a second hetero atom chosen from N, O and S and which may be substituted,   - or form a dialkylaminomethylene radical,    n is at most equal to 18, and the addition salts of the latter, their preparation, their application as medicaments, the compositions containing them and the new intermediates obtained.
Patent DK-0684945-T3 (DK)
Inventor: SLISKOVIC DRAGO ROBERT
IPC: C07D233/88
Filed: 1994-02-08
Granted: 2002-11-18
Abstract: Pharmaceutically useful compounds having ACAT inhibitory activity of the formula <CHEM> wherein n is 0, 1, or 2, for X other than tetrazole and n = 2 then R2 = R3 = H; R1 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, a heteroaromatic group or a hydrocarbon group having from one to 18 carbon atoms; R2 and R3 are hydrogen, halo, hydroxy, alkyl, alkenyl, cycloalkyl, phenyl, substituted phenyl, a heteroaryl, or form a spiroalkyl group; x is a 5-membered heteromonocyclic group containing at least one to four heteroatoms selected from the group consisting of isothiazole, oxazole, thiazole, imidazole, furan, thiophene, pyrrole, tetrazole, 1,2,3-triazole, 1,2,4-oxadiazole, 1,3,4-oxadiazole, 1,3,4-thiadiazole, 1,2,4-triazole, and 1,2,4-oxadiazole said heteromonocyclic group being unsubstituted or substituted at any available position along the ring,
Patent DK-0712838-T3 (DK)
Inventor: HIRAYAMA RYOICHI
IPC: C07C259/06
Filed: 1994-08-03
Granted: 1999-07-19
Abstract: An acylphenylglycine derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, and a preventive and remedy for diseases caused by an increased collagenase activity containing the same as the active ingredient, wherein R<1> represents hydrogen atom, methyl, methylaminomethyl or morpholinomethyl; R<2> represents hydrogen atom, hydroxy, fluorine atom, or C1-C4 linear or branched alkyl; and R<3> represents C1-C4 linear or branched alkyl. The compound (I) and the salt maintains a potent collagenase inhibitor activity in the blood for long after being administered, and are useful as a remedy for various diseases believed to be caused by an increased collagenase activity. <CHEM>   <IMAGE>
Patent DK-0752081-T3 (DK)
Inventor: ROSENGREN LARS
IPC: F21V19/00
Filed: 1995-03-14
Granted: 2000-08-14
Abstract: The present invention is for a lighting device by which a controlled light pattern is obtained from a specific light source. The device comprises a light source which emits several parallel light beams. There is one prism (3) for each light beam (8), which passes through the lighting device. All of the prisms are integrated parts of a common disc. Preferrably the light source comprises several light emitting diodes (1) each emitting one light beam. The prisms are suitably made as straight, circular cylinders, at least those parts thereof which protrude from the common disc. The oblique surface may be freely varied at both its angle at the axis of the cylinder and direction whereby the direction of the corresponding light beam may be controlled.
Patent DK-0800539-T3 (DK)
Inventor: HILGERS LUUK
IPC: A61K47/36
Filed: 1995-12-21
Granted: 2003-12-08
Abstract: Vaccine adjuvants comprising a sulpholipid polysaccharide in combination with an interface-forming constituent. The invention also provides a method for preparing a vaccine by emulsifying an aqueous solution of an antigen and a sulpholipid polysaccharide. The adjuvants are stable at high temperatures, and are at least as effective as conventional adjuvants. Their local toxicity, i.e. their reactogenicity, is generally lower than that of conventional adjuvants.
Patent DK-0882136-T3 (DK)
Inventor: YESAIR DAVID W
IPC: C07F9/10
Filed: 1997-01-31
Granted: 2002-08-12
Abstract: Methods for making lysophosphatidylcholine are provided, comprising hydrolysis of a mixture of phosphatidylcholine and an agent with phospholipase A2. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine, monoglyceride and fatty acid.
Patent DK-0914114-T3 (DK)
Inventor: DOLOVICH JERRY
IPC: A61K39/00
Filed: 1997-05-08
Granted: 2003-10-20
Abstract: Methods and compositions for treating type I immunoglobin E (IgE)-dependent hypersensitivity by the administration of monophosphoryl lipid A (MLA) or 3-deacylated monophosphoryl lipid A (3D-MLA) are disclosed. MLA or 3D-MLA administered alone or in combination with an allergen to a patient suffering from type I hypersensitivity reduces levels of total or allergen specific IgE and increases levels of IgG antibody in that patient. MLA and 3D-MLA can be administered as part of a desensitization regimen or as a component of a prophylactic vaccine to prevent a type I hypersensitivity reaction.
Patent DK-0919832-T3 (DK)
Inventor: OHTSUKI SHIGEO
IPC: G01S15/89
Filed: 1998-09-30
Granted: 2005-09-26
Abstract: A flow display method enabling the state of flows in a plane to be grasped together with inflow into and outflow from that plane. A Doppler method, for example, is used to obtain a velocity profile at each point in a planar area (100) of interest defined in a three-dimensional flow. A flow rate profile in the planar area (100) is found on the basis of the thus obtained velocity profile. From the flow rate profile and the velocity profile there are determined source points (12) representative of inflow into the planar area (100) and sink points (14) representative of outflow therefrom. Contour lines in the flow rate profile then join the source points (12) and the sink points (14) to obtain a display of planar streamlines (10). <IMAGE>
Patent DK-0965157-T3 (DK)
Inventor: FLADUNG MANFRED
IPC: B65H75/38
Filed: 1998-03-06
Granted: 2002-05-21
Abstract: PCT No. PCT/EP98/01309 Sec. 371 Date Sep. 3, 1999 Sec. 102(e) Date Sep. 3, 1999 PCT Filed Mar. 6, 1998 PCT Pub. No. WO98/39829 PCT Pub. Date Sep. 11, 1998A device for taking-up or stowing a cable (16, 64) with several leads (36), including a take-up drum (18, 60) which rotates around an axle (30, 38) to take up the cable is disclosed. The leads of the cable are connected to a first connection device (38). This first connection device also provides an electrically conductive connection to the lines of a supply. In order to prevent the leads of the cable from breaking when the drum rotates, the first connection device should be connected to the drum and should have first electrical contacts (50, 56) located on circuits which run coaxially to the drum axle and are connected to the leads (36) of the cable. The electrical lines leading to the supply should be connected to a second connection device (48) which can be shifted axially along the drum axle and should have second electrical contacts (56, 50) which form an electrically conductive connection with the first electrical contacts (56, 50).
Patent DK-0990365-T3 (DK)
Inventor: GORSUCH THOMAS E
IPC: H04J13/18
Filed: 1998-06-18
Granted: 2003-05-05
Abstract: A technique for transmission of wireless signals across CDMA radio links. Bandwidth is allocated dynamically within a session to specific CDMA subscriber unit based upon data rate determinations. Specifically, a dynamic bandwidth allocation algorithm operates from limits calculated based upon available ports per subscriber, expected user bandwidth, and parallel user bandwidth versus throughput. Provisions for priority service, unbalanced forward and reverse spectrum utilization, voice prioritization, and band switching are also made.