baber/WOPTO huggingface dataset:
Patent WO-2019227106-A1 (WO)
Title: Tumor-specific neoantigens and methods of using the same
Inventor: DUPERRET ELIZABETH KENNEDY
IPC: C12N15/62
Filed: 2019-05-28
Abstract: The disclosure relates to methods of manufacturing individualized vaccines that comprise nucleic acid molecules that encode one or more neoantigens specific for antigens that are expressed by a tumor in a subject. Compositions comprising coding regions encoding neoantigens organized in a pattern of nucleic acid sequences are also disclosed as well as methods of immunizing a subject using the same.
Patent WO-2019232350-A1 (WO)
Title: System and method for configuring an extender device
Inventor: CHARI AMALAVOYAL NARASIMHA
IPC: H04W12/08
Filed: 2019-05-31
Abstract: Many customers have difficulty setting up a new extender device in the customer premises environment to improve their multimedia service. Some embodiments include configuring an extender device based on existing WiFi network credentials to minimize errors. Some embodiments include an application for mobile devices that may enable the transfer of network credentials from existing multimedia devices on the WiFi network to configure a new extender device in real time. For example, the configuration may be based on a customer account, a corresponding environment, and corresponding multimedia devices associated with the customer account. The extender device may be configured with the network credentials (e.g., a WiFi service set identifier (SSID) and password) that is common to the corresponding multimedia devices associated with the customer account.
Patent WO-2019232381-A1 (WO)
Title: Simplified biosample processing for lc-ms/ms
Inventor: SHUFORD CHRISTOPHER MICHAEL
IPC: G01N33/487
Filed: 2019-05-31
Abstract: Disclosed are methods and systems using liquid chromatography/tandem mass spectrometry (LC-MS/MS) for the analysis of endogenous biomarkers isolated from biological samples. In certain embodiments, the samples comprise dried body fluids such as dried plasma.
Patent WO-2019236483-A1 (WO)
Title: Spirocyclic compounds
Inventor: DEY FABIAN
IPC: C07D498/10
Filed: 2019-06-03
Abstract: The present invention provides compounds and intermediates. The present invention also provides compounds which bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and their use for the treatment of abnormal cellular proliferation. The present invention also provides compounds that may be used as synthetic intermediates in the synthesis of bifunctional compounds used for targeted protein degradation.
Patent WO-2019245844-A1 (WO)
Title: Systèmes et procédés de dispositifs de sécurité destinés à être utilisés sur une plateforme de sécurité
Inventor: POCHTAR VITALII
IPC: G08B21/02
Filed: 2019-06-13
Abstract: Selon des modes de réalisation, l'invention concerne des systèmes et des procédés se rapportant à des dispositifs de sécurité (102A) qui peuvent détecter un vol potentiel d'objets précieux ou importants. Dans certains modes de réalisation, le dispositif de sécurité peut être intégré ou fixé à un objet d'intérêt (214) et fournir des notifications concernant un contact non autorisé avec l'objet (ou un contact avec un objet contenant qui inclut l'objet) et le fait que l'objet soit emporté. Lorsqu'un tel vol non autorisé se produit, dans certains modes de réalisation, le dispositif de sécurité (102A) peut fournir une notification, telle qu'une notification visuelle, une notification auditive ou une notification tactile.
Patent WO-2019246337-A1 (WO)
Inventor: WELKER DAVID JAMES
IPC: G02B1/04
Filed: 2019-06-20
Abstract: A method of making a waveguiding optical component includes processing a polymer optical material to form a billet having an axis of light transmission and having residual stress maintaining a transverse extent of the billet; placing the billet into a mold, the mold being configured to constrain transverse expansion of the billet according to a desired shape of the waveguiding optical component; and heating the billet in the mold to induce relaxation of the residual stress and corresponding transverse expansion of the billet, thereby forming the billet into the waveguiding optical component with the desired shape. An alternative method begins with a collection of individual canes or fiber segments which are fused during the heating process, bypassing a separate process of forming a billet.
Patent WO-2019246442-A1 (WO)
Inventor: BADYLAK STEPHEN FRANCIS
IPC: A61L24/10
Filed: 2019-06-20
Abstract: Methods are disclosed for dissecting a mucosa and a submucosa from a muscularis propria from a region of an esophagus of a subject. These methods include injecting submucosally into the esophagus of the subject a pharmaceutical composition comprising an extracellular matrix (ECM) hydrogel to form a cushion between the submucosa and the underlying muscularis propria at the region of the esophagus, wherein the ECM hydrogel has the following characteristics: a) a time to 50% gelation of less than 30 minutes at a temperature of about 37°C; b) a flow viscosity suitable for infusion into the esophagus; and c) a stiffness of about 10 to about 400 Pascal (Pa). The ECM hydrogel is not a urinary bladder ECM hydrogel.
Patent WO-2020033229-A1 (WO)
Title: Sequential detection based classifications of rfid tags in three-dimensional space
Inventor: TRAN QUOC-HUY
IPC: G06K19/07
Filed: 2019-08-01
Abstract: Systems and methods for sequential detection-based classifications of radio-frequency identification (RFID) tags in three-dimensional space are provided. The methods include modeling (510) a response from RFID tags as a probabilistic macro-channel and interrogating (520) an RFID tag by transmitting a series of packets. Each packet is a transmit symbol and a first series of packet is a transmitted codeword. The method includes receiving (530), from the RFID tag, a second series of packets that is a received codeword in response to the transmitted codeword and finding (540) a jointly typical transmit and receive codeword across all classes of macro-channels. The method also includes declaring (550) a class of the RFID tag based on a largest likelihood between the transmitted codeword and the received codeword.
Patent WO-2020028745-A1 (WO)
Inventor: SILVER RANDI B
IPC: A61K38/18
Filed: 2019-08-02
Abstract: La présente invention concerne des procédés de réduction de l'abondance du collagène cicatriciel, de la largeur de cicatrice et de la contracture du tissu cicatriciel, comprenant l'administration à un sujet ayant besoin d'un tel traitement d'une quantité efficace d'un stabilisateur de mastocytes, ou une quantité efficace d'un inhibiteur de domaine de HIF prolyl hydroxylase, ou une quantité efficace d'une combinaison d'un stabilisateur de mastocytes et d'un inhibiteur de domaine de HIF prolyl hydroxylase.
Patent WO-2020033801-A1 (WO)
Title: User equipment assisted inter-sector interference avoidance
Inventor: RYU JUNG HO
IPC: H04B7/06
Filed: 2019-08-09
Abstract: Certain aspects of the present disclosure provide techniques for reducing inter-sector interference. A method generally includes transmitting, in a multi-user multiple-input and multiple-output (MU-MIMO) mode, first beamformed transmissions using a first beam to a first user equipment (UE) in a first sector and second beamformed transmissions using a second beam to a second UE in a second sector, wherein the BS is configured to control a plurality of sectors comprising the first sector and the second sector, receiving, from the first UE, a feedback report indicating inter-sector interference encountered by the first UE in the first sector due to the second beamformed transmissions, and taking one or more actions based on the feedback report to reduce the inter-sector interference encountered by the first UE in the first sector.
Patent WO-2020046884-A1 (WO)
Inventor: SEO CHANG
IPC: F25D3/12
Filed: 2019-08-27
Abstract: This invention relates to a novel two-stage dry ice system for preserving perishable items (101, 102) during transport and methods thereof. The improved two-stage dry ice system includes dry ice (111) and a phase change material (110) specifically configured within a single and continuous holding volume with perishable items. Preservation of the perishable items for extended durations in comparison to other refrigeration techniques can be achieved.
Patent WO-2020047260-A1 (WO)
Inventor: WAHL DANIEL
IPC: C12Q1/6886
Filed: 2019-08-29
Abstract: Methods of treating a tumor in a subject are provided herein. In exemplary embodiments, the method comprises measuring the expression level of MGMT, GPRASP1, CHGA, MAPK8, ATP6V0A2, or FGF7, or any combination thereof, in a sample comprising a cell or cells from the tumor, and administering to the subject an alkylating chemotherapy, radiation therapy, or a combination comprising alkylating chemotherapy and radiation therapy, depending on the expression level(s). Related methods, kits, systems, computer-readable storage media, and methods implemented by a processor in a computer are further provided herein.
Patent WO-2020056310-A1 (WO)
Title: Reflective euv mask absorber manipulation to improve wafer contrast
Inventor: MELVIN III LAWRENCE S
IPC: G03F1/70
Filed: 2019-09-13
Abstract: Techniques and systems for improving wafer contrast by manipulating reflective extreme ultraviolet (EUV) mask absorber are described. Some embodiment disclosed herein provide for EUV absorber material, which transmits some EUV illumination, to suppress the printing of sub resolution assist features (SRAFs) while making the SRAFs closer in size to the printed feature by thinning the SRAF absorber thickness from the nominal mask absorber thickness in the bright-field mask case. In the dark-field mask case, a layer of absorber material is left in the SRAF trenches to prevent SRAF printing.
Patent WO-2020072979-A1 (WO)
Title: Slurry and solution compositions
Inventor: VELIS CHRISTOPHER
IPC: A61K47/10
Filed: 2019-10-04
Abstract: Slurries comprise liquid water, about 2% to about 70% ice by volume, and one or more additives affecting flowability and/or tonicity of the slurry. Solutions for making a slurry comprise liquid water and one or more additives affecting flowability of the slurry. Flowability of the slurry relates to ice particles capable of flowing through a cannula, such as a needle. The slurry is suitable for injection into subcutaneous fat of a human subject for removal of adipose tissue.
Patent WO-2020076891-A1 (WO)
Inventor: SHERMAN ANDREW J
IPC: H01F1/03
Filed: 2019-10-09
Abstract: A high saturation, low loss magnetic material suitable for high frequency electrical devices, including power converters, transformers, solenoids, motors, and other such devices.
Patent WO-2020092016-A1 (WO)
Inventor: FLIRI ANTON
IPC: A61K31/381
Filed: 2019-10-18
Abstract: The present disclosure relates to pharmaceutical compositions, pharmaceutical combinations and methods of treatment including zileuton, edaravone and atorvastatin compounds combined with nephrotoxicity-inducing antibiotic or anticancer drugs for treating bacterial infections and cancers.
Patent WO-2021080595-A1 (WO)
Title: Loudspeaker system layout for generating low frequency audio outputs in individual sound zones
Inventor: CAI TINGLI
IPC: H04R5/02
Filed: 2019-10-25
Abstract: In at least one embodiment, a loudspeaker arrangement for a vehicle is provided. The loudspeaker arrangement includes a surround sound loudspeaker arrangement and at least one proximity woofer. The surround sound loudspeaker arrangement includes a plurality of surround woofers being positioned in a listening environment in the vehicle that defines a plurality of sounds zones to provide a first low frequency audio output having a first sound pressure level within the vehicle. The at least one proximity woofer is positioned about a first seat in a first sound zone of the vehicle, the at least one proximity woofer being configured to provide a second low frequency audio output in the first sound zone of the vehicle. The second low frequency audio output as provided by the at least one proximity woofer modifies the first sound pressure level to provide a target sound pressure level.
Patent WO-2020097052-A1 (WO)
Title: Cartridges for vaporizer devices
Inventor: ROSSER CHRISTOPHER JAMES
IPC: A24F40/42
Filed: 2019-11-05
Abstract: Cartridges for vaporizer devices are provided. In one exemplary embodiment, the cartridge (200) can include a reservoir housing (202) having a storage chamber (204) and a dispensing (chamber206), and a vaporization chamber (208) in communication with the dispensing chamber. The storage chamber is configured to hold a first fraction of a vaporizable material and the dispensing chamber is configured to hold a second fraction of the vaporizable material. The dispensing chamber is further configured to selectively dispense at least a first portion of the second fraction of the vaporizable material through at least one dispense opening (218) in response to generation of one or more pressure pulses created within the dispensing chamber. The vaporizable chamber is configured to receive the dispensed vaporizable material from the dispensing chamber for vaporization by a first heating element (214) to form a vaporized material. Vaporizer devices are also provided.
Patent WO-2020101977-A1 (WO)
Title: Lipid ether amine compounds for topical treatment of cutaneous disease
Inventor: SVETLOV ARTEM
IPC: A61K9/06
Filed: 2019-11-06
Abstract: The present invention provides a topical treatment compound to treat a variety of cutaneous diseases, such as skin cancer, psoriasis, atopic dermatitis, and wounds. This topical treatment is comprised of a lipid ether amine compound and a vehicle for topical administration, such as a cream, ointment, or spray. This combination can then be topically applied to the afflicted cutaneous disease area on a medical patient. This lipid ether amine compound has shown great effectiveness in treating tumorigenesis in mice and current treatments for humans have lacked the topical application and effectiveness necessary to treat some of these cutaneous diseases that have previously lacked an option for treatment. In other embodiments, the present invention provides a treatment compound to treat infection by microbes with administration by different routes including topical and intravenous.
Patent WO-2020102440-A1 (WO)
Inventor: RODRIGUEZ JORGE
IPC: H01R31/08
Filed: 2019-11-13
Abstract: An interconnect is disclosed that opens a battery circuit when an access cover is removed. The interconnect includes a single installed position, and does not include any throw positions to avoid ambiguity. The interconnect includes a conductive element that closes the battery circuit when the interconnect is installed. The access cover cannot be removed when the interconnect is installed, because the interconnect includes at least one mechanical feature that prevents removal of the access cover. In some instances, the interconnect is integrated into the access cover, such that when the cover is removed, the circuit is opened necessarily during removal. The interconnect interface may include blades, pins, or other electrically conducting elements. The interconnect is arranged in the battery system away from power electronics and other components that may interface to an electrical load, thus providing an added measure of safety when the access cover is off.
Patent WO-2020117577-A1 (WO)
Title: Superconducting circuit and method for detecting a rising edge of an input signal
Inventor: BRAUN ALEXANDER L
IPC: H03K3/38
Filed: 2019-11-27
Abstract: Superconducting circuits and methods for detecting a rising edge of an input signal are described. An example superconducting circuit includes an input terminal for receiving an input signal comprising both positive pulses and negative pulses. The superconducting circuit further includes a first stage, coupled to the input terminal and a first node, configured to suppress both any backward propagating negative pulses and any forward propagating negative pulses, and allow propagation of any forward propagating positive pulses. The superconducting circuit further includes a second stage, coupled to the first node, configured to store a forward propagating positive pulse and reflect a stored positive pulse back to the first node as a negative pulse such that in response to each rising edge of the input signal a return-to-zero signal comprising both a rising edge and a falling edge is provided as an output at the first node.
Patent WO-2020113095-A1 (WO)
Inventor: GIDNEY CRAIG
IPC: G06N10/00
Filed: 2019-11-27
Abstract: Methods, systems, and apparatus for producing CCZ states and T states. In one aspect, a method for distilling a CCZ state includes preparing multiple target qubits, ancilla qubits and stabilizer qubits in a zero state, performing an X gate for each stabilizer qubit on multiple ancilla qubits or multiple ancilla qubits and one of the target qubits using the stabilizer qubit as a control, measuring the stabilizer qubits, performing, on each of the ancilla qubits, a Z 1/4  gate and a Hadamard gate, measuring each of the ancilla qubits, performing, conditioned on each measured ancilla qubit state, a NOT operation on a selected stabilizer qubit, or a NOT operation on the selected stabilizer qubit and a Z gate on one or more respective target qubits, performing, on each target qubit and conditioned on a measured state of a respective stabilizer qubit, a Z gate on the target qubit, and performing an X gate on each of the target qubits.
Patent WO-2020123607-A1 (WO)
Title: Compositions, devices, and methods for treating or preventing headaches
Inventor: KOLLINS JOHN
IPC: A61P25/06
Filed: 2019-12-11
Abstract: Disclosed herein are pharmaceutical compositions, devices, their combinations, and their uses thereof for example in treating or preventing headaches. The present disclosure provides new methods of medical treatment or prevention (e.g, for headaches) resulting in unexpected superior pharmacokinetics compared to conventional methods. In some instances, the methods herein can produce a unique pharmacokinetic profile of a metabolite.
Patent WO-2020123768-A1 (WO)
Inventor: ALTHENAYAN FAISAL
IPC: C07C29/04
Filed: 2019-12-12
Abstract: L'invention concerne un procédé de production séparée de tert-butanol et de sec-butanol, comprenant les étapes consistant à introduire un courant de butènes mélangés sur un côté tube d'un ensemble membrane de réaction, introduire une alimentation en eau de réacteur de TBA sur le côté tube de l'ensemble membrane de réaction, introduire un gaz de balayage sur un côté coque de l'ensemble membrane de réaction, introduire une alimentation en eau de réacteur de SBA sur le côté coque, laisser le courant de butènes mélangés venir en contact avec le côté tube de sorte que les gaz sélectifs dans le flux de butènes mélangés s'écoulent à travers la membrane jusqu'au côté coque, laisser les gaz sélectifs qui s'écoulent à travers la membrane réagir avec l'eau pour produire du sec-butanol, laisser des gaz de rétentat qui ne parviennent pas à traverser la membrane réagir avec l'eau pour produire du tert-butanol, collecter le tert-butanol dans un effluent de réacteur de TBA et collecter le sec-butanol dans un effluent de réacteur de SBA.
Patent WO-2020123845-A1 (WO)
Title: Procédés pour augmenter la productivité d'une cellule fongique filamenteuse dans la production d'un polypeptide
Inventor: MAIYURAN SUCHINDRA
IPC: C07K14/37
Filed: 2019-12-12
Abstract: La présente invention concerne un mutant d'une cellule fongique filamenteuse mère, comprenant une séquence codante d'un polypeptide d'intérêt sous le contrôle transcriptionnel d'un promoteur régulé par un facteur de transcription, le gène codant pour le facteur de transcription étant modifié dans la cellule fongique filamenteuse mère pour produire le mutant, rendant le mutant déficient dans la production du facteur de transcription, ce qui augmente la productivité du mutant dans la production du polypeptide d'intérêt, et/ou réduit ou élimine le phénotype cellulase-négatif dans le mutant résultant. La présente invention concerne également un procédé de construction d'un tel mutant et un procédé de production d'un polypeptide d'intérêt avec un tel mutant.
Patent WO-2020142295-A1 (WO)
Title: Virtual try-on systems and methods for spectacles
Inventor: GOLDBERG DAVID
IPC: G06T19/00
Filed: 2019-12-21
Abstract: Various aspects of the subject technology relate to systems, methods, and machine-readable media for virtual try-on of items such as spectacles. A virtual try-on interface may be implemented at a server or at a user device, and may use collision detection between three-dimensional models of the spectacles and of a user's face and head to determine the correct size and position of the spectacles for virtual try-on. With the determined size and position, a virtual representation of the spectacles is superimposed on an image of the user.
Patent WO-2020154393-A1 (WO)
Title: Détection tactile basée sur la lumière avec sensibilité directionnelle
Inventor: KU PEI-CHENG
IPC: G01L1/22
Filed: 2020-01-22
Abstract: L'invention concerne un dispositif comprenant un substrat et un ensemble de capteurs de force supporté par le substrat. Chaque capteur de force comprend une colonne s'étendant vers l'extérieur à partir du substrat, chaque colonne comprenant un empilement de couches semi-conductrices, l'empilement de couches semi-conductrices étant configuré pour émettre de la lumière lors de la polarisation de l'empilement de couches semi-conductrices, et une borne disposée le long d'une partie seulement d'un périmètre de la colonne de telle sorte que, pris ensemble, la colonne et la borne ont une forme de section transversale asymétrique. Chaque colonne possède une section transversale allongée le long d'un axe. Une orientation de l'axe et une position périphérique de la partie du périmètre à laquelle la borne est disposée diffèrent de part et d'autre de l'ensemble de capteurs de force de telle sorte qu'une variation de la lumière émise par l'empilement de couches semi-conductrices d'un ou de plusieurs des capteurs de force est indicative d'une direction d'une force de cisaillement appliquée à l'ensemble de capteurs de force.
Patent WO-2020171971-A1 (WO)
Inventor: FOX SETH
IPC: G06F40/197
Filed: 2020-02-07
Abstract: A computing device identifies detects changes to a shared document from a plurality of users. The computing device determines change activities and corresponding provenance to the shared document in response to detecting the changes. A context of granular changes is generated based on the change activities and corresponding provenance to the shared document. The computing device generates a graphical user interface based on the context. The graphical user interface provides a visualization of the granular changes.
Patent WO-2020172545-A1 (WO)
Title: Dispositif d'affichage multiple à modulateur spatial de lumière angulaire
Inventor: HELLMAN BRANDO
IPC: H04N13/365
Filed: 2020-02-21
Abstract: L'invention concerne un système de projection de lumière permettant de projeter des images haute résolution et de haute qualité dans différentes directions. Le système comprend une source de lumière conçue pour fournir un faisceau de lumière de sortie homogène et un élément optique de mise en forme d'éclairage configuré avec au moins un élément parmi un angle de cône prédéterminé, une ouverture numérique et un nombre F. Le système comprend également un modulateur de lumière angulaire (MLA) spatialement dépendant et doté d'une pluralité de pixels, chaque pixel ayant un état MARCHE, un état ARRÊT, une pupille d'entrée et N pupilles d'ordre de diffraction. Le MLA est positionné de telle sorte que le faisceau de sortie est incident sur la pluralité de pixels. Le ou les éléments parmi l'angle de cône prédéterminé, l'ouverture numérique et le nombre F des éléments optiques de mise en forme d'éclairage empêchent que de la lumière contaminante n'entre dans une mauvaise pupille. Le système comprend en outre un processeur couplé au MLA pour fournir une orientation de faisceau basée sur la diffraction discrète, permettant au MLA de projetter dans un ordre de diffraction à un moment.