baber/WOPTO huggingface dataset:
Patent MX-2020009617-A (MX)
Title: Mass spectrometric determination of testosterone in multiplexed patient samples.
Inventor: GOLDMAN SCOTT
IPC: G01N30/04
Filed: 2019-03-15
Abstract: Provided herein are methods for high throughput quantitation of testosterone utilizing at least two different derivatizing agents of different masses. In another aspect, provided herein are methods for determining the amount of testosterone in each of a plurality of human samples with a single mass spectrometric assay by subjecting each of a plurality of human samples to a different derivatizing agent to generate a differently derivatized testosterone in each of the plurality of samples; combining the plurality of samples to form a multiplex sample; and quantifying the amount of testosterone in each sample by mass spectrometry.
Patent MX-2020010800-A (MX)
Title: PHOTOPROTECTIVE COMPOSITIONS CONTAINING <i>MALASSEZIA</i>-DERIVED COMPOUNDS AND/OR CHEMICAL ANALOGS THEREOF.
Inventor: EINZIGER MICHAEL
IPC: C07D209/12
Filed: 2019-04-12
Abstract: The present invention relates to compounds, compositions, and methods for modulating skin pigmentation and treating or preventing UV-induced skin damage, erythema, aging of the skin, sunburn, and hyperpigmentation in a subject. The compounds, compositions, and methods of the present invention generally involve <i>Malassezia</i>-derived compounds, including malassezin and indirubin, and/or chemical analogs thereof. Other applications of the compounds and compositions disclosed herein include, but are not limited to, improving hyperpigmentation caused by a hyperpigmentation disorder, inducing melanocyte apoptosis, and modulating arylhydrocarbon receptor (AhR) activity, melanogenesis, melanin production, melanosome biogenesis, melanosome transfer, melanocyte activity, and melanin concentration.
Patent MX-2020011776-A (MX)
Title: Stackable container.
Inventor: SOSTMANN RÜDIGER
IPC: B65D81/26
Filed: 2019-04-11
Abstract: The invention relates to a stackable container (1), which comprises a step-like edge at upper ends of the side walls (2), and, on the outer side of the side walls, a projection (2d, 2e), which stands on the step-like edge. A plurality of openings (4, 4a) on the lower edges of the side walls open into a collecting channel (3b, 3c) extending along the base (3), which is formed in one piece with the base. Small quantities of liquids which emerge through the openings are collected in the collecting channel. The projection covers the collecting channel and, together with the outer wall of the collecting channel and the step-like edge of the lower upright container, form a clearance, into which larger quantities of liquids can enter and flow into the lower container. Extinguishing water, which is sprayed over the stack of containers in the event of a fire, can thus pass from the upper container into the lower containers of the stack as well and also extinguish a fire in a lower region of the stack.
Patent MX-2020012062-A (MX)
Title: Four ways circuit breaker.
Inventor: ROCERETO PIETRO
IPC: H01H13/60
Filed: 2019-04-08
Abstract: An inverter circuit breaker (100) comprising: - a case (20,21) and a button (30) movable with respect to the case (20,21); - four connecting terminals (81-84); - a rocking control member (50) adapted to be rotated in two opposite directions about one first rotation axis (al) by means of the button (30); - a rotor (60) adapted to be rotated in two opposite directions by the rocking control member (50) about a second rotation axis (a2) perpendicular to the first rotation axis (al); - two rocking switching members (72,73), adapted to be rotated simultaneously by the rotor (60) for establishing and interrupting bridges between connecting terminal pairs.
Patent MX-2020012208-A (MX)
Title: Generation of knock-out primary and expanded human nk cells using cas9 ribonucleoproteins.
Inventor: LEE DEAN ANTHONY
IPC: A61K38/46
Filed: 2019-05-16
Abstract: Disclosed are compositions and methods for genetically engineering NK cells.
Patent MX-2021000489-A (MX)
Title: Display panel, display device, and driving method.
Inventor: HUANG YAO
IPC: G09G3/3225
Filed: 2019-07-01
Abstract: A display panel, a display device, and a driving method. The display panel comprises a plurality of display areas; the plurality of display areas comprise a first display area and a second display area that are parallel to each other but do not overlap; the first display area comprises a plurality of rows of first pixel units that are arranged in an array; the second display area comprises a plurality of rows of second pixel units that are arranged in an array; the display panel further comprises a first light-emitting control scanning drive circuit for controlling the plurality of rows of first pixel units to emit light, and a second light-emitting control scanning drive circuit for controlling the plurality of rows of second pixel units to emit light. The driving method comprises: providing a first starting signal to the first light-emitting control scanning drive circuit, and providing a second starting signal to the second light-emitting control scanning drive circuit, wherein the second starting signal and the first starting signal are separately independently applied.
Patent MX-2021001009-A (MX)
Title: Compositions and methods for tcr reprogramming using target specific fusion proteins.
Inventor: DING JIAN
IPC: A61K35/17
Filed: 2019-07-26
Abstract: Provided herein are T cell receptor (TCR) fusion proteins (TFPs), T cells engineered to express one or more MUC16 or IL13RÎ±2 or MSLN TFPs, and methods of use thereof for the treatment of diseases, including cancer.
Patent MX-2021001441-A (MX)
Title: A solid state form of pladienolide pyridine compounds and methods of use.
Inventor: ENDO ATSUSHI
IPC: C07D405/06
Filed: 2016-11-17
Abstract: The present disclosure provides a novel solid state form of pladienolide pyridine compounds, compositions comprising at least one such solid state form, and methods of preparation and use and the same. The novel solid state form of pladienolide pyridine compounds may be useful in the treatment of cancer, such as, for example, cancers in which agents that target the spliceosome and mutations therein are known to be useful.
Patent MX-2021001577-A (MX)
Title: Identifying two tunnels set up in one protocol data unit session.
Inventor: SHI NIANSHAN
IPC: H04W76/15
Filed: 2019-07-09
Abstract: A method, system and apparatus for identification of two tunnels that have been set up in one protocol data unit (PDU) session are disclosed. According to one aspect, a method implemented in a radio network node includes transmitting to a core network node a first message that includes a Transport Network Layer, TNL, address for a downlink tunnel. The method further includes receiving from the core network node a reply message that includes an uplink, UL, transport layer address corresponding to the TNL address for the downlink tunnel.
Patent MX-2021002474-A (MX)
Title: Chronic nightly dosing of lasmiditan for migraine prevention.
Inventor: JOHNSON KIRK WILLIS
IPC: A61P25/06
Filed: 2019-09-03
Abstract: The present invention relates to chronic nightly use of lasmiditan for the prevention of migraine, particularly therapy resistant migraine which is defined herein as migraine refractory to two or more prior monotherapy and/or dual therapy treatment or prevention regimens.
Patent MX-2021005737-A (MX)
Title: Current limiting circuit arrangement.
Inventor: JENSEN KRISTOPHOR RAY
IPC: H02H9/06
Filed: 2021-05-14
Abstract: A floating two-terminal unipolar current limiting circuit arrangement implemented with enhancement mode devices and bipolar devices with a unique voltage-current operation curve. This operation curve makes this device particularly advantageous to instrumentation systems that are intended to experience large voltage transients and long-term exposure to voltages that would normally damage measurement equipment. The present current limiting device is designed to have a large impedance value prior to a "turn-on" voltage, then quickly transitions to a low impedance state. When the conducted current exceeds a setpoint or a high-voltage event occurs, the current limiting device further transitions to the "cutoff' region, which transition resumes the initial high-impedance state. In one embodiment the threshold current may be set with internal components, while a further embodiment allows the current setpoint to be set by external components. The current limiting device designs according to the present embodiments allow for series scaling and parallel scaling.
Patent MX-2021009335-A (MX)
Title: Drinking straw, package assembly and method for producing a drinking straw.
Inventor: MARTINI PIETRO
IPC: A47G21/18
Filed: 2020-01-30
Abstract: There is described a drinking straw (3, 3') for a package (2) being filled with a pourable food product. The drinking straw (3, 3') comprises at least an inlet opening (11) for allowing the introduction of the pourable food product into the drinking straw (3, 3'), a tubular main portion (16) configured to be inserted, in use, into the package (2), having the inlet opening (11) and a sleeve (22, 22') superimposed on and/or surrounding at least a section of the tubular main portion (16). The sleeve (22, 22') is configured to allow for the insertion and/or introduction of the drinking straw (3, 3') into the package (2) and to impede and/or hinder and/or block a removal and/or separation of the drinking straw (3, 3') from the package (2) after introduction and/or insertion of the drinking straw (3, 3') into the package (2).
Patent MX-2021009687-A (MX)
Title: Treatment of al amyloidosis with the combination of monoclonal antibodies against immunoglobulin light chains and the cd38 cell membrane molecule on antibody-producing and other immune cells.
Inventor: COMENZO RAYMOND
IPC: C07K16/28
Filed: 2019-12-16
Abstract: Treatment of AL Amyloidosis with the Combination of Monoclonal Antibodies against immunoglobulin Light Chains and Aggregates of Immunoglobulin Light Chains and the CD38 Cell Membrane Molecule on Antibody-Producing and Other Immune Cells.
Patent MX-2021011617-A (MX)
Title: Adaptive error correction in quantum computing.
Inventor: GUNNELS JOHN
IPC: G06N10/00
Filed: 2020-03-17
Abstract: A method for adaptive error correction in quantum computing includes executing a calibration operation on a set of qubits, the calibration operation determining an initial state of a quantum processor. In an embodiment, the method includes estimating, responsive to determining an initial state of the quantum processor, a runtime duration for a quantum circuit design corresponding to a quantum algorithm, the quantum processor configured to execute the quantum circuit design. In an embodiment, the method includes computing an error scenario for the quantum circuit design. In an embodiment, the method includes selecting, using the error scenario and the initial state of the quantum processor, a quantum error correction approach for the quantum circuit design. In an embodiment, the method includes transforming the quantum algorithm into the quantum circuit design, the quantum circuit design including a set of quantum logic gates.
Patent MX-2021012091-A (MX)
Title: Method of training a neural network to reflect emotional perception, related system and method for categorizing and finding associated content and related digital media file embedded with a multi-dimensional property vector.
Inventor: LYSKE JOSEPH MICHAEL WILLIAM
IPC: G06F16/55
Filed: 2020-04-01
Abstract: A property vector representing extractable measurable properties, such as musical properties, of a file is mapped to semantic properties for the file. This is achieved by using artificial neural networks "ANNs" in which weights and biases are trained to align a distance dissimilarity measure in property space for pairwise comparative files back towards a corresponding semantic distance dissimilarity measure in semantic space for those same files. The result is that, once optimised, the ANNs can process any file, parsed with those properties, to identify other files sharing common traits reflective of emotional- perception, thereby rendering a more liable and true-to-life result of similarity/dissimilarity. This contrasts with simply training a neural network to consider extractable measurable properties that, in isolation, do not provide a reliable contextual relationship into the real-world.
Patent MX-2021014325-A (MX)
Title: Casting nozzle.
Inventor: RICHAUD JOHAN
IPC: B22D11/06
Filed: 2020-05-22
Abstract: A casting nozzle (10) for use in the casting of molten metal produces a stable flow pattern having an elongated section in the horizontal plane. The bore (12) cross-sectional area contains, from entry (24) to exit (26, 28), at least two significant section area reductions to reduce turbulence, realign streamlines and affect flow distribution inside the nozzle. The bore cross-section has a local minimum value in a contraction section (40) located between the entry section (30) and an expansion section (50). Bore cross-sectional area decreases from the expansion section to the lower end of the nozzle. The two significant cross-sectional area reductions cooperate with other structures within the bore to stabilize flow.
Patent MX-2022000174-A (MX)
Title: Monoclonal antibodies that bind egfrviii and their use.
Inventor: FITZGERALD DAVID JOSEPH
IPC: C07K16/28
Filed: 2020-07-01
Abstract: Disclosed are monoclonal antibodies and antigen binding fragments that specifically bind epidermal growth factor receptor (EGFR) variant (v) III, conjugates thereof, and chimeric antigen receptors. Nucleic acid molecules encoding the heavy and light chain domains of the antibodies, and the chimeric antigen receptors (CARs), are also disclosed, as are host cells expressing the nucleic acid molecules. In addition, disclosed is the use of these monoclonal antibodies, antigen binding fragments, conjugates, and T cells expressing the CARs, such as for the treatment of a tumor expressing EGFRvIII. Also disclosed are methods for detecting a tumor that expresses EGFRvIII.
Patent MX-2022000572-A (MX)
Title: Apparatus and method for exposure of relief precursors.
Inventor: LENSSENS PIETER
IPC: G03F7/20
Filed: 2020-07-14
Abstract: Apparatus for exposure of a relief precursor (P) which comprises a substrate layer and at least one photosensitive layer, said apparatus comprising: a carrying structure (10) for carrying a relief precursor; a LED array (20) configured to illuminate photosensitive layer of the relief precursor carried by the carrying structure, said LED array being configured to illuminate simultaneously a predetermined surface area of at least 900 cm2, said LED array comprising a plurality of subsets (25) of one or more LEDs (21), each subset being individually controllable; a control unit (40) to control the plurality of subsets (25) individually, and such that an irradiation intensity difference in the predetermined surface area is within a predetermin d range.
Patent MX-2022002767-A (MX)
Title: Nutritional supplements and methods of nutritional supplementation affecting mood and focus in children.
Inventor: TALBOTT SHAWN M
IPC: A23L33/105
Filed: 2020-09-04
Abstract: Nutritional supplements and methods of nutritional supplementation that affect focus and mental performance while supporting mood in subjects, including children, are provided. The supplements and methods of supplementation improve focus and/or mental performance by supporting both brain and gut health. In some instances, the nutritional supplements and methods of nutritional supplementation described affect both mood and focus in children simultaneously.
Patent MX-2022003288-A (MX)
Title: Treatment involving therapeutic antibody and interleukin-2 (il2).
Inventor: KREITER SEBASTIAN
IPC: A61K38/20
Filed: 2020-09-22
Abstract: Tumor cells often evade an immune response, e.g., by reducing or eliminating MHC expression and/or IFN-signaling, which enables uncontrolled growth. We demonstrate herein that antibody-based immunotherapy in combination with IL2 administration is an effective therapy against such resistant tumors. Specifically, the present disclosure relates to methods of treating a subject with cancer that is at least partially resistant to an MHC-dependent T cell response comprising administering to the subject: a. a polypeptide comprising IL2 or a functional variant thereof or a polynucleotide encoding a polypeptide comprising IL2 or a functional variant thereof; and b. antibody-based immunotherapy.
Patent MX-2022003323-A (MX)
Title: Central nervous system targeting polynucleotides.
Inventor: SAH DINAH WEN-YEE
IPC: C07K14/005
Filed: 2017-07-17
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding payloads for the treatment of CNS disorders.
Patent MX-2022003602-A (MX)
Title: Opening/closing device for a container for pourable products.
Inventor: SILLA ROBERTO
IPC: B65D5/74
Filed: 2020-09-24
Abstract: Opening/closing device (1) for a container (100) for pourable products having at least one pierceable portion (101), said opening/closing device comprising a collar (2) combinable with said container at said pierceable portion, a cap (3) provided with a lower portion (3a) and displaceable on the outer surface (2a) of said collar (2) in a constrained and only rotatable way by first guiding means (40) interposed between said collar (2) and said lower portion (3a), and a cutting element (5) movable in a constrained way inside said collar (2) by second guiding means (60), which are interposed between said cutting element (5) and said collar (2) to sever said pierceable portion, said device (1) further comprising pushing means (7) for said cutting element (5) which are driven by said cap (3), at least during its first displacement on said outer surface (2a) of said collar (2), such as to aid the displacement of said at least one cutting element inside said collar in direction of said pierceable portion, said cap (3) comprising at least one lid (3b) rotatably constrained with respect to said lower portion (3a) of said cap (3) between an opening position (PI) and a closing position (P2), and vice-versa, characterized by comprising rel easing/ engaging means (10) between said lid (3b) and said collar (2) such as to allow the opening/closing of said lid depending on the rotation angle reached by said cap (3) with respect to said collar (2), after the first displacement of said cap on said outer surface (2a) of said collar (2), said opening of the lid being allowed only when said cap reaches a rotation angle such as the pouring is handier for the user, and once the lid has been reclosed, said lied being lockable in stable position with the collar by rotating the cap with respect to the collar so that to reach a rotation angle different from that in which said lid is rotatable with respect to the lower portion of the cap.
Patent MX-2022005663-A (MX)
Title: Electroporation apparatus and method.
Inventor: REED THOMAS D
IPC: C12M1/32
Filed: 2020-11-11
Abstract: Electroporation is a technique in which an electrical field is applied to cells in order to increase the permeability of the cell membrane. This allows for chemicals, drugs, and/or macromolecules such as proteins and nucleic acids to be introduced into the cells. Embodiments relate to an electroporation apparatus. The electroporation apparatus comprises: a plurality of chambers configured to store a plurality of cells during an electroporation process; a plurality of electrodes configured to generate a plurality of electric fields within the plurality of chambers during the electroporation process, each electric field of the plurality of electric fields corresponding to one chamber of the plurality of chambers; a flow channel configured to transport the plurality cells during a cell collection process after the electroporation process; and a plurality of valves connecting the plurality of chambers to the flow channel.
Patent MX-2022006413-A (MX)
Title: A fluid-processing device for a beverage preparation machine.
Inventor: TALON CHRISTIAN
IPC: A47J31/40
Filed: 2020-12-01
Abstract: A fluid processing device (10) for a beverage preparation machine is described. The fluid processing device (10) is configured for processing a fluid substance to be introduced into a container (C) for the preparation of a beverage product by mixing of the fluid substance with an ingredient contained in the container (C). The fluid processing device (10) comprises a fluid processing body (12) provided with an inlet portion (14). The fluid processing body (12) comprises in turn at least one inlet means (18) for introducing the fluid substance into the container (C). The inlet means (18) is provided at the inlet portion (14) of the fluid processing body (12). The fluid processing body (12) also comprises an outlet portion (16) and at least one outlet means (20) for dispensing the beverage product from the container (C). The outlet means (20) is provided at the outlet portion (16) of the fluid processing body (12). Preferably, the fluid processing body (12) is a needle-shaped fluid processing body (12) comprising at least one end portion (26; 28) configured for perforating, piercing and/or tearing a specific portion or wall of the container (C) before the introduction of the fluid substance into the container (C).
Patent MX-2022008520-A (MX)
Title: Flush instrument with blood exposure protection and related methods.
Inventor: MA YIPING
IPC: A61M25/09
Filed: 2020-12-22
Abstract: A system (100) for accessing a patient's vascular system having a tube (110) with a wall (139) that defines an exterior surface (144) and lumen with a proximal end and a distal end, and a guidewire (112) that is deployable, by sliding distally, from a retracted position in which the guidewire resides in the lumen, to a deployed position in which the guidewire extends beyond the distal end. The system may further have a retraction mechanism (114) that can be actuated to retract the guidewire from the deployed position to the retracted position; alternatively a protective shield (1514) that can be actuated to extend distally from the distal end of the tube to cover the guidewire in the deployed position.
Patent MX-2022009382-A (MX)
Title: Self-cleaning, antiviral, bacteriostatic, and antibacterial mouth cover and its processing method by 3d printing.
Inventor: AGUSTÍN SERRANO RICARDO
IPC: A62B7/10
Filed: 2022-07-29
Abstract: The present relates to a face mask with the property of being bacteriostatic, self-cleaning, antibacterial, and antiviral. Also, regardless of the microorganism's size (bacteria, fungi, or viruses), it can be annihilated on its surface, recyclable, and multifunctional according to daily life uses. Said device has a dual exhalation and inhalation valve, a battery holder, and a self-adjusting system for all types of a face. Further, it includes a set of layers of different non-conductive and semi-conductive fabrics with a charging capacity of 6.6V or higher, thus filtering dust, bacteria, fungi, or viruses, used in surgical spaces or public spaces to meet the different needs of the user.
Patent MX-2022009974-A (MX)
Title: Tetrahydrocurcuminoid-metal complexes, manufacturing methods thereof, and uses thereof.
Inventor: DUBOURDIEU DANIEL J
IPC: A61K31/7135
Filed: 2021-05-13
Abstract: The invention is directed to tetrahydrocurcuminoid-metal complexes. The complexes can be included in compositions that further include additional nutraceutical antimicrobials, antioxidants, and immune boosters. The tetrahydrocurcuminoid-metal complexes can be administered to animals to increase animal health, reduce stress, reduce oxidative stress, maintain health, improve health, improve immunity, improve vaccination efficacy, increase feed conversion rate, decrease pro-inflammatory cytokine levels, or any combination thereof in an animal. The tetrahydrocurcuminoid-metal complexes of the invention exhibit enhanced bioavailability relative to the individual, non-complexed components.