baber/WOPTO huggingface dataset:
Patent BR-112023002520-A2 (BR)
Title: Glóbulos de resina, método para produzir glóbulos de resina e produto que utiliza glóbulos de resina
Inventor: TAKASHI ABE
IPC: A61K8/73
Filed: 2021-08-10
Abstract: GLÓBULOS DE RESINA, MÉTODO PARA PRODUZIR GLÓBULOS DE RESINA E PRODUTO QUE UTILIZA GLÓBULOS DE RESINA. A presente invenção proporciona glóbulos de resina que podem proporcionar vários tipos de produtos, como um cosmético tendo impressão tátil, capacidade de espalhar sobre a pele e transparência excelentes, que podem substituir as partículas de resina compostas por um material sintético derivado do petróleo, e que têm biodegradabilidade favorável, e a presente invenção também proporciona vários tipos de produtos, como um cosmético que utiliza os glóbulos de resina. Os glóbulos de resina são formados com uma resina contendo celulose como um componente principal. Os glóbulos de resina têm um tamanho de partícula cumulativo a 50%, em uma base de volume, de 50 µm ou menor, um grau de esfericidade de 0,7 a 1,0, um grau de lisura da superfície de 70 a 100%, um grau de solidez de 50 a 100%, e uma taxa de biodegradação por 5 dias, conforme medida de acordo com JIS K6950:2000 (ISO 14851:1999), de 20% ou mais, e o teor da celulose na resina é 90 a 100% em massa. Além disso, a presente invenção proporciona um produto de qualquer um de um cosmético, uma preparação dermatológica, uma tinta, um artigo moldado, um filme, um agente de revestimento e uma composição de resina, os quais contêm os glóbulos de resina.
Patent BR-112023003490-A2 (BR)
Title: Métodos para prevenção de embolização de cristais de colesterol com ciclodextrinas
Inventor: DIANA KERWIN
IPC: A61P3/06
Filed: 2021-08-27
Abstract: MÉTODOS PARA PREVENÇÃO DE EMBOLIZAÇÃO DE CRISTAIS DE COLESTEROL COM CICLODEXTRINAS. Trata-se de métodos para prevenir ou reduzir o risco de desenvolver e/ou prevenir ou reduzir o risco de um aumento em uma quantidade e/ou um tamanho, e/ou mudar o formato, de cristais de colesterol circulante (por exemplo, sangue, soro, plasma) (e/ou coágulos que compreendem cristais de colesterol) em um indivíduo. Além disso, são divulgados no presente documento métodos para prevenir ou reduzir o risco de embolização de cristais de colesterol (CCE) e/ou um sintoma dessa doença em um indivíduo. Os métodos envolvem geralmente administrar uma quantidade terapeuticamente eficaz de 2-hidroxipropipropil-beta-ciclodextrina ao indivíduo. No presente documento, também são fornecidas composições farmacêuticas que compreendem uma quantidade terapeuticamente eficaz de 2-hidroxipropipropil-beta-ciclodextrina e um excipiente farmaceuticamente aceitável.
Patent BR-112023004203-A2 (BR)
Title: Processo para produzir etilenoglicol e/ou propilenoglicol e/ou glicerol
Inventor: DAVIDE ANSOVINI
IPC: C07C29/132
Filed: 2021-09-27
Abstract: PROCESSO PARA PRODUZIR ETILENOGLICOL E/OU PROPILENOGLICOL E/OU GLICEROL. Um processo para produzir glicóis a partir de uma fonte de carboidrato usando um sistema catalisador, e cujo processo pode ser realizado continuamente em um reator, e em cujo processo um material catalisador é recuperado do efluente do reator. O efluente do reator é submetido à separação para obter alguns glicóis valiosos, e uma ou mais das correntes de fundo compreendendo polióis pesados e algum material catalisador contendo um ou mais compostos de tungstênio é submetido à queima, e o queimador faz parte de uma caldeira que pode gerar vapor. Tal vapor pode ser usado na separação de um ou mais dos compostos desejados.
Patent BR-112023004848-A2 (BR)
Title: Aparelho e método para aplicar reforço ao efetuador de extremidade de grampeador cirúrgico através de base fixa
Inventor: GREGORY J BAKOS
IPC: A61B17/072
Filed: 2021-09-14
Abstract: APARELHO E MÉTODO PARA APLICAR REFORÇO AO EFETUADOR DE EXTREMIDADE DE GRAMPEADOR CIRÚRGICO ATRAVÉS DE BASE FIXA. A presente invenção refere-se a um aparelho que inclui um corpo com uma primeira porção de corpo, uma segunda porção de corpo oposta à primeira porção de corpo e uma porção de conexão que acopla uma extremidade proximal da primeira porção de corpo com uma extremidade proximal da segunda porção de corpo. A porção de conexão é configurada para permitir que a primeira e a segunda porções de corpo se movam em direção a e afastem uma da outra entre uma pluralidade de orientações angulares. A primeira e a segunda porções de corpo definem um ângulo de abertura distal. Um primeiro elemento auxiliar e um segundo elemento auxiliar estão dispostos sobre as superfícies voltadas para fora da primeira e da segunda porções de corpo. A primeira e a segunda porções de corpo podem ser fixadas em cada uma das orientações angulares e podem aplicar simultaneamente o primeiro e o segundo elementos auxiliares à primeira e à segunda mandíbulas, respectivamente, de um efetuador de extremidade de grampeador cirúrgico.
Patent BR-112023015422-A2 (BR)
Title: Anticorpo anti-c1s
Inventor: KOGA HIKARU
IPC: C12N15/13
Filed: 2022-04-14
Abstract: anticorpo anti-c1s. a presente invenção refere-se a anticorpos que incluem uma região de ligação ao antígeno e uma região constante de anticorpo e que se liga a c1s de uma maneira dependente do ph. a presente invenção também provê: uma composição farmacêutica compreendendo qualquer um dos ditos anticorpos; e um método para tratamento de um indivíduo tendo uma doença ou distúrbio mediado pelo complemento, ou um método para prevenção de um indivíduo sob risco de desenvolver uma doença ou distúrbio mediado pelo complemento, o método compreendendo administrar qualquer um dos anticorpos ao indivíduo.
Patent BR-112023021148-A2 (BR)
Title: Dispositivo de triagem
Inventor: TORO ANDREA
IPC: B65G47/91
Filed: 2022-04-11
Abstract: dispositivo de triagem. dispositivo de triagem para produtos em forma de folha, como placas ou ladrilhos cerâmicos, com direção principal de transporte do produto (x), caracterizado por compreender um primeiro manipulador (2), dotado de meio de preensão (21), configurado para conectar-se a um ou mais produtos, que estão alinhados ao longo de uma direção paralela à direção principal (x), em que o primeiro manipulador (2) é móvel ao longo da direção principal (x) entre uma posição de coleta, na qual o meio de preensão (21) é capaz de coletar um ou mais produtos, e uma posição de liberação, na qual o meio de preensão (21) é capaz de liberar os produtos.
Patent CZ-2793-A3 (CZ)
Title: Refrigerator door
Inventor: GARCIA SANTAMARIA SALVADOR
IPC: A47B95/02
Filed: 1993-01-13
Abstract: The refrigerating apparatus is of the type comprising at least one thermoinsulating door, with sunken handles (4) on the left side and on the right side in order to make possible the opening in one direction of rotation or the other. The handle (4) on the hinged side is sealed by a cap or cover element (14) which prevent the access to the handle. The handles are arranged at the frame (3) of the door (1) in one of the horizontal edges of said frame, thereby defining a front wall portion of the handle. <IMAGE>
Patent CZ-22297-A3 (CZ)
Title: Collapsible shed with a flexible foldable canvas roof
Inventor: CARTER MARK C
IPC: E04H15/50
Filed: 1995-07-12
Abstract: The collapsible shelter (10) includes a truss and canopy framework that permits a flexible, collapsible canopy (10) to be moved between a raised position and a lowered position. The collapsible shelter (10) includes at least three legs (16) supporting flexible poles (82) removably mounted to the tops of the legs (16) and forming the framework of the canopy. X-shaped truss pairs (50) of link members (52, 64) are connected to each of the legs (16) on each side of the shelter (10) between adjacent legs (16).
Patent CZ-25293-A3 (CZ)
Inventor: AMIDON GORDON L
IPC: A61K9/10
Filed: 1993-02-22
Abstract: Bioaktivní přípravek, obsahující a) bioaktivní činidlo; b)
hydrofilní polymer v neúplně hydratovaném stavu; a c) rozpouštědlový
systém, který je v podstatě mísitelný s vodou;
( přičemž použitý rozpouštědlový systém udržuje bioaktivní
činidlo a hydrofilní polymer v podstatě v rozpuštěné formě,
při viskozitě směsi 350 mPa. s a hodnota viskozity směsi se
po zředění vodou zvýší nad 1000 mPa. s. Tohoto přípravku
se může používat k dodávce bioaktivních činidel, například
léčiv na místo aplikace a v řadě jiných oborů.
Patent CZ-29399-A3 (CZ)
Title: Azabicyclic carbamoyloxymutilin derivatives
Inventor: TAKLE ANDREW KENNETH
IPC: C07C317/44
Filed: 1997-07-29
Abstract: Compounds of formula (3), and pharmaceutically acceptable salts and derivatives thereof, in which R<1> is vinyl or ethyl; and R<2> is a group R<3>, R<4>CH2-, or R<5>R<6>C=CH-; wherein each of R<3> and R<4> is an azabicyclic ring system or R<5> and R<6> together with the carbon atom to which they are attached form an azabicyclic ring system, are useful in the prevention and treatment of microbial infections.
Patent CZ-32699-A3 (CZ)
Title: Oxopiperazinyl derivatives and their use in preparations stabilized against action of light
Inventor: LAZZARI DARIO DR
IPC: C07D241/18
Filed: 1999-01-29
Abstract: Compounds of the formula (I) [wherein p is zero or 1; q and r, independently of each other, are an integer from 1 to 6; and s is a number ranging from 1 to 8; X is -O- or, when p is 1, X is also a group R w , R x , R y  and R 2  are, independently of each other, C 1 -C 18 alkyl, C 5 -C 12 cycloalkyl or C 1 -C 5 hydroxyalkyl, especially methyl; R 1  is hydrogen; C 1 -C 18 alkyl; oxyl; OH; CH 2 CN; C 1 -C 18 alkoxy; C 5 -C 12 cycloalkoxy; C 3 -C 8 alkenyl; C 3 -C 8 alkynyl; C 7 -C 12 phenylalkyl; C 7 -C 15 phenylalkyl, which is substituted on the phenyl ring by 1, 2 or 3 radicals selected from C 1 -C 4 alkyl and C 1 -C 4 alkoxy; C 7 -C 15 phenylalkoxy; C 7 -C 15 phenylalkoxy, which is substituted on the phenyl ring by 1, 2 or 3 radicals selected from C 1 -C 4 alkyl and C 1 -C 4 alkoxy; or R 1  is C 1 -C 8 alkanoyl; C 3 -C 5 alkenoyl; C 1 -C 18 alkanoyloxy; glycidyl; or a group -CH 2 CH(OH)-G, in which G is hydrogen, methyl or phenyl; R 2  and R 6  are hydrogen, C 1 -C 8 alkyl, C 5 -C 12 cycloalkyl or C 1 -C 4 hydroxyalkyl; R 3 , R 4 , R 5 , R 7 , R 8  and R 9  independently of each other are hydrogen, C 1 -C 8 alkyl or C 5 -C 12 cycloalkyl; and W is as described in claim 1]; the four compounds named in claim 16; and related polymers as defined in claims 6 and 7 are claimed per se. Such compounds (other than said "related polymers") may be reacted with a functional organic polymer (as defined in claim 17) to give a modified polymer. The compounds which are claimed per se, as the said "modified polymers" are effective stabilizers for organic materials, for example thermoplastic organic polymers, coating compositions or photographic materials against light, oxygen and/or heat.
Patent CZ-45097-A3 (CZ)
Title: Lifting rod for connecting lower guide of a tractor three point superstructure
Inventor: MULLER NORBERT
IPC: A01B63/102
Filed: 1997-02-13
Abstract: A housing (8) is provided in which a rod component (11) is adjustably accommodated in a hole (21) along a longitudinal axis (17). Devices are provided for fixing the rod component to the housing at a fixed length and comprise an insert bolt (24) and an insert hole in the housing. Devices are provided for adjustment of the fixed lift bar length, which comprise a threaded connection. The rod component, at least at its end extending out of the housing, has a bore section (10) with a thread in which a threaded bar (9) is adjustably inserted with its outer thread. The rod component at its end inserting in the housing is provided with a recess (13) or a hole through which the insert bolt extends.
Patent CZ-60894-A3 (CZ)
Inventor: MARGOLIN EUGENE MICHAILOVIC
IPC: B01D17/028
Filed: 1994-03-17
Abstract: Nestabilní směs je nejdříve zavedena tangenciálně do
předseparátoru (5), uvedena do krouživého pohybu, při kterém
docházíjiž k výraznému oddělení lehké frakce, která se
zavádí do horní části separaěního prostoru (14), a těžké
frakce, která se zavádí do dolní části separaěního prostoru
(14). Pomocí dělicích stěn (6, 7,8,9,10,11) se usměrňuje v
separačním prostoru (14) proudění lehké frakce střídavě
směrem dolů a pak nahoru a proudění těžké frakce střídavě
směrem nahoru a pak dolů. V zařízení k provádění způsobu
je v nádrži (1) uspořádán předseparátor (5) kruhovitého průřezu,
s protilehlými otevřenými čely, do jehož pláště je
tangenciálně zaústěn přívod (2) nestabilní směsi, mezi
předseparátorem (5) a odvody (3,4) lehčí a těžší frakce jsou
zařazeny horní dělící stěny (6,7, 8), mezi nimiž jsou zařazeny
dolní dělící stěny (9, 10, 11). Odvodu (4) těžší frakce je
předřazen sběrný prostor (12), ve své dolní části volně propojený
se separačním prostorem (14).
Patent CZ-66093-A3 (CZ)
Title: Mixture for prolonged and controlled release of a therapeutic peptide substance, and process for preparing thereof
Inventor: HEIMGARTNER FREDERIC
IPC: A61K9/22
Filed: 1992-07-15
Abstract: A composition designed for the sustained and controlled release of medicamentous peptide substances having the formula (I):Ac-D-Nal-D-pClPhe-R3-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2wherein R3 is D-Pal or D-Trp. The composition is obtained in the form of microspheres of a biodegradable polymeric material incorporating a water-insoluble salt of the peptide of formula (I).
Patent CZ-71099-A3 (CZ)
Inventor: MARFAT ANTHONY
IPC: C07D231/56
Filed: 1997-08-25
Abstract: Deriváty indazolu obecného vzorce I, kde obecné symboly
mají specifický významajejich farmaceuticky vhodné soli,
farmaceutické kompozice najejich bázi a použití těchto
sloučenin pro inhibici fosfodiesterasy PDEtypu IV nebo
produkce faktoru nekrosy nádorů u savců. Meziprodukty pro
přípravu výše uvedených sloučenin.
Patent CZ-92397-A3 (CZ)
Title: Method and system of automatic control of combustion in a furnace
Inventor: TYMOVSKI HENRYK
IPC: F23N5/20
Filed: 1997-03-26
Abstract: In the present invention there is disclosed a method for automatic controlling combustion process in a furnace with a simultaneous measurement of free oxygen (Oi2) content and carbon monoxide (CO) content in waste gases, with defined concentration (Oi2z) of free oxygen (Oi2) determined on the base of measured and defined concentration (COiz) of carbon monoxide (CO), said method being characterized by automatic reduction of the defined concentration value (Oi2z) until equality of the carbon monoxide measured and defined concentration value (COiz) is reached. So obtained reduced defined concentration value (Oi2z) changes spontaneously by a dynamic and static concentration value ({DELTA} Oi2zd + {DELTA} Oi2zs) of free oxygen (Oi2), and this changed value is the reduced in a first defined time interval (T) by a dynamic value of concentration ({DELTA} Oi2zd) while maintain said reduced defined concentration value (Oi2z) until the end of the first time interval (T), beginning at the moment when equality of the measured and defined (COiz) concentration is reached. If, after a second time interval (T), the measured (COiz) concentration value is less than the defined one, said reduced changed defined (Oi2z) concentration value is automatically reduced unit the defined (COiz) concentration value is reached. If, after the first time interval (T), the measured (COiz) concentration value is greater that that defined, than the reduced changed defined (Oi2z)concentration value is increased by the static concentration value ({DELTA} Oi2zs) and so increased value thereof is then maintained for the second time interval (T). After lapse thereof said increased defined concentration value (Oi2z) is automatically reduced provided, the measured concentration value (COiz) does not exceed the defined one, whereby any subsequent defined time interval (T) is equal as the first time interval (T). A system for automatic control of combustion process within a furnace comprises a signal counter (3, 19) of coal conveyor belt speed, sensors (2) of measured concentration value  (COiz), and path (Di22) of a defined concentration value (Oi2z) signal is connected with the path (Di222) of the (Oi2z) defined concentration variable signal via a switching system (6), whereby said path (Di222) comprises a programming device (4) having two inputs and one output connected to the input of the switching system (6), wherein said device first input (4) is connected to the sensor (2) of the measured (COiz) concentration value while the other input thereof is connected to a defined (COiz) defined concentration value post (8).
Patent SK-16996-A3 (SK)
Title: Installing of pipeline
Inventor: DICKSON DUDLEY T
IPC: F16L55/16
Filed: 1995-06-07
Abstract: Wavy plastic tube (20) is inserted together with longitudinal flexible conducting set-up (22) with the access end (11) to the steel tube connection (10, 14), which leads from the main tube (18) directed to the access end (11) of the steel tube connection (10, 14). Longitudinal flexible conducting set-up (22) consists of the flexible conducting element (24) and of the flexible spring conduct (26). The flexible conducting element (24) is dragged over the end element (32), which consists of the outer ring-shaped part (34), fixed to the plastic tube (20), and of the inner ring-shaped part (36). The flexible spring conduct (26) is on its end equipped by sensor element (60), which after entering the space of the main tube (18) sends involved signal. After the right loading of the plastic tube (20) is to the inter-space (72) between outside of the plastic tube (20) and inside of the steel tube connection (10, 14) the hardening liquid sealing substance (70) is sprayed. After the proper hardening of the sealing substance (70) the longitudinal flexible conducting set-up (22) of the plastic tube (20) is removed, inner ring-shaped part (36) is separated from the outer ring-shaped part (34) of the end element (32) to enable removing the flexible spring conduct (26).
Patent SK-17399-A3 (SK)
Title: METHOD FOR LIQUID MIXTURES CONTINUAL HOMOGENIZATION AND Aì (54) CONTINUAL HOMOGENIZER OF LIQUID MIXTURES
Inventor: MOLNAR STEFAN
IPC: B01F23/40
Filed: 1999-02-09
Abstract: After the preliminary distribution of the liquid mixtures by the disordered fill the first hydrodynamic mixing by intensive t angential spray of the partly homogenised liquid mixture follows. The homogenisation by an intensive turbulent flow of disordered fill follows, whilst before the finishing or partial distribution of the liquid homogenised or partly homogenised mixture by disor dered fill, the first or n-th hydrodynamic mixing by the intensiv e tangential suction of the partly homogenised liquid mixture fol lows. The device according to the method, consists of at least tw o distributing disordered fills (1) and of at least two hydrodyna mic mixing chambers (2), between which there is placed homogenisa tion disordered fill (3), whilst always two hydrodynamic homogeni sation disordered fills (1, 3) are tangentially interconnected by the piping (4). Distributing and homogenisation disordered fills (1, 3) consist of grids and on them dispersed smashing elements (7), for example ringlets.
Patent SK-32993-A3 (SK)
Title: Blocking system suitable especially for rail vehicles
Inventor: BALAZ ZOLTAN
IPC: B61H13/00
Filed: 1993-04-09
Abstract: Blocking system contains at least one pair of components created with controller (3) and switching mechanism (4) and one component from it is component of emergency brake system of vehicle and is controlled by second component from pair in critic place by reaching the critical value of change of position of longitudinal axis (8) of undercarriage (1) of vehicle or longitudinal axis (7) of lower part of frame (6) of body of vehicle. Whichever from couple of components (3,4) has movement bonded with movement of lower part of frame (6) of body of vehicle and the second component from this pair (3,4) has movement bonded with movement of undercarriage of vehicle.
Patent SK-57994-A3 (SK)
Title: Interproducts on base of tetrazolylphenylboronic acid
Inventor: LO YOUNG SEK
IPC: C07D257/00
Filed: 1992-11-18
Abstract: Novel tetrazolylphenylboronic acids, methods for their preparation and methods for preparing biphenyltetrazole compounds which are angiotensin II receptor antagonists or which are useful intermediates to prepare angiotensin II receptor antagonists. <??>An illustrative biphenyl tetrazole compound is 2-n-butyl-4-chloro-1-Ä2'-(tetrazol-5-yl)-1,1'-biphenyl-4-yl)methylÜ-1H-imidazole-5-methanol, potassium salt.
Patent SK-65598-A3 (SK)
Title: Antiglucocorticoid drug
Inventor: BURLAKOV SERGEI DMITRIEVICH
IPC: A61P5/38
Filed: 1996-02-01
Abstract: The invention is related to medicine and veterinary fields, in particular to nonsteroidal antiglucocorticoids. An aim of the invention is the establishment of a new class of drugs with low toxicity and high activity in regulation of sensitivity of mammalian cells to the glucocorticoid hormones. There is a naval application of an insect pheromone with long-chain aliphatic nonsteroidal structure or its synthetic analog or derivative that is unsaturated aliphatic alcohol, aldehyde or ester, for specific inhibition of glucocorticoid hormone influence on mammalian cells. The aliphatic carbon chain length of these pheromones varies from 10 to 21 carbon atoms. There is also a possibility of combining application of two or more pheromones and/or their synthetic analogs and derivatives for enhancement of therapeutic activity, selection being made on the basis of different hydrophobic properties proportional to the aliphatic carbon chain length. Difference in lengths of these chains must be no loss than five carbon atoms. Example of preparation of the pharmaceutical forms and results of comparative experiments that show their high activity are disclosed.
Patent SK-78398-A3 (SK)
Title: Tyrosin-derivate as alpha-v-integrin inhibitors, method for the preparation thereof and pharmaceutical compositon containing same
Inventor: DIEFENBACH BEATE
IPC: C07C271/28
Filed: 1996-12-16
Abstract: Disclosed are compounds of formula (I) in which X represents alkylene with 1-6 C atoms or 1,4-piperidyl; Y is absent or represents O, CONH or -CC-; R<1> represents H, CN, N3, NH2, H2N-C(=NH) or H2N-(C=NH)-NH (the primary amino groups can also be provided with conventional amino protective groups); R<2>, R<3> each independently of one another represent H, A, A-SO2-, Ar-SO2, campher-10-SO2-, COOA or a conventional amino protective group; A, R<4> each independently of one another represent H or alkyl with 1-10 C atoms; and Ar represents phenyl or benzyl which is unsubstituted or single-substituted with CH3. Also disclosed are the physiologically tolerable salts of these compounds. The compounds and salts thereof can be used as  alpha v-integrin inhibitors, in particular for treating tumours, osteoporoses, osteolytic disorders and for suppressing angiogenesis.
Patent SK-81894-A3 (SK)
Title: Adenosine derivatives, preparation method and pharmaceutical compositions containing them
Inventor: BRU-MAGNIEZ NICOLE
IPC: C07H19/16
Filed: 1992-12-29
Abstract: Disclosed are adenosine derivatives of general formula (I), wherein R1 is H, halogen, lower alkyl, lower O-alkyl, lower S-alkyl or phenyl group, while this substituent can be connected to 2-, 4-, 5-, 6- or 7-position of indole part; n is an integral number from 0 to 4; R2 has different meaning specified in description; R3 and R4 are same or different and represent H or lower alkyl; and R5 is -NHR11, wherein R11 is lower alkyl, C3-C7cycloalkyl, lower alkyl containing alcohol or ether function group or also is -(CH2)n-NR9R10, wherein R9 and R10 independently are lower alkyls or together with nitrogen atom, to which they are bonded, they make heterocyclic group. These compound has therapeutic effect, particularly analgesic and antihypertensive. Disclosed is also preparation method for the said compounds and pharmaceutical composition containing these compounds.