baber/WOPTO huggingface dataset:
Patent CA-2680736-A1 (CA)
Inventor: GRUBER ANDRAS
IPC: A61P7/04
Filed: 2007-03-15
Abstract: The present invention provides methods for inhibiting the anticoagulation effect of a thrombin inhibitor in a patient in need thereof comprising administration of a therapeutically effective amount of a variant prothrombin or thrombin that is capable of binding the thrombin inhibitor and that has reduced procoagulant activity. Variant prothrombins or thrombins of use in the methods of the present invention include thrombin mutants W215A, W215A/E217A, or variants thereof in which the amino acids at positions 215 and/or 217 are alanine. Methods are also provided in which the thrombin mutants are administered with an additional active agent, particularly hemostatic agents such as activated factor VII or activated prothrombin complex concentrate. In one embodiment of the invention, the methods are useful in the treatment of patients in which a direct thrombin inhibitor has been administered, particularly argatroban. The present invention further provides a method for quantifying the concentration of an anticoagulant in the plasma or whole blood of a patient using a variant prothrombin or thrombin titration assay.
Patent CA-2682387-A1 (CA)
Inventor: WANG LEE
IPC: G06Q40/00
Filed: 2007-04-02
Abstract: A purchase-transaction-settled online consumer referral and reward system and method using real-time specific merchant sales information is provided. The system offers merchants a one-stop place for freely publishing of their real-time and specific sales offers and offers a risk-free service to merchants to use, who will be charged only after a referred purchase occurs and a revenue income is made. The system also allows merchants to determine how much they pay to the service provider for each referred purchase transaction, based on their profit margin and market competitiveness and the system serves all merchants, online or offline, big or small, and regardless of buy, sell, and payment settlement technologies in use. The system also offers consumers a one-stop place for finding matching sales offers specifically meeting their needs, refers consumers to merchants to buy at existing merchant establishments and rewards consumers with each purchase transaction led from the service provider.
Patent CA-2686446-A1 (CA)
Title: Auto-alignment and auto-focus system and method
Inventor: SOMANI SEEMA
IPC: A61B3/00
Filed: 2008-04-25
Abstract: A patient positioning system for use with a patient comprises an optical image sensor (18). The optical image sensor measures an optical image of a tissue structure of an eye of the patient. An image sensor support supports (14) the image sensor. A patient support (12) supports the patient. A linkage (16) is coupled to the image sensor support with the patient support. A processor (20) is coupled to the optical image sensor to determine a gradient of an illumination level of the optical tissue structure image. The processor is coupled to the linkage and configured to articulate the linkage so as to adjust a separation distance from the tissue structure to the image sensor in response to the gradient of the optical tissue structure image.
Patent CA-2688134-A1 (CA)
Inventor: GOGICHEV VADIM
IPC: H01F29/14
Filed: 2008-05-15
Abstract: The invention relates to a method for influencing the magnetic coupling between two bodies (10, 12) at a distance from each other, characterized in that a controllable field displacement device (13) having a field displacement area is placed between the two bodies (10, 12) and that the magnetic field (11) present between the two bodies (10, 12) is displaced out of the field displacement area of the field displacement device (13) in a prescribed manner by corresponding actuation of the field displacement device (13).
Patent CA-2689024-A1 (CA)
Inventor: SARASA BARRIO J MANUEL
IPC: C07K16/18
Filed: 2007-12-05
Abstract: The invention relates to immunoassays which allow the detection of polypeptides in samples with a higher sensitivity than assays of the state of the art. The invention also relates to kits which provide the components needed for carrying out said immunoassays.
Patent CA-2690005-A1 (CA)
Title: Method and computer program product for creating real time online transportation/shipping negotiation & contract generation for freight
Inventor: SPAIN GERALD R
IPC: G06Q30/08
Filed: 2010-01-07
Abstract: A method and computer program product to negotiate transportation shipments online for carriers, shippers and brokers without the need for telephones or facsimile machines, while generating digitally signed rate confirmation contracts. Our method comprises of letting shippers, carriers and brokers to post transportation and shipments online and negotiate through bidding, re-bids, post comments or accept the terms agreed upon in real time, while generating a digital signed rate confirmation contract. In any respect, the present invention reduces the time and costs associated with negotiating the transportation of freight.
Patent CA-2690166-A1 (CA)
Inventor: SCHULTE DAVID L JR
IPC: B07B1/46
Filed: 2010-01-13
Abstract: A screen assembly for a vibratory separator, the screen assembly vertically-mountable and further including a support, at least two screening faces on the support, said at least two screening faces each including screening material through which fluid is flowable from outside the screen assembly into a space within the screen assembly and interiorly of the at least two screening faces, and the support including an exit from which fluid may exit from within the screen assembly; shakers with at least one such screen assembly; and methods of using such a screen assembly in a vibratory separator. This abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure and is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims, 37 CFR 1.72(b).
Patent CA-2691142-A1 (CA)
Inventor: HAMMAD AYMAN
IPC: G06K17/00
Filed: 2008-05-29
Abstract: A portable consumer device is disclosed. An electromagnetic shield is provided in the portable consumer device that is capable of preventing communication between the portable consumer device and an interrogation device. The shield is movable between a distal position in which communication with the interrogation device is enabled and a proximate position in which the shield prevents the transmitting antenna from communicating with the interrogation device.
Patent CA-2692022-A1 (CA)
Inventor: COUTURE PIERRE
IPC: H02J13/00
Filed: 2008-06-20
Abstract: An appliance and a method are intended to monitor a phase line of a section of an electrical energy grid line. The appliance comprises a device for monitoring a parameter of a phase line. The parameter is representative of routine operating conditions of the phase line and has a known propagation speed. The appliance also comprises a device for generating an event detection signal each time the parameter has a value that exceeds a threshold, and for storing a reception time when the detection signal is generated. The appliance also has a device for sending a signal representative of a geographic location of the end of the section and a device for performing a geographic location of the event once two consecutive detection signals are generated from the signal representative of the geographic location, and reception times associated with the two detection signals.
Patent CA-2692138-A1 (CA)
Inventor: BARRETT COLBY
IPC: E02D5/80
Filed: 2010-02-04
Abstract: A subsurface support is provided comprising a soil nail having an outer member and an inner member placed within the outer member. The soil nail includes features that maintain a uniform spaced relationship between the inner and outer members. The soil nail may be installed by drilling or launching through a launching device. The spaced relationship between the inner and outer members may be achieved by crimping the outer member, or by use of an insert installed between the inner and outer members. In other embodiments, the support is made of composite construction materials, and having a self-drilling capability. The soil nail has two primary members, namely, an outer threaded member, and an inner threaded member that is placed through the outer member The outer member is made from fiberglass, and a metallic drill bit is secured to a distal end of the soil nail. The inner member is preferably steel. The dual piece construction provides superior tensile and compressive strength, particularly for applications in which a coupler is used to join outer members to extend a length of the soil nail. A method is also provided to improve pull-out capacity by galvanizing the inner and outer members
Patent CA-2692821-A1 (CA)
Title: Method and system for treating feedwater
Inventor: BAILIE ROBERT E
IPC: C02F5/10
Filed: 2008-07-16
Abstract: A system for treating feedwater includes a fluidized bed heat exchanger unit connected to receive feedwater and a flash concentrator column connected to receive feedwater discharged from the fluidized bed heat exchanger unit. A spray dryer is provided to receive a solids/liquid slurry discharged from the flash concentrator column. Feedwater can be treated by converting dissolved solids in the feedwater to suspended solids, vaporizing a portion of the feedwater to produce a solids/liquid slurry, and separating solids from the solids/liquid slurry.
Patent CA-2693951-A1 (CA)
Inventor: ROSS RICHARD
IPC: C07K14/61
Filed: 2008-07-16
Abstract: We disclose growth hormone fusion proteins that have increased in vivo stability and activity; nucleic acid molecules encoding said proteins and methods of treatment of growth hormone deficiency that use said proteins.
Patent CA-2694709-A1 (CA)
Inventor: SEITZ NORBERT
IPC: B60C19/00
Filed: 2008-09-18
Abstract: A method of processing a vehicle tyre and a thixotropic balancing substance (251, 261), comprising providing a first amount of the balancing substance (251, 261) to a first circumferential balancing area (250, 260) on an inner side of the vehicle tyre comprising distributing the first amount of the balancing substance on the first balancing area substantially uniformly; and a corresponding apparatus and system. In one embodiment a varnish layer comprising manoparticles (252, 262) is provided on the first circumferential balancing area (250, 260) to increase the movability of the thixotropic balancing substance (251, 261) on the balancing area (250, 260).
Patent CA-2695088-A1 (CA)
Inventor: DEHMLOW HENRIETTA
IPC: C07D409/12
Filed: 2008-08-04
Abstract: The invention is concerned with novel piperazine amide derivatives of formula (I) wherein R1 to R11, W, X and Y are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds bind to LXR alpha and LXR beta and can be used as medicaments.
Patent CA-2696108-A1 (CA)
Inventor: TOMBERLI MARIO
IPC: B63J99/00
Filed: 2010-03-15
Abstract: An outboard motor carrier device is arranged for carrying an outboard motor including a transom bracket arranged to be clamped onto a transom of a boat. The carrier device includes an upright frame including opposing front and rear sides and a pair of shoulder straps on the front side which are arranged to be secured over respective shoulders of a user. A transom bracket mount in the form of an upright panel is supported on the rear of the frame onto which the transom bracket of the outboard motor is clamped. Typically the transom bracket mount is positioned on the upright frame such that the transom bracket mount is arranged to wholly support the outboard motor thereon without any additional securement of the outboard motor to the upright frame of the carrier device being required.
Patent CA-2696581-A1 (CA)
Title: Apparatus and methods to control fluid flow in a downhole tool
Inventor: MILKOVISCH MARK
IPC: E21B49/10
Filed: 2008-08-12
Abstract: The present invention relates to a pumping system (600) for controlling fluid flow in a downhole tool (200). The pumping system icludes a hydraulically actuatable device including at least one cavity for receiving pressurized hydraulic fluid (616) and a reservoir (608) for storing the hydraulic fluid. A first (602a) and second (602b) hydraulic pump include an inlet (612a, 612b) fluidly coupled to the reservoir (608) and an outlet (614a, 614b) fluidly coupled (616) to the at least one cavity. At least one motor (604) is operatively coupled to at least one of the first (602a) and second (602b) hydraulic pumps. In addition, the system includes means (622a, 622b) for selectively flowing hydraulic fluid from the outlet of at least one of the first and second pumps to the at least one cavity.
Patent CA-2697827-A1 (CA)
Inventor: HARTMANN ROLF
IPC: A61K31/39
Filed: 2008-08-22
Abstract: The invention relates to 17beta-hydroxysteroid dehydrogenase type 1 (17betaHSD1) inhibitors, the preparation thereof and the use thereof for the treatment and prophylaxis of hormone-related, especially estrogen-related or androgen-related, diseases.
Patent CA-2699053-A1 (CA)
Title: Sleeve for flexographic printing
Inventor: GRASSLER REINHARD
IPC: B41M1/04
Filed: 2008-09-12
Abstract: Use of a sleeve for flexographic printing, comprising: a base sleeve; an intermediate layer enlarging the printing length, provided on the base sleeve and having a thickness of from 2 to 20 mm; a laser-engravable layer of a radiation-cured polymer; for enlarging the repeat.
Patent CA-2699932-A1 (CA)
Inventor: LECLERC DELPHINE
IPC: C08L23/02
Filed: 2007-09-19
Abstract: A thermally expandable material comprising: a) from 3 to 40 % by weight of a first thermoplastic elastomer having a first glass transition temperature, b) from 3 to 40 % by weight of a second thermoplastic elastomer having a second glass transition temperature, wherein the first and the second glass transition temperature differ by at least 10 °C c) from 5 to 50 % by weight of at least one thermoplastic polymer selected from the group consisting of polymers and copolymers with at least one polymerizable C  = C  double bond, d) from 0 to 30% by weight of at least one tackifying resin, e) at least one latent chemical blowing agent in an amount effective to cause the expandable material to expand at least 50 % in volume when heated at a temperature of 150 °C  for at least 20 minutes, wherein the sum of components a) to e) is less than 100 % by weight, and the remainder to 100 % by weight is made up of further components or adjuvants.  Preferably, the material comprises: a first thermoplastic elastomer which has a glass transition temperature in the range from -25 to 0.0 °C, a second thermoplastic elastomer which has a glass transition temperature in the range from 0.1 to 30 °C, at least one thermoplastic polymer c) selected from the group consisting of ethylene/vinyl acetate copolymers and ethylene/methyl acrylate copolymers, at least one latent chemical blowing agent, at least one curing agent based on sulfur and/or sulfur compounds. The material can be used for various sound-dampening applications like dissipative vibratory wave barriers, sound dampening of automotive closure panel assemblies, cavity filler inserts, and constrained layer damping structures.
Patent CA-2702740-A1 (CA)
Inventor: SHEPARD MICHAEL H
IPC: A61K38/17
Filed: 2008-10-15
Abstract: The invention provides for compositions comprising engineered Her3 multimers with improved binding affinity.  Such multimers include, but are not limited to, Herl/Her 3 heterodimers in which the Her3 ligand binding domain has been optimized to increase binding to Her3. The composition also can include mixtures of Her 1 homodimers, Her 3 homodimers, and Her 1/Her 3 heterodimers.
Patent CA-2707152-A1 (CA)
Inventor: AN GANG
IPC: C12Q1/6886
Filed: 1999-01-19
Abstract: Disclosed are diagnostic techniques for the detection of human prostate disease. The invention relates particularly to probes and methods for evaluating the presence of RNA species that are differentially expressed in metastatic prostate cancer compared to normal human prostate, benign prostatic hyperplasia, and non-metastatic prostate cancer. The invention also relates to probes and methods for evaluating the presence of RNA species that are differentially expressed in the peripheral blood of individuals with the disease state compared to normal healthy individuals. Described are methods of therapeutic use for genes identified as differentially expressed in metastatic prostate cancer, and means for screening pharmaceuticals effective in treatment of prostate cancer.
Patent CA-2707355-A1 (CA)
Inventor: MOY YEI F
IPC: A61F5/30
Filed: 2008-08-01
Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second con-tainer has a port docking assembly for engaging the first container. The first con-tainer is rotatable and axially slidable within the port docking assembly.  The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second con-tainers is provided when the first and second containers are in the second, activated position.
Patent CA-2709323-A1 (CA)
Title: Demonstrateur de propriete hydrophobe
Inventor: CALANDRINI FABIEN
IPC: G01N13/00
Filed: 2010-07-21
Abstract: Un démonstrateur de propriété hydrophobe (100) comprend un support d'échantillon inclinable (10) et un réservoir supérieur (20) pour produire des gouttes (G A, G B) qui tombent sur un échantillon (A, B) placé sur le support. Les gouttes sont produites régulièrement avec une taille constante en sélectionnant un profil et un diamètre d'un trou (23, 24) au fond du réservoir, et en maintenant constant un niveau d'eau (N) dans ledit réservoir. Un tel démonstrateur est particulièrement adapté pour montrer l'efficacité d'un comportement hydrophobe de verres de lunettes.
Patent CA-2711210-A1 (CA)
Inventor: GAUGLER BERND
IPC: C25B13/02
Filed: 2010-07-26
Abstract: The present invention relates to a bipolar plate as well as to a method for its production. The bipolar plate preferably comprises at least two layers (2, 3) with at least two layers (2,3) comprising each at least a first and a second indentation/protrusion, where the first indentation/protrusion (2a) of the first layer (2) and the first indentation/protrusion (3a) of the second layer (3) in a completely positioned state of the layers (2, 3) engage with each other and contact each other in the plane E1 with positive fit. The second indentation/protrusion (2b) of the first layer (2) and the second indentation/protrusion (3b) of the second layer (3) engage with each other in a completely positioned state of the layers (2,3) and contact each other in the plane E2 only in sections in at least two sections (30b, 31b). The contact portions (30b, 31b) are arranged on both sides of a virtual straight line(5b), which extends in the main direction of the indentation/protrusion (3b) in the second layer (3). No positive fit between the interlocking second indentations/protrusions (2b, 3b) results in the area of the second contact area (23). The invention allows a fast, cost efficient and tailored production of bipolar plates.
Patent CA-2711253-A1 (CA)
Inventor: ALLEN CHARLES ROBERT
IPC: A61B8/00
Filed: 2008-12-16
Abstract: A transformer board is disclosed. In some embodiments, the transformer board includes a base, a circuit board, a transformer having a first and second winding, a first and a second connector, a ribbon cable and a nonconductive fill material. The base has a recess within which the circuit board is positioned. The transformer is mechanically coupled to the circuit board.  The first connector is configured to electrically couple to transducers within a pressure boundary of an ultrasonic flow meter and is electrically coupled to the second winding of the transformer.  The ribbon cable is electrically coupled between the first winding of the transformer and the second connector. The nonconductive fill material is contained by the recess and encases the circuit board, the transformer, the coupling of the first connector to the second winding of the transformer, and the coupling of the ribbon cable to the first winding of the transformer.
Patent CA-2711669-A1 (CA)
Inventor: GARZA JOSE ARTURO
IPC: H02G3/04
Filed: 2009-01-07
Abstract: A vertical cable manager includes a base, an interconnected double-spine assembly topped by a top frame, and a pair of doors. The double-spine assembly is supported by the base. Each door is removably coupled at each lower corner to the base and at each upper corner to the top frame, thus permitting each door to be opened or hinged along either of its lateral sides or removed entirely. The double-spine assembly may support selectively repositionable mounting members, which may in turn support a large cable spool, a selectively repositionable shelf-mounted handle spool assembly, and various other cable management accessories.
Patent CA-2715816-A1 (CA)
Inventor: ABRIGNANI SERGIO
IPC: A61K35/26
Filed: 2009-03-26
Abstract: The present invention relates to ex vivo hematopoietic cells characterized by the expression of the protein KRTCAP3 on the surface of said cells, to methods for isolating said cells and to ligands for KRTCAP3.
Patent CA-2718557-A1 (CA)
Inventor: DUPERRE MAURICE
IPC: B60C27/08
Filed: 2009-01-23
Abstract: The tire chain is adapted for snugly wrapping around an appropriately dimensioned tire and rotating therewith during use. The tire chain has a chain mesh having a plurality of links, and a plurality of wear inserts interspaced on the mesh and mounted to corresponding selected ones of the links. Each one of the wear inserts has a radially-inner component removably secured to a radially-outer component, independently from the integrity of the mesh, with a spacing therebetween within which the corresponding selected link is received and trapped. The radially-outer components having corresponding outward-facing wear portions submitted to wear during use. The wear inserts can be removed and replaced once worn by separating the radially-inner component from the radially-outer component.
Patent CA-2718981-A1 (CA)
Inventor: FAITH PATRICK L
IPC: G06Q20/00
Filed: 2009-03-19
Abstract: There is provided a card or token for use in financial transactions. The financial transaction token or card has an onboard energy storage device that enables onboard electronics to operate when the card is not in the proximity of a merchant Point-Of-Service (POS) terminal. In one implementation, the onboard energy storage device includes a capacitor such as a thin--film capacitor that stores sufficient energy to power onboard electronics without the need for an onboard battery. The card may be incorporated within various conventional apparatus such as a see-through and/or protective substrate, an item of clothing, an item of jewelry, a cell phone, a Personal Digital Assistant (PDA), a credit card, an identification card, a money holder, a wallet, a per-sonal organizer, a keychain payment tag, and like personality.