baber/WOPTO huggingface dataset:
Patent MX-2019000661-A (MX)
Title: Novel fatty acid modified urocortin-2 analogs for the treatment of diabetes and chronic kidney disease.
Inventor: LILI GUO
IPC: A61K38/00
Filed: 2017-07-13
Abstract: The present invention provides a compound or a pharmaceutically acceptable salt of the Formula : X1 I V X2 S L D V P I G L L Q I L X3 E Q E K Q E K E K Q Q A K* T N A X4 I L A Q V-NH2 wherein the X1 denotes that the I residue is modified by either acetylation or methylation at the N-terminus; wherein X2 is L or T; wherein X3 is L or I; wherein X4 is Q or E; and wherein a modified K residue ("K*") at position 29 is modified through conjugation to the epsilon-amino group of the K-side chain with a group of the formula -X-5X6, wherein X5 is selected from the group consisting of one to four amino acids; one to four ([2-(2-Amino-ethoxy)-ethoxy]-acetyl) moieties; and combinations of one to four amino acids and one to four ([2-(2-Amino-ethoxy)- ethoxy]-acetyl) moieties; and X6 is a C14-C24 fatty acid. In some embodiments, the group of the formula -X5 -X6 is ([2-(2-Amino-ethoxy)-ethoxy]-acetyl)2-(Î³E)2-CO-(CH< sub>2)x-CO2H where x is 16 or 18.
Patent MX-2019000860-A (MX)
Title: Method for the microbial production of specific natural capsaicinoids.
Inventor: HUI CHEN
IPC: C12N9/00
Filed: 2017-07-19
Abstract: The present invention relates to the production of capsaicinoid compounds including Capsaicin and Nonivamide via microbial fermentation.
Patent MX-2019002716-A (MX)
Title: Geographic area monitoring systems and methods that balance power usage between multiple unmanned vehicles.
Inventor: Donald R High
IPC: G08G5/00
Filed: 2017-09-08
Abstract: In some embodiments, unmanned aerial task systems are provided that comprise multiple unmanned aerial vehicles (UAV) each comprising: a UAV control circuit; a motor; and a propulsion system coupled with the motor and configured to enable the respective UAVs to move themselves; and wherein a first UAV control circuit of a first UAV of the multiple UAVs is configured to access power level data corresponding to each of the multiple UAVs, and select a second UAV of the multiple UAVs based at least in part on a power level of the second UAV relative to a threshold power level corresponding to a first task to be performed and a predicted power usage by the second UAV while utilizing a first tool system temporarily cooperated with the second UAV in performing the first task.
Patent MX-2019004569-A (MX)
Title: Method for producing 3-alkylsulfanyl-2-chloro-n-(1-alkyl-1h-tetra zol-5-yl)-4-trifluoromethyl-benzamides.
Inventor: MARK JAMES FORD
IPC: C07C323/09
Filed: 2017-10-16
Abstract: The invention relates to a method for producing 3-alkylsulfanyl-2-chloro-N-(1-alkyl-1H-tetrazol-5-yl)-4-trifluo romethyl-benzamides of formula (I). In said formula, the substituents R1 and R2 represent residues such as alkyl and substituted phenyl.
Patent MX-2019004763-A (MX)
Title: Combination treatments comprising imidazopyrazinones for the treatment of psychiatric and/or cognitive disorders.
Inventor: JAN KEHLER
IPC: A61P25/18
Filed: 2017-10-26
Abstract: The present invention provides combination treatments comprising administration of compounds that are PDE1 enzyme inhibitors and other compounds useful in the treatment of psychiatric and/or cognitive disorders such as for example Attention Deficit Hyperactivity Disorder (ADHD), depression, anxiety, narcolepsy, schizophrenia, cognitive impairment or cognitive impairment associated with schizophrenia (CIAS). Separate aspects of the invention are directed to the combined use of said compounds for the treatment of psychiatric and/or cognitive disorders. The present invention also provides pharmaceutical compositions comprising said PDE1 enzyme inhibitors together with other compounds useful in the treatment of psychiatric and/or cognitive disorders.
Patent MX-2019005208-A (MX)
Title: Replication method for obtaining mirrors used in optical systems up to the diffraction limit.
Inventor: Luis Carlos ÁLVAREZ NÚÑEZ
IPC: G02B7/182
Filed: 2019-05-03
Abstract: The present invention relates to a replication method for obtaining mirrors used in optical systems, which consists of (a) cleaning an optical master or mold to eliminate all the fat and dust that may be adhered to its surface, (b) cutting a protective film and placing it on the face to replicate from the optical master's degree, (c) cut an internal circle on the protective film to limit the surface of interest forming a plasticized ring. Also, it includes (d) apply a thin film from a demolding agent on the face of the optical master's degree that will be replicated, (e) place a containment ring on the optical master's degree to reduce the Fiber-Print phenomenon, (f) weigh an amount ranging of up 5g to 20g of an epoxy resin. Separately, weigh a number of a catalyst agent into a falling or empty chamber to remove the highest amount of air bubbles, (g) remove the epoxy resin from progress and the catalyst agent and mix them, subsequently back to the falling chamber to suck by vacuum all bubbles that may have been formed in mixing. Further, it consists of (h) deposit a layer of at least 0.5 mm from the epoxy resin mixture and catalyst agent inside the containment ring, (i) place within the containment ring at least one layer of carbon fiber previously impregnated with the epoxy resin mixture and catalyst agent, and cure for a time of up 24hr to 48hr at room temperature. Finally, it involves (j) demolding the mirror obtained from the optical master's degree, which has a reflective surface with high optical quality.
Patent MX-2019006357-A (MX)
Title: Aluminum-free antiperspirant/deodorant compositions.
Inventor: SHARON KENNEDY
IPC: A61K8/81
Filed: 2017-12-07
Abstract: An aluminum-free antiperspirant/deodorant composition in the form of stick, cream, or flowable gel includes a carrier that includes a polyhydric alcohol or is a mixture of a polyhydric alcohol and water; a thickening agent including a C14-22 fatty acid salt; and an antiperspirant active and optionally a film-forming polymer dispersed in the carrier. The antiperspirant active is primarily a zinc-based antiperspirant active.
Patent MX-2019007470-A (MX)
Title: Polymorphs of herbicidal sulfonamides.
Inventor: PAUL NICHOLSON
IPC: A01N33/18
Filed: 2017-12-14
Abstract: Solid polymorphic forms of sulfentrazone are described. Particularly, a new polymorphic form of sulfentrazone is described herein as sulfentrazone-1, having surprising property advantages over technical sulfentrazone. Processes for the preparation of sulfentrazone-1, herbicidal compositions comprising sulfentrazone-1, and methods of its use are described.
Patent MX-2019010928-A (MX)
Title: Temperature control system for remote water tanks.
Inventor: MIKE LISK
IPC: G05D23/19
Filed: 2018-03-15
Abstract: In one aspect, the present disclosure is directed to preventing or lessening ice in remote water tanks. The remote water tanks can include a body at least partially defining a chamber that receives a liquid and having aft open top portion that provides one or more animals access to the liquid. Further, a 'heat exchanger can be at least partially received within the -chamber, and cart receive a thermal transfer fluid that is circulated therethrough to maintain a temperature of the liquid is the chamber. Also, an external heat collector can be in fluid communication with the heat exchanger to transfer solar or other heat to the thermal transfer fluid as the thermal transfer fluid is circulated therethrough.
Patent MX-2019011927-A (MX)
Title: Anti-ilt4 antibodies and antigen-binding fragments.
Inventor: LUIS A ZUNIGA
IPC: C07K16/28
Filed: 2018-04-05
Abstract: The present invention provides antibodies and antigen-binding fragments thereof that bind to ILT4 (immunoglobulin-like transcript 4) and combinations thereof, e.g., with an anti-PD1 antibody. Also provided are methods of use thereof, for example, for treating or preventing cancer in a subject; and methods of making such antibodies and fragments.
Patent MX-2019013937-A (MX)
Title: Method for preparing heterocyclic derivative compound, composition containing same compound, and hydrate of same compound.
Inventor: DO KYU PYUN
IPC: A61K31/5383
Filed: 2018-05-24
Abstract: The present invention relates to: a novel method for preparing a heterocyclic derivative compound of chemical formula I below; a novel intermediate compound used in the preparation method; a composition for treatment or prevention of hyperuricacidemia, gout, nephritis, chronic renal insufficiency, nephrolith, uremia, urolithiasis, or a uric acid-related disease, the composition containing the compound of chemical formula I at a dose of more than 2 mg and equal to or less than 10 mg and being orally administered once a day; and a hydrochloride 1.5 hydrate of the novel compound of chemical formula I.
Patent MX-2020000329-A (MX)
Title: Display substrate and preparation method therefor, display panel, and display apparatus.
Inventor: LI MEI
IPC: G06F3/041
Filed: 2019-07-31
Abstract: A display substrate and a preparation method therefor, a display panel, and a display apparatus. The display substrate (100) comprises a base substrate (10) and repeating units (11), the repeating units (11) comprising a plurality of sub-pixels (12), comprising first sub-pixels (G1) and second sub-pixels (G2), the colour of the light emitted by a light-emitting element (120a) of the first pixels (G1) being the same as the colour of the light emitted by a light-emitting element (120b) of the second sub-pixels (G2), the shape of a first light-emitting voltage applying electrode (1201a) of the light-emitting element (120a) of the first sub-pixels (G1) being different to the shape of a second light-emitting voltage applying electrode (1201b) of the light-emitting element (120b) of the second sub-pixels (G2), each sub-pixel (12) comprising a light-emitting element (120) and a pixel circuit (121) driving the light-emitting element (120) to emit light, the orthogonal projection of the first light-emitting voltage applying electrode (1201a) of the light-emitting element (120a) of the first sub-pixels (G1) on the base substrate (10) at least partially overlapping the orthogonal projection of a control end of the drive circuit (122a) of the pixel circuit (121a) of the first sub-pixels (G1) on the base substrate (10), and the orthogonal projection of the first light-emitting voltage applying electrode (1201b) of the light-emitting element (120b) of the second sub-pixels (G2) on the base substrate (10) at least partially overlapping the orthogonal projection of a control end of the drive circuit (122b) of the pixel circuit (121b) of the second sub-pixels (G2) on the base substrate (10).
Patent MX-2020002527-A (MX)
Title: Iron complex compounds for therapeutic use.
Inventor: CHRISTENSEN TOBIAS S
IPC: A61K33/26
Filed: 2018-09-10
Abstract: The present invention relates to iron complex compounds for therapeutic use which are low in arsenic, chromium, lead, cadmium, mercury and/or aluminum, compositions thereof and processes for preparing said iron complex compounds.
Patent MX-2020002724-A (MX)
Title: Closure for a container.
Inventor: PRUSKO CURT
IPC: B65D50/04
Filed: 2017-09-28
Abstract: A closure (40, 240) for a fluent substance-containing system, such as a container, includes a body (54, 254) for receiving the fluent substance from the system, an actuator (60, 260) assembled with the closure body (54, 254) for selectively preventing or permitting flow of the fluent substance through the closure body (54, 254), and a shell (56, 256) that is mounted around at least a portion of the closure body (54, 254). The shell (56, 256) has a top end (156) and a blocking member (176) having an initial configuration and a separated configuration. In the initial configuration, the blocking member (176) is connected to the top end (156) to prevent the actuator (60, 260) from moving into an open, dispensing position. In the separated configuration, the blocking member (176) is at least partially separated from the top end (156) to allow the actuator (60, 260) to move into the open, dispensing position.
Patent MX-2020003063-A (MX)
Title: Drain hose and drain hose connection method.
Inventor: MATSUSHITA MASAYA
IPC: F24F13/22
Filed: 2017-09-28
Abstract: This drain hose (10) is provided with: a hose main body (11) into which a drain pipe (3) is inserted; and a circumferential rib (12) formed on the outer peripheral surface of the hose main body (11) at a distance from the front end (11a) of the hose main body (11) and extending in the circumferential direction of the hose main body (11). The drain hose (10) is provided with an axial rib (13) which is formed on the outer peripheral surface of the hose main body (11) at a position closer to the front end (11a) of the hose main body (11) than the circumferential rib (12), and which extends in the axial direction of the hose main body (11).
Patent MX-2020007251-A (MX)
Title: Method for obtaining a ferrofluid of iron oxide nanoparticles covered with dopamine.
Inventor: CANO GONZÁLEZ MARIO EDUARDO
IPC: A61K33/26
Filed: 2020-07-13
Abstract: The present invention relates to a method for obtaining a dopamine-coated iron oxide nanoparticle ferrofluid. Said method consists of adding an iron chloride solution and a heptahydrate iron sulfate solution to a container, ii) adding an ammonium hydroxide solution to obtain a ferrofluid of iron oxide nanoparticles, iii) precipitating the said nanoparticles with a magnet and separating them from the supernatant, and iv) repeating the precipitation in an aqueous medium several times. Also, it includes v) adding a mass fraction of dopamine hydrochloride, vi) subjecting the mixture obtained to a sonication process to homogenize it and subjecting it to centrifugation, and vii) measuring its pH adding an acid or basic salts to reach a neutral pH, obtaining the ferrofluid of dopamine-coated iron oxide nanoparticles with appropriate colloidal stability.
Patent MX-2020007318-A (MX)
Title: Heterocyclic compound.
Inventor: IKEDA SHUHEI
IPC: A61P21/00
Filed: 2018-09-27
Abstract: Provided is a compound which has an MAGL inhibitory effect and is expected to be useful as a prophylactic or therapeutic agent for neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, Hutchinson's disease, amyotrophic lateral sclerosis, traumatic brain injury, glaucoma, multiple sclerosis, etc.), anxiety disorders, pains (e.g., inflammatory pain, cancer pain, neuropathic pain, etc.), epilepsy, depression and the like. The present invention pertains to a compound represented by formula (I): [wherein each symbol is as described in the description] or a salt thereof.
Patent MX-2020007807-A (MX)
Title: Utensils for stacking.
Inventor: OAKES SHAWN ALLEN
IPC: A47G21/04
Filed: 2019-01-18
Abstract: A cutlery utensil that include a functional section and a handle. The handle can include a raised spine disposed on a first surface of the handle and having a height that varies from a first end of the handle in the direction of the functional section. At least one recessed channel can be formed in a second surface of the utensil, the second surface of the utensil being opposite the first surface of the utensil, wherein the recessed channel has a depth that varies from the first end of the handle in the direction of the functional section.
Patent MX-2020008007-A (MX)
Title: Wipe dispensing.
Inventor: SHANAHAN JOHN PATRICK
IPC: A47K10/34
Filed: 2019-01-30
Abstract: Devices, systems, and methods of the present disclosure are directed to dispensing wipes that are treated as the wipes move through a housing of a dispenser. Such in situ treatment of the wipes may facilitate, for example, achieving control over one or more of the concentration, composition, or distribution of one or more chemicals carried by the wipes. Further, or instead, the one or more chemicals may be formed within the housing (e.g., just prior to treating the wipes), which may be useful for treating the wipes with chemicals that have limited stability and/or for reducing chemical handling requirements along a supply chain.
Patent MX-2020008557-A (MX)
Title: Agricultural formulations, uses thereof and processes for preparation thereof.
Inventor: ZHOU KE
IPC: A01N25/24
Filed: 2019-02-15
Abstract: The present invention is generally directed to an agricultural formulation comprising, ethaboxam, metalaxyl and a compound selected from the group consisting of 3-(difluoromethyl)-1-methyl-N-[(3R)-1,1,3-trimethyl-2,3-dihydro inden-4-yl]pyrazole-4-carboxamide and mandestrobin, a process for preparing the agricultural formulation and methods of use thereof.
Patent MX-2020011785-A (MX)
Title: Sulphate-free cleansing composition.
Inventor: RILEY ROBERT GEORGE
IPC: A61Q5/00
Filed: 2019-05-07
Abstract: 1. A sulphate free cleansing composition for hair and scalp comprising, in an aqueous continuous phase: a total amount of anionic surfactant, amphoteric surfactant and zwitterionic surfactant consisting of: (i) from 3 wt % to 13 wt %, by weight of the total composition at 100 % activity, of an alpha olefin sulfonate anionic surfactant of general formula (I): R<sup>1</sup>-CH=CH-CH<sub>2</sub>-SO<sub>3</sub> <sup>-</sup>M<sup>+</sup> (I) in which R<sup>1</sup> is selected from linear or branched alkyl groups having from 11 to 13 carbon atoms and mixtures thereof; and M is a solubilizing cation; (ii) from 1 to 6%, by weight of an amphoteric or zwitterionic surfactant, selected from an alkyl betaine of general formula (II) R<sup>2</sup>-N<sup>+</sup>(CH<sub>3</sub>)<sub>2</sub>-CH<sub> 2</sub>-COO<sup>- </sup>M<sup>+</sup> (II) wherein R<sup>2</sup> = C12 (Lauryl) or Coco derived; an alkyl hydroxy sultaine of general formula (III), R<sup>3</sup>-N+(CH<sub>3</sub>)<sub>2</sub>-CH<sub>2</sub>-CH( OH)-CH<sub>2</sub>-SO<sub>3</sub> <sup>- </sup>M<sup>+</sup> (III) wherein R<sup>3</sup> = C12 (Lauryl) or Coco derived; an alkyl aminopropyl hydroxy sultaine of general formula (IV), R<sup>4</sup>-CO-NH-(CH<sub>2</sub>)<sub>3</sub>-N<sup>+</sup>( CH<sub>3</sub>)<sub>2</sub>-CH<sub>2</sub>-CH(OH)-CH<sub>2</sub> -SO<sub>3</sub> <sup>-</sup>M<sup>+</sup> (IV) wherein R<sup>4</sup> = C12 (Lauryl) or Coco derived; an alkyl amphoacetate of general formula (V), R<sup>5</sup>-CO-NH-(CH<sub>2</sub>)<sub>2</sub>-N(CH<sub>2</su b>-CH<sub>2</sub>-OH)(CH<sub>2</sub>-COO<sup>- </sup>M<sup>+</sup>) (V) wherein R<sup>5</sup> = C12 (Lauryl) or Coco derived; and mixtures thereof; (iii) from 0.05 to 0.9 wt% of a cationic conditioning polymer; (iv) from 0.05 to 10 wt % of a silicone emulsion; (v) a cationic deposition polymer; (vi) an inorganic electrolyte; and (vii) water in which the weight ratio of (i) to (ii) ranges from 1:1 to 6:1 and the pH of the composition is from 3 to 6.5.
Patent MX-2021003244-A (MX)
Title: Transcranial magnetic stimulation systems and methods.
Inventor: LOWIN LEEAM
IPC: A61N2/12
Filed: 2018-12-18
Abstract: A transcranial magnetic stimulation device in accordance with embodiments of the present invention comprises a head mount for disposition on a head of a patient and configured with a plurality of attachment points, a plurality of magnetic assembly devices connected to the plurality of attachment points, a given magnetic assembly device equipped with an actuator device to actuate a magnet, is addressable, and configured to receive a control signal addressed to the given magnetic assembly device, and a processor having a memory and configured by program code. The processor is configured to: select one or more treatment protocol units, generate a control signal using at least information contained in the selected treatment protocol units, energize at least one magnetic assembly device over a period of time to cause the magnet to actuate according to the control signal, and monitor the patient response to energizing to addressable actuator.
Patent MX-2021003918-A (MX)
Title: Pooling device for single or multiple medical containers.
Inventor: JONES SETH DALE
IPC: A61M5/162
Filed: 2019-09-24
Abstract: A medicinal fluid pooling device may be used to pool multiple containers of medicinal fluid to facilitate administration of the medicinal fluid to a patient. A medicinal pooling device may include spikes covered by spike sheaths which are pierced when a container of medicinal fluid is inserted into the medicinal pooling device. The medicinal pooling device may also include a cover configured to cover the spikes. The medicinal pooling device may also include a fluidic interface which may be used to fluidly connect the medicinal pooling device to an infusion pump or syringe.
Patent MX-2021005353-A (MX)
Title: Compositions, methods and systems for protein corona analysis and uses thereof.
Inventor: FAROKHZAD OMID
IPC: G01N33/68
Filed: 2019-11-07
Abstract: Compositions, methods, and systems for analyzing the protein corona are described herein, as well as its application in the discovery of advanced diagnostic tools as well as therapeutic targets.
Patent MX-2021005390-A (MX)
Title: Novel amorphous active pharmaceutical ingredients comprising substantially amorphous mesoporous magnesium carbonate.
Inventor: FRYKSTRAND ÅNGSTRÖM SARA
IPC: C01F5/24
Filed: 2019-11-06
Abstract: The present invention is directed to a solid and substantially amorphous active pharmaceutical ingredient, to an oral pharmaceutical formulation comprising said substantially amorphous active pharmaceutical ingredient, as well as to a method for the manufacture of the same. The invention is also directed to a particulate anhydrous and substantially amorphous mesoporous magnesium carbonate(MMC), to a method for the manufacture thereof, and the use of said particulate anhydrous and substantially amorphous mesoporous magnesium carbonate (MMC)to stabilize an active pharmaceutical ingredient (API).
Patent MX-2021006408-A (MX)
Title: Radioimmunoconjugates and dna damage and repair inhibitor combination therapy.
Inventor: BURAK ERIC STEVEN
IPC: C07D237/32
Filed: 2019-12-03
Abstract: Combination therapies comprising administering radioimmunoconjugates and DNA damage response inhibitors.
Patent MX-2021007390-A (MX)
Title: Apparatus and method for detection of line to neural back-feed voltage.
Inventor: CRITTENDEN CURTIS W
IPC: H02H3/20
Filed: 2019-12-20
Abstract: An electric utility distribution system in which power is supplied by a distribution transformer through an electric utility meter including an apparatus for detecting the presence of a back-feed voltage source connected to the load. The apparatus includes a virtual neutral established in the electric utility meter at ground potential and a remote switch that is opened to interrupt electric power flow from the distribution transformer to the load. The apparatus further includes a balanced voltage divider circuit including a connection point established between a pair of series connected resistive elements. In addition, the apparatus includes a detection circuit configured to monitor a voltage signal at the connection point to detect a back-feed voltage source connected between a neutral conductor of the electric utility distribution system and one of a first or second power line at the load.
Patent MX-2021010453-A (MX)
Title: Antibody-drug conjugates including antibody against human dlk1, and use thereof.
Inventor: KIM YONG ZU
IPC: C07K16/28
Filed: 2020-03-05
Abstract: The present invention relates to: novel antibody-drug conjugates (ADC) targeting DLK1; active metabolites of the ADCs; a method for producing the ADCs; a use of the ADCs for treating and/or preventing diseases; and a use of the ADCs for producing medicaments for treating and/or preventing diseases, more specifically, hyperproliferative and/or angiogenic diseases such as cancer. More particularly, the present invention relates to an antibody-drug conjugate comprising an antibody binding to DLK1 or an antigen-binding fragment thereof, and to a pharmaceutical composition including same.