baber/WOPTO huggingface dataset:
Patent CA-2172974-C (CA)
Inventor: OKAYAMA MINENOBU
IPC: C12N15/87
Filed: 1994-09-28
Granted: 2005-07-12
Abstract: The present invention provides a poly-amino acidic oligonucleotide-carrier comprising a poly-lysine:serine random copolymer.      This carrier is bonded with oligonucleotide without causing precipitation, and smoothly releases the bonded oligonucleotide within cells. It is therefore useful as an in vivo transport carrier of an oligonucleotide drug against various genetic diseases and viral diseases such as AIDS. It also makes a great contribution to creation of various useful animals and plants by genetic engineering technique, including virus-resistant plants.
Patent CA-2173273-C (CA)
Inventor: WOOLF LAWRENCE D
IPC: H01B13/00
Filed: 1996-04-02
Granted: 2002-07-09
Abstract: A melt  processing method  for  bulk  or  thick  film fabrication of RE123 superconductor material includes the steps  of  using  Nd  in  the  RE123  to  increase  the recrystallization speed of the RE123, and using a heavy rare earth in the RE123 to establish the peritectic melting point of the RE123 somewhere below the melting point of silver. Within these requirements, the method essentially includes heating the RE123 above its peritectic melting point, and then cooling the resultant decomposed material to recrystallize the RE123.  The heavy rare earths to be used for lowering the RE123 peritectic melting temperature include Lu, Yb, Tm or Er or mixtures thereof.  The addition of RE211,  silver and the use of a  low oxygen partial pressure also contribute to a lowering of the melting point of the RE123.  When using Nd to accelerate the processing time, the RE123 can include a first component of Nd1-zRz123 and a second component of Nd1-yRy211.  For these components, R is one of the heavy rare earths,  z is between 0 and approximately 0.9, and y is between 0 and approximately 0.9.
Patent CA-2177696-C (CA)
Inventor: MATHUR RAJIV
IPC: A61K8/92
Filed: 1994-10-25
Granted: 2003-03-11
Abstract: Disclosed are oil-filled paucilamellar lipid vesicles containing at least on e non-phospholipid amphiphile as the primary lipid of the vesicle bilayers and avocado oil unsaponifiables.  The vesicles are part icularly useful for delivering dermatological, cosmetic and pharmaceutical formulations. A method of manufacture for these vesicles is a lso disclosed.
Patent CA-2178668-C (CA)
Inventor: FUERTES PATRICK
IPC: C08L5/16
Filed: 1996-06-10
Granted: 2007-03-27
Abstract: The invention relates to a novel pulverulent hydroxypropyl-.beta.-cyclodextrin composition having a centred particle size free of fine particles and an appreciably improved capacity to dissolve in aqueous medium. The composition also has good flowability and has the advantage of being compressible. The invention also relates to a process for the preparation of this pulverulent hydroxypropyl-.beta.-cyclodextrin composition.
Patent CA-2185544-C (CA)
Inventor: MCGUIRE KEVIN P
IPC: F21V7/22
Filed: 1995-03-20
Granted: 2003-06-03
Abstract: A lamp for producing a spectral distribution which is substantially identical to daylight color temperature. The lamp contains a filament which, when excited by electrical energy, emits radiant energy at least within the visible spectrum with wavelengths from about 400 to about 700 nanome-ters, a reflector body with a surface to intercept and reflect the visible spectrum radiant energy which is positioned within the reflector so that at least 50 percent of the vis-ible spectrum radiant energy is directed towards the reflector surface, and a coating on the surface of the reflector body from which the reflected radiance of each wavelength of vis-ible spectrum radiant energy directed towards the reflector surface when combined with the visible spectrum radiant energy not directed towards the reflector surface produces a total light output in substantial accordance with a specified formu-la.
Patent CA-2187844-C (CA)
Title: Device for monitoring a predetermined level of a liquid in a container
Inventor: GETMAN IGOR
IPC: G01F23/296
Filed: 1996-10-15
Granted: 2000-09-26
Abstract: For monitoring a predetermined level of a liquid in a container an ultrasonic transducer is fitted on the outer surface of the container wall at a measurement point situated at the height of the  level  to  be monitored.  The  ultrasonic  transducer  when excited  by  an  alternating  voltage  pulse  having  a  given transmission  frequency  which  equals  the  thickness  resonant frequency  of  the  container  wall,  transfers  an  ultrasonic transmission pulse to the container wall and converts ultra-sonic vibrations,  generated by reflected echo pulses,  into electrical  reception  signals  that  are  transferred  to  an evaluation circuit. In the evaluation circuit, on the one hand the presence or absence of echo signals is detected, and, on the other, the ultrasonic vibrations generated by the after-vibration of the container wall at the end of the transmission pulse are evaluated. As a result of this it can be determined with high error detection reliability whether the measurement point is covered by the liquid or not and whether the measure-ment arrangement is working satisfactorily.
Patent CA-2188341-C (CA)
Inventor: DENOEL JEAN-DENIS
IPC: F02K9/28
Filed: 1996-10-21
Granted: 2002-02-19
Abstract: The control system comprises a plurality of nozzles pointing in different directions, a plurality of gas generators, and pipework connecting the gas generators to the nozzles via gates for allowing or preventing gas being ejected therethrough.  Each gas generator is fitted with a shutter (42) disposed in an outlet passage (20) connecting the generator to the pipework, the shutter having a closed position in which it closes the outlet passage by bearing against a seat (28) formed in the passage and against which it is pressed when the generator is not ignited so as to isolate the gas generator in sealed manner from gas contained in the pipework and coming from other generators, the shutter being automatically lifted off its seat to move from the closed position to an open position under the effect of the pressure produced in the generator in response to being ignited, thereby enabling control to be performed with gas generators being ignited independently of one another.
Patent CA-2193225-C (CA)
Title: Radar
Inventor: VAN OMMEREN MARINUS JOSEPHUS S
IPC: G01S7/36
Filed: 1995-06-22
Granted: 2006-05-09
Abstract: Radar doté d'une unité de transmission (1) présentant un déphaseur de transmission destiné à produire chaque impulsion transmise en une salve avec un déphasage sélectionné, et d'une unité de réception (7) présentant un déphaseur de réception (9) destiné à annuler le déphasage sélectionné lors d'une réception. Ceci permet des transmissions radar sans entrave et trompe le brouilleur répéteur opérationnel.
Patent CA-2193273-C (CA)
Inventor: LEADFORD KEVIN F
IPC: F21V7/22
Filed: 1996-12-18
Granted: 1999-07-27
Abstract: Downlight and downlight wall wash reflectors particularly useful with compact fluorescent lamps and other large-area light sources, the reflector optics of the invention maximize the efficiency of the luminaire while providing brightness control and avoidance of high angle glare or "flash". Downlight reflectors according to the invention provide a truly  uniform illuminance distribution across the illuminated area when applied in a rectangular grid with maximum use of available light by providing an upper amplifying reflector section which reflects normally underutilized light to a lower distribution reflector section which radiates a large percentage of generated light effectively from the bottom of the light source, thus reducing the apparent size of the light source and increasing optical control.  The lower reflector section reflects light only into zones where the light is needed and avoids high angle zones, most of the light being reflected into zones from 35° to 45° from vertical or nadir, thereby widening the distribution and also producing high efficiency and aesthetically pleasing performance.  Wall wash reflectors according to the invention are provided with a specular lower zone formed by a specular finish at lower portions of the wall washing reflectors to yield high light levels on a vertical wall near the ceiling line while avoiding high angle glare or "flash" in the opposite direction.
Patent CA-2198899-C (CA)
Title: Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
Inventor: BARBAS CARLOS F
IPC: A61K51/10
Filed: 1995-09-01
Granted: 2010-02-23
Abstract: The present invention describes methods for producing antibody libraries, and particularly for increasing antibody library diversity by inducing mutagenesis within the CDR regions of immunoglobulun heavy or light chains that are displayed on the surface of filamentous phage particles comprising the library. The invention also describes oligonucleotides useful for increasing the library diiversity, and universal light chains useful in the library production methods.
Patent CA-2206506-C (CA)
Title: Refrigerator mullion
Inventor: KLAAS MURRAY
IPC: F25D23/08
Filed: 1997-05-29
Granted: 2004-01-13
Abstract: A refrigerator cabinet has an outer metallic shell into which is inserted a one-piece plastic interior liner having a fresh food compartment separated by a mullion wall from the freezer compartment. The mullion wall is part of the interior liner. A metallic reinforcing mullion strap extends between side walls of the exterior cabinet shell to reinforce the side walls and prevent buckling. The mullion strap extends through an open space between the fresh food compartment and freezer compartment on the interior liner. The mullion strap does not touch the interior liner and is surrounded by thermally insulating foam whereby heat loss through the mullion strap from the refrigerator compartment is reduced. Further, the mullion wall of the interior liner is covered by a plastic mullion cap which protects the mullion wall of theinterior liner from stresses associated with door closure and includes a decorative mullion cover in which a heater is provided to compensate for sweating associate with heat loss through the mullion cap to ambient. By using a plastic mullion cap, heat loss is significantly less than using a metal mullion bar directly exposed to ambient.
Patent CA-2206888-C (CA)
Title: Eye imaging system
Inventor: BURRISS JAMES A
IPC: A61B3/117
Filed: 1995-11-14
Granted: 2009-01-06
Abstract: An eye imaging system (10) having a hand held portable image capture unit (12) connected by a cable (16) to a housing (14). The hand held unit includes a light fiber optic for transmitting light to the eye, imaging and focusing optics, and a charged couple image device.  The connecting housing provides an electrical power source, light source and viewing monitor (26) for viewing an image of the eye.
Patent CA-2211889-C (CA)
Inventor: MATESANZ-BALLESTEROS MARIA ENC
IPC: A61K31/495
Filed: 1996-01-30
Granted: 2006-10-10
Abstract: L'invention porte sur des composés de formule (I), sur leurs formes N-oxyde, sur leurs sels acides d'addition pharmacocompatibles et leurs formes stéréochimiquement isomériques. Dans ladite formule, =a1-a2=a3-a4= est un radical bivalent de formule (a) =N-CH=CH-CH= (b), =CH-N=CH-CH= (c), =CH-CH=N=CH (d), =CH-CH=CH-N-, dans laquelle un ou deux atomes d'hydrogène peuvent être substitués par halo, hydroxy, C1-6 alkyle ou C1-6 alkyloxy; R<1> est hydrogène ou C1-6 alkyle; R<2> est hydrogène ou C1-6 alkyle; R<3> est hydrogène ou C1-6 alkyle; Alk<1> est C1-5 alcanediyle; Alk<2> est C2-15 alcanediyle; Q est un anneau hétérocyclique à 5 ou 6 éléments contenant au moins un atome d'azote ou un radical de formule -C(NR5R6)=C-R4 dans laquelle R<4> est hydrogène, cyano, aminocarbonyle ou C1-6 alkyle; R<5> est hydrogène, C1-6 alkyle, C3-6 alcényle ou C3-6 alcynyle, R<6> est hydrogène ou C1-6 alkyle; et R<5> et R<6> pris ensemble peuvent former un radical bivalent de formule -(CH2)4- ou -(CH2)5-. Sont également présentées des compositions et préparations pharmaceutiques et leur utilisation comme médicaments.
Patent CA-2211932-C (CA)
Inventor: ROUNDTREE STEPHAN
IPC: B67D1/14
Filed: 1997-07-30
Granted: 2005-06-14
Abstract: A limited action flow control fluid dispenser. The fluid dispenser includes a housing, a plunger positioned within the housing, and a nozzle. The housing has a fluid inlet, a fluid outlet and a cavity. The plunger is longitudinally positioned within the cavity, and is slidably between a first position and a second position. The first position permits fluid flow from the fluid inlet through the cavity and out from the fluid outlet. The second position prevents fluid flow.  The plunger includes fast and second ends, a substantially uniformly concave section, a velocity reducing section, a sealing section, and a constant volume section. In operation, the plunger serves to reduce foaming in carbonated beverages, such as beer, and facilitate pressurization of the fluid delivery system. In another aspect of the present invention, a velocity reducing device is provided that includes a first end mated with the fluid inlet and a second end that is mated with a fluid supply line. Turbulence is created within the velocity reducing device to reduce the fluid velocity prior to entering the fluid dispenser.
Patent CA-2212124-C (CA)
Inventor: FRIEDRICH HAGEN
IPC: E05B17/22
Filed: 1997-08-21
Granted: 2006-03-28
Abstract: A lock system has a lock cylinder pivotal about an axis between a pair of end positions and through a center starting position, a key fittable into the cylinder and actuatable to pivot the cylinder between its positions, an arcuate magnet centered on the axis and coupled to the cylinder for joint movement therewith, and a pair of angularly spaced Hall-effect sensors adjacent the magnet, trippable by the magnet to generate respective outputs, and positioned such that in the central position the magnet is closely juxtaposed with and trips both sensors, in one of the end positions the magnet is closely juxtaposed with and trips only one of the sensors and is spaced from the other of the sensors, and in the other end position the magnet is closely juxtaposed with and trips only the other sensor and is spaced from the one sensor. The sensors and magnet are so constructed and relatively positioned that on pivoting of the magnet through a predetermined angle in one direction from the center position the one sensor is tripped and on pivoting of the magnet through the predetermined angle in the other direction the other sensor is not tripped. A lock system connected to the sensors has an antitheft mode initiated by the sensors on displacement of the cylinder into the antitheft end positions and provided with a latch operable on displacement of the cylinder into the lock/unlock end position.
Patent CA-2213218-C (CA)
Title: Testing devices for manually movable components of a motor vehicle
Inventor: BRAEUNER GUENTHER T
IPC: G01L5/22
Filed: 1996-02-23
Granted: 2005-07-19
Abstract: An apparatus is provided for acquiring data relating to an amount of force required to move a manually movable member operatively associated with a motor vehicle through a predetermined range of movement. The apparatus comprises a movable assembly constructed and arranged to be able to engage the manually movable member through the predetermined range of movement of the manually movable member. A drive mechanism is constructed and arranged to drive the movable assembly so that the movable assembly applies a force to the manually movable member and moves the manually movable member through the predetermined range of movement so as to generally simulate a predetermined manual movement of the manually movable member.  Circuitry is operatively connected with the movable assembly for generating electrical signals indicative of the force applied to the manually movable member by the movable assembly during the predetermined simulated manual movement of the manually movable member through the predetermined range of movement. A data processing system is responsive to the electrical signals generated by the circuitry for generating data indicative of the force applied by the movable assembly to the manually movable member during the predetermined simulated manual movement of the manually movable member through the predetermined range of movement.
Patent CA-2218732-C (CA)
Title: Chape d'empreinte a bille
Inventor: BROBERG LEIF
IPC: A61C13/265
Filed: 1996-04-17
Granted: 2000-09-05
Abstract: La présente invention concerne une chape d'empreinte temporaire à bille (1) conçue pour être utilisée au cours de la préparation d'une prothèse complète à recouvrement dentaire pourvue de dispositifs de fixation à bille permettant de fixer ladite prothèse dentaire à des éléments fixés à demeure dans la mâchoire. Cette chape est associée à un alésage (4) destiné à coopérer avec une pièce en forme de bille située sur ledit dispositif de fixation à bille. Cet alésage possède une section transversale de forme polygonale.
Patent CA-2218971-C (CA)
Inventor: KOSCO JOHN JR
IPC: F04B39/10
Filed: 1997-10-21
Granted: 2000-10-31
Abstract: In a refrigerant compressor, a discharge valve assembly which reduces reexpansion volume. The present invention provides a discharge valve assembly for reciprocating, rotary, and scroll types of compressors, and includes a spherical valve member that engages and penetrates a discharge port provided on a compressor cylinder head, valve plate or scroll plate. The discharge port is formed in the cylinder head or scroll plate and is dimensioned such that the spherical member penetrates and substantially fills the discharge port. The reexpansion volume within the discharge port is thereby reduced. To maintain engagement of the spherical member with the discharge port, an elastically deformable arm having an aperture is positioned to hold the spherical member in the discharge port. The arm is elastically deformable to allow the spherical valve member to move out of engagement with the discharge port during the compression phase of the compressor. To prevent the spherical member from being discharged along with the compressed refrigerant, a rigid stop plate is disposed adjacent the deformable arm to engage the spherical member during the compression phase and thereby limit the movement of the spherical valve member.
Patent CA-2228044-C (CA)
Title: Dibenzimidazole radioprotectors
Inventor: WHITE JOHNATHON MICHAEL
IPC: A61K31/44
Filed: 1996-07-26
Granted: 2006-11-28
Abstract: Use of a compound of formula (I) wherein X is optionally substituted aminoalkyl, optionally substituted alkylene or an interactive group; Y and Z may be the same or different and are selected from N, O, S an d C(R') wherein R' is hydrogen, optionally substituted alkyl or optionally substituted alkenyl; (see formula I) is a double bond unless t he attached Y or Z group is O or S in which case it is a single bond; and R1 to R11 may be the same or different and are selected from hydrogen, a sterically hindering group and an electron donating group; or any two of R1 to R11, Y, Z, NH and R' may together with the carbon atoms to which they are attached form an optionally substituted ring which may contain heteroatoms, provided that at least one of R1 to R11 is an electron donating group and that when X is NCH3, Y and Z are N and R1, R2 and R4 to R11 are hydrogen then R3 is not OH or OCH2CH3; an d salts thereof, pharmaceutically acceptable derivatives thereof, pro-drugs thereof and/or tautomers thereof, as a radioprotector. Al so provided is a method of protecting a subject from radiation damage, a method of protecting biological materials from damage caused by radiation or cytotoxic agents and certain novel compounds of formula (I). Processes for the preparation of the novel compounds of formula (I) are also provided.
Patent CA-2231458-C (CA)
Inventor: MINAMI YUKIO
IPC: F16K27/00
Filed: 1998-03-06
Granted: 2005-06-07
Abstract: A device for heating a fluid control apparatus comprises a tape heater disposed on at least one of opposite lateral sides of the fluid control apparatus, and a plurality of brackets each comprising a bottom wall fastened to a panel with a screw and at least one side wall for holding the tape heater in contact with a fluid controller. The bottom wall of each of the brackets is formed with a screw hole, and each bracket is attached to the panel and adjustable in position.
Patent CA-2240217-C (CA)
Inventor: DRAHUSZ GEORGE JR
IPC: B60T15/04
Filed: 1998-06-09
Granted: 2004-04-06
Abstract: The present invention provides an improved lubrication system for use in a railway locomotive brake valve. Such railway locomotive brake valve includes a suppression cam having a plurality of detented control positions. It further includes a handle connected to the suppression cam for moving the suppression cam to such plurality of detented control positions. There is a spring loaded latch mechanism for engaging the suppression cam and providing a positive stop for such plurality of detented positions. The latch mechanism is a cylindrically shaped member with an elongated convex shaped protrusion at one end for engaging the suppression cam. Such brake valve further includes a bushing surrounding and guiding such latch mechanism. Such improved lubrication system comprises a coating of a preselected low friction material applied to and dried on at least one of the latch mechanism, the bushing and the suppression cam.
Patent CA-2240364-C (CA)
Inventor: YUMOTO HIDEAKI
IPC: F16T1/24
Filed: 1998-06-11
Granted: 2004-01-06
Abstract: A liquid forced-feed apparatus has a built-in float in a hermetic vessel provided with a working fluid inlet port, a working fluid discharge port, a forced-feed liquid inlet port, and a forced-feed liquid discharge port. A snap mechanism which is actuated to operate the working fluid inlet port and the working fluid discharge port with the upward and downward strokes of the float, to thereby force a liquid in the hermetic vessel out through the forced-feed liquid discharge port. A power transmitting shaft for transmitting the upward-and-downward movement of the float to the snap mechanism extends out of the hermetic vessel. The snap mechanism is disposed outside of the hermetic vessel.
Patent CA-2241817-C (CA)
Inventor: IGNOTZ KEITH D
IPC: A61B8/00
Filed: 1996-03-21
Granted: 2009-12-22
Abstract: Un dispositif jetable de calibrage (45) est utilisé pour calibrer un système de mesure (3) qui transmet un rayonnement (39) à un matériau ou à un tissu (40), de façon à effectuer des mesures avec un spectromètre (10). Le dispositif comprend une structure comportant une fenêtre à travers laquelle le rayonnement (39) peut être transmis, ainsi qu'une cible de calibrage amovible (270) disposée dans la fenêtre et capable de renvoyer une partie du rayonnement afin de calibrer le système de mesure. On peut enlever la cible de calibrage (270) de la fenêtre ou du pourtour d'un orifice, de façon à effectuer une mesure sur le matériau ou le tissu (40). Une fois la mesure terminée, on peut enlever du système de mesure l'ancien dispositif de calibrage et y insérer un nouveau.