baber/WOPTO huggingface dataset:
Patent DE-69510186-D1 (DE)
Inventor: LEWIS NORMAN
IPC: A61P1/08
Filed: 1995-02-28
Granted: 1999-07-15
Abstract: A process for preparing granisetron (1) or a pharmaceutically acceptable salt thereof, which process comprises deprotecting a compound of Structure (2), wherein R is a nitrogen-protecting group which does not significantly reduce the nucleophilicity of a secondary amino group, and optionally forming a pharmaceutically acceptable salt.
Patent DE-69525674-D1 (DE)
Inventor: TRIAL FRANCOIS
IPC: G06K7/00
Filed: 1995-04-24
Granted: 2002-04-11
Abstract: The system has a housing (1) with two parallel slots (11,12). A first slot (11) is for the introduction of the magnetic strip on the credit card and a second slot (12) for the cheque. The housing also has a slot (14) for insertion of an integrated circuit card. The housing contains electronic input/output circuits (20,21,22) connected to a data network and also contains three readers for the payment means, cheque, magnetic track card and integrated circuit card. The housing also contains a electronic card which includes a micro-controller and memories, the micro-controller being designed to manage the payment operations by selecting, according to the method of payment being used, the appropriate reader and data processing system. <IMAGE>
Patent DE-69526502-D1 (DE)
Inventor: BAXTER JOHN FREDERIC
IPC: A23G1/18
Filed: 1995-09-27
Granted: 2002-05-29
Abstract: Edible fat compositions containing a fat capable of polymorphic transformation are rapidly crystallised by undercooling the composition by at least about 4 DEG C and subjecting the composition to ultrasonic energy in amounts sufficient to transform crystals from unstable form to stable form. Ultrasonic energy accelerates the transformation of unstable and semi-stable polymorphic crystals to stable forms, a process which can take some months to occur, so that the transformation is completed to a sufficient extent within a matter of a few seconds. Typical products so formed contain stable beta  polymorphs, and are heat-resistant and shelf-stable for at least a year. The method is less sensitive to process deviations than conventional tempering methods. <IMAGE>
Patent DE-69532810-D1 (DE)
Inventor: BRENNER GERALD S
IPC: A61K31/663
Filed: 1995-08-21
Granted: 2004-05-06
Abstract: Disclosed is a therapy protocol for treating patients having metastatic bone disease, hypercalcemia of malignancy and/or metabolic bone disease by administering an intravenous, citrate-buffered formulation of alendronate which is isotonic with human blood.
Patent DE-69534163-D1 (DE)
Inventor: YEH MING-KUNG
IPC: A61K9/52
Filed: 1995-06-19
Granted: 2005-05-25
Abstract: PCT No. PCT/GB95/01426 Sec. 371 Date Apr. 4, 1997 Sec. 102(e) Date Apr. 4, 1997 PCT Filed Jun. 19, 1995 PCT Pub. No. WO95/35097 PCT Pub. Date Dec. 28, 1995Provided are biodegradable microparticles, which exhibit a linear release profile of active agent, and methods for making the microparticles. The microparticles include a mixture of a biodegradable polymer, a water soluble polymer, and an active agent. Preferred biodegradable polymers include lactide homopolymers or copolymers of lactide and glycolide, and preferred water soluble polymers include poly(ethylene glycol) (PEG) or PEG copolymers. The microparticles are made using an emulsion/solvent extraction method, in which the continuous phase of the secondary emulsion contains an organic solvent that is miscible with the organic solvent in the primary emulsion.
Patent DE-69601455-D1 (DE)
Inventor: NOOMEN ARIE
IPC: C09D4/00
Filed: 1996-11-18
Granted: 1999-03-11
Abstract: Described is a coating composition comprising an organic compound comprising at least two acetoacetate groups or acetamide groups or a combination of these two groups and the oxide of a metal of Group IIa of the Periodic Table. The metal preferably is calcium or magnesium. The composition may further comprise a compound comprising at least two  alpha , beta -ethylenically unsaturated groups and, optionally, a catalyst for the reaction of the acetoacetate groups and/or acetamide groups with the  alpha , beta -ethylenically unsaturated groups.
Patent DE-69604859-D1 (DE)
Inventor: PIOVESAN GIANNI
IPC: H01R13/10
Filed: 1996-05-02
Granted: 1999-12-02
Abstract: A female electrical terminal comprising a flat metal body (10), obtained from blanked and stamped plate, that is connected at one end to pairs of foldable clamping flaps (12,13) for an electrical wire and is laterally provided with two longitudinal wings (14) that are folded so as to assume a substantially semitubular shape and form, together with said body (10), an electrical contact seat (16) for the flat strip of a male terminal. The female terminal is characterized in that the body (10) is longitudinally crossed by two slots (17) that form, between them, a flexible region that is provided with a stud (19) protruding towards the electrical contact seat (16). <IMAGE>
Patent DE-69616905-D1 (DE)
Inventor: PIRO GIAMPIETRO
IPC: C22C1/10
Filed: 1996-07-23
Granted: 2001-12-20
Abstract: Nickel cermet consisting of from 35 to 70% by weight of a metal nickel phase and 65 to 30% by weight of a zirconium oxide (zirconia) phase stabilized in cubic form by 5 to 20 moles of yttrium oxide (yttria) for each 100 moles of zirconium oxide, the two phases, upon X ray diffractometric analysis, being distinct and homogeneously distributed, characterized in that it is obtained by a process comprising the following steps:   a) preparation of a suspension of zirconia stabilized by yttria (YSZ), by dispersing zirconia stabilized by yttria (YSZ), having a particle size of between 1 and 40 m mu , in dimineralized water; b) preparation of a solution of nickel by dissolving a hydrsoluble and thermodecomposable nickel salt in demineralized water; c) mixing of the nickel solution with the dispersion obtained in step (a) and homogenization of the resulting dispersion by magnetic stirring for a time of between 5 and 40 minutes; d) elimination of the water from the dispersion obtained in step (c) by a system capable of operating without, or almost without, decomposition phenomena obtaining a solid consisting of particles of zirconia stabilized by yttra (YSZ) covered with the nickel salt; e) calcination under oxidating conditions of the solid obtained in step (d) to cause the formation of a solid consisting of particles of YSZ covered with nickel oxide; f) treatment with hydrogen of the solid obtained in step (e) to reduce the nickel oxide to metal nickel.
Patent DE-69624224-D1 (DE)
Inventor: JUNG YOUNG CHAE
IPC: C10L5/06
Filed: 1996-12-27
Granted: 2002-11-14
Abstract: PCT No. PCT/KR96/00251 Sec. 371 Date Aug. 28, 1997 Sec. 102(e) Date Aug. 28, 1997 PCT Filed Dec. 27, 1996 PCT Pub. No. WO97/24414 PCT Pub. Date Jul. 10, 1997A method for manufacturing coal agglomerates for use in a direct smelting reducing furnace is disclosed, in which a fine coal is agglomerated at a high temperature in a simple manner, or anthracite or low free swelling coal having a low free swelling index is mixed with the fine coal, and the mixture is agglomerated at a high temperature, thereby turning the low quality coal to useful purpose. The present invention is characterized in that a fine coal having a free swelling index of 3.0 or more and a particle size of 8 mm or less, or the fine coal mixed with 70 weight % of anthracite or a low free swelling coal, is maintained at 600 DEG  C. or over for 5 minutes or more, thereby manufacturing coal agglomerates for use in a direct smelting reducing furnace.
Patent DE-69628338-D1 (DE)
Inventor: MATHERS P
IPC: E01F9/04
Filed: 1996-02-05
Granted: 2003-06-26
Abstract: PCT No. PCT/US96/01584 Sec. 371 Date Feb. 5, 1996 Sec. 102(e) Date Feb. 5, 1996 PCT Filed Feb. 5, 1996 PCT Pub. No. WO97/28471 PCT Pub. Date Aug. 7, 1997All-ceramic retroreflective elements which may be used in pavement markings comprising an opacified ceramic core and ceramic optical elements partially embedded into the core.
Patent DE-69629789-D1 (DE)
Inventor: JINBO MASAYUKI
IPC: C07D295/13
Filed: 1996-12-06
Granted: 2003-10-09
Abstract: A process for preparing a 2-acylamino alcohol derivative which comprises (A) reacting an aminopropanol derivative represented by the following formula (1): Y-CH2-C*H(NHP<1>)-C*H(OH)-R<1> with an amine represented by R<2>H to synthesize an amino alcohol derivative represented by the following formula (2): R<2>-CH2-C*H(NHP<1>)-C*H(OH)-R<1> (B) leaving P<1> from said amino alcohol derivative represented by formula (2) to synthesize an amino alcohol derivative represented by the following formula (3): R<2>-CH2-C*H(NH2)-C*H(OH)-R<1> (C) reacting said amino alcohol derivative represented by formula (3) with a carboxylic acid represented by R<11>COOH or a reactive derivative thereof to prepare a 2-acylamino alcohol derivative represented by the following formula (4): R<2>-CH2-C*H(NHCOR<11>)-C*H(OH)-R<1> wherein * represents an asymmetric carbon atom, and P<1>, R<1>, R<2> and R<11> are defined in the specification. A process for preparing alcohol derivatives having an acylamino group through several steps from amino group-protected 2-aminopropanol derivatives, and novel amino alcohols useful as intermediates in the process for preparing the alcohol derivative.
Patent DE-69713117-D1 (DE)
Inventor: COLLINS RANDALL
IPC: G05D11/13
Filed: 1997-10-09
Granted: 2002-07-11
Abstract: An octane sensitive blending dispenser for fluids, particularly for fuel dispensers. The dispenser controls component pumps according to octane data measured by octane meters. In one form of the invention octane measurements are taken within the input lines connected to the dispenser from fluid storage tanks. Control of the component pumps is accomplished by determining the difference between the desired blend octane and the observed blend octane and adjusting the pumps so as to more closely blend the desired fluid.
Patent DE-69729599-D1 (DE)
Inventor: ZACCHEO ALESSANDRO IVANO
IPC: A61C9/00
Filed: 1997-03-26
Granted: 2004-07-29
Abstract: An impression tray for fixed dental prosthesis, whose main feature is to have a first (5) and a second opposed recesses (8) to contain the material to be impressed, through which both the impressions of the upper and lower side of the dental arcade of a patient can be taken simultaneously. <IMAGE>
Patent DE-69730836-D1 (DE)
Inventor: NEISZ J
IPC: A61B5/08
Filed: 1997-06-25
Granted: 2004-10-28
Abstract: A gain control method for providing a gain controlled signal representative of a periodic physiological parameter of a patient includes providing a signal characteristic of the periodic physiological parameter. The periodic physiological parameter includes a plurality of periodic cycles. Gain of the signal is updated only once per periodic cycle following detection of a periodic event. The updating is performed by monitoring an amplitude of the signal between detection of periodic events and comparing the amplitude to a gain control amplitude threshold. Gain of the signal is updated as a function of the comparison. Further, gain is updated following expiration of a predetermined period of time if a periodic event is not detected within the predetermined period of time. The physiological parameter may be respiratory effort. An apparatus for providing such gain control is also provided.
Patent DE-69733217-D1 (DE)
Inventor: VISSER DIRK
IPC: E04C2/292
Filed: 1997-11-28
Granted: 2005-06-09
Abstract: A building element (1) comprising an outer sheath and an inner core, the sheath being formed of a material having a greater tensile strength than compressive strength and the core having a greater compressive strength than tensile strength; wherein the outer sheath is longitudinally extending and has a first face (7) and a second face (8) which are spaced apart, first (9) and second (21) edges and a first and second end; wherein the first face (7) and the second face (8) are joined at the first (9) and second (21) edges to form the outer sheath as a continuous body, and wherein the first edge (9) and the second edge (21) are so shaped that the first edge (9) of one such building element (1) is adapted to locate in the second edge (21) of another such building element (1).
Patent DE-69804650-D1 (DE)
Inventor: BROWN W
IPC: C09G1/16
Filed: 1998-10-22
Granted: 2002-05-08
Abstract: An emulsion polish that includes a non-volatile silicone fluid, a liquid polyether siloxane immiscible with water and the silicone fluid, and a surfactant to stabilize the emulsion. The polyether siloxane has a specific gravity less than that of the silicone fluid. A process for treating a hard surface with such a polish is also disclosed.
Patent DE-69809288-D1 (DE)
Inventor: KUNSTREICH SIEBO
IPC: B22D11/11
Filed: 1998-12-01
Granted: 2002-12-12
Abstract: Both an apparatus and method are provided for electromagnetically braking a flow of molten metal during a continuous casting operation. The apparatus includes an electric electromagnetic inductor of the traveling-magnetic-field polyphase stator-type connected to a source of electrical power. The inductor is mounted on a casting plant opposite one face of the product being cast, and has two or three phase windings. The electrical power supply of the apparatus includes two or three elementary DC sources, each of which can be adjusted in terms of current intensity independent of one another. Each of the elementary electrical DC sources is connected to one, and only one of the phase windings of the inductor. The arrangement of the apparatus allows a flow of molten, ferromagnetic metal such as steel to be adjustably braked by merely adjusting the parameters of the source of electrical supply.
Patent DE-69813863-D1 (DE)
Inventor: STEVENS H
IPC: B23K26/08
Filed: 1998-10-14
Granted: 2003-05-28
Abstract: A method and apparatus for reducing, capturing and disposing of the waste start up web of paper in high-speed manufacturing procedures which involve a converting step, e.g. laser perforation or the like. Specifically, the converting apparatus and the web speed are carefully and precisely controlled by a programmable logic controller to result in a rapid production of converted web with a minimum of waste. The apparatus and method are tuned by sampling the waste and web for conversion quality, and using that information to adjust the converting apparatus and bias that adjustment for maximum reduction in waste.
Patent DE-69816645-D1 (DE)
Inventor: BORDERS L
IPC: H04W68/00
Filed: 1998-11-06
Granted: 2003-08-28
Abstract: A medical device controller (40) for controlling a surgical table having a controllable articulated frame (58) and a controllable surface (60) coupled to the frame is provided. The controller includes a handheld housing (114), a display (116), and a processor (106). The processor is configured to provide indicia on the display indicative of a user command to move the articulated frame to a desired frame configuration and to command the articulated frame to move to the desired frame configuration based on a user input. The processor is further configured to provide indicia on the display indicative of a user command to adjust the controllable surface to a desired surface configuration and to command the surface to adjust to the desired surface configuration based on a user input. <IMAGE>
Patent DE-69829316-D1 (DE)
Inventor: PHILLIPS NIGEL C
IPC: A61K31/70
Filed: 1998-12-22
Granted: 2005-04-14
Abstract: The present invention relates to a composition and method for treating cancer in the urinary bladder. More particularly, the present invention relates to a composition comprising a Mycobacterium phlei (M. phlei) deoxyribonucleic acid (M-DNA)-M. phlei cell wall complex (MCC), wherein the M-DNA is preserved and complexed on the M. phlei cell wall, and a pharmaceutically acceptable carrier. The MCC composition inhibits proliferation of and induces apoptosis in the cancer cells in the urinary bladder of the animal.
Patent DE-69831231-D1 (DE)
Inventor: WALLACH DAVID
IPC: C12N5/10
Filed: 1998-06-01
Granted: 2005-09-22
Abstract: A B1 protein, its isoforms, analogs, fragments and derivatives, DNA encoding it and recombinant production are provided. The protein is useful in the modulation of intracellular inflammation, cell death and/or cell survival pathways.
Patent DE-69832410-D1 (DE)
Inventor: WINGARD ERIC
IPC: G06F13/42
Filed: 1998-07-22
Granted: 2005-12-22
Abstract: The present invention provides for an on-chip communications method with fully distributed control combining a fully-pipelined, fixed-latency, synchronous bus with a two-level arbitration scheme where the first level of arbitration is a framed, time-division-multiplexing arbitration scheme and the second level is a fairly-allocated round-robin scheme implemented using a token-passing mechanism. Both the latency and the bandwidth allocation are software programmable in real-time operation of the system. The present invention also provides for a communications system where access to a shared resource is controlled by the above communications protocol. Access to and from the shared resource from the subsystem is through a bus interface module. The bus interface modules provide a level of indirection between the subsystem to be connected and the shared resource. This allows the decoupling of system performance requirements from subsystem requirements. Communication over the bus is fully memory mapped.
Patent DE-69833798-D1 (DE)
Inventor: GREENWALD B
IPC: A61K31/135
Filed: 1998-12-29
Granted: 2006-05-04
Abstract: The present invention is directed to double prodrugs containing polymeric-based transport forms. These polymeric prodrugs are preferably of the formula: wherein: B is a leaving group or a residue of an amine-containing target moiety; G is or CH2; Y1-2 are independently O or S; M is X or Q; where X is an electron withdrawing group and Q is a moiety containing a free electron pair positioned three to six atoms from C(=Y2); R1, R4, R7, R8, R9, R10 and R13 are independently selected from the group consisting of hydrogen, C1-6 alkyls, C3-12 branched alkyls, C3-8 cycloalkyls, C1-6 substituted alkyls, C3-8 substituted cycloalkyls, aryls, substituted aryls, aralkyls, C1-6 heteroalkyls, substituted C1-6 heteroalkyls; R2, R3, R5 and R6 are independently selected from the group consisting of hydrogen, C1-6 alkyls, C1-6 alkoxy, phenoxy, C1-8 heteroalkyls, C1-8 heteroalkoxy, substituted C1-6 alkyls, C3-8 cycloalkyls, C3-8 substituted cycloalkyls, aralkyls, aryls, substituted aryls, such as aryls substituted with halo-, nitro- and cyano-; carboxy-, C1-6 carboxyalkyls and C1-6 alkyl carbonyls; (m) is zero or one; (n) is zero or a positive integer; (p) is zero, one or two; and R11 is a substantially non-antigenic polymer. The first prodrug is generated when the polymeric portion of the double prodrug is cleaved and the parent molecule is generated rapidly thereafter in vivo, as a result of a trialkyl lock type lactonization-type reaction.
Patent DE-69835741-D1 (DE)
Inventor: HEERY MICHAEL
IPC: A61P29/00
Filed: 1998-04-28
Granted: 2006-10-12
Abstract: A method for identifying inhibitor compounds capable of reducing the interaction between a first region which is a signature motif on a nuclear protein, and a second region which is that part of a nuclear receptor which is capable of interacting with the nuclear protein through binding to the signature motif, wherein: the nuclear protein is a bridging factor that is responsible for the interaction between a liganded nuclear receptor and a transcription initiation complex involved in regulation of gene expression; the nuclear receptor is a transcription factor, the signature motif is a short sequence of amino acid residues which is the key structural element of a nuclear protein which binds to a liganded nuclear receptor as part of the process of the activation or repression of target genes.
Patent DE-69838576-D1 (DE)
Inventor: IGAKI KEIJI
IPC: A61B17/072
Filed: 1998-03-31
Granted: 2007-11-29
Abstract: A medical suture holding member loaded in use on an automatic sewing device having a staple line. The suture holding member includes a main body portion of a holding member molded integrally to a tubular shape from a natural or synthetic high molecular material and having an opening on its proximal end for enabling loading of the main body portion of the holding member on a sewing unit of the automatic sewing device. The suture holding member is molded to a tubular shape opened at its distal end to eliminate offsetting otherwise caused on contraction in the inserting direction at the time of insertion of the suture holding member into the automatic sewing device. When the suture holding member is inserted on the automatic sewing device, the entire surface of a loading portion is covered by the suture holding member such that the suture holding member can be reliably positioned at a sewing position in the living body. The suture holding member is prevented from being detached from the sewing device by provision of a detachment preventative unit in the main body portion. <IMAGE>
Patent DE-69839123-D1 (DE)
Inventor: LAUS REINER
IPC: C12P21/08
Filed: 1998-08-18
Granted: 2008-03-27
Abstract: The present invention is directed to novel polynucleotides and the polypeptides encoded by them, each of which are specific to human prostate tumor cells. The present invention further provides chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, and antibodies which bind to the polypeptides of the present invention. Also provided herein are methods for producing the polypeptides of the present invention, as are detection assays that detect the presence of tumor cells in tissue or bodily fluid samples and methods for identifying novel compositions which modulate the activity of prostate tumor antigens and the use of such compositions in diagnosis and treatment of disease.
Patent DE-69840914-D1 (DE)
Inventor: SPEAKMAN STUART
IPC: H01L21/44
Filed: 1998-10-14
Granted: 2009-07-30
Abstract: A method of forming an electronic circuit component using the technique of drop on demand printing to deposit droplets of deposition material, said method comprising depositing a plurality of droplets on a surface to form a patterned electronic device comprising multiple discrete portions.
Patent DE-69908059-D1 (DE)
Inventor: PERRIN ERIC
IPC: B22D11/053
Filed: 1999-09-09
Granted: 2003-06-26
Abstract: PURPOSE: A mold design for a hot-top continuous casting device is provided to suit to add a sound or a vibration of supersonic waves to the mold, and to have the reliability needed to cast in many numbers. CONSTITUTION: A mold is equipped a side projection(18) located a metal unit(1) under an upper part(19) and integrally produced with the metal unit(1). A cooling channel(20) is processed between the upper part(19) and the projection(18), and closed by a collar(21). The collar is fixed in the metal unit(1) with two welding points generated by an electronic line. One of the welding points(22) is made in the upper part(19) of the metal unit(1), that is on a point processed the channel(20). The other welding point(23) is made on the upper face of the projection(18). The welding points(22,23) are received lower thermal and mechanical tension than existing welding points. And closer welding point(22) in a metal of high temperature is reduced the enduring mechanical tension by separating from emitters(25,26) more or less.