baber/WOPTO huggingface dataset:
Patent DE-69121480-D1 (DE)
Inventor: DANIELSON SUSAN JEAN
IPC: G01N33/545
Filed: 1991-06-14
Granted: 1996-09-26
Abstract: Useful materials for diagnostic tests, affinity chromatography, enzymatic reactions and immunoassays are prepared by covalently attaching reactive compounds containing reactive amino or sulfhydryl groups to polymeric particles having pendant carboxyl groups on the outer surfaces. Such reactive compounds include biologically reactive species, including enzymes, polypeptides and proteins. This attachment is carried out using specific carbamoylonium compounds, namely certain 1-(1-pyrrolidinylcarbonyl)pyridinium salts. These compounds react with the carboxyl groups on the particles to form intermediate reactive groups which then react with the amino or sulfhydryl groups to form a covalent linkage between particle and reactive compound. A kit comprises polymeric particles having carboxyl groups on the outer surfaces, and a 1-(1-pyrrolidinylcarbonyl)pyridinium salt.
Patent DE-69123548-D1 (DE)
Inventor: ZINI ROBERTO
IPC: A61B5/308
Filed: 1991-10-02
Granted: 1997-01-23
Abstract: The connecting cable uses a multiple-core, multiple-screen strap (1) which is provided at one end with a terminal (6) within which are dischargers (12) for protection against excess voltages and with a connector (13) for removable connection to the electrocardiograph. At two intermediate points, with a suitable distance between them, the strap (1) is provided with clamps (7,8) from which are branched the separate leads (C1,C2,C9,C10;C3...C8) for the peripheral and precordial branches. The leads (C1...C10) are provided at their free ends with plugs (9) for connection to the measuring electrodes, and electrical resistors for protection against excess voltages are preferably housed in the bodies of said plugs (9). <IMAGE>
Patent DE-69129118-D1 (DE)
Inventor: ELLWOOD DEREK CLIFFORD
IPC: C12R1/46
Filed: 1991-11-04
Granted: 1998-04-23
Abstract: PCT No. PCT/GB91/01927 Sec. 371 Date Jul. 6, 1993 Sec. 102(e) Date Jul. 6, 1993 PCT Filed Nov. 4, 1991 PCT Pub. No. WO92/08799 PCT Pub. Date May 29, 1992.A process for the production of hyaluronic acid by continuous fermentation of Streptococcus equi in a chemostat culture gives high yields of high molecular weight hyaluronic acid uncontaminated by toxic impurities. The process is advantageous in that it solves the problem of traditional batch culture in which degradation enzymes can begin to break down the cell walls of Streptococcus releasing cell contents into the fermenter broth, leading to purification difficulties.
Patent DE-69133325-D1 (DE)
Inventor: COLE A
IPC: A61P43/00
Filed: 1991-06-17
Granted: 2003-11-13
Abstract: Method using tetra-aryl porphyrins for and, in particular, 5,10,15,20-tetrakis(4-carboxyphenyl)porphine as a fluorescent tracer for cancers of the lung, and as a radiotracer therefor as a complex with 67Cu. The latter complex also provides a source of beta radiation for selective destruction of lung malignancies as well as gamma radiation useful for image analysis of the situs thereof by single photon emission computed tomography, as an example, both in vivo. Copper-64 may be substituted for the 67Cu if only radiotracer characteristics are of interest. This lighter isotope of copper is a positron emitter, and positron emission tomography techniques can be used to locate the malignant tissue mass.
Patent DE-69202483-D1 (DE)
Inventor: MOROZUMI MANAMI
IPC: C07H19/167
Filed: 1992-02-10
Granted: 1995-06-22
Abstract: The present invention provides two kinds of solid 2-octynyl adenosine products with novel properties which are stabilized with respect to temperature or temperature and humidity, one being solid 2-octynyl adenosine having a moisture content of not more than 3%, and the other being solid 2-octynyl adenosine deposited from an anhydrous alcoholic solution or hydrous alcoholic solution of 2-octynyl adenosine, said hydrous alcoholic solution having a water content of less than 1%.
Patent DE-69206323-D1 (DE)
Inventor: SCHOUBYE PETER
IPC: B01J23/40
Filed: 1992-05-22
Granted: 1996-01-11
Abstract: Process for the regeneration of spent sulphuric acid from chemical processes, which process comprises the steps of evaporating and decomposing the spent sulphuric acid at a temperature of 400-800 DEG C with excess of air, to a gas mainly consisting of carbon dioxide, steam, nitrogen, oxygen, sulphur dioxide and sulphur trioxide together with minor amounts of ammonia, carbon monoxide, residual organic compounds and dust from solids in the spent acid; cooling the gas to 360-450 DEG C and oxidizing oxidizable components in the cooled gas by contact with an oxidation catalyst; cooling the oxidized gas to a temperature of 10-50 DEG C above the sulphuric acid dew point in the gas and condensing sulphuric acid formed in the cooled and oxidized gas. <IMAGE>
Patent DE-69212256-D1 (DE)
Inventor: ELLIOTT BARRY JAMES
IPC: G08B17/06
Filed: 1992-08-26
Granted: 1996-08-22
Abstract: A heat-detector cable comprises first and second digital heat-detector elements assembled in close proximity, each comprising a pair of conductors biassed towards each other but normally prevented from contacting by a coating of a fusible insulating material on at least one of them, the response characteristics of the said first and second elements on exposure to hazardous temperatures differing such that the first said element responds sooner than the second. Preferably the fusible materials have substantially different softening temperatures, that in the first element having the lower softening temperature. Fire or overtemperature conditions can be distinguished from faults by the difference in response times. <IMAGE>
Patent DE-69214104-D1 (DE)
Inventor: ZELVERTE ALAIN
IPC: H01M10/54
Filed: 1992-12-07
Granted: 1996-10-31
Abstract: The invention relates to a machine for the treatment of electrolyte from spent lead-acid batteries, comprising a tank for receiving the electrolyte transferring the electrolyte to a reactor (4), a detector (15) of the pH of the contents of the reactor, means for introducing a neutralising reagent into the reactor until the desired pH value is obtained, means for introducing a flocculant for the lead into the reactor, means enabling the contents of the reactor to be transferred, after neutralisation and flocculation, to a drainable decanter (13). <IMAGE>
Patent DE-69220701-D1 (DE)
Inventor: ZEITLIN ANDREW L
IPC: C12P13/04
Filed: 1992-03-19
Granted: 1997-08-14
Abstract: Mixtures of enantiomeric D,L-threo 2-amino-3-hydroxy-3-phenylpropionic acids can be stereoisomerically enriched by contacting the mixture with a D-threonine aldolase. In a typical embodiment, D- and L-threo 2-amino-3-hydroxy-3-(4-methylsulfonylphenyl)propionic acid is treated with D-threonine aldolase to produce L-threo 2-amino-3-hydroxy-3-(4-methylsulfonylphenyl)propionic acid with a high ee. The benzaldehyde and amino acid formed from the D-threo isomer can be recycled.
Patent DE-69232064-D1 (DE)
Inventor: GAETA S
IPC: A61K38/12
Filed: 1992-11-19
Granted: 2001-10-25
Abstract: (A) An agonist analogue of amylin having aminoacid sequence (I) is claimed. In (I) A1 is Lys, Ala, Ser or H; B1 is Ala, Ser or Thr; C1 is Val, Leu or Ile; D1 is His or Arg; E1 is Ser or Thr; F1 is Ser, Thr, Gla or Asn; G1 is Asn, Gln or His; H1 is Phe, Leu or Tyr; I1 is Ala or Pro; J1 is Ile, Val, Ala or Leu; K1 is Ser, Pro, Leu, Ile or Thr; L1 is Ser, Pro or Thr; M1 is Asn, Asp, Gln or Asn; X, Y are residues having side chains which are chemically bonded to each other to form an intramolecular linkage; and Z is amino, alkylamino, dialkylamino, cycloalkylamino, arylamino, aralkylamino, alkoxy, aryloxy or aralkyloxy, with provisos. The peptides are pref. prepd. by solid phase synthesis. Pref. peptides include 25,28,29 Pro-h-amylin (Ia), des-'Lys 25,28,29 Pro-h-amylia and 18 Arg 25,28 Pro-h-amylin.
Patent DE-69317716-D1 (DE)
Inventor: HORROBIN DAVID FREDERICK
IPC: A61K31/23
Filed: 1993-08-16
Granted: 1998-05-07
Abstract: Prevention and/or treatment of abnormal calcification in any tissue by the administration of (i) GLA and/or its EFA metabolites, and in particular the rapidly produced DGLA and/or (ii) EPA and/or its precursors, stearidonic acid and 20:4 n-3, and metabolites, docosahexaenoic acid (DHA) or docosapentaenoic acid (22:5 n-3), as such or in salt or other pharmacologically acceptable form. This is especially suitable for prevention or treatment of nephrocalcinosis and/or renal stones.
Patent DE-69323292-D1 (DE)
Inventor: SANTAGIULIANA EVANS
IPC: B65D83/06
Filed: 1993-10-29
Granted: 1999-03-11
Abstract: PCT No. PCT/EP93/03030 Sec. 371 Date Jun. 10, 1994 Sec. 102(e) Date Jun. 10, 1994 PCT Filed Oct. 29, 1993 PCT Pub. No. WO94/10541 PCT Pub. Date May 11, 1994.A measuring and dispensing device for granular powder materials as disclosed. The device includes a first element having a holding chamber and a collecting chamber joined by an interconnecting wall having an opening. A second element is located within the first element and has an outer wall which faces an inner wall of the first element for defining a dispensing duct. The second element has a measuring chamber having an open bottom and another opening connected with the first opening of the first element. A lid applied to the upper part of the first element and has an opening communicating with the dispensing duct to allow for the dispensing of product. The first and second elements have wall portions that converge towards the bottom.
Patent DE-69403084-D1 (DE)
Inventor: MACKENZIE ALEXANDRA
IPC: C07D493/04
Filed: 1994-07-18
Granted: 1997-06-12
Abstract: A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein X, O R, R1, R2, R3, and R4 are defined in the specification; compositions containing such compounds; intermediates used in the preparation of such compounds; and methods for treating a disease associated with the altered tone and/or motility of smooth muscle, for example chronic obstructive airways disease, asthma, urinary incontinence, irritable bowel syndrome, diverticular disease, oesophageal achalasia, and hypertension.
Patent DE-69403960-D1 (DE)
Title: Arylalkansäuretrennung
Inventor: WARNECK JULIE BELINDA HAZEL
IPC: C12P41/00
Filed: 1994-03-03
Granted: 1997-07-31
Abstract: An organism of the genus Ophiostoma or Ceratocystis, or a material having enzymatic activity derived therefrom, is used as a stereo-specific agent, in a biotransformation reaction, for the production of (S &cir& _)-ketoprofen from a mixture of enantiomers of an ester thereof.
Patent DE-69410601-D1 (DE)
Inventor: NGUYEN PHU
IPC: H01B7/18
Filed: 1994-02-14
Granted: 1998-07-02
Abstract: This invention relates to multi-component assemblies comprising a plurality of substantially parallel insulated conductors and or cables at least one of which is wrapped in a flexible affixment means thereby enabling the wrapped component to be secured to a support substrate.
Patent DE-69411807-D1 (DE)
Inventor: NEFF ROGER EDGAR
IPC: C02F1/56
Filed: 1994-05-16
Granted: 1998-08-27
Abstract: Dispersions of finely divided high molecular weight polyacrylamide particles are formed and treated with a caustic material to hydrolyze the polymer without undesirable side chain reactions to form high molecular weight anionic acrylamide polymers. A preferred technique for forming these products comprises the formation of a stabilized water-in-oil emulsion of aqueous acrylamide monomer, polymerizing the monomer, reacting the polymer emulsion thus formed with a hydrolysis agent and inverting the resultant hydrolyzed polymers into solution. These materials are useful in a variety of industrial applications for removing particulates from effluent streams.
Patent DE-69415266-D1 (DE)
Inventor: KOBAYASHI HIROFUMI
IPC: D02G3/32
Filed: 1994-10-13
Granted: 1999-01-28
Abstract: An every course hose (10) is produced by knitting substantially exclusively a covered elastic yarn (1) into the leg portion (15) knitting fabric thereof. A covering yarn (3a) is wound around an elastic yarn (2) as the core yarn to form the covered elastic yarn (1). The covering yarn (2a) is constituted of a plurality of filaments made of a polyamide substantially free from titanium oxide and having a flat cross section with a flatness (b/a) (the ratio of the length b to the width a) of 2.0 to 6.0. <IMAGE>
Patent DE-69420592-D1 (DE)
Inventor: BERTOLOTTO ANTONIO
IPC: B09B1/00
Filed: 1994-01-13
Granted: 1999-10-21
Abstract: Plant for recovery and disposal of solid urban and assimilable waste which is capable in particular of being arranged in small insular or mountain communities and requires one single site for depositing the waste which is reduced into compacted blocks and stored so that, after subdivision of said site into any number of structures, it is possible - at the end of the cycle of production of the biogas brought about by the natural transformation of the waste which is kept under optimum conditions thanks to the addition of liquid manure and after recovery and possible recycling of the ooze - to recover the volume of waste introduced into the first structure which it will consequently be possible to reuse, in the same way as the waste - from now on formed from an organic fraction (mould) and an inert fraction - and the biogas generated in the meantime. <IMAGE>
Patent DE-69425265-D1 (DE)
Inventor: OLOFSSON HANS
IPC: A01J7/00
Filed: 1994-09-14
Granted: 2000-08-17
Abstract: A device for automatic removal of milking equipment from an animal's udder, comprising a motor (1) and a removal member (3) rotatable by the motor. According to the invention, a coupling device (K) is adapted to keep the removal member (3) operably connected to the motor and to keep the removal means disconnected from the motor, respectively.
Patent DE-69428716-D1 (DE)
Inventor: BACS ARON JR
IPC: G09G3/02
Filed: 1994-06-28
Granted: 2001-11-22
Abstract: A projection system for projecting computergraphic images onto a domed or spherical viewing surface. An intense beam of coherent light is color and intensity modulated and deflected in a pair of cartesian axes prior to being projected through a wide angle lens array. Because the light beam is deflected before entering the wide angle lens array, greater angles of deflection are possible. The images are generated by rapidly changing the deflection of an intense spot of light which is projected onto the viewing surface at a rate above the viewer's flicker rate. This wide angle lens array may include a scan flattening lens array by which the image can be focused onto a spatial image focal plane before it is projected through a wide angle lens.
Patent DE-69433220-D1 (DE)
Inventor: BOUILLON ROGER
IPC: C07C401/00
Filed: 1994-07-07
Granted: 2003-11-06
Abstract: The present invention relates to analogues of vitamin D, which lack the combined presence of the trans-fused six-membered C-ring and of five-membered D-ring, but still possess a central part consisting of a substituted chain of five atoms, atoms which correspond to positions 8, 14, 13, 17 and 20 of vitamin D, and at the ends of which are connected, at position 20 a structural moiety representing part of the side-chain of vitamin D or of an analogue of vitamin D, and at position 8 the  DELTA (5,7)-diene moiety connected to the A-ring of the active 1-alpha-hydroxy metabolite or of an established vitamin D analogue, to their preparation process, to pharmaceutical preparations comprising these compounds and to their use in medicine.
Patent DE-69433379-D1 (DE)
Inventor: HORNE DAVID A
IPC: C07D405/00
Filed: 1994-04-08
Granted: 2004-01-15
Abstract: The subject invention provides a bicyclic aminoimidazole compound, a hydroxyalkyl aminoimidazole compound, a bicyclic pyrrole compound, a hymenin compound, an aldehyde aminoimidazole compound, a ketal aminoimidazole compound, a tricyclic compound, and a tetrahydropurine compound. The subject invention also provides for processes for preparing the compounds.
Patent DE-69434599-D1 (DE)
Inventor: LEE HELEN TSENWHEI
IPC: C07D405/12
Filed: 1994-02-08
Granted: 2006-03-30
Abstract: Pharmaceutically useful compounds having ACAT inhibitory activity of the formula <CHEM> wherein n is 0, 1, or 2, for X other than tetrazole and n = 2 then R2 = R3 = H; R1 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, a heteroaromatic group or a hydrocarbon group having from one to 18 carbon atoms; R2 and R3 are hydrogen, halo, hydroxy, alkyl, alkenyl, cycloalkyl, phenyl, substituted phenyl, a heteroaryl, or form a spiroalkyl group; x is a 5-membered heteromonocyclic group containing at least one to four heteroatoms selected from the group consisting of isothiazole, oxazole, thiazole, imidazole, furan, thiophene, pyrrole, tetrazole, 1,2,3-triazole, 1,2,4-oxadiazole, 1,3,4-oxadiazole, 1,3,4-thiadiazole, 1,2,4-triazole, and 1,2,4-oxadiazole said heteromonocyclic group being unsubstituted or substituted at any available position along the ring,
Patent DE-69500156-D1 (DE)
Inventor: SEKINE YASUO
IPC: C07D471/04
Filed: 1995-04-18
Granted: 1997-03-27
Abstract: An imidazopyridine derivative of the formula [I]: <CHEM> wherein R<1> is a lower alkyl group, R<2> is a lower alkanoyl group, and R<3> and R<4> are each lower alkyl groups, or both combine at the end thereof to form an alkylene group having 3 to 6 carbon atoms, and a pharmaceutically acceptable salt thereof, said imidazopyridine derivatives have an excellent angiotensin II antagonistic activity and are useful for the prophylaxis or treatment of hypertension.
Patent DE-69502534-D1 (DE)
Inventor: NORMAN C LEE
IPC: B65F1/14
Filed: 1995-04-27
Granted: 1998-06-25
Abstract: A wheeled refuse container (10) adapted to be nestable with like containers for storage and shipment comprises a container body (12) having a closed lower end (18) and an open upper end providing access to an interior refuse-receiving area (20). A pair of wheels (22) are mounted to the container body rearwardly adjacent its lower end by a pivoting axle assembly (30,32,34) for selective movement of the wheels between a retracted position, wherein the wheels do not interfere with nested insertion of the lower end of the container body into a like container, and an operable position, wherein the wheels are disposed laterally outwardly of the container body for stable rotational rolling support thereof. <IMAGE>
Patent DE-69506394-D1 (DE)
Inventor: SIMPSON WILLIAM JOHN
IPC: C12Q1/66
Filed: 1995-04-06
Granted: 1999-01-14
Abstract: PCT No. PCT/GB95/00794 Sec. 371 Date Apr. 7, 1997 Sec. 102(e) Date Apr. 7, 1997 PCT Filed Apr. 6, 1995 PCT Pub. No. WO95/27797 PCT Pub. Date Oct. 19, 1995Methods for internally and externally photostandardizing chemical assays, e.g. an ATP-bioluminescence assay. A pre-determined amount of a photosensitive derivative of the analyte of interest is used in the assay protocol which releases a known amount of the free analyte when it is exposed to a flash of visible light of pre-determined duration and intensity. By monitoring the response of a test property of the assay to the release of a known quantity of analyte, a standard value can be calculated which allows either direct determination of the amount of analyte originally present in the assayed sample or production of a photocalibration series against which results of an assayed sample can be compared.
Patent DE-69508295-D1 (DE)
Inventor: COLAVIN OSWALD
IPC: G06F11/22
Filed: 1995-01-25
Granted: 1999-04-22
Abstract: The processing circuit (9) used for treating images has a host interface (7) which allows its bus (6) access to and from an external information system (8). The processing circuits are divided into three blocks (1,2,3) connected by the bus (6). Test registers (4,5) are also connected to the bus (6) and interposed between upstream and downstream blocks. The test registers which have active and rest states are each identified by an address which enables data to be sent to them or the data stored in them to be read.
Patent DE-69520362-D1 (DE)
Inventor: BARRAUD GEORGE
IPC: H04N7/173
Filed: 1995-08-01
Granted: 2001-04-19
Abstract: A user terminal exchanges information with a server through a transmission medium. A coupling unit couples the user terminal to the transmission medium in accordance with information from the server. Likewise, the server is controlled in accordance with information from the user terminal. In this manner, communication is created and performed between the server and the user terminal. The user terminal may be a Set-Top Unit which may be adjusted to the transmission medium by, for example, a physical medium converter or the communication itself between the Set-Top Unit and the server may be adjusted as directed by programs installed in the Set-Top Unit which may originate from the server.
Patent DE-69521672-D1 (DE)
Inventor: LOVE WILLIAM G
IPC: A61K41/00
Filed: 1995-12-14
Granted: 2001-08-16
Abstract: A topically administrable pharmaceutical composition comprising (A) zinc phthalocyanine, (B) as carrier for (A), (i) a monoalkyl ether of diethyleneglycol substantially in the absence of a N-alkylpyrrolidone, a N,N-dialkylbenzamide or dimethyl sulphoxide, or (ii) a mixture of a monoalkyl ether of diethyleneglycol with a lipid and (C) a gelling agent.
Patent DE-69526918-D1 (DE)
Inventor: SAKAI TETSUO
IPC: C07D475/04
Filed: 1995-08-04
Granted: 2002-07-11
Abstract: A remedy for spinocerebellar degeneration containing a compound represented by general formula (I) or a pharmaceutically acceptable salt thereof as the active ingredient, wherein R<1> and R<2> represent each hydrogen or they are combined together to represent a single bond; and R<3> represents -CH(OH)CH(CH)CH3, - CH(OCOCH3)CH(OCOCH3)CH3, -CH3, -CH2OH or phenyl when R<1> and R<2> represent each hydrogen, while R<3> represents -COCH(OH)CH3 when R<1> and R<2> together represent a single bond. <CHEM>
Patent DE-69533291-D1 (DE)
Inventor: WHITEFIELD KEVIN
IPC: H02K7/14
Filed: 1995-11-06
Granted: 2004-08-26
Abstract: A rotary pump which is suitable for use as the pump for a vehicle power steering system has an integral motor. The pump includes a housing 16 through which a rotatable shaft 4 extends having at one end a pump rotor assembly 5. The pump rotor assembly 5 is in fluid communication with an oil cavity 15 which is in good thermal contact with the housing 16. The housing 16 functions as a heat sink. Mounted on the radially outer wall of the housing 16 is the stator 20 of the motor with the stator 20 also in good thermal contact with the housing 16. The rotor 26 of the motor is located radially outside of the stator 20 and has axially arranged magnets 27. The rotor 26 is connected to the rotatable shaft 4 by means of a radially extending wall 26b. The integral rotary pump and motor is very compact and straightforward to construct and is also capable of withstanding the heat generated by the motor components during the high demands of a vehicle steering system. <IMAGE>
Patent DE-69627175-D1 (DE)
Inventor: AMRANI EL HASSAN
IPC: G01N27/02
Filed: 1996-11-18
Granted: 2003-05-08
Abstract: There is disclosed a method for interrogating a sensor comprising the steps: applying a periodic electrical signal to the sensor; obtaining a signal therefrom; and performing an operation on the obtained signal to obtain the sensor response at a plurality of frequencies, said operation including a transformation to the frequency domain of said signal or a quantity related to said signal.