baber/WOPTO huggingface dataset:
Patent EP-0862622-B1 (EP)
Inventor: HEMMINGS BRIAN ARTHUR
IPC: A61P3/00
Filed: 1996-11-05
Granted: 2004-08-18
Abstract: The invention concerns RAC-PK protein kinase and fragments thereof, as well as activators and inhibitors of RAC-PK protein kinase for use as medicaments, particularly in the treatment of diseases concerned with abnormalities in processes modulated by insulin, such as cellular proliferation, insulin deficiency and/or excess blood sugar levels. Moreover, the invention provides RAC-PK protein kinase for use in screening potential mimics or modulators thereof. The invention further provides a screening kit comprising the RAC-PK as an active principle, and a method for screening compounds which are candidate mimics or modulators of RAC-PK activity comprising detecting specific interactions between the candidate compounds and RAC-PK.
Patent EP-0869784-B1 (EP)
Inventor: KUHAJDA FRANCIS P
IPC: A61K31/365
Filed: 1996-11-15
Granted: 2005-08-31
Abstract: Weight loss was noted in nude mice treated with cerulenin, a non-competitive inhibitor of FAS. Sustained reduction of adipocyte mass in humans without toxicity would significantly impact disease prevention worldwide. Aside from psychological and self-esteem improvement, weight loss via reduction of adipocyte mass may: (1) ameliorate hyperglycemia associated with non-insulin-dependent diabetes mellitus thereby reducing diabetic complications such as arterial disease, blindness, cataracts, etc., (2) reduce hypertension, (3) reduce risk of coronary artery vascular disease and stroke, and (4) reduce the risk of other complications of massive obesity such as osteoarthritis, surgical complications, etc. There is also potential use in livestock and poultry to reduce the saturated fat content of meat products. Therefore FAS inhibitors are disclosed herein as novel agents for weight reduction. A family of compounds ( gamma -substituted- alpha -methylene- beta -carboxy- gamma -butyrolactones) whose synthesis was based on the cerulenin motif is shown herein to inhibit fatty acid synthesis, inhibit growth in certain susceptible tumor cells, and induce weight loss.
Patent EP-0786493-B1 (EP)
Inventor: LABAUZE GERARD
IPC: C08K5/544
Filed: 1997-01-15
Granted: 2001-05-09
Abstract: A sulphur-vulcanisable rubber composition comprises at least one functionalised or modified dienic polymer with carbon black or silica as filler. The dienic polymer is a functionalised polymer with a silanol or a polysiloxane block with a terminal silanol at the chain end or modified along the length of the chain by silanol groups. The composition further comprises an organosilane having an amine or imine group of formula (Z)-R1-Si(OR2)3-n(R3)n (I), where Z = a primary amine, secondary cyclic amine or an imine or a polyamine; R1, R2, R3 = optionally different, 1-12 C, preferably, 1-4 C alkoyl, aryl, alkaryl, or aralkyl; n = 0, 1 or 2. Also claimed are: (i) a process for the preparation of the rubber composition; (ii) a tyre having improved frictional resistance comprising the rubber composition; and (iii) a tyre tread consisting of the rubber composition.
Patent EP-0817450-B1 (EP)
Inventor: STROEMMER KLAUS
IPC: H04B1/3888
Filed: 1997-06-25
Granted: 2003-10-29
Abstract: The case shape matches the shape of the telephone and is in close contact with the telephone in the region of its charging contacts (15). In this region the case is made of very thin material and has at least one opening (23), enabling the telephone to be placed on a charging station (12). The thickness of the material in the region of the contacts is less than the spring travel of the electrical contacts (13). The opening encloses the region of the electrical contacts or extends over the entire region of the telephone in which the contacts are arranged.
Patent EP-0861957-B1 (EP)
Inventor: STEFANESCU ALEXANDER
IPC: E05B19/00
Filed: 1997-11-05
Granted: 2003-07-23
Abstract: The key shaft has a basic profile with T-shaped cross-section. The T-bar forms a guide arm with guide surfaces. The vertical T stem running along the lengthwise centre plane forms the breast at the end side, and possesses broad side surfaces for forming profiled ridges which have curved cross-sectional outlines. The opposite-facing broad side surfaces (5,6) each form at least one longitudinal groove (7,8) with a groove-base protruding beyond the lengthwise centre plane (M-M). The sides of the groove and the breast surface (4) run in a circle or ellipse at a tangent from the broad side surfaces.
Patent EP-0784926-B1 (EP)
Inventor: TIMMERMANS HUBERTUS RENIER MAR
IPC: A01K1/06
Filed: 1997-01-17
Granted: 2000-03-22
Abstract: Feed barrier (1) with a plurality of adjacent fodder openings for livestock, comprising two beams which determine an upper beam (4) and a lower beam (5), and which extend substantially horizontally and which are mutually connected by means of a plurality of regularly horizontally spaced connecting posts (6,14), each fodder opening being bound to one side by a tilting tube (7) and bound to the other side by a boundary post (14), the tilting tubes (7) being tiltable about a horizontal hinge axis (9) extending transverse to the feed barrier between at least one inclined access position, in which they define with a boundary post (14) above the hinge axis a V-shaped access opening for the livestock's head, and a catch position, in which they extend substantially vertically so as to allow engaging behind the livestock's head, the boundary post (14) having in an area adjacent at least one of the beams an end portion (14b,14d), which follows a course diverging from the fodder opening concerned towards the beam (4,5) concerned. <IMAGE>
Patent EP-0959763-B1 (EP)
Inventor: TORRESIN GIUSEPPE
IPC: A61B5/091
Filed: 1997-01-13
Granted: 2003-04-09
Abstract: The spirometer has a low thermal capacity. A circuit supplies power to the spirometer in pulses to heat the spirometer to body temperature. The circuit senses the temperature of the spirometer between intervals. The circuit can also be used in a calorimeter to measure the heat exchange during chemical reactions using the palladium hydrogen. The heating and sensing functions are performed by a single element to result in a small pocket sized device. The portability of the device increases its usefulness.
Patent EP-0883726-B1 (EP)
Inventor: FISCHBACH STEFAN
IPC: E05F15/00
Filed: 1997-02-28
Granted: 1999-09-01
Abstract: A sliding door system is provided which has a support frame including vertical posts and a horizontal transom. An assembly supporting a sliding door wing is supported at the support frame and includes a running mechanism operable to carry the door wing disposed in a running mechanism housing. A drive motor assembly disposed in a drive motor assembly housing is operably connected to the running mechanism to move the door wing. The running mechanism housing and the drive motor assembly housing are disposed one behind the other in a direction transverse to the transom and door wing and are configured and dimensioned to form a parallelepiped with a vertical height fitting within a vertical height of the transom.
Patent EP-0896578-B1 (EP)
Inventor: CHEN PAUL
IPC: C07D401/14
Filed: 1997-03-12
Granted: 2008-02-27
Abstract: Disclosed are compounds of compounds of the formula: or the pharmaceutically acceptable nontoxic salts thereof wherein: X is oxygen, H2 or sulfur Y is hydrogen, or optionally substituted alkyl, alkenyl, (substituted)arylalkyl, aryl or heteroaryl, or a carbonyl group substituted with alkyl, cycloalkyl, aryl, or amino groups; W is alkyl, arylalkyl or heteroarylalkyl, where each aryl group is optionally substituted with up to two groups; or W is aryl, thienyl, pyridyl or heteroaryl, each of which is optionally substituted; and Z1, Z2, Z3, and Z4 independently represent nitrogen or C-R1 where R1 is hydrogen, halogen, hydroxy, amino, or phenyl or pyridyl optionally mono- or independently disubstituted with halogen, hydroxy, lower alkyl, or lower alkoxy, which compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs of agonists or inverse agonists for GABAa brain receptors. These compounds are useful in the diagnosis and treatment of anxiety, sleep, and seizure disorders, overdose with benzodiazepine drugs, and enhancement of memory.
Patent EP-0892929-B1 (EP)
Inventor: HARTRUMPF MATTHIAS
IPC: G01S17/875
Filed: 1997-04-10
Granted: 2002-11-13
Abstract: PCT No. PCT/EP97/01783 Sec. 371 Date Feb. 9, 1999 Sec. 102(e) Date Feb. 9, 1999 PCT Filed Apr. 10, 1997 PCT Pub. No. WO97/38327 PCT Pub. Date Oct. 16, 1997A device is disclosed for measuring the co-ordinates of at least one retroreflector applied on an object. The light emitted by a lighting unit reaches the at least one retroreflector through a beam splitter, the light reflected from the retroreflector towards the beam splitter is separated from the path of the lighting beam, and said light falls on a detector unit by means of which the position of incidence of the detected light spot can be determined. The light from the lighting unit forms a beam which lights on the surface of the object a larger surface area than the surface area of the at least one retroreflector applied thereon. The detector unit is located in a place where the position and/or shape of the detected light spot change with the position of the retroreflector.
Patent EP-0891193-B1 (EP)
Inventor: BIERING WOLFGANG
IPC: A61L15/42
Filed: 1997-04-02
Granted: 2003-08-20
Abstract: The invention relates to a hemostatic sponge based on collagen and an activator or proactivator of blood coagulation homogeneously distributed therein, which is dried and contains a water content of at least 2%, preferably in the range of 2 to 25%, more preferred 10 to 20%, and a method for producing this sponge.
Patent EP-1009528-B1 (EP)
Inventor: CHEVALIER PHILIPPE
IPC: B02C15/04
Filed: 1997-04-15
Granted: 2002-07-03
Abstract: A grinder constituted by a ring (10) having a horizontal axis, a mechanism for driving the ring in rotation about its axis, at least one roller (16) the axis of which is parallel to that of the ring and which is placed inside the latter so as to be able to travel over its internal surface and elastic member (30) for pressing the roller against the ring, the roller being supported at its ends by two arms (22) mounted on the frame of the grinder so as to be able to pivot about an axis parallel to the axis of the ring.
Patent EP-0891213-B1 (EP)
Inventor: BONKHOFF KARIN
IPC: C02F1/26
Filed: 1997-04-01
Granted: 2001-08-29
Abstract: L'invention concerne l'extraction de composés organiques contenus dans des solutions aqueuses d'agents tensioactifs non ioniques. La solution aqueuse d'agents tensioactifs non ioniques (qui contient les composés organiques que l'on veut extraire) est intensivement mélangée à un liquide nonmiscible avec l'eau. La solution aqueuse qui contient les agents tensioactifs est ensuite séparée à nouveau du liquide nonmiscible avec l'eau. Le liquide nonmiscible avec l'eau contient alors les composés organiques et l'extraction est ainsi achevée. Le procédé est avantageusement mis en oeuvre au moyen d'un extracteur centrifuge.
Patent EP-0901405-B1 (EP)
Inventor: COELHO PHILIP H
IPC: A61M1/02
Filed: 1997-05-22
Granted: 2003-12-03
Abstract: A device for producing fibrinogen includes a platen having a surface configured for heat exchange with a container, which is adhered to the platen by device of a vacuum and heat exchange allowing both cooling and heating to occur along the boundary between the container and the platen. The platen is operatively coupled to a device of rocking the platen about a horizontal axis and the container allows scavenging of a cryoprecipitate fibrinogen from the blood product for subsequent utilization. A method for fabricating fibrinogen is also disclosed, including the steps of receiving blood product in a container having a heat transfer surface thereon, adhering a container to a heat transfer platen, rocking the container and coating the interior of the container with blood product, transferring heat and thereby altering the temperature of the platen, sensing the temperature of the platen and monitoring the platen temperature, and coupling the heat transfer to the temperature sensor and cycling the blood product through a phase change.
Patent EP-0898542-B1 (EP)
Inventor: STORCK MARKUS
IPC: B62K19/16
Filed: 1997-05-14
Granted: 2000-04-19
Abstract: A bicycle crank with a core comprised of a durofoam substance, a fiber-reinforced plastic coating encasing the core, a bottom bracket axle fitting arrangement foamed into the core accessible through the fiber-reinforced plastic coating, and a bottom bracket axle fitting arrangement foamed into the core accessible through the fiber-reinforced plastic coating.
Patent EP-0906311-B1 (EP)
Inventor: ASSMANN LUTZ
IPC: C07D401/12
Filed: 1997-05-30
Granted: 2003-04-23
Abstract: PCT No. PCT/EP97/02830 Sec. 371 Date Dec. 8, 1998 Sec. 102(e) Date Dec. 8, 1998 PCT Filed May 30, 1997 PCT Pub. No. WO97/47620 PCT Pub. Date Dec. 18, 1997The present invention concerns novel imidazol derivatives of the formula (I), in which R1, R2, R3 and A have the meanings given in the description, and the acid addition salts and metal salt complexes, several processes for the production of the novel substances and their use for combating undesirable micro-organisms in plant and material protection.
Patent EP-0912750-B1 (EP)
Inventor: LACEY COLIN NORMAN DOUGLAS
IPC: C12N15/82
Filed: 1997-07-03
Granted: 2003-05-21
Abstract: Pea seeds, produced from peas of the rug3rug3 genotype, substantially lacking plastidial phosphoglucomutase activity which have higher sucrose levels at the end of the vining period and may be vined over and extended period compared to conventional vining varieties are provided. Polynucleotides encoding pea plastidial phosphoglucomutase useful for altering the sucrose and starch content of plants, particularly peas, are also disclosed.
Patent EP-0923612-B1 (EP)
Inventor: CAMPBELL RICHARD E JR
IPC: C08F212/00
Filed: 1997-09-04
Granted: 2003-04-16
Abstract: Nouveaux types de copolymères de monomère aromatique d'alpha-oléfine/vinyle dont les spectres RMN au carbone 13 ont des signaux caractéristiques. En particulier, les copolymères d'éthylène/styrène décrits ont des crêtes dans les spectres considérés, qui apparaissent à l'intérieur du domaine de déplacement chimique compris entre 43,70 et 44,25 mg/l, de préférence entre 43,75 et 44,25 mg/l et entre 38,0 et 38,5 mg/l, ces crêtes équivalant au moins à trois fois le bruit de crête à crête. Les copolymères sont obtenus par polymérisation du mélange approprié de monomères, en présence d'un catalyseur comme le dichlorure de zirconium de (diméthylsilanediyle (2-méthyle-4-phénylindényle)) racémique. Les polymères décrits ont un module accru, du point de vue de la contrainte de traction/déformation due à la traction et des propriétés mécaniques dynamiques, à des niveaux de monomère aromatique de vinyle comparable.
Patent EP-0887914-B1 (EP)
Inventor: JESKE FRANK DIPL-ING
IPC: H02P6/14
Filed: 1994-11-21
Granted: 2002-07-24
Abstract: A voltage variable voltage (UC) is compared with another variable, which esp. is dependent on a variable to be controlled, e.g. a temp., in order with a specified comparison criterion, to produce a comparison signal (Udiff). The time difference (Td) between the beginning of the comparison signal (Udiff) and the time point of a second specified rotor setting (c.180 deg) following on the first specified rotor setting. Esp. of a second commutating time point, following on the first commutating time point, or a value (Td') near to this time difference, as well as the sense of this time difference, are determined. Based on this time difference (Td,Td') and their plus or minus sign, the switching 'on' and/or switching 'off' of the stator current (i1,i2) are controlled per unit time, according to at least one specified rule.
Patent EP-0908101-B1 (EP)
Inventor: PLAZAOLA IRIZAR ANTONIO
IPC: A23L7/157
Filed: 1998-02-09
Granted: 2001-10-17
Abstract: Including the use of wheat flower, powdered cacao, sugar, cornstarch, dextrose, soy lecithin, salt, ground cinnamon and yeast, in addition to water and a flavoring, and of performing the following processes: Mixing and kneading of the ingredients. Dividing the dough into portions and forming into balls. Fermentation of the balls of dough at 30oC, humidity 75% for 90 minutes. Cooking of the balls in an oven at 250o C for 40 minutes. Allowing the balls to rest for slow cooling. Dividing the product into pieces and drying by means of air heated to 280oC, reducing the moisture content to a maximum 8%. Cooling the product to the temperature of 50oC and final grinding to obtain a uniform-sized granulate. Applicable to the manufacture of a product easily prepared for serving by end consumers.
Patent EP-0975432-B1 (EP)
Inventor: STYNE JAMES J
IPC: B05D7/12
Filed: 1998-02-16
Granted: 2005-11-30
Abstract: An improved spraying device for mixing a first fluid with a second fluid prior to dispensing into the environment. The spraying device includes a spraying head connected to a cartridge bottle. A shroud covers the spraying head to cartridge bottle connection. The chemical remains in a closed system even after the cartridge bottle is attached to the spraying head. A unique gear and/or cam system is provided to open the flow path of the second fluid and provide a positive operation. Also, the orifice diameter of the second fluid flow path is predetermined.
Patent EP-0968056-B1 (EP)
Inventor: KRISTEN MARC OLIVER
IPC: C08F10/00
Filed: 1998-01-15
Granted: 2002-04-24
Abstract: A free-flowing solid which does not self-ignite, comprising:a) at least one support component,b) at least one chemical compound which per se is self-igniting,c) at least one inert liquid andd) further components.
Patent EP-0964889-B1 (EP)
Inventor: GEORGELLIS GEORGE BYRON
IPC: B01J8/24
Filed: 1998-03-04
Granted: 2004-07-14
Abstract: La présente invention concerne des mélanges de polypropylène spécialement adaptés à la fabrication de tissu et de fibre souple. Selon un mode de réalisation, ces mélanges comprennent un copolymère statistique d'éthylène-propylène présentant une teneur en éthylène de 1,0 % à 5,0 % en poids de ce copolymère, ce dernier représentant 40 % à 90 % en poids du mélange; et un bipolymère d'éthylène-propylène présentant une teneur en éthylène de 10 % à 30 % en poids de ce bipolymère, ce dernier représentant 10 % à 60 % du mélange. La présente invention concerne, en outre, un procédé hybride d'obtention de ces mélanges.
Patent EP-0966707-B1 (EP)
Inventor: TALBOT COLIN
IPC: G06F11/34
Filed: 1998-03-12
Granted: 2003-11-26
Abstract: A system for monitoring a process controlled by a user. A code generated by user input is paired with a code generated by the process in response to the user generated code. With reference to a master profile of code pairs, in the form of a variable file or look-up table, it is established whether the pair of codes are recognized as an appropriate pairing. In the case that the process generated code has not been recognized a false context state is established and, in the case in which a process generated code has been recognized, either a true context state is established if the recognized process generated code is deemed to have been produced in an appropriate context having regard to a correlation between the user generated input code and the corresponding code of the code master profile pair associated with the recognized process code, else a false context state is established. A raw activity record then stores an activity code specific to each recognized process generated code and the associated determined context state. The activity record may then be used as a basis for influencing the progress of the process.
Patent EP-0966861-B1 (EP)
Inventor: OLSSON FREDRIK
IPC: H04Q11/06
Filed: 1998-03-02
Granted: 2005-12-14
Abstract: Sequence integrity and frame integrity are preserved in switching wideband connections through a switch or a switch stage. The speech memory in a switch stage in the switch is extended to include storage positions that in number correspond to the number of time slots in two frames. These storage positions are arranged into two parts of the same size in the speech memory. Furthermore, there is provided a delay control unit in the time switch stage for generating delay information based on control information in the control memory of the switch stage and a determined part of the counter information from a time slot counter circuit. This delay information controls, for each time slot, to/from (depending on if the speech memory is arranged in an outgoing stage or an incoming stage) which one of the first and second parts of the speech memory that user data is switched.
Patent EP-0980441-B1 (EP)
Inventor: HELLERSTEIN MARC
IPC: C12Q1/02
Filed: 1998-05-08
Granted: 2007-04-11
Abstract: The present invention relates to a labeled deoxyribonucleic acid (DNA) molecule. In one aspect, the labeled DNA molecule is produced by contacting a cell or subject with a detectable amount of a stable isotope label which is incorporated into DNA via the de novo nucleotide synthesis pathway to produce the labeled DNA molecule.
Patent EP-1082028-B1 (EP)
Inventor: YANIV ZOHARA
IPC: A23K1/16
Filed: 1998-06-03
Granted: 2002-05-15
Abstract: The present invention relates to Matthiola incana seeds oil as an active ingredient in dietary supplements, mixtures and products for industrial use (useful for painting and lubrication) and pharmaceutical and cosmetic compositions useful for preventing and treating arteriosclerosis, coronary artery disease, chronic inflammatory disease, diabetes, cancerous tumor growth, prevention of blood vessels from closing following vascular surgery, improvement of inflammatory diseases, relieving symptoms of psoriasis, ensuring healthy skin condition and preventing skin wrinkles. The present invention further relates to a method for obtaining oil from Matthiola incana seeds comprising pressing of the plant seeds, collecting the resulting oil and purifying it, and also to a method for the preparation of mixtures containing Matthiola incana seeds oil comprising pressing Matthiola incana seeds, collecting the resulting oil, purifying it and mixing resulting oil into mixtures.
Patent EP-0976114-B1 (EP)
Title: Procede et systeme protege de carte a applications multiples
Inventor: EVERETT DAVID BARRINGTON
IPC: G06Q20/40
Filed: 1998-05-14
Granted: 2002-08-14
Abstract: L'invention porte sur un procédé et un système protégé de carte à applications multiples possédant une capacité de charge et de suppression grâce à une autorisation de certification et à un bureau de personnalisation. L'autorisation de certification maintient la sécurité du système en exigeant l'injection des cartes de circuit intégré avec sa clé publique, et un identificateur de carte permet d'identifier uniquement chaque carte en générant un bloc de données de personnalisation pour chaque carte et en signant avec sa clé privée toutes les applications de la carte à circuit intégré devant être chargées ou supprimées.