baber/WOPTO huggingface dataset:
Patent EP-1081133-B1 (EP)
Inventor: ONISHI TOMOYUKI
IPC: C07C271/16
Filed: 2000-08-31
Granted: 2004-03-31
Abstract: The invention relates to a method for industrially producing highly pure (2R, 3S)- or (2S, 3R)-N-carbamate-protected  beta -aminoepoxide (crystal) or (2R, 3S)- or (2S, 3R)-N-carbamate-protected  beta -aminoalcohol. The method for producing N-carbamate-protected  beta -aminoepoxide crystal, comprises the following steps (a) to (d):  (a) a step of dissolving (2R, 3S)- or (2S, 3R)-N-carbamate-protected  beta -aminoalcohol containing at least the diastereomer as an impurity in a solvent comprising at least one or more selected from aromatic hydrocarbon solvent, saturated hydrocarbon solvent, aqueous mixture solvent, acetone and 2-propanol, to remove insoluble matters; (b) a step of treating the (2R, 3S)- or (2S, 3R)-N-carbamate-protected  beta -aminoalcohol with a base, thereby converting the N-carbamate-protected  beta -aminoalcohol to (2R, 3S)- or (2S, 3R)-N-carbamate-protected  beta -aminoepoxide; (c) a step of treating the (2R, 3S)- or (2S, 3R)-N-carbamate-protected  beta -aminoepoxide containing at least the diastereomer as an impurity with an acid, thereby converting the diastereomer as an impurity to (4S, 5R) or (4R, 5S) oxazolidin-2-one derivative, and optionally separating and removing the resulting oxazolidin-2-one derivative in water or an aqueous mixture solvent; and (d) a step of crystallizing the (2R, 3S)- or (2S, 3R)-N-carbamate-protected  beta -aminoepoxide in a mixture solvent of water and water-miscible organic solvent.
Patent EP-1030233-B1 (EP)
Inventor: BOMMELAER CHRISTIAN
IPC: F16K31/68
Filed: 2000-02-11
Granted: 2004-04-21
Abstract: The mixer tap has a central membrane (109) displacing a common control rod (110). The valves (111,112) at the ends of the rod cooperate with valve seats (113,114). The rod runs in guides (115,116). The guide surfaces are at each end of the rod and are smaller than the section of the valves and/or operating rod.
Patent EP-1103215-B1 (EP)
Inventor: LEYMONERIE GUILLAUME
IPC: A47L13/16
Filed: 2000-11-29
Granted: 2007-12-12
Abstract: Cleaning cloth is made from woven or knitted fibres, some of which are looped to form raised zones relative to background - higher recuperation zones and lower storage zones. Recuperation zones have parallel lines running in either lengthwise or transverse directions, and different zones are in form of checkerboard squares with each storage zone (2) located between two recuperation zones. The cleaning cloth (1) is made from woven or knitted fibres, some of which are looped to form raised zones relative to the background - higher recuperation zones (3, 4) and lower storage zones (2). The recuperation zones have parallel lines (5, 6) running in either lengthwise (C) or transverse (T) directions, and the different zones are in the form of checkerboard squares with each storage zone (2) located between two recuperation zones which have their parallel lines in different directions. The squares have sides of 1 - 5 cm, the difference in height between recuperation and storage zones is 0.5 - 10 mm, and the density of the parallel lines is 3 - 7 per cm.
Patent EP-1150852-B1 (EP)
Inventor: NELLEN MARCEL JOHAN CHRISTIAAN
IPC: B60J7/05
Filed: 2000-02-03
Granted: 2003-06-11
Abstract: Cette structure de toit ouvrant, destinée à un véhicule présentant une ouverture (2) ménagée dans son toit fixe (1), comprend une partie fixe (3) à assujettir sur le toit, laquelle présente des glissières (6) situées de chaque côté de l'ouverture ménagée dans le toit. Un panneau (4) supporté par la partie fixe peut se régler entre une position fermée, dans laquelle il ferme l'ouverture du toit, et une position ouverte, dans laquelle il a été déplacé pour être mis dans une position située au-dessus du toit fixe. Le déplacement du toit ouvrant s'effectue à l'aide d'un mécanisme de fonctionnement (5) monté entre le panneau et les glissières, et comprenant une partie de support (9) qui soutient le panneau, ainsi qu'un élément coulissant (13) capable de se déplacer par coulissement le long des glissières.
Patent EP-1143970-B1 (EP)
Inventor: STRUCK ROBERT F
IPC: C07D405/12
Filed: 2000-01-21
Granted: 2010-07-21
Abstract: New pyridine compounds are provided along with their method of preparation. The compounds are useful as intermediates in preparing new anticancer agents. A few of the pyridine compounds are also useful for treating cancer.
Patent EP-1159861-B1 (EP)
Inventor: SCHIEBEL GUENTER
IPC: H05K13/04
Filed: 2000-03-01
Granted: 2004-11-17
Abstract: A freely positionable placement head ( 1 ) removes presented flip chips ( 6 ) from a wafer ( 5 ), the connection side of said chips being directed upward. The placement head has a turning device ( 9 ), in which, by the time they are placed onto a substrate ( 8 ) to be provided with placed components, the flip chips are turned in such a way that they can be placed with their connection side onto the substrate. This makes it possible to dispense with a complex turning device assigned to the wafer ( 5 ).
Patent EP-1178730-B1 (EP)
Inventor: PUJOL AMAT PERE
IPC: A23C9/123
Filed: 2000-05-05
Granted: 2005-03-23
Abstract: Use of lactic acid bacteria, e.g. <i>Lactobacillus casei</i> in the preparation of fermented milks for the treatment of temporarily depressed immunity levels in individuals subjected to physiological stress with a <i>Lactobacillus casei</i> content in excess of 1 x 10<5> c.f.u. per millilitre.
Patent EP-1179231-B1 (EP)
Inventor: BRAUN WARREN L
IPC: H04H20/67
Filed: 2000-05-22
Granted: 2005-11-02
Abstract: Interference effects between television transmitters for amplitude modulated or digital video and operating on a common allocated channel or frequency is avoided while discrimination is improved by synchronizing carrier signals for a plurality of transmitters. Booster transmitters for correcting coverage anomalies can operate of the same channel or frequency rather than requiring a different channel or frequency presently required in translators; making all allocable channels available for diverse broadcast programming. Discrimination between transmitters operating on the same channel or frequency but with potentially differing programming can be achieved with directional antennas. Synchronization of carrier signals is achieved by frequency multiplication of a tone relayed over a microwave transmission channel by an integral power of two using one or more serially connected full-wave rectifier stages and tuned filters.
Patent EP-1293076-B1 (EP)
Inventor: DESAIN PETRUS WILHELMUS MARIA
IPC: G06F17/30
Filed: 2000-06-19
Granted: 2004-10-06
Abstract: Method and server system for providing communication between a first user and at least one further user comprising the steps of sending a page comprising information to a first client computer for presentation to the first user, receiving a selection from the page from the first client computer, and sending information associated with the selection to at least one further client computer for presentation to a further user. In a further embodiment the method comprises the further steps of: sending a further page comprising further information associated with the selection to the at least one further client computer for presentation to the user, receiving a further selection from the further page, and sending information associated with the further selection to the first client computer for presentation to the first user.
Patent EP-1198254-B1 (EP)
Inventor: KRATZ FELIX
IPC: A61K49/00
Filed: 2000-06-07
Granted: 2007-08-15
Abstract: The invention relates to a carrier-drug conjugate comprising a carrier containing a polypeptide sequence having one or several cysteine radicals and a pharmacon containing a pharmaceutical and/or diagnostic active substance, a spacer molecule and a thiol binding group, whereby over 0.7 mol pharmacon per mol of cysteine radical is bound to the carrier by the thiol binding group. The invention also relates to a method for the production of said conjugate and to medicaments and diagnostic kits containing said conjugate.
Patent EP-1190079-B1 (EP)
Inventor: MCBRIDE KEVIN
IPC: C12N9/18
Filed: 2000-06-30
Granted: 2006-08-23
Abstract: DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from the luxI promoter ("lux box") or a functionally similar sequence are incorporated in a eukaryotic promoter. A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone (AHL) compound, interacts with the lux box, modulating the activity of the promoter.
Patent EP-1187928-B1 (EP)
Inventor: HUNT NICHOLAS
IPC: A61P35/00
Filed: 2000-06-30
Granted: 2007-05-23
Abstract: The invention relates to virus like particles, their preparation and their use in pharmaceutical screening and functional genomics. The particles are produced by co-expressing in cells a target molecule and a signal molecule wherein the signal and target molecules functionally operate in a non-covalent manner so as to incorporate or encapsulate said target molecules into said virus-like particles.
Patent EP-1200744-B1 (EP)
Inventor: REICHERT ARND
IPC: F15C1/16
Filed: 2000-07-27
Granted: 2005-04-06
Abstract: La présente invention concerne un dispositif permettant de réguler, en fonction des besoins, un flux d'air de refroidissement (1), notamment un flux d'air de refroidissement (1`) d'une turbine à gaz, avec des moyens nécessitant peu d'entretien. Ledit flux d'air de refroidissement s'écoule à travers un canal d'écoulement (2), un flux de fluide de régulation (30) étant introduit à travers le canal d'écoulement (2) dans ledit flux d'air de refroidissement (1), dans la zone du canal d'écoulement (2), avec une composante d'écoulement (9) qui est perpendiculaire à la direction d'écoulement (35) du flux d'air de refroidissement (1). La vitesse d'écoulement du flux d'air de refroidissement (1) peut être réglée en fonction de paramètres de régulation du flux de fluide de régulation (30) et/ou d'autres paramètres.
Patent EP-1228128-B1 (EP)
Inventor: KOCH DIETHER
IPC: C08K3/24
Filed: 2000-08-10
Granted: 2003-11-26
Abstract: The invention relates to a binding agent which contains resol, a base and water and that is characterised in that the binding agent system additionally contains at least one aluminium-containing oxyanion and at least one boron-containing oxyanion.
Patent EP-1340033-B1 (EP)
Inventor: ANDRE DOMINIQUE
IPC: F41A17/44
Filed: 2000-08-11
Granted: 2008-10-29
Abstract: The invention concerns a key-operated sleeve device for locking firearms. The inventive device operates with a key (4) enabling to lock a firearm. Said device consists of an element similar to a cartridge inserted solely in the firearm chamber and provided with a very efficient system for safe and non-aggressive locking of the firearm with a key. The inventive device is particularly designed for locking a firearm in the absence of its owner or without his knowledge.
Patent EP-1219025-B1 (EP)
Inventor: HOFMANN HEIKE
IPC: H03F1/32
Filed: 2000-09-14
Granted: 2005-11-16
Abstract: A predistorter is connected upstream of a high-frequency amplifier to be linearized. A predistortion factor is adaptively modified in the predistorter in such a way as to compensate non-linearities of the amplifier as well as possible. The quotient of the output signal of the high-frequency amplifier and the input signal of the predistorter is produced first. An average amplification is then determined based on the signal quotient. A correction term is produced for the predistortion factor, this correction term being dependent on the extent of the deviation of the average amplification from a set value. The predistortion factor is adaptively modified in such a way as to minimize the correction term.
Patent EP-1226413-B1 (EP)
Inventor: HERB GLENN T
IPC: G06F17/15
Filed: 2000-10-24
Granted: 2006-09-06
Abstract: The ultrasonic thermometer system of the present invention includes a rod or probe of high temperature, grain-stabilized material that has a magnetostrictive or piezoelectric transducer bonded to one end. The transducer is excited by a transducer driver, creating short, periodic, ultrasonic pulses that travel down the length of the rod in a "pulse-echo" fashion. Along the length of the rod, circumferential grooves are cut which reflect some of the ultrasonic energy back to the transducer thus creating a reflected or echo signal. Two such reflected signals from two adjacent grooves, or a signal from one groove and a signal from the end of the rod, establish a temperature zone. This is the zone of interest to the user, which would be inserted into the user's process that needs to have the temperature monitored. As the temperature of the zone changes, the transition time of the ultrasonic pulse through the zone also changes, thus providing a measurable indication of average temperature and changes in average temperature of the temperature zone. There may be one or multiple temperature zones on one rod. A processor is also provided to correlate the signals generated by the transducer and reflected by the grooves with template signals to generate a temperature reading.
Patent EP-1230446-B1 (EP)
Inventor: FAUCHER JEROME R
IPC: C25D17/00
Filed: 2000-10-16
Granted: 2005-05-04
Abstract: A conveyorized electroplating device having an anode positioned proximate to a plurality of absorptive applicator assemblies that apply a plating solution to a substrate and a conveyor device that grips the substrate thereby isolating the electrical contact from the plating solution. The conveyorized electroplating device has a fluid bed assembly with a manifold and an anode, a conveyor device adjacent to the fluid bed assembly, and a plurality of absorptive applicator assemblies, wherein the plurality of absorptive applicator assemblies are adjacent and in close proximity to the anode and in fluid communication with the fluid bed assembly. The conveyor device isolates the electrical contacts from the plating solution and is able to handle various sizes and thicknesses of substrates. The conveyor device of the present invention comprises a drive assembly and a gripper assembly connected thereto, wherein the gripper assembly has a non-metallic housing, a metallic member slideably mounted within a cavity defined by the non-metallic housing, an arm pivotably mounted to the housing and forming a passageway, and a seal mounted adjacent to the arm.
Patent EP-1233783-B1 (EP)
Title: Hbv/hcv virus-like particle
Inventor: SELBY MARK
IPC: C07K19/00
Filed: 2000-11-22
Granted: 2005-03-09
Abstract: Chimeric antigens derived from hepatitis B virus (HBV) and hepatitis C virus (HCV) are described which form virus-like particles when co-expressed with an excess of hepatitis B virus surface antigen (HBsAg). The chimeric antigens are fusion proteins containing an immunogenic peptide derived from an HCV protein coupled to the amino terminus of HBsAg. Also described are nucleic acid constructs and vectors for transfection of cells and expression of the chimeric antigens. The invention further provides methods for producing HBV/HCV virus-like particles containing the chimeric antigens, cell lines for producing the virus-like particles, combination vaccines containing the virus-like particles, and DNA vaccines that express the virus-like particles.
Patent EP-1120196-B1 (EP)
Inventor: TAKAHASHI TSUTOMU
IPC: B24D3/06
Filed: 2001-01-16
Granted: 2005-06-01
Abstract: The invention relates to an electroplated grinding wheel having abrasive grain layer parts in which plural abrasive grains are fixed with the metal bonding phase. The abrasive grain layer part has a high abrasive grains concentration at a center part of said abrasive grain layer part and a low abrasive grain concentration at a surrounding area of said abrasive grain layer part. <IMAGE>
Patent EP-1134449-B1 (EP)
Inventor: FRIEDL REINHARD
IPC: F16D55/40
Filed: 2001-03-07
Granted: 2005-06-08
Abstract: The device has gripper rings (4) and spring washers (6) arranged on bolts (3), as well as a support ring (5) and a fixing ring (6). The support ring is fixed axially to the casing (1) of the brake by the fixing ring and can rotate. The bolts slide axially in the piston (2) of the brake, so that they act as a tangential carrier for the support ring (5).
Patent EP-1258435-B1 (EP)
Inventor: KRISTENSSON INGVAR
IPC: A47F1/06
Filed: 2001-05-16
Granted: 2006-03-15
Abstract: A method and device (1) for automatically dispensing straws (2), whereby a cartridge belt (11) of straws (2) - defined by a flexible belt (12) narrower than the length of the straws (2) and having a succession of transverse tubular seats (13) equally spaced along the flexible (12) and housing respective straws (2) in axially sliding manner - is fed in steps along a path (P) extending through a withdrawal station (18) where a feed device (15) and an extracting device (19) respectively provide, each time they are activated, for feeding the flexible belt (12) one step forward and sliding a straw (2a) partly along the respective tubular seat (13) into a withdrawal position. <IMAGE>   <IMAGE>
Patent EP-1118751-B1 (EP)
Inventor: SALVAT OLIVIER
IPC: F02D43/00
Filed: 2001-01-18
Granted: 2005-03-23
Abstract: The regeneration circuit for a motor vehicle exhaust gas filter has a control circuit (17) for the engine management system, to trigger a filter regeneration phase and to trigger a fuel injection phase for the multiple engine injectors. The control circuit closes the exhaust gas recycling circuit when the filter regeneration phase is in operation to allow control of the composition of the gas entering the particulate filter (17) as a function of engine isocouple. The recycling circuit can be opened and closed by a solenoid valve (4).
Patent EP-1167679-B1 (EP)
Inventor: GROSSE GERARD
IPC: E06B9/11
Filed: 2001-06-14
Granted: 2005-04-27
Abstract: The roller shutter component comprises at least two planks (1,2) joined by a connecting component (3). One of the planks has a reception groove (11) for a lateral part (4) of the connecting component. The groove is delimited on one of its sides by a demountable wall (21).
Patent EP-1182163-B1 (EP)
Inventor: MATEO MUR FRANCISCO
IPC: B66B5/04
Filed: 2001-08-06
Granted: 2003-12-17
Abstract: Limiting device for elevators, that is, it is related with a device which does not permit a threshold speed to be surpassed, in such a manner that once surpassed it provokes the halting of the elevetor by means of the actuation of a "safety" which causes it to become wedged. The speed limiter object of the invention can work in both the upward and downward directions and is mounted on the elevator car.
Patent EP-1257228-B1 (EP)
Title: Mixing capsule
Inventor: PEUKER MARC
IPC: A61C5/66
Filed: 2001-02-15
Granted: 2006-06-28
Abstract: The invention relates to a mixing capsule, especially for producing dental materials. The inventive capsule is provided with a cartridge which is closed on one end thereof by means of a piston. A hemispherical cavity is configured in the piston. Said cavity forms an additional chamber and is closed in relation to the main chamber of the cartridge by means of a separating device. A body that is present in the main chamber in the initial state serves for supporting the mixing process and for chopping through the separating device at the beginning of the mixing process in such a way that the main chamber and the additional chamber form a coherent mixing chamber. The body enters the hemispherical additional chamber and acts as a displacing body at the end of the output process. The mixing capsule is provided with a coding.
Patent EP-1272219-B1 (EP)
Inventor: BONDJERS GOERAN
IPC: A61K31/505
Filed: 2001-03-27
Granted: 2006-12-13
Abstract: La présente invention concerne des formulations pharmaceutiques comprenant un bétabloquant et un hypocholestérolémiant mélangés à un adjuvant pharmaceutiquement tolérable, un diluant ou un excipient. L'invention concerne également un kit de pièces, un procédé de traitement et d'utilisation de ces formulations pour prévenir ou traiter l'athérosclérose, l'hypercholestérolémie et l'hyperlipoprotéinémie.
Patent EP-1250161-B1 (EP)
Inventor: KATSARAVA RAMAZ
IPC: A01N63/40
Filed: 2001-01-11
Granted: 2005-12-21
Abstract: Methods and devices for sanitation using bacteriophage are disclosed. According to one embodiment of the present invention, a method for sanitation using at least one bacteriophage includes the steps of (1) storing the at least one bacteriophage in a container; and (2) applying the at least one bacteriophage to a surface to be sanitized with a dispersing mechanism. According to another embodiment of the present invention, a sanitation device that dispenses at least one bacteriophage includes a container, at least one bacteriophage stored in the container, and a dispersing mechanism that disperses the at least one bacteriophage from the container. <IMAGE>
Patent EP-1281239-B1 (EP)
Inventor: FREDRIKSSON JESPER
IPC: H03K5/19
Filed: 2001-04-04
Granted: 2011-07-27
Abstract: The invention is generally directed towards monitoring of a signal (m), such as a clock signal or a data signal, by sampling the signal to obtain a discrete sample representation of the signal and analyzing the sample representation. The idea according to the invention is to slide a sample window (sw) over the sampled signal and determine whether the samples currently within the window include a valid transition sequence. in the general case, the existence of a valid signal is confirmed as long as a valid transition sequence is present in at least one of a predetermined number of consecutive sample windows. in order to reduce the need for oversampling in high-frequency applications, the invention furthermore proposes a multi-phase sampling technique according to which a number of phase-shifted sample clocks (s1 to sn) are generated for the purpose of sampling the signal to be monitored. Higher-frequency oversampling is thus replaced by a higher resolution in the time domain.
Patent EP-1299484-B1 (EP)
Inventor: TYE ANTHONY
IPC: C09D7/47
Filed: 2001-04-11
Granted: 2004-06-23
Abstract: The present invention provides a coating composition comprising no more than 2.00 % by weight nonvolatile of Si-containing compounds, based on the total nonvolatile weight of the coating composition, and from 0.25 to no more than 5.0 % by weight of a volatile linear siloxane of a particular formula. The invention also provides a method of providing a cured coating composition having an improved distinctness of image as well as a method of coating a substrate. The compositions of the invention have improved resistance to visual defects believed to be caused by surface contamination, such as "fisheyes" or "cratering" and "telegraphing".
Patent EP-1296740-B1 (EP)
Inventor: PETTIS RONALD J
IPC: A61M37/00
Filed: 2001-06-29
Granted: 2007-11-14
Abstract: The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gange needles, especially microneedles, placed in the intradermal space to deliver the substance to the intrademial space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient. Delivery devices which place the needle outlet at an appropriate depth in the intradermal space and control the volume and rate of fluid delivery provide accurate delivery of the substance to the desired location without leakage.