baber/WOPTO huggingface dataset:
Patent DK-0497997-T3 (DK)
Inventor: GLUECK REINHARD DR
IPC: A61K47/48
Filed: 1991-02-02
Granted: 1995-11-27
Abstract: The phospholipid bi-layer vesicle contains at least one pharmaceutically active drug and comprises cell-specific markers on the membrane which have at least 90 % biological activity when measured according to Luescher & Glueck, Antiviral Research 14, 39-50. In the membrane, the cholesterol content is preferably less than 2% by weight, the detergent content preferably less than 1 ppb. The vesicle diameter preferably is about 80 nm. The phospholipid in the membrane may comprise 70 to 95 % by weight of phosphatidylcholine and preferably 10 to 20 % by weight of phosphatidylethanolamine; preferably 6 to 8 % by weight of a crosslinker, preferably of a sulfosuccinimidyl derivate, and at least one cell-specific fusion peptide are linked to the membrane. The vesicles are used for the preparation of pharmaceuticals against AIDS and carcinomas. The process for the preparation of phospholipid bi-layer vesicles comprises hemagglutinin as a cell-specific marker with at least one fusion peptide. The hemagglutinin is separated from a virus strain by means of a non-ionic detergent, preferably octaethylene glycol monododecyl ether. It is removed by repeatedly treating the solution with altogether about 1.5 g polystyrene beaded microcarriers per 100 mg detergent.
Patent DK-0451792-T3 (DK)
Inventor: WOHLLEBEN WOLFGANG DR
IPC: C12N15/76
Filed: 1991-04-09
Granted: 1997-09-15
Abstract: The kil-kor system from the plasmid pIJ101 can be used for regulated gene expression in streptomyces. For this, the korA protein is either inactivated or eliminated in order to "acquire" a particular gene. <IMAGE>
Patent DK-0439209-T3 (DK)
Inventor: HAUBACH CLAUS CARL FERDINAND
IPC: B65D33/10
Filed: 1991-01-11
Granted: 1995-09-11
Abstract: Paper bag with integral carrying device consisting of two main panels (2,1), two side panels (3,4), a bottom panel and a top panel, whereby the integral carrying device is formed by folding over extensions of said main panels and by punching a carrying hole (18) in said folded-over extensions of said main panels. <IMAGE>
Patent DK-0479573-T3 (DK)
Inventor: BLUM JOHN L
IPC: A61F5/445
Filed: 1991-10-02
Granted: 1996-02-05
Abstract: The insert (D) is received within the coupling ring (10) of the faceplate of a two piece ostomy device. The coupling ring has an axially extending rib and a rigid sealing flange defined in part by a radially inwardly extending surface (40). The insert includes a convex annular body (46) with an arcuate relatively non-deformable portion and a deformable circumferential portion (48). The deformable portion has an outer edge with a circumference which is normally slightly larger than the inner circumference of the sealing flange. The circumference of the deformable portion is temporarily reduced as the insert passes through the ring. Once the insert is situated under the flange surface, the circumference returns to its normal dimension and the insert is securely seated. <IMAGE>
Patent DK-0547151-T3 (DK)
Inventor: LARDY HENRY A
IPC: A61P1/00
Filed: 1991-08-28
Granted: 2003-03-17
Abstract: A method for controlling weight gain or promoting weight loss which includes the step of treating a subject with an effective weight gain controlling or weight loss promoting amount of a substituted (Delta)5-Androstene which is biologically effective for controlling weight gain or promoting weight loss and biologically ineffective for promoting the synthesis of sex hormones. Steroids believed to provide the desired weight control/weight loss characteristics include: (Delta)5-Androstene-3(beta),7(alpha)-diol-17-one (Delta)5-Androstene-3(beta)-ol-7,17-dione (Delta)5-Androstene-3(beta),7(alpha),17-triol (Delta)5-Androstene-3(beta),17(beta)-diol-7-one and various derivatives thereof.
Patent DK-0552251-T3 (DK)
Inventor: ELLIS ERNEST W
IPC: B41M3/14
Filed: 1991-09-25
Granted: 2001-03-19
Abstract: A unique method/system for simultaneously creating and transferring a contrasting pattern of intelligence on and from a composite ablation-transfer imaging medium to a receptor element in contiguous registration therewith is improvedly radiation sensitive and versatile, is kinetically rapid and not dependent on a sensitized ablative topcoat, and is well adopted for such applications as, e.g., color proofing and printing, the security coding of various documents and the production of masks for the graphic arts and printed circuit industries; the composite ablation-transfer imaging medium, per se, comprises a support substrate (i), at least one intermediate "dynamic release layer" (ii) essentially coextensive therewith and an imaging radiation-ablative carrier topcoat (iii) also essentially coextensive therewith, said imaging radiation-ablative carrier topcoat (iii) including an imaging amount of a constrast imaging material contained therein, and said at least one dynamic release layer (ii) absorbing such imaging radiation at a rate sufficient to effect the imagewise ablation mass transfer of at least said carrier topcoat (iii).
Patent DK-0503244-T3 (DK)
Inventor: BLAESS JUERGEN
IPC: F16L19/02
Filed: 1992-01-23
Granted: 1996-04-15
Abstract: An assembly for connecting a fitting (2) to a pipe (16) contains a union nut (18) assigned to the pipe, the internal thread (28) of which engages in an external thread (10) of the fitting (2). The union nut (18) is in engagement with an insert (12) which can be connected to the pipe (16). The intention is to further develop the connection assembly with a low outlay on construction in such a way that the fitting (2) can be connected with as few components as possible to the pipe (16) by means of a standardised union nut (18) via the non-standard external thread (10) of the fitting. It is proposed to arrange between the internal thread (28), the union nut (18) and the external thread (10) a threaded ring (30), the external thread of which is designed to correspond to the internal thread (28) of the union nut as a standardised thread, in particular in accordance with DIN 2950. After the tightening of the union nut (18), the axial end face (34) of the threaded ring (30) is set back by a predetermined distance relative to the front face (24) of the housing (4). <IMAGE>
Patent DK-0505055-T3 (DK)
Inventor: HERRINGTON FOX JOHN
IPC: A44B19/16
Filed: 1992-03-05
Granted: 1995-06-12
Abstract: A method of making an end stop for a slider of a fastener structure for a thermoplastic bag. The fastener structure comprises a pair of flexible plastic strips adapted to be connected to the walls of the bag (B) and having reclosable interlocking male and female profile elements (16,17) on the respective strips (14,15) and a slider (10) straddling the strips for opening and closing them. The method comprises clamping together a pair of the flexible plastic strips between clamps (40,41) at a seal area in the region intended to form an end of the strips, the clamps (40a,40b) having pockets (41a,41b) therein adjacent the profile elements at the seal area. The profile elements are severed and heated at the seal area with a heated knife (45) to transform the severed ends of the profile elements into molten material; the molten material is pressed into the pockets in the clamps (40,41) with the heated knife (45) thereby increasing the thickness of an area of the strips adjacent the seal area to provide a protruding end stop for preventing movement of the slider past the ends of the bag (30). <IMAGE>
Patent DK-0528557-T3 (DK)
Inventor: FAUTEUX DENIS
IPC: H01M4/66
Filed: 1992-07-29
Granted: 2000-05-22
Abstract: A carbon/polymer composite electrode comprises substantially amorphous carbon entrapped in a polymeric matrix, wherein the matrix further entraps an interpenetrating ionically conducting liquid having an alkali metal salt dissolved therein. Such an electrode may be used as the anode in an electrochemical cell, or battery, which also comprises a polymeric electrolyte and a cathode. The cathode may be a vanadium oxide composition containing intercalated lithium ions or LiCoO2.
Patent DK-0664708-T3 (DK)
Inventor: SUNKARA SAI P
IPC: C07D473/02
Filed: 1993-03-15
Granted: 1998-11-02
Abstract: The present invention relates to a method of treating a patient suffering from a neoplastic disease state comprising administering to said patient an effective antineoplastic amount of a 2'-halomethylidene derivative in conjunctive therapy with an effective antineoplastic amount of a S phase or M-phase specific agent.
Patent DK-0644746-T3 (DK)
Inventor: HEIBER WERNER E
IPC: A61K9/70
Filed: 1993-05-03
Granted: 1999-12-20
Abstract: A transdermal/transmucosal drug delivery system utilizes glycerin to moderate the initial burst effect of transdermal drug delivery and also maintain the delivery to the derma/mucosa at a relatively sustained rate over the duration of the application to either an application or afflicted situs. The drug composition contains an effective amount of a percutaneously absorbable drug and an amount of glycerin which is effective to moderate and maintain the transdermal delivery of the drug. The system also contains means for maintaining the drug composition in a drug transferring relationship with the derma/mucosa. When applied to an afflicted situs the composition is preferably a gel, cream, lotion or ointment. When applied to an application situs the compositions are contained within a device such as a matrix or liquid reservoir patch which is held to the application site by means of the adhesive. The drug composition may contain glycerin in amounts of between about 0.1 to 50 % by volume.
Patent DK-0686036-T3 (DK)
Inventor: SCHOLZ PETER
IPC: A61K31/557
Filed: 1993-08-09
Granted: 1997-10-13
Abstract: PCT No. PCT/DE93/00722 Sec. 371 Date Jun. 9, 1995 Sec. 102(e) Date Jun. 9, 1995 PCT Filed Aug. 9, 1993 PCT Pub. No. WO94/03175 PCT Pub. Date Feb. 17, 1994The invention relates to the use of prostane derivatives general formula I    <IMAGE>  Formula I  in which X1 is a -CH2-CH2- or trans -CH=CH-, X2 is a straight-chain or branched, saturated alkylene group with 1 to 6 carbon atoms, X3 is a -CH2-, X4 is a -CH2-, X5 is a -C 3BOND C-R2; R1 is a hydrogen atom, an alkyl group with 1 to 6 carbon atoms, a cycloalkyl group with 5 or 6 carbon atoms, or a phenyl group, R2 is a straight-chain or branched-chain, saturated or unsaturated alkyl group with 1 to 6 carbon atoms, R3 is a hydrogen atom or an acyl radical with 1 to 4 carbon atoms, and R4 is an -H; in which the -O-R3 group is in  alpha - or  beta -position, and their salts with physiologically compatible bases, if R1 indicates a hydrogen atom, for the production of a pharmaceutical agent for the treatment of chronic polyarthritis.
Patent DK-0643134-T3 (DK)
Inventor: PREVOTS FABIEN
IPC: C12N1/21
Filed: 1994-08-05
Granted: 2002-03-18
Abstract: The subject of the invention is a DNA sequence of about 1.9 kb comprising at least one mechanism for resistance to phages, obtained from the 3.3 kb HindIII-HindIII DNA sequence, contained in the Lactococcus lactis ssp lactis strain deposited at C.N.C.M under No.1-945, by the PCR method.
Patent DK-0695349-T3 (DK)
Inventor: KOFOD LENE VENKE
IPC: A23L29/00
Filed: 1994-03-02
Granted: 2004-06-01
Abstract: An enzyme exhibiting xylanase activity, which enzyme is immunologically reactive with an antibody raised against a purified xylanase derived from Aspergillus aculeatus, CBS 101.43. The enzyme may be used for degrading plant cell wall components e.g. in the preparation of feed, in baking, in the paper and pulp industry and in connection with separation of wheat into starch and gluten.
Patent DK-0696278-T3 (DK)
Inventor: JAMES DONALD RICHARD
IPC: A01P13/00
Filed: 1994-04-28
Granted: 1999-04-26
Abstract: Substituted N-benzotriazoles of the general formula   <IMAGE>   exhibit herbicidal activity. Herbicidal compositions and related methods of using the substituted N-benzotriazoles are also disclosed.
Patent DK-0725198-T3 (DK)
Inventor: ZEUS CHRISTIAN
IPC: E05B63/20
Filed: 1995-11-04
Granted: 1998-03-30
Abstract: The lock bolt (80) operated by a closure element (81) penetrates the lock plate (20). At least two longitudinally movable slide rods (30, 31) joined by a connecting element (40) have locking elements (33) fitting into corresponding holes (35). The slide rods are movable against restoring force by means of a handle (61) rotatingly mounted in a lock-nut (60) and are locked in this opened position. The slide rods are released by directly operating the locking elements in the lock plate`s longitudinal direction (L). Closing the door (T) exerts force on the locking elements, acting parallel with the slide rods.
Patent DK-0734261-T3 (DK)
Inventor: CUPPS THOMAS LEE
IPC: A61P27/02
Filed: 1994-12-15
Granted: 2001-09-03
Abstract: The subject invention involves methods of treating nasal congestion comprising administration, to a human or lower animal in need of such treatment of a safe and effective amount of a compound having the following structure:   <IMAGE>   wherein: (a) R is unsubstituted C1-C3 alkanyl or alkenyl; and (b) R' is selected from hydrogen; unsubstituted C1-C3 alkanyl or alkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thiol; cyano; and halo. The subject invention also involves the use of such compounds for preventing or treating other respiratory, ocular and/or gastrointestinal disorders. The subject invention also involves novel compounds having the above structure wherein R' is hydrogen or fluoro or cyano.
Patent DK-0760010-T3 (DK)
Inventor: PLEVY SCOTT E
IPC: C12Q1/6858
Filed: 1995-05-17
Granted: 2002-02-25
Abstract: A novel association between certain tumor necrosis factor microsatellite alleles and Crohn's disease has been discovered. In accordance with the present invention, there is provided methods for screening for Crohn's disease comprising detecting the presence or absence of nucleic acid of a subject encoding TNF microsatellite alleles associated with Crohn's disease, wherein the presence of nucleic acid encoding three or more of the alleles is indicative of Crohn's disease. Kits useful for screening for Crohn's disease are also provided which comprise nucleic acid encoding TNF microsatellite alleles associated with Crohn's disease.
Patent DK-0835386-T3 (DK)
Inventor: KIRK IAN ALISTAIR
IPC: F16B7/14
Filed: 1995-08-10
Granted: 2000-06-26
Abstract: PCT No. PCT/GB95/01890 Sec. 371 Date Feb. 11, 1997 Sec. 102(e) Date Feb. 11, 1997 PCT Filed Aug. 10, 1995 PCT Pub. No. WO96/05439 PCT Pub. Date Feb. 22, 1996A gripping device (10) is described which has an inner member (14) and an outer member (12). The inner member has a split (20) which define a first end (6) and a second end (8). A selectively operable device (18) is also included to keep the first and second ends (6, 8) apart to permit the device (10) to be placed around an object (30) and to permit the first and second ends (6, 8) to move towards each other so that the inner member (14) grips the object (30). At least part of an outer face (26) of the inner member (14) interfits with at least a part of an inner face (22) of the outer member (12) in a manner such that when a load is applied to the outer member (12), the inner face (22) of the outer member (12) acts upon the inner member (14) to cause compression of the inner member (14) thereby increasing the grip of the inner member (14) on the object (30). The device (10) is then locked in position on the object (30) and when the load is removed the action of the outer member (12) on the inner member (14) is reduced thereby decreasing the grip of the inner member (14) on the object (30) and unlocking the device (10) from the object (30).
Patent DK-0748632-T3 (DK)
Inventor: FAGES JACQUES
IPC: A61L2/00
Filed: 1996-06-03
Granted: 2002-07-15
Abstract: Antiviral prophylaxis of collagenic tissue, partic. human or animal bone tissue intended for use as biomaterials, comprises eliminating viral contamination by :(i) placing the tissue in a stream of carbon dioxide in the supercritical state; (ii) treating with a hydrogen peroxide soln.; (iii) treating with sodium hydroxide soln.; and (iv) treating with an ethanol soln. Supercritical carbon dioxide is used in an amt. of 100-500 (pref. 300)/g of collagenic tissue at 1-5 (pref. 2.5) x 10<7> Pa at 40-55 (pref. 50) degrees C. Hydrogen peroxide is used in an amt. of at least 1 (pref. 35) wt.% at 30-50 (pref. 40) degrees C. Sodium hydroxide is used in an amt. of 3-15 (pref. 4) wt.%, following which the tissue is rinsed with water and immersed in a neutralising soln. During the final stage of treatment, tissue is immersed in > 90 (pref. 95) vol.% ethanol and then in > 95 (pref. 100) vol.% ethanol
Patent DK-0862623-T3 (DK)
Inventor: GHANI MAHMOOD M
IPC: A23L29/00
Filed: 1996-10-04
Granted: 2004-10-18
Abstract: A microgranular enzyme composition having an average particle size of from about 20 to 400 microns is disclosed. The microgranular composition has low dusting, high blendability and quick dispersion characteristics particularly beneficial to the food and/or feed industries. Also disclosed are methods for making such enzyme-containing microgranules.
Patent DK-0791689-T3 (DK)
Inventor: BARTH GUENTER DR
IPC: E01C5/00
Filed: 1997-02-14
Granted: 2003-04-14
Abstract: There is provided an artificial stone for strengthening traffic surfaces in the open, in which the stone, in order to provide wide grooves between adjacently laid stones, is provided on its edge surfaces with integrally formed, completely identical spacer elements, the contacting free end surfaces of the spacer elements having, adjacent one another, a tooth and a recessed contact surface for the tooth of the adjacently laid stone; the tooth-recess sequence, in one peripheral direction of the stone, being the same for all spacer elements; the effective length of the individual edge surfaces of a stone, parallel to the laying plane, being the same as, or a whole-number multiple of, a smallest effective length; each edge surface segment which has the smallest effective length being provided with a spacer element; and the central axes of all spacer elements lying in the middle of the corresponding edge surface segment. The contact surface is formed as a tooth recess corresponding to the size of the tooth and enclosing the latter on both sides in the direction parallel to the laying plane and to the corresponding edge surface. The flanks of thee tooth and of the tooth recess enclose an angle of at least 90 degrees, and the bisector of the angle is essentially parallel to a perpendicular drawn to the corresponding edge surface.
Patent DK-0886910-T3 (DK)
Inventor: LAMB KARL J
IPC: H02K49/04
Filed: 1997-03-13
Granted: 2002-05-13
Abstract: A magnetic coupling device has an electroconductive rotor presenting a band of electroconductive material and has a magnet rotor with permanent magnets which are slide-mounted to move radially outward responsive to centrifugal force in opposition to a spring bias. When the magnet rotor is stationary the magnets are radially inward of the orbit of the electroconductive band, and when the magnets have moved outwardly when the magnet rotor is rotating, the magnets are spaced by an air gap from the electroconductive band so that eddy currents are induced in the band resulting in coupling of the rotors. The electroconductive rotor preferably has two such bands positioned on opposite sides of the magnet rotor. The rotors may have sheaves mounted thereon.
Patent DK-0914818-T3 (DK)
Inventor: HAYAKAWA EIJI
IPC: A61K47/26
Filed: 1997-06-12
Granted: 2005-07-04
Abstract: A tablet comprising sugar alcohol or saccaride having an average particle diameter of not more than 30  mu m, an active ingredient, and a disintegrant. It is an intraorally rapidly disintegrable tablet which does not require a special pharmaceutical manufacturing technology and can be simply and easily produced by a normal equipment.
Patent DK-0909998-T3 (DK)
Inventor: KOERFGEN HARALD
IPC: G05D23/13
Filed: 1998-09-26
Granted: 2004-04-05
Abstract: The arrangement (1) has at least one water inlet opening, a water outlet opening (4) and a regulation and/or blocking element with at least one electrical control device (81) for controlling the water outlet or throughput. The control device has an associated speaker independent or dependent speech recognition system (9) for contactless operation which responds to at least two spoken commands enabling water outlet and blocking with first and second phonetic commands respectively
Patent DK-1140613-T3 (DK)
Inventor: SIMON WERNER
IPC: F16G15/08
Filed: 1998-12-22
Granted: 2003-01-27
Abstract: The invention relates to a connector (15) which consists of an anchor connection component (16) and a chain connection component (17). Said anchor connection component (16) is provided at its one end with a location fork (21) for the anchor. Said chain connection component (17) is provided at its one end with a fork part (41) for accommodating a chain link. One screw bolt (25, 46) each penetrates the limbs (23, 24) of the location fork and the limbs (44, 45) of the fork part (41). Said screw bolt is fixed with its head in the one limb and with its screw shaft (28, 47) in the other limb and is secured by an attachment screw (48) if required. The anchor connection component (16) and the chain connection component (17) are linked with one another via a ball-and-socket joint (19). One component is provided with a ball (38) and the other component with a socket (34) with an opening (37) leading to the location fork (21). The aim of the invention is to facilitate wet-cleaning the ball location room (22) from impurities. To this end, the socket (34) is provided with a hollow sphere section for holding the ball (38) if a tensile load is applied. Said hollow section faces away from the location fork (21). The ball is provided with a front face (39) which faces the location fork (21) and recedes behind the spherical shape. Said front face together with a cylindrical recess (29) which protrudes from the hollow sphere section and faces the location fork (21) forms a pump chamber.
Patent DK-1005964-T3 (DK)
Inventor: WILMS HEINRICH
IPC: B27M3/34
Filed: 1999-11-24
Granted: 2005-05-17
Abstract: The wooden panel for sterilising articles has a planar panel with sections (2) to absorb and kill bacteria at least in the area of its upper work surface (5) which is made of dried heart wood. The wood can be oak or larch. The dried heart wood has a moisture content of around zero.
Patent DK-1233799-T3 (DK)
Inventor: FRANKLIN-LEES DAVID
IPC: F16M13/02
Filed: 1999-11-19
Granted: 2006-05-22
Abstract: An interface device secures an instrument to a docking station (18) having a casing (24) having at least one signal port (32) and a mounting rail (26) mounted within a recessed portion of the casting. The signal ports may be power or data communications ports. A back panel (76) forms part of an instrument housing for housing the instrument, a first portion (52) protrudes rearward from the back panel and a first recess (56) is carried by the protruding portion. The first recess is dimensioned to receive the mounting rail. A rail cam (60) is rotatably mounted within the protruding portion and is aligned with the first recess to receive and retain the mounting rail and at least one first-portion signal port carried by the first portion. The first portion is dimensioned to fit within the recessed portion of the casing such that the rail cam is positioned to receive the mounting rail and the at least one first-portion signal port is aligned, in a complementary fashion, with the at least one casing signal port. A pole clamp assembly (72) may be positioned near the first and second portions. A pivot member (502) is moveable between a retracted position and an extended position and a post (504) having an axis. The post is mounted to the pivot member for axial movement and mounted thereto such that when the pivot member is retracted the axis of the post is substantially parallel with the back panel and when the pivot member is extended the axis of the post is substantially perpendicular to the back panel. <IMAGE>