baber/WOPTO huggingface dataset:
Patent AU-2018329956-A1 (AU)
Title: Agents modulating beta-catenin functions and methods thereof
Inventor: HILINSKI GERARD
IPC: A61K38/08
Filed: 2018-09-07
Abstract: Among other things, the present disclosure provides technologies for modulating functions of beta-catenin. In some embodiments, the present disclosure provides stapled peptides that interact with beta-catenin. In some embodiments, provided stapled peptides interact with beta-catenin at an Axin-binding site of beta-catenin. In some embodiments, the present disclosure provides compounds, compositions and methods for preventing and/or treating conditions, disorders and diseases that are associated with beta-catenin.
Patent AU-2018334019-A1 (AU)
Title: Method for producing a porous sintered magnesia, batch for producing a coarse ceramic refractory product having a granular material made of the sintered magnesia, such a product and method for its production, lining of an industrial furnace, and industrial furnace
Inventor: KLISCHAT HANS-JÜRGEN
IPC: C04B35/043
Filed: 2018-09-13
Abstract: The invention relates to: a method for producing a granulation from sintered magnesia, wherein the sintered magnesia is produced via the sintering of pressed articles, in particular pellets, made of MgO powder, preferably MgO caustic powder, and then mechanically crushing the pressed articles, wherein they are sintered in such a way that the granulation has a grain porosity (total porosity) of 15 to 38 vol.%, preferably 20 to 38 vol.%; according to DIN EN 993-1:1195-04 and DIN EN 993-18:1999-01; and a backfill for producing a heavy-clay refractory, formed or unformed product containing the porous sintered magnesia; a product of this type produced from the backfill; and a method for the production thereof; as well as a lining, in particular a working lining and/or a brick back wall, of a high-volume industrial furnace, wherein the lining, in particular the working lining and/or the brick back wall, has at least one product of this type; and an industrial furnace of this type.
Patent AU-2018347774-A1 (AU)
Title: Aerosol provision systems
Inventor: HEPWORTH RICHARD
IPC: A61M15/06
Filed: 2018-10-11
Abstract: A consumable component for an aerosol provision system comprising: an outer housing comprising an outer wall extending between first and second end walls to define an interior chamber; a plurality of elements of solid aerosol forming material for generating an aerosol for user inhalation, wherein the plurality of elements of solid aerosol forming material are retained within the interior chamber by the housing and wherein the first and second end walls comprise openings to allow air to flow into the interior chamber through the first end wall and out of the interior chamber through the second end wall during use, and a heater located within the interior chamber and configured to heat the elements of solid aerosol forming material during use to generate a vapour for user inhalation.
Patent AU-2018397668-A1 (AU)
Title: Compositions for the management of hyperglycemia and related conditions
Inventor: MAJEED MUHAMMED
IPC: C12N15/81
Filed: 2018-12-26
Abstract: Disclosed is a method for therapeutic management of hyperglycemia in mammals using compositions containing thymohydroquinone. More specifically, the invention discloses compositions containing thymohydroquinone for inhibiting the activity of the enzyme α- glucosidase and increasing the cellular uptake of glucose by mammalian cells. The antioxidant, anti-inflammatory and anti-glycation effects of thymohydroquinone are also disclosed herein.
Patent AU-2018445217-A1 (AU)
Title: Apparatus and method of performing a group communication
Inventor: LIU JIANHUA
IPC: H04W4/08
Filed: 2018-10-09
Abstract: An apparatus and a method of performing a group communication are provided. The method performing the group communication of a user equipment (UE) includes transmitting, to at least one group member in a group communication system, at least one data, and initiating, to a session management function (SMF) node in the group communication system, a group specific packet data network (PDU) session establishment request in the group communication system.
Patent WO-2020087126-A1 (WO)
Inventor: MASTERS SETH
IPC: A61P25/28
Filed: 2019-10-31
Abstract: The present invention relates to methods for treating or preventing TDP-43 proteinopathies, such as amyotrophic lateral sclerosis (ALS) and frontotemperal lobar degeneration (FTLD). The present invention also relates to methods of diagnosing TDP-43 proteinopathies.
Patent AU-2019201571-A1 (AU)
Title: System, cartridge, beverage preparation unit and method for producing a beverage
Inventor: KRÜGER MARC
IPC: B67D1/00
Filed: 2019-03-07
Abstract: Disclosed is a system for producing a beverage, in particular a cold beverage, comprising a cartridge that has a reservoir filled with a beverage substance, a beverage preparation unit with a cartridge receptacle into which the cartridge can be reversibly inserted, and a cartridge discharge device which causes at least partial transfer of the beverage substance from the reservoir into a mixing chamber; furthermore, the beverage preparation unit comprises a fluid supply which opens into the mixing chamber, or the system includes a movable plunger which is placed inside the reservoir and can be transferred from a starting position into a final position by means of the cartridge discharge device. Fig. 5 WO 2017/121799 PCT/EP2017/050564 2 16,34 15-, 8 9-8 1Fig. 3 Fig. 4 --- 27, 28 13 . . .. . . 14 6, 7 Fig. 5
Patent AU-2019202433-A1 (AU)
Title: DNA antibody constructs and method of using same
Inventor: WEINER DAVID B
IPC: A61K39/395
Filed: 2019-04-08
Abstract: Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody. Also disclosed herein is a method of generating a synthetic antibody in a subject by administering the composition to the subject. The disclosure also provides a method of preventing and/or treating disease in a subject using said composition and method of generation.
Patent AU-2019203422-A1 (AU)
Title: IL-15/IL-15 Ralpha based conjugates purification method
Inventor: BECHARD DAVID
IPC: C07K14/435
Filed: 2019-05-15
Abstract: The present invention relates to a method for preparing a composition comprising monomeric conjugates from a sample, said conjugate comprising (a) a polypeptide comprising the amino acid sequence of interleukin 15 or derivatives thereof, and (b) a 5 polypeptide comprising the amino acid sequence of the sushi domain of IL-15Ra or derivatives thereof; wherein said method comprises the use of anion-exchange chromatography followed by a hydrophobic interaction chromatography; and to a pharmaceutical composition which can be obtained by such a method.
Patent AU-2019210586-A1 (AU)
Title: Memory expansion board with random number generator
Inventor: DARANYI SANDOR
IPC: A63F13/77
Filed: 2019-07-31
Abstract: A gaming device comprises a main board comprising a processor, a 
memory storing system program code and an expansion port in data 
communication with a memory interface of the processor, and a memory 
expansion board connected to the main board via the expansion port. The 
memory expansion board comprises a device configured to execute a random 
number generator and write random numbers into one or more registers of the 
memory expansion board accessible by the main board, and at least one 
connector for connecting a memory module comprising game program code.  
When the processor requires random numbers, the system program code causes 
the processor to read random numbers from the one or more registers of the 
memory expansion board.
CONNECT MEMORY EXPANSION BOARD HAVING 410 
RANDOM NUMBER GENERATOR 
UPDATING SYSTEM SOFTWARE TO READ 420 
RANDOM NUMBERS FROM THE MEMORY 
EXPANSION BOARD 
400 
FIG. 4
Patent AU-2019212565-A1 (AU)
Title: Ophthalmic pharmaceutical composition, preparation method therefor and application thereof
Inventor: LIU ZUGUO
IPC: A61K9/08
Filed: 2019-01-22
Abstract: An ophthalmic pharmaceutical composition, a preparation method therefor and an application thereof, the pharmaceutical composition comprises an alanyl-glutamine dipeptide suspended or dissolved in an ophthalmically acceptable isotonic solution.
Patent AU-2019213454-A1 (AU)
Title: 7,8-dihydoxyflavone and 7,8-substituted flavone derivatives, compositions, and methods related thereto
Inventor: YE KEQIANG
IPC: A61P25/00
Filed: 2019-08-12
Abstract: In certain embodiments, the disclosure relates to 7,8-dihydoxyflavone and 7,8 substituted flavone derivatives, such as those described by formula provided herein, 5 pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or preventing diseases or conditions related to BDNF and TrkB activity, such as psychiatric disorders, depression, post-traumatic stress disorder, and autism spectrum disorders, stroke, Rett syndrome, Parkinson's disease, and Alzheimer's disease by administering effective amounts of pharmaceutical compositions 10 comprising compounds disclosed herein to a subject in need thereof In certain embodiments, it is contemplated that the 7,8-substituted flavone derivatives disclosed herein are prodrugs of 7,8-dihydoxyflavone and analogs. (z) 0 0 0 cC' R: O NN H I o R6 R7 R1 R12 HO ,N ON N~ + RCOOH RO O 2 i Npyridine OR THF, 4 N HCI OR RO in dioxane RO 0 SUBSTITUTE SHEET (RULE 26)
Patent AU-2019221104-A1 (AU)
Title: Polymorphous reservoir
Inventor: ROBINET PASCAL
IPC: C01B3/00
Filed: 2019-02-06
Abstract: The present invention relates to a deformable reservoir (1) for storing solid hydrogen, containing at least one compound (2) that can absorb or release hydrogen, and characterised in that it comprises at least: - two rigid bars (3) each comprising a polymer liner (4) defining at least one compartment (5) for storing the compound (2) and accommodated inside a reinforcing structure (6) having globally the shape of a hollow cylinder closed at each of its longitudinal ends by a closing flange (7, 8), - a connection (13) attached to the reinforcing structure (6) of at least one of the bars (3) so as to be sealed to the liner (4), - a flexible union member (9) joining two adjacent bars (3) so as to allow the totality of the storage reservoir (1) to be deformable in spite of the rigidity of each bar (3).
Patent AU-2019222948-A1 (AU)
Title: Magnetic resonance imaging (MRI) image filtration according to different cardiac rhythms
Inventor: GOVARI ASSAF
IPC: G06Q50/00
Filed: 2019-08-30
Abstract: A method includes receiving a plurality of voxel values corresponding to respective locations in a heart, which are acquired using magnetic resonance imaging (MRI). 5 Voxel values that, in spite of (i) corresponding to a same location in the heart and (ii) being gated to a same phase of an electrocardiogram (ECG) cycle of the heart, differ by more than a predefined difference, are identified. An image of at least a portion of the heart is reconstructed 10 from the plurality of voxel values excluding at least the identified voxel values. 00 14. 0) CV) CY) CIO Q) Do clq f CV) It LO CY) clq CY) CY) d I-ftft
Patent AU-2019232404-A1 (AU)
Title: Agricultural mesh for baling
Inventor: VIOLAS DE OLIVEIRA E SÁ PEDRO AMÉRICO
IPC: B65D65/38
Filed: 2019-02-26
Abstract: The present invention relates to an agricultural mesh for baling (1) comprising columns of chains or pillars ( 3), wherein each column of chain or pillar ( 3) comprises a plurality of meshes ( 4) interconnected with each other and associated with the columns of chains or pillars (3) by means of the wefts (2), wherein the configuration and dimensions of the wefts (2) provides the reinforcement of the agricultural mesh for baling (1). The present invention provides a solution that aims to reduce the dimensions of the longitudinal openings wefts ( 2) during the baling process, yielding strong and well- preserved bales.
Patent AU-2019253918-A1 (AU)
Title: System and methods for mitigating fraud in real time using feedback
Inventor: TAYLOR LUKE ANTHONY JAMES
IPC: G06Q30/02
Filed: 2019-04-17
Abstract: An embodiment of a feedback-based system and methods are disclosed for real-time mitigation of fraud and otherwise invalid traffic in a mobile ad environment. The system of three complementary facets of one embodiment comprises four major subsystems: prevention, detection, control and reporting, which work in cohesion with one another to achieve the common goal of the system. In the embodiment, deterministic and probabilistic methods are applied across all levels of user engagement (impressions, clicks, installs, post-install events, and conversions) to detect the likely sources of invalid traffic and block them in real time. A distinctive and unifying feature of the embodiment of the system is the feedback loop that connects advanced analytics and machine learning techniques that the detection subsystem employs at all levels of user engagement to the real-time blocking mechanism of the prevention subsystem that operates at the initial levels of user engagements, such as clicks and impressions. Embodiments of the invention can help ad networks and advertisers improve their competitive positions in their respective fields by significantly reducing the negative impact of mobile ad fraud.
Patent AU-2019263851-A1 (AU)
Title: Handheld vacuum cleaner
Inventor: YU HAO
IPC: A47L5/24
Filed: 2019-04-30
Abstract: A handheld vacuum cleaner, comprising: a dust-air separation unit (10), an airflow generating unit, a battery pack assembly (20), and a handle (30); the dust-air separation unit (10) is provided with a dust suction inlet that defines a longitudinal axis (X) extending along the front-rear direction; the airflow generating unit is provided with an air inlet side (4) and an air outlet side (6), and the air inlet side (4) communicates with the dust-air separation unit (10); an outer wall of the handheld vacuum cleaner is provided with an internally and externally penetrating air outlet (5), wherein the air outlet (5) communicates with the air outlet side (6) of the airflow generating unit, and the air outlet (5) is configured to at least partially exceed the airflow generating unit towards the front in the dust-air suction direction located along the longitudinal axis (X). Compared with existing technology, heat emitted by a fan (2) may be promptly discharged, the temperature of the fan (2) may be reduced when using the vacuum cleaner, the service life of the fan (2) is lengthened, and a discharged airflow will not directly blow on a user when using the vacuum cleaner.
Patent AU-2019265632-A1 (AU)
Title: Particles for spatiotemporal release of agents
Inventor: FAHMY TAREK
IPC: A61K47/59
Filed: 2019-05-08
Abstract: Particles with a spatial and/or temporal release profile for delivery of different agents at different times to the same cells of a subject have been developed. The particles include a core polymeric particle containing a polymer and a first agent, a tethering moiety, covalent linker or covalent linkage attached to the core particle, and a tethered particle attached to the particle via the tethering moiety, covalent linker or covalent linkage and containing a second agent, where the agents are released at different times within or to the same cells. The first and second agents may be a therapeutic or prophylactic agent, such as an antigen, an immunomodulator, an anti-neoplastic agent, a hormone, an inhibitor, etc. The particles may form compositions for treating diseases with a spatial and/or temporal treatment regimen.
Patent AU-2019283457-A1 (AU)
Title: Interface assemblies for respiratory therapy
Inventor: FARROW ABBY REBECCA
IPC: A61M16/06
Filed: 2019-06-04
Abstract: In some embodiments there is provided a headgear assembly for a full-face under-nose respiratory mask comprising a strap assembly including a rear panel, a crown strap, a pair of opposing upper side straps, and a pair of opposing lower side straps. The assembly further comprises a flexible headgear connector element, wherein a free end of each of the upper straps is coupled to the headgear connector element, and wherein the headgear connector element is configured to extend laterally across and be removably fastened to a frame of the respiratory mask below a tip of a user's nose. There is also provided a respiratory mask assembly comprising a mask frame and a cushion module, the mask frame comprising a breathing gas inlet configured to receive a supply of breathable gas and to deliver the breathable gas to the cushion module, the cushion module being configured to form a seal with a user's face. The mask assembly can further comprise a bias vent in communication with the cushion module, and configured to allow air to be exhausted from the cushion module through the bias vent. the bias vent can be provided with a diffuser comprising diffuser material configured to extend over the bias vent, the diffuser material providing a tortuous air path from the bias vent through the diffuser. Embodiments are disclosed in which the bias vent and/or diffuser are provided on various components of the assembly.
Patent AU-2019321432-A1 (AU)
Title: Treatment of B cell malignancies
Inventor: GOLD DANIEL P
IPC: A61K31/5377
Filed: 2019-08-13
Abstract: Provided herein are methods of treating cancer using a phosphoinositide-3-kinase (PI3K) inhibitor. In certain embodiments, the cancer is follicular lymphoma (FL). In certain embodiments, the PI3K inhibitor is administered on a continuous dosing schedule (CS). In other embodiments, the PI3K inhibitor is administered on an intermittent dosing schedule (IS).
Patent AU-2019328632-A1 (AU)
Title: Combination therapies comprising CD137/HER2 bispecific agents and PD-1 axis inhibitors and uses thereof
Inventor: BRUNS INGNAR
IPC: A61P35/00
Filed: 2019-08-27
Abstract: The disclosure provides compositions and methods for treating previously treated specific HER2-positive advanced or metastatic solid tumors. The disclosure provides compositions and methods for enhancing immune response in an individual having HER2-positive advanced or metastatic solid tumors. The method comprises administering a PD-1axis inhibitor and a bispecific agent that targets CD137 and HER2.
Patent AU-2019335644-A1 (AU)
Title: Installation method and installation device for fluid control device
Inventor: KANETA Naoki
IPC: F16L55/00
Filed: 2019-07-18
Abstract: Provided are an installation method and an installation device for a fluid control device, with which the positional accuracy of a valve body inserted into a hole formed in a fluid pipe in a case can be improved, controllability of a fluid in the pipe can be increased, construction equipment such as a flow control valve installation device and an operation valve device can be made more compact and lightweight, and the cost thereof can be reduced. In this installation method, in which a fluid control device (having at least a case 5 installed in a sealed state on a fluid pipe 1, and a flow control valve 10 equipped with a valve casing 12 and a valve body 11 that can be inserted into a hole 1b formed in the fluid pipe 1 in the case 5) is installed in a continuous flow state, an operation valve device 3 equipped with an operation valve body 31 for portioning the interior of the case 5 in an openable/closable manner is attached to an opening 5b formed in a neck portion 5d of the case 5, the operation valve body 31 is opened while an open end portion 5c formed in the neck portion 5d is surrounded in a sealable manner, and the fluid control valve 10, which communicates with the interior of the case 5 in a sealed state, is inserted from the open end portion 5c to an installation position at which the tip end of the valve casing 12 of the flow control valve 10 is inserted beyond the opening 5b of the neck portion 5d, thereby sealing the interval between the peripheral surface of the valve casing 12 and the peripheral surface of the neck portion 5d by means of an annular sealing member 21 in the installation position.
Patent AU-2019347849-A1 (AU)
Title: 2'FANA modified Foxp3 antisense oligonucleotides and methods of use thereof
Inventor: AISHWARYA VEENU
IPC: A61P35/00
Filed: 2019-09-25
Abstract: The present invention is directed to hybrid chimera antisense oligonucleotides including deoxyribonucleotide and 2'-deoxy-2'-fluoro-β-D-arabinonucleotide which binds to a
Patent AU-2019364436-A1 (AU)
Title: HLA-A3–restricted T cell receptors against mutated RAS
Inventor: HANADA KENICHI
IPC: C07K14/725
Filed: 2019-10-24
Abstract: Disclosed is an isolated or purified T cell receptor (TCR), wherein the TCR has antigenic specificity for a mutated RAS amino acid sequence presented by a HLA-A3 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
Patent AU-2019396127-A1 (AU)
Title: A water-based explosive
Inventor: CECHANSKI MICHAEL
IPC: C06B47/14
Filed: 2019-12-11
Abstract: An explosive, in particular a water-in-oil emulsion explosive, comprising a water-based explosive composition and a gas, wherein the gas is infused with two different ranges of sizes of nanobubbles, to provide controlled hotspots for detonation to improve emulsion stability and detonation sensitivity. Into the Nano Bubble tank (31) are fed the pressurised gas in water through valve (26) and also a sample is fed into the Nano Bubble tank (31). This then provides the NanoBubble Input NBIbp1 to be fed by NB Feed Pump (33) into static mixer (51). Also fed to the Static Mixer (51) by matrix pump (41) is the explosives containing PIBSA (Poly-Iso-Butylene Succinic Anhydride) in emulsion form as Emulsion Input EInp1 from Emulsion Matrix truck. The static mixer allows for the gas to be infused into the water-based explosive composition in at least a substantial part in the form of nanobubbles (NB) which then forms a controlled explosive output for use in the blast hole (61) by the bubbles acting as a sensitiser as so called "hot spots" which transfer the energy throughout the explosive charge once initiated. This allows the thermal "hot spot" detonation wave to travel through and carries the explosive to a full and controlled detonation.
Patent AU-2019412342-A1 (AU)
Title: Oncolytic virus expressing interferon and application therefor
Inventor: ZHANG KANGJIAN
IPC: A61K35/761
Filed: 2019-12-24
Abstract: Provided is an oncolytic virus expressing an interferon. Specifically provided is an oncolytic adenovirus expressing an interferon hybrid protein, said oncolytic virus being capable of effectively suppressing tumors in vitro and in vivo.
Patent WO-2021012010-A1 (WO)
Inventor: VINCAN ALEXANDER
IPC: B60P1/28
Filed: 2020-07-24
Abstract: Embodiments herein provides a system for creating an adhesive bond using elastomeric material. The system includes the steps of (i) a first material, the first material having a first material length and a first material width, (ii) a second material, the second material having a second material length and a second material width, (iii) a gap between the first material and the second material, (iv) an elastomeric material substantially filling at least a portion of the height and length of the gap between the first material and the second material. The gap includes a height and a length. The height being substantially equal to a distance between the first material and the second material and the length being substantially orthogonal to the height and defined by a degree of overlap between the first and second materials.