baber/WOPTO huggingface dataset:
Patent EP-4001277-A2 (EP)
Inventor: MOLETTE JÉRÔME
IPC: A61P25/00
Filed: 2017-03-10
Abstract: The present invention relates to novel compounds that can be employed in the diagnosis, monitoring of disease progression or monitoring of drug activity, of a group of disorders and abnormalities associated with alpha-synuclein (a-synuclein, A-synuclein, aSynuclein, A-syn, α-syn, aSyn) aggregates including, but not limited to, Lewy bodies and/or Lewy neurites, such as Parkinson's disease. The instant compounds are particularly useful in determining a predisposition to such a disorder, monitoring residual disorder, or predicting the responsiveness of a patient who is suffering from such a disorder to the treatment with a certain medicament. The present compounds can also be used to treat, alleviate or prevent a disorder or abnormality associated with alpha-synuclein aggregates.
Patent EP-4139283-A2 (EP)
Inventor: WALDVOGEL SIEGFRIED R
IPC: C25B9/19
Filed: 2021-04-23
Abstract: The present invention relates to regioselective chemical and electrochemical processes for the preparation of an oxidized heterocyclic alpha-amino amide compounds. By applying specific catalysts or catalyst systems during chemical oxidation or by applying particular electrochemical oxidation conditions the present invention provides access to valuable alpha amino amide compounds, which are oxidized at the heterocyclic amino group by regioselective introduction of either a hydroxyl or a keto group. In a more particular embodiment, the present invention describes a chemical oxidation reaction, which advantageously is applicable in the enantioselective synthesis of valuable oxidized heterocyclic alpha-amino amide compounds, like levetiracetam, brivaracetam or the synthesis of piracetam. Another aspect of the present invention relates to a process for the electrochemical recycling of alkali perhalogenate oxidants as spent during said regioselective oxidation reactions of the invention. Still another aspect of the invention relates to the electrochemical preparation of perhalogenates.
Patent EP-4143854-A2 (EP)
Inventor: SIVACK MICHAEL R
IPC: G21C3/324
Filed: 2021-05-03
Abstract: Channel boxes for a boiling water reactor and methods of manufacture thereof are provided. The channel box comprises a substrate and a first layer. The substrate comprises a tubular shape. The substrate comprises silicon carbide fibers. The first layer is deposited on a first surface of the substrate and the first layer comprises a corrosion resistant metallic composition.
Patent EP-4147748-A2 (EP)
Inventor: WEY ALBERT CHIN-TANG
IPC: A61N5/06
Filed: 2022-08-08
Abstract: This invention relates to a ceramic module for assembly into a therapeutic device for treating a human or animal body with irradiation of far infrared. More specifically, said ceramic module can simultaneously emit blackbody-like thermal radiation and stimulated FIR-photons radiation in 3 - 16 µm wavelength spectrum, while the overall radiation in 8 - 14 µm wavelength range is measured to be an approximated blackbody radiation at a temperature that is at least 1 °K (or 1 °C) higher than the actual body temperature of said ceramic module, signifying an effective emissivity greater than 1.0. Said ceramic module may be used alone or serve as components of a therapeutic device for increasing physiologic performance, immune competence, health, and mean lifespan of human or animal.
Patent EP-4294528-A2 (EP)
Inventor: ATTAR RICARDO MARCOS
IPC: A61P35/00
Filed: 2022-02-15
Abstract: Provided herein are multispecific antibodies that bind to BCMA, GPRC5D and CD3 and multispecific antigen-binding fragments thereof. Also described are related polynucleotides capable of encoding the provided multispecific antibodies or multispecific antigen-binding fragments, cells expressing the provided multi specific antibodies or multispecific antigen-binding fragments, as well as associated vectors and detectably labeled multispecific antibodies or multispecific antigen-binding fragments. In addition, methods of producing and using the provided multispecific antibodies and multispecific antigen-binding fragments are described. Further provided herein are antibodies that bind to BCMA and antigen-binding fragments thereof. Also described are related polynucleotides capable of encoding the provided BCMA-specific antibodies or antigen- binding fragments, cells expressing the provided BCMA-specific antibodies or antigen- binding fragments, as well as associated vectors and detectably labeled BCMA-specific antibodies or antigen-binding fragments. In addition, methods of producing and using the provided BCMA-specific antibodies and antigen-binding fragments are described.
Patent EP-4233860-A2 (EP)
Title: Nutritional compositions and infant formula for promoting de novo myealination
Inventor: SCHNEIDER NORA
IPC: A61K31/40
Filed: 2016-12-13
Abstract: The invention relates to a synthetic nutritional composition comprising a mineral for use to promote, support or optimise de novo myelination, in particular the de novo myelination trajectory, and/or brain structure, and/or brain connectivity, and/or intellectual potential and/or cognitive potential and/or learning potential and/or cognitive functioning in a subject, in particular a formula fed subject.
Patent EP-4282496-A2 (EP)
Inventor: INOUE HIDETAKA
IPC: A63B37/00
Filed: 2023-04-27
Abstract: An object of the present disclosure is to provide a golf ball having excellent flight distance on driver shots and good spin rate on middle iron shots. The present disclosure provides a golf ball comprising a spherical core and a cover, wherein a hardness difference (C1-C0), a hardness difference (C2-C1), a hardness difference (C3-C2) and a hardness difference (C4-C3) are more than 0 and 6.0 or less, a hardness difference (C5-C4) is 5.0 or more, and a hardness difference (C6-C5), a hardness difference (C7-C6) and a hardness difference (C8-C7) are more than 0 and 3.5 or less where C0 (center), C1, C2, C3, C4, C5, C6, C7 and C8 (surface) are a Shore C hardness at each point from the center obtained by dividing a radius of the spherical core into equal eight parts
Patent EP-4243323-A2 (EP)
Inventor: SHI JING
IPC: H04L5/00
Filed: 2020-09-17
Abstract: Provided are an information determination method and device, an information adjustment method, a threshold usage method, a terminal, and a storage medium. The information determination method includes: determining a second threshold of a target subcarrier spacing according to the number of cells that meet a first set condition, the total number of downlink cells, the number of supported cells reported by a terminal, and a first threshold.
Patent EP-4238522-A2 (EP)
Title: System and method for intraoperative surgical planning
Inventor: BISCHOFF JEFFREY E
IPC: A61B34/10
Filed: 2017-06-16
Abstract: The subject matter includes systems, methods, and prosthetic devices for joint reconstruction surgery. A computer-assisted intraoperating planning method can include accessing a first medical image providing a first view of a joint within a surgical site as well as receiving selection of a first component of a modular prosthetic device implanted in the first bone of the joint. The method continues by displaying a graphical representation of the first component of the modular prosthetic device overlaid on the first medical image, and updating a graphical representation of the first component based on receiving positioning inputs representative of an implant location of the first component relative to landmarks on the first bone visible within the first medical image. The method concludes by presenting a selection interface enabling visualization of additional components of the modular prosthetic device virtually connected to the first component and overlaid on the first medical image.
Patent EP-4238599-A2 (EP)
Inventor: BAUER BENJAMIN DAVID
IPC: A61M5/315
Filed: 2019-02-20
Abstract: Dose detection systems for medication delivery devices are described. One is a module for removable attachment to a dose button of a medication delivery device. A device with a dose detection system is also disclosed. The module includes a processor and a plurality of magnetic sensors, such as, for example, five or six sensors, operably coupled to the processor and configured to detect the positon of a rotating bipolar magnetic ring within the delivery device. Medication identification system may also be provided.
Patent EP-4239732-A2 (EP)
Inventor: NESSELBERGER MARKUS
IPC: H01M4/90
Filed: 2017-10-23
Abstract: Die vorliegende Erfindung betrifft eine Katalysatorzusammensetzung, umfassend- ein Trägermaterial in Form von Kohlenstoffpartikeln,- metallische Platinpartikel, die auf dem Trägermaterial vorliegen und eine Volumengewichtete Partikelgrößenverteilung, bestimmt über Röntgenkleinwinkelstreuung, mit einem d<sub>10</sub>-Wert ≥ 2,0nm und d<sub>90</sub>-Wert ≤ 7,0 nm aufweisen.
Patent EP-4258578-A2 (EP)
Inventor: ZHANG YUSHU
IPC: H04L1/1607
Filed: 2015-12-10
Abstract: There is provided an apparatus of a network entity, comprising circuitry adapted to: receive, from a user equipment, UE, a combined scheduling request, SR, and a buffer status report group indicator, BSRGI, in a single subframe. Wherein a buffer status report, BSR, is divided into two or more groups and the BSRGI is used to indicate to which BSR group the BSR belongs. Wherein a value of the BSRGI is based on a BSR group threshold indicating a maximum buffer size for the value of the BSRGI. Wherein the BSR group threshold is based on a power control factor of the UE or uplink Channel State Information, CSI, for the UE. Wherein the BSRGI is added to an end of the CSI. The circuitry is further adapted to configure uplink resource scheduling in reply to the combined SR and BSRGI and transmit, to the UE, the uplink resource scheduling.
Patent EP-4283400-A2 (EP)
Title: Measurement apparatus, lithography apparatus and article manufacturing method
Inventor: YAMAGUCHI WATARU
IPC: G03F9/00
Filed: 2022-01-04
Abstract: The present invention provides a measurement apparatus for measuring a position of a first pattern and a position of a second pattern provided in a target object, the apparatus including an image capturing unit including a plurality of pixels which detect light from the first pattern and light from the second pattern, and configured to form an image capturing region used to capture the first pattern and the second pattern by the plurality of pixels, and a control unit configured to adjust the image capturing unit such that a relative ratio of an intensity of a detection signal of the first pattern generated based on an output from a first image capturing region and an intensity of a detection signal of the second pattern generated based on an output from a second image capturing region falls within an allowable range.
Patent EP-0015646-A2 (EP)
Inventor: ENEVER JAMES ALEXANDER
IPC: C06B47/14
Filed: 1980-02-04
Abstract: A powder explosive composition comprising particulate inorganic oxidising salt, finely divided metal sensitiser and, optionally additional fuel consisting of discrete granules containing oxidising salt and sensitising metal coated with a tough, cohesive, resilient gelled solution of the oxidising salt, the amount of the coating being insufficient to form a continous gelled phase. The composition is more water resistant, less dusty and less sensitive to friction and impact than the metal sensitised powder compositions of the prior art.
Patent EP-0036077-A2 (EP)
Inventor: SIMON LIONEL NORTON
IPC: C07F9/38
Filed: 1981-02-12
Abstract: There are prepared compounds of the formula
     where R 1  is alkyl of 1 to 8 carbon atoms and R 2  is the ester group of an unsubstituted monocarboxylic acid, aromatic carboxylic acid, aminocarboxylic acid, unsubstituted dicar. boxylic acid. phosphoric acid. or nitric acid or a glycoside or an acetaldehyde acetal The compounds are immunomodulators. have antiviral activity and antitumor activity and also are enzyme inhibitors. The compounds can also be used to introduce the corresponding alcohol into biological systems, in some cases with enhanced potency.
Patent EP-0043515-A2 (EP)
Inventor: SCHONHARDT PETER
IPC: H01H43/10
Filed: 1981-06-26
Abstract: The invention relates to a timer with a switch ring driven by a clock, with plug-in switch riders, with a switch star which is turned on to particular rotational angled positions of the switch ring, determined by the insertion positions of the switch riders, and in this way opens or closes the electrical contact set of the timer. According to the invention, the timer is characterised in that the switch star (10) can be rotated via a toothed ring (13), coupled to the switch star (10) and arranged rotatably and concentrically to the switch ring axis (perpendicular to the plane of the drawing), in that the switch riders (5) can be plugged in on a fixed part of the timer near the circumferential switch ring (7), in that, on the switch ring (7), a coupling element (15) is provided which, as it passes by a switch rider (5) is moved by the cam (6) of the latter such that it is coupled into the toothed ring (13) and takes the latter with it so far that the switch star (10) is rotated on by one notch position.
Patent EP-0054296-A2 (EP)
Inventor: ONO KIMIZO SUMITOMO ELECTRIC I
IPC: A61B18/20
Filed: 1981-12-14
Abstract: An attachment device for connecting first and second parts of a laser device comprises a groove in one part, a mating pin in the other and a spring-biased collar for securing the pin the groove.
Patent EP-0032829-A2 (EP)
Inventor: SCHNEIDER JOHN RUSSEL
IPC: B01D25/12
Filed: 1981-01-16
Abstract: A liquid filtering medium supply and extraction mechanism comprises a driven roller (42) for each sheet of filter media in combination with an adjacent, movable bar (60) having a series of spaced apart pinch wheels (62) mounted thereon for penetrating accumulated cake and filtered dirt on the media when an actuator moves them against the roller as the media is being advanced. The driven rollers (42) are mounted on separate bearing plates (70) which are movable in response to sensor signals (100) to steer the moving filter media and maintain its alignment with the filter plates. The supply section of the apparatus comprises a series of supports for supply rolls (30) of filter media provided with adjustable centering means (126) to help maintain proper alignment of the filter media between filter plates.
Patent EP-0066035-A2 (EP)
Inventor: BIEBL HANS DIPL ING
IPC: F03D7/02
Filed: 1981-10-30
Abstract: The effect of an orientation device for a down-wind mounted wind wheel whose impeller 3 is arranged in a known way by means of its hub 2 on the stub of the axle of an energy converter 1, preferably an electrical generator, this unit being arranged by means of a thrust bearing 4, arranged on the housing of the energy converter 1, so as to swivel horizontally on the top of a vertical standpipe 5, is that the unit positions itself into the wind direction even if the latter suddenly changes by approximately 90 DEG . Said device consists of a tubular control part 8, preferably in the form of the lateral surface of a circular cylinder, which is coaxially arranged on the free end of an axial extension 7 on the side of the impeller hub 2 averted from the energy converter 1, and which for the purpose of increasing the air resistance by vortex formation can have a number of holes 10 arranged in a uniform distribution. <IMAGE>
Patent EP-0071891-A2 (EP)
Inventor: TAKAYA TAKAO
IPC: C07D501/34
Filed: 1982-07-29
Abstract: A compound of the formula: 
<CHEM>
 wherein
 R<1> is carboxy(lower)alkyl or protected carboxy(lower)alkyl,
 R<2> is carboxy or protected carboxy,
 R<3> is hydrogen or lower alkyl, and
 R<4> is lower alkyl, lower alkoxy, acyloxymethyl, lower alkylthiomethyl, lower alkoxymethyl, halogen, lower alkenyl or hydrogen,
 and pharmaceutically acceptable salts thereof, and processes for the preparation thereof and also an antibacterial composition comprising the above compound in association with pharmaceutically acceptable carriers. The invention further relates to intermediate compounds of the formula 
<CHEM>
 and the preparation thereof.
Patent EP-0076408-A2 (EP)
Inventor: SWANEY RICHARD E
IPC: G06F13/14
Filed: 1982-09-17
Abstract: A method of functional addressing which may be employed with a multiplexed data bus having a plurality of data processing units coupled thereto. A function code is generated and made part of a transmitted message. Units receiving the transmitted message apply the function code to the address lines of a random access memory and read the contents of the memory at a location indicated by the function code. The contents stored at each memory location are indicative of whether or not that type of message is accepted or disregarded by the receiving unit. Also, a method of changing the contents of the memory, and hence the routing of messages between units, is disclosed.
Patent EP-0074687-A2 (EP)
Inventor: LUTTEKE GEORG
IPC: H03B5/18
Filed: 1982-09-09
Abstract: Einem Mikrowellen-Oszillator in Gegentaktschaltung zur Erzeugung von Oberschwingungen wird auch Energie der Grundschwingung entnommen.
Patent EP-0067635-A2 (EP)
Inventor: BOLICH RAYMOND EDWARD JR
IPC: C11D1/00
Filed: 1982-06-07
Abstract: Shampoo compositions containing an unsaturated quaternary ammonium compound and surfactant selected from betaines and mixtures of betaines and sultaines, which compositions exhibit improved low temperature stability due to the inclusion of a long chain acyl derivative.
Patent EP-0057651-A2 (EP)
Inventor: SEPTIER LOUIS LES CHAMOIS
IPC: C09K3/14
Filed: 1982-01-26
Abstract: A method and apparatus is disclosed for rapidly solidifying and cooling molten metal oxides, by continuous casting, which according to the invention, comprises: feeding the molten metal oxides into the convergent space formed between two cylinders mounted for rotation about horizontal axes and rotated in opposite directions, i.e., counter-rotating, at a substantially equal peripheral speed, the distance between their axes being equal to the sum of the radius of each cylinder plus at least about one millimeter; cooling the walls of the cylinders to enable solidification of the molten material; controlling the rotary speed of the cylinders so that the molten metal oxide is not completely solidified until it reaches a point beyond a plane passing through the axes of rotation of the cylinders, and retrieving a solidified metal oxide product from the divergent space formed between the cylinders. The method is particularly suited to the production of fine grain abrasives of a corundum or courndum-zirconia base.
Patent EP-0066525-A2 (EP)
Inventor: HILER ALBERT R
IPC: D04B35/34
Filed: 1982-08-10
Abstract: 1. Device for cutting the same weft thread (11) of a plaited or knitted article at several locations on a shot-type knitting machine incorporating, in particular, needles (4) with latches (15) having a to-and-fro movement between a low position and a high position, slots (6) for closing the latches (15) of the needles in the low position, bodkins (2) for arranging a warp thread (12) round each needle (4) with a latch (15) at the locations where stitches are made round the weft threads, and holding-down sinkers (8) having grooves (14) for receiving each weft thread which has been surrounded by stitches, the said device being characterised in that it comprises cutting elements (13) arranged fixedly on the needle (4)-carrying bar (3) and thus having the same to-and-fro movement as the needles (4), and making it possible to sever the said weft thread (11) at several locations simultaneously, just after it has passed into the grooves (14) of the holding-down sinkers (8) and after each stitch has been tightened round the said weft thread.
Patent EP-0092760-A2 (EP)
Inventor: ROGERS ROBERT M
IPC: B65B11/54
Filed: 1983-04-18
Abstract: In a stretch film wrapping machine an improved control system provides for automatic or manual selection of one of at least two differing width film rolls and provides individualized wrapping parameters dependent upon the film width selected. Automatic film selection is performed in response to signals identifying the height, width and length of a package to be wrapped which characteristics are sensed or measured by a package sensing system (222, 226, 228, 230, 232, 234, 236, 242, 244). Both automatic and manual film selection includes timing controls (600) for synchronizing film gripping and clamping apparatus with underfolding apparatus dependent upon the film selected to provide improved control over the tensioning of film wrapped about individual packages. The improved control system monitors the operation of the wrapping machine to detect jam conditions and stops the machine for such jam conditions. The system also provides for limited reverse operation of the film wrapping machine for jam removal. The rear film underfolder and package pusher are mounted to be moved away from the machine to further facilitate jam removal. The improved control system monitors a film tensioning roller via an electrical switch to verify film draw into the machine. If no film is drawn indicating a film source problem, the machine is stopped.
Patent EP-0106056-A2 (EP)
Inventor: KLINGEL HANS DIPL-ING
IPC: B21D43/18
Filed: 1983-08-11
Abstract: 1. Apparatus for lifting plates, particularly for loading and unloading a machine for working the metal plate and comprising a workpiece feed in at least one coordinate direction, particularly a machine tool, with a lifting member (2) having at least one series of workpiece supports (7), preferably suction means, the basic position of the workpiece supports being variable individually in relation to the lifting member (2), in that the workpiece supports (7) are mounted for longitudinal displacement on at least one rail (6), the lifting member (2) being mounted for upwards and downwards movement in respect of a slide (4), the slide being adapted for movement in respect of a frame (3) in the direction of adjustement of the workpiece supports (7), characterised in that the workpiece supports (7), for variation of their basic position, being adapted for connection to a bar (9) or metal plate adapted for movement in the direction of the rail, the bar (9) or the metal plate being displaceable with the workpiece support or supports (7) in relation to the rail (6) or the slide (4) and in respect of the bar or plate with the workpiece support or supports.
Patent EP-0102049-A2 (EP)
Inventor: REED BRADLEY OLIVER
IPC: B62D11/18
Filed: 1983-08-23
Abstract: A simplified range change mechanism for an infinitely variable, split output, synchronously shifting hydromechanical steering transmission having integral steering and at least three forward ranges having progressively lower torque and higher speed propulsion ratios in successively higher ranges while maintaining positive steer with a constant steering torque ratio in all ranges.
Patent EP-0120993-A2 (EP)
Inventor: HERTELL SIEGFRIED DIPL-ING
IPC: F04C18/332
Filed: 1983-11-30
Abstract: 1. Vane pump particularly for producing a vacuum for increasing the braking power in motor vehicles with Diesel-engines or fuel injection Otto-engines, comprising an internally positioned stator (4) and a rotatable housing (3) having recesses (8) inserted in its inner surface, in which recesses vanes (9) are pivotally mounted with one end, which vanes (9), when being in their retracted position, immerse in the recesses (8) outside of the cylindrical surface enveloping the inner surface, characterized by the fact that the vanes (9) are pivotally mounted in the recesses (8) in such a manner that the free pivoting end of the vanes (9) extends in the direction of rotation and is pivoted by the force of springs so as to come into close contact with the cylindrical stator (4).