baber/WOPTO huggingface dataset:
Patent DO-P2004001027-A (DO)
Title: Formulaciones farmaceuticas
Inventor: AMAR LULLA
Filed: 2004-11-09
Abstract: Formulación farmacéutica que comprende un agenta contra la abesida, como sibutramina, y al menos un acidulante, como ácido fumárico, junto con un transportador, diluyente o excipiente farmacéuticamente aceptable.
Patent DO-P2012000217-A (DO)
Title: Pastillas de gelatina blanda con nicotina
Inventor: THAKKAR JATIN VASANT
Filed: 2012-08-06
Abstract: Se describe una pastilla blanda para el tratamiento de sustitución de Ia nicotina. La pastilla está compuesta por aproximadamente un 0,05 % a un 1 % de principio activo de nicotina; entre un 5 % y un 40 % de agente gelificante; entre un 30 % y un 70 % de plastificante; entre un 0,05 % y un 10 % de edulcorante; entre un 0,5 % y un 30 % de agente liberador; entre un 0,05 % y un 2 % de conservante; entre un 0,01 % y un 5 % de saborizante; y entre un 5 % y un 20 % de agua.
Patent DO-P2020000123-A (DO)
Title: Análogos de incretina y sus usos
Inventor: LILI GUO
IPC: C07K14/605
Filed: 2020-06-17
Abstract: Se proporcionan análogos de incretina que tienen actividad en cada uno de los receptores de GIP, GLP-1 y glucagón. Los análogos de incretina tienen características estructurales que dan como resultado una actividad equilibrada y una duración de acción extendida en cada uno de estos receptores. También se proporcionan métodos para tratar enfermedades tales como diabetes mellitus, dislipidemia, hepatopatía grasa, síndrome metabólico, esteatohepatitis no alcohólica y obesidad.
Patent DO-P2020000131-A (DO)
Title: Combinaciones de lipidos
Inventor: CHARLES HODGSON
IPC: A61P29/00
Filed: 2020-06-22
Abstract: La presente invención se relaciona en general con combinaciones de lípidos marinos. En particular se relaciona con una combinación de lípidos marinos obtenidos de Perna canaliculus y kril, composiciones y preparaciones que comprenden dichas combinaciones y el uso terapéutico de dichas combinaciones y composiciones. También se describen procesos para la elaboración de aceites de kril y su uso en las combinaciones y composiciones.
Patent DO-P2021000273-A (DO)
Title: Agonistas del receptor del péptido-1 similar al glucagón
Inventor: DAVID ANDREW COATES
IPC: C07D405/14
Filed: 2021-12-23
Abstract: En una modalidad, la presente invención proporciona un compuesto de la fórmula: o una sal farmacéuticamente aceptable del mismo, y métodos para usar este compuesto en el tratamiento de la diabetes mellitus tipo II.
Patent EC-SP11010839-A (EC)
Title: Inhibidores cíclicos de 11beta-hidroxiesteroide deshidrogenasa 1
Inventor: HIMMELSBACH FRANK
IPC: C07D413/10
Filed: 2011-02-18
Abstract: Esta invención se refiere a nuevos compuestos de la Fórmula Ik, Im1, Im2, Im5, In1, In2, In5, Io1, Io2, Io5, Ip1, Ip3, a sales farmacéuticamente aceptables de los mismos y a composiciones farmacéuticas de los mismos, que son útiles para el tratamiento terapéutico de enfermedades asociadas con la modulación o inhibición de 11 -HSD1 en mamíferos. La invención también se refiere a composiciones farmacéuticas de los nuevos compuestos y métodos para su uso en la reducción o control de la producción de cortisol en una célula o la inhibición de la conversión de cortisona en cortisol en una célula.
Patent EC-SP13013022-A (EC)
Title: Agonistas de fgfr1 y sus métodos de uso
Inventor: WU YAN
IPC: C07K16/28
Filed: 2013-11-14
Abstract: La invención proporciona agonistas de FGFR1, incluyendo anticuerpos agonista de anti-FGFR1 y sus métodos de uso.
Patent EE-200300024-A (EE)
Inventor: KOOISTRA JACOB HERMANUS MATTHE
IPC: C07D309/30
Filed: 2001-07-12
Abstract: The invention relates to the preparation of 2-(6-substituted-1,3-dioxane-4-yl)acetic acid derivatives of formula 1, where X stands for a leaving group, and R 1 , R 2 , and R 3  each independently stand for an alkyl group with 1-3 carbon atoms from 4-hydroxy-6-X-substituted-methyl-tetrahydropyran-2-one compounds, where X is as defined above, with the aid of an acetalization agent, in the presence of an acid catalyst.  The invention also relates to the novel compounds of formula 1 as well as salts and acids to be prepared from these, with the OR 3  group in formula 1 being replaced by an OY group, where X, R 1  and R 2  have the meanings defined above and where Y stands for an alkaline (earth) metal or a substituted or unsubstituted ammonium group or stands for hydrogen, and to the novel compounds of formula 2.  The products concerned are, after conversion into the t-butyl ester of 2-(6-hydroxymethyl-1,3-dioxane-4-yl)acetic acid, important as intermediary products in the preparation of statins.
Patent GB-189702657-A (GB)
Title: Improvements in Lanterns for use in Gas Lighting.
Inventor: BIHELLER SIMON
Filed: 1897-02-01
Granted: 1897-11-20
Abstract: 2657. Biheller, S., [Actiengesellschaft vorm. C. H. Stobwasser & Co.]. Feb. 1. Gas lamps or lanterns.-The lighting of incandescent and other lamps of the type shown, without removing the globe, is effected by the provision of a flap H in the casing, through which h a lighted taper may be passed. To permit of the globe being lowered without being detached, the globe holder E is arranged. at f to slide upon depending arms B from which the holder E can only be detached after the pins G have been withdrawn.
Patent GB-189707192-A (GB)
Title: Process and Apparatus for the Production of the Acetates of Lead, Copper, and the like.
Inventor: SCHMIDT ADOLF
Filed: 1897-03-19
Granted: 1897-06-05
Abstract: 7192. Schmidt, A. March 19. Acetates. - Acetates of lead, copper, or the like are produced by acting upon the metal with commercial oxygen and acetic acid under pressure and at a temperature of about 50‹-60‹C. In producing neutral acetate of lead, the chambers A and A', Fig. 1, are about half filled with lead in the form of shot or the like, 40 per cent. to 50 per cent. acetic acid is run into the chamber A' by the cock f, and the chamber is heated by steam passed into the lower compartment b. The acid is subsequently removed by the pump m to the chamber A and oxygen is admitted at about 2 atmos. pressure to the moist lead in the chamber A'. At intervals the acid is pumped from one vessel to the other, the oxygen passing in the opposite direction through the pipe l. Finally, the solution produced by this alternate treatment with acid and oxygen is run off by the outlet g. Neutral acetate of copper is produced in the same way. Sub-acetate of copper is made by treating copper plates of about 5 mm. thickness in the compartment a, Fig. 2, with the vapours from acetic acid, which is heated by steam in the compartment b, and with oxygen under pressure admitted through a regulating-valve p. After a time the plates are removed, the verdigris is scraped off, and the plates are put back for further treatment.
Patent GB-189712952-A (GB)
Title: Improvements in the Manufacture of Acetic Acid.
Inventor: SCOTT ERNEST GEORGE
Filed: 1897-05-25
Granted: 1898-04-30
Abstract: 12,952. Scott, E. G. May 25. Distilling acetic acid.-Crude acetic acid is freed from tar and concentrated by a process of distillation and fractional condensation in ovens. The crude acid is heated in a still a by means of a steam pipe b to a temperature of about 100‹ C., and the vapours are drawn off by a vacuum pump j through a series of condensers c<1>, c<2> .... c<10> into which they are delivered near the bottom by pipes d so as to bubble through the liquid already condensed therein. The condensers are fitted with a coil e through which steam or cold water may be passed for regulating the temperature. By this process the acid is condensed more rapidly than the steam, and when the acid in the first condenser is sufficiently strong, the contents are run off, and the liquid from the other condensers is run down a step by the pipes k<1> towards the first condenser. The last condenser c<10> is followed by a vessel g containing a hot strong solution of alkali, which takes up the remaining acid vapours, while the steam passes on to the jet condenser i.
Patent GB-189714773-A (GB)
Title: Improvements in the Pickers and Picking Mechanism of Weaving Looms.
Inventor: PARKER JAMES WILLIAM
Filed: 1897-06-18
Granted: 1898-04-23
Abstract: 14,773. Parker, J. W., and Bentley, J. June 18. Loom picking motions and mechanism.-In order to dispense with the picking - strap, the picking-stick F is preferably rounded at its end to pass through a hole G at the top of the picker G<2>, and is pivoted at E at a suitable distance behind the shuttle box C, to allow the required motion to be imparted to it by an arm H on the picking-shaft B connected to it by a link J.
Patent GB-189718455-A (GB)
Title: Combined Parting Rail and Weather Strip for Window Frames
Inventor: MERSEREAU CHARLES HENRY
Filed: 1897-08-09
Granted: 1897-09-25
Abstract: 18,455. Mersereau, C. H. Aug. 9. Draught-excluders; windows.-Rubber or elastic strips e, f are secured in grooves in the parting- bead d between the sashes b, c to prevent rattling and exclude draughts. The strips may be wedgeshaped as shown in Fig. 3 ; or they may be secured to the beads by wood or metal strips d<1>, Fig. 4, and screws d<2> ; or an elastic tube e<4>, Fig. 5, may be used. The strips may be made of the same length as the sashes, so as to come into action when the sashes are closed.
Patent GB-189721276-A (GB)
Title: Binding for Skirts and other Articles.
Inventor: DOTY LILLIAN FRANCIS
Filed: 1897-09-16
Granted: 1897-10-23
Abstract: 21,276. Doty, L. F. Sept 16. Dresses; b i n d i n g s.- Bindings or edgings for skirts and other articles are made of chamois skin dyed right through the material. The binding B may be folded upon itself and applied to an edge C of the skirt A, which is also folded upon itself as shown.
Patent GB-189722709-A (GB)
Title: Combined Wing-sails and Body Frame for use in the Propulsion of Cycles, Canoes, and the like.
Inventor: TURNER-TURNER JOHN
Filed: 1897-10-04
Granted: 1898-08-13
Abstract: 22,709. Turner-Turner, J. Oct. 4. Sails. - Relates to wing sails which may be attached to the person for the propulsion of canoes and the like. The main ribs of steel or whalebone &c. are made in two parts R', R<2> pivoted together at R, and any number of projecting ribs r are fixed to such main ribs and the wings covered with silk, canvas, &c. so as to form a sail S. The ribs R<1> pass through guides A, A fixed to the cross-rods f of the frame, and are connected to a base R'. The frame consists of bands F<1>, F<2>, which are crossed and pivoted at F, and the upper ends C, C take over each shoulder of the person and the lower ends C', C' are secured in front by a strap and buckle. Extensions r<1> of the ribs R<2> are connected to the frame by a flexible connection T. A spring A<1> normally holds the sail in a collapsed position. To open the sail, lifting-cords G, passing from the base R<3> over guides g, g to the front of the user, are pulled, and the ribs R' are raised and the connections T elevate the ribs R' and open the sail. The cords g, g are secured when the sail is opened, or may be wound on a reel provided with a stop motion. Auxiliary strips of elastic may be attached to the ribs and the frame to keep the sail in position when collapsed.
Patent GB-189724830-A (GB)
Title: Improvements in Railway Carriage and other Sash Windows.
Inventor: HILL EDWARD JACOB
Filed: 1897-10-26
Granted: 1898-06-04
Abstract: 24,830. Hill, E. J., and Hill, V. W. Oct. 26. Windows, sliding. Consists in hinging a flap B to the bottom of the sash A and in attaching the strap C to this flap, so that, when the sash is drawn up, the flap is pulled inwards and the sash is pushed outw a r d s over the fence rail. The flap B is provided with end tenons or end rollers, which run in the grooves E and keep the flap normally upright. When lowering the window sash, it is pulled inwards at the bottom by an additional strap I, described in Specification No. 29,490, A.D. 1897, or by a finger grip fixed to the bottom rail.
Patent GB-189725226-A (GB)
Title: A New or Improved Curtain Hook.
Inventor: HODGSON MARGARET
Filed: 1897-10-30
Granted: 1898-04-02
Abstract: 25,226. Hodgson, M. Oct. 30. Curtains, suspending.-Relates to a double cur t a i n hook, as shown.
Patent GB-189729712-A (GB)
Title: Improvements in or relating to Window Sashes and the like.
Inventor: REED JOHN HAWKES
Filed: 1897-12-15
Granted: 1898-10-15
Abstract: 29,712. Reed, J. H. Dec. 15. Windows.-The sashes A are hinged to guide blocks or plates C' so that they can be turned inwards for cleaning &c. The plates C<1> are arranged to slide in grooves in the pulley stile, and are retained in place by slotted metal plates or strips D'. At the opening side of the window, pins projecting from loose sliding stiles engage with bayonet-slots F<1> in the sash stiles. Each loose sliding stile is connected by a cord to a weight, and is detached from the sash by inserting a stop-pin in the frame above the sliding stile, and then raising the sash.
Patent GB-189801755-A (GB)
Title: Improvements relating to Railway Carriage Door Locks.
Inventor: THOMPSON CHARLES
Filed: 1898-01-22
Granted: 1898-08-13
Abstract: 1755. Thompson, C. Jan. 22. Locks and fastenings, railway-carriage door.-The doors are simultaneously locked by the starting of the train and unlocked by its coming to rest, the locking-bolts having spring ends to allow any door to be independently closed after the train has started. The bolts can be simultaneously locked by the guard &c. when required. The buffers b and draw-bars l are connected by rods and levers to side rods e on the carriage, suitable springs being interposed to take up excess motion, the arrangement being such that a sliding motion is given to the rods e to shoot the locking-bolts whenever the buffers are compressed or the draw-bars extended, the locking-bolts being operated by levers from the side rods. When the pressure is taken off, the bolts are retracted by the backward movement of the side rods due to springs g acting in casings h. A cam p on the side rod abuts against a cam q on the casing, so that, by giving the rod half a turn, it is moved longitudinally to lock the doors. This rotation may be effected from the guard's van by a hand-wheel and endles chain, the hand-wheel being held by a spring pin in either of the required positions. The rods are coupled together to transmit rotation by forming each rod with a square end e<x>, Fig. 7, to engage a square hole in the bell-mouthed end e<1> of the adjacent rod. This arrangement allows the rods to couple automatically when the carriages are pushed together, and permits of relative movement due to oscillation or passing round curves.
Patent GB-189813669-A (GB)
Title: Improvements connected with Drawing Easels.
Inventor: TORNAU NICOLAS DE
Filed: 1898-06-20
Granted: 1898-10-22
Abstract: 13,669. Tornau, N. de. June 20. Easels.-An appliance for tilting a painting, or the like, to a suitable angle upon an easel, consists of a rod I upon which are adjustable, by means of sleeves H<1>, H' and screws C<1>, C', two clips K<1>, K' fitted with springs D. One of the clips holds the painting B, and the other is attached to one leg S of the easel, as shown in Fig. 2. The clips may be lined internally with rubber, felt, or the like.
Patent GB-189813770-A (GB)
Title: New or Improved Fire-engine Operated by Means of a Petroleum-motor.
Inventor: GOLBY FREDERICK WILLIAM
Filed: 1898-06-21
Granted: 1899-05-13
Abstract: 13,770. Golby, F. W., [Porteu L., and Cambier, T.]. June 21. Motor road vehicles.-Relates to a fire-engine in which the pumps or the vehicle can be propelled by a petroleum motor. In plan, Fig. 2, the motor M has four cylinders working on to two cranks on the shaft A. The pumps P are worked through bevel gearing E and spur gearing e driving the pump crank shaft p. By means of the friction clutch K the pumps can be thrown in and out of gear. The road wheels R are driven by a pitch chain running on the sprocket-wheels C c. The shaft of the wheels c can be driven at two different speeds by cross belts and pulleys B, b, and D, d, b<1> and d' being loose pulleys. The pulleys G, g are driven by an open belt for reversing the carriage. The carriage frame is fitted with suitable seats and platforms and handles for driving and steering.
Patent GB-189814116-A (GB)
Title: Improvements in and relating to Children's Mail Carts and other Vehicles.
Inventor: GRIFFITHS WILLIAM
Filed: 1898-06-25
Granted: 1899-06-10
Abstract: 14,116. Griffiths, W., and McEwen, W. C. June 25. Seats and seat backs; aprons; children's mail carts. -Fig. 4 shows a mail cart with a fixed seat F, auxiliary seat C, and the well covered with a hinged plate E. When the seat C is pushed back, the rods a<5>, which are pivoted at a<6> and guided in grooves a<4>, assume the position shown in Fig. 3, while the hinged portion C' of the seat falls into a semi-vertical position, the sides C<4> fold inwards, and the seat back C<3> forms an apron for the occupant of the seat F.
Patent GB-189814296-A (GB)
Title: Improvements in the Construction of Tricycles and like Velocipedes.
Filed: 1898-06-28
Granted: 1899-04-22
Abstract: 1 4 , 2 9 6 . Marriotts' (Limited) and Spencer, J. D. June 28. Frames for central-gear tricycles &c. The front tube a and seat tube b are forked at their lower ends as shown, and two stays c are employed as shown, so as to leave space for the driving-chain, gear case, &c. The arrangement is applicable to ladies' and gentlemen's machines, and to the form of convertible described in Specification No. 6035, A.D. 1898.
Patent GB-189814411-A (GB)
Title: Improvements in Latrines.
Inventor: ADAMS MOSES JAMES
Filed: 1898-06-30
Granted: 1898-08-06
Abstract: 14,411. Adams, M. J. June 30. Latrines.-Hopper basins A are connected by junctions B directly to a common pipe C trapped at D. The basins are made to extend at the back so as to fill up the usual space found between each basin and the wall.
Patent GB-189826199-A (GB)
Title: Improvements in Surface Condensers.
Inventor: THOMPSON WILLIAM BRUCE
Filed: 1898-12-12
Granted: 1899-11-25
Abstract: 26,199. Thompson, W. B. Dec. 12. Condensers.-Surface condensers are made in two or more sections, through all of which the steam and water pass, in opposite directions. The one shown consists of two sections. Steam enters by the pipe 8, and is thrown by the baffle-plate 11 among the tubes. From the upper section the steam passes by a connection 7 to the lower one. Water of condensation passes by a pipe 10 from the upper section directly to the discharge pipe 9 leading to the air pump. The condensing-water is supplied by a pipe 5, and discharged by the pipe 6, as indicated by the arrows. The lower section can be used as a condenser for a winch or donkeyengine on board a ship in port, the valve 12 being closed.
Patent GB-189826352-A (GB)
Title: An Improved Folding Bicycle.
Inventor: TUERKHEIMER MOSE MAX
Filed: 1898-12-13
Granted: 1899-11-04
Abstract: 26,352. T³rkheimer, M. M. Dec. 13. Folding bicycles.-The upper and lower frame tubes 3, 4 are connected to the saddle pillar 5 by swivelling lugs 1, 2, so that the frame can be folded as shown in Fig. 2. The rear forks 8 are connected to a lug 6 fixed to the saddle pillar. The frame is locked in its extended or folded position by set-screws 9 bearing on a flat 5<a>, Fig. 4, of the saddle pillar, or by eccentric locking-devices. Suitable stops are provided to limit the folding movement. The handle-bar is arranged to swivel in any known way. Hooks and eyes 14, 15 for the attachment of carrying-straps may be fixed to the frame. Fig. 4 shows a section of the saddle pillar, which is constructed with a central feather.
Patent GB-189907105-A (GB)
Title: Improvements in Apparatus for Controlling the Reversing Mechanisms for Rudders or the like by Means of Electrical Waves.
Inventor: ORLING AXEL
Filed: 1899-04-04
Granted: 1900-04-04
Abstract: 7105. Orling, A., and Braunerhjelm, C. G. G. Feb. 24, [date applied for under Sec. 103 of Patents &c. Act, A.D. 1883]. Steering from outside vessel.-Relates to electromagnetic apparatus for controlling steering-gear. The magnet M' in circuit with the coherer x controls the local circuit containing the magnet M<2> and battery B<2>. The armature a<2> of the magnet M<2> frees the decohering hammer H, and, by means of a pawl st, rotates a commutator consisting of two crowns with alternating projections ; these are in circuit by means of brushes b, b<1>, b<2> with the battery B<3> and electromagnets M<3>, M<4>. The armature g of the magnets M<3>, M<4> operates the reversing valve of the steering gear.
Patent GB-189909266-A (GB)
Title: Improvements in the Manufacture of Barrels, Pipes or Cylinders and in Apparatus therefor.
Inventor: BARTELS JOHANN HEINRICH JULIUS
Filed: 1899-05-02
Granted: 1899-06-24
Abstract: 9266. Bartels, J. H. J. May 2. Wood pipes.-Relates to the manufacture of barrels, pipes, or cylinders of two or more layers of veneer. Fig. 2 shows the apparatus for compressing the veneer into a composite mantle against the outer cylinder H. The die or core A is divided into three or more separate segments wedge-shaped on the inside, and cones D are placed inside and coupled to the segments by dovetails. A thin plate may be placed over the surface of the segments at their intermeshing edges if desired. By rotating the right and left handed screw F the cones are caused to recede or approach one another, thus expanding or contracting the core and compressing the veneer. The sheet may be pressed hot or cold, by hand or by power.
Patent GB-189909516-A (GB)
Title: Improvements in Ladies' Hair-dressing Combs.
Inventor: BYSTERVELD HENRI GUILLAUME ANT
Filed: 1899-05-05
Granted: 1899-06-24
Abstract: 9516. Bysterveld, H. G. A. de. May 5. Combs, hair, for dressing ladies' hair are made with one or two rows of teeth at rightangles to the back, and are provided with a plain or toothed locking- bar.
Patent GB-189910963-A (GB)
Title: Improvements in Apparatus for the Production of Glass Articles.
Inventor: SIEVERT PAUL THEODOR
Filed: 1899-05-25
Granted: 1899-12-09
Abstract: 10,963. Sievert, P. T. May 25. Blowing.-Relates to methods of blowing glass articles of hollow form, such as lamp chimneys, bottles, tumblers, &c., the process employed being similar to those described in Specifications Nos. 2094 and 2679, A.D. 1899. Instead of providing the plate a, Fig. 1, on which the sheet e of molten glass rests, with a large number of openings for the passage of air, a single air-supply pipe b<1> is employed, or at most a small number of openings, and, to equalize the thickness of the glass throughout the blown article, the plate a is dished as shown. When tumblers &c. thickest at the base are to be blown, the plate a may be made still more concave. A ring d, adapted to open, encloses with the plate a a furrow m which fills with glass and serves to retain the edges of the article blown. The mould g may rest on the ring d ; if, however, it rests on the glass, its lower edges should be made thin enough to prevent excessive cooling, as shown in Fig. 7. Fig. 9 shows a modified form of the retaining-furrows m, and Fig. 14 shows the invention applied to the blowing of a series of lamp chimneys. When single articles are to be blown, the plate a may be arranged to rotate on ball bearings, the rotation of the article in the mould preventing the formation of seams. The plate a may be mounted on trunnions as shown in Fig. 17<a>; blowing is then effected in an inverted position as shown in Fig. 17, which illustrates the formation of a glass cylinder to be subsequently opened out into a sheet.
Patent GB-189918190-A (GB)
Title: Improvements in School Satchels.
Inventor: SCHLOERB HENRY
Filed: 1899-09-08
Granted: 1900-03-17
Abstract: 18,190. Schloerb, H. Feb. 8, [date applied for under Sec. 103 of Patents &c. Act, A.D. 1883]. Satchels.-A sheet of flexible material B is pasted or otherwise secured upon the back of a board A, the books are placed upon the board, and the overhanging parts of the flexible sheet are folded about them and secured by straps b, b<1> attached to the board, which is also provided with a handle C. Upon the back of the board is fixed a grooved strip D, which forms a receptacle for pencils and the like, and is provided with a hinged or sliding lid.