baber/WOPTO huggingface dataset:
Patent CR-20200607-A (CR)
Title: Immunotherapy against melanoma and other cancers
Inventor: WEINSCHENK TONI
IPC: C12N5/0783
Filed: 2017-04-13
Abstract: <p>The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor- associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.</p>
Patent EC-SP003834-A (EC)
Title: Oxazolidinonas que tienen la funcion de una sulfoximina
Inventor: HESTER JACKSON B
IPC: A61K31/44
Filed: 2000-12-20
Abstract: La presente invención provee compuestos de la fórmula I (gráfico), que tienen potente actividad contra las bacterias grampositivas y gramnegativas.
Patent EC-SP056204-A (EC)
Title: Mezclas fungicidas
Inventor: STIERL REINHARD
IPC: A01N43/54
Filed: 2005-12-07
Abstract: La presente invención se refiere a mezclas fungicidas, que contienen como componentes activos 1)	dimoxistrobina de la fórmula I, y2)	el compuesto de la fórmula II, en una cantidad sinergética activa, procedimientos para combatir hongos nocivos con mezclas del compuesto I con el compuesto II, el uso de los compuestos I y II para la obtención de tales mezclas, así como productos que contienen estas.
Patent EC-SP066278-A (EC)
Title: Pirimidinas 2-sustituidas
Inventor: STIERL REINHARD
IPC: C07D239/42
Filed: 2006-01-11
Abstract: La invención se refiere a pirimidinas 2-sustituidas de la fórmula I Ien la que el índice n y los sutituyentes R1 hasta R3, así como L tienen las definiciones indicadas en la descripción y R4	corresponde a una de las fórmulas donde Ra, X y Rb tienen las definiciones indicadas en la descripción;así como procedimientos para su obtención, productos pesticidas que las contienen y el uso de las mismas como pesticidas.
Patent EC-SP077233-A (EC)
Title: Moduladores del receptor de progesterona que comprenden los derivados del pirrol-oxindol y los usos de los mismos
Inventor: FENSOME ANDREW
IPC: A61K31/404
Filed: 2007-02-09
Abstract: Se proveen derivativos pirrolo-oxindol útiles como antagonistas del receptor de progesterona, y métodos para prepararlos. Se describen composiciones farmacéuticas que contienen estos derivativos, así como su uso en contracepción y condiciones relaciones con hormonas
Patent EC-SP910753-A (EC)
Title: Centro de validacion y facturacion de tarjetas de credito de telefonos publicos modulares
Inventor: IBANEZ PALOMEQUE FRANCISCO
IPC: G07F7/00
Filed: 1991-06-12
Abstract: Consiste en que el software incluído en el sistema con objeto de realizar las transacciones necesarias para validar las tarjetas de crédito utilizadas en los teléfonos públicos modulares, dialogando con la unidad de validación e identificación del teléfono público modular, así como está capacitado para gestionar la facturación de estas llamadas correspondientes a cada una de las entidades de crédito involucradas, permitiendo realizar la adaptación de un protocolo standard para la comunicación con los centros de gestión de las entidades crediticias y con el centro de gestión de telefónica en base a una estructura de mensaje definido.
Patent EC-SP941048-A (EC)
Inventor: MITCHELL JANE
IPC: A43B17/02
Filed: 1994-02-24
Abstract: An arch support is provided for treatment of problems arising from the displacement of the cuboid-navicular arch, the support comprising a base portion having a rear edge and a front edge, a top portion raised above the base, a first surface sloping upwardly and forwardly from the base rear edge to the top portion, and a second surface sloping downwardly and forwardly from the top portion to the base front edge, wherein the maximum depth of the arch support is in the region of the top portion adjacent the first surface for engaging the cuboid-navicular arch of the foot.
Patent EC-SP961643-A (EC)
Title: '2-(2-n-alcoxifenil-)-purin-6 onas- 9 sustituidas lea 30701- ec
Inventor: PERZBORN ELISABETH
IPC: A61K31/52
Filed: 1996-01-19
Abstract: Se refieren a la preparación de 2-(2-n-alcoxifenil) purin-6-onas 9- sustituidas de la fórmula general (I). Las mismas que se preparan ciclando los imidazoles correspondientemente sustituidas y se derivatizan las purinas así obtenidas. La 2--(2-n-alcoxifenil) purin-6-onas 9-sustituidas se pueden utilizar como principios activos en medicamentos, en especial en medicamentos para el tratamiento de inflamaciones, enfermedades tromboembólicas, así como enfermedades cardíacas y circulatorias.
Patent FI-20031888-A (FI)
Inventor: OSHLACK BENJAMIN
IPC: A61K47/44
Filed: 2003-12-22
Abstract: (A) Controlled release oxycodone formulation for oral admin. to human patients, comprises (i) 10-40mg oxycodone or its salt, the formulation providing a mean max. plasma conc. of oxycodone of 6-60 ng/ml from a mean of 2-4.5 hrs.. After admin., and a mean min. plasma conc. of 3-30 ng/ml from a mean of 10-14 hrs. after repeated admin. every 12 hrs. through steady state conditions. (ii) 10-160 mg oxycodone or its salt, the formulation providing a mean max. plasma conc. of oxycodone of 6-240 ng/ml from a mean of 2-4.5 hrs. after admin., and a mean min. plasma conc. from 3-120 ng/ml from a mean of 10-14 hrs. after repeated admin. every 12 hrs. through steady-state conditions. (B) Also claimed is a solid controlled release oral dosage form comprising (i) oxycodone or its salt in amt. of 10-160 mg; a controlled release matrix selected from hydrophilic hydrophobic polymers, digestible opt. substd. 8-50C hydrocarbons, and/or polyalkylene glycols; and a diluent; wherein the compsn. provides a mean max. plasma conc. of oxycodone of 6-240 ng/ml from a mean of 2-4.5 hrs. after admin, and mean min. plasma conc. of 3-120 ng/ml from a mean of 10-14 hrs. after repeated admin. every 12 hrs. through steady-state conditions; or (ii) an analgesically effective amt. of spheroids comprising oxycodone or its salt and either a spheronising agent or an acrylic polymer or copolymer, such that the total dosage of oxycodone in the dosage form is 10-160 mg; a film coating which controls the release of the oxycodone or its salt at a controlled rate in an aq. medium, wherein the compsn. provides an in vitro dissolution rate of the dosage form.
Patent GB-1047411-A (GB)
IPC: H02M7/10
Abstract: 1,047,411. Silicon rectifiers; circuit assemblies. WESTINGHOUSE ELECTRIC CORPORATION. Feb. 3, 1965 [Feb. 27, 1964], No. 4694/65. Headings H1K and H1R. [Also in Division H2] Series connected rectifying elements 70 in a high voltage rectifier circuit are shunted by capacitors and resistors and encapsulated in a fully cured epoxy resin through which the external connecting leads 110, 130 pass. The resin is coarsely filled with thermally conductive particles. The assembly is enclosed in a surrounding outer case of cured, thermally conductive resin having apertures through which the leads pass. The Specification lists suitable resins and fillers and discusses the cooling of the assembly.
Patent GB-1051727-A (GB)
IPC: C25D1/10
Abstract: 1,051,727. Printing-surfaces. ROTARY PLATES Ltd. July 9, 1964 [Aug. 29, 1963], No. 34289/63. Heading B6C. [Also in Division C7] An electrotype is produced by forming a first backing layer of lead, a lead alloy or a mixture of metals which can be planed, shaved or bored by standard electrotype equipment on an electro-deposited shell, and electrolytically depositing on the first backing layer a second backing layer of a metal or alloy which is more rigid than the same thickness of lead, e.g. of copper or nickel. A third backing layer of metal which can be planed, bored or shaved, e.g. lead or a lead alloy, may be applied by electrodeposition. Typically an electrodeposited acid copper shell of thickness 10 mils. formed on a flat silvered plastic mould adhesively secured to a glass plate is removed from the mould, a 5 mils. foil of lead-tin alloy is applied to the back of the shell and heated to 200‹ C. to fill the depressions, and the shell is then lacquered on its printing face and electroplated with a lead-tin alloy first backing layer to a deposit thickness of 45 mils, followed by planing to give an overall thickness of 49 mils. Acid copper to a thickness of 10 mils was then electrodeposited as the second backing layer followed by a lead-tin electrodeposit of 8 mils. thickness, whereafter this third backing layer was planed to give an overall thickness of 64 mils. In an alternative procedure for a curved electrotype, a thermoplastic mould is immersed in hot water and pressed into a former of the desired curvature, silvered, and a 10 mils. acid copper shell deposited on it, the copper shell is removed and lacquered on its printing face, electroplated with lead-tin to a thickness of 35 mils, bored to give an overall thickness of 40 mils, flash-plated with cyanide copper, plated with acid copper to 20 mils. thickness, plated with lead-tin alloy to a thickness of 8 mils. and finally bored to an overall thickness of 64 mils. The lead-tin alloy electroplating bath is a fluoborate bath containing glue and #-naphthol. Reference is made to employing optionally tin-lead alloys containing one or more of antimony, cadmium, copper, and nickel.
Patent GB-1225830-A (GB)
IPC: A61K31/215
Filed: 1968-12-31
Abstract: 1,225,830. Anti-psoriasis compositions. CIBA Ltd. 31 Dec., 1968 [8 Jan., 1968], No. 61909/ 68. Heading A5B. Pharmaceutical preparations, e.g. ointments, creams, pastes, foams, lotions and aerosol sprays, for the treatment of psoriasis, contain a dermatologically active steroid, and a triester of dithranol (1,8,9-trihydroxyanthracene) with a C 1-6  alkanoic acid unsubstituted or substituted by halogen and/or C 1-6  alkyl, in admixture or conjunction with a pharmaceutically suitable carrier. Triacetyldithranol is preferred. Suitable steroids include hydrocortisone, prednisolone, fluocortolone, fluorohydrocortisone, dexamethasone, betamethasone, triamcinoline and its acetonide, fluorometholone, 3, 20-dioxo- 6-fluoro-11, 16, 17, 21-tetrahydroxypregna-#<SP>4</SP>- en-16, 17-acetonide, fluocinolone acetonide and flumethasone or their esters with alkanecarboxylic acids or with inorganic acids, e.g. phosphoric or sulpuric acid, such as flumethasone pivalate. The preparations may also contain a keratolytic, e.g. salicyclic acid, antibiotics, antimycotics or antiseptics.
Patent GB-1226124-A (GB)
IPC: G01R25/00
Filed: 1968-04-04
Abstract: 1,226,124. Analogue / digital converters. FUNKWERK ERFURT. VEB. 4 April, 1968, No. 16253/68. Heading G4H. To measure the time interval between two signals on leads 1, 2 (Fig. 2) the first signal switches a multivibrator 3 so that a gate 16 (Fig. 2) is enabled to pass clock pulses to a counter 10, the second signal switching a multivibrator 13 which closes the gate to terminate the count. In the described embodiment for measuring the phase difference between two A.C. signals, multivibrators 3, 13 are first set to their rest position, i.e. with output signals at U 7 , U 15 . A pulse at input 1 representing the first positive-going zero crossing of the first signal 1 switches multivibrator 3 so that gates 17 are enabled to allow clock pulses to pass to counter 10 until a positive-going zero crossing of the second signal switches multivibrator 13 and the gates 17 are closed. The next pulse at input 1 enables gates 18 so that pulses are again accumulated in counter 10 until multivibrator 13 is switched by a signal at input 2. This process may be repeated over any number of cycles of the A.C. signals. A gate 21 prevents the multivibrators 3, 13 being set to their rest position between positive zero crossings of the first and second signals.
Patent GB-1230051-A (GB)
IPC: F28D15/04
Filed: 1970-01-05
Abstract: 1,230,051. Heat transfer devices. UNITED STATES ATOMIC ENERGY COMMISSION. 5 Jan., 1970 [22 Jan., 1969], No. 365/70. Heading F4U.  A heat transfer device which operates to maintain a heat generating body e.g. a fuel cell 1, at a constant temperature comprises heat pipes 2, 5 having a common wall section 10 between them through which heat transported from the body 1 by means of a condensable vapour, inert gas, and capillary lining (not shown), in the heat pipe 2 passes to be radiated to ambient atmosphere by the similar second heat pipe 5 at surface 7. The vapour may be water or 1,1,1,2- tetrachloroethane and one or more heat pipes may be connected to the second heat pipe which may be of circular form and the next succeeding pipe by a common wall section in chain fashion.
Patent GB-1231302-A (GB)
IPC: A21B1/44
Filed: 1969-07-15
Abstract: 1,231,302. Bakers' ovens. M. E. TILLANDER and A. B. PERSSON [trading as TI-PE ELMEKO, TILLANDER AND PERSSON]. 15 July, 1969 [31 July, 1968], No. 35481/69. Heading A2A. A bakers' or similar oven of the kind having an oven chamber adapted to receive a rack 10 loaded with goods to be treated, and having at the top of the oven a rotatable or reciprocable driver member adapted to be releasably engaged by the rack to impart to the latter a rotary or reciprocatory motion, includes an arrangement whereby the driver member is shiftable between a lower position for bringing the rack and driver member into engagement with each other, with the rack still supported by the floor of the oven chamber, and an upper position in which the rack is freely suspended from the driver member. A rotatable driver member 14 is shown, rotation being effected by a shaft 17 which is driven via a pulley 23 and is also axially slidable, A cylindrical cam 22 is fixed to the top plate 25 of the oven and is engaged by rollers carried by a collar 21 which is rotatable about the axis of the shaft 17 by a lever arm 27 connected as by a link with the door of the oven. The arrangement is such that when the door is opened the rollers carried by collar 21 rest in two low cam segments of the cam 22 and the, driver member is in its lower (chain-line) position which allows a rack to be wheeled into the oven to position engagement flanges 16 on the rack just above flanges 15 on the driver member. The door is now closed, causing rotation of the collar 21 whose rollers consequently ride up sloping cam segments of the cam 22 to high cam segments, causing the pulley 23 and shaft 17 to be raised, so that the driver member is lifted to its upper (full-line) position during which the flanges 15 and 16 engage and the rack 10 is thereby lifted off the oven floor. When the door is nearly closed, it actuates a switch which energizes a motor driving the pulley 23, so that the rack 10 is rotated until the door is reopened, whereupon the driver member is lowered to allow the rack 10 to be wheeled out of the oven chamber. Instead of a cylindrical cam 22 and rotatable collar 21, a toggle linkage 32, 34, Fig. 5, may be used, the pivotal connection 38 of the linkage being connected to the oven door by a link 28A whereby upon closure of the oven door forces apart the ends of the toggle links which are pivoted at 33, 35 to collars 21A, 36, the latter of which is supported on the top plate 25 of the oven by a thrust bearing 37, while a second thrust bearing 24 is interposed between the collar 21A and pulley 23. Instead of a toggle linkage, a single link, having its lower end provided with a roller which rolls on the top plate 25 of the oven, may be used (Fig. 7, not shown). The oven is provided with a fan 11 for circulating hot air around and through the oven chamber as indicated by the arrows (Fig. 1).
Patent GB-1231389-A (GB)
IPC: F02M41/14
Filed: 1967-08-24
Abstract: 1,231,389. Reciprocating pumps. C. A. V. Ltd. Aug.6, 1968, [Aug.24, 1967], No.39038/67. Heading F1A. [Also in Division G3] ] In a rotary distributor type fuel injection pump a valve body 30 in the inlet port is provided with a groove 31 and passages 50, 51, which communicate with a fuel inlet 32 during normal running and starting of the engine respectively; the passages 50, 51 are prevented from connecting with inlet 32 during normal running by a stop 61 acting against a cam surface 60 on a radial arm carried by member 30. The throttle operation is described in Specification 1, 171, 791. Axial and angular movements of the valve body are controlled by feed pump pressure and a governor respectively. The valve body may be held in the excess fuel position by a pin engaging the radial arm of body 30.
Patent GB-1232910-A (GB)
IPC: A01C15/00
Filed: 1969-11-12
Abstract: 1,232,910. Hopper spreader. NODET-GOUGIS. 12 Nov., 1969 [14 Nov., 1968], No. 55319/69. Heading A1D. [Also in Division B8] A hopper spreader for powdered or granulated material comprises an auxiliary hopper 3 which supplies material to the spreader hopper 1 by means of an endless belt elevator 2 which forms one wall of the auxiliary hopper 3. The endless belt elevator 2 which is driven from a tractor engine or P.T.O. through a shaft 4 and gear drive 5 raises material from the auxiliary hopper 3 between transverse rods 2<SP>1</SP> and a sheet 11, the belt 2 being driven rapidly enough for the kinetic energy imparted to the material to be sufficient to cause projection of the material from a baffle-forming end 12 towards the centre of the spreader hopper 1.
Patent GB-1238713-A (GB)
IPC: F24D3/00
Filed: 1968-05-22
Abstract: 1,238,713. Water heating installations. F. S. HOWARD. 21 Aug., 1969 [22 May, 1968], No. 24512/68. Heading F4A. A heating installation circuit including a water heater 11, a pump 21, and a closed expansion vessel 13, is connected through a non-return valve 28 to a water cistern, and an air vent valve 29 is located at the uppermost part of the circuit. The heater 11 which may be powered by gas, oil or electricity is connected through flow and return pipes 12, 20 and manifolds 14, 14<SP>1</SP> to a hot water circuit including a regulating valve 30 to control the flow of water in a heating element 16 inserted in a hot water tank 17 fitted with a thermostat controlling a solenoid actuated valve in the circuit. A radiator circuit 151, 19<SP>1</SP> includes a radiator 18, and other radiator circuits are indicated by the arrow A. The pump 21 is fitted in the return pipe 20 between isolating valves 22, and the expansion vessel 13 is provided with a thermometer 23, automatic air vent 24 and safety valve 25. Alternatively the pump may be fitted in the flow pipe 12, and the expansion vessel in the return pipe 20. A pipe 26 brings cold water from the cistern to the tank 17 and through an isolating valve 27 to the heating circuit. In another embodiment the heating system can be shut off by a closing valve (33), Fig. 2 (not shown), when not required. In a further modification, Fig. 3 (not shown), a ball stop cock (27<SP>1</SP>) replaces the stop cock 27 and a regulating valve (34) is placed in the circuit adjacent the air vent valve.
Patent GB-1238714-A (GB)
IPC: D03D35/00
Filed: 1968-06-18
Abstract: 1,238,714. Forming selvedges in shuttleless looms. CROMPTON & KNOWLES CORP. 18 June, 1968 [30 June, 1967], No. 29023/68. Headings DIE and D1K. In a selvedge of the kind formed by knitting a selvedge thread through the looped ends of double picks inserted by a weft inserting needle, two selvedge threads are used alternately whereby the knitted chain is less likely to run if one thread breaks. The two selvedge threads are presented to the knitting needle in turn by cam-operated eyelets. In the case of fabric woven with an elastic warp, an extra selvedge thread 114 (or as shown, two extra threads 114, 118), may be knitted occasionally and then floated whilst the two normal selvedge threads are being used; when the fabric relaxes, the extra threads project from the edge of as decorative loops.
Patent GB-1250302-A (GB)
IPC: H02K5/22
Filed: 1970-01-26
Abstract: 1,250,302. Two-part couplings. G.I.LOCKE. 26 Jan., 1970 [18 March, 1969], No. 3730/70. Heading H2E. A connecting device for a three-phase motor 12 operable at either of two voltages comprises a pair of jumper caps, 34, 36 for alternative cooperation with a plug member 30. The plug member 30 has a shell 66 screwed on to the housing 20 of the motor 12, containing two dielectric discs 54, 58 held in by a plate 62 and a lip 70 on the shell 66 respectively. Nine leads, L1 . . . L 9  from the motor pass through a hole 64 in the plate 62 and are each crimped to one of nine plug contacts 42 held in the dielectric discs 54, 58. For operation of the motor at its lower voltage a low-voltage jumper-cap 34, Figs. 1, 3, is provided comprising an insulating body 80 containing nine sockets 82 acting as contacts LT 1  . . . LT 9  for connection to plug contacts 42 in member 30 which act as contacts T 1  ... T 9 . Three conductors LV 1  . . LV 3  from the lowvoltage three-phase power supply are retained in contacts LT 1  . . . LT 3  by screws 96. As seen in Fig. 3 internal connections are made within jumper cap 34 connecting contacts LT 1  and LT 7 ; LT 2  and LT 8 ; LT 3  and LT 9 ; LT 4 , LT 5  and LT 6 . Contacts T 5  and LT 5  are offset from the square pattern formed by the other contacts to provide polarization. For operation of the motor at its higher voltage a high-voltage jumper cap, 36, Fig. 4 is provided which is similar to cap 34, comprising an insulating body 90 containing contacts HT 1 . . . HT 9 . The three high-voltage power supply conductors HV1 . . . HV 3  are connected to contacts HT 1  . . . HT 3  by screws 102. Internal connections are made connecting contacts HT 4  and HT 7 ; HT 5  and HT 8 ; HT 6  and HT 9 , and contact HT 5  is offset for connection to contact T 5 . The plug member 30 may be removed from the motor 12 for transport.
Patent GB-1251831-A (GB)
IPC: C07C45/34
Filed: 1968-01-13
Abstract: 1,251,831. Unsaturated esters and aldehydes. C. G. M. SLESSER and A. R. CUMMING. 9 Jan., 1969 [13 Jan., 1968], No. 2035/68. Heading C2C. α,#-Unsaturated esters of monocarboxylic acids, 1,2-glycols, hydroxy ethers, aldehydes and epoxide are prepared by passing a gaseous olefin and oxygen simultaneously into a liquid medium selected from water, alcohols and liquid monocarboxylic acids, said liquid medium containing a catalyst in the form of palladium-containing particles so that the olefin and oxygen react together to form in solution in the liquid medium an epoxide at least a portion of which then reacts with the liquid medium to form at least one of said organic compounds, and separating one of the said organic compounds as a major product.