baber/WOPTO huggingface dataset:
Patent EP-1232260-B1 (EP)
Inventor: BRINKMANN ULRICH
IPC: C12Q1/68
Filed: 2000-07-28
Granted: 2007-09-19
Abstract: Described are general means and methods of diagnosing and treating the phenotypic spectrum as well as the overlapping clinical characteristics with several forms of inherited abnormal expression and/or function of the Multi Drug Resistance-1 (MDR-1) gene. In particular, polynucleotides of molecular variant MDR-1 genes which, for example, are associated with unsufficient and/or altered uptake of drugs by a target cell, and vectors comprising such polynucleotides are provided. Furthermore, host cells comprising such polynucleotides or vectors and their use for the production of variant MDR-1 proteins are described. In addition, variant MDR-1 proteins and antibodies specifically recognizing such proteins as well as concerns transgenic non-human animals comprising the above-described polynucleotide or vectors are provided. Described are also methods for identifying and obtaining inhibitors for therapy of disorders related to the malfunction of the MDR-1 gene as well as methods of diagnosing the status of such disorders. Pharmaceutical and diagnostic compositions comprising the above-described polynucleotides, vectors, proteins, antibodies and inhibitors by the above-described method are provided. Said compositions are particularly useful for diagnosing and treating various diseases with drugs that are substrates, inhibitors or modulators of the MDR-1 gene product.
Patent EP-1228477-B1 (EP)
Inventor: LLOYD TIM
IPC: G06K7/00
Filed: 2000-11-10
Granted: 2004-03-31
Abstract: A connector device for connecting a smart card to a computer comprises a receptacle having an upwardly facing opening for receiving the card. The receptacle contains spring contacts which establish electrical contact with the card contacts, and which serve to connect the card contacts to the computer, and is provided with a projection adjacent the opening to facilitate one-handed withdrawal of the card from the receptacle.
Patent EP-1139024-B1 (EP)
Inventor: ZERRES MANFRED
IPC: F24B1/06
Filed: 2001-02-05
Granted: 2004-06-30
Abstract: The assembly group for securing tiles on the metallic housing of a ready-made stove involves the tiles on lateral surfaces being alternately formed with tongues and grooves. Stirrups (3) are provided fixable to the metallic housing (1), spaced apart by a distance corresponding to the dimension of the tiles (4-6), for which a securable tab (9) is insertable between two adjacent tiles. The stirrups have a U-shaped cross-section and fixture noses running parallel to the rib connect to the free ends of the legs (3a). The tab is L-shaped and has a leg (9a) inserted in the stirrup and a further leg (9b) securable between two adjacent tiles.
Patent EP-1157611-B1 (EP)
Inventor: KAWAGUCHI MASAHIRO
IPC: A01M29/16
Filed: 2001-03-09
Granted: 2004-11-17
Abstract: A solar-powered ultrasonic animal repeller is disclosed for outputting an ultrasonic wave when an entry of a small animal into a predetermined area is detected. The ultrasonic animal repeller (1; 1A) is powered by an electric power circuit including at least one solar battery (15) mounted on a roof of the ultrasonic animal repeller (1; 1A), and a charging circuit (16) for charging an electric power generated by the solar battery (15). <IMAGE>
Patent EP-1245218-B1 (EP)
Inventor: SHOHER ITZHAK DR
IPC: A61C5/08
Filed: 2001-03-27
Granted: 2007-09-26
Abstract: A bonding material for joining a polymeric veneering material or porcelain ceramic to a metal framework of a dental restoration or dental prothesis before sintering the porcelain at a suitable temperature to form a clinically unbreakable structure. The bonding material is composed of finely divided metal particles including at least 50% gold or a gold alloy as its major constituent and finely divided particles of a carbonaceous material preferably of activated carbon.
Patent EP-1307036-B1 (EP)
Inventor: HELLWIG KARL
IPC: H04L29/06
Filed: 2001-10-29
Granted: 2006-03-01
Abstract: The present invention relates generally to interception communications in a telephone network, and more, specifically to intercepting communications in compressed mode, i.e. compressed voice frames are overlaid on a PCM stream. This object is achieved by a network node in a telephone system with at least one monitoring apparatus for monitoring payload data exchanged between at least two subscribers wherein the network node sends information on the codec type that has been selected by said at least two subscribers for their call to the monitoring apparatus and that a copy of the payload data is send unmodified to the monitoring apparatus. In one alternative, the codec type is limited by the monitoring apparatus to those codec types which the monitoring apparatus supports.
Patent EP-1215141-B1 (EP)
Inventor: BONNET HENRI
IPC: B65G15/06
Filed: 1998-01-06
Granted: 2005-03-30
Abstract: An automated conveyor sortation and item (20) discharge system (10) for sorting items of varying sizes and weights to designated output destinations along a conveyor. A serpentine configuration is provided by use of a continuous notched conveyor belt (70) layer, which can have no discharge capabilities, or can include. <IMAGE>
Patent EP-1128692-B1 (EP)
Inventor: SUONPERA ALLAN
IPC: H04Q7/32
Filed: 2001-02-20
Granted: 2005-05-04
Abstract: Personalised information is transferred from a first hand portable phone having a first memory means for storing said personalised information to a second hand portable phone having a second memory means for storing said personalised information. A connection between said first hand portable phone and a computer on which a data transfer application is running is established. The data transfer application on said computer is controlled to read said personalised information from said first memory means to store the personalised information in said first hand portable phone in memory means associated with said data transfer application in said computer. Then a connection between said second hand portable phone and said computer on which said data transfer application is running is established. The data transfer application on said computer is controlled to write said personalised information from said memory means associated with said data transfer application into said second memory means for storing said personalised information in said second hand portable phone. The user is allowed to individually select the type of personalised information to be written into said second memory means prior to the initialising of the data transfer. <IMAGE>
Patent EP-1209516-B1 (EP)
Inventor: GOUGH KEITH ADRIAN
IPC: G03B15/00
Filed: 2001-11-13
Granted: 2004-10-20
Abstract: A camera (10) having a housing (11) mounted on a wall bracket (9) via an upright stem (12) and ball joint (13, 14). The bracket (9) has an aperture (16) such that an electrical cable connection to the camera may include a four-terminal jack plug (17) which passes upwardly through the aperture (16), ball (13), stem(12) and housing (11) into a jack socket therewithin. Thus, the electrical connection is readily removed by withdrawing the jack plug (17), and any rainwater is prevented from entering the jack socket within the housing (11) by way of the downwardly opening bore (15) aligned therewith. <IMAGE>
Patent EP-1317107-B1 (EP)
Inventor: BATEMAN DAVID
IPC: H04J11/00
Filed: 2001-11-30
Granted: 2005-08-03
Abstract: In an orthogonal frequency division multiplex communication system, for example a HIPERLAN/2 system, power amplifiers (224) of mobile terminals (4, 6) are switched off when not in use, and then switched on again when a signal transmission is to be made. This conserves power, but introduces a power amplifier transient (315). An access point (2), i.e. a type of base station, compensates for these power amplifier transients (315) using a simple scalar constant gain transient correction, over a full OFDM symbol (or a plurality of OFDM symbols). The correction is updated on an OFDM symbol by symbol basis (or plurality of symbols by plurality of symbols basis). <IMAGE>
Patent EP-1219866-B1 (EP)
Inventor: DAMEY WALTER
IPC: F16H59/70
Filed: 2001-12-20
Granted: 2004-03-17
Abstract: The neutral position sensor for a motor vehicle gear lever (1) has an infra-red emitter (4) and a receiver (6) for the light beam. the emitter and receiver are positioned so that when the gear lever is in the neutral position, the beam is not interrupted, but it is when the lever is in a selection position. The infra-red receiver is connected to a display for the driver to indicate the position of the lever.
Patent EP-1257217-B1 (EP)
Inventor: CRAGG ANDREW H
IPC: A61F2/30
Filed: 2001-02-14
Granted: 2008-01-09
Abstract: Methods for correcting a deformity in the spine by forming a trans-sacral axial instrumentation/fusion axial bore through vertebral bodies in general alignment with a visualized, anterior axial instrumentation/fusion line in a minimally invasive, low trauma, manner and providing a therapy to the spine employing the axial bore. Curved or relatively straight anterior axial bores are formed from the anterior starting positions. The therapies performed through the axial bores include discoscopy, full and partial discectomy, vertebroplasty, balloon-assisted vertebroplasty, drug delivery, electrical stimulation and various forms of spinal disc cavity augmentation, spinal disc replacement, fusion of spinal motion segments and implantation of radioactive seeds. Axial spinal implants and bone growth materials can be placed into single or multiple parallel or diverging axial bores to fuse two or more vertebrae, or distract or shock absorb two or more vertebrae.
Patent EP-1263698-B1 (EP)
Inventor: MELNICHUK LARRY JACK
IPC: C07C47/052
Filed: 2001-03-06
Granted: 2008-05-21
Abstract: A process for the production of oxygenated C2 hydrocarbons from cellulose is disclosed. The input cellulose waste is gasified using steam in the absence of air and the primary gaseous products of carbon monoxide and hydrogen are subjected to heat, pressure, and catalysts to form methyl alcohol. Carbon monoxide is added to the methyl alcohol and further subjected to heat, pressure and catalysts to form acetic acid. The acetic acid is purified using a distillation tower, and removed for sale. Output production is increased by adding further carbon monoxide and hydrogen from burners used to heat the gasifiers. Further carbon monoxide and hydrogen are also produced by steam gasification of the carbon residue to promote a water/gas shift. These gases are fed into the gas stream produced by the gasification of cellulose, and provide more feedstock for the reactions. The three input gas streams arising from: 1) the steam gasification of cellulose; 2) the water/gas shift in the carbon reactor; and 3) the sub-stoichiometic oxygen burning of input burner gas to heat both retorts, maximize the output chemical production while reducing the consumption of energy needed for processing the cellulose and the carbon.
Patent EP-1268073-B1 (EP)
Inventor: WHETTINGSTEEL STEPHEN
IPC: B02C19/00
Filed: 2001-03-20
Granted: 2008-09-03
Abstract: Apparatus ( 2 ) for crushing glass or ceramic material, which apparatus ( 2 ) comprises a rotor ( 4 ), rotor blades ( 6 ) on the rotor ( 4 ), at least one stationary blade ( 8 ) which cooperates in use with the rotor blades ( 6 ) as the rotor ( 4 ) rotates, and a chamber ( 16 ) for receiving crushed glass or ceramic material ( 18 ), the apparatus ( 2 ) being such that the rotor ( 4 ) is upstream of the chamber ( 16 ), the glass or ceramic material ( 18 ) is first broken into fragments ( 20 ) on impact with the rotor ( 4 ), the fragments ( 20 ) are reduced in size and formed into cullet ( 22 ) by passing through a gap ( 24 ) between the rotor blades ( 6 ) and the stationary blade ( 8 ), and the action of the rotor blades ( 6 ) and the stationary blade ( 8 ) causes the cullet ( 22 ) to be such that it will not cut, is safe for handling, and is suitable for further use without further processing.
Patent EP-1295064-B1 (EP)
Inventor: RUTTER CHRISTOPHER C
IPC: B65B39/00
Filed: 2001-04-10
Granted: 2005-09-21
Abstract: A spout for a flexible bag adapted to hold a liquid, the spout adapted for coupling with a connector having a rotatable spout adapter with an internal thread. The spout has a substantially cylindrical body with an outer surface, a spout opening, and a spout axis. The spout further has at least one flexible tab attached to and protruding radially distal from the outer surface of the cylindrical body of the spout. The tab has a top side that is substantially perpendicular to the spout axis, a bottom side opposing the top side, and a leading edge for engaging the thread. Additionally, the spout, has an undeformed tab length that typically deforms upon engaging the internal thread of the spout adapter.
Patent EP-1285023-B1 (EP)
Inventor: NICOLA THOMAS
IPC: B32B27/32
Filed: 2001-03-16
Granted: 2010-12-29
Abstract: The invention relates to an elastic, substantially non-stretched film produced from olefinic materials that is completely free of PVC and that is yet adapted to the requirements of a film, such as a film for medical purposes, for example for heat sterilization. The inventive film has elastic properties up to a certain point that depend on the film's thickness, that means no permanent deformation can be observed. When the tensile stress is further increased, the film is deformed, that is it shows a plastic behavior until it finally tears or breaks. The transition is fluid since, unlike conventional films, the inventive film has no negative increase in the yield point. The increase in the yield point is >=0. The invention further relates to the use of the inventive films, for example in the field of medical engineering, and to bags for medical purposes that comprise at least one film according to the invention.
Patent EP-1286827-B1 (EP)
Inventor: ROBERTS CLARK A
IPC: B29D30/24
Filed: 2001-05-18
Granted: 2006-03-08
Abstract: A rotatable drum useful in the manufacture of vehicle tires. A plurality of segments collectively define the outer circumferential surface of the drum. These segments are divided into two sets, one set being disposed on each of the opposite sides of a transverse center plane of the drum, the center plane being oriented normal to the rotational axis of the drum. The two sets of segments are mounted for selective positioning thereof axially of the drum from a location external of the drum to adjust the overall working width of the drum. Further, the segments are selectively positionable between expanded positions radially of the rotational axis of the drum to provide a relatively continuous circumferential outer surface of the drum for the layup of a tire carcass thereon, and collapsed positions radially of the drum to permit the removal of a formed toroidal carcass from the drum. Movement of the plurality of segments of each of the two sets of segments radially of the rotational axis of the drum is effected by "slaving" the two sets of segments off a central mechanism which controls the radial positions of all the segments simultaneously and equidistantly from the rotational axis of the drum, while further providing for axial movement of the two sets of segments relative to one another while the segments are positioned at any given radial location of the segments.
Patent EP-1283766-B1 (EP)
Inventor: SCHNEIDER FRITZ
IPC: B27N1/00
Filed: 2001-05-18
Granted: 2005-08-03
Abstract: Wood fibres (2) which are used in the production of fibreboard are supplied from a metering device (1) through a supply chute (7) to a disintegration roller (12) comprising a large number of spikes (13) on its surface. The disintegration roller (12) rotates at high speed, in such a way that the spikes (13) deflect the fibres (6) hitting the disintegration roller (12). The fibres are entrained (6) by the spikes (13) and fed through a chute section (17) formed by a subsection (15) of the roller periphery and a wall (16) lying opposite the latter, to an outlet opening (18) of the chute section. Either a moulding belt (19) of a moulding machine is located beneath the outlet opening (18), or the fibres (6) pass from the outlet opening (18) into the air channel of an air fibre-separator. The disintegration roller (12) disintegrates irregularities in a fibre stream (6), e.g. fibre bundles, or drops of condensed water.
Patent EP-1301847-B1 (EP)
Inventor: BAKKER WILLEM HENDRIK
IPC: A47B21/03
Filed: 2001-07-13
Granted: 2004-03-17
Abstract: Support for a portable computer having a display flap which is pivotable relative to a keyboard member. For supporting the keyboard member, there is provided a support structure. A bearing structure projects downwards from the support structure for keeping the display of the computer at a distance above a face on which the support stands. A document support supports a document extending above the support structure. A display of a portable computer can thereby be placed at an ergonomically favorable height above the worktop, while loss of space for documents is limited and documents to be consulted can be supported at an ergonomically favorable height above the worktop. A method for the use of a portable computer is likewise described.
Patent EP-1313396-B1 (EP)
Inventor: NAGAR RON
IPC: A61B10/00
Filed: 2001-08-09
Granted: 2006-06-28
Abstract: A method for assaying a component of a localized region of interest in a body comprising: illuminating the region with at least one pulse of radiation having a wavelength at which the radiation is absorbed by the component to generate a change in an acoustic property of the region; transmitting ultrasound so that it is incident on the region; measuring at least one effect of the change on the incident ultrasound; using the measured at least one effect to determine an absorption coefficient for the radiation in the region; and using the determined absorption coefficient to determine concentration of the component in the region.
Patent EP-1320448-B1 (EP)
Inventor: BROGARDH TORGNY
IPC: F16H21/54
Filed: 2001-08-20
Granted: 2008-01-23
Abstract: The invention includes a manipulator to move an object with at least three arms in the space. A fist and a second arm, including two parallel links, are fixed to an element with a three-dimensional joint arrangement. The joint arrangement is arranged on the same symmetry axis within the element.
Patent EP-1318140-B1 (EP)
Inventor: NAKAMURA MITSUHARU
IPC: C07C233/59
Filed: 2001-09-14
Granted: 2011-05-18
Abstract: The present invention relates to an amide derivative of the formula (1), having a C5a receptor antagonistic action <CHEM>  wherein each symbol is as defined in the specification. The above-mentioned amide derivative, an optically active form thereof and a pharmaceutically acceptable salt thereof are promising as an agent for the treatment or prophylaxis of diseases or syndromes caused by inflammation caused by C5a Äe.g., autoimmune diseases such as rheumatism, systemic lupus erythematosus and the like, sepsis, adult respiratory distress syndrome, chronic obstructive pulmonary disease, allergic diseases such as asthma and the like, atherosclerosis, cardiac infarction, brain infarction, psoriasis, Alzheimer's disease and serious organ injury (e.g., pneumonia, nephritis, hepatitis and pancreatitis and the like) due to activation of leukocytes caused by ischemia reperfusion, trauma, burn, surgical invasion and the likeÜ. Moreover, they are useful as a therapeutic or prophylactic agent for the infectious diseases caused by bacteria and virus that invade via a C5a receptor.
Patent EP-1427290-B1 (EP)
Inventor: HUNTER THOMAS B
IPC: A21C11/16
Filed: 2001-09-12
Granted: 2008-03-19
Abstract: A die and cutter assembly (1) for an extruder for producing an extruded food piece containing a filling includes an elongated annular extrusion member (9). A filling tube (20) extends into the elongated annular extrusion member (9). A tube extension (24) is formed on the filling tube (20) substantially at a right angle thereto and located within the extension (22) of the elongated annular extrusion member (9). In addition, an extrusion die (13) is formed on the extension (22) of the elongated annular extrusion member (9) and a cutter member (14) having an opened driveable end (15), an elongated cutter wall (16), and an opened cutter end (17) with a cutting surface (18) for cutting extrudate to a desired length as the extrudate exits the die (13) is disposed at least partially over and reciprocally slideable on the extrusion wall (10) and operably connectable at the driveable end (15) to a drive device for reciprocatably sliding the cutter member (14) over and away from the extrusion die (13).
Patent EP-1320447-B1 (EP)
Inventor: LEBISCH HELMUT
IPC: B23B47/00
Filed: 2001-08-31
Granted: 2009-04-15
Abstract: La présente invention concerne une machine outil, notamment un marteau perforateur manuel, comprenant une chambre (10) à lubrifiant, dans laquelle est monté au moins un composant pouvant être entraîné en rotation (12), ainsi qu'un dispositif de compensation de pression (14), qui est destiné à la chambre (10) et comprend un composant de centrifugation pouvant être entraîné en rotation (16). Ce composant de centrifugation pouvant être entraîné en rotation protège au moins un canal de compensation de pression (18), qui est connecté en aval de celui-ci, dans la direction d'évacuation d'air de la chambre (10), selon la technique des fluides. Selon cette invention, le composant de centrifugation (16) est monté fixe en rotation sur le composant pouvant être entraîné en rotation (12).
Patent EP-1322307-B1 (EP)
Inventor: NEAL ROSEN
IPC: A61K31/336
Filed: 2001-07-27
Granted: 2011-09-28
Abstract: The present invention concerns methods for treating cell proliferative diseases, tumors associated with viral infections, and certain viral infections. The disclosed methods use compounds which inhibit heat shock protein 90 proteins. Such methods block Rb negative or deficient cells in the G2/M phase of the cell cycle and rapidly causes their destruction.
Patent EP-1368629-B1 (EP)
Inventor: NARGESSI R D
IPC: C12N15/09
Filed: 2001-10-05
Granted: 2009-02-11
Abstract: A method for the isolation and purification of nucleic acid such as DNA, RNA, and PNA from various sources using magnetizable cellulose or its derivatives. Adjusting the concentrations of the salt and polyalkylene glycol to the levels result in binding of nucleic acids to the magnetizable cellulose or its derivatives. Separating the nucleic acids bound to the magnetizable cellulose particles or its derivatives and eluting the nucleic acids from the particles.
Patent EP-1347685-B1 (EP)
Inventor: KERN MANFRED
IPC: A01N63/40
Filed: 2001-12-12
Granted: 2009-04-29
Abstract: Method for controlling harmful organisms in genetically modified maize plants containing a gene derived from Bacillus thuringiensis, said gene encoding and expressing protein with an insecticidal action, wherein an insecticidally active quantity of one or more compounds from the groups (a) to (f) specified in detail in the description is applied to the plants, their seeds or propagation material and/or the area in which they are cultivated: a) insecticidal organophosphorus compounds b) pyrethroids c) insecticidal carbamates d) biopesticides e) insecticidal growth regulators f) others. The inventive method makes possible a reduced application rate of crop protectants which act synergistically with the transgenic plants, in addition to an increased and wider-ranging efficiency of said transgenic plants, thus offering economic and ecological advantages.