baber/WOPTO huggingface dataset:
Patent JP-2018500905-A (JP)
Title: ナノチューブを使用した核酸ポリメラーゼ立体構造変化の検出
IPC: G01N27/414
Filed: 2015-12-17
Abstract: 本発明は、単層カーボンナノチューブ（ＳＷＮＴ）に非共有結合させた核酸ポリメラーゼを第１のヌクレオチドまたは第１のヌクレオチド類似体及び鋳型と接触させること、ならびに核酸ポリメラーゼと、立体構造が変化した核酸ポリメラーゼとの間のＳＷＮＴの第１の電気コンダクタンス変化を測定することによって、立体構造が変化した核酸ポリメラーゼを検出することを含む、核酸ポリメラーゼ立体構造の変化を検出するための方法及び組成物を提供する。本方法は、ポリヌクレオチドの配列決定に有用である。
Patent JP-2018501146-A (JP)
Title: 自動車のフロントガラスのワイピング機構用の排水カバー、自動車のフロントガラスのワイパー機構のシャフトの本体、及び、カバー及び本体を含む自動車のフロントガラスのワイパー機構
IPC: B60S1/34
Filed: 2015-12-17
Abstract: 本発明の主題は、自動車のフロントガラスのワイピング機構用の排水カバー（１）であって、前記シャフト（１１）の前記本体（２）に固定されるように適合され、前記シャフトに面する開口（５）を含み、排出開口（７）を含む溝部（６）に囲まれた、前記カバーの確動接続要素（４）を含み、前記カバーの前記確動接続要素（４）は、前記Ｘ軸に関して連続的な回転対称性を有せず、前記Ｘ軸と垂直な面における各横断面において凸状の形状を有し、さらに、前記本体の前記確動接続要素（３）は、前記カバー（１）が前記本体（２）に取り付けられたときに前記カバー（１）の前記Ｘ軸に平行な方向の移動を妨げる手段を有し、好ましくは、前記手段は少なくとも１つの突起及び／又は窪み（９）の形状をなし、好ましくは、前記手段は前記Ｘ軸に垂直であり、前記Ｘ軸は、前記シャフトに面する開口（５）を通り、前記カバー（１）が前記本体（２）に適切に取り付けられたときに前記シャフト（１１）の回転軸と一致する直線として定義される、カバー（１）である。また、本発明の主題は、本発明のカバーに対応するシャフト（１１）の本体（２）、及び、カバー（１）及び本体（２）を含む自動車のフロントガラスのワイパー機構である。
Patent JP-2018505888-A (JP)
Title: アルキルインジウム化合物の調製プロセス及びその使用
IPC: C07F5/00
Filed: 2016-02-11
Abstract: 本発明は、アルキルインジウムセスキクロリドの、費用効果が高く、環境責任を持ち、高収率、並びに高選択性及び高純度での、調製プロセスに関する。本発明により調製したアルキルインジウムセスキクロリドは、高純度、高収率であることからも、インジウム含有前駆体の、高収率並びに高選択性及び高純度での、需要に合致した調製に特に好適である。高純度であることから、調製可能なインジウム含有前駆体は、有機金属化学蒸着法（ＭＯＣＶＤ）又は有機金属気相成長法（ＭＯＶＰＥ）に特に好適である。本発明による新規なプロセスは、特に速やかなプロセス制御により、本プロセスの実施が改善されたものである。安価な、環境汚染が低レベルの原料を、目標を絞って高効率で利用することから、本プロセスは工業規模での使用にも好適である。
Patent JP-2018511496-A (JP)
Title: 段ボールウェブを製造するための機械
IPC: B31F1/24
Filed: 2016-04-11
Abstract: 本発明は、少なくとも１つのカバーウェブ（３、１９）及び少なくとも１つの波形ウェブ（７）が接着（１２）によって結合された段ボールウェブ（１３）を製造する機械に関する。この機械は、マイクロ波によって段ボールウェブ（１３）の品質を判定するため、段ボールウェブ（１３）の少なくとも１つの誘電特性を判定する少なくとも１つのマイクロ波品質判定手段（５３）を備える。
Patent JP-2018500934-A (JP)
Title: Ｃｍｐ依存性シアリダーゼ活性
IPC: C12N9/10
Filed: 2015-12-21
Abstract: 本開示は、Ｎ末端トランケーション欠失または内部欠失を有する特定のグリコシルトランスフェラーゼバリアントの特性に関する。本明細書に開示する変異体はいずれも、補基質としてのＣＭＰ活性化されたシアル酸の存在下で、かつ適切なアクセプター部位の存在下で、α−２，６−シアリルトランスフェラーゼ酵素活性を示す。本開示中で述べる基本的知見は、そのような酵素がシアリジル部分の伝達を触媒できるだけでなく、それらがグリカンからの末端結合シアル酸の加水分解開裂をも触媒できるということである。特に、シチジン−５’−一リン酸（ＣＭＰ）の存在下でグリコシルトランスフェラーゼ活性は阻害され、シアリダーゼ活性は刺激されることが見出された。シアリダーゼ活性は、基準（野生型）ｈＳＴ６Ｇａｌ−Ｉポリペプチドのポリペプチド配列中の特定範囲のアミノ酸（位置９０−１０８）の存在に依存することが見出された。Ｎ末端トランケーションバリアントにおけるこの配列部分の欠失は、ＣＭＰの存在下および非存在下で共に明らかにシアリダーゼ活性を無効にすることが見出された。よって、本明細書中で述べるＣＭＰ仲介フィードバック調節を用いる組成物、使用および方法を開示する。【選択図】図１１
Patent JP-2018513733-A (JP)
Title: 眼科手術装置
IPC: A61F9/008
Filed: 2016-04-01
Abstract: 本発明は１ピコ秒〜１ナノ秒の持続時間でレーザパルスのビーム（８）を出すのに好適なレーザ源（１）；前記レーザパルスのビームを焦点（６）にフォーカシングさせるための光学フォーカシング系（１０）；および予め決められた経路に沿って前記焦点（６）を動かすように構成されている、レーザパルスのビームを動かすためのシステムを含む、眼科手術装置に関する。レーザ源（１）は眼（４）の前部の表面（２５）の隣にフォーカシングされたピコ秒〜ナノ秒レーザパルスのビーム（８）を生成し、焦点（６）は、眼（４）の前部の対称光軸（２１）からゼロ以外の距離ｄに位置しており、レーザパルスのビームを動かすためのシステム（３０）は、眼（４）の前部の対称光軸（２１）の周りの環状領域に位置している曲線経路（１６）に沿って前記焦点（６）を動かすために、回転軸（３６）の周りでの単一の回転自由度を含み、眼科手術装置は焦点（６）における、および眼（４）の前部の対称光軸（２１）の周りの前記環状領域における曲線経路（１６）全体上での幾何光学収差を制限するような開口数を備えて構成されている。
Patent JP-2018514257-A (JP)
Title: 薬剤容器用ポンプキャップ、薬剤容器用ポンプキャップインレイ、該ポンプキャップを有する薬剤容器、及びコンピュータプログラム製品
IPC: A61M11/00
Filed: 2016-03-02
Abstract: 薬剤容器用ポンプキャップは、容器内容物を放出するための利用者によるポンプキャップの作動を記録し、報告信号をワイヤレス方式で発信し、利用者による１回又は複数回のポンプキャップの作動のための、及び、１回又は複数回のポンプキャップの作動からの信号のワイヤレス発信のための運転エネルギーが、携帯情報端末の形態である電子機器により、ワイヤレス方式で、外部から生じることを可能にするように適合された電子ユニットを含む。【選択図】 図１
Patent JP-2018515490-A (JP)
Title: キナーゼを調節する化合物の固体形態
IPC: A61K31/436
Filed: 2016-05-05
Abstract: 受容体型プロテインキナーゼｃ−Ｋｉｔ及び／またはｃ−Ｆｍｓ、及び／またはＦｌｔ３に対して活性な化合物［５−（５−クロロ−１Ｈ−ピロロ［２，３−ｂ］ピリジン−３−イルメチル）−ピリジン−２−イル］−（６−トリフルオロメチル−ピリジン−３−イルメチル）−アミンＨＣｌ塩（化合物Ｉ）及びその遊離塩基の固体形態を調製し、特性化した。また、その固体形態を使用する方法を提供する。Ｉ
Patent JP-2018517696-A (JP)
Title: （ｅ）−（５，６−ジヒドロ−１，４，２−ジオキサジン−３−イル）（２−ヒドロキシフェニル）メタノンｏ−メチルオキシムを調製する改善されたプロセス
IPC: C07D273/01
Filed: 2016-05-10
Abstract: （Ｅ）−（５，６−ジヒドロ−１，４，２−ジオキサジン−３−イル）（２−ヒドロキシフェニル）メタノンＯ−メチルオキシムを調製するプロセスであって、（ｉ）金属アルコキシドの存在下で、亜硝酸ｎ−ブチル及び亜硝酸ｔｅｒｔ−ブチルから選択される少なくとも１つの亜硝酸塩をベンゾフラン−３（２Ｈ）−オンＯ−メチルオキシム（１）と反応させて、主要な異性体として（２Ｚ，３２）−２，３−ベンゾフラン−ジオンＯ３−メチルジオキシム（２）を形成することと、（ｉｉ）前記（２Ｚ，３Ｚ）−２，３−ベンゾフラン−ジオンＯ−メチルジオキシム（２）を２−ハロエタノールと反応させて、（２Ｚ，３Ｚ）−ベンゾフラン−２，３−ジオン０２−（２−ヒドロキシエチル）Ｏ３−メチルジオキシム（３）を形成することと、（ｉｉｉ）前記（２Ｚ，３Ｚ）−ベンゾフラン−２，３−ジオン０２−（２−ヒドロキシエチル）＆−メチルジオキシム（３）を酸と反応させて、（Ｅ）−（５，６−ジヒドロ−１，４，２−ジオキサジン−３−イル）（２−ヒドロキシフェニル）メタノン（９−メチルオキシム（４）を形成することとを含むプロセスを記載する。【選択図】なし
Patent JP-2018524715-A (JP)
Title: 地理ゾーンに関する履歴データに基づいた車両制御戦略の適合
IPC: G08G1/09
Filed: 2015-06-15
Abstract: 【解決手段】本発明は、少なくとも１つの環境規制に関連付けられた少なくとも１つの地理ゾーンを経由して所定の目的地に至る反復利用される固定ルートを運行する路上走行車両の車両制御戦略を適合させる方法及びシステムに関する。車両が地理ゾーンに接近していることを特定すると、１台又は数台の車両が過去に行った同ゾーンの通過の際に収集された履歴データにアクセスし、履歴データと環境規制とに基づいて同地理ゾーン内での車両制御戦略を適合させる。本発明は、反復利用されるルートに沿って走行する車両は、車両制御戦略の適合の際に、同ルートの過去の通過に関する履歴データを有意義に活用することができるという知見に基づいている。【選択図】図１
Patent JP-2018530736-A (JP)
Title: マルチパルスレーザー誘起プラズマスペクトル分析機器を採用して鉄鋼サンプル成分を検出する方法
IPC: G01N21/71
Filed: 2016-10-11
Abstract: 【課題】マルチパルスレーザー誘起プラズマスペクトル分析機器を採用して鉄鋼サンプル成分を検出する方法を提供すること。 【解決手段】本発明はマルチパルスレーザー誘起プラズマスペクトル分析機器を採用して鉄鋼サンプル成分を検出する方法、特にピコ秒及びナノ秒レーザーパルス幅を含むマルチパルスレーザー誘起プラズマスペクトル分析機器を採用して鉄鋼サンプル成分を検出する方法に関し、レーザー誘起光源はナノ秒オーダ及びピコ秒オーダの超短パルスを含むレーザー光源であり、１つのパルスレーザーで２つのパルスレーザーであるナノ秒レーザー及びピコ秒レーザーを発生することができ、同じ出力及び合焦光路によってこの２つのパルスレーザーを被検出サンプルの同じ位置に合焦させ、第一ナノ秒レーザーパルスを利用してサンプルの表面を照射してプラズマを生成し、その後第二ピコ秒レーザーパルスを利用してプラズマを照射してスペクトル線発射を補強する。 【選択図】図１
Patent JP-2019119965-A (JP)
Title: Aizome method of berry of star moon linden tree enhancing spot-like concentration difference of aizome, and rosary beads using berry of indigo-dyed star-moon linden tree
Inventor: KAWABATA RYOJI
IPC: B44C5/06
Filed: 2018-01-08
Abstract: To provide a method for aizome of rosary beads using berries of a star moon linden tree, which realizes by enhancing spot-like concentration difference.SOLUTION: A relatively thin aizome liquid is left in film on a smooth spherical part having no unevenness of a berry of a star moon Linden, and a large amount of aizome liquid is spottedly left in a recessed part in a moon part and a star part of a recessed part as compared with a spherical part. Then, when an indigo is oxidized to develop a color by exposing aizome liquid which is shallowly or deeply infiltrated into the internal tissues of the star moon Linden to the air, different spot-like color shade contrast is emphasized by the difference of the amount of the infiltrated aizome liquid.SELECTED DRAWING: Figure 2
Patent JP-2019122887-A (JP)
Title: Continuous centrifuge and operational method of the same
Inventor: KOMURA TAKAHITO
IPC: B04B13/00
Filed: 2018-01-12
Abstract: To provide a continuous centrifuge in which a rotary shaft and a mechanical seal are configured to be separable when a rotor is rotating.SOLUTION: The continuous centrifuge comprises: a drive part rotating a rotor; a rotary shaft 116 having a through hole inside; a mechanical seal 228B having a sample supply hole communicating with the rotary shaft 116 and capable of being in contact with and separating from the tip of the rotary shaft 116; and a sample circulation line 129B connected to the mechanical seal 228B, where the sample circulation line 129B is formed in a state where the mechanical seal 228B is in contact with the rotary shaft 116 as shown in Fig.2 (2), and the rotor is accelerated while supplying a sample to the rotor. When the rotation speed has reached a specified value and settled, the sample supply is stopped, the supply of high pressure air 252B is stopped as shown in Fig.2 (1) and a seal holder 227B is moved downward by a spring 230B, and operation of centrifugal separation is performed for a set operation time in a state where the mechanical seal 228B and the rotary shaft 116 are separated.SELECTED DRAWING: Figure 2
Patent JP-2019122625-A (JP)
Title: Game machine
Inventor: ENOKIDO SHINSUKE
IPC: A63F5/04
Filed: 2018-01-17
Abstract: To predict whether a player is in a "hot" state or not by following an RT state.SOLUTION: A game machine of the present invention can be shifted among a plurality of RT states, and instruction information can be notified for displaying a combination of symbols which is advantageous to a player corresponding to an internal winning combination. A first score is given according to the type of an RT state, a second score is given according to the type of the internal winning combination, and a period for notifying the instruction information is determined on the basis of the calculation result using the score given in the game.SELECTED DRAWING: Figure 308
Patent JP-2019122648-A (JP)
Title: Game machine
Inventor: OGURA TOSHIO
IPC: A63F7/02
Filed: 2018-01-18
Abstract: To provide a game machine with an improved presentation effect.SOLUTION: When a super ready-to-win A is to occur, as shown at (C), a character 31AK001, which is a friendly character, is displayed in an image display device 5 and a ready-to-win presentation is started. When a prescribed time is elapsed from a start of the ready-to-win presentation, such as a termination of an introduction portion of the ready-to-win presentation, a title 31AK002 of the super ready-to-win A is displayed across the whole screen of the image display device 5 as shown at (D), and from a speaker 8, a sound corresponding to the title name of the ready-to-win is outputted. Thereby, the title of the super ready-to-win A is notified.SELECTED DRAWING: Figure 9
Patent JP-2019126744-A (JP)
Title: Method for manufacturing filter molded article
Inventor: SANO TOMONORI
IPC: A23F3/16
Filed: 2018-01-19
Abstract: To firstly provide a method for manufacturing a filter molded article with high manufacturing efficiency using a laser processing technique, and the filter molded article.SOLUTION: Provided is a method for manufacturing a filter molded article including a process of cutting the filter by using laser.SELECTED DRAWING: Figure 1
Patent JP-2019126265-A (JP)
Title: Bush cutter
Inventor: ITO SHUSUKE
IPC: A01D34/416
Filed: 2018-01-22
Abstract: To provide a technique capable of using an automatic delivery mechanism of a cord holder even when rotary speed of the cord holder is controlled to target speed.SOLUTION: A bush cutter comprises: an operation rod; a cord holder provided on a front end of the operation rod and has an automatic delivery mechanism of a cord; a motor for driving the cord holder to rotate; and a controller for controlling the motor. The automatic delivery mechanism of the cord holder is configured to automatically deliver the cord, when rotary speed of the cord holder exceeds a prescribed speed. The controller temporarily executes speed increase operation of the motor so that, the rotary speed of the cord holder exceeds the prescribed speed when the prescribed condition is satisfied.SELECTED DRAWING: Figure 5
Patent JP-2019126922-A (JP)
Title: Liquid discharge device, liquid discharge method, liquid discharge program, and image forming device
Inventor: YAMAMOTO NAOHIRO
IPC: B41J2/01
Filed: 2018-01-22
Abstract: To improve discharge accuracy and coating quality of liquid.SOLUTION: A first acquisition part acquires image data of an image which is formed on a recording medium, and a second acquisition part acquires shape data related to a three-dimensional shape of the recording medium. A creation part creates scanning-plane image data of a scanning plane of a discharge part for discharging liquid droplets on the basis of the image data and the shape data. At this time, the creation part creates the scanning-plane image data on the basis of an inclination angle of a portion which is inclined by a prescribed angle or larger at a surface of the recording medium. An intermediate processing part creates discharge data of discharge resolution which is the same as resolution of the scanning plane of the discharge part by applying prescribed half-tone processing to the scanning plane image data.SELECTED DRAWING: Figure 9
Patent JP-2018121056-A (JP)
Title: Etching solution for tungsten and GST film
Inventor: LIU DAR WEN
IPC: H01L21/28
Filed: 2018-01-23
Abstract: PROBLEM TO BE SOLVED: To provide an etching solution with excellent selective etching characteristics for tungsten based and GST based metals.SOLUTION: An etching solution suitable for both tungsten-containing metal and GST metal includes water, at least one phenol derivative compound having at least two hydroxyl groups, at least one strong base selected from the group consisting of (i) a quaternary base, (ii) an organic amine, and (iii) a metal hydroxide, optionally an ammonium salt of an organic acid, and optionally a water miscible solvent, and the pH is 10 or more, and the etching solution is substantially free from a peroxide oxidizing agent and a metal ion-containing oxidizing agent.SELECTED DRAWING: None
Patent JP-2019127762-A (JP)
Title: Fitting
Inventor: YANAI SATOSHI
IPC: E05D15/06
Filed: 2018-01-25
Abstract: To provide a fitting that can prevent the sliding panel from meandering while making an upper surface of a lower frame substantially flat.SOLUTION: A fitting includes sliding panels 1a, 1b and a lower frame 2. The sliding panels 1a, 1b have a door wheel 3 at their lower portions, and the door wheel 3 has a groove 4 at the outer periphery. The lower frame 2 has a recessed section 5 provided on its upper surface 2a, a rail 6 which is located on the indoor side of the recessed section 5 and is engaged with the groove 4 of the door wheel 3, a depending piece guide groove 8 which is located on the indoor side of the rail 6 and guides a depending piece 7 of the sliding panels 1a, 1b, and a horizontal piece 9 provided from the root of the rail 6 toward the depending piece guide groove 8. An upper end of the rail 6 is substantially the same height as the lower frame upper surface 2a. Air tightness members 10a and 10b are provided between the horizontal piece 9 of the lower frame 2 and the depending piece 7 of the sliding panels 1a and 1b, and between an indoor side wall 25 of the depending piece guide groove 8 and the depending piece 7 of the sliding panels 1a, 1b, respectively.SELECTED DRAWING: Figure 1
Patent JP-2019126551-A (JP)
Title: Game machine
Inventor: OGURA TOSHIO
IPC: A63F7/02
Filed: 2018-01-25
Abstract: To provide appropriate wiring constitution.SOLUTION: A connection wiring member 55AK01 has a first shape where at least one signal wiring of a plurality of signal wiring is a straight line or a nearly straight line in an area 55AK10Z, whereas the other signal wiring has a second shape such as a meandering shape different from the first shape. Wiring length of at least a part of signal wiring included in the plurality of signal wiring becomes identical or almost identical. The connection wiring member 55AK01 is formed so that the whole has an L-shape or an almost L-shape by being bent in the area 55AK2Z.SELECTED DRAWING: Figure 40
Patent JP-2021052812-A (JP)
Title: Emotion analysis system
Inventor: MASAOKA HISAKAZU
IPC: A61B5/16
Filed: 2018-01-26
Abstract: To provide an emotion analysis system for analyzing an emotion of a subject and causing the result to be notified of.SOLUTION: An emotion analysis system 10 includes a detection section 11 for detecting a heart rate and body temperature of a subject. The emotion analysis system 10 includes an acquisition section 12 for acquiring the heart rate and body temperature detected by the detection section 11 so as to analyze an emotion of the subject. The emotion analysis system 10 includes a notification section 13 for classifying the emotion analyzed by the acquisition section 12 into multiple pieces and causing them to be notified of. The notification section 13 includes a display section. The emotion is classified into multiple pieces. The multiple pieces of emotions are assigned to multiple different colors. The notification section 13 displays a color corresponding to a piece of emotion by the display section.SELECTED DRAWING: Figure 1
Patent JP-2018141554-A (JP)
Title: Transmission belt
Inventor: OZAKI TOSHIKI
IPC: C08K3/00
Filed: 2018-01-29
Abstract: PROBLEM TO BE SOLVED: To improve hardness and modulus of a cured product of a rubber composition for a transmission belt, the rubber composition being mainly composed of an ethylene-α-olefin elastomer, without degrading cold resistance, heat resistance, adhesiveness, flex fatigue resistance and wear resistance.SOLUTION: The transmission belt is formed from a cured product of a rubber composition which includes a rubber component including an ethylene-α-olefin elastomer, an α,β-unsaturated carboxylic acid metal salt, magnesium oxide, an organic peroxide, and an inorganic filler, and which is adjusted so that the ratio of magnesium oxide is 2-20 pts.mass relative to 100 pts. mass of the rubber component, and 5 pts.mass or more relative to 100 pts.mass of α,β-unsaturated carboxylic acid metal salt. The ratio of α,β-unsaturated carboxylic acid metal salt may be about 5-40 pts.mass relative to 100 pts.mass of the rubber component. The transmission belt is applicable as a transmission belt such as a raw edge cogged V belt used for CVT driving.SELECTED DRAWING: Figure 1
Patent JP-2019132547-A (JP)
Title: Outdoor unit of air conditioning device
Inventor: KOIKE SHIRO
IPC: F24F13/30
Filed: 2018-01-31
Abstract: To keep an interval between heat exchangers, in an outdoor unit including a plurality of the heat exchangers.SOLUTION: First and second heat exchangers (40, 50) disposed in an outdoor unit respectively include outer peripheral heat exchange portions (41, 51) along an outer periphery of a casing, and inner heat exchange portions (42, 52) extended to an inner side of the casing from the outer peripheral heat exchange portions (41, 51). An upper end partitioning plate (60) is disposed at an upper end side of the inner heat exchange portions (42, 52) opposed to each other. The upper end partitioning plate (60) includes a first holding portion (70) to which an upper end portion of the first inner heat exchange portion (42) is fitted, and a second holding portion (75) to which an upper end portion of the second inner heat exchange portion (52) is fitted.SELECTED DRAWING: Figure 3
Patent JP-2019133886-A (JP)
Title: Case-combined switch and input device
Inventor: INOUE ATSUO
IPC: H04M1/23
Filed: 2018-02-02
Abstract: To provide a case-combined switch that is easy to be assembled and excellent in design.SOLUTION: A case-combined switch 10 includes a housing 20, a pressure sensitive sensor 30, and a back plate 40. A recess 21 is formed in the housing 20, and the bottom surface of the recess 21 is a plate portion 22. The pressure sensitive sensor 30 and the elastic member 50 are accommodated in the recess 21. The back plate 40 is disposed so as to close the opening of the recess 21, and the back plate 40 is fixed by a claw portion 23 formed in the housing 20. The case-combined switch 10 is formed with the recess 21, the claw portion 23, and a stepped portion 24 in the housing 20, and can be assembled by disposing the pressure sensitive sensor 30 and the elastic member 50 in the recess 21, and then inserting the back plate 40 into a space formed by the claw portion 23.SELECTED DRAWING: Figure 1
Patent JP-2018075038-A (JP)
Title: Bispecific antibody fragments to neurological disease proteins and methods of use
Inventor: MICHAEL SIERKS
IPC: A61P25/28
Filed: 2018-02-05
Abstract: PROBLEM TO BE SOLVED: To provide bispecific antibody fragments to neurological disease proteins and methods of use.SOLUTION: The invention provides a therapeutic agent comprising a bispecific recombinant antibody fragment that selectively removes a protein associated with a neurological disease, and a method for using the therapeutic agent for treating the neurological disease. Some embodiments provide a bispecific antibody fragment comprising: (a) a first ligand that specifically recognizes a protein associated with a neurological disease; and (b) a second ligand that specifically activates a classical complement pathway component or directly activates microglial cells.SELECTED DRAWING: None
Patent JP-2019135939-A (JP)
Title: Cell count method, cell count device and cell culture method
Inventor: KOBAYASHI TATSUYA
IPC: C12Q1/06
Filed: 2018-02-07
Abstract: SOLUTION: On a same position on a same container 3, a base image in which, no reagent is put into the container 3, and a dyeing image in which the reagent is put into the container 3 and cell nucleuses of cells C are dyed, are imaged, and a plurality of sets of the base image and dyeing image are collected, then the plurality of sets of base image and dyeing image are used for learning the same to an algorithm of deep learning. In the container 3 storing cells C being a counting object, no reagent is put into the container 3 and the container 3 is imaged, then, based on the image, the learned algorithm recognizes cell nucleuses of cells C and counts a number of the cell nucleuses.EFFECT: As an effect, without dyeing cells, a number of cells can be counted.SELECTED DRAWING: Figure 2
Patent JP-2019052286-A (JP)
Title: Thermosetting resin composition
Inventor: MORIWAKI YUYA
IPC: C08L33/04
Filed: 2018-02-08
Abstract: To provide a thermosetting resin composition using a transesterification reaction as a curing reaction, which has a good curability and can be used in various applications.SOLUTION: An organic solvent-based or water-based thermosetting resin composition comprises, as essential components: a polymer (A) comprising, as structural units, monomers having a (meth)acrylic acid tertiary alkyl ester and a hydroxyl group; and a transesterification catalyst (B).SELECTED DRAWING: None
Patent JP-2019140621-A (JP)
Title: Control method of electronic equipment and electronic equipment
Inventor: SAWAOKA TOSHIHIRO
IPC: H04N21/442
Filed: 2018-02-14
Abstract: To provide electronic equipment which allows for narrow down and extraction of a desired program by using external information and information built internally in combination.SOLUTION: A control method of electronic equipment acquires a first program list, ranking first multiple programs, externally in a program list generation part for managing the program list, and when forming a second program list, ranking second multiple programs existing as the same program in the first multiple programs, forms a second program list ranking the second multiple programs, without breaking the ranking of the first multiple programs.SELECTED DRAWING: Figure 4
Patent JP-2019146296-A (JP)
Title: Ac power supply device
Inventor: OTAKE HIROTAKA
IPC: H02M7/48
Filed: 2018-02-16
Abstract: To reduce a switching loss and an overall loss of an AC power supply device.SOLUTION: An AC power supply device 1 comprises: input transistors 11 and 12 defining a connection node mutually therebetween as a neutral point X of three-phase output; a transistor bridge 20* (*=U, V, W) consisting of PWM control bridges 20*1 to 20*2 each including two switch elements; a transformer T* connected to an output end of the transistor bridge 20*; a reactor Ls* connected to the transformer T*: and a smoothing capacitor 40* connected to the reactor Ls*. The transformer T* is an auto-transformer and includes a core 33*, and coils 31* and 32* of which respective one-side ends are connected to output ends of the PWM control bridges 20*1 and 20*2 and mutually coupled via the core 33* and respective other-side ends are connected to the reactor Ls*. The coils 31* and 32* are wound in such a direction that magnetic flux generated inside of the core 33* is mutually cancelled.SELECTED DRAWING: Figure 1