baber/WOPTO huggingface dataset:
Patent MX-2020003594-A (MX)
Inventor: SHEN NING
IPC: A61K31/519
Filed: 2018-10-05
Abstract: La presente invención se refiere a métodos y composiciones que incluyen agentes e inhibidores de la quinasa p38 que regulan la expresión de DUX4 y de los genes corriente abajo que incluyen, mas no se limitan a, ZSCAN4, LEUTX, PRAMEF2, TRIM43, MBD3L2, KHDC1L, RFPL2, CCNA1, SLC34A2, TPRX1, PRAMEF20, TRIM49, PRAMEF4, PRAME6, PRAMEF15, o ZNF280A. Se divulgan métodos útiles para tratar una enfermedad asociada con la expresión anormal de DUX4 y de los genes corriente abajo (por ejemplo, distrofia muscular facioescapulohumeral).
Patent MX-2020004877-A (MX)
Title: Devices and methods for puncturing a capsule to release a powdered medicament therefrom.
Inventor: ELLWANGER COLLEEN
IPC: A61M15/00
Filed: 2015-06-04
Abstract: A device (100) for puncturing a capsule (219) to release a powdered medicament therefrom includes a chamber (210) for receiving the capsule. The capsule includes opposing domes and a cylindrical wall portion defined by a capsule wall radius r. The device further includes a mechanism (230) for puncturing at least one hole in at least one dome. A center of each hole is located within an annular puncture region situated at no less than 0.4r, and a total surface area of all puncture holes is between about 0.5% and about 2.2% of a total surface area of the capsule. The annular puncture region may, for example, be situated between about 0.4r and about 0.8r, or between about 0.4r and about 0.6r.
Patent MX-2020005033-A (MX)
Title: Primate retinal pigment epithelium cell-specific promoter.
Inventor: ROSKA BOTOND
IPC: A01K67/027
Filed: 2018-11-15
Abstract: The present invention to a method for expressing an exogenous gene specifically in cells of the retinal pigment epithelium of a primate, this method comprising the step of delivering an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1, or consisting of a nucleic acid sequence of at least 400 bp having at least 80% overall identity to the sequence of SEQ ID NO:1, to cells of the retinal pigment epithelium of the primate, wherein this isolated nucleic acid molecule specifically leads to the expression of an exogenous gene in cells of the retinal pigment epithelium of primates when a nucleic acid sequence coding for the exogenous gene is operatively linked to this isolated nucleic acid molecule.
Patent MX-2020009931-A (MX)
Title: Electrically operated steering system for a vehicle.
Inventor: TRAUTNER FLORIAN
IPC: B62D5/00
Filed: 2020-09-23
Abstract: The invention relates to an electrically operated steering system (1) for a vehicle (2) with a rack (3) for attaching the steering system (1) to a vehicle frame of the vehicle (2), two steerable wheels (4) that are pivotably attached to the rack (3), a rod element (5) arranged on the rack (3), which is slidable in its longitudinal direction in relation to the rack (3), a kinematic unit (13) which is coupled to the rod element (5) and which transforms a movement of the rod element (5) into a steering rotation of the wheels (4), an electric machine (6), which is mechanically connected to the rod element (5) for effecting the movement of the rod element (5), and a lateral force absorbing mechanism (7) which is configured for absorbing a lateral force produced by the kinematic unit (13) in relation to the rod element (5). The invention further relates to a vehicle (2) comprising such a steering system (1).
Patent MX-2020011058-A (MX)
Title: Methods and apparatus for an aerodynamic trucking system.
Inventor: SENATRO RICHARD P
IPC: B62D29/00
Filed: 2020-10-19
Abstract: A streamlined fairing assembly for attaching to a tractor trailer. The streamlined fairing assembly may comprise a front valance fairing and a trailing valance comprising a transition. The transition may extend out of the side skirt fairing a distance from the centerline of the trailer. The side skirt fairing and rear skirt fairing are attached to the trailer by one or more struts.
Patent MX-2021000066-A (MX)
Title: Methods and compositions for preparing tagatose from fructose.
Inventor: ZANGHELLINI ALEXANDRE
IPC: C12N9/90
Filed: 2019-07-03
Abstract: Disclosed herein are compositions and methods for preparing tagatose from fructose, more particularly, compositions comprising thermophilic fructose C4-epimerases derived from thermophilic microorganisms and methods for preparing tagatose from fructose using the compositions.
Patent MX-2021000244-A (MX)
Title: Systems and methods for improving the stability of non-ferrous metals on a conveyor.
Inventor: THAKUR ADWAIT A
IPC: B03C1/23
Filed: 2019-07-08
Abstract: A conveying system, such as a conveying system for material including non-ferrous metals, includes a conveying belt and a stabilizer. The conveying belt includes a conveying surface and is adapted to convey the material on the conveying surface. The stabilizer is configured to apply a stabilizing force onto the material on the conveyor belt such that the material is stabilized while being conveyed. A method of stabilizing material on a conveyor belt includes receiving the material on the conveying surface of the conveyor belt, conveying the material at a conveying speed with the conveyor belt, and applying the stabilizing force onto the material with a stabilizer such that vertical displacement of at least some of the material is dampened and/or minimized at the conveying speed.
Patent MX-2021000364-A (MX)
Title: Convertible surgical access port.
Inventor: FORSELL PETER
IPC: A61B17/34
Filed: 2014-01-15
Abstract: A interconnectable port is provided. The interconnectable port is adapted to be at least partially placed in an incision in a patient's body. The interconnectable port comprises a first and second port adapted be interconnected to form the interconnectable port, wherein the second port is disconnectable from the first port, wherein the first port is connected to a first portion of a flexible wall, and the second port is connected to a second portion of the flexible wall, and wherein the flexible wall is adapted to form a chamber.
Patent MX-2021003490-A (MX)
Title: Combination therapy for the treatment of uveal melanoma.
Inventor: HERGENROTHER PAUL J
IPC: A61K31/519
Filed: 2019-10-03
Abstract: Synergistic drug combinations with the small molecule PAC-1 against uveal or cutaneous melanoma. There are no current targeted drug treatments for the mutations associated with uveal melanoma. Despite primary radiation or surgical therapy, up to 50% of patients eventually develop metastatic disease, for which there is no standard therapy nor treatment shown to improve overall survival. Drug combinations with PACâ1 allow the use of lower dosages of this compound that result in cancer cell death in uveal melanoma. Drug combinations of PAC-1 with the kinase inhibitor entrectinib have shown a synergistic effect against uveal melanoma cell lines. Specifically, PAC-1 and entrectinib are synergistic against wild-type and mutant uveal melanoma cell lines (e.g., GNAQ and GNA11).
Patent MX-2021006253-A (MX)
Title: Gene therapies for neurodegenerative disease.
Inventor: ABELIOVICH ASA
IPC: C07K14/775
Filed: 2019-11-26
Abstract: The disclosure relates, in some aspects, to compositions and methods for treatment of neurodegenerative disease, for example Alzheimer's disease. In some embodiments, the disclosure provides expression constructs comprising a transgene encoding an APOE protein isoform or a portion thereof, an inhibitory nucleic acid targeting an APOE gene or a portion thereof, or any combination of the foregoing. In some embodiments, the disclosure provides methods of treating Alzheimer's disease by administering an expression construct to a subject in need thereof.
Patent MX-2021006769-A (MX)
Title: Polymer compositions with low warpage.
Inventor: LI FENGKUI
IPC: C08K3/34
Filed: 2020-02-19
Abstract: Polymer compositions and uses thereof are described. A polymeric composition can include a polyolefin polymer and a nucleating agent having an average particle size of less than 2 micrometers.
Patent MX-2021007596-A (MX)
Title: Improved loop-fermenter.
Inventor: CHRISTENSEN IB
IPC: C12M1/00
Filed: 2020-01-24
Abstract: The present invention relates to a fermentation reactor comprising a loop-part and a top tank, said loop-part comprising a downflow part, connected to an upflow part via a U-part, wherein the top tank comprises: (i) a first outlet connecting the top tank to the downflow part of the loop-part and allowing a fermentation liquid present in the top tank to flow from the top tank into the loop-part; (ii) a first inlet connecting the top tank to the upflow part of the loop-part, allowing fermentation liquid present in the loop-part to flow from the loop part into the top tank; and (iii) a vent tube for discharging effluent gasses from the top tank; wherein the top tank further comprises a visual inspection means.
Patent MX-2021009491-A (MX)
Title: Glycyrrhetinic acid derivatives for use in treating hyperkalemia.
Inventor: LEADBETTER MICHAEL
IPC: A61P5/40
Filed: 2020-02-06
Abstract: The present invention provides a compound of formula (I) or a salt thereof: (F ormula (I)) wherein X, L, V, R1, R2, R3 and R4, are as defined herein. The claimed compounds inhibit the enzyme 11-hydroxysteroid dehydrogenase type 2 (11-HSD2) and as a result are useful in the treatment of hyperkalemia by preventing cortisol from being oxidised to cortisone and thus allowing it to occupy the mineralocorticoid receptor, thus stimulating potassium excretion.
Patent MX-2021009732-A (MX)
Title: Apparatus and method for stereo filling in multichannel coding.
Inventor: HELMRICH CHRISTIAN
IPC: G10L19/008
Filed: 2018-08-16
Abstract: An apparatus for decoding an encoded multichannel signal of a current frame to obtain three or more current audio output channels is provided. A multichannel processor is adapted to select two decoded channels from three or more decoded channels depending on first multichannel parameters. Moreover, the multichannel processor is adapted to generate a first group of two or more processed channels based on said selected channels. A noise filling module is adapted to identify for at least one of the selected channels, one or more frequency bands, within which all spectral lines are quantized to zero, and to generate a mixing channel using, depending on side information, a proper subset of three or more previous audio output channels that have been decoded, and to fill the spectral lines of frequency bands, within which all spectral lines are quantized to zero, with noise generated using spectral lines of the mixing channel.
Patent MX-2021010237-A (MX)
Title: Packaged electronic module and manufacturing method thereof.
Inventor: POCHIC SEBASTIEN
IPC: G06K19/07
Filed: 2020-03-11
Abstract: The present invention is a packaged electronic module with embedded electronics for use in smart cards. This invention assembles a plurality of electronics components on a flexible printed circuit, together with an integrated circuit chip and a contact plate, into a module. This module can then be embedded into a plastic card, using regular milling techniques, by a card manufacturer. This method packages the plurality of electronics components into a module. The present invention provides a business with the capability to avoid additional capital expenditure required for special equipment and enables all existing card manufacturers to manufacture smart cards with embedded electronics.
Patent MX-2021012496-A (MX)
Title: Article top engaging device, article carrier and blank therfor.
Inventor: SUZUKI TSUGIHIKO
IPC: B65D71/42
Filed: 2020-04-10
Abstract: Aspects of the disclosure relate to an article top engaging device, a carrier for packaging one or more articles and a blank for forming the carrier. The article top engaging device comprises an engaging panel (12; 112; 212; 312; 412; 512; 612; 712) having at least one top-receiving opening (A1, A2, A3, A4, A5, A6, A7, A8) defined by a perimeter which defines a notional circle (NC). The perimeter is interrupted by at least three relief elements (C1, C2, C3, C4, C5, C6, C7, C8, C9, C10, C11) each extending radially away of the center of the notional circle. The perimeter comprises a toothed segment (S1) and a toothless segment (S2). The toothed segment comprises at least two tooth edges (31, 32, 33, 34, 35, 36; 231, 232, 233, 234, 235, 236) for bearing a substantially vertical load.
Patent MX-2021014109-A (MX)
Title: Treatment of systolic dysfunction and heart failure with reduced ejection fraction with the compound(r)-4-(1-((3-(difluoromethyl) -1-methyl-1h-pyrazol-4-yl)sulfonyl)-1-fluoroethyl)-n-(isoxazol-3 -yl)piperidine-1-carboxamide.
Inventor: CARLSON TIMOTHY
IPC: A61K31/454
Filed: 2020-05-18
Abstract: Provided herein are methods, use, and compositions for treating systolic dysfunction such as heart failure with reduced ejection fraction.
Patent MX-2022000024-A (MX)
Title: Method and apparatus for improving furnace temperature uniformity.
Inventor: ROBERTSON THOMAS F
IPC: F23N1/02
Filed: 2022-01-03
Abstract: A method includes firing a first burner into a furnace process chamber in a first initial condition, firing a second burner into the process chamber in a second initial condition, and measuring temperature at each of an array of locations in the process chamber. The first burner is adjusted to a first adjusted condition while the second burner is being fired at the second initial condition, and a resulting first temperature change is measured at each of the locations. The second burner is adjusted to a second adjusted condition while the first burner is being fired at the first initial condition, and a resulting second temperature change is measured at each of the locations. The measured first and second temperature changes are recorded as reference data for adjusting burner conditions to adjust temperatures at each of the locations. The method can thus be used to improve temperature uniformity throughout the array of locations.
Patent MX-2022004903-A (MX)
Title: Improved light for underground mining and system for tracking underground assets.
Inventor: JONES RYAN
IPC: F21V23/00
Filed: 2019-08-07
Abstract: A lighting unit for use in low lighting environments such as underground mines is provided. The lighting unit includes a main housing having a front opening and a cavity, a first visual lighting assembly positioned within the cavity of the main housing that emits light in the visible spectrum, and a second ultraviolet lighting assembly positioned a fixed distance from the first visual lighting assembly within the cavity of the main housing that emits light in the ultraviolet spectrum. The lighting unit is part of a system for detecting patterns on objects having reflective or high visibility colored material thereon. In addition to the lighting unit, the system includes a camera having a field of view within which the system is configured to detect patterns of reflective or high visibility colored material on one or more objects, a warning device to alert the operator when a marked object enters the camera's field of view. A controller/processor is programmed to detect when a pattern of reflective or high visibility colored material enters the camera's field of view. A variety of patterns can be used, and the controller can be programmed to associated each pattern with a specific object.
Patent MX-2022005129-A (MX)
Title: Adjustable bearing supports for single-axis trackers.
Inventor: ALMY CHARLES
IPC: H02S30/10
Filed: 2020-10-29
Abstract: Adjustable bearing supports for single-axis trackers supported by truss foundations. A two-piece assembly joins a pair of adjacent truss legs to form a rigid foundation while providing a movable support for a tracker bearing housing assembly or other structure. The movable support may slide in-plane, or alternatively, enable the bearing housing assembly to slide and rotate with respect to the truss cap structure joining the adjacent truss legs.
Patent MX-2022007884-A (MX)
Title: Coated pipe resistant to casing wear.
Inventor: MENCAGLIA XAVIER
IPC: F16L58/08
Filed: 2020-12-22
Abstract: The invention relates to a tubular steel pipe (1, 21) which is sleeved or integrally threaded, comprising at least one first male threaded end, an inner surface (8, 28) and a metal deposition layer (10, 10p, 10b, 10m) on the inner surface (8, 28) and having a thickness of between 0.01 mm and 0.8 mm deposited on all or part of the inner surface (8, 28) of the pipe.
Patent MX-2022008278-A (MX)
Title: Use of cannabinoids in the treatment of epilepsy.
Inventor: GUY GEOFFREY
IPC: A61K31/05
Filed: 2016-12-13
Abstract: The present disclosure relates to the use of cannabidiol (CBD) for the reduction of total convulsive seizure frequency in the treatment of "treatment-resistant epilepsy" (TRE). In particular, the disclosure relates to the use of CBD of treating TRE when the TRE is Dravet syndrome; myoclonic absence seizures or febrile infection related epilepsy syndrome (FIRES). The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).
Patent MX-2022008801-A (MX)
Title: Activity-specific cell enrichment.
Inventor: LIU JIA
IPC: C12N15/65
Filed: 2021-01-15
Abstract: An activity-specific cell-enrichment method, capable of selection of high-performing host cells and/or expression vectors from a genetically diverse pool of host cells that can comprise expression vectors is provided.
Patent MX-2022009137-A (MX)
Title: Preferentially expressed antigen in melanoma (prame) t cell receptors and methods of use thereof.
Inventor: HANSEN JOHANNA
IPC: C07K14/47
Filed: 2021-01-22
Abstract: The present invention provides isolated T cell receptors (TCRs) that specifically bind to an HLA-displayed cancer testis antigen preferentially expressed antigen in melanoma (FRAME) peptide, as well as therapeutic and diagnostic methods of using those isolated TCRs.
Patent MX-2022009529-A (MX)
Title: Cuffed and non-cuffed dialysis catheter systems and methods.
Inventor: VELARDE FRANZ E
IPC: A61M1/36
Filed: 2021-02-04
Abstract: The present disclosure provides a catheter system including a plurality of fenestrations along the shaft of the catheter, wherein the fenestrations allow for continuous or intermittent infusion of antiseptics and/or antibiotics to avoid and treat bacterial colonization or infection of the subcutaneous tract and to minimize subcutaneous tunnel colonization and fibrin sheath in symptomatic or asymptomatic patients. The present catheter system can also include a removable abrasive component on the catheters tip to assist with mechanical debridement of subcutaneous tract and intravascular fibrin sheath.
Patent MX-2022009575-A (MX)
Title: Method for facilitating maturation of the mammalian immune system.
Inventor: FRESE STEVEN
IPC: A23L33/135
Filed: 2018-12-14
Abstract: The inventions described herein relate generally to the use of compositions to increase output of acetate and lactate while reducing pH and the levels of pathogenic bacteria and inflammation in the gut of a nursing infant mammal including humans. These compositions generally comprise one or more bacterial strains selected for their growth on mammalian milk oligosaccharides, a source of mammalian milk oligosaccharides, and, optionally, nutritive components required for the growth of that infant mammal.
Patent MX-2022010699-A (MX)
Title: A decoder and corresponding methods to signal picture partitioning information for slices.
Inventor: ESENLIK SEMIH
IPC: H04N19/00
Filed: 2021-02-20
Abstract: A method of coding implemented by a decoding device and a decoder are disclosed, the method comprising: obtaining a bitstream for a current picture; obtaining a quantity of tiles in a tile row of the current picture; obtaining a value of an address of a current slice, the current slice is comprised in the current picture; obtaining a value of tileX according to the value of the address of the current slice; parsing an indication value for a slice width from the bitsteam for the current picture, when a difference value between the quantity of tiles in the tile row of the current picture and the value of tileX is not equal to a first threshold.
Patent MX-2022011289-A (MX)
Title: Cd22 targeting-moiety for the treatment of b-cell acute lymphoblastic leukemia (b-all).
Inventor: MENÉNDEZ BUJÁN PABLO
IPC: A61K39/00
Filed: 2021-03-11
Abstract: The present invention provides therapeutics for the treatment of CD22-positive cancers such as B-cell acute lymphoblastic leukemia (B-ALL). In particular, the present invention provides an anti-CD22 monoclonal antibody whose scFv as a part of chimeric antigen receptors (CAR) T-cells can target the first Ig extracellular domain of the CD22 antigen, the farthest domain from the membrane, for use in the treatment of CD22-positive cancers.
Patent MX-2022011388-A (MX)
Title: Surfactant composition.
Inventor: AONO KEITA
IPC: C11D1/28
Filed: 2021-03-16
Abstract: The present invention is a surfactant composition containing: (a) a sulfosuccinic acid branched alkyl ester having a C9 or C10 branched alkyl group; and (b) a surfactant [other than (a)].
Patent MX-2022013080-A (MX)
Title: A combination of vaccines to prophylactically treat a pig.
Inventor: WITVLIET MAARTEN HENDRIK
IPC: A61K39/12
Filed: 2021-04-19
Abstract: The invention pertains to a combination of a first vaccine comprising anon-replicating immunogen of porcine circovirus type 2 (PCV-2) and a non-replicating immunogen of Mycoplasma hyopneumoniae, and a second vaccine comprising a live attenuated porcine reproductive and respiratory syndrome (PRRS) virus, for use in prophylactically treating a pig against an infection with PCV-2, an infection with Mycoplasma hyopneumoniae and an infection with PRRS virus, by associated separate injection of the first vaccine and the second vaccine into a tissue of the pig at a first and a second injection site respectively, wherein the first and second injection sites are at most 5 cm apart from each other.
Patent MX-2022014630-A (MX)
Title: Method and composition for treating cancer, killing metastatic cancer cells and preventing cancer metastasis using antibody to advanced glycation end products (age).
Inventor: GRUBER LEWIS S
IPC: A61K39/395
Filed: 2018-08-17
Abstract: A method of treating cancer, killing metastatic cancer cells, killing potentially- malignant neoplasm cells and/or preventing cancer metastasis comprises administering to a subject a composition comprising an anti-AGE antibody. A method of diagnosing metastatic cancer comprises detecting an immune complex comprising an anti-AGE antibody bound to a cell expressing an AGE modification.
Patent MX-2023000316-A (MX)
Title: Pharmaceutical compositions and methods for treating parkinson's disease.
Inventor: MODI NISARG
IPC: A61K31/352
Filed: 2021-08-13
Abstract: The current application relates to a topical pharmaceutical composition comprising at least one active agent selected from CBD and THC, solvent, surfactant, optional permeation enhancer, and optional adhesive/polymer. The topical composition is used for treating, preventing, or slowing the onset or progression of Parkinson's disease and/or related symptoms.