baber/WOPTO huggingface dataset:
Patent NZ-502423-A (NZ)
Title: Polynucleotide sequences, designated GS, in pathogenic mycobacteria and their use in vaccines
Inventor: TIZARD MARK
IPC: C07K14/35
Filed: 1996-12-23
Abstract: A polynucleotide comprising a gene region designated GS, which is found in Mycobacterium paratuberculosis (Mptb).  GS is also defined in Mycobacterium avium. subsp.silvatium (Mavs). The complete DNA sequence incorporating the positive strand of GS from an isolate of Mavs comprises 7995 nucleotides, including the core region of GS and adjacent transposable elements.  The DNA sequence of GS from Mptb comprises 4435 bp including the core region of GS (nucleotides 1614 to 6047 of GS in Mavs).  The DNA sequence of GS from Mptb is 99.4% homologous to GS in Mptb. There are eight open reading frames (ORFs) in GS.  Six of these, designated GSA, GSB, GSC, GSD, GSE and GSF are encoded by the core DNA region of GS which, characteristically for a pathogenicity island, has a different GC content from the rest of the microbial genome.  The proteins encoded by the ORFs in GS may be used in immunoassays of antibody or cell mediated immuno-reactivity for diagnosing infections caused by the mycobacteria.  Mutation or deletion of all or some of the ORFs in GS may be used to generate attenuated strains of Mptb, Mavs or Mtb with lower pathogenicity for use as living or killed vaccines in humans and animals.
Patent NZ-504711-A (NZ)
Title: Soft-pellet drug and process for the preparation thereof
Inventor: YOSHIDA HIROMITSU
IPC: A61K31/415
Filed: 1998-11-16
Abstract: A soft palletized drug composition comprising a drug substance having self-agglomerative properties and a sugar.  The drug composition is manufactured by dissolving or suspending a drug substance having self-agglomerative properties in a solution of a sugar, drying the solution or suspension to give a dry mixture, micronizing the dry mixture, and rolling the resulting finely micronized powder.
Patent NZ-506776-A (NZ)
Title: Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
Inventor: LI YONGAN
IPC: C07K16/18
Filed: 1999-03-18
Abstract: A DNA sequence as shown in SEQ ID NO:1 encodes a RIP-associated protein (RAP-2).  The RAP-2 protein is capable of modulating or mediating the intracellular activity of RIP in inflammation, cell survival or cell death pathways in which RIP is involved. Also described is a pharmaceutical composition comprising RAP-2 or a vector encoding RAP-2 and a method for treating tumor cells or HIV infected cells with a virus  vector carrying the sequence that encodes RAP-2 wherein the cells are not human cells in vivo.
Patent NZ-506901-A (NZ)
Title: Canned filled pet food comprising an outer tubular phase surrounding an inner cylindrical phase
Inventor: BAHAUX THIERRY
IPC: A23K1/18
Filed: 1999-02-18
Abstract: A canned pet food product made up of two phases (10,22). The product has an outer, tubular phase (10), which extends from the lower end to the upper end of the product and an inner phase (22), which extends from the lower end to the upper end of the product within the bore of the tubular outer phase (10).  Both phases are made up of an edible source of carbohydrate and protein. However, the inner phase (22) has an appearance different from that of the outer phase (10).
Patent NZ-508790-A (NZ)
Title: Heterocyclic compounds and methods to treat cardiac failure and other disorders
Inventor: MAVUNKEL BABU J
IPC: A61K31/4545
Filed: 1999-05-21
Abstract: Compounds of formula á and formula â are described, wherein the substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of a proinflammation response or a heart condition associated with cardiac failure.
Patent NZ-511449-A (NZ)
Title: Plasmid maintenance system for antigen delivery
Inventor: GALEN JAMES E
IPC: A61P31/04
Filed: 1999-12-02
Abstract: Disclosed generally is a Plasmid Maintenance System for the stabilization of expression plasmids encoding foreign antigens, and methods for making and using the Plasmid Maintenance System. It optimizes the maintenance of expression plasmids at two independent levels by: (1) removing sole dependence on balanced lethal maintenance functions; and (2) incorporating at least one plasmid partition function to prevent random segregation of expression plasmids, thereby enhancing their inheritance and stability. The Plasmid Maintenance System may be employed within a plasmid that has been recombinantly engineered to express a variety of expression products.
Patent NZ-512868-A (NZ)
Title: Methods for generating phosphorylation site-specific immunological reagents, polyclonal or monoclonal antibodies
Inventor: ANDERSON CARL W
IPC: C07K16/00
Filed: 2000-01-25
Abstract: A method for isolating polyclonal antibodies which specifically bind to a polypeptide phosphorylated at a particular amino acid comprising: (a) providing a composition comprising polypeptides containing a mimetic of the phosphorylated amino acid residue in a physiologically acceptable carrier, preferably the mimetic contains a non- hydrolyzable linkage from a carbon atom to a phosphate group wherein the linkage comprises a CF2 group; (b) immunising a non-human animal with the composition of step (a); (c) collecting and preparing serum or ascitic fluid from the immunised animal of step (b); (d) screening for the presence of antibodies specific for the phosphorylated polypeptides; and (e) when necessary, further enriching for antibodies specific for the phosphorylated polypeptide through conventional methods. Monoclonal antibodies may also be isolated by including steps of collecting B-cells from the immunised animal and generating hybridomas.
Patent NZ-518622-A (NZ)
Title: Method of producing collagen dough or emulsion from the gut of a ruminant mammal
Inventor: PHILLIPS ANDREW JAMES
IPC: C07K14/78
Filed: 2002-04-29
Abstract: A collagen dough or emulsion is described, wherein the collagen has been derived from the gut of a ruminant mammal. Also described is a process for forming the collagen dough, comprising harvesting and cleaning the gut (e.g. intestine) of a ruminant mammal such as of the bovine or ovine species, so that it is clear of the outer serosa (elastin).
Patent NZ-521318-A (NZ)
Title: Method and system to uniquely associate multicast content with each of multiple recipients
Inventor: WHITE MARK ANDREW GEORGE
IPC: H04N7/167
Filed: 2001-03-06
Abstract: A computer implemented method comprises: (a) Encrypting a copy of at least one part of a copy having a first watermark (220); (b) Encrypting a copy of at least one part of the content having a second watermark (230); and (c) Combining parts of the encrypted copy with the first watermark and parts of the encrypted copy with the second watermark in a manner unique for an individual client (108). The method protects file content when distributed across a network and allows for bandwidth economy and client identification by the content received.
Patent NZ-522638-A (NZ)
Title: New crystalline and amorphous form of a triazolo (4,5-D)pyrimidine compound
Inventor: BOHLIN MARTIN
IPC: A61P7/02
Filed: 2001-05-31
Abstract: A crystalline form of a triazolo (4,5-D) pyridimine compound represented by formula (I). Also covered are methods of preparing said compound and pharmaceutical compositions containing said compound.
Patent NZ-522881-A (NZ)
Title: An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
Inventor: ZHOU TONG
IPC: A61P25/00
Filed: 2001-05-02
Abstract: A purified antibody which specifically binds a TRAIL receptor DR5, wherein said antibody, has in vitro cell death-inducing activity in its soluble form at concentrations less than 1 ug/mL, in target cells expressing DR5, and in vivo tumorcidal activity in tumor cells expressing DR5, and wherein the antibody does not bind TRAIL receptor DR4, DcR1, or DcR2.
Patent NZ-527127-A (NZ)
Title: Lubricant composition
Inventor: DANIEL MERVYN FRANK
IPC: C10N40/00
Filed: 2002-02-08
Abstract: A lubricant composition comprising a base oil and one or more additives wherein the lubricant composition has a kinematic viscosity at 100 DEG C of more than 5.6 cSt, a cold cranking simulated dynamic viscosity at -35 DEG C according to ASTM D 5293 of less than 62 centiPoise (cP) and a mini rotary viscosity test value of less than 60000 cP according to ASTM d 4684, wherein the base oil has been obtained from a waxy paraffinic Fischer-Tropsch synthesized hydrocarbons and comprises at least 98% saturates, where the saturates fraction consists of from 10 to 40 wt% of cyclo-paraffins.
Patent NZ-528011-A (NZ)
Title: Aryl oxime-piperazines useful as CCR5 antagonists
Inventor: CLADER JOHN W
IPC: A61P17/06
Filed: 2002-03-27
Abstract: Aryl oxime-piperazine compounds of formula (I) useful as antagonists of the CCR5 receptor, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds and methods of preparing pharmaceutical formulations comprising one or more such compounds.
Patent NZ-529228-A (NZ)
Title: Trolley wheel assembly
Inventor: HIGGINS BRIAN JOHN
IPC: B60B33/00
Filed: 2002-03-28
Abstract: A trolley includes a front wheel assembly (12) and a rear wheel assembly both assemblies mounted on a trolley frame. The front wheel assembly includes a fixed wheel assembly (24) to aid control of the trolley. The front wheel assembly includes a pair of swivel casters (18) with the fixed wheel assembly disposed between the casters. The front wheel assembly is designed so that when the casters swivel from their orientation for forward travel, the fixed wheel assembly is caused to be lifted off the ground. The trolley also includes a camming device which is operative to lift the front wheel assembly off the ground when the trolley is moved into a nested configuration with a like trolley.
Patent NZ-529792-A (NZ)
Title: Small molecule antagonists of Bcl-2 family proteins
Inventor: WANG SHAOMENG
IPC: A61P31/04
Filed: 2002-05-30
Abstract: Disclosed is use of a gossypol compound selected from the group consisting of (±)-ethylgossypol, (-)-ethylgossypol, (+)-ethylgossypol, (±)- hemigossypolone, (-)-hemigossypolone, (+)-hemigossypolone, a Schiffs base of (±)- gossypol, a Schiffs base of (-)-gossypol, a Schiffs base of (+)-gossypol, a Schiffs base of (±)-gossypolone, a Schiffs base of (-)-gossypolone, a Schiffs base of (+)- gossypolone, a Schiffs base of (±)-gossypol acetic acid, a Schiffs base of (-)-gossypol acetic acid, a Schiffs base of (+)-gossypol acetic acid, a Schiffs base of (±)- ethylgossypol, a Schiffs base of (-)-ethylgossypol, a Schiffs base of (+)- ethylgossypol, a Schiffs base of(±)-hemigossypolone, a Schiffs base of(-)hemigossypolone, and a Schiffs base of (+)-hemigossypolone in the manufacture of a medicament for the treatment of cancer.
Patent NZ-533322-A (NZ)
Title: Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the use thereof as medicaments, in addition to a medicament containing same
Inventor: HOFMEISTER ARMIN
IPC: A61P9/12
Filed: 2002-11-20
Abstract: Compounds of formula (I), are extremely suitable as antihypertensives for reducing or preventing ischemically induced injuries, as medicaments for operative intervention for the treatment of ischemics of the nervous system, strokes and swelling of the brain, shocks, disturbed respiratory functions, for the treatment of snorers, as a laxative, as agents against ectopic parasites, for the prevention of gallstones, as antiatherosclerotic agents, agents against diabetic late complications, cancer, fibrotic diseases, endothelial dysfunctions, organ hypertrophia and hyperplasia. Said compounds are also inhibitors of the cellular sodium-proton-antiporters, they influence serum lipoproteins and can be used in the prophylaxis of and for the regression of atherosclerotic alterations.
Patent NZ-536780-A (NZ)
Title: Extruder die and cutter for filled food
Inventor: HUNTER THOMAS B
IPC: A21C11/16
Filed: 2003-06-11
Abstract: A die and cutter assembly (1) for an extruder includes an elongated extrusion member (9) having a first, open end (12) that is attachable in fluid communication with a first manifold and a second, closed end that is formed by a removable extrusion end cap (11). An extension (22) is formed on the elongated extrusion member (9). A filling passageway (20) is formed in a wall (10) of the extrusion member (9), which is attachable to a second manifold of the extruder. A first filling passageway extension (24) is in communication with and removably mounted to the filling passageway (20). The first filling passageway extension (24) is generally transverse to the filling passageway (20) and extends into the extension of the extrusion member (9). A cutter member (14) has an opened drivable end (15), an elongated cutter wall (16), and an opened cutter end (17) with a cutting surface (18) for cutting extrusion to a desired length.
Patent NZ-541735-A (NZ)
Title: Process for preparing pyridine-substituted amino ketal derivatives
Inventor: FLEMMING HANS-WOLFRAM
IPC: C07D213/53
Filed: 2004-01-27
Abstract: Disclosed is a process for preparing 1-(pyridinyl)-1,1-dialkoxy-1-aminoethane derivatives of the formula (I), where R1 and R2 are each independently (C1-C6)-alkyl, where the alkyl group may be straight-chain or branched, or where R1 and R2 together with the oxygen atoms form a cyclic ketal in which R1 and R2 together are a (C2-C4)-alkylidene group, and where the pyridine radical is substituted in the 2-, 3- or 4-position, which comprises: (a) converting acetylpyridine of the formula (V) using an aqueous solution of a hydroxylammonium compound or an aqueous solution of hydroxylamine, with the addition of an inorganic base comprising Mn+, to the acetylpyridlne oxime metal salt of the formula (IX) where n is 1 or 2 and Mn+ is an alkali metal or alkaline earth metal ion; (b) reacting the acetylpyridine metal salt of the formula (IX) with a solution of a p-toluenesulfonic acid derivative (X) containing a leaving group Y where Y is F, CI or Br, in a suitable solvent selected from an aliphatic or aromatic hydrocarbon which is unsubstituted or substituted by one or more substituents from the group (C1-C4)-alkyl, fluorine, chlorine and bromine, or a mixture of said aliphatic or aromatic hydrocarbons, to give the acetylpyridine tosyl oxime of the formula (XI), wherein the reaction proceeds continuously in a biphasic mixture of water and suitable solvent, optionally with the use of one or more phase transfer catalysts; and (c), converting acetylpyridine tosyl oxime of the formula (XI) without isolation to a compound of the formula (I) by metering compound (XI) to a mixture of an alkali metal alkoxide, an alkali metal hydroxide, an alkaline earth metal alkoxide or an alkaline earth metal hydroxide with an alcohol to a compound of the formula (I), where "alkoxide" means R1O- and/or R2O-, and where alcohol means R1OH and/or R2OH, and R1 and R2 are each as defined for the compound of the formula (I), and conducting process step (a) and (c) independently of each other batchwise or continuously.
Patent NZ-549997-A (NZ)
Title: Quinuclidine derivatives such as 4-[hydroxy(diphenyl)methyl]-1-{2-[(phenylmethyl)oxy]ethyl}-1-azoniabicyclo[2.2.2]octane bromide as muscarinic acetylcholine receptor antagonists
Inventor: LAINE DRAMANE I
IPC: A61K31/44
Filed: 2005-04-27
Abstract: Disclosed is the compound 4-[hydroxy(diphenyl)methyl]-1-{2-[(phenylmethyl)oxy]ethyl}-1-azoniabicyclo[2.2.2]octane bromide, a compound useful in the treatment of muscarinic acetylcholine receptor-mediated conditions such as chronic obstructive pulmonary disease, chronic bronchitis, asthma, chronic respiratory obstruction, pulmonary fibrosis, pulmonary emphysema and allergic rhinitis.
Patent NZ-552796-A (NZ)
Title: Crystalline form of biphenyl compound
Inventor: CHAO ROBERT S
IPC: A61K31/4709
Filed: 2005-08-15
Abstract: Disclosed is a crystalline 1,2-ethanedisulfonic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-5-methoxyphenylcarbamoyl)ethyl]piperidin-4-yl ester or a solvate thereof. Further disclosed is a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a compound as defined above and which optionally comprises a steroidal anti-inflammatory agent such as 6a,9a-difluoro-17a-[(2-furanylcarbonyl)oxy]-11b-hydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carbothioic acid S-fluoromethyl ester or a solvate thereof.
Patent NZ-552921-A (NZ)
Title: Gypsum plasterboard comprising at least a covering paper with a coating slip comprising plastic pigments, coating slip and related manufacturing method
Inventor: HEDMAN GORAN ERIK
IPC: D21H19/42
Filed: 2005-06-29
Abstract: Disclosed is plasterboard comprising at least one facing paper forming the exterior of the plasterboard and a coating slip deposited on said facing paper, characterised in that the coating slip contains plastic pigments as whitening agents. Also disclosed are a manufacturing process for said plasterboard and the use of a coating slip comprising plastic pigments to form the exterior of said plasterboard.
Patent NZ-552926-A (NZ)
Title: Rotary fan press with a tapered outlet
Inventor: DENDEL JOSEPH
IPC: B01D29/01
Filed: 2005-08-08
Abstract: A liquid extraction assembly for extracting liquid from a mass is disclosed. The extraction assembly includes a housing having an inlet and an outlet. The housing has a path between the inlet and the outlet. The housing is configured to have the mass forced into the inlet to move the mass from the inlet to the outlet. The housing includes two rotating screens adjacent to the path and defining opposite walls of the path. The outlet includes at least one pair of oppositely facing walls, which are fixedly tapered away from each other in an area of the rotating screens and in a direction of travel of the mass through the outlet. Each of the rotating screens includes a plurality of openings through the screens. Pressure from the mass forced into the inlet presses the mass against the rotating screens to thereby force at least a portion of liquid in the mass to pass through the openings of the rotating screens.
Patent NZ-562965-A (NZ)
Title: 3-aryloxy-8-aza-bicyclo[3.2.1]oct-6-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
Inventor: PETERS DAN
IPC: A61K31/46
Filed: 2006-06-07
Abstract: Disclosed is a compound of formula (I), or a tautomer, optical isomer, pharmaceutically acceptable salt, or mixture thereof, wherein Ra is hydrogen or an optionally substituted alkyl, Rb is an optionally substituted aryl, and wherein the optional substituents are as defined in the specification. Also disclosed is the use of the compound for treating a disease or disorder responsive to inhibition of monoamine neurotransmitter re-uptake in the central nervous system.
Patent NZ-565628-A (NZ)
Title: Heteroaryl-substituted diazatricycloalkanes, methods for its preparation and use thereof
Inventor: MAZUROV ANATOLY
IPC: A61K31/439
Filed: 2006-08-21
Abstract: Disclosed is a 3-pyridin-3-yl-1 ,5-diazatricyclo[5.2.2.0]undecane having a structure of the formula wherein: Y is either oxygen or sulfur, Z is either NR' or a covalent bond, A is either absent or a linker species selected from the group -CR' R"-, -CR' R"- CR'R"-, -CR'= CR'-, and -C2-, wherein R' and R" are defined in the specification, Ar is an aryl group, either carbocyclic or heterocyclic and Cy is a 5- or 6-membered heteroaromatic ring, wherein the junction between the azacycle and the azabicycle can be characterized by any of the various relative and absolute stereochemical configurations at the junction sites (e.g., cis or trans, R or S) and pharmaceutically acceptable salts thereof. Also disclosed is a composition comprising said undecane and the use in the treatment of pain, dementia, mania and depression.
Patent NZ-566315-A (NZ)
Title: A heater that is removably attached to a mounting base where electrical connection is automatic on mounting
Inventor: COOK DAVID LANGMAN
IPC: F24D13/00
Filed: 2008-02-29
Abstract: An electrically powered fan heater assembly in which the heater (7) is capable of being semi-permanently attached to a mounting base (2) is disclosed. An assembly comprises a mounting base (2) which includes an electrical assembly to which electrical wiring from an electrical power source can be terminated. The fan heater (7) includes a chassis (3) to receive component parts which comprise a heating unit. There is a means to enable the chassis (3) to be removably attached to the mounting base (2). While the chassis (3) is attached to the mounting base (2) the component parts of the heating unit is electrically connected to the power source. The electric connection is made when the heating unit is placed to the mounting base (2).
Patent NZ-570768-A (NZ)
Title: Glycosylated human G-CSF obtained from a transgenic chicken
Inventor: IVARIE ROBERT D
IPC: C07K14/535
Filed: 2007-02-20
Abstract: Disclosed is a composition comprising human granulocyte colony stimulating factor (G-CSF) having a poultry-derived glycosylation pattern wherein the glycosylation pattern is other than that of G-CSF produced in a CHO cell, and wherein the G-CSF is produced in an oviduct cell of a transgenic avian. The composition can be used to increase blood cell count in a patient.
Patent NZ-578057-A (NZ)
Title: Methods of screening for compounds that interfer with binding of COP-1 molecule to p53 molecule
Inventor: DORNAN DAVID
IPC: G01N33/574
Filed: 2004-10-14
Abstract: Disclosed are methods for screening for test compounds that interfere with the binding of a COP1 molecule to a p53 molecule. The methods and uses can further include detecting p53 expression. Also disclosed are mammalian cells that can be used for to screen for test compounds that interfere with the binding of a COP1 molecule to a p53 molecule. (62) Divided Out of 554438
Patent NZ-581389-A (NZ)
Title: Device and method for spectrographic analysis of vinefication products through freeze distillation
Inventor: JUHL HENRIK VILSTRUP
IPC: G01N1/40
Filed: 2008-06-04
Abstract: Disclosed is a device for the spectrometric assay of a liquid vinefication product (1) comprising an optical spectrometer (5) adapted to generate spectral information from the contents of a spectroscopic a sample cell (4); a data processor (10) having access to a chemometric calibration (11) developed from a spectral database (12) linking optical spectral information to compounds of interest in the liquid vinefication product and configured to process the same to generate an output result (13) indicative of the presence of one or more compounds of interest in the liquid vinefication product characterized in that the device further comprises a freezer unit (3) adapted for freeze distillation of the liquid vinefication product to generate a liquid distillate for analysis in the spectroscopic sample cell.
Patent NZ-587631-A (NZ)
Title: Timber joist, with two flanges in the form of poles joined together by a web
Inventor: THORNTON PATRICK
IPC: E04C3/17
Filed: 2009-01-28
Abstract: A timber joist 10 comprises first and second flanges connected together by a web 16 which is structurally integral with the flanges. Each flange comprises a timber pole with a substantially round cross section and a central core.