baber/WOPTO huggingface dataset:
Patent DE-69410121-T2 (DE)
Inventor: DUPLANTIER Allen
IPC: A61P27/16
Filed: 1994-11-18
Granted: 1998-09-03
Abstract: The compounds of the formula    <IMAGE>  I  and the pharmaceutically acceptable salts thereof; wherein X1, R1, R2, R3 and R4 are as defined herein, are inhibitors of PDE IV and the production of tumor necrosis factor. As such, they are active in the treatment of inflammatory diseases, shock etc.
Patent DE-69415141-T2 (DE)
Inventor: BONNER JAMES
IPC: C09J123/26
Filed: 1994-09-28
Granted: 1999-10-14
Abstract: PCT No. PCT/GB94/02114 Sec. 371 Date Jun. 14, 1995 Sec. 102(e) Date Jun. 14, 1995 PCT Filed Sep. 28, 1994 PCT Pub. No. WO95/09212 PCT Pub. Date Apr. 6, 1995A polyolefin-containing adhesive blend comprising: (A) 1 to 30 parts by weight of a graft copolymer having a polyolefin backbone grafted with 0.001 to 30% by weight of at least one polymerisable ethylenically unsaturated carboxylic acid or derivative thereof, (B) 70 to 99 parts by weight of a polyolefin provided that at least 5 parts by weight of (B) is (C) a polyethylene having a density of less than 930 kgm-3 wherein the graft copolymer (A) has been reacted with a compound(D) which has at least two primary or secondary amino groups at least one of which is a primary amino group, the sum of (A), (B) and (C) being 100 parts by weight. Multilayer structures comprising a polyolefin layer, a polyketone layer and an intermediate layer of the adhesive blend are also disclosed.
Patent DE-69415879-T2 (DE)
Inventor: HUOVILA JYRKI
IPC: D21F1/02
Filed: 1994-06-23
Granted: 1999-07-29
Abstract: The invention concerns a method in the regulation of the headbox of a paper machine/board machine. In the method, an additional flow (Q3.1,Q3.2...Q3.n) is introduced into the pulp suspension at different points across the width of the headbox, the concentration of said additional flow (Q3.1,Q3.2...Q3.n) being regulated. The concentration of the additional flow is regulated by means of a mixer unit (22), which comprises a displaceable distributor part (26), whereby, when the mixing ratio is being regulated, the flow resistances of the component flows (Q1,Q2) entering into the mixer unit (22) are adjusted by displacing the distributor part (26,260) of the mixer unit (22) in the chamber (F) of the mixer unit (22). <IMAGE>
Patent DE-69431128-T2 (DE)
Inventor: YAMADA TOSHIFUSA
IPC: H02M7/00
Filed: 1994-04-21
Granted: 2003-02-13
Abstract: A power transistor module comprises a circuit substrate, at least one pair of power transistor chips (Tr1, Tr2) mounted on said circuit substrate and each transistor chip having a first and a second main electrode and a control electrode, a flywheel diode (D1, D2) connected in antiparallel to said main electrodes of each power transistor chip, internal connection means for connecting one of said main electrodes of a first (Tr1) of said transistor chips to one of said main electrodes of the second transistor chip (Tr2) so as form the upper and lower arms of a bridge circuit, external connection terminals (C1, C2E1, E2, G1, G2) for connection to a main circuit, of which a first one (C1) is connected to the other one of said main electrodes of said first transistor chip (Tr1), a second one (C2E1) is connected to said internal connection means, and a third one (E2) is connected to the other one of said main electrodes of said second transistor chip (Tr2), and a first and a second auxiliary terminal (e1, e2) of which the first auxiliary terminal (e1) is connected to said internal connection means at a position same as the position at which the second external connection terminal (C2E1) is connected to it or nearer to said one main electrode of the first transistor chip (Tr1) than the latter, and the second auxiliary terminal (e2) is connected to the third external connection terminal (E2), wherein said internal connection means provides a predetermined wiring inductance (l1) between said one main electrode of the first power transistor chip (Tr1) on the one hand and the position at which said first auxiliary terminal (e1) is connected to it on the other hand. By this structure a surge generated at the time of the switching operation is suppressed, while at the same time, a balance is obtained in the switching characteristics between the upper and lower arms of the bridge when the internal wiring inductance l1 (l1=l2) is adjusted to have an appropriate value. <IMAGE>
Patent DE-69500497-T2 (DE)
Inventor: ENDERLEIN ROBBY
IPC: B07C3/08
Filed: 1995-01-27
Granted: 1998-01-29
Abstract: PCT No. PCT/EP95/01367 Sec. 371 Date Oct. 3, 1996 Sec. 102(e) Date Oct. 3, 1996 PCT Filed Apr. 12, 1995 PCT Pub. No. WO95/27673 PCT Pub. Date Oct. 19, 1995A suspension conveyor comprises two conveyor circuits which circulate in opposite directions. The circuits are arranged on opposite sides of an additional conveyor path, where the conveying directions of the path and circuits are the same at their point of coincidence. Roller devices for carrying objects (a, b, . . . , n), are entrained by a pushing or pulling mechanism of the conveyor circuits. A controllable switch arranged between the conveyor circuits, for transferring the objects individually from one of the conveyor circuits to the other, is adapted to transfer the objects selectively from the conveyor path to either of the conveyor circuits and vice versa. The switch is also adapted to selectively allow the objects to travel past the switch without leaving the respective conveyor circuit in which the objects are present. The suspension conveyor is additionally a sorting installation for sorting numerous different individually conveyed objects (a,b, . . . n). The additional conveyor path forms part of both conveyor circuits over at least an infinitesimal path portion at the location of the switch.
Patent DE-69507341-T2 (DE)
Inventor: SCHMIDT MANFRED
IPC: B22D11/112
Filed: 1995-10-16
Granted: 1999-08-26
Abstract: Flow control apparatus for enhancing inclusion float out in a continuous caster tundish comprising a dam positioned downstream from an impact pad and an energy source positioned between the dam and the exit nozzle of the tundish. The dam receives an incoming flood of molten metal released from the impact pad and redirects the flood of molten metal into multiple sub-flow currents which carry entrained inclusions toward a slag cover on the surface of the molten metal bath to enhance inclusion float out. The energy source provides means to restore kinetic energy to the sub-flow currents and increase the number of passes below the slag cover, thereby further enhancing inclusion float out.
Patent DE-69512925-T2 (DE)
Inventor: BREAULT GLORIA
IPC: C07C235/44
Filed: 1995-08-29
Granted: 2000-05-04
Abstract: PCT No. PCT/GB95/02030 Sec. 371 Date Feb. 21, 1997 Sec. 102(e) Date Feb. 21, 1997 PCT Filed Aug. 29, 1995 PCT Pub. No. WO96/06822 PCT Pub. Date Mar. 7, 1996The invention provides compounds of formula I: wherein A, B, D, X, R1, and R3 have any of the values defined in the specification, as well as N-oxides thereof, S-oxides thereof, pharmaceutically acceptable salts thereof, and in vivo hydrolizable esters and amides thereof, that are useful to relieve pain. The invention also provides pharmaceutical compositions as well as synthetic and therapeutic methods relating to such compounds.
Patent DE-69522699-T2 (DE)
Inventor: MATSUI SHUICHI
IPC: C09K19/42
Filed: 1995-10-13
Granted: 2002-07-04
Abstract: Liquid crystal compositions are provided which have a particularly excellent miscibility at low temperatures , properly large  DELTA n, and small V @  @  and viscosity while satisfying several characteristics required of liquid crystal composition for AM-LCD. Disclosed are liquid crystal compositions containing, as a first component, at least one compound expressed by general formula either (I-1) or (I-2), and containing, as a second component, at least one compound expressed by any one of general formulas (II-1) to (II-7) <CHEM>   <CHEM> wherein n is an integer of 1 to 10, Z<1> represents -CH2CH2- or single bond, X represents F or OCF3, Y represents H or F, and m is 0 or 1. The liquid crystal compositions of the present invention are useful as liquid crystal material for low voltage in several modes such as active matrix mode and STN mode.
Patent DE-69526456-T2 (DE)
Inventor: OUELLETTE EDWARD L
IPC: A21C3/10
Filed: 1995-08-09
Granted: 2002-11-21
Abstract: An apparatus for forming a sheet of material from a supply of the material, and for cutting portions of the material from the sheet of material, the apparatus including: a support, first and second rotatable rollers positioned adjacent each other to form a gap therebetween for receiving the material from the supply and outputting a sheet of the material, a drive for rotating the rollers and a cutter secured to the support and including an elongated member having an exterior surface configured to cut individual portions of the material from the sheet of material, the elongated member having opposite ends and a central portion; characterized by: the cutter being secured to the support with the central portion of the elongated member pressed against the front roller for cutting the sheet of material into the individual portions, the opposite ends of the elongated member each being journalled in a bearing and having a lift force applied thereagainst to press the central portion of the elongated member against the front roller, and wherein a bending moment is applied to each of the opposite ends of the elongated member to induce a camber in the elongated member and provide a uniform pressure across the interface of the central portion thereof and the front roller; whereby bowing of the cutter and resultant reduction in pressure between the elongated member and front roller is prevented.
Patent DE-69532684-T2 (DE)
Inventor: HECKMANN BERTRAND
IPC: A61P9/08
Filed: 1995-08-01
Granted: 2004-07-29
Abstract: PCT No. PCT/FR95/01033 Sec. 371 Date Jan. 31, 1997 Sec. 102(e) Date Jan. 31, 1997 PCT Filed Aug. 1, 1995 PCT Pub. No. WO96/04275 PCT Pub. Date Feb. 15, 1996The invention relates to the products of formula (I):    <IMAGE>  (I)  in which: R1=represents hydrogen, aryl, arylcarbonyl, arylthio, alkylcarbonyl, R2, R3 represent in particular halogen, mercapto, acyl, carboxy, nitro, cyano, amino, carbamoyl, R4, -OR4 with R4 representing in particular hydrogen, alkyl, alkenyl, alkynyl, acyl, amino, -(CH2)m1-S(O)m2-X-R10 with m1=0 to 4, m2=0 to 2, X represents a single bond or -NH-, -NH-CO-, -NH-CO-NH-, and R10 represents alkyl, alkenyl or aryl, and Y represents optionally substituted aryl, these products being in all isomer forms and salts, their use as medicaments.
Patent DE-69533676-T2 (DE)
Inventor: TE RIELE PETRUS
IPC: C12N15/85
Filed: 1995-07-26
Granted: 2005-12-01
Abstract: A mammalian cell having a mismatch repair-deficient phenotype is provided, where one or both alleles of a gene essential for mismatch repair, such as an Msh gene, are inactivated. Using this cell in a gene knock-out methodology advantageously allows efficient homologous recombination, even when the DNA sequences of the donor and recipient sequences diverge by significantly more than 0.6%.
Patent DE-69603652-T2 (DE)
Inventor: BRUNEL MARC
IPC: A61M5/24
Filed: 1996-05-02
Granted: 2000-04-20
Abstract: The procedure consists of forming a tubular body (101) from a flexible plastic material, equipped with finger grips (105) at one end and a lock (104) at the other, and fitting it with a tubular sleeve which can slide along the body and cover the needle (116), the sleeve having an inner locking member (111) to engage with the lock (104) on the body. The inside of the syringe body is fitted with a rigid pre-filled cylinder equipped with a needle and a plunger for performing the injection. Once the syringe has been used the outer sleeve is locked in its forward position, protecting the needle and preventing re-use.
Patent DE-69612013-T2 (DE)
Inventor: LIZARDI PAUL M
IPC: C12Q1/68
Filed: 1996-11-21
Granted: 2001-08-02
Abstract: Disclosed are compositions and a method for amplification of and multiplex detection of molecules of interest involving rolling circle replication. The method is useful for simultaneously detecting multiple specific nucleic acids in a sample with high specificity and sensitivity. The method also has an inherently low level of background signal. A preferred form of the method consists of an association operation, an amplification operation, and a detection operation. The association operation involves association of one or more specially designed probe molecules, either wholly or partly nucleic acid, to target molecules of interest. This operation associates the probe molecules to a target molecules present in a sample. The amplification operation is rolling circle replication of circular nucleic acid molecules, termed amplification target circles, that are either a part of, or hybridized to, the probe molecules. A single round of amplification using rolling circle replication results in a large amplification of the amplification target circles. Following rolling circle replication, the amplified sequences are detected using combinatorial multicolor coding probes that allow separate, simultaneous, and quantitative detection of multiple different amplified target circles representing multiple different target molecules. Since the amplified product is directly proportional to the amount of target sequence present in a sample, quantitative measurements reliably represent the amount of a target sequence in a sample. Major advantages of this method are that a large number of distinct target molecules can be detected simultaneously, and that differences in the amounts of the various target molecules in a sample can be accurately quantified. It is also advantageous that the DNA replication step is isothermal, and that signals are strictly quantitative because the amplification reaction is linear and is catalyzed by a highly processive enzyme.
Patent DE-69620632-T2 (DE)
Inventor: MERCIER ROLAND
IPC: B42F21/00
Filed: 1996-10-30
Granted: 2002-11-14
Abstract: The present invention pertains to a filing element such as a suspended file or file folder for the introduction of documents and an identification strip, characterized in that the identification strip exhibits at least one series of sites, each of which is identified by an alphanumeric labeling that is permanent and invariable for the totality of the elements of a filing system, with one of the sites of the series also having at least one colored identification labeling, with the choice of the labeling colors and the labeling site being specific to the given filing element.
Patent DE-69627159-T2 (DE)
Inventor: KHOURI K
IPC: A61F5/03
Filed: 1996-08-19
Granted: 2004-02-12
Abstract: An apparatus and method for enlargement of soft tissue, such as breasts or a penis, is comprised of a dome (12) configured to fit over the area of desired augmentation. The dome has a rim (34) with a surface area sized to prevent excessive contact pressure to the skin when a suction force of sufficient magnitude to cause enlargement of the soft tissue is applied to the soft tissue by the dome. A dome for applying a vacuum to a patient's skin surface is comprised of a generally rigid dome capable of withstanding a pressure differential, with a rim cushion (46) underlying the rim of the dome for supporting a rim from the patient's skin surface. The rim may be generally wider than the dome in order to distribute the attendant forces across a greater surface and avoid tissue damage. A sticky sole underlies the rim cushion and seals the rim cushion to the patient's skin to thereby preserve the vacuum within the dome.
Patent DE-69627355-T2 (DE)
Inventor: DENNY ALEXANDER
IPC: A61K31/555
Filed: 1996-08-19
Granted: 2004-02-12
Abstract: A method of treating neoplastic disease which comprises the steps of:     (a) administering to a patient in need of such treatment an effective amount of a radiation-activated cytotoxin prodrug (RACP) which has low toxicity, which can be reduced by reducing agents generated by the radiolysis of water (the equated electron and/or the hydrogen radical) and which, upon reduction, releases a sufficient amount of an effector of sufficient cytotoxic potency to kill tumour cells; and   (b) irradiating said tumour cells to reduce the prodrug which is present at the locus of said tumour cells to release said cytotoxic effector.   In preferred embodiments, the RACP is of formula (I), (VI), (VII) or (VIII).
Patent DE-69633635-T2 (DE)
Inventor: THIELE M
IPC: A61K31/70
Filed: 1996-10-25
Granted: 2006-03-09
Abstract: PCT No. PCT/US96/17240 Sec. 371 Date May 27, 1997 Sec. 102(e) Date May 27, 1997 PCT Filed Oct. 25, 1996 PCT Pub. No. WO97/15324 PCT Pub. Date May 1, 1997The present invention relates to a malondialdehyde-acetaldehyde adduct which acts as a specific immune-enhancing factor. In addition to its highly specific and immunogenic properties, the factor is highly fluorescent. It has an excitation frequency of about 398 nanometers and an absorbance of about 460 nanometers. The factor is also highly reactive and is also adducted to antigens including complex proteins, lipids, carbohydrates or DNA.
Patent DE-69705609-T2 (DE)
Inventor: VAEAENAENEN RAIMO
IPC: F23J15/00
Filed: 1997-04-11
Granted: 2002-05-08
Abstract: The invention relates to a method for generating hot gas, whereby hot gas (3) is being generated by means of a heating space (2), that is at least partially in connection with a liquid space (1), whereby at least to adjust the final temperature (T) of the generated hot gas cooling medium (4) is being mixed into the hot gas (3) after the heating space (2), when viewed in the flow direction(s) of the hot gas, such as in connection with an exhaust flow arrangement (5), that is connected to the heating space (2). The final temperature (T) of the generated hot gas (3) is being adjusted at least partially by mixing into the same at least by means of first mixing means (6a) vaporized medium (4a), such as water vapour or like, that has been vaporized from the liquid space (1), that is at least partially in connection with the hot gas (3), such as surrounding the heating space (2) and/or the exhaust flow arrangement (5). The invention relates to an apparatus functioning according to the method, also.
Patent DE-69706998-T2 (DE)
Inventor: PIERCE GLENN
IPC: A61L31/00
Filed: 1997-06-20
Granted: 2002-07-04
Abstract: Medical devices are coated with heparin and a heparin-binding growth factor-cytotoxic agent conjugate is bound to the heparin. The devices, including stents, are used to inhibit undesired cell proliferation or kill unwanted cells. A stent coated with heparin and bound with conjugate may be used to inhibit restenosis.
Patent DE-69709318-T2 (DE)
Inventor: NEWCOMBE CHARLES
IPC: B41J2/06
Filed: 1997-01-22
Granted: 2002-09-19
Abstract: An apparatus for ejecting material from a liquid has an ejection location 91) with an electrode (3). An electrical potential is applied to the ejection location electrode to form an electric field at the location together; liquid is supplied to the ejection location which contains the particulate material to be ejected from the ejection location. A secondary electrode (5, 8) is disposed adjacent to the ejection location and the voltage on the ejection location electrode is controllable so as to reduce the sensitivity of the head to influence by external electric fields.
Patent DE-69716249-T2 (DE)
Inventor: REYNOLDS S
IPC: F16D55/40
Filed: 1997-04-02
Granted: 2003-06-18
Abstract: A multi-disc brake (30,60) includes a piston housing (32,62) and attached torque tube (34,64) located about an axle (67,97). Axially adjacent the piston housing (32,62) is a brake actuator (40,70). In one embodiment, the piston housing (32) is located axially between an actuator member (59A) of the brake actuator (40) and a thrust sleeve (20) located about the axle sleeve (19) and abutting a wheel sleeve (16) engaging a wheel bearing assembly (12). In another embodiment, the actuator member (89A) can extend to engage a stationary portion (91) of the axle (97). Hydraulic actuation of the brake actuator (40,70) displaces axially the actuator member (59A,89A) against either a bushing (35) of the piston housing (32) or the stationary portion (91) of the axle (97) such that at least one of the piston housing (32,62) and torque tube (34,64) are compressed operatively in the axial direction by the brake actuator, thereby reducing torsional vibrational movement of the piston housing (32,62) and torque tube (34,64) about the axle (67,97).
Patent DE-69727924-T2 (DE)
Inventor: LOENNOE ANDERS
IPC: G01B7/16
Filed: 1997-04-24
Granted: 2005-03-10
Abstract: The invention relates to a device for measuring the shearing action in the core of a sandwich structure, for instance a hull. The device comprises a sensing means, e.g. a cylindrical rod, and a measuring instrument. The rod is adapted to be inserted into a cylindrical hole which is bored in the hull preferably perpendicular to the surface thereof so as to extend a distance into the core and which has a diameter corresponding to that of the rod. By means of the measuring instrument, an angle between the rod and a reference plane is measured, which is determined by three points on the surface of the hull or the change of this angle when the hull is subjected to a change in load. This angle can be converted into a measure of the current shearing load.
Patent DE-69728891-T2 (DE)
Inventor: FREDERIKSEN EYVIND
IPC: F01N3/28
Filed: 1997-09-30
Granted: 2005-04-28
Abstract: The device for silencing a flow of gas, e.g. an exhaust gas, comprises at least one acoustic chamber (l,2,3) through-flowed by gas, at least one inlet pipe (6) for leading gas into the device and at least one pipe or passage (4,12,13) interconnecting two chambers or a chamber and an exterior environment or chamber. The device includes cross-sectional area transitions between pipes or passages (4,6,12,13) and the chambers (l,2,3) so that the sound attenuation achieved by the device is high while the pressure drop across the silencer is low and that high attenuation at low characteristic frequencies of flow systems comprising the device are obtained. One or more diffusers (l0a,12a,13a) for diffusing at least part of the gas flow, e.g., at the inlet to the chambers may be included in the device. One or more monolithic bodies or catalysers may be included in the device. Devices with curved or helical passages allowing a low natural frequency and embodiments having resonance chambers attenuating at selected frequencies may be included.
Patent DE-69730045-T2 (DE)
Inventor: MCMICHAEL JOHN
IPC: A61K31/417
Filed: 1997-10-16
Granted: 2005-07-21
Abstract: The present invention relates to a treatment for patients having urinary incontinence by administering a composition comprising histamine, serotonin or a combination thereof in an amount effective to alleviate symptoms of urinary incontinence.
Patent DE-69736132-T2 (DE)
Inventor: KURPPA JUHANI
IPC: A23L27/14
Filed: 1997-01-20
Granted: 2007-01-11
Abstract: The invention relates to the use of flavonoids as flavoring substances and/or as salt substitutes. A mixture of several flavonoids such as from onion, apple and tea are mixed to form a composition. The flavonoid preparation may be used as a general flavouring substance and as a salt substitute in home cooking as well as in food industry.
Patent DE-69804615-T2 (DE)
Inventor: KNUDSEN FINN
IPC: B31C11/04
Filed: 1998-07-01
Granted: 2002-10-24
Abstract: In a method of making a carton tube (8) by winding a carton strip (3) with a layer of glue (not shown) onto a mandrel (7),  the new feature is that the carton strip (3) has previously been coated with a layer of glue of a kind, that can be changed from an inactive into an active state and vice versa, the glue being in the inactive state until passing through an activating unit (5) situated close to the winding-on point (9) (or even at these points or downstream of it, if thermal activation is used). By proceeding in this manner, spillage of glue on the equipment used for carrying out the method is avoided, thus reducing the need for supervision. <IMAGE>