baber/WOPTO huggingface dataset:
Patent CA-2221567-A1 (CA)
Inventor: LENTING PETRUS JOHANNES
IPC: A61K38/00
Filed: 1996-06-12
Abstract: La présente invention concerne des peptides biologiquement actifs qui inhibent spécifiquement le processus de coagulation sanguine dépendant du facteur IX. Ces peptides sont basés sur un motif spécifique qui représente une séquence du facteur VIII (acide aminé 1811-1818) impliqué dans la liaison au facteur IX activé, ainsi qu'au zymogène intact du facteur IX. La liaison de ces peptides au facteur IX ou à des dérivés activés de celui-ci inhibe efficacement la formation du complexe avec le facteur VIII. Ces peptides interfèrent ainsi de manières spécifique avec le processus de formation de la thrombine dépendant du facteur IX, tout en n'exerçant aucune influence sur les autres processus hémostatiques. Grâce à cette spécificité très particulière, les peptides de cette invention permettent de réaliser de nouvelles compositions pharmaceutiques très utiles contre les troubles thrombotiques.
Patent CA-2221749-A1 (CA)
Inventor: MILLER WILLIAM J
IPC: G02F1/35
Filed: 1996-05-23
Abstract: Commutateur compact monolithique de Mach-Zehnder conçu de telle façon qu'un des trajets de guides d'ondes (69, 70) entre les coupleurs d'entrée et de sortie (67, 68) contient un matériau présentant une non linéarité résonante, ce qui modifie son indice de réfraction quand une puissance de pompage se propage à travers ledit matériau. Chacun des trajets de guides d'ondes (69, 70) possède une constante de propagation différente, ce qui soumet le signal lumineux à un temps de propagation différent dans chaque trajet, quand aucune puissance de pompage se propage à travers le trajet non linéaire en éléments des terres rares. Un signal d'entrée appliqué à l'entrée (71, 72) du commutateur apparaît au niveau d'une première borne de sortie (73, 74), quand la puissance de pompage ne se propage pas à travers le trajet non linéaire et apparaît au niveau d'une deuxième borne de sortie (73, 74), quand la puissance de pompage est appliquée au trajet non linéaire. La commutation s'effectue à des niveaux relativement bas de la puissance de pompage.
Patent CA-2224430-A1 (CA)
Inventor: KOTSUGAI TAKESHI
IPC: G01N33/577
Filed: 1996-05-29
Abstract: A colloidal gold immunoassay method for detecting a substance to be examined wherein the reaction mixture contains metal salt(s) selected from the group consisting of sodium fluoride, potassium fluoride, lithium fluoride, sodium iodide, potassium iodide, lithium iodide, magnesium iodide, sodium bromide, potassium bromide, lithium bromide, magnesium bromide, lithium chloride, magnesium chloride, sodium nitrate, potassium nitrate, lithium nitrate, magnesium nitrate, sodium sulfate, potassium sulfate, lithium sulfate, magnesium sulfate, sodium formate, potassium formate, lithium formate, magnesium formate, sodium acetate, potassium acetate, lithium acetate, magnesium acetate and mixtures of two or more of the same which have been dissolved in the immunoreaction system. In this method, the metal salt contributes to the extremely distinct color development of the colloidal gold.  In the case of a specimen at a concentration in the vicinity of the detection limit, in particular, the positivity can be more clearly distinguished from the negativity with the naked eye, which facilitates the judgement.
Patent CA-2227409-A1 (CA)
Title: Compact moisture sensor with collimator lenses and prismatic coupler
Inventor: TEDER REIN S
IPC: G01N21/17
Filed: 1997-05-20
Abstract: A compact rain sensor (10) for mounting on the inner surface (30) of a windshield (18) includes collimator lenses (64, 66) and a detachable prismatic coupler (38) to facilitate the mounting of infrared emitters (56) and detectors (58) on a circuit board (26) which is positioned parallel to the inner surface of the windshield and has signal processing circuitry (80 A-D) as well. A thin optical coupler is adhesively secured to the windshield and a sensor housing (28) is detachably secured about the outer edges of the coupler.
Patent CA-2229933-A1 (CA)
Title: Method and apparatus for coating a decorative workpiece
Inventor: CHIAROTTO OSCAR
IPC: B28B11/04
Filed: 1998-02-19
Abstract: A method and apparatus is provided for applying a plaster-like coating material under pressure to the decorative exposed surface of a moulded workpiece. The apparatus comprises a means for advancing a workpiece in a straight horizontal plane through said apparatus, means for engaging a workpiece to constrain movement as it passes through said apparatus, and means for applying a plaster-like coating material to a decorative surface of an advancing workpiece, wherein the coating means also has a means for providing a desired controlled thickness of a coating material onto the decorative exposed surface of an advancing workpiece. Both the method and apparatus provide on a consistent basis, a smooth coating with a controlled thickness tightly bonded to the entire exposed decorative surface of a workpiece. The method and apparatus avoid the problems of having air bubbles, cracks or an uneven thickness of coating material left on the coated workpiece. The method and apparatus provide a simple, efficient, cost effective and reliable means for applying a plaster-like coating to the exposed decorative surface of a workpiece such that they can be coated and used widely on a commercial scale in the construction industry.
Patent CA-2231837-A1 (CA)
Inventor: NADIZADEH HOSSAIN
IPC: C07D305/14
Filed: 1996-09-13
Abstract: L'invention se rapporte à des taxanes renfermant des groupes fonctionnels à effet radiosensibilisant, à affinité électronique, ainsi qu'à leurs préparations pharmaceutiques et aux procédés de fabrication et d'utilisation de cette nouvelle classe de substances qui augmentent considérablement la sensibilité des cellules tumorales aux radiations.
Patent CA-2232668-A1 (CA)
Title: Novel derivatives of cyclodepsipeptide pf1022 substance
Inventor: IINUMA KATSUHARU
IPC: C07D273/00
Filed: 1996-09-20
Abstract: Novel PF1022 derivatives which are cyclic depsipeptides represented by general formula (I) or their salts are useful as a vermicide in the prevention or treatment of vermination.
Patent CA-2235360-A1 (CA)
Title: Nouvelles chimiokines utilisees pour mobiliser des cellules souches
Inventor: KREIDER BRENDT L
IPC: A61P7/06
Filed: 1996-10-23
Abstract: Cette invention se rapporte à de nouvelles chimiokines utilisées pour mobiliser des cellules souches ainsi qu'à des procédés de mobilisation de cellules souches.
Patent CA-2235829-A1 (CA)
Title: Packet switched radio channel congestion control
Inventor: ANDERSSON MAGNUS
IPC: H04L12/56
Filed: 1996-10-21
Abstract: A method and system for controlling congestion on a packet switched radio channel (PRCH) (128, 130, 132) is disclosed. A PRCH congestion control function (418a, 418b, 418c, 418d) determines if the average time delay for packet calls on the PRCH (128, 130, 132) is within a delay alarm level. If the average time delay is not within the delay alarm level, it is then determined which packet calls to expel from the PRCH (128, 130, 132) in order to decrease the average time delay. The determination of congestion may be made for each of the uplink and downlink of a PRCH (128, 130, 132) seaprately, or, on the combined uplink and downlink of the PRCH (128, 130, 132).
Patent CA-2241253-A1 (CA)
Title: Dispositif d'analyse immunologique automatique
Inventor: KAWAI YOSHIO
IPC: G01N35/02
Filed: 1997-10-21
Abstract: Dispositif d'analyse immunologique automatique, dans lequel des ensembles de tubes de réaction sont disposés entre les pourtours extérieur et intérieur d'une tourelle de réaction, et des anneaux magnétiques pivotants à montage magnétique sont intercalés entre les tubes. La séparation effective éléments liés/éléments libres et l'agitation d'un réactif de particules magnétiques fines sont effectués en décalant les tubes et les aimants d'un cran au bout de chaque période de référence, un examen photométrique étant ensuite réalisé au moyen d'une méthode de chimioluminescence. L'emploi d'un procédé utilisant un embout individuel pour la distribution de l'échantillon et du réactif, comportant un changement d'embout à chaque opération permet d'éviter la contamination mutuelle. Des pompes et des ajustages individuels sont en outre utilisés pour un liquide agité et un liquide injecté.
Patent CA-2243578-A1 (CA)
Title: High affinity nucleic acid ligands of complement system proteins
Inventor: GOLD LARRY
IPC: C12Q1/68
Filed: 1997-01-30
Abstract: Methods are described for the identification and preparation of high affinity nucleic acid ligands to Complement System Proteins.  Methods are described for the identification and preparation of high affinity nucleic acid ligands to Complement System Protein, C1q.  Included in the invention are specific RNA ligands to C1q identified by the SELEX method.
Patent CA-2244282-A1 (CA)
Inventor: GALIAN FRANCOIS
IPC: F25B41/04
Filed: 1998-09-15
Abstract: Le dispositif frigorifique comporte, dans un circuit frigorifique classique, en plus du classique capilaire 1, un second organe de détente comme le capillaire 2, qui prélève une partie des gaz haute pression saturés lorsque les conditions de fonctionnement réelles sont plus élevées que les conditions de fonctionnement nominales. Application à la réalisation de climatiseurs d'air ambiant ou de groupes frigorifiques.
Patent CA-2245055-A1 (CA)
Title: Amidation of pyridines
Inventor: VOGT PETER
IPC: C07D213/61
Filed: 1990-01-30
Abstract: It has been found that pyridine-2-carboxamides of the formula (see fig.I) wherein R signifies amino or a residue convertible into amino, and pharmaceutically usable acid addition salts of that carboxamide in which R signifies amino can be manufactured in a simple manner and in good yield by reacting 2,5-dichloropyridine in the presence of a palladium-phosphine catalyst with an alkyne of the formula R1-C~CH                      III   wherein R1 signifies hydrogen, lower-alkyl, trimethylsilyl or the group -(R2)(R3)-COH and R2 and R3  each independently signify hydrogen or lower-alkyl or together signify cyclopentyl or cyclohexyl, oxidizing the resulting alkyne to give 5-chloropyridine-2--carboxylic acid and reacting this acid or a reactive functional derivative thereof with an amino compound of the formula (see fig. I) or with carbon monoxide and an amino compound of formula VI or with carbon monoxide and a lower alkanol which is optionally mixed with water and reacting the resulting acid or the resulting ester with an amino compound of formula VI. The compounds of formula I in which R signifies amino are known, reversible and highly active MAO-B inhibitors.
Patent CA-2248133-A1 (CA)
Title: Absorbent article having a breathability gradient
Inventor: ODORZYNSKI THOMAS WALTER
IPC: A61F13/49
Filed: 1997-03-14
Abstract: An absorbent article includes a garment facing surface which includes a first zone of vapor permeability which defines a water vapor transmission rate of from about 100 to about 2500 g/sq.m/24 hr and a second zone of vapor permeability which defines a water vapor transmission rate of at least about 3000 g/sq.m/24 hr. The article may include a substantially liquid impermeable, vapor permeable backsheet, a liquid-permeable topsheet positioned in facing relation with the backsheet, an absorbent body located between the backsheet and topsheet, and a vapor permeable barrier layer located between the absorbent body and the backsheet. The barrier layer is smaller in size than the backsheet. In such a configuration, the first zone of vapor permeability comprises the portion of the backsheet which overlays the barrier layer, and the second zone of vapor permeability comprises the portion of the backsheet which extends beyond the barrier layer.
Patent CA-2248184-A1 (CA)
Inventor: STURLA JEAN-MICHEL
IPC: A61K8/00
Filed: 1997-02-19
Abstract: La présente invention a trait à une composition cosmétique pressurisée en aérosol pour le traitement des matières kératiniques, en particulier des cheveux, comprenant (a) un jus comprenant au moins un polymère fixant, au moins 5 % en poids par rapport au poids total de la composition pressurisée d'une silicone arylée non volatile et (b) au moins un propulseur, ainsi qu'au procédé de traitement des matières kératiniques à l'aide de cette composition.
Patent CA-2249323-A1 (CA)
Inventor: LIU DASHAN
IPC: C07K1/04
Filed: 1997-03-21
Abstract: L'invention a pour objet une bibliothèque de substances et de compositions distinctes, de formules générales R-P-S-L et P-S-L, représentant respectivement des lipoglycopeptides liés par un support solide et des lipoglycopeptides libres. L'invention se rapporte également à des procédés combinatoires de préparation de différentes bibliothèques et à un test servant à déterminer l'activité biologique de membres sélectionnés dans cette bibliothèque. Un mode de réalisation spécifique concerne des inhibiteurs de la synthèse de peptidoglycane bactérien.
Patent CA-2250130-A1 (CA)
Inventor: CRISP DAVID JOHN
IPC: A47B88/48
Filed: 1997-03-27
Abstract: The invention relates to a modular storage system, comprising a plurality of storage receptacles (2), and a frame (1') defining a plurality of openings (3) each for receiving a respective receptacle, each opening (3) and receptacle (2) having releasably engageable means (4, 5) whereby a receptacle (2) can take up two positions with respect to the frame (1') without disturbing another receptacle (2) of the system (1).
Patent CA-2252609-A1 (CA)
Title: Polyol composition
Inventor: SCHWARZ EUGEN
IPC: A61K9/20
Filed: 1997-04-10
Abstract: The invention relates to a composition obtainable by co-spray drying or co-fluidised bed granulation, essentially consisting of at least two polyols and possibly one binder with a content of over 80 wt.% of at least one non-hygroscopic polyol, and its use as an auxiliary for the production of tablets.
Patent CA-2252954-A1 (CA)
Title: Winding unit particularly for winding yarns
Inventor: BERT PAOLO
IPC: B65H67/048
Filed: 1998-12-01
Abstract: A winding unit, particularly for winding yarns, includes a winding head provided with a device for guiding and cutting a yarn and two supports (11, 13, 19, 21). Each support is adapted to rotatably support a cardboard tube (25) which is adapted to wind the yarn in order to form a bobbin. The head has two winding positions and each support has a position for supporting the winding tube for winding the yarn and a disengagement position for unloading the full bobbin and loading a new tube.
Patent CA-2252987-A1 (CA)
Inventor: MILL PETER
IPC: F24F1/02
Filed: 1991-11-08
Abstract: An air distribution unit for mounting in the wall or floor of a room having a plenum space behind said wall or floor, comprises a housing having an air inlet for communication with the plenum space and an air outlet; a blower between the air inlet and air outlet for drawing air from the plenum space and exhausting it through the air outlet into the room; and a grille assembly mounted over the air outlet.  The grille assembly has aerodynamically profiled air distribution channels which may be circumferentially disposed, extending between the upper and lower surfaces thereof.  The air distribution channels open out onto the upper surface of the grille assembly at a shallow angle in a radially outward direction so that air flowing out of said channels is directed outwardly at an angle of between about 15° and 45° to the plane of the grille assembly.  A person sitting above the unit sits in a localized pocket of mainly fresh air without experiencing draughts or discomfort.
Patent CA-2255084-A1 (CA)
Title: Picture card
Inventor: SANTORSOLA ALAN JAMES
IPC: G09F11/23
Filed: 1997-05-16
Abstract: A picture card (9) including a front card (11), a back card (10), a first transparency (14) and a second transparency (18). First and second transparencies are rotatably secured together by means of grommet (20) and second transparency (18) is mounted to back card (10). First transparency (14) preferably includes an image similar to that of second transparency (18), whereby first transparency (14) can be rotated to align its image with the image of second transparency (18).
Patent CA-2257096-A1 (CA)
Inventor: POTHIER FRANCOIS
IPC: C12N15/90
Filed: 1997-05-30
Abstract: La présente invention concerne des produits de recombinaison d'ADN destinés à améliorer la transgénèse ou l'intégration génomique d'un fragment d'ADN déterminé dans l'ADN nucléaire d'une cellule eucaryote. Les produits de recombinaison d'ADN de la présente invention rendent la procédure plus efficace en accélérant la vitesse d'intégration génomique d'un fragment d'ADN. Une fois intégrés dans l'ADN de la cellule hôte, les produits de recombinaison d'ADN peuvent constituer un moyen de criblage des cellules transgéniques. On décrit également un moyen d'intégration plus grande ainsi qu'un procédé permettant de cribler les cellules transgéniques à l'aide desdits produits de recombinaison d'ADN.
Patent CA-2257225-A1 (CA)
Title: Membrane incorporation of texaphyrins
Inventor: MAGDA DARREN
IPC: A61K47/48
Filed: 1997-06-04
Abstract: Compositions having a texaphyrin-lipophilic molecule conjugate loaded into a biological vesicle and methods for imaging, diagnosis and treatment using the loaded vesicle are provided. For example, liposomes or red blood cells loaded with a paramagnetic texaphyrin-lipophilic molecule conjugate have utility as a blood pool contrast agent, facilitating the enhancement of normal tissues, magnetic resonance angiography, and marking areas of damaged endothelium by their egress through fenestrations or damaged portions of the blood vascular system. Liposomes or cells loaded with a photosensitive texaphyrin-lipophilic molecule conjugate can be photolysed, allowing for a photodynamic therapy effect at the site of lysis. Availability of red blood cells loaded with a photosensitive texaphyrin-lipophilic molecule conjugate provides a method for delivering a photodynamic therapeutic agent to a desired site with a high concentration of oxygen. By presenting the agent in this way, it is expected that a patient will experience less toxicity.
Patent CA-2258185-A1 (CA)
Title: Wire clamping collar
Inventor: DETABLE PASCAL
IPC: F16L33/02
Filed: 1997-07-01
Abstract: A clamping collar (10) constituted by a semi-rigid wire that is rolled up to form at least one turn (11) with a first end (12) thereof being provided with a hook (16) extending transversely to the plane of the turn and with a second end (14) thereof being folded back outwardly to form an extension (26) lying substantially in the plane of the turn. The extension (26) includes a fastening fold (28) forming a setback going towards the center of the turn, and it also includes a pre-fastening fold (32) situated between that end (24) of the extension (26) which is connected to the turn (11) and the fastening fold (28), said pre-fastening fold being analogous to the fastening fold.
Patent CA-2259136-A1 (CA)
Title: Pituitary differentiation factor and methods of use thereof
Inventor: PLATICA OVIDIU
IPC: A61P35/00
Filed: 1997-07-09
Abstract: The present invention is directed to pituitary differentiation factor (PDF), a pituitary factor that is capable of differentiating cells including breast cancer and prostatic cancer cells. Isolated nucleic acids encoding PDF and related vectors and host cells are also provided. Restoration of differentiating ability to malignantly transformed cells provides a modality of cancer therapy. The isolated and purified PDF of the invention is accordingly useful in the treatment of breast and prostatic cancer.
Patent CA-2260781-A1 (CA)
Title: Needleless connector
Inventor: WHITE JASON J
IPC: A61M39/02
Filed: 1998-05-20
Abstract: A connector (10) is provided which utilizes a resealable pre-slit septum valve (28). Septum (28) is resiliently restrained relative to housing (26) with septum (28), and housing (26) configured to accept a standard male luer lock (13) having luer tip (18) which penetrates septum (28) through resealable opening (44) to extend within housing (26), and luer locking flange (20) of luer lock (13) extending about housing (26). The septum (28) includes disk shaped upper portion (38) covering opening (44), lower portion (40) spaced from housing (26) and extending downward from disk shaped portion (38) into passageway (36) defined by housing (26), and annular skirt (52) to attach septum (28) to housing (26). Connector (10) exhibits satisfactory leak pressure after multiple connections and disconnections to luer lock (13) and long periods of indwell of luer tip (18).
Patent CA-2261948-A1 (CA)
Title: A process and composition for detergents
Inventor: HALL ROBIN GIBSON
IPC: C11D11/00
Filed: 1997-07-23
Abstract: A process for making a detergent composition comprising: i) admixing a detergent surfactant and an acid source to form a surfactant/acid mixture; and ii) forming an agglomerated surfactant/acid mix.
Patent CA-2262229-A1 (CA)
Inventor: FRITSCHE GREGOR
IPC: A61G15/16
Filed: 1999-02-17
Abstract: A curing device for light-induced curing of dental materials includes a hand-held apparatus containing a light source whereby the hand-held apparatus is pistol-shaped and comprises a main body and a grip connected to the main body. A cable connects the grip of the hand-held apparatus to a supply station. A support for receiving the hand-held apparatus is provided. The support is detachably connected to the supply station or a stand such that the support in which the hand-held apparatus is received is storable at the supply station or separate from the supply station.
Patent CA-2262583-A1 (CA)
Inventor: DUBUC PAUL C
IPC: B60P3/14
Filed: 1997-07-24
Abstract: A mobile unit (1) for fabricating solid surface construction materials is provided, as is a method of use therefor. The mobile unit is equipped with climate control units (23, 23a) fabrication equipment (24) and other environment control equipment and is brought directly to a worksite. Therefore, solid surface construction materials can be fabricated onsite, instead of at a remote fabrication shop. In the fabrication process according to the present invention, dimensional information is laid out directly onto the solid surface material stock. This eliminates the frequently inaccurate use of a temporary template, as in the known art.
Patent CA-2263002-A1 (CA)
Title: A water treatment cartridge and a water filter jug fitted with such a cartridge
Inventor: ROBINSON THOMAS
IPC: C02F1/00
Filed: 1997-08-06
Abstract: A drinking water treatment cartridge comprises a cup-shaped receptacle (49A) for containing water treatment particles and a closure (47A) which may be irreversibly snap-fitted thereon or welded thereto. The closure (47A) has a slotted skirt portion (50A) which surrounds a circumferential array of mesh covered apertures (57A, 57B) in a neck portion (55A) of the receptacle (49A). There are mesh covered slots in a domed crown portion of the closure (47A) and there is a mesh covered outlet aperture in the base of the receptacle (49A). Each mesh is integrally moulded with the surrounding structure by which it is supported.
Patent CA-2265251-A1 (CA)
Inventor: SHAN BEI
IPC: C12Q1/68
Filed: 1997-09-02
Abstract: L'invention concerne des procédés et des compositions destinés au criblage d'agents pharmacologiques régulant l'expression génétique chez les mammifères. Un dosage effectué à titre d'exemple consiste à: (a) mettre en contact une cellule mammalienne comprenant un mutant par choc d'un allèle endogène ciblé codant pour un marqueur d'expression génétique, comme indiqué dans le schéma 1, l'expression du marqueur étant régulée par les séquences de régulation d'expression génétique de l'allèle endogène, avec un agent candidat dans des conditions telles que, sans la présence de l'agent, le marqueur est exprimé à un premier niveau d'expression; et (b) mesurer l'expression du marqueur afin d'obtenir un deuxième niveau d'expression, dans lequel une différence entre le premier et le deuxième niveau d'expression indique que l'agent candidat module l'expression génétique.