baber/WOPTO huggingface dataset:
Patent DE-69807204-T2 (DE)
Inventor: DUPUIS CHRISTINE
IPC: C08G18/48
Filed: 1998-12-23
Granted: 2003-08-07
Abstract: The invention concerns cosmetic compositions containing, in a cosmetically acceptable support, as thickening system: (A) at least a non-anionic associative polyurethane and (B) at least an anionic polymer comprising at least a fatty chain monomer unit with fatty chain.
Patent DE-69820614-T2 (DE)
Inventor: HEAD CLIFFORD
IPC: A61P11/06
Filed: 1998-05-29
Granted: 2004-09-30
Abstract: Tyrosine derivatives of formula (1) are described: in which R is (1) a group R1X1- where R1 is an optionally substituted alkyl or aromatic group, and X1 is a covalent bond or a -(CH2)n- [where n is an integer 1 or 2], -C(O)-, -CH2C(O)-, -NHC(O)-, -CH2NHC(O)-, or -SO2- group, or (2) a group (Hal1)3CSO2-, where Hal1 is a fluorine or chlorine atom; R2 and R3, which may be the same or different, is each a hydrogen or halogen atom or an alkyl, alkoxy, hydroxyl or nitro group; Alk is an alkylene chain; m is zero or an integer 1; R4 is a hydrogen atom or a methyl group; R5 is a group -(CH2)pCO2R8 where p is zero or an integer 1 and R8 is a hydrogen atom or an alkyl group; R6 is a hydrogen atom or an alkyl group; Y is a sulphur atom or a -S(O)q- group where q is an integer 1 or 2; X2 is a -C(O)-, -C(O)O-, -CONH- or -S(O)2- group; R7 is an optionally substituted alkyl group or an aryl or aralkyl group; and the salts, solvates and hydrates thereof. The compounds are able to inhibit the binding of  alpha 4 integrins to their ligands and are of use in the prophylaxis and treatment of immune or inflammatory disorders.
Patent DE-69820878-T2 (DE)
Inventor: CONNOR FREDERICK
IPC: A61F11/08
Filed: 1998-01-20
Granted: 2004-10-14
Abstract: An earplug includes an electro-magnetically detectable material comprising an alloy of copper with at least one other metal, especially an alloy of copper and tin.
Patent DE-69821060-T2 (DE)
Inventor: STEEBY JON A
IPC: B60W10/11
Filed: 1998-08-06
Granted: 2004-11-11
Abstract: A partially automated transmission system (100) and method for controlling same is provided. The system includes a manually shifted splitter-type transmission (10) having a splitter section (14) and a manually shifted main section (12). The splitter section is controlled by a splitter actuator (116) under control from a system ECU (146). The operator is provided with a selector (120) for selecting upshifts and downshifts. Preferably, shifting in the upper group of ratios (A (9/10)) is fully automatic. <IMAGE>
Patent DE-69823535-T2 (DE)
Inventor: VESA JOUKO
IPC: E06B7/23
Filed: 1998-10-22
Granted: 2005-04-07
Abstract: A seal attached to a door frame for mating engagement with a door. The seal including a first side for sealing engagement with a door edge, and a second side for sealing engagement with the door outer surface. The seal moves relative to the door from the door open position, where the seal first side is disposed at a first spaced apart distance from the door frame edge surface; to the door closed position, where the door moves the seal first side closer to the door frame edge surface. The seal further moves relative to the door from the door open position, where the seal second side is not disposed adjacent to the door outer surface; to the door closed position where the seal second side is disposed adjacent to the door outer surface and in covering relation to the door outer surface.
Patent DE-69828017-T2 (DE)
Inventor: REINKE MICHAEL J
IPC: F24H3/10
Filed: 1998-08-27
Granted: 2005-04-07
Abstract: A clamshell heat exchanger (10) is provided for use in a heating apparatus including a burner for producing hot combustion gas. The heat exchanger (10) defines a multi-pass flow passage (11) for the combustion gas and includes a first plate member (30) and a second plate member (32). The first plate member (30) has a first series of parallel ridges (36) and valleys (38a-b), with at least one of the valleys (38a) being deeper than other of the valleys (38b). The second plate member (32) faces the first plate member (30) and includes a second series of ridges (36) and valleys (38a-b) that are parallel to the first series of ridges (36) and valleys (38a-b), with at least one of the valleys (38a) of the second series being deeper than other of the valleys (38b) of the second series. A first pass (14, 16) of the multi-pass flow passage (11) is defined by a number N1 of the ridges (36) and valleys (38a-b) of the first and second series. A second pass (16, 18) of the multi-pass flow passage (11) is defined by a number N2 of the ridges (36) and valleys (38a-b) of the first and second series. The at least one deeper valley (38a) of the first series cooperates with the at least one deeper valley (38a) of the second series to separate the second pass (16, 18) from the first pass (14, 16). <IMAGE>
Patent DE-69829062-T2 (DE)
Inventor: LISI GIUSEPPE
IPC: A61K9/107
Filed: 1998-10-06
Granted: 2006-02-09
Abstract: Use of flunarizine, a calcium channel blocking agent known for use as cerebral and peripheral vasodilator, in the treatment of glaucoma by topical administration. Differently from other calcium channel blockers already tested for use as antiglaucoma agents, flunarizine is highly active in lowering the intraocular pressure when administered by the topical ophthalmic route. The invention also comprises anti-glaucoma preparations containing flunarizine, or combinations of flunarizine with beta-blockers such as timolol.
Patent DE-69839176-T2 (DE)
Inventor: MOREAU JOHN
IPC: C04B40/00
Filed: 1998-05-14
Granted: 2009-03-26
Abstract: A cementitious mixture comprises a hydraulic cement; greater than about 10% by weight of a pozzolanic cement replacement selected from fly ash, slag, natural pozzolans, and mixtures thereof, based on the weight of said hydraulic cement and cement replacement; and a compatabilizing admixture, wherein the compatabilizing admixture comprises a compatabilizing polycarboxylate polymer dispersant capable of acting as a water reducer, in combination with an accelerator.
Patent DE-69902794-T2 (DE)
Inventor: CANHAM TREVOR
IPC: C12N15/09
Filed: 1999-07-22
Granted: 2003-08-07
Abstract: The present invention concerns a non-cell entering vehicle for transferring a material into a cell, the vehicle comprising bioactive and/or resorbable silicon, and a material to be transferred into a cell. The invention also concerns a vehicle for transferring a material into a cell, the vehicle comprising a sub-micron porous and/or polycrystalline silicon particle. <IMAGE>
Patent DE-69903960-T2 (DE)
Inventor: ELLIS FITCH
IPC: B32B27/12
Filed: 1999-09-08
Granted: 2003-07-17
Abstract: The present invention relates to waterproof fabric constructions, and more particularly to waterproof, breathable fabric constructions. The waterproof breathable fabric construction includes a microporous membrane layer and a nonporous layer. Cohesion is provided to the fabric construction through the use of both durable and breathable adhesives.
Patent DE-69911917-T2 (DE)
Inventor: ROSSI FABRICE
IPC: A47J27/04
Filed: 1999-11-19
Granted: 2004-08-19
Abstract: Heating part of a steamer, composed of a base structure (1), a heating body (2), a main water reservoir (4) communicating with the heating body (2) and enclosing an air volume, a lid (10) closing the reservoir (4), a filling orifice (8) opening on an exterior wall of at least one of the base (1) and the lid (10), a wall (5) closing at least one part of the air volume enclosed by the water reservoir (4) and disposed between the heating body (2) and of the filling orifice (8), the lid (10) having at least one opening (14) provided for the passage of steam toward a cooking receptacle disposed above the lid. The wall (5) descends into a reduced height zone (17) connected to the heating body (2') by a slope (23, 23') having a peak or a rib (24, 24') having a peak , the wall (5) descending into the reduced height zone (17) to a height lower than that of the peak of the slope (23, 23') or of the rib (24, 24'), the filling orifice (8) on the one hand and the slope (23, 23') or the rib (24, 24') on the other hand being disposed to one side and the other of the wall (5).
Patent DE-69913508-T2 (DE)
Inventor: VAN OOSTERHOUT VINCENTIUS
IPC: A61P37/00
Filed: 1999-03-19
Granted: 2004-09-23
Abstract: The present invention provides novel means and methods for treating unwanted side reactions in transplantations, such as GvH and allograft rejection. The invention provides immunotoxines comprising an antibody and a toxic substance, whereby cocktails of such conjugates directed to different targets associated with one population of cells, wherein one target is chosen from CD3 or CD7. The preferred combination is a cocktail directed against both.
Patent DE-69923180-T2 (DE)
IPC: C12Q1/686
Filed: 1999-09-28
Granted: 2006-01-12
Abstract: A purified thermostable enzyme is derived form the thermophilic archaebacterium Archaeoglobus fulgidus. The enzyme can be native or recombinant, is stable under PCR conditions and exhibits double strand specific exonuclease activity. It is a 3'-5'exonuclease and cleaves to produce 5'-mononucleotides. Thermostable exonucleases are useful in many recombinant DNA techniques, in combination with a thermostable DNA polymerase like Taq especially for nucleic acid amplification by the polymerase chain reaction (PCR). <IMAGE>
Patent DE-69923835-T2 (DE)
Inventor: SAUER R
IPC: A61P35/00
Filed: 1999-03-11
Granted: 2006-04-06
Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
Patent DE-69932822-T2 (DE)
Inventor: HAEGGMAN JAAKKO
IPC: B31B17/00
Filed: 1999-05-12
Granted: 2007-08-16
Abstract: The method for forming a container that comprises the following stages: the forming of the sidewall blank from a blank by wrapping it in a form that is closed in its horizontal section and by seaming its opposite edges together; the sealing of the sidewall blank at one end with a lid member, which is equipped with a discharge hole; the sealing of the sidewall blank at the other end with a bottom member; and the filling of the container. At first the lid member, the discharge hole of which is completely sealed with an openable closing member, is inserted into the end of the sidewall blank. Thereafter the container is filled through the end of the sidewall blank that was left open, and the container is sealed to form a tight container by sealing the end that was left open with the bottom member.
Patent DE-69936473-T2 (DE)
Inventor: FOLEY KEVIN
IPC: A61B17/28
Filed: 1999-10-27
Granted: 2008-03-06
Abstract: A spacer body, comprising a first portion and a second portion, said first portion moveably coupled to said second portion to form a spacer, said spacer having a reduced size configuration with a maximum height and a first maximum width and an expanded size configuration having said maximum height and a second maximum width, wherein said second width is greater than said first width; said spacer movable between said reduced size configuration and said expanded size configuration by movement of said first and second portions; a third portion joined to said first portion opposite said second portion, and a fourth portion extending between said second and third portions opposite said first portion; and wherein said second and third portions define end walls and said first and fourth portions define flexible side walls, said spacer moveable between said reduced size configuration and said expanded size configuration by movement of said flexible side walls.
Patent DE-69936605-T2 (DE)
Inventor: CATTANI ENNIO
IPC: B04C5/02
Filed: 1999-01-18
Granted: 2008-05-21
Abstract: A separator centrifuge (1) for separating solid particles suspended in a fluid comprises a container (2) having an inlet (A) for the fluid and an outlet (B) for the fluid once cleaned of the solid particles, the outlet (B) being situated higher than the inlet (A). The container (2) has a truncoconical wall (3) converging in a downwards direction, at a smaller end of which is located a discharge (4) which is connected to a chamber (7) for collecting the solid particles. The inlet (A) of the container comprises a plurality of mouths (13) each of which is crossed by a fraction of a total volume of fluid entering the container (2). The fluid is injected into the container (2) in a direction which has at least one component which is tangential with respect to an axis of the truncoconical wall (3). The separator is particularly useful for separating solid particles in discharge fluids coming from dental equipment. <IMAGE>
Patent DE-69938179-T2 (DE)
Inventor: BLANCHARD-BREGEON VERONIQUE
IPC: A61P25/16
Filed: 1999-04-22
Granted: 2009-02-12
Abstract: The invention concerns a combination of levodopa and riluzole or a pharmaceutically acceptable salt of said compound and the use of said combination for treating Parkinson Disease.
Patent HU-E033082-T2 (HU)
Title: Filter mat for contaminated air
Inventor: ANDERSSON ROLF
IPC: B01D46/52
Filed: 2005-06-14
Abstract: The invention relates to a filter mat, which is used in applications where it filters the flows of contaminated air that pass through it. In such mats, there are points where aerosols collect. This is disadvantageous as it lowers the efficiency of the mat. The present invention overcomes this by having, at these points, wicks (2) that absorb said collections.
Patent HU-E030139-T2 (HU)
Title: Compositions and methods for the treatment of infections
Inventor: AHMED RAFI
IPC: A61K39/00
Filed: 2007-12-26
Abstract: PD-1 antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced using these PD-1 antagonists in conjunction with an antigen from the infectious agent or tumor. Thus, subjects with infections, such as persistent infections can be treated using PD-1 antagonists. In additions, subjects with tumors can be treated using the PD-1 antagonists. In several examples, subjects can be treated by transplanting a therapeutically effective amount of activated T cells that recognize an antigen of interest and by administering a therapeutically effective amount of a PD-1 antagonist.
Patent HU-E027525-T2 (HU)
Title: Compositions of pd-1 antagonists and methods of use
Inventor: LANGERMANN SOLOMON
IPC: C12N15/62
Filed: 2009-08-25
Abstract: Methods of treating cancer and infectious diseases utilizing a treatment regimen comprising administering a compound that reduces inhibitory signal transduction in T cells, in combination with a potentiating agent, such a cyclophosphamide, to produce potent T cell mediated responses, are described. Compositions comprising the PD-1 antagonists and potentiating agents useful in the methods of the invention are also disclosed.
Patent HU-E028632-T2 (HU)
Title: Antisense oligonucleotides for inducing exon skipping and methods of use thereof
Inventor: WILTON STEPHEN DONALD
IPC: C07H21/00
Filed: 2005-06-28
Abstract: The invention relates to antisense oligonucleotides hybridizable to target regions in exons 53, 33, 45 or 50 of the Dystrophin gene, which oligonucleotides may comprise a non-natural backbone containing non-natural sugar moieties and/or non-natural inter-nucleotide linkages, and the use of such oligonucleotides in the treatment of muscular dystrophy, e.g. Duchenne Muscular Dystrophy.
Patent HU-E033886-T2 (HU)
Title: Recombinant avian paramyxovirus vaccine and method for making and using thereof
Inventor: BUBLOT MICHEL
IPC: C12N15/86
Filed: 2010-08-20
Abstract: The present invention encompasses engineered APMV compositions or vaccines. The vaccine or composition may be a recombinant APMV composition or vaccine. The present invention encompasses methods for modifying the genome of APMV to produce recombinant APMV; modified APMV prepared by such methods; DNA and protein sequences; and methods for infecting cells and host animals with such recombinant APMV.
Patent HU-E026737-T2 (HU)
Title: Serum amyloid p derivatives and their preparation and use
Inventor: WILLETT W SCOTT
IPC: A61K38/17
Filed: 2010-06-04
Abstract: One aspect of the present invention relates to the surprising discovery that modification of a glycan structure on a human SAP polypeptide can increase the biological activity of the SAP polypeptide relative to a corresponding sample of wild-type SAP isolated from human serum. The disclosure provides both variant human SAP polypeptides and methods for making the same. In particular, the present invention provides methods and compositions for in vitro and in vivo addition, deletion, or modification of sugar residues to produce SAP polypeptides, such as a human SAP polypeptide, having a desired glycosylation pattern.
Patent HU-E036180-T2 (HU)
Title: Vaccine composition containing synthetic adjuvant
Inventor: REED STEVEN G
IPC: A61K39/39
Filed: 2007-09-26
Abstract: Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glucopyranosyl lipid adjuvant (GLA) that is provided in substantially homogenous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier.
Patent TR-200002836-T2 (TR)
Title: Kuyu kapağının yerleştirilmesi için tertibat
Inventor: HAGEN PETER
IPC: E02D29/14
Filed: 1999-04-08
Abstract: Bulus, bir kapagin yerlestirilmesi için olusturulmus bir üst çerçeve parçasina (1) ve bu çerçeve parçasinin (1) çevresindeki yol kaplamasina (10,11) ankrajlanmasi için tutma elemanlarinin yerlestirildigi ve ayrica üst çerçeve parçasina (1) göreceli olarak hareket eden bir baglanti parçasina (40) sahip olan ve kuyu (delik, mazgal, rögar) kapaklarinin ve benzerlerinin yerlestirilmesi için bir tertibat ile ilgilidir. Baglanti parçasi (40) ile çerçeve parçasi (1) arasinda bir ankraj parçasinin (20) ve gerektigi takdirde bir yada daha fazla dengeleme halkasinin (30) öngörülmesi ile ve bunlarin elastik olarak sekillendirilebilen malzemeden olusmasi ve ankraj parçasi (20) ve dengeleme halkasinin (30) herbirinin bir halka biçiminde yive (22,32) sahip olarak baglanti parçasinin (40) içine girebilir sekilde olmasi ile basit bir yapi tarzi elde edilir ve bu sekilde kaymalara izin veren bir baglanti temin edilir.
Patent TR-200100377-T2 (TR)
Title: Aß Protein üretimi inhibitörleri olarak sukinoilamino laktamlar.
Inventor: OLSON RICHARD E
IPC: A61K31/5513
Filed: 1999-08-07
Abstract: Bu bulus, ilaç ve biyo-etkileyici özellikler tasiyan Formül (I)'e ait yeni laktamlar veya farmasötik açidan kabul gören tuzlar veya bunlarin ön ilaci, bunlarin farmasötik kompozisyonlari ve kullanim metotlari ile ilgilidir. Bu yeni bilesikler, amiloid öncü proteininin islemesini önler ve daha özel olarak da Abeta-peptit üretimini önler ve böylece amiloid proteininin nörolojik tortularinin olusmasini engelleyecek sekilde hareket eder. Daha özel olarak mevcut bulus, Alzheimer hastaligi ve Down sendromu gibi beta-amiloid üretimi ile ilgili nörolojik bozukluklarin tedavisi ile ilgilidir.
Patent TR-200102875-T2 (TR)
Title: Neurokinin-1 reseptörü antagonistler olarak n-(2-fenil-4-amino-butil)-1-naftamidler.
Inventor: BERNSTEIN PETER ROBERT
IPC: A61P37/08
Filed: 2000-04-03
Abstract: R1R2N-CH2CH2-CHAr1-CH2-NR3-CO-R4 genel formül (I)'e sahip bir bilesikte R1 hidrojen, C1-6alkil, C2-6alkenil, aril, C1-6alkonoil, C1-6 alkoksikarbonil ya da arilkarbonil 'dir; benzer gruplardan herhangi birine vekalet edilebilir; R2 hidrojen ya da C1-6alkil'dir; ya da R1 ve R2 istege bagli olarak vekalet edilen bir morfolino halkasi olusturmak üzere birlestirilmistir; Ar1 halo tarafindan vekalet edilen fenil mono- ya da di-'dir; R3 hidrojen ya da C1-6alkil'dir; R4 istege bagli olarak naft-1-il; ya da onun eczacilikla ilgili kabul edilebilir tuzlari tarafindan vekalet edilendir. Bu bilesikler, iç sebeplerden dogan neuropeptid tasikininlerinin özellikle neurokinin 1 (NK1) reseptörünün farmakolojik hareketlerine düsmanlik ederler.
Patent TR-200103266-T2 (TR)
Inventor: HAGEN MICHAEL
IPC: A61K39/155
Filed: 2000-05-12
Abstract: The use of 3-O-deacylated monophosphoryl lipid A or monophosphoryl lipid A and derivatives and analogs thereof, in combination with a cytokine or lymphokine such as granulocyte macrophage colony stimulating factor or interleukin-12 is useful as an adjuvant combination in an antigenic composition to enhance the immune response in a vertebrate host to a selected antigen.
Patent DE-602004001164-T2 (DE)
Inventor: IKUTA TAKESHI
IPC: A01K89/0155
Filed: 2004-05-12
Granted: 2007-04-26
Abstract: A spool control unit includes a circuit board (70), a plurality of electric components, an external device connector (91), and an insulating film (90). The circuit board (70) includes a printed circuit (72) on a surface thereof. The plurality of electric components include a microcomputer (59) that controls the fishing equipment through a control program, and are disposed on the circuit board (70) such that they are electrically connected to the printed circuit (72). The external device connector (91) is mounted on the circuit board (70) such that it is electronically connected to the printed circuit (72), and serves to connect to an external device (100). The insulating film (90) covers at least a portion of the circuit board (70) as well as the electric components but does not cover the regions of the circuit board (70) on which the external device connector (91) is mounted. <IMAGE>
Patent DE-602004004596-T2 (DE)
Inventor: STROPPIANA FERNANDO
IPC: B32B27/32
Filed: 2004-11-18
Granted: 2007-11-15
Abstract: A stratified-structure laminar covering material, which can be used for example as a flooring for sports facilities, comprises an outermost layer (101), a bottom layer (103), and an intermediate layer (102) set between the outermost layer (101) and the bottom layer (103). The aforesaid layers (101, 102 and 103) comprise a matrix constituted by a mixture of polyolefin and thermoplastic elastomer (TPE), the matrix being substantially identical for all three layers. The matrix of the outermost layer (101) is substantially free from fillers and has a first value of density. The bottom layer (103) contains fillers so as to have a second value of density greater than said first value of density, and the intermediate layer (102) contains fillers so as to have a third value of density intermediate between the first value of density of the outermost layer (101) and the second value of density of the bottom layer (103).
Patent DE-602004005043-T2 (DE)
Inventor: WIKSELL HANS
IPC: A61B10/00
Filed: 2004-09-27
Granted: 2007-11-22
Abstract: The present invention relates to an arrangement for taking a sample of cells from a suspicious lesion or a tumour with the so called fine needle aspiration technique, which arrangement provides a good penetration of tumours, especially small and/or hard fibrous tumours, and in the meantime yielding an increased amount of cells in the sample, by applying a longitudinal movement to the needle when the needle is penetrating the tumour and by applying a rotational movement to the needle when the needle is positioned inside the tumour. The arrangement is further provided with heat generating means in order to apply a short pulse of heat to the needle in order to lower the risk for the tumour to spread.