baber/WOPTO huggingface dataset:
Patent CZ-292453-B6 (CZ)
Title: Isolated nucleic acid molecule encoding a human TIE-2 ligand and use thereof
Inventor: DAVIS SAMUEL
IPC: C12N5/06
Filed: 1995-10-06
Abstract: The present invention provides for an isolated nucleic acid molecule encoding a human TIE-2 ligand. In addition, the invention provides for a receptor body and an antibody, which both specifically bind that human TIE-2 ligand. The invention further provides for an antagonist of human TIE-2 ligand. The invention also provides for therapeutic compositions as well as a method of blocking blood vessel growth, a method of promoting neovascularization, a method of promoting the growth or differentiation of a cell expressing the TIE-2 receptor, a method of blocking the growth or differentiation of a cell expressing the TIE-2 receptor and a method of attenuating or preventing tumor growth in a human.
Patent CZ-295230-B6 (CZ)
Title: Hydraulic filling mixture
Inventor: ADAMEC ZDENEK ING
IPC: E21F15/00
Filed: 1999-04-06
Abstract: The present invention relates to a hydraulic filling mixture intended particularly for securing and liquidation of mine excavations, optionally maintenance and reclaiming of grounds for building construction. The invented hydraulic filling mixture comprises 50 to 80 parts by weight of waste product of coal or coke combustion in the form of light ash and/or dump ash, 50 to 20 parts by weight of gas purification sludges and water in an amount of 50 to 100 percent of the total weight of the both preceding components of the mixture.
Patent CZ-284083-B6 (CZ)
Inventor: WORNER CHRISTOPH
IPC: D04B15/50
Filed: 1996-04-25
Abstract: Zařízení pro přívod nití, zejména elastomerových nití, u pletacích strojů obsahuje dvoudílnou skříň (3), v níž jsou otočně uloženy hnací a úložné válce (13, 14, 13', 14'), uspořádané rovnoběžně ve vzájemném odstupu. Skříň (3) ohraničuje vnitřní prostor (23), v němž jsou umístěny převodové prostředky (25) pro pohon alespoň jednoho z úložných válců (13, 13', 14, 14'). Převodové prostředky (25) přenášejí sílu z hnacího kola upevněného na hřídeli vyčnívajícím ze skříně (3) na alespoň jeden úložný válec (13, 13', 14, 14'). Úložné válce (13, 13', 14, 14) jsou uloženy prostřednictvím kuličkových ložisek (41, 42, 43, 44) ve vybráních (36a až 36f) provedených ve skříni (3). Tato vybrání (36a až 36f) jsou vytvořena v dílech (10, 11) skříně (3), které jsou vyrobeny vstřikovým litím jako jeden kus. Dělicí spára (8), u které díly (10, 11) navzájem sousedí, probíhá všemi vybráními (36), takže kuličková ložiska (41, 42, 43, 44) jsou mezi díly (10, 11) upevněna. Upevněním dílů (10, 11) k sobě jsou souŕ
Patent CZ-299721-B6 (CZ)
Title: Medicament for treating urinary incontinence
Inventor: MEESE CLAUS
IPC: A61P13/00
Filed: 1999-05-11
Abstract: In the present invention, there is disclosed the use of (.+-.)-2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethylphenylisobutyrate ester, R-(+)-2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethylphenylisobutyrate ester or salt thereof with physiologically acceptable acids for the preparation of a medicament intended for the treatment of urinary incontinence.
Patent CZ-285399-B6 (CZ)
Title: Apparatus for coiling coils in a furnace from hot-rolled metal strips
Inventor: POKORNY ARNOST PROF ING CSC
IPC: C21D9/68
Filed: 1995-09-12
Abstract: The apparatus is formed inside the furnace from hot-rolled metal strips (57) in the coiling box (51) by modified forming rollers (11, 12, 13, 14), which are coupled with the drive and inserted by means of rotary bearing steel constructions (44) rotating on their own rotary axes and swivelling on a corresponding swivelling axle (O1, O2, O3, O4), whereas the swivelling axes (O1, O2, O3, O4) are different from the rotary axes of the supporting forming rollers (11, 12, 13, 14), but identical with axes of rotation of the bearing steel constructions (44). According to the invention each bearing steel structure (44) is completed and formed with the help of insulation materials so that its cross-section, vertical to its axis, is formed by a shaped part (46) in the shape of a recess and a circular form (45), whereas surface of the shaped part (46) is in a reverse to the centre of the roll (6) and at a distance from the centre of the roll (6), which is greater than 1/2 the final diameter (D) of the roll (6).<IMAGE>
Patent CZ-286162-B6 (CZ)
Title: Process for preparing enantiomer piperazine derivative
Inventor: BUIZER NICOLAAS
IPC: C07D327/06
Filed: 1997-09-15
Abstract: In the present invention there is disclosed a process for preparing a substantially pure enantiomer piperazine derivative of the general formula IX, in which X represents oxygen, sulfur, the group NH, N-alkyl containing 1 to 4 carbon atoms or CHi2, Yi1, Yi2 and Yi3 each represents hydrogen, a halogen alkyl containing 1 to 4 carbon atoms , alkoxyl containing 1 to 4 carbon atoms, haloalkyl containing 1 to 4 carbon atoms a nitro group or a cyano group, A represents alkylene containing 2 to 4 carbon atoms, B represents an optionally substituted phenyl or     heterocyclic group and C*-atom is in R-configuration. The invented process is characterized in that (a) a racemic alcohol of the general formula I is acylated with an acylating agent in the presence of  an enzyme exhibiting stereoselective esterification activity, the non-esterified compound is separated from the formed ester that is subsequently subjected to hydrolysis and a waste undesired alcohol enantiomer is then converted under basic conditions to the starting racemic alcohol that is brought again back into reaction, (b) a free hydroxy group of so obtained alcohol enantiomer is protected, (c) a nitro group of the product is reduced to an amino group, (d) the amino compound is then converted to a piperazine compound, (e) said piperazine compound is subsequently subjected to derivatization and (f) from the obtained compound the protecting group is cleaved.
Patent CZ-293494-B6 (CZ)
Title: Pharmaceutical composition containing selected lanthanum carbonate hydrates
Inventor: MURRER BARRY ANTHONY MURRER BA
IPC: C01F17/00
Filed: 1996-03-19
Abstract: The invented selected lanthanum carbonate hydrates are used for the preparation of a pharmaceutical composition intended for administering into the gastrointestinal tract, to treat hyperphosphataemia in patients with renal failure.
Patent CZ-300530-B6 (CZ)
Title: Method for heating or cooling solid material filling and device for making the same
Inventor: CONOCHIE DAVID STEWART
IPC: F28D9/00
Filed: 1998-03-05
Abstract: The present invention relates to a method for heating or cooling a solid material filling comprising the steps of: feeding the material filling for forming a solid material filling bedding in a processing container (50) having one or more channels for heat-exchange fluid flow, said heat-exchange fluid flow through one or more channels; and supplying a processing fluid to the container (50). The processing fluid circulates through the filling bedding, whereas the circulation step includes withdrawal of at least a portion of the processing fluid from one or more sections of the processing container (50) and after that re-supplying the processing fluid to other container (50) sections, whereas between the heat-exchange fluid and the filling and between the heat-exchange fluid and the processing fluid an indirect heat exchange occurs, whereas between the processing fluid and the filling a direct heat exchange occurs during the processing fluid circulation through the bedding. there is also disclosed a device for making the above-described method, said device comprising means for supplying a processing fluid to the container (50) and means for ensuring circulation of the processing fluid in the bedding.
Patent CZ-291024-B6 (CZ)
Title: Isolation process of hepatitis B viral surface antigen comprising the preS2 peptide and vaccine containing such antigen
Inventor: PARK SOON-JAE
IPC: C07K1/36
Filed: 1995-12-08
Abstract: In the present invention there is disclosed a process for isolating hepatitis B viral surface antigen comprising the preS2 peptide from the cells of a recombinant organism, which isolation process is characterized in that said cells are disrupted using a buffer containing a chaotropic salt.
Patent CZ-298701-B6 (CZ)
Title: Medicament for healing bones and repair of fractures
Inventor: VICKERY BRIAN HENRY
IPC: C07K14/635
Filed: 1998-09-02
Abstract: The present invention relates to the use of a polypeptide analog of parathyroid hormone related peptide (PTHrP) and salts thereof, wherein amino acid residues 22-31 of said PTHrP analog form an amphipathic {alpha}-helix, Glu Leu Leu Glu Xaa Leu Leu Glu Lys Leu, wherein Xaa represents an amino acid residue with a positive charge, for the preparation of a medicament intended for healing bones and repair of fractures.
Patent CZ-296075-B6 (CZ)
Title: Process for preparing 3-(2-aryl/alkyloxy-5-methylphenyl)-3-phenylpropanol
Inventor: LUSTIG PETR
IPC: C07C41/18
Filed: 2004-02-05
Abstract: In the present invention, there is disclosed a Process for preparing 3-(2-aryl/alkyloxy-5-methylphenyl)-3-phenylpropanol of the general formula I, in which R represents a protecting group in the form of an aliphatic or arylalkyl radical, wherein the preparation process comprises reacting a 3-(2-aryl/alkyloxy-5-methylphenyl)-3-phenylpropanoic acid of the general formula II, in which R is as specified above and being dissolved in toluene, with a toluene solution of sodium dihydrido bis(2-methoxyethoxy)-aluminate at a temperature ranging from 0 to 60 degC. After finish of the reaction the mixture is mixed, after optional cooling down to a temperature in the range of 0 to 20 degC, with an aqueous solution of inorganic hydroxide, subsequently with water, and finally the organic layer is separated, dried and thickened.
Patent CZ-303939-B6 (CZ)
Title: Proton-conducting inorganic-organic phosphorus-silicone membrane intended for medium thermal H2/O2 fuel cells
Inventor: MIKA MARTIN
IPC: H01M8/10
Filed: 2012-03-21
Abstract: In the present invention, there is disclosed a membrane exhibiting the weight ratio of P to Si in the range of 1.0 to 5, preferably 2.2 to 3. The membrane exhibits a proton conductivity expressed as a specific ionic conductivity up to 4.0 Sme-1 at temperatures in the range of 25 to 150 degC and at relative humidity RH2~0 percent. The membrane contains a reinforcing material being selected from the group of reinforcements consisting of inorganic fibers, glass fibers, mineral fibers, ceramic fibers, carbon fibers, in the form of fibers or fabrics. The membrane can be prepared by proportioning of the starting components being represented by: Hi3POi4 as a base component and a group donor for ensuring proton conductivity of the proton-conducting inorganic-organic phosphorus-silicone membrane; SiOi2 in the form of hydrophilic nanoparticles with specific surface area in the range of 100 to 500 me2ge-1, and preferably 200 +/- 10 me2ge-1; (CHi3)i2SiCli2 as a polymeric precursor for formation of linear polydimethyl siloxane chains in the proton conducting inorganic-organic phosphorus-silicone membrane; and Si(OCi2Hi5)i4 as a polymeric precursor that is a vulcanizing precursor for the formation of 3D microstructure from the linear polydimethyl siloxane chains in the proton conducting inorganic-organic phosphorus-silicone membrane.
Patent CZ-307806-B6 (CZ)
Title: A method for treating waste water with controlled de-nitrification and equipment for carrying out the process
Inventor: TOPOL JAN
IPC: C02F101/16
Filed: 2012-04-02
Abstract: The invention concerns a process for treating waste water with controlled de-nitrification and a method for carrying out the process in a domestic sewage treatment plant. Waste water is fed to the water treatment plant’s levelling tank and pumped from there to the activation tank where it is nitrified by mixing with activated sludge and aeration. After the necessary technological time for nitrification expires and the waste water level in the buffer tank is below the specified working level, the re-pumping ends and pumping waste water from the activation tank to the levelling tank starts and mixed during the re-pumping. This de-nitrification phase ends when the working level in the levelling tank is reached, when the re-pumping of the denitrified and waste water mixture from the buffer tank to the activation tank is initiated, where further nitrification takes place. The sewage treatment plant consists of a levelling tank with a waste water inlet, a water level measuring device, an aeration system and a pump for re-pumping water from the levelling tank to the activation tank, and an activation tank with a water level measuring device and an aeration system. The activation tank has a device for draining the purified water consisting of a purified water reservoir with a filling pump and outflow for purified water from the waste water treatment plant and from the sampling equipment. The sampling equipment consists of a water pump tank, a clean water pump and a movable arm with a plunger inlet and a float elbow. The clean water pump discharge pipe ends in the clean water tank and the discharge pipe of the of the discharge line ends in the clean water pump tank.
Patent SK-286618-B6 (SK)
Title: Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl] thiazolidine-2,4-dione, maleic acid salt, method for the production thereof, pharmaceutical composition containing thereof and its use
Inventor: BLACKLER PAUL DAVID JAMES
IPC: A61K31/00
Filed: 1998-12-14
Abstract: Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy] benzyl]thiazolidine-2,4-dione, maleic acid salt, which comprises water in the range of from 0.4 to 2.5 % by weight and also has one of the features defined in claims. Described is also a method for the production of such compound, a pharmaceutical composition containing such compound and use of such compound in a medicine.
Patent CZ-297714-B6 (CZ)
Title: Method for processing work pieces by removing material
Inventor: ENGELI MAX
IPC: G05B19/4103
Filed: 1998-12-08
Abstract: The invention relates to a method for processing a work piece by removing material with a tool in which the tool is guided over the work piece in paths (B). The pivoting and cambering angle of the tool is selected in every point such that the width of a tolerance zone is optimized. Within said zone, the effective zone (K) of the tool is located in a tolerance zone of the desired specified surface (Psi) of the work piece. The distance between two points (Pil, Pir) is maximized, said points characterizing the furthest outlying points of the tolerance zone. As a result, it is possible to produce surfaces having a high precision with a small number of paths.
Patent CZ-300730-B6 (CZ)
Title: Container for dispensing fluid, comprising a pressure control device with activation step
Inventor: VLOOSWIJK JOHANNES JACOBUS THOMAS
IPC: B67D1/12
Filed: 1999-12-14
Abstract: In the present invention, there is disclosed a container (1, 101) adapted for dispensing fluid with a device (8, 108) for control of substantially constant, preset pressure in the container (1, 101) with a first chamber (24, 124) for pressure fluid , a second chamber (60, 160) for a control pressure and a third chamber (62, 162) connected with an interior (4) of the container (1, 101). Between the first chamber (24, 124) and the second chamber (60, 160), there is provided a passage opening with a closing element for closing the passage opening during usage. Control means are arranged for at least partial movement of the closing element via movable or deformable wall section of the second chamber (60, 160) at a lower pressure in the third chamber (62, 162) if compared with the control pressure, for passage of the pressure fluid from the first chamber (24, 124) to the third chamber (62, 162). The control means are functionally disconnected to a closing element before use, whereas the pressure control device (8, 108) is provided for functional connection of the control means with the closing element during activation before use. At this way of the container fabrication is the support of the can shape provided with a first part of the pressure control device (8, 108) including at least the closing element set with bias in closed position and opened by outer excessive pressure. The device (8, 108) is supplied with a fluid at relatively high pressure and after suppression of the excessive pressure, the closing element is brought into the closed position. Then the second part of the pressure control device (8, 108) comprising pressure control means and pushing the closing element against bias to its open position is placed onto the first part thereof when the ambient pressure is lower than the control pressure. are to the first part of the device (8, 108) placed its second part comprising pressure control means, pressing the closing element against bias to its opened position while the ambient pressure is lower than the control pressure. With the first and second part connected, the device (8, 108) is introduced into the container (1, 101) filled with fluid intended to be dispensed and the passage opening gradually closes, while the control means functionally connect with the closing element via an activation step.
Patent CZ-299232-B6 (CZ)
Title: Isolated antibody specifically binding to RG1 polypeptide fragment and immunoconjugate comprising such antibody
Inventor: HARKINS RICHARD
IPC: C12Q1/00
Filed: 2000-12-15
Abstract: The present invention generally relates to novel human extracellular matrix polypeptides, designated RG1, polynucleotides encoding the polypeptides, methods for producing the polypeptides, expression vectors and genetically modified host cells for expression of the polypeptides. The invention further relates to methods for utilizing the polynucleotides and polypeptides in research, diagnosis, and therapeutic applications. In concrete terms, the present invention relates to isolated antibody, or antibody fragment, which specifically binds to a polypeptide fragment having an amino acid sequence being entirely identical as a fragment but not the complete amino acid sequence of the RG1 polypeptides. Another object of the present invention is an immunoconjugate comprising the above-indicated isolated antibody, or antibody fragment, which are conjugated to a therapeutic agent.
Patent SK-285820-B6 (SK)
Title: Polymorphic forms of crystalline azobicyclo(2,2,2)octan-3-amine citrate and pharmaceutical compositions containing them
Inventor: CASTALDI MICHAEL JAMES
IPC: A61K31/00
Filed: 2000-05-18
Abstract: Crystalline form (2S, 3S)-N-(methoxy-5-t-butylphenylmethyl- 2-diphenylmethyl-1-azobicyclo (2,2,2) octan-3-amine citrate(citrate monohydrate) is a stable polymorphic form A, exhibiting in the X-ray diffraction analysis the following distances d (nm) at characteristic peaks 1 to 7: 1.328; 0.770; 0.634; 0.533; 0.506 and 0.440. It is described a method for preparation of this form, a pharmaceutical composition, having CNS active NK-1 receptor antagonist activity, containig this form in an amount effective for the treatment of emesis and a pharmaceutically effective carrier. Further, it is described use of this form in pharmaceutical and therapeutic applications.
Patent EP-1642860-B8 (EP)
Inventor: SO KWOK KUEN
IPC: B67B7/70
Filed: 2004-11-11
Granted: 2009-03-11
Abstract: A can opener (100) has two pivotal handles (110 and 120), a traction wheel (200) and a cutter blade (300) movable by respective handles (110 and 120) for cutting open a can, and a pivotable lever (400). There is a ratchet assembly (500) driven by the lever (400) upon reciprocation for operating the traction wheel (200) and cutter blade (300), which has a ratchet wheel (510) connected with the traction wheel (200) and a spring-loaded pawl (520) movable by the lever (400) for turning the ratchet wheel (510) in a driving direction (D) upon reciprocation of the lever (400). The pawl (520) has front and rear ends (521 and 522) taken in the driving direction (D), with the front end (521) in engagement with the lever (400) and the rear end (522) engageable with the ratchet wheel (510) for turning the same.
Patent EP-1768258-B8 (EP)
Inventor: JUNGBAUER MARKUS
IPC: F24C7/08
Filed: 2006-09-23
Granted: 2010-05-19
Abstract: The arrangement has a microcontroller that is arranged in such a manner that it forms an oscillating circuit in a capacitor (C1) and a sensor in an operation mode for detecting a cooking vessel and another oscillating circuit in an inductor (L1) and the sensor in another operation mode for detecting a contact of the vessel. Switching units (S1, S2) are controllable by the microcontroller, where the switching unit (S1) is provided between a connection of the sensor and the inductor, and the switching unit (S2) is provided between the connection of the sensor and the capacitor.
Patent EP-2000324-B8 (EP)
Title: Envelope filling machine
Inventor: PONTI FRANCESCO
IPC: B43M3/04
Filed: 2007-06-05
Granted: 2011-02-16
Abstract: An envelope filling machine for introducing sheets (2) into envelopes (3) includes a sliding surface (5), for transferring the sheets to an envelope filling station (1) by means of pushing lugs (7), operated along the sliding surface (5). An envelope supplying conveyor (16) supplies individual envelopes (3) to the station (1) placing them between vertical shafts (23) of a pair of screws (21). The turns of the screws (21) hold the sides of the envelopes and move each envelope (3) downwards keeping the envelope (3) separated from a. subsequent envelope (3). When the envelope (3) has come to rest on a conveyor belt (25) placed between and under the screws (21), the lugs (7) push the sheets (2) into the envelope (3), which is kept steady by movable stop strips (17) yeldingly maintained by elastic means.  When the sheets (2) are fully inserted, the lugs push the envelope (3) to force the movable strips (17) to swing and let the filled envelope (33) leave the envelope filling station (1).
Patent BR-PI0402077-B8 (BR)
Title: nanocápsulas contendo princípios ativos lipofílicos, uso de nanocápsulas, composições farmacêuticas e processo de preparação de nanocápsulas
Inventor: LUCIANA MENEGATTI
IPC: A61K9/51
Filed: 2004-05-19
Abstract: nanocápsulas contendo princípios ativos lipofílicos, uso de nano-cápsulas, composições farmacêuticas e processo de preparação de nanocápsulas a presente invenção refere-se a nanocápsulas contendo macrolídeos, processo para produzi-ias, composições farmacêuticas e medicamentos que as contêm, e uso de com-posições e medicamentos que as contêm.
Patent BR-PI0507521-B8 (BR)
Title: processo para preparação de microesferas biodegradáveis monodispersas
Inventor: AUDREY ROYERE
IPC: B01J13/12
Filed: 2005-03-03
Abstract: processo para preparação e uso das microesferas biodegradáveis monodispersas e microesferas biodegradáveis monodispersas a presente invenção refere-se a um processo para a preparação de microesferas biodegradáveis monodispersas que compreendem as etapas de: (a) preparação de uma emulsão que compreende pelo menos uma fase polimérica e pelo menos uma fase aquosa, sendo que a razão das viscosidades entre a fase polimérica dispersa e a fase aquosa contínua está compreendida entre 0,1 e 10; (b) submissão da emulsão obtida a um cisalhamento laminar controlado; (c) eliminação do solvente da fase polimérica; e (d) isolamento das microesferas assim obtidas. a presente invenção refere-se também ao uso das microesferas assim preparadas.