baber/WOPTO huggingface dataset:
Patent IL-103603-A (IL)
Title: Proteins involved in the biosynthesis of a polypeptide antibiotic method for producing said protein and dna encoding them
IPC: C12N15/62
Filed: 1992-10-30
Abstract: Novel recombinant DNA molecule (I) has a sequence corresp. to one or more DNA sequences contd. in a Bgl II fragment of the 54 Rpb episomal element pTii32 from staphylococcus epidermis and codes for at least one protein having EpiB, EpiC, EpiD, EpiP or EpiQ enzymatic activity; or (I) is capable of hybridising to the BglII fragment and codes for at least one protein with the above enzymatic activities. Also claimed are: the protein EpiB, EpiC, EpiD, EpiP or EpiQ in the absence of impurities with which it is normally associated; a fusion protein compising one of EpiB, C, D, P or Q and an auxiliary protein, a fusion protein in which one of the Epi B, C, D, P or Q is fused to an auxiliary protein such that the junction between the Epi protein and the auxiliary protein can be cleaved by an enzyme; and a method of producing a protein with at least one of the structural features of a lantibiotic. In the novel method comprising inserting a DNA sequence coding for a predetermined aminoacid sequence in a vector plasmid such that it is under the control of a regulator promoter, transforming the resulting plasmid vector into a host and cultivating the host so as to express the DNA and isolating the protein, the improvement comprises also transforming the host by a DNA sequence or sequences comprising functionally operable genes coding for EpiB, C, D, P or Q (or an active variant), the genes being expressed during cultivation of the host so that the resulting protein has at least one of the structural features of a lantibiotic.
Patent IL-121237-A (IL)
Title: Process and intermediates for preparing 2, 3-disubstituted 4-hydroxyanilines
IPC: C07C245/08
Filed: 1997-07-04
Abstract: Process for preparing compounds of the formula in which X and Y independently of one another each represent halogen or CN by reacting (a) phenols of the formula in which X and Y are as defined above with diazonium salts of the formula 806 ט' באייר התשס" ב - April 21, 2002 in which n represents a number 0 to 5, Z represents halogen, alkyl, NO2, COOH, CN and SO3H, Z in the case of n O2 optionally having different meanings, A represents a counterion and (b) subsequent reduction of the diazene of the formula obtainable by process step (a) to give the target compound.
Patent IL-124789-A (IL)
Title: Covalent lipid-phosphonocarboxylic acid conjugates and application thereof as antiviral medicaments
IPC: A61K47/54
Filed: 1996-12-16
Abstract: Phospholipid compounds of the formula in which R1 is a -(CH2)e- cycl-group in which e is an integer between 4 and 16; the moiety -(CH2)e- is straight-chain or branched, saturated or unsaturated alkylene chain, in which one of the carbon atoms from position 3 onwards can be replaced by a heteroatom (oxygen, nitrogen or sulfur); cycl represents a cyclic alkyl residue with 5 to 7 carbon atoms or phenyl in which one carbon atom in the saturated or aromatic ring can be replaced by nitrogen and the saturated or aromatic rings can be substituted once or several times by C1-C10 alkyl, C1-C10 alkoxy, C1-C10 alkylmercapto or halogen; R2 can be hydrogen, a straight chained or branched saturated or unsaturated alkyl chain with 1 to 20 carbon atoms, or R2 can have the same meaning as R1, provided that R1 can also be hydrogen or a straight- chain or branched, saturated or unsaturated alkyl chain with 1 to 20 carbon atoms, if at the same time R2 is a (CH2)e-cycl- group in which e has the same meaning as above; R3 is hydrogen, a straight-chained or branched alkyl chain with 1-6 carbon atoms; neopentyl, thexyl or phenyl, choline, ethanolamine, carnitine, C5-C7-cycloalkyl residue, benzyl or one of the following groups 420 כ" ו באדר התשס" ב - March 10, 2002 wherein R4 represents C1-C6-alkyl, benzyl or phenyl and R5 and R6 are C1-C6-alkyl and n is 1,2 or 3; X denotes a valency dash, oxygen, sulfur, oxycarbonyl, carbonyloxy, carbonylamido, aminocarbonyl, a sulfinyl or a sulfonyl group, Y denotes a valency dash, oxygen, sulfur, oxycarbonyl, carbonyloxy, carbonylamido, amidocarbonyl, a sulfinyl or sulfonyl group, m represents 0, 1, 2, or 3, tautomers, optical isomers and racemates thereof and their physiologically tolerated salts of inorganic and organic bases and prodrugs of compounds of formula (I).
Patent IL-125348-A (IL)
Title: Calcination using liquid metal heat exchange fluid
IPC: B01J6/00
Filed: 1997-01-17
Abstract: An apparatus (10) for calcining a material, the apparatus comprising a calcination vessel which houses a heat exchanger (12) arranged to transfer heat to the material from a liquid metal heat exchange fluid (14) arranged to flow through the heat exchanger. 105 כ" ז בסיון התשס" א - May 20, 2001
Patent IL-131030-A (IL)
Title: Isolated monoclonal antibodies or antigen binding fragments thereof that bind to a human trail-r polypeptide
IPC: C12N15/12
Filed: 1999-07-21
Abstract: A protein designated TRAIL receptor binds the protein known as TNF-Related Apoptosis-Inducing Ligand (TRAIL). The TRAIL receptor finds use in purifying TRAIL or inhibiting activities thereof. Isolated DNA sequences encoding TRAIL-R polypeptides are provided, along with expression vectors containing the DNA sequences, and host cells transformed with such recombinant expression vectors. Antibodies that are immunoreactive with TRAIL-R are also provided.
Patent IL-139150-A (IL)
Title: Desensitizing dentifrice containing potassium and tin salts
IPC: A61K8/00
Filed: 1999-04-22
Abstract: A composition for treating dentinal hypersensitivity by applying to teeth requiring relief from hypersensitivity an improved desensitizing two component dental composition which eliminates or reduces the discomfort and pain associated 1483 א' בתמוז התשס" ד - June 20, 2004 with dentinal hypersensitivity which composition comprises a first aqueous dentifrice component containing a potassium salt desensitizing agent and about 0.5 to about 15% by weight of an alkali metal compound to maintain the pH of the component in the range of about 8 to about 11, a second aqueous dentifrice component containing a desensitizing stannous salt and in which the alkali metal compound is absent, the first and second components being maintained separate from each other until dispensed for application to teeth requiring relief from dentine hypersensitivity, whereby heightened desensitization is observed.
Patent IL-149885-A (IL)
Title: Non-human multicellular organism and methods for controlling the same
IPC: C12N15/63
Filed: 2002-05-28
Abstract: The invention relates to a non-human multicellular organism carrying a dominant lethal genetic system, the lethal effect of which is conditional, wherein the lethal effect of the lethal system occurs in the natural environment of the organism.
Patent IL-150696-A (IL)
Title: Pharmaceutical compositions containing benzimidazole derivatives and processes for the manufacture thereof
IPC: A61K33/00
Filed: 2002-07-11
Abstract: The invention provides a solid oral pharmaceutical composition in capsule or powder dosage form comprising: 
a) omeprazole or a single enantiomer thereof, including a salt or other derivative thereof; and 
b) sodium bicarbonate;  
wherein the dosage form is not enteric coated or time-released, and the composition comprises from 7 to 25 mEq sodium bicarbonate per 20 mg omeprazole.
Patent IL-152267-A (IL)
Title: Method for reducing noise and cavitation in machines and pressure exchanges which pressurize or depressurize fluids by means of the displacement principle
IPC: F15B21/047
Filed: 2001-04-11
Abstract: A pressure exchanger for simultaneously reducing the pressure of a high pressure liquid and pressurizing a low pressure liquid. The pressure exchanger has a housing having a body portion; with end elements at opposite ends of the body portion. A rotor is in the body portion of the housing and in substantially sealing contact with the end plates. The rotor has at least one channel extending substantially longitudinally from one end of the rotor to the opposite end of the rotor with an opening at each end. The channels of the rotor are positioned in the rotor for alternate hydraulic communication with 1) high pressure liquid and 2) low pressure liquid, in order to transfer pressure between the high pressure liquid and the low pressure liquid. Because of the high pressures and the high angular velocities, this is a highly cavitation prone structure, In order to prevent cavitation, there are one or more grooves in one or both of the end plates. These grooves bleed pressure out of the channels, for example to a lower pressure channel or to a sealing volume between the end piece and the rotor.
Patent IL-158137-A (IL)
Title: Printer assembly having flexible ink channel extrusion
IPC: B41J2/16
Filed: 2003-09-25
Abstract: A method for assembling a modular printhead assembly having an ink delivery member and a plurality of printhead modules received in a channel at a predetermined pitch is disclosed. The method includes the steps of flexing the channel apart at a first location to enable receipt of a first printhead module into the channel at the first location, the step of flexing being performed against a pivot point located along a centerline of an underside of the channel; and flexing apart a first capping device to enable pushing of the first capping device over the first printhead module.
Patent IL-176547-A (IL)
Title: 1,3,5-trisubstituted 4,5 - dihydro - 1h - pyrazole derivatives having cb1 - antagonistic activity
IPC: C07D231/06
Filed: 2006-06-26
Abstract: The present invention relates to 1,3,5-trisubstituted 4,5-dihydro-1 H-pyrazole derivatives as CB1 antagonists, to methods for the preparation of these compounds and to novel intermediates useful for the synthesis of said pyrazole derivatives. The invention also relates to the use of a compound disclosed herein for the manufacture of a medicament giving a beneficial effect. The compounds have the general formula (I) wherein the symbols have the meanings given in the specification.
Patent IL-184413-A (IL)
Title: Monitoring system
Inventor: JENKINS DAVID JOHN
Filed: 2007-07-04
Abstract: A monitoring system is disclosed, suitable particularly for a prison or similar environment, comprising a network having at least two computers, one or more condition-sensing and or monitoring devices, the system being arranged to enable any one of the computers to act as a server at any time, comprising a hierarchical list installed on each computer listing the priority by which the computers can become servers and a priority of threads operating on each computer, said priority of threads including a first thread arranged to check whether each other computer is active and a second thread adapted to use the hierarchical list and data determined via the first thread to determine which computer is to be used as a server.
Patent IL-190855-A (IL)
Title: Switchgear
IPC: H01R/
Filed: 2008-04-14
Abstract: The invention relates to a switchgear (1), preferably a circuit breaker, especially a fault-current circuit breaker and/or a line safety switch. Said switchgear comprises at least one connecting terminal (2) with one connecting area (3) for receiving at least one terminal lead (4), preferably having a rectangular cross-section, especially of a contact (5) of a busbar (6). The aim of the invention is to facilitate a simple, straightforward and rapid installation or wiring of the switchgear, especially without tools such as, e.g., a screwdriver. For this purpose, the connecting terminal (2) comprises at least one spring (7) for applying a contact pressure which is effective in the direction of a closed position of the connecting area (3).
Patent IL-195834-A (IL)
Title: Compositions comprising a plurality of multi-layer pellets and use thereof
IPC: A61K/
Filed: 2008-12-10
Abstract: Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided.
Patent IL-199749-A (IL)
Title: Method for lithium exchange reactions
Filed: 2009-07-07
Abstract: The present invention relates to a process for lithium exchange reactions comprising mixing at least two fluids in a microreactor having at least two injection points.
Patent IL-204939-A (IL)
Title: Blast-resistant barrier
Filed: 2010-04-08
Abstract: A blast-resistant barrier comprising a plurality of units each including a panel having a thickness of greater than 20 to less than 40 millimeter is disclosed. The panel is in the form of a monolithic polycarbonate sheet or laminate that is positioned vertically between the source of a blast and the blast target, the laminate including at least two polycarbonate sheets and an optional image layer interposed therebetween. The panel is fixedly attached to a frame which is firmly embedded in concrete in a manner calculated to provide stiffness sufficient to absorb and withstand external forces resulting from said blast. In a preferred embodiment the panel includes at least two polycarbonate sheets laminated one to the other, optionally including an image layer interposed therebetween. In an additional embodiment, the frame is anchored securely to the target enabling dissipation of the blast force through the target's structure. The height of the blast-resistant barrier is preferably proportional to the height of the target.
Patent IL-206397-A (IL)
Title: Compounds exhibiting cytotoxic activity, pharmaceutical compositions containing same and uses thereof in the manufacture of medicaments for treating tumors
Inventor: VICENTE ALBERTO RODRIGUEZ
IPC: A61K/
Filed: 2010-06-15
Abstract: A compound of general formula (I)   
wherein A, Y, W, R 1 , R 2 , R 3 , R 4 , R 5 , and R 6  take various meanings for use in the treatment of cancer.
Patent IL-212701-A (IL)
Title: Humanized anti-cd19 antibody
IPC: C07K/
Filed: 2011-05-05
Abstract: The present invention provides humanized, chimeric and human anti-CD19 antibodies, anti-CD19 antibody fusion proteins, and fragments thereof that bind to a human B cell marker. Such antibodies, fusion proteins and fragments thereof are useful for the treatment and diagnosis of various B-cell disorders, including B-cell malignancies and autoimmune diseases. In more particular embodiments, the humanized anti-CD19 antibodies may comprise one or more framework region amino acid substitutions designed to improve protein stability, antibody binding and/or expression levels. In a particularly preferred embodiment, the substitutions comprise a Ser91Phe substitution in the hA19 VH sequence.
Patent IL-229831-A (IL)
Title: Use of substituted aminopurines for the preparation of medicaments
IPC: A61K/
Filed: 2013-12-05
Abstract: Provided herein are Aminopurine Compounds, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
Patent IL-247231-A (IL)
Title: Composition for treating non-alcoholic fatty liver disease (nafld)
Filed: 2016-08-11
Abstract: The present invention provides a compound of Formula (I) or pharmaceutical acceptable thereof, wherein 'R' is herein described. In addition, the invention relates to composition comprising effective therapeutic amount of compound of formula (I) and methods of using the compounds for treating or prevention disorder such as nonalcoholic fatty liver disease (NAFLD) including fatty liver (steatosis), nonalcoholic steatohepatitis (NASH), and cirrhosis (advanced scarring of the liver).
[WO2014174524A1]
Patent JP-H01164309-A (JP)
Title: Cushion and method for its manufacture
Inventor: UIRIAMU TABURIYUU UINGU
IPC: B29C39/10
Filed: 1988-04-22
Abstract: PURPOSE: To easily provide an ordered cushion without requiring mutually adhering foam parts and using or applying another adhesive for adhering the foam part to a film, by allowing to adhere each of foam bodies at an arbitrary common border of a foam part and a flexible film part using a material for manufacturing the foam body. CONSTITUTION: This cushion 10 is equipped with an outer cover in a form of a flexible film 20 and a foam body 22 set in and adhered to the flexible film. The flexible film is to be in a form of plastic plate, cloth, plastic covered cloth, leather, an assembly of these materials, etc. The foam body 20 is equipped with foam parts 26 and 28 with different foam density, hardness, or compression rate. Foam parts 26 and 28 are adhered mutually on an arbitrary common border by using a material same as that of the foam parts. Each of foam parts 26 and 28 is adhered with the flexible film 20 on an arbitrary common border between each of foam parts and the flexible part 20 by using a material same as that of the foam parts.
Patent JP-S63266900-A (JP)
Title: Component suction device
Inventor: AJIKI NAOJI
IPC: H01L21/68
Filed: 1987-04-24
Abstract: PURPOSE:To eliminate a need for an electrical wiring operation to a suction device from the outside by a structure wherein a large-bore nozzle or a small-bore nozzle is retained at an upper dead point or a lower dead point for a movement and the retention of the nozzle is released by giving a moving force to a rod. CONSTITUTION:When a rod 5 is lowered by an elongation action of a fluid-pressure cylinder 7, a large-bore nozzle 2 is shifted to a protruding direction with reference to a small-bore nozzle 1; it the large-bore nozzle reaches a lower dead point for a movement, permanent magnets 4 are attracted to side plates 8; the large-bore nozzle 2 is retained in. the position and is in a state to attract a large-sized component. It the rod 5 is raised from the state by a contraction action of the liquid-pressure cylinder 7, the retention of the large-bore nozzle 2 by the permanent magnets 4 is released; at the same time, the large-bore nozzle 2 is shifted to a retreating direction. When the nozzle reaches the upper dead point for the movement, the permanent magnets 4 are attracted to a flange 3A of a head shaft 3; the large-bore nozzle 3 is retained in the position and is in a state to attract a small-sized component. By this setup, because an electromagnet is not required, it is possible to eliminate a need for an electrical wiring operation to a suction device from the outside.
Patent JP-S59225663-A (JP)
Title: Sequential multiple address device
Inventor: WADA YOSHINORI
IPC: H04N1/00
Filed: 1983-06-07
Abstract: PURPOSE:To improve the utilizing efficiency by providing a transmission control means transmitting picture information in succession to other picture information while keeping the line when the latter picture information set with the same address as the former picture information exists at the point of time of the completion of the transmission of the former picture information. CONSTITUTION:The device is provided with a network control circuit 1f controlling a transmission network such as telephone line network so as to establish or disconnect the transmission line, a scanner 1a, a printer 1b, a buffer 1c, a code companding circuit 1d, an MODEM 1e, and a CPU (central processing unit) controlling respectively the network control circuit 1f and a management information adding circuit 1g. Then after the transmission processing is finished, table search is applied again so as to check whether or not a transmission file having the same address exists. If such transmission file exists and if the searched transmission file is in the state of the presence of transmission request, whether or not the mode is a time designation transmission mode is discriminated, the processing restores to the transmission processing and the said transmission file is transmitted.
Patent JP-S5725556-A (JP)
Title: Chain adjuster
Inventor: YOKOKI YOUNOSUKE
IPC: F16H7/08
Filed: 1980-07-22
Abstract: PURPOSE: To simplify the structure of a chain adjuster by wedging a wedge piece to be easily slided to push a chain on the backside of an adjuster arranged along the chain as using a spring for preventing the chain against fluttering caused by the loosening of the chain.  
     CONSTITUTION: An adjuster 6 is pivotted to be turnable on a machine frame 8 by a shaft 7 in its lower basic end, and arranged along a chain 5. A stay 10 is pivotted by a shaft 9 in its basic end, and applied to the machine frame 8 at its top. When a crank shaft 1 is rotated, a cam shaft 3 is driven via the chain 5. When the chain 5 is used for a long duration, it is extended and loosened. At this stage, a wedge piece 12 is pulled by a spring 14 and shifted downward. It is wedged between the stay 10 and a guide 13, and the adjuster 6 is pushed to the side of the chain 5 to tighten the chain. The wedge piece 12, once wedged in, cannot be returned upward by the work of wedging. Even if the driving torque is changed, the adjuster 6 cannot be pushed back, and the chain 5 is prevented against loosening and fluttering. 
     COPYRIGHT: (C)1982,JPO&Japio
Patent JP-S584016-A (JP)
Title: Fabrication of legs for elevating type offshore working platform
Inventor: TAKIZAWA AKIRA
IPC: E02B17/00
Filed: 1981-06-26
Abstract: PURPOSE:To eliminate the needs for the towing of a working platform body and the installation of offshore crane by using a system in which legs are stacked up on a foundation leg portion by utilizing the working platform body, a jack mechanism, and the foundation leg portion. CONSTITUTION:A platform 1 is built up on the bottom 22 of a dock through blocks 23, and a foundation leg portion 3 is provided in a jack house 2. Then, legs 16 are placed on fixed rails 6-9 through a truck 17, and the platform 1 is raised up to the upper end of the foundation leg portion 3 by operating the jack mechanism inside the dock. Then, the legs 16 are moved to right above the foundation leg portion 13 through temporary rails 10-13 provided, the platform 1 is slightly lowered, leg pipes 3a and 16a are welded, and then the temporary rails 10-13, the truck 17, and the fixed rails 6-9 are removed.
Patent JP-H07309995-A (JP)
Title: Phenolic resin molding material
Inventor: KUSHIDA TAKANORI
IPC: C08L1/02
Filed: 1994-05-16
Abstract: PURPOSE:To obtain a phenolic resin molding material capable of forming a molded product with little odor. CONSTITUTION:A phenolic resin molding material comprises a phenolic resin comprising a novolak resin and a resol resin, the amt. of which is 30 to 90wt.% based on the phenolic resin; and a filler. The filler is pref. a hemp fiber having a fiber length of 0.1 to 5mm.
Patent JP-S60247075-A (JP)
Title: Vacuum pump
Inventor: YONEYAMA MITSUHO
IPC: F04B37/08
Filed: 1984-05-21
Abstract: PURPOSE:To reduce the installation space and to abolish detailed operating condi tions by arranging pump elements for performing evacuation from molecular flow region to viscous flow region in single casing while employing single drive shaft. CONSTITUTION:Suction and delivery ports 22, 23 are provided in the casing 21. Then first pump element 24 comprising a turbo molecular pump is arranged at the suction port 22 side in said casing 21. While second pump element 25 comprosing a seal pump is aranged at the delivery side of first pump element 24. Furthermore, third pump element 26 comprising a screw pump is arranged at the delivery side of second pump element 25. Said pump elements 24-26 are rotated through common drive shaft 34 which is rotated by means of a terminalboard motor 35.