baber/WOPTO huggingface dataset:
Patent AU-2019271283-A1 (AU)
Title: Systems, devices, and methods for the accurate deployment and imaging of an implant in the prostatic urethra
Inventor: BLY AUSTIN MICHAEL
IPC: A61F2/966
Filed: 2019-05-16
Abstract: Systems, devices, and methods are provided for the delivery of an implant into the prostatic urethra. Embodiments of delivery systems can include a delivery device for insertion into the patient and a proximal control device for use in controlling release of the implant from the delivery device.
Patent AU-2019284255-A1 (AU)
Title: Transgenic chicken with functionally deleted IgY CH1 coding sequence
Inventor: LEIGHTON PHILIP A
IPC: C12N15/85
Filed: 2019-06-05
Abstract: Provided herein is a transgenic chicken comprising a genome having an endogenous immunoglobulin heavy chain gene in which the IgY CH1 coding sequence is functionally deleted. In certain embodiments, in B cells of the chicken the endogenous immunoglobulin heavy chain gene comprises: (a) a functional immunoglobulin heavy chain gene comprising, in operable linkage, a nucleic acid encoding an antibody heavy chain variable domain and a constant region coding sequence in which the IgY CH1 coding sequence is functionally deleted; and (b) a plurality of pseudogenes that are operably linked to said functional immunoglobulin heavy chain gene and that donate, by gene conversion, nucleotide sequence to the nucleic acid encoding the variable domain of (a), wherein the pseudogenes are upstream of the nucleic acid encoding an antibody heavy chain variable domain of (a).
Patent AU-2019285354-A1 (AU)
Title: Substance having affinity for antibody, and compound or salt thereof having bioorthogonal functional group
Inventor: MATSUDA YUTAKA
IPC: C07K16/00
Filed: 2019-06-14
Abstract: The present invention provides art that enables modification of an antibody, particularly regioselective modification of an antibody. More specifically, the present invention provides a substance having affinity for an antibody, and a compound or salt thereof having a bioorthogonal functional group, which are represented by formula (I): A-L-E-B (where, A is a substance having affinity for an antibody, L is a divalent group containing a leaving group, E is a divalent group containing an electrophilic group that (i) is linked to the leaving group and (ii) has a capacity for reacting with a nucleophilic group in the antibody, B is a bioorthogonal functional group, and the leaving group has a capacity for separating from and leaving E due to a reaction between the nucleophilic group and the electrophilic group).
Patent AU-2019294572-A1 (AU)
Title: Folate preparations
Inventor: ULMANN MARTIN
IPC: A61P17/14
Filed: 2019-07-01
Abstract: The present invention relates to preparations of folate salts and their topical use for the treatment of epithelial tissue irritations and skin disorders.
Patent AU-2019296826-A1 (AU)
Title: Modified Y type molecular sieve, catalytic cracking catalyst having same, and preparation method therefor and application thereof
Inventor: YUAN SHUAI
IPC: B01J29/08
Filed: 2019-06-27
Abstract: A modified Y type molecular sieve, and a preparation method therefor and an application thereof. The calcium content of the modified Y type molecular sieve is about 0.3-4 wt% in terms of calcium oxide; the rare earth content is about 2.7 wt% in terms of rare earth oxide; the sodium content is not more than about 0.5 wt% in terms of sodium oxide; the total pore volume is about 0.33-0.39 mL/g, wherein the pore volume of secondary pores having a pore diameter of 2-100 nm occupies about 10-25% of the total pore volume; the lattice constant is about 2.440-2.455 nm; the content of non-framework aluminum occupies no higher than about 20% of the total aluminum content; the lattice collapse temperature is not less than about 1050°C; moreover, the ratio of B acid content to L acid content is no less than about 2.30 in the total acid content measured using a pyridine adsorption infrared method at the temperature of 200°C. The modified Y type molecular sieve and a catalytic cracking catalyst having same have higher heavy oil conversion activity and lower coke selectivity during heavy oil fluid catalytic cracking and can obtain a higher gasoline yield and an isomeric C4 yield, and the obtained gasoline has a higher isohydrocarbon content.
Patent AU-2019313083-A1 (AU)
Title: High-sweetening-content stevia plant and method for screening same
Inventor: HIRAI Tadayoshi
IPC: C12Q1/6876
Filed: 2019-07-30
Abstract: The present invention provides a high-sweetening-content stevia plant having a mutation in a portion corresponding to SEQ ID NO: 1, a method for producing the same, and a screening method for the same.
Patent AU-2019338239-A1 (AU)
Title: Optically brightened latexes
Inventor: DOMINGUEZ CRISTINA
IPC: C08F2/22
Filed: 2019-09-13
Abstract: The present invention relates to a method of preparing an aqueous composition by emulsion polymerization of at least one ethylenically unsaturated monomer in the presence of at least one water-soluble diaminostilbene disulphonic optical brightener, as well as to the aqueous composition obtainable by said method, the use of said aqueous composition for optically brightening of a cellulosic substrate and the cellulosic substrate treated with the aqueous composition.
Patent AU-2019343965-A1 (AU)
Title: Targeting moiety-drug grafted immune cell compositions and methods of use
Inventor: WON YOUNGWOOK
IPC: C07K16/30
Filed: 2019-09-20
Abstract: Surface-engineered immune cells, such as natural killer cells, grafted with targeting moiety-drug complexes. The present invention combines chemotherapy and immunotherapy by engineering the immune cells to target specific tumor cells through antigen recognition and deliver potent chemotherapeutic agents, thereby destroying the tumor cells. The surface-engineered immune cells may be prepared using a one-step method. The present invention also provides kits for preparing the surface-engineered immune cells.
Patent AU-2019353002-A1 (AU)
Title: Azithromycin and roxithromycin derivatives as senolytic drugs
Inventor: SOTGIA FEDERICA
IPC: A61P31/04
Filed: 2019-10-02
Abstract: This disclosure describes the use of azithromycin, roxithromycin, and telithromycin, including derivatives thereof, as senolytic drugs. BrdU was used to induce senescence in model human fibroblast cell lines. Also disclosed are methods for screening compounds for senolytic activity. The SRB assay was used to measure cell viability through protein content. Azithromycin roxithromycin, and telithromycin, clinically-approved pharmaceuticals, were found to be senolytic drugs. However, the closely-related parent compound, erythromycin, showed no senolytic activity. Azithromycin strongly induced both aerobic glycolysis and autophagy in human fibroblasts, but showed bi-phasic effects including on mitochondrial oxygen consumption rates with inhibitory activity at 50 μΜ and stimulatory activity at 100 μΜ. The xCELLigence real-time assay system showed that azithromycin preferentially targets senescent cells, removing approximately 97% (nearly a 25-fold reduction in senescent cells).
Patent AU-2019359416-A1 (AU)
Title: Method for radially aligning wheelsets of rail vehicles
Inventor: NAUMANN JOHN OLIVER
IPC: B61F5/38
Filed: 2019-10-11
Abstract: The invention relates to a method for radially aligning wheelsets of rail vehicles relative to a coordinate system of a wheelset diagnosis tool and/or wheelset machine tool, which method can be implemented quickly with sufficient precision and comprises the following steps: a) positioning the wheelset at a working position of the tool; b) defining a tool-side coordinate system in an assumed wheel centre point of each wheel, where an X-axis adopts a vertical extent, a Y-axis adopts a horizontal extent and a Z-axis describes the resulting depth extent of the wheel; c) measuring the distance of the wheel backs with respect to one another and defining the Z-position = 0 on each wheel back; d) defining a unique Z-position for each measuring point; e) positioning each measuring sensor at the specified Z-position; f) measuring the X-position of each measuring point; g) aligning the wheelset by vertically displacing one of the wheels in order to match the X-positions of the measuring points of two wheels.
Patent AU-2019374703-A1 (AU)
Title: Cholix-derived carriers for oral delivery of heterologous payload
Inventor: HUNTER THOMAS CARL
IPC: A61K47/64
Filed: 2019-09-11
Abstract: The present disclosure provides delivery constructs comprising a carrier coupled to a heterologous payload, wherein coupling of the carrier to the payload can result in transportation of the payload (e.g., a therapeutic payload) into and/or across intact polarized epithelial cells (e.g., epithelial cells of the gut of a mammal). The delivery construct can be part of a pharmaceutical composition that can be orally administered to a subject to provide for improved, effective therapies for treatment of, e.g., inflammatory diseases or autoimmune diseases.
Patent AU-2019384619-A1 (AU)
Title: Method and device for positioning and/or handling carcasses and/or carcass parts during the slaughter of animals on an industrial scale
Inventor: JACOBS THOMAS GERARDUS MARIA
IPC: A22B7/00
Filed: 2019-11-21
Abstract: The present invention relates to a device for automatically positioning and/or handling and/or transporting a stunned animal or a carcass and/or a carcass part of a slaughtered animal during the slaughter process of animals on an industrial scale, comprising: a controlled first robotic manipulator with at least four axis, at least one suction element and/or at least one mechanical meat gripper for contacting a surface of the stunned animal or carcass and/or carcass part, an extractor connected to the at least one suction element for performing a suction effect in the suction element and/or an actuator connected to the at least one meat gripper for making the meat gripper gripping a part of the stunned animal, the carcass or the carcass part, and at least one controller for controlling the robotic manipulator, the extractor and/or the actuator.
Patent AU-2019388106-A1 (AU)
Title: Botulinum toxin-stabilizing liquid composition
Inventor: KIM WANSEOP PAUL
IPC: A61K47/20
Filed: 2019-11-29
Abstract: The present invention relates to a botulinum toxin-stabilizing liquid composition having the effect of improving the stability of botulinum toxin, a method for preparing same, and a pharmaceutical composition containing the stabilizing liquid composition and having improved stability of botulinum toxin. According to the present invention, since the activity of liquid botulinum toxin is maintained for a long time even at room temperature, there are advantages of excellent storage stability and conservation stability and easy administration.
Patent AU-2019401805-A1 (AU)
Title: Treatment of produced hydrocarbons
Inventor: HAUG INGVILD JOHANNE
IPC: C10G29/00
Filed: 2019-12-20
Abstract: A method for managing metal naphthenates in produced hydrocarbons. The method comprises injecting acid and/or sour gas into produced hydrocarbons in a production well, flowline or riser, to thereby control the pH of fluids contained in the produced hydrocarbons.
Patent AU-2019416045-A1 (AU)
Title: Pump head for a peristaltic pump
Inventor: WANG RUOYA
IPC: A61M5/142
Filed: 2019-12-19
Abstract: Pump heads for peristaltic pump assemblies are provided. For example, a pump head for a peristaltic pump comprises an occlusion bed, a rotor guide, a rotor assembly positioned between the occlusion bed and the rotor guide, and a pathway for tubing. The pathway comprises an inlet portion, an outlet portion, and a connecting portion that connects the inlet and outlet portions. The inlet portion is defined between the occlusion bed and the rotor guide, the outlet portion is defined between the occlusion bed and the rotor guide, and the connecting portion is defined between the occlusion bed and the rotor assembly. Further, the occlusion bed is movable with respect to the rotor guide and the rotor assembly. In exemplary embodiments, the pump head urges fluid flow through the tubing to supply a cooling fluid to a medical probe assembly for delivering energy to a patient's body.
Patent AU-2019416187-A1 (AU)
Title: Highly accurate de novo polynucleotide synthesis
Inventor: PECK BILL JAMES
IPC: C07H21/04
Filed: 2019-12-23
Abstract: Methods, systems, compositions, and devices for the manufacturing of high-quality building blocks, such as polynucleotides, are described herein. Processes described herein provide for efficient washing of residual reagents, solvents, or byproducts from previous synthetic steps to allow for the generation of polynucleotides with low error rates. Processes described herein also provide for reduction in deletion rates during chemical nucleic acid synthesis. Further, methods and devices described herein allow for the rapid construction and assembly of large libraries of highly accurate polynucleotides.
Patent AU-2019428636-A1 (AU)
Title: Memories of fluidic dies
Inventor: NG BOON BING
IPC: B41J2/045
Filed: 2019-02-06
Abstract: In some examples, a fluid dispensing device component includes a plurality of fluidic dies each comprising a memory, a plurality of control inputs to provide respective control information to respective fluidic dies of the plurality of fluidic dies, and a data bus connected to the plurality of fluidic dies, the data bus to provide data of the memories of the plurality of fluidic dies to an output of the fluid dispensing device component.
Patent AU-2019445991-A1 (AU)
Title: Heat Storage System
Inventor: MURATA KENTA
IPC: F24H4/02
Filed: 2019-05-10
Abstract: This thermal storage system is provided with: a compressor for compressing a refrigerant; a thermal storage tank for storing a heat medium; a heat exchange means that is disposed outside the thermal storage tank and is for heating the heat medium using the heat from the refrigerant compressed by the compressor; a thermal storage circuit that has a feed passage for feeding the heat medium flowing out from the thermal storage tank to the heat exchange means, a return passage for returning the heat medium heated by the heat exchange means to the thermal storage tank, and a pump for circulating the heat medium; and a control means that is capable of performing an initial operation in which the operation frequency of the compressor is controlled at an early stage of an thermal storage operation in which the heat medium heated by the heat exchange means is stored in the thermal storage tank. The initial operation includes a first operation in which the operation frequency is kept at a first frequency and a second operation in which the operation frequency is kept at a second frequency that is higher than the first frequency after the first operation.
Patent WO-2021081596-A1 (WO)
Inventor: SCHEINER RUPERT CHRISTIAN
IPC: A61M16/06
Filed: 2020-10-30
Abstract: A patient interface kit to deliver a flow of air at a positive pressure with respect to ambient air pressure to an entrance to a patient's airways including at least the entrance of a patient's nares while the patient is sleeping. The patient interface comprising: a nasal cushion having a nasal cushion opening; a mouth cushion having a mouth cushion opening, the mouth cushion including a flexible joint, positioned above the mouth opening, to selectively connect the nasal cushion to the mouth cushion; and a positioning and stabilizing structure to provide a force to hold the nasal and/or mouth seal-forming structures in a therapeutically effective position on a patient's head, the positioning an stabilizing structure including a nasal headgear including upper straps or conduits and a mouth headgear including lower straps, the mouth headgear being selectively connected to the nasal headgear.
Patent AU-2020204050-A1 (AU)
Title: A method of operating a gaming system, an electronic gaming system and an electronic game controller
Inventor: Sanders Liam
IPC: A63F9/24
Filed: 2020-06-17
Abstract: An electronic method of operating a gaming system 
comprising a display, a game controller, and a memory 
5 storing symbol data is disclosed. The method comprises: 
selecting, using the game controller, a plurality of 
symbols from the symbol data; 
displaying the selected symbols on the display at 
respective ones of a plurality of symbol display positions 
10 arranged in a plurality of columns on the display, 
upon the selected symbols including one or more 
designated symbols, retaining, using the game controller, 
each designated symbol for a subsequent game round at the 
symbol display position at which the designated symbol was 
15 displayed; 
in the subsequent game round, selecting, using the 
game controller, a plurality of symbols from the symbol 
data; 
upon a further designated symbol being selected for 
20 display at a display position at which a designated symbol 
is retained, modifying, using the game controller, the 
retained designated symbol to incorporate a multiplier; 
and 
upon the selected symbols in the subsequent game 
25 round corresponding to a winning outcome incorporating the 
modified retained designated symbol, making, using the 
game controller, an award of an award value corresponding 
to the winning outcome multiplied by the multiplier.  
12370633_1 (GHMatters) P100870.AU.3 17/06/20
Patent AU-2020248826-A1 (AU)
Title: Radio frequency front end circuit and mobile terminal
Inventor: HSIEH CHENG-NAN
IPC: H04B7/06
Filed: 2020-03-18
Abstract: Provided in the present disclosure are a radio frequency front end circuit and a mobile terminal. The circuit comprises: a gating switch, connected separately to a first antenna, a second antenna and a radio frequency circuit module; a double-pole, double-throw switch, connected separately to the gating switch, a third antenna, a fourth antenna and a first radio frequency circuit; the radio frequency circuit module being connected to a first target antenna of the first antenna and the second antenna by means of the gating switch, and receiving and/or transmitting a signal by means of the first target antenna; or, the radio frequency circuit module being connected to a second target antenna of the third antenna and the fourth antenna by means of the gating switch and the double-pole, double-throw switch, and receiving and/or transmitting a signal by means of the second target antenna; the first radio frequency circuit being connected to one of the third antenna and the fourth antenna by means of the double-pole, double-throw switch.
Patent AU-2020260485-A1 (AU)
Title: Gene therapies for lysosomal disorders
Inventor: ABELIOVICH ASA
IPC: C07K14/00
Filed: 2020-10-29
Abstract: The disclosure relates, in some aspects, to compositions and methods for treatment of 
diseases associated with aberrant lysosomal function, for example Parkinson's disease (PD) and 
5 Gaucher disease. In some embodiments, the disclosure provides expression constructs 
comprising a transgene encoding beta-Glucocerebrosidase (GBA) or a portion thereof alone or 
in combination with one or more PD-associated genes. In some embodiments, the disclosure 
provides methods of Parkinson's disease by administering such expression constructs to a 
subject in need thereof.
Patent AU-2020267170-A1 (AU)
Title: Methods and formulations using lithium to treat gout inflammatory arthropathy and pain
Inventor: GANIO CARL
IPC: A61K33/00
Filed: 2020-06-19
Abstract: The present inventive concept provides lithium-based formulations and methods 
of using the same for the prevention and treatment of inflammatory conditions, gout, joint 
disease, pain and symptoms thereof. The present inventive concept also provides kits for 
preventing or treating inflammatory conditions, gout, joint disease and pain, including 
acute and chronic pain.
Patent AU-2020275069-A1 (AU)
Title: Container for storing and serving frozen confectionery items
Inventor: DIKS-WARMERDAM LEONIE MARTINE
IPC: F25D3/06
Filed: 2020-05-05
Abstract: A thermally insulated container for storing and serving frozen confectionery items, wherein the container is preferably arranged to be removably mounted within a service cart, such as an inflight service cart.
Patent AU-2020283503-A1 (AU)
Title: Data layer architecture, open data layer module and translation layer
Inventor: ROCKWELL DOUGLAS P
IPC: G06F16/2452
Filed: 2020-05-27
Abstract: A computing network data layer architecture or system includes an open data layer module comprising a translation layer. Translation flags are within the translation layer and each flag is associated with a database language of an underlying database that can be coupled architecture or system. The open data layer module is disposed at the lowermost layer of the architecture directly above the underlying backend database. The open data layer module allows for a system to replace or modify its backend databases without affecting the higher level visualization framework or user interface such that a user of the system is unaware which database is utilized or after one database has been replaced or swapped for another even though the databases may be disparate hand have different database language requirements.
Patent AU-2020294249-A1 (AU)
Title: Release Apparatus
Inventor: WRIGHT GEOFF
IPC: G01N1/28
Filed: 2020-12-23
Abstract: An apparatus (5) for use in facilitating release of a plurality of items from a condition 
in which the items are supported is disclosed. In at least one form, the apparatus (5) 
comprises first (10) and second (15) planar members each comprising a plurality of 
apertures (201, 202). The first (10) and second (15) planar members being movable 
relative to each other such that the apertures (201, 202) are misaligned in a first 
relative state (see position A in Figure 2) and aligned in a second relative state (see 
position B in Figure 2). The apparatus (5) further comprises an actuator (25) 
operably configured for selective movement of one of the planar members (10, 15) 
from the first relative state, in which the items are supported, to the second relative 
state thereby removing said support for releasing of the items.
Patent AU-2020348701-A1 (AU)
Title: Small sliding multiple plug
Inventor: ZENG GUANGLI
IPC: H01R13/629
Filed: 2020-08-19
Abstract: A multi-path sliding small plug, comprising a housing (1) and several pin insertion holes (2) disposed on the bottom surface of the housing (1). The housing (1) is internally provided with a first insertion pin (6), a second insertion pin (7) and a third insertion pin (8). The first insertion pin (6) is mainly composed of a ground wire support leg (63), a live wire support leg (61) and a neutral wire support leg (62), and the ground wire support leg (63) of the first insertion pin (6) is used as a center point. The second insertion pin (7) is disposed on one side of the center point, the third insertion pin (8) is disposed on the other side of the center point, and the second insertion pin (7) and third insertion pin (8) are each composed of three support legs containing the ground wire support leg. The described multi-path sliding small plug has a small volume and high usage safety, and at the same time, meets the requirements for complying with safety standards and miniaturization-oriented development.
Patent AU-2020372429-A1 (AU)
Title: Compositions and methods for treating glycogen storage disorders
Inventor: GRAY JOHN T
IPC: A61K31/7088
Filed: 2020-10-23
Abstract: The present disclosure relates to compositions and methods useful for treating glycogen storage disorders, such as type II glycogen storage disorder, also referred to herein as Pompe disease. Using the compositions and methods of the disclosure, a patient (e.g., a mammalian patient, such as a human patient) having Pompe disease may be administered a viral vector, such as an adeno-associated viral (AAV) vector, that contains a transgene encoding acid alpha-glucosidase.