Patent SG-11201408423X-A (SG)
Title: ACRYLAMIDE COMPOUNDS AS HISTAMINE H<sb>3</sb> RECEPTOR LIGANDS
Inventor: NIROGI RAMAKRISHNA
IPC: C07D211/46
Filed: 2012-12-05
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 27 February 2014 (27.02.2014) WIPOIPCT (10) International Publication Number WO 2014/030170 A1 (51) International Patent Classification: C07D 401/12 (2006.01) A61K31/445 (2006.01) C07D 211/46 (2006.01) A61P 25/00 (2006.01) (21) International Application Number: PCT/IN2012/000796 (22) International Filing Date: 5 December 2012 (05.12.2012) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 3464/CHE/2012 23 August 2012 (23.08.2012) IN (71) Applicant: SUVEN LIFE SCIENCES LIMITED [IN/IN]; Serene Chambers, Road - 5, Avenue - 7, Banjara Hills, Hyderabad 500 034, Andhra Pradesh (IN). (72) Inventors: NIROGI, Ramakrishna; Suven Life Sciences Limited, Serene Chambers, Road - 5, Avenue - 7, Banjara Hills, Hyderabad 500 034, Andhra Pradesh (IN). SHINDE, Anil, Karbhari; Suven Life Sciences Limited, Serene Chambers, Road - 5, Avenue - 7, Banjara Hills, Hyderabad 500 034, Andhra Pradesh (IN). DWARAMPUDI, Adi, Reddy; Suven Life Sciences Limited, Serene Chambers, Road - 5, Avenue - 7, Banjara Hills, Hyderabad 500 034, Andhra Pradesh (IN). JASTI, Venkateswarlu; Suven Life Sciences Limited, Serene Chambers, Road - 5, Avenue - 7, Banjara Hills, Hyderabad 500 034, Andhra Pradesh (IN). (74) Agents: SUBRAMANIAM, Hariharan et al.; Sub- ramaniam & Associates, E-556, Greater Kailash-II, New Delhi 110 048 (IN). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(H)) Published: — with international search report (Art. 21(3)) — with amended claims and statement (Art. 19(1)) (54) Title: ACRYLAMIDE COMPOUNDS AS HISTAMINE H 3 RECEPTOR LIGANDS o l> T-H o m o (i) (57) Abstract: The present invention relates to novel acrylamide compounds of formula (I), and their pharmaceutically acceptable O salts and process of their preparation. (The chemical formula should be inserted here.) The compounds of formula (I) are useful in CJ the treatment of various disorders that related to Histamine H3 receptors.