baber/WOPTO huggingface dataset:
Patent WO-2020242795-A1 (WO)
Title: A method for treating cancer with an oral dosage form of an estrogen receptor-alpha inhibitor
Inventor: XIAO JIANJUN
IPC: A61K31/4439
Filed: 2020-05-15
Abstract: The present invention relates to pharmaceutical compositions comprising an inhibitor of human ERα, and methods of cancer therapy using the ERα inhibitor. In particular, described herein are dosages of H3B-6545 with defined pharmacokinetic (PK) profiles that allow the inhibitor to be efficaciously and safely administered to a human subject in need thereof.
Patent WO-2020236955-A1 (WO)
Title: Solar power system for vehicles
Inventor: WRIGHT ALBERT
IPC: H02S10/40
Filed: 2020-05-20
Abstract: Systems and methods directed to a solar electric system for use in freight systems. In some embodiments, a solar power system can be configured to provide power to a refrigerated truck trailer. For example, a solar power system can be composed of a solar panel package that can include solar cell layer(s), conductive material(s), and support portion(s).
Patent WO-2020198759-A1 (WO)
Inventor: ASKEW TIMOTHY
IPC: A61J1/00
Filed: 2020-05-22
Abstract: An eye drop medication kit with simplified SIG label and method of use for pre-operative and post-operative treatment using a simplified data-based representation of the desired dosage schedule incorporating a unique identifier system associated with a given dosage schedule and a desired eye drop formulation.
Patent WO-2020243585-A1 (WO)
Inventor: ECHOLS MICHAEL
IPC: C07D209/14
Filed: 2020-05-29
Abstract: A method that may be used in the imaging of tissues or subjects includes flushing a tissue or subject with a solution, preserving the tissue or subject, and then introducing an imaging contrast agent into the tissue or subject. After these actions, the tissue or subject may be imaged.
Patent WO-2020247562-A1 (WO)
Inventor: HOWELL MARGARET A
IPC: A61B46/10
Filed: 2020-06-04
Abstract: A pocket and drape system which provides multiple (e.g., at least two) sterile fields and the methodology for employing said system is provided. The system includes first and second base drape materials each having upper and lower edges edge both extending in a longitudinal direction and first and second side edges both extending in a transverse direction. The first base drape material and the second base drape material also each include a longitudinal fold line. A first zone of pockets is present on a surface of the first base drape material and a second zone of pockets is present on a surface of the second base drape material. The manner in which the base drape materials are folded and joined to each other during assembly (e.g., before sterilization) maintains the sterility of the first and second zone of pockets until each zone is ready for use during a medical procedure.
Patent WO-2020257070-A1 (WO)
Inventor: ZHAO YANNAN
IPC: G01N27/414
Filed: 2020-06-12
Abstract: Provided is a device, including a conductive channel and a number of polymerase molecules bound thereto, wherein the number is between one and five and the conductive channel is to detect incorporation of a nucleotide comprising a charge tag into a nascent polynucleotide by the polymerase, and each of the one or more polymerase molecules includes a hexahistidine tag, the conductive channel includes a multivalent nickel-nitrolotriacetic acid complex, and the hexahistidine tag is bound to the multivalent nickel-nitrolotriacetic acid complex. Also provided are a method of attaching a polymerase to a conductive channel of a device and a method of using the device.
Patent WO-2020257731-A1 (WO)
Inventor: SIDRANE JENNY
IPC: C12P19/34
Filed: 2020-06-20
Abstract: Provided herein are combination therapies involving co-expression of an E2 subunit of a branched-chain alpha-keto acid dehydrogenase (BCKDH) from a skeletal muscle-targeted rAAV.hDBT vector and a liver-targeted rAAV.hDBT vector. Also provided herein are combination therapies wherein an E1a and/or an E1b subunit of the BCKDH complex is expressed from muscle and/or liver following rAAV-mediated delivery targeted to these tissues. Further provided is a pharmaceutical composition comprising a rAAV as described herein in a formulation buffer, and a method of treating a human subject diagnosed with MSUD.
Patent WO-2021011307-A1 (WO)
Inventor: XIE TINGJUN
IPC: G11C11/409
Filed: 2020-07-09
Abstract: A system includes a plurality of memory devices and a processing device (e.g., a controller), operatively coupled to the plurality of memory devices. The processing device is to detect a power-on of the system and determine a read-retry trigger rate (TR) of a subset of codewords of the plurality of memory devices during a time interval after an initialization of the memory component. The processing device is further to determine whether the TR satisfies a threshold criterion. In response to the TR not satisfying the threshold criterion, the processing device is to initialize a full-memory refresh of the plurality of memory devices.
Patent WO-2021026046-A1 (WO)
Inventor: LEWIS BENJAMIN
IPC: A61K35/02
Filed: 2020-08-02
Abstract: Described herein are methods useful for the treatment of cancers in a canine subject with a pharmaceutical compositions comprising HD AC inhibitors, Rapamycin, Dasatinib, Lapatinib, Trametinib, Vorinostat, Imatinib, Crizotinib, Sorafenib, and combinations thereof. Also described herein are methods for identification of subjects with cancers that will benefit from administration of the pharmaceutical compositions comprising HD AC inhibitors, Rapamycin, Dasatinib, Lapatinib, Trametinib, Vorinostat, Imatinib, Crizotinib, Sorafenib, and combinations thereof. In certain aspects, the methods described herein further comprise administering a therapeutically effective amount of at least one additional anti-cancer agent.
Patent WO-2021034510-A1 (WO)
Title: Apparatus and method for cutting glass laminate
Inventor: LEE WOO JIN
IPC: C03B33/10
Filed: 2020-08-07
Abstract: Provided are an apparatus and method for cutting a glass laminate. The apparatus comprises a first and second part spaced apart from each other by a first gap, a first guide block and a second guide block spaced apart from each other by a second gap, wherein a saw blade is able to pass through first and second gaps, a first fixing unit and second fixing unit, each capable of fixing the respective first guide block and second guide block to the respective first part and second part of the table, and thus defining a space for a glass laminate.
Patent WO-2021046384-A1 (WO)
Title: Tethered, hinged closure
Inventor: LOHRMAN RICHARD D
IPC: B65D41/34
Filed: 2020-09-04
Abstract: A closure includes a cap having a top wall and a skirt perpendicular to the top wall and extending downwardly from the top wall to a lower edge. The skirt includes an inner surface having a sealing formation. A band is concentric with and attached to the lower edge of the skirt by a plurality of frangible members. The band remains coupled to the body of the closure even after being removed from a container.
Patent WO-2021080705-A1 (WO)
Title: Structures and liquids for liquid infused surface structures
Inventor: LI QIUZI
IPC: B05D5/08
Filed: 2020-09-14
Abstract: A structure for use as a liquid impregnated surface (LIS) can include a surface configured to interact with a liquid to retain the liquid to the surface. The liquid can be a low viscosity hydrocarbon. In certain embodiments, the low viscosity hydrocarbon can be polyalphaolefin (PAO) or heptane, for example. Any other suitable low viscosity hydrocarbon is contemplated herein. In certain embodiments, the structure can further include the low viscosity hydrocarbon disposed on the surface.
Patent WO-2021055915-A1 (WO)
Title: Modified t cells and methods of preparing the same
Inventor: DOTTI GIANPIETRO
IPC: A61K35/17
Filed: 2020-09-20
Abstract: Disclosed herein are modified T cells comprising an IL12β p40 subunit. Also disclosed herein are methods of increasing T cell proliferation and/or methods of treating cancer by administering the modified T cells comprising an IL12β p40 subunit.
Patent WO-2021081242-A1 (WO)
Title: Tcp performance model based in-band network telemetry
Inventor: GUO XIANGYI
IPC: H04L45/74
Filed: 2020-10-22
Abstract: Systems and methods for a path selection by a network router are disclosed. The router receives a data packet destined to travel a current path, as identified by a packet header, to a destination router. The router determines whether the current path is the best path of a set of network paths for the data packet to travel to reach the destination router based on telemetry characteristics of a set of network paths. The telemetry characteristics include a bandwidth availability estimate that is a function of one or both of a corresponding path throughput and a corresponding path packet loss rate. In response to determining the current path is not the best path, the router chooses a best path based on the telemetry characteristics of the set of paths and replaces the current path with the best path for travel by the data packet to the destination router.
Patent WO-2021101763-A1 (WO)
Inventor: BARHUDARIAN VIOLET ANNA
IPC: G06F21/44
Filed: 2020-11-11
Abstract: Managing user sessions in a networked computing environment. A method includes, at an identity provider computer system, providing a first id token to a resource provider for an entity. The first id token has therein a first policy check interval having a value defining a period when the first id token should be revalidated. Due to expiration of the first policy check interval, a first refresh token is received from a resource provider computer system that received the first id token. As a result of receiving the first refresh token from the resource provider computer system, the identity provider computer system evaluates conditional access policy for the entity. If the identity provider computer system determines that the conditional access policy for the entity has been met, the identity provider computer system provides a new id token and a new refresh token to the resource provider computer system.
Patent WO-2021118802-A1 (WO)
Inventor: KRIEGER JEFFREY
IPC: F01L3/20
Filed: 2020-11-24
Abstract: An engine head assembly (18) includes a valve seat insert (38) having a valve seating surface (44) defining a center axis, and each of an inner peripheral surface (52) and an outer peripheral surface (56) extending circumferentially around the valve seat center axis. The outer peripheral surface (56) includes an upper section (58) interference-fitted with the engine head (20), and a lower section (60). A stiffness relief channel (62) is formed by a relief cutout (63) in the valve seat insert (38), and extends radially between the lower section (60,160) of the outer peripheral surface (56) and the engine head (20). The stiffness relief channel (62) permits flexing of the valve seat insert (38) to cushion valve seating to prolong engine valve and valve seat insert service life.
Patent WO-2021133597-A1 (WO)
Title: Configurations de tête laser et techniques de traitement de matériaux
Inventor: ZHOU WANG-LONG
IPC: B23K26/06
Filed: 2020-12-16
Abstract: Dans divers modes de réalisation, une tête laser reçoit un faisceau de sortie laser provenant d'un système laser ou d'un résonateur sans utiliser de fibre optique de distribution, et toute asymétrie du faisceau de sortie laser peut être maintenue. La tête laser peut être physiquement rotative pour commander l'orientation du faisceau laser le long d'un trajet de traitement sur une pièce à travailler.
Patent WO-2021133669-A1 (WO)
Inventor: UNUTMAZ DERYA
IPC: G06N20/00
Filed: 2020-12-18
Abstract: A method and system for developing a predictive model for diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in a human are disclosed. The method comprises receiving immune system data for each member of a population comprising healthy humans and humans with ME/CFS; extracting a set of features from the immune system data; and training a machine learning algorithm using the set of features to classify a human as healthy or having ME/CFS to obtain a predictive model. The system comprises a processor; and a memory storing computer executable instructions, which when executed by the processor cause the processor to perform operations of said method.
Patent WO-2021138183-A1 (WO)
Title: Machine learning system for interpreting host phage response
Inventor: COHEN ROB
IPC: G16B5/30
Filed: 2020-12-23
Abstract: A computer implemented method of generating a machine learning model for interpreting host phage response data comprising receiving datasets and labels for a host phage response, training a machine learning model and using this model to estimate the efficacy of a test phage in inhibiting growth of a test bacteria.
Patent WO-2021067994-A1 (WO)
Title: Fluoride-free anticavity oral care compositions
Inventor: BAIG ARIF
IPC: A61K36/185
Filed: 2020-09-30
Abstract: Fluoride-free oral care compositions with an anticaries or anticavity effect. Oral care compositions that are fluoride-free and have an extract from a species in the  Humulus  family. Oral care compositions that are fluoride-free and have an extract from  Humulus lupulus . Oral care compositions that are fluoride-free and have a hops beta acid.
Patent WO-2021150897-A1 (WO)
Title: System and method for real-time fitness tracking and scheduling
Inventor: COYLE TIMOTHY
IPC: G16H20/30
Filed: 2021-01-22
Abstract: A computer system configured to implement a method for real-time fitness tracking and scheduling is described herein. The computer system receives health data, a first health goal for completion during a first time period, and a second health goal for completion during a second time period for a user. A health profile is generated that includes the health data, the first health goal, and the second health goal. The health data is implemented in if-then scenarios to determine a first wellness action for the user to complete during a first time period to achieve the first health goal and a second wellness action for the user to complete during a second time period to achieve the second health goal. A health and wellness program is created for the user based on the first wellness action and the second wellness action.
Patent WO-2021158410-A1 (WO)
Title: Electronic component assembly for a motorcycle assembly
Inventor: LANGLOIS BRIAN K
IPC: B62J9/40
Filed: 2021-01-27
Abstract: A system for a motorized vehicle (10) having a frame (14) and a wheel (18) rotatably coupled to the frame has a first fender housing (154) mounted to the frame, a second fender housing (570) coupled to the first fender housing so that a volume is defined therebetween and an electronic component (552, 554) disposed in the volume.
Patent WO-2021155295-A1 (WO)
Title: Anti-müllerian hormone receptor 2 antibodies and methods of use
Inventor: TUOHY VINCENT K
IPC: A61P35/00
Filed: 2021-01-29
Abstract: Provided herein are anti-Anti-Müllerian Hormone Receptor 2 (AMHR2) antibodies and methods of using such antibodies, for example, in the treatment of cancer.
Patent WO-2021155333-A1 (WO)
Title: Techniques for poll bit trigger enhancement in a wireless communication system
Inventor: KANAMARLAPUDI SITARAMANJANEYULU
IPC: H04L1/16
Filed: 2021-01-31
Abstract: Aspects described herein relate to POLL timer enhancement in fifth generation new radio (5G NR). In an example, the aspects may include determining whether a count of packet data unit (PDU) without POLL associated with a current PDU sequence satisfies a threshold for maximum PDUs without POLL; determining whether a total transmission queue memory exceeds an uplink transmission queue memory threshold; generating a POLL bit based on a determination that the PDU without POLL count associated with the current PDU without POLL in-sequence satisfies the threshold for maximum PDUs without POLL and the total transmission queue memory exceeds the threshold for uplink transmission queue memory; and transmitting, to a network entity, the current PDU with the POLL bit.
Patent WO-2021163688-A1 (WO)
Title: Handpieces for medical and dental devices
Inventor: FRANCO ANDRES
IPC: A61C3/025
Filed: 2021-02-16
Abstract: A handpiece of a medical or dental device allows a user to hold, support, and/or operate the handpiece by placing a portion of the user's hand, such as one or more fingers ( e.g. , the forefinger) through an ergonomic aperture in the handpiece.
Patent WO-2021173760-A1 (WO)
Inventor: VENKATACHARI HARISH
IPC: H04W72/04
Filed: 2021-02-25
Abstract: A user equipment (UE) can connect to an evolved universal terrestrial radio access network (E-UTRAN) new radio (NR) dual-connectivity (EN-DC) network using both a Long Term Evolution (LTE) anchor link and a 5G NR non-anchor link. The UE shares RF chain components (e.g., antennas) between the LTE and NR links. The UE uses various techniques for controlling or modifying NR sounding reference signal (SRS) transmissions and/or LTE operations to avoid interruption on LTE operations due to NR SRS transmissions.
Patent WO-2021178446-A1 (WO)
Inventor: BHUYAN SUDEEPTA
IPC: H04N21/24
Filed: 2021-03-02
Abstract: A method, apparatus, and system for measuring consumption of content data having content for serially presentation is presented. The method comprises generating n random numbers, where n>0, generating a first value Pi at least in part from a cryptographic function of the n random numbers, publishing the first value Pi to a smart contract associated with a blockchain, embedding consumption monitoring data comprising the n random numbers in different temporal locations of the content data and transmitting the content data to a client device for consumption. A client device extracts each of the n random and transmits the extracted n random numbers to the smart contract associated with the blockchain. A smart contract verifies that the n random numbers match the embedded n random numbers and executes a transaction of the smart contract.
Patent WO-2021178899-A1 (WO)
Inventor: PANIGRAHI DIPAK
IPC: A61K31/05
Filed: 2021-03-05
Abstract: Cannabidiol (CBD) based compositions for use in the treatment of angiogenesis in proliferative diabetic retinopathy (PDR) is provided. The invention also relates to methods and compositions for treating conditions associated with lymphangiogenesis using cannabidiol (CBD). Preferably the angiogenesis manifest as abnormal vascular lesions with visual impairment and the angiogenesis is treatment resistant.
Patent WO-2021195065-A1 (WO)
Inventor: BAKER JAY
IPC: B65D43/02
Filed: 2021-03-23
Abstract: A thermoformed packaging container includes a base section having a bottom surface, first and second inner and outer base side walls, and first and second inner and outer base end walls forming a chamber, with at least one outer base one side wall having a plurality of base indentations and protrusions formed therein. A cover section having a top surface, first and second cover side walls, and first and second cover end walls, the cover section adapted to cover the base section when in a closed state, with at least one of the cover side walls having a plurality of cover indentations and protrusions formed therein for engaging with the plurality of base indentations and protrusions. The container also includes a closure mechanism for securing the container in a closed position, wherein the closure mechanism is formed within at least one end wall of the base section and a corresponding end wall of the cover section.
Patent WO-2021202188-A1 (WO)
Title: Catalysts, preparation method thereof, and selective hydrogenation processes
Inventor: SCHMIDT STEPHEN
IPC: C12N15/52
Filed: 2021-03-24
Abstract: The present invention relates to a process for making 1,4-butanediol. The process may include reacting a solution comprising 1,4-butynediol with hydrogen in a presence of an effective amount of a catalyst. The catalyst may include copper.
Patent WO-2021207304-A1 (WO)
Title: Single trip wellbore completion system
Inventor: POIZAT JEREMIE
IPC: E21B43/14
Filed: 2021-04-07
Abstract: A completion string includes at least one isolation packer positioned between well zones of a plurality of well zones, and a sand control assembly and a circulating assembly each disposed uphole of a washdown shoe in the bottom-most well zone. A top well zone includes a return valve assembly, a production packer, and a second circulating assembly and a second sand control assembly downhole of the production packer. The completion string also includes an outer string spanning from the bottom-most well zone to the top well zone, and an inner production string concentrically arranged within the outer string, creating an inner-annulus between the outer string and inner production string. The inner-annulus is continuous from the washdown shoe to the return valve assembly, and the inner production string includes a production valve disposed between the sand control assembly and the circulating assembly in each of the bottom-most and top well zones.
Patent WO-2021207666-A1 (WO)
Title: Systems and methods for packaging instruments or other items with bag making features
Inventor: BAKER RUSSELL
IPC: B65B51/10
Filed: 2021-04-09
Abstract: A bagmaker interoperable with an item processor is disclosed, the bagmaker being configured to produce bags for packaging items for sterilization, such as medical instruments. The bagmaker may include a controller interoperable with a bag production device, the bag production device including a bag cutter and a heat sealer, such that tubing may be sealed and cut, such that a bag of a specified length is formed. Operation of the bagmaker may include identifying tubing corresponding to a bag width of the bag, advancing tubing to correspond with the length of the bag, sealing at least a first end of the tubing, and then advancing and cutting the tubing; ejecting the bag from the bagmaker and retracting remaining uncut tubing, wherein the retraction and ejection may occur contemporaneously or interchangeably in order.
Patent WO-2021211519-A1 (WO)
Title: Disc brake rotor assembly
Inventor: HARRINGTON JONATHAN DAVID
IPC: B60B27/00
Filed: 2021-04-13
Abstract: In one aspect of the present disclosure, a disc brake rotor assembly is provided that includes a disc brake rotor and a wheel hub. One of the disc brake rotor and the wheel hub includes a plurality of pairs of partial keyways and the other of the disc brake rotor and the wheel hub includes intermediate partial keyways configured to fit intermediate the pairs of partial keyways to form keyways. The disc brake rotor assembly further includes a plurality of fasteners configured to be received in the keyways to secure the disc brake rotor and the wheel hub together.
Patent WO-2021211639-A1 (WO)
Title: A solid-state circuit breaker based on a wireless coupling and resonant circuit for mvdc systems
Inventor: LU FEI
IPC: H01H9/54
Filed: 2021-04-13
Abstract: With the fasting growth of renewable energy resources and DC supplied loads, DC electrical systems have been increasingly received attentions all over the world. DC breaker systems play a key role in protection systems for disconnecting sources and loads, and they are also used mainly for removing faulted sections from the system accurately and reliably. Solid state DC breakers benefit from fast response time and compactness features; however, due to the lack of zero current realization and high-power losses, the reliability and efficiency of these devices is low. The system proposes a solid-state DC breaker for medium voltage DC (MVDC) systems. The presented structure have two main parts: 1) a main conduction branch including stacked MV Silicon-Carbide (SiC) devices to improve the efficiency and provide a fast response time, 2) a breaker branch including a wireless capacitive coupling to avoid metal-to-metal contact and increase the overall reliability, and also a modular current pulse power supply to realize zero-current switching.