baber/WOPTO huggingface dataset:
Patent AT-E184323-T1 (AT)
Inventor: CARDY DONALD LEONARD NICHOLAS
IPC: G01N33/53
Filed: 1992-07-06
Granted: 1999-09-15
Abstract: Disclosed is a homogeneous assay method for determining the presence of a nucleic acid sequence of interest in a sample, comprising combining in solution: the sample; a first nucleic acid probe substantially complementary or homologous to at least part of the sequence of interest and associated, or capable of being associated, with an enzyme or a substance capable of affecting the activity of an enzyme; a second probe capable of binding to the first probe or capable of binding to at least part of the sequence of interest and comprising a ligand moiety; and a binding partner capable of binding to said ligand moiety, the arrangement being such that when the first and second probes are bound in proximity an effect of the binding partner on enzyme behaviour is altered; and monitoring said enzyme behaviour.
Patent AT-E232730-T1 (AT)
Inventor: GOOD A HEATHER
IPC: A61K35/12
Filed: 1992-08-21
Granted: 2003-03-15
Abstract: Antibody-mediated xenograft rejection is attenuated by (1) removing preformed antibodies to various identified carbohydrate xenoantigens from the recipient's circulation prior to transplantation by extracorporeal perfusion of the recipient's blood over a biocompatible solid support to which the xenoantigens are bound and/or (2) parenterally administering a xenoantibody-inhibiting amount of an identified xenoantigen to the recipient shortly before graft revascularization and thereafter.
Patent AT-E149155-T1 (AT)
Inventor: MURUGESAN NATESAN
IPC: A61K31/42
Filed: 1993-04-29
Granted: 1997-03-15
Abstract: Compounds of the formula <CHEM> inhibit the activity of endothelin. The symbols are defined as follows:     one of X and Y is N and the other is O;     R<1>, R<2> and R<3> are each independently <a)   hydrogen, except that R<1> is other than hydrogen; <b)   alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloalkenylalkyl, aryl, aryloxy, aralkyl, or aralkoxy, any of which may be substituted with Z<1>, Z<2> and Z<3>; <c)   halo; <d) hydroxyl; <e)   cyano; <f)   nitro; <g)   -C(O)H or -C(O)R<6>; <h) -CO2H or -CO2R<6>; <i)   -SH, -S(O)nR<6>, -S(O)m-OH, -S(O)m-OR<6>, -O-S(O)m-R<6>, -O-S(O)mOH, or -O-S(O)m-OR<6>; <j)   -Z<4>-NR<7>R<8>; or <k)   -Z<4>-N(R<1><1>)-Z<5>-NR<9>R<1><0>; and the remaining symbols are as defined in the specification.
Patent AT-E171074-T1 (AT)
Inventor: BURNOUF MIRYANA NEE RADOSEVICH
IPC: A61K35/16
Filed: 1993-02-04
Granted: 1998-10-15
Abstract: The invention relates to a composition intended to stabilise blood plasma during pasteurisation, the blood plasma being whole or devoid of cryoproteins. The composition according to the invention makes it possible to pasteurise very large quantities of plasma (of the order of 60 litres). The invention also relates to the method for pasteurisation of the plasma using the stabilising composition. The pasteurised plasma obtained is intended for therapeutic use.
Patent AT-E152143-T1 (AT)
Inventor: MELDAL MORTEN PETER
IPC: C07K1/113
Filed: 1993-02-12
Granted: 1997-05-15
Abstract: A crosslinked poly(ethylene or propylene)glycol-containing polymer which has a unique spatial structure and can be designed especially for application as a chromatographic resin or as a solid support for the synthesis of peptides, oligonucleotides or oligosaccharides or as a substrate for the immobilization of proteins. The polymer is formed by radical copolymerization of derivatized poly(ethylene or propylene) glycol bis-end substituted with a moiety selected from the group consisting of acryloylalkyl, acryloylaryl, acrylamidoalkyl and acrylamidoaryl with an acrylic amide, nitrile or ester. When it is to be used as a solid support or immobilization substrate, the polymer will incorporate a spacer comprising functional groups for the attachment of peptides, proteins, nucleotides or saccharides such as those selected from the group consisting of amino, alkylamino, hydroxy, carboxyl, mercapto, sulfeno, sulfino, sulfo and derivatives thereof.
Patent AT-E167796-T1 (AT)
Inventor: TRAWOEGER WERNER
IPC: A61G15/14
Filed: 1993-03-15
Granted: 1998-07-15
Abstract: In order to form a rotating connection between a dental suction tube and a connector block (10, 11) on a tube-support unit, the pipe elbow proposed has two lengths of pipe (1, 2) disposed at an angle to each other and an externally located support pin (9) lying in the axis of rotation (8) of the first length of pipe (1).
Patent AT-E151614-T1 (AT)
Inventor: PEDERSEN KNUD GROENLUND
IPC: A61B5/145
Filed: 1993-07-12
Granted: 1997-05-15
Abstract: The sensor (1) comprises a sensor body (3) thermostatable by means of a first thermostating system (14,15) and having an outer surface (3a,40a) for application to the human body (28) in heat conductive relationship therewith, said outer surface (3a,40a) forming the measuring surface of the sensor (1). The sensor (1) further comprises analyte sensing means (7,8) arranged in said sensor body (3) and being thermostated through said body (3) by means of the first thermostating system (14,15). The sensor (1) further comprises means (16,41) arranged in the sensor body (3) in heat insulated relationship therewith while in heat conductive relationship with a delimited surface part of the sensor measuring surface (3a,40a). The means (16,41) is thermostatable by means of a second thermostating system. The delimited surface part is located within the outer periphery of the sensor measuring surface (3a,40a).
Patent AT-E165676-T1 (AT)
Inventor: BREUER NORBERT DR
IPC: G04B37/14
Filed: 1994-02-04
Granted: 1998-05-15
Abstract: Wristwatch with a watch housing (1) with end pieces (3, 15, 16) projecting from the edge of the watch housing (1), which, for fastening a wrist strap (2), secure two webs (7) at their ends at a distance from the edge of the watch housing (1). The respective web (7) is mounted pivotably with one end in one of the end pieces (3; 15) and rests with its other end detachably, but in a secured manner, in a recess (9) of an end piece (3; 16) lying opposite its pivot bearing (10, 11). <IMAGE>
Patent AT-E166449-T1 (AT)
Inventor: MARUYAMA NOBORU
IPC: F28D1/06
Filed: 1994-02-08
Granted: 1998-06-15
Abstract: The heat absorbing member formed by connecting to the bottom portion of the inlet header (1) with that of the outlet header (2) through the heat absorbing tube is installed so that the heat absorbing tube is located in the heating container (9), the heat absorbing tube (16) is comprised of a plurality of the down tubes (3, 4) and down tubes (5, 6) all with lower ends closed and connected under the inlet header (1) and outlet header (2) respectively, and the spiral tubes (7, 8) which connect to the top with the bottom portion of the down tubes (3, 4) and down tubes (5, 6), and the spiral tubes (7, 8) are the same length. <IMAGE>
Patent AT-E168022-T1 (AT)
Inventor: EICK RUEDIGER
IPC: A61M39/00
Filed: 1994-05-26
Granted: 1998-07-15
Abstract: The invention specifies a tube connector for connection of tubing lines for medical purposes, comprising a first coupling member (3) with an internal cone (24) and outside projections (25) lying diametrically opposite and representing a fragment of a double external screw thread, and a second coupling member (2) with an external cone (9) and a freely rotatable connection member (4) whose tube socket (28), which is open in the direction of the first coupling member (3), has an internal screw thread (26) for reception of the external screw thread formed by the projections, and having a rotation-preventing mechanism. The latter is formed by locking strips (27) which are arranged diametrically opposite in the central region of the first coupling member (3), project radially and whose functional surfaces interact with engagement projections (29) or their functional surfaces (30, 31) arranged diametrically opposite on the inner casing of the elastically deformable tube socket (28). <IMAGE>
Patent AT-E177803-T1 (AT)
Inventor: KORHONEN VILLE
IPC: D21G1/00
Filed: 1994-12-09
Granted: 1999-04-15
Abstract: The invention concerns a calender, comprising a calender frame (11,12) and a stack of rolls mounted on the frame and consisting of four rolls (13,14,15, 16) fitted one above the other, in which stack the rolls placed one above the other can be fitted in nip contact with one another so as to calender the paper web (W) or equivalent in said nips (N1,N2,N3,). The stack of rolls in the calender is composed of three variable-crown rolls (13,14,16), of which rolls the roll mantle (17) of at least one roll (13) can be displaced in relation to the roll axle (18) in the direction of the nip plane by means of loading devices (19) fitted inside said roll, as well as of one heatable roll (15), which is fitted between two variable-crown rolls (14,16) in the stack of rolls. The roll is preferably arranged so that, in the stack of rolls, the lowest, i.e. the first roll (13), the second roll (14), and the topmost, i.e. the fourth roll (16) are variable-crown rolls and that the third roll (15) in the stack of rolls is a heatable roll. <IMAGE>
Patent AT-E160794-T1 (AT)
Inventor: SMEAL THOMAS W
IPC: C08F290/06
Filed: 1994-03-14
Granted: 1997-12-15
Abstract: A laminating resin comprising (A) an acrylated or methacrylated cycloaliphatic epoxide, (B) an acrylated or methacrylated alkoxylated bisphenol-A, in a weight ratio of (A) to (B) of about 3 to 1 to about 1 to 5, and (C) about 5% to about 50%, based on the total composition, cyclohexyl methacrylate. Vinyl toluene and ethylene glycol dimethacrylate are also used to modify certain properties of the resin.
Patent AT-E215559-T1 (AT)
Inventor: HOUGHTEN RICHARD A
IPC: C07K1/04
Filed: 1994-06-10
Granted: 2002-04-15
Abstract: Linear C1-C7-alkyl peralkylated oligopeptide sets of molecules are specific peralkylated oligopeptides, disclosed, as are their methods of synthesis and use in acceptor binding assays. Each molecule or chain of a set contains the same number of two to about ten substituted C1-C7-alkyl peralkylated amino acid residues, and the member chains of a set are present in equimolar amounts. The chains of a set contain one or more predetermined peralkylated amino acid residues at one or more predetermined positions of the peralkylated oligopeptide chain. The set contains equimolar amounts of at least six different peralkylated amino acid residues at one or more of the same predetermined positions of the peralkylated oligopeptide chain. Libraries of such sets, processes for their use and solid support-linked peralkylated sets are also contemplated, as are specific permethylated oligopeptides such as those having 5-8 phenylalanine residues that have antimicrobial properties.
Patent AT-E167613-T1 (AT)
Inventor: ULLMANN ROLAND
IPC: B65D25/10
Filed: 1994-10-29
Granted: 1998-07-15
Abstract: The invention is directed to a case for storing small appliances for personal use. The case (2) is comprised of a supporting structure (4) having at least two sections (8, 10) jointed to each other by a deflecting means (6). Provided on either section (8, 10) is at least one retaining means (12, 14) receiving an appliance and an accessory. Related to the deflecting means, the retaining means (12, 14) are so arranged that they lie side-by-side in a row when the sections (8, 10) are folded one over the other.
Patent AT-E183630-T1 (AT)
Inventor: MOSIMANN VINCENT
IPC: A61C1/00
Filed: 1995-05-15
Granted: 1999-09-15
Abstract: The accessory e.g. lamp for illumination of the hand-held instrument (L) and the excitation coils (B1-B3) of the brushless motor (M) are all supplied with current through a rotary connector (F) from a control circuit (C1) within a fixed part of the machine or power cable. Positive and negative supply lines (L1, L2) from a voltage source (S) feed three pairs of controlled transistor switches (CE1-CE3) whose midpoints (P1-P3) are wired to terminals (b1-b3) of the star-connected coils. The lamp is fed from a separate controlled switch (T4) wired to one (N1) of its terminals; the other (N2) is returned to the free terminal (b3) of one coil. <IMAGE>
Patent AT-E189148-T1 (AT)
Inventor: DAVID DAVID ALBERT
IPC: B23K9/133
Filed: 1995-08-04
Granted: 2000-02-15
Abstract: A torch wire feeder which includes a planetary feeder, an electrical motor and a handle. The feeder is characterized in that the electrical motor (2) along with the planetary head (1) is mounted to a back holder (3), and the goose-neck (15) is mounted to a front holder (13), as the front (13) and the back holders (3) are assembled with the tubes (4,5,6) for water-cooled and gas-cooled operation, as the back holder (3) receives the wire from the conduit (8) with holder thread nut (7). Furthermore, water tubes (18,21) and a gas tube (19) from the conduit (9) are assembled to the back holder (3) with a nut, and the front holder has distributor holes (25,22,23) for gas and water cooling and also thread nut (14) for transmitting the welding current, the water and the gas from the conduit to the neck (15), also contacting the holder (13) to the thread nut (14) with rubber seal (27), as all the parts are assembled to the handle (12) with ergonomic form and also containing two potentiometers (28,29) and start-stop switch (11) and the hook (30), a all details and parts are included in ergonomic form body (12). <IMAGE>
Patent AT-E199471-T1 (AT)
Inventor: VAN DER LELY ARY
IPC: A01C15/00
Filed: 1984-05-30
Granted: 2001-03-15
Abstract: An agricultural spreader comprises distribution members (11, 12) which rotate to eject material such as fertilizer. The spreader can tilt to one side or the other so as to reduce the spreading distance on one side. This facility enables the spreader to be driven on a field along the same tracks as other agricultural machinery while avoiding waste of material at the edges of fields. Other embodiments utilize braking members which are movable into the path of ejected material to reduce its kinetic energy and consequently its spreading distance.
Patent AT-E177123-T1 (AT)
Inventor: LE-KHAC BI
IPC: C08K3/28
Filed: 1995-08-29
Granted: 1999-03-15
Abstract: A solid double metal cyanide (DMC) catalyst useful for epoxide polymerisation comprises: (a) a double metal cyanide cpd; (b) an organic complexing agent; and (c) about 5-80 wt% based on the amt of catalyst, of a polyether having a number average molecular wt greater than about 500. Also claimed are: Preparing a solid DMC catalyst in the presence of an organic complexing agent and a polyether as above, wherein the solid DMC catalyst contains 5-80 wt% of the polyether. Preparing a soli DMC catalyst useful for epoxide polymerisation.
Patent AT-E212208-T1 (AT)
Inventor: BAROUK LOUIS SAMUEL
IPC: A61B17/86
Filed: 1995-07-05
Granted: 2002-02-15
Abstract: The screw consists of threaded proximal and distal sections, with the proximal section having a diameter greater than that of the distal section and a thread of smaller pitch. The distal section is threaded to practically the whole of its length, and the upper surfaces (11,21) of the threads on both sections lie perpendicular to the axis of the screw, while their lower surfaces (12,22) are oblique. Each thread section also has a notch (13,23), and the screw has an axial channel (4) to allow a guide rod to be used with it. The screw can be made, for example, from a biocompatible metal such as titanium of TA 6 V, a chrome-cobalt alloy or stainless steel, or from a bio-integrable material such as calcium phosphate or hydroxyapatite.
Patent AT-E170959-T1 (AT)
Inventor: ROELLIN ULRICH
IPC: F16B5/02
Filed: 1995-02-17
Granted: 1998-09-15
Abstract: The corner connection comprises an angle piece with clamp screws such that they are attached too clamp plates which are guided into a groove running along the metal profiles . Thrust bearing surfaces (23) are positioned along the arms (18) of the angle bracket (12) and point towards profiled flaps (14). Lengthwise grooves (15) are positioned in the profiled flaps near the join between the profiled flaps and flanges (16). The grooves are as deep as, or deeper than, the height of the thrust pieces fitting into the grooves. The profiled flaps have a top surface at right angles to the sides and to the flange. The cross section of the profiled flaps tapers in a wedge shape towards the side walls. The clamping plates have wedge shaped friction surfaces congruent with the wedge shaped contact surfaces of the profiled flaps.
Patent AT-E170507-T1 (AT)
Inventor: TOOZE ROBERT PAUL
IPC: B01J31/24
Filed: 1994-12-06
Granted: 1998-09-15
Abstract: A process capable of the low temperature carbonylation of an acetylenically unsaturated compound with carbon monoxide in the presence of an allenically unsaturated compound using a catalytic system, which is at least tolerant of the allenically unsaturated compound, formed from a) a palladium compound; b) a protonic acid; c) an organic phosphine of form (I), wherein R<1> is an optionally substituted aryl group; R<2> and R<3> are joined to form an optionally substituted cyclic moiety comprising at least one optionally substituted alkylene group.
Patent AT-E236679-T1 (AT)
Inventor: RUSSO RONALD D
IPC: A61M25/00
Filed: 1994-12-07
Granted: 2003-04-15
Abstract: Retention bolsters for a percutaneous catheter which have a convexly curved exterior surface which contacts the epidermal surface of a patient, and which also provide protection against the catheter kinking. The retention bolsters slide over a catheter until contacting the skin of the patient at the catheter exit site. When secured in place, the bolsters rock along contacting portions between their convexly curved surface and the epidermal surface of the patient in response to movement of the catheter about the exit site, thereby alleviating the added pressure that would otherwise be applied by this movement. Upon the release of lateral pressure against the catheter device, the bolsters return to their original upright position. One bolster incorporates an elongated collar which is flexibly resilient to supportively allow the catheter to be laterally bent away from the exit site without kinking. A removable twist lock is placed around the collar portion of the bolster to securely lock the bolster to the catheter and can also be easily disengaged if the user desires to adjust the bolster or temporarily loosen it so that the surface underneath the bolster can be cleaned. A second bolster prevents kinking of the bolster by means of a curved passageway therein which orients the catheter toward a side exit which is substantially parallel to the skin surface. The side exit bolster also facilitates attachment by means of a slit therein which allows the bolster to be easily advanced over the catheter and pivoted into position thereon.
Patent AT-E215492-T1 (AT)
Inventor: HARRIS RANDALL L
IPC: B65D71/12
Filed: 1994-12-19
Granted: 2002-04-15
Abstract: A wrap-around carrier containing means for covering the pricing code on the end articles in the package. Straps connected to the side panels extend between the end articles and the side panels and across the end of the carrier to both conceal the article price code and to act as a restraint against outward movement of the articles. The straps are formed from cutouts in the top and side panels of the carrier, leaving a handle strip in the top panel.
Patent AT-E205079-T1 (AT)
Inventor: YEN SHAU-FONG
IPC: A61K9/08
Filed: 1995-02-09
Granted: 2001-09-15
Abstract: Disclosed is a sustained release liquid aqueous ophthalmic delivery system and a method of providing a slow and sustained release of ophthalmic treating agents to the eye of a mammal which comprises administering to the eye of a said mammal an effective amount of a homogeneous liquid aqueous ophthalmic pharmaceutical composition, of pH between about 3.0 and about 6.2, which is adminstrable in drop form and which comprises an ophthalmically effective concentration of a said ophthalmic treating agent and about 0.05% to about 10% by weight of the polymer chitosan; said polymer consisting essentially of (A) monomeric  beta (1->4)-D-glucosamine linked units and of (B) monomeric  beta (1->4)-D-glucosamine linked units which are scattered randomly in the molecule of the polymer, the numerical proportions of A and B being from about 60 to about 99% of A and about 1 to about 40% of B, the viscosity rating being from about 3 to about 3000 cps; in which method, upon contact with the higher pH of the ocular fluid, said liquid formulation is converted to a stiff gel from which the ophthalmic treating agent is slowly released over a prolonged period of time.
Patent AT-E224908-T1 (AT)
Inventor: COOK PHILLIP DAN
IPC: C12N9/99
Filed: 1995-02-23
Granted: 2002-10-15
Abstract: Compounds are provided having the structure:   <IMAGE>   wherein the L groups are spanner or linker units, the Y and T group are functional groups for interacting with target molecules of interest, the X groups are oxygen or sulfur and the E groups are H, conjugate groups or intermediate groups used during the synthesis of the compounds are prepared using H phosphonate type chemistry wherein the functional groups are added during an oxidization step.
Patent AT-E201866-T1 (AT)
Inventor: HARRISON TIMOTHY
IPC: A61K31/5375
Filed: 1995-08-07
Granted: 2001-06-15
Abstract: PCT No. PCT/GB95/01868 Sec. 371 Date Feb. 13, 1997 Sec. 102(e) Date Feb. 13, 1997 PCT Filed Aug. 7, 1995 PCT Pub. No. WO96/05181 PCT Pub. Date Feb. 22, 1996The present invention relates to compounds of formula (I)    <IMAGE>  (I)  wherein X is -NR6R7 or C- or N-linked imidazolyl; Y is hydrogen or C1-4alkyl optionally substituted by hydroxy; R1, R2, R3, R4 and R5 are selected from a variety of suitable aromatic substituents; R6 is hydrogen, C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkylC1-4alkyl, phenyl, or C2-4alkyl substituted by C1-4alkoxy or hydroxy; R7 is hydrogen, C1-6alkyl, C3-7cycloalkyl, C3-7cycloalkyl C1-4alkyl, phenyl, or C2-4alkyl substituted by one or two of C1-4alkoxy, hydroxy or a 4, 5 or 6 membered heteroaliphatic ring containing one or two heteroatoms selected from N, O and S; or NR6R7 is a saturated or partially saturated heterocyclic ring of 4 to 7 ring atoms, optionally containing one of O, S, NR8, S(O) or S(O)2 and optionally substituted by one or two of hydroxy1-4alkyl, C1-4alkoxy C1-4alkyl, oxo, CORa or CO2Ra; or NR6R7 forms a non-aromatic azabicyclic ring system of 6 to 12 ring atoms; and R9a and R9b are each independently hydrogen or C1-4alkyl, or R9a and R9b are joined so, together with the carbon atoms to which they are attached, there is formed a C5-7ring; or a pharmaceutically acceptable salt thereof. The compounds are of particular use in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.
Patent AT-E192152-T1 (AT)
Inventor: CARCELLER ELENA
IPC: A61K31/445
Filed: 1995-09-05
Granted: 2000-05-15
Abstract: PCT No. PCT/EP95/03487 Sec. 371 Date Oct. 22, 1996 Sec. 102(e) Date Oct. 22, 1996 PCT Filed Sep. 5, 1995 PCT Pub. No. WO96/14317 PCT Pub. Date May 17, 1996   <IMAGE>  I  Compounds of general formula I and their salts and solvates are PAF antagonists and as such are useful in the treatment of various diseases or disorders mediated by PAF. Pharmaceutical compositions including these compounds and processes for their preparation are also provided.
Patent AT-E191477-T1 (AT)
Inventor: SAKAMOTO NORIYASU
IPC: C07D213/64
Filed: 1995-10-12
Granted: 2000-04-15
Abstract: The dihalopropene compounds of the general formula (I) have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks.