baber/WOPTO huggingface dataset:
Patent CO-6260156-A2 (CO)
Title: Cebadores y sendas para la detecciondel estado de metilacion de un gen, incluyendo el gen mage-a3
Inventor: VLASSENBROECK ILSE
IPC: A61K38/08
Filed: 2010-03-19
Abstract: Un oligonucleótido, cebador o sonda comprende la secuencia de nucleótidos de cualquiera de las SEQ ID Nos: 5, 6, 7, 2, 3, 4, 8, 9, 11, 12, 13, 14, 15, 16, 17, 18, 19 ó 25. Los oligonucleótidos son útiles para la detección del estado de metilación de un gen, en particular del gen MAGE-A3. Los oligonucleótidos son útiles en pares de cebadores, kits, y métodos para determinar el estado de metilación del gen MAGE-A3, y para diagnosticar el cáncer, para dirigir la terapia, y para seleccionar a los sujetos para el tratamiento. El cebador o la sonda puede comprender una estructura de ciclo o de horquilla, y se puede utilizar en la reacción en cadena de la polimerasa (PCR) específica de la metilación en tiempo real. 1.- Un oligonucleótido, cebador o sonda que comprende, o que consiste esencialmente en, o que consiste en la secuencia de nucleótidos de cualquiera de las SEQ ID NOs: 5, 6, 7, 2, 3, 4, 8, 9, 11, 12, 13, 14, 15, 16, 17, 18, 19 ó 25, cuyo oligonucleótido, cebador o sonda es útil para la detección del estado de metilación de un gen. 2.- Un oligonucleótido, cebador o sonda de acuerdo con la reivindicación 1, que comprende, que consiste esencialmente en, o que consiste en la secuencia de nucleótidos de cualquiera de las SEQ ID NOs: 5, 6, 7, 2, 3, 4 ó 25, cuyo oligonucleótido, cebador o sonda es útil para la detección del estado de metilación de un gen.
Patent CO-6270336-A2 (CO)
Title: Composiciones pepticidas que comprenden uno o mas polipetidos
Inventor: STOLOFF GREGORY ALAN
IPC: A61K38/01
Filed: 2010-04-13
Abstract: Se proporciona una composicion polipeptidica que comprende uno o mas polipéptidos, polipéptidos los cuales son inmunogénicos en un vertebrado de modo que hace que el vertebrado produzca células del sistema inmune capaces de reconocer al menos un epitope de una fraccion de proteina de saliva de artropodo, donde la fraccion de proteina de saliva tiene una masa de 40kDA o menos, y donde los polipéptidos son seleccionados independientemente de: las secuencias polipeptidicas de SEQ ID 1-44 o subsecuencias de esas secuencias, las subsecuencias tienen 7 aminoacidos o mas; o de las secuencias polipeptidicas que tienen una homologia del 85% o mas con una o mas de las secuencias anteriores y contenidas en una o mas de las siguientes bases de datos: GenBank, Protein Data Bank (PDB), SwissProt, Protein Information Resource (PIR), protein Research Foundation (PRF) , o traducciones de CDS de esas.
Patent CO-6300927-A2 (CO)
Title: Sales de arginina y un cation, productos de cuidado oral y personal que los contienen y metodos para preparar dichas sales y productos
Inventor: PRENCIPE MICHAEL
IPC: A61K8/44
Filed: 2010-09-02
Abstract: 1.- Una sal de arginina y uno o más de los siguientes ácidos conjugados: a. un polímero ácido; b. un ácido conjugado de una sal tensioactiva aniónica; c. un ácido polifosfórico o polifosfónico, o d. un agente antimicrobiano ácido.2.- La sal de la reivindicación 1 en forma sólida.3.- La sal de la reivindicación 1, en la que el ácido conjugado es un polímero ácido.4.- La sal de la reivindicación 1, en la que el ácido conjugado es el ácido conjugado de una sal tensioactiva aniónica.5.- La sal de la reivindicación 1, en la que el ácido conjugado es un ácido polifosfórico.6.- La sal de la reivindicación 1, en la que el ácido conjugado es un ácido polifosfónico.7.- La sal de la reivindicación 1, en la que el ácido conjugado es un agente antimicrobiano ácido.8.- La sal de la reivindicación 3, en la que el polímero ácido es un polímero policarboxilato.
Patent CO-6351834-A2 (CO)
Title: Disyuntor con funcion auto-trabadora en cortocircuito
Inventor: WAN JIASHENG
IPC: H01H71/10
Filed: 2011-02-03
Abstract: El objeto de la presente invención es suministrar un mecanismo auto-trabador en cortocircuito, provisto en un disyuntor de circuitos. El mecanismo auto-trabador en cortocircuito de la presente invención comprende un mecanismo auto-trabador y un mecanismo de restablecimiento. El mecanismo auto-trabador en cortocircuito comprende un mecanismo auto-trabador que opera para mantener un varillaje disparador, en un estado de protección contra un cortocircuito, y el mecanismo de establecimiento opera para forzar al varillaje disparador a restablecer su estado inicial. El disyuntor de la presente invención no puede ser cerrado directamente cuando el disyuntor está desconectado, de manera que indique el incidente de cortocircuito a los operadores y el disyuntor debe ser cerrado de nuevo después que se identifique y se resuelva el problema.
Patent CO-6531438-A2 (CO)
Title: Perforación giratoria mejorada por resonancia
Inventor: WIERCIGROCH MARIAN
IPC: E21B7/24
Filed: 2012-04-12
Abstract: Un método para controlar una perforación giratoria mejorada por resonancia, que comprende una barrena perforadora giratoria y un oscilador para aplicar carga oscilatoria axial a la barrena perforadora giratoria, comprendiendo el método: controlar la frecuencia (f) del oscilador en la perforación giratoria mejorada por resonancia, por lo que la frecuencia (f) se mantiene en el rango (D2 Us/8000(Am))1/2 = f = Sf(D2 Us/(8000(Am))1/2, en el que D es el diámetro de la barrena perforadora giratoria, Us es la resistencia a compresión del material que se está perforando, A es la amplitud de la vibración, m es la masa vibratoria, y Sf es un factor de escala mayor que 1; y controlar la fuerza dinámica (Fd) del oscilador en la perforación giratoria mejorada por resonancia, por lo que la fuerza dinámica (Fd) se mantiene en el rango [((/4) D2effUs] = Fd = SFd[((/4) D2effUs], en el que Deff es un diámetro efectivo de la barrena perforadora giratoria, Us es una resistencia a compresión del material que se está perforando, y SFd es un factor de escala mayor que 1, en el que la frecuencia (f) y la fuerza dinámica (Fd) del oscilador son controladas supervisando señales que representan la resistencia compresiva (Us) del material que se está perforando y ajustando la frecuencia (f) y la fuerza dinámica (Fd) del oscilador utilizando un mecanismo de realimentación en tiempo real de circuito cerrado de acuerdo con cambios en la resistencia a compresión (Us) del material que se está perforando.
Patent CO-6541547-A2 (CO)
Title: Derivados de sulfonamida heterocíclicos útiles como inhibidores de mek
Inventor: BOCK MARK G
IPC: A61K31/4355
Filed: 2012-05-04
Abstract: La presente invención se refiere a los compuestos de la fórmula (lA):en donde R1a, R1b, X, R2a, R2b, W, R3, R4, y R5 son como se definen en la presente, así como a las sales farmacéuticamente aceptables de los mismos. Se ha demostrado que los compuestos actúan como inhibidores de MEK, lo cual puede ser útil en el tratamiento de enfermedades hiperproliferativas, como cáncer e inflamación.
Patent CO-6551749-A2 (CO)
Title: Dispositivo y método para la aplicción tópica de composiciones terapéuticas o cosméticas
Inventor: RUEGG L CURTIS
IPC: A61M35/00
Filed: 2012-05-30
Abstract: La presente invención se refiere a dispositivos y métodos para reconstituir y administrar de forma segura composiciones tópicas terapéuticas o cosméticas. El aplicador tópico de acuerdo con la invención es particularmente adecuado para guardar, reconstituir y administrar o aplicar sustancias altamente tóxicas.
Patent CO-6630092-A2 (CO)
Title: Sistema de desenrollado de metal en laminas verticales
Inventor: ANDERSON TODD E
IPC: B65H16/00
Filed: 2012-09-21
Abstract: Un dispositivo para desenrollar una bobina del material en láminas incluye una estructura de soporte, un eje susceptible de rotarse soportado por la estructura de soporte, y múltiples rodillos de soporte cónicos soportados por la estructura de soporte. El eje susceptible de rotarse tiene un eje de rotación que se orienta en una orientación vertical y está configurado para ubicarse en un núcleo hueco de una bobina del material en láminas. Los múltiples rodillos de soporte cónicos están configurados para soportar a base de la bobina del material en láminas, cada rodillo de soporte cónico tiene una forma cónica con un extremo ancho y extremo estrecho. Cada rodillo de soporte cónico tiene un eje de rotación y está dispuesto de manera tal que su respectivo eje de rotación está orientado hacia el eje de rotación del eje susceptible de rotarse. Cada rodillo de soporte cónico está dispuesto de manera tal que un extremo estrecho del rodillo de soporte cónico está ubicado hacia el eje susceptible de rotarse.
Patent CO-7230333-A2 (CO)
Title: Dispositivo para tratar un líquido
Inventor: REEDTZ TOR
IPC: A23L19/00
Filed: 2014-12-23
Abstract: VER ANEXOS
Patent EP-1050493-A2 (EP)
Inventor: SCHOETTLER LUDGER
IPC: B65G17/12
Filed: 2000-01-07
Abstract: A lifting conveyer receives items surrendered from a horizontal conveyer, and raises these vertically to a higher plane for surrender to another station. The lifting conveyer has a frame (1) and guides (3), a primary drive (9,10,15) acting on a carriag (4) moving along a track (11,12). The carriage holds the load carrier (6). The carriage is linked to the drive (9) by a couple (20,21). The guides are slab-shaped with narrow sides. The carriage moves on rollers (5) against the guide edges.
Patent EP-1087127-A2 (EP)
Inventor: TAKATA HIROSHI
IPC: F02B61/02
Filed: 2000-01-31
Abstract: An intake apparatus is provided for an engine of a vehicle. The intake
apparatus can introduce fresh air under the vehicle's large running wind pressure.
The intake apparatus also allows the opening area and profile of an air inlet to be
selected freely. The intake apparatus includes a pair of intake ducts 13 for
introducing the air into the engine and an air-introducing duct 15 connected to
respective upstream ends of the intake ducts 13 to provide the air inlet 14. The
air-introducing duct 15 is formed independently of a cowling 16 fitted to a front
of the vehicle. The air-introducing duct 15 has its leading end 15a positioned
ahead of a leading end 16a of the cowling 16.
Patent EP-1034964-A2 (EP)
Inventor: ZEISS MANFRED
IPC: B60R11/02
Filed: 2000-02-17
Abstract: The frame (2) has a surround (7) which is provided with a decorative panel (3) provided with cut-outs for instruments (4). The panel is secured in an undercut (8) in the surround. The front frame can be an injection moulding with the decorative panel placed in the injection mould to ensure an invisible bond
Patent EP-1030417-A2 (EP)
Inventor: INOUE TADAO
IPC: H01S5/00
Filed: 2000-02-18
Abstract: Using a switching signal from a coarse/fine
switching and operation mode switching circuit (26), the width
of change of a counter control value during power up is
increased, and the width of change is reduced once a
steady state is reached. In the steady state, the
frequency of updating is limited by a control signal from
an update permit control circuit. In the steady state,
the frequency band of a current source in an LD driving
circuit (10) is reduced in width.
Patent EP-1033762-A2 (EP)
Inventor: BAUMGAERTNER MANFRED DR
IPC: H01L31/0352
Filed: 2000-03-06
Abstract: A solar collector, comprising hollow or porous fibers internally coated or impregnated with photovoltaic active material, is new. Preferred Features: The hollow fibers are coated with doped semiconductors forming transparent electrode and counter-electrode contact layers separated by an absorption layer. The porous fibers are impregnated successively with several active material layers forming one or more p-n junctions.
Patent EP-1037492-A2 (EP)
Inventor: SATO KOUKI
IPC: H04Q11/00
Filed: 2000-03-15
Abstract: An approach for performing fault recovery in an optical
communications network is disclosed. An optical switch is
connected to working optical fibers and protection optical
fibers, which carry WDM (wave division multiplexing) optical
signals. The optical switches possess functionality to
switch over the optical signals among the working optical
fibers and the protection optical fibers. The optical switch
includes dual unit optical switches that have a common
driving mechanism. The common driving mechanism is
configured to perform simultaneously switching operation of
the unit optical switches to alter a switching state of the
optical switch. Monitoring devices are distributed
throughout the node to monitor the transmitted optical
signals over the optical fibers, and to output monitoring
signals that indicate one or more faults in these optical
fibers. In response to the monitoring signals, a control
device outputs control signals to the optical switches to
effect an optical protection scheme.
Patent EP-1095737-A2 (EP)
Inventor: BRANDSTETTER JOSEF
IPC: B24D9/08
Filed: 2000-03-24
Abstract: The rear side of the flange (7) has two concentric ring supporting surfaces (8,9) on the inside and outside rims of the flange rear side. The surfaces project beyond the flange rear to serve as mounting for the disk (6) placed on the nearest lamellar grinding wheel (2). The inner ring surface (8) is formed by a rising transition area from the flange rear face to the wheel boss (3) as against the outer (9) which consists of a bead or shoulder on the outside rim of the flange rear. The transition area can form a hollow throat or a smooth ramp and the rear face of the flange should be capable of taking print (17) between the ring surfaces (8,9).
Patent EP-1065356-A2 (EP)
Inventor: YOSHIKATSU IIDA
IPC: F01M13/00
Filed: 2000-05-24
Abstract: A four-stroke cycle engine having an intake passage and an exhaust passage both
opening to a combustion chamber, and having an intake valve for opening and closing
the intake passage and an exhaust valve for opening and closing the exhaust passage,
with blowby leaking from the combustion chamber into a crank chamber returned to the
intake passage through a circulation passage and with the circulation passage. A fresh
air intake passage is provided to make fluid communication between part of the intake
passage on the upstream side of a throttle valve and the crank chamber, with the fresh
air intake passage provided with a fresh air inflow valve.
Patent EP-1093763-A2 (EP)
Inventor: SCHAEFER BERND
IPC: A61B17/70
Filed: 2000-06-24
Abstract: The bone-plate (10) has a plate-shaped basic body (12) and a cover (14). The basic body has an opening into which a bone-screw is screwed. The screw-head is contained by the screw-opening. The basic body has a holder -part (24) for a fixture-bar and symmetrically containing the opening.
Patent EP-1075904-A2 (EP)
Inventor: SELLA GIOVANNI
IPC: B25B11/00
Filed: 2000-08-02
Abstract: This invention refers to a fastening unit for blocking the items to be processed on the
working plane of a tooling machine of a type comprising a mobile support along a guide
equipped with devices for blocking the item, characterized in that it provides for at least
one device for blocking the item to be processed, constituted by a pressing element which
is mobile between a raised position allowing the introduction of the item and a lowered
position in which it blocks the item against its support.
Patent EP-1093957-A2 (EP)
Inventor: WINAND HELMUT DIPL-ING
IPC: B60L3/00
Filed: 2000-09-12
Abstract: The method involves using a voltage measuring device connected between the earthed pole of the tram overhead line and the chassis. The measured voltage and its time are compared with known voltage-time curves, for a high voltage dropping quickly and a low voltage dropping slowly. If the measured voltage is bigger than the corresponding value on one of the curves, an alarm signal or switch is released. Independent claims are included for a unit for implementing the method and for a method for testing the unit.
Patent EP-1096277-A2 (EP)
Inventor: HUANG AUSTIN LANCELOT
IPC: G02B5/30
Filed: 2000-10-26
Abstract: A polarizer (300) is made from pairs of polarizing beam splitting cubes (302, 352).
In every pair, a first cube (302) transmits P-polarized light and reflects S-polarized light. A
retarder (330) rotates the transmitted light to become S-polarized. A second cube (352)
receives only the reflected light, and redirects it in the direction of the transmitted light. A
polarizing filter (370) filters the reflected light, but not the rotated light. Exposing the
retarder (330) improves the transmission throughput of the overall polarizer (300). A stop at
the side of the second cube (352) blocks light from entering the first cube (302) of an
adjacent pair.
Patent EP-1096469-A2 (EP)
Inventor: MATSUO KENJI
IPC: H01L41/083
Filed: 2000-10-27
Abstract: An ultrasonic vibration apparatus includes a casing (2)
having a vibration face, a piezoelectric element (1) mounted
in the casing (2), and a disk-like vibration plate (2 ' )
supported at a position along a concentric circle
differentiating two regions, an inner region and an outer
region. In the ultrasonic vibration apparatus, the disk-like
vibration plate (2 ' ) is constructed so as to be a part
of the casing (2) serving as the vibration face, and, the
piezoelectric element (1) is mounted in the central part of
the disk-like vibration plate (2 ' ), thereby causing the
inner region and the outer region to vibrate in
substantially the same phase.
Patent EP-1134906-A2 (EP)
Inventor: SAWA KAZUHIRO
IPC: H04B1/38
Filed: 2000-11-27
Abstract: Signals with transmission frequencies fta, ftb
from hand sets A, B are received by a receiver 20. The
whole frequency spectrum including the received signals
whose frequency is converted by the receiver 20 is inverted
by a signal processor 40. Then, the received signals
included in the frequency spectrum inverted by the signal
processor 40 is converted by a transmitter 30 and
retransmitted as signals with reception frequencies fra,
frb of the hand sets A, B. By using this communication
apparatus, a communication system with fixed duplex
intervals can be employed with a simple configuration at a
low cost, transmission/reception frequencies can be readily
set and duplex conversation between hand sets can be
achieved.
Patent EP-1111521-A2 (EP)
Inventor: YOKOTA IKUHIRO
IPC: H01L29/00
Filed: 2000-12-20
Abstract: Disclosed is a computer-implemented method for simulating a
semiconductor device, comprising steps of inputting physical constants of
the semiconductor device; performing iterative calculation in which
potential distribution, electron current density, and hole current density are
solved using a drift-diffusion model represented by charge conservation
equations, electron current continuation equations, and hole current
continuation equations; wherein each iteration of the calculation comprises
steps of: calculating an expansion amount of a band gap using an interim
solution to take into consideration a quantum effect in an inversion layer;
correcting potentials of electrons and holes with the expansion amount of
the band gap to take into consideration the quantum effect in the inversion
layer; wherein the expansion amount is obtained by steps of providing a
provisional term representing the expansion amount, based on a calculation
equation in accordance with a van Dort model; regarding the provisional
term as being caused by zeroth-order energy perturbation due to an electric
field perpendicular to an interface between a semiconductor and an
insulating film; adding one or more terms representing first- and/or
higher-order energy perturbation due to the electric field perpendicular to
the interface between the semiconductor and the insulating film to the
provisional term; and setting the sum of the addition as the expansion
amount.
Patent EP-1113270-A2 (EP)
Inventor: KAWAMURA TATSUROU
IPC: G01N21/49
Filed: 2000-12-27
Abstract: The object of the present invention is to measure a
concentration of protein stably at a temperature not higher
than 25°C, which is a possible ambient temperature at home,
and further to expand the measurable concentration range
while preventing an obstruction due to a suspending particle
such as a bubble and the like, using a reagent prepared by
mixing an acid in a solution containing tannin, tannic acid
and m-galloyl gallic acid. By mixing the reagent in a
solution to be detected to opacify the solution, intensities
of at least a transmitted light or a scattered light of the
solution to be detected is measured, and a protein
concentration thereof is determined based on the intensity.
The present invention also provides a method for measuring a
concentration of a solution and a method of urinalysis,
wherein a protein concentration is measured after measuring
an angle of rotation.
Patent EP-1022221-A2 (EP)
Inventor: LARDIERI SALVATORE
IPC: B65B39/00
Filed: 2000-01-11
Abstract: A device for distributing a set volume of a
material in powder form, comprising a body (1) that
defines a section acting as a passage (3) for this
material, first means (9) for closing this passage
which are hinged to the body (1), and actuating means
(11) connected to the first means of closure (9).
The device also comprises second means (14) for closing
a portion (13) of the passage section which are hinged
to the body (1) and engage in a leaktight manner in
at least one aperture (13) made in the first means of
closure (9), engaging with the latter in order to close
off the passage (3) completely, and corresponding
actuating means (17), independent of those of the
first means of closure (9), are connected to the
second means of closure (14).
Patent EP-1086659-A2 (EP)
IPC: A61C5/04
Filed: 1995-04-28
Abstract: An endodontic file for use in preparing a root canal
has a shank and a flexible working portion having
cutting edges which may be dulled at along one side
of the file. The working portion has a taper greater than
the ISO Standard of 0.02mm per mm of axial length. The
working portion is formed of nickel titanium alloy and may
be pre-curved.
Patent EP-1045331-A2 (EP)
Inventor: KATO RICK ALLAN
IPC: G06K7/14
Filed: 2000-03-21
Abstract: A method of deciphering bar codes is disclosed herein. The method
determines if the bar code (132) complies with predetermined specifications. The
method then sorts the bar code (132) information into character groups. Each
character group is reviewed individually to assure compliance with the
predetermined specification. The individual character groups are then decoded
individually. The method allows for bar code (132) specification to have varying
tolerances between the individual character groups, which increases the likelihood of
a bar code reader (400) being able to decipher the bar code (132).
Patent EP-1044619-A2 (EP)
Inventor: KITA KENJIRO
IPC: A43B13/12
Filed: 2000-04-13
Abstract: This invention provides a sole assembly for
an athletic shoe where the manufacturing process is
simplified. The sole assembly includes a midsole body (3)
extending from the heel part to the forefoot part of a shoe,
a corrugated sheet (4) bonded to the bottom surface of the
midsole body (3), and a lower midsole (3') bonded to the heel
portion of the corrugated sheet (4). A corrugation (4a) is
formed at the heel portion of the corrugated sheet (4) and
an outsole (5) on the forefoot side is integrally formed with
the forefoot portion of the corrugated sheet (4). An outsole
(5') on the heel side is bonded to the bottom surface of the
lower midsole (3').
Patent EP-1084624-A2 (EP)
Inventor: DAVIES DAVID
IPC: A23K3/03
Filed: 2000-09-18
Abstract: Plant material is converted to silage by treatment with new strains of
   Lactobacillus   plantarum    or    Lactobacillus   paracasei subspecies paracasei   
having fructan degrading properties.