baber/WOPTO huggingface dataset:
Patent AU-2020345000-A1 (AU)
Title: 1,4-dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine derivatives and related compounds as LRRK2, NUAK1 and/or TYK2 kinase modulators for the treatment of e.g. autoimmune disease
Inventor: KOESTLER ROLAND
IPC: A61P37/08
Filed: 2020-09-11
Abstract: The present invention relates to compounds of formula (I) that are capable of modulating, e.g., inhibiting or activating, one or more kinases, especially LRRK2 and/or NUAK1 and/or TYK2 or mutants thereof. The compounds are useful for treating diseases, such as autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, Alzheimer's disease, Parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 40 to 146; examples 1 to 63; compounds 1 to 248; tables 1 to 3). Preferred compounds are e.g. 1,4-dihydrobenzo[d]pyrazolo[3,4-f] [1,3]diazepine derivatives and related compounds. An exemplary compound is e.g. 5-(2,6-difluorophenyl)-8-methoxy-1,4- dihydrobenzo[d]pyrazolo[3,4-f][1,3]diazepine (example 49). (Formula (II):
Patent AU-2020348310-A1 (AU)
Title: Treatment of behavioral impairment in developmental and epileptic encephalopathy
Inventor: SEBREE TERRI
IPC: A61K36/185
Filed: 2020-09-16
Abstract: The present technology relates to methods of treating behavioral problems and seizures in a subject having developmental and epileptic encephalopathy (DEE) by transdermally administering an effective amount of cannabidiol (CBD) to the subject wherein behavioral problems are treated in the subject.
Patent AU-2020352836-A1 (AU)
Title: System and method for endoscopic video enhancement, quantitation and surgical guidance
Inventor: RAUNIYAR NIRAJ PRASAD
IPC: G06T3/40
Filed: 2020-08-27
Abstract: An endoscopic system includes an endoscopic imager configured to capture image frames of a target site within a living body and a processor configured to apply a spatial transform to a preliminary set of image frames, the spatial transform converting the image frames into cylindrical coordinates; calculate a map image from the spatially transformed image frames, each pixel position in the map image being defined with a vector of fixed dimension; align a current image frame with the map image and apply the spatial transform to the current image frame; fuse the spatially transformed current image frame to the map image to generate a fused image; and apply an inverse spatial transform to the fused image to generate an enhanced current image frame having a greater spatial resolution than the current image frame. The system also includes a display displaying the enhanced current image frame.
Patent AU-2020353676-A1 (AU)
Title: Methods for treating hyperphenylalaninemia
Inventor: SMITH NIEL
IPC: A61P3/00
Filed: 2020-09-25
Abstract: The invention features methods of reducing the blood phenylalanine concentration in a subject by administering sepiapterin, or a pharmaceutically acceptable salt thereof.
Patent AU-2020363647-A1 (AU)
Title: Optical coating for spectral conversion
Inventor: SONWALKAR NISHIKANT
IPC: H01L31/055
Filed: 2020-10-07
Abstract: An optical coating has a set of layers to reflect a predetermined range of wavelengths, the set of layers including two or more pairs of alternating first and second layers, the first layers having a first refractive index, m, and the second layers having a second refractive index, m, greater than the first refractive index m. The second layers each include a first distribution of nanoparticles of a first material. The layers exhibit a spectral characteristic that shifts a portion of the incident light to a first range of wavelengths and that directs light of the first range of wavelengths to a surface-enhanced Raman scattering (SERS) layer. The SERS layer is configured with a second distribution of conductive nanoparticles of a second material to further shift the light of the first range of wavelengths to a second range different from the first range, according to the second distribution of nanoparticles.
Patent AU-2020407666-A1 (AU)
Title: Collapsible wheels and methods of making collapsible wheels
Inventor: SOLHEIM JOHN A
IPC: B29D30/02
Filed: 2020-12-21
Abstract: Embodiments of collapsible wheels and methods of making collapsible wheels are generally described herein. Other embodiments may be described and claimed.
Patent AU-2020409427-A1 (AU)
Title: Airport advertising system
Inventor: ROGAN DENIS
IPC: G09F19/22
Filed: 2020-12-16
Abstract: An airport airside advertising system (1) displays advertising to passengers of adjacent commercial aircraft. An advertising billboard (7) or (7) A is disposed on the airside of an airport adjacent to a runway, taxiway or apron (2), (3), (4) and (12). The advertising billboard (7) or (7) A is configured to face a direction substantially perpendicular to the direction of movement of an adjacent aircraft (11) during landing, take off, taxiing or temporary parking thereof, the billboard (7) or (7) A dimensioned to display advertising visible to passengers in adjacent commercial aircraft (11). The advertising billboard (7) or (7) A has one or more sensor elements (8) associated therewith and configured to provide an actuation signal in response to detection by one or more sensor elements (8) of an adjacent aircraft (11) within a predetermined range.
Patent AU-2020410912-A1 (AU)
Title: A foot and lower leg cleaning and treatment device
Inventor: BERTANI ROMOLO LORENZO
IPC: A47K3/022
Filed: 2020-12-23
Abstract: A device for washing or treating the feet and lower legs of a user comprises an outer housing; a base assembly located in the outer housing; access means for providing access to a base assembly, a controller for controlling operation of the device, and a fluid supply mechanism. The base assembly includes a pair of footrests for supporting the feet and lower legs of a user during washing or treating, at least one rotatable transversely extending cleaning or treating assembly located above the footrest for washing or treating a user's feet; and a plurality of rotatable upright cleaning or treating assemblies for washing or treating the lower legs of the user. A tilting assembly is provided for tilting the base assembly relative to the outer housing through a plurality of inclined positions.
Patent WO-2022120422-A1 (WO)
Inventor: HENRY PETER CHARLES
IPC: B65D19/38
Filed: 2021-12-08
Abstract: A bulk fluid container assembly (1) formed of polymeric material having a bottom panel (44), a top panel (42), a side wall (40), an open-mouthed neck (20) on the top panel, a drainage opening (48), and a closure assembly (11). The closure assembly comprises a locking ring (28) to push upon a top face of a lid (26) interposed between the locking ring and neck to bear down upon a sealing element (24) interposed between an undersurface of the lid and a sealing surface of the neck whereby rotation of the locking ring causes compression of the sealing element without either surface rotating with respect to the sealing element.
Patent AU-2021213748-A1 (AU)
Title: Solid state forms of Mavacamten and process for preparation thereof
Inventor: KORDIĆ LORENA
IPC: A61K31/513
Filed: 2021-01-28
Abstract: The present disclosure encompasses solid state forms of Mavacamten, in embodiments crystalline polymorphs of Mavacamten, processes for preparation thereof, and pharmaceutical compositions thereof.
Patent AU-2021214442-A1 (AU)
Title: An ingestible therapeutic device for the treatment of gastritis
Inventor: TAHGHIGHI JAFARZADEH MASOUD
IPC: A61N5/06
Filed: 2021-02-01
Abstract: An ingestible gastrointestinal phototherapy device has a spherocylindrical body of non-digestible material having a cylindrical midsection and transparent light portals at ends thereof. The cylindrical midsection has control circuitry and a power source therein and each light portal is transparent and comprises an array of bioactive light source elements therein emitting bioactive light therefrom and being operably coupled to the control circuitry and power source.
Patent AU-2021218243-A1 (AU)
Title: Hydropower system for generating and storing energy
Inventor: SCHULTZ TONY JAMES
IPC: H02J15/00
Filed: 2021-08-23
Abstract: Disclosed is a pumped hydro energy storage system for generating and storing 
energy and method of operating a wastewater facility in conjunction with the 
5 pumped hydro energy storage system. The pumped hydro energy storage system 
comprises at least one upper water reservoir and a lower water reservoir and a 
penstock that interconnects the reservoirs. At least part of the lower reservoir may 
be a tunnel to accommodate wastewater and/or stormwater flow. The pumped 
hydro energy storage system also comprises at least one hydropower system for 
10 generating electricity by causing water to flow from the upper reservoir through 
one or more turbines into the lower water reservoir and a provides a pumping 
function for storing energy by pumping water up from the lower water reservoir.  
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Patent AU-2021229169-A1 (AU)
Title: Composite gypsum board and methods related thereto
Inventor: LI ALFRED C
IPC: C04B28/14
Filed: 2021-09-08
Abstract: AUDIVi 
ABSTRACT OF THE DISCLOSURE 
Disclosed is a composite gypsum board comprising a board core and a concentrated 
layer of substantial thickness (e.g., at least about 0.02 inches). The concentrated layer 
includes a higher weight percentage of an enhancing additive than the board core. The board 
core has a thickness greater than the thickness of the concentrated layer and forms the bulk of 
the board volume. The concentrated layer has a higher density (e.g., at least about 1.1 times 
greater) than the density of the board core. Also disclosed is a method of preparing a 
composite gypsum board.  
77
Patent AU-2021244009-A1 (AU)
Title: Pharmaceutical composition for preventing or treating epidemic RNA viral infectious disease
Inventor: RYU JEI MAN
IPC: A61K31/167
Filed: 2021-03-25
Abstract: The present invention relates to a use of pyronaridine or a pharmaceutically acceptable salt thereof, and/or artemisinin or a derivative thereof for preventing or treating an epidemic RNA viral infectious disease, and more specifically, to a pharmaceutical composition for preventing or treating an epidemic RNA viral infectious disease, in particular, Coronavirus Disease 2019 (COVID-19), the composition comprising a therapeutically effective amount of pyronaridine or a pharmaceutically acceptable salt thereof, and/or artemisinin or a derivative thereof, together with a pharmaceutically acceptable carrier.
Patent AU-2021245196-A1 (AU)
Title: Fractional initiator hybridization chain reaction
Inventor: PIERCE NILES A
IPC: C12Q1/68
Filed: 2021-10-07
Abstract: FRACTIONAL INITIATOR HYBRIDIZATION CHAIN REACTION 
ABSTRACT OF THE DISCLOSURE 
The present disclosure relates to methods and compositions involving HCR reactions 
that involve initiators that are split into two or more parts. Effective HCR is dependent upon 
two or more of these split initiators being brought into proximity (e.g., via binding events 
mediated by a target) such that a full initiator is formed that is capable of triggering HCR 
signal amplification.  
-71-
Patent AU-2021249587-A1 (AU)
Title: Electrolytic element for alkaline water electrolysis, and alkaline water electrolysis vessel
Inventor: TANAKA YASUYUKI
IPC: C25B1/04
Filed: 2021-03-23
Abstract: This electrolytic element for alkaline water electrolysis comprises: an electroconductive partition wall having a first surface and a second surface; an anode for oxygen generation; a cathode for hydrogen generation; a first connection means for fixing the anode to the partition wall and electrically connecting the anode to the partition wall such that the anode faces the first surface of the partition wall with a first interval therebetween; an electroconductive elastic body which supports the cathode; and a cathode current collector which supports the elastic body. The cathode current collector is fixed to the partition wall so as to face the second surface of the partition wall with a second interval therebetween, and is electrically connected to the partition wall. The first connection means includes an electroconductive bolt having at least a shaft part, and the anode is detachably fixed to the partition wall via the electroconductive bolt.
Patent AU-2021265179-A1 (AU)
Title: Surgical assembly designed to reduce a bone fracture
Inventor: BALLERINI JULIEN
IPC: A61B17/68
Filed: 2021-04-29
Abstract: The present invention relates to a surgical assembly for reducing a fracture situated at bone epiphyses or joints comprising: an osteosynthesis support plate (1), a set of diaphyseal fixing members (12), a set of cannulated epiphyseal fixing members (20), a set of fixing pins (40), at least one cannulated sighting guide (30, 30a), a cannulated tool (50) for rotating the fixing members (12, 20) and the sighting guides (30, 30a), also acting as a measuring instrument (for determining the length of at least some of the epiphyseal fixing members (20) to be used), a cannulated drilling device (for drilling holes suitable for positioning at least some of the fixing members (20)) and, preferably, an arthroscopic device designed to allow the practitioner to view some of the operative phases.
Patent AU-2021281131-A1 (AU)
Title: Device for capturing guide wires
Inventor: RIGHINI GIOVANNI
IPC: A61B17/221
Filed: 2021-05-26
Abstract: A device (10) for capturing a guide wire (50) comprises a snaring device (20, 30) and an auxiliary catheter (40). The auxiliary catheter (40) is configured to slidingly accomodate the guide wire to be caught so as to extend a distal end (47) thereof beyond the distal end of the guide wire in order to be caught by the snaring device (20, 30) while the guide wire (50) is in a retracted position in the auxiliary catheter (40). The auxiliary catheter preferably comprises a portion which is at least partially echo-transparent and/or radio- transparent and an end portion (44) which is radio-opaque and/or echo-opaque.
Patent AU-2021281592-A1 (AU)
Title: Coupled terpene conjugate
Inventor: BUCHY ERIC
IPC: A61K47/54
Filed: 2021-05-20
Abstract: The present invention concerns the use of a linear or optionally branched terpene having at most one C=C unsaturation for producing conjugates having self-assembly properties, and a self-assembly agent of formula (I): X(-Spacer-Y-Terpene)p (I) in which "Terpene" is linear or optionally branched and has at most one C=C unsaturation; "Y" is a bond or a molecular fragment having a biodegradable bond; "Spacer" is a bond or a fragment comprising at least one carbon atom; "X" is a molecular fragment comprising at least one biodegradable bond; "p" is between 0.1 and 4; and the group "Spacer-Y-" may optionally be a bond; and also the conjugate obtained by combining the self-assembly agent of formula (I) with an active molecule AM.
Patent AU-2021298025-A1 (AU)
Title: Method for power prediction of an energy system
Inventor: DÖLLE OLIVER
IPC: H02J13/00
Filed: 2021-05-03
Abstract: The invention relates to a method for determining an aggregation of power profiles P
Patent AU-2021321536-A1 (AU)
Title: Kinase inhibitors and uses thereof
Inventor: CHEN CHEN
IPC: A61P25/28
Filed: 2021-08-06
Abstract: Provided are cyclic iminopyridimdine compounds and their bicyclic derivatives, pharmaceutical compositions comprising such compounds, and methods of using such compounds or compositions, such as methods of treating a proliferation disorder, such as a cancer or a tumor, or in some embodiments disease or disorders related to the dysregulation of kinase such as, but not limited to kinases such as MAPK, PDGFR, Src, PAKs, c-Kit, EphA2, EphB4, FGFR, Axl, and c-Met.
Patent AU-2021323398-A1 (AU)
Title: Augmented reality or virtual reality system with active localisation of tools, use and associated process
Inventor: GARRIDO JURADO SERGIO
IPC: G09B19/24
Filed: 2021-07-30
Abstract: An augmented reality or virtual reality system with active localisation of tools, use and associated procedure. The invention discloses an augmented/virtual reality (AR/VR) system, comprising: an object (1) with one or more optical markers (7, 8) disposed thereon; a tool (2); an AR/VR viewer (3); a first optical means (4) of information acquisition; and a processing unit (5) connected at least to the tool (2) and the AR/VR viewer (3). Advantageously, the tool (2) comprises a second optical means (6) of data acquisition, in such a way that the system operates even when there are objects occluded from the viewer (3). The processing unit (5) receives the information acquired by the first optical means (4) and/or the second optical means (6), processes same and on the basis thereof calculates a virtual trajectory with information related to the trajectory covered by the tool (2) in real space.
Patent AU-2021327166-A1 (AU)
Title: Off-gas utilization in electrically heated reforming plant
Inventor: MORTENSEN PETER MØLGAARD
IPC: C01B3/38
Filed: 2021-08-19
Abstract: A plant and a method are provided in which a first feed comprising hydrocarbons is subjected to electrical steam methane reforming (e-SMR) to generate a first syngas stream. An upgrading section receives the syngas stream and generates a first product stream and an off-gas stream from the syngas stream. A power generator receives at least a portion of the off-gas stream and/or a portion of said first product stream from the upgrading section and/or a portion of said first feed and generates a second electricity flow. At least a portion of the second electricity flow is arranged to provide at least a part of the first electricity flow to the e-SMR reactor.
Patent AU-2021342132-A1 (AU)
Title: Processes and intermediates for the preparation of (s)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropane-2-yl)-1H-pyrazole-4-carboxamide
Inventor: ARGUELLES DELGADO ALONSO JOSE
IPC: C07C235/60
Filed: 2021-09-09
Abstract: The present invention provides processes and key intermediates for the synthesis of (S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropane-2-yl)-1H-pyrazole-4-carboxamide.
Patent AU-2021377210-A1 (AU)
Title: High affinity human and monkey specific tfr-1 vnars
Inventor: STOCKI PAWEL
IPC: A61K39/00
Filed: 2021-11-09
Abstract: The present invention relates to a high affinity, VNAR polypeptide cross reactive with primate transferrin receptors ("TfR"). This TfR-specific VNAR polypeptide was obtained by screening semisynthetic VNAR phage display libraries against recombinant human TfR-1. The VNAR polypeptides of the invention can be used alone or as a component in conjugates that target the transferrin/transferrin receptor transport system. The invention further includes use of this VNAR, its conjugates and other derivatives in diagnostic and therapeutic methods, e.g., to diagnose, treat and/or prevent a pathological condition, disorder or disease in which it is beneficial to deliver a heterologous biomolecule across the blood brain barrier or other membrane systems. This TfR-specific VNAR polypeptide can also be used to target other biological barriers such the intestines, the placenta or aberrant cells overexpressing TfR-1, for therapeutic benefit in treatment of certain cancer cells and tumors of various tissue types. Deimmunized VNAR scaffolds are also provided.
Patent AU-2021392062-A1 (AU)
Title: Method for carbon dioxide capture and sequestration using alkaline industrial wastes
Inventor: WANG BU
IPC: B01D53/96
Filed: 2021-05-12
Abstract: A method of sequestering gaseous carbon dioxide in which an oxide is carbonated by contacting it with a first aqueous carbonate solution to convert a portion of the oxide into a carbonate, which precipitates from solution. By converting the oxide to a solid carbonate, the CO
Patent AU-2021395712-A1 (AU)
Title: Multi-shell helmet with pivotable outer shell
Inventor: CRIPTON PETER ALEC
IPC: A42B3/06
Filed: 2021-12-10
Abstract: Helmet prevent or mitigate cervical spine fractures, including the type of injuries associated with axial compression of the spine and fracture of the spine which may otherwise result in deformation and/or injury to the spinal cord. Helmets convert an impact force with a component aligned with the axis of the spine (a "spinally axial component") to rotational motion. In the event of a head-first impact, such helmets flexion of the neck so that the head and the cervical spine are not aligned (or less aligned) with the direction of an impact force, thereby mitigating the likelihood and/or severity of cervical spine fractures.
Patent AU-2021398051-A1 (AU)
Title: Crystal form of tolebrutinib, preparation method therefor and use thereof
Inventor: CHEN MINHUA
IPC: C07D471/04
Filed: 2021-11-22
Abstract: Provided are a crystal form of Tolebrutinib (hereinafter referred to as "compound I"), a preparation method therefor, a pharmaceutical composition containing the crystal form, and the use of the crystal form in the preparation of a BTK inhibitor drug and a drug for treating multiple sclerosis. The crystal form of Tolebrutinib has one or more improved properties compared with the prior art, and is of great value to the optimization and development of the drug in the future.
Patent AU-2021404426-A1 (AU)
Title: Systems and methods for hyperspectral imaging of plants
Inventor: ROTHWELL AUSTIN CAULFIELD
IPC: G01N21/25
Filed: 2021-12-17
Abstract: Systems and methods for hyperspectral imaging of plants are provided. Multispectral images of plants are transformed, e.g. by interpolation along a spectral axis, to generate hyperspectral images of plants. The transformation can be based on spectral bases formed from hyperspectral sample images including images of plant matter. Plant characteristics, such as plant health, may be predicted based on the hyperspectral image. Plant health may be predicted by comparing derivatives of reflectance values with respect to wavelength for a plant of a given image relative to a reference derivative based on a reference hyperspectral image. The derivatives may be compared by determining a regression loss.
Patent AU-2021458928-A1 (AU)
Title: Self-traveling robot transfer system and transfer robot for use in same
Inventor: MANABE TATSUYA
IPC: E04G21/12
Filed: 2021-09-30
Abstract: Provided are: a self-traveling robot transfer system in which, when a reinforcing rod binding self-traveling robot reaches, while self-traveling on a reinforcing rod as a traveling track, the vicinity of the end of the reinforcing rods, the self-traveling robot is caused to self-travel inversely on another reinforcing rod as a new traveling track without letting an operator lift the self-traveling robot, and consequently reiteration work by the self-traveling robot is achieved easily; and a transfer robot for use in the system. A self-traveling robot transfer system 100 is provided with: a transfer robot 110 for demountably mounting thereon a self-traveling robot which travels on a reinforcing rod as a traveling track; and a pair of traverse rails 120. The transfer robot is integrally formed from: a body unit 112 comprising body driving wheels which roll on the traverse rails, a body frame which moves on the traverse rails by the body driving wheels, and a traverse drive part which drives the body driving wheels; and a cart unit 111 comprising cart wheels which roll on the traverse rails, a cart frame which moves on the traverse rails by the cart wheels, and a mounting assist frame which transfer the self-traveling robot, in a manner as to be mountable and demountable, between a second reinforcing rod and the cart frame.