baber/WOPTO huggingface dataset:
Patent IL-73696-A0 (IL)
Title: Indole derivatives,their preparation and pharmaceutical compositions containing them
IPC: A61P9/06
Filed: 1984-11-30
Abstract: This invention relates to novel indole derivatives of the formula <IMAGE> (I)  wherein A represents a -CH2-CH2-, -CH=CH-,   <IMAGE> group and B represents a methylene, carbonyl, or thiocarbonyl group or A represents a -CO-CO- or   <IMAGE>   group and B represents a methylene group, E represents an alkylene group or a 2-hydroxy-n-propylene, 2-hydroxy-n-butylene, or 3-hydroxy-n-butylene group, G represents an alkylene group, R1 represents a hydrogen, chlorine, or bromine atom or a trifluoromethyl, nitro, amino, alkylamino, dialkylamino, alkyl, hydroxyl, alkoxy, or phenylalkoxy group, R2 represents a hydrogen, chlorine, or bromine atom or a hydroxyl, alkoxy, phenylalkoxy, or alkyl group or R1 and R2 together represent an alkylenedioxy group, R3 represents a hydrogen, chlorine, or bromine atom or an alkyl group, R4 represents a hydrogen atom or an alkyl or phenylalkyl group, R5 represents a hydrogen, fluorine, chlorine, or bromine atom or an alkyl, hydroxyl, alkoxy, or phenylalkoxy group, R6 represents a hydrogen atom or an alkoxy group, and R7 represents a hydrogen atom or an alkenyl, alkyl or phenylalkyl group, and the acid additional salts thereof. These compounds, which may be obtained by use of known methods, have valuable pharmacological properties, particularly a heart rate-lowering activity.
Patent IL-78703-A0 (IL)
Title: Bacterial enzymes
IPC: C12N9/16
Filed: 1986-05-06
Abstract: Extracellular Serratia spp. enzymes have been found to be excreted by another gram-negative organism harbouring a plasmid carrying DNA from Serratia spp. encoding the enzymes. This organism, eg. E. coli, is therefore employed to produce the enzymes, specific examples of Serratia spp. enzymes produced are a nuclease, a lipase and a phospholipase. The nuclease may be employed to remove nucleic acids from a biological material.
Patent IL-80908-A0 (IL)
Title: Tricyclic pyridazopyridone derivatives,their preparation and medicaments containing them
IPC: C07D513/00
Filed: 1986-12-08
Abstract: The compounds of the formula    <IMAGE>  I  wherein Ra,Rb,RcRd are defined in the specification and pharmaceutically acceptable addition salts are disclosed. The compounds of formula I have valuable pharmacological properties and can be used for the control of prevention of illnesses. In particular, they have muscle relevant, seditive-hypnotic, anxiolytic and/or anticonvulsive activity and can accordingly be used in the control or prevention of muscle tensions, stress conditions, isomnia, anxiety states and/or convulsions.
Patent IL-90640-A0 (IL)
Title: Method of controlling plant pests
IPC: A01H5/00
Filed: 1989-06-16
Abstract: The present invention relates to a process for controlling plant pests, which is based on proteinase inhibitors which are synthesized in the plant as a result of genetic manipulation. It also relates to transgenic mono- and dicotyledonous plants which contain genes which encode proteinase inhibitors or their precursors, and plants which express these genes and a process for controlling plant pests by exposing these to such a transgenic plant. The invention further relates to DNA sequences and vectors which contain these sequences and which encode proteinase inhibitors.
Patent IL-94665-A0 (IL)
Title: N-heteroaryl-purin-6-amines,process for their preparation and their use as medicaments
IPC: A61K31/7052
Filed: 1990-06-07
Abstract: This invention relates to a N-heteroaryl-purin-6-amine of the formula   <CHEM> where R1 is hydrogen, lower alkyl, and arylloweralkyl; R2 and R3 are independently hydrogen, lower alkyl or R2 and R3 taken together are aryl; R4 and R5 are independently hydrogen, lower alkyl, or R4 and R5 taken together are aryl; R6 is hydrogen, lower alkyl, aryl, arylloweralkyl, <CHEM> where R2, R3, R4 and R5 are as defined above, and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention display utility as analgesic and anticonvulsant agents.
Patent IL-98862-A0 (IL)
Title: Process for the preparation of biphenylcarbonitrile derivatives
IPC: C07D401/12
Filed: 1991-07-16
Abstract: The invention provides a novel process for the manufacture of biphenylcarbonitriles of the formula III as defined hereinafter which are useful for the production of certain known imidazole derivatives and certain novel quinoline derivatives which have angiotensin II inhibitory activity. The process involves a palladium- or nickel-catalysed reaction of a boron compound of the formula II with a nitrile of the formula III in which the variables L<1>, L<2>, Q<1> and Q<2> have the various meanings defined hereinafter. Certain of the biphenylcarbonitriles are novel and are provided as a further feature of the invention. The invention also provides a novel process for the production of the known and novel angiotensin II inhibitors of formula VI and VII as defined hereinafter.
Patent AU-PN455495-A0 (AU)
Title: Improvements in or relating to valves
IPC: E03D1/30
Filed: 1995-08-02
Abstract: There is described a valve arrangement which in one form is an inlet valve (60) or in another form is a dual flush valve (2). The valves may be used in a variety of situations but find particular application in a cistern for providing water to flush a toilet bowl or similar. The valve arrangement (2) comprises a flushing tube (100) or a pair of flushing tubes  (14, 18) which can move axially. One end of the tubes (100, 18) is sealed to an outlet (9). The tubes are provided with rings or collars (16, 22) which co-operatively engage with locking edges (48, 50) of floats (40, 44) to control movement of the tubes (100, 14, 18). The floats (40, 44) are mounted off-centre or in a position spaced apart from their respective centres of gravity so that they are free to move under the effects of gravity and the effects of lift provided by buoyancy of the floats. In operation the sequential effects of gravity and buoyancy cause the floats to hold the tubes in position and then release the tubes thereby allowing selective flushing positions.
Patent AU-PP266198-A0 (AU)
Title: Simultaneous binocular assessment of multiple optic nerve and cortical regions in diseases affecting nerve conduction
IPC: G06F3/00
Filed: 1998-03-30
Abstract: This invention concerns the detection of neural damage to the optic nerve, optic radiations and white matter of the visual brain indicative of various neurological disorders but with particular application to multiple sclerosis. The method involves simultaneous measurement of the shape and latency of responses to visual stimuli presented simultaneously in different parts of the visual field of the two eyes, separating out linear and nonlinear response components, and most particularly separating out binocular interaction responses to assess neural function within each half of the visual cortex. Because rough retino-topicity is maintained in the optic nerve, through the optic radiations and the visual cerebral cortex, stimulation of the separate parts of the visual field permits isolation of responses from different component parts of these neural elements and therefore from the results obtained an objective assessment of damage to these separate neural components can be made simultaneously.
Patent FI-20000752-A0 (FI)
Inventor: XU LIN
IPC: H04W88/14
Filed: 2000-03-31
Abstract: A method for routing data packets (DP) to a mobile node (MN) from its correspondent node (CN), via a multi-bearer network, or MBN. The MBN comprises uplink bearer networks (GSM, GPRS, UMTS) and downlink bearer networks (DxB). The method comprises: 1) storing an address (202) associated with a centralized traffic policy controller (TPC) as the mobile node's care-of address in its home agent (HA); 2) routing an initial data packet via the home agent and the centralized traffic policy controller to a bearer network interface unit (DxB_IU, DL_IU) serving the mobile node; 3) storing an address (214) of the bearer network interface unit as the mobile node's care-of address in the correspondent node (CN); 4) routing subsequent data packets from the correspondent node (CN) to the bearer network interface unit (DxB_IU, DL_IU), whereby the home agent (HA) and the centralized traffic policy controller are bypassed.
Patent IL-103017-A0 (IL)
Title: Apparatus and process for producing folded sheet articles
IPC: B31D5/00
Filed: 1992-09-02
Abstract: Apparatus for use in producing an article comprising a sheet of material, characterised in that it contains means to stiffen a portion only of said sheet by an addition thereto of non-stiff matter and possibly curing the same. <IMAGE>
Patent IL-109206-A0 (IL)
Title: Solid crop protection formulations
IPC: A01N53/08
Filed: 1994-04-04
Abstract: A method of combating aphid pests at a locus is disclosed, the method comprising applying to the locus an aqueous dispersion prepared by dispersing a solid concentrate which comprises polyvinylpyrrolidone and a pyrethroid insecticide in water.
Patent IL-111625-A0 (IL)
Title: Phosphoric esters for use as crystallisation inhibitors
IPC: A01N57/12
Filed: 1994-11-14
Abstract: Phosphoric acid esters of the formula <IMAGE>  in which     R<1> represents alkyl having 2 to 18 carbon atoms and R<2> and R<3> independently of one another represent alkyl having 2 to 12 carbon atoms can be used for the application of aqueous spray mixtures which comprise   A) certain azole derivatives which have a tendency to crystallise and   B) if appropriate one or more other active compounds as well as additives to prevent crystallisation of these active compounds, in the spray equipment, which have a tendency to crystallise.
Patent IL-112766-A0 (IL)
Title: Methods for controlling human endothelial cell proliferation and effector functions using oncostatin m
IPC: A61K38/27
Filed: 1995-02-23
Abstract: The present invention is directed to the use of a recently discovered cytokine, Oncostatin M, to control endothelial cell immunogenicity, fibrinolytic activity, proliferation and cytokine synthesis, and to its use in the treatment of a variety of human vascular and immune system disorders involving the vascular endothelium, as well as its use in the treatment of neoplastic disease. The method of the invention includes the use of mature, hybrid, modified or truncated forms of Oncostatin M as well as Oncostatin M analogs. The invention is described by way of examples in which the efficacy of such compounds is evaluated using various in vitro assay systems.
Patent IL-116779-A0 (IL)
Title: Method of incorporating added ingredients with animal foodstuffs
IPC: A23K1/00
Filed: 1996-01-16
Abstract: A method of adding a medicament (or other added ingredient) to animal feed pellets is described, in which the medicament is contained in a cohesive gel which is mixed with the feed pellets. The gel coats the pellets substantially homogeneously, and leaves little contamination of the mixing vessel. Preferably, the gel has a viscosity in the range 5,000 to 20,000 cP, and is added to the feed pellets in an amount of between 2 and 40 kg/tonne.
Patent IL-133824-A0 (IL)
Title: Tetrazole derivatives, medicaments containing same and use thereof
IPC: A61P1/00
Filed: 1998-07-18
Abstract: Compounds of formula I,in which R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings indicated in the description, are efficacious bronchial therapeutics.
Patent IL-147652-A0 (IL)
Title: Novel peptides
IPC: A61K48/00
Filed: 2000-07-24
Abstract: The present invention provides a novel peptide-type compound which induces secretion of growth hormone and which has the activity of increasing the intracellular calcium ion concentration, wherein at least one amino acid is replaced by a modified amino acid and/or a non-amino acid compound, or a pharmaceutically acceptable salt thereof.
Patent IL-151495-A0 (IL)
Title: Device and method for the production of three-dimensional objects
IPC: C12M1/40
Filed: 2000-12-01
Abstract: A device and a process for producing three-dimensional objects is disclosed. The device has a container ( 1 ) for a medium ( 2 ) and a three-dimensionally positionable dispenser ( 4 ) for release of a material ( 3 ), the addition of which to the medium ( 2 ) leads to the formation of solid structures, into the medium ( 2 ). Addition of the material ( 3 ) by moving the dispenser in XYZ direction on a platform ( 8 ) below the filling height of the first material ( 2 ) in the container ( 1 ) leads to the formation of three-dimensional objects.
Patent IL-165809-A0 (IL)
Title: Substituted heterocyclic compounds and pharmaceutical compositions containing the same
IPC: A61K31/42
Filed: 2004-12-16
Abstract: Compounds are provided which are useful as antidiabetic agents and antiobesity agents and have the structure wherein m is 0, 1 or 2; n is 0, 1 or 2; Q is C or N; A is (CH2)x where x is 1 to 5, or A is (CH2)x1 where x1 is 1 to 5 with an alkenyl bond or an alkynyl bond embedded anywhere in the chain, or A is -(CH2)x2-O-(CH2)x3- where x2 is 0 to 5 and x3 is 0 to 5, provided that at least one of x2 and x3 is other than 0; B is a bond or is (CH2)x4 where x4 is 1 to 5; X is CH; X2 is N; X3 is C; X4 is N; X5 is C; X6 is C.
Patent IL-181808-A0 (IL)
Title: Method and an apparatus to cut out a vehicle glazing panel
IPC: B60J1/00
Filed: 2007-03-08
Abstract: A winder unit (1) is disclosed for use with a cutting wire in cutting out a vehicle glazing panel. The unit is capable of being mounted to the glazing panel and includes first and second winder spools (4,5) for winding cutting wire. At least one wire wrap around guide element (typically a pulley) is positioned away from the mounting means wherein 
i) the wire is secured to a single spool only of the unit and, with the wire connected to the single connected spool only, a cut is effected with the unit in a first mounted position; and the unit is moved to a second mounted position with the wire remaining connected to the single connected spool only, prior to further cutting; and/or 
ii) one or both spools are provided with a respective ratchet mechanism, the ratchet mechanism being released during the procedure such that the wire becomes slackened. 
The unit (1) may be used in various techniques either alone or with an auxiliary guide arrangement (2).
Patent IL-182297-A0 (IL)
Title: The use of winter savory (satureja montana) or the extracts thereof for the preparation of medicaments for the treatment of the premature ejaculation
Filed: 2007-03-29
Abstract: The use of Winter savory or its purified extracts rich in rosmarinic acid, the use of rosmarinic acid and the extracts containing it for the preparation of medicaments for the treatment of premature ejaculation.
Patent IL-186053-A0 (IL)
Title: Minimizing memory barriers when enforcing strongly-ordered requests in a weakl y-ordered processing system
Filed: 2007-09-18
Abstract: The disclosure is directed to a weakly-ordered processing system and method for enforcing strongly-ordered memory access requests in a weakly-ordered processing system. The processing system includes a plurality of memory devices and a plurality of processors. A bus interconnect is configured to interface the processors to the memory devices. The bus interconnect is further configured to enforce an ordering constraint for a strongly-ordered memory access request from an originating processor to a target memory device by sending a memory barrier to each of the other memory devices accessible by the originating processor, except for those memory devices that the bus interconnect can confirm have no unexecuted memory access requests from the originating processor.
Patent IL-186169-A0 (IL)
Title: Charged lipoprotein complexes and their uses
Filed: 2007-09-23
Abstract: The present disclosure provides charged lipoprotein complexes that include as one component a negatively charged phospholipid that is expected to impart the complexes with improved therapeutic properties.
Patent AP-2002002671-A0 (AP)
Title: Protease inhibitors.
Inventor: MARQUIS ROBERT WELLS JR
IPC: A61P33/02
Filed: 2001-06-14
Abstract: The present invention provides 4-amino-azepan-3-one protease inhibitors and pharmaceutically acceptable salts, hydrates and solvates thereof which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, novel intermediates of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia of malignancy; and metabolic bone disease, comprising inhibiting said bone loss or exces-sive cartilage or matrix degradation by administering to a patient in need thereof a compound of the present invention.
Patent ZW-6792-A1 (ZW)
Title: Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles
Inventor: JAMIN HUANG
IPC: C07D401/12
Filed: 1992-04-29
Abstract: Pyrazoles of formula (I) are new. In (I), R1 = CN, NO2, halo, formyl, alkycarbonyl or cycloalkylcarbonyl; R2 = halo, alkyl, haloalkyl, alkoxy, haloalkoxy, NO2, thiocyanate, (or optd. mono- or di-alkyl substd.) sulphamoyl, or aminocarbonyl, alkoxycarbonyl or opt. substd. R9S(O)n; n = 0 to 2; R9 = alkyl, haloalkyl, cycloalkyl, halocycloalkyl, cyclo-alkyl- alkyl or halocycloalkyl alkyl; R3 = H, alkyl, alkoxy, alkylthio or di alkylamino; R4 = phenyl or 5-6 membered O,S and/or N, heteroaryl both opt. substd with -OH or a salt, -SH or a salt, halo, CN, NO2, alkyl, haloalkyl, alkoxy, -O- alkyl-O-, -O-halo alkyl-O-, haloalkoxy, alkanoyloxy, phenolic, tri-alkylsiloxy, phenyl, alkyl-S(O)n, halo alkyl-S(O)n, NR10R11, COR12, SO2R13; R10,R11 = H, alkyl, alkanoyl or haloalkanoyl; R12 = NR10R11 alkoxy, alkylthio, OH or a salt, H, alkyl or halo alkyl; R13 = NR10R11, alkoxy, alkylthio or OH or a salt; R5 = halo or alkyl; R6, R8 = H or F; R7 = H, alkyl, haloalkyl, alkoxy, haloalkoxy, CN, NO2, alkylcarbonyl, haloalkylcarbonyl, alkyl-S(O)n or halo alkyl-S(O)n; X = N or CR14; R14 = H, halo, CN, NO2, alkyl, alkylthio or alkoxy; where alkyl = 1-4C alkyl and cycloalkyl = 3-7C cycloalkyl. 17 Cpds. (I) are claimed e.g. 1-(2,6-dichloro-4-trifluoro methyl phenyl)-3-cyano-4- trifluoromethylsulphenyl-5- (4-hydroxy-3-methoxyphenyl) methylideneimino)pyrazole (Ia).
Patent IE-910661-A1 (IE)
Title: Method for purifying somatotropin monomers
Inventor: STORRS STEPHEN BRADLEY
IPC: C12P21/02
Filed: 1991-02-27
Abstract: A method for purifying and recovering biologically active somatotropin monomers from refold solution following the solubilization and naturation of refractile bodies of host cells produced by recombinant DNA methodology. The purification process is based on the discovery that somatotropin monomers and somatotropin oligomers having overlapping isoelectric points may nevertheless be separated by selective precipitation over a narrow pH range. Host cell residues including proteins, pyrogens and other impurities present in the refold solution are effectively removed in the process. The purified somatotropin monomers recovered from solution after removing precipitated solids are suitable for parenteral application to target animals without further purification.
Patent MA-40709-A1 (MA)
Title: Dérivé du glucagon à stabilité améliorée
Inventor: JUNG SUNG YOUB
IPC: C07K14/605
Filed: 2015-12-30
Abstract: La présente invention concerne un nouveau peptide dérivé du glucagon, ainsi qu'une composition destinée à la prévention ou au traitement de l'hypoglycémie et de l'obésité, comprenant le peptide en tant que principe actif. Le dérivé de glucagon de la présente invention présente une activité maintenue dans le temps contre les récepteurs du glucagon et présente des propriétés physiques améliorées en raison d'une modification de son point isoélectrique, et est ainsi capable d'améliorer l'utilisation conforme
Patent UY-23898-A1 (UY)
Title: Equipo electronico de control de velocidad de vehiculos y sistema acoplado
IPC: G08G1/052
Filed: 1995-01-31
Abstract: Se describe un equipo electrónico de control de velocidad de vehículos y sistema acoplado caracterizado por comprender un sensor de presencia de vehículos en movimiento; un procesador electrónico para determinar la velocidad de los vehículos, comparar sus velocidades con un límite máximo previamente estableciudo y controlar un indicador de velocidad de cada vehículo; un módulo de indicación y alarma capaz de identificar fotograficamente, por medio de una cámara un vehículo cuya velocidad esté por encima del límite máximo establecido; y un sistema acoplado constituido por un transmisor ubicado en el módulo y de receptores, ubicados en los vehículos y activados por el transmisor para informar la velocidad máxima admitida en el lugar o avisar a los conductores de la proximidad de otros lugares tales como cruces peligrosos, puestos de policia caminera, restaurantes, estaciones de servicios y otros. La figura 1 es una vista esquemática de una primera representación del equipo en una calle con dos vías (mano y contramano).
Patent UY-26318-A1 (UY)
Inventor: ZIEGLER JOHANNES BARTHOLOMAUS
IPC: A61K9/50
Filed: 2000-08-31
Abstract: A controlled-release oral dosage formulation of a salt-forming active ingredient, wherein the active ingredient is present as at least two different salts in a solid aggregation state, wherein the two different salts have different water solubility and release the active ingredient in-vitro at different release rates, provided that oral dosage formulations are excluded which comprise a resin carrying a sulfonate group and a resin carrying a carboxyl group and which contain an active ingredient in a form fixed to these resins.
Patent UY-26328-A1 (UY)
Title: Derivados de amino-triazolopiridina
Inventor: RIEMER CLAUS
Filed: 2000-09-05
Abstract: La invención se refiere a compuestos de la fórmula I y sus sales farmacéuticamente aceptables, útiles para el tratamiento de enfermedades relacionadas con el receptor de adenosina o para la elaboración de los medicamentos correspondientes.
Patent UY-26436-A1 (UY)
Title: Salto de frecuencia en sistemas de comunicaciones compactos gprs/gsm
Inventor: PERSSON BENGT
IPC: H04B7/26
Filed: 2000-11-15
Abstract: Técnicas para realizar salto de frecuencia en un sistema de comunicaciones inalámbrico por Acceso Múltiple por División de Tiempo (Time División Múltiple Access - TDMA), que emplea una reutilización de frecuencia y de tiempo permiten el salto de frecuencia en todas las porciones de tiempo del sistema, permitiendo en consecuencia saltos de frecuencia exitosos aún para asignaciones de porciones múltiples a una sola estación móvil. Un procedimiento ejemplar incluye las etapas de asignar un primer tipo de canal lógico a una frecuencia simple en una porción de tiempo compartida, y asignar un segundo tipo de canal lógico a una secuencia de salto de frecuencia que incluye al menos dos frecuencias en la misma porción de tiempo compartida.
Patent UY-27240-A1 (UY)
Title: Marca de oreja para ganado con sistema de toma de muestras de materia orgánica
Inventor: DESTOUMIEUX JEAN JACQUES
Filed: 2002-04-03
Abstract: Marca de oreja para ganado compuesta por una parte hembra constituida por un cabezal hembra (6) incluida o montada en una primera pared (1), una parte macho constituida por un vástago macho (2) incluida o montada en una segunda pared (1), y medios de identificación presentes al menos en uno de los elementos macho o hembra. El vástago macho (2) posee dos elementos separables, uno de ellos se traba en el cabezal hembra y el otro, en el pasaje del vástago macho (2) a través de la pared de la oreja,opera como un instrumento de extracción de materia orgánica móvil en el canal axial del anterior y se retira a través de pared (1) de la parte macho luego de la fijación de la marca en la oreja del animal.