Patent SG-11201807334S-A (SG)
Title: Methods, compositions, and devices for information storage
Inventor: PREDKI PAUL
IPC: C12Q1/68
Filed: 2017-02-28
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD 1111101110101011111 HO 11111 01E3 Ell OH 10111110110111110111011 International Bureau ... .... ..Yjd ...... ... (10) International Publication Number (43) International Publication Date WO 2017/151680 A2 8 September 2017 (08.09.2017) WIP0 I PCT (51) (21) (22) (25) Filing Language: (26) Publication Language: (30) (71) (72) International Patent Classification: (81) Designated States (unless otherwise indicated, for every C07H 21/04 (2006.01) GO6F 19/20 (2011.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, PCT/US2017/020044 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, International Filing Date: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, 28 February 2017 (28.02.2017) KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, English NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, English RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, Priority Data: ZA, ZM, ZW. 62/301,538 29 February 2016 (29.02.2016) US 62/415,430 31 October 2016 (31.10.2016) US (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, Applicant: DODO OMNIDATA, INC. [US/US]; Suite GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, 104-118, 1501 San Elijo Road S, San Marcos, California TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, 92078 (US). TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, Inventors: PREDKI, Paul; c/o DODO OMNIDATA, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, INC., 1501 San Elijo Road S, Suite 104-118, San Marcos, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, California 92078 (US). CASSIDY, Maja; c/o DODO OM- NIDATA, INC., 1501 San Elijo Road S, Suite 104-118, GW, KM, ML, MR, NE, SN, TD, TG). San Marcos, California 92078 (US). Published: Agent: HOXIE, Thomas; Hoxie & Associates LLC, 75 — without international search report and to be republished Main Street, Suite 203, Millburn, New Jersey 07041 (US). upon receipt of that report (Rule 48.2(g)) = = (74) — (54) Title: METHODS, COMPOSITIONS, AND DEVICES FOR INFORMATION STORAGE (57) : The disclosure provides a novel system of storing information using a charged polymer, e.g., DNA, the monomers of which correspond to a ma- chine-readable code, e.g., a binary code, and which can be synthesized and/or read using a novel nanochip device compris- ing nanopores; novel methods and devices for synthesizing oligonucleotides in a nanochip format; novel methods for synthesizing DNA in the 3' to 5' direction using topoisomerase; novel methods and devices for reading the sequence of a charged polymer, e.g., DNA, by measur- ing capacitive variance as the polymer passes through the nanopore; and further provides compounds, compositions, methods and devices useful therein. = = _ = OFF = = = = = = = — ei © GC 11 Ilt) ,-1 IN ,-1 0 ei FIG. 1 0