baber/WOPTO huggingface dataset:
Patent DE-69223455-D1 (DE)
Inventor: INAMURA NORIAKI
IPC: C07K4/04
Filed: 1992-06-13
Granted: 1998-01-22
Abstract: A prophylactic/therapeutic composition for disseminated intravascular coagulation, chronic respiratory tract infectious disease or chronic bronchitis which comprises WS7622A mono- or disulfate ester or their pharmaceutically acceptable salt. WS7622A is known from European patent application 91110243.2 (EP-A-0 465 895).
Patent DE-69227693-D1 (DE)
Inventor: TODARO GEORGE
IPC: A61P43/00
Filed: 1992-08-24
Granted: 1999-01-07
Abstract: Hybrid cytokines containing four helical regions, each of which is derived from a corresponding alpha-helical region in leukemia inhibitory factor (LIF), granulocyte colony stimulating factor (G-CSF), interleukin-6 (IL-6) or oncostatin-M (OSM) are disclosed. These hybrid cytokines may further contain linking regions also derived from corresponding linking regions in these factors. The hybrid cytokines offer a unique spectrum of activities useful in treating conditions for which the native cytokines are useful or in treating conditions characterized by an excess of the native cytokines.
Patent DE-69227816-D1 (DE)
Inventor: MITCHELL GRANT D
IPC: C09J195/00
Filed: 1992-09-25
Granted: 1999-01-21
Abstract: A pressure sensitive bituminous composition having improved tack and adhesiveness, comprising: (1) from about 50 to about 87% of a bituminous component; from about 1 to about 15% of a thermoplastic block copolymer, M<5>, of the A-B-A type, preferably styrene-butadiene-styrene; (3) from about 1 to about 10% of a block copolymer, M<6>, of the A-B type, preferably styrene-butadiene; and (4) from about 5 to about 50% of a fumed silica. The fumed silica is an active ingredient which absorbs excess oil and improves the tack and adhesiveness of the final composition.
Patent DE-69231340-D1 (DE)
Inventor: PAUL ERIC A
IPC: A61D19/00
Filed: 1992-09-11
Granted: 2000-09-14
Abstract: The invention relates to an egg injection device, including a cylindrical injection needle (32), and a cylindrical punch (31) surrounding the needle (32). A sterilizing fluid passageway (66) is defined by the annular space between the cylindrical injection needle and the surrounding cylindrical punch. A sterilizing fluid entry fitting (67) is provided for adding sterilizing fluid to the passageway (66). Fluid exit openings (70) are provided adjacent to and partially above the lowermost portions of the punch that are most likely to enter an egg (64) during injection. The openings permit a sterilizing fluid to travel from the entry fitting (67), through the passageway (66), and to the exterior surface of the punch (31) so that the sterilizing fluid sterilizes the passageway, the needle, and the portions of the punch that are most likely to enter an egg during injection. <IMAGE>   <IMAGE>
Patent DE-69301356-D1 (DE)
Inventor: DAVIS ADRIAN FRANCIS
IPC: A61K9/06
Filed: 1993-04-02
Granted: 1996-02-29
Abstract: PCT No. PCT/GB93/00692 Sec. 371 Date Oct. 7, 1994 Sec. 102(e) Date Oct. 7, 1994 PCT Filed Apr. 2, 1993 PCT Pub. No. WO93/20799 PCT Pub. Date Oct. 28, 1993Two-component pharmaceutical compositions for topical application to the human or animal body comprising two miscible liquid phases having different lipophilicities and a drug dissolved in at least one liquid phase, each phase comprising at least one topically acceptable non-aqueous and non-volatile solvent.
Patent DE-69303690-D1 (DE)
Inventor: OBER FRANK
IPC: B26D1/20
Filed: 1993-10-28
Granted: 1996-08-22
Abstract: A cutter assembly for cutting sheets of relatively thin material is disclosed. The cutter assembly comprises a base member (18), a pair of support posts (14,16) securely attached to the base member (18), and an elongated guide rail (12) having a first end (12a) and a second end (12b) supported by the support posts (14,16) in laterally spaced relation to the base member (18). A cutting strip (22) is securely retained by the base member (18) for receiving the sheets of material thereon. There is a cutter head (20) slidably mounted on the elongated guide rail (12), and a cutting wheel (64) operatively retained in rotatable relation by the cutter head (20). A spring biasing means (90) biases the cutting wheel (64) toward the cutting strip (22) such that the cutting wheel (64) is received in intimately contracting relation against the cutting strip (22). The cutting wheel (64) moves along the elongated guide rail (12) so as to intimately contact the cutting strip (22) along the length thereof, so as to thereby permit cutting of the sheets of material when they are between the cutting wheel (64) and the cutting strip (22). A spring member (102) is disposed between upper (40) and lower (38) members of the base member (18) so as to camber the upper member (40) to match the bowing of the elongated guide rail (12) that occurs as the cutting wheel (64) moves along the elongated guide rail (12) and therefore along cutting strip (22) to cut the sheets of material. <IMAGE>   <IMAGE>
Patent DE-69333076-D1 (DE)
Inventor: KLINE ELLIS L
IPC: C07K14/435
Filed: 1993-12-17
Granted: 2003-08-07
Abstract: The present invention relates to the diagnosis of multiple sclerosis. More specifically, this invention relates to an assay for detecting antigen(s) associated with multiple sclerosis. The present invention also relates to the generation of hybridomas which produce monoclonal antibodies which are specific for the multiple sclerosis-associated antigens. The present invention's use is in diagnosing multiple sclerosis and in routine follow-up monitoring of multiple sclerosis patients as to disease progression or response to therapy.
Patent DE-69402862-D1 (DE)
Inventor: AUS DER AU HANS-RUDOLF
IPC: B29C41/20
Filed: 1994-06-13
Granted: 1997-05-28
Abstract: For the manufacture of substantially hollow-cylindrical castings (5), especially leading-in insulators for conductors under high voltage, a more or less liquid casting material (50) is introduced into a substantially hollow-cylindrical casting mould (2) that is driven in rotation. Before the introduction of the casting material, the casting mould is heated to a temperature above the gelling temperature of the casting material. The casting mould (2) filled with casting material (50) is driven in rotation until a casting (5) that is substantially set solid has been formed. The casting so formed is then removed from the casting mould. Before the introduction of the casting material into the casting mould, however, a substantially hollow-cylindrical mesh fabric (1) is introduced into the heated casting mould (2) concentrically to the axis of rotation (22) thereof, and only then is the casting material (50) introduced into the casting mould (2).
Patent DE-69403369-D1 (DE)
Inventor: GRIFFITHS BRUCE
IPC: A01D34/00
Filed: 1994-03-25
Granted: 1997-07-03
Abstract: Apparatus for cutting and mulching lawns includes a shallow substantially cylindrical housing (2) having an open bottom and adapted, in use, to have its axis perpendicular to a lawn to be cut; a blade (13), mounted within the housing (2) to rotate about an axis (14) co-axial with that of the housing (2), the blade (13) extending radially from the axis and rotating in a plane near the bottom of the housing (2); a grass exit chute (7) communicating with the inside of the housing (2); a source of rotational power in the form of an electric motor for rotating the blade (13); means for changing the direction of rotation of the blade (13); and means for allowing cut grass within the housing (2) to pass out of the housing (2) into the chute (7) when the blade (13) is rotating in a first direction and to prevent cut grass in the housing (2) from entering the chute (7) when the blade (13) is rotating in a second direction. <IMAGE>
Patent DE-69404495-D1 (DE)
Inventor: GIACOBBE JAMES
IPC: B32B27/12
Filed: 1994-02-16
Granted: 1997-09-04
Abstract: A film or sheet material 95-60 wt. % heteroplastic olefin polymer compsn. (I) and 5-40 wt. % of an ethylene alpha-olefin copolymer (II) of density 0.890-0.940 g/cc in which the alpha-olefin is of formula CH2=CHR (R = 1-8C alkyl). The heteroplastic olefin polymer compsn. (I) comprises 10-50 wt. % propylene polymer (III), 5-20 wt. % semi-crystalline linear copolymer fraction (IV) and 40-80 wt. % xylene-soluble copolymer fraction (V). (III) has an isotactic index greater than 80 and is propylene homopolymer or a copolymer contg. over 80 wt. % propylene with ethylene and/or a 4-10C alpha-olefin. (IV) has a crystallinity of 20-60 % and is insoluble in xylene at room temp. (IV) is a copolymer of ethylene and propylene contg. over 55 wt. % ethylene, or a copolymer of ethylene, propylene and 1-10 wt. % 4-10C alpha-olefin in which the combined content of ethylene and 4-10C alpha-olefin is over 55 wt. %, as a copolymer of ethylene and a 4-10C alpha olefin contg. over 55 wt. % 4-10C alpha-olefin. (V) has a intrinsic viscosity of 1.5-4.0 dl/g and is a copolymer of ethylene and propylene contg. 20-40 wt. % ethylene at a copolymer of ethylene, propylene and 1-10 wt. % 4-10C alpha-olefin in which the combined content of ethylene and 4-10C alpha-olefin is 20-40 wt. % or a copolymer of ethylene, 4-10C alpha-olefin and opt. 0.5-10 wt. %, diene, in which the 4-10C alpha-olefin content is 20-40 wt. %. The wt. ratio of (IV):(V) is less than 0.4:1. (I) is prepd. by polymerisation in at least 2 stages.
Patent DE-69405570-D1 (DE)
Inventor: DE BRABANDER-VAN DEN BERG ELLE
IPC: C08F8/30
Filed: 1994-07-04
Granted: 1997-10-16
Abstract: The invention relates to a process for the preparation of a dendritic macromolecule, wherein an amount of a core molecule comprising at least one functional group is dissolved in a solvent, after which alternatingly an addition reaction and a hydrogenation reaction are carried out, during the addition reaction vinyl cyanide units being added to the solution which react with the functional groups in such a manner that a dendritic macromolecule with terminal cyanide groups is formed, and during the hydrogenation reaction the cyanide groups being reduced in solution by means of hydrogen and a suitable catalyst in such a manner that functional amine groups are formed, wherein the solvent in which the hydrogenation reaction takes place is an alcohol which contains an amount of ammonia, the molar ratio between the amount of ammonia and the number of cyanide groups being higher than 0.8.
Patent DE-69418981-D1 (DE)
Inventor: VOELKENING HEINZ
IPC: B66B29/06
Filed: 1994-12-20
Granted: 1999-07-15
Abstract: A body, has a width, a length, grooves extending widthwise across a top surface, a bottom surface, and ribs, extending between said bottom and top surfaces. A rear support, extends out from the body on a surface opposite the grooved top surface. A comb attachment surface, is provided where the body, the rear support, and the comb attachment surface define a lengthwise cross-sectional profile which extends uniformly in a widthwise direction.
Patent DE-69427950-D1 (DE)
Inventor: YANAGIHARA NAOFUMI
IPC: H04N5/783
Filed: 1994-10-21
Granted: 2001-09-20
Abstract: A digital video tape recorder (3), which operates to receive an advanced television (ATV) signal to be recorded, provides a portion such as a low-band coefficient of an intracoded frame of the ATV signal as variable-speed data, and records the digital video data and the variable-speed data in a main area (A1) and a marginal area (A2), respectively, of successive tracks on a record medium in which the marginal area is located on each track at a position which is reproducible in a fast-speed reproducing mode. The digital video tape recorder reproduces the recorded data in the fast-speed reproducing mode by reproducing the portion of the signal stored from the marginal area of each track which is located at specific reproducible areas. <IMAGE>
Patent DE-69428619-D1 (DE)
Inventor: BRADSHAW JOHN JAMES
IPC: B28C5/16
Filed: 1994-02-28
Granted: 2001-11-22
Abstract: The invention provides apparatus for use in the preparation of gypsum products such as plasterboard from foamed gypsum plaster slurry. The apparatus comprises a first mixing chamber 10 containing a high speed rotor 14 and inlets for 18, 19 for gypsum plaster and water. The initial dispersion of gypsum plaster and water foamed in the first chamber passes directly and continuously into a second chamber 25 containing a low speed rotor 29. Preformed foam is introduced into the second chamber through an inlet 33, and the foamed slurry product leaves the second chamber through an outlet 34, to be formed into plasterboard. A method of making gypsum products from foamed gypsum plaster slurry is also disclosed. <IMAGE>
Patent DE-69428912-D1 (DE)
Inventor: SCOTT DAVID
IPC: C07C17/21
Filed: 1994-12-07
Granted: 2001-12-06
Abstract: A process for the production of pentafluoroethane which comprises the steps (i) producing a composition comprising a compound of formula C2HClxFy in which x=1,2 or 3 and y=2,3 or 4 provided that x+y is 5, contaminated with a compound of formula C2Clx+1Fy, (ii) separating the compound of formula C2HClxFy from the compound of formula C2Clx+1Fy, and (iii) contacting the compound of formula C2HClxFy with hydrogen fluoride in the presence of a fluorination catalyst to produce pentafluoroethane is disclosed.
Patent DE-69430801-D1 (DE)
Inventor: MCEWAN E
IPC: H04B1/7163
Filed: 1994-04-08
Granted: 2002-07-18
Abstract: An ultra-wideband (UWB) receiver utilizes a strobed input line with a sampler connected to an amplifier. In a differential configuration, +/-UWB inputs are connected to separate antennas or to two halves of a dipole antenna. The two input lines include samplers which are commonly strobed by a gating pulse with a very low duty cycle. In a single ended configuration, only a single strobed input line and sampler is utilized. The samplers integrate, or average, up to 10,000 pulses to achieve high sensitivity and good rejection of uncorrelated signals.
Patent DE-69430911-D1 (DE)
Inventor: BRITZKE W
IPC: B24B3/26
Filed: 1994-11-10
Granted: 2002-08-08
Abstract: The present invention provides a method of surface decarburizing a cemented carbide cutting tool. The tool is placed in a protective environment. The tool is heated to an elevated temperature of between 600-1100 degrees C while in the protective environment for a period of 15-120 minutes. In another aspect of the invention, a drill is provided having a drill body (13) which has a cutting tip, an axis of symmetry, and a plurality of flutes (15), wherein the flutes (15) have a rake surface (17) at the cutting tip. The cutting tip comprises a plurality of side blade between the flutes (15) and joined at a web. A plurality of flank surfaces (27) extend from an outer diameter of the cutting tip to the axis of symmetry and a plurality of primary cutting edges (20) are present at the intersection of the flank surfaces (27) with the rake surfaces (17). The primary cutting edges (20) include either an angular or radius surface (21) or a combination thereof extending from the flank surfaces (27) to the rake surfaces (17).
Patent DE-69434010-D1 (DE)
Inventor: HOLTON ROBERT A
IPC: C07D305/14
Filed: 1994-01-28
Granted: 2004-10-21
Abstract: Taxane derivatives having alternative C7 substituents.
Patent DE-69518415-D1 (DE)
Inventor: NISHIDA TADASHI
IPC: C12P21/08
Filed: 1995-03-22
Granted: 2000-09-21
Abstract: A remedy for rheumatoid arhthritis containing a monoclonal antibody recognizing specifically an extracellular region of human VLA-2 as the active ingredient, preferably one containing a monoclonal antibody recognizing specifically an extacellular region of the alpha  chain of human VLA-2. The remedy can suppress swelling due to arthritis caused by rheumatoid arthritis and is lowly toxic, thus being efficacious in treating rheumatoid arthritis.
Patent DE-69521904-D1 (DE)
Inventor: ZERGENYI JANOS
IPC: A61K31/41
Filed: 1995-10-23
Granted: 2001-08-30
Abstract: The invention relates to a process for the preparation of N-protected 4-methyl-2'--(5H-tetrazolyl)biphenyl of formula (I), in which R is a tetrazole protective group, wherein a compound of formula (II), in which R is a tetrazole protective group, is reacted with a compound of formula (III') in which Hal is halogen, in the presence of a transition metal catalyst, to novel compounds of formula (I) and their use, and to novel intermediates.
Patent DE-69523063-D1 (DE)
Inventor: JASICA STANISLAW
IPC: B65D90/02
Filed: 1995-10-30
Granted: 2001-11-08
Abstract: PCT No. PCT/NZ95/00111 Sec. 371 Date Jul. 9, 1997 Sec. 102(e) Date Jul. 9, 1997 PCT Filed Oct. 30, 1995 PCT Pub. No. WO96/14256 PCT Pub. Date May 17, 1996Packaging particularly for bulk materials can include container flexible container which can be contained and suspended within a lifting cradle (11) and about which lifting cradle (11) and the inner container an outer container can be positioned. The lifting cradle (11) has an outlet (14) so as to coincide with the outlet in the base of the inner container and to enable the discharge of materials from the inner container without the need to remove the lifting cradle (11). Lifting straps (15) can provide a loose connection with connectors from the upper portion of the inner container so that when suspended the weight of the inner container and its contents is taken by the lifting cradle (11) and not by the inner container.
Patent DE-69528709-D1 (DE)
Inventor: NOREEN LARS
IPC: B01D53/81
Filed: 1995-06-21
Granted: 2002-12-05
Abstract: A method of cleaning ventilation air that is contaminated with at least two organic solvents, wherein the ventilation air is caused to pass through fluidized beds that contain material capable of adsorbing the solvents and thereafter capable of releasing the organic substances present in the solvents by desorption. The ventilation air is caused to pass first through at least one first fluidized bed (2, 3) that contains an adsorbent material particularly suited for adsorption of one of the organic substances, and is then passed through at least one second fluidized bed (4, 5) that contains an adsorbent material particularly suited for adsorption of the other of said organic substances. The adsorbents are then tapped off separately from the first and the second beds for regeneration of the adsorbents by desorption of the organic substances, whereafter the absorbents are returned to their respective beds. The invention also relates to an arrangement for use when carrying out the method.
Patent DE-69533112-D1 (DE)
Inventor: BOMBARDELLI EZIO
IPC: A61K31/335
Filed: 1995-10-10
Granted: 2004-07-08
Abstract: The invention relates to methods for preventing, inhibiting, or suppressing tumors by administering to a person in need of such treatment a therapeutically effective amount of one or more flavanolignanes, such as silymarin, silybin, silidianin, silicristin, dehydrosilybin, mixtures thereof, or extracts thereof as an antiproliferative. The invention further relates to the antitumor pharmaceutical composition includes a therapeutically effective amount of the flavanolignane selected from the group of silymarin, silybin, silidianin, silicristin, dehydrosilybin, and mixtures thereof, in combination with a different antitumor agent. In another embodiment, the pharmaceutical composition includes a therapeutically effective amount of a flavanolignane selected from the group of silidianin, silicristin, and mixtures thereof, with a pharmaceutically acceptable carrier or excipient. The compositions and method may be prepared or administered with different antitumoral agents for concurrent or sequential use for treating tumors, such as those typically found in the uterus, ovary, and breast.
Patent DE-69534878-D1 (DE)
Inventor: WANG QING
IPC: C12N15/09
Filed: 1995-11-03
Granted: 2006-05-11
Abstract: The present invention is directed to novel replication-deficient adenoviral vectors characterized in that they harbor at least two lethal early region gene deletions (E1 and E4) that normally transcribe adenoviral early proteins. These novel recombinant vectors find particular use in human gene therapy treatment whereby the vectors additionally carry a transgene or therapeutic gene that replaces the E1 or E4 regions. The present invention is further directed to novel packaging cell lines that are transformed at a minimum with the adenoviral E1 and E4 gene regions and function to propagate the above novel replication-deficient adenoviral vectors.
Patent DE-69535689-D1 (DE)
Inventor: REUSCH ROSETTA N
IPC: B01D61/00
Filed: 1995-09-26
Granted: 2008-03-06
Abstract: Lipid bilayers which incorporate poly-3-hydroxybutyrate/polyphosphate ion channels. The ion channels are preferably purified polyhydroxybutyrate polyphosphate complexes extracted from organisms or prepared from the individual constituents which have been size selected. The bilayers are useful for testing the affect of various molecules and ions on the channel which correlates to the in vivo result. The bilayers are useful for transporting the channels into cells or other bilayers.
Patent DE-69602511-D1 (DE)
Inventor: DREXLER JOHANNES HERMAN
IPC: B60N2/28
Filed: 1996-12-03
Granted: 1999-06-24
Abstract: An infant safety seat of the type, comprising a bucket seat body (1) having a supporting bottom and a pivotable carrying handle and provided with attachment points for the hip belt portion and the shoulder belt portion respectively of a threepoints-safety belt (8). Between the support bottom surface and the seat surface thereabove there is a transverse through belt receiving space adjacent the front side of the bucket seat body (1), said space being delimited at the front side by a transverse and upstanding belt holding surface, that is accessible for a belt from an end of the bucket seat body (1). <IMAGE>
Patent DE-69602840-D1 (DE)
Inventor: MILLS NED
IPC: B62M9/08
Filed: 1996-07-02
Granted: 1999-07-15
Abstract: A continuously variable transmission utilizes a variable eccentric assembly arranged about a central transmission axis. A plurality of input and output vanes are operably interconnected to an orbiter and are sequentially engaged by input and output ratchets that circumscribe them. Positive driving connections are provided between the ratchets and vanes by outer toothed pawls yieldably mounted at the outer ends of the respective vanes. A secondary multiplier transmission can be arranged coaxially with the vanes, which are rotatably supported about the central shaft of the transmission.
Patent DE-69604738-D1 (DE)
Inventor: DIN SHAHID
IPC: A61J1/16
Filed: 1996-02-01
Granted: 1999-11-25
Abstract: A system and a method are provided to effect solution exchange particularly for a patient requiring peritoneal dialysis. The system includes a device (1) that is portable and particularly adaptable for patients requiring a night time exchange or an additional exchange. The device (1) includes an operator-touch control panel (10) operatively connected to a pouch (26) with an incorporated heater (12). The pouch (26) holds a solution bag (18) and may be selectively opened and closed by a cover (28). A drain tray (30) holds a drain bag (20) and has a scale (14) incorporated therein. The pouch (26) is connected to the control panel (10) by an upper arm (38), and the drain tray (30) is connected to the control panel (10) by a lower arm (42). The device (1) may be collapsed by releasing the upper arm (38) and the lower arm (42) such that the system (1) lays in a substantially flat arrangement when not in use.
Patent DE-69615607-D1 (DE)
Inventor: OGURA MOTOHIRO
IPC: G03G7/00
Filed: 1996-05-14
Granted: 2001-11-08
Abstract: A transfer paper for color electrophotography has an intermediate layer and transfer layers respectively provided on the surface side and back side of the intermediate layer. The intermediate layer has a surface resistivity which is higher than the surface resistivity of the transfer layers. The transfer paper has a basis weight of from 100 g/m<2> to 160 g/m<2>. The surface of the transfer paper has a Bekk smoothness within the range of from 100 seconds to 200 seconds. <IMAGE>