baber/WOPTO huggingface dataset:
Patent CA-3071337-A1 (CA)
Title: Igg fc variants for veterinary use
Inventor: ZHAN HANGJUN
IPC: A61K38/17
Filed: 2018-08-15
Abstract: Provided are various embodiments relating to variant IgG Fc polypeptides of companion animals having increased Protein A binding for ease of purification, decreased C1q binding for reduced complement-mediated immune responses, decreased CD16 binding (e.g. , for reduced antibody-dependent cellular cytotoxicity (ADCC) induction, increased stability, and/or the ability to form heterodimeric proteins. In addition, various embodiments relating to antibodies and fusion proteins comprising such variant IgG Fc polypeptides are provided. Also provided are various embodiments relating to contiguous polypeptides comprising one or more variant GLP 1 polypeptide(s) having improved serum half-life. Further provided are various embodiments relating to contiguous polypeptides or heterodimeric polypeptides comprising a GLP 1 polypeptide and a glucagon polypeptide as a dual GLP 1 receptor and glucagon receptor agonist. In various embodiments, such polypeptides may be used to treat, for example, diabetes, obesity, or related indications, in companion animals, such as canines, felines, and equines.
Patent CA-3071616-A1 (CA)
Inventor: MURRAY JAMES SCOTT
IPC: G07C9/00
Filed: 2018-07-31
Abstract: Un actionneur de barrière mobile comprend un moteur, des circuits de communication configurés pour recevoir un signal de commande et pour communiquer avec un verrou de porte associé à une porte de passage, et un dispositif de commande. Le dispositif de commande est configuré pour authentifier le signal de commande, l'authentification du signal de commande consistant à associer le signal à un premier niveau d'accès ou à un second niveau d'accès. Le dispositif de commande est en outre configuré pour communiquer avec le verrou de porte par l'intermédiaire des circuits de communication de façon à permettre l'ouverture de la porte de passage en réponse à l'association du signal de commande au premier niveau d'accès et pour empêcher l'ouverture de la porte de passage en réponse à l'association du signal de commande au second niveau d'accès. Le dispositif de commande est configuré pour amener le moteur à ouvrir la barrière mobile indépendamment de l'association du signal de commande au premier niveau d'accès ou au second niveau d'accès.
Patent CA-3071929-A1 (CA)
Inventor: HASSEL TAMRYN JO
IPC: C12Q1/24
Filed: 2018-08-08
Abstract: The present invention provides a method for detecting a microorganism in a sample, the method comprising : a) filtering a sample through a filter to entrap any microorganisms present in the sample;  b) treating the filter to release genomic material or DNA  from the entrapped microorganisms; c) amplifying the genomic material or DNA  released from the entrapped microorganisms; and d) identifying specific regions of the genomic material or DNA to determine the presence, identify the species or quantify the approximate number of any entrapped microorganisms.
Patent CA-3072582-A1 (CA)
Inventor: WOOD MATTHEW
IPC: B65D19/00
Filed: 2018-08-14
Abstract: Cette invention concerne une palette, comprenant un plateau supérieur qui comprend une surface de support de produit et une surface inférieure opposée, et la surface de support de produit comprenant une paire de zones de réception de patte de support de palette. Une paire de pattes de support de palette est disposée sur la surface inférieure du plateau supérieur et alignée avec les zones de réception de patte de support de palette. Chaque patte de support de palette comprend une section de patte centrale ayant une première extrémité adjacente à la surface inférieure du plateau supérieur et une seconde extrémité opposée à la première extrémité, et une paire d'extensions de patte s'étendant vers l'extérieur à partir de la seconde extrémité de la section de patte centrale. Une surface inférieure de la section de patte centrale et la paire d'extensions de patte sont configurées pour venir en prise avec une des zones de réception de patte de support de palette d'une palette identique lorsqu'elle est empilée sur celle-ci.
Patent CA-3075781-A1 (CA)
Inventor: ISAACSON RAY
IPC: B01L3/00
Filed: 2018-09-18
Abstract: Des aspects de l'invention concernent des dispositifs de réalité augmentée pour générer une scène composite comprenant un environnement de test du monde réel et une superposition de réalité augmentée représentant visuellement une zone de test de l'environnement. Certains dispositifs peuvent comprendre des dispositifs d'affichage portables pour afficher une superposition à un utilisateur, et d'autres dispositifs peuvent comprendre des projecteurs pour l'éclairage de l'environnement de test avec la superposition.
Patent CA-3075989-A1 (CA)
Inventor: PARAK MAHDI
IPC: E21B41/00
Filed: 2017-11-13
Abstract: Dans le cadre de la présente invention ,la production de fluide peut être simulée en utilisant un modèle de réservoir et un modèle de tubage. Par exemple, des données de pression et des données de saturation peuvent être reçues d'un modèle de réservoir qui simule un réservoir d'hydrocarbures dans une formation souterraine. Un modèle de tube peut être généré en réalisant une analyse nodale en utilisant les données de pression et les données de saturation. Un résultat d'essai de puits peut être reçu qui indique une quantité de fluide produite par le puits de forage à un moment particulier. Un modèle de tubage réglé peut être généré en ajustant le modèle de tubage de telle sorte qu'une estimation de modèle de tubage de la quantité de fluide produite par le puits de forage au moment particulier corresponde au résultat d'essai de puits. Une quantité estimée de fluide produite par le puits de forage peut ensuite être déterminée en utilisant le modèle de tubage réglé. La quantité estimée de fluide produite par le puits de forage peut être utilisée pour l'attribution de production ou la commande d'un outil de puits.
Patent CA-3078576-A1 (CA)
Title: Hydration and air cooling system
Inventor: JAEGER EDUARD ALBERT
IPC: A62B9/04
Filed: 2017-11-17
Abstract: A magnetic quick connect for a fluid delivery system includes a male coupling member and a female coupling member.  The male coupling member defines a first outer fluid communication path and includes a first magnetic material. A first inner member is disposed within the first outer fluid communication path and defines a first inner communication path. The female coupling member defines a second outer fluid communication path and includes a second magnetic material. A second inner member is disposed within the second outer fluid communication path and defines a second inner communication path. The male and female coupling members are detachably held together by an attractive force between the first and second magnetic materials such that the first and second outer communication paths are held in fluid communication, and the first and second inner communication paths are held in fluid communication.
Patent CA-3079254-A1 (CA)
Inventor: SAMAKI SOUFIANE
IPC: A62B23/02
Filed: 2020-05-20
Abstract: L'invention est un masque qu'on met au dessus du visage et qui permet de purifier l'air ambiant de tous type de microorganisme avec de la lumière sous forme de laser des rayons ultraviolet ou de la lumière pulsée. L'invention a pour but de trouver une solution au problème de pénurie des masques de protection contre les virus et les microorganismes. Les masques utilisés en ce moment par les professionnels de la santé sont la plupart non réutilisables et constitue aussi une source de propagation des virus. L'invention résout les deux problèmes en utilisant un filtre tueur de microorganisme en utilisant des barrières de lumières ce qui rend le masque réutilisable et empêche la propagation des virus.
Patent CA-3079731-A1 (CA)
Title: System and method for integrated use of field sensors for dynamic management of irrigation and crop inputs
Inventor: LARUE JACOB L
IPC: G06F7/70
Filed: 2018-10-26
Abstract: The present invention provides a system for combining the use of near real-time and/or realtime data acquired from an array of single purpose or integrated sensors mounted on a mechanized irrigation machine. According to a preferred embodiment, the integrated sensor of the present invention preferably provides for the collection of a variety data. The number of integrated sensors mounted on a mechanized irrigation machine may preferably be determined based on a detected number of management zones and/or a detected location. According to a further preferred embodiment, integrated sensor(s) of the present invention may preferably provide specific data of current field conditions and send the detected data to a central control to apply the appropriate analytics to determine crop health, crop water use, crop water stress index and a variety of crop indices.
Patent CA-3080301-A1 (CA)
Title: Anonymity system for goods delivery
Inventor: BITAULD DAVID
IPC: H04W12/02
Filed: 2018-10-26
Abstract: According to an example aspect of the present invention, there is provided a method,comprising:defining a delivery identifier for delivery of goods from a sender to a receiver, defining a relay for the delivery of goods, selecting one or more sender couriers to send the goods to the relay and/or selecting one or more receiver couriers to receive the goods from the relay, generating for the goods delivery a smart contract comprising cryptographic tokens for confirming delivery, wherein the smart contract is a computerized transaction protocol and is configured to validate delivery of the goods on the basis of tokens from the couriers, providing the smart contract for the goods delivery to the distributed network, and providing the cryptographic tokens, the delivery identifier and an identifier of the relay to the selected one or more couriers.
Patent CA-3080756-A1 (CA)
Title: Method of treating water containing arsenic and manganese
Inventor: JASIM SAAD
IPC: C02F1/58
Filed: 2020-05-08
Abstract: A method of treating water containing dissolved arsenic and manganese. Ozone is injected into the water at a concentration in the range of 0.2 to 1.0 mg/L, oxidizing As(l II) to As(V) and Mn(II) to Mn(IV). Ferric chloride coagulant is added to the ozonated water, coagulating the As(V) and the Mn(IV). The water is then filtered with a first filter medium selected for removal of the Mn(IV) followed by a second filter medium selected for removal of As(V). This removes the coagulate to produce treated water. The method removes arsenic and manganese to low levels acceptable for drinking water, using low concentrations of ozone as an oxidant. An advantage is that the ozone system can have a relatively small footprint, and use less energy, an important factor for climate change. Further, a quenching agent for removal of residual ozone is not required.
Patent CA-3087610-A1 (CA)
Inventor: ZHANG YI
IPC: H04L9/08
Filed: 2015-07-21
Abstract: Abstract Disclosed is an online transaction method, device and system: a buyer's device generates and delivers order information to a commodity server; the buyer's bank server generates a to-be-validated Bank Credit Certificate and acquires buyer's payment verification information from the buyer's device, and validates the Bank Credit Certificate for delivering the validated Bank Credit Certificate to a seller's bank server; the seller's bank server delivers a notification for receiving the Bank Credit Certificate to the commodity server after updating the validated the Bank Credit Certificate to a received status; the commodity server delivers the order information to a transaction intermediation server for arranging commodity delivery and receipt notification; and the seller's bank server delivers the receipt notification to the buyer's bank server for money transfer. The present invention provides a method to reduce the risk to the funds and increase the security of the transaction information. Date Recue/Date Received 2021-05-07
Patent CA-3091594-A1 (CA)
Inventor: SIMON ALEXANDRE
IPC: B66C23/80
Filed: 2020-08-31
Abstract: Un essieu oscillant pour un engin de levage, l'essieu comprenant des vérins gauche et droit, un circuit hydraulique reliant entre elles les chambres des vérins, une électrovanne sur une branche du circuit reliée à la chambre du vérin gauche, une électrovanne sur une branche du circuit reliée à la chambre du vérin droit et des moyens de contrôle. Chacune des électrovannes est adaptée pour être positionnée dans une position ouverte où le fluide peut circuler librement et une position fermée où le fluide est emprisonné dans la chambre du vérin correspondant. Chacune des chambres comprend un capteur de pression. Les moyens de contrôle sont adaptés pour détecter une pression dans l'une des chambres supérieure à un premier seuil et/ou un différentiel entre les pressions dans chacune des chambres supérieur à un second seuil afin de détecter un blocage en position fermée d'une électrovanne et de déclencher une procédure de sécurisation.
Patent CA-3091857-A1 (CA)
Inventor: CAFFARO CAROLINA E
IPC: C07K14/54
Filed: 2019-02-26
Abstract: L'invention concerne des conjugués d'interleukine (IL) 15 et leur utilisation dans le traitement d'une ou de plusieurs indications. Des compositions pharmaceutiques et des kits comprenant un ou plusieurs des conjugués d'IL-15 sont en outre décrits.
Patent CA-3098146-A1 (CA)
Title: Improved methods for inducing tissue regeneration and senolysis in mammalian cells
Inventor: WEST MICHAE D
IPC: A61K31/192
Filed: 2019-04-23
Abstract: Aspects of the present invention include compositions and methods for discovering novel compositions and applying said compositions in treating medical conditions including aging, degenerative disease, wound treatment, and cancer through the modulation of molecular pathways regulating regeneration and senolysis by means of altering the embryonic-fetal and prenatal/postnatal transitional states of mammalian cells.
Patent CA-3100734-A1 (CA)
Inventor: HOUSEY GERARD M
IPC: A61P5/50
Filed: 2019-05-17
Abstract: Provided herein are methods for modulating follistatin, such as inhibiting follistatin, suppressing the production of follistatin, reducing the level of follistatin, inhibiting the function of follistatin, or a combination thereof. The method can include administration of a compound that acts to modulate follistatin. In one embodiment, the compound is administered to a patient having or at risk or having a disease or condition selected from diabetes, pre-diabetes, metabolic syndrome, insulin resistance, dementia, and obesity, and optionally the disease or condition is prevented, treated, ameliorated, or a combination thereof.
Patent CA-3101041-A1 (CA)
Inventor: FRASER DAVID ALAN
IPC: A61P1/00
Filed: 2019-05-22
Abstract: La présente invention concerne un composé destiné à être utilisé en tant qu'activateur de la production de GLP-1 par les cellules entéroendocrines, améliorant la régulation glycémique, et le traitement d'une maladie intestinale inflammatoire, le composé étant un acide gras insaturé structurellement modifié avec un substituant alpha, seul ou en association avec un ou plusieurs agents thérapeutiques supplémentaires.
Patent CA-3102857-A1 (CA)
Inventor: GALIATSATOS VASSILIOS
IPC: C08J9/12
Filed: 2019-06-14
Abstract: Foamed reactor made thermoplastic polyolefins (rTPOs), and articles made therefrom., are described. The compositions have an rTPO combined with a foaming agent. Tire foaming agent can be a physical blowing agent and/or a chemical foaming agent, and may include optional nucleating agents. Some compositions utilize a masterbatch having one or more chemical foaming agents to foam the rTPOs, The rTPOs have a large melt flow rate range and flexural modulus range that translate into a broad scope of potential applications and foamed architecture. This allows the combination of rTPOs and foaming agents to be fine-tuned for selected foaming application.
Patent CA-3103481-A1 (CA)
Inventor: BURNETT ROBERT
IPC: A43B13/04
Filed: 2020-12-21
Abstract: ABSTRACT A footwear item that includes a rubber sole, and an upper portion attached to the rubber sole. The upper portion is made from rubber. The rubber sole includes a layer of aerogel thermal retention material for an interior section of the footwear item. The layer of aerogel thermal retention material covers the interior portion of the rubber sole along with a front part of the footwear item such that the layer of aerogel thermal retention material contacts a sole of a foot of a wearer while also surrounding the toes of the wearer. In certain embodiments, the layer of aerogel thermal retention material has a thickness ranging from 0.1 millimeters to 20 millimeters. Date Recue/Date Received 2020-1 2-2 1
Patent CA-3105098-A1 (CA)
Title: Vtt ayant une configuration de poignee pour un passager
Inventor: RIPLEY RICHARD D
IPC: B60R9/00
Filed: 2009-02-03
Abstract: Un véhicule comprend un châssis; un siège de type selle installé sur le châssis pour un conducteur ou une conductrice; un montage daccessoire, supporté par le châssis, qui comprend une surface de support ayant une ouverture formée dans ce dernier; et un conteneur configuré pour être installé sur le montage daccessoire. Le conteneur a une protubérance dimensionnée et configurée pour être reçue à lintérieur de louverture de la surface de support.
Patent CA-3105834-A1 (CA)
Inventor: WILLIAMS MARK
IPC: A61K31/44
Filed: 2019-07-03
Abstract: The current application relates to the use of emoxypine or a glutamate 2b receptor (Glut2B) antagonist for the treatment or prophylaxis of colitis or inflammatory bowel disease (IBD) in a subject. The glut2B antagonist or emoxypine can also be combined with other drugs such as anti-inflammatory drugs, immune system suppressors, antibiotics, anti-diarrheas, pain relievers, iron supplements, vitamin B12, or calcium/vitamin D supplements.
Patent CA-3106088-A1 (CA)
Title: Method and apparatus for sealing a side pocket mandrel
Inventor: HANSEN HENNING
IPC: E21B23/03
Filed: 2019-06-19
Abstract: A method for sealing a side pocket mandrel and hydraulic tube includes moving a sealant dispenser into a pocket of the side pocket mandrel from within a well tubing. The sealant dispenser has an upper seal and a lower seal spaced apart therefrom; the seals are sealingly engaged with the pocket. A space between the upper seal and the lower seal is in fluid communication with at least one port in the pocket. A curable sealant is moved from the sealant dispenser into the pocket and into the tube. Either the sealant is allowed to cure or the sealant dispenser is unlatched from a running tool used to move the sealant dispenser into the pocket.
Patent CA-3106595-A1 (CA)
Inventor: HEYWOOD JONATHAN
IPC: F16L21/06
Filed: 2019-09-18
Abstract: A device (2) for holding a tubular component (4) on a vehicle is proposed, the device (2) com-prising a bracket (6), two strap parts (8, 10) and at least two trunnions (14), wherein both strap parts (8, 10) on one end comprise a loop (16, 28) and on an opposed end a connection surface (32, 34), wherein the bracket (6) comprises at least one receiving opening (58) for each trunnion (14) to hold the respective trunnion (14) in the at least one receiving opening (58), wherein each loop (16, 28) is dimensioned to allow one of the trunnions (14) to extend through the loop (16, 28) when being placed in the respective at least one receiving opening (58) of the bracket (6), wherein the connection surfaces (32, 34) are shaped so as to be connectable to each other and to form a closed strap and wherein the bracket (6) comprises a holding device (12) for attaching the bracket (6) to the vehicle.
Patent CA-3110089-A1 (CA)
Title: Methods and compositions for adoptive t cell therapy incorporating induced notch signaling
Inventor: RIDDELL STANLEY R
IPC: C12N5/0783
Filed: 2019-08-28
Abstract: The disclosure provides in some aspect methods and compositions related to culturing and engineering T cells that maintain less differentiated state. The T cells are cultured in conditions that induce Notch signaling. The resulting T cells exhibit maintenance of a less differentiated state for prolonged periods and have reduced susceptibility to exhaustion. Also provided are the cells produced by the methods, as well as related compositions and methods of use for adoptive therapy.
Patent CA-3110119-A1 (CA)
Inventor: ASAKAWA YUICHIRO
IPC: H01M4/137
Filed: 2019-09-06
Abstract: Described are polymers, polymer binders, hydrogel polymer binders, hydrogel polymer binder compositions comprising them, electrode materials comprising them, their methods of production and their use in electrochemical cells, for instance, in silicon-based electrochemical cells.
Patent CA-3111549-A1 (CA)
Inventor: VILLARINO ERNEST R
IPC: B25D1/06
Filed: 2021-03-09
Abstract: A striking tool includes an elongated handle having a first end and a second end. The head is attached to or formed integrally with the first end of the handle and defines a striking portion, a claw portion, and a body portion therebetween. The striking tool may have slots, notches, and/or cavities configured to engage fasteners or other objects for applying torsion thereto.  A  striking member may be removably attached to the striking portion of the head, which may define a nail puller. Attachments, such as an axe head, may be removably attachable to the head of the striking tool.
Patent CA-3112871-A1 (CA)
Inventor: MURAKAMI YOSHINOBU
IPC: G21K5/08
Filed: 2021-03-22
Abstract: Provided is a target device (100) capable of improving the cooling performance of a cooling mechanism (4). According to the target device (100), a target accommodation unit (3) has a first region (El) that accommodates a target liquid (101) and a second region (E2) that receives a boiled gas-liquid mixture (102) of the target liquid (101). In contrast, the cooling mechanism (4) includes a first cooling unit (30A) that cools at least the first region (El) and a second cooling unit (30B) that cools at least the second region (E2). Moreover, the second cooling unit (30B) forms a flow (flow F2 in FIG. 2) of the refrigerant from top to bottom in the second region (E2). The cooling performance obtained by the refrigerant flowing from top to bottom can be made higher than the cooling performance in a case where the refrigerant used in the first cooling unit (30A) is used as it is.
Patent CA-3113428-A1 (CA)
Title: System for monitoring concrete pumping systems
Inventor: VASQUEZ JULIO
IPC: F04B15/02
Filed: 2019-09-23
Abstract: A system for monitoring a dual cylinder concrete pumping apparatus and a transition valve operated by an actuator. The system including position sensors to detect the position of pistons in the dual cylinders and the actuator. Additional sensors can monitor various aspects of the concrete pumping apparatus. A processor receives information from the sensors and transmits data to a monitor. When sensor data is outside of predetermined parameters, the processor sends an alert notice and a performance snapshot of the system to the monitor.
Patent CA-3114691-A1 (CA)
Title: Compositions et methodes pour le traitement d'un dysfonctionnement des muscles lisses
Inventor: MELMAN ARNOLD
IPC: A61P11/06
Filed: 2019-11-14
Abstract: La présente invention concerne des compositions et des procédés pour traiter des maladies et des affections liées à un dysfonctionnement des muscles lisses, ou pour faire régresser les symptômes de celles-ci, comprenant une thérapie génique, un ou plusieurs polynucléotides codant pour une ou plusieurs sous-unités du canal Maxi-K, ou des mutants, des variants, des fragments fonctionnels ou des dérivés de ceux-ci (par exemple, des fusions et des chimères) étant administrés à un sujet qui en a besoin, et l'administration des polypeptides conduisant à l'expression de canaux Maxi-K fonctionnels dans le muscle lisse ciblé. Selon certains aspects, la composition de l'invention comprend des vecteurs plasmidiques contenant au moins un acide nucléique codant pour un peptide de canal Maxi-K. L'invention concerne également des compositions pharmaceutiques, des articles ou la fabrication, et des kits.