baber/WOPTO huggingface dataset:
Patent EP-2899364-A2 (EP)
Inventor: MCNAMEE STEPHEN
IPC: E21B43/04
Filed: 2015-01-22
Abstract: A gravel pack assembly (100) for a borehole has first and second joints (102a-b) and a foil (150). The basepipes of the joints connect end-to-end, and both of the basepipes having filters (140a-b) for filtering fluid passage from a borehole into bores of the basepipes. Transport tubes are disposed along the first and second joint, and a jumper tube expands across the connected ends of the basepipes and connects the transport tubes together. The foil encloses an area across the connected ends. The foil has an external surface defining an annulus thereabout with the borehole. The foil has end rings abutting the filters of the joints. At least a section of the foil leaks fluid from the borehole to the area enclosed by the foil, and at least a filter portion of the assembly filters the leaked fluid from the area to at least one of the first and second bores.
Patent EP-2902335-A2 (EP)
Inventor: CAMERON DAVID
IPC: B65D33/25
Filed: 2009-04-23
Abstract: A reclosable package comprises a first panel (12) including a first side section and a second side section and a second panel (14) including a first side section and a second side section. The first panel (12) opposes the second panel (14) and is joined to the second panel (14) along the first and second side sections. A bottom extends between the first and second side sections of the first and second panels (12, 14) with the first and second panels joined to each other. A mouth is disposed opposite the bottom and extends between the first and second side sections of the first and second panels (12, 14). A closure member extends along the mouth, the closure member including a first fin (280a) and a second fin (280b) each having sealing ribs (287) configured to form a seal joining the first fin (280a) to the first panel (12) and the second fin (280b) to the second panel (14), respectively. A sealing member has a first end attached to the first fin (280a) and a second end attached to the second panel (14).
Patent EP-2902786-A2 (EP)
Inventor: YOSHIMIZU MIWAKO
IPC: G01N33/543
Filed: 2009-06-30
Abstract: The present application discloses a binding assay strip comprising a porous solid phase for binding assay in which at least one surfactant has been incorporated prior to addition of a test sample, the at least one surfactant being selected from the group consisting of: n-heptyl-β-D-thioglucoside (n-heptyl-β-D-thioglucopyranoside), n-octyl-β-D-glucoside (n-octyl-β-D-glucopyranoside), wherein the surfactant is immobilized onto the porous membrane and present in a dry state, a porous solid phase for binding assay, a device comprising the binding assay strip, and binding assay method.
Patent EP-3012025-A2 (EP)
Title: Method of densifying a fibrous composition
Inventor: MEDOFF MARSHALL
IPC: C12P7/10
Filed: 2007-06-12
Abstract: Fibrous materials, compositions that include fibrous materials, and uses of the fibrous materials and compositions are disclosed. For example, the fibrous materials can be operated on by a microorganism to produce ethanol or a by-product, such as a protein or lignin. In particular, a method of densifying a fibrous composition is disclosed, the method comprising: shearing a fiber source to provide a fibrous material; combining the fibrous material with a microorganism and/or enzyme to provide a fibrous material composition; encapsulating the composition in a substantially gas impermeable material; and removing entrapped gas from the encapsulated composition to densify the composition.
Patent EP-3017951-A2 (EP)
Inventor: GHOZEIL ADAM L
IPC: B41J2/045
Filed: 2008-02-06
Abstract: A printhead (40) comprises a firing resistor (52), a switch (72) connected to a node (76) and configured to control current through the firing resistor (52), pre-charge transistor (74) configured to pre-charge the node (76) during a pre-charge cycle responsive to a pre-charge signal (PRE) providing a voltage pulse across the pre-charge transistor (74) to the node (76) to a pre-charge voltage level that is sufficient to turn on switch (72), and a first transistor having a first terminal connected to the node (76) and a second terminal connected to a reference potential and configured to selectively discharge the node (76) to the reference potential during a discharge cycle when a select signal (SEL) has a level to turn on the first transistor.
Patent EP-3116544-A2 (EP)
Inventor: WEISKOPF KIPP ANDREW
IPC: C07K16/00
Filed: 2015-03-11
Abstract: Anti-SIRPα antibodies, including multi-specific anti-SIRPα antibodies, are provided, as are related compositions and methods. The antibodies of the disclosure bind to SIRPα and can block the interaction of CD47 on one cell with SIRPα on a phagocytic cell. Antibodies that are bispecific for SIRPα and a second antigen are termed Bi-specific Macrophage Enhancing (BiME) antibodies and have emergent properties. The subject anti SIRPα antibodies find use in various therapeutic methods. Embodiments of the disclosure include isolated antibodies and derivatives and fragments thereof, pharmaceutical formulations comprising one or more of the anti-SIRPα antibodies; and cell lines that produce the antibodies. Also provided are amino acid sequences of exemplary anti-SIRPα antibodies.
Patent EP-3142698-A2 (EP)
Inventor: GURNEY AUSTIN L
IPC: C12N5/07
Filed: 2015-05-13
Abstract: L'invention concerne des agents de liaison qui modulent la réponse immunitaire. Ces agents de liaison peuvent comprendre des anticorps, des récepteurs solubles, et/ou des polypeptides L'invention concerne également des procédés d'utilisation de ces agents de liaison pour le traitement de maladies telles que le cancer.
Patent EP-3069831-A2 (EP)
Inventor: TANAKA KENTARO
IPC: B25J9/04
Filed: 2016-02-26
Abstract: A robot (10) includes a robot arm (12, 13, 14, 15), a balancer (17), and a first mounting portion (16b) and a second mounting portion (16a). The balancer (17) is pressurized in advance by a predetermined amount of pressure and contracted to a dimension smaller than a predetermined mounting dimension of the robot arm (12, 13, 14, 15). The first mounting portion (16b) and the second mounting portion (16a) are disposed on the robot arm to respectively accept a first end and a second end of the balancer (17) so that the first end and the second end of the balancer (17) are mounted on the robot arm (12, 13, 14, 15). At least one mounting portion among the first mounting portion and the second mounting portion accepts the corresponding end, among the first end and the second end, of the balancer (17) in a direction approximately parallel to a direction in which the balancer (17) is expanded and contracted.
Patent EP-3109727-A2 (EP)
Title: A method and apparatus for controlling a display, and a mobile terminal
Inventor: LIU ANYU
IPC: G06F3/0488
Filed: 2016-03-31
Abstract: A mobile terminal includes: a frame body (120) including a middle frame (122); a touch screen (140) provided on a front surface of the frame body and attached onto the middle frame; wherein the touch screen covers the whole of the front surface of the frame body, or the touch screen covers a remaining area except a predetermined area on the front surface of the frame body, the predetermined area being an exposure area for additional electronic devices provided on the front surface of the frame body; a touch integrated circuit connected with the touch screen; and a processor connected with the touch integrated circuit. According to the disclosure, the whole front surface of the frame body is covered by the touch screen without providing an upper area and a lower button area thereon.
Patent EP-3141249-A2 (EP)
Inventor: LU MING-CHANG
IPC: A61K33/36
Filed: 2016-08-15
Abstract: A method for treating a glycoprotein-related disease is disclosed, which comprises: administering a first effective amount of phenol red and a second effective amount of an organic arsenic compound to a subject in need thereof.
Patent EP-3310557-A2 (EP)
Inventor: HAGEDORN YVES
IPC: B33Y40/00
Filed: 2016-06-16
Abstract: L'invention concerne un mécanisme de transport de poudre de bas en haut pour une installation PBLS (1), qui comprend un réservoir (5b, 5c) fonctionnant sous la forme d'un réservoir de poudre avec un fond mobile à la manière d'un piston pour transporter la poudre en direction d'une ouverture supérieure du réservoir (5b, 5c) opposée au fond et/ou à travers l'ouverture supérieure du réservoir (5b, 5c) et la transporter ainsi vers un plan de travail de l'installation (1), le mécanisme de transport de poudre de bas en haut comprenant un réservoir externe (9) qui peut être fermé de manière étanche aux gaz et est relié à une conduite étanche aux gaz pour pouvoir diriger la poudre par l'intermédiaire de la conduite depuis le réservoir (9) jusque dans le réservoir (5b, 5c) fonctionnant sous la forme d'un réservoir de poudre. Afin de préparer un mécanisme de transport de poudre de bas en haut amélioré et en particulier qui puisse être agrandi de manière modulaire, l'invention prévoit que le réservoir (5b, 5c) fonctionnant sous la forme d'un réservoir de poudre comporte dans une paroi latérale (6b, 6c) en vis-à-vis de l'ouverture supérieure une ouverture inférieure (15a, 15b) qui permet de remplir de poudre le réservoir (5b, 5c) et qui peut être reliée à la conduite de manière étanche aux gaz et amovible pour pouvoir diriger la poudre entraînée par la force de la pesanteur depuis le réservoir externe (9) disposé au-dessus de l'ouverture (15a, 15b) à travers la conduite qui présente une descente et à travers l'ouverture inférieure (15a, 15b) dans le réservoir (5b, 5c) fonctionnant sous la forme d'un réservoir de poudre. L'invention concerne en outre une installation PBLS (1) qui comporte un mécanisme de transport de poudre de bas en haut et un procédé de modification d'une telle installation PBLS (1).
Patent EP-3313402-A2 (EP)
Title: Inhibiteurs de vmat2 pour le traitement de maladies ou troubles neurologiques
Inventor: O'BRIEN CHRISTOPHER F
IPC: A61P25/18
Filed: 2016-06-23
Abstract: L'invention concerne des méthodes pour le traitement d'une manie dans les troubles de l'humeur et d'autres maladies ou troubles neurologiques. Les méthodes de la présente invention comprennent l'administration d'un inhibiteur de VMAT2 à un sujet le nécessitant. Un inhibiteur de VMAT2 utilisé dans les méthodes susmentionnées comprend un acide (S)-2-Amino-3-méthyl-butyrique (2R,3R,11bR)-3-isobutyl-9,10-diméthoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline-2-yl ester.
Patent EP-3280799-A2 (EP)
Inventor: KYOSTIO-MOORE SIRKKA
IPC: C12N7/00
Filed: 2016-04-07
Abstract: Provided herein are methods for producing an adeno-associated virus (AAV) particle containing an oversized recombinant AAV genome (e.g., greater than 4.7 kb). In some aspects, the invention provides AAV particles and AAV vectors comprising oversized rAAV genomes. Producer cell lines to produce AAV particles comprising oversized genomes are also provided.
Patent EP-3321534-A2 (EP)
Inventor: CAPEK OLIVER
IPC: F16D41/07
Filed: 2017-11-07
Abstract: The present invention relates to an outer race (1) for a one-way clutch (100) comprising a race chamber (12) surrounded by circumferential wall (11) and comprising a plurality of roller chambers (13), the circumferential wall (11) inside the roller chambers (11) having a radial diameter gradually decreasing in a first circumferential direction (D1), comprising an end body (14) at a first end to be integral with the circumferential wall (11) and an opening (15) at a second end between the axial ends of the race chamber (12), comprising a groove (143) concave into the first end at the end body (14) within each of the roller chambers (13), and comprising a first transition (141) between the circumferential wall (11) inside the groove (143) and the end body (14) and a second transition (142) between the circumferential wall (11) outside the groove (143) and the end body (14), the radius of curvature of the first transition (141) being greater than the radius of curvature of the second transition (142).
Patent EP-3401684-A2 (EP)
Inventor: WALENSKY LOREN D
IPC: A61K38/17
Filed: 2009-10-09
Abstract: The invention provides a method for identifying a compound which modulates the activity of a BCL-2 family polypeptide, the method comprising: a) contacting said BCL-2 family polypeptide with a compound under conditions suitable for modulation of the activity of said BCL-2 family polypeptide; and b) detecting modulation of the activity of said BCL-2 family polypeptide by the compound, wherein the compound interacts with a binding site comprising one or more of an ±1 helix, ±2 helix, a loop between ±1-±2, ±6 helix, and select residues of ±4, ±5, and ±8 helices in said BCL-2 family polypeptide; wherein the interaction of the compound with the binding site occurs at a horizontal hydrophobic groove with or without a perimeter of charged and hydrophilic residues, a superior juxta-loop, an inferior juxta-loop, or combination thereof.
Patent EP-3482184-A2 (EP)
Inventor: HAFELLNER REINHARD
IPC: G01M17/007
Filed: 2017-07-05
Abstract: Die vorliegende Erfindung betrifft eine Plattform (100) zum Testen von Kollisionen oder kollisionsnahen Situationen zwischen einem Kollisionskörper, insbesondere einem Fahrzeug, und einem Testobjekt. Die Plattform (100) weist einen Grundkörper (101), welcher eine Bodenfläche (102) und eine gegenüber der Bodenfläche (102) ausgebildete Befestigungsfläche (103) aufweist, auf, wobei auf der Befestigungsfläche (103) eine Befestigungsvorrichtung (109) ausgebildet ist zum Befestigen des Testobjekts. Ferner weist die Plattform (100) zumindest ein Rollenelement (104) auf, welches an der Bodenfläche (102) angeordnet ist,wobei das Rollenelement (104) derart ausgebildet ist, dass der Grundkörper (101) mittels des Rollenelements entlang eines Bodens (105) verfahrbar ist. Eine Installationsbox (106) aufweisend ein Installationsvolumen ist in einer Aufnahmeöffnung des Grundkörpers (101) angeordnet, wobei die Installationsbox (106) derart in der Aufnahmeöffnung des Grundkörpers (101) vorgesehen ist, dass ein Temperierbereich der Installationsbox (106) in Kontakt mit einer Umgebung des Grundkörpers (101) ist. Der Temperierbereich ist aus einem Material ausgebildet, welches einen größeren Wärmeleitkoeffizienten aufweist als ein Material des Grundkörpers (101).
Patent EP-3452095-A2 (EP)
Title: Formulation de simmondsine
Inventor: Van Den Driessche Herman
IPC: A61K47/14
Filed: 2017-04-27
Abstract: L'invention concerne une formulation orale au moins partiellement entérique comprenant un ou plusieurs composants de jojoba, pour réguler, stimuler ou moduler des fonctions pour des patients souffrant d'une maladie dégénérative, ou pour des patients présentant un risque de souffrir d'une maladie dégénérative, ou pour des patients soumis à un traitement thérapeutique d'une maladie dégénérative.
Patent EP-3357649-A2 (EP)
Inventor: HASEGAWA HIROSHI
IPC: B25J9/16
Filed: 2018-02-05
Abstract: A control device includes a calculation unit that calculates a force control parameter related to force control of a robot by using machine learning, and a control unit that controls the robot on the basis of the calculated force control parameter.
Patent EP-3437571-A2 (EP)
Inventor: SURTI VIHAR C
IPC: A61B17/12
Filed: 2010-12-17
Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system includes a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left  in vivo  engaged with the tissue.
Patent EP-3601521-A2 (EP)
Inventor: JONES MARK E
IPC: C12M1/00
Filed: 2018-04-02
Abstract: Embodiments described herein generally provide for expanding cells in a cell expansion system. The cells may be grown in a bioreactor, and the cells may be activated by an activator (e.g., a soluble activator complex). Nutrient and gas exchange capabilities of a closed, automated cell expansion system may allow cells to be seeded at reduced cell seeding densities, for example. Parameters of the cell growth environment may be manipulated to load the cells into a particular position in the bioreactor for the efficient exchange of nutrients and gases. System parameters may be adjusted to shear any cell colonies that may form during the expansion phase. Metabolic concentrations may be controlled to improve cell growth and viability. Cell residence in the bioreactor may be controlled. In embodiments, the cells may include T cells. In further embodiments, the cells may include T cell subpopulations, including regulatory T cells (Tregs), for example.
Patent EP-3612564-A2 (EP)
Inventor: MARGOLIN DAVID H
IPC: A61K39/00
Filed: 2018-04-20
Abstract: La présente invention concerne le traitement de formes récurrentes et progressives de la sclérose en plaques à l'aide d'un anticorps monoclonal humain anti-CD52 IgG1 humanisé.
Patent EP-3678204-A2 (EP)
Inventor: KIM HAE SIK
IPC: H01L51/00
Filed: 2018-08-24
Abstract: A mask for deposition of a metallic material for depositing OLED pixels according to an embodiment, wherein the mask for deposition comprises a deposition region for forming a deposition pattern and a non-deposition region other than the deposition region, the deposition region comprises a plurality of effective portions spaced apart in a longitudinal direction and non-effective portions other than the effective portions, an effective portion comprises a plurality of small surface holes which are formed on one surface; a plurality of large surface holes which are formed on the other surface opposite to the one surface; through-holes which communicate with the small surface holes and the large surface holes; and island portions between the plurality of through-holes, the diameter of the through-hole is 33µm or less, a resolution of 500 PPI or more, in which the spacing between the through-holes is 48µm or less, is provided, an inclination angle of the small surface holes with respect to the one surface is 70° to 89°, and the inclination curvature radius of the small surface holes with respect to the one surface is 3µm to 86µm.
Patent EP-3540502-A2 (EP)
Inventor: LEE JEIN
IPC: H05K5/02
Filed: 2014-11-26
Abstract: Provided is a display device which may include a display panel (420) having a long side (LS1, LS2) in a first direction (DR1), a short side (SS1, SS2) in a second direction (DR2), and a thickness in a third direction (DR3), a back cabinet (460) disposed in the rear of the display panel (420), and a case (410) that covers an edge of a front surface of the display panel (420). The case (410) may include a horizontal case (410H1, 410H2) that covers an edge of the front surface of the display panel (420) on a long side (LS1, LS2) of the display panel (420) and a vertical case (410V1, 410V2) covering an edge of the front surface of the display panel (420) on a short side (SS1, SS2) of the display panel (420). The horizontal case (410H1, 410H2) and the vertical case (410V1, 410V2) may be coupled to each other in a region corresponding to a corner of the display panel (420), and the horizontal case (410H1, 410H2) and the vertical case (410V1, 410V2) may be formed of different materials.
Patent EP-3737503-A2 (EP)
Inventor: ROTHBERG JONATHAN M
IPC: B01L3/00
Filed: 2019-01-04
Abstract: Apparatus and techniques for electrokinetic loading of samples of interest into sub- micron-scale reaction chambers are described. Embodiments include an integrated device and related apparatus for analyzing samples in parallel. The integrated device may include at least one reaction chamber formed through a surface of the integrated device and configured to receive a sample of interest, such as a molecule of nucleic acid. The integrated device may further include electrodes patterned adjacent to the reaction chamber that produce one or more electric fields that assist loading the sample into the reaction chamber. The apparatus may further include a sample reservoir having a fluid seal with the surface of the integrated device and configured to hold a suspension containing the samples.
Patent EP-3762508-A2 (EP)
Inventor: HOGAN MICHAEL EDWARD
IPC: G16B25/30
Filed: 2019-03-08
Abstract: Provided herein is a three-dimensional lattice microarray system for DNA sequence detection and analysis and kits including components of the same. In the system a solid support has a plurality of bifunctional polymer linkers, optionally with a fluorescent label, each with a top domain and a bottom end attached thereto at the bottom end and a plurality of nucleic acid probes attached to the top domain of the plurality of bifunctional polymer linkers. Also provided is a method for fabricating the microarray system and methods to detect and identify pathogens in a plant sample or to determine copy number of a pathogen DNA in an unpurified nucleic acid sample by using a known copy number of synthetic DNA as an internal standard.
Patent EP-3887570-A2 (EP)
Inventor: HIESTER JAVOB LEE
IPC: C23C16/458
Filed: 2019-11-14
Abstract: A pedestal assembly including a pedestal for supporting a substrate. A central shaft positions the pedestal at a height during operation. A ring is placed along a periphery of the pedestal. A ring adjuster subassembly includes an adjuster flange disposed around a middle section of the central shaft. The subassembly includes a sleeve connected to the adjuster flange and extending from the adjuster flange to an adjuster plate disposed under the pedestal. The subassembly includes ring adjuster pins connected to the adjuster plate and extending vertically from the adjuster plate. Each of the ring adjuster pins being positioned on the adjuster plate at locations adjacent to and outside of a pedestal diameter. The ring adjuster pins contacting an edge undersurface of the ring. The adjuster flange coupled to at least three adjuster actuators for defining an elevation and tilt of the ring relative to a top surface of the pedestal.
Patent EP-3894550-A2 (EP)
Inventor: HOU ZHENGLIN
IPC: C12Q1/68
Filed: 2019-12-13
Abstract: Compositions and methods are provided for genome modification of a target sequence in the genome of a cell, using a novel Cas endonuclease. The methods and compositions employ a guide polynucleotide/endonuclease system to provide an effective system for modifying or altering target sequences within the genome of a cell or organism. Also provided are novel effectors and endonuclease systems and elements comprising such systems, such as guide polynucleotide/endonuclease systems comprising an endonuclease. Compositions and methods are also provided for guide polynucleotide/endonuclease systems comprising at least one endonuclease, optionally covalently or non-covalently linked to, or assembled with, at least one additional protein subunit, and for compositions and methods for direct delivery of endonucleases as ribonucleotide proteins.
Patent EP-3760291-A2 (EP)
Inventor: POTT ROBERT WILLIAM MCCLELLAND
IPC: B01D11/02
Filed: 2020-07-01
Abstract: The invention provides a method for separating a polyphenolic compound such as resveratrol from biomass. The method comprises feeding the biomass into an aqueous two-phase system with a polymer phase and a salt phase and separating the polymer phase which includes the polyphenolic compound from the salt phase. The polymer may be a polyether. The salt may be a tartrate salt, a citrate salt, a carbonate salt, a phosphate salt or a sulphate salt. The biomass may be derived from grape vines, knotweeds, pine trees, peanut plants, cocoa bushes,  Vaccinium  shrubs; geraniums of the  Pelargonium  genus, or the herb  Polygonum Cuspidatum , for example. The biomass may be derived from winery waste. The polymer phase may comprise 10% (w/w) polyethylene glycol with a molecular weight of 8000 g/mol. The salt phase may comprise 15% (w/w) tartrate salt. The invention extends to medicaments and dietary supplements which include the polyphenolic compound.