baber/WOPTO huggingface dataset:
Patent BG-66301-B1 (BG)
Title: Broadspectrum 2-(substituted-amino)-benzothiazole sulfonamide hiv protease inhibitors
Inventor: SURLERAUX DOMINIQUE
IPC: A61K31/4439
Filed: 2003-09-01
Abstract: The present invention concerns the compounds having the formula N-oxides, salts, stereoisomeric forms, racemic mixtures, prodrugs, esters and metabolites thereof, wherein R1 and R8 each are H, optionally substituted C1-6 alkyl, C2-6 alkenyl, C3-7 cycloalkyl, aryl, Het1, Het2 R1 may also be a radical of formula (R11aR11b)NC(R10aR10b)CR9-;@T is 0, 1 or 2 R2 is H or C1-6 alkyl L is -C(=O)-, -O-C(=O)-, -NR8-C(=O)-, O-C1-6 alkanediyl-C(=O)-, -NR8-C1-6 alkanediyl-C(=O)-, -S(=O)2-, -O-S(=0)2-NR8-S(=O)2 R3 is C1-6 alkyl, aryl, C3-7 cycloalkyl, C3-7 cycloalkyl C1-4 alkyl, or arylC 1-4 alkyl R4 isH, C1-4 alkyl OC(=O), carboxyl, amino C(=O), mono or di(C1-4 alkyl) amino C(=O), C3-7 cycloalkyl, C2-6 alkenyl, C2-6 alkynyl or optionally substituted C1-6 alkyl A is C1-6 alkanediyl, -C(=O)-, -C(=S)-, (S=0)2-C1-6 alkanediyl-C(=O)-, C1-6 alkanediyl-C(=S)- or C1-6 alkanediyl-S(=O)2- R5 is H, OH, C1-6 alkyl, Het1C1-6alkyl, Het2C1-6alkyl, optionally substituted amino C1-6 alkyl R6 is C1-6 alkylO, Het1, Het1O, Het2, Het2O, aryl, arylO, C1-6 alkyloxycarbonylamino or amino and in case -A- is other than C1-6 alkanediyl then R6 may also be C1-6 alkyl, Het1C1-4 alkyl, Het1OC 1-4 alkyl, Het2 C1-4alkyl, Het2OC 1-4 alkyl, arylC 1-4 alkyl, arylOC 1-4 alkyl or aminoC 1-4 alkyl whereby each of the amino groups in the definition of R6 may be optionally be substituted R5 and -A-R6 taken together with the nitrogen atom to which they attached may also form Het1 or Het2. It further relates to their use as broadspectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. It also concerns combinations thereof with another anti-retroviral agent, and to their use in assays as reference compounds or as reagents. 51 claims@
Patent BG-66144-B1 (BG)
Title: A cylindrical straight gear transmission with external meshing
Inventor: ALIPIEV OGNYAN
IPC: F16H1/04
Filed: 2009-01-06
Abstract: The cylindrical straight gear transmission with external meshing finds application in transmission boxes, reducers, gear hydro machines, compressors, and others. By it may be transferred continuous rotational motion from one gear to another in case of small number of teeth. The transmission contains a driving (1) and a driven (2) gear with parallel axes of rotation and small number of straight teeth with nonsymmetrical profiles. The teeth have a concave (4) and a convex (3) side and are profiled by three different curves. The first one (MN), outlining the concave side (4), is an equidistant curve of an elongated epicycloid. By the second (KL), which is an evolvent curve, is profiled the convex side (3), while by the third (LM) is shaped the top of the tooth (5) as a circular arc. The concave tooth profile (4) of one of the gears is a wrapper of the relative positions, which occupy the top round profile (5) of the other gear during their turn, and the evolvent profiles (3) of the driving and driven gear are with increased length what provides for their uninterrupted meshing with a ratio of face overlapping larger than one.
Patent BG-66608-B1 (BG)
Title: Polybacterial probiotic preparation
Inventor: DIMITROV ZHECHKO
IPC: A23L7/109
Filed: 2011-05-04
Abstract: The present invention relates to a polybacterial probiotic preparation that comprises novel strains of lactic acid bacteria Lactobacillus gasseri 7/12, registered in NBIMCC under No 8720, Lactobacillus plantarum F12, registered in NBIMCC under No 8722, Lactobacillus helveticus A1, registered in NBIMCC under No 8721, and has the following set of properties: antioxidant effect, hypocholesterolemic effect, anti-inflammatory immunomodulating effect, ability to release bioactive peptides that inhibit angiotensin-converting enzyme (ACE), which is responsible for high blood pressure. Subject of the invention are also the indicated probiotic strains of lactic acid bacteria, bacterial compositions, prepared by them, and their useful properties. The included in the composition probiotic strain Lactobacillus gasseri 7/12, registered in NBIMCC under No 8720 has a number of properties: strong adhesion to the epithelial layer of the colon, ability for reduction of cholesterol and anti-inflammatory effect by reducing the level of the proinflammatory cytokine- interleukin- 8. The invention also relates to use of the strains of lactic acid bacteria and bacterial compositions in the manufacture of starter cultures, food additives, foods, functional products and pharmaceutical compositions, intended to affect the health condition of humans and animals.
Patent BG-67381-B1 (BG)
Title: Electronic device with planar magnetic sensitivity
Inventor: LOZANOVA SIA
IPC: H01L43/06
Filed: 2019-09-03
Abstract: The electronic device with planar magnetic sensitivity contains a current source (1) and a rectangular semiconductor wafer(2) with n-type hopping conduction. On its upper side are formed three rectangular ohmic contacts successively and at equal distances from each other, from left to right - first (4), second (6) and third (8), located parallel to their long sides, as the second contact (6) is central, and the first (4) and the third (8) are symmetrical with respect to it. The first (4) and the third contact (8) are connected to the current source (1), as the external measured magnetic field (11) is in the plane of the wafer (1) and is parallel to the long sides of the contacts (4, 6 and 7). There is also a second semiconductor wafer (3), located parallel to the first one (2) with its long sides and identical to it - with the same type of hopping conduction, number of contacts on one side and distances between them. The first contact (4) of the first wafer (2) is connected to the third contact (9) of the second (3) and the third contact (8) of the first wafer (2) is connected to the first contact (5) of the second wafer (3). The two central contacts (6 and 7) are the output (10) of the electronic device.
Patent CH-706915-B1 (CH)
Title: Revêtement anti-ternissement sur composants horlogers.
Inventor: AGNÈS MARLOT DOERR
IPC: G04D3/00
Filed: 2012-09-05
Abstract: L’invention concerne un composant (1) d’horlogerie comportant au moins une surface (2) en alliage d’or et/ou d’argent et/ou d’autre métal précieux. Il comporte au moins une couche superficielle (4) constituée de revêtement polymère à base de poly(para-xylènes) pour sa protection contre le ternissement et/ou la décoloration. L’invention concerne également un procédé de protection anti-ternissement pour composant (1) d’horlogerie comportant au moins une surface (2) en alliage d’or et/ou argent et/ou d’autre métal précieux, caractérisé en ce qu’on effectue sur ledit composant un revêtement polymère à base de poly(para-xylènes) par procédé CVD. Plus particulièrement, selon ce procédé, on effectue les opérations suivantes: nettoyer ladite au moins une surface (2); effectuer le dépôt de revêtement polymère à base de poly(para-xylènes), en une ou plusieurs couches (4) par procédé CVD.
Patent CH-718213-B1 (CH)
Title: Verbindungsvorrichtung zur Herstellung einer elektrischen Verbindung.
Inventor: BEAT KELLER
IPC: H01R4/24
Filed: 2020-12-23
Abstract: Die Erfindung betrifft eine Verbindungsvorrichtung (1) zur Herstellung einer elektrischen Verbindung mit wenigstens einem elektrischen Leiter (2) aufweisend einen Metalldraht (22) mit einem Isoliermantel (21). Die Vorrichtung umfasst ein Gehäuse (4) zur Aufnahme des mindestens einen elektrischen Leiters (2) mit mindestens einer Öffnung (3) zum Einschieben des mindestens einen elektrischen Leiters (2) in einer Einschubrichtung (ER). Ferner umfasst die Vorrichtung eine Stromleitschiene (5), eine Federkraftklemme (61) mit einer Mündung (62) und eine mit dieser Mündung (62) verbundenen Federzunge (63), wobei der elektrische Leiter (2), in der Mündung (62) zwischen der Federzunge (63) und der Stromleitschiene (5) selbsthemmend fixierbar ist. Erfindungsgemäss, weist das Gehäuse (4) in Einschubrichtung (ER) gesehen, eine der Stromleitschiene (5) vorgelagerte Schneide (7) verbunden mit einem federnden Lager auf, wobei die Schneide (7) dazu eingerichtet ist, den Isoliermantel (21) entlang der Längsachse des elektrischen Leiters (2) zu entfernen, bevor der elektrische Leiter (2) mit seinem Metalldraht in Kontakt mit der Stromleitschiene (5) tritt.
Patent EP-1072998-B1 (EP)
Inventor: BRAUN GERHARD
IPC: G06K7/00
Filed: 2000-06-05
Granted: 2004-08-04
Abstract: The contact unit has a base (12) and a hinged cover (14) . The cover is formed to allow insertion of a smart card (20) from one end, The base has contacts (22) that are engaged by the card when the cover is closed against the base. An additional contact activates the unit.
Patent EP-1076025-B1 (EP)
Inventor: BORTOLOTTI GIUSEPPE
IPC: B65H1/14
Filed: 2000-07-04
Granted: 2006-03-29
Abstract: Sheet feeding device comprises a movable support (17) where a stack of sheets may be arranged and resiliently urged against selection wheels (19). A retracting mechanism (50) is arranged so as to push back during one phase of a selection cycle the movable support (7) by a predetermined distance which is substantially constant and independent of the thickness of the stack of sheets. The retracting mechanism (50) for this purpose comprises a connecting rod (58) displaced by a cam wheel (66) following a backward and forward movement. - DETAILED DESCRIPTION - The connecting rod (58) bears a pawl (57) cooperating with a ratchet wheel (56) suitable for driving a lever (51) integral with the movable support (17). Additionally an actuating mechanism permits the partial opening of the guiding channel (28) when the sheet arrives in a printing zone (35).
Patent EP-1184969-B1 (EP)
Inventor: SCHALLNER MARTIN
IPC: H03B19/05
Filed: 2000-08-16
Granted: 2004-01-14
Abstract: A frequency-generator circuit employs the same circuit element (preferably a varactor) to perform the functions of parametric frequency-divider and frequency-adjustment element for an oscillator used to pump the parametric frequency-divider.The varactor preferably has a flat gamma-characteristic (gamma preferably > 2) over a required bias-voltage adjustment range corresponding to the required frequency-adjustment range. <IMAGE>
Patent EP-1028102-B1 (EP)
Inventor: DESIKAN ANANTHA NARAYAN
IPC: C07C37/48
Filed: 2000-01-27
Granted: 2005-05-25
Abstract: The isomerization of an alkylated phenol composition that contains an ortho-alkyl substituted phenol component to isomerize and reduce the level of ortho-alkyl substituted phenol component therein can be accomplished by heating that composition in the presence of a catalytically effective amount of a solid acid catalyst to carry out such isomerization and reduction in the level of ortho-alkyl substituted phenol. Examples of suitable solid acid catalysts include H-form zeolites, supported sulfonic acids, and supported heteropoly acids. The resulting isomerized product can be subsequently phosphorylated.
Patent EP-1041352-B1 (EP)
Inventor: LACROIX JEAN-JACQUES
IPC: F24H9/12
Filed: 2000-03-23
Granted: 2004-05-12
Abstract: Support (20) comprises quick-release coupling (11, 12), able to be integrated in water alimentation system (1, 2) for hot wa slots (25a, 25'a, 25b, 25'b), used as guiding system, for sliding in translation heater (30) in direction of connection (F) of f quick-release coupling with second one, attached to heater. An Independent claim is also included for the description of the quick-release coupling mechanism, and for the method for attaching the heater on its support.
Patent EP-1154970-B1 (EP)
Inventor: BERRETH KARL
IPC: C04B35/573
Filed: 2000-01-14
Granted: 2004-11-03
Abstract: The invention relates to a fiber-reinforced ceramic body and a method for producing same. The ceramic body consists of a core and a boundary layer (93, 94) which is joined to the core and has at least one outer surface (96, 97) which can preferably be subjected to tribological stress. The core consists of one or more layers (92) of which at least one is reinforced with long fibers. The boundary layer (93, 94) is reinforced with short fibers. The fibers are preferably reaction-bonded in a matrix by melt infiltration and are made of high-temperature resistant fibers with covalent bonds on the basis of silicon, carbon, boron or nitrogen.
Patent EP-1078426-B1 (EP)
Inventor: TRIEPELS JOZEPH W
IPC: G02F1/13
Filed: 2000-02-14
Granted: 2004-11-24
Abstract: Des tracés de conducteurs (8) situés sur une carte ou sur un substrat (9) sont connectés à des tracés de conducteurs (14) situés sur un substrat d'un dispositif d'affichage (3) par des contacts or-or. On obtient des contacts par pression très fiables, notamment si on utilise des interconnexions (15) résistantes.
Patent EP-1159776-B1 (EP)
Inventor: LEGAY PHILIPPE
IPC: H01S5/10
Filed: 2000-03-07
Granted: 2003-05-28
Abstract: An optoelectronic system comprising at least three sections corresponding to specific respective functions and having different respective band gap energies, at least for the adjacent pairs of sections. These three sections consist of at least two layers superposed by epitaxy. The upper layer is etched in order to define said sections in the form of two separate end sections defined in the upper layer on each side of an intermediate section defined in the lower layer, and to allow coupling between the intermediate section and each of the end sections which flank it, by evanescent coupling. The length of the intermediate section is such that the product KxL, in which K represents the coupling coefficient of a grating of the intermediate section, is one of the order of 1.</PTEXT>
Patent EP-1163349-B1 (EP)
Inventor: SELDEN RICHARD F
IPC: C12N15/54
Filed: 2000-03-09
Granted: 2008-02-20
Abstract: The invention provides highly purified ±-Gal A, and various methods for purifying it; ±-Gal A preparations with altered charge and methods for making those preparations; ±-Gal A preparations that have an extended circulating half-life in a mammalian host, and methods for making same; and methods and dosages for administering an ±-Gal A preparation to a subject.
Patent EP-1069832-B1 (EP)
Inventor: ANDELA CARL SIDONIUS MARIA
IPC: A23K1/165
Filed: 2000-02-10
Granted: 2004-05-06
Abstract: A process for the preparation of an enzyme-containing granulate is disclosed where an aqueous enzyme-containing liquid is mixed with a solid carrier and optionally additive ingredients and is mechanically processed into granules, dried and subsequently coated with polyethylene glycol. The solid carrier preferably essentially consists of an edible carbohydrate polymer. Additive ingredients that could be further incorporated in the formulation of the granules are a gel-forming or slow dissolving compound such as polyvinyl alcohol, water soluble inorganic salts comprising divalent cations and trehalose. This enzyme granulate is suitable for the manufacture of animal feed compositions by mixing feed ingredients with the granulate, treating with steam and pelleting. The compositions show improved enzyme stability during the pelleting process and during storage. At the same time, the dissolution time of the granule is very short so that the bioavailability of the enzyme to the animal is improved.
Patent EP-1166020-B1 (EP)
Inventor: BENSON ROBERT A
IPC: F16L55/26
Filed: 2000-03-21
Granted: 2007-01-03
Abstract: A source fluid from which solid material forms when it is cooled is passed through apparatus which defines a continuous reentrant lumen. The lumen has a thermally conductive processing wall from which heat is extracted from the outside as the source fluid flows through the lumen, resulting in formation of solid material on the inner surface of the lumen wall. A runner circulates around the lumen and dislodges material deposited on the inner surface of the lumen wall. This material is then carried as solids of a slurry out of the apparatus with the fluid stream.
Patent EP-1196155-B1 (EP)
Title: Nouvelle utilisation de composes comme agents antibacteriens
Inventor: EEK ARNE
IPC: A61K31/381
Filed: 2000-05-25
Granted: 2004-08-04
Abstract: La présente invention concerne une nouvelle utilisation d'AINS à libération de NO, particulièrement les AINS à libération de NO représentés par la formule (I), ou un sel de ceux-ci acceptable sur le plan pharmaceutique ou un énantiomère, destinée à la fabrication d'un médicament devant traiter les infections bactériennes, particulièrement celles provoquées ou véhiculées par Helicobacter pylori. En outre, cette invention concerne la nouvelle utilisation d'AINS à libération de NO en association avec un inhibiteur de pompe à protons sensible à l'acide pour traiter les infections bactériennes.
Patent EP-1097042-B1 (EP)
Inventor: WEBER KLAUS
IPC: B65C9/30
Filed: 2000-04-22
Granted: 2003-07-09
Abstract: Described is a process for the region-wise transfer of a decorative layer of a transfer foil, which includes an activatable adhesive layer from a carrier film onto a substrate, wherein the adhesive layer of the transfer foil is partially activated before the actual stamping operation, more specifically in such a way that the adhesive layer experiences activation only in the surface regions in which the decorative layer is to be transferred onto the substrate. A transfer foil which is particularly suitable for that process has an absorption layer in the surface regions of the decorative layer, which are to be transferred onto the substrate, which absorption layer absorbs the radiation energy causing activation of the adhesive layer and activates the adhesive layer under the action of the absorbed radiation energy.
Patent EP-1228280-B1 (EP)
Inventor: WEBER HUGO
IPC: E04D1/34
Filed: 2000-06-04
Granted: 2004-10-13
Abstract: At least one end (1a) of the covering (1) is provided with a raised profile (4). Plants are prevented from growing on the roof, and environmental pollution is prevented from making the roof dirty by using a roof covering made from a metal which reacts in the presence of water. The covering is made from sheet metal by punching and bending in order to form a structured outer surface (2).
Patent EP-1203397-B1 (EP)
Inventor: MILLER RAANAN A
IPC: G01N27/64
Filed: 2000-06-29
Granted: 2011-08-10
Abstract: A micromechanical field asymmetric ion mobility filter for a detection system includes a pair of spaced substrates defining between them a flow path between a sample inlet and an outlet; an ion filter disposed in the path and including a pair of spaced filter electrodes, one electrode associated with each substrate; and an electrical controller for applying a bias voltage and an asymmetric periodic voltage across the ion filter electrodes for controlling the paths of ions through the filter.
Patent EP-1214838-B1 (EP)
Inventor: JOHANSSON HANS
IPC: H04M3/00
Filed: 2000-08-04
Granted: 2005-02-23
Abstract: To shorten the recovery time of a line driver (1) after an overvoltage on its output terminal (3), a current generating device (5) senses a voltage difference between the output voltage of the line driver (1) and its supply voltage (UB) plus a threshold voltage (UT'), and supplies a current (I) that is proportional to the sensed voltage difference up to a maximum current to the output (3) of the line driver (1) to raise its potential to thereby shorten its recovery time.
Patent EP-1240553-B1 (EP)
Inventor: PADMANABAN MUNIRATHNA
IPC: H01L21/027
Filed: 2000-11-18
Granted: 2009-06-17
Abstract: The present invention relates to a novel photoresist composition sensitive in the deep ultraviolet region, where the photoresist performance is not adversely impacted by basic contaminants in the processing environment of the photoresist. The novel photoresist comprises a polymer, a photoactive compound, a basic compound that is a sulfonium or iodonium compound that is essentially nonabsorbing at the exposure wavelength of the photoresist, and a solvent composition. The invention further relates to a process for imaging such a photoresist in the deep ultraviolet region.
Patent EP-1248533-B1 (EP)
Inventor: CHIDLEY FRANCIS JOHN
IPC: A23L1/304
Filed: 2000-12-21
Granted: 2005-03-16
Abstract: The invention provides a method of packaging an aqueous liquid whereby a charge of the liquid is charged through a closable opening into acontainer. A source of inorganic ions which are soluble in the liquid is also inserted into the container. The opening is then closed to retain the liquid and the source in the container. There is also provided a liquid pack comprising a container having a closable opening and an aqueous liquid in the container. A source of inorganic ions in the container contacts the liquid, the ions being soluble in the liquid and the source comprising a carrier for said ions of solid material insoluble in the liquid and having said ions sorbed thereto. The invention also provides a device comprising said source and a receptacle in which it is held captive.
Patent EP-1230094-B1 (EP)
Inventor: SCHUMACHER MATTHIAS
IPC: B41M5/26
Filed: 2000-10-18
Granted: 2004-01-14
Abstract: The invention relates to a method for applying coloured characters on a data storage medium, which is preferably made from plastic, by means of a laser system, whereby latent pigments are applied in at least one surface layer and/or surface adjacent layer. The absorption characteristics of said latent pigments can be changed by energetic stimulation. Said stimulation occurs in those areas of the surface of the data storage medium allotted to the characters, by means of laser radiation in the IR/visible region, whose energetic stimulation is such that a colour change occurs in said latent pigments. After said colour change in the laser irradiated latent pigments, the latent pigments which have not been stimulated by laser irradiation are irradiated by light in the UV wavelength region, whose energetic stimulation is such that the pigments, irradiated by this means, are rendered colourless.
Patent EP-1222289-B1 (EP)
Inventor: WU TZYY-CHOOU
IPC: C07K14/35
Filed: 2000-10-20
Granted: 2008-04-16
Abstract: The invention provides chimeric nucleic acids encoding a chimeric polypeptide, constructs for expressing these polypeptides both in vitro and in vivo, isolated chimeric polypeptides, pharmaceutical compositions and methods of making and using these compositions. These compositions and methods are particularly useful for stimulating or enhancing the immunogenicity of a selected antigen or stimulating or enhancing a cellular immune response specific for that antigen. The nucleic acid of the invention comprises a first polypeptide domain comprising a carboxy terminal fragment of a heat shock protein (HSP), an Flt-3 ligand (FL), a cytoplasmic translocation domain of a Pseudomonas exotoxin A (ETA dII), or a granulocyte-macrophage-colony stimulating factor (GM-CSF) sequence, and a second polypeptide domain comprising an antigenic polypeptide.
Patent EP-1250691-B1 (EP)
Inventor: DUKASH SEMYON
IPC: G06Q30/00
Filed: 2000-12-15
Granted: 2006-05-17
Abstract: A system shows messages on electronic displays, including networks of outdoor displays, such as displays mounted on vehicles. With such vehicle displays, a display's current geographical location can be sensed, such as by a GPS receiver in the vehicle or by multiple wireless receivers separate from the vehicle. The sensed location can then be used to select which messages are shown the display. Different values can be associated with showing messages on displays at different locations and times, and values associated with the locations and time through which a display travels can be summed, such as for charging advertisers or crediting vehicle operators. The system can be controlled by a computer system, such as an e-commerce site, which allows advertisers to upload message content, select messages, and select the time and place at which a messages is to be shown, either directly or by specifying criteria for the system to select such times and places. Message content and information controlling which messages are shown when and where can be downloaded to display, such as by wireless.