baber/WOPTO huggingface dataset:
Patent EP-2280728-A2 (EP)
Title: Vaccin combine rougeole-papillome humain
Inventor: MENDIRETTA SANJEEV K
IPC: A61K39/12
Filed: 2009-05-26
Abstract: L'invention concerne des vaccins combinés contre la rougeole et le papillomavirus humain (HPV). Plus précisément, l'invention concerne des vecteurs du virus de la rougeole recombiné contenant de l'acide nucléique hétérologue codant un ou plusieurs antigènes dérivés du HPV, de préférence, l'antigène de capside majeur L1, l'antigène de capside mineur L2, les oncoprotéines des gènes précoces E6 et E7 du type HPV 16, et éventuellement des types 18, 6 et 11. Dans un premier mode de réalisation, les vaccins prophylactiques sont générés pour exprimer des antigènes de HPV, de préférence L1 et/ou L2 de façon qu'ils induisent une réponse immune puissante et de longue durée chez les mammifères, de préférence chez les humains, pour les protéger contre l'infection par le HPV et le MV. Dans un autre mode de réalisation, des vaccins thérapeutiques sont générés pour exprimer des protéines E6 et E7, et éventuellement L1 et L2, de façon à induire des réponses immunes puissantes, et permettront de guérir des infections par HPV à des stades précoces ou tardifs, y compris le carcinome du col de l'utérus induit par HPV. Dans un mode de réalisation préféré, les vaccins combinés sont aisés à produire sur une grande échelle et peuvent être distribués à bas prix.
Patent EP-2264048-A2 (EP)
Inventor: SOUZA DOS SANTOS ROBSON AUGUSTO
IPC: C07K7/14
Filed: 2009-02-13
Abstract: "PEPTIDE DES-[ASP 1 ]-[ALA 1 ] ANGIOTENSIN-(1-7) AGONIST AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DISEASES" 
     
     The present invention is related to the peptide Des-[Asp 1 ]-[Ala 1 ]-Angiotensin-(1-7) (Ala 1 -Arg 2 -Val 3 -Tyr 4 -Ile 5 -His 6 -Pro 7 ) and/or its related compounds as vasodilating and cardioprotective agents to be used in mammals. This invention also comprises the production of compositions containing Des-[Asp 1 ]-[Ala 1 ]-Angiotensin-(1-7) and/or its related compounds and its use in methods for treating and preventing diseases.
Patent EP-2218929-A2 (EP)
Inventor: REINICKE ROLF
IPC: F16C33/20
Filed: 2010-02-11
Abstract: The material has a metallic supporting layer (4) made up of steel, and plastic sliding layer made up of polymer material. Recesses (8) is flanked by an enamel bell mouth (12) whose height is above a unstructured surface level of 10-100 micro meter and breadth is about 10-80 micro meter. The recesses and enamel bell mouth apply an undercut (16) to a normal surface (14) for directly and indirectly producing the recesses on the metallic supporting layer in a liquid, molten and solid state. The recesses are formed in a supporting layer impressed by the polymer material. The polymeric material is selected from a mixture consists of polyphenylene sulfide, protactinium, polyetheretherketone, or polyphosphoric acid, mica and iron oxide, and polyethersulfone.
Patent EP-2226920-A2 (EP)
Inventor: APPEL CHRISTIAN
IPC: F24D18/00
Filed: 2010-03-08
Abstract: The block heating assembly comprises a combustion piston engine (42) and an electric generator (44), which are coupled together by a power transmitting shaft (46). The generator has a stator (72) and a rotor (60), where the rotor is supported. A combustion piston engine housing (52) forms the stator housing (70) which is flanged in the combustion piston engine housing.
Patent EP-2253389-A2 (EP)
Inventor: AKAGI TAKUMA
IPC: B07C3/00
Filed: 2010-03-12
Abstract: In a sorting apparatus (1), an image on the paper sheet is read by a scanner (14), and from the read image on the paper sheet, characters of the destination information are recognized by a character recognition unit (22). If the address information included in the destination information as a character recognition result obtained by the character recognition unit (22) matches with the address information having an out-migrant included in relocation information previously registered in a database (6), it is judged by a judgment unit (21) whether the receiver on the paper sheet is the out-migrant. If it has been judged that the receiver on the paper sheet is the out-migrant, a label on which the address information of a new address of the out-migrant is written is attached to an attaching position considering a description area of the destination information on the paper sheet by a label attachment unit (16).
Patent EP-2260770-A2 (EP)
Inventor: BRETT GERARD
IPC: A61B17/3209
Filed: 2006-04-28
Abstract: An interventional medical closure device (300) is suitable for assisting closure of an opening through a blood vessel wall after completion of an interventional procedure within the internal lumen of the blood vessel. The device (300) comprises a closure element, a grasping element (302) for grasping the closure element, and a delivery element (304) for delivering the closure element into the internal lumen of the blood vessel. The closure element comprises a suture, and an engagement foot at a distal end of the suture. The grasping element (302) is inter-engageable with the closure element to grasp the closure element. The delivery element (304) comprises a main body portion, and a distant nose (314). The distal nose (314) defines a reception space for carrying the engagment foot of the closure element. The delivery element (304) also comprises an engagement foot (316) which is movable relative to the main body portion between a low-profile delivery configuration and a protruding engagement configuration.
Patent EP-2239177-A2 (EP)
Inventor: KEMMANN OLIVER
IPC: B61D27/00
Filed: 2010-02-16
Abstract: The method involves signalizing smoke detection in a fire-loaded coach or coach group with an air conditioning system. The system is controlled in such a manner that delivery air is reduced and/or exhaust air is enlarged in the fire-loaded coach or coach group. The fire-loaded coach or coach group is combined with a virtual coach section. Pressure lying below atmospheric pressure is adjusted in the coach and/or the coach group affected by fire. Fire protection devices e.g. smoke aprons or foldable cover elements are installed for optimizing supply of delivery and exhaust air. An independent claim is also included for a rail vehicle comprising an air conditioning system.
Patent EP-2221260-A2 (EP)
Inventor: HOELLRIEGL THOMAS
IPC: B25J15/00
Filed: 2010-02-17
Abstract: The element (1) has a carrier (2) on which a gripping head (4) is arranged. The gripping head is partially introduced into a mouth of a plastic container. Holding elements (6a) are arranged on the gripping head and movable in radial direction (R) in relation to the gripping head to secure the container relative to the gripping head. A section of one holding element is pressed against an inner wall of the mouth. The holding elements are uniformly distributed on the gripping head around a circumference of the gripping head.
Patent EP-2239342-A2 (EP)
Inventor: MCKERNAN KEVIN
IPC: C12Q1/68
Filed: 2006-02-01
Abstract: The present invention provides methods for determining a nucleic acid sequence by performing successive cycles of duplex extension along a single stranded template. The cycles comprise steps of extension, ligation, and, preferably, cleavage. In certain embodiments the methods make use of extension probes containing phosphorothiolate linkages and employ agents appropriate to cleave such linkages. In certain embodiments the methods make use of extension probes containing an abasic residue or a damaged base and employ agents appropriate to cleave linkages between a nucleoside and an abasic residue and/or agents appropriate to remove a damaged base from a nucleic acid. The invention provides methods of determining information about a sequence using at least two distinguishably labeled probe families. In certain embodiments the methods acquire less than 2 bits of information from each of a plurality of nucleotides in the template in each cycle. In certain embodiments the sequencing reactions are performed on templates attached to beads, which are immobilized in or on a semi-solid support. The invention further provides sets of labeled extension probes containing phosphorothiolate linkages or trigger residues that are suitable for use in the method. In addition, the invention includes performing multiple sequencing reactions on a single template by removing initializing oligonucleotides and extended strands and performing subsequent reactions using different initializing oligonucleotides. The invention further provides efficient methods for preparing templates, particularly for performing sequencing multiple different templates in parallel. The invention also provides methods for performing ligation and cleavage. The invention also provides new libraries of nucleic acid fragments containing paired tags, and methods of preparing microparticles having multiple different templates (e.g., containing paired tags) attached thereto and of sequencing the templates individually. The invention also provides automated sequencing systems, flow cells, image processing methods, and computer-readable media that store computer-executable instructions (e.g., to perform the image-processing methods) and/or sequence information. In certain embodiments the sequence information is stored in a database.
Patent EP-2273675-A2 (EP)
Inventor: JOHNSON ROBERT SHAWN
IPC: H03H7/01
Filed: 2010-06-23
Abstract: An energy management system that facilitates the transfer of high frequency energy induced on an implanted lead or a leadwire includes an energy dissipating surface (161) associated with the implanted lead or the leadwire, a diversion or diverter circuit (112') associated with the energy dissipating surface (161), and at least one non-linear circuit element switch (284, 284', 284'') for diverting energy in the implanted lead or the leadwire through the diversion circuit (112') to the energy dissipating surface. In alternate configurations, the switch may be disposed between the implanted lead or the leadwire and the diversion circuit, or disposed so that it electrically opens the implanted lead or the leadwire when diverting energy through the diversion circuit to the energy dissipating surface. The non-linear circuit element switch is typically a PIN diode. The diversion circuit may be either a high pass filter or a low pass filter.
Patent EP-2255678-A2 (EP)
Inventor: POORTINGA ALBERT THIJS
IPC: A23P30/40
Filed: 2004-10-04
Abstract: A method for forming gas bubbles in a liquid product, wherein different gas beams are spouted into the product. In addition, the invention provides an apparatus for forming gas bubbles in a liquid product, in particular according to a method of one of the preceding claims, the apparatus being provided with a mixing space (3) to mix the product with gas, the apparatus comprising spouting means (1, 4) to spout different gas beams into the mixing space (3).
Patent EP-2296247-A2 (EP)
Inventor: WOBBEN ALOYS
IPC: H02J3/40
Filed: 2003-02-27
Abstract: The electrical network has at least one energy generator which uses a regenerative energy source, e.g. a wind-powered energy plant (10) coupled to a synchronous generator and a second synchronous generator (32) driven by an IC engine (30) via an electromagnetic coupler (34) allowing motor operation of the synchronous generator with the IC engine shut-down when sufficient energy is provided via the regenerative energy source. Electrical energy storage devices (12,14,18) can be incorporated for storing the excess energy provided via the regenerative energy source. An independent claim for an operating control method for an autonomous electrical network with a wind-powered energy plant is also included.
Patent EP-2292590-A2 (EP)
Inventor: KWASI OHEMENG
IPC: C07C275/28
Filed: 2004-06-25
Abstract: A compound of the formula (II):
     
wherein Q' is a prodrug moiety or a pharmaceutically acceptable salt thereof.
Patent EP-2317570-A2 (EP)
Inventor: BAWENDI MOUNGI
IPC: C09K11/00
Filed: 1998-11-10
Abstract: A coated nanocrystal capable of light emission includes a substantially monodisperse nanoparticle selected from the group consisting of CdX, where X = S, Se, Te, and an overcoating of ZnY, where Y = S, Se, uniformally deposited thereon, said coated nanoparticle charaterized in that when irradiated the particles exhibit photoluminescence in a narrow spectral range of no greater than about 60 nm, and most preferably 40 nm at full width half max (FWHM). The particle size of the nanocrystallite core is in the range of about 2 nm (20Å) to about 12.5 nm (125Å), with a deviation of less than 10% in the core. The coated nanocrystal exhibits photoluminescence having quantum yields of greater than 30%.
Patent EP-2308958-A2 (EP)
Inventor: CROWLY JOHN
IPC: C12N5/00
Filed: 2005-03-04
Abstract: The invention relates to a process for the culturing of cells by continuous perfusion culturing of a cell culture comprising cell culture medium and cells, wherein cell culture medium is added to the cell culture, the cell culture is circulated over a filter module comprising hollow fibers resulting in an outflow of liquid having a lower cell density than the cell culture and the flow within the filter module is an alternating tangential flow. Preferably, culture medium is added at a particular perfusion rate and/or biomass is removed form the culture at least once. The method is especially suitable for the culturing of aggregating cells. The invention also relates to such a process wherein a biological substance, preferably an antibody, is produced by the cells, which biological substance may be further purified in downstream processing.
Patent EP-2314311-A2 (EP)
Inventor: ZAGURY JEAN-FRANCOIS
IPC: H04L12/28
Filed: 2003-04-09
Abstract: Peptide (I) of 5-40 amino acids (aa) derived from a cytokine in which at least one aa has at least one of its atoms spaced a distance (d), evaluated from structural data, less than 5 Å from an atom of the corresponding cytokine receptor is new. Excluded are peptides from between the 2nd and 3rd Cys of RANTES and from residues 123-140 of interferon alpha . Independent claims are also included for: (1) derivatives (Ia) of (I) produced by deletion, substitution, addition, cyclization, stereochemical modification (use of D amino acids) or functionalization (e.g. acylation) of one or more aa; and (2) immunogenic compound that comprises (I) or (Ia) provided that is does not contain other cytokine epitopes and can generate antibodies that recognize the native cytokine. ACTIVITY : Immunosuppressive; Neuroprotective; Antirheumatic; Antiarthritic; Antipsoriatic; Antidiabetic; Dermatological; Antiinflammatory; Antiallergic; Antiasthmatic; Cytostatic; Anti-HIV. MECHANISM OF ACTION : Vaccine. The peptide Leu-His-Leu-Gln-Gly-Gln-Asp-Met-Glu-Gln-Gln (residues 123-132 of human interleukin-1 beta ) was attached to Lys at the N-terminus then coupled to keyhole limpet hemocyanin. The immunogen was administered (with adjuvants) to mice: 40 Microg on day 0 and 20 Microg on each of days 21 and 40. On day 60 antibodies against human IL-1 beta were measured; the enzyme-linked immunosorbent assay titer was 1.15, compared with 0.08 in unvaccinated controls. The induced antibodies were neutralizing.
Patent EP-2284111-A2 (EP)
Inventor: BARANDA PEDRO S
IPC: B66B11/00
Filed: 1999-08-23
Abstract: Elevator system, comprising 
(a) a tension member for providing lifting force to a car, the tension member, being in engagement with a rotatable traction sheave; 
(b) wherein the tension member includes a plurality of spaced metallic load carrying cords within a coating layer formed from a non-metallic material; 
(c) wherein the tension member has a ratio of width w relative to thickness t, greater than 1; and 
(d) wherein the cords each are formed of metallic strands in such a manner that the coating layer fills spaces between adjacent strands.
Patent EP-2330361-A2 (EP)
Inventor: GRUBER MICHAEL
IPC: F28F9/007
Filed: 2010-11-05
Abstract: The hot-water appliance (1) has a fastening device for fastening the hot-water appliance on a wall and a main module (20) which has a fastening area (21) for the purpose of mounting on the fastening device. The fastening device has a unit for centering the main module. The centering unit cooperates with the fastening area. The fastening device is formed of plastic or metal alloy.
Patent EP-2368981-A2 (EP)
Inventor: HELLINGA HOMME W
IPC: C12N9/22
Filed: 2006-10-18
Abstract: Rationally-designed LAGLIDADG meganucleases and methods of making such meganucleases are provided. In addition, methods are provided for using the meganucleases to generate recombinant cells and organisms having a desired DNA sequence inserted into a limited number of loci within the genome, as well as methods of gene therapy, for treatment of pathogenic infections, and for in vitro applications in diagnostics and research.
Patent EP-2357025-A2 (EP)
Inventor: GUNN EUEN T
IPC: A61K8/58
Filed: 2010-12-16
Abstract: This invention relates to a composition that is mild to the skin containing a cosmetically acceptable oil; water; a cosmetically acceptable emulsifier having an HLB of from about 1 to about 25; and a preservative comprising an organic acid selected from the group consisting of benzoic acid, p-anisic acid, sorbic acid, lactic acid, acetic acid, formic acid, oxalic acid, tartaric acid, salicylic acid and citric acid; wherein said composition has a pH less than 5 and a buffer capacity of between about 0.001 and about 0.039.
Patent EP-2391398-A2 (EP)
Title: Accessoire antimicrobien pour dispositif médical implantable
Inventor: COBIAN KENNETH E
IPC: A61L27/54
Filed: 2010-02-02
Abstract: L'invention concerne un accessoire antimicrobien qui peut comprendre un adhésif sensible à la pression et un antimicrobien mélangé dans l'adhésif sensible à la pression. Dans certains exemples, un accessoire antimicrobien peut comprendre au moins un premier domaine comprenant un adhésif sensible à la pression et un premier antimicrobien et au moins un deuxième domaine comprenant un deuxième polymère et un deuxième antimicrobien. L'accessoire antimicrobien peut être conçu pour être fixé sur un boîtier d'un dispositif médical implantable (DMI).
Patent EP-2462317-A2 (EP)
Title: Moteur à combustion interne avec cylindre et pistons en tournant excentriquement.
Inventor: DELFINI GIOVANNI
IPC: F01C1/063
Filed: 2010-07-30
Abstract: L'invention concerne un moteur à combustion interne comprenant au moins un groupe cylindres/tête (1) et au moins un groupe pistons (2), lesdits groupes tournant l'un par rapport à l'autre autour d'une première tige de rotation (A, B). Ledit au moins un groupe cylindres/tête (1) présente un premier trou central (6) à travers lequel passe la première tige de rotation (A, B), et un premier axe (9) décalé par rapport audit premier trou central (6). Ledit au moins groupe pistons (2) présente un deuxième trou central (7) à travers lequel passe la première tige de rotation (A, B), un deuxième axe (12) décalé par rapport au deuxième trou central (7), et une première fente (10) à travers laquelle passe ledit premier axe (9), dont la position est diamétralement opposée à celle du deuxième axe (12) par rapport audit deuxième trou central (7), la distance de décalage desdits premier et deuxième axes (9, 12) par rapport à un axe central traversant lesdits premier (6) et deuxième (7) trous centraux étant la même. Ledit moteur à combustion interne se caractérise en ce qu'il comprend un noyau central (3, 30) présentant un troisième trou central (8) dont le diamètre est plus petit que celui des trous centraux (6, 7), et à travers lequel passe une deuxième tige de rotation (15, 15'), une deuxième fente (11) à travers laquelle passe le premier axe (9), et une troisième fente (13) à travers laquelle passe le deuxième axe (12). En outre, la deuxième tige (15, 15') présente une section plus petite que celle de la première tige (A, B), formée en une seule pièce avec celle-ci et décalée par rapport à son axe central. Par ailleurs, la rotation dudit au moins un groupe cylindres/tête (1), dudit au moins un groupe pistons (2) et dudit noyau central (3, 30) autour desdites première et deuxième tiges de rotation (A, B; 15, 15') dans lesdits premier, deuxième et troisième trous (6, 7, 8) est excentrique et provoquée par le mouvement desdits premier et deuxième axes (9, 12) dans lesdites fentes (11, 13).
Patent EP-2459948-A2 (EP)
Title: Réfrigérateur et procédé de commande de ce dernier
Inventor: LEE NAM GYO
IPC: F25D29/00
Filed: 2010-07-15
Abstract: Linvention concerne un réfrigérateur et un procédé de commande de ce dernier. De manière plus particulière, le réfrigérateur présente un distributeur présentant une cavité pour une coupe, des portes de distributeur qui ouvrent et ferment la cavité, ainsi quun dispositif de commande de portes positionné dans le distributeur qui commande les portes du distributeur. Les portes du distributeur peuvent être automatiquement commandées pour souvrir et se fermer, ce qui améliore la propreté et laspect extérieur du réfrigérateur en réduisant laccumulation de poussière dans le distributeur pendant les périodes de non-utilisation.
Patent EP-2470166-A2 (EP)
Title: Nouvelles compositions de 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]piperazine
Inventor: HOEJER ASTRID-MARIA
IPC: A61K9/28
Filed: 2010-08-23
Abstract: La présente invention concerne des compositions pharmaceutiques de 1-[2-(2,4-diméthyl-phénylsulfanyl)- phényl]pipérazine ainsi que leurs sels d'addition d'acide, conçues de sorte que la libération ne se produise pas dans l'estomac.
Patent EP-2474017-A2 (EP)
Title: Ensemble cible comportant des fenêtres pour électrons et photons
Inventor: SCHUMACHER RICHARD
IPC: H01J35/08
Filed: 2010-08-23
Abstract: Linvention concerne un ensemble cible pour rayons X comprenant un substrat, une cible supportée par le substrat et capable de produire des rayons X lorsquun faisceau délectrons la frappe, et un boîtier formant un volume au-dessus de la cible. Le boîtier est constitué dun matériau essentiellement transparent aux électrons. Le volume est essentiellement sous vide ou rempli avec un gaz inerte.
Patent EP-2473547-A2 (EP)
Title: Polyaramide comprenant des fractions aromatiques à fonctionnalité fluorovinyléther
Inventor: DRYSDALE NEVILLE EVERTON
IPC: D01F6/90
Filed: 2010-09-01
Abstract: L'invention porte sur des polymères polyaramides comprenant des motifs répétitifs du produit de condensation d'un chlorure de diacide aromatique à fonctionnalité fluorovinyléther et d'une diamine aromatique. L'invention porte également sur des procédés de préparation de ces polymères polyaramides. Les polymères de la présente invention sont utiles en tant que fibres à haute résistance ou feuilles minces coulées en solution, présentant une sensibilité superficielle réduite aux huiles.
Patent EP-2478278-A2 (EP)
Title: Système et procédé pour régulateur d'oxygène adaptable doté d'un dispositif de commande électronique
Inventor: SHARMA H K ANURAG
IPC: F16K17/36
Filed: 2010-08-19
Abstract: La présente invention concerne un système et un procédé pour régulateur d'oxygène adaptable doté d'un dispositif de commande électronique. Dans un mode de réalisation, un système de régulateur d'oxygène comporte un dispositif de commande électronique qui inclut une mémoire non-volatile destinée à stocker un premier point de référence. Ledit dispositif de commande électronique comprend également un capteur de pression conçu pour produire des données relatives à la pression de la cabine pressurisée d'un aéronef. Ledit dispositif de commande électronique comporte en outre une unité de commande logique destinée à produire un signal de commande par le biais du traitement du premier point de référence et des données relatives à la pression. En outre, cette unité de commande électronique comprend un actionneur rotatif destiné à produire un déplacement rotatif sur la base d'un signal de commande. Par ailleurs, le système de régulateur d'oxygène comprend un dispositif de régulation de la dilution d'oxygène, couplé à ladite unité de commande électronique et conçu pour commander l'approvisionnement en oxygène et le flux d'air de dilution provenant de la cabine pressurisée de l'aéronef, sur la base du signal de commande.