baber/WOPTO huggingface dataset:
Patent CA-2379086-A1 (CA)
Inventor: BREIPOHL GERHARD
IPC: A61P9/10
Filed: 2000-07-08
Abstract: The present invention relates to ethyl (2S)-2-(naphthalene-1-sulfonylamino)-3-(4-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)ethyl)benzoylamino)propionate hemifumarate of formula (I), and to a process for its preparation comprising react-ing 4-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)ethyl)benzoic acid or a derivative thereof and ethyl (2S)-3-amino-2-(naphtha-lene-1-sulfonylamino)propionate. The compound of formula (I) is a valuable pharmaceutical which can be used, for example, in the treatment or prophylaxis of diseases which can be influenced by inhibiting the vitronectin receptor, in particular of bone diseases such as osteoporosis. The invention furthermore relates to chemical intermediates useful for the preparation of the compound of formula (I).
Patent CA-2379497-A1 (CA)
Inventor: DALLAS L MURRAY
IPC: E21B33/04
Filed: 2002-03-28
Abstract: A slip spool for selectively supporting or snubbing a tubing string suspended in a wellbore can be mounted to a wellhead. The slip spool has an axial passage to be aligned with the wellbore and at least two radial passages extending through a side wall of the slip spool and communicating with the axial passage. At least two slip blocks are slidably supported within the respective radial passages. The slip spool further includes actuators for moving the respective slip blocks between an extended position in which they engage a component in the tubing string that provides a weight-bearing shoulder, and a retracted position in which the slip blocks clear the axial passage of the slip spool. The slip spool facilitates live well service operations and eliminates scoring of an exterior surface of the tubing.
Patent CA-2385048-A1 (CA)
Inventor: KLETT JAMES W
IPC: C04B35/83
Filed: 2000-09-20
Abstract: A thermally conductive, pitch based foam composite having a particulate content. The particulate alters the mechanical characteristics of the foam without severely degrading the foam thermal conductivity. The composite is formed by mixing the particulate with pitch prior to foaming.
Patent CA-2385907-A1 (CA)
Inventor: SNUTCH TERRANCE P
IPC: C12N1/16
Filed: 2000-10-13
Abstract: On a démontré qu'une séquence d'acides aminés spécifique, située du côté proximal de la terminaison carboxy des canaux ioniques de type P/Q régule, en se liant avec la protéine Homer, l'expression du gène codant pour la syntaxine-1A. Cette région du canal ionique du calcium du type P/Q comprend des peptides qui peuvent être utilisés pour l'identification de composants modulateurs du système nerveux central.
Patent CA-2387401-A1 (CA)
Title: Compositions, methods and systems for the production of enediynes
Inventor: FARNET CHRIS M
IPC: C07D491/08
Filed: 2002-05-21
Abstract: Five protein families cooperate to form the enediyne ring structure, also referred to as the warhead structure, that characterizes enediyne compounds. This divisional application is directed to one of the five protein families, namely the polyketide synthase protein family (PKSE). The invention of the divisional application relates to members of the PKSE family and to nucleic acids encoding members of the PKSE family. The invention of this divisional application also relates to expression vectors and host cells containing the nucleic acids, methods of making a polypeptide of the PKSE family, and methods of identifying enediyne biosynthetic gene clusters and enediyne producing organisms using the nucleic acids and polypeptides of the invention. The invention further relates to use of the nucleic acids and polypeptides to design new enediyne compounds.
Patent CA-2388868-A1 (CA)
Inventor: GAO YOUHE
IPC: A61K48/00
Filed: 2000-10-06
Abstract: The present invention provides both a method and means for regulating angiogenesis within living cells, tissues, and organs in-situ. The regulatio n is performed using native PR-39 peptide or one of its shorter-length homolog , for interaction with such proteasomes as one present in the cytoplasm of viable cells. The result of PR-39 peptide interaction with proteasomes is a decrease in the intracellular degradation of active peptides such as HIF- 1.alpha. and a consequential stimulation of angiogenesis in-situ.
Patent CA-2392008-A1 (CA)
Title: Mode-selective facet layer for pump laser
Inventor: SALVATORE RANDAL A
IPC: H01S5/10
Filed: 2000-11-17
Abstract: A semiconductor pump laser comprises a ridge waveguide electro-optical structure, which converts a ridge injection current into light and an integrated wavelength selective facet reflector. This reflector controls the  longitudinal modal operation of the pump laser. Specifically, the reflector comprises a first reflective structure for reflecting light to return throug h the ridge waveguide electro-optical structure. A second reflective structure  provides wavelength-selective reflectivity when operating in combination wit h the first reflective structure. In other words, the phase of light reflected  from the first and second reflective structures is such that the net reflectivity of the facet is wavelength selective, or favors certain wavelengths over other wavelengths.
Patent CA-2392532-A1 (CA)
Inventor: CHIAN BRENT
IPC: F23N5/10
Filed: 2000-11-13
Abstract: An apparatus for and method for powering a microprocessor from energy received from a fuel burner at ignition. A thermopile receives heat energy from the flame and generates electrical power to enable operation of a microprocessor.  This electrical power is converted to a higher voltage by a special low voltage DC-to-DC converter which operates shortly after ignition. The special low voltage powers a second DC-to-DC converter which in turn powers the microprocessor.
Patent CA-2392656-A1 (CA)
Inventor: YAMAMOTO AKIRA
IPC: B27K3/36
Filed: 2002-07-05
Abstract: Wooden materials are advantageously modified with the treatment of the product of co-hydrolytic condensation of (A) 100 parts by weight of an organosilicon compound having the formula:   (R1)a(OR2)b SiO(4-a-b)/2(1) wherein R1 is alkyl, R2 is alkyl, 0.75 <= a <= 1.5, 0.2 <= b <= 3 and 0.9 < a+b <= 4, and (B) 0.5-49 parts by weight of an amino-containing alkoxysilane having the formula:        R3R4NR5-SiR6n (OR2)3-n (2) wherein R3 and R4 are H or alkyl or aminoalkyl, R5 is a divalent hydrocarbon group, R6 is alkyl, and n is 0 or 1, or a partial hydrolyzate thereof in the presence of an organic acid or inorganic acid.
Patent CA-2395297-A1 (CA)
Title: Ink container for reliable electrical and fluidic connections to a receiving station
Inventor: STURGEON SCOTT D
IPC: B41J2/175
Filed: 2001-01-31
Abstract: The present disclosure relates to a replaceable ink reservoir (12) for installation into a printing system (10) that has a moveable carriage (20) for repositioning a printing portion (16) relative to print media (22). The replaceable ink reservoir (12) includes an ink reservoir (12) that does not have an integral printing portion (16). Also included is an electrical storage device (80) for storing information. The installation of the ink reservoir (12) into the moveable carriage (20) establishes both fluid communication between the ink reservoir (12) and the moveable carriage (20) and establishes electrical continuity between the electrical storage device (80) and the moveable carriage (20).
Patent CA-2395676-A1 (CA)
Inventor: ROSEN CRAIG A
IPC: C12Q1/68
Filed: 2001-01-17
Abstract: L'invention concerne de protéines, plus précisément, des molécules isolées d'acide nucléique codant de nouveaux polypeptides. Elle concerne de nouveaux polypeptides et des anticorps qui lient ces polypeptides, ainsi que des vecteurs, des cellules hôtes, et des procédés de recombinaison et de synthèse destinés à produire des polynucléotides humains et/ou des polypeptides et des anticorps. L'invention concerne également des procédés de diagnostic et thérapeutiques servant à diagnostiquer, à traiter, à prévenir et/ou à pronostiquer des troubles relatifs à ces nouveaux polypeptides. Elle concerne en outre des procédés de criblage destinés à identifier des agonistes et antagonistes desdits polynucléotides et polypeptides. Elle concerne enfin des procédés et/ou des compositions conçus pour inhiber ou renforcer la production et la fonction desdits polypeptides.
Patent CA-2396090-A1 (CA)
Title: Asymmetric synthesis of pregabalin
Inventor: RAMSDEN JAMES ANDREW
IPC: C07C255/23
Filed: 2001-01-11
Abstract: This invention provides a method of making (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (pregabalin) or a salt thereof via an asymmetric hydrogenation synthesis. Pregabalin is useful for the treatment and prevention of seizure disorders, pain, and psychotic disorders. The invention also provides intermediates useful in the production of pregabalin.
Patent CA-2396229-A1 (CA)
Title: Compliant polymeric materials formed from macromers
Inventor: WEAVER DOUGLAS
IPC: C08G64/00
Filed: 1997-09-23
Abstract: Water-soluble macromers including at least one hydrolysable linkage formed from carbonate or dioxanone groups, at least one water-soluble polymeric block, and at least one polymerizable group, and methods of preparation and use thereof are described. The macromers are preferably polymerized using free radical initiators under the influence of long wavelength ultraviolet light or visible light excitation.      Biodegradation occurs at the linkages within the extension oligomers and results in fragments which are non-toxic and easily removed from the body. The macromers can be used to encapsulate cells, deliver prophylactic, therapeutic or diagnostic agents in a controlled manner, plug leaks in tissue, prevent adhesion formation after surgical procedures, temporarily protect or separate tissue surfaces, and adhere or seal tissues together.
Patent CA-2396660-A1 (CA)
Title: Platinum and platinum alloy powers with high surface areas and low chlorine content and processes for preparing these powders
Inventor: BIBERBACH PETER
IPC: B22F9/24
Filed: 2002-08-02
Abstract: The invention provides platinum or platinum alloy powders for use in fuel cells and for chemical reactions. The powders are characterized by a high surface area and, at the same time, low chlorine contents. The powders are prepared by forming a melt which contains, as starting substances, a low melting mixture of alkali metal nitrates, a chlorine-free platinum compound and optionally chlorine-free compounds of alloying elements, the melt is then heated to a reaction temperature at which the platinum compound and the compounds of alloying elements thermally decompose to give oxides, the melt is then cooled and dissolved in water and the oxides or mixed oxides formed are converted into platinum or platinum alloy, powders by .subsequent reduction. Binary or ternary eutectic mixtures from the LiNO, - KNO3 - NaNO3 system are suitable as a low melting mixture of nitrates of the alkali metals.   Hexahydroxoplatinic-(IV)-acid is preferably used as a chlorine-free platinum compound.
Patent CA-2396790-A1 (CA)
Title: Apparatus for adhering a clamp to a hose
Inventor: COOPER RAY
IPC: B25B25/00
Filed: 2001-01-26
Abstract: An apparatus for attaching a clamp to a hose assembly incorporates precisely located mounting devices for receiving clamp tooling, cooperating hose guiding and positioning tooling which can support a hose assembly and locate a predetermined location on such hose assembly properly aligned with a clamp in the clamp tooling. An operator loads a clamp and a hose assembly into tooling, then initiate an automatic cycle which scrubs an area on the hose, places a predetermined quantity of adhesive on that area, then brings the clamp into position and presses the clamp, adhesive, and hose together holding that position for a period sufficient to allow the adhesive to set. The operator then removes the finished part and loads another clamp and hose into the tooling.
Patent CA-2398788-A1 (CA)
Title: Slow release protein polymers
Inventor: HUBBELL JEFFREY A
IPC: A61K9/14
Filed: 2001-01-29
Abstract: The invention features articles for delivery of a biologically active substance, methods for making such articles, and methods for treating an animal using the articles.
Patent CA-2400060-A1 (CA)
Title: Method for making a joint between copper and stainless steel
Inventor: POLVI VEIKKO
IPC: C22C5/08
Filed: 2001-02-21
Abstract: A method for making a joint between copper or copper alloys and austenitic steel alloys, in which method in between the junction surfaces of the object s to be joined together, there is arranged at least one intermediate layer, so  that the junction surfaces in cluding their intermediate layers are pressed together, and at least the junction area is heated in order to create a diffusion joint. In the method, there is brought a first intermediate layer (3) on the junction surface of the steel object (2) or against said surface,  mainly in order to prevent the nickel loss from the steel object (2), and at  least a second intermediate layer (4) on the junction surface of the copper object (1) or against said surface in order to activate the creation of a diffusion joint.
Patent CA-2401088-A1 (CA)
Title: Device for packaging sheet-like folded packages
Inventor: THERIAULT DOMINIC
IPC: B65B35/24
Filed: 2002-09-03
Abstract: A device for packaging sheet-like folded packages in an overlapping shingled relationship from a delivery conveyor into opened boxes without changing the direction of the flow of packages, comprises a frame, a feeder and a packer mounted on the frame for receiving the packages from the delivery conveyor at a receiving end thereof and for receiving and carrying boxes therein, respectively. The feeder includes a first conveyor for conveying packages through the feeder in a continuation of the direction of the flow and a detector for detecting each package entering the feeder. The packer includes a second conveyor for conveying transversely and downwardly the boxes adjacent to the feeder relative and opposite to the direction of the flow for packages to stack up and fill in the boxes by successively falling therein. Preferably, the feeder includes a stopper for blocking the packages from entering the feeder.  A controller counts the packages via the detector, controls the second conveyor for filling in the boxes with packages and intermittently activates the stopper upon detection of a predetermined quantity of packages.
Patent CA-2402909-A1 (CA)
Inventor: HENNINGER FRIEDRICH
IPC: A45D1/02
Filed: 2001-03-08
Abstract: Appliances for shaping hair are provided. The hair-shaping appliances may include, for example, (a) a forward and reverse stroke liquid dosing device; (b) a tubular drum constructed to contact the hair, the tubular drum having through-passages; and (c) an evaporating device comprising an evaporator chamber to which a liquid is delivered by the dosing device, the evaporating device being constructed to produce steam from the delivered liquid and to deliver the steam through the through-passages in the tubular drum to treat the hair. Excess liquid is removed from the evaporator chamber by a return stroke of the dosing device.
Patent CA-2404207-A1 (CA)
Title: Dual-acting band brake
Inventor: VAN WOUW ROB
IPC: F16D49/08
Filed: 2002-09-19
Abstract: A band brake for retarding the motion of an associated rotatable member. The brake acts to resist motion of the rotatable member through actuation of both of its ends by a cylindrical actuating member. The band is connected with and carried by actuator so as to allow the band to move with and respond in the same direction as the actuator. In doing so, greater opportunity exists for the structure connecting the band to the actuator to withstand and resist yielding upon application of force to the actuator.
Patent CA-2405061-A1 (CA)
Title: Signal de detresse destine en particulier a l'usage sur autoroute
Inventor: HIGGS JAMES ROBERT
IPC: E01F9/06
Filed: 2001-03-27
Abstract: La présente invention concerne un signal de détresse, destiné en particulier à l'usage sur autoroute, qui est composé d'un dôme autonome (1) comprenant au moins une batterie rechargeable et/ou un condensateur destinés à alimenter, lorsque le dôme est déployé, au moins un feu de détresse (7), et un circuit de commande destiné à commander, entre autres, l'activation du feu précité (7). Dans un mode de réalisation, le signal de détresse de l'invention comprend un ensemble de dômes (1) autonomes commandés par microprocesseur capables, lorsqu'ils sont déployés et activés, d'émettre un feu de détresse clignotant ou continu et aptes, lorsqu'ils ne sont pas déployés, à être rangés dans un étui chargeur (11) stocké et transporté dans un véhicule, la batterie et/ou le condensateur précités étant rechargés à partir du système électrique du véhicule.
Patent CA-2407372-A1 (CA)
Title: Low-pressure carburising method
Inventor: GOLDSTEINAS AYMERIC
IPC: C23C8/22
Filed: 2002-02-22
Abstract: The invention relates to a low-pressure carburising method comprising alternating low-pressure enrichment steps and diffusion steps in the presence of a neutral gas. During the enrichment steps, an enriching gas and neutral gas mixture is used, the proportion of the neutral gas being between 5 and 50 % by volume of the enriching gas. The enriching gas can be, for example, acetylene (C2H2).
Patent CA-2407789-A1 (CA)
Title: Benzoxazines for use in the treatment of parkinson's disease
Inventor: BOEHME THOMAS
IPC: A61P25/16
Filed: 2001-04-17
Abstract: Benzoxazines of Formula (I) wherein R1 is C1-C6 alkyl, C2-C6 alkenyl, or (CH2)nphenyl, R2 is C3-C6 alkyl, R3 is hydrogen, halo, hydroxy, alkoxy, or alkylthio, R4 is hydrogen or alkyl, or a pharmaceutically acceptable salt thereof, are useful for treating movement disorders such as Parkinson's disease.
Patent CA-2407910-A1 (CA)
Inventor: BARASH STEVEN C
IPC: C12N15/09
Filed: 2001-06-15
Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to BLyS. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant BLyS expression or inappropriate function of BLyS comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to BLyS. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant BLyS expression or inappropriate BLyS  function comprising administering to an animal an effective amount of oune or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to BLyS.
Patent CA-2408206-A1 (CA)
Title: Toilet tank flush mechanism
Inventor: HORVATH JULIUS
IPC: E03D1/14
Filed: 2002-11-05
Abstract: The invention provides an improvement to existing toilet tank flappers, designed to conserve water. The system includes a nested compound actuator handle attached by independent arms to a compound rubber flapper system. The minor handle component actuates a smaller concentric flapper that, though initial set-up, allows for minimal water flow with the intent of only utilizing enough water to facilitate and complete bowl water exchange. The major handle component actuates the entire flapper mechanism allowing, though initial set-up, a measured amount of tank volume to facilitate the removal of waste from the bowl. The system, by design, allows the user to initiate either operation in a single motion and without the need to provide any additional input to complete the flush cycle.
Patent CA-2412580-A1 (CA)
Title: Method and apparatus for communication a public computer network
Inventor: OGMEN MELIH
IPC: G06Q20/24
Filed: 2002-11-22
Abstract: A method of processing a credit card transaction between a seller and a buyer over a network using a credit company. The method comprises the seller sending a sender identification and a product ID to the buyer. The buyer sends a buyer ID, the seller ID, the product ID and a price to the credit company. The credit company sends a bill to the buyer: The credit company sends payment to the seller, and the seller sends the product to the buyer.
Patent CA-2414023-A1 (CA)
Title: All-fiber linear design depolarizer for all-states of polarization
Inventor: AZAMI NAWFEL
IPC: G02B6/34
Filed: 2002-12-12
Abstract: An all-fiber, all-states of polarization linear design depolarizer is provided. It is made of two polarization combiners with a 2x2 directional coupler between them. The connections between the coupler and the two polarization combiners have optical phase delays and half wave polarization rotators to make proper adjustments.
Patent CA-2414183-A1 (CA)
Title: Method and apparatus for targeting virtual objects
Inventor: BONNER ALFRED E
IPC: H04N7/173
Filed: 2001-06-19
Abstract: A method and an apparatus are used to target virtual objects to subscribers in a television delivery system. Programs are selected and virtual object locations are defined in the selected programs. The virtual objects available for targeting are categorized and the categories are correlated to subscriber information to determine the optimum targeting of the virtual objects. The virtual objects may be targeted based on individual subscriber information or on information related to groups of subscribers. When a frame of a program includes a virtual object location, a default or an alternate virtual object is displayed. The virtual object location may change over space or time. The virtual object may be interactive, and may be used to link a subscriber to a remote location, such as an Internet web site. An operations center or a cable headend may generate a group assignment plan that assigns the subscribers' television terminals to groups, based on factors such as area of dominant influence and household income. A retrieval plan is then generated that instructs the television terminals to select the desired virtual object for display. The television terminals record which virtual objects were displayed, and report this information to the cable headends and the operations center.  The reported information is used to generate billing for commercial advertisers, and to analyze viewer watching habits. The invention uses upstream data reception hardware, databases and processing hardware and software, and corresponding features in the televisions to accomplish these functions.
Patent CA-2414308-A1 (CA)
Title: Transport peptides derived from erns protein, cytotoxic rnase of ribosome-inactivating protein or a rsv g-protein and analogues thereof
Inventor: LANGEDIJK JOHANNES PETRUS MARI
IPC: A61K39/00
Filed: 2001-06-28
Abstract: The invention relates to peptides derived from or similar to the Erns~ prote in of pestiviruses for type -specific diagnosis of infection, for eliciting antibiotic activity and for transport of substances into a cell. For among others these purposes the invention provides an isolated, synthetic or recombinant protein module or functional equivalent thereof comprising an amino acid sequence that is at least 75 % identical to an amino acid sequenc e of a peptide located from at about amino acid position 194 to 220 in a pestiviral Erns~ protein.
Patent CA-2414413-A1 (CA)
Inventor: NAKATA KOUICHI
IPC: G03G15/00
Filed: 2002-12-17
Abstract: In an electrophotographic photosensitive member comprising a cylindrical support, and provided thereon a photosensitive layer and a protective layer in this order, which cylindrical support has an outer diameter of less than 30 mm, the difference between a coefficient of thermal expansion .alpha.1 measured from the top of the protective layer and a coefficient of thermal expansion .alpha.2 measured after the protective layer has been removed, ¦.alpha.1 - .alpha.2¦, is more than 5.0 × 10-7 °C-1 to less than 1.0 × 10-4 °C-1, and the modulus of elastic deformation We% measured from the top of the protective layer is more than 30% to less than 60%. Also disclosed are a process cartridge and an electrophotographic apparatus which have such an electrophotographic photosensitive member.