baber/WOPTO huggingface dataset:
Patent EP-0696352-B1 (EP)
Inventor: BOLTON WADE E
IPC: G01N33/574
Filed: 1994-04-25
Granted: 2001-12-12
Abstract: The invention provides a method for enriching a sample in tumor cells and determining the DNA ploidy and proliferative index of the tumor cells present in the sample. The method uses a pan-leukocyte monoclonal antibody conjugated to a separable substrate such as magnetic microspheres to conjugate and remove leukocytes from the sample. A fluorescently labelled monoclonal antibody specific to a tumor associated antigen or an antigen arising from the presence of the tumor and a DNA staining reagent are added to the leukocyte depleted sample. The sample is then analyzed by dual color flow cytometry to determine cells having an abnormal DNA content by gating on the fluorescently labelled cells.
Patent EP-0752886-B1 (EP)
Inventor: MOURITSEN SOREN
IPC: C07K19/00
Filed: 1994-08-25
Granted: 1998-01-28
Abstract: A novel method for utilizing the immune apparatus to remove and/or down-regulate self-proteins. The method consists in providing a self-protein analog by molecular biological means by substitution of one or more peptide fragments of the self-protein by corresponding number of peptides known to contain immunodominant foreign T-cell epitopes, said substitution being carried out so as to essentially preserve the overall tertiary structure of the original self-protein. This render the self-protein immunogenic and leads to a rapid induction of high-titered autoantibodies against the native self-proteins. The modulated self-proteins can be used to prepare vaccines against undesirable proteins in humans or animals, said vaccine being useful as therapeutics against a number of diseases, e.g. cancer, chronic inflammatory diseases such as rheumatoid arthritis and inflammatory bowel diseases, allergic symptoms or diabetes mellitus.
Patent EP-0725578-B1 (EP)
Inventor: MARMONIER GILLES
IPC: A43B5/04
Filed: 1994-10-20
Granted: 1997-11-26
Abstract: Cross country ski shoe consisting of an upper (1) integral with a sole (5) having securing and articulating means (8) on the upper part of the foot-bearing surface of the ski. Said means is located near the front end of the sole (5). The bottom side (6) of the sole (5) also comprises a second fastening means (9), arranged in the area between the heel and the metatarsophalangeal joint, capable of cooperating with a complementary fastening means arranged on the upper part of the foot-bearing surface of the ski.
Patent EP-0667420-B1 (EP)
Inventor: KUEGLER JOST-ULRICH
IPC: C09K17/12
Filed: 1995-02-14
Granted: 1997-07-02
Abstract: Process for sealing earth formations comprises: (a) adding a powdered aluminate-free gelling agent to cohesive soil with a water content in the wet region of the Proctor curve to form a homogeneous mixt.; (b) homogeneously incorporating water-glass when the gelling agent has dissolved in the soil-associated water; and (c) mechanically compacting the soil to form a barrier layer.
Patent EP-0672842-B1 (EP)
Inventor: NAKANISHI KEITA
IPC: F16D69/02
Filed: 1995-03-17
Granted: 2001-11-14
Abstract: A method for producing friction material free of pills having at least 2 mm in the shorter diameter comprising mixing a dispersion medium and a friction base containing carbon fibers having a weighted mean fiber length of at least 0.3 mm, a binder and a friction modifier to form a dispersion with a solid content concentration of 0.5 to 50 % by weight, filtering the dispersion, drying the filter cake and forming the cake. The friction material has a good coefficient of friction and is excellent in its heat resistance, wear resistance and reinforcement.
Patent EP-0755061-B1 (EP)
Inventor: DAEUMLING HOLGER DR-ING
IPC: H01F38/26
Filed: 1995-07-15
Granted: 1998-12-16
Abstract: The high to medium level voltage converter is within a metal housing Ä2Ü and consists of a magnetic core Ä4Ü that is wound with a secondary winding Ä5Ü with the ends Ä6,7Ü secured to a terminal blockÄ8Ü The secondary coil is wound with insulation and is then wound with two primary coils Ä11,12Ü having an interconnection Ä15Ü. The ends of the primary coil are coupled to terminals ÄA,NÜ. The internal space of the housing is filled with an isolating material.
Patent EP-0694503-B1 (EP)
Inventor: SCHARMANN ROLF DIPL-ING
IPC: C02F1/20
Filed: 1995-07-19
Granted: 2000-03-08
Abstract: Dissolved O2 is removed from water by means of a reducing agent, using as activator a thiazine dye of formula (I), R1, R2 = H or (cyclo)alkyl or aryl; X = halogen.
Patent EP-0704635-B1 (EP)
Title: Rolled sleeve for a plain bearing
Inventor: BACK KARL
IPC: F16C17/18
Filed: 1995-08-21
Granted: 2000-05-10
Abstract: The bush is rolled into shape from a flat strip of anti-friction material. The external profiling (3,4) is of rectangular or trapezoidal cross-section, running for the entire bush length and being evenly spaced. It includes with the lengthwise axis of the bush an angle between 1 and 30 deg. The bush can be formed by truncated conical bosses on spiral lines. Depth can be between 0.01 and 0.1 mm., and the mean length of each protrusion and recess can be the same. The length of the protrusions can be between 30 and 70 percent of the outer circumference.
Patent EP-0729330-B1 (EP)
Inventor: COOPER JOHN THOMAS
IPC: A61F13/49
Filed: 1994-11-14
Granted: 2006-07-12
Abstract: A fluid pervious web suitable for use as a topsheet on an absorbent article is disclosed. The topsheet includes a fibrous and apertured, three-dimensional, macroscopically expanded, plastic web. The fibrous and apertured, three-dimensional, macroscopically expanded, plastic web permits bodily fluids to penetrate while providing an improved, less plastic-like feel and visual aesthetics.
Patent EP-0735944-B1 (EP)
Inventor: WOHLRAB WALTER
IPC: B29C45/68
Filed: 1994-12-09
Granted: 1998-07-15
Abstract: PCT No. PCT/EP94/04090 Sec. 371 Date Apr. 23, 1996 Sec. 102(e) Date Apr. 23, 1996 PCT Filed Dec. 9, 1994 PCT Pub. No. WO95/17292 PCT Pub. Date Jun. 29, 1995A mould closing device for an injection moulding machine includes a fixed (1) and a movable (4) mould clamping plate for support of screw drives (36) which are freely rotatable in the fixed mould clamping plate (1) and axially supported in one direction and supported in spindle nuts (39) secured in the movable mould clamping plate (4). Provided for actuation of the screw drives (36) for the closing and opening stroke of the movable mould clamping plate (4) are a rotary drive (44) and a hydraulic piston-cylinder unit (45, 46) interacting with the screw drives for effecting the closing force build-up. To ensure a dimensioning of the actuating drive of the screw drives substantially in accordance with the requirements for rapid opening and closing motions while the hydraulic piston-cylinder unit maintains a high closing pressure, it is proposed to form the hydraulic piston-cylinder unit of one or more pistons and hydraulic cylinders, with the admission of pressure medium for effecting the closing pressure build-up being effected by piston-cylinder units which are driven by the screw drives via interposed pressure transmitting devices (19).
Patent EP-0740733-B1 (EP)
Title: Bump-resistant door
Inventor: BERTILSSON HANS-INGE
IPC: E05D15/38
Filed: 1995-01-17
Granted: 1999-05-19
Abstract: PCT No. PCT/SE95/00036 Sec. 371 Date Jul. 26, 1996 Sec. 102(e) Date Jul. 26, 1996 PCT Filed Jan. 17, 1995 PCT Pub. No. WO95/19486 PCT Pub. Date Jul. 20, 1995The present invention relates to a door of the type having two parallel guide rails, a plurality of guide means (10, 50), which are adapted, when the door moves, to be guided by and run along the guide rails, a plurality of neighboring door leaf panels (2), which at opposite ends are connected to the associated guide means (10) of said plurality of guide means, and a bottom panel (4) which is pivotally connected to an adjoining panel (2) of said door leaf panels and, via releasable joints, connected to two associated bottom guide means (50) among said guide means. The invention is characterized in that the two bottom guide means (50) of the bottom panel (4) are each connected to an adjoining guide means (50) of a door leaf panel (2) adjoining the bottom panel (4), by means of coupling element (60), and that said releasable joints are arranged between said coupling element (60) on one hand and said bottom panel (4) on the other hand, such that said bottom panel (4), if subjected to such load that said joint is released, can swing outwards, while said coupling elements (60) and said bottom guide means (50) are kept in position relative to the remaining guide means (10) and door leaf panels (2).
Patent EP-0745063-B1 (EP)
Inventor: CAGGIANO THOMAS JOSEPH
IPC: A61K31/50
Filed: 1995-01-25
Granted: 1999-03-24
Abstract: A compound of the following structure:   <IMAGE>   wherein, when R8=H: R1=alkyl, cycloalkyl, arylalkyl, aryl; R2=cycloalkyl, aryl, C3-C10 alkyl; X,Y=O, S(O)n, NH; Z=CHO, CO2R3, CONHR4R5, CN, COR6, H, halo, HCN, NHCONR4R5, CONR4OR5, CONR4NR5R6, 1-tetrazole, S(O)nOH, S(O)nNR3R4, C=NOH, C(=N(OH)NH2, OCONR7R6, P(O)(OR4)2, C(=N(YR3))R4, NH2, SH, OH, OS(O)2R3, C(=NYC(=O)R3)R4, C(O)CO2R3, C(O)CONR3R4, CH(OH)CO2R3, CHFCO2R3, CF2CO2R3, CH(OH)CONR3R4, CF2CONR3R4, C=NNH2, C(=NOC(=O)R3)R4, C(=NNHC(=O)R3)R4, C(=NOH)R3, C(=NNR3)R4, NHC(=O)R6 or C(O)CONH2; R3, R4, R5, R6, R7=hydrogen, alkyl, aryl, aryalkyl, cycloalkyl, or fluoroalkyl; or a compound of Structure I, as just defined, wherein: X,Y=CH2, O, S(O)n, or NH; Z and R8=CO2R3, CONR3, or R8 and Z are concatenated such that R8Z=C(O)NHNHC(O), (CH2)mC(=W), V(CH2)mC(=W), or VnCH=CH(CH2)nC(=W); where V=O, S(O)n, NH; W=O, NOH, NHNH2, NOC(O)CH3, or NNHC(O)CH3; n=0-2; and m=2-4 or pharmaceutically acceptable salts thereof, useful in the treatment of asthma, and allergic and inflammatory diseases, as well as methods of treatment and pharmaceutical compositions utilizing the same.
Patent EP-0758842-B1 (EP)
Inventor: SAXBY DAVID J
IPC: A01K61/00
Filed: 1995-02-28
Granted: 1999-10-27
Abstract: Method and apparatus for harvesting and processing zooplankton and, in particular, for harvesting and processing euphausiids for subsequent use as a feed product for early stage juvenile or larvae feed or for a food product as an additive. The euphausiids are continuously harvested from coastal waters and dewatered. The dewatered product is passed to a heat exchanger (50) to increase its temperature and, thence, to a digester (51) where a desired level of enzymatic activity is obtained. The product is then held by a surge tank (80) for subsequent transfer to a ball dryer (81) where the product is dried at a relatively low temperature without destroying the stabilized enzymes created in the digester. The digesting step may be deleted in the event the use of the product is for a food product. <IMAGE>
Patent EP-0700615-B1 (EP)
Inventor: DUPONT PIERRE
IPC: H04L1/18
Filed: 1995-02-15
Granted: 2003-11-26
Abstract: An improved method of forward error correction in a data communications system that includes receiving a data frame that includes a filler symbol, detecting an error in the data frame, replacing the filler symbol with a predetermined symbol, and determining when the error has been corrected. Detecting the error includes performing a first parity check, preferably a CRC computation that is repeated a second time, after replacing the filler symbol, to determine when the error has been corrected. When replacing the filler symbol(s) has corrected the error, an automatic retry request may be foregone thus conserving channel capacity.
Patent EP-0754121-B1 (EP)
Inventor: DARFLER STEPHEN C
IPC: B32B3/12
Filed: 1995-03-31
Granted: 2003-11-26
Abstract: Thermally conductive non-metallic honeycomb structures are provided as well as a novel co-corrugation process for their production. The thermal conductivity of the non-metallic honeycomb structures is increased by incorporating unidirectional thermally conductive fibers in the corrugated laminate sheets used to form the honeycomb. Thermally conductive fibers are integrated in the laminate sheets as a unidirectional fiber prepreg which minimizes the number of broken fibers and allows controlled directional heat conductance through the honeycomb structure.
Patent EP-0767769-B1 (EP)
Inventor: PINKOS ROLF
IPC: C07C29/141
Filed: 1995-06-16
Granted: 1998-10-07
Abstract: PCT No. PCT/EP95/02335 Sec. 371 Date Dec. 27, 1996 Sec. 102(e) Date Dec. 27, 1996 PCT Filed Jun. 16, 1995 PCT Pub. No. WO96/00203 PCT Pub. Date Jan. 4, 1996Described is a method of producing 1,4-butanediol, the method calling for 2,3-dihydrofuran to be decomposed in a single stage over a hydrogenation catalyst in the presence of water and hydrogen at a temperature of 20 to 300 DEG  C. and a pressure of 1 to 300 bar and in neutral or acid conditions.
Patent EP-0772947-B1 (EP)
Inventor: VICTORIN JOHN AXEL
IPC: H04B17/00
Filed: 1995-06-30
Granted: 2003-03-05
Abstract: In a communications system including a base station coupled to a transmission antenna by means of a transmission feeder cable, and coupled to a receiving antenna by means of a receiving feeder cable, a method and system for testing the antennas and feeder cables includes a testing apparatus located at or near the antenna end of the feeder cables. A processor located within the testing apparatus initiates tests in response to commands received from the base station by means of a digital interface, which preferably uses one or both feeder cables as a communications medium. The testing apparatus includes directional couplers for each of the feeder cables, and corresponding power detectors for measuring both forward (incident) and reverse (reflected) power. All test results may be sent back to the base station, by means of the digital interface, for further analysis and status reporting.
Patent EP-0769934-B1 (EP)
Inventor: MOORE CHRISTINE JUNE
Filed: 1995-08-18
Granted: 2003-06-04
Abstract: A mild liquid skin cleanser composition with improved lathering characteristics, comprising: an alkyl ethoxylated sulfate anionic surfactant having an average degree of ethoxylation of at least about 2.0; an amphoteric surfactant selected from the group consisting of betaine surfactants, imidazoline surfactants, aminoalkanoate surfactants, and iminodialkanoate surfactants, and mixtures thereof; an N-acylamino acid surfactant, or salt thereof, a cationic cellulose ether derivative; and from 0.2 parts to 2.0 parts by weight of a C8 to C20 fatty alcohol.
Patent EP-0767666-B1 (EP)
Inventor: LEVINE DANIEL M
IPC: A61K38/00
Filed: 1995-08-10
Granted: 2003-12-03
Abstract: L'invention concerne le traitement et la prophylaxie de la toxicité induite par l'endotoxine. Ce traitement consiste à administrer au sujet des compositions contenant du phospholipide. Les compositions sont dépourvues de protéine et de peptide, et peuvent contenir des triglycérides, d'autres lipides polaires ou neutres, des acides biliaires, ou des sels d'acides biliaires.
Patent EP-0775074-B1 (EP)
Inventor: HEKAL IHAB
IPC: B21D51/38
Filed: 1995-08-23
Granted: 2002-01-23
Abstract: Closing of a metal container and the like using a special end closure. The open end portion of a container is outwardly folded to define a supporting ledge and a seaming or curling flange for the end closure. Such flange is folded or rolled inwardly to capture an end closure including a plastic frame that defines a dispensing opening and has bonded thereto an end panel to be peeled back to allow dispensing of product. A seaming flange is folded about a peripheral portion of an outer boundary of the frame member and then the two are enfolded generally flat above the supporting ledge of the container to form an inwardly directed seam. A modified end closure comprises a molded plastic frame member which matches the configuration of a ledge portion of the container so the seaming flange and peripheral border portion of the frame member can be rolled together in an inwardly directed curl. The closing operations can be performed without axial pressure on the container wall so they can be thinner than normal. Inwardly directed seams and curls protect the plastic end closure from damage caused by closing tools because dies and/or chucks contact the flange portion of the container rather than the end closure. A seal between the inwardly turned seam or curl and the border portion of the frame member can be enhanced by applying heat during formation thereof or during retorting of the container and product.
Patent EP-0828500-B1 (EP)
Inventor: BOMBARDELLI EZIO
IPC: A61K36/00
Filed: 1995-10-10
Granted: 2004-06-02
Abstract: The invention relates to methods for preventing, inhibiting, or suppressing tumors by administering to a person in need of such treatment a therapeutically effective amount of one or more flavanolignanes, such as silymarin, silybin, silidianin, silicristin, dehydrosilybin, mixtures thereof, or extracts thereof as an antiproliferative. The invention further relates to the antitumor pharmaceutical composition includes a therapeutically effective amount of the flavanolignane selected from the group of silymarin, silybin, silidianin, silicristin, dehydrosilybin, and mixtures thereof, in combination with a different antitumor agent. In another embodiment, the pharmaceutical composition includes a therapeutically effective amount of a flavanolignane selected from the group of silidianin, silicristin, and mixtures thereof, with a pharmaceutically acceptable carrier or excipient. The compositions and method may be prepared or administered with different antitumoral agents for concurrent or sequential use for treating tumors, such as those typically found in the uterus, ovary, and breast.
Patent EP-0802850-B1 (EP)
Inventor: D HOOREN JEAN-JACQUES
IPC: B60R13/02
Filed: 1995-11-09
Granted: 2002-03-06
Abstract: La présente invention est relative à un procédé de fabrication d'un panneau de portière, notamment destiné à réaliser un élément d'habillage intérieur de carrosserie de véhicule, tel que, par exemple, un panneau de portière, comprenant au moins une couche (1), notamment thermoplastique, constituant une âme, munie d'une face intérieure (2) et d'une face extérieure (3), caractérisé par le fait que: on moule, entre deux matrices (8, 9) la couche âme (1) en prévoyant localement des surépaisseurs (10), aptes à constituer des nervures (4) de renforcement réalisées dans la masse du panneau, on injecte du gaz sous pression axialement dans lesdites surépaisseurs (10) afin de pousser la matière de ladite couche âme (1) de manière à réaliser des poutres caissons tubulaires (5), on dévie latéralement ladite matière poussée lors de l'injection du gaz, on forme, dans la masse du panneau au moins une excroissance (7) avec ladite matière déviée latéralement.
Patent EP-0760259-B1 (EP)
Inventor: RUTZ GUIDO
IPC: B05B7/14
Filed: 1996-06-19
Granted: 1999-11-24
Abstract: The injection unit for powder spray coating comprises: (i) an intermediate section (30), with a passage opening (38) through it on the central axis (60) and an injection channel (46); and (ii) a front end section (32) upstream ahead of the intermediate section (30), and including an injection nozzle (65). The opening (66) jets air axially into the injection channel of the intermediate section (30), entraining coating powder through the injection channel (46). A powder induction channel (68) extends from the external end section (70) to the injector low pressure volume (50) upstream of the injection channel (46). A fluidising body (82) is attached to the end section (32).
Patent EP-0758026-B1 (EP)
Inventor: HEWITT KEITH H
IPC: B05D1/32
Filed: 1996-04-10
Granted: 2001-11-07
Abstract: A method of making coater and doctor blades for use on paper-making machinery is disclosed. A bond coating and then a wear-resistant coating are applied to one edge of an endless steel carrier strip. The strip is passed together with a masking strip continuously in only one direction through a coating zone for spraying by a plasma gun. The masking strip masks a transverse portion of the carrier strip so as to leave one edge of the latter exposed to the spray. Spraying continues for the number of passes necessary to apply desired thicknesses of the coatings to the carrier strip. <IMAGE>
Patent EP-0828935-B1 (EP)
Inventor: KLUEGL WENDELIN
IPC: F02M59/46
Filed: 1996-05-11
Granted: 2000-01-26
Abstract: L'invention concerne une soupape d'injection pour systèmes d'injection de carburant, qui comprend une aiguille d'injection (2) placée dans un corps de soupape (1), une arrivée de carburant (12), ainsi qu'un dispositif de commande. L'invention vise à ce que le taux d'injection puisse être régulable de manière précise. A cet effet, il est prévu une chambre de pression (11) qui est reliée à l'arrivée de carburant (12) par l'intermédiaire d'un étranglement primaire (14), ainsi qu'à une chambre de décharge (31) par l'intermédiaire d'un étranglement secondaire (32).
Patent EP-0832166-B1 (EP)
Inventor: JANICKI RICHARD T
IPC: B65D85/00
Filed: 1996-06-05
Granted: 2001-12-05
Abstract: A consumable container is molded from a composition comprising 40 to 90 weight % of an asphalt and 10 to 60 weight % of a polymer material, which advantageously can include a first polymer such as PP that imparts heat resistance and a second polymer such as EVA that imparts toughness and impact resistance. This molded asphalt/polymer material preferably has an unnotched Izod impact strength of at least 2 joules. The container is consumable - it can be melted along with roofing asphalt held in the container without adversely affecting the properties of the asphalt and without requiring undue mixing. The composition also can be used to reduce fumes normally emitted from a kettle of molten asphalt, e.g., as measured by a reduction of the visual opacity of the fumes by at least 25 %, a reduction of the hydrocarbon emissions of the fumes by at least 20 %, or a reduction of the total suspended particulates emissions of the fumes by at least 15 %. The container may be used, e.g., to hold roofing or paving asphalt or a recyclable petroleum-derived material, such as used motor oil. In one embodiment, the container composition may include one or more ingredients to improve the quality of paving-grade asphalt.
Patent EP-0845998-B1 (EP)
Inventor: LINDHOFER HORST
IPC: A61K39/395
Filed: 1996-08-23
Granted: 2001-11-14
Abstract: The invention concerns medicaments containing antibodies which have at least one specificity and detect the MHCII antigen of a patient to be treated. The invention further concerns antibodies with two or more specificities which detect the MHCII antigen of a patient, and diagnostic compositions containing these antibodies.
Patent EP-0861321-B1 (EP)
Inventor: LAMBALOT RALPH H
IPC: A61P31/04
Filed: 1996-10-11
Granted: 2006-05-31
Abstract: The invention pertains to isolated phosphopantetheinyl transferases, such as the E. coli acyl carrier protein synthase, which transfer a phosphopantetheinyl group onto a substrate. The enzyme can be purified from a natural source, produced recombinantly, or synthetically. Accordingly, the invention provides compositions and kits including phosphopantetheinyl transferases and host cells expressing phosphopantetheinyl transferases. The invention also provides nucleic acids encoding phosphopantetheinyl transferases and vectors comprising such nucleic acids. The invention further provides methods for phosphopantetheinylating a substrate in vitro or in vivo and methods for producing antibiotics in vitro or in vivo.
Patent EP-0859840-B1 (EP)
Inventor: DAVIS SAMUEL
IPC: A61P25/00
Filed: 1996-10-25
Granted: 2005-12-28
Abstract: A novel ligand (Efl-6) that binds the Elk subfamily of Eph receptors is identified, and methods for making the soluble Elf-6 ligand in biologically active form is described. A cDNA clone encoding this novel protein enables production of the recombinant protein, which is useful to support neuronal and other eph receptor-bearing cell populations.