baber/WOPTO huggingface dataset:
Patent JP-2684237-B2 (JP)
IPC: C07D498/06
Filed: 1990-10-03
Granted: 1997-12-03
Abstract: An optically active isomer( (R) or (S) in the 2-position) of a 1-acyloxy-2-propanol of formula <CHEM> wherein R is an aryl group, e.g. phenyl, which may have 1 or 2 substituents, preferably a p-nitrophenyl or p-bromphenyl group, is reacted with 3,4-dihydro-2H-pyran, optionally in an organic solvent, in the presence of an acidic catalyst and at a temperature of -10 to 25 DEG C, to provide a novel optically active isomer of 2-(tetrahydropyan-2-yloxy)-1-propanol of formula <CHEM> and hydrolysed, e.g. in a mixture of methanol and potassium hydroxide or in aqueous potassium hydroxide, at 0-25 DEG C, to produce optically active 2-(tetrahydropyran-2-yloxy)-1-propanol <CHEM>  which can be isolated by extraction with an organic solvent. Starting material (II) is obtainable by reacting optically active 1,2-propanediol with an acid halide RCOHal, in an organic solvent in presence of a tertiary amine, adding water after the reaction and separating the organic oily layer containing compound (II), which can be recrystallized from organic solvent to increase its optical purity and thus the purity of (I). Product (I) is obtained in optical purity of over 99%ee and is useful in synthesis of pyrido-benzoxazine antibacterial derivatives.
Patent JP-4050341-B2 (JP)
IPC: C08F4/6592
Filed: 1995-09-22
Granted: 2008-02-20
Abstract: Olefins are polymerised in contact with a catalyst system contg. (a) a solid catalytic complex based on Mg, a transition metal and a halogen obtd. by (i) reacting (I) an oxygenated organo-Mg cpd. or a halogenated Mg cpd. with (II) an oxygenated organic cpd. or a halogenated cpd. of a transition metal of Gp. IVB or VB, to give a liq. complex, and (ii) pptg. the complex by means of a cpd. of formula AlRnX3-n, to recover a solid catalytic complex, (b) an organo-metal cpd. of Gps. IA, IIA, IIB, IIIA or IVA, and (c) an electron donor used after stage (i). R = hydrocarbon gp.; X = halogen; n = less than 3.
Patent JP-2614359-B2 (JP)
IPC: C25D21/00
Filed: 1990-10-23
Granted: 1997-05-28
Abstract: The present invention resides in an anode structure as well as in an electrolytic cell utilizing the anode structure. The anode structure comprises a resilsient anode sheet (26) having an active anode surface, and a support substructure (28) for the anode sheet. The anode substructure has a predetermined configuration. Means are provided for flexing the anode sheet onto the anode substructure so that the anode sheet conforms to the configuration of the anode substructure and at the same time provides an adequate electrical junction for uniform current distribution.
Patent JP-3258790-B2 (JP)
IPC: D02G1/18
Filed: 1993-11-19
Granted: 2002-02-18
Abstract: The invention relates to a method for the manufacture of a composite yarn made of glass and organic material. According to the invention, continuous filaments of thermoplastic organic material are mingled, in the form of a ribbon, with a bundle or ribbon of glass filaments, with a speed (rate) of the thermoplastic filaments, during their penetration into the bundle or ribbon of glass filaments, greater than the rate of stretching (drawing) of the glass filaments. The invention also provides devices for the implementation of the method. <IMAGE>
Patent JP-2693191-B2 (JP)
IPC: C07C229/00
Filed: 1988-11-18
Granted: 1997-12-24
Abstract: The present invention relates to a new two-component pharmaceutical formulation of melphalan in which the two components comprise     a) freeze-dried mephalan hydrochloride and b) a solvent-diluent comprising a citrate, propylene glycol and ethanol. Substantially pure melphalan, substantially pure melphalan hydrochloride and methods for preparing them are also described.
Patent JP-2717825-B2 (JP)
IPC: C12N15/00
Filed: 1988-12-02
Granted: 1998-02-25
Abstract: The invention relates to new recombinant plasmids capable of replicating in Escherichia coli, which contain a complete or partial double- or single-stranded DNA sequence of a densovirus causing a densovirosis in a sensitive insect. The invention also relates to the complete sequence of the viral genome of Junonia Densovirus and to the plasmid containing this sequence, designated pBRJ. The invention also relates to the use of these new plasmids in biological control and to insecticidal formulations containing them.
Patent JP-2749910-B2 (JP)
IPC: H02J7/14
Filed: 1989-11-30
Granted: 1998-05-13
Abstract: A control arrangement (10) for an electrical charging system for selectively connecting alternator means (18) producing charging current at each of six outputs (22,26,30,22 min ,26 min ,30 min ) to the output of a first battery (34) and the output of a second battery (46) serially connected to the first battery (34), comprises a plurality of switchable full wave bridge rectifiers (78) for connecting each of the alternator outputs to the second battery output (50) so that the second battery (46) is charged. The rectifiers (78) are switchably connectible to the first battery output (38) so that the first battery (34) is charged. The arrangement also includes a switching circuit (74) for switching first one, and then the next of each of the switchable circuits as the voltage across the first battery (34) is increasingly less than the voltage across the second battery (46) so that the rate of charging of the first battery (34) is determined by the amount the voltage across the first battery (34) is less than the voltage across the second battery (46).
Patent JP-3119917-B2 (JP)
IPC: G01J3/28
Filed: 1991-12-03
Granted: 2000-12-25
Abstract: The transparent support element (2) of a diode line spectrometer having a concave grating (1) is designed as a biconvex lens, and the diode line (3) is arranged at a distance (d) from the second convex surface (22) opposite the concave grating (1). The radii (r1, r2) of curvature preferably differ only slightly. Simplified production and adjustment are enabled in conjunction with good optical correction. 
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Patent JP-H0655126-B2 (JP)
IPC: C12M3/00
Filed: 1989-12-19
Abstract: PURPOSE:To obtain a circulating culture device capable of effectively culturing a plant cell, tissue or fine algae, etc., by constituting the circulating culture device so as to carry out air stirring and light irradiation using a helical tube structure part provided in a part of circular culture tank for circulating culture liquid containing cells to be cultured. CONSTITUTION:In the above-mentioned helical tube structure part 2A, cells to be cultured in culture medium passing through the structure part 2A are irradiated with light from a light source 10 provided in the inner circumference part and/or outer circumference part and simultaneously the culture medium is stirred by blowing a gas such as O2 or CO2 from a gas blowing port provided in the lower part of the structure part 2A and, at the same time, foam is continuously raised in the inside of a tube. Thereby the cells to be cultured are stirred without precipitating the cells in the inside of the tube. Consequently, light can be uniformly and sufficiently irradiated to the cells. Moreover, physical stress of the cells suffered by the stirring is reduced and the cells can be efficiently reared and proliferated, and further, the secondary metabolites can be produced in high yields.
Patent JP-2718866-B2 (JP)
IPC: B65G59/02
Filed: 1992-12-22
Granted: 1998-02-25
Abstract: In order to pick up any desired packets, especially heavy packets, a pick-up device is provided with a pick-up table (1) and a pick-up auxiliary device (6). The pick-up table (1) has, at its front end, a roller-like pick-up member (5) which interacts with the end face of the packet (12) to raise the latter. In addition, the pick-up auxiliary device (6) acts on the upper side of the packet, specifically at its end opposite to the end face, and exerts a backward-directed horizontal force (B). As a result, a torque is generated which assists the raising of the packet and facilitates the picking-up thereof. 
<IMAGE>
Patent JP-H0830003-B2 (JP)
IPC: A61K9/08
Filed: 1985-01-24
Abstract: A method for reducing sensory nerve activity in a hypersensitive tooth and for desensitizing hypersensitive dentin involves applying to the surface of exposed dentin of a subject's tooth a potassium salt selected from the group consisting of potassium bicarbonate and potassium chloride in an amount effective to reduce sensory nerve activity and to desensitize hypersensitive dentin of hypersensitive teeth. In the presently preferred embodiment of the invention, potassium bicarbonate is the potassium salt and is applied in a formulation, for example, an aqueous solution containing from about 1.0 to about 360.0 mg of potassium bicarbonate per ml of solution.
Patent JP-3488456-B2 (JP)
IPC: A61P27/02
Filed: 1991-10-30
Granted: 2004-01-19
Abstract: The present invention concerns 2-decarboxyl-2-aminoalkyl derivatives of naturally occurring and synthetic prostaglandins, N-substituted derivatives, ester prodrugs and homologues of such compounds that are potent ocular hypotensives, and are particularly suitable for the management of glaucoma.
Patent JP-4037903-B2 (JP)
IPC: G01D5/38
Filed: 1995-05-25
Granted: 2008-01-23
Abstract: The apparatus disclosed herein employs a grating (13) which concentrates light at a preselected wavelength into the positive (33) and negative (35) first orders while minimizing the zeroth order (31). The grating (13) is illuminated with monochromatic light of the selected wavelength and a poly-phase periodic detector (25) has its sensing plane spaced from the grating a distance less than   <IMAGE>   where W is the width of the illuminated region of the grating. The period of the poly-phase detector is equal to P/2 so that each detector element (51) or phase responds principally to the natural interference between the positive and negative first orders without requiring magnification or redirection of the diffracted light. Preferably, the distance of the sensing plane from the grating (13) is greater than   <IMAGE>   so that the detector response does not include substantial components from diffraction orders higher than the first. Various embodiments of the invention are described including a wavefront compensation approach which greatly increases design freedom in the selection of grating and detector characteristics in implementing the present invention in practical and manufacturable devices.
Patent JP-H0660108-B2 (JP)
IPC: A61K47/22
Filed: 1990-12-19
Abstract: PCT No. PCT/EP90/02250 Sec. 371 Date Aug. 2, 1991 Sec. 102(e) Date Aug. 2, 1991 PCT Filed Dec. 19, 1990 PCT Pub. No. WO91/08765 PCT Pub. Date Jun. 27, 1991.Stabilized compositions containing a non-glycosylated human tissue type plasminogen activator derivative are disclosed. The derivative is referred to as K2P pro. The composition has enzymatic activity of at least 1.1 mU/ml, a pH of from 4.5 to 6.5, and contains citrate as well as at least one of a variety of different compounds.
Patent JP-2695042-B2 (JP)
IPC: C07C17/20
Filed: 1990-01-03
Granted: 1997-12-24
Abstract: This invention provides an improved process for the manufacture of 1,1,1,2-tetrafluoroethane by the reaction of HF and trichloroethylene in the presence of a catalyst to form a mixture comprising 2-chloro-1,1,1-trifluoroethane and 1,1,1,2-tetrafluoroethane and, optionally, other organic by-products. The improvement resides in conducting the reaction in a single reaction zone while recovering the 1,1,1,2-tetrafluoroethane from the mixture and recycling the 2-chloro-1,1,1-trifluoroethane and, optionally, other organic by-products from the mixture to the reaction along with trichloroethylene and HF.
Patent JP-3269636-B2 (JP)
IPC: C07D221/16
Filed: 1998-06-15
Granted: 2002-03-25
Abstract: Compounds of the following formula useful for inhibiting Ras function and therefore inhibiting or treating the abnormal growth of cells are disclosed: or an N-oxide thereof, or a pharmaceutically acceptable salt or solvate thereof, wherein: R and R2 are halo; R1 and R3 are H and halo, provided that at least one of R1 and R3 is H; X is N, CH or C, when the double bond is present at the C-11 position; R4 is=O, -NHOH, -N=NHR6, -N=NHSO2R6, -N=NHCOR6, -N=NHCONH2, -N=NHCOCONH2, (H, OH), (H, -OR6), (H, -OCOR6), (H, OSO2R6) or -E-(CH2)n1-G-, wherein n1 is 1 to 5, and E and G are O, S or N, and are joined to the same carbon to form a cyclic structure; R5 is H, lower alkyl, or optionally substituted aryl, heteroaryl, aralkyl, heteroaralkyl or heterocycloalkyl-alkyl; R6 is lower alkyl or optionally substituted aryl, heteroaryl, aralkyl, heteroaralkyl or heterocycloalkyl-alkyl; R7, R8 and R9 are independently selected from the group consisting of H, lower alkyl, aryl, and aralkyl; and n is 0-5.
Patent JP-4146894-B2 (JP)
IPC: A61P43/00
Filed: 1995-07-19
Granted: 2008-09-10
Abstract: PCT No. PCT/EP95/02841 Sec. 371 Date Apr. 15, 1997 Sec. 102(e) Date Apr. 15, 1997 PCT Filed Jul. 19, 1995 PCT Pub. No. WO96/03399 PCT Pub. Date Feb. 8, 1996The invention concerns componuds of formula (I), in which R1, R2, R3 and R4 have the meanings given in the description. The compounds are novel, effective PDE-inhibitors.
Patent JP-2778014-B2 (JP)
IPC: B64F1/26
Filed: 1988-07-01
Granted: 1998-07-23
Abstract: PCT No. PCT/DE88/00409 Sec. 371 Date Apr. 17, 1989 Sec. 102(e) Date Apr. 17, 1989 PCT Filed Jul. 1, 1988 PCT Pub. No. WO89/00130 PCT Pub. Date Jan. 12, 1989.A protective facility for suppressing jet aircraft noise which has a primarily horseshoe shape for surrounding a jet aircraft. Within the horseshoe and situated to the rear of any plane within the facility is found a metal, mesh lattice which redirects exhaust gasses from the jet aircraft engines upwards. Noise from the engines, in the form of sound waves, passes through the lattice and impinges upon the facility walls; being absorbed by these walls which are covered with a sound absorbing material. At the entrance to the facility are leaves hinged to the top legs of the horseshoe which roll on curved rails. These leaves may thus be swung inwards to substantially completely enclose a plane which has been placed within the horseshoe shaped facility. The leaves are also covered with sound absorbing material to absorb and deaden noises produced at the jet engine intakes. The facility walls, including the gates, are substantially rectangular in cross-section.
Patent JP-3124294-B2 (JP)
IPC: F16K3/06
Filed: 1992-02-29
Granted: 2001-01-15
Abstract: In a valve the sealing disks in contact with one another consist of sintered silicon carbide ceramic and have on their functional surface a profile bearing percentage of at least 75% established by grinding and/or lapping and/or polishing. The mean roughness at the functional surface amounts to 0.01 to 0.1  mu m. The construction is especially suitable for a sanitary mixing faucet.
Patent JP-2552157-B2 (JP)
IPC: E04F15/024
Filed: 1987-10-22
Granted: 1996-11-06
Abstract: A modular panel, which in use is laid in a continuous two-dimensional array over a supporting sub-surface to form a hollow floor, wall or ceiling suitable for reticulating electrical, optic-fibre, hydraulic and other conduit. The panel having upper and lower duct zones each partitioned by lateral ribs and longitudinal ribs respectively. The upper duct zone being in communication with the lower duct zone by way of vertical duct sets.
Patent JP-3368379-B2 (JP)
IPC: A01G1/00
Filed: 1993-08-31
Granted: 2003-01-20
Abstract: PCT No. PCT/EP93/02353 Sec. 371 Date Feb. 15, 1995 Sec. 102(e) Date Feb. 15, 1995 PCT Filed Aug. 31, 1993 PCT Pub. No. WO94/05145 PCT Pub. Date Mar. 17, 1994Pregerminated seeds comprising desiccation tolerant emerged radicles, processes for their production, and plants produced from such seeds.
Patent JP-2939891-B2 (JP)
IPC: G01N21/75
Filed: 1990-04-27
Granted: 1999-08-25
Abstract: Analytical apparatus includes a pyroelectric or other thermo-electric transducer element (10) in strip form. Thin film electrodes (12, 14) are provided and one or more dots of reagent (16) are deposited on the transducer surface. A small amount of biological or other sample is deposited over the reagent dots which undergo selective colorimetric changes. The transducer is illuminated from below by LED light sources (24) and light absorption in the reagent regions is detected as microscopic heating at the transducer surface. The electrical signal output from the pyroelectric transducer is processed to derive analyte information.
Patent JP-3913773-B2 (JP)
IPC: B24C5/04
Filed: 1994-08-29
Granted: 2007-05-09
Abstract: Abrasive jet stream cutting, wherein an abrasive is suspended in a flowable jet medium (64) and projected at high velocity and pressure (75) at a workpiece (76) is substantially improved by forming the medium of a polymer having reformable sacrificial chemical bonds which are preferentially broken under high shear conditions. Projecting the medium and suspended abrasive breaks the reformable sacrificial chemical bonds while cutting. The chemical bonds will reform, permitting recycling of the medium and abrasive for reuse in the method. The jet is effective at pressures of about 14 to 80 MPa.
Patent JP-2996353-B2 (JP)
IPC: H04L12/54
Filed: 1990-05-23
Granted: 1999-12-27
Abstract: PCT No. PCT/FR90/00365 Sec. 371 Date Dec. 13, 1991 Sec. 102(e) Date Dec. 13, 1991 PCT Filed May 23, 1990 PCT Pub. No. WO91/14325 PCT Pub. Date Sep. 19, 1991.A multiple path, self-routing switching network for switching asynchronous time division multiplex data cells includes input ports (pi1, pi64 . . . ), output ports (po1, po64 . . . ) and switching elements (TSi1, TSi16 . . . ) arranged in a number of stages of interconnected switching elements, each switching element having inlets and outlets and being constructed to transfer a data cell received at one of its inlets, to one or more of its outlets, according to routing data associated with said cells. Each switching element of at least one stage of the network has at least three outlets, arranged in groups of outlets of one or more determined outlets. Using routing data associated with a data cell received at any one of its inlets, the switching element (TSi1, TSi16 . . . ) identifies a set of one or more of said groups of outlets and to transfer said received cell to an outlet of each group of outlets of the selected set.
Patent JP-3778564-B2 (JP)
IPC: B01D53/18
Filed: 1995-09-02
Granted: 2006-05-24
Abstract: A process for cooling, demonomerizing and dedusting gas from a thermoplastic polymer drier includes directing the gas, containing thermoplastic polymer dust, monomers and water, into a packed column with a packing and washing the gas with a solvent.
Patent JP-3036079-B2 (JP)
IPC: A61K31/495
Filed: 1995-09-08
Granted: 2000-04-24
Abstract: A pharmaceutical composition comprising a compound of the following general formula ÄIÜ or its salt. <CHEM>  wherein R<1> represents aryl or a heteroaromatic group. R<2> represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, hydroxyalkyl, haloalkyl, alkoxy, alkylthio, amino, monoalkylamino, dialkylamino, or phenyl. R<3> and R<4> independently represent hydrogen or alkyl or R<3> and R<4> taken together with the adjacent N atom represent a 5- through 7-membered cyclic amino group. A represents C2-10 alkylene. W represents O, S, or (CH)n (where CH may be substituted by alkyl; n is an integer of 0, 1 or 2). X, Y, and Z may be the same or different and each represents CH (which may be substituted by alkyl), or N. Provided, however, that the case in which X, Y, and Z concurrently represent CH is excluded. The compound of the invention has excellent neuronal death inhibitory activity and is useful as a therapeutic drug for cerebrovascular diseases.
Patent JP-3031712-B2 (JP)
IPC: F01N13/02
Filed: 1992-06-10
Granted: 2000-04-10
Abstract: PCT No. PCT/GB92/01035 Sec. 371 Date Dec. 10, 1993 Sec. 102(e) Date Dec. 10, 1993 PCT Filed Jun. 10, 1991 PCT Pub. No. WO92/22734 PCT Pub. Date Dec. 23, 1992.A method is described for reducing the total emissions during cold starts from an engine burning a hydrocarbon fuel and having an afterburner arranged upstream of a catalytic converter. The method comprises the steps of: (i) adding an excess of fuel to the engine combustible charge and adding air to the engine exhaust gases immediately after the engine has first fired to assure the presence in the exhaust/air mixture of sufficient concentrations of hydrogen and oxygen to permit the resulting exhaust/air mixture to be ignitable and to burn with a steady flame in the afterburner while the latter is at a temperature close to the ambient temperature, and (ii) igniting the exhaust/air mixture in the afterburner immediately after the engine has first fired. In the preferred embodiment of the invention, the excess fuel and/or the additional air are regulated after ignition has occurred in the afterburner to maintain a steady flame in the afterburner until at least part of the matrix of the catalytic converter has reached its light off temperature.
Patent JP-3325887-B2 (JP)
IPC: H01S3/10
Filed: 1991-07-18
Granted: 2002-09-17
Abstract: PCT No. PCT/GB91/01193 Sec. 371 Date Jan. 12, 1993 Sec. 102(e) Date Jan. 12, 1993 PCT Filed Jul. 18, 1991 PCT Pub. No. WO92/02061 PCT Pub. Date Feb. 6, 1992.An optical fibre amplifier (50) comprises a SiO2-Al2O3-GeO2 single-mode optical fibre (52) doped with Er3+. It is pumped by 1.55  mu m and 1.47  mu m optical sources (54 and 56) whose optical outputs are combined by an optical coupler (58) and are then coupled to the fibre (52) by a further optical coupler (50). A source of optical signals to be amplified (62) is also coupled to the fibre (52) by the further coupler (60). The Er3+ ions provide a three-level lasing scheme with a fluorescence peak at about 1.53  mu m. Low noise amplification of optical signals in the long-wavelength tail of the fluorescence spectrum with suppressed ASE at the fluorescence spectrums peak wavelength is obtained as follows. The 1.47  mu m pump provides some low noise amplification of the optical signal but preferentially amplifies the 1.55  mu m pump source. The resultant 1.55  mu m amplified pump signal then provides pump power to amplify the optical signal whilst suppressing ASE as it has a longer wavelength than the fluorescence peak wavelength.
Patent JP-4123526-B2 (JP)
IPC: A61B17/04
Filed: 1997-09-26
Granted: 2008-07-23
Abstract: An attachment device includes an elongate guide element which is manipulatable between a pulling position in which its longitudinal axis extends generally parallel to the pulling direction and an anchoring position in which its longitudinal axis extends transversely to the pulling direction. A connecting loop of flexible and implantable material is connected, or connectable, at one end to the guide element and at its other end is connectable to one end of the prosthetic ligament to be implanted. The loop is assembled from a fibre bundle of twisted yarn. Connecting apparatus are formed in the guide elements which permit the loop to be connected thereto. Connector structure is provided on the guide elements to permit lines to be connected to the element in order to pull the guide element, and a trailing implantation system connected thereto, through bone tunnels with the guide element orientated so that its longitudinal axis extends generally parallel to the pulling direction until the element emerges from the mount at one end of one of the tunnels, whereby the guide element is manipulatable by the lines so as to overlie the mouth and thereby anchor one end of the implantation system.