baber/WOPTO huggingface dataset:
Patent CA-2452653-A1 (CA)
Title: Silencing of gene expression by sirna
Inventor: MILNER ANNE JOSEPHINE
IPC: A61P31/16
Filed: 2002-07-17
Abstract: The present invention relates to a method of selective post-transcriptional silencing in a mammalian cell of the expression of an exogenous gene of viral origin. The method comprises introducing an siRNA construct into a mammalian cell where the siRNA construct is homologous to a part of the mRNA sequence of the exogenous gene. The invention also comprises an siRNA construct with a nucleotide sequence which is homologous to a part of the mRNA sequence of an exogenous gene of viral origin and to the use of such a construct as a medicament.
Patent CA-2454499-A1 (CA)
Inventor: CERMAK GERALD F
IPC: H04L12/56
Filed: 2003-12-30
Abstract: Serialized data from broadcast services is provided to a broadcast server for transmitting to one or more client devices. The serialized data may correspond to shared data, private data; or control data. Data is scheduled for transmission based on weighted priorities including quality of service metrics. The transmission frame is arranged according to a frame protocol that includes provisions for a table of contents indexing system for the shared data.  Packets of shared data are formatted based on criteria that is known by the particular broadcast service and corresponding application that is resident on the client device.  The client device receives the table of contents at the transport layer, and notifies applications of data that will be available in the next frame. Applications submit prioritized requests to the transport layer, requesting data in the next frame. Data is retrieved by the transport layer, and deserialized by handlers for each application.
Patent CA-2455011-A1 (CA)
Title: Bituminous froth inline steam injection processing
Inventor: GASTON LES
IPC: B01F33/40
Filed: 2004-01-09
Abstract: An inline bitumen froth steam heater system is comprised of steam injection and static mixing devices. The steam heater system heats and de-aerates an input bitumen froth without creating downstream processing problems with the bitumen froth such as emulsification or live steam entrainment. The inline bitumen froth steam heater is a multistage unit that injects and thoroughly mixes the steam with bitumen resulting in an output bitumen material having a homogenous temperature of about 190°F. The heating system conditions a superheated steam supply to obtain saturated steam at about 300°F. The saturated steam is contacted with a bitumen froth flow and mixed in a static mixer stage. The static mixers provide a surface area and rotating action that allows the injected steam to condense and transfer its heat to the bitumen froth. The mixing action and the increase in temperature of the bitumen froth results in reduction in bitumen viscosity and also allows the release of entrapped air from the bitumen froth.
Patent CA-2458929-A1 (CA)
Title: Process for preparing aripiprazole
Inventor: TSUJIMORI HISAYUKI
IPC: C07D215/227
Filed: 2003-12-18
Abstract: The present invention provides a process for preparing aripiprazole in a high purity and a high yield. According to the process of the present invention, aripiprazole is prepared by the reaction of a carbostyril compound represented by general formula (2):     (see formula 2) (wherein X is halogen atom, lower alkanesulfonyloxy group, arylsulfonyloxy group or an aralkylsulfonyloxy group), with a piperazine compound represented by formula (3):     (see formula 3) and/or a salt thereof in water, in the presence of 0.5 to 10 mol of an inorganic basic compound, per mol of the carbostyril compound (2).
Patent CA-2463028-A1 (CA)
Title: Roof bolts for use in mines, a method for their production and method for their installation
Inventor: DEVER KERRY LEE
IPC: E21D20/02
Filed: 2002-09-11
Abstract: A roof bolt comprises a shaft for insertion in a hole drilled in a mine roof and a head whereby the bolt may be rotated, the head being offset with respe ct to the longitudinal axis of the shaft so that when the bolt is rotated by means of its head the shaft is caused to describe a circle of greater diamet er than its own diameter, and where the offset is at least 2mm and not more tha n 6,30mm. Preferably the offset is from 2,50 to 4mm. The invention includes a method for the production of roof bolts which comprise a shaft for insertion in a hole drilled in a mine roof and a head whereby the bolt may be rotated, the method being characterised by being controlled so that at least 90 % of the bolts produced have their head central axis offset with respect to the longitudinal axis of the shaft by an amount of at least about 1,5mm and not more than about 0,63mm.
Patent CA-2467955-A1 (CA)
Inventor: ZIOUZENKOVA OULIANA
IPC: A61K31/11
Filed: 2002-11-07
Abstract: La présente invention concerne des compositions contenant l'enzyme lipoprotéine lipase. Ces compositions peuvent être appliquées par voie topique sur la peau d'un individu afin d'en prévenir la sécheresse ou de traiter une inflammation. L'invention concerne, de plus, l'utilisation de fibrates pour améliorer l'activité de la lipoprotéine lipase. Les fibrates peuvent être utilisés par voie orale pour traiter une inflammation ou pour activer la production d'énergie métabolique.
Patent CA-2468544-A1 (CA)
Inventor: BO YUNXIN Y
IPC: A61K31/4184
Filed: 2002-12-10
Abstract: Compounds having the general structure of the Formula (I) and compositions containing them, for treatment of various diseases.
Patent CA-2469681-A1 (CA)
Title: Combination liquid dispenser and electrochemical cell
Inventor: OPHARDT HEINER
IPC: H01M8/00
Filed: 2003-01-14
Abstract: In combination, a fluid dispenser and an electrochemical cell to produce electric energy by chemical conversion of the fluid to be dispensed. The electrical energy produced is preferably used to operate a device associated with the dispensing of the fluid as, for example, in operation of an electric pump-to-pump fluid from the reservoir. The fluid preferably is dispensed for use after dispensing in some other purpose than as a source for electrochemical energy to dispense fluid from the reservoir. For example, preferred fluid containing alcohol compounds are for use in cleaning and disinfecting.
Patent CA-2471361-A1 (CA)
Title: Lift belt and system
Inventor: METZEN HANS-DIETER
IPC: B66B7/12
Filed: 2002-12-20
Abstract: The invention comprises a lift belt (10) having a ribbed profile (25) on a pulley engaging surface. The lift belt also comprises steel tensile cords (15) within an elastomeric body. The ribbed profile engages a ribbed profile on a pulley. The lift belt exhibits increased load lifting capacity due to the increased surface area of the ribs as compared to a flat belt. The belt (10) also comprises conductive tensile cords having a resistance (Br). A change in resistance is used for measuring a belt condition as well as a belt load.
Patent CA-2471698-A1 (CA)
Inventor: VRANA JOHN J
IPC: F16B27/00
Filed: 2004-06-21
Abstract: A self attaching fastener for thick panels having a pilot and a groove in a flange portion including an inclined outer wall and a bottom wall having an inclined portion extending to the outer face of the pilot and a concave surface in the outer face of the pilot adjacent the bottom wall. A die set for various panel thicknesses each having a projecting lip including an end face and first and second inclined faces which deform the panel against the inclined bottom wall and beneath the concave surface of the pilot. And, a method of attaching the fastener to a metal panel, wherein the die lip deforms a panel against the inclined bottom wall portion adjacent the pilot portion, inwardly into the concave surface and outwardly beneath the groove outer wall.
Patent CA-2473422-A1 (CA)
Title: Preparation of 5-chlorimidazoles
Inventor: GRIFFITHS GARETH
IPC: C07D233/66
Filed: 1994-03-14
Abstract: The optionally 2-substituted 5-chloroimidazoles of the general formula <IMAGE> are novel intermediates for the preparation of antihypertensive pharmaceuticals (vasodepressants) or of herbicidally active compounds. There are described a process for the preparation of these intermediates and a novel process for the further reaction of optionally 2-substituted 5-chloroimidazoles of the general formula I in which R<1> is hydrogen to give the optionally 2-substituted 5-chloroimidazole-4-carbaldehydes of the general formula <IMAGE>
Patent CA-2474144-A1 (CA)
Title: Method for securing data traffic in a mobile network environment
Inventor: EUCHNER MARTIN
IPC: H04L29/06
Filed: 2003-01-07
Abstract: In order to secure data traffic between an external network (VN) and a terminal (EG) of a mobile telephone user coupled to the external network (VN), the terminal (EG) and a data securing device (VGK) of the external network produce a pair of private external keys (FS) by exchanging partial keys (TX, TY). According to the invention, one item of key information (W) based on at least one of the partial keys (TX, TY), and one message (RRQ) certified by the terminal (EG) by means of a first home location key (HS) of the pair of home location keys, are transmitted by the data securing device (VGK) to the home location network (HN). The certification of the message (RRQ) is verified by means of a second home location key (HS) of the pair of home location keys and a certificate (HMAChs(W)) is provided for the key information. The certificate thus provided is transmitted to the data securing device (VGK) and the pair of private external keys (FS) subject to the verification of the transmitted certificate (HMAChs(W)) is accepted in order to secure data traffic.
Patent CA-2474717-A1 (CA)
Title: Cosmetic or dermatological use of vitamin a or the esters thereof in combination with a partly methylated beta-cyclodextrin
Inventor: ARCHAMBAULT JEAN-CHRISTOPHE
IPC: A61K8/73
Filed: 2003-01-31
Abstract: The invention relates to the use of dimethylated .beta.-cyclodextrins, particularly DIMEB and RAMEB, as agents promoting the penetration of vitamin A or the cosmetically or dermatologically acceptable esters thereof into the epidermis and the retention thereof in the skin, for preparing a cosmetic or dermatological composition containing a combination of vitamin A or at least one of the cosmetically or dermatologically acceptable esters thereof and said dimethylated .beta.-cyclodextrins. The invention also relates to new cosmetic or dermatological compositions containing said combinations of dimethylated .beta.-cyclodextrins and vitamin A or vitamin A esters, particularly in the form of inclusion complexes. Also disclosed are uses of said compositions in cosmetics or dermatology.
Patent CA-2474917-A1 (CA)
Title: Granzyme b inhibitors
Inventor: WILLOUGHBY CHRISTOPHER
IPC: A61P21/00
Filed: 2003-01-31
Abstract: The present invention encompasses compounds of Formula (I) and pharmaceutically acceptable salts or hydrates thereof. The compounds are inhibitors of granzyme B and are useful for treating autoimmune and chronic inflammatory diseases. Pharmaceutical compositions and methods of use are also included.
Patent CA-2476274-A1 (CA)
Inventor: TRAN TRAN TRUNG
IPC: G16B35/10
Filed: 2003-02-10
Abstract: A method of determining common three-dimensional structural features of protein surfaces is provided, as is use of representations of these common structures in molecular database searching and in designing focussed molecular libraries. The method is particularly concerned with the analysis and representation of protein surfaces such as b-turns, loops and contact surfaces. In one form, the method identifies common locations and orientations of amino acid side-chains, simplified as C.alpha.-C.beta. vectors. In another form, the method identifies common regions of surface charge represented by grid points in three-dimensional space. Further provided are common three dimensional structural features of proteins that can be used to search molecular databases for the purposes of identifying molecules that match these common three dimensional structural features. The common three dimensional structural features can also be used to focus de novo molecular generation to produce libraries containing molecules that have these common three dimensional structural features. Libraries of these structurally-related molecules may then be produced for the purposes of drug discovery.
Patent CA-2476488-A1 (CA)
Inventor: SPEAR STANTON C
IPC: B26B27/00
Filed: 2003-02-14
Abstract: A slitting tool (50) for severing a tubular body (82) includes a body portion, extending along a first axis, joined to a nose portion extending along a second axis, the second axis extending at an angle between approximately 5 degrees and approximately 90 degrees with respect to the first axis. The nose portion includes means (60) for severing the tubular body while the body portion includes means for gripping by a hand of a user such that a wrist of the hand is in a neutral position when the means for severing is directed toward the tubular body.
Patent CA-2477202-A1 (CA)
Title: Cd40 splice variants, compositions for making and methods of using the same
Inventor: BERNSTEIN JEANNE
IPC: C12Q1/68
Filed: 2003-02-24
Abstract: Substantially pure CD40 splice variants which include unique tail sequences, fragments thereof comprising at least 10 amino acids including at least 4 amino acids of the unique tail sequence; the unique tail sequences, and homologues thereof having at least 10 amino acids and 90% identity and antibodies which bind to an epitope on such proteins are disclosed.  Pharmaceutical composition comprising such protein, antibodies, isolated nucleic acid molecule that encode such proteins and pharmaceutical composition comprising such nucleic acid molecules are disclosed. The present invention relates to recombinant expression vectors which comprise such nucleic acid molecules and host cells which comprise such recombinant expression vectors are disclosed. In vitro methods of detecting in a sample the presence and/or quantity of such proteins or transcript which encodes such proteins are disclosed as are kits and reagents for performing the methods. Methods of modulating CD40-CD154 interactions in an individual are disclosed.
Patent CA-2477605-A1 (CA)
Title: Naphtha desulfurization with selectively suppressed hydrogenation
Inventor: BRIGNAC GARLAND BARRY
IPC: C10G45/06
Filed: 2003-03-11
Abstract: Naphtha is selectively hydrodesulfurized in the presence of a sulfided, treated catalyst comprising at least a Group VIB metal catalytic component, to produce sulfur-reduced naphtha with reduced olefin loss due to saturation. The catalyst is treated with hydrogen, a selectively deactivating agent which deactivates its hydrogenation activity, and a protective agent which preserves its hydrodesulfurization activity during the treatment.
Patent CA-2479191-A1 (CA)
Inventor: YEDIDYA YAIR
IPC: E06B7/086
Filed: 2004-08-26
Abstract: An electrical louvered shutter is disclosed. The electrical louvered shutter has at least one wing with a plurality of louver slats that can be rotated bye an electrical means in order to open and to close the louvered.      Each wing of the disclosed electrical louvered shutter is made of a wing framework; a plurality of louver slats movably pivotally connected to the framework and substantially filling the interior area of the framework, a tilt rod connected eccentrically to the louver slats in order to rotate the louver slats from parallel position in relation to the framework to a perpendicular position and versus verse end en electrical motor is installed inside the framework, wherein the motor includes a mechanism that is designated to move the tilt rod.
Patent CA-2482531-A1 (CA)
Inventor: SARAVANAN NO FIRST NAME
IPC: G07F17/42
Filed: 2003-04-17
Abstract: L'invention concerne une interface de création de présentation pour distributeur automatique, qui comprend un générateur de modèles définissant un modèle de présentation avec des zones actives et des zones de description associées aux zones actives. Un générateur de zones actives communique avec le générateur de modèles pour définir des actions devant être associées aux zones actives. Un générateur de programmes communique avec le générateur de modèles et le générateur de zones actives pour générer un code de programmation définissant le modèle.
Patent CA-2484255-A1 (CA)
Title: Device for modem relay channel termination
Inventor: GROVE VINCENT T
IPC: H04L29/06
Filed: 2003-05-09
Abstract: A modem data aggregating gateway that supports modem relay functionality for permitting reliable switching of modem traffic between a VoIP network and a data packet switch Internet Protocol (IP) network, s.a. the Internet. The modem relay aggregator may receive modem data encapsulated as Voice over IP  (VoIP) data packets in accordance with a Simple Reliable Protocol Transport ((SRPT) mechanism. The packet data may be error corrected and/or decompressed before being repackaged for forwarding to the ultimate destination. In the event that the destination is itself an IP device, the modem relay aggregator may forward the packets directly over the IP network. As result, if the destination of a modem call is an IP device (such as a Web site or other Internet-enabled device) the technique eliminates two points from a processing path in which digital signal processing (DSPs) would otherwise have to perform modem protocol processing. Otherwise, minimal modem reformatting can be performed at the aggregation point.
Patent CA-2488658-A1 (CA)
Title: Solid, radiation-curing binders with reactive thinners
Inventor: FAECKE THOMAS
IPC: C09D201/00
Filed: 2004-11-29
Abstract: Powder coating binders having a glass temperature of >= 35°C  containing at least one polymer and one or more radiation-curing reactive thinners, a process for the production of these powder coating binders and their use as a component of powder coatings.
Patent CA-2491940-A1 (CA)
Inventor: JIRICNY VLADIMIR
IPC: C25B9/19
Filed: 2003-07-11
Abstract: L'invention concerne une pile pour une extraction électrolytique pourvue d'une électrode de lit fluidisé avec giclage de billes de métal en formation, séparée par un diaphragme semi-perméable et conçue pour être assemblée dans une pile située dans un dispositif modulaire.
Patent CA-2492336-A1 (CA)
Inventor: KNOX ALISTAIR JOHN
IPC: G11B20/12
Filed: 2003-07-08
Abstract: Cette invention a trait à un disque optique, comportant un ensemble de pistes principales et un ensemble de pistes alternées. Certaines, au moins, de ces pistes, principales et alternées, sont associées. Lorsqu'un lecteur CD-DA a accès à ce disque optique, il ne localise que les pistes principales. Par contre, lorsqu'un lecteur de données, de CD-ROM notamment, a accès à ce disque, des modifications apportées à la table de contenus (TOC) font que ce lecteur ne peut pas accéder à une piste principale donnée, mais qu'il peut, en revanche, accéder à sa piste alternée associée. Cette dernière peut contenir des données audio (CD-DA), correspondant ou non aux données CD-DA de la piste principale associée. Ces pistes alternées peuvent être protégées contre la copie et/ou contenir des données comprimées (non CD-DA) devant être soumises à une gestion de droits numériques.
Patent CA-2492955-A1 (CA)
Inventor: ABELLAN SEVILLA JORGE
IPC: G06F12/00
Filed: 2003-07-11
Abstract: Cette invention se rapporte à la synchronisation de bases de données. A cet effet, une première base de données (DB1) est mémorisée sur un dispositif amovible tel que notamment une carte à puce (CAR) communiquant avec un premier système (MOB). Une seconde base de données (DB2) de même nature est mémorisée dans un second système (PDA) communiquant avec le premier système. Le premier et le second système (MOB, PDA) comprennent des moyens capables de générer des objets de synchronisation définissant la dernière synchronisation de base de données qui a été effectuée entre les deux bases de données de ces deux systèmes. Après chaque étape de synchronisation de la première base de données (DB1) avec la seconde base de données (DB2), un programme externe au dispositif amovible (CAR) envoie une instruction au dispositif amovible (CAR) pour régler un objet de synchronisation dans la première base de données (DB1), cet objet de synchronisation étant également modifié dans la seconde base de données (DB2) qui a été synchronisée.
Patent CA-2493667-A1 (CA)
Inventor: NIXEY THOMAS
IPC: C07D215/38
Filed: 2003-08-08
Abstract: Cette invention concerne des composés représentés par la structure générale (I) et des compositions contenant lesdits composés permettant de traiter les douleurs inflammatoires et neurogènes aiguës, les douleurs dentaires, les céphalées générales, la migraine, la céphalée vasculaire de Horton, les syndromes vasculaires mixtes et les syndromes non vasculaires, la céphalée de tension, l'inflammation générale, l'arthrite, les maladies rhumatismales, l'arthrose, les troubles intestinaux inflammatoires, les troubles oculaires inflammatoires, les troubles de la vessie instables ou inflammatoires, le psoriasis, les problèmes de peau à composantes inflammatoires, les états inflammatoires chroniques, les douleurs inflammatoires et l'hyperalgie et l'allodynie associées, les douleurs neurogènes diabétiques, la causalgie, les douleurs persistantes sympathiques, les syndromes de désafférentation, l'asthme, la dégradation ou le dysfonctionnement du tissu épithélial, l'herpès simplex, les troubles de la motilité viscérale dans des régions du système respiratoire, génito-urinaire, gastro-intestinal ou vasculaire, les blessures, les brûlures, les réactions cutanées allergiques, le prurit, le vitiligo, les troubles gastro-intestinaux généraux, l'ulcère gastrique, les ulcères duodénaux, la diarrhée, les lésions gastriques induites par des agents nécrosants, la croissance capillaire, la rhinite vasomotrice ou allergique, les troubles bronchiques ou les troubles de la vessie.
Patent CA-2498712-A1 (CA)
Inventor: PAULY FRANCOIS-XAVIER
IPC: C08K3/00
Filed: 2005-02-28
Abstract: Method for preparing polyamide-12 powder (A) by anionic polymerization of lauryl lactam (I) dissolved in a solvent in which (A) is insoluble. Method for preparing polyamide-12 powder (A) by anionic polymerization of lauryl lactam (I) dissolved in a solvent in which (A) is insoluble. Polymerization is done in presence of (a) a catalyst or activator (II); (b) a finely divided organic or inorganic filler (III), at not over 1.5 g per kg of (I), and (c) amide R1NHCOR2 (IV), at 0.001-0.03 mole per kg (I). R1 : aryl, alkyl, cycloalkyl, R3CONH or R3O; R2 and R3 : alkyl, aryl or cycloalkyl .
Patent CA-2499124-A1 (CA)
Inventor: SCHMITT CHRISTOPHE
IPC: A23L35/00
Filed: 2003-09-26
Abstract: L'invention concerne un produit choisi dans le groupe constitué d'une mousse, d'une émulsion, d'une émulsion expansée, d'une émulsion dispersée et d'une émulsion expansée. L'interface eau-air, eau-huile ou eau-solide comprend un complexe formé instantanément par le mélange d'au moins une protéine (ou peptide) et d'au moins un polysaccharide à charge opposée ou par le mélange de deux protéines à charge opposée. Le produit selon l'invention se situe dans une gamme de pH dans laquelle l'interaction électrostatique se produit entre les deux composés à charge opposée. La quantité totale de protéines et de polysaccharide est comprise entre 0,01 et 5 % en poids.
Patent CA-2499843-A1 (CA)
Title: Novel compositions and methods for the treatment of psoriasis
Inventor: JACKMAN JANET
IPC: C12Q1/68
Filed: 2003-09-25
Abstract: La présente invention concerne des compositions contenant une nouvelle protéine ainsi que des méthodes d'utilisation desdites compositions pour le diagnostic et le traitement du psoriasis.