baber/WOPTO huggingface dataset:
Patent CA-3044259-A1 (CA)
Inventor: VACCA JOSEPH P
IPC: C07D403/14
Filed: 2017-12-01
Abstract: L'invention concerne des inhibiteurs à petites molécules pour le ciblage ou les membres de la famille des protéines IRE1. La liaison peut être directe ou indirecte. L'invention concerne en outre des procédés d'utilisation d'inhibiteurs de petites molécules IRE1 pour une utilisation dans le traitement ou la réduction du cancer chez un sujet. De plus, les inhibiteurs de petites molécules IRE1 décrits ici sont destinés au traitement du cancer, le cancer étant un cancer solide ou hématologique.
Patent CA-3044909-A1 (CA)
Title: Computer network security configuration visualization and control system
Inventor: CUMMINS JOSEPH
IPC: H04L12/26
Filed: 2017-11-21
Abstract: A computing device is configured to retrieve network security configuration information from a computer network and generate a security configuration map which readily enables a user to detect defects in the security configuration with respect to a security policy. The computing device retrieves firewall configurations from security appliances in the network which operate firewalls, and processes the firewall configurations to generate a set of corresponding standardized firewall configurations. These are processed to identify enclaves containing network nodes which are associated with respective security sensitivity values based on the security policy. The computing device monitors and detects inter-node network traffic. The computing device generates a map representing the network nodes and security appliances, the security enclaves, the respective security sensitivity values, and the network traffic flows, thereby rendering readily visible inconsistencies between the actual security configuration and traffic flows, and the security policy.
Patent CA-3047862-A1 (CA)
Title: Combinaisons d'agonistes du compose fgf21/agoniste du glp-1r ayant un rapport d'activite optimise
Inventor: GOBEL BRITTA
IPC: A61P3/04
Filed: 2017-12-22
Abstract: La présente invention concerne des combinaisons, des compositions pharmaceutiques et des molécules de fusion comprenant un composé FGF21 (facteur de croissance des fibroblastes 21) et un agoniste du GLP-1R (récepteur du glucagon-like peptide-1) ayant un rapport d'activité (agoniste du GLP-1R /composé FGF21) optimisé. L'invention concerne également leur utilisation comme médicaments, en particulier pour le traitement de l'obésité, du surpoids, du syndrome métabolique, du diabète sucré, de l'hyperglycémie, de la dyslipidémie, de la stéatohépatite non alcoolique (SHNA) et/ou de l'athérosclérose.
Patent CA-3048672-A1 (CA)
Inventor: BINDHAMMER MARKUS
IPC: B27G19/02
Filed: 2017-10-20
Abstract: The invention relates to a shielding device (1) for shielding a saw blade (3) or saw band of a sawing machine against access by an operator and against workpiece parts being thrown around, which shielding device can be attached to the sawing machine in such a way that, in a working position, the shielding device covers the saw blade (3) or saw band toward the operator. The invention is characterized by the fact that the shielding device (1) comprises a temperature monitoring unit (2), which has a temperature sensor (4) operating without contact, which, when the shielding device (1) is attached to the sawing machine and is in the working position, is directed toward the teeth of the saw blade (3) or saw band, and also a display device (5), which displays the surface temperature on the surface of the teeth of the saw blade (3), detected by the temperature sensor (4). The invention further relates to a sawing machine equipped with the shielding device.
Patent CA-3050109-A1 (CA)
Inventor: BALACHANDRAN VINOD P
IPC: C12Q1/68
Filed: 2018-01-18
Abstract: L'invention concerne des systèmes et des procédés pour déterminer la réactivité probable d'un sujet cancéreux humain à un schéma immunothérapeutique à blocage de points de contrôle. Des lectures de séquençage sont obtenues à partir d'échantillons issus du sujet et représentatifs du cancer. Un type d'antigène leucocytaire humain et une pluralité de clones sont déterminés à partir des lectures de séquençage. Pour chaque clone, une fréquence initiale Xa dans ledit au moins un échantillon est déterminée et un score de condition physique correspondant du clone est calculé, ce qui permet de calculer des scores de condition physique de clone. Le calcul de chaque score de condition physique s'effectue en identifiant des néoantigènes dans le clone respectif, en calculant un potentiel de reconnaissance pour chaque néoantigène, et en déterminant le score de condition physique correspondant du clone respectif en tant qu'agrégat de ces potentiels de reconnaissance. Une condition physique totale, quantifiant la réactivité probable du sujet au schema thérapeutique, est calculée en additionnant les scores de condition physique de la pluralité de clones.
Patent CA-3050735-A1 (CA)
Title: Apparatus and methods of packaging particulates for settling
Inventor: BIERSCHENK PATRICK JOSEPH
IPC: B65B1/22
Filed: 2018-01-30
Abstract: A vertical fill, form and seal (VFFS) apparatus for particulates that facilitates the close- packing ("settling") of the particulates such that a smaller package is needed to contain a mass of particulates in a charge to the VFFS apparatus. The former of the VFFS apparatus, and an associated film driver, move up and down synchronously and in a controlled manner. A partially formed bag, below the former, containing particulates is shaken up and down as the former moves up and down, while the packaging film travels downward continuously in the apparatus. The shaking causes the particulates to settle, and to increase in bulk density. This allows use of less packaging, and lowers use of transportation fuel. In an embodiment, an actuator is in mechanical communication with the former (and its associated film driver) to apply a vertical reciprocating force to the former.
Patent CA-3051568-A1 (CA)
Title: Truck tire stop with platform
Inventor: CLEMENT KEVIN R
IPC: B65G69/34
Filed: 2019-08-09
Abstract: An apparatus for providing a tire stop for a truck proximate to an open pit comprising a base plate having top and bottom surfaces, the base plate extending between first and second side edges, and between proximate and distal edges, an elongate horizonal stopping member extending parallel to at least one of the proximate and distal edges and supported by a plurality of vertical support brackets extending from the top surface of the base plate, wherein the plurality of vertical support brackets may be configured to position the horizontal stopping member above the top surface of the base plate with a gap therebetween; and a horizontal platform extending above the base plate along the first, second and proximate edges.
Patent CA-3055218-A1 (CA)
Inventor: LIEBENOW MICHAEL HAROLD
IPC: G06T15/00
Filed: 2018-03-16
Abstract: A computer implemented method for warping multi-field color virtual content for sequential projection includes obtaining first and second color fields having different first and second colors. The method also includes determining a first time for projection of a warped first color field. The method further includes determining a second time for projection of a warped second color field. Moreover, the method includes predicting a first pose at the first time and predicting a second pose at the second time. In addition, the method includes generating the warped first color field by warping the first color field based on the first pose. The method also includes generating the warped second color field by warping the second color field based on the second pose.
Patent CA-3055700-A1 (CA)
Title: Synthetic dna molecules for expressing a protein of interest
Inventor: LARRINUA IGNACIO MARIO
IPC: A23L25/00
Filed: 2012-04-13
Abstract: The invention provides synthetic nucleic acid sequences encoding proteins of interest that are particularly adapted to express well in plants. The claimed synthetic sequences utilize plant-optimized codons roughly in the same frequency at which they are utilized, on average, in genes naturally occurring in the plant species. The invention further includes synthetic DNA sequence for herbicide tolerance, water and/or heat stress tolerance, healthy oil modifications and for transformation marker genes and selectable marker genes are used. DNA construct and transgenic plants containing the synthetic sequences are taught as are methods and compositions for using the plants in agriculture.
Patent CA-3058220-A1 (CA)
Title: A clamp cover and method of use
Inventor: BRIGHAM GRAHAM
IPC: F16L59/10
Filed: 2019-10-10
Abstract: A pipeline clamp cover has a body and a flange. The body has a front face in sealing engagement with at least one peripheral side wall such that an enclosure having a rear opening is formed. The flange is provided in sealing engagement with a bottom edge of the at least one peripheral side wall and extends outwards away from the body.
Patent CA-3063865-A1 (CA)
Title: Packer setting device
Inventor: KENT ANTHONY
IPC: E21B23/06
Filed: 2019-12-05
Abstract: Packer setting device, comprising a tubular (10) with a plug housing (14), said plug housing having an internal, through running boring (12) with an internal wall (12a), a breakable plug (16) seated in a load ring (22) axially movable within the boring (12) between a first position in where the plug (16) is with a distance to a breaking pin (18) and a second position in where the plug (16) is forced against the breaking pin (18), said load ring (22) is resting on a shear ring (20) with an annular shear lip (20a) to prevent axial movement in the first position until the shear lip (20a) is subjected to a force higher than a predetermined force, wherein the annular shear lip (20a) of the shear ring (20) extend radially inward in the boring (12), and the breaking pin (18) is resting on the shear ring (20), and said breaking pin (18) is accommodated in a pocket (28) on an outside of the load ring (22).
Patent CA-3068805-A1 (CA)
Inventor: ISHII SEIICHI
IPC: C07C2/08
Filed: 2018-07-06
Abstract: Disclosed are: a production method for an olefin multimer, the method comprising conducting an olefin multimerization reaction in the presence of a catalyst for olefin multimerization which comprises a chromium compound (A), an amine compound (B) of general formula (1), and a compound (C) such as an organometallic compound; and the catalyst for olefin multimerization. (In general formula (1), R1 to R4 each represent a group, e.g., a hydrocarbon group; Y indicates a structure represented by CR5R6- where R5 and R6 each represent a hydrogen atom or a group; and Z is an integer of 1-10.)
Patent CA-3070736-A1 (CA)
Title: Display control apparatus and display control method
Inventor: OKUTANI YASUO
IPC: H04N7/18
Filed: 2018-11-21
Abstract: A plurality of virtual viewpoint images corresponding to positions and directions of a plurality of virtual viewpoints are displayed on an operation screen for an operation associated with the position and direction of the virtual viewpoint.  The virtual viewpoint image corresponding to the virtual viewpoint selected as a position and direction operation target among the plurality of virtual viewpoints is generated based on a plurality of captured images obtained by capturing an image capturing target region by a plurality of cameras, and is transmitted to another apparatus.
Patent CA-3070955-A1 (CA)
Inventor: PROCARIO JOHN R
IPC: B23K35/22
Filed: 2020-02-04
Abstract: The disclosed technology generally relates welding wires, and more particularly to coated welding wires. A consumable welding wire comprises a base wire comprising a steel composition and a coating comprising an iron surrounding the base wire, wherein the iron oxide has an oxygen to iron (O/Fe) ratio such that an outer surface of the welding wire has a dark gray to black color.
Patent CA-3075191-A1 (CA)
Title: Utilisation de mirtazapine dans le traitement de troubles inflammatoires, de maladies auto-immunes et de la cbp
Inventor: SHAHEEN ABDEL AZIZ
IPC: A61K31/55
Filed: 2018-09-07
Abstract: L'invention concerne l'utilisation de mirtazapine dans des procédés pour le traitement de troubles inflammatoires, d'une maladie auto-immune et de la CBP (cirrhose biliaire primitive).
Patent CA-3077947-A1 (CA)
Title: Automated pizza assembly system
Inventor: FRITZ-JUNG CATHRYN
IPC: A21C9/04
Filed: 2011-02-24
Abstract: An apparatus is provided for assembling a pizza, including a pizza sauce spreading station, a cheese spreading station and a pepperoni applying station. A robot including a stationary base and an articulating arm having a gripper attached to the end is operable to grip a pizza pan having pizza dough therein to allow said robot to move the pan throughout the pizza sauce spreading station, and to a rotary dial system including the cheese spreading station and the pepperoni applying station. The robot arm manipulates the pizza pan in the sauce spreading station and the rotary dial system manipulates the pizza pan in the cheese station and the pepperoni applying station to properly distribute the cheese and pepperoni on the pizza.
Patent CA-3078600-A1 (CA)
Title: Cabinet with pull-out shelves and related pull-out mechanism with improved guide
Inventor: TROMBETTONI ROBERTO
IPC: A47B49/00
Filed: 2018-10-04
Abstract: A cabinet (1) with a containment space (2), shelves (9) contained in the containment space (2), an access opening (3) to the containment space (2) and a moving mechanism (4) for moving the shelves (9) through said opening (3); wherein said moving mechanism (4) comprises a first arm (5) and a second arm (6), which are sustained by the cabinet (1), cantilever-style, inside the containment space (2), and rotatably about a vertical line (V), said first arm (5) and second arm (6) in turn sustaining a related shelf (9) in a condition in which it can rotate, turning about at least one vertical line (V); at least the second arm (6) of said arms (5, 6) being provided with two component segments (10, 11), converging at an interposed articulated joint (12); and control and guiding means (13) for coordination of the movement of said first arm (5) and second arm (6) which are designed to allow the shelf (9) to travel along a horizontal trajectory with variable orientation of its positioning, in such a way as to pass through the access opening (3) of said cabinet (1). The control and guiding means (13) comprise a double slider (14) and a double track (16) relative to which said double slider (14) is movable, said sliders (14) and said tracks (16) being constantly coupled to one another, and operatively positioned between said first arm (5) and second arm (6).
Patent CA-3079172-A1 (CA)
Title: Compositions and methods for gene editing for hemophilia a
Inventor: BROOKS ALAN RICHARD
IPC: A61P7/04
Filed: 2018-10-17
Abstract: Provided include materials and methods for treating Hemophilia A in a subject ex vivo or in vivo. Also provided include materials and methods for knocking in a FVIII-encoding gene in a genome, in particular the locus of albumin gene.
Patent CA-3080515-A1 (CA)
Title: Metering system for fluid delivery
Inventor: ALTOBELLI DAVID E
IPC: A61M16/00
Filed: 2004-09-27
Abstract: ABSTRACT An apparatus comprising a variable acoustic source and a microphone, both acoustically coupled to a volume having a fluid region and an air region. The apparatus also can include a processor to determine a volume of the air region based on signals received from the microphone and the variable acoustic source. A fluid valve is coupled to the processor, and is configured to allow an amount of fluid to exit the fluid region associated with the volume of the air region. An atomizer, coupled to the fluid region, is configured to aerosolize at least a portion of the fluid. Date Recue/Date Received 2020-05-08
Patent CA-3080744-A1 (CA)
Inventor: COLI TODD
IPC: E21B43/12
Filed: 2013-10-04
Abstract: The present invention provides a method and system for providing on-site electrical power to a fracturing operation, and an electrically powered fracturing system. Natural gas can be used to drive a turbine generator in the production of electrical power. A scalable, electrically powered fracturing fleet is provided to pump fluids for the fracturing operation, obviating the need for a constant supply of diesel fuel to the site and reducing the site footprint and infrastructure required for the fracturing operation, when compared with conventional systems. The treatment fluid can comprise a water-based fracturing fluid or a waterless liquefied petroleum gas (LPG) fracturing fluid.
Patent CA-3081401-A1 (CA)
Inventor: PLAXCO KEVIN
IPC: A61B5/00
Filed: 2018-10-29
Abstract: Typical electrochemical sensors measure target-induced changes in current output. Such measures of target binding are inconsistent across individual sensors, and furthermore, signal will drift over time when the sensor is deployed for long periods. These shortcomings can be avoided by the novel use of chronoamperometry to measure current decay kinetics as the indicator of target binding. Current decay lifetimes will vary in a concentration dependent manner, but remain stable across individual sensors and over time, allowing for calibration-free operation. By these methods, aptamer based electrochemical sensors and other sensor types may be deployed in vivo for extended periods of time and will provide accurate measurement of target binding without calibration.
Patent CA-3081948-A1 (CA)
Inventor: LAZZARO ANTHONY
IPC: F16M11/06
Filed: 2020-06-03
Abstract: A blade flexure assembly that includes first and second mounting structures. Two or more flexure blades are connected to and extend between the first and second mounting structures. Clamping blocks clamp the flexure blades to the mounting structures. The modular design of the assembly provides for replacing one or more of the flexure blades to adjust one or more functional aspects of the assembly.
Patent CA-3082245-A1 (CA)
Inventor: HOFFMAN KEITH A
IPC: A61F13/08
Filed: 2018-10-29
Abstract: A method for tailoring a compression garment. The compression garment comprises a first sheet and a second sheet, each having a first lateral end and a second lateral end, at least one strap for holding together the first lateral end of the first sheet and the first lateral end of the second sheet. Said at least one strap is tightenable to establish a compression level to a human limb or body part by the compression garment. The method includes: a first step of adjusting the at least one strap to be in a first position; a second step of draping the compression garment around the limb or the body part; a third step of holding the second lateral end of the first sheet and the second lateral end of the second sheet together to pull the first sheet, the second sheet and the at least one strap into contact with said limb or body part; a fourth step of marking a cutting line on one or both sheets; a fifth step of cutting the first and the second sheet along the cutting line; a sixth step of splicing together both cut ends with at least one splicing element.
Patent CA-3082817-A1 (CA)
Inventor: WHATCOTT RUSSELL B
IPC: B29C33/44
Filed: 2018-11-13
Abstract: Extractor systems (120) for extracting a flexible article of manufacture from a mold include an extraction roller (122), at least one track configured to support the extraction roller, and a trolley (126) configured to carry the extraction roller from a first side of the mold toward a second, opposite side of the mold. Molding systems include a mold and an extractor system. Methods of extracting a flexible article of manufacture from a mold include separating a first platen (102) and a second platen (104), positioning an extraction roller (122) between the separated first and second platens, engaging the article of manufacture with a row of teeth (123) positioned along the extraction roller, and rotating the extraction roller (122) to wrap the article of manufacture about the extraction roller(122).
Patent CA-3083372-A1 (CA)
Inventor: PICKERING DAREN
IPC: H04B5/00
Filed: 2018-12-07
Abstract: L'invention concerne un dispositif de communication sans fil électronique comprenant : un moyen de communication sans fil pour communiquer avec un dispositif d'initiation de communication sans fil ; un moyen pour surveiller un signal de communication reçu par le moyen de communication sans fil ; un moyen pour envoyer au moins une première valeur caractéristique relative au signal de communication reçu par le moyen de communication sans fil à au moins un autre dispositif de communication sans fil électronique ; un moyen pour recevoir au moins une autre valeur caractéristique relative à un signal de communication reçu par le ou les autres dispositifs de communication sans fil électronique ; et un moyen de traitement pour effectuer une comparaison sur la base de la première valeur caractéristique et de l'autre valeur caractéristique, le dispositif sans fil électronique étant configuré pour activer sélectivement une communication avec le dispositif d'initiation de communication sans fil sur la base du résultat de la comparaison. L'invention concerne également un système et un procédé de communication entre un dispositif de communication sans fil électronique d'une pluralité de dispositifs de communication sans fil électroniques et un dispositif d'initiation de communication sans fil qui peut lire l'un des dispositifs de communication sans fil électronique.
Patent CA-3083816-A1 (CA)
Inventor: BARROW BOYCE
IPC: F04D7/04
Filed: 2018-12-21
Abstract: In centrifugal pumps and, in particular, pumps for transferring fluids containing abrasive particles such as slurry pumps, wear of wetted areas is a major maintenance issue. The invention provides for the protection of internal surfaces vulnerable to wear from such particles by providing means for adjusting and controlling distribution of gland fluid for flushing vulnerable areas. The invention extends to a method and a retrofit kit, but provides primarily for a centrifugal pump assembly comprising an impeller rotatably mounted therein and support means operatively arranged for supporting the impeller from its suction side in sealing relationship with the housing. The sealing means may be mechanically adjustable for substantially even distribution of gland fluid to both axial sides of the impeller in the pump housing.
Patent CA-3083942-A1 (CA)
Title: Menu personalization
Inventor: KASHANI ALI HAGHIGHAT
IPC: G06Q30/02
Filed: 2018-11-28
Abstract: Provided are systems, methods, and computer-program products for generating a personalized item list. In various examples, a server computer on a network can receive a request that includes a user identifier. The computer can use the user identifier to look up a data model associated with the user identifier. The computer can further determine a geolocation, and use the geolocation to determine a list of items associated with an eatery at or near the geolocation. The computer can input the item list into the data model, for the data model to output a probability for each item, the probability indicating a likelihood that the user will select the item. The probabilities can be used to generate a personalized item list, which can be output onto the network for receipt by a computing device.
Patent CA-3084173-A1 (CA)
Title: Novel 3,5-disubstitued-3h-imidazo[4,5-b]pyridine and 3,5- disubstitued_-3h-[1,2,3]triazolo[4,5-b] pyridine compounds as modulators of protein kinases
Inventor: MUTHUPPALANIAPPAN MEYYAPPAN
IPC: C07D471/04
Filed: 2011-05-13
Abstract: The present invention provides, inter alia, compounds of formula IA, IIA and III as protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorder with them.