Patent SG-11201807614S-A (SG)
Title: Compositions and methods for treating rheumatoid arthritis
Inventor: BAUER DEBORAH
IPC: C07K16/28
Filed: 2017-03-07
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 14 September 2017 (14.09.2017) WIPO I PCT (10) International Publication Number WO 2017/155990 Al 111111111111110111011111111111010111110 01111111111111110111101111111111111110111111 (51) International Patent Classification: A61K 39/395 (2006.01) A61K 39/00 (2006.01) C07K 16/28 (2006.01) C07K 16/24 (2006.01) (21) International Application Number: PCT/US2017/021149 (22) International Filing Date: 7 March 2017 (07.03.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 16305253.3 7 March 2016 (07.03.2016) EP 16170664.3 20 May 2016 (20.05.2016) EP 16306111.2 5 September 2016 (05.09.2016) EP (71) Applicants: SANOFI BIOTECHNOLOGY [FR/FR]; 54, Rue La Boetie, 75008 Paris (FR). REGENERON PHAR- MACEUTICALS, INC. [US/US]; 777 Old Saw Mill River Road, Tarrytown, NY 10591 (US). (72) Inventors: BAUER, Deborah; c/o Sanofi, 55 Corporate Drive, Mail Code: 55A-505A, Bridgewater, NJ 08807 (US). BODDY, Alexander; c/o Sanofi, 55 Corporate Drive, Mail Code: 55A-505A, Bridgewater, NJ 08807 (US). GRAHAM, Neil; c/o Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591 (US). LIN, Yong; c/o Sanofi, 55 Corporate Drive, Mail Code: 55A-505A, Bridgewater, NJ 08807 (US). PAR- RINO, Janie; c/o Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River Road, Tarrytown, NY 10591 (US). PATEL, Rahul; c/o Sanofi, 55 Corporate Drive, Mail Code: 55A-505A, Bridgewater, NJ 08807 (US). VAN AD- ELSBERG, Janet; 420 Riverside Drive, New York, NY 10025 (US). VAN HOOGSTRATEN, Hubert; c/o Sanofi, 55 Corporate Drive, Mail Code: 55A-505A, Bridgewater, NJ 08807 (US). (74) Agents: VELEMA, James, H. et al.; Lathrop & Gage LLP, 28 State Street, Boston, MA 02109 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Publ ished: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) with sequence listing part of description (Rule 5.2(a)) W O 20 17 / 155 990 Al (54) Title: COMPOSITIONS AND METHODS FOR TREATING RHEUMATOID ARTHRITIS (57) : The present invention relates to the use of an anti-IL6 receptor antibody in monotherapy for treating rheumatoid arth- ritis and for improving the physical function and the quality of life of a subject suffering from rheumatoid arthritis.