baber/WOPTO huggingface dataset:
Patent DK-1100913-T3 (DK)
Inventor: MARCIREAU CHRISTOPHE
IPC: A61P17/02
Filed: 1999-07-21
Granted: 2009-08-24
Abstract: The present invention relates to a novel protein of the MEKK signal transduction pathway, and the gene encoding it. The invention further relates to diagnostic and therapeutic uses of the protein or the gene, and to methods of screening for agonists or antagonists of the protein, particularly with respect to MEKK activity. In particular, the invention provides a gene encoding MIF1, the MIF1 protein, and antibodies that specifically bind MIF1. MIF1 and the MIF1 gene can be used in screening assays, particularly to identify agonists and antagonists of MIF1 interaction with MEKK, and thus modulators of the MEKK signal pathway. MIF1 gene (or cDNA) can also be delivered to cells, e.g., for in vitro screening or testing, or in vivo or ex vivo for gene therapy.
Patent DK-1121448-T3 (DK)
Inventor: AMITAI HAGIT
IPC: C12N15/62
Filed: 1999-10-14
Granted: 2005-01-24
Abstract: Novel glycosylated intracellular IL-1 receptor antagonist type II (icIL-1ra-II) is expressed and secreted in mammalian cells transformed with an expression vector where icIL-1ra-II is secreted by expressing icIL-1ra-II fused to the human growth hormone signal peptide. Also disclosed are a pharmaceutical composition containing glycosylated icIL-1ra-Il as an active ingredient and a method for reducing IL-1 levels in patients having a condition involving overexpressed IL-1.
Patent ES-2228324-T3 (ES)
Inventor: THILKER LUTZ
IPC: H01H39/00
Filed: 2000-04-01
Granted: 2005-04-16
Abstract: A short-circuiting device, with a short-circuiting piston (5) driven by a gas generator (6) for electrically connecting a terminal bar (3) to a connection bar (2), is new.  A short-circuiting device has a short-circuiting piston (5) which is guided and retained in a connection bar (2) and which is driven, for electrical connection of a terminal bar (3) to the connection bar (2), by a gas generator (6) embedded in an insulating holder (7) which has a front space (31) and which is connected to the connection bar (2).
Patent ES-2208170-T3 (ES)
Inventor: FRANCHIN PIER LUIGI
IPC: B27M1/08
Filed: 2000-04-25
Granted: 2004-06-16
Abstract: A method (L) for profiling laths for parquet aligned on a tow chain (9) enclosed in the case (19) of the base (2) of a squaring machine (1) provided with a plurality of operating heads (3, 4, 5, 6, 7). The method comprises the following operations: engravings the face (L') of each lath (L) towards said chain (9) a couple of longitudinal engravings (S'; S''); millings on both lateral ribs (B', B'') of each lath (L); shaping the lateral ribs (B', B'') for the whole length making on one of said ribs (B') a male profile (M) and on the opposite rib (B'') a female profile (F). The distance (D) between said engravings (S', S'') is lower than the width (24) of said case (19), each of said engravings being obtained by a rotating tool (3'; 3''; 4'; 4'') belonging to one of said operating heads (3a, 3b, 4a, 4b) and having the rotating plane (30', 30'', 40', 40'') sloping in respect with the faces of the lath (L). <IMAGE>
Patent ES-2278559-T3 (ES)
Inventor: BASTIOLI CATIA
IPC: C08J9/12
Filed: 1995-08-03
Granted: 2007-08-16
Abstract: Biodegradable foamed articles having density comprised from 5 to 300 kg/m³ obtained by agglomeration of foamed particles having composition comprising a thermoplastic starchy material or a thermoplastic natural polymer capable of absorbing water when converted into the thermoplastic state, a thermoplastic polymer, and water.
Patent ES-2208238-T3 (ES)
Title: Aplicador para la aplicacion de un producto, y su utilizacion para la transferencia del producto a una superficie tal como la piel.
Inventor: JOULIA GERARD
IPC: A45D33/36
Filed: 2000-05-29
Granted: 2004-06-16
Abstract: Aplicador (1) para la aplicación de un producto, que comprende un elemento de prensión (2) solidario de un órgano de aplicación (4) formado por una base de sustentación (3) sobre la cual hay un soporte de aplicación (6) montado, que define una superficie de aplicación (6a) que comprende un órgano de maniobra (2, 11), previsto para modificar el perfil de la superficie de aplicación (6a), perpendicularmente a un plano medio (P) de la base de sustentación (3), caracterizado porque dicha base de sustentación está atravesada por cuando menos un paso (12), a través del cual una porción (11) del órgano de maniobra es apta para ajustar con el soporte de aplicación (6), de manera que, en respuesta a una presión ejercida por dicha porción (11) de modo sensiblemente perpendicular a la superficie de aplicación, se modifique el perfil de la citada superficie de aplicación (6a).
Patent ES-2174803-T3 (ES)
Inventor: KOCH MICHEL
IPC: A61P35/00
Filed: 2000-06-15
Granted: 2002-11-16
Abstract: 7-Oxo-2,3,7,14-tetrahydro-1H-benzo(b)pyrano(3,2-h) acridine derivatives (I), their salts with acids and bases, their isomers, N-oxides, their preparation, and pharmaceutical compositions containing them. The new compounds are of formula (I) X and Y = H, halogen, OH, SH, CN, NO2, 1-6C alkyl, alkoxy, or trihaloalkyl, amino (optionally by one or two 1-6C alkyl groups which may be substituted by alkoxy groups or by a group of formula NR7R8) or together form a methylenedioxy or ethylene dioxy group, the groups X and Y being present on either of the two adjacent benzene rings; R7 and R8 = H or 1-6C alkyl, aryl, or aralkyl; R1 = H or 1-6C alkyl; R2 = H, OH, 1-6C alkyl or alkoxy (optionally substituted by NR9R10, or by a 5-7 membered saturated or unsaturated mono- or bicyclic heterocycle having one or two hetero atoms selected from O, N, and S), alkyl carbonyloxy, or amino (optionally substituted by one or two alkyl, aryl, or aralkyl groups, an alkylcarbonyl group that may be substituted by NR7R8, a group -R11-NR9R10, an alkylene group substituted by a heterocycle, or a group -R11-CO-R12; R9 and R10 = H, or 1-6C alkyl or hydroxyalkyl; R11 = 1-6C alkylene; R12 = OH or 1-6C alkoxy; R3 and R4 = H or 1-6C alkyl; one or both of R5 and R6 = a group -O-CO-U-V, and if only one has this meaning the other represents a group Z; U = 1-8C alkylene, optionally substituted by one or more groups selected from aryl, OH, or 1-6C alkoxy; V = COOH, COOR13, OH, 1-6C alkoxy, -NR7R8, -NR7-COOR13, -NR7-CO-R13, -COR13, or CONR7R8; R13 = 1-6C alkyl optionally substituted OH, aryl, or aralkyl; Z = OH, 1-6C alkoxy, alkoxycarbonyl, alkylcarbonyloxy, arylcarbonyloxy, arylalkyl carbonyloxy, or amino optionally substituted by one or two alkyl groups
Patent ES-2321054-T3 (ES)
Inventor: BABICH JOHN W
IPC: A61K47/48
Filed: 2000-01-19
Granted: 2009-06-02
Abstract: The present invention provides novel agents for specifically targeting and detecting or treating focal sites of infection or inflammation in a subject.
Patent ES-2251366-T3 (ES)
Inventor: AZNOIAN HAROLD M
IPC: A61B1/00
Filed: 2000-01-27
Granted: 2006-05-01
Abstract: A endoscopic multiple sample biopsy forceps is disclosed having a jaw assembly with a pair of jaws connected to a pair of arms extending from a jaw housing. Each jaw has two shanks oppositely displaced from the longitudinal axis of the device to define a space in the rear of the jaw for storing collected tissue samples. The tissue storage space defined by the jaw shanks opens rearwardly into a tissue storage area defined within the housing. Each shank has a broad outwardly facing planar surface aligned with an inwardly facing planar surface on one of the pair of arms. A cam slot on each jaw shank is slidably engaged by a cam pin on one of the pair of arms. A puller member coaxially positioned in the housing and axially movable relative to the housing supports a pair of pivots, each of which pivotally engages a bore on at least one jaw shank. The puller member is attached to a drive wire coaxially positioned in a tubular shaft. Axial movement of the drive wire actuates the puller member. In response to axial movement of the puller along the longitudinal axis of the outer tube, the cam pins riding in the cam guide slots change the position relative to the fixed jaw pivot axis of the jaw, thus actuating the jaws. None of the jaw assembly elements movable relative to the device, except the jaws, are externally exposed such that they could contact targeted tissue and negatively affect tissue sampling operations. An ejector is provided to push collected samples from the tissue sample storage area.
Patent ES-2255497-T3 (ES)
Title: Composicion para despues del afeitado que contiene hidrocloruro de aluminio.
Inventor: MORRISSEY MAUREEN SULLIVAN
IPC: A61K8/26
Filed: 2000-05-22
Granted: 2006-07-01
Abstract: Una composición para después del afeitado que comprende, en peso, al menos 30% de agua, de 5 a 65% de etanol, de 0, 25 a 6% de fragancia, de 0, 25 a 5% de tensioactivo para solubilizar o emulsionar la fragancia y de 0, 5 a 1, 5% (U.S.P) de hidrocloruro de aluminio.
Patent ES-2202166-T3 (ES)
Inventor: OPHIR AVRAHAM
IPC: F04D17/10
Filed: 2000-09-08
Granted: 2004-04-01
Abstract: A method is provided for improving the performance of a heat-pump installation for making ice operating on the principle of mechanical water vapor compression. The installation comprises an evaporator-freezer chamber communicating with a compressor chamber having a centrifugal compressor unit. The method comprises a) providing a first droplet separator of the louver type between the evaporator-freezer chamber and the compressor chamber, for primary separation of the coarser droplets; b) providing a second droplet separator of the knitmesh type downstream of the first droplet separator, for secondary separation of the remaining fine spray, and c) providing a continuous or intermittent spray of a dilute solution of a highly water-soluble inorganic salt in counter-current to the vapor flow from a plurality of spray nozzles located between the first and the second droplet separators and facing the first droplet separator.
Patent ES-2231264-T3 (ES)
Title: Procedimiento y dispositivo para procesar informaciones de señalizacion en una red de telecomunicaciones.
Inventor: FREYENBERG CHRISTIAN
IPC: H04Q3/545
Filed: 2000-08-22
Granted: 2005-05-16
Abstract: Procedimiento para procesar informaciones de señalización en una red de telecomunicaciones, en el que un puesto de conmutación (5) intercambia con un equipo terminal de abonado (10) informaciones de señalización, siendo transformadas las informaciones de señalización en el puesto de conmutación (5) en al menos un mensaje, que se transmite al menos a un servidor de servicios de telecomunicaciones (9) unido con el puesto de conmutación (5), ejecutando el o los servidores de servicios de telecomunicaciones los servicios e telecomunicaciones correspondientes a los mensajes, caracterizado porque el mensaje se transmite a través de Internet a un servidor de Internet como servidor de servicios de telecomunicaciones.
Patent ES-2284528-T3 (ES)
Inventor: FRANANO NICHOLAS F
IPC: A61K31/167
Filed: 2000-09-24
Granted: 2007-11-16
Abstract: The invention provides methods to treating an obstructed biological conduit, that include administering to the conduit an agent that can degrade extracellular matrix of obstructing tissue. Particular methods include delivery of an enzyme or a mixture of several enzymes to the area or region of obstruction wherein the enzyme(s) have the capability to degrade extracellular matrix components within the obstruction thereby restoring the normal flow of transported fluid through the conduit. The invention also includes preventively dilating a section of conduit to minimize the risk of obstruction formation.
Patent ES-2194790-T3 (ES)
Title: Procedimiento para el barnizado electroforetico por inmersion.
Inventor: DAVID NORBERT
IPC: C25D13/10
Filed: 2000-11-29
Granted: 2003-12-01
Abstract: Procedimiento para la producción de una capa de revestimiento por barnizado electroforético por inmersión, con una mejor adherencia de las capas siguientes, por deposición catódica de una capa de revestimiento de un agente de revestimiento aplicado por barnizado electroforético por inmersión sobre un substrato conductor de la electricidad y calcinación, caracterizado porque al agente de revestimiento aplicado por barnizado electroforético por inmersión depositable catódicamente se añaden uno o varios nitritos y/o nitratos orgánicos insolubles en agua y el calcinado tiene lugar en una estufa de ventilación forzada calentada indirectamente, donde el porcentaje de aire fresco introducido en el aire circulante de la estufa es desde 0 hasta 20% en volumen del aire de la estufa.
Patent ES-2432544-T3 (ES)
Title: Copolímeros preparados usando tanto técnicas de polimerización aniónica como catalizadores de coordinación
Inventor: OZAWA YOICHI
IPC: B60C1/00
Filed: 2000-12-29
Granted: 2013-12-04
Abstract: Un procedimiento para formar un copolímero que comprende las etapas de: (i) preparar un segmento de polímero vivo usando técnicas de polimerización aniónica; (ii) modificar el polímero vivo haciéndolo reaccionar con un haluro de alquilmetal para formar un intermediopolimérico organometálico; y (iii) preparar un segundo segmento de polímero del intermedio polimérico organometálico combinando el intermedio,monómero de dieno conjugado, y un sistema catalizador de coordinación que polimerizará el monómero de dienoconjugado; en el que el sistema catalizador de coordinación se forma combinando un compuesto de lantánido, unagente de alquilación, y una fuente de halógeno.
Patent ES-2287055-T3 (ES)
Inventor: SANJURJO ANGEL
IPC: C09K11/08
Filed: 1998-12-04
Granted: 2007-12-16
Abstract: This invention relates to a method for producing activated, substantially monodisperse, phosphorescent particles and particles formed thereby. The method suspends substantially monodisperse, phosphor-precursor particles in a fluidizing gas and then introduces a reactive gas to contact the suspended phosphor-precursor particles. Heating the suspended phosphor-precursor particles to a reaction temperature then forms unactivated phosphorescent particles. In another embodiment, the phosphor-precursor particles may be heated to a reaction temperature where they decompose to form the unactivated phosphor particles. The unactivated phosphorescent particles suspended within the fluidizing gas are activated by heating the unactivated phosphorescent particles to an activation temperature forming activated, substantially monodisperse, phosphorescent particles.
Patent ES-2228775-T3 (ES)
Inventor: CARRILLO JEAN-JACQUES
IPC: G06F17/50
Filed: 2001-11-15
Granted: 2005-04-16
Abstract: The process is intended to optimize the operation of a digital protection system for protecting sets of busbars in the power station and uses a basic schematic of the electrical configuration of the power station obtained from information on the type of components used in the power station, and on the possible connections and accesses to said components. The information is assigned to management units of the digital protection system, said management units comprising peripheral measurement units and at least one centralization unit. A topological compilation process is implemented to provide a compiled schematic topology, and to provide a compiled assignment topology of the components in the power station and of their connections to the management units. A partial graph, whose structure depends on the type of information searched for and the status of each component of the power station, is obtained for each peripheral unit. A complete graph is then computed in one or more centralization units by algorithms which superpose partial graphs.
Patent ES-2230256-T3 (ES)
Title: Conjunto de acerrojamiento de una placa de obturacion que da acceso a una camara subterranea.
Inventor: ROYER JEAN-CLAUDE
IPC: E05B35/00
Filed: 2001-12-03
Granted: 2005-05-01
Abstract: Conjunto (10) de acerrojamiento de una placa (12) de obturación de una cámara subterránea, del tipo que comprende una cerradura (14) y una llave rotativa (16), delimitando dicha cerradura un orificio (26) para la introducción de la llave (16), estando dicho orificio (26) prolongado por un conducto (24) para el paso de la llave (16) que desemboca en un extremo de salida (28), comprendiendo la cerradura (14) un órgano (74) que es móvil bajo el comando de un paletón (36) de la llave (16), entre una posición de acerrojamiento y una posición de desacerrojamiento de la cerradura, estando el órgano móvil (74) provisto con un perfil (76) adecuado para ser acoplado con el paletón (36) de la llave (16) según una dirección de acoplamiento; dicho perfil (76) está dispuesto fuera del conducto de paso (24) y orientado en dirección opuesta a la del orificio (26) para la introducción de la llave, caracterizado porque la cerradura (14) comprende una pared (72) que recubre la parte esencial del órgano móvil(74), dicha pared (72) se extiende transversalmente con respecto a la dirección de acoplamiento y delimita el extremo de salida (28) de la llave, como también una abertura (102) para el paso del paletón (36) hacia el órgano móvil(74) únicamente en una posición angular predeterminada de la llave (16).
Patent ES-2250336-T3 (ES)
Inventor: LANGE ROBERT
IPC: A61B90/00
Filed: 2001-04-24
Granted: 2006-04-16
Abstract: The instrumentation comprises a spinal stabilizing longitudinal element (1). <??>A connector (6) has an opening (7) therethrough which has dimensions greater than a cross-section dimension of a machine thread section (4) of said bone-anchoring element (2). <??>A mechanism (10) is adapted to affix said bone-anchoring element (2) in said opening (7). said mechanism (10) comprising a pressure element (10) received by said bone-anchoring element (2); <??>The connector (6) has a hook portion (11) adapted to cooperate with a support (32) of the bone-anchoring element (2) for clamping the longitudinal element (1). <??>The hook portion (11) has at its bottom side a recess (12) for receiving the longitudinal element (1). The longitudinal element (1) is clamped against said support (32), the force of the support (32) on the longitudinal element (1) being approximately parallel to the axis (D) of the bone-anchoring element (2), because the support has an upper surface (42) which is perpendicular to the axis of the bone-anchoring element (2). <IMAGE>
Patent ES-2234814-T3 (ES)
Inventor: HEIFETZ RAPHAEL
IPC: E04B1/78
Filed: 2001-02-09
Granted: 2005-07-01
Abstract: A flexible reflective insulating structure includes a layer of flexible fiber-based material, and a flexible metallic layer having a first surface of emissivity less than 0.1. The metallic layer is attached to the layer of fiber-based material with its first surface facing towards the layer of fiber-based material. The fiber-based material is preferably attached to the metallic layer in a manner such that the emissivity of at least about 85% of the first surface, and preferably at least about 95% and most preferably at least about 97% is substantially unaffected.
Patent ES-2281415-T3 (ES)
Inventor: BERGENDORFF HANS
IPC: H04M3/42
Filed: 2001-04-12
Granted: 2007-10-01
Abstract: A system for routing and answering of calls from a sender (1) over a communication network (2), which system includes a receiving unit (3), arranged to detect said sender's position, and a control unit (4), connected to the receiving unit. Said control unit is connected to an event database (8) on which event data for earlier reported events are stored, containing event position information. Detected sender position is compared with the stored event position, and if they correspond with preset accuracy, the call is routed via a switching unit (9) to a call answering unit (5) for answering of the call with a message containing information about said stored event. If, on the other hand, it is judged that the sender position does not correspond with the event position, the call is routed, via the switching unit, to an operator (10) for reporting of new observed event.
Patent ES-2305076-T3 (ES)
Inventor: AUGTHUN MICHAEL
IPC: A61F2/00
Filed: 2001-04-05
Granted: 2008-11-01
Abstract: A post-shaped element for determining the spatial position of an implant (10), or the opening cross-section of an artificial indentation located in a tooth or in the stroma of a human or animal body, relative to the tissue structures surrounding it, can be introduced with a receiving section (26A) into an adapted receiving recess (10) in the implant (1) or in the artificial indentation, be affixed therein to be torsion resistant and able to again be removed there-from. In a connecting position the post-shaped element protrudes with a cantilever section (26K) beyond the opening cross-section of the receiving recess (10) or artificial indentation. To be able to easily remove the post-shaped element embedded in the impression mass, even in the case of a slanted position of the implant (1) or the longitudinal axis of the artificial indentation in relation to the surrounding tissue structures, it is suggested to ensure that the post-shaped element consists of a bottom portion (24), which can be torsion-resistantly fixated in the receiving recess (10) or the artificial indentation, and a top portion (25), which can be inserted torsion-resistantly in the bottom portion (24) or placed on said portion, wherein the top portion (25), proceeding from the connecting position of the post-shaped element, can be removed in a linear fashion from the bottom portion (24) in various directions.
Patent ES-2231513-T3 (ES)
Title: N-hidroxiformamidas sustituidas con biciclil- o heterobiciclilsulfonilamino.
Inventor: BEST DESMOND JOHN
IPC: C07D277/62
Filed: 2001-05-21
Granted: 2005-05-16
Abstract: Un compuesto de fórmula (I): en la que R se selecciona entre fenilo opcionalmente sustituido con hasta tres grupos seleccionados de forma independiente entre halógeno, alcoxi(C1-6), di-N-alquil(C1- 6)aminosulfonilo, acil(C1-6)amino, arilalcoxi(C1- 6)carbonilamino, amino, alcoxi(C1-6)carbonilo, carboxi, hidroxi y alquilo(C1-6) o dos grupos que forman juntos un anillo condensado; benzotiofeno, tiofeno opcionalmente sustituido con alquilo(C1-6), carboxi o alcoxi(C1- 6)carbonilo; furanilo; pirazol opcionalmente sustituido con hasta dos grupos alquilo(C1-6); alquilo(C1-6) opcionalmente sustituido con alcoxi(C1-6), arilalcoxi(C1- 6) o fenilo; isoxazol opcionalmente sustituido con alquilo(C1-6); benzodioxano; benzodioxepina; y benzoxazina; y R1 es biciclilo o heterobiciclilo, en el que biciclilo o heterobiciclilo significa anillos bicíclicos condensados que contienen de 4-7 átomos de anillo en cada anillo y en el que los anillos heterobiciclilo contienen hasta 4 heteroátomos en cada anillo seleccionados entre oxígeno, nitrógeno y azufre.
Patent ES-2210180-T3 (ES)
Inventor: POLEGATO MORETTI MARIO
IPC: A41D3/02
Filed: 2001-01-15
Granted: 2004-07-01
Abstract: An item of clothing, such as a coat, jacket, overcoat or the like, comprising:spacer elements which are arranged at least in an internal part of the shoulders of the item of clothing so as to generate an interspace between the shoulders of the user and the fabric which the item of clothing is made of;elements for venting warm air, produced by the user's body, that has risen in the interspace.
Patent ES-2228945-T3 (ES)
Title: Dispositivo para la eliminacion exenta de cicatrices de tatuajes.
Inventor: MALODOBRY WOLFGANG
IPC: A61M35/00
Filed: 2001-09-11
Granted: 2005-04-16
Abstract: Dispositivo para la eliminación, exenta de cicatrices, de tatuajes de la piel humana o animal que abarca una pistola para tatuar y una o varias agujas con superficie áspera de la aguja o agujas, las cuales vibran con una frecuencia de punción constante, introduciéndose las agujas de forma esencialmente vertical a la superficie de la piel, a través de ésta, en los aglomerados de pigmentos de pintura inorgánicos y/u orgánicos, destruyendo por ello mecánicamente los aglomerados y, además, un dispositivo para la introducción de sustancias irritantes de la piel en la superficie de la piel y/o en los aglomerados.