baber/WOPTO huggingface dataset:
Patent CA-2139109-C (CA)
Title: Purinone antianginal agents
Inventor: TERRETT NICHOLAS KENNETH
IPC: A61P9/00
Filed: 1993-06-18
Granted: 1997-03-25
Abstract: Compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein R1 is C1-C4 alkyl; R is C2-C4 alkyl; R3 is H or SO2NR4R5; R4 and R5 together with the nitrogen atom to which they are attached form a pyrrolidino, piperidino, morpholino or 4-N-(R6)-1-piperazinyl group; and R6 is H or C1-C3 alkyl; are selective cGMP PDE inhibitors useful in the treatment of, inter alia, cardiovascular disorders such as angina, hypertension, heart failure and atherosclerosis.
Patent CA-2139296-C (CA)
Inventor: STERNQUIST ALAN R
IPC: E06B9/44
Filed: 1994-12-29
Granted: 2005-12-13
Abstract: The present invention provides a roller shade with a variable load brake and, in a modification thereof with a lift assist. The load brake includes a compressible spring surrounding a threaded rod, the spring acting against a traveling nut mounted on the rod. The compressive friction of the traveling nut against the threads of the threaded rod continually varies during raising and lowering of the shade to provide the variable load braking capability. The lift assist uses at least one torsion spring, also associated with a shaft and coupled between a nonrotating flange and a nipple rotationally anchored to the shaft. The torsion spring system is increasingly loaded when the shade is lowered.
Patent CA-2143060-C (CA)
Inventor: TAKI OSAMU
IPC: E02D5/36
Filed: 1995-02-21
Granted: 2006-04-25
Abstract: A soil mixing apparatus that requires less drilling force comprises a shaft, a plurality of cutting blades, an excavation blade, an auger bit, a shear blade having an extendible finger. The cutting blades, excavation blade and auger bit are attached to rotate with the shaft. The shear blade is attached at a fixed longitudinal position along the shaft. The shear blade provides a variable length by attaching different length fingers that are adjustable to the soil conditions in which the mixing apparatus is used. The shear blade is also mounted to the shaft at an angle such that the shear blade rotates in the same direction as the excavation blade and the cutting blades, but at a much slower rotation rate.
Patent CA-2147643-C (CA)
Title: Selectively actuatable lighter
Inventor: MCDONOUGH JAMES M
IPC: F23Q2/16
Filed: 1993-10-22
Granted: 2002-01-08
Abstract: A selectively actuatable lighter device (10) is disclosed which includes a body defining reservoir (12) for containing a com-bustible gaseous medium such as butane, and having a valve (20) arranged to be selectively actuated between a normally closed position and an open position which permits the exit of the gaseous medium.  Such lighter (10) can selectively produce sparks at a location (19, 22) proximate to the gaseous medium exit to ignite the gaseous medium. Such lighter device (10) embodies a resi-liently releasable valve actuator (14) which normally prevents actuation of the valve (22). The valve actuator (14) includes an inter-fering portion (14A) which is selectively movable to a position out of interference with an interfering portion (12B) of the lighter body, so that the gaseous medium may be released and ignited by the sparks.  Once the valve actuator (14) is depressed and re-leased, it returns to its closed or latched position to prevent actuation of the valve to the open position. To "re-use" the lighter, the valve actuator (14) must again be moved to an unlatched position so that the valve (22) can be actuated for subsequent ignition of the gaseous medium.
Patent CA-2150607-C (CA)
Inventor: PRIMDAHL IVAR IVARSEN
IPC: B05B1/02
Filed: 1995-05-31
Granted: 2000-03-28
Abstract: A gas injector nozzle is provided herein which includes a discharge chamber with a cylindrical inner wall with a circular gas discharge orifice at its outlet end. An outer wall concentrically surrounds the inner wall, the outer wall following the chamber outlet end and being joint sharp-edged with the inner wall at the discharge orifice. The curved path has a radius of curvature R complying with the relationship: (see formula I) where l   is the length of the continuously curved path measured along the longitudinal axis of the nozzle; t is the maximal horizontal distance between the inner and outer wall; and .alpha.  is the tip angle between a line drawn tangent to the outer wall at the discharge orifice and the longitudinal axis of the nozzle.
Patent CA-2152898-C (CA)
Inventor: VRANG ASTRID
IPC: A23L29/00
Filed: 1994-01-03
Granted: 2003-04-29
Abstract: A method of isolating a lactic acid bacterial DNA fragment comprising a promotor is provided. The method involves introduction of a DNA molecule, containing a transposable element comprising a promotorless structural gene as a promotor probe gene, into a population of a lactic acid bacterium. The invention pertains to construction of a recombinant lactic acid bacterium comprising a regulatable promotor by using the above method. A recombinant lactic acid bacterium comprising a gene coding for a desired gene product and operably linked thereto a regulatable lactic acid bacterial promotor not natively associated with the gene are further provided. The invention as described relates to the use of such a recombinant lactic acid bacterium and DNA constructions comprising a regulatable lactic acid bacterial promotor.
Patent CA-2157248-C (CA)
Title: Crystalline form of dihydro-2, 3 benzodiazepine derivative
Inventor: ANDERSON BENJAMIN ALAN
IPC: A61P25/18
Filed: 1995-08-30
Granted: 2000-02-22
Abstract: A physical form of having an X-ray powder diffraction pattern with d spacings at 12.78, 9.48, 8.99, 8.4, 8.23, 6.39, .27, 5.73, 4.01 and 3.96 .ANG.. The compound is useful as an AMPA antagonist.
Patent CA-2158744-C (CA)
Inventor: LARKIN MARK E
IPC: A61M39/10
Filed: 1994-03-22
Granted: 2006-04-25
Abstract: A securing collar (10) is used in combination with two tubular flow connectors (12, 14) to prevent the inadvertent disconnection of I.V. tubing sets. The securing collar (10) includes a housing (26) supported by one of the connectors, a radial flange (42) extending from the housing (26), a tubular collar (44) having an outwardly splayed end, at least two notches (52) that separate the splayed collar (44) into at least two elongated segments, a transition portion (54) on the exterior of the collar, and a sliding annular locking ring (60). The locking ring (60) slides on the collar (44) from the proximal end over the transition portion to the distal segments so that the annular locking ring (60) forces the splayed and segmented distal portions radially inward to grip the second connector.
Patent CA-2160910-C (CA)
Title: Implant for an osteosynthesis device, especially of the backbone
Inventor: HENRY PATRICK
IPC: A61B17/58
Filed: 1994-04-18
Granted: 2003-12-16
Abstract: PCT No. PCT/FR94/00435 Sec. 371 Date Oct. 19, 1995 Sec. 102(e) Date Oct. 19, 1995 PCT Filed Apr. 18, 1994 PCT Pub. No. WO94/23660 PCT Pub. Date Oct. 27, 1994An implant for an ostheosynthesis device, in particular for the spine, comprises an anchoring portion (11) for anchoring to bone and a body in which a channel (13) is formed suitable for receiving a rod (T), the channel opening out sideways in the body, a hollow element (20) suitable for surrounding the body (12) and possessing two notches suitable for receiving the rod on either side of the body (12), and a screw (30) for fixing the hollow element on the body. According to the invention: the hollow element is a cover (20) fitting over the body with a rounded top portion (21b) in which an opening (25) is formed, the body (12) includes a tapped hole (14) facing said opening, and the head (31) of a screw (30) bears against the top (21b, 25a) of the cover, its threaded portion (32) being screwed in the tapped hole through said opening.
Patent CA-2162047-C (CA)
Title: Attachment means for a belt
Inventor: RONNBERG PETER
IPC: A61F13/62
Filed: 1994-05-06
Granted: 2008-02-05
Abstract: The invention relates to a belt (1) for flexible material for use with absorbent garments, wherein the belt comprises attachment means (6, 9, 10, 11, 21, 22) securely attached at one end. The attachment means is in the form of a flexible strip of hook elements such as used for releasable hook and loop type connectors and is used for securing that one end to an outer surface of the belt. In order to provide greater comfort for the wearer the attachment means itself is located approximately centrally and extends with its greatest dimension (a) in the width direction of the belt where dimension (a) is between 25 % to 75 % of the belt width (z).
Patent CA-2163534-C (CA)
Title: Inhibition of hair growth
Inventor: AHLUWALIA GURPREET S
IPC: A61K31/047
Filed: 1994-05-16
Granted: 1998-12-15
Abstract: Mammalian hair growth is reduced by applying to the skin a composition including an inhibitor of 5-lipoxygenase.
Patent CA-2166685-C (CA)
Title: An enzyme with protease activity
Inventor: DALBOGE HENRIK
IPC: A23K20/189
Filed: 1994-07-05
Granted: 2007-07-03
Abstract: A DNA construct comprising a DNA sequence encoding an enzyme exhibiting protease activity, which DNA sequence comprises the DNA sequence shown in SEQ ID No. 1 or 2 or an analogue of any of these sequences being at least 80 % homologous to the DNA sequence shown in SEQ ID No. 1 or 2. The proteases encoded by the DNA  sequences have an acid pH optimum.
Patent CA-2166901-C (CA)
Inventor: BOIGEGRAIN ROBERT
IPC: C07D231/54
Filed: 1991-08-20
Granted: 1999-01-26
Abstract: The present invention relates to new pyrazole derivatives possessing an amide group substituted with an amino acid or one of its derivatives at position 3 and variously substituted in positions 1, 2, 4 or 5 of the pyrazole ring, to a process for preparing these and to pharmaceutical compositions containing the said pyrazole derivatives as an active ingredient.  The novel compounds are capable of binding to neurotensin receptor and are capable of being useful in pathological states associated with dysfunction of the dopaminergic systems.  The 3-amidopyrazole have formula (I):                      (see fig. I) in which: X and X', together with the carbon atom to which they are linked, form a cycle of formula b:     (see fig. II) in which W is a carbon atom, n4 is 2, 3 or 4, and n5 is 2 or 3; the cycle of formula b is attached to >N-R and to C(O)-Z through one carbon atom of one or other of the two rings; and the cycle b is optionally substituted on one and/or the other of the rings with one or two C1-C4 alkyl groups; RI represents:     a phenyl group substituted by R a, R' a and R" a, wherein R a, R' a and R" a each independently represent a hydrogen atom, a halogen atom, a hydroxyl, a linear or branched C1-C4 alkyl group, a C1-C4 alkoxy group, a trifluoromethyl group,   a trifluoromethoxy group, a nitro group, a carboxyl group or an amino group;      a tetrahydronaphthyl group; a naphthyl group substituted with R a, R' a and R" a as defined above; or a quinolyl or isoquinolyl group optionally substituted with R a, R' a and R" a as defined above; R represents hydrogen or linear or branched C1-C4 alkyl; n represents 0, 1, 2 or 3; Z represents a hydroxyl group; a C1-C6 alkoxy group; an oxygen atom substituted with a carboxylic acid-protecting group, wherein the carboxylic acid-protecting group is selected from the group consisting of tert-butyl, benzyl, benzyl substituted with a halogen atom, C1-C6 alkyl, trifluoromethyl, trifluoromethoxy or carboxyl;    an amino group; or a nitrogen atom substituted with a carboxyalkyl in which the alkyl is a linear or branched C1-C6 alkyl; R IV represents a hydrogen atom, a halogen atom or a C1-C6 alkyl; R V represents:    a phenyl group substituted by R5, R' 5 and R" 5, where R5, R' 5 and R" 5 each independently represent a hydrogen atom, a halogen atom, a linear or branched C1-C4 alkyl, a hydroxyl, a C1-C4 alkoxy, a nitro, a trifluoromethyl, a trifluoromethoxy, a cyano, an amino, a carboxyl, a C1-C4 carboxyalkyl or a phenyl;    a naphthyl group unsubstituted or substituted with a C1-C4 alkyl;    a pyridyl group; a styryl group unsubstituted or substituted with a C1-C4 alkyl;     or alternatively R IV and R V considered together represent:    a group   in which the phenyl group substitutes the pyrazole at position 5 and the group -(CH2)i - in which i = 1 to 3 substitutes the pyrazole at position 4; W1, W2 and W3 substitute the benzene ring and independently represent hydrogen, a halogen or a hydroxyl group; or one of its salts with organic or inorganic acids or with inorganic or organic bases.
Patent CA-2169808-C (CA)
Inventor: LESAGE ROBERT P
IPC: E21B43/24
Filed: 1996-02-19
Granted: 2001-04-17
Abstract: Disclosed is a method for recovering highly viscous oil from a formation penetrated by a single horizontal wellbore using steam stimulation.  A wellbore is drilled into the formation comprising a substantially vertical section and a substantially horizontal section.  The vertical section of the wellbore is completed with a casing and a production tubing that extends from the surface to the beginning of the horizontal wellbore.  The horizontal section of the wellbore is completed with a slotted lined and the entire wellbore is completed with an injection tubing that extends from the surface to the far end of the horizontal wellbore.  After the wellbore is completed, steam is circulated in and out the horizontal wellbore at a pressure below the formation's fracture pressure to heat the formation surrounding the horizontal wellbore by transient conduction and steam-lift fluids from the horizontal wellbore.  Circulation of the steam is continued until the temperature of the horizontal wellbore reaches the saturation temperature of steam at horizontal wellbore pressure.  Thereafter, a slug of steam is injected into the horizontal wellbore below fracture pressure followed by a short soak period.  The well is then flowed back until the amount of produced fluids substantially decline.  Steam circulation is resumed and steam-lifted fluids including oil are recovered until the oil recovery is unfavorable. The sequence of steam slug injection, soak period, flow back and steam circulation is repeated for a plurality of cycles until the rate of oil is then favorable.
Patent CA-2174475-C (CA)
Title: Casting equipment
Inventor: STEEN IDAR KJETIL
IPC: B22D15/00
Filed: 1996-04-18
Granted: 2006-12-12
Abstract: Casting equipment for continuous or semi-continuous water casting of metals, in particular casting of billets or ingots of aluminium, comprising a mould cavity (4) with an inlet (2) that is upwardly open, and an intermediate, inwardly facing and heat insulated overhang or hot-top (8), and an outlet comprising a vertically movable supporting device (5), together with means (10) for the supply of water to cool the melted metal. The wall in the mould cavity is wholly or partly constituted by a permeable material, whereby oil and/or gas are supplied through the permeable material to form an oil- and/or gas layer between the metal and the wall of the mould preventing the metal to come into direct contact with the wall of the mould. The oil and the gas are supplied separately through two independent, and by means of a sealing element (14) or the like, physically separated rings or wall elements (12, 13), whereby the upper wall element (12) for the supply of oil is arranged above the area where the freezing front of the metal is located, while the lower wall element for the supply of gas is arranged directly vis-a-vis to the freezing front (19) of the metal (11) and extends from the lower part of the mould cavity and beyond the contact point between the metal and the mould wall.
Patent CA-2181568-C (CA)
Inventor: WOLF STANLEY F
IPC: A61K38/20
Filed: 1995-01-20
Granted: 2007-09-18
Abstract: Cette invention se rapporte à l'utilisation de l'interleukine-12 pour prévenir, atténuer et traiter la réaction du greffon contre l'hôte chez un mammifère nécessitant un tel traitement.
Patent CA-2182725-C (CA)
Title: Method of cleaning and disinfecting contact lens, and apparatus therefor
Inventor: CHANG CHING-TSAI
IPC: A61L12/04
Filed: 1996-08-05
Granted: 2005-03-15
Abstract: A method of cleaning and disinfecting contact lenses, including the steps of a) transmitting a ultrasonic energy field toward a pair of contact lenses being suspended in a solution medium in a cleaning cup, causing a cavitation to be produced to remove dirt from the contact lenses; b) keeping the solution medium to be maintained standing still in for about 3-5 minutes for permitting suspended substance to settle to the bottom of the solution medium; c) using heating means to heat the solution medium to about 90°C for about 15-20 minutes so as to disinfect bacteria and degrade toxic substance carried on the contact lenses; and d) gradually cooling down the temperature of the solution medium to room temperature. The invention relates also to the apparatus for the performance of the method which includes a ultrasonic wave guide and a control circuit board mounted in a housing, a serving container unit mounted in the ultrasonic wave guide to hold a lens holder in NaCl, permitting contact lenses to be cleaned by ultrasonic waves from a ultrasonic speaker and disinfected by heat from a heating rod.
Patent CA-2185547-C (CA)
Inventor: NAIENI SHAHROKH A
IPC: D04H1/42
Filed: 1995-03-10
Granted: 2001-01-30
Abstract: In preparing individualized polycarboxylic acid crosslinked fibers, defibration requirements are reduced to obtain a particular wet responsiveness and satisfactory absorbency properties are maintained even without washing or bleaching and washing, and improved dry resiliency is obtained, by using a reduced surface tension solution of polycarboxylic acid crosslinking agent.
Patent CA-2196478-C (CA)
Title: Membrane composition and method of preparation
Inventor: MATSUURA TAKESHI
IPC: B01D71/68
Filed: 1997-01-31
Granted: 2003-01-28
Abstract: The present invention relates to membranes useful in the separation of water from a solution containing volatile organic compounds and water. The membranes may be used in dehydrating an organic/water mixture to purify an organic when an organic is of interest or, alternatively, producing pure water from an organic/water mixture when clean water is of interest. The membranes include a hydrophilic base polymer, an optional pore-forming polymer and a surface modifying macromolecule (SMM) which imparts surface hydrophobicity to the membrane.
Patent CA-2202142-C (CA)
Inventor: CALLAHAN RICHARD A
IPC: B01D53/22
Filed: 1995-10-10
Granted: 2006-03-07
Abstract: A membrane process and apparatus are described for the production of a desir ed very high purity permeate gas by use of a multiple stage membrane process wherein in a primary stage a process feed gas mixture is provided to a primary membrane separator unit comprising a membrane having a relatively high intrinsic permeability to provide an intermediate permeate gas and a retentate gas, and providing the intermediate permeate gas in a secondary stage to a secondary membrane separator unit comprising a membrane having a relatively low intrinsic permeability, to produce therefrom a very high purity permeate gas product.
Patent CA-2210337-C (CA)
Title: Procede de separation de racemates de nitriles de 2-aryl-2-alkyl-.omega.-alkylaminoalcanes
Inventor: SEITZ WERNER
IPC: C07C253/34
Filed: 1996-01-20
Granted: 2004-04-27
Abstract: Un procédé permet de séparer les racémates d'acétonitriles de phényle ayant la formule (I), dans laquelle R<1>, R<2>, R<3> et n ont la notation donnée dans la description. Selon ce procédé, on dissout les racémates (I) dans un solvant polaire, on y ajoute 0,5 à 1,0 mole d'acide camphosulfonique optiquement actif par mole de composé (I), on chauffe le mélange jusqu'à une température comprise entre 40 et 100  DEG C, on le laisse refroidir et on extrait l'acétonitrile de phényle (I) optiquement actif du sel ainsi obtenu.
Patent CA-2212893-C (CA)
Title: Prokinetic oxadiazoles
Inventor: BOSMANS JEAN-PAUL RENE MARIE A
IPC: A61P1/00
Filed: 1996-02-21
Granted: 2007-01-16
Abstract: The present invention concerns novel oxadiazole derivatives of formula (I), the N-oxide forms, the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein R1 is hydrogen or halo; R2 is C1-6alkyl, C2-6alkenyl or C2-6alkynyl; R3 is hydrogen; or R2 and R3 taken together may form a C2-3alkanediyl radical wherein one or two hydrogen atoms may be replaced by C1-4alkyl; R4 is hydrogen or C1-6alkyloxy; X is a bivalent radical of formula (a-1), or (a-2), L is a radical of formula -Alk-R5 or -Alk-O-R6, Alk is C1-12alkanediyl; R5 is hydrogen, cyano, C1-6alkylcarbonyl, C1-6alkylsulfinyl, C1-6alkylsulfonyl, aryl, arylcarbonyl, tetrahydrofuran, dioxolane, dioxolane substituted with C1-6alkyl, dioxane, dioxane substituted with C1-4alkyl; R6 is hydrogen, aryl, C1-6alkyl, hydroxyC1-6alkyl, C1-6alkylcarbonyl; aryl is defined as phenyl or phenyl substituted with up to three substituents select ed from halo, C1-6alkyl or C1-6alkyloxy. It further relates to pharmaceutical compositions comprising them, processes for preparing said compounds and compositions, and the use thereof as a medicine, in particular in the conditions involving a decreased motility of the colon.
Patent CA-2217610-C (CA)
Title: Pet chew with edible tubular wrapper and method for making same
Inventor: MOHILEF DAVID MICHAEL
IPC: A01K15/02
Filed: 1997-10-08
Granted: 2006-01-31
Abstract: The present invention provides a new pet chew comprised of an inner bone or bone-like core, and at least one outer edible tubular wrapper layer composed of dried animal viscera or other tubular food product compositions.
Patent CA-2217970-C (CA)
Title: Waterborne polymers having pendant allyl groups
Inventor: TAYLOR JAMES WAYNE
IPC: C09D4/00
Filed: 1996-04-12
Granted: 2003-06-03
Abstract: This invention provides polymers useful in coating compositions. The polymer s are prepared via a free radical polymerization using ethylenically unsaturat ed monomers. The polymers of this invention possess pendant allylic groups whic h are capable of effecting free-radical flux when the compositions are applied  to a substrate and exposed to oxygen. Coatings formed from preferred compositions possess superior solvent, print, and block resistance.
Patent CA-2225803-C (CA)
Inventor: KAPLUNENKO VSEVOLOD
IPC: H03K19/195
Filed: 1996-06-20
Granted: 2001-10-23
Abstract: The present invention relates to a logic circuit arrangement comprising sign al input means and signal output means (1, 2) (respectively) and a number of SF Q circuits comprising Josephson junctions wherein carrier means are used for carrying digital information. SFQ circuits comprising Josephson junctions ar e sampled at the input/output for producing DC voltages and a train comprising  at least two single flux quanta is used as carrier means for information and  phase locking between at least two Josephson junctions is used to provide at  least two different dynamic states of which at least one provides an output signal.
Patent CA-2245216-C (CA)
Title: Disposable food contact compatible microwaveable containers including mica and talc having at least one micronodular surface and process for their manufacture
Inventor: ROGERS RICHARD J
IPC: C08J5/18
Filed: 1998-08-17
Granted: 2007-04-24
Abstract: Disposable food contact compatible microwaveable containers having at least one micronodular surface are disclosed. These containers including plates, bowls, cups, trays, buckets, soufflé dishes, and lids are prepared from polypropylene or propylene-ethylene copolymer or blends, talc and mica mixtures and pigment and are thermoformed into the shape of the aforementioned articles of manufacture exhibiting (a) a micronodular surface on at least one side; (b) a melting point of not less than about 250°F;  said articles of manufacture being dimensionally stable and resistant to grease, sugar, and water at temperatures up to at least 250°F and being of sufficient toughness to resist cutting by serrated polystyrene flatware.