baber/WOPTO huggingface dataset:
Patent DE-69320367-T2 (DE)
Inventor: FERRARI LORENZO
IPC: C07K5/078
Filed: 1993-11-30
Granted: 1998-12-17
Abstract: PCT No. PCT/EP93/03354 Sec. 371 Date May 24, 1995 Sec. 102(e) Date May 24, 1995 PCT Filed May 24, 1995 PCT Pub. No. WO94/12527 PCT Pub. Date Jun. 9, 1994The present invention is referred to sulphur-acylated derivatives of L-pyroglutamyl-L-cysteine of formula (I)    <IMAGE>  (I)  where R is a linear or branched alkyl containing 1 to 6 carbon atoms, their pharmaceutically acceptable salts, the process for their preparation, and the pharmaceutical compositions containing same. Said derivatives are suitable for the treatment of diseases connected with glutathione deficiency.
Patent DE-69322382-T2 (DE)
Inventor: HEYN LAWRENCE
IPC: A61F2/06
Filed: 1993-02-23
Granted: 1999-04-29
Abstract: An apparatus for deploying a radially self-expanding stent includes proximal and distal sleeves respectively containing proximal and distal end portions of the stent in a reduced radius delivery configuration. The sleeves can abut one another and thus contain the entire length of the stent, or may be used in combination with an outer catheter surrounding the sleeves and containing the medial region of the stent. In either event, once the stent and sleeves are positioned at the intended fixation site, the sleeves are moved axially with respect to one another to permit radial self-expansion of the stent only over its medial region, while the sleeves continue to contain the axially outward regions of the stent. Eventually, upon sufficient movement of the sleeves axially relative to one another, the stent becomes totally free of the sleeves, resulting in radial expansion over the entire stent length. The axial relative movement of the sleeves can be controlled by two or more catheters mounted movably with respect to one another, one catheter integral with each of the sleeves. Alternative arrangements for separating the sleeves include an externally threaded inner catheter, and a dilatation balloon or membrane expandable to force the sleeves apart from one another.
Patent DE-69325909-T2 (DE)
Inventor: GIANNELLA GIANNI
IPC: A61C1/08
Filed: 1993-06-02
Granted: 2000-01-20
Abstract: PCT No. PCT/EP93/01388 Sec. 371 Date Jan. 12, 1995 Sec. 102(e) Date Jan. 12, 1995 PCT Filed Jun. 2, 1993 PCT Pub. No. WO93/24069 PCT Pub. Date Dec. 9, 1993A support device for a dentist's drill comprising a support, an articulated arm comprising two articulated quadrilateral devices disposed in series with one another, and an adjustment device operable to vary the direction of the working axis of the drill. The support is provided with a fixing device for connecting it to a seat back of a dentist's chair and the articulated arm can assume a working condition in which the two articulated quadrilateral devices are disposed at 90 DEG  to one another.
Patent DE-69328991-T2 (DE)
Inventor: GREGORY JAMES L
IPC: B65D41/04
Filed: 1993-04-23
Granted: 2000-11-16
Abstract: A plastic linerless sealing closure comprises   a plastic closure (14) having a base wall (15) and a peripheral skirt (16) with threads (17) on the skirt adapted to engage the threaded finish of a container, the closure including an annular flexible flange (20) that extends downwardly from the underside of the base wall (15) and radially inwardly of the closure, the annular flexible flange (20) having a smooth continuous frusto-conical surface (21) which in use faces the finish and a free edge (24), the width and position of the flange (20) being such that the free edge (24) thereof normally extends beyond the inner edge (22) of the finish and the sealing engagement being normally intermediate the free edge (24) of the flange and the base wall (15), the flange being capable of flexing intermediate the free edge and the portion adjacent the base wall such that the free edge may move toward the base wall and such that the flange is capable of flexing differentially about the periphery of the flange.   The closure may be used on plastics containers, the differentially flexible flange compensating for sealing imperfections in the container finishes. <IMAGE>
Patent DE-69401354-T2 (DE)
Inventor: FAYOLLE JEAN
IPC: C09J7/10
Filed: 1994-04-20
Granted: 1997-09-18
Abstract: Continuous anti-adherent treatment process for a surface-tacking thermofusible adhesive, characterized in that a carrier belt (1) is continuously displaced in translation, the upper surface thereof being cooled by its lower face, said surface being covered by a layer (3) of an anti-adherent protection product, the thermofusible adhesive (4) to be treated being deposited on the protection product layer. The assembly (7) comprising of the adhesive (4) and the layer (3) of protection product is folded back on itself so as to release a composite material (8) consisting of a double thickness (4, 4') of thermofusible adhesive sandwiched between two layers (9, 9') of anti-adherent protection product (3) and the composite material is cut into fragments.
Patent DE-69406352-T2 (DE)
Inventor: HOTCHKISS ROBERT N
IPC: A61F5/01
Filed: 1994-03-17
Granted: 1998-05-07
Abstract: A device for treating and preventing injuries and contractures of the elbow joint, particularly supination-pronation contractures and proximal radial head fractures. The device includes bracing sections for fixing the device to the radius and the ulna, and for permitting movement of the attached radius continually along a path which is adapted and adjusted to be aligned with the kinematic axis of the proximal radial- joint. <IMAGE>
Patent DE-69413938-T2 (DE)
Inventor: DE KEYZER NOEL RAYMOND MAURICE
IPC: C08F8/42
Filed: 1994-12-22
Granted: 1999-03-18
Abstract: A releasable pressure sensitive adhesive composition comprising:   (a) a block copolymer comprising at least one poly(monovinyl aromatic hydrocarbon) block and at least one poly(conjugated diene) block and having a vinyl content of at least 3% by weight,   (b) a tackifying resin, and   (c) a plasticizer, wherein the block copolymer has been cross-linked through its vinyl groups by means of a reaction with an organohydrogenpolysiloxane crosslinking agent containing at least two hydrogen atoms being directly bonded to a silicon atom in the presence of a crosslinking catalyst and wherein the plasticizer is present in an amount of from 1 to 50 parts by weight per 100 parts by weight of block copolymer. The releasable adhesive composition can be suitably applied in removable self-adhering memo notes and in removable tapes and labels.
Patent DE-69423545-T2 (DE)
Inventor: ISHINAGA HIROYUKI
IPC: B41J2/05
Filed: 1994-06-28
Granted: 2000-08-03
Abstract: A substrate for ink-jet print head having a plurality of elements for ejecting ink and a driving circuit for driving the plurality of elements comprises:     an interface for inputting/outputting data for printing;   detecting means for detecting a state of the substrate; processing means for processing concerning to the driving of the plurality of elements in accordance with the print data, based on detection results of said detecting means.   <IMAGE>
Patent DE-69424493-T2 (DE)
Inventor: WOODFIELD DAVID ALAN
IPC: G06F19/00
Filed: 1994-10-14
Granted: 2000-09-21
Abstract: An interactive system, comprises a local controller (8) operable to control data flow to and from at least two local handsets (11,22) for generating data. The local controller (8) includes a store (28) for storing data and a processor. A central controller (1) is connectable to the local controller, and a display (12) is provided for displaying data locally from the central controller and the local controller. The local controller (8) stores data generated by each local handset and selectively transfers stored data to the central controller (1). A handset for use in the system comprises a transmitter and a receiver (9) for transfer of data between the handset (11,22) and the local controller and input means to input data for controlling the output of the display via the local controller is input to the local controller by means of a cursor control (33) laterally movable over a plane (36) and a sensor (38,41) for sensing a position of the cursor control within the plane (36) and causing a cursor on the display (12) to take up a similar position. A method of operating the system comprises broadcasting first data from the central controller to which the local controller responds by causing the display to display the broadcast first data. Second data from each local handset relating to the first data is stored in the local controller and then selectively transferred to the central controller if predetermined conditions are satisfied. <IMAGE>
Patent DE-69531387-T2 (DE)
Inventor: BOUT ABRAHAM
IPC: C12P21/02
Filed: 1995-08-15
Granted: 2004-04-22
Abstract: The invention provides novel vectors derived from adenovirus which are specifically suitable for use in methods of gene therapy. <??>The vectors have a deletion compared to wild-type adenovirus in that the E1 region is not present in a functional manner. <??>Additionally the vectors are characterized in that they do contain a part of the E3 region of adenovirus which is biologically functional. This results in vectors which do normally not lead to expression of adenoviral proteins, but which in the cases where such proteins do become expressed will repress the host's immunological response to said proteins. Thereby host cells infected (provided) with the vector will live longer. Therefor the product introduced into said cells providing the therapy will be produced in larger amounts, or at least for a prolonged period. Preferably the vector comprises genetic information for antisense therapy, or for genes which will combat tumors, such as genes encoding cytokines, preferably IL-1, or so called suicide genes, such as Herpes Simplex Virus thymidine kinase. <??>Methods for producing said vectors and methods of gene therapy or uses therein are also disclosed.
Patent DE-69533454-T2 (DE)
Inventor: MCGUCKIN JAMES F JR
IPC: A61B17/072
Filed: 1995-12-05
Granted: 2005-09-01
Abstract: Surgical method and apparatus for resectioning tissue, preferably lumenal tissue, with a remaining portion of an organ being anastomized with staples or other fastening means, preferably endolumenally. The apparatus may be inserted via a naturally occurring body orifice or a surgical incision and then advanced using either endoscopic or radiological imaging guidance to an area where surgery is to be performed. Under endoscopic or diagnostic imaging guidance the apparatus is positioned so tissue to be resected is manipulated into an inner cavity of the apparatus. The apparatus then cuts the diseased tissue after stapling and retains the diseased tissue within the apparatus. The rent resulting in a border of healthy tissue is anastomosed with surgical staples.
Patent DE-69602400-T2 (DE)
Inventor: KOSKY JULIUS
IPC: G09F3/03
Filed: 1996-02-07
Granted: 1999-10-14
Abstract: A security device comprises a cable whose ends are engageable within a plunger. The cable is threaded around a door handle or other item to be secured and then, with the cable ends engaged therein, the plunger is slid within a housing for retention by a locking slide. Retraction of the plunger into the housing moves a slide upwardly. This movement causes a pivotally mounted striker to be flipped from one end position to another by an over-centre spring arrangement. In moving, the striker strikes a number of wheels each carrying a sequence of numbers. The wheels are rotated and a random number is displayed. If, subsequently, the plunger is released to release the cable, the wheels are struck again by the striker whereby the displayed number is changed. The number is changed again if the plunger is repositioned. The chance of the same number being randomly generated is insignificant. Thus, any opening and closing of the security device is immediately apparent because of the change in the number displayed.
Patent DE-69609993-T2 (DE)
Inventor: NICHOLSON PETER
IPC: C07D273/00
Filed: 1996-11-04
Granted: 2000-12-21
Abstract: Disclosed are "acid-amide" calixarenes of formula (I) wherein: L is [-CH2-] or [-O-CH2-O-] and may be the same or different between each aryl group; R5 is H, halogen, or C1-C10 aliphatic hydrocarbyl group, C6-C20 aryl group, C6-C20 hydrocarbyaryl group, any of which may optionally be substituted by one or more halo or oxo groups or interrupted by one or more oxo groups, and R<5> may be the same or different on each aryl group; R<1> comprises an optionally protected carboxy group; two groups out of R<2>, R<3>, and R<4> are H; the one group out of R<2>, R<3>, and R<4> not being H comprises an amide goup. The amide group may be linked to a second calixarene to form a dimer. Also disclosed are methods of use of such calixarenes for the purposes of metal sequestration, especially of lanthanides and actinides. Also disclosed are calixarene dimer derivatives of the calixarenes of the invention. Also disclosed are processes for preparing the calixarenes and dimers.
Patent DE-69613561-T2 (DE)
Inventor: WILKINSON FRANCIS
IPC: A61L24/00
Filed: 1996-01-29
Granted: 2002-04-18
Abstract: There is disclosed a method for effecting a reaction by irradiating a substance which absorbs the radiant energy until the reaction is complete and the absorbency of the material changes so as to reduce or cease absorption of further radiant energy.
Patent DE-69625801-T2 (DE)
Inventor: LATTIN A
IPC: A61N1/30
Filed: 1996-03-15
Granted: 2003-11-13
Abstract: An electrotransport delivery device (10) with a display (14) having only on and off states, and a method of operating the display (14), are provided. Preferably, the display 14 is a light (e.g., a light emitting diode) with lit and unlit states or an audible alarm (e.g., a beeper) with sounding and silent states. The device (10) counts and stores the number of events (e.g., patient initiated drug delivery or sensed patient condition) which occur over a predetermined period of time (e.g., the period of time over which the device is worn by the patient). The event count is displayed by cycling the display (14) between on and off states according to a predetermined regimen which correlates the number of on/off cycles to the number of events. The device and method permit the use of a simple and inexpensive means (e.g., an LED) to display (e.g., to a medical technician) the number of e.g., patient initiated doses delivered over a previous period of therapy.
Patent DE-69628416-T2 (DE)
Inventor: SOUTHAN GARRY J
IPC: A61P25/28
Filed: 1996-03-22
Granted: 2004-05-06
Abstract: This invention is directed to a pharmacologically acceptable composition for inhibiting nitric oxide synthase in a mammal, which includes a mercapto or seleno derivative and a pharmaceutically acceptable carrier. The invention also concerns a method of inhibiting nitric oxide synthase, selectively inhibiting the inducible isoform of nitric oxide synthase, and treating various conditions where there is an advantage in inhibiting nitric oxide biosynthesis. The method includes the step of administering to a mammal a mercapto or seleno derivative in pure form or in a pharmaceutically acceptable carrier.
Patent DE-69636984-T2 (DE)
Inventor: FREEMAN FRANK
IPC: A61F15/00
Filed: 1996-07-25
Granted: 2007-12-20
Abstract: A thin film device for medical applications such as a wound dressing including an occlusive layer having an edge portion about at least a portion of the thin film device and a non-continuous, hydrocolloid-containing polymeric support layer overlying the edge portion of the occlusive layer.
Patent DE-69706280-T2 (DE)
Inventor: LEDUC MICHEL
IPC: B42D15/10
Filed: 1997-01-17
Granted: 2002-05-08
Abstract: The electronic module (6) has a support substrate for a microcircuit (7) which is connected to an antenna (2) to allow non-contact communication between the card and an external device. The antenna is contained entirely in the electronic module, and has its winding formed in the plane of the supporting substrate. The antenna is in the shape of a circular or square spiral approximately 12 mm across, with its terminals connected to the contact pads of the microcircuit. The antenna has between six and fifty turns, each of width between 50 and 300 micron, and separated by a distance of between 50 and 200 micron.
Patent DE-69716953-T2 (DE)
Inventor: CLAUSI ROBERT N
IPC: B27N3/02
Filed: 1997-06-27
Granted: 2003-08-21
Abstract: A high density fiber product is made from plant fibers containing natural lignin. Plant fibers ranging in size below about 3000 microns in diameter are used. Binding agents and other additives may be mixed with the fibers to enhance product or process performance. The plant fibers or mixture of fibers and additives are heated to between about 50 degrees C to about 140 degrees C. The heated fibers are compressed in a mold to an average density of about 50 pounds per cubic foot to about 100 pounds per cubic foot. Compression pressures of between 500 psi and 4000 psi are used to achieve product densities within this range. The compressed fibers are cured under these temperature and pressure conditions. After the curing time has elapsed, the compressed fiber product is released from the mold and the mold may be reused. A high density product made from small plant fibers is provided.
Patent DE-69728679-T2 (DE)
Inventor: ZHU LINFANG
IPC: C09D11/10
Filed: 1997-09-24
Granted: 2005-04-21
Abstract: Disclosed are certain substituted styrenic binder resins and ink compositions comprising such binder resins. An example of the binder resin is formula (I), wherein X is OR1 wherein R1 is C1-C6 haloalkyl, C1-C6 hydroxyalkyl, C1-C6 alkylcarbonyl, C1-C6 aminoalkyl, cyano C1-C6 alkyl, or C1-C6 alkoxy C1-C6 alkyl; or X is NR2R3 wherein R2 and R3 are hydrogen, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 hydroxyalkyl, C1-C6 alkylcarbonyl, C1-C6 aminoalkyl, cyano C1-C6 alkyl, or C1-C6 alkoxy C1-C6 alkyl. Also disclosed are jet ink compositions suitable for jet printing identifying marks on substrates such as paper, glass, metal, ceramic, or plastic substrates comprising a carrier, a colorant, and a binder resin. Disclosed also are processes for printing using the inventive ink compositions.
Patent DE-69733966-T2 (DE)
Inventor: AMSELEM SHIMON
IPC: A61K9/48
Filed: 1997-04-02
Granted: 2006-05-18
Abstract: Lipophilic substances of poor oral bioavailability are mixed with at least one solid fat and phospholipid to obtain a dried solid composition suitable as an oral dosage form. The solid lipid compositions are exemplified for food additives or dietary supplements such as Coenzyme Q10 and for pharmaceuticals such as dexanabinol. The Coenzyme Q10-dry lipid mixtures shows improved drug release in vitro and enhanced oral bioavailability in vivo compared to a commercial CoQ10 formulation. The dexanabinol-dry lipid mixture similarly shows greatly enhanced oral bioavailability compared to known formulations.
Patent DE-69801987-T2 (DE)
Inventor: KONG HUA-SHUANG
IPC: H01L21/205
Filed: 1998-03-19
Granted: 2002-05-02
Abstract: A susceptor is disclosed for minimizing or eliminating thermal gradients that affect a substrate wafer during epitaxial growth. The susceptor includes a first susceptor portion including a surface for receiving a semiconductor substrate wafer thereon, and a second susceptor portion facing the substrate receiving surface and spaced from the substrate-receiving surface. The spacing is sufficiently large to permit the flow of gases therebetween for epitaxial growth on a substrate on the surface, while small enough for the second susceptor portion to heat the exposed face of a substrate to substantially the same temperature as the first susceptor portion heats the face of a substrate that is in direct contact with the substrate-receiving surface.
Patent DE-69815277-T2 (DE)
Inventor: GIORGETTI LUCA
IPC: A61P27/16
Filed: 1998-04-14
Granted: 2003-12-18
Abstract: Pharmaceutical composition containing nimesulide in a hydroalcoholic solution and a mixture of traditional vehicles and excipients for local use and application to the oral and rhinopharyngeal cavity for the treatment of inflammation of oral and rhinopharyngeal mucosae.
Patent DE-69819241-T2 (DE)
Inventor: WORKUM JAN
IPC: C05F17/02
Filed: 1998-05-20
Granted: 2004-07-22
Abstract: A composting apparatus for converting compost material in a hall is provided with a conveying system having an upwardly extending conveyor belt which, at or adjacent the bottom end thereof, comprises at least one digging wheel. This digging wheel has a wheel body which is open on one side and comprises, along the circumferential side thereof, digging elements which are open in the direction of rotation of the digging wheel. These digging elements are also of open design on the side facing the conveyor belt. Via an opening on the inside of each of the digging elements and via the open side of the wheel body of the digging wheel, the excavated compost material is laterally moved onto the conveyor belt and, by the use of this conveyor belt, discharged in order to be deposited elsewhere in the hall. <IMAGE>
Patent DE-69828533-T2 (DE)
Inventor: SHEPODD JON
IPC: C01B13/02
Filed: 1998-03-19
Granted: 2005-06-02
Abstract: A composition suitable for safely removing hydrogen from gaseous mixtures containing hydrogen and oxygen, particularly those mixtures wherein the hydrogen concentration is within the explosive range. The composition comprises a hydrogenation catalyst, preferably Pd dispersed on carbon, wherein the concentration of Pd is from about 1-10 wt.%, dispersed in a polymeric material matrix. As well as serving as a matrix to contain the hydrogenation catalyst, the polymeric material, which is substantially unreactive to hydrogen, provides both a diffusion restriction to hydrogen and oxygen, thereby limiting the rate at which the reactants (hydrogen and oxygen) can diffuse to the catalyst surface and thus, the production of heat from the recombination reaction and as a heat sink.
Patent DE-69831057-T2 (DE)
Inventor: COLE HAROLD
IPC: G01V3/12
Filed: 1998-01-16
Granted: 2006-06-01
Abstract: A system is provided for processing articles in a warehousing or merchandising operation wherein information bearing electronically coded labels are attached to the articles to be processed. The system uses the principle of electromagnetic communication in which an interrogator containing a transmitter generates an electromagnetic signal which is transmitted to electronic labels containing label receiving antennas. The electronic labels are attached to articles as they are processed. Each label antenna receives a proportion of the transmitted energy and operates a reply generation circuit connected either to the label receiving antenna or a separate label reply antenna with the result that an information bearing electromagnetic reply signal is radiated by the label.
Patent DE-69831794-T2 (DE)
Inventor: BARNES ALLEN C
IPC: C12N5/078
Filed: 1998-03-20
Granted: 2006-07-06
Abstract: A patient replica is created from a layered culture medium where solid culture medium is formed so that a discontinuity exists between the layers. An infusion port is provided in registration with the discontinuity so that a fresh unadulterated sample of patient blood can be infused into the discontinuity to form a thin layer of blood between the layers of culture medium. The thin layer obviates the requirement for any anticoagulant allowing blood-borne pathogens to be readily cultured without using broth. Further antibiotics or other drug samples may be placed on the surface of the culture medium above the blood layer so that the antibiotic can diffuse through the culture medium and reveal the sensitivities of the cultured pathogens. Other samples of pathogens or tissues can be placed on the surface of the culture medium so that effects of drugs or growth factors present in the patient blood can be observed thereby allowing the entrapped blood layer to act as a biological replica of the patient.