baber/WOPTO huggingface dataset:
Patent CA-2389595-C (CA)
Title: Improved synthesis of n,n-disubstituted-p-phenylenediamine
Inventor: TAN YUYING
IPC: C07C209/86
Filed: 2001-01-12
Granted: 2011-05-24
Abstract: An improved synthesis of N,N-disubstituted-p-phenylene-diamine (DSPDA) preferably di-n-butyl-p-phenylenediamine is disclosed. The improvement rests on the discovery that DSPDA and its salts are extremely sensitive to oxygen so that once the product DSPDA or its salt is formed, oxygen must be excluded from all manipulations.
Patent CA-2390535-C (CA)
Title: Curling garment brush retainer
Inventor: BUTTS EDMUND GENE
IPC: A41D13/00
Filed: 2000-09-14
Granted: 2008-12-02
Abstract: A retainer for a curling brush handle, adapted for use when suspended from a curling garment worn on the upper body, comprising a strip of flexible material adapted to be formed into an open loop configuration when suspended on a side of the garment, to engage with the distal end of the handle of a curling brush in order to provide on-ice support for the curler's body during delivery of a curling rock.
Patent CA-2402801-C (CA)
Title: Inhalateur
Inventor: RASMUSSEN JORGEN
IPC: A61M15/00
Filed: 2001-03-16
Granted: 2008-12-30
Abstract: L'invention concerne un inhalateur destiné à l'administration d'un médicament à partir d'un flacon lequel est compressible pour produire une dose d'un médicament. L'inhalateur comprend un logement (1) destiné à contenir un flacon (2), le logement présente un embout (5) permettant l'inhalation d'une dose de médicament fournie par le flacon (2) ainsi qu'un mécanisme (6) d'actionnement actionné par la respiration, destiné  à comprimer un flacon (2) contenu dans le logement (1) en réponse à une inhalation au niveau de l'embout (5). Le mécanisme d'actionnement (6) comprend un volet en forme de rabat (13) disposé sur un conduit (24, 32) s'étendant depuis l'embout (5) et agencé pour bloquer le flacon (2) à l'état comprimé, et réagissant à l'inhalation au niveau de l'embout (5) pour libérer le flacon (2) lorsque le niveau d'inhalation à l'embout chute sous un seuil prédéterminé.
Patent CA-2403286-C (CA)
Inventor: MAES DANIEL H
IPC: A61K8/36
Filed: 2001-12-20
Granted: 2009-10-13
Abstract: L'invention concerne des compositions contenant un mélange de sulfate de cholesterol et d'un exfoliant. Ledit exfoliant peut être un N-acetyl-D-glucosamine,un N-acetylgalactosamine, ou une combinaison de ceux-ci. La combinaison de sulfate de cholestérol et d'exfoliant améliore de manière surprenante la fonction barrière de la peau même lorsque l'activité de chaque composant est opposée à celle de l'autre. Du fait de l'aptitude à améliorer ou réparer la fonction barrière de la peau, l'invention concerne également des méthodes permettant d'améliorer ou de conserver une barrière de peau saine par application d'une quantité efficace de mélange de sulfate de cholestérol et d'exfoliant sur la peau. Ce mélange peut également être utile pour traiter ou prévenir un dommage cutané, ce dommage pouvant être provoqué par une fonction barrière de la peau compromise. Du fait de l'amélioration de la fonction barrière de la peau à l'aide de la combinaison de sulfate de cholestérol et d'exfoliant, l'apparition de lignes ou de rides est généralement réduite. L'invention concerne enfin l'amélioration d'états de peau sèche et rugueuse.
Patent CA-2405198-C (CA)
Inventor: WAKITANI TSUTOMU
IPC: B60L11/18
Filed: 2002-09-25
Granted: 2007-01-02
Abstract: An electric working machine includes electric motors, a movable speed adjustment lever, a potentiometer for producing a voltage variable in response to the movement of the lever, and a control unit for controlling the electric motors on the basis of the voltage. The lever is movable within a range including a neutral range, a working low speed range, a working middle speed range, and a high speed traveling range.
Patent CA-2407308-C (CA)
Inventor: LANG ALAN J
IPC: A61F2/16
Filed: 2001-05-02
Granted: 2010-07-13
Abstract: An intraocular lens for implantation in an eye of a patient includes a multifocal optic (12) and a movement assembly (14). The optic has a maximum add power which is less than the add power required for full near vision for a pseudophakic eye. The movement assembly is coupled to the optic (12) and is adapted to cooperation with the eye of the patient to effect accommodating movement of the optic in the eye. Lens systems including two optic and two movement assemblies are also provided. The intraocular lenses and lens systems are particularly useful when implanted in the eyes of a patient after removal of the natural lenses.
Patent CA-2407866-C (CA)
Title: Process for the synthesis of amine ethers from secondary amino oxides
Inventor: HAFNER ANDREAS
IPC: B01J27/122
Filed: 2001-05-17
Granted: 2010-07-20
Abstract: An amine ether of formula (A) wherein a is 1 or 2; and when a is 1, E is E';  when a is 2, E is L; E' is C1-C36 alkyl; C3-C18 alkenyl; C2-C18 alkinyl; C5-C18 cycloalkyl; C5-C18 cycloalkenyl; a radical of a saturated or unsaturated aliphatic bicyclic or tricyclic hydrocarbon of 7 to 12 carbon atoms; C2-C7alkyl or C3-C7alkenyl substituted by halogen; C7-C15aralkyl or C7-C15 aralkyl substituted by C1-C4 alkyl or phenyl; or E' is a radical of formula (VII) as explained in claim 1; T' is tertiary C4-C18alkyl or phenyl, each of which are unsubstituted or substituted by halogen, OH, COOR21 or C(O)-R22; or T' is C5-C12cycloalkyl; C5-C12cacloalkyl which is interrupted by at least one O or -NR18-; a polycyclic alkyl radical having 7-18 carbon atoms, or the same radical which is interrupted by at least one O or -NR18-; or T' is -C(G1)(G2)-T''; or C1-C18alkyl or C5-C12cycloalkyl substituted by F(I)T'' is hydrogen, halogen, NO2, cyano, or is a monovalent organic radical comprising 1-50 carbon atoms; or T'' and T' together form a divalent organic linking group completing, together with the hindered amine nitrogen atom and the quaternary carbon atom substituted by G1 and G2, an optionally substituted five- or six-membered ring structure; and all other residues are as defined in claim 1, are obtained in good yield from the corresponding N-oxyl hindered amine precursor by reaction with a hydrocarbon E1-H or H-L-H in the presence of an organic hydroperoxide and a catalytic amount of copper or a copper compound. The products of present process find utility as polymerization regulators and/or light stabilizers for organic material.
Patent CA-2414364-C (CA)
Inventor: HELLBERG RICHARD
IPC: H03F3/24
Filed: 2001-06-19
Granted: 2011-04-12
Abstract: L'invention porte sur un amplificateur composite comprenant un amplificateur de puissance principal (10) et un amplificateur de puissance auxiliaire (12) qui sont raccordés à une charge (14) sur un réseau de sortie Doherty (16). Des filtres (26, 28) sont prévus pour préfiltrer les signaux d'entrée de l'amplificateur de sorte que le signaux se rencontrant à la sortie de l'amplificateur principal varient essentiellement avec la même fréquence.
Patent CA-2422578-C (CA)
Inventor: BARDY GUST H
IPC: A61N1/39
Filed: 2001-09-14
Granted: 2013-02-26
Abstract: A unitary subcutaneous implantable cardioverter-defibrillator is disclosed which has a long thin housing in the shape of a patient's rib. The housing contains a source of electrical energy, a capacitor, and operational circuitry that senses the presence of potentially fatal heart rhythms. Provided on the housing are cardioversion/defibrillation electrodes located to deliver electrical cardioversion-defibrillation energy when the operational circuitry senses a potentially fatal heart rhythm. The unitary subcutaneous implantable cardioverter-defibrillator does not have a transvenous, intracardiac, epicardial, or subcutaneous electrode.
Patent CA-2424430-C (CA)
Title: Dispositif pour soulever et enlever des portes de fours a coke
Inventor: KNOCH RALF
IPC: C10B45/00
Filed: 2002-02-22
Granted: 2008-01-22
Abstract: L'invention concerne un dispositif permettant de soulever et d'enlever des portes de fours à coke, qui comprend une tête pour soulever les portes (1) pouvant être accouplée à des portes s'étendant verticalement d'un four à creuset horizontal, un dispositif d'entraînement (3) pour les mouvements d'ajustement de la tête pour soulever les portes (1) et une hotte d'aspiration, déplaçable au-dessus des portes du four le long dudit four à creuset horizontal. Selon l'invention, des éléments d'étanchéité (5) sont raccordés à la tête pour soulever les portes (1) et peuvent être déplacés de part et d'autre d'une porte de four (2) à ouvrir, à l'encontre de surfaces de contact frontales (6). Lesdits éléments d'étanchéité s'étendent sensiblement sur toute la hauteur de la porte du four (2), jusque dans la zone d'aspiration (4) de la hotte aspirante et forment un espace d'aspiration (8) pour les émissions provenant de la porte, au moment de l'ouverture de ladite porte du four (2).
Patent CA-2430045-C (CA)
Title: Polyurethane/ureas useful for the production of spandex and a process for their production
Inventor: LAWREY BRUCE D
IPC: C08G18/76
Filed: 2003-05-26
Granted: 2011-07-19
Abstract: Segmented polyurethane/ureas useful in the production of spandex are produced by chain extending an isocyanate-terminated prepolymer in the presence of a solvent. The isocyanate-terminated prepolymer is formed by reacting a stoichiometric excess of an isocyanate with an isocyanate-reactive component that includes more than 50 equivalent percent of a high molecular weight polyoxyalkylene diol having an unsaturation level no greater than about 0.015 meq/g and up to about 50 equivalent percent of a polytetramethylene ether glycol.
Patent CA-2434717-C (CA)
Inventor: JOHNSON BILL
IPC: G09F3/00
Filed: 2002-01-08
Granted: 2008-12-23
Abstract: A decorated ear tag for livestock is disclosed that comprises a pre-printed multi-layer label bonded to a suitable tag blank (102) to form a unitary finished tag. The resulting tag, and the information displayed thereby, are extremely resistant to deterioration by sunlight and other elements. In addition, the surface of the information panel of the resulting tag has a high slip factor that discourages obscurement of the displayed information by manure or other materials adhering to the tag.
Patent CA-2439381-C (CA)
Title: Paramagnetic nanoparticles
Inventor: HAASE MARKUS
IPC: A61K49/00
Filed: 2002-03-04
Granted: 2010-10-05
Abstract: The present invention relates to the preparation and use of nanoparticles, in particular paramagnetic nanoparticles, and their use as contrast enhancers for NMR-based methods of examination. A significant increase in contrast (e.g. from 100 to 200%) takes place according to the invention. An aqueous or organic synthesis leads to small nanoparticles which have a narrow size distribution and can also be advantageously used for many other industrial applications.
Patent CA-2440800-C (CA)
Title: Split-flow, vertical ammonia converter
Inventor: BLANCHARD KENNETH L
IPC: C01C1/02
Filed: 2003-09-12
Granted: 2011-06-07
Abstract: A vertical, fixed-bed ammonia converter wherein a fixed-bed catalyst zone is configured into two mechanically separated catalyst volumes and two gas streams that operate in parallel. The design maintains the ratio of gas flow to catalyst volume so that there is no catalyst effectiveness penalty. The catalyst beds and gas flow paths are configured so that gas flow is downward through each catalyst volume. Each fixed-bed catalyst zone in the present invention can hold the catalyst in an annular space formed between two concentric shrouds arranged around a shell and tube heat exchanger. The two catalyst beds associated with each zone are situated above one another along the length of an interstage heat exchanger. Pipes or conduits are disposed through the beds to effect the parallel gas flow configuration, or alternatively, annular flows are created via passages through the internal shrouds that contain the catalyst beds.
Patent CA-2443995-C (CA)
Title: Motifs d'expression de cellules endotheliales
Inventor: CARSON-WALTER ELEANOR
IPC: A61K39/00
Filed: 2002-04-10
Granted: 2014-06-03
Abstract: Afin de mieux comprendre l'angiogenèse des tumeurs, on a mis au point de nouvelles techniques pour isoler les cellules endothéliales (EC) et évaluer les motifs d'expression des gènes. Lorsque l'on a comparé les transcrits provenant des EC dérivés des tissus colorectaux normaux et malins aux transcrits provenant des cellules non endothéliales, on a identifié plus de 170 gènes exprimés de façon prédominante dans l'endothélium. La comparaison entre l'endothélium normal et celui dérivé des tumeurs a montré 79 gènes exprimés de façon différentielle, y compris 46 qui ont été spécifiquement élevés dans l'endothélium associé à la tumeur. Des expériences avec des gènes représentatifs de ce groupe ont montré que la plupart ont été exprimés de façon similaire dans l'endothélium du cancer primaire du poumon, du sein, du cerveau ainsi que dans des lésions métastasiques du foie. Les résultats ont montré que chez les humains l'endothélium néoplasique et celui normal se distinguent au niveau moléculaire, ce qui peut avoir une influence importante sur le développement des thérapies anti-angiogéniques de l'avenir.
Patent CA-2448251-C (CA)
Title: Metal complexes and therapeutic uses thereof
Inventor: FENTON RONALD RALPH
IPC: A61K31/4985
Filed: 2002-02-22
Granted: 2011-09-13
Abstract: A compound of formula I or a salt thereof (I) where M is selected from the group consisting of platinum (II), palladium (II), and copper(II);L1 is an intercalator moiety; andL2 is a bidentate ligand,provided that when L2 is other than a bidentate ligand containing an aryl or phenyl group, L2 is a chiral bidentate ligand.
Patent CA-2452447-C (CA)
Title: Antagonistic anti-htnfsf13b human antibodies
Inventor: GELFANOVA VALENTINA PAVLOVNA
IPC: A61P31/04
Filed: 2002-08-15
Granted: 2012-04-24
Abstract: Human monoclonal antibodies that specifically bind to TNFSF13b polypeptides are disclosed. These antibodies have high affinity for hTNFSF13b (e.g., KD =  10-8 M or less), a slow off rate for TNFSF13b dissociation (e.g., Koff = 10-3 sec-1 or less) and neutralize TNFSF13b activity in vitro and in vivo. The antibodies of the invention are useful in one embodiment for inhibiting TNFSF13b activity in a human subject suffering from a disorder in which hTNFSF13b activity is detrimental. Nucleic acids encoding the antibodies of the present invention, as well as, vectors and host cells for expressing them are also encompassed by the invention.
Patent CA-2453151-C (CA)
Title: Dispositif pour delivrer des substances
Inventor: HANSEN BERND
IPC: A61J3/00
Filed: 2002-07-15
Granted: 2009-10-20
Abstract: L'invention concerne un dispositif permettant de délivrer des substances, comprenant un récipient distributeur (1) contenant la substance concernée, muni d'une unité de fermeture (3) qui présente une canule (11) pour la substance à délivrer, dont l'extrémité extérieure (15) fait saillie de l'unité de fermeture (3). Il est prévu un système de sécurité (5, 17) pouvant passer d'un état de protection où il recouvre l'extrémité extérieure (15) de la canule (11), à un état d'utilisation prévu pour déverser la substance hors de la canule (11).
Patent CA-2457856-C (CA)
Title: Meso-tetraphenyl chlorines sulphonees et leur utilisation comme agents therapeutiques
Inventor: BERG KRISTIAN
IPC: A61P31/12
Filed: 2002-08-30
Granted: 2011-01-25
Abstract: La présente invention concerne des agents de photosensibilisation obtenus par réduction d'une seule double liaison au niveau du macrocycle de prophyrine d'une méso-tétraphénylporphyrine sulfonée, de préférence, une méso-tétraphénylporphyrine disulfonée telle que la TPPS¿2a?. Les méso-tétraphénylchlorines sulfonées ainsi obtenues comprennent des composés de formule (I) (où X représente -SO¿3?H; n, p, q et r représentent chacun indépendamment 0 ou 1; et la somme de n, p, q et r représente un entier compris entre 1 et 4, de préférence au moins 2, par exemple 2 ou 4), des isomères et des mélanges d'isomères. Les composés selon l'invention et leurs sels pharmaceutiquement acceptables sont notamment utilisés en tant qu'agents de photosensibilisation dans l'internalisation photochimique de molécules et dans la thérapie photodynamique.
Patent CA-2457908-C (CA)
Title: Fuel cell system and method for recycling exhaust
Inventor: BARRETT SCOTT NEIL
IPC: H01M8/04
Filed: 2002-08-30
Granted: 2011-08-09
Abstract: A fuel cell system and method in which fuel exhaust from a fuel cell stack is recycled to a fuel side stack inlet by way of a fuel exhaust recycle line and a jet pump. A  primary fuel stream at an inlet provides the motive power for the jet pump and the jet pump has a variable nozzle geometry to entrain variable proportions of fuel exhaust in the primary fuel in order to maintain desired fuel flow volumes across the anode-side of the fuel cell stack on turndown of the stack and to facilitate enhanced fuel utilization by the stack.
Patent CA-2458007-C (CA)
Inventor: SHILLINGBURG CURTIS W
IPC: E04B2/02
Filed: 2004-02-17
Granted: 2008-01-15
Abstract: A modular wall block is adapted for being assembled together with a number of other blocks in stacked courses to form a retaining wall. The wall block has a front and rear, top and bottom, and opposing sides. At least one of the opposing sides defines a generally L-shaped vertical slot. A course connector is received in the vertical slot, and includes first and second ends joined together by a setback spacer. The first end extends in an x-direction and a y-direction, and defines a generally L-shaped structure received in the L-shaped slot and restricting forward, rearward, and outward movement of the course connector. The second end of the course connector extends outwardly in a z- direction beyond one of the top and bottom of the wall block to engage one of the number of other blocks in an upper or lower course. The setback spacer locates the second end of the course connector a spaced distance from the first end to position the wall block in the retaining wall relative to the other blocks in the upper or lower course.
Patent CA-2462099-C (CA)
Inventor: PALSSON BERNHARD O
IPC: G16B5/00
Filed: 2002-10-24
Granted: 2013-01-08
Abstract: The invention provides an in silica model for determining a S. cerevisiae physiological function. The model includes a data structure relating a plurality of S. cerevisiae reactants to a plurality of S. cerevisiae reactions, a constraint set for the plurality of S. cerevisiae reactions, and commands for determining a distribution of flux through the reactions that is predictive ofa s. cerevisiae physiological function. A model of the invention can further include a gene database containing information characterizing the associated gene or genes. The invention further provides methods for making an in silica S. cerevisiae model and methods for determining a S. cerevisiae physiological function using a model of the invention.
Patent CA-2465640-C (CA)
Title: Process for forming amorphous atorvastatin
Inventor: LORENZ DOUGLAS ALAN
IPC: A61K9/20
Filed: 2004-04-29
Granted: 2008-07-15
Abstract: Forming amorphous atorvastatin comprises the steps of dissolving atorvastatin in a hydroxylic solvent, followed by rapidly evaporating the solvent. In another aspect, a composition comprises particles of amorphous atorvastatin and a core.
Patent CA-2469172-C (CA)
Title: Method and apparatus for automatic determination of performance problem locations in a network
Inventor: DENBY LORRAINE
IPC: H04L12/24
Filed: 2004-05-28
Granted: 2008-10-07
Abstract: A network monitoring and analysis system is configured to include a root cause analysis function that permits the automatic determination of performance problem locations in a network of a communication system comprising a plurality of endpoint devices. Test communications are generated in the system in accordance with a selected pattern, which may be based on a flow matrix, and end-to-end path measurement data is collected utilizing the generated test communications. The end-to-end path measurement data is transformed to produce a plurality of performance indicators comprising a performance indicator for each of a plurality of non-end-to-end paths defined at least in part by the selected pattern.
Patent CA-2473433-C (CA)
Inventor: HASEGAWA SHUMPEI
IPC: F02B75/18
Filed: 2004-07-09
Granted: 2007-09-25
Abstract: To reduce the number of parts, improve the mountability and maintainability, and allow size and weight reduction in an engine having a crankshaft, a crankcase having a plurality of bearing portions for rotatably supporting the crankshaft, each of the bearing portions being dividable along a divisional plane arranged on the axis of the crankshaft, cylinder barrels connected to the crankcase and having cylinder bores, and cylinder heads connected to the cylinder barrels. The cylinder heads are integrated with portions of the cylinder barrels forming at least the cylinder bores to form cylinder blocks. The cylinder blocks and the crankcase are fastened together by a plurality of fastening bolts having axes parallel to the axes of the cylinder bores and extending through at least the cylinder blocks, with a compressive structure in the axial direction of the fastening bolts.
Patent CA-2475859-C (CA)
Inventor: TERRY STEPHEN E
IPC: H04W28/18
Filed: 2003-02-11
Granted: 2013-04-16
Abstract: Data of a time transmission interval is to be transmitted in a wireless communication system. The wireless communication system uses adaptive modulation and coding and has automatic repeat request mechanism. A  transmission time interval has a plurality of transport block sets. The transport block sets are transmitted with a first specified modulation and coding scheme. Each transport block set is received and a determination is made as to whether the transport block sets meet a specified quality (50).  When the specified quality is not met, a repeat request is transmitted (51).  The specified modulation and coding scheme is changed to a second specified modulation and coding scheme that may support a reduced number of TBS's within the transmission time interval. In response to the repeat request, at least one of the transport block sets is retransmitted. The retransmitted transport block set is received. The retransmitted transport block set may be combined with a corresponding previously received transport block set (51).
Patent CA-2482004-C (CA)
Inventor: THOMAS BRIAN F
IPC: C07D231/12
Filed: 2003-04-14
Granted: 2011-06-07
Abstract: L'invention concerne des composés qui sont des analogues amides de SR141716A présentant une sélectivité de récepteur unique CB1 et assurent des caractéristiques de liaison économisant les WIN. L'invention traite aussi de compositions pharmaceutiques contenant ces composés et de leur utilisation dans un procédé de traitement des troubles liés au récepteur CB1, comme l'obésité, la schizophrénie, les troubles de la mémoire et l'abus de marijuana.
Patent CA-2484917-C (CA)
Title: An electronic learning device for an interactive multi-sensory reading system
Inventor: KELLEY MIRIAM
IPC: G09B11/00
Filed: 2003-05-30
Granted: 2011-07-12
Abstract: An electronic learning device configured to receive in a predetermined orientation a book (2). The book includes a first (16a, 44) and second (16b, 46) page. The device further includes a base (122), cover (114) and book mounting assembly (118). A controller is in electrical communication with a position sensor (232) for detection the presence of a selector.
Patent CA-2486439-C (CA)
Inventor: TRANELL GABRIELLA MARIA
IPC: C21C7/076
Filed: 2003-03-17
Granted: 2008-10-14
Abstract: L'invention concerne une scorie à base de silicate de calcium ayant une teneur en phosphore inférieure à 3 ppmw. L'invention concerne, en outre, un procédé de production d'une scorie à base de silicate de calcium à basse teneur en phosphore, dans lequel la scorie à base de silicate de calcium fondu est traitée à l'aide d'un alliage de ferrosilicium fondu dans un récipient, le phosphore contenu dans la scorie étant transférée dans l'alliage de ferrosilicium, et une scorie à base de silicate de calcium à basse teneur en phosphore étant extraite du récipient.