baber/WOPTO huggingface dataset:
Patent CA-2498787-A1 (CA)
Title: Antibody for adcc and inducing cytokine production
Inventor: DE ROMEUF CHRISTOPHE
IPC: A61P35/00
Filed: 2003-09-15
Abstract: Chimeric or human monoclonal antibody (MAb) produced in a cell that is chosen for its glycosylation properties on the Fc fragment, or in which the glycan structure has been modified ex vivo.  Chimeric or human monoclonal antibody (MAb) produced in a cell that is chosen for its glycosylation properties on the Fc fragment, or in which the glycan structure has been modified ex vivo. MAb are obtained by: (a) selection for a level of FcgammaRIII (CD16)-type ADCC (= antibody-dependent cellular cytotoxicity) over 100% at 10 ng/ml, compared to the same antibody produced in CHO (Chinese hamster ovary) cells; and  (b) selection for ability to induce production of at least one cytokine (I) in Jurkat CD16 cells (or effector cells of the immune system that express CD16) over 60, best over 200,% at 10 ng/ml, compared with the same antibody expressed in CHO. An Independent claim is also included for antibodies (Ab1) produced in a rat myeloma cell line, particularly YB 2/0, selected in the same way.
Patent CA-2500216-A1 (CA)
Title: Elements structuraux formes de materiaux moulables
Inventor: VAN ERP GERARDUS MARIA
IPC: E04C5/20
Filed: 2003-09-25
Abstract: L'invention porte sur des éléments structuraux formés de matériaux moulables et comportant: plusieurs éléments tubulaires de plastique renforcé de fibres; plusieurs entretoises de plastique renforcé de fibres s'étendant entre les susdits éléments tubulaires; plusieurs éléments d'interconnexion de plastique renforcé de fibres disposés selon différentes orientations par rapport auxdites entretoises et les recoupant; et un matériau moulable enrobant l'ensemble des susdits éléments.
Patent CA-2500888-A1 (CA)
Inventor: MATSUMOTO TOSHIFUMI
IPC: C07D405/06
Filed: 2003-10-01
Abstract: L'invention porte sur un composé d'isoquinoline représenté par la formule générale (I), sur ses isomères optiquement actifs, ses sels acceptables d'un point de vue pharmaceutique, ses produits d'addition d'eau, ses hydrates et ses solvates. L'invention porte également sur un agent prophylactique et/ou thérapeutique d'une maladie provoquée par l'hyperfonction de la poly(ADP-ribose)synthase contenant le composé précité, et sur un inhibiteur de la poly(ADP-ribose)synthase. Ce composé est également utile comme agent prophylactique et/ou thérapeutique dans la formation d'un infarctus cérébral en phase aiguë. Ce composé est, de plus, utile comme agent prophylactique et/ou thérapeutique en vue d'améliorer les symptômes nerveux accompagnant la formation d'un infarctus cérébral, notamment, en phase aiguë.
Patent CA-2502554-A1 (CA)
Inventor: CHIDAMBARAN RAVI
IPC: B01D24/00
Filed: 2003-10-16
Abstract: This invention presents an ion exchange media including a plurality of cation exchange zones (C) and anion exchange zones (A) in flow paths that are contained in a substantially nonporous resin transport framework. During electrodeionization and other potential applications the ion exchange media of the invention prevents unfavorable water splitting at resin-membrane interfaces and encourages water splitting at resin-resin interfaces where the water splitting may be constructively used to regenerate the resin.
Patent CA-2503404-A1 (CA)
Title: Configurations and methods of acid gas removal
Inventor: MAK JOHN
IPC: B01D53/14
Filed: 2003-12-11
Abstract: A plant includes a vacuum stripper (118) that receives a lean hydrogen sulfide-containing physical solvent (32) and in which substantially hydrogen sulfide-free stripping gas (51,52) is provided by at least one of a high-pressure flash vessel (110) and a medium pressure flash vessel (112). Contemplated configurations advantageously extend the range of use for physical solvents to treat sour gas comprising carbon dioxide and hydrogen sulfide, and can be used to meet most pipeline specification of 4 ppm hydrogen sulfide.
Patent CA-2505461-A1 (CA)
Inventor: MORRISON MATTHEW M
IPC: A61B17/88
Filed: 2003-11-10
Abstract: A device for supporting and/or assisting in bone fusion, particularly in the spine, is described. A plate member is provided, along with two or more attachment members that are anchorable to bones. In one embodiment, the plate member has a slot near one end and an aperture at another end. The attachment members include threaded posts for connection to the plate member via the latter's slot(s) and aperture(s). Alternatively, attachment members need not have a threaded post, and attachment members may be connected to the plate member via a bone bolt or similar fixation member. The slot(s) allow a single plate member to be used for a variety of operative situations and anatomies. A  device for repositioning bones and a method for using the disclosed devices is also described.
Patent CA-2507452-A1 (CA)
Title: Single-use cover system for electromagnetic treatment applicator
Inventor: GEORGE FRANK R
IPC: A61N1/40
Filed: 2003-12-01
Abstract: An electromagnetic treatment device (200) includes a treatment pad (206) and a generating unit (218) connected to the treatment pad by a coaxial cable (205 ). The treatment pad has an antenna (211) on one side of the treatment pad. The generating unit includes a start/stop button (220), a radio frequency generator (208) and a covertest board (212). A single-use cover system (201) includes the electromagnetic treatment device and a disposable cover (203) including a RFID tag (202). The single-use cover system verifies that the disposable cover is placed over the treatment pad properly and that the disposable cover has not been used previously.
Patent CA-2508002-A1 (CA)
Title: Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents
Inventor: UBILLAS ROSA
IPC: C07C49/755
Filed: 2003-12-04
Abstract: The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid Compound. The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a cancer cell or neoplastic cell, or for inducing apoptosis in a cancer or neoplastic cell. The compounds, compositions, and methods of the invention are further useful for treating or preventing a fungal infection.  The compounds, compositions, and methods of the invention are also useful for inhibiting the growth of a fungus.
Patent CA-2508961-A1 (CA)
Title: Method and device for injection molding
Inventor: ENJOJI NAOYUKI
IPC: B29C45/28
Filed: 2003-12-10
Abstract: A method for injection molding comprises the following steps: a step of preparing a first mold (41), a second mold (46), and a third mold (47), a st ep of sandwiching a separator single body (16) by the first mold (41) and the second mold (46), a step of injecting silicone rubber (59) into a front-side cavity (50) through a gate (52) to form a front-side formed layer (32), a st ep of replacing the second mold (46) with the third mold (47) while the front- side formed layer (32) is soft, and a step of penetrating the front-side formed layer (32) by injection pressure of the silicone rubber (59) injected through the gate (52), filling the silicone rubber (59) into a back-side cavity (63) through a penetration hole (30), and forming a back-side formed layer (34).
Patent CA-2513515-A1 (CA)
Inventor: KASSELMANN GERD
IPC: B29C48/32
Filed: 2003-12-19
Abstract: The invention relates to a take-off unit for a film produced by means of a blowing method. Said take-off unit comprises air deflector bars and divertin g rollers, which, as a rule, reverse in opposition, whilst, as a rule, carryin g out rotational movements about a common axis. The disclosed take-off unit is characterised in that at least one of the air deflector bars has a surface a t least partly made from a sintered material.
Patent CA-2514110-A1 (CA)
Title: Handheld medical reference application with integrated dosage calculator
Inventor: ROSENBLOOM MARK
IPC: G06F19/00
Filed: 2004-01-26
Abstract: A medical information device may include a general purpose computer such as a handheld computer, configured with a plurality of medical and drug information content pages and a reader application configured to display the medical and drug information content pages. To access the drug and medical information content pages, the reader may generate a plurality of parameter strings in response to user-selected medical and drug information. The medical information device may also include a drug dosing calculator application configured to receive at least one of the parameter strings generated by the reader application and to return dosing information to the reader application.  The parameter string or strings may include a drug dosing parameters corresponding to a user-selected medical condition and a user-selected drug and/or drug dosing parameters corresponding to medical and drug information included on a selected medical and drug information content page. The medical information device may also include a general medical calculator application configured to receive at least one of the parameter strings generated by the reader application and to return appropriate calculated results to the reader application.
Patent CA-2514530-A1 (CA)
Title: Upright vacuum cleaner incorporating telescopic wand assembly with trigger operation
Inventor: FISCHER RICHARD J
IPC: A47L5/28
Filed: 2005-08-03
Abstract: An upright vacuum cleaner includes a housing having a nozzle assembly and a canister assembly. A suction generator and a dirt collection vessel are both carried on the housing. The vacuum cleaner also includes a detachable telescopic wand assembly. That wand assembly includes a first wand section, a second wand section, a wand lock for securing the two wand sections together and a trigger actuator for operating the wand lock.      The trigger actuator is located remote from the wand lock on the wand assembly.
Patent CA-2516749-A1 (CA)
Title: Flow field design
Inventor: ONG ESTELA T
IPC: H01M8/04
Filed: 2005-08-18
Abstract: A flow field (38) forming one wall of a channel (36) in a flow field plate (18) of a solid oxide fuel cell (10), the flow field includes a flat substrate (40) having a patterned array of differently-shaped flow barriers (52, 64, 66) projecting from the substrate into the channel, the flow field channel decreases in cross-sectional area in a flow direction.
Patent CA-2516841-A1 (CA)
Inventor: ANDERSEN FRANCK-UWE
IPC: H04L29/06
Filed: 2003-02-25
Abstract: The invention relates to a method for separating IP packets which can be allocated to specific groups in a packet-based mobile radio network. All IP packets entering into the mobile radio network are tested in a first authorized network element of the mobile radio network with respect to allocation to at least one group. A group-specific marking is produced, at least for IP packets which can be allocated to a specific group, in a field of a header of at least one packet, especially one of said IP packets.
Patent CA-2517052-A1 (CA)
Title: Polyvalent immunogen
Inventor: HAYNES BARTON F
IPC: A61K39/00
Filed: 2004-02-26
Abstract: The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for use in such a method.
Patent CA-2518011-A1 (CA)
Inventor: PERKINS ROBERT
IPC: A61M5/315
Filed: 2004-03-03
Abstract: The invention relates to a drive mechanism for use in a drug delivery device comprising: a housing (2); a dose dial sleeve (40) having a helical thread of a first lead; and a two-part piston rod (14). The said two-part piston rod (14) comprises an outer part (18) having a helical thread of a second lead and an inner part (16) having a helical thread of a third lead, whereby the first lead of the thread of the dose dial sleeve (40) is equal to the sum of the second lead of the thread of the outer part (18) of the piston rod (14) and the third lead of the thread of the inner part (16) of the piston rod (14).
Patent CA-2518088-A1 (CA)
Inventor: NIELSEN MORTEN BENT
IPC: H04R25/02
Filed: 2003-03-06
Abstract: La présente invention a trait à une unité de combinaison destiné à être fixé à une prothèse auditive comportant un adaptateur et un accessoire, présentant des passages de guidage d'accouplement, des faces de pression d'assemblage respectives (14, 29) adjacentes aux passages de guidage et des faces de pression de démontage respectives (13, 30), également adjacentes aux passages de guidage. L'adaptateur (2) comporte un sabot, c'est à dire une structure de type gaine, adapté à entourer en partie la portion inférieure de la prothèse auditive. L'accessoire (3) peut comprendre un récepteur à modulation de fréquence miniaturisé. L'extérieur du boîtier de récepteur (22) est conformé pour épouser la forme extérieure de l'adaptateur de sorte que les parois respectives soient affleurées lors de l'assemblage des parties. L'unité de combinaison (1) de l'adaptateur et de l'accessoire est facilement assemblée et facilement démontée, et est très compacte. L'invention a trait à une unité de combinaison, comportant le sabot et l'accessoire, ainsi qu'un procédé pour la fixation d'un accessoire à une prothèse auditive.
Patent CA-2519383-A1 (CA)
Title: Communications conduit connector
Inventor: EDWARDS JOHN R
IPC: H02G3/04
Filed: 1998-03-17
Abstract: A communications conduit connector mounting device comprising a support member having a forwardly directed front surface and a rearwardly directed rear surface spaced from the front surface, the support member having a thickness defined between the front surface and the rear surface, an aperture extending transversely through the support member throughout the thickness of the support member opening through both the front surface and the rear surface, a slotway extending transversely through the support member throughout the thickness of the support member open through both the front surface and the rear surface laterally from the aperture to a side of the support member. Preferably, the mounting device includes a hook member coupled to the support member for suspending the support member.
Patent CA-2520681-A1 (CA)
Title: Microwave brazing of airfoil cracks
Inventor: GARIMELLA BALAJI RAO
IPC: B23P6/04
Filed: 2005-09-22
Abstract: A gas turbine engine includes alternating rows of rotary airfoils or blades and static airfoils or vanes. The canes are made of a base metal, such as cobalt or nickel superalloy. It a crack forms in one of the vanes, a braze alloy is applied to the crack. The braze alloy is a powdered slurry. The braze alloy includes approximately 50 to 100% of a base material and approximately 0 to 50% of a braze material. The base material of the braze alloy has the same composition as the composition of the base metal of the vane. The airfoil is then exposed to microwaves which melt the braze alloy in preference to the base metal to repair the crack in the vane.
Patent CA-2522725-A1 (CA)
Title: Polynucleotides for the detection of listeria monocytogenes
Inventor: PLANTE DANIEL
IPC: C12Q1/68
Filed: 2004-04-19
Abstract: Polynucleotide primers and probes for the amplification and detection of Listeria monocytogenes in samples are provided. The primers and probes can be used in real time diagnostic assays for rapid detection of Listeria monocytogenes in a variety of situations. Kits comprising the primers and probes are also provided.
Patent CA-2522925-A1 (CA)
Title: Transgenic expression of a phytochrome a gene
Inventor: WU RAY
IPC: C12N15/87
Filed: 2004-04-29
Abstract: An isolated nucleic acid construct including a nucleic acid molecule encoding a light-labile, phytochrome A, a light-inducible promoter which is 5~ to the nucleic acid molecule encoding a light-labile, phytochrome A, and a terminator region which is 3~ to the nucleic acid molecule encoding a light-labile, phytochrome A is disclosed. Methods for regulating a plant~s canopy architecture and regulating a plant~s seed yield, which involve transgenic plants or transgenic plant seeds including an isolated nucleic acid construct according to the present invention, are also disclosed.
Patent CA-2523205-A1 (CA)
Title: Cannabinoid receptor ligands and uses thereof
Inventor: CARPINO PHILIP ALBERT
IPC: A61P3/04
Filed: 2004-04-13
Abstract: Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein.
Patent CA-2523665-A1 (CA)
Inventor: REIMANN ROBERT C
IPC: B60H1/00
Filed: 2004-04-26
Abstract: A module for a bus rooftop air conditioner is self contained in that it has all the necessary components including a compressor (27), if desired, which when supplied with electrical power, can provide conditioned air to the passenger compartment of a bus. In addition, an electrically powered heater (24) is provided in the air flowstream such that heated air can also be supplied to the passenger compartment when desired. Multiple units provide for incremental capacity requirements to be met as well as limp home capabilities.
Patent CA-2530443-A1 (CA)
Inventor: HARTIG KLAUS
IPC: C03C17/36
Filed: 2004-06-24
Abstract: The invention provides a substrate bearing a low-emissivity coating. The low-emissivity coating comprises at least one graded film region. In certain embodiments, at least one graded film region is provided between the two infrared-reflective layers of a double-type low-emissivity coating. The graded film region has a substantially continuously decreasing concentration of a first dielectric material and a substantially continuously increasing concentration of a second dielectric material. Also provided are methods of depositing such low emissivity coatings and substrates bearing these coatings.
Patent CA-2533542-A1 (CA)
Title: Method of determining sperm capacitation
Inventor: KOPF GREGORY S
IPC: C12Q1/00
Filed: 2004-07-23
Abstract: This invention describes unique patterns of distribution of ganglioside GM1, in non-capacitated sperm and demonstrates that the pattern of distribution of GM1 undergoes changes that can be correlated with the process of capacitation and/or with acrosornal exocytolsis. Accordingly, the present invention discloses a method for determining the ability of sperm to respond to capacitation and/or acrosomal exocytosis stimuli. The method comprises determination of distribution pattern for GM1. The method can be used for both diagnostic and predictive purposes when assessing male reproductive fitness, and can also be used to assess the effects on sperm of cryoprotective agents and protocols, and contraceptive agents.
Patent CA-2534202-A1 (CA)
Title: Lipid glycerides for the treatment of neurodegenerative conditions involving demyelination
Inventor: LEACH MICHAEL J
IPC: C07C67/14
Filed: 2004-08-13
Abstract: A method is provided for treating a patient in need of therapy for a neurodegenerative disease comprising administering to that patient a therapeutically effective dose of a lipid glyceride comprising a glycerol moiety and a fatty acid moiety, the fatty acid moiety being selected from the group consisting of .gamma.-linolenic acid, dihomo-.gamma.-linolenic acid and arachidonic acid characterised in that the selected fatty acid moiety is attached to the glycerol moiety at its sn-2 position. Preferably the method is that wherein the lipid is administered for a duration and at a dose sufficient to maintain or elevate TGF-.beta.1 levels in the patient to therapeutic levels.
Patent CA-2537679-A1 (CA)
Title: Electronic circuit prototyping apparatus
Inventor: CHAN ERIC K D
IPC: H05K7/04
Filed: 2006-02-24
Abstract: The electronic prototyping apparatus facilitates circuit developer or student learning electronic circuit building for educational purposes to build reliable electronic circuits. A plurality of standard electronic circuit modules are provided on a master printed circuit. A configuration of eyelet connection terminals to the circuit modules is formed in a predetermined area of the master printed circuit. An intermediate breadboard is mounted below the predetermined area such that the eyelet terminals are in registry with the tie points of the intermediate breadboard. A  prototyping breadboard is located immediately adjacent to the predetermined area of the master printed circuit.
Patent CA-2542999-A1 (CA)
Inventor: WICKSTEAD JAMES C
IPC: A61B5/00
Filed: 2004-10-19
Abstract: The present invention provides a funnel collector for use with a sample testing device. The funnel collector collects and holds a fluid sample in order to place the sample in immediate contact with a diagnostic test strip, which reacts with the sample in a known fashion.
Patent CA-2543064-A1 (CA)
Inventor: KABS KLAUS
IPC: C08F20/14
Filed: 2004-09-15
Abstract: Production of plastics moldings with a thickness of 30-200 mm comprises thermal polymerization of a mixture of a polymethyl (meth)acrylate syrup (I) free from residual initiator and a mixture of methyl methacrylate (MMA) and usual additives and an olefinic carbocyclic compound (II). Independent claims are also included for the following: (1) plates of PMMA (polymethyl methacrylate) produced by this process; (2) production of (I), free from residual initiator, by polymerization of a mixture of 100 parts MMA and 0.05-0.1 part peroxydicarbonate to 10-30% conversion.
Patent CA-2544018-A1 (CA)
Title: Compositions and methods to reduce mutagenesis
Inventor: CIRZ RYAN
IPC: G01N33/50
Filed: 2004-11-19
Abstract: The present invention provides methods and compositions for said inhibition of drug resistance. In one embodiment, said invention provides methods and compositions for said inhibition of antibiotic resistance. The invention generally involves said administration of achaogens, agents that inhibit said mutational process, to inhibit said evolution of drug resistance. Also, described herein are compositions that are suitable for use as achaogens.
Patent CA-2544527-A1 (CA)
Inventor: PAYNE STEPHEN R
IPC: G06F3/12
Filed: 2004-11-09
Abstract: The present invention relates to methods for providing periodic status updates from a printer to a host system, and a printer capable of providing such status updates. A printer in accordance with the present invention includes means for generating printer status information and means for automatically sending the printer status information to the host system at periodic time intervals, without the need for a status request from the host system or a status change at the printer. The time interval and/or the status information may be configured via the host system.
Patent CA-2546411-A1 (CA)
Inventor: BEGOUNOV STANISLAV
IPC: C23C16/509
Filed: 2003-11-18
Abstract: Le procEdE et le dispositif concernent le traitement de surface en continu de la surface d'un objet allongE filiforme au moyen d'un plasma crEE par une dEcharge Electrique sous pression ambiante. Le dispositif (100) comprend un corps tubulaire (2), dans lequel est mEnagE un canal (1) au moins partiellement ouvert A ses deux extrEmitEs pour le passage de l'objet allongE (A) selon un axe de dEfilement sensiblement parallEle A l'axe longitudinal du canal (1), des moyens (3) pour gEnErer un flux de plasma neutre sous un angle dEterminE par rapport A l'axe longitudinal dans au moins une partie (10) du corps (2), et des moyens pour confiner le flux de plasma dans cette partie (10) au moins pendant que l'objet allongE traverse cette partie du corps du canal. Le dispositif permet aussi de varier l'effet du traitement en ajoutant des additifs nEcessaires dans le plasma et/ou directement dans une zone de traitement et en utilisant les diffErentes zones du plasma contenant des particules dotEes de diffErent niveau d'Energie.