Patent SG-11201805618U-A (SG)
Title: Process for preparing a crassocephalum crepidioides extract, extract prepared thereby and use of the extract
Inventor: TSAI DAI-HUA
IPC: A61K36/28
Filed: 2015-12-31
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2017/116476 Al 6 July 2017 (06.07.2017) WIPO I PCT 11111111111111011101111111111101011111011101110111111111110111111111111111111110111111 W O 20 17 / 116 47 6 Al (51) International Patent Classification: A61K 36/28 (2006.01) A61P 35/00 (2006.01) A61K 31/513 (2006.01) (21) International Application Number: PCT/US2015/068337 (22) International Filing Date: 31 December 2015 (31.12.2015) Filing Language: English Publication Language: English Applicants: DEVELOPMENT CENTER FOR BIO- TECHNOLOGY; No. 101, Lane 169, Kangning St., Xizhi Dist., New Taipei City, 22180 (TW). DCB-USA LLC [US/US]; 1007 North Orange Street, 9th Floor, New Castle County, Wilmington, DE 19801 (US). (72) Inventors: TSAI, Dai-Hua; 5F., No.45-1, Anju St., Da'an Dist., Taipei City, 106 (TW). LAI, Tzung, Hsien; 5F., No 328-1, Jinhu Rd., Neihu Dist., Taipei City, 114 (TW). CHAN, Tsui Hsu; 9F., No.250, Sec. 1, Longmi Rd., Bali Dist., New Taipei City 249 (TW). CHUNG, Yuh Shan; Rm. 2, 6F., No.27, Ln. 131, Wenhua N. Rd., Sanchong Dist., New Taipei City 241 (TW). HSU, Li-Chuan; No.16, Ln. 172, Xianghe Rd., Tanzi Dist., Taichung City 427 (TW). (74) Agent: KING, Anthony; WPAT, P.C., 2301 Dupont Drive, Suite 510, Irvine, CA 92612 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (25) (26) (71) (54) Title: PROCESS FOR PREPARING A CRASSOCEPHALUM CREPIDIOIDES EXTRACT, EXTRACT PREPARED = THEREBY AND USE OF THE EXTRACT (3) 1730 100 20 21 22 23 24 25 26 27 23 Figure 1 (57) : The present invention provides a process for the preparation of a Crassocephalum crepidioides extract, and the ex- tract prepared thereby. The present invention further relates to a pharmaceutical composition/combination comprising the Crasso- cephalum crepidioides extract. The use of the extract and the composition/combination comprising the extract in the prevention or treatment of cancer is also provided.