baber/WOPTO huggingface dataset:
Patent JP-2000511783-A (JP)
Title: ランダムプライマーまたは定義プライマーを用いるポリヌクレオチド配列の組換え
IPC: C12Q1/68
Filed: 1998-03-25
Abstract: (57)【要約】
プライマーオリゴヌクレオチドのポリメラーゼ触媒伸長に基づくポリヌクレオチド配列のインビトロ変異誘発および組換えのための方法が開示される。この方法は、テンプレートポリヌクレオチド（単数または複数）をランダム配列プライマーまたは定義配列プライマーでプライミングして、低レベルの点変異を有する短いDNAフラグメントのプールを作製することを含む。DNAフラグメントは、変性、続いてアニーリングおよびさらなる酵素触媒DNA重合に供される。この手順は、最初のテンプレートポリヌクレオチドの変異体を含む完全長遺伝子を生成するために十分な数の回数で反復される。これらの遺伝子は、ポリメラーゼ連鎖反応によりさらに増幅され、そしてコードされるタンパク質の発現のためのベクターにクローニングされ得る。
Patent MX-153882-A (MX)
Inventor: BENCKHUIJSER JAN GERRIT
IPC: A01K13/00
Filed: 1982-03-09
Abstract: Protective blanket for hoofed and domestic animals, in particular horses and dogs, to protect against the influences of cold in cold weather or due to evaporation of the skin moisture after physical exertion, and for thermal treatment of certain ailments, e.g. influenza or kidney trouble. Woolen or linen blankets have the disadvantage of not giving off the evaporation moisture and do not provide warmth when wet. The protective blanket according to this invention provides better heat protection and has a therapeutic effect due to the fact that it consists of two mutually movable layers of a knit fabric (6) made of nonhygroscopic synthetic fibers fit for generating static electricity and with a mesh of 50-125/cm2. For choice, the blanket contains a synthetic foam lining permeable to air between the two layers of fabric (6). The drawing shows the outside of a horse blanket with a neck rim (31) at the head end and a rear rim (32) with a loop (40) to accommodate the tail. The cutout (41) at the neck rim produces two blanket ends to fit around the breast (FIG. 5 ).
Patent NZ-206890-A (NZ)
Title: Sulphenyl nitromethane derivatives and pesticides
Inventor: HARRIS M
IPC: A01N43/86
Filed: 1984-01-19
Abstract: Sulphenyl nitromethane derivatives of formula:in which R<sup>1</sup> represents an alkyl group or a cycloalkyl-alkyl group; and R<sup>2</sup> represents an alkyl group optionally substituted by one or more halogen atoms or an aryl group optionally substituted by one or more halogen atoms or by one or more alkyl or alkoxy groups, exhibit pesticidal, in particular insecticidal activity. They are prepared by reacting the corresponding nitromethylene carboxylate with a sulphenyl halide R<sup>2</sup>- S - Hal in the presence of a base.
Patent NZ-216835-A (NZ)
Title: Process for the sulphation of glycosaminoglycans, the products of such process and pharmaceutical compositions
Inventor: PETITOU M
IPC: C08B37/08
Filed: 1986-07-14
Abstract: A glycosaminoglycane used in the form of a salt soluble in an organic medium is subjected to the action of a given sulphating agent.
Patent NZ-241702-A (NZ)
Title: Shaving unit: cap/guard formed of lubricious polymeric material
Inventor: JOHNSTON RICHARD
IPC: B26B21/44
Filed: 1992-02-24
Abstract: PCT No. PCT/GB92/00325 Sec. 371 Date Aug. 16, 1993 Sec. 102(e) Date Aug. 16, 1993 PCT Filed Feb. 24, 1992 PCT Pub. No. WO92/15430 PCT Pub. Date Sep. 17, 1992.A shaving unit (10) comprises at least one blade (13) and a blade support of moulded polymeric material which provides skin-engaging guard (11) and cap (12) surfaces, and the cap portion (12) and/or the guard portion (11) of the blade support is formed of at least one lubricious polymeric material which is more water-soluble under the conditions present during shaving than it is under other conditions, or of a mixture of such a lubricious polymeric material with one or more other materials.
Patent NZ-247549-A (NZ)
Title: Adhesive plaster for transdermal administration of estradiol (optionally with progestin) having an adhesive matrix or reservoir layer of polyacrylate or polyisobutylene
Inventor: GONELLA JACQUES
IPC: A61K9/70
Filed: 1993-05-05
Abstract: The adhesive plaster for the transdermal administration of estradiol or mixture estradiol/ progestin is composed of an impermeable carrier film and of an adhesive composition. The latter represents a matrix or reservoir layer and is composed of a solvent-based polyacrylate or polyisobutylene adhesive which contains a saturated or unsaturated fatty acid with 6 to 18 C atoms as permeability enhancer, estradiol or mixture estradiol/progestin as active substance and optionally propylene glycol as solvent. The adhesive plaster is used for the systemic administration of hormones in hormone replacement therapy for a time of at least 3 days.
Patent NZ-249792-A (NZ)
Title: Eating utensil with foldable handle arms and blade
Inventor: MACARTHUR-ONSLOW ROHAN JAMES
IPC: A47G21/00
Filed: 1993-03-16
Abstract: A foldable eating utensil includes an elongate handle member having a food-engaging blade extending integrally from one end thereof when operatively disposed, the blade being hingedly connected about a transverse axis to the inner edge of a connector plate of the handle member extending laterally between spaced handle arms of the handle member which define therebetween an opening to receive the blade to lie coplanar with the handle member when the blade is hinged to storage disposition, the blade including a longitudinally extending neck portion at its hinged connection to the connector plate and adapted to lie against the connector plate when operatively disposed, the handle arms being foldable each about a lengthwise axis adjacent the connector plate, and the parts being so made and arranged that when the blade has been hinged to operative disposition, the handle arms may be folded digitally towards each other and brought to and held in co-acting relationship in which parts of the handle member engage the blade at its neck portion in such manner as to restrain the blade against movement away from operative disposition.
Patent NZ-257955-A (NZ)
Title: Catechol diethers pharmaceutical compositions
Inventor: DUPLANTIER ALLEN J
IPC: A61K31/4439
Filed: 1993-10-29
Abstract: This invention relates to 4-substituted catechol diether compounds which are selective inhibitors of phosphodiesterase (PDE) type IV. The compounds of the present invention are useful in inhibiting PDEIV and in the treatment of AIDS, asthma, arthritis, bronchitis, chronic obstructive airways disease, psoriasis, allergic rhinitis, dermatitis and other inflammatory diseases. This invention also relates to pharmaceutical compositions comprising the compounds hereof.
Patent NZ-260510-A (NZ)
Title: Heat shrink plastics sleeve having dry film biocide for preservation of timber poles
Inventor: BAECKER ALBIN ALEXANDER WLADYS
IPC: B29C61/00
Filed: 1994-05-12
Abstract: The invention relates to synthetic plastic sheeting which is in the form of a flexible synthetic plastic film of material which has a biocide incorporated therein. The biocide can serve to inhibit the growth of different micro-organisms that cause bio-deterioration and, as such, the film can be used for packaging of or the covering, or protection of, products and objects that are exposed to bio-deterioration. The sheeting can also be provided in a sleeve form (12) permitting fitting on timber poles, for covering regions of poles to be disposed underground, in use, thereby protecting these regions against bio-deterioration.
Patent NZ-289845-A (NZ)
Title: Cascade polymer complexes and their use in diagnosis and therapy
Inventor: SCHMITT-WILLICH HERIBERT DR
IPC: A61K51/00
Filed: 1995-07-04
Abstract: Cascade polymer complexes containinga) complexing ligands of general formula I in whichA stands for a nitrogen-containing cascade nucleus of base multiplicity a,X and Y, independently of one another, stand for a direct bond or a cascade reproduction unit of reproduction multiplicity x or y,Z and W, independently of one another, stand for a cascade reproduction unit of reproduction multiplicity z or w,K stands for the radical of a complexing agent,a stands for numbers 2 to 12,x, y, z and w, independently of one another, stand for numbers 1 to 4,provided that at least two reproduction units are different and thatholds true for the product of the multiplicities,b) at least 16 ions of an element of atomic numbers 20 to 29, 39, 42, 44 or 57-83 andc) optionally cations of inorganic and/or organic bases, amino acids or amino acid amides are valuable compounds for diagnosis and therapy.
Patent NZ-293190-A (NZ)
Title: Container for ergonomic carrying with two hand grippable portions, on base/sidewall junction, and on opposing sidewall/adjacent wall junction
Inventor: JONES PETER TIMOTHY
IPC: B65D25/28
Filed: 1995-09-14
Abstract: A container of the type which can be lifted and carried by a person, the container comprising a bottom wall, a top wall, a back wall, which faces the person's body when the container is carried, a front wall opposite to the back wall, two opposed side walls extending between the back and front walls, a first hand-grippable portion positioned at the juncture between the bottom wall and one of the side walls, and a second hand-grippable portion positioned adjacent the juncture between the front wall and the other of the side walls.
Patent NZ-331512-A (NZ)
Title: Earth-based vehicle having tracks and wheel steering system
Inventor: LANSBERRY JOHN B
IPC: B62D9/00
Filed: 1997-02-05
Abstract: A vehicle (10) is provided including a main frame structure (12), a track assembly (22) mounted to the main frame structure (12) and having a single, endless ground engaging track (26) extending in a longitudinal direction.  A pair of steerable ground engaging wheels (36) flank the track (26), constructed and arranged to exert a ground bearing pressure sufficient to change a direction of travel of the track in response to turning of the wheels (36) to steer the vehicle.  Steering structure (40) is operatively associated with the wheels (36) to turn the wheels.  Power drive structure (50) is mounted with respect to the main frame structure (12) and is constructed and arranged to drive the wheels (36) and the track (26) simultaneously so as to move the vehicle along the ground.  The wheels (36) are constructed and arranged to be moved with respect to the main frame structure (12) so as to change a position thereof with respect to the main frame structure (12), thereby permitting driving, steering and ground pressure of the vehicle to be adjusted in accordance with ground conditions.
Patent NZ-332525-A (NZ)
Title: Method and apparatus for controlling electrical devices in response to sensed conditions
Inventor: ELLENBY JOHN
IPC: G06F1/32
Filed: 1997-05-21
Abstract: system (200) is disclosed that senses physical characteristics of an electronic device (214). The system (200) controls the electronic device (214) in response to the sensed physical characteristics. The system (200) includes a control subsystem. The control subsystem includes a time trigger (206) and an anticipation/latency reduction subsystem (207). The anticipation/latency reduction subsystem (207) includes additional subsystems such as a time trigger (206), a position trigger (208) and an attitude trigger (209). The various triggers can be implemented using processors that execute software. The control subsystem receives signals from the sensing devices (204, 205). Physical characteristics information obtained from these signals is provided to the various triggers (206, 208, 209, 211, 212, 213). In response to this physical characteristic information, the various triggers (206, 208, 209, 211, 212, 213) process the physical characteristic information such that the system (200) controls the electronic device (214).
Patent NZ-334031-A (NZ)
Title: Migraine treatment using substituted 1,2,3,4-tetrahydro-2-dibenzofuranamines and 2- aminocyclohepta[b]benzofurans
Inventor: FLAUGH MICHAEL EDWARD
IPC: C07D409/12
Filed: 1997-08-25
Abstract: The compounds of formula I are 5-HT1F agonists and can be used for the treatment or prevention of migraines in mammals. R1 and R2 are independently H, C1-4 alkyl, benzyl or alpha-methyl-4-nitrobenzyl; X is nitro, halo, OH, NH2, CN, NHC(O)R3, C(O)R6, NHSO2R7 or SO2NHR10; R3 is C1-6 alkyl, C2-6 alkenyl, C3-8 cycloalkyl, phenyl, napthyl, thienylmethyl or a heterocycle; R6 is hydroxy, amino, C1-6 alkoxy, benzyloxy, phenoxy or NHR8; R7 and R10 are C1-6 alkyl, phenyl or phenyl monosubstituted with halo or C1-4 alkyl; R8 is C1-6 alkyl, C2-6 alkenyl, C3-8 cycloalkyl, phenyl, naphthyl or a heterocycle; and m is 1 or 2.
Patent NZ-501462-A (NZ)
Title: Stock handling device with belt conveyor such that animal is carried lengthwise transverse to belt and is rotated during belt travel
Inventor: CATFORD IAN MURRAY
IPC: A01K1/00
Filed: 1999-12-01
Abstract: Belt 6 is located on rollers 3, 4 so that an animal (not shown) can be placed to be supported by belt 6 and rolled over as belt 6 moves.
Patent NZ-501826-A (NZ)
Title: Hinges each having two pairs of pivoted arms, one of each being adjustable, typically for display cases
Inventor: FRANK MANFRED JOHANNES
IPC: E05D3/06
Filed: 1998-08-11
Abstract: A hinge is disclosed for the mounting of a closure panel to a display cabinet. The hinge has a panel mounting member (11) to which is pivotally mounted (19) an arm (16). A second arm (12) is pivotally coupled (15) to a fixture mounting member (10). The arms (12 and 16) cross over and are joined by a pivot (20). Links (22 and 22a) which are adjustable in length are coupled between extensions (21, 21a) of the arms (12, 16) and the mounting members (10, 11) opposite to that to which the arms (12, 16) are pivotally connected.
Patent NZ-502986-A (NZ)
Title: Apparatus and method for concurrent voice and data transmission
Inventor: AMIT CHEN
IPC: H04M11/00
Filed: 1998-08-24
Abstract: Communication apparatus comprising a first xDSL transceiver for conveying an xDSL transmission, a splitter (50) for conveying a POTS transmission via a POTS telephone line and the xDSL transmission via an xDSL telephone line, and a second xDSL transceiver being in communication with the first xDSL transceiver and the splitter (50).
Patent NZ-503842-A (NZ)
Title: Radioactive and/or thermal seed implantation device
Inventor: RYDELL MARK A
IPC: A61B18/14
Filed: 1998-06-09
Abstract: Described is an instrument for implanting radioactive and/or thermal seeds in body tissue for radiation and/or heat therapy.  The instrument has a tubular hypodermic needle barrel (18) affixed to a pistol-grip shaped handle (12).  The handle incorporates a reciprocally movable push rod (26) for stripping an individual seed from a cartridge (28) and advancing it to the end of the barrel.  Actuation of the trigger in the pistol grip handle causes the barrel to retract relative to the push rod deposit  it in the channel in the body tissue created by the original puncturing effect of the instrument's barrel.
Patent NZ-504898-A (NZ)
Title: (e)-3-[1-n-butyl-5-[2-(2-carboxyphenyl)methoxy-4-chlorophenyl]-1h-pyrazol-4-yl]-2-[(5-methoxy-2,3-dihydrobenzofuran-6-yl)methyl]-prop-2-enoic acid monoargininyl salt as an endothelin receptor antagonist
Inventor: FLISAK JOSEPH ROBERT
IPC: A61P13/06
Filed: 1998-12-07
Abstract: The compound (E)-3-[1-n-Butyl-5-[2-(2-carboxyphenyl)methoxy-4-chlorophenyl]-1H-pyrazol-4-yl]-2-[(5-methoxy-2,3-dihydrobenzofuran-6-yl)methyl]-prop-2-enoic acid, monoargininyl salt.  Also described is the use of the above compound as an endothelin receptor antagonist and in the manufacture of a medicament for treating cardiovascular and renal diseases.
Patent NZ-506010-A (NZ)
Title: Apparatus for altering composition of nutritional product during enteral tube feeding
Inventor: COLE RHONDA L
IPC: A61M5/00
Filed: 1999-02-26
Abstract: An apparatus for modifying a liquid enteral nutritional product. The apparatus includes a chamber having an inlet and an outlet. The inlet of the chamber is constructed to be fluidly connected to a supply container containing a liquid enteral nutritional. The chamber defines an interior space. The apparatus further includes a retainer disposed in the interior space defined by the chamber. The retainer is constructed to receive one or more dosage form units of beneficial agent therein. The apparatus further includes at least one dosage form unit of beneficial agent retained by the retainer.
Patent NZ-511049-A (NZ)
Title: Materials and methods for the modification of plant cell wall polysaccharides
Inventor: BLOKSBERG LEONARD NATHAN
IPC: C12N15/82
Filed: 1999-10-08
Abstract: Isolated polynucleotides and polypeptides associated with the synthesis of plant cell wall polysaccharides are provided, together with genetic constructs comprising such sequences. Methods for using such constructs for the modulation of polysaccharide content in plants are also disclosed, together with transgenic plants comprising such constructs.
Patent NZ-512495-A (NZ)
Title: Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells
Inventor: ERIKSSON PETER
IPC: A61K35/12
Filed: 1999-11-25
Abstract: Use of a growth hormone or functionally equivalent analogue thereof, for the production of a medicinal product for treatment of CNS damage that effects neural stem cells, progenitor cells and or cells derived from stem cells or progenitor cells, wherein the CNS damage is caused by hypoxic, ischemic or traumatic injury, particularly neural cell loss.
Patent NZ-515308-A (NZ)
Title: Modular building system
Inventor: CROWELL JAMES H
IPC: E04B1/343
Filed: 2000-05-10
Abstract: A modular building system (100) including preformed extrusion-moulded polymeric material (116). Parts include integral connector elements (160, 162) which can be slidably and snappingly reversibly interconnected to form the basic frame (102) and panel structures (108) of an overall building. The interconnected region permits limited ranges of angular as well as translational relative motion between adjacent, connected elements. Parts are assembled simply and quickly in the field, without requiring skilled labour or specialised tools, to form a functionally solid and stable building which responds to loads and temperature changes with yieldable, accommodating deformations that minimise the likelihood of building structural damage, and effectively transmit necessary loads to the ground via load-transfer paths through the building.
Patent NZ-521165-A (NZ)
Title: Method of treating cancer with anti-neurotrophin agents
Inventor: BUCHKOVICH KAREN J
IPC: A61K48/00
Filed: 2001-02-28
Abstract: The use of at least one anti-neurotrophin antibody in the manufacture of a medicament for treating or preventing prostate or pancreatic cancer in a mammal, wherein said neurotrophin is selected from the group consisting of NGF, BDNF, NT-3, NT-4/5, NT-6 and NT-7.
Patent NZ-522984-A (NZ)
Title: Optical flow cytometry
Inventor: SHARPE JOHNATHAN
IPC: G01N21/01
Filed: 2002-12-04
Abstract: An analysation instrument including: a flow source to produce a flow of particles to be analysed; a source of electromagnetic radiation; a reflector adapted to reflect at least a portion of the electromagnetic radiation at the flow of particles to illuminate the flow of particles wherein the reflector is also adapted to collect and to reflect, to an optical configuration, at least a portion of any electromagnetic radiation produced as a result of the illumination of the flow of particles; said optical configuration including a sensor adapted to sense the electromagnetic radiation produced as a result of the illumination of the flow of particles; said optical configuration including a sensor adapted to sense the electromagnetic radiation produced as a result of the illumination of the flow of particles to derive information as to at least one characteristic of each of at least some particles in the flow; and a sorting apparatus adapted for sorting the at least some particles in the flow based on the information as to the at least one characteristic of each of the at least some particles in the flow, wherein said reflector reflects onto said flow of particles all of the electromagnetic radiation that illuminates said flow of particles. (62) Divided out of 512050
Patent NZ-525432-A (NZ)
Title: Investment casting mold and method of manufacture
Inventor: VANDERMEER JOHN
IPC: B22C1/08
Filed: 2001-11-09
Abstract: The invention relates to a investment casting molds and their  method  of  manufacture. The  method  entails  mixing refractory  fiber,  glass fiber, and  refractory  filler  to form  a  dry  blend; mixing the dry blend  with  an  aqueous colloidal  silica  sol  to  form  a  refractory  prime  coat slurry,  and employing the refractory slurry to  produce  an investment casting mold (10, 20).
Patent NZ-525502-A (NZ)
Title: Automatic door system for use with a conveyor
Inventor: RAMSEY FRANCIS JOHN
IPC: E06B3/26
Filed: 2003-04-28
Abstract: An automatic door system for operation about a conveying device, comprising at least one door assembly which is so sized and shaped to suit operation about the conveying device. Each door assembly is provided with sensors on their leading edges and is controlled to open and shut in synchronization with the operation of the conveying device and each door assembly is provided with a panel section which is pivotally connected to each respective door assembly and the panel section is biased to an orientation that is substantially coplanar with each respective door assembly. The pivotally connected panel sections are adapted to open if the door system is inadvertently shut when an article is passing on the conveying device.
Patent NZ-525861-A (NZ)
Title: An extended tethering approach for rapid identification of ligands
Inventor: ERLANSON DANIEL A
IPC: G01N33/15
Filed: 2001-11-20
Abstract: Described is a method for rapid identification and characterisation of binding partners for a target molecule, and for providing binding partners with enhanced binding affinity. More specifically, a tethering method is disclosed for the rapid identification of at least two binding partners that bind near one another to a target molecule. The figure shows a schematic illustration of the static extended tethering approach. In the first step, a target molecule containing or modified to contain a free thiol group (such as a cysteine-containing protein) is modified by a thiol-containing extender, comprising a reactive group capable of forming an irreversible covalent bond with the thiol group on the target molecule, a portion having intrinsic affinity for the target molecule, and a thiol group. The complex formed between the target molecule and the thiol-containing extender is then used to screen a library of disulfide-containing monophores to identify a library member that has the highest intrinsic binding affinity for a second binding site on the target molecule. LG = ligand ;PG = protecting group; R = reactive group.
Patent NZ-527942-A (NZ)
Title: Methods for concentrating influenza virus grown in a cell culture such that infectivity is retained
Inventor: PAU MARIA GRAZIA
IPC: A61K35/76
Filed: 2000-11-24
Abstract: Means and methods are provided for the concentration of influenza viruses whilst maintaining infectivity (at least partially), comprising obtaining a virus-containing medium, i.e. a cell cleared supernatant comprising said virus, from culture of cells, and ultrafiltrating it under low shear conditions. In particular, such low shear conditions may be obtained with a hollow fiber, and the filter is preferably designed to have a cut of at 750 KD. Such methods may include further steps that allow for the removal of proteins smaller than 750 KD. The viruses can be then be used for the production of vaccines.
Patent NZ-529258-A (NZ)
Title: Formation of small crystals
Inventor: BOWE MICHAEL JOSEPH
IPC: B01D9/02
Filed: 2002-05-02
Abstract: Small crystals are made by mixing a solution of a desired substance with an anti-solvent in a fluidic vortex mixer in which the residence time is less than 1 s, for example 10 ms. The liquid within the fluidic vortex mixer is subjected to high intensity ultrasound from a transducer in or on the wall of the mixer, or coupled to a pipe supplying liquid to the mixer. The solution very rapidly becomes supersaturated, and the ultrasound can induce a very large number of nuclei for crystal growth. Small crystals, for example less than 5 mu m, are formed that may be of a suitable size for use in inhalers.