baber/WOPTO huggingface dataset:
Patent CA-3052490-A1 (CA)
Title: Systems and methods for massively parallel combinatorial analysis of single cells
Inventor: JOHNSON DAVID SCOTT
IPC: C12N15/10
Filed: 2018-03-13
Abstract: Provided herein are methods that enable parallel evaluation of multiple functional nucleic acids in individual cells or subpopulations of cells, in the context of incubation with other types of single cells. The key insight is concurrent measurement of polynucleic acids derived from small populations of at least two different cell types, such that function in one cell type is linked to the clonal identity of another cell. These methods simultaneously process thousands, millions, or more single cells or small populations of cells. The method integrates molecular, algorithmic, and engineering approaches. This invention has broad and useful application in a number of biological and medical fields, including immunology and drug discovery.
Patent CA-3053671-A1 (CA)
Title: Outil separable servant a effectuer un couplage a l'interieur d'un puits de forage
Inventor: SAPONJA JEFFREY CHARLES
IPC: E21B17/02
Filed: 2018-03-15
Abstract: L'invention concerne un dispositif de raccord comprenant des première et deuxième parties homologues de dispositif. Les première et deuxième parties homologues de dispositif sont configurées coopérativement de sorte que : un couplage séparable entre la première et la deuxième partie de dispositif puisse être effectué, tandis que la première partie de dispositif est couplée amovible à la deuxième partie de dispositif dans une position de couplage amovible : (i) le déplacement de la première partie de dispositif par rapport à la deuxième partie de dispositif le long d'un axe dans une première direction étant empêché ou sensiblement empêché; et (ii) la première partie de dispositif pouvant être déplacée par rapport à la deuxième partie de dispositif le long d'un axe dans une deuxième direction opposée ou sensiblement opposée à la première direction, pour effectuer la séparation de la première partie de dispositif du couplage avec la deuxième partie de dispositif, la première partie se retrouvant ainsi en position séparée. La séparation de la première partie de dispositif du couplage amovible à la deuxième partie de dispositif peut être effectuée en l'absence ou en l'absence substantielle d'un couple appliqué sur la première partie de dispositif autour d'un axe parallèle ou sensiblement parallèle à l'axe longitudinal central de la première partie de dispositif.
Patent CA-3055645-A1 (CA)
Title: Systeme de paiement base sur un serveur de gestion de fonds partages, et procede, dispositif et serveur correspondants
Inventor: ZHANG YI
IPC: G06Q20/38
Filed: 2015-05-28
Abstract: Un système de paiement basé sur un serveur de gestion de fonds partagé, ainsi quune méthode, un dispositif et un serveur connexes sont décrits, lesquels ont trait au domaine du commerce électronique. La méthode comprend les étapes suivantes : un serveur de gestion de fonds reçoit des renseignements concernant une demande de paiement envoyée par un client; la somme dun solde de fonds et dune limite de prêt de crédit du client est comparée au montant dun paiement, et lon détermine si un certificat dengagement de paiement électronique peut être ouvert; le cas échéant, le serveur de gestion de fonds gèle respectivement le solde de fonds et la limite de prêt de crédit, qui correspondent au montant du paiement, dans un compte client; le certificat dengagement de paiement électronique est généré pour que le serveur de gestion de fonds accepte de payer les fonds en fonction dune condition convenue et le certificat dengagement de paiement électronique est envoyé à un commerçant afin deffectuer un paiement de crédit au nom du client, puis synchronisé avec un serveur de centre dinformation. Le fait dutiliser la solution technique de la présente invention pour superviser les deux parties à une transaction permet de réduire le risque financier et de garantir les intérêts des deux parties à la transaction.
Patent CA-3061217-A1 (CA)
Inventor: LEACH CONNOR FRANCIS
IPC: A61K36/06
Filed: 2019-11-10
Abstract: The present disclosure described is a fill formulation method for hard, soft, and liquid capsules comprising a polymer and a fill component, wherein the polymer comprised of mycoprotein is mixed with a fill component mixture comprised of a plasticizing agent, a preservative agent, a lubricant agent, and purified water, which will migrate into or through a capsule shell, with attributes of serviceable functions.
Patent CA-3062282-A1 (CA)
Title: Systems and methods for supporting multiple allocations in ul/dl grant for a 5g nr ue and gnb
Inventor: SHAHEEN KAMEL M
IPC: H04L5/00
Filed: 2018-05-01
Abstract: A user equipment (UE) is described. The UE includes a receiving circuitry configured to receive a radio resource control message including first information used for determining a monitoring occasion where the UE monitors a physical downlink control channel (PDCCH) in a search space. The receiving circuitry is also configured to receive a radio resource control message including second information used for determining downlink control information (DCI) formats which accordingly the UE monitors the PDCCH in the search space. The search space is a UE-specific search space. The monitoring occasion comprises a slot and/or a symbol. The DCI formats include a DCI format used for scheduling of a physical uplink shared channel (PUSCH) and/or a DCI format used for scheduling of a physical downlink shared channel (PDSCH).
Patent CA-3062506-A1 (CA)
Inventor: TERRETT JONATHAN ALEXANDER
IPC: C12N15/60
Filed: 2018-05-11
Abstract: L'invention concerne des matériaux et des procédés de production de cellules d'édition génomique modifiées pour exprimer une construction de récepteur d'antigène chimérique (CAR) sur la surface cellulaire, ainsi que des matériaux et des procédés d'édition génomique pour moduler l'expression, la fonction ou l'activité d'un ou de plusieurs gènes associés à l'immuno-oncologie dans une cellule, et des matériaux et des procédés de traitement d'un patient à l'aide des cellules modifiées d'édition génomique.
Patent CA-3064082-A1 (CA)
Title: Vacuum breaker with back flow preventer
Inventor: LEI MARTIN
IPC: F16K24/00
Filed: 2019-12-05
Abstract: A dual purpose valve assembly may comprise a conduit, a first valve, and a second valve. The first valve may comprise a vacuum breaker valve. The second valve may comprise a check valve. A drain system may comprise a supply tube, a drain tube, and a dual purpose valve disposed between the supply tube and the drain tube. The drain system may allow fluid to drain based on gravity alone, and the dual purpose valve assembly may operate based on gravity alone.
Patent CA-3064411-A1 (CA)
Title: Wand with boost and mode selections
Inventor: MACSAY STEVEN M
IPC: E03C1/04
Filed: 2019-12-10
Abstract: A wand with boost and mode selections having a high flow capacity and a compact size is provided. The wand comprises a shell, a waterway, and a face module. The waterway includes boost and mode modules. The boost module includes fixed and movable boost sub-modules. The mode module includes fixed and movable mode sub-modules. The movable boost sub-module and the movable mode sub-module are operable to move in a generally longitudinal and circumferential direction, respectively. A first flow passage of the fixed boost sub-module, a second flow passage of the movable boost sub-module, a third flow passage and flow openings of the movable mode sub-module, and first and second outlet passages of the fixed mode sub-module extend in and a flow of water therethrough extends in a generally longitudinal direction. A ratio of a flow coefficient of the wand to a volume of the shell is greater than approximately 0.125.
Patent CA-3064874-A1 (CA)
Inventor: BLASICK FRANCIS JOHN
IPC: H01R13/17
Filed: 2019-12-12
Abstract: A coaxial connector assembly includes a connector module having a connector body that includes contact cavities extending between a front side and a rear side of the connector body. The connector module has a cover having openings. Coaxial contacts are received in corresponding contact cavities each having a coaxial signal element and outer contact. The outer contact has a cable segment coupled to a coaxial cable and a mating segment. The cable segment has a front section and a rear section having a larger diameter than the front section and located rearward of the cover to receive the cable. The front section passes through the opening into the contact cavity to engage the mating segment. Biasing springs are located between the cover and the mating segment of the coaxial contact to bias the coaxial contact in the mating direction.
Patent CA-3067559-A1 (CA)
Title: Device and method for continuous analysis of the concentration of dissolved inorganic carbon (dic) and of the isotopic carbon and oxygen compositions thereof
Inventor: SANS-JOFRE PIERRE
IPC: G01N21/39
Filed: 2018-07-09
Abstract: The present invention relates to a novel analysis device and method for obtaining the concentration of dissolved inorganic carbon (DIC) and isotopic carbon and oxygen concentration thereof, continuously from a liquid sample.
Patent CA-3069764-A1 (CA)
Title: Electrochemical strips for monitoring the degradation of body fat and method for preparing same
Inventor: DELILE SEBASTIEN
IPC: G01N27/327
Filed: 2018-07-13
Abstract: The present invention relates to the field of personalized monitoring of changes in metabolism as a function of external parameters such as food or physical exercise. More particularly, the invention relates to electrochemical strips for detecting the amount of a biomarker for fat metabolism, in particular glycerol.
Patent CA-3070323-A1 (CA)
Title: Traitement additif de fluoropolymeres
Inventor: NELSON PER MILES
IPC: C08J9/24
Filed: 2018-07-18
Abstract: L'invention concerne des procédés de fabrication de fluoropolymère mis en forme par traitement additif à l'aide de particules de fluoropolymère, d'un liant polymérisable et d'une extraction avec des fluides supercritiques. L'invention concerne également des compositions pour l'impression en 3D permettant de fabriquer des articles à base de fluoropolymère mis en forme et des articles comprenant un fluoropolymère mis en forme.
Patent CA-3071016-A1 (CA)
Inventor: PTACIN JEROD
IPC: C07K14/55
Filed: 2018-08-03
Abstract: Disclosed herein are interleukin (IL) conjugates (e.g., IL-2 conjugates) and use in the treatment of one or more indications.  Also described herein are pharmaceutical compositions and kits comprising one or more of the interleukin conjugates (e.g., IL-2 conjugates).
Patent CA-3071185-A1 (CA)
Title: Method for preparation of heterogeneous catalysts
Inventor: SUSSMAN VICTOR J
IPC: C07C69/54
Filed: 2018-06-25
Abstract: A method for preparing a heterogeneous catalyst. The method comprises steps of: (a) combining (i) a support, (ii) an aqueous solution of a noble metal compound and (iii) a C2-C18 thiol comprising at least one hydroxyl or carboxylic acid substituent; to form a wet particle and (b) removing water from the wet particle by drying followed by calcination to produce the catalyst.
Patent CA-3073996-A1 (CA)
Title: Polytherapie de lasmiditan et d'un antagoniste du cgrp pour une utilisation dans le traitement de la migraine
Inventor: AURORA SHEENA
IPC: A61K31/4545
Filed: 2018-08-30
Abstract: La présente invention concerne des combinaisons de lasmiditan et d'un antagoniste du peptide lié au gène de la calcitonine (CGRP), par exemple la combinaison de lasmiditan et de galcanezumab, et des méthodes d'utilisation des combinaisons pour le traitement de la migraine, particulièrement, pour traiter la migraine mal contrôlée par lasmiditan ou une thérapie par antagoniste du CGRP, et plus particulièrement pour traiter une migraine résistante à la thérapie qui est définie dans la description en tant que migraine réfractaire à au moins deux schémas thérapeutiques précédents en monothérapie et/ou double thérapie.
Patent CA-3074401-A1 (CA)
Inventor: Ohlmann Dominik
IPC: C07H1/00
Filed: 2018-09-28
Abstract: The presently claimed invention is directed to a process for preparing D-glucaro-6,3-lactone monoamide from D-glu-caro-6,3 -lactone.
Patent CA-3076335-A1 (CA)
Inventor: TUNES KENNETH
IPC: E21B34/10
Filed: 2018-10-25
Abstract: A well tool device (1) comprising a housing (10) having a through channel (11) with a first end (11a) and a second end (11b), said housing (10) further comprises a breakable ball seat (15), wherein a drop ball (17) received in the ball seat (15) 5 partially or fully closes fluid communication in the through channel (11) of the housing (10). The breakable ball seat (15) is made of brittle and/or tempered glass, wherein the ball seat (15) is broken by a pressure build up in the housing (10) forcing the ball seat (15) against one or more disintegrating means (16), said disintegrating means (16) are provided as inside protrusions in the through channel (11).
Patent CA-3077120-A1 (CA)
Title: Spreadable fat-containing food products
Inventor: VERBEECK SABRINA
IPC: A23G3/40
Filed: 2018-09-28
Abstract: An edible product suitable for use as spreads comprising, based on the total weight of the edible product, from 15 to 80 percentage by weight (wt %) of a glyceride composition, from 20 to 85 wt % of a fat free part comprised in at least one filler material, and at most 20 wt % of water, wherein the glyceride composition comprises, with respect to the total weight of the glyceride composition, from 5 to 20 wt % of saturated fatty acid residues (SAFA), at most 3 wt % of trans unsaturated fatty acid residues (TFA), at most 8 wt % of C12:0 fatty acid residues, C14:0, C16:0 and C18:0 fatty acid residues wherein the weight ratio of (C14:0 + C16:0) / C18:0 is at most 1.0, SUS- triglycerides and SSU-triglycerides wherein the weight ratio of SUS/SSU is more than 1.0, wherein S represents a saturated fatty acid residue having from 16 to 18 carbon atoms and U represents an unsaturated fatty acid residue having 18 or more carbon atoms, and wherein the composition (GF) has a solid fat content (SFC) at 20°C of less than 5 wt % and a SFC at 35°C of less than 1 wt % wherein the SFC is measured according to International Union of Pure and Applied Chemistry (IUPAC) method 2.150 a, and wherein the edible product has a hardness (T) of maximum 1000 g and a ratio ( R ) between the hardness (T) and the SFC at 20°C, R = T/SFC20 of at least 125.
Patent CA-3077430-A1 (CA)
Inventor: VOISIN PAUL ALBERT
IPC: B64D45/00
Filed: 2018-10-03
Abstract: Various display systems may benefit from the combination of synthetic imagery from a plurality of sources. For example, display systems for vehicular operations may benefit from combining synthetic imagery with real imagery. A method can include obtaining, by a processor, an interior video image based on a position of a user. The method can also include obtaining, by the processor, an exterior video image based on the position of the user. The method can further include combining the interior video image and the exterior video image to form a combined single view for the user. The method can additionally include providing the combined single view to a display of the user.
Patent CA-3078212-A1 (CA)
Inventor: RIVERIN GUY
IPC: B64D31/00
Filed: 2020-04-15
Abstract: Method and system for controlling engine speed in a multi-engine aircraft, comprising monitoring a request for a first engine and a second engine to generate a given thrust and determining a corresponding engine speed for the first engine and the second engine in accordance with the given thrust. When the corresponding engine speed is outside of a selected speed range, a first engine speed and a second engine speed are allowed to track the corresponding engine speed. When the corresponding engine speed is within the selected speed range, a transition of the first engine speed and the second engine speed through the selected speed range is staggered by allowing one of the first engine speed and the second engine speed to transition through the selected speed range while holding the other of the first engine speed and the second engine speed outside of the selected speed range.
Patent CA-3078482-A1 (CA)
Title: Managing a computing cluster based on consistency of state updates
Inventor: STANFILL CRAIG W
IPC: G06F9/52
Filed: 2018-10-30
Abstract: A method for processing state update requests in a distributed data processing system includes processing a set of state update requests associated with a first time interval including maintaining a count of issued state update requests for the set of state update requests, maintaining a count of state updates performed for the first set of state update requests, and updating a state consistency indicator to indicate that state updates associated with all state update requests of the first set of state update requests have been performed in response to determining that the count of state updates performed for the first set of state update requests equals the count of issued state update requests for the first set of state update requests.
Patent CA-3081237-A1 (CA)
Title: System and process for teaching speech to people with hearing and/or speech disabilities
Inventor: KAUL SANDRA
IPC: G09B1/32
Filed: 2020-05-22
Abstract: Systems and processes to teach speech utilizing visual phonemes as physical representations or surrogates of spoken sounds, wherein the visual phonemes also include the letters and letter combinations that are used in a way that sounds the phoneme when spoken and words corresponding to the letter of letter combinations that use the letter or letter combinations therein in a way that sounds the phoneme when spoken.
Patent CA-3081251-A1 (CA)
Inventor: AMAYEH GHOLAMREZA
IPC: G06T7/70
Filed: 2012-05-19
Abstract: A system is provided for identifying reference locations within the environment of a device wearer. The system includes a scene camera mounted on eyewear or headwear coupled to a processing unit. The system may recognize objects with known geometries that occur naturally within the wearer's environment or objects that have been intentionally placed at known locations within the wearer's environment. One or more light sources may be mounted on the headwear that illuminate reflective surfaces at selected times and wavelengths to help identify scene reference locations and glints projected from known locations onto the surface of the eye. The processing unit may control light sources to adjust illumination levels in order to help identify reference locations within the environment and corresponding glints on the surface of the eye. Objects may be identified substantially continuously within video images from scene cameras to provide a continuous data stream of reference locations.
Patent CA-3082582-A1 (CA)
Title: Pilote et commande de charge a impedance variable
Inventor: LIPKENS BART
IPC: B01D17/00
Filed: 2018-06-13
Abstract: L'invention concerne une onde stationnaire acoustique utilisée pour séparer des composants d'un fluide à composants multiples, tel que l'huile d'un mélange huile-eau, ou des cellules entraînées dans un fluide, dans un schéma d'écoulement de fluide à l'aide d'un dispositif d'acoustophorèse. Par exemple, le schéma d'écoulement et le dispositif permettent le piégeage de l'huile lorsque l'huile fusionne, s'agglomère et devient plus flottante que l'eau. Un pilote et un dispositif de commande du dispositif acoustophorétique reçoivent une charge variable lorsque les composants sont séparés, ce qui permet d'améliorer l'efficacité de séparation.
Patent CA-3083648-A1 (CA)
Title: Preparation of a fuel blend
Inventor: NORTIO JENNI
IPC: C10G3/00
Filed: 2018-11-22
Abstract: A method is disclosed for preparing a renewable fuel blend. The method comprises subjecting at least two feedstocks of different biological origins to catalytic cracking in a catalytic cracking unit and to hydrotreatment in a hydrotreatment unit to form a fuel blend having an aromatic hydrocarbon content from 26 to 42 wt-% and a paraffinic hydrocarbon content of less than 53 wt-%, as measured according to ASTM D2425-04 (2011). The fuel blend is formed by mixing the at least two feedstocks together before subjecting them to the catalytic cracking and hydrotreatment, or by obtaining a first fuel component and at least one further fuel component from the catalytic cracking and hydrotreatment of the at least two feedstocks, and mixing said first fuel component and said at least one further fuel component together.
Patent CA-3087681-A1 (CA)
Inventor: BRAUN ALEXANDER L
IPC: H03K19/195
Filed: 2019-01-25
Abstract: La présente invention concerne un circuit de porte à logique quantique inverse (RQL) qui possède un étage d'entrée comprenant des entrées logiques affirmées en fonction de la réception d'impulsions positives quantiques à flux unique (SFQ) et un étage de sortie d'amplification comprenant une JTL de manière à délivrer un signal de sortie. L'étage d'entrée comprend deux boucles de stockage ou plus, au moins deux boucles desdites boucles étant chacune associée à une entrée logique, comprenant chacune une jonction Josephson (JSET) d'entrée, une inductance de stockage et une JSET de décision logique, la JSET de décision logique étant commune à toutes les boucles de stockage associées aux entrées logiques et étant configurée pour se déclencher en fonction d'une polarisation fournie par un ou plusieurs courants stockés dans les boucles de stockage et d'un signal de polarisation appliqué au circuit. L'étage de sortie affirme une sortie en fonction du déclenchement de la JSET de décision logique.
Patent CA-3088661-A1 (CA)
Title: Methodes de traitement du diabete, de l'hepatite et/ou d'une maladie hepatique inflammatoire
Inventor: LYNES MICHAEL A
IPC: A61K47/66
Filed: 2019-01-17
Abstract: L'invention concerne des utilisations d'un inhibiteur de la métallothionéine (MT) humaine extracellulaire pour traiter un trouble choisi dans le groupe constitué par le diabète, le pré-diabète, la tolérance au glucose altérée, l'hépatite, et/ou la maladie hépatique inflammatoire, et des compositions contenant la MT humain extracellulaire.
Patent CA-3089569-A1 (CA)
Title: Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
Inventor: SHAILUBHAI KUNWAR
IPC: A61K38/17
Filed: 2008-06-04
Abstract: The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cGMP- dependent phosphodiesterase. The gastrointestinal disorder may be classified as either irritable bowel syndrome, constipation, or excessive acidity etc. The gastrointestinal disease may be classified as either inflammatory bowel disease or other GI condition, including Crohn's disease and ulcerative colitis, and cancer.
Patent CA-3090373-A1 (CA)
Title: Procede d'administration d'un medicament a un muscle
Inventor: TAKAHASHI KENICHI
IPC: C12N15/56
Filed: 2019-02-05
Abstract: Le problème décrit par la présente invention est de fournir un procédé permettant d'incorporer de manière efficace un médicament qui doit fonctionner dans un tissu musculaire, mais lorsqu'il est administré à un organisme, il n'est lui-même pas incorporé de manière adéquate dans un tissu musculaire, en particulier dans un tissu musculaire constitué d'un muscle squelettique ou d'un muscle cardiaque. La solution selon l'invention porte sur un complexe d'un médicament et d'un anticorps anti-récepteur de la transferrine humain, le médicament étant un médicament ayant une activité physiologique qui doit présenter une fonctionnalité dans un tissu musculaire, par exemple, une enzyme lysosomale telle qu'une a-glucosidase acide ou une alpha-galactosidase A.