baber/WOPTO huggingface dataset:
Patent BR-112023001739-A2 (BR)
Title: Anticorpo específico para mucina-1 e métodos de uso do mesmo
Inventor: DAVID RABUKA
IPC: A61K39/00
Filed: 2021-07-30
Abstract: ANTICORPO ESPECÍFICO PARA MUCINA-1 E MÉTODOS DE USO DO MESMO A presente descrição provê anticorpos específicos para Mucina 1. Os ácidos nucleicos que codificam uma ou ambas as cadeias variáveis de um anticorpo da presente descrição também são providos, assim como as células que incluem tais ácidos nucleicos. Também são providas composições que incluem os anticorpos da presente descrição, incluindo, em alguns casos, composições farmacêuticas. Também são providos métodos de produção e uso dos anticorpos da presente descrição. Em certos aspectos, são providos métodos que incluem a administração a um indivíduo com um distúrbio proliferativo celular de uma quantidade terapeuticamente eficaz de um anticorpo da presente descrição, em que o anticorpo é administrado ao indivíduo para intensificar uma resposta imune, por exemplo, uma resposta de células T, à proliferação anormal de células do distúrbio proliferativo celular. Os anticorpos também são úteis em várias aplicações de diagnóstico e monitoramento, que também são providas.
Patent BR-112023012422-A2 (BR)
Title: Inibidores da atp sintase - usos cosmético e terapêutico
Inventor: MICHAEL DAVD FORREST
IPC: A61K38/00
Filed: 2021-01-24
Abstract: inibidores da atp sintase-usos cosmético e terapêutico setor técnico = farmacêutica / biotecnologia / cosméticos. com dados experimentais de suporte, esta divulgação ensina que a atividade da proteína if1 é um determinante molecular do tempo de vida, explicando por que diferentes espécies têm diferentes tempos de vida máximos e ensina uma proteína/fragmento if1 (ou variante de sequência do mesmo), ou uma proteína de fusão do mesmo, opcionalmente uma proteína de fusão compreendendo uma sequência de peptídeo de penetração celular (cpp), como um agente para retardar/retardar/reduzir o envelhecimento em um sujeito, opcionalmente como um componente de um cosmético, opcionalmente para tratar uma doença/distúrbio correlacionado com a idade. além disso, ensina outros inibidores da hidrólise de f1f0 atp, incluindo pequenas moléculas, de vários scaffolds diferentes, para esta finalidade. além disso, com suporte de dados experimentais, ensina quecompostos que retardamo modo de hidrólise de atp da sintase de atp são úteis para o tratamento de várias doenças e distúrbios, incluindo câncer, particularmente cânceres que utilizam o efeito warburg.
Patent BR-112023014338-A2 (BR)
Title: Método e aparelho de determinação de temporização de transmissão
Inventor: LIU FENGWEI
IPC: H04W56/00
Filed: 2021-01-15
Abstract: método e aparelho de determinação de temporização de transmissão. um método e aparelho de determinação de temporização de transmissão são fornecidos para determinar uma temporização de transmissão de um nó de iab. o método é aplicado a um primeiro nó, e um segundo nó pode ser um nó de nível superior ou um nó doador do primeiro nó. o método inclui: o primeiro nó recebe informação de controle a partir do segundo nó, onde a informação de controle inclui informações de agendamento de transmissão de enlace ascendente, e a informação de controle inclui primeira informação de embaralhamento. o primeiro nó determina um primeiro tipo de temporização associado à primeira informação de embaralhamento. o primeiro nó determina uma temporização de transmissão da transmissão de enlace ascendente com base no primeiro tipo de temporização.
Patent BR-112023015472-A2 (BR)
Title: Métodos para fazer formas transisoméricas de moduladores de receptores acoplados à proteína g
Inventor: Younai Ashkaan
IPC: C07D401/14
Filed: 2022-01-28
Abstract: métodos para fazer formas transisoméricas de moduladores de receptores acoplados à proteína g. são divulgados no presente documento, entre outros, métodos de síntese de formas isoméricas trans de moduladores de receptores acoplados à proteína g de pureza transisomérica alta.
Patent BR-112023018672-A2 (BR)
Title: Sal de ácido orgânico, composição e uso
Inventor: YOON DASEUL
IPC: C07D471/04
Filed: 2022-03-16
Abstract: sal de ácido orgânico, composição e uso. a presente invenção se refere a sais inéditos de um composto heterocíclico como um inibidor de proteína quinase e ao uso dos mesmos. os sais inéditos são soberbos em termos de solubilidade em água e estabilidade física e química e, assim, podem ser empregados de forma útil na formulação de produtos medicinais. além do mais, o composto heterocíclico ou os sais do mesmo podem efetivamente tratar e impedir dermatite atópica e doença do intestino inflamatório.
Patent BR-112023020567-A2 (BR)
Title: Guia de ondas óptico , sistema de guia de ondas óptico, estrut uras confinantes de luz, estrutura de armazenamento de energia luminosa, sistema de armazenamento de energia luminosa e sistema de armazenamento e/ou conversão de energia
Inventor: ALUIZIO M CRUZ
IPC: H01L31/055
Filed: 2022-04-05
Abstract: guia de ondas óptico, sistema de guia de ondas óptico, estruturas de confinamento de luz, estrutura de armazenamento de energia da luz, sistema de armazenamento de energia da luz e sistema de armazenamento e/ou conversão de energia. a presente invenção refere-se a guia de ondas óptico, sistema de guia de ondas óptico com guia de ondas óptico, estrutura de armazenamento de energia luminosa, estruturas confinantes de luz, sistema de armazenamento de energia luminosa e de armazenamento e/ou conversão de energia com sistema de guia de onda ótico. guia de ondas óptico é provido, compreendendo fibra óptica com núcleo de fibra e estrutura de revestimento ativo óptico através de porção do núcleo de fibra em primeira extremidade do guia de ondas óptico, em que estrutura de revestimento ativo óptico compreende empilhamento de espelho de bragg tendo alta transmitância em primeira região de comprimento de onda e alta refletividade em segunda região de comprimento de onda de comprimentos de onda mais longos do que na primeira região e revestimento de conversão de comprimento de onda sobre núcleo de fibra da fibra ótica. o revestimento de conversão de comprimento de onda é configurado para converter radiação com comprimentos de onda na primeira região de comprimento de onda em radiação com comprimentos de onda na segunda região de comprimento de onda e empilhamento de espelho de bragg é disposto sobre revestimento de conversão de comprimento de onda.
Patent BR-112023020885-A2 (BR)
Title: Sistema de medição de consumo de produto e dispositivo de medição de consumo de produto
Inventor: WILLIAM VON DRASEK
IPC: C02F1/00
Filed: 2022-04-07
Abstract: sistema de medição de consumo de produto e dispositivo de medição de consumo de produto. um dispositivo de monitoramento de consumo de produtos químicos usando sensores de força integrados em um alojamento de sensor selado para instalação de adaptação em sistemas de alimentação de produtos químicos líquidos ou sólidos usados no tratamento de água. a concepção do sensor é flexível e pode ser usado com produtos com diferentes formatos, tais como discos, frascos, grânulos ou baldes. o sensor é utilizado para monitorar a taxa de consumo do produto com base no peso ou porcentagem para gerenciamento de estoque, prevendo a programação de reabastecimento e fornecendo um processo para pedidos automáticos. ao combinar a medição do consumo do produto com outros dados do sensor do dispensador, sistema de distribuição de produtos químicos ou processo, permite rastrear o desempenho do dispensador e emitir alarmes em caso de defeito. adicionalmente, o uso de dados de diferentes fontes fornece visibilidade remota para agendamento de manutenção e solução de problemas.
Patent SK-1996-A3 (SK)
Title: Pharmaceutical composition for solubilisation of hardly soluble active substance in the carrier and preparation method thereof
Inventor: POSANSKI ULRICH
IPC: A61K47/14
Filed: 1994-07-08
Abstract: Pharmaceutical prepn. comprises () a pharmaceutically active agent which is sparingly soluble in water; and (b) a carrier compsn. comprising (i) at least one polyglycerine fatty acid ester and/or at least one sorbitan fatty acid ester, (ii) at least 1 conventional pharmaceutical oil contg. a triglyceride as lipophilic component and (iii) at least 1 nonionic surfactant with a HLB value of at least 10.   The active agent is pref. a cyclosporin, rapamycin, tacrolimus, deoxyspergualine, nifedipine, nimodipine, etoposide, ibuprofen or alpha-lipoic acid. The active agent has a solubility, in distilled water, of less than 500mg/1000ml. The active agent concn. is 1-30 wt.%, based on the carrier compsn. The carrier compsn. comprises 10-50 wt.% component (i), 5-40 wt% component (ii) and 10-50 wt % component (iii).
Patent CZ-9900258-A3 (CZ)
Title: Catching device, particularly for lifting gear with rack drive
Inventor: KOUPENY JAROSLAV ING
IPC: B66B5/18
Filed: 1999-01-26
Abstract: The invented device is formed by a box (1) intended for attaching to an elevator platform or cage that is provided on inner side with a conical friction surface being in engagement with an outer conical surface of a drum (5) due to force of a spring (12) bearing at its one end against the box (1) and at the other end against a nut (13) screwed on the drum (5) shaft (6). The drum (5) is mounted together with the shaft (6) rotatably with possibility to be entrained by a centrifugal pawl (9) on a coaxial shaft (2) of a toothed wheel (3) protruding from the box (1) and intended for engagement with the elevator toothed rack. The drum (5) is forced off in its stand-by rest position from engagement with the box (1) conical surface through the mediation of a forcing-off device that bears against the nut (13) and that is formed by a screw (17) screwed in the box (1) cover (16) co-axially with the drum shaft (6) and a packing piece (18) being rotatably secured on the screw (17) and being provided on its pin with a circular ring.
Patent CZ-75194-A3 (CZ)
Title: Stabilized composition and process for preparing thereof
Inventor: HESP SIMON
IPC: C08L47/00
Filed: 1992-09-30
Abstract: Insoluble particulate materials, which may be in solid or liquid form, are dispersed in a continuous non-aqueous phase and the dispersion rendered stable and resistant to phase separation by an in-situ stabilization procedure involving the formation of chemical bonds among the stabilizer components and to dispersed phases to form a network surrounding the particles which is compatible with the continuous phase. The invention has particular application for the formation of stabilized polyolefin-modified bitumen compositions for paving and other applications.
Patent CZ-90894-A3 (CZ)
Inventor: STARZ JOSEF
IPC: E03F5/02
Filed: 1994-04-15
Abstract: Zařízení má ve vsuvné části (2), opatřené vnitřním závitem
(5), našroubován kryt (1) s vnějším závitem (4). Vsuvná
část (2) je dělená a opatřená aretačními šrouby.
Patent CZ-99993-A3 (CZ)
Title: Double separator for particulate material sorting
Inventor: FOLSBERG JAN
IPC: B07B7/083
Filed: 1991-11-13
Abstract: A double separator for sorting particulate material, e.g. raw materials of cement or cement clinker comminuted in a roller press, and in which the material charge is suspended in a conveying gas, and consisting of a coarse separator (2), on top of which a fine separator (1) is mounted directly. The coarse separator (2) has a material inlet duct (15), a centrifugal pulverizer or rotor with arms (16) forming a desagglomerator, a gas inlet duct (18) and a material outlet duct (21) for a separated coarse fraction. The fine separator (1) has a material gas inlet duct (9), an additional material inlet duct (11), an outlet duct (3) for a fine fraction in suspension and an outlet duct (10) for a separated coarser fraction.
Patent SK-59495-A3 (SK)
Title: Method and device for manufacturing cement clinker
Inventor: YOUNG ROM D
IPC: C04B7/147
Filed: 1995-05-09
Abstract: To charge loaded to the charging end (16) of the cement rotary furnace (12) steel slag is added. Steel slag is grinded and situated so that the maximal diameter of its pieces is 5 cm. Raw materials and slag move in direction to the hot end (18) of the rotary furnace (12). The slag melts consequently to the increased temperature and diffuses to the said charge of the raw material producing cement clinkers. Cement rotary furnace (12) has a charging end (16) and a hot end (18), which is declined down opposite to the charging end (16). Loading of the charge of the raw materials and steel slag is secured by conveyers (24) and (46), the speed of which is controlled by controlling device (25).
Patent SK-59795-A3 (SK)
Title: 5,6-dihydro-4h-thieno £3,4-c| pyrole derivatives, method of their preparation and pharmaceutical agents contained these derivatives
Inventor: BEDOYA ZURITA M
IPC: A61P25/02
Filed: 1995-05-09
Abstract: 5,6-dihydro-4H-thienoÄ3,4-cÜpyrrole derivs. of formula (I) and their acid addn. salts are new. R1 = cyano, 1-4C alkoxy, alkylthio or alkylsulphonyl, pyridyl, 3,4-dimethoxyphenyl or cyclopropyl (opt. substd. by one or two alkyl) or COR or benzyl (substd. by one or more halo and/or 1-4C alkyl or alkoxy or CO2R') or naphthylmethyl; R = 1-4C alkyl, phenyl or piperidinyl; R' = 1-4C alkyl.
Patent SK-72006-A3 (SK)
Inventor: MICHLO JAROSLAV
IPC: C08J3/00
Filed: 2006-01-16
Abstract: Opísaná je modifikovaná drvina na báze odpadového ľahčeného
polystyrénu, ktorá pozostáva z ľahčeného polystyrénu
vo forme drviny s distribúciou hlavnej frakcie v rozmedzí
1 až 10 mm a modifikačných činidiel na báze esterov
vyšších mastných kyselín s glycerínom v množstve 0,1 až
0,5 % hmotn. vzhľadom na množstvo použitej drviny.
Patent CZ-237891-A3 (CZ)
Title: method of enhancing heat transfer in a furnace and a coating composition for carrying-out the same
Inventor: SMRCEK JOSEF ING CSC
IPC: C03B5/05
Filed: 1991-07-30
Abstract: To improve the transfer of heat in a heating or melting furnace from the burner or electric heating element to the heated or melted material inside the furnace, the heat exchange surface is covered with at least one layer of a suspension of at least one substance from the group which includes iron trioxide, chromic oxide, nickelous oxide, cobalt dioxide, manganese dioxide, uranium oxide, and oxides and/or orthosilicates of metals from the group which includes zirconium, titanium, magnesium, aluminium, tin and lead, in a 10 to 40% aqueous colloidal solution of silicon dioxide, this layer is dried and then burned at a temperature of 1,000 to 1,400 degrees C into a smooth glassy enamel. The graininess of the metal oxides and/or silicates is preferably 0.5 to 10 micrometers or 10 to 100 micrometers.
Patent CZ-160699-A3 (CZ)
Inventor: MULLER PASCALE FRANCINE JEANNE
IPC: C08L9/04
Filed: 1999-05-05
Abstract: Způsob syntézy latexu karboxylované nitrilové pryže spočívá v
tom, že se 1/ zahájí terpolyrrerace 1,3-butadienu, akiylonitrilu a
kyseliny metakrylové ve vodnémprostředí přidánímpersíranu
draselného a iniciátoru persíranu draselného, přičemž
terpolyrrerace se zahajuje v reaktoru, naplněnémnejméně na 60
%, 2/ terpolyrrerace se nechá probíhat při teplotě v rozmezí 25 až
80 °C až do vytvoření obsahu pevného podílu nejméně 20 % k
získání polymemího latexujako očkovacího materiálu, 3/ přidá se
další 1,3-butadien, akrylonitril a persíran draselný k očkovacímu
polymemímu latexu v průběhu nejménějedné hodiny za vzniku
druhého polymemího prostředí, načež se 4/ nechá polymerace dále
probíhat ve druhémpolymeračnímprostředí nejméně půl hodiny
za vzniku latexu karboxylované nitrilové pryže. Součást řešení
tvoří rovněž takto získaný latex ajeho použití.
Patent CZ-175193-A3 (CZ)
Title: Mobile biofermenter
Inventor: JIRKOVSKY VACLAV
IPC: A01C3/02
Filed: 1993-08-25
Abstract: The mobile biofermenter consists of a thermal insulating jacket (1) and is equipped with a device for input and output of air. The thermal insulating jacket (1), forming sides, ceiling and door (2) of the mobile biofermenter, consisting of formed plates (3), whose surface is equipped with a set of ribs (4) on which the thermal insulating plates (5) sit, thus forming closed air spaces (6) in the thermal insulating jacket (1). The thermal insulating jacket (1) is arranged in the frame (22), which is joined with the base (7) of the biofermenter, in which there are channels (8), which open into the inner space (28) of the mobile biofermenter. Pipes (9) are laid in the channels (8), connected to the common source (10) of pressurised air and equipped with expiratory holes (11).<IMAGE>
Patent CZ-185394-A3 (CZ)
Title: Pharmaceutical preparation for improving antioxidative stage of a tissue and use thereof
Inventor: ENDER FERENC DR
IPC: A61P17/00
Filed: 1994-08-02
Abstract: The invention relates to the use of 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione (generic name: pentoxifylline) and/or 1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinolinium theophylline-7-acetate (Depogen) or monohydrate thereof for preparing a pharmaceutical composition suitable for improving the tissue antioxidant status. This status plays an important role in complications, occurring as a consequence of pathologically developed or artificially established anastomoses, particularly anastomosis of oesophagus and colon since these organs possess a very weak antioxidant protective system. The invention furthermore relates to the preparation of the above pharmaceutical compositions. The above active ingredients promote and accelerate the healing process of anastomoses by improving the tissue antioxidant status and besides, they retain their good inhibitory effect on the adhesion of anastomoses.
Patent CZ-200451-A3 (CZ)
Title: Device and method for filling a storage vessel of a vehicle with brake sand
Inventor: FEDERHEN BERND
IPC: B61K11/00
Filed: 2004-01-12
Abstract: The device for the filling of a supply container of especially a rail vehicle (12) with braking sand or loose material has a storage pipe with an inlet head (26) determining the feed direction of the sand and delivery direction for the air, and with a pipe (34) for delivery of sand to the vehicle. The inside diameter of the storage pipe is especially 150mm. The inlet head between an inlet pipe (27) for the sand and a ventilation passage has a shut-off component by which the feed passage for the sand is closed off in the direction of feed.
Patent CZ-201726-A3 (CZ)
Inventor: HAVEL BRONISLAV
IPC: F25B27/02
Filed: 2017-01-21
Abstract: Způsob komplexního zásobování budov energií z mobilního zdroje je řešen prostřednictvím spalovacího motoru (E) s vlastním dvojstupňovým chladícím obvodem, který pohání generátor (G) elektrického proudu a mrazící okruh (F1) a klimatizační okruh s tepelným čerpadlem (F2), přičemž činnost všech agregátů je řízena a optimalizována neznázorněným počítačem. Zařízení pro provádění tohoto způsobu sestává z motorového okruhu (M) se spalovacím motorem (E) k němuž jsou, přes třívývodovou převodovku (P) připojeny dva chladící okruhy - mrazící (F1) a klimatizační okruh s tepelným čerpadlem (F2) a generátor elektrického proudu (G), přičemž ke spalovacímu motoru (E) je přiřazen dvoustupňový chladící obvod motoru (1 a 2).
Patent CZ-204197-A3 (CZ)
Title: Absorption article with integral side closing barrier
Inventor: JORGENSON THOMAS PATRICK
IPC: A61F13/472
Filed: 1995-12-21
Abstract: Disclosed is an absorbent article (200) having a liquid-permeable cover (202), a liquid-impermeable baffle (206) and an absorbent (208) with longitudinal side portions positioned intermediate thereof. The cover (202) and/or baffle (208) extend beyond the longitudinal side portions to form longitudinal side edges of the absorbent article (200). The absorbent article further includes an integral side barrier (220, 220') formed by gathering the longitudinal side edges inward toward the absorbent (208). In a preferred embodiment, the integral, longitudinal side barriers (220) have a tensioning member (218) secured thereto.
Patent CZ-216893-A3 (CZ)
Title: Color chart bar
Inventor: BRUNI HANSPETER
IPC: B41F31/18
Filed: 1993-10-14
Abstract: A knife (12), designed as a flexible steel plate, for the ink fountain of an offset printing machine has segments (42) in the region of the working edge (38), which are bendable in zones to a varied extent relative to an ink ductor (34) by means of individually adjustable setting elements. The segmented ductor knife (10) is designed as an autonomous installation unit. It comprises two-part lateral jaws (14), attached on both sides of a knife carrier (16), each having an outer metal jaw (18) and an inner plastic jaw (26) which can be engaged resiliently against the end faces of the ink ductor (34) and against the knife (12). Said plastic jaw expediently has a groove which is recessed at least in the region of the knife (12) immersed in an ink bath and which is filled with an elastic sealing compound. At least the segments (42) of a knife (12) designed as a flexible metal plate, also in an autonomous installation unit, are completely covered on the top side with a glued-on flexible metal strip. <IMAGE>
Patent CZ-226098-A3 (CZ)
Title: APPARATUS FOR REMOVING SULFUR DIOXIDE {SOi2} FROM COMBUSTION PRODUCTS AND FOR PREPARING AMMONIUM SULFATE
Inventor: RISSE THEO DIPL FYZIK
IPC: C01C1/247
Filed: 1998-07-17
Abstract: Apparatus for removing SO2 from waste gas and producing ammonium sulphate solution comprises: (a) a scrubber (1) having a scrubbing zone (2), a distributor (3) above the zone (2) for feeding absorption fluid, and a gas permeable collector base (8) for fluid arranged below the scrubbing zone; (b) a device (4) for introducing ammonia water to the scrubbing zone (2); (c) an oxidising device (5) for oxidising ammonium sulphite and ammonium hydrogen sulphite to ammonium sulphate; (d) an absorption fluid cycle (9) which connects the collector base (8) to the device (5) and device (5) to the distributor (3); (e) a waste gas channel (6) for feeding the waste gas to the scrubber (1); (f) a sprayer (7) in the channel (6) for feeding a quenching fluid saturated with water vapour; and (g) a device (12) for recycling the fluid from the scrubber sump (11) to the sprayer (7). Ammonium sulphate from the oxidising device (5) is fed to the sump (11) via an injector (13). A waste pipe (14) is connected to the sump (11), from which an ammonium sulphate solution suitable for fertiliser production is withdrawn.
Patent CZ-229596-A3 (CZ)
Title: Epoxidation process of prochiral olefins, their catalysts and intermediates for preparing the catalysts
Inventor: BELL DAVID
IPC: C07C69/88
Filed: 1995-02-01
Abstract: A process for enantioselectively epoxidising a prochiral olefin, which process comprises reacting the prochiral olefin with a source of oxygen in the presence of a salen catalyst and a source of an electron donating ligand, characterised in that the donor ligand is isoquinoline N-oxide or a compound having donor ligand activity and having substantially the same solubility characteristics as isoquinoline N-oxide; and compounds used in such process. The catalyst (III) and intermediates for its preparation are also claimed in which M is a transition metal ion; A is a counter-ion if required; B, B', E and E' are independently selected from the group consisting of hydrogen aryl, C1-6 alkyl, silyl or aryl-C1-6 alkyl in which any aryl or alkyl moiety is optionally substituted or B' and B or E' and E together form a C2-6 polymethylene link; with the proviso that only one of the carbons marked with an asterisk is a chiral centre; R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are independently hydrogen, alkyl or alkoxy.
Patent CZ-231994-A3 (CZ)
Title: N-tert.butylandros-3,5-diene-17beta-carboxamide-3-carboxylic acid in polymorphous form and process for preparing thereof
Inventor: BAINE NEIL HOWARD
IPC: C07J41/00
Filed: 1993-03-24
Abstract: Polymorph "A" a novel polymorphic form of N-t-butyl-androst-3,5-diene-17 beta -carboxamide-3-carboxylic acid. Novel processes for preparing polymorph "A" are also disclosed.