baber/WOPTO huggingface dataset:
Patent EP-0524777-B1 (EP)
Inventor: DOECKE CHRISTOPHER WILIAM
IPC: C07D405/06
Filed: 1992-07-17
Granted: 2000-10-18
Abstract: A process for isolating a  beta -lactam compound with about 100% enantiomeric purity, of the formula <CHEM> where R1 is CH3, t-C4H9, C6H5CH2O, C6H5, C6H5OCH2 or C6H5CH2; from a haloalkane solvent, comprising diluting the solution with methyl t-butyl ether or methanol to precipitate the product. The products thus obtained are key intermediates in the synthesis of antibiotic agents. The process is appropriiate for large scale production.
Patent EP-0556297-B1 (EP)
Inventor: PRUETT ROY LAVELLE
IPC: C07B61/00
Filed: 1991-11-04
Granted: 1995-06-07
Abstract: Procédé de production d'imines et/ou d'amines aliphatiques à partir d'alcools aliphatiques monohydriques, tels que des oxo-alcools à poids moléculaire supérieur, y compris des alcools d'éther, comprenant les étapes suivantes: déshydrogénation de l'alcool en aldéhyde in situ en présence d'un catalyseur de déshydrogénation d'oxyde de zinc et/ou de sel ou d'hydroxyde de zinc et d'une quantité soluble d'une amine aliphatique primaire qui se condense immédiatement avec l'aldéhyde dans des conditions de reflux, avec une suppression continue de l'eau, pour produire l'imine aliphatique correspondante (base de Schiff). On peut produire l'amine aliphatique correspondante par réduction ou amination réductrice de l'imine de façon connue, pour former les amines primaires, secondaires ou tertiaires, au choix. L'étape de production de l'imine est très critique et on a découvert que le système de déshydrogénation avec catalyseur d'hydroxyde de zinc produit une conversion douce, économique et efficace de l'alcool en aldéhyde, réagissant avec l'addition graduelle d'amine primaire, associée à la suppression continue de l'eau de condensation, afin d'empêcher des réactions secondaires indésirables diminuant le rendement.
Patent EP-0563229-B1 (EP)
Inventor: FREEMAN DANIEL KENNETH
IPC: G10L19/083
Filed: 1991-12-20
Granted: 1999-11-10
Abstract: In a codebook excited speech coder, speech is analysed (200) to produce coefficients of a synthesis filter and (203, 204) the parameters of a long-term prediction filter (LTP) and a codeword indication one of a set of excitations (stored in 205), the results being transmitted to a receiver where they can be used to resynthesise the speech. The LTP and excitation analysis involve computation (224) of impulse response products (stored in 301, 302). Computation of new products is performed by adding additional terms to products already formed. Multiplication of these products by excitation terms is performed using a pointer table (303) storing precalculated addresses of locations in the store (301, 302). If some excitations are shifted versions of others, some addressed can be obtained by modifying other addresses. The LTP analysis (203) may include selection between a simple delay prediction and a prediction consisting of the sum of two differently delayed terms, to provide improved predictor delay resolution.
Patent EP-0560932-B1 (EP)
Inventor: HUNG MIEN-CHIE
IPC: C07K14/075
Filed: 1991-12-04
Granted: 1996-09-04
Abstract: PCT No. PCT/US91/09100 Sec. 371 Date Jun. 4, 1993 Sec. 102(e) Date Jun. 4, 1993 PCT Filed Dec. 4, 1991Disclosed are methods and compositions for the suppression of expression of the neu oncogene, as well as suppression of neu oncogene-mediated transformation, tumorigenesis and metastasis. The method disclosed involved introduction of adenovirus early 1A gene (the E1A gene) products into affected cells. These products, which are preferably introduced by transfection of the E1A gene into affected cells, serve to suppress neu gene expression as measured by a reduction of p185 expression. Furthermore, the E1A gene products surprisingly serve to suppress the oncogenic phenotype, as indicated by a reduction in cell growth, growth in soft agar, as well as tumorigenic and metastatic potential in vivo. The inventors propose that E1A gene products, or derivatives therefrom, may ultimately be employed a treatment modalities for neu-mediated cancers, such as cancers of the female genital tract and breast.
Patent EP-0566656-B1 (EP)
Inventor: SIEGEL ROBERT J
IPC: A61B18/12
Filed: 1992-01-09
Granted: 2000-08-16
Abstract: Dispositif d'angioplastie à ultrasons (10) comprenant un élément de transmission d'ultrasons allongé (20) pourvu d'une extrémité proximale pouvant être fixée à un dispositif produisant des ultrasons (2) et d'une sonde ou tête (22) distale bulbiforme (22) se trouvant sur son extrémité distale et servant à effectuer un traitement par ablation d'une lésion occlusive. L'élément de transmission d'ultrasons (20) peut être fabriqué à partir d'un ou plusieurs alliages métalliques superélastiques tels que NiTi (50 % atomique de Ni). Un passage (35) pour fil de guidage peut être pratiqué dans la tête ou la sonde distale (22) afin de permettre à un fil de guidage (34) de passer à travers celle-ci. Des parties de l'élément de transmission d'ultrasons (20) peuvent être incurvées ou pliées. D'autres parties de cet élément (20) peuvent être rétrécies. Une ou plusieurs ruptures (41, 42) superficielles peuvent être pratiquées sur la tête ou la sonde distale (22) pour améliorer l'efficacité du traitement. L'élément de transmission d'ultrasons (20) peut être pourvu d'une enveloppe externe (50) ou d'un revêtement d'une dureté accrue. Le dispositif (10) de la présente invention peut être intégré à un dispositif angioscopique (70).
Patent EP-0580720-B1 (EP)
Title: Ensemble a embouchure, a obturateur et a serrure servant a obturer la bouche d'un tuyau
Inventor: HAGENBERG HENDRIKUS
IPC: B60K15/04
Filed: 1992-04-16
Granted: 1995-07-05
Abstract: Ensemble servant à obturer la bouche d'un tuyau et comportant: une embouchure (10) dont les deux extrémités sont ouvertes, et destinée à se relier à la bouche du tuyau; un obturateur (14) servant à obturer l'une des extrémités de l'embouchure (10) et possédant une partie axialement saillante (16) destinée à s'engager dans l'embouchure (10); et une serrure (20) apte à prendre une position de verrouillage ou de déverrouillage en fonction de son actionnement par une clé (22). Dans la position de verrouillage, l'obturateur (14) monté sur l'embouchure (10) est fixé à celle-ci et l'on peut introduire la clé dans la serrure et la retirer de celle-ci, et dans la position de déverrouillage, l'obturateur (14) est libre de se déplacer par rapport à l'embouchure (10) et la clé est bloquée dans la serrure. Ladite serrure (20) est solidaire de l'obturateur (14), dont la partie saillante (16) comporte: un plateau de verrouillage (24) dont le déplacement est solidaire de celui de la clé (22) et qui, lorsque la serrure (20) se trouve dans sa position de verrouillage et que l'obturateur (14) est en prise avec l'embouchure correspondante (10), entre en prise avec ladite embouchure (10) de manière à assurer le verrouillage par voie mécanique de l'obturateur sur l'embouchure; ainsi qu'un goujon de blocage (48, 50) servant, lorsque la serrure se trouve dans sa position de déverrouillage, à bloquer le plateau de verrouillage (24) pendant que l'obturateur (14) n'est pas sur l'embouchure (10), et à libérer ledit plateau de verrouillage (24) pendant que l'obturateur (14) se trouve sur l'embouchure correspondante. Ladite embouchure (10) et ledit obturateur (14) sont pourvus d'éléments magnétiques coopérants dont un premier est solidaire de l'embouchure (10) et dont un second est couplé au goujon de blocage (48, 50) pour l'actionnement de celui-ci.
Patent EP-0600892-B1 (EP)
Inventor: ANTOINE ROBERT
IPC: A61H33/02
Filed: 1992-04-10
Granted: 1996-02-28
Abstract: PCT No. PCT/FR92/00322 Sec. 371 Date Dec. 21, 1993 Sec. 102(e) Date Dec. 21, 1993 PCT Filed Apr. 10, 1992 PCT Pub. No. WO92/18087 PCT Pub. Date Oct. 29, 1992.The device comprises a bathtub (2), injection orifices (5) associated with supply devices (12, 20) for producing hydrodynamic jets directed interiorly of the bathtub (2), and control units (22, 25, 27) for orienting in a synchronized manner the hydrodynamic jets issuing from the injection orifices (5) disposed on side surfaces (3, 4) of the bathtub (2). The control units are arranged such that, when they downwardly orient a hydrodynamic jet issuing from an injection orifice disposed on one side surface of the bathtub, they simultaneously upwardly orient a hydrodynamic jet issuing from an injection orifice disposed on the opposite side surface of the bathtub, and vice versa.
Patent EP-0596964-B1 (EP)
Inventor: HILL AXEL
IPC: G21C9/04
Filed: 1992-07-28
Granted: 1996-01-03
Abstract: Un premier courant partiel (f11) du mélange H2-air-vapeur (f1) est conduit à travers un premier canal (R) et est recombiné par contact avec une première paroi de canal (r1) comportant un revêtement catalytique. Un deuxième courant partiel (f12) dudit mélange est conduit, en plus du premier courant partiel (f11), à travers un deuxième canal (2) avec une deuxième paroi de canal (r2), où il est allumé en passant au niveau des éléments d'allumage (z, z1, z2, z3), de préférence métalliques, portés à la température d'inflammation de l'hydrogène, en atteignant ou en dépassant la limite d'inflammabilité. La chaleur dégagée lors de la réaction catalytique dans le premier canal (R) est transférée prioritairement, du moins en partie, sur le deuxième canal (Z), pour le préchauffer. Ce nouveau procédé fonctionne aussi bien aux limites d'inflammabilité inférieures que supérieures et permet la recombinaison même en présence de concentrations d'hydrogène non inflammables. Est également décrit l'appareil permettant d'appliquer le procédé.
Patent EP-0565668-B1 (EP)
Inventor: MALMROS MARK J
IPC: A61K31/54
Filed: 1992-10-07
Granted: 1999-06-23
Abstract: A biological stain composition contains toluidine blue O and a pharmaceutically acceptable oxidizing agent to convert any leuco toluidine blue O to the chromo form. A dry composition for preparing the stain includes the toluidine blue O, the oxidizing agent and an effervescent agent. These compositions are preferably buffered to improve shelf stability and clinical consistency. Compositions for intra-oral application contain a flavoring agent.
Patent EP-0555723-B1 (EP)
Inventor: BRANDES MANFRED DR
IPC: H04L25/52
Filed: 1993-02-02
Granted: 1998-10-14
Abstract: According to the object, the linear distortion due to inadequate transmission of low-frequency spectral components and superimposed low-frequency interference sources occurring during the transmission of digital signals is to be eliminated. Networks as used in quantised feedback, the frequency response and variation with time of which must be matched to one another, are not to be used. The method according to the invention has the effect that from the bivalent digital signal a trivalent signal is produced by clamping the voltage for a short time to a reference voltage UO at the detection point under control by the bit clock. The value of the digitial signal is determined by a logic operation from the voltage values of successive bit periods and is provided as regenerated signal at the predetermined bit clock rate. The method provides for regenerating even multi-valent signals. It is preferably used in PCM engineering. <IMAGE>
Patent EP-0648500-B1 (EP)
Inventor: KARSANOV NIKOLAI VASILIEVICH
IPC: A61K38/17
Filed: 1993-08-13
Granted: 1998-11-18
Abstract: The invention relates to cardiology and presents a cardiotropic agent REFRAKTERIN based on the cardiac glycoside and the  beta -adrenergic stimulator and further contains nicotinamide adenine dinucleotide, cytochrome C and inosine. REFRAKTERIN restores the contractility and increases the reserves of the myocardium in the pronounced and severe form of heart failure.
Patent EP-0591683-B1 (EP)
Inventor: SHIMAKURA MASAMI
IPC: G09G5/18
Filed: 1993-09-03
Granted: 1998-12-16
Abstract: A display control apparatus includes a display data memory for storing display data, a display controller capable of sequentially reading out the display data stored in the memory and transferring the readout display data to the display device at a predetermined period and capable of performing a partial rewrite operation of the display data stored in the memory, a rewrite detector for detecting an address for accessing the display data memory to cause the display controller to perform the partial rewrite operation, and a transfer permitting unit for reading the address detected by the rewrite detector and permitting transfer of only the display data of the read address to the display controller. <IMAGE>
Patent EP-0594203-B1 (EP)
Inventor: STEINHAUSER PIUS
IPC: A61L2/02
Filed: 1993-10-22
Granted: 1998-08-12
Abstract: In a device (1) for cleaning and/or disinfecting and/or care of medical or dental instruments, especially handpieces (4), with a rinsing vessel (2) for receiving at least one instrument and with an ultrasonic cleaning device with an ultrasonic generator (9) located at the rinsing vessel (2), the rinsing vessel (2) preferably has a horizontal cross-section that differs from a rectangular or square cross-section. <IMAGE>
Patent EP-0586037-B1 (EP)
Inventor: HUGHES GREGORY G
IPC: F28F9/18
Filed: 1993-03-30
Granted: 1997-05-21
Abstract: Low pressure resistance in a radiator for use in the cooling system of an internal combustion engine or other heat exchanger may be overcome in a construction including a core (20) defined by a plurality of elongated spaced, parallel tubes (26) with fins (28) extending between adjacent tubes, and header and tank assemblies (22, 24) at opposite ends of the core and attached thereto to be in fluid communication with the tubes (26). Each header and tank assembly (22, 24) includes an elongated housing (40, 104) including an interior passage (34) of circular cross-section and an external, generally planar surface (48, 98). Elongated recesses (46, 110, 112) are disposed in the exterior of the housing, one to each side of the planar surface (48, 98) and an elongated channel having spaced legs (56) interconnected by a base (54) is fitted to the housing with the base (54) abutted to or adjacent to the planar surface (48, 98) with the legs extending partially about the housing to be received in the recesses (46, 110, 112). Openings (52, 84, 103, 106) establish fluid communication between the passages (34) and the planar surface (48, 98) and a plurality of openings (60) in the base (54) sealingly receive the ends (70) of the tubes (26) in the core (20). <IMAGE>
Patent EP-0573218-B1 (EP)
Inventor: YANAGISAWA HIROAKI
IPC: A61K31/4174
Filed: 1993-05-27
Granted: 2001-03-07
Abstract: Compounds of formula (I): <CHEM> [in which: R<1> is hydrogen, alkyl, cycloalkyl or alkanoyl; R<2> is a single bond, alkylene or alkylidene; R<3> and R<4> are each hydrogen or alkyl; R<6> is carboxy or tetrazol-5-yl; and X is oxygen or sulphur]; and pharmaceutically acceptable salts and esters thereof are AII antagonists and can be used for the treatment and prophylaxis of hypertension and cardiovascular diseases.
Patent EP-0660247-B1 (EP)
Inventor: SHYU RONG-FUH
IPC: G06F17/14
Filed: 1993-12-23
Granted: 2003-07-23
Abstract: A discrete cosine transform (DCT) apparatus, capable of generating one-dimensional and two-dimensional DCT and inverse DCT results, uses six-stage DCT/IDCT fast algorithms to process a sequence of input data (Din) of an 8 x 8 data block. Each of the different stages of the DCT/IDCT fast algorithms involves a number of butterfly operations, which can be performed by a butterfly operation unit (2) of the DCT apparatus, or a number of intrinsic multiplications, a number of post-addition multiplication operations, or a number of post-multiplication subtraction operations, all of which can be performed by a multiplication operation unit (3). A control unit (6) of the DCT apparatus permits the use of a single butterfly operation unit (2) and a single multiplication operation unit (3) to perform the different stages of the DCT/IDCT fast algorithms. The results of each stage of the DCT/IDCT fast algorithms are stored in a data register unit (4) of the DCT apparatus to serve as inputs for the succeeding stages of the DCT/IDCT fast algorithms. <IMAGE>
Patent EP-0571241-B1 (EP)
Inventor: JOUSLIN DE NORAY ERIC
IPC: C08J5/18
Filed: 1993-05-04
Granted: 1997-08-13
Abstract: Flame-resistant thermoplastic compositions based on polyamide comprising a mixture of polyamide(s), of Sb2O3 and/or of melamine cyanurate and of Mg(OH)2. They may contain glass fibres, inorganic fillers and/or additives such as colorant(s), lubricant(s), stabilisers against heat or light, impact strength improvers, plasticisers and antioxidants. They are prepared by mixing constituents in powdered form, introducing the mixture with the polyamide into an extruder and incorporating glass fibres into the molten material. These compositions are employed especially for the production of moulded or extruded objects, of films or of composite materials exhibiting an excellent fire resistance (V0 under 1.6 mm) and good mechanical characteristics.
Patent EP-0671373-B1 (EP)
Inventor: ANDREEV ALEXANDR ANATOLIEVICH
IPC: C05G5/23
Filed: 1992-12-28
Granted: 1999-10-13
Abstract: The essence of the invention lies in the fact that the solid product, which is synthesized in the reaction vessel (1) from the base constituents and is the raw material used to produce the salt and/or fertilizer solution, is obtained in the form of a sludge which is loaded into the container (2) at predetermined temperatures such that the product crystallizes out until the desired solidification is achieved. The same container (2) is used for the transportation and storage of the solidified crystals. A solution of salt and/or fertilizer at the required concentration is produced immediately before being fed into the consumer device (4), the same container (2) being used for dissolving the crystals. The product can be trans-shipped as required.
Patent EP-0640152-B1 (EP)
Inventor: MAY HANS JOSEF
IPC: C23D5/04
Filed: 1993-04-30
Granted: 1995-12-06
Abstract: The proposal is for a process for enamelling annealed endless steel strips by coating them with powder and subsequently stoving the, in which the strips are coated with powder immediately after the annealing process and then stoved.
Patent EP-0636095-B1 (EP)
Inventor: KIM JISU
IPC: B65D73/00
Filed: 1993-04-12
Granted: 1996-07-10
Abstract: A package for displaying a plurality of safety razors is provided which includes opposed front and rear panels articulated to one another to define an enclosure. Each of the opposed front and rear panels has an elongated slot provided therein defining a blade head maintaining area for the razors. An upper panel extends from the front panel to the rear panel above the blade head maintaining area. Structure projects into at least one of the opposed slots for inhibiting movement of the plurality of razors within the blade head maintaining area. In addition, a passageway descends from at least one of the slots in the opposed panels for permitting individual removal of the plurality of razors from the package while inhibiting the egress of the remaining razors therethrough.
Patent EP-0642682-B1 (EP)
Inventor: MUELLER FRANZ
IPC: G06F17/00
Filed: 1993-05-27
Granted: 1998-07-08
Abstract: A process is disclosed for processing analogical and binary measurement values detected by sensors in a water or caloric power plant. The analogical and binary measurement values detected in steady and unsteady operational states, such as run-ups, run-outs, load sheddings and emergency conditions, are supplied to a relational real time data bank (12) after having been converted into corresponding digital signals and correspondingly prepared and pre-processed (22, 23). The real time data bank (12) is distributed in a digital computer system which consists of at least two digital computers mutually linked by a ring and having a central unit, a storage unit and a display device. The digital computer system is further provided with an expert system (13, 14) and with calculation modules (15, 16, 17, 18) which determine the instantaneous machine data from the measurement values. These are compared by the expert system (13, 14) with the calculated machine data or with the machine data measured in the original state and stored in the real time data bank (12), then evaluated. In addition, the expert system (13, 14) carries out a trend analysis (25) and an on-line diagnosis of the state of the power plant. Since with this process the instantaneous state of the generator and of the turbines is always known, maintenance operations according to fixed schedules are no longer required and a state-dependent maintenance can be adopted.
Patent EP-0646144-B1 (EP)
Inventor: BAUMANN ROBERT
IPC: C08K5/01
Filed: 1993-06-14
Granted: 1997-01-29
Abstract: This invention relates to a polyurethane foam stabilizing additive that comprises from about 10 to about 50 weight percent a hydrocarbon oil, and in from about 90 to about 50 weight percent a polyester polyol which is a solid at room temperature. Use of the additive in a polyurethane foaming process provides for improved dimensional stability of the resulting foam. The additive is especially of value when preparing water blown polyether polyol-based polyurethane foam useful, for example, in sealant applications.
Patent EP-0649435-B1 (EP)
Inventor: KAPOOR ARCHANA
IPC: A61K39/00
Filed: 1993-06-28
Granted: 2006-04-05
Abstract: Nucleic acid encoding four novel immunodeterminant protein antigens of M. bovis BCG, which is a vaccine strain for tuberculosis, have been isolated. These genes were isolated as immunoreactive recombinant clones from a genomic library of M. bovis BCG DNA and screened with sera collected from tuberculosis patients. The BCG DNA expressed an antigen of Mr 90 kD, and an ORF encoding 761 amino acids encoding a protein of deduced molecular weight 79 kD, was indentified to encode a membrane bound, ion-motive ATPase of M. bovis BCG. The approach described here can be used to identify immunogens of mycobacteria. The well-characterized M. bovis BCG antigens can be used in the prevention, diagnosis and treatment of tuberculosis. The 79 kD antigen is also useful in the design of recombinant vaccines against different pathogens. The sequence of the 79 kD membrane-associated polypeptides also are useful for the development of specific PCR amplification based diagnostic procedures for the detection of mycobacteria. The promoter of the 79 kD antigen is useful for expressing homologous and/or heterologous antigens in mycobacteria.
Patent EP-0611502-B1 (EP)
Inventor: POHJAKALLIO PEKKA
IPC: H04W76/04
Filed: 1993-08-13
Granted: 1999-05-12
Abstract: The invention relates to a method for the transfer of user data in packet format in a digital cellular radio system comprising at least one organization channel common to all mobile stations (MS) for sending pages, connection requests, and channel assignements, so as to establish an actual connection on another channel. In the invention, the user data is transferred in packet format from the mobile stations (MS) to the base station (BTS1-BTS4) in modified paging messages which are sent on the organization channel interleaved with normal paging messages but will not result in a normal connection establishment.