baber/WOPTO huggingface dataset:
Patent EP-4198126-A1 (EP)
Inventor: SCHUMANN KATHRIN
IPC: C12N15/10
Filed: 2021-12-16
Abstract: The present invention relates to a composition comprising a DNA-dependent protein kinase catalytic subunit inhibitor and a 53BP1 inhibitor. The present invention also relates to a composition comprising a DNA-dependent protein kinase catalytic subunit inhibitor and a 53BP1 inhibitor for use in medicine. Furthermore, the present invention relates to a gene editing enhancing composition comprising a DNA-dependent protein kinase catalytic subunit inhibitor and a 53BP1 inhibitor. Besides, the present invention relates to a gene editing method comprising the sequential steps of: (i) enriching isolated cells, followed by activating said isolated cells by pre-determined surface antigens; (ii) adding a composition according to the invention to said cells simultaneously to transfecting said cells two days after step (i); (iii) adding a stimulant to said cells five days after step (i); (iv) analyzing the genome editing efficiency and viability of said cells by fluorescent-activated cell sorting. Moreover, the present invention relates to an engineered cell obtained by the gene editing method of the present invention. Additionally, the present invention relates to the use of the composition comprising a DNA-dependent protein kinase catalytic subunit inhibitor and a 53BP1 inhibitor in gene editing.
Patent EP-4027147-A1 (EP)
Inventor: BUCHWALD MARKUS
IPC: G01N35/00
Filed: 2021-12-21
Abstract: Die Erfindung betrifft ein Abfalltrennsystem (1) zum Trennen von Abfall für ein automatisches Analysegerät, das Abfalltrennsystem (1) umfassend einen ersten Abfallbehälter (2) und einen zweiten Abfallbehälter (3), eine Abfallverbringvorrichtung (4) zum Verbringen von Abfall in den ersten (2) oder den zweiten Abfallbehälter (3) und eine Steuervorrichtung (5) zur Steuerung der Abfallverbringvorrichtung (4), wobei die Steuervorrichtung (5) so konfiguriert ist, dass die Abfallverbringvorrichtung (4) Abfall einer ersten Abfallklasse in den ersten Abfallbehälter (2) verbringt und Abfall einer zweiten Abfallklasse in den zweiten Abfallbehälter (3) verbringt.
Patent EP-4119931-A1 (EP)
Inventor: BANON ALEXANDRE ANTOINE BENJAMINE MARIE
IPC: G01N21/65
Filed: 2021-07-15
Abstract: The invention relates to computer-implemented signature determination method (100) for determining a spectral signature corresponding to a target, the method comprising: 
- based on a training dataset including at least one first spectrum of a first sample labeled as including the target and at least one second spectrum of a second sample labeled as not including the target, each first spectrum and each second spectrum being acquired over a predetermined spectral range, training (110) a model to output, for each channel of the predetermined spectral range, a corresponding relevancy score representative of a relevancy of the channel for determining the presence or the absence of the target in a non-labeled sample based on a non-labeled spectrum acquired from said non-labeled sample; 
- computing (120) the spectral signature, a value of the spectral signature for each channel of the predetermined spectral range depending on the outputted relevancy score for said channel.
Patent EP-4194084-A1 (EP)
Title: Metal organic frameworks for the selective capture of volatil organic compounds comprising carboxylic acid functional group(s)
Inventor: SEVERINO NEVES MARIA INÈS
IPC: B01D53/02
Filed: 2021-12-10
Abstract: The present invention relates, inter alia, to the use of porous crystalline solids constituted of a metal-organic framework (MOF) for the selective capture of volatile organic compounds (VOCs) comprising carboxylic acid functional group(s). 
     The MOF solids of the present invention can be used for the purification of air, for example for the selective capture of VOCs comprising carboxylic acid functional group(s) from outdoor air. It may be used for art preservation, such as the conservation of cellulose derivate films, for indoor air purification systems such as HEPA air filters, adsorbent purifiers, kettle filters, fette filters, honeycomb filters or air conditioning filters, for outdoor air purification systems such as gas mask, nose filter, adsorption columns or chimney filters, and in cosmetic applications such as deodorants, anti-odor shampoo, hygienic protection products, wipes or diapers.
Patent EP-4192060-A1 (EP)
Title: Management of subscriber profiles on an euicc
Inventor: GARCIA FARRÉS ANDREU
IPC: H04W8/18
Filed: 2021-12-01
Abstract: The present invention relates to methods, devices, and computer program products for managing subscriber profiles on an eUICC 130. Within that context, a method for managing subscriber profiles stored in an eUICC 130 comprises an ISD-R 131 and an API 132 implemented on the eUICC 130, the API 132 providing for executing or executing via the ISD-R 131 a profile management operation concerning a subscriber profile of the eUICC 130. Further, an application 133 installed on the eUICC 130 instructs the API 132 to execute the profile management operation concerning the subscriber profile. The invention further relates to an according eUICC 130, a device 150 having embedded therein a eUICC 130 and computer program products representing the API 132 and the application 133.
Patent EP-4093503-A1 (EP)
Title: Bestrahlungsvorrichtung
Inventor: GERSTENMEIER JÜRGEN
IPC: A61N5/06
Filed: 2021-01-22
Abstract: Die Erfindung betrifft eine Bestrahlungsvorrichtung (1) zur Beaufschlagung eines Bestrahlungsobjekts mit Licht, umfassend mindestens ein Leuchtmittel (2) mit einer Identifikationseinheit (3), die Leuchtmittelspezifische Informationen beinhaltet; einen Rahmen (4), insbesondere einen reflektierenden Rahmen (4), mit mindestens einer Leuchtmittelfassung (5), an welchem das mindestens eine Leuchtmittel (2) angeordnet ist durch formschlüssiges Einfügen in die Leuchtmittelfassung (5); einen Bereich (6), der ein Detektionsfeld (B) einer Kommunikationseinrichtung (7) ermöglicht; wobei die Identifikationseinheit (3) am mindestens einen Leuchtmittel (2) derart positioniert ist, so dass sich die Identifikationseinheit (3) durch das formschlüssige Einfügen in die Leuchtmittelfassung (5) innerhalb des Detektionsfelds (B) befindet.
Patent EP-4282156-A1 (EP)
Inventor: JOSHI URVANG
IPC: H04N19/117
Filed: 2021-01-19
Abstract: Image coding using guided machine learning restoration may include obtaining reconstructed frame data by decoding, obtaining a restored frame by restoring the reconstructed frame, and outputting the restored frame. Obtaining the restored frame may include obtaining a reconstructed block, obtaining guide parameter values, obtaining a restored block, and including the restored block in the restored frame. Obtaining the restored block may include inputting the reconstructed block to an input layer of a trained guided convolutional neural network, wherein the neural network is constrained such that an output layer has a defined cardinality of channels, obtaining, from the output layer, neural network output channel predictions, obtaining a guided neural network prediction as a linear combination of the guide parameter values and the neural network output channel predictions, and generating the restored block using the guided neural network prediction.
Patent EP-4103432-A1 (EP)
Title: Straffvorrichtung für eine sicherheitsgurtkomponente
Inventor: ZORGEL ZOLTAN
IPC: B60R22/195
Filed: 2021-02-09
Abstract: Die vorliegende Erfindung betrifft eine Straffvorrichtung für eine Sicherheitsgurtkomponente und ein Verfahren zur Herstellung einer solchen Straffvorrichtung, mit - einem Gasgenerator (2) zur Erzeugung eines Druckgases, - einem von dem Druckgas antreibbaren Kolben (4), - einem an den Kolben (4) angeschlossenen Zugseil (8), welches mit einer in eine Straffbewegung zu versetzenden Sicherheitsgurtkomponente verbindbar ist, und - einem Strafferrohr (1) zur Aufnahme und Führung des Kolbens (4), dadurch gekennzeichnet, dass - der Gasgenerator (2) im Strafferrohr (1) angeordnet ist, - das Strafferrohr (1) zwischen dem Gasgenerator (2) und dem Kolben (4) eine Ausnehmung (13) in seinem Mantel aufweist und - eine Seilumlenkung (14) vorgesehen ist, mit der das Zugseil (8) durch die Ausnehmung (13) aus dem Strafferrohr (1) herausgeführt ist.
Patent EP-4102981-A1 (EP)
Title: Amidon poreux utilisé en tant qu'agent gonflant dans des gommes à mâcher
Inventor: HASJIM JOVIN
IPC: A23G4/10
Filed: 2021-02-12
Abstract: La présente invention concerne l'utilisation d'amidon poreux comme agent gonflant dans une gomme à mâcher. La présente invention concerne également un procédé de fabrication de la gomme à mâcher et une composition de gomme à mâcher comprenant de l'amidon poreux en tant qu'agent gonflant.
Patent EP-4118023-A1 (EP)
Title: Procédé de formation d'une structure de guidage pour guider une cabine d'ascenseur dans une gaine d'ascenseur
Inventor: CAMBRUZZI ANDREA
IPC: B66B19/00
Filed: 2021-03-02
Abstract: L'invention concerne un procédé de formation d'une structure de guidage (5) dans une gaine d'ascenseur (1). La structure de guidage (5) est conçue pour guider une cabine d'ascenseur pendant qu'elle se déplace verticalement dans la gaine d'ascenseur (1). Le procédé comprend les étapes suivantes : le déplacement d'un outil (7), par exemple un outil de fraisage, verticalement le long de la gaine d'ascenseur (1), l'outil (7) étant positionné avec précision en termes de sa position horizontale à l'intérieur de la gaine d'ascenseur (1), et la formation de la structure de guidage (5) par enlèvement de matière d'une paroi de gaine (3) de la gaine d'ascenseur (1) au moyen de l'outil (7).
Patent EP-4118735-A1 (EP)
Inventor: MAITERTH EDUARD
IPC: H02K29/06
Filed: 2021-03-03
Abstract: Die Erfindung betrifft eine Antriebseinrichtung (1) für eine Bremsvorrichtung eines Kraftfahrzeugs, mit einer ein Gehäuse (5) aufweisenden elektrischen Maschine (2), die einen in dem Gehäuse (5) drehbar gelagerten Rotor (4) aufweist, und mit einer Rotorlagesensoreinrichtung (7), die eine Leiterplatte (8) mit zumindest einem dem Rotor (4) zugeordneten Sensorelement aufweist, wobei die Leiterplatte (8) kreisringscheibenförmig ausgebildet und koaxial zu einer Rotationsachse des Rotors (4) angeordnet ist. Es ist vorgesehen, dass die Leiterplatte (8) durch zumindest eine Rastverbindung (17) in oder an der elektrischen Maschine (2) befestigt ist.
Patent EP-4121311-A1 (EP)
Inventor: MIGNONAT CÉDRIC
IPC: B60J11/04
Filed: 2021-03-17
Abstract: The invention relates to a hail protection tarpaulin (2) for a vehicle (100). The tarpaulin comprises at least one ductile intermediate layer (22) with a low shrinkage rate, made up of at least one type of vibroabsorbent elastomer arranged in crystalline viscoelastic microcells, capable of absorbing and horizontally dispersing the shocks produced by the impact of the hail on the hail protection tarpaulin (2). The invention also relates to a storage mechanism (4) for a hail protection tarpaulin (2) as well as a hail protection system.
Patent EP-4127248-A1 (EP)
Inventor: BRAMBATI CHIARA
IPC: C12Q1/70
Filed: 2021-03-31
Abstract: The present invention is directed to methods for assaying for the presence of SARS-CoV-2 in a sample, including a clinical sample, and to oligonucleotides, reagents and kits useful in such assays. In particular, the present invention is directed to such assays that are rapid, accurate and specific for the detection of SARS-CoV-2 using labeled oligonucleotides hybridizing to the ORFlab and/or S gene.
Patent EP-4127045-A1 (EP)
Inventor: PFAENDNER RUDOLF
IPC: C07C59/52
Filed: 2021-03-25
Abstract: Die vorliegende Erfindung betrifft die Verwendung von spezifischen Hydroyzimtsäuresalzen zur Stabilisierung von organischen Materialien. Die Erfindung betrifft zudem ein entsprechend durch Einarbeitung eines spezifischen Hydroxyzimtsäuresalzes stabilisiertes organisches Material sowie ein Verfahren zur Stabilisierung von organischen Materialien. Daneben wird ein spezifisches Aluminiumsalz einer Hydoxyzimtsäure beschrieben, das sich als organischer Stabilisator eignet. Des Weiteren betrifft die vorliegende Erfindung eine Stabilisator‐ Zusammensetzung, die ein entsprechendes Hydroxyzimtsäuresalz beinhaltet.
Patent EP-4315675-A1 (EP)
Inventor: HAKOLA SAMI-JUKKA
IPC: H04L1/08
Filed: 2021-04-01
Abstract: Systems, methods, apparatuses, and computer program products for facilitating robustness for synchronization signal block (SSB) are provided. A network node may attempt to transmit SSBs in first positions. For example, the network node may perform a listen-before-talk (LBT) procedure prior to transmitting the SSBs, and transmissions of the SSBs may fail or succeed based on failure or success of the LBT procedure. If the transmissions fail, the network node may attempt to transmit the failed SSBs in second SSB positions. For example, the second SSB positions may be associated with the first positions, and may be reserved for retransmission of SSBs that fail in the corresponding first positions. If the network node transmits the SSBs, the UE may perform various operations described herein including, e.g., determining whether the SSBs were transmitted in the first positions or the second positions and/or an SSB index or timing.
Patent EP-4133127-A1 (EP)
Inventor: PRESCOTT RALPH
IPC: D21F1/02
Filed: 2021-04-09
Abstract: La présente invention concerne un procédé de régulation de l'écoulement de tranches de pâte liquide ayant au moins deux pâtes liquides constituantes à travers une caisse d'arrivée pour une machine de fabrication de papier. Ledit procédé consiste : à entrer une vitesse de fil de la machine de fabrication de papier ; à déterminer une valeur de consigne pour la vitesse du jet sur la base de la vitesse du fil ; à déterminer une valeur de consigne de pression du collecteur pour au moins deux collecteurs afin de générer la vitesse de jet déterminée par la consigne de vitesse de jet, chaque collecteur approvisionnant au moins l'une des deux pâtes liquides constituantes à la caisse d'arrivée ; et à réguler l'écoulement de tranches en : générant une première commande de vitesse à une première pompe à pâte liquide pour générer une pression du collecteur déterminée par la valeur de consigne de pression du collecteur dans un premier collecteur ; et à générer une seconde commande de vitesse vers une seconde pompe à pâte de liquide afin de générer la pression du collecteur déterminée par la valeur de consigne de pression du collecteur dans un second collecteur.
Patent EP-4150754-A1 (EP)
Inventor: SPRENGER HELGE
IPC: B60L15/20
Filed: 2021-04-30
Abstract: L'invention concerne la commande d'un système d'entraînement électrique, une plage de commande pour la fréquence de commutation d'un convertisseur de puissance dans un tel système d'entraînement étant adaptable lorsque la courbe de fréquence de rotation ou la courbe de couple de la machine électrique est prise en compte. De cette manière, des irritations psycho-acoustiques peuvent être évitées.
Patent EP-4140153-A1 (EP)
Title: A cluster-based approach to positioning of vehicles in vehicle platooning or autonomous trucking
Inventor: CHOI CHANG-SIK
IPC: H04W4/02
Filed: 2021-04-19
Abstract: A user equipment in a vehicle (v-UE) may transmit ranging signals, sometimes referred to as physical ranging signals (PRS), via inter-vehicle messages. The vehicle may be designated as a representative of a cluster of vehicles, e.g., in a vehicle platoon, and may broadcast and receive PRS on behalf of the cluster, while no other vehicles in the cluster broadcast PRS. PRS received from single representative vehicle in a separate cluster may be used to determine the inter-cluster distance between the two clusters. If the inter-cluster distance falls below a predetermined threshold, the v-UE may instruct all other vehicles in its cluster to begin broadcasting PRS, so that each vehicle can determine its distance to all other vehicles. Accordingly, the overhead due to broadcast PRS may be minimized until, e.g., accurate positioning between vehicles is warranted.
Patent EP-4149974-A1 (EP)
Title: Recombinant proteins with ox40 activating properties
Inventor: LEVY YVES
IPC: C07K16/28
Filed: 2021-05-11
Abstract: The disclosure relates to the field of OX40 activating proteins. More specifically, it is disclosed herein recombinant proteins with OX40 agonist antibodies or their antigen-binding fragments fused or linked to OX40 ligand. Also disclosed is the advantageous use of such OX40 activating proteins, in particular for inducing immune responses directed to delivered antigens such as viral or cancer antigens, and/or for treating cancer.
Patent EP-4149560-A1 (EP)
Title: Composition de nanoparticules en tant que support pour des fragments immunogènes dérivés du hpv
Inventor: RIEMER ANGELIKA
IPC: A61K39/12
Filed: 2021-05-12
Abstract: L'invention concerne une composition de nanoparticules en tant que support pour des fragments immunogènes dérivés du HPV et l'utilisation de la composition à des fins médicales, en particulier pour une immunoprophylaxie ou une immunothérapie. L'invention concerne également un vaccin contenant la composition et/ou les nanoparticules.
Patent EP-4161756-A1 (EP)
Inventor: AUSEN RONALD W
IPC: B29C48/11
Filed: 2021-05-05
Abstract: A web. The web includes an array of discrete polymeric tubes, wherein the cross-section of each polymeric tube has a non-circular shape; wherein adjacent polymeric tubes has a bond region; wherein polymeric tubes are hollow polymeric tubes; wherein adjacent polymeric tubes are connected at bond regions; and wherein the web is a continuous web.
Patent EP-4146852-A1 (EP)
Title: Bicomponent fibers including an ethylene/alpha-olefin interpolymer and polyester
Inventor: GARG AKANKSHA
IPC: C08L23/08
Filed: 2021-05-05
Abstract: Provided are bicomponent fibers with improved curvature. The bicomponent fibers comprise a first polymer region or first region and a second polymer region or second region. The first region according to embodiments of the present disclosure comprises an ethylene/alpha-olefin interpolymer and has a light scattering cumulative detector fraction (CDF LS ) of greater than 0.1200, wherein the CDF LS  is computed by measuring the area fraction of a low angle laser light scattering (LALLS) detector chromatogram greater than, or equal to, 1,000,000 g/mol molecular weight using Gel Permeation Chromatography (GPC). The second region comprises a polyester. The bicomponent fibers can be used for forming nonwovens.
Patent EP-4157613-A1 (EP)
Title: Drainage member design & ultrasonic welding method for attachment of catheter tube to drainage member
Inventor: O'DONNELL PAUL M
IPC: B29C65/00
Filed: 2021-05-04
Abstract: A urinary catheter is disclosed. The urinary catheter comprises a catheter tube having a proximal insertion end and a distal end. The catheter also comprises a drainage member. The drainage member includes a wall having an inner surface and an outer surface. The inner surface defines a drainage lumen having an opening in a proximal end of the drainage member. The distal end of the catheter tube is inserted through the opening of the proximal end of the drainage member and is located in the lumen. The wall of the drainage member has at least one window therethrough. The drainage member and the catheter tube are welded to one another at one or more welding sites in the vicinity of the window(s).
Patent EP-4153143-A1 (EP)
Title: Process for preparing an active liposome, related compositions and uses
Inventor: NANNONI GIULIA
IPC: A61K9/16
Filed: 2021-05-17
Abstract: The present invention relates to a process for preparing an active liposome which comprises an active ingredient in a liposome. Furthermore, the present invention relates to said active liposome as such (per se), or obtained from such process. Furthermore, the present invention relates to a composition comprising said active liposome and, optionally, food-grade or pharmaceutical-grade additives and/or excipients.
Patent EP-4161306-A1 (EP)
Title: Three-part clasp for pumping garment
Inventor: WOLFF TOM
IPC: A41F1/00
Filed: 2021-06-09
Abstract: A three-part clasp for a pumping garment for hands-free pumping includes a male part, a first female part, and a second female part. The male part is attached to a shoulder strap of the pumping garment. The first female part is attached to an inner layer of the pumping garment, the inner layer including an aperture for insertion of a breast pump flange. The second female part is attached to an outer layer of the pumping garment. In a doubly fastened configuration, the first female part is connected to the male part, the second female part is connected to the male part, and the first female part and the second female part are arranged side-by-side or the second female part is configured to be stacked upon the first female part.
Patent EP-4158019-A1 (EP)
Inventor: SAVVA YIANNIS
IPC: C12N15/11
Filed: 2021-05-25
Abstract: Provided herein are compositions of engineered guide RNAs relating to providing or engineering a structural target to attract adenosine deaminase acting on RNA (ADAR) editing to a desired site and methods of use thereof. Further provided herein are compositions and methods relating to recombinant adenosine deaminase acting on RNA (ADAR) split guide RNAs (adar-sgRNA). In certain embodiments, the adar-sgRNA composition comprises two guides-one guide with an ADAR recruiting domain and a second guide with a 5' and/or 3' RNA targeting domain for forming a trimolecular complex at a mismatch site that serves to recruit ADAR. Binding of the two adar-split gRNAs to the target RNA forms a trimolecular complex which recruits ADAR enzymes to deaminate one or more mismatched adenosine residues in the adar-split gRNA RNA targeting domain: target RNA duplex. In certain embodiments, such compositions and methods will be useful for modifying a coding sequence of a desired protein.
Patent EP-4157570-A1 (EP)
Title: Production de dispositifs de coupe pcd exempts de catalyseur
Inventor: ZHAN GUODONG
IPC: B22F3/14
Filed: 2021-06-02
Abstract: Des dispositifs de coupe pour un trépan de forage peuvent être formés en fournissant un diamant polycristallin synthétisé exempt de catalyseur (PCD) ayant une dimension de section transversale d'au moins 8 millimètres ; en fournissant un substrat comprenant du carbure de tungstène ; et en fixant le PCD synthétisé au substrat comprenant du carbure de tungstène pour former un dispositif de coupe PCD.
Patent EP-4176271-A1 (EP)
Inventor: HUBER CHRISTIAN
IPC: G01P3/488
Filed: 2021-06-25
Abstract: Die vorliegende Erfindung betrifft einen Magnetfeldsensor (1), welcher dazu angepasst ist, die Drezahl und Drehrichtung eines rotierenden Objekts (20), das entweder selbst ein rotierendes Magnetfeld erzeugt oder ein bestehendes Magnetfeld entsprechend ablenkt, zu bestimmen. Hierzu kommt ein Chip (2) mit mindestens drei Magnetfeldmesselementen (2a, 2b, 2c) in Form eines 3D-Hall-Sensors zum Einsatz. Solche Magnetfeldsensoren (1) kommen insbesondere bei Nutzfahrzeugen zum Einsatz. Eine Normalrichtung auf die Tangentialebene des rotierenden Elementes definiert eine z-Richtung. Aus dem Signal eines in z-Richtung empfindlichen Sensorelementes wird jeweils mit dem Signal eines weiteren Sensorelements ein Differenzsignal gebildet. Die beiden entstehenden Differenzsignale weisen eine Phasenverschiebung auf, aus der sich die Drehrichtung ermitteln lässt. Ein generiertes Ausgangssignal enthält sowohl Information über die Drehrichtung als auch über die Geschwindigkeit.
Patent EP-4178357-A1 (EP)
Inventor: AL-AKHDAR WALID A
IPC: A01P13/02
Filed: 2021-06-28
Abstract: La présente invention concerne un procédé de régulation de la végétation indésirable dans un environnement aquatique dans lequel un plant de riz se développe. Dans le procédé de cette invention, une quantité herbicidement efficace de pendiméthaline ou d'une composition comprenant de la pendiméthaline est appliquée à l'environnement aquatique avant l'émergence de la végétation indésirable et après la germination des plantules de riz. Le procédé convient particulièrement à la régulation des adventices dans les rizières inondées.