baber/WOPTO huggingface dataset:
Patent CA-3083123-A1 (CA)
Inventor: KANDUL NIKOLAY P
IPC: C12N15/09
Filed: 2018-11-19
Abstract: Cette invention concerne des procédés de la technique de l'insecte stérile guidée par précision (pgSIT), comprenant des procédés pour diriger le sexage mâle dans un insecte génétiquement modifié et des procédés de production d'une descendance d'ufs d'insecte mâle stérile génétiquement modifié. Ces procédés comprennent l'intégration d'au moins une séquence d'acide nucléique dans un génome d'un premier insecte,la/les séquence(s) d'acide nucléique ayant au moins un premier polynucléotide de guidage ciblant une séquence génomique essentiellement femelle qui est requise pour une viabilité spécifique à la femelle, l'introduction d'une endonucléase dans un second insecte, et le croisement génétique du premier insecte et du second insecte, de sorte à produire une descendance exprimant l'endonucléase et la/les séquence(s) d'acide nucléique. Pour la stérilité mâle, un second polynucléotide de guidage cible une séquence génomique de stérilité mâle qui est requise pour une stérilité spécifique aux mâles.
Patent CA-3084807-A1 (CA)
Title: Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces
Inventor: ENSIGN LAURA
IPC: A61K31/542
Filed: 2018-12-07
Abstract: Hypotonic gelling vehicles are used as solubilizing agents for drugs and as a means to provide sustained drug delivery to a mucosal tissue. Solubilizing drugs at higher concentrations enhances drug penetration into the tissues of the body, while the hypotonic gelling vehicle further improves distribution of the drug over a larger surface area for increased absorption and sustained release for reduced side effects and longer duration of action.
Patent CA-3086220-A1 (CA)
Title: Therapeutic agent for nervous system disease
Inventor: TANAKA HIROYUKI
IPC: A61P9/00
Filed: 2018-12-20
Abstract: The purpose of this invention is to provide a drug which is useful in the treatment of nervous system disease. This drug, which contains vitamin B12 as an active ingredient, has an action of promoting the induction of M2 macrophages/microglia, an action of suppressing the induction of M1 macrophages/microglia, and an action of promoting nerve regeneration, and is extremely effective as a drug for the treatment of nervous system diseases, particularly central nervous system diseases such as cerebral infarction, dementia and spinal cord injury.
Patent CA-3090932-A1 (CA)
Title: Vehicle heating system
Inventor: ENGMAN OLA
IPC: B60H1/22
Filed: 2018-08-04
Abstract: A system (1) for heating a vehicle interior comprising at least one subsystem (2) for heat delivery to the vehicle's interior, cab or the like, at least one subsystem (3) for supplying electrical energy to the system (4) for heating, at least one subsystem (5) for controlling the system (1) and at least one subsystem (6) for storing electrical energy (2) so that heat delivery to the vehicle's interior, cab or the like comprises at least one heat delivery device (7). The heat delivery device (7) comprising at least one infra-heater and at least one air flow generating device (8). The said air flow generating device (8) creating an air flow that flows past the infra-heater allowing the airflow to absorb the heat energy which is a by-product of the infra-heater which results in a combination of convection heat and direct infra-heat. The system (1) provides a more even heat dissipation achieving higher efficiency, and that the system's (1) subsystem (6), for storing electric energy, includes at least one accumulator, separated from the other electrical components of the vehicle.
Patent CA-3091499-A1 (CA)
Inventor: HALLOUIN BAPTISTE
IPC: F01D9/06
Filed: 2019-02-28
Abstract: Assembly for a turbomachine (1), comprising an annular channel (6) designed to form a flow duct for a flow of gas between two turbine stages (2, 3) of the turbomachine (1), said channel (6) being bounded by a radially inner annular wall (7) and a radially outer annular wall (8), said walls (7, 8) being connected by hollow arms (16) that extend radially, a support (17) comprising a radially outer annular part (9) that is located radially outside the outer annular wall (8) of the annular channel (6), and a radially inner annular part (12) that is located radially inside the inner annular wall (7) of the annular channel (6), the outer and inner parts (9, 12) of the support (17) being connected by connecting parts (18) that extend radially, each connecting part (18) passing through one of the hollow arms (16) of the annular channel (6), in which at least one of the connecting parts (18) of the support (17) and the corresponding hollow arm (16) are connected to one another by at least one connecting partition (22), said connecting partition (22) comprising a frangible part (23) that is able to rupture when the mechanical stresses in said connecting partition (22) are greater than a certain value.
Patent CA-3092366-A1 (CA)
Title: Non-invasive nerve stimulation
Inventor: DRUKE MICHAEL BERNARD
IPC: A61N1/04
Filed: 2019-02-26
Abstract: A topical nerve stimulator patch and system are provided including a dermal patch; an electrical signal generator associated with the patch; a signal receiver to activate the electrical signal generator; a power source for the electrical signal generator associated with the patch; an electrical signal activation device; and a nerve feedback sensor.
Patent CA-3093048-A1 (CA)
Inventor: SYCHEV MAXIM BORISOVITCH
IPC: H04N19/80
Filed: 2018-03-26
Abstract: A method for inter prediction of a sample value of a current pixel of a plurality of pixels of a current block of a current frame of a video signal is proposed. The method (800) comprises: determining (801) a plurality of block-wise motion vectors related one-to-one to a plurality of blocks of the current frame; determining (803) a pixel-wise motion vector of the current pixel based on the plurality of block-wise motion vectors; determining one or more reference pixels in the reference frame based on the pixel-wise motion vector of the current pixel; and determining (805) an inter predicted sample value of the current pixel based on one or more sample values of the one or more reference pixels in the reference frame. Coding efficiency is thus improved.
Patent CA-3093834-A1 (CA)
Inventor: DERN CHARLES D
IPC: F26B21/06
Filed: 2019-03-13
Abstract: A system including a fluid manifold and an article; the manifold having a length and a width and a plurality of inlet or outlet ports and the article comprising an element disposed within the manifold adapted for adjustable lengthwise movement within the manifold; and is suitably employed to adjust shelf temperature in for example a freeze-drying apparatus.
Patent CA-3093934-A1 (CA)
Title: Apparatus for measuring properties of gases supplied to a patient
Inventor: PAYTON MATTHEW JON
IPC: A61M16/16
Filed: 2005-08-19
Abstract: - 23 -ABSTRACT The gases temperature supplied to a patient when the patient is undergoing treatment such as oxygen therapy or positive pressure treatment for conditions such as Obstructive Sleep Apnea (OSA) or Chronic Obstructive Pulmonary Disease (COPD) is often measured for safety and to enable controlling of the humidity delivered to the patient. The invention disclosed is related to measurement of properties, particularly temperature, of gases flowing through a heated tube, supplying gases to a patient, which utilises the heating wire within the tube. CA 3093934 2020-09-11
Patent CA-3095494-A1 (CA)
Inventor: CREW ANDREW P
IPC: C07D471/04
Filed: 2019-04-04
Abstract: The present disclosure relates to bifunctional compounds, which find utility as modulators of Kirsten rat sarcoma protein (target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a Von Hippel-Lindau, cereblon, Inhibitors of Apotosis Proteins or mouse double-minute homolog 2 ligand which binds to the respective E3 ubiquitin ligase and on the other end a moiety which binds the target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation, accumulation, and/or overactivation of the target protein are treated or prevented with compounds and compositions of the present disclosure.
Patent CA-3101474-A1 (CA)
Inventor: RUNDE DAVID
IPC: B60N2/12
Filed: 2019-05-28
Abstract: La présente invention concerne un ensemble siège d'automobile comprenant un système manuel pour faire coulisser l'ensemble siège d'une position assise à une position d'entrée facile à tangage. L'ensemble siège comprend un dispositif de retour automatique pour ramener automatiquement l'ensemble siège de la position d'entrée facile à tangage à la position assise, le dispositif de retour automatique pouvant être un module qui peut être ajouté sur un ensemble siège existant ayant des éléments d'entrée facile à tangage manuel. Le dispositif de retour automatique est libéré pendant le coulissement vers l'avant et le tangage de l'ensemble siège vers la position d'entrée facile, mais peut ensuite être actionné pour commander le coulissement de retour et le tangage de retour de l'ensemble siège vers l'arrière jusqu'à la position assise. Si l'élément coulissant de retour ou l'élément de tangage vers l'arrière est bloqué ou obstrué, le dispositif de retour automatique libère l'élément obstrué et permet à l'élément non obstrué restant de continuer à fonctionner pour terminer le coulissement de retour ou le tangage de retour jusqu'à ce que le blocage ou l'obstruction soit supprimé ou que le dispositif de retour automatique soit libéré.
Patent CA-3102748-A1 (CA)
Title: A communication apparatus
Inventor: JACOBS GYSBERT JOHANNES
IPC: G06F13/42
Filed: 2019-06-07
Abstract: A communication apparatus is disclosed with a communication controller that has a host-side communication interface for communicating with a host and a plurality of slave-side communication interfaces. Each slave-side communication interface has a plurality of electrical pins that are configurable to define a communication port that implements a selected communication protocol thereon. Each pin is in electrical communication with a slave socket having a predetermined layout. Each slave socket is configured to receive a protocol adapter that corresponds to the selected communication protocol and that is configured to facilitate communication between an external slave device and the relevant communication port.
Patent CA-3105220-A1 (CA)
Title: Extraction of polynucleotides
Inventor: BUNKERS GREGORY JAMES
IPC: G01N1/08
Filed: 2019-07-11
Abstract: The present invention relates to various methods and apparatus for extracting polynucleotides, particularly in soil samples. Further methods and apparatus of the present invention provide for additional processing of the polynucleotides, such as analysis and/or amplification. Still other methods and apparatus relate to applying a treatment to a plant or seed based on the analysis of the polynucleotide.
Patent CA-3108732-A1 (CA)
Title: Fused imidazopyridines as reversible inhibitors of bruton's tyrosine kinase (btk)
Inventor: CALDWELL RICHARD
IPC: A61K31/437
Filed: 2019-08-26
Abstract: The present invention relates to fused imidazo pyridine compounds of formula (I), and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.
Patent CA-3112649-A1 (CA)
Title: Porte d'acces pour utilisation possible avec un reservoir de carburant d'helicoptere
Inventor: SANNADI AMINE
IPC: B64C1/14
Filed: 2014-01-14
Abstract: Des systèmes pour des assemblages de portes d'accès améliorés sont décrits. Plus précisément, des assemblages de portes daccès sans boulon/vis comprenant un mécanisme de joint radial sont décrits. Selon certains modes de réalisation, lassemblage de porte daccès comprend un épaulement configuré pour résister aux contraintes intérieures et une bande de retenue configurée pour résister aux contraintes extérieures. Lassemblage de porte d'accès est aussi configuré pour souvrir lorsque la bande de retenue est retenue.
Patent CA-3116630-A1 (CA)
Title: Vecteurs viraux aav et leurs utilisations
Inventor: HATFIELD JAMES MICHAEL
IPC: C12N15/864
Filed: 2019-11-27
Abstract: L'invention concerne des compositions contenant des vecteurs viraux AAV9 et leurs procédés d'utilisation pour traiter des patients atteints d'une AMS, par exemple, des patients atteints d'une amyotrophie musculaire spinale (AMS) de type II et de type III.
Patent CA-3124512-A1 (CA)
Inventor: BENNETT JEFFREY
IPC: A61N1/36
Filed: 2020-01-10
Abstract: L'invention concerne un dispositif de neuromodulation et un procédé pouvant faire varier une thérapie de neuromodulation afin d'empêcher, de retarder ou de contrôler une émission sexuelle. Le dispositif peut utiliser le phénomène physiologique, chimique ou électrique détecté pour commander l'application de la thérapie.
Patent CA-3125701-A1 (CA)
Title: Mobile robot
Inventor: ZHANG JUNBIN
IPC: A47L11/40
Filed: 2019-09-29
Abstract: A mobile robot, comprising: a robot body (101), a drive wheel (1021), and at least two distance sensors (1033). The robot body (101) comprises a target side surface. The drive wheel (1021) is provided at the bottom of the robot body (101). The drive wheel (1021) is provided to drive the robot body (101) to move. The at least two distance sensors (1033) are sequentially provided at different positions on the robot body (101) along a forward movement direction of the mobile robot, thereby improving the accuracy of detecting, by a mobile robot having a non-cylindrical side surface, an obstacle located near the side surface of the mobile robot.
Patent CA-3127455-A1 (CA)
Title: Methods for mitigating liver injury and promoting liver hypertrophy, regeneration and cell engraftment in conjunction with radiation and/or radiomimetic treatments
Inventor: EICHENBAUM GARY
IPC: A61K35/407
Filed: 2020-01-24
Abstract: Methods and kits for mitigating liver injury and promoting liver regeneration and engraftment in a subject treated with a targeted radiation therapy are described. In particular, an effective amount of a thrombopoietin mimetic, such as RWJ-800088 or romiplostim, is used to mitigate the radiation-induced liver diseases and promote beneficial effects for liver regeneration and engraftment in conjunction with radiation or radiomimetics.
Patent CA-3127650-A1 (CA)
Title: Article container for an overhead conveying device and unloading station for unloading the same
Inventor: REISCHL JOSEF
IPC: B65G47/61
Filed: 2020-01-23
Abstract: The invention relates to a conveyed-goods container (2) for an overhead conveyor for transporting conveyed goods (4), said container comprising a pocket body which can be switched between a transport position and a loading and/or unloading position and which has: a front wall (30) and a rear wall (31) made of flexible material; a loading and/or unloading opening (34), at least regions of which are on a first side of the pocket body between the front and rear wall; and a side wall stop (46), at least regions of which are on a second side of the pocket body between the front and rear wall, and against which the conveyed goods can be placed. The front wall forms a first front wall section (35a) and a second front wall section (35b) and comprises a base plate (36) in the first front wall section (35a). The rear wall comprises a first rear wall section (45a) and a second rear wall section (45b). In the transport position of the pocket body, the first rear wall section forms a transport support (75) which slopes downwards in the direction of the side wall stop (46). The invention also relates to an unloading station for automatically unloading this conveyed-goods container.
Patent CA-3128815-A1 (CA)
Title: Vehicle brake control system and method
Inventor: POTTER WILLIAM JOHN
IPC: B60T13/66
Filed: 2021-08-24
Abstract: A brake control system includes one or more processors communicatively connected to at least one sensor configured to output at least one property measurement of air in a brake pipe of a vehicle braking assembly. The one or more processors are configured to determine, based on the at least one property measurement, a pressure reduction lower limit (PRLL) in the brake pipe. The one or more processors are further configured to control movement of a vehicle system that includes the brake pipe to enforce the PRLL by preventing a pressure reduction in the brake pipe that is less than the PRLL while one or more air reservoirs of the vehicle braking assembly are at a reduced charge state.
Patent CA-3128983-A1 (CA)
Inventor: ROTH DARIN L
IPC: H04N5/232
Filed: 2021-08-26
Abstract: A drawn agricultural implement includes a main frame and a plurality of ground engaging units supporting the main frame from a ground surface. A working unit is supported from the main frame and configured to engage crops as the implement moves in a forward direction across the ground surface. A draft tongue extends from the main frame for attachment to a tractor. A camera having a field of view is mounted on at least one of the draft tongue, the main frame and the working unit. The camera is movable relative to the at least one of the draft tongue, the main frame and the working unit to reposition the field of view.
Patent CA-3129792-A1 (CA)
Inventor: HAN LIN
IPC: G06Q40/00
Filed: 2021-09-02
Abstract: The present invention discloses a decentralized token swapping method with low slippage point and high liquidity. The present invention relates to the technical field of decentralized token exchanging, specifically, providing liquidity to a liquidity pool by a liquidity provider, depositing a X token and a Y token into the liquidity pool in an equal value ratio in a mortgage mode; providing liquidity to X maker pool and Y  Maker Pool by X maker and Y maker independently. In the present invention, a Taker determines to swap from the liquidity pool or the maker pools based on a random number. The present invention can effectively reduce the swapping slippage points:  if the leverage rate is n, then the slippage point can be reduced to 1/n of the Uniswap mode, and more demand can be provided. For instance, users who plan to sell one asset for another over a period of time can provide liquidity, rather than only rely on users in an equal ratio mortgage to provide liquidity.
Patent CA-3133193-A1 (CA)
Inventor: YAMADA MASAAKI
IPC: A61P9/10
Filed: 2020-03-04
Abstract: One aspect of the present invention is a gas product which comprises a gas container and a gas composition that is filled into the gas container, and which is configured such that: the gas composition contains nitrogen monoxide, hydrogen and an inert gas; and the concentration of the nitrogen monoxide is 20% by volume or less based on the volume of the gas composition.
Patent CA-3134829-A1 (CA)
Title: Vetements exterieurs de protection
Inventor: GABER JARED
IPC: A41D13/12
Filed: 2020-03-27
Abstract: La présente invention concerne des vêtements extérieurs de protection ainsi que des améliorations dans l'utilisation et la fabrication de ceux-ci. Les vêtements extérieurs de protection de l'invention peuvent comprendre une partie de protection avant intégrée ou reliée, sensiblement élastique et une barrière imperméable à l'humidité. La barrière imperméable à l'humidité peut avoir des manchons et s'étendre au-delà de la taille de l'enfant et au moins sur les épaules de l'utilisateur pour maintenir l'avant des vêtements de l'utilisateur propres et secs. La partie de protection avant sensiblement élastique peut comprendre un support, tel qu'un bavoir traditionnel, pour attraper et maintenir des aliments et des liquides lâchés ou répandus par le porteur pendant l'alimentation, la peinture, le bricolage, ou d'autres activités. Le porteur peut être un enfant, un bébé, une personne âgée, une personne en situation de handicap ou une personne ayant des besoins spéciaux, par exemple.
Patent CA-3138077-A1 (CA)
Title: Aube de turbomachine avec refroidissement ameliore
Inventor: OSTINO LEANDRE
IPC: F01D5/18
Filed: 2020-04-24
Abstract: L'invention concerne une aube de turbine comprenant un pied portant une pale terminée par un sommet en forme de baignoire, la pale comprenant une paroi d'intrados et une paroi d'extrados, ainsi qu'un bord d'attaque, un bord de fuite, et une paroi de sommet délimitant un fond de la baignoire, par lesquels la paroi d'intrados est reliée à la paroi d'extrados, cette pale comprenant également : un circuit médian (28) de type serpentin, incluant un premier conduit radial (41) collectant de l'air au niveau du pied et qui raccordé par un premier coude (46) à un deuxième conduit radial (42) qui est raccordé par un deuxième coude (47) à un troisième conduit radial (43); une cavité sous baignoire (36) longeant la paroi d'extrados (21) en s'étendant depuis une région centrale du sommet (S) jusqu'au bord de fuite (17); un conduit central (34) radial collectant de l'air au niveau du pied s'étendant entre au moins deux des trois conduits (41, 42, 43) du circuit médian (28) et alimentant directement la cavité sous baignoire (36).
Patent CA-3140618-A1 (CA)
Title: Method of oxidation in a molten salt bath
Inventor: TEDJAR FAROUK
IPC: C10B49/14
Filed: 2020-05-14
Abstract: The invention relates to a method for upgrading waste comprising organic components in a bath of molten salt(s), comprising the following steps: supplying (1) to a reactor, at least one salt or a mixture of salts comprising at least one alkali metal hydroxide; supplying (2) the waste to the reactor; heating (3) the reactor at a temperature above the melting point of the salt. Thus, the salt supplied melts to form a liquid reaction medium, and induce an at least partial oxidation (4) of the organic components. At least one compound resulting from this oxidation (4) is recovered (5). At least one alkali metal hydroxide comprises water of crystallization, acting as oxidizing agent for the organic components in the reaction medium, so as to participate in a production of dihydrogen, the latter being recovered (52) for the upgrading thereof.
Patent CA-3140953-A1 (CA)
Title: Dispositif d'ancrage pour fixer une ligne de securite a une barre de renforcement exposee au niveau d'un site de construction et procede associe
Inventor: MOOSE DARCY ROY
IPC: A62B1/18
Filed: 2020-06-12
Abstract: La présente invention concerne un dispositif de fixation à une barre de renforcement nervurée exposée au niveau d'un site de construction pour former un ancrage pour une ligne de sécurité comprenant un corps tubulaire définissant une cavité intérieure sensiblement cylindrique dimensionnée et façonnée de manière sensiblement correspondante à une longueur de la barre de renforcement de sorte que la cavité intérieure peut être reçue de manière ajustée sur la longueur de la barre de renforcement. Le dispositif comprend un emplacement de fixation défini sur le corps tubulaire pour relier la ligne de sécurité et comprend une pluralité de rainures définies au niveau de la cavité intérieure et agencées pour recevoir de manière adaptée des nervures de la barre de renforcement de façon à fixer le dispositif en un emplacement fixe le long de la barre de renforcement. Pendant la construction d'une structure, le dispositif est utilisé pour soutenir un travailleur contre la chute et peut ensuite être laissé attaché à la barre de renforcement et par la suite un reste de la structure peut être coulé dans le béton.
Patent CA-3143902-A1 (CA)
Title: Anti-cd24 antibody and uses thereof
Inventor: ARBER NADIR
IPC: A61K39/395
Filed: 2020-06-25
Abstract: An anti-CD24 antibody is provided. Accordingly, there is provided an antibody comprising an antigen recognition domain which specifically binds CD24 and comprises complementarity determining regions (CDRs) as set forth in SEQ ID NOs: 2, 3 and 4 arranged in a sequential order from N to C on a light chain of the antibody and CDRs as set forth in SEQ ID NOs: 6, 7 and 8 arranged in a sequential order from N to C on a heavy chain of said antibody. Also provided are polynucleotides encoding the antibody, host cells expressing the antibody the uses thereof.