baber/WOPTO huggingface dataset:
Patent AU-2018274874-A1 (AU)
Title: Methods of producing enriched populations of tumor reactive T cells from tumor
Inventor: ROSENBERG STEVEN A
IPC: C12N5/0783
Filed: 2018-12-04
Abstract: Methods of obtaining a cell population enriched for tumor-reactive T cells, the method comprising: (a) obtaining a bulk population of T cells from a tumor sample; (b) specifically selecting CD8* T cells that express any one or more of TIM-3, LAG-3, 4-1BB, and PD-I from the bulk population; and (c) separating the cells selected in (b) from unselected cells to obtain a cell population enriched for tumor-reactive T cells are disclosed. Related methods of administering a cell population enriched for tumor-reactive T cells to a mammal, methods of obtaining a pharmaceutical composition comprising a cell population enriched for tumor-reactive T cells, and isolated or purified cell populations are also disclosed.
Patent AU-2018283785-A1 (AU)
Title: Dynamic mold shape control for direct chill casting
Inventor: CORDILL CRAIG RICHARD
IPC: B22D11/055
Filed: 2018-06-11
Abstract: Provided herein is a system, apparatus, and method for continuous casting of metal, and more particularly, to a mechanism for controlling the shape of a direct chill casting mold to dynamically control a profile of an ingot cast from the mold during the casting process. Embodiments may provide an apparatus for casting material including: first and second opposing side walls; first and second end walls extending between the first and second side walls, where the first and second opposing side walls and the first and second opposing end walls form a generally rectangular shaped mold cavity. At least one of the first and second opposing side walls may include two or more contact regions, where each of the two or more contact regions may be configured to be displaced relative to a straight line along the side wall.
Patent AU-2018298059-A1 (AU)
Title: Data reconciliation based on computer analysis of data
Inventor: GORMAN KIERAN
IPC: G06Q20/38
Filed: 2018-07-03
Abstract: Methods, systems, and computer programs are presented for reconciling a transaction against data in a database to identify the transaction parameters based on text descriptors provided for the transaction. One method includes an operation for identifying features for reconciling transactions of a first entity by a machine-learning program. The features include, at least, a description of the transaction, a name of a second entity in the transaction, a location of the second entity, and an account for the transaction. The machine-learning program is trained with training data that includes values of the features for previously reconciled transactions. A received first transaction includes a description, a date, and an amount. The first transaction is input for the machine-learning program, which generates one or more suggestions for reconciling the first transaction. Each suggestion includes the name of the second entity in the first transaction and an account.
Patent AU-2018301393-A1 (AU)
Title: Agonist antibodies that bind human CD137 and uses thereof
Inventor: BOBROWICZ PIOTR
IPC: C07K16/28
Filed: 2018-07-11
Abstract: The present disclosure relates to,
Patent AU-2018311081-A1 (AU)
Title: Needle and catheter insertion device
Inventor: ISAACSON SHAWN RAY
IPC: A61M5/158
Filed: 2018-08-03
Abstract: A needle (26) is provided that can be used for introducing or aspirating fluids to a patient or as an introducer needle for positioning and inserting a catheter (58), such as a peripheral IV catheter into a patient. The needle (26) can be an introducer needle that extends from the distal end of the catheter during insertion. The needle (26) has an insertion tip with a configuration to assist penetration into a vein (60) with a reduced incidence of injuring the inner surface of the vein or inadvertently passing through side wall of the vein. The needle tip (46) can be formed with a curved distal end surface (54) where the pointed tip (46) is spaced radially inward relative to the outer surface (56) of the needle (26). In another embodiment the needle tip can have a reverse beveled surface (42, 44) having an axial length, angle, and curvature to assist in penetrating the vein with a reduced incidence of transfixing the vein.
Patent AU-2018314562-A1 (AU)
Title: Herbicidal mixtures comprising L-glufosinate or its salt and at least one VLCFA inhibitor
Inventor: WINTER CHRISTIAN HARALD
IPC: A01N43/10
Filed: 2018-08-02
Abstract: The present invention relates to herbicidal mixture comprising L-glufosinate or its salt and at least one VLCFA inhibitor. The invention furthermore relates to a method for controlling undesirable vegetation in burndown programs, in industrial vegetation management and forestry, in vegetable and perennial crops and in turf and lawn.
Patent AU-2018326596-A1 (AU)
Title: High concentration dosage forms of pridopidine
Inventor: LICHT DANIT
IPC: A61K31/451
Filed: 2018-08-30
Abstract: The subject invention provides a solid unit dosage form comprising pridopidine and at least one pharmaceutically acceptable excipient, wherein the dosage form has a volume and wherein the ratio of the amount of pridopidine to the volume of the dosage form is 135-600 mg/ml.
Patent AU-2018333861-A1 (AU)
Title: Method of and apparatus for inspecting a ferromagnetic object
Inventor: BLUM DIETER WOLFGANG
IPC: G01M17/013
Filed: 2018-08-29
Abstract: A method of inspecting a ferromagnetic object includes positioning a plurality of magnetic field sensors proximate the ferromagnetic object and when a plurality of magnetic field sensors sense respective magnetic field values at respective different locations proximate at least one surface of the ferromagnetic object, causing the plurality of magnetic field sensors to generally traverse around the ferromagnetic object.
Patent AU-2018351989-A1 (AU)
Title: Data routing in communications systems
Inventor: KAPELA ANTON L
IPC: H04W8/08
Filed: 2018-10-09
Abstract: A method, a system, and a computer program product for data routing in communications systems. A data packet is received and source of the data packet is determined, based on the source of the data packet, a forwarding route for transmission of the data packet is determined. The forwarding route includes at least one of the following: a known content route and a default content route. The data packet is transmitted based on the determined forwarding route.
Patent AU-2018377716-A1 (AU)
Title: Nucleic acid, composition and conjugate containing same, and preparation method and use
Inventor: ZHANG HONGYAN
IPC: A61K48/00
Filed: 2018-11-29
Abstract: Provided are a siRNA for suppressing hepatitis B virus gene expression, and a pharmaceutical composition and conjugate containing the siRNA. Each nucleotide in the siRNA is an independent modified nucleotide. The siRNA contains a positive-sense strand and an antisense strand. The positive-sense strand of the siRNA contains a nucleotide sequence 1 having an equal length to a nucleotide sequence shown in SEQ ID NO: 155 with no more than three nucleotide differences, and the antisense strand of the siRNA contains a nucleotide sequence 2 having an equal length to a nucleotide sequence shown in SEQ ID NO: 156 with no more than three nucleotide differences.
Patent AU-2018381093-A1 (AU)
Title: Methods and systems for evaluating compliance of communication of a dispatcher
Inventor: HO SHYAN JENQ
IPC: G16H80/00
Filed: 2018-11-19
Abstract: Methods and systems for evaluating compliance of communication of a dispatcher. One system (100) includes an electronic computing device that includes an input device (206), a transceiver (136), and one or more electronic processors. The one or more electronic processors are configured to monitor communication between a dispatcher and a caller during a call and determine a type of call. The one or more electronic processors are further configured to determine a conversational procedure based on the type of call and compare a characteristic of the monitored communication to a constraint of the conversational procedure. The one or more electronic processors are further configured to determine that the characteristic of the monitored communication is outside the constraint of the conversational procedure and take an action as a function of determining that the characteristic of the monitored communication is outside the constraint of the conversational procedure.
Patent AU-2018390924-A1 (AU)
Title: Gender specific synthetic nutritional compositions comprising lycopene and nutritional systems comprising them
Inventor: THAKKAR SAGAR
IPC: A23L33/10
Filed: 2018-12-20
Abstract: Gender specific synthetic nutritional compositions comprising lycopene in concentrations reflecting those found in human milk produced by mothers of infants of the corresponding gender at the corresponding stage of lactation, and nutritional systems comprising them.
Patent AU-2018391217-A1 (AU)
Title: LAG-3 antibody pharmaceutical composition and use thereof
Inventor: WU TINGTING
IPC: A61P35/00
Filed: 2018-12-21
Abstract: Disclosed are a lymphocyte-activation gene 3 (LAG-3) antibody pharmaceutical composition and the use thereof. The pharmaceutical composition comprises a LAG-3 antibody or an antigen-binding fragment thereof in an acetate buffer or in a histidine salt buffer. The pharmaceutical composition may also comprise sugar, non-ionic surfactant and other excipients.
Patent AU-2018443181-A1 (AU)
Title: Gate driving circuit, method for controlling gate driving circuit, and mobile terminal
Inventor: LIU CHUN YEN
IPC: G09G3/36
Filed: 2018-09-28
Abstract: A gate drive circuit (01) and control method therefor, and a mobile terminal, relating to the technical field of display, for solving the problem that a complete image cannot be displayed after a flexible display screen is folded. The gate drive circuit (01) comprises a first drive group (11_A), a first connection controller (12_B), and a second drive group (11_B). The first drive group (11_A) is used for receiving a starting signal (STV) output by a first signal end ((1)) of a display driver (DDIC). A first end of the first connection controller (12_B) is used for receiving an effective signal output by the first drive group (11_A). A second end of the first connection controller (12_B) is used for receiving a cascade gating signal (Sel1) output by a second signal end ((2)) of the display driver (DDIC). A third end of the first connection controller (12_B) is used for receiving a split-screen gating signal (Sel2) output by a third signal end ((3)) of the display driver (DDIC). A fourth end of the first connection controller (12_B) is used for receiving a split-screen display signal (STV_d) output by a fourth signal end ((4)) of the display driver (DDIC). The second drive group (11_B) is used for receiving an effective signal output by a fifth end of the first connection controller (12_B).
Patent WO-2019173866-A1 (WO)
Title: Sensory stimulation apparatus
Inventor: AGNIHOTRI VIRAJ
IPC: A61N2/02
Filed: 2019-03-12
Abstract: Apparatus for providing sensory stimulation to a subject, the apparatus including an input that acquires input signals indicative of a stimulatory input, a signal generator, a coil system including at least one coil and an electronic controller operating in accordance with software instructions. In use, the controller receives the input signals from the input, performs analysis of the input signals and, uses results of the analysis to cause the signal generator to generate stimulation signals, the stimulation signals being applied to the coil system to thereby generate a stimulatory electromagnetic field in a target region of the subject, the stimulatory electromagnetic field being configured to selectively activate sensory neurons to thereby stimulate the subject in accordance with the stimulatory input.
Patent WO-2020047604-A1 (WO)
Title: Biomarkers for cancer therapy
Inventor: LEE JASON
IPC: C12Q1/6886
Filed: 2019-09-06
Abstract: This invention relates generally to biomarkers that are useful for determining whether a subject with cancer is likely to respond to cancer therapy. The invention therefore relates to methods, kits and compositions for determining whether a subject is likely to respond to cancer therapy, and to methods of treatment based on a determination that a subject with cancer is likely to respond to cancer therapy. The invention also relates to methods for sensitizing a subject with cancer to cancer therapy.
Patent AU-2019203051-A1 (AU)
Title: Suspensions of cyclosporin A Form 2
Inventor: GORE ANURADHA V
IPC: A61K9/00
Filed: 2019-04-30
Abstract: SUSPENSIONS OF CYCLOSPORIN A FORM Disclosed herein are methods of making suspensions of cyclosporin A Form. 2.
Patent AU-2019204106-A1 (AU)
Title: Intraocular drug delivery device and associated methods
Inventor: AMBATI BALAMURALI K
IPC: A61P27/02
Filed: 2019-06-12
Abstract: INTRAOCULAR DRUG DELIVERY DEVICE AND ASSOCIATED METHODS OF THE INVENTION Devices, systems, and methods for delivery of an active agent into the eye of a subject can include an intraocular active agent delivery device including an active agent dispersed within a biodegradable active agent matrix. The active agent includes dexamethasone and the delivery device is adapted to fit within a lens capsule or ciliary sulcus of an eye. The delivery device can be inserted into the lens capsule or ciliary sulcus of an eye during cataract surgery or for treatment of uveitis.
Patent AU-2019219830-A1 (AU)
Title: Fully integrated, disposable tissue visualization device
Inventor: DAVISON ANDREW C
IPC: A61B1/04
Filed: 2019-08-23
Abstract: FULLY INTEGRATED, DISPOSABLE TISSUE VISUALIZATION DEVICE The present invention relates to a fully integrated sterilizable one time use disposable tissue visualization device and methods for using such devices. Preferred embodiments of the invention facilitate the visualization of an internal tissue site while causing a minimum of damage to the surrounding tissue. Further preferred embodiments may allow for the delivery of fluids and other treatment to an internal tissue site. -61 11399717_1 (GHMatters) P108142.AU.1
Patent AU-2019226215-A1 (AU)
Title: Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases
Inventor: VISWANATH VEENA
IPC: A61K9/00
Filed: 2019-09-06
Abstract: USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES Abstract The present invention relates to a method for treating ocular inflammatory diseases in a subject in need of such treatment, which comprises administering a pharmaceutical composition comprising a therapeutically effective amount of at least one agonist of Formyl peptide receptor 2.
Patent AU-2019229426-A1 (AU)
Title: Spring Loaded Quick Release System
Inventor: TODD ETHAN
IPC: F41A23/08
Filed: 2019-09-13
Abstract: Abstract The invention relates to a quick release mechanism that allows two separate components to be connected together and disconnected from each other easily. Once connected the two components are held together firmly by forces generated by the spring of the system. Whilst connected, rotation and pivoting are still possible. The system of quick release is especially useful for attaching a gun to a bi-pod. However other devices or components may be attached to a bi-pod such as a camera for example. The quick release mechanism is also useful for attaching components to a tri-pod. 6 of 11 Figure 8 Fg4 Figure 9
Patent AU-2019240176-A1 (AU)
Title: Wear-levelling apparatus for cyclones
Inventor: SWINTAK MIKE
IPC: B04C5/085
Filed: 2019-03-13
Abstract: A wear-levelling apparatus (124) for a cyclone (100) includes: an upper section (128) defining an upper portion of a frusto-conical channel configured to receive material for delivery to a lower portion of the channel; a bearing assembly connected to the upper section; and a lower section (132) coupled to the upper section by the bearing assembly to permit rotation of the lower section about an axis of the channel; the lower section defining a lower portion of the channel configured to receive the material from the upper portion for discharge toward an outlet (120) of the cyclone.
Patent AU-2019261735-A1 (AU)
Title: System and method for recommending automation solutions for technology infrastructure issues
Inventor: BALASUBRAMANIAN RAMKUMAR
IPC: G06Q10/06
Filed: 2019-11-06
Abstract: A system and method to intelligently formulate automation strategies for technology infrastructure operations are disclosed. The system and method include analyzing infrastructure issue data from support tickets and predicting automation solutions. A cost benefit analysis is then performed on the automation solutions. Solutions can be ranked and recommended according to the cost-benefit analysis. RECEIVE SUPPORT TICKETS AND EXTRACT INFRASTRUCTURE ISSUE DATA 100 ANALYZE 102 INFRASTRUCTURE DETERMINE ISSUES THAT CAN BE SOLVED 104 BY AUTOMATION PREDICT AUTOMATION 106 SOLUTIONS FOR ISSUES THAT CAN BE AUTOMATED PERFORM COST BENEFITANALYSIS 108 RANK AND/OR RECOMMEND AUTOMATION 110 SOLUTIONS ACCORDING TO COST-BENEFIT ANALYSIS
Patent AU-2019289217-A1 (AU)
Title: Bridged compounds as agonists of the muscarinic M1 and/or M4 receptor
Inventor: BROWN GILES ALBERT
IPC: A61P25/28
Filed: 2019-06-24
Abstract: This invention relates to compounds that are agonists of the muscarinic M
Patent AU-2019296526-A1 (AU)
Title: Substituted-N-heteroaryl compounds and uses thereof
Inventor: TOOP HAMISH
IPC: A61P25/08
Filed: 2019-10-30
Abstract: The present disclosure relates generally to compounds useful for the treatment and/or enhancement of cognitive function and negative symptoms associated with central nervous system disorders where the circuitry involving fast spiking PV+ interneurons and the production of cortical gamma oscillations is disrupted. The subject disclosure enables the manufacture of medicaments as well as compositions containing same for use in methods of therapy and prophylaxis of cognitive dysfunction and negative symptoms.
Patent AU-2019325969-A1 (AU)
Title: Inverter topology
Inventor: KHALIL AHMED
IPC: H02M7/5387
Filed: 2019-08-12
Abstract: An electrical inverter may include a plurality of phase modules to provide a plurality of phase outputs. Two or more of the plurality of phase modules may share a common insulated-gate bipolar transistor.
Patent AU-2019330385-A1 (AU)
Title: Hardening method and apparatus, particularly applicable to metal and/or ceramics
Inventor: BEN-ZUR OFER
IPC: B33Y30/00
Filed: 2019-08-27
Abstract: Apparatus and method for hardening a paste within walls of a mold, comprises a sealing hood that opens to a first position allowing paste to be applied within the mold and then closes to provide an airtight seal around the mold and the paste applied within the mold. Then a vacuum source evacuates air from the sealing hood in its closed position to apply a vacuum to the paste. The vacuum causes liquids to evaporate from the paste, and thus hardens the paste.
Patent AU-2019366449-A1 (AU)
Title: Natural sweetening flavor composition
Inventor: HOFMEKLER ORI
IPC: A23L27/30
Filed: 2019-10-25
Abstract: The present invention is directed to high potency sweeteners having at least one sweetening agent and at least one flavorant, wherein the sweetening agent is present in an amount of about 80% to about 97% by weight of the composition and the flavorant is present in an amount of about 3% to about 20% by weight of composition. The invention is also directed to sugar substitute compositions having resistant dextrin fiber, at least one sweetening agent, at least one flavorant, and processed rice extract.
Patent AU-2019370159-A1 (AU)
Title: Drug delivery devices with partial drug delivery member retraction
Inventor: NEKOUZADEH ALI
IPC: A61M5/158
Filed: 2019-10-14
Abstract: Methods, devices, and components are provided to reduce tissue resistive pressure during a subcutaneous drug delivery operation by increasing the size of the injection cavity by partially retracting the drug delivery member after inserting the drug delivery member to a subcutaneous position. The drug delivery devices described herein include a motor operably coupled to a drug delivery member. The motor can be selectively activated by a controller to retract the drug delivery member a predetermined distance to relieve pressure in an injection cavity in a patient. A force sensor can provide the controller with a drug delivery member insertion force. The controller can then estimate a tissue resistive pressure based on the drug delivery member insertion force and determine the predetermined distance for the partial drug delivery member retraction based on the tissue resistive pressure.
Patent AU-2019370929-A1 (AU)
Title: Agricultural baler with density doors moved by dual acting fluid cylinders
Inventor: MONBALIU SVEN
IPC: A01F15/08
Filed: 2019-10-30
Abstract: An agricultural vehicle (10) comprising a bale chamber (26) includes: a plurality of movable density doors (210A, 210B, 210C); at least one fluid cylinder (220A, 220B) including a fluid chamber (322A, 322B), a piston (323A, 323B) disposed in the fluid chamber (322A, 322B) to separate the fluid chamber (322A, 322B) into a piston side (324A, 324B) and a rod side (325A, 325B), and a cylinder rod (221A, 221B) coupled to the piston (323A, 323B) on the rod side (325A, 325B) and configured to move at least one of the density doors (210A, 210B, 210C); and a fluid supply circuit (300) fluidly coupled to the fluid chamber (322A, 322B) and configured to supply working fluid to the fluid chamber (322A, 322B); wherein the at least one fluid cylinder (220A, 220B) further includes a piston fluid port (326A, 326B) that fluidly couples the piston side (324A, 324B) of the fluid chamber (322A, 322B) to the fluid supply circuit (300) and a rod fluid port (327A, 327B) that fluidly couples the rod side (325A, 325B) of the fluid chamber (322A, 322B) to the fluid supply circuit (300); and the fluid supply circuit (300) further includes a fluid supply controller (310) that is selectively switchable to a first fluid supply mode and a second fluid supply mode, the fluid supply circuit (300) being configured to supply working fluid to only the piston side (324A, 324B) of the fluid chamber (322A, 322B) when the fluid supply controller (310) is in the first fluid supply mode and to supply working fluid to both the piston side (324A, 324B) and the rod side (325A, 325B) of the fluid chamber (322A, 322B) when the fluid supply controller (310) is in the second fluid supply mode.
Patent AU-2019374098-A1 (AU)
Title: Polymerases, compositions, and methods of use
Inventor: GOLYNSKIY MISHA
IPC: C12Q1/6844
Filed: 2019-10-31
Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain high fidelity under reduced incorporation times, as well as methods and kits using the same.
Patent AU-2019376006-A1 (AU)
Title: Cationic lipids containing silicon
Inventor: ABRAMS MICHAEL J
IPC: C12N15/113
Filed: 2019-11-08
Abstract: Certain embodiments of the invention provide a cationic lipid of formula (I): wherein R
Patent AU-2019394365-A1 (AU)
Title: Novel composition
Inventor: DE NYS ROCKY
IPC: A61K36/04
Filed: 2019-12-06
Abstract: The field of the invention relates to processes for preparing