baber/WOPTO huggingface dataset:
Patent PT-874645-E (PT)
Inventor: FRENZEL THOMAS
IPC: A61K49/00
Filed: 1997-01-16
Abstract: The invention relates to new, monomeric, perfluoroalkyl-substituted metal complexes, processes for their production, and their use in diagnosis and therapy. The compounds according to the invention are suitable especially as in vivo contrast media in nuclear spin tomography (MRT). They can preferably be used as blood-pool agents and as lymphographic agents.
Patent PT-1009687-E (PT)
Inventor: OLSON AKE
IPC: B65D77/06
Filed: 1997-02-14
Abstract: PCT No. PCT/SE97/00250 Sec. 371 Date Sep. 15, 1998 Sec. 102(e) Date Sep. 15, 1998 PCT Filed Feb. 14, 1997 PCT Pub. No. WO97/34794 PCT Pub. Date Sep. 25, 1997A liner (1) intended as inner packing in a container (11) for holding a fluid, comprising an upper (2) and a lower (3) rectangular web of essentially the same length and width, which are made of a flexible material and which are joined (4) to each other along portions of their outer edges (8, 9, 34), and at least one sealable opening (5, 6) in one of the webs (3) for filling the liner (1) with said fluid and then emptying the liner of said fluid in the container (11). The novelty of the invention is that the liner integrally comprises a pair of flap members (41, 42) at one of the outer edges (33) between the webs (2, 3), that one flap member (41) has been folded over the upper web (2), that the corner portions (13) of the liner adjacent to the essentially unfolded flap member (42) have been folded towards the center over the upper web (2), and that the liner (1) has been folded symmetrically at least twice towards the symmetry line (7) over the upper web (2). The invention also relates to the use of the liner with a container.
Patent PT-941227-E (PT)
Inventor: REICHENBACH HANS
IPC: C07D493/04
Filed: 1997-11-18
Abstract: Epothilone derivatives are obtained by: (1) cultivation of Sorangium cellulosum DSM 6773 in the presence of an absorption resin; (2) separation of the resin and culture followed by washing with aqueous methanol; (3) eluting the washed resin with methanol and reducing the extract; (4) partitioning the extract between methanol and hexane; (5) reducing the methanolic phase and fractionating it on a Sephadex column, and (6) isolation of the epothilones by chromatography using a methanol/water mixture. Epothilone A is followed by epothilone B, and two further fractions.
Patent PT-930092-E (PT)
Inventor: IRSCH HANS-PETER
IPC: B01F7/00
Filed: 1998-12-16
Abstract: The apparatus is divided into two separately movable units (1, 2).
Patent PT-1025309-E (PT)
Inventor: MARCHAL PAUL
IPC: B08B1/00
Filed: 1998-01-30
Abstract: A dust and fiber control device for paper making apparatus is described. The device includes a wall in conjunction with a feed spout for providing a water curtain. The water curtain serves to capture and remove air suspended dust and fiber particles from ambient air. The device is positioned transversely to the motion of a paper web underneath the web between a drying cylinder and a rewinder. The water curtain device is utilized in conjunction with air flow devices for assisting in controlling the collection of air suspended dust and fiber particles from the ambient air.
Patent PT-981525-E (PT)
Inventor: HEYMES ALAIN
IPC: C07D495/04
Filed: 1998-05-11
Abstract: A process for the preparation of [2-(2-thienyl)-ethylamino]-(2-halogenophenyl)-acetonitriles of general formula (I) starting from 2-(2-thienyl)-ethyl-amine, alkalicyanide and o-halogeno-benzaldehyde. Compounds of general formula (I) are valuable intermediates.
Patent PT-1007685-E (PT)
Inventor: BIRKELUND SVEND
IPC: A61K39/00
Filed: 1998-06-19
Abstract: The invention relates to the identification of members of a gene family from the human respiratory pathogen Chlamydia pneumoniae, encoding surface exposed membrane proteins of a size of approximately 89-101 kDa, preferably about 89.6-100.3 kDa and about 56.1 kDa. The invention relates to the novel DNA sequences, the deduced amino acid sequences of the corresponding proteins and the use of the DNA sequences and the proteins in diagnosis of infections caused by C. pneumoniae, in pathology, in epidemiology, and as vaccine components.
Patent PT-965615-E (PT)
Inventor: BASTIOLI CATIA
IPC: B29C47/00
Filed: 1999-06-17
Abstract: Heterophasic compositions comprising starch and a thermoplastic polymer that is incompatible with the starch, in which the starch constitutes the discontinuous phase and the thermoplastic polymer the continuous matrix, having an impact strength greater than 30 KJ/m2 (measured on blown film of 30 microns thick at 10 DEG C and RH less than 5%), and further characterised by the presence in the X-ray diffraction spectrum of a peak at an angle 2-theta from 13 to 14 DEG the ratio of the intensity of which to that of the peak of the amorphous starch which occurs at 20.5 DEG , is less than 2 and greater than 0.02. <IMAGE>
Patent PT-1054686-E (PT)
Inventor: BEIJNEN JACOB HENDRIK
IPC: A61P35/00
Filed: 1999-02-18
Abstract: A stable pharmaceutical composition of a didemnin compound, comprises firstly a lyophilized didemnin preparation including water-soluble material and secondly a reconstitution solution of mixed solvents.
Patent PT-1075262-E (PT)
Inventor: YELLE WILLIAM E
IPC: C07D401/12
Filed: 1999-05-05
Abstract: Methods and compositions are disclosed utilizing desmethylpantoprazole for the treatment of ulcers in humans. Desmethylpantoprazole exhibits a lessened liability toward drug-drug interactions than pantoprazole and a more predictable dosing regimen than pantoprazole. Desmethylpantoprazole is also useful for the treatment of gastroesophageal reflux and other conditions related to gastric hypersecretion such as Zollinger-Ellison Syndrome.
Patent PT-1119596-E (PT)
Inventor: SARTORI GUIDO
IPC: C23F15/00
Filed: 1999-09-24
Abstract: The present invention relates to a process for reducing the acidity of a petroleum oil containing organic acids comprising treating said petroleum oil containing organic acids with an effective amount of an alcohol at a temperature and under conditions sufficient to form the corresponding ester of said alcohol and wherein said treatment is conducted in the presence of a metal carboxylate.
Patent PT-1084147-E (PT)
Inventor: INGA LAURSEN
IPC: C07K1/18
Filed: 1999-06-09
Abstract: The present invention relates to a process for purifying immunoglobulin G from a crude immunoglobulin-containing plasma protein fraction. Said process includes a number of steps, wherein the buffer used for the anion exchange chromatography and the cation exchange chromatography is preferably the same buffer. An acetate buffer having a pH of about 5.0-6.0 and having a molarity of about 5-25 mM is preferably used throughout the purification process. The invention further comprises an immunoglobulin product, which is obtainable by this process. The invention also relates to an immunoglobulin product which has a purity of more than 98%, has a content of IgG monomers and dimers of more than 98.5%, has a content of IgA less than 4 mg of IgA/I, and contains less than 0.5% polymers and aggregates. Said product does not comprise detergent, PEG or albumin as a stabilizer. The product is stable, virus-safe, liquid and ready for instant intravenous administration.
Patent CA-2086730-F (CA)
Title: Heat exchange element
Inventor: CROSSLEY JULIAN GARATH
IPC: F28D1/04
Filed: 1993-01-05
Granted: 1993-07-09
Abstract: A  method  of  manufacturing  a  removable  heat exchange element for a heat exchanger e.g.  a cooling radiator for a car, comprises taking a length of tubing which has  been preformed  to have an accurately flat surface and bonding a fin to the surface.  Preferably the tubing has been precoated with a metallic bonding agent such as solder or brazing alloy and the bonding includes heating the tubing and fin to melt the solder or alloy, and then cooling the assembly.
Patent SG-66685-G (SG)
Title: Shape selective acid catalyzed reactions of olefins over crystalline zeolites
IPC: C07C13/28
Filed: 1985-09-09
Abstract: Processes are provided for conducting selective acid catalyzed reactions involving olefins. Said catalytic reactions comprise isomerization, alkylation, addition, oligomerization, polymerization, aromatization, cracking and hydrocracking. The useful catalysts of this invention are the acidic forms of a novel class of zeolites characterized by a silica to alumina mole ratio of at least 12 and a constraint index in the approximate range of greater than about 2 to about 12. By utilization of such zeolites, smaller olefins are preferentially reacted when in mixed streams with larger olefins. Further of the such smaller olefins, linear olefins are preferentially reacted when in mixed streams with non-linear olefins and lesser branched olefins are preferentially reacted when in mixed streams with more highly branched olefins. Over the novel catalysts of this invention, para-disubstituted and/or mono-substituted aromatic olefins will react preferentially over ortho- and/or meta-disubstituted or more highly substituted aromatic olefins.
Patent IE-33059-L (IE)
Title: Data transmission system
IPC: H04B14/02
Filed: 1969-04-17
Abstract: 1,257,308. Multiplex radio signalling. GENERAL ELECTRIC CO. Ltd. 17 April, 1969 [17 April, 1968], No. 18129/68. Heading H4L. In a signalling system in which data is transmitted by phase modulation of a carrier wave, an auxiliary or supervisory signal is-transmitted by frequency modulation of said carrier, the highest frequency component of the -auxiliary signal being of lower frequency than the data bit rate, such that the maximum phase shift of the carrier due to the frequency modulation during any one pulse interval of the data transmission is much less than the minimum step phase shift utilized in transmitting the data. Transmitter, Fig. 2.-Data signals in dibit form, from sources 5 are modulated on to four carrier waves by respective phase modulators 4 providing four -possible phase shifts of -the carrier, the carriers being derived from sources 6 via frequency-modulators 7 and filters 8. Auxiliary signals from sources 9 are supplied to the modulators 7 so that one auxiliary signal is modulated on each carrier. Alternatively one auxiliary signal may be transmitted as a differential modulation of a pair of carriers. The outputs of the phase modulators 4 are supplied via filters 10 to an amplifier 11 where they are combined for transmission by radio. Repeater, Fig. 3.-Each aerial 12 is arranged to receive -and transmit both vertical -and horizontally polarized signals so that each repeater can transmit and receive two groups of four carrier frequencies in either direction. Received signals are supplied via a circulator 13 and filter 14 to a mixer 15, the output of the mixer 15 being supplied via an I.F. amplifier to a mixer 17 providing a signal for retransmission via filter 21, amplifier 22 and circulator 23. An oscillator 18 provides local oscillations for the mixer 17 and after mixing at 19 with output of an oscillator 24 provides local oscillations for the mixer 20. An auxiliary signal may be transmitted to the terminal station by frequency modulating the output of oscillator 24 so that it is modulated on all four carriers. Receiver, Fig. 4.-The auxiliary signals are recovered frequency-multiplying all the carrier signals by four so that the phase-shifts representing the data signals become multiples of a complete cycle and have no effect. The resulting signals are supplied via filters 26 to frequency dividers 27 where the original carrier frequencies, modulated in frequency but without the phase shift modulation, are recovered and are supplied to control the frequency of oscillators 28. Low frequency signals carrying the frequency modulation may be derived by mixing the output of each oscillator 28 with unmodulated carrier signals or in the case of differentially modulated carriers by supplying the differentially modulated carriers to a mixer 33 and applying the output of the mixer to a frequency discriminator 34. Synchronous detectors 29 recover the data signals which are regenerated at 30 and separated into individual pulse trains at 31.
[GB1257308A]
Patent IE-840590-L (IE)
Title: Calibration warning apparatus
IPC: G01K3/04
Filed: 1984-03-09
Abstract: A circuit for indicating when recalibration of an electrical sensor is necessary includes an analog driving circuit adapted to be coupled to the sensor, and an analog indicating device coupled to the analog driving circuit for indicating when the sensor should be recalibrated. The analog driving circuit provides a signal proportional to the current received from the electrical circuit. The indicating device is responsive to the output from the analog driving circuit and provides an output which is a function of both the sensor output and the elapsed time that the sensor has been operated.
[US4721942A]
Patent IE-890687-L (IE)
Title: Porphyrins and cancer treatment
IPC: C07D487/22
Filed: 1989-03-02
Abstract: This invention provides novel compounds for therapy of tumours suceptible to necrosis when an appropriate compound is adminstered followed by illumination with light of a wavelength absorbed by the compound, the compounds being dihydro porphyrins of the formula, or the corresponding tetra-hydro porphyrins: <CHEM> where n = 1 to 3 and each substituent R, the same or different and at the same or different position in its respective substituent phenyl ring, is an hydroxy group.
Patent IE-800845-L (IE)
Title: Electronically controlled franking machine
IPC: G06F12/16
Filed: 1980-04-25
Abstract: Electronic control for franking machines such as postage meters and stamping machines having a printing device, a postage value printing selection device, a total postal charge storage register and a settable subtracting value counter, including a microprocessor, a volatile main memory for storing data and non-volatilesemiconductor memories for storing data and the number of writing cycles performed, the memories being connected to the microprocessor, a line voltage power supply, supply capacitors disposed in the power supply, a switch controlled by the microprocessor for connecting the non-volatile memories to the supply capacitors of the power supply exclusively in the event of an interruption of the line voltage to cause the non-volatile memories to take over data stored in the main memory, and a register connected to one of the non-volatile memories for preventing the exceeding of a predetermined number of writing cycles of the one non-volatile memory after the power supply resumes.
[US4335434A]
Patent IE-45139-L (IE)
Title: Extraction of timing information from digital signalling¹systems
IPC: E21B47/18
Filed: 1977-04-28
Abstract: The disclosure relates to a technique for receiving a carrier signal modulated with digital symbols, the symbol rate being related to the carrier frequency, such as by a submultiple or a ratio of integers. An adaptive carrier-aided symbol tracking loop is provided in which signals derived from a symbol-coherent carrier maintain and aid symbol synchronization during periods of no symbol transitions.
[CA1119686A]
Patent FI-830293-L (FI)
Inventor: HAMMOND MICHAEL DOUGLAS
IPC: G01N33/86
Filed: 1983-01-27
Abstract: A method for determining allergenic sensitivity of a mammal is disclosed. The method involves measuring the time required for hemostasis of a blood sample with an allergen in the presence of a blood clotting inhibitor and comparing the time required for hemostasis in the presence of a blood clotting inhibitor and the absence of the allergen. The sensitivity to the allergen is determined by determining the difference in time required for hemostasis.
Patent IE-801162-L (IE)
Title: Pharmaceutical compositions
IPC: C07D233/70
Filed: 1980-06-05
Abstract: A compound for the alleviation of hypotension or the treatment of cardiac failure, having the formula <IMAGE> wherein R is hydrogen, C1-4 alkyl, (C1-4 alkyl) carbonyl or benzoyl; R1 is hydrogen or C1-4 alkyl; and Ar is 2-furyl; 2-thienyl; phenyl; phenyl monosubstituted by halogen, hydroxy, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, trifluoromethyl, -SO2N(R2)2, NR3R4, pyrrolidino, piperidino, morpholino, piperazino or N'-alkylpiperazino in which R2, R3 and R4 are independently selected from hydrogen and C1-4 alkyl; disubstituted phenyl in which one substituent is at the para position and the substituents are independently selected from halogen, hydroxy, C1-4 alkyl and C1-4 alkoxy; or 3,4-methylenedioxy- phenyl in which the methylene group is optionally substituted by one or two methyl groups; or a pharmaceutically acceptable salt thereof. Many compounds of formula I are novel.
[GB2055364A]
Patent IE-881273-L (IE)
Title: Monoclonal antibodies
IPC: C12N5/10
Filed: 1988-04-28
Abstract: A hybrid cell line capable of producing monoclonal antibodies uniquely specific to human neutrophils and eosinophils and exhibiting no specificity for lymphocytes, basophils and monocytes. Further there is noreactivity with acute leukemia cells. One of the partners in the hybridoma fusion of a mouse spleen cell developed from using human granulocytes as the immunization agent. The monoclonal antibody further is capable of being used to enumerate and isolate neutrophils in normal peripheral blood and possibly in blood of patients with acute leukemia.
[US4865971A]
Patent IE-45532-L (IE)
Title: Isoxazolylmethylthio carbamates
IPC: A01N47/12
Filed: 1977-07-22
Abstract: Novel isoxazolylmethyl thiocarbamates of the formula I are used for controlling undesired plant growth either by themselves or together with a carrier. The symbols in formula I have the meaning given in Patent Claim 1. <IMAGE>
[GB1581767A]
Patent IE-781811-L (IE)
Title: N-substituted-6-oxamorphinans
IPC: C07D491/08
Filed: 1978-09-07
Abstract: N-substituted 6-oxamorphinans have been found to possess potent analgetic, narcotic antagonist, antitussive, and ADH inhibitory activity. A particularly preferred compound is (-)-17-cyclopropylmethyl-3-hydroxy-6-oxamorphinan. The compounds are prepared by total synthesis and are not derived from opium alkaloids.
[US4154932A]
Patent IE-862019-L (IE)
Title: Pyrrolidinyl-dihydroquinolines
IPC: C07D401/04
Filed: 1986-07-29
Abstract: A method for the treatment and/or prophylaxis of cerebrovascular disorders and/or disorders associated with cerebral senility in mammals, such as humans, which comprises administering to the mammal in need of such treatment and/or prophylaxis an effective and/or prophylactic amount of a compound of formula (I): <CHEM> wherein: n is 1 or 2; R1 is chloro, bromo, C1-6alkylcarbonyl or cyano; one of R3 and R4 is hydrogen or C1-4 alkyl and the other is C1-4 alkyl or R3 and R4 together are C2-5 polymethylene; and either R5 is hydroxy, C1-3 alkoxy or C1-8 acyloxy; and R2 is hydrogen and the cyclic amide moiety and R5 are trans; or R5 and R2 together form a bond, novel compounds within formula (I), processes for their preparation.
[EP0214743A2]
Patent IE-822733-L (IE)
Title: m-HYDROXYPHENYL SUBSTITUTED COMPOUNDS
IPC: C07D223/10
Filed: 1982-11-16
Abstract: m-Hydroxyphenyl substituted compounds of formula <IMAGE> (I) where R is an organic radical and R1 is hydroen or an organic radical are prepared by dehydrohalogenating a compound of formula <IMAGE> (II) (where X is chlorine or bromine, and R and R1 have the above meanings). Preferred novel starting materials of formula (II) are of the formula <IMAGE> (where R1 and X are as above, n is 2,3 or 4, R2 is hydrogen or lower alkyl and R3 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, cycloalkyl(lower)alkyl or aryl(lower)alkyl).
[US4463177A]
Patent IE-863249-L (IE)
Title: Composition for treating thrombosis
IPC: A61K38/46
Filed: 1986-12-12
Abstract: Combination product containing a fibrinolytic agent and an analogue of prostacycline for the treatment of thrombosis.
Patent NO-810525-L (NO)
Inventor: MICHEL ALFRED
IPC: F24H1/28
Filed: 1981-02-17
Abstract: A method for operating a heating plant having a boiler with a heat exchanger following the combustion chamber, such that it can be operated continuously and the exhaust gas temperature maintained at a predetermined value, in which a continuously controllable burner is employed and the effective heat exchanger area is adapted to the burner output.
Patent NO-811333-L (NO)
Inventor: TRUMMLITZ GUENTER
IPC: C07D275/06
Filed: 1981-04-15
Abstract: Compounds of the formula   <IMAGE>   wherein R1 is hydrogen or hydroxyl, and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases. The compounds as well as their salts are useful as sweetening agents.
Patent NO-820429-L (NO)
Inventor: KLAUS MICHAEL
IPC: C07C317/00
Filed: 1982-02-12
Abstract: This invention is directed to tetrahydronaphthalene and indane compounds and processes thereto. These compounds are useful as tumor inhibiting agents, in the treatment of neoplasms and dermatological conditions.
Patent NO-823128-L (NO)
Inventor: SIRCAR ILA
IPC: C07D403/12
Filed: 1982-09-15
Abstract: Substituted 4,5-dihydro-6-(substituted)-phenyl-3(2H)-pyridazinone compounds and 6-(substituted)phenyl-3(2H)-pyridazinone compounds and pharmaceutically acceptable salts thereof are useful as cardiotonic and antihypertensive agents. Said compounds cause a significant increase in myocardial contractility in the dog. Said compounds also cause a decrease in blood pressure in the spontaneously hypertensive rat. Said compounds are produced by reacting substituted  gamma -oxobenzene-butanoic acids with suitably substituted hydrazines to provide 4,5-dihydro-6-(substituted)phenyl-3(2H)-pyridazinones which are dehydrogenated to 6-(substituted)phenyl-3(2H)-pyridazinones. Both the 4,5-dihydro-6-(substituted)-phenyl-3(2H)-pyridazinones and the 6-(substituted)-phenyl-3(2H)-pyridazinones are useful as cardiotonic and antihypertensive agents. The compounds have the formula: <CHEM> where ....... represents a double or single bond and A is anyone of five types of heterocyclic ring-containing radicals, and R2, R3 and Y are hydrogen or various substituents.
Patent NO-844170-L (NO)
Inventor: GOEDHART MACHIEL
IPC: C11D3/12
Filed: 1984-10-18
Abstract: The use of a layered clay, e.g. a synthetic hectorite, is a rinse aid composition for use after a dishwashing operation significantly reduces the formation of spots and film on the rinsed articles when dry.
Patent NO-845111-L (NO)
Title: Informasjonsskilt, saerlig for veitrafikanter
Inventor: GAARDMAN ROGER STEN IVAR
IPC: G09F/
Filed: 1984-12-19
Abstract: Informasjonsskilt, særlig for veitrafikanter, innbefattende en plate (10) hvis frontside er forsynt med den nødvendige informasjon, samt i det minste én bærende stang (17) på hvilken platen (10) er fastgjort. Platen har en nedre horisontal kant som er omboyd for. å danne en flens (10a) som stikker ut på skiltets bakside vesentlig vinkelrett mot platens plan. Den plane platen (10) er på baksiden forsynt med en profilert plate (18) som hviler på den utstikkende flensen (10a) og tilnærmet dekker hele platens bakside. Derved for-
Patent NO-845151-L (NO)
Inventor: ZWART KLAAS
IPC: E21B31/107
Filed: 1984-12-20
Abstract: An upstroke wireline jar having a hammer 12 at the bottom end of an operating rod 3 which is axially slidable in a casing 2 having an anvil 13 at its upper end. This casing also includes a releasable coupling means which is biased downwards by a spring 5 to a rest position, said coupling means comprising a sleeve 4 which receives the rod 3 into its upper end and a plurality of arcuate segments 9 which are contained in apertures in the sleeve and engage in a circumferential groove 10 in the rod. Circumferential recesses 11 and 17 in the interior wall of the casing 2 are adapted to partially receive the segments when the sleeve is in appropriate registration therewith thereby facilitating disconnection and subsequent re-engagement of the operating rod with the sleeve. The spring 5 is mounted below the hammer so as to allow free travel of the latter along a substantial portion of the casing. The spring is provided with an upper abutment 6 mounted on a rod 7 the axial position of which is adjustable from outside the jar. At its bottom end the spring 5 abuts a flanged bush 15 which depends from the sleeve 4. A second spring 6 assists in biasing the sleeve to its rest position.