baber/WOPTO huggingface dataset:
Patent NZ-616755-A (NZ)
Title: Biomarkers for determining sensitivity of breast cancer cells to her2-targeted therapy
Inventor: KIM PHILLIP
IPC: G01N33/574
Filed: 2010-05-13
Abstract: Disclosed is an ex vivo method of determining the sensitivity of a cell to a compound that modulates HER2 activity, the method comprising: (a) contacting the cell with the compound; (b) lysing the cell to produce a cellular extract; (c) determining the activation level of HER2 and p95HER2 in the cellular extract produced from the cell; and (d) comparing the activation level of HER2 and p95HER2 determined in step (c) to a first reference activation level of HER2 and p95HER2 in a compound-sensitive cell treated with the compound and to a second reference activation level of HER2 and p95HER2 in a compound-resistant cell treated with the compound, wherein the presence of a similar or lower level of HER2 and p95HER2 activation in the cellular extract compared to the first reference activation level of HER2 and p95HER2 indicates that the cell is sensitive to the compound, and wherein the presence of a similar or higher level of HER2 and p95HER2 activation in the cellular extract compared to the second reference activation level of HER2 and p95HER2 indicates that the cell is resistant to the compound.
Patent NZ-618516-A (NZ)
Title: Foot orthotic design system
Inventor: EVERSON DAN FRANKLIN
IPC: A61F5/14
Filed: 2012-05-21
Abstract: A method for the selection of an orthotic for a patient's foot is disclosed. The patient's foot is subjected to one or more of (i) a supination resistance test (as defined); and (ii) Jack's test (as defined)and a test value(s) within a predetermined set of relative values for each test which is indicative of one or more properties of the patient's foot is ascribed. Each test value is recorded in a database and the test values are compared to control values indicative of one or more predetermined orthotic designs stored in the database; and an orthotic design(s) is selected from the predetermined orthotic designs dependent on that comparison
Patent NZ-629690-A (NZ)
Title: Space divider of a milking parlor arrangement, and milking parlor arrangement
Inventor: HENSEL DERK
IPC: A01K1/12
Filed: 2013-03-14
Abstract: A spacing partition including a pivoted robotic arm with a cluster of teat cups for milking cows is described. The partition seek to expedite the milking times by automatically attaching the teat cups to the udder, or at least positioning the cups below the udder for subsequent manual attachment. Dividers (4), when placed in series, form a battery of stalls for milking. Once cows are in the stalls, the arm (10) extends such that the cluster (5) is beneath the udder of the cow and is then attached to the teats of the cow either manually or automatically.
Patent NZ-702839-A (NZ)
Title: Vaccine and methods to reduce campylobacter infection
Inventor: HARGIS BILLY
IPC: A61K39/00
Filed: 2011-06-09
Abstract: Discloses a vector comprising a first polynucleotide sequence encoding an antigenic polypeptide of SEQ ID NO: 8 (cj0982) or a fragment thereof, the first polynucleotide sequence not natively associated with the vector. Said vector may further comprise the immunostimulatory polypeptide HMGB1.
Patent NZ-704889-A (NZ)
Title: Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid
Inventor: MANN RICHARD K
IPC: A01P13/00
Filed: 2013-07-19
Abstract: Provided herein are synergistic herbicidal compositions containing (a) a compound of formula (I): 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid, or an agriculturally acceptable salt or ester thereof and (b) triazolopyrimidine sulfonamides, including, but not limited to, cloransulam-methyl, diclosulam, florasulam, flumetsulam, metosulam, penoxsulam, and pyroxsulam. The compositions provide control of undesirable vegetation, e.g., in direct-seeded, water-seeded and transplanted rice, cereals, wheat, barley, oats, rye, sorghum, corn/maize, sugarcane, sunflower, oilseed rape, canola sugar beet, soybean, cotton, pineapple, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, aquatics, plantation crops, vegetables, industrial vegetation management (IVM) and rights of way (ROW).
Patent NZ-707073-A (NZ)
Title: Process for converting a biomass material
Inventor: DEL PAGGIO ALAN ANTHONY
IPC: C10G3/00
Filed: 2013-12-19
Abstract: A process for converting a biomass material comprising a) converting a biomass material in steps comprising: i) fermentation of a biomass material with one or more micro-organisms, to produce a fermentation broth comprising one or more carboxylic acids; ii) neutralization of the one or more carboxylic acids with the help of a buffering agent to produce one or more carboxylate salts; iii) transforming the one or more carboxylate salts into the one or more C3–C12 ketones, one or more C3–C12 alkanols or a combination thereof; b) contacting the one or more C3-C12 ketones, one or more C3–C12 alkanols or a combination thereof with hydrogen at a hydrogen partial pressure of more than 1.0 MegaPascal in the presence of a sulphided carbon-carbon coupling catalyst at a temperature in the range from equal to or more than 250°C to equal to or less than 450°C and at a WHSV in the range of from 0.2 to 2.5 kg feed per kg catalyst per hour; wherein the feed into step b) also contains in the range from equal to or more than 150 to equal to or less than 2000 ppmw sulphur and wherein the carbon-carbon coupling catalyst comprises equal to or more than 60wt% of a zeolite and in the range from equal to or more than 0.1%wt to equal to or less than 10wt% of a hydrogenation metal, based on the total weight of the carbon-carbon coupling catalyst.
Patent NZ-707905-A (NZ)
Title: Fastener advance delay for fastener driving tool
Inventor: LARGO MARC D
IPC: B25C1/08
Filed: 2011-11-14
Abstract: A nailer (10) which includes a power source (14) with a driving element in communication with the power source (14) for creating reciprocal movement of the driving element relative to a nose piece (32). The nailer has a magazine (32) connected to the nose piece (30) for feeding fasteners sequentially for being driven into a workpiece by the driving element. The nailer has a fastener delay mechanism (60) operatively associated with the magazine (32) and configured for engaging a subsequent fastener and delaying advancement of the subsequent fastener to the nosepiece until the driving element returns to a pre-firing position after driving a first fastener. The nailer includes a control program, and the delay mechanism is constructed and arranged to be controlled by the control program to energize the delay mechanism for a predetermined period of time. The delay mechanism is triggered by the position of the driving element. The nailer includes a piston position indicator switch. The delay mechanism includes an electromagnetic solenoid connected to the piston position indicator switch. The solenoid is activated once the piston moves from the pre-firing position. The solenoid is mounted for engaging a strip of fasteners between the first two fasteners of the strip. The delay mechanism including a reciprocating plunger mounted to extend transverse to a direction of movement of the fasteners in said magazine, being arranged for engaging a strip of fasteners between fasteners of the strip, and when energized, blocks movement of the fastener toward said nosepiece under control of said control program.
Patent NZ-710925-A (NZ)
Title: Chimeric antigen receptor and methods of use thereof
Inventor: WU CHIA-YUNG
IPC: C12N15/11
Filed: 2014-02-14
Abstract: The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided. The heterodimeric, conditionally active CAR comprises a) a first polypeptide comprising: i) a first member of a specific binding pair; ii) a first co-stimulatory domain; iii) a first member of a dimerization pair; and iv) a transmembrane domain interposed between the first member of a specific binding pair and the first co-stimulatory domain; and b) a second polypeptide comprising: i) a second member of the dimerization pair; and ii) an intracellular signaling domain; optionally further comprising a transmembrane domain and/or a second co-stimulatory domain, wherein the first and second members of the dimerization pair form a homodimer or a heterodimer in the presence of a dimerizing agent.
Patent NZ-713733-A (NZ)
Title: A mutant sialidase having trans-sialidase activity for use in production of sialylated glycans
Inventor: MIKKELSEN JØRN DALGAARD
IPC: C12N9/24
Filed: 2014-04-11
Abstract: The invention provides a mutant enzyme having trans-sialidase activity (EC 3.2.1.18), characterized by an enhanced trans-sialidase:sialidase ratio when compared to its parent sialidase enzyme. Further the enzyme may be used in a method for trans-sialylating mono- and oligo-saccharides, including galacto-oligosaccharides (GOS), fructo-oligosaccharides (FOS), malto-oligosaccharides (MOS), isomalto-oligosaccarides (IMO), lactulose, melibiose, maltose, glycosyl sucrose, lactosucrose and fucose. Trans-sialidated mono- and oligo- saccharides, produced with the mutant enzyme, are useful in preparing infant formula, a prebiotic nutritional supplement, and a food supplement.
Patent NZ-724907-A (NZ)
Title: Quinoxaline derivatives useful as fgfr kinase modulators
Inventor: VERMEULEN WIM
IPC: A61P35/00
Filed: 2015-03-26
Abstract: The invention relates to new quinoxaline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
Patent NZ-734197-A (NZ)
Title: Novel peptides and combination of peptides for use in immunotherapy against lung cancer, including nsclc and other cancers
Inventor: WEINSCHENK TONI
IPC: A61K35/17
Filed: 2016-04-22
Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to the tumorassociated T-cell peptide epitope KYLEKYYNL, that can serve as an active pharmaceutical ingredient of a vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
Patent NZ-739514-A (NZ)
Title: Rodent, worm and insect resistant irrigation pipe and method of manufacture
Inventor: RUSKIN RODNEY
IPC: F16L11/08
Filed: 2016-08-02
Abstract: An irrigation device has a single layer flexible tube having an inner portion and an outer portion. A plurality of outlets extend through the tube in a spaced relationship along a length of the tube. Finely-divided hydrophilic silica particles are dispersed in the outer portion of the tube and not the inner portion of the tube, the tube thereby having an increased surface hardness to deter rodent, worm or insect damage. The tube is a low-density polyethylene or a flexible polyvinylchloride (PVC).
Patent NZ-740801-A (NZ)
Title: Cutting tool
Inventor: JIA LE XIE
IPC: B23D21/08
Filed: 2018-03-16
Abstract: A cutting tool includes a housing having a blade opening and a biasing member having a securing portion, an engaging portion, and a semi-circular body portion in between the securing portion and the engaging portion. An annular blade is biased by the engaging portion towards the opening and against the housing, with the blade at least partially extending through the blade opening. The engaging portion extends away from the body portion and a plane defined by the body portion. By virtue of this arrangement the engaging portion is prevented from slipping in a manner that could jam the tool; and the tool is less likely to perform a nonuniform or spiral cut.
Patent NZ-764812-A (NZ)
Title: Child resistant slider, zipper closure system using slider, and methods of use
Inventor: ATHANS JOHN
IPC: B65D33/25
Filed: 2018-11-28
Abstract: A child resistant slider (16) includes a top member (54) and a pair of spaced legs (56, 58) depending from the top member, which provides adequate means for adults to open a reclosable zipper closure with male and female tracks having complementary profiles for interlocking and unlocking. At least a first leg of the spaced legs has a first tang (74) projecting laterally away from a remaining portion of the first leg and a remaining portion of the slider. The first tang has a separator plow (78). The tang can be movable to move the first plow into a position to be between the interlocked male and female tracks of a zipper closure to separate interlocking profiles of the zipper closure. In other examples, both legs include a projecting tang having a separator plow.
Patent PT-103712-A (PT)
Title: Estrutura em inox para acondicionamento de garrafas de gás embalado
Inventor: PIRES HUGO FILIPE RIBEIRO
IPC: B65D88/10
Filed: 2007-04-10
Abstract: O PRESENTE INVENTO REFERE-SE A UMA ESTRUTURA INOX PARA ACONDICIONAMENTO DE GARRAFAS DE GÁS EMBALADO, OU OUTRAS, EM TUBO NORMALIZADO, QUADRANGULAR, RECTANGULAR E TRAPEZOIDAL, O CONCEITO INOVADOR REPRESENTADO NO DESENHO, COM UM ÚNICO ACESSO PARA A MOVIMENTAÇÃO DE DESCARGA E CARGA DAS GARRAFAS, PELO LADO INTERIOR (6), COM UMA PORTA MÓVEL (2) NÃO REMOVÍVEL QUE SE MOVIMENTA VERTÍCALMENTE EM GUIAS INTEGRADAS E REPRESENTADO NA POSIÇÃO FECHADA (8), TENDO NO LADO OPOSTO A FRENTE FIXA (1), NO LADO INFERIOR O ESTRADO COMO BASE PARA ASSENTAMENTO ORDENADO DAS GARRAFAS (3), NOLADO SUPERIOR AS GUIAS DE ORIENTAÇÃO E ENCASTRAMENTO (4), NAS LATERAIS OS TOPOS FIXOS (5), UM CHIP/RFID (7), INCORPORADO PARA FORNECIMENTO DE DADOS Á GESTÃO INFORMATIZADA, COM A UTILIZAÇÃO DO INOX POR SER EXCELENTE CONDUTOR DA ELECTRICIDADE ESTÁTICA, CONSEGUE-SE ÍNDICES ELEVADOS DE SEGURANÇA, E A NÃO UTILIZAÇÃO DE TRATAMENTO DE SUPERFÍCIE NA SUA MANUTENÇÃO, PERMITE MAIOR LONGEVIDADE DIMINUINDO O PREJUÍZO AMBIENTAL.
Patent PT-104085-A (PT)
Title: Materiais cerâmicos de dimensão nanométrica, processo para a sua síntese e respectivas utilizações
Inventor: SILVA JOAO MANUEL CALADO DA
IPC: C01F7/162
Filed: 2008-05-27
Abstract: O PRESENTE INVENTO DIZ RESPEITO A MATERIAIS CERÂMICOS DE DIMENSÃO NANOMÉTRICA E QUE SE APRESENTAM SOB A FORMA DE MÚLTIPLAS ESTRUTURAS CRISTALINAS, COMPÓSITOS OU SOLUÇÕES SÓLIDAS, AO PROCESSO PARA A SUA SÍNTESE E RESPECTIVAS UTILIZAÇÕES. ESTES MATERIAIS SÃO ESSENCIALMENTE OBTIDOS POR DETONAÇÃO DE DUAS EMULSÕES DE ÁGUA EM ÓLEO (A/O), UMA DAS QUAIS É PREPARADA COM PERCURSORES DE FORMA A APRESENTAR UM REGIME DE DETONAÇÃO COM TEMPERATURA INFERIOR A 2000 ºC, E APRESENTAM UMA ELEVADA HOMOGENEIDADE QUÍMICA E DE FASES CRISTALINAS, INDIVIDUALMENTE EM CADA PARTÍCULA, BEM COMO UM CONJUNTO DE PROPRIEDADES COMPLEMENTARES PASSÍVEIS DE SEREM AJUSTADAS DE ACORDO COM AS APLICAÇÕES FINAIS, COMO DISTRIBUIÇÃO HOMOGÉNEA DAS PARTÍCULAS PRIMÁRIAS GRAU DE PUREZA QUÍMICO MUITO ELEVADO, TAMANHO DA CRISTALITE ABAIXO DOS 50 NM, ÁREAS DE SUPERFÍCIE POR UNIDADE DE MASSA ENTRE OS 25 E OS 500 M2/G E DENSIDADES REAIS DA PARTÍCULA SUPERIORES A 98% DA DENSIDADE TEÓRICA. ESTE CONJUNTO DE CARACTERÍSTICAS TORNA ESTES MATERIAIS, PARTICULARMENTE INDICADOS PARA UMA VASTA GAMA DE APLICAÇÕES NA ÁREA DA NANOTECNOLOGIA, COMO POR EXEMPLO NANOREVESTIMENTOS, NANOFLUIDOS MAGNÉTICOS, NANOCATALISADORES, NANO-SENSORES, NANOPIGMENTOS, NANOADITIVOS, NANOCOMPÓSITOS ULTRALEVES, NANOPARTÍCULAS PARA LIBERTAÇÃO DE DROGAS, NANOMARCADORES, FILMES NANOMÉTRICOS, ETC.
Patent PT-108625-A (PT)
Title: Elemento acoplador para placas de revestimento para pavimento e suas aplicações
Inventor: JOÃO MANUEL DE CARVALHO GOMES
IPC: F24D13/02
Filed: 2015-06-30
Abstract: A PRESENTE INVENÇÃO DIZ RESPEITO A PLACAS DE REVESTIMENTO CERÂMICO COM ELEMENTOS DE AQUECIMENTO IMPRESSOS E ENCAPSULADOS, INTERLIGADOS ENTRE PLACAS POR ELEMENTOS ACOPLADORES, EM PARTICULAR UMA ARGOLA E SISTEMAS DE AQUECIMENTO.UM ASPETO DA PRESENTE INVENÇÃO DIZ RESPEITO A UM ELEMENTO ACOPLADOR PARA PLACAS DE REVESTIMENTO PARA PAVIMENTO QUE COMPREENDEM UMA PLACA CERÂMICA, UM CIRCUITO ELÉTRICO E UM SUBSTRATO ISOLANTE COM UMA REENTRÂNCIA PARA RECEBER O REFERIDO ELEMENTO ACOPLADOR, EM QUE O REFERIDO ELEMENTO COMPREENDE: UM SEGMENTO CONDUTOR; UM REVESTIMENTO DO SEGMENTO CONDUTOR EM MATERIAL POLIMÉRICO ELETRICAMENTE ISOLANTE; DUAS PROTRUSÕES RESILIENTES E CONDUTORAS LIGADAS AO SEGMENTO CONDUTOR PARA INTERCONECTAR DUAS PLACAS DE REVESTIMENTO.
Patent RU-94002316-A (RU)
Inventor: KLAS ENSMA
IPC: F25D3/10
Filed: 1994-01-27
Abstract: FIELD: cooling means for medical treatment. SUBSTANCE: in methods and apparatuses for surface cooling liquid coolant being under pressure is distributed through profile member made of open cellular foamplast. Method is especially useful for local freezing of warts or other new formation before their removal from skin of patient or animal. EFFECT: increased effectiveness.
Patent RU-94030195-A (RU)
Inventor: BUGAETS E S
IPC: H01L21/78
Filed: 1994-08-11
Abstract: FIELD: electronic devices. SUBSTANCE: device has thin dielectric plate to which semiconductor crystal and terminals are connected. Said semiconductor crystal has contact points, is covered by sealing dielectric cover and is connected to dielectric plate by its front side. Crystal also has recesses which provide access to contact points which serve as terminals. EFFECT: increased functional capabilities.
Patent RU-94037830-A (RU)
Inventor: LABZIN V A
IPC: A01G23/00
Filed: 1994-10-10
Abstract: FIELD: agriculture. SUBSTANCE: apparatus has power cylinder 1 with piston 3, inlet opening 2 communicated with pressure pipeline, outlet opening 4 communicated with atmosphere and cutting tool 5. Method involves advancement of pulling device to cause motion of power cylinder 1 relative to piston 3 toward inlet opening 2, with cutting tool 5 being immovable. Movement of power cylinder 1 causes outlet opening 4 to close and, as a result, pressure in left cavity to be increased till balance between compressed air press force and cutting tool draft is obtained. When pressure is excessive, piston and cutting tool connected with it are abruptly displaced to undercut seedlings roots. EFFECT: increased efficiency by improved seedling adaptability on planting place and minimized damage to roots in the process of undercutting. 1 dwg
Patent RU-94044774-A (RU)
Title: Energy absorber
Inventor: MATJUSHCHENKO A V
IPC: F16F7/12
Filed: 1994-12-20
Abstract: FIELD: mechanical engineering; impact energy absorber devices. SUBSTANCE: energy absorber has housing where bush and deforming rod are coaxially arranged. Deforming rod has radial bead and bush has square thread on its inner surface whose flute receives spiral insert of similar profile at axial clearance; insert is mounted on rod and its end rests against bead of rod. Innovation of invention: availability of spiral deformable insert; diameter of rod bead is equal to inner diameter of bush thread; spiral insert is mounted on rod at initial radial pressure. Spiral insert may be of constant or varying section lengthwise. Besides that, longitudinal groove may be provided over entire extended length of spiral insert. EFFECT: operation of energy absorber in two directions; constant and varying absorbing force; energy absorber may be reused after replacement of spiral insert. 3 cl, 3 dwg
Patent RU-94046368-A (RU)
Inventor: D SOUZA HENRY M
IPC: A61B3/107
Filed: 1994-11-29
Abstract: FIELD: medical equipment. SUBSTANCE: multifunctional testing system for determining cornea surface shape has camera with display, controlled computer (charge-coupled device), "frame trap" plate and image digital treatment algorithm with corresponding processing circuits. Charge coupled device camera receives reflection of target, for example, placid disk, from surface of cornea. Image of charge coupled device reflection of placid disk from surface of cornea is trapped by plate of "frame trap" and subjected to digital analysis after it has been processed in edge detector. The latter reduces number of points of data, which has to be processed for determining radius of each ring at image of reflected placid disk. Received data are processed for getting contour of surface and for creating representation of data of circuit formed in such a manner in table, graphic or pictorial form. The system may be used for designing custom contact lenses. Complete topographic map of cornea can be build characterized by almost instant indication of radius of curvature of cornea from enough large number of points for precise evaluation of shape of surface. EFFECT: improved efficiency of operation.
Patent RU-95105413-A (RU)
Inventor: KAMERON DIN OSMAN
IPC: C05F17/02
Filed: 1993-09-13
Abstract: FIELD: reworking of wastes. SUBSTANCE: device 10 has recycling chamber 11 where compost layer 12 may be formed, inlet 21 of recycling chamber 11 for addition of organic wastes to compost layer 12, ventilating devices 28 to facilitate aerobic digestion of compost layer 12 in recycling chamber 11, draining devices 43 to avoid conversion of wastes contained in recycling chamber into anaerobic state and access devices 39, 40 and 41 to give access and to remove compost formed in recycling chamber. Recycling chamber has plastic accumulating tank, access device 39,40 and 41 which include closed conveyer 40 for transportation of compost from lower zone of compost layer 12. Recycling chamber 11 may be provided with air-permeable separating device 38 for separation of box 15 from compost layer 12. Partial filling of accumulating tank with active layer of compost is preferable. EFFECT: enhanced efficiency. 13 cl, 3 dwg
Patent RU-95106579-A (RU)
Inventor: FEDCHISHIN V G
IPC: B63B1/10
Filed: 1995-04-25
Abstract: FIELD: building of sea-going ships; designing of storm-resistant ships with weatherworks. SUBSTANCE: three floats are located on each side of hull. Each float is articulated with carriage of strut by means of swivel cantilever held in intermediate position by means of two powerful springs; two vertical gear racks are articulated with cantilever to transmit torque to electric generator shaft through overrunning clutches, pair of bevel gears, step-up gear and inertial clutch. Semi-submersible fore and aft vertical struts are interconnected by means of horizontal hollow strips having hydrodynamic shape. EFFECT: avoidance of effect of wave energy on hull at partial conversion of this energy into electrical or mechanical energy. 3 cl, 2 dwg
Patent RU-95108330-A (RU)
Inventor: ROBERT KOFFMEN
IPC: A61P35/00
Filed: 1993-08-18
Abstract: FIELD: pharmacy, bioactive substances. SUBSTANCE: pharmaceutical composition has at least one pharmaceutically acceptable carrier and active substance. Active substance is taken from the group involving interleukin-4, interleukin-10, combination of interleukin-4 and interleukin-10 and antibodies against interleukin-4 and interleukin-10 taken at effective amount. EFFECT: enhanced effectiveness of composition.