baber/WOPTO huggingface dataset:
Patent WO-2021061815-A1 (WO)
Title: COMPOSITIONS AND METHODS FOR MODULATING HEPATOCYTE NUCLEAR FACTOR 4-ALPHA (HNF4α) GENE EXPRESSION
Inventor: RAO TIMSI
IPC: C12N15/63
Filed: 2020-09-23
Abstract: The present invention provides agents and compositions for modulating expression ( e.g ., enhanced or reduced expression) of a hepatocyte nuclear factor 4 alpha (HNF4α) gene by targeting an HNF4α expression control region and methods of use thereof for treating an HNF4α associated disorder,  e.g ., cirrhosis.
Patent WO-2021067462-A1 (WO)
Inventor: JOSEPH VINAY
IPC: H04W48/10
Filed: 2020-09-30
Abstract: Apparatus, methods and computer-readable media for broadcast of multiple physical cell identity ranges are disclosed herein. A user equipment (UE) can receive system information (SI) containing physical cell identities (PCIs) associated with a first cell type or a second cell type, in which the first cell type is accessible to a first set of UEs and the second cell type is accessible to a second set of UEs and a second set of PCIs containing PCIs corresponding to a set of cells of the second cell type. The UE can also monitor for cells with a PCI in the first set of PCIs or the second set of PCIs. A base station may generate the SI indicating the first set of PCIs and the second set of PCIs. Additionally, the base station can communicate the SI to one or more UEs.
Patent WO-2021071784-A1 (WO)
Title: Physical medical element sizing systems and methods
Inventor: SHIRAZIAN POURYA
IPC: G06T19/20
Filed: 2020-10-05
Abstract: An exemplary system is configured to instruct a display device to render a virtual medical element representative of a physical medical element over a target region within an image of an internal space of a patient, the target region depicting an anatomical surface to be covered by the physical medical element; receive, while the virtual medical element is rendered over the target region, user input that sets at least one of a pose of the virtual medical element within the image or a size of the virtual medical element; and determine, based on the user input and on depth data representative of a depth map for the internal space, physical dimensions for the physical medical element.
Patent WO-2021076726-A1 (WO)
Inventor: LEONG CHIAKEN
IPC: H01L23/31
Filed: 2020-10-15
Abstract: A process for conformally coating passive surface mount components soldered to a printed circuit substrate of a lidless flip-chip ball grid array package includes affixing a stiffener ring to the substrate before forming a conformal coating on the passive surface mount components. The stiffener ring is affixed to the substrate so that the plurality of passive surface mount components and the integrated circuit die are contained within an opening formed by the stiffener ring. After affixing the stiffener ring to the substrate, the conformal coating is formed on the passive surface mount components. The conformal coating extends over each of the passive surface mount components, around a periphery of each of the passive surface mount components, and under each of the passive surface mount components. A product made according to the process is also disclosed.
Patent WO-2021096645-A1 (WO)
Title: Authorizations associated with externally shared communication resources
Inventor: MONTAZERI MICHAEL
IPC: H04L47/80
Filed: 2020-10-20
Abstract: Various embodiments of the present disclosure are directed to a group-based communication apparatus that is configured to enable end-users (e.g., non-admin users) to initiate, by way of client devices, generation of a shareable resource associated with a group-based communication resource identifier to efficiently authorize communication between client devices associated with different organization identifiers in group-based communication interfaces associated with a shared group-based communication resource identifier.
Patent WO-2021126816-A1 (WO)
Title: Dosing regimen of a kras g12c inhibitor
Inventor: HENARY HABY
IPC: A61P35/00
Filed: 2020-12-15
Abstract: A method of treating cancer comprising administering to a subject in need thereof the compound AMG510 in a daily dose of 180 mg, 270 mg, 360 mg, 540 mg, 720 mg, or 960 mg.
Patent WO-2021046571-A1 (WO)
Title: Deriving csi using a subset of configured csi-rs resources
Inventor: MANOLAKOS ALEXANDROS
IPC: H04L25/02
Filed: 2020-08-25
Abstract: A user equipment (UE) may receive a configuration that indicates a set of channel state information reference signals (CSI-RSs) to be measured by the UE for deriving channel state information (CSI), one or more time domain resources for which the UE is to derive the CSI, and a time domain resource for transmission of a CSI report that includes the CSI, wherein the one or more time domain resources for which the UE is to derive the CSI occur after the time domain resource for transmission of the CSI report; determine that the UE cannot measure a first subset of CSI-RSs included in the set of CSI-RSs; derive one or more parameters for the CSI report based at least in part on measuring a second subset of CSI-RSs included in the set of CSI-RSs; and transmit the CSI report in the time domain resource for transmission of the CSI report.
Patent WO-2021102467-A1 (WO)
Inventor: MITCHELL JAMES
IPC: A61B5/0205
Filed: 2020-11-18
Abstract: Vascular access assemblies are disclosed herein. In one example, a vascular access assembly comprises a proximal catheter, a distal catheter, and a junction positioned between the proximal and distal catheters and configured to position the proximal and distal catheters in fluid communication. The junction may comprise one or more sensors configured to obtain physiological and/or operational measurements. The junction may be configured to wirelessly transmit the measurements to one or more local or remote computing devices for monitoring by a caregiver.
Patent WO-2021134094-A1 (WO)
Inventor: WANG JUN
IPC: B65D75/00
Filed: 2020-12-11
Abstract: Described herein is a recyclable packaging having an exposed outermost surface, the recyclable packaging comprising: a wall comprising an inner surface opposite an outer surface, the wall having a multi-layer structure that includes a first layer comprising biaxially oriented polypropylene, a second layer comprising metallized cast polypropylene, a third layer comprising cast polypropylene; and a cavity at least partially surrounded by the wall.
Patent WO-2021168399-A1 (WO)
Title: Novel methods for creating alpha-n-methylated polypeptides
Inventor: FREEMAN MICHAEL F
IPC: C07K14/375
Filed: 2021-02-22
Abstract: Provided herein are methods and compositions for producing alpha-N-methylated peptides  in vitro  and  in vivo . This disclosure also provides  in vivo  and  in vitro  methods for producing highly diverse alpha-N-methylated peptide libraries by methylating natural or non-natural alpha-N-methyltransferase target peptides.
Patent WO-2021183591-A1 (WO)
Title: Fast in-memory technique to build a reverse csr graph index in an rdbms
Inventor: LOZI JEAN-PIERRE
IPC: G06F16/901
Filed: 2021-03-10
Abstract: In an embodiment, a computer obtains a mapping of a relational schema of a database to a graph data model. The relational schema identifies vertex table(s) that correspond to vertex type(s) in the graph data model and edge table(s) that correspond to edge type(s) in the graph data model. Each edge type is associated with a source vertex type and a target vertex type. Based on that mapping, a forward compressed sparse row (CSR) representation is populated for forward traversal of edges of a same edge type. Each edge originates at a source vertex and terminates at a target vertex. Based on the forward CSR representation, a reverse CSR representation of the edge type is populated for reverse traversal of the edges of the edge type. Acceleration occurs in two ways. Values calculated for the forward CSR are reused for the reverse CSR. Elastic and inelastic scaling may occur.
Patent WO-2021183731-A1 (WO)
Title: System and method for printing on a clear polymeric film web
Inventor: CYMAN THEODORE F
IPC: B41J2/21
Filed: 2021-03-11
Abstract: A system (20) and method for printing on clear polymeric film web (24) are disclosed. A first stationary inkjet print unit (44, 60, 70, 82) has first ejection nozzles that span a width of the clear polymeric film web and a second stationary inkjet print unit (44, 60, 70, 82) has second ejection nozzles that span the width of the clear polymeric film web. A web transport conveys the clear polymeric film web past the stationary inkjet print units. First and second print controllers operate the first and second stationary inkjet print units to deposit drops of a first and a second material on the clear polymeric film web at a first and a second resolution, respectively. In addition, dimensions and position of a page element to be printed on the clear polymeric film web are adjusted to compensate for distortion that may occur to the printed page element due to shrinking of the clear polymeric film web.
Patent WO-2021202600-A1 (WO)
Title: Small molecule inhibitors of influenza hemagglutinin
Inventor: WOLAN DENNIS W
IPC: C07D413/10
Filed: 2021-03-30
Abstract: Disclosed are small molecule inhibitors of influenza HA, and methods of using them to treat or prevent HA-mediated diseases and conditions.
Patent WO-2021202846-A1 (WO)
Title: On demand positioning reference signals and per band deployment aspects
Inventor: AKKARAKARAN SONY
IPC: G01S5/00
Filed: 2021-04-01
Abstract: Disclosed are techniques for wireless communication. In an aspect, a user equipment (UE) transmits a request for a first set of base stations to transmit on demand positioning reference signals (PRS) in a first band, measures the on demand PRS from the first set of base stations in the first band, measures periodic PRS from a second set of base stations operating in a second band, and sends, to a positioning entity, positioning measurements of at least the on demand PRS and the periodic PRS.
Patent WO-2021202883-A1 (WO)
Title: Methods for production of oligosaccharides
Inventor: LIU JINGJING
IPC: C12N15/63
Filed: 2021-04-01
Abstract: Disclosed herein are genetically modified microorganisms and related methods for the enhanced production and export of oligosaccharides. The microorganisms described herein express major facility superfamily proteins such as CDT-1, which allows for the export of oligosaccharides. Variants of CDT-1 exhibit higher activity regarding oligosaccharide export. The microorganisms described herein express formation enzymes for the production of oligosaccharides. Means to export oligosaccharides into the growth medium are provided herein.
Patent WO-2021202991-A1 (WO)
Title: Sensor-based systems and methods for diagnostic and field use detection of nucleic acids
Inventor: WEAVER DAVID
IPC: C12Q1/6806
Filed: 2021-04-02
Abstract: Devices and methods for the detection of nucleic acids (e.g., RNA, DNA) are described. The nucleic acid can be obtained or derived from a pathogen, such as a virus. In one embodiment, the virus is a coronavirus (e.g., SARS-CoV-2) related to the disease COVID-19. Accordingly, devices and methods may be used in the field as point-of-care devices to test a subject (e.g., a patient) for the presence of the SARS-CoV-2 virus or another nucleic acid.
Patent WO-2021211766-A1 (WO)
Title: Cross-link interference (cli) enhancements
Inventor: ZHANG QIAN
IPC: H04W74/00
Filed: 2021-04-14
Abstract: A method of wireless communication is presented. The method includes receiving, at a user equipment (UE) from a base station, a measurement configuration comprising quasi-co-location (QCL) information for a serving reception beam. The method also includes measuring cross-link interference experienced on the serving reception beam. The method further includes transmitting the QCL information for the serving reception beam and a corresponding sounding reference signal-reference signal received power (SRS-RSRP) or cross-link information-received signal strength indicator (CLI-RSSI) to the base station.
Patent WO-2021231278-A1 (WO)
Inventor: UMANA PABLO
IPC: A61K39/00
Filed: 2021-05-10
Abstract: La présente demande concerne des méthodes pour stimuler une réponse immunitaire chez un individu, comprenant l'administration d'une composition de cellules nucléées (par exemple, des PBMC) comprenant un antigène exogène intracellulaire en conjonction avec l'administration d'un immunoconjugué comprenant un polypeptide variant d'IL-2 et un second polypeptide. Le polypeptide variant d'IL-2 présente une affinité réduite vis-à-vis de la sous-unité α du récepteur IL-2. Le second polypeptide cible une cellule tumorale ou un lymphocyte T.
Patent WO-2021247571-A1 (WO)
Title: Vaginal microbiota compositions
Inventor: WALSH DANA M
IPC: A61K35/747
Filed: 2021-06-01
Abstract: Compositions and methods for treating patients are disclosed. An example composition may include a vaginal microbiota composition. The vaginal microbiota composition may include a mixture of bacteria. The mixture of bacteria may include  Lactobacillus crispatus ,  Lactobacillus gasseri ,  Lactobacillus jensenii , and  Lactobacillus rhamnosus .
Patent WO-2021258062-A1 (WO)
Inventor: BABAEE SAHAB
IPC: A61F2/07
Filed: 2021-06-21
Abstract: L'invention concerne une plate-forme de stent permettant une administration intravasculaire locale de substances thérapeutiques par une injection multipoint d'agents médicamenteux dans les parois vasculaires et les surfaces endocardiaques. Plus particulièrement, un stent endovasculaire injectable constitué d'une enveloppe du type kirigami qui est enroulée autour d'un actionneur linéaire souple et utilisée pour l'administration intravasculaire locale de substances thérapeutiques. Cette plate-forme répond à un besoin non satisfait de traitement d'une sténose aortique et d'une maladie cardiovasculaire artérioscléreuse.
Patent WO-2022006053-A1 (WO)
Title: Multi-radius magnetron for physical vapor deposition (pvd) and methods of use thereof
Inventor: SONG JIAO
IPC: C23C14/14
Filed: 2021-06-29
Abstract: Methods and apparatus for processing a substrate are provided herein. In embodiments, a magnetron assembly for use in a PVD chamber includes: a base plate having a first side, a second side opposite the first side, and a central axis; a magnet plate rotatably coupled to the base plate, wherein the magnet plate rotates with respect to the base plate about an offset axis; a magnet assembly coupled to the magnet plate offset from the offset axis and configured to rotate about the central axis and the offset axis; a first motor coupled to the base plate to rotate the magnet assembly about the central axis; and a second motor coupled to the magnet plate to control an angular position thereof and to position the magnet assembly in each of a plurality of fixed angular positions defining a plurality of different fixed radii.
Patent WO-2022010773-A1 (WO)
Title: Structural load cell cases for encasing sensors in robotic systems
Inventor: REILLY MICHAEL
IPC: G01G21/23
Filed: 2021-07-02
Abstract: A structural load cell case for a pick and place robotic system that prevents torsion, bending, and overloading from damaging sensors is disclosed. The structural load cell case includes a base, an inner tube that houses the load cell, and a roller sleeve. The base includes a compression spring interfaced with a first part of the load cell. The roller sleeve includes a plurality of roller bearings in contact with the inner tube. The inner tube is free to slide along an axis of the roller sleeve up to pre- determined limits, but is constrained from rotating or translating in directions other than the axis of the roller sleeve.
Patent WO-2022040114-A1 (WO)
Inventor: HURTUBISE VENESIA L
IPC: C11D7/50
Filed: 2021-08-17
Abstract: An azeotropic cleaning solvent composition has from about 96 to about 98 weight percent 1,1,1,3,3,3-hexafluoro-2-methoxypropane ("HFMOP") and from about 2 to about 4 weight percent acetone, for example, about 97 weight percent HFMOP and about 3 weight percent acetone. Another composition of the invention has a weight ratio of HFMOP to acetone of about 24 to about 99, for example, about 24 to 49. Conventional additives such as surfactants, lubricants and co-solvents may be present in an amount not to exceed about 10 weight percent of the composition. A method of the invention comprises contacting an article of manufacture with the solvent composition in order to clean the article of manufacture and then removing the solvent composition from the article of manufacture.
Patent WO-2022081253-A1 (WO)
Inventor: CHANDRASEKARAN SATHISH ARUMUGAM
IPC: H04L29/12
Filed: 2021-08-19
Abstract: La présente invention concerne un système et un procédé pour un dispositif client destiné à être utilisé avec un premier dispositif de réseau Wi-Fi, un second dispositif de réseau Wi-Fi et un serveur externe. Le premier dispositif de réseau Wi-Fi est configuré avec une première configuration de sous-réseau et le serveur externe a une liste de configurations de sous-réseau réservé stockée dans celui-ci. Le dispositif client comprend une mémoire et un processeur configuré pour exécuter des instructions stockées sur ladite mémoire afin d'amener ledit dispositif client à : accéder à la liste de configurations de sous-réseau réservé à partir du serveur externe ; choisir une configuration de sous-réseau sur la base de la liste de configurations de sous-réseau réservé ; et donner l'instruction au second dispositif de réseau Wi-Fi d'établir un second réseau ayant la configuration de sous-réseau choisie.
Patent WO-2023033798-A1 (WO)
Title: Method of modifying a space-filling lattice using a boundary-representation model
Inventor: BUTLER SIMON
IPC: G06F30/10
Filed: 2021-08-31
Abstract: A computer-implemented method of determining the dimensions of a space-filling lattice in a solid model is disclosed. Initially information including a lattice, a set of faces and data indicating a spatial relationship between the lattice and each face in the set is received. A set of points indicating the intersection positions where each rod intersects a face is then identified, and each intersecting rod is classified based upon whether or not each subset of mutually tolerantly coincident points within the set indicates that a rod is divided by a face. If a rod is divided the lattice is modified by adding a new ball where the rod is divided and classifying the new rods either side of it. These classifications are then spread to adjacent rods without crossing any new ball to establish the complete set of surviving rods. Each connected set of surviving rods is used to instantiate a new lattice.
Patent WO-2022081927-A1 (WO)
Inventor: NASVESCHUK CHRISTOPHER
IPC: C07D403/04
Filed: 2021-10-14
Abstract: L'invention concerne des composés tricycliques qui dégradent des néo-substrats destinés à être utilisés dans le traitement de troubles décrits dans la description, comprenant, par exemple, une prolifération cellulaire anormale, des maladies neurodégénératives et des maladies auto-immunes.
Patent WO-2022086849-A1 (WO)
Inventor: CHANG HENRY
IPC: H04W40/12
Filed: 2021-10-18
Abstract: A remote user equipment (UE) device receives a sidelink (SL) discovery message from each of a plurality of candidate relay UE devices where each SL discovery message is transmitted using a discovery resource of a discovery resource pool of a plurality of discovery resource pools. Each discovery resource pool is allocated to a range of Reference Signals Received Power (RSRP) levels. Each relay UE device measures an RSRP level of a link to a destination and transmits the SL discovery message using a discovery resource from the discovery pool associated with the RSRP range containing the measured RSRP level. The remote UE device selects (or reselects) a relay UE device from the candidates based, at least partially, on the RSRP ranges of the links from the candidate relay devices to the destination.
Patent WO-2022093787-A1 (WO)
Title: Wideband vector modulator phase shifter
Inventor: NING KANG
IPC: H04B7/00
Filed: 2021-10-26
Abstract: Methods and apparatus for implementing passive wideband phase shifters are described. The phase shifters exhibit good linearity over a wide range of frequencies. Furthermore at least some features are directed to allowing the phase shifters to be implemented in some embodiments in a relatively compact manner making such embodiments well suited for supporting arrays and/or other implementations where a large number of phase shifters are to be implemented in a relatively small chip area.
Patent WO-2022203724-A1 (WO)
Title: Integrating robotic process automations into operating and software systems
Inventor: NOTT BRANDON
IPC: G06F9/54
Filed: 2021-10-27
Abstract: Disclosed herein is a computing system that includes a memory and a processor coupled to the memory. The memory storing processor executable instructions for an interface engine that integrates robotic processes into a graphic user interface of the computing system. The processor executes the interface engine to cause the computing system to receive inputs via a menu of the graphic user interface and to automatically determine the robotic processes for display in response to the inputs. The interface engine further generates a list including selectable links corresponding to the robotic processes and displays the list in association with the menu.
Patent WO-2022094235-A1 (WO)
Title: A lighted visual trip indicator module for circuit breakers
Inventor: EDWARDS BENJAMIN W
IPC: H01H83/20
Filed: 2021-10-29
Abstract: A visual trip indicator for a circuit breaker is disclosed. The electronic components of a visual trip indicator are enclosed in a module that attaches to the circuit breaker handle or within pocket defined in the circuit breaker housing. The visual trip indicator includes a light source operated by a state machine which clearly indicates which circuit breaker, of a group of circuit breakers or in a poorly illuminated enclosure, is tripped. The visual trip indicator also indicating, by a coded light signal, the approximate remaining life of an independent power supply powering the visual trip indicator.
Patent WO-2022094343-A1 (WO)
Title: Anti-sars-cov-2 antigen antibodies and related compositions and methods
Inventor: YUSKO ERIK
IPC: C07K16/10
Filed: 2021-10-29
Abstract: Provided are antibodies that specifically bind a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antigen. Nucleic acids that encode one or both of the variable chain polypeptides of an antibody of the present disclosure are also provided, as are cells that include such nucleic acids. Also provided are compositions that include the antibodies of the present disclosure, including in some instances, pharmaceutical compositions. Methods of making and using the antibodies of the present disclosure are also provided. In certain aspects, provided are methods that include administering to an individual in need thereof, e.g., an individual having or suspected of having a SARS-CoV-2 infection, a therapeutically effective amount of an antibody of the present disclosure.
Patent WO-2022094451-A1 (WO)
Inventor: XU SHUAI
IPC: A61B5/113
Filed: 2021-11-02
Abstract: La présente invention concerne un dispositif électronique pour mesurer des paramètres physiologiques d'un sujet vivant, comprenant au moins une première unité de mesure inertielle (UMI) et une seconde UMI, la première UMI et la seconde UMI étant synchronisées dans le temps et séparées spatialement et mécaniquement l'une de l'autre ; et une unité de micro-dispositif de commande (MCU) couplée électroniquement à la première UMI et à la seconde UMI pour le traitement de flux de données provenant de la première UMI et de la seconde UMI.
Patent WO-2022094474-A1 (WO)
Title: Compositions for and methods of co-analyzing chromatin structure and function along with transcription output
Inventor: DIAO YARUI
IPC: C12Q1/68
Filed: 2021-11-02
Abstract: Disclosed herein are compositions for and methods of performing a multi-omics assay comprising analyzing chromatin structure and function and analyzing the transcriptome using the same population of cells. Disclosed herein are compositions for and methods of performing a high-throughput chromosome conformation capture on accessible DNA and mRNA-Seq co-assay (HiCAR).