baber/WOPTO huggingface dataset:
Patent MX-2021014043-A (MX)
Title: Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of disorders related thereto.
Inventor: BLACKBURN ANTHONY C
IPC: C07D491/107
Filed: 2018-12-05
Abstract: The present invention relates to compounds of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the beta-3 adrenergic receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of a beta-3 adrenergic receptor-mediated disorder, such as, heart failure; cardiac performance in heart failure; mortality, reinfarction, and/or hospitalization in connection with heart failure; acute heart failure; acute decompensated heart failure; congestive heart failure; severe congestive heart failure; organ damage associated with heart failure (e.g., kidney damage or failure, heart valve problems, heart rhythm problems, and/or liver damage); heart failure due to left ventricular dysfunction; heart failure with normal ejection fraction; cardiovascular mortality following myocardial infarction; cardiovascular mortality in patients with left ventricular failure or left ventricular dysfunction; left ventricular failure; left ventricular dysfunction; class II heart failure using the New York Heart Association (NYHA) classification system; class III heart failure using the New York Heart Association (NYHA) classification system; class IV heart failure using the New York Heart Association (NYHA) classification system; LVEF < 40% by radionuclide ventriculography; LVEF â¿¤35% by echocardiography or ventricular contrast angiography; and conditions related thereto.
Patent MX-2021014686-A (MX)
Title: Methods and uses for treating cancer.
Inventor: MEDINA MANUEL HIDALGO
IPC: A61K31/4545
Filed: 2020-05-28
Abstract: The present disclosure includes a method for treating or ameliorating a cancer or the effects of a cancer in a subject in need thereof comprising administering to the subject an effective amount of a hedgehog inhibitor (HHI) or a pharmaceutically acceptable salt thereof, and a chemotherapeutic agent (CTA).
Patent MX-2022000397-A (MX)
Title: Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases.
Inventor: FREDERICK BRIAN TROY
IPC: A61P1/00
Filed: 2020-07-09
Abstract: The present invention provides novel peptide inhibitors of the interleukin-23 receptor, and related compositions and methods of using these peptide inhibitors to treat or prevent a variety of diseases and disorders, including inflammatory bowel diseases.
Patent MX-2022002339-A (MX)
Title: Alpha-d-galactopyranoside derivatives.
Inventor: BOLLI MARTIN
IPC: A61K31/422
Filed: 2020-08-28
Abstract: The present invention relates to compounds of Formula (I) wherein Ar1, R1 and R2 are as described in the description, and A is 4,5-dihydroisoxazole-3,5-diyl, imidazolidin-4-one-l,3-diyl, oxazol-2- one-3,5-diyl and oxazolidine-2-one-3,5-diyl, l,2,3-triazole-l,4-diyl, isoxazole-3,5-diyl, imidazole-1, 4-diyl, and isothiazole-3,5-diyl; and their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of Formula (I), and especially to their use as Galectin-3 inhibitors.
Patent MX-2022002608-A (MX)
Title: A method and system for the secure transmission of funds.
Inventor: SMITH ANDREW
IPC: G06Q40/02
Filed: 2019-09-02
Abstract: Method and system for transacting a secure money transfer which is operative to transfer funds, in a first currency, from a first sending bank account, at a first location, to a second recipient bank account at a second location. An aim of the invention is to provide a system that operates across borders and in real-time. Another aim of the invention is to provide a system that guarantees the existence of funds and ensures funds are transferred, thereby reducing the risk of banks of being exposed to Herstatt risk.
Patent MX-2022003700-A (MX)
Title: Drug delivery device.
Inventor: EILERTSEN LARS
IPC: A61M5/28
Filed: 2020-09-29
Abstract: A drug delivery device may include a housing having an opening and a drug storage container including a delivery member having an insertion end configured to extend at least partially through the opening during a delivery state. The device may also include a guard moveably positioned adjacent to the opening and a plunger having a generally cylindrical body portion extending along a longitudinal axis of the container and at least one flange extending radially outwardly from the body portion, wherein the plunger is moveable toward the distal end of the container to expel a drug through the delivery member. The device may further include a plunger biasing member configured to urge the plunger toward the distal end of the container and a releaser member defining a guide configured to receive the at least one flange and an indicator configured to generate an audible signal indicating an end of drug delivery.
Patent MX-2022006217-A (MX)
Title: High hyaluronate multi-purpose disinfection solutions for ophthalmic applications.
Inventor: GERATHS CHRISTIAN
IPC: A61L12/14
Filed: 2020-12-04
Abstract: The present invention relates to ophthalmic formulations wherein a synergistic combination of three different classes of disinfectants (a multimeric biguanide compound, a quaternary ammonium compound and an antifungal/anti-acanthamoeba compound, in particular a combination of polyhexamethylene biguanide, Polyquaternium-1 and myristamidopropyl dimethylamine) enables the use of high concentrations of hyaluronate for providing better comfort and support of corneal health without compromising antimicrobial efficacy. The novel ophthalmic formulations support the use of more than 7.5 times higher concentrations of hyaluronate than are present in currently marketed multi-purpose disinfection solutions.
Patent MX-2022010640-A (MX)
Title: Apparatus and method for extracting oil from plant material.
Inventor: WIRTZ ROBERT N
IPC: B01D17/04
Filed: 2021-02-26
Abstract: A process and apparatus for extracting plant oil from plant material by cooling an alcohol solvent to a temperature of -40Â°C or lower, contacting the plant material with the cold solvent to extract plant oil to provide a solvent and plant oil mixture, heating the mixture to convert the solvent to a gaseous state to thereby separate the solvent from the plant oil, and cooling the separated gaseous solvent to a liquid to recover the solvent. The apparatus may include a heat exchanger to cool the alcohol solvent, a centrifuge configured to receive and contact a batch of plant material with the cold solvent to extract oil from the plant material to provide a solvent and oil mixture, and a programmable logic controller to monitor and control the temperature of the cold solvent, control the centrifuge to agitate the solvent in contact with the plant material for a period of time and to rotate for a period of time to separate the mixture from the plant material. A process and apparatus may also decarboxylate the separated plant oil.
Patent MX-2022012337-A (MX)
Title: Methods of treating systemic sclerosis.
Inventor: PELOSO PAUL
IPC: A61P17/00
Filed: 2021-04-02
Abstract: Provided is a method of treating systemic sclerosis in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of 2-(4-methoxy-3-(3-methylphenethoxy)benzamido)-2,3-dihydro-1H-in dene-2-carboxylic acid (Compound 1), or a pharmaceutically acceptable salt thereof, for a dosing period of at least about 24 consecutive weeks.
Patent MX-2022013353-A (MX)
Title: Medical device audible and visual alarm synchronization.
Inventor: WOJTYSIAK SLAWOMIR EDWARD
IPC: G16H20/17
Filed: 2021-04-22
Abstract: A system includes a server including a clock and a plurality of medical devices in network communication with the server. Each medical device includes at least one alarm mechanism and an internal clock. A first medical device of the plurality of medical devices is configured to receive a clock synchronization data from the server, update the internal clock of the first medical device based on the clock synchronization data, provide an alarm signal of a first type at a first time, and provide a subsequent alarm signal of the first type at a second time. The second time occurs at a predetermined interval from the first time. Additionally, the second time is the same time the alarm signal of the first type is provided by a second medical device of the plurality of medical device.
Patent MX-2022014408-A (MX)
Title: Connector for mainline pipe and outlet pipe.
Inventor: KEENE KURT MICHAEL
IPC: E03F3/04
Filed: 2021-05-26
Abstract: The embodiments of the present disclosure provide a system for connecting a mainline pipe with an outlet pipe. The system comprises an outlet pipe configured to be coupled to a mainline pipe near a proximal end of the outlet pipe, a first sleeve disposed on an exterior surface of the outlet pipe and comprising a first lip at a proximal end of the first sleeve, and a second sleeve disposed on the first sleeve and comprising a second lip at a proximal end of the second sleeve. The first lip of the first sleeve may be configured to abut an interior surface of the mainline pipe, and the second lip of the second sleeve may be configured to abut an exterior surface of the mainline pipe.
Patent MX-NL04000051-A (MX)
Title: Process for the production of an immunosuppressant.
Inventor: SREENILAYAM GOPEEKRISHNAN
IPC: A61P43/00
Filed: 2002-08-29
Abstract: The present invention discloses process of producing sodium salt of immuno-suppressant of formula I: (I).
Patent MX-NL06000075-A (MX)
Title: Method for obtaining mucilage from salvia hispanica l.
Inventor: MASCARUA JOAQUIN ACEVEDO
IPC: A23L29/238
Filed: 2006-10-12
Abstract: Process for extracting mucilage from Salvia hispanica, a plant of the genus and species of Salvia hispanica Linnaeus, Lamiaceae or Labiate, which is commercially known as: White chia seeds, mixture of different colour chia seeds, black chia seeds golden chia seeds, Anutra and Salba, the process being characterised in that it includes the following main steps: Bringing chia seeds into contact with water so as to obtain a product best known as: Mucilage. The mucilage thus obtained is subjected to extraction processes using sonication and/or stirring methods, the extract being separated by a high pressure process so as to obtain an improved yield, the drying and pulverization stages are also included. The invention further includes some uses of aqueous and dry mucilage previously obtained by the aforementioned process in the food, cosmetic and pharmaceutical industry.
Patent MX-PA00012750-A (MX)
Title: Method for hair repair, styling and straightening.
Inventor: YAMASHITA YUKO
IPC: A61Q5/02
Filed: 2000-01-11
Abstract: A method for hair repair, styling and straightening which comprises shampooing and rinsing the hair, applying a liquid alkaline straight-perming agent onto the hair, allowing the perming agent to remain on the hair until the hair becomes structurally elastic, then rinsing off the perming agent as the hair continuously being in the structurally elastic state, further applying a liquid hair repairing agent onto the hair, compressing the hair under heating, subjecting the hair structure to an oxidative pre-setting, applying an acidic rinse onto the hair, and treating the hair with a neutralizer over a period sufficient for relieving the structurally elastic state of the hair.
Patent MX-PA00012936-A (MX)
Title: Polyketides and their synthesis.
Inventor: MCARTHUR HAMISH ALASTAIR IRVIN
IPC: C07K19/00
Filed: 1999-06-29
Abstract: A polyketide synthase ("PKS") of Type I is a complex multienzyme including a loading domain linked to a multiplicity of extension domains. Ths first extension module receives an acyl starter unit from the loading domain and each extension module adds a further ketide unit which may undergo processing (e.g. reduction). We have found that the Ksq domain possessed by some PKS's has decarboxylating activity, e.g. generating (substituted) acyl from (substituted) malonyl. The CLF domain of type II PKS's has similar activity. By inserting loading modules including such domains into PKS's not normally possessing them it is possible to control the starter units used.
Patent MX-PA01001101-A (MX)
Title: Synthetic fireplace log and method of producing.
Inventor: TUTUPALLI LOHIT
IPC: C10L5/44
Filed: 1999-07-26
Abstract: A low cost and an environmentally-friendly synthetic firelog is made by mixing specially processed waxed-cardboard or other waxed coated papers of varying proportions with a binder/fuel. The finder/fuel consists of a petroleum wax or a mixture of waxes, the nature and extent of which is suitably modified by in situ admixture with the paraffin wax already present in the waxed-cardboard. Sawdust or other wood fillers may also be added. Upon thorough incorporation of the materials, the resulting mixture is extruded, molded, compressed, or otherwise formed, such that the resulting mass is sufficiently solid to hold its shape at normal room temperature.
Patent MX-PA01009743-A (MX)
Title: Ir and/or sm promoted multi-metal oxide catalyst.
Inventor: SANJAY CHATURVEDI
IPC: C01G15/00
Filed: 2001-09-27
Abstract: A catalyst comprising a promoted mixed metal oxide is useful for the vapor phase oxidation of an alkane or a mixture of an alkane and an alkene to an unsaturated carboxylic acid and for the vapor phase ammoxidation of an alkane or a mixture of an alkane and an alkene to an unsaturated nitrile. The multi-metal catalyst contains Ir and/or Sm.
Patent MX-PA01012387-A (MX)
Title: Keratinocyte growth factor-2 formulations.
Inventor: UNSWORTH EDWARD
IPC: A61P17/02
Filed: 2000-06-02
Abstract: The invention is directed to liquid and lyophilized forms of Keratinocyte Growth Factor-2 (KGF-2) and derivatives thereof. This invention further relates to the formulations of KGF-2 for therapeutic use, for example, to promote or accelerate wound healing.
Patent MX-PA01012744-A (MX)
Title: Film and use thereof for coating objects.
Inventor: RINK HEINZ-PETER
IPC: C08J5/18
Filed: 2000-06-21
Abstract: Film for use in a paint finish has specific glass transition, environmental and use temperatures and specific tan delta values. Film has a Tg1 of maximum loss factor tan delta between -20 and 70 deg C, a tan delta at environmental temperature (Te) of above 0.1, a further Tg of maximum tan delta above the use temperature (Tu), where Te is at most Tu, preferably less than Tu, and tan delta at Te after heating and/or actinic irradiation is below 0.1, where tan delta is measured at a film thickness of 40+/-10 mu . Independent claims are included for the preparation of a paint finish by applying the above film at Tu and heating and/or actinically irradiating and also for automobile bodies, furniture, building parts, containers, packaging and articles for daily use with at least one coating obtained from the above film..
Patent MX-PA01013235-A (MX)
Title: Indole derivatives, process for their preparation, pharmaceutical compositions containing them and their medicinal application.
Inventor: ADAMS DAVID REGINALD
IPC: C07D495/04
Filed: 2000-08-04
Abstract: A chemical compound of formula (I) wherein: R1 and R2 are independently selected from hydrogen and alkyl; R3 is alkyl; R4, R6 and R7 are independently selected from hydrogen, halogen, hydroxy, alkyl, aryl, amino, alkylamino, dialkylamino, alkoxy, aryloxy, alkylthio, alkylsulfoxyl, alkylsulfonyl, nitro, carbonitrile, carbo-alkoxy, carbo-aryloxy and carboxyl; R5 is selected from hydrogen, halogen, hydroxy, alkyl, aryl, amino, alkylamino, dialkylamino, alkoxy, aryloxy, alkylthio, alkylsulfoxyl, alkylsulfonyl, nitro, carbonitrile, carbo-alkoxy, carbo-aryloxy and carboxyl; A is a 5- or 6-membered partially unsaturated or aromatic heterocyclic ring or a 5- or 6-membered partially unsaturated carbocyclic ring, wherein if A is a 6-membered partially unsaturated carbocyclic ring then at least one of R4 to R7 is other than hydrogen, and pharmaceutically acceptable salts, addition compounds and prodrugs thereof, and the use thereof in therapy, particularly as an agonist or antagonist of a 5HT receptor, particularly a 5HT2C receptor, for instance in the treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders; diabetes insipidus, and sleep apnea, and particularly for the treatment of obesity.
Patent MX-PA02001876-A (MX)
Title: Triazinylaminostilbene derivative as fluorescent whitening agents.
Inventor: ROHRINGER PETER
IPC: D06L3/12
Filed: 2000-09-04
Abstract: The present invention relates to compounds having formula (1): wherein each R1 represents, independently, a linear C1C4alkylene residue which is unsubstituted or substituted by hydroxy, C1C4alkyl, C1C4alkoxy, C1C4hydroxy or alkoxyalkoxy, OCOM, OCOC1C4alkyl, or an amino acid residue from which a hydrogen atom on the amino group has been removed; each R2 represents, independently, a linear C1C4alkylene residue which is unsubstituted or substituted by hydroxy, C1C4alkyl, C1C4alkoxy, C1C4hydroxy or alkoxyalkoxy, OCOM, OCOC1C4alkyl, CO2M, CO2C1C4alkyl SO3M or phenoxy which is unsubstituted or substituted by halogen, C1C4alkyl or C1C4alkoxy, CO2M or CO2C1C4alkyl, NH2 or mono or disubstituted amino; or phenyl which is unsubstituted or substituted by 1 to 3 SO3M, SO2NHC1C4alkyl, SO2NH2, CO2M, CO2C1C4alkyl, CONH2, CONHC1C4alkyl, NHCOC1C4alkyl or mono or disubstituted amino groups; each R3 represents independently, hydrogen, C1C4alkyl, halogen, cyano, SO3M, SO2NH2, SO2NHC1C4alkyl, CO2M, CO2C1C4alkyl, CONH2, CONHC1C4alkyl, or NHCOC1C4alkyl; M is hydrogen, an alkali metal atom, ammonium or a cation formed from an amine and m is an integer of 1 to 3, a process for their preparation and use of the compounds as optical brightening agents for synthetic or natural organic materials or for removing stain in photographic materials.
Patent MX-PA02004127-A (MX)
Title: Method and system for the copying of documents.
Inventor: KIA SILVERBROOK
IPC: A63F13/30
Filed: 2000-10-20
Abstract: The invention concerns a system and method enabling the copying of documents. It has specific application to the archiving and retrieval, and the scanning and reproduction, of documents which are or which may be capable of interacting with a computer system or network. Such a document has coded data printed on it allowing it to interact with the computer system or network by use of a sensing device operated by a user. Specifically, the method involves scanning a document which may contain both document information and coded data indicative of an identity of the document, forming a digital image of the document, and detecting, if the document contains said coded data indicative of the identity of the document, the coded data. If the document does contain such coded data, stored data representing the content of the document is accessed, and, depending on the operating instructions, either a copy of the document is printed, together with coded data indicative of an identity of the copy being printed on the copy, or data representing a copy of the document is stored, the stored data including a unique identifier for said copy. The invention can be employed for the printing of documents, the archiving and retrieval of documents, and the scanning and reproduction of documents. In copying documents, it can be used to produce pages of far higher quality than those produced by conventional photocopying means, often irrespective of the physical quality of the page to be copied.
Patent MX-PA02005014-A (MX)
Title: Nucleic acid construct for optimized production of products.
Inventor: TRECO DOUGLAS A
IPC: C12N15/16
Filed: 2000-11-17
Abstract: The present invention features a nucleic acid construct for expressing a product, e.g., a small peptide such as GLP 1. The construct includes a nucleic acid sequence encoding a signal peptide and a nucleic acid sequence which encodes the pro region of somatostatin or a functional fragment thereof. The construct can further include a sequence encoding the small peptide or the construct can be used to express an endogenous genomic sequence encoding the small peptide. The present invention further features genetically engineered cells, and methods of using such constructs or cells.
Patent MX-PA02007241-A (MX)
Title: Packaging material made of a biaxially oriented polyolefin film.
Inventor: DRIES THOMAS
IPC: B32B27/32
Filed: 2001-01-23
Abstract: The invention relates to a packaging material made of a multilayer oriented polyolefin film, which comprises a base layer and at least one first outer layer, whereby the first outer layer is placed in contact with itself or in contact with the opposing surface of the film or in contact with the surface of another film. This first outer layer contains an additive which absorbs light within the wavelength range of a laser such that when the film is locally irradiated by the laser, the area of irradiation experiences an increase in temperature that causes the polyolefin of the first outer layer to soften or melt in the irradiated area and to bond to another layer when cooled.
Patent MX-PA02007721-A (MX)
Title: Pane provided with a coating which prevents deposits and or damage, and a process and device for its production.
Inventor: WETERINGS ANTONIUS ALOYSIUS MA
IPC: A01G9/14
Filed: 2001-02-12
Abstract: Greenhouse provided with glass panes, at least the inner side of the said panes being provided with a coating which prevents deposits on and or damage to the said pane. To prevent condensation which forms against the pane from forming drops, it is proposed for the coating to be of hydrophilic design. A process which allows this to be achieved is based on ordinary glass which is provided with a coating which prevents deposits on and or damage to the said pane and involves subjecting this coating to an etching treatment. Panes can be entered in the treatment assembly where several stations are provided to apply both the coating preventing deposits and or damage and to realise the etching treatment.
Patent MX-PA02008018-A (MX)
Title: Zero heel polyester process.
Inventor: MOATS SAMUEL MARTIN
IPC: C08G63/78
Filed: 2001-02-16
Abstract: A process for the preparation of polyesters of a glycol and a dicarboxylic acid which comprises the following steps: a) introducing a feedstock comprising one or more glycols and one or more dicarboxylic acids or monoalcohol esters thereof into a reactor vessel, b) heating the feedstock to an elevated temperature to cause the glycols and the acids or monoalcohol esters thereof to polycondense into a polyester, c) removing all of the polyester from the reactor vessel; wherein step b) is carried out in the absence of a preformed polyester (zero heel process). A catalyst is added in step a) or b) or both.
Patent MX-PA02009258-A (MX)
Title: 4,5 dihydro 1h pyrazole derivatives having cb1.
Inventor: VAN VLIET BERNARDUS J
IPC: A61P/
Filed: 2001-03-22
Abstract: The present invention relates to a group of novel 4,5 dihydro 1H pyrazole derivatives which are potent antagonists of the cannabis CB1 receptor. The compounds have general formula (I) wherein R and R1 are the same or different and represent phenyl, thienyl or pyridyl which groups may be substituted with 1, 2 or 3 substituents Y or R and or R1 represent naphtyl, R2 represents hydrogen, hydroxy, C1 3 alkoxy, acetyloxy or propionyloxy, Aa represents one of the groups (i), (ii), (iii), (iv) or (v), Bb represents sulfonyl or carbonyl, R3 represents benzyl, phenyl, thienyl or pyridyl which may be substituted with 1, 2 or 3 substituents Y or R3 represents C1 8 branched or unbranched alkyl or C3 8 cycloalkyl, or R3 represents naphtyl.