baber/WOPTO huggingface dataset:
Patent RU-2695905-C2 (RU)
Title: Mechanical block for the implementation of loading technology in the form of the blade or well in the drilling and explosive works (variants)
Inventor: Luksha Sergej Viktorovich
IPC: F42D1/08
Filed: 2017-11-17
Granted: 2019-07-29
Abstract: FIELD: mining. 
     SUBSTANCE: invention relates to the field of mining and is used in blasting operations. Mechanical failure for the implementation of the technology of charging the production in the form of a hole or a well in drilling and blasting operations is made in the form of a gate valve of the wedge type, which constructively includes two components: an outer sleeve with sliding longitudinal cheeks and a wedge element located in its cavity contacting their reciprocal surfaces. End face of the smaller area of the wedge element is provided with a rod member disposed along the axis of the spacer and passing through the opening in the abutment end face of the main outer sleeve with an outlet beyond it. In the embodiments of mechanical failure, additional locking elements having an opening for passage of the rod member are provided. According to the 1st variant: the wedge element is equipped with two additional wedge surfaces that are displaced in the circumferential direction relative to its main wedge surfaces, and in the cavity of the main outer sleeve there is an additional sleeve structurally identical to the main bushing that contacts the inner surfaces of the cheeks with additional wedge surfaces of the wedge element. According to the second variant: in the cavity of the outer sleeve, between its sliding longitudinal cheeks, there is an additional elastic locking device for the locking, made, for example, from rubber, which contacts the reciprocal surfaces of the wedge element and the outer sleeve. According to the third variant: in the cavity of the outer sleeve between its sliding longitudinal cheeks there is an additional locking device for locking, made in the form of an ampoule, which contacts the reciprocal surfaces of the wedge element and the outer sleeve, which is filled with a solidifying structure. Rod element of the wedge element, in all variants, passes through additional elements of the outer sleeve, while being kinematically connected to the main outer sleeve by means of a ratchet engagement of the umbrella type, the locking members of which are arranged along the length of the rod member and on the inner surface of the hole formed in the end surface of the outer sleeve with the possibility of their preliminary relative fixation before installation in the cavity of the development. 
     EFFECT: invention makes it possible to improve the reliability of locking the die. 
     3 cl, 11 dwg
Patent RU-2732952-C2 (RU)
Title: Inhibitor of certain protein kinases
Inventor: ZHAO XINGDONG
IPC: A61P35/00
Filed: 2016-04-28
Granted: 2020-09-24
Abstract: FIELD: chemistry. 
     SUBSTANCE: invention relates to a new compound of formula (I) or a pharmaceutically acceptable salt thereof. In formula (I)  
     
       
     
     Q is 6-member heteroaryl containing one or two heteroatoms selected from N; W is selected from N and CН; Z is selected from N and CR 6 ; R 1  is selected from heterocyclyl-C 1-4  alkyl, where heterocyclyl is 6–12-member mono- or bicyclic ring containing one or two nitrogen atoms or one or two nitrogen atoms and one oxygen atom, and alkyl and heterocyclyl are unsubstituted or substituted with at least one substitute, such as one, two, three or four substitutes independently selected from R X ; each R 2  is hydrogen; each R 3  is independently selected from hydrogen and C 1-6  alkyl, where alkyl is unsubstituted or substituted with one, two, three or four substitutes independently selected from R X ; or two R 3  together with carbon atoms, to which they are bonded, form 3–7-member cyclic ring not containing additional heteroatoms and optionally substituted with 1, 2 or 3 groups R X ; R 4  is selected from hydrogen and halogen; each R 5  is hydrogen; each R 6  is independently selected from hydrogen and fluorine; each R X  is independently selected from C 1-6  alkyl, 6-member heterocyclyl containing two nitrogen atoms, halogen, -NR a1 R b1  and -OR a1 , where alkyl and heterocyclyl are unsubstituted or substituted with at least one substitute, such as one, two, three or four substitutes independently selected from R Y ; each R a1  and each R b1  are independently selected from hydrogen and C 1-6  alkyl; R Y  is independently selected from C 1-10  alkyl; m is 2 or 3; n is selected from 0, 1 and 2; p is selected from 0, 1, 2 and 3; q is selected from 1, 2 and 3. 
     EFFECT: compounds have cyclin-dependent kinase 4/6 (CDK4/6) inhibitor properties and can be used for treating CDK4/6 related diseases, for example, for treating proliferative diseases. 
     23 cl, 6 tbl, 169 ex
Patent RU-2718179-C2 (RU)
Inventor: LADYAGIN YURIJ OLEGOVICH
IPC: F41B15/00
Filed: 2017-12-04
Granted: 2020-03-31
Abstract: FIELD: weapons and ammunition.SUBSTANCE: electric shock mine of directed action includes housing, power supply source, high-voltage source of damaging current, infrared, ultrasonic, microwave, mechanical or combined motion sensor, unitary cartridges of remote electric shock weapon, electromechanical or solid-state high-voltage commutator of damaging current voltage. Activation is performed automatically or by operator signal.EFFECT: creation of electric shock mine.9 cl, 4 dwg
Patent RU-2697797-C2 (RU)
Title: Genetic construct for inducing proliferation of peripheral monocytes in vitro
Inventor: CHUMAKOV STEPAN PETROVICH
IPC: C12N5/16
Filed: 2017-12-28
Granted: 2019-08-19
Abstract: FIELD: biotechnology.SUBSTANCE: disclosed is a genetic construct for inducing the proliferation of peripheral monocytes and dendrite cells in vitro derived from human blood, comprising sequences coding transcription factors c-Mus and BMI1, as well as their binding self-splitting peptide sequence of Thosea asigna T2A virus, providing polycistronic expression of transcription factors under the control of one EF1alpha promoter. Said construct is derived from expression plasmid lentiviral vector pLEF1a-tagRFP, including a number of regulatory sequences: 5' and 3' LTR long end repeats, Rev dependent element (RRE or Rev-response element), Env is a regulatory sequence providing packaging of a viral genome into a viral particle structure with formation of a virion, cPRT - central polypurine path, a post-transcriptional regulatory element WPRE, an EF1alpha promoter.EFFECT: invention provides effective constitutive expression of transcription factors s-Mus and BMI1 when introducing said construct into peripheral monocytes and dendritic cells.1 cl, 3 dwg, 3 ex
Patent RU-2742171-C2 (RU)
Title: Suppression of tumors using human placenta derived intermediate natural killer cells and immunomodulating compounds
Inventor: CHZHAN Syaokuj
IPC: A61K35/51
Filed: 2010-03-26
Granted: 2021-02-02
Abstract: FIELD: medicine. 
     SUBSTANCE: invention refers to a method of treating an individual. Method of treating an individual suffering from a malignant tumor, comprising administering to said individual recovered natural killer cells containing recovered CD56+, CD16−, CD3− natural killer cells derived from placenta, where said placental intermediate natural killer cells are recovered from placental perfusate and express one or more micro-RNAs hsa-miR-100, hsa-miR-127, hsa-miR-211, hsa-miR-302c, hsa-miR-326, hsa-miR-337, hsa-miR-497, hsa-miR-512-3p, hsa-miR-515-5p, hsa-miR-517b, hsa-miR-517c, hsa-miR-517c. 518a, HSA-mir-518e, HSA-mir-519d, HSA-mir-520g, HSA-mir-520h, hsa-miR-564, hsa-miR-566, hsa-miR-618 or hsa-mir-99A at a detectably higher level than natural killer cells of peripheral blood. 
     EFFECT: above described method is effective in treating tumorous diseases. 
     1 cl, 12 dwg, 20 tbl, 8 ex
Patent RU-2709560-C2 (RU)
Title: High-strength manganese steel containing aluminium, method of producing sheet steel product from said steel and sheet steel product obtained according to said method
Inventor: PALTSER Peter
IPC: C21D8/02
Filed: 2016-08-03
Granted: 2019-12-18
Abstract: FIELD: metallurgy. 
     SUBSTANCE: invention relates to metallurgy, namely to high-strength aluminum-containing manganese steel used in automotive industry, shipbuilding, aerospace industry, and so forth. Steel has the following chemical composition, wt. %: C: 0.01 to 0.3, Mn: 4 to 10, Al: 1 to 4, Si: 0.01 to 1, Cr: 0.1 to 4, Mo: 0.02 to 1, P: less than 0.1, S: less than 0.1, N: less than 0.3, optionally, at least one of: V: from 0.01 to 1, Nb: from 0.01 to 1, Ti: from 0.01 to 1, Sn: from 0 to 0.5, Cu: from 0.005 to 3, W: from 0.03 to 3, Co: from 0.05 to 3, Zr: from 0.03 to 0.5, Ca: from 0.0005 to 0.1, iron and unavoidable impurities - the rest. Steel has tensile strength Rm from 800 MPa to 1700 MPa, elongation at breaking A50 from 6 % to 45 %, preferably from 8 % to 45 %, and microstructure containing from 5 to 65 % residual austenite. 
     EFFECT: steel has high deformation properties, high resistance to delayed formation of cracks and hydrogen embrittlement. 
     14 cl
Patent RU-2737432-C2 (RU)
Inventor: ZHANG YAO
IPC: C08F220/18
Filed: 2017-06-27
Granted: 2020-11-30
Abstract: FIELD: lubricants. 
     SUBSTANCE: invention relates to a polymer mixture suitable for use in a depressant additive for lubricating oils, to production and use thereof. Polymeric mixture acceptable for use in depressant additive for lubricating oils consists of n components of polymer or contains them, wherein each of said n polymer components independently represents additive polymers from monomer of formula (I) and/or mixture thereof, or n polymer components, each independently consist of substantially one or more structural units represented by formula (I-1), or contain them. Symbol n is an integer in the closed interval [5, 50]. In formula (I) or formula (I-1) definition of each group and numerical value is given in description. When average number of carbon atoms in side chain of polymer i-component, as determined according to nuclear magnetic resonance method, is expressed as X i , where symbol i is an arbitrary integer from 1 to n, there is ratio X 1 <X 2 <...<X n−1 <X n . Also disclosed are versions of the method of producing the disclosed polymer mixture, a depressant based thereon, a lubricating oil composition using the disclosed mixture and a polymerisation control method. 
        (I) 
        (I-1). 
     EFFECT: technical result is disclosed polymer mixture demonstrates excellent effect of lowering of pour point for lubricating oils and wide adaptability for lubricant base oils, when used as a depressant additive. 
     28 cl, 1 dwg, 13 tbl, 7 ex
Patent RU-2746705-C2 (RU)
Inventor: VEJ Endryu
IPC: A61P35/00
Filed: 2017-07-21
Granted: 2021-04-19
Abstract: FIELD: pharmaceutics. 
     SUBSTANCE: invention relates to the field of medicine and pharmaceutics, namely to a combination for  treatment of malignant growths, comprising: (a) BCL-2 inhibitor selected from: (i)  N -(4-hydroxyphenyl)-3-{6-[((3 S )-3-(4-morpholinylmethyl)-3,4-dihydro-2(1 H )-isoquinolinyl)carbonyl]-1,3-benzodioxol-5-yl}- N -phenyl-5,6,7,8-tetrahydro-1-indolizine carboxamide, (ii) 5-(5-chloro-2-{[(3 S )-3-(morpholine-4-ylmethyl)-3,4-dihydroisoquinoline-2(1 H )-yl]carbonyl}phenyl )- N -(5-cyano-1,2-dimethyl-1 H -pyrrol-3-yl)- N -(4-hydroxyphenyl)-1,2-dimethyl-1 H -pyrrole-3-carboxamide or salts thereof, and (iii) 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine-1-yl)- N -[(3-nitro-4-{[(oxan-4-yl)methyl]amino}phenyl)sulfonyl]-2-[(1 H -pyrrolo[2,3- b ]pyridine-5-yl)oxy]benzamide (ABT-199); and (b) an MCL1 inhibitor selected from: (iv) ( 2R )-2-{[( 5Sa )-5-{3-chloro-2-methyl-4-[2-(4-methylpiperazine-1-yl)ethoxy]phenyl}-6-(5-fluorofuran-2-yl)thieno[2,3 -d ]pyrimidin-4-yl]oxy}-3-(2-{[1-(2,2,2-trifluoroethyl)-1 H -pyrazol-5-yl]methoxy}phenyl)propionic acid, and (v) ( 2R )-2-{[( 5Sa )-5-{3-chloro-2-methyl-4-[2-(4-methylpiperazine-1-yl)ethoxy]phenyl}-6-(4-fluorophenyl)thieno[2,3 -d ]pyrimidine-4-yl]oxy}-3-(2-{[2-(2-methoxyphenyl)pyrimidine-4-yl]methoxy}phenyl)propionic acid or salts thereof; and to a medicinal product containing said combination and to use thereof for treatment of malignant growths. 
     EFFECT: group of inventions provides a synergetic effect of the combination. 
     41 cl, 17 dwg, 24 tbl, 13 ex
Patent RU-2742365-C2 (RU)
Title: Heat exchanger
Inventor: TOUBIANA EPHRAIM
IPC: F28D9/00
Filed: 2017-11-09
Granted: 2021-02-05
Abstract: FIELD: power engineering. 
     SUBSTANCE: heat exchanger (1) is proposed for heat exchange between first fluid medium passing in longitudinal direction (X) and second fluid medium, wherein said heat exchanger (1) comprises: two parallel plates (6) spaced apart so as to form passage (7) for circulating said first fluid, at least one first and one second rows (8a, 8b) of ribs (9) located perpendicularly between said plates (6), wherein said first and second rows (8a, 8b) extend in a longitudinal direction, wherein ribs (9) of said first row (8a) are preferably arranged in staggered order relative to ribs (9) of said second row (8b), wherein each rib (9) is limited in longitudinal direction by first edge (10) and second edge (11), wherein said first edge (10) has on each of its ends a zone of connection with corresponding plate (6). Said zones of connection of said first edge (10) are inclined respectively at angle (A) and at angle (B) relative to normal (N) to plates (6) in plane (P), perpendicular to said plates (6) and parallel to direction (X), wherein said first edge (10) and said second edge (11) of each of ribs (9) have an identical profile in said plane (P). 
     EFFECT: invention allows observing required dimensional and geometric tolerances after fabrication. 
     10 cl, 10 dwg
Patent RU-2762342-C2 (RU)
Title: Ready-made composition for evaporation of electronic vaping device and electronic vaping device with such a composition
Inventor: FARISS MARC W
IPC: A24F40/00
Filed: 2017-10-17
Granted: 2021-12-20
Abstract: FIELD: tobacco industry. 
     SUBSTANCE: group of inventions relates to a ready-made composition for evaporation of an electronic vaping device and to an electronic vaping device with the specified ready-made composition for evaporation. The ready-made composition for evaporation contains: one or more polyol compounds; one or more chelating agents containing one or more of ethylenediaminetetraacetic acid, diethylenetriamine pentacetic acid and nitrilotriacetic acid; nicotine and substance for vapor formation, provided with the possibility of vapor formation from the ready-made composition for evaporation. One or more polyol compounds are one or more of mannitol, erythritol, xylitol and sorbitol. The concentration of one or more polyol compounds is equal to or greater than 0.2 percent and equal to or less than 8 percent by weight. The concentration of one or more chelating agents is equal to or greater than 0.001 percent and equal to or less than 0.05 percent by weight. Substance for vapor formation is at least one of propylene glycol, glycerol or glycerin.  
     EFFECT: increase in the stability of the ready-made composition for evaporation in the presence of oxygen and redox transition metals. 
     12 cl, 4 dwg
Patent RU-2759308-C2 (RU)
Inventor: FON ARB DZHEFFRI MAJKL
IPC: F16K49/00
Filed: 2017-12-06
Granted: 2021-11-11
Abstract: Изобретение относится к запирающим элементам клапанов, а конкретнее к цельным запирающим элементам клапана, имеющим встроенные проточные каналы, сформированные с помощью аддитивного производства. Запирающий элемент клапана содержит: цельный запирающий элемент клапана, имеющий впускное отверстие, выпускное отверстие, параллельное указанному впускному отверстию, встроенный проточный канал, гидравлически связанный с впускным отверстием и выпускным отверстием, и канал, выполненный с возможностью размещения вала клапана для позиционирования цельного запирающего элемента клапана, причем указанный проточный канал проходит в поперечном направлении от впускного отверстия к выпускному отверстию и выполнен с возможностью размещения потока текучей среды через впускное отверстие, циркуляции этого потока внутри запирающего элемента клапана и выпуска потока текучей среды через выпускное отверстие. 3 н. и 12 з.п. ф-лы, 13 ил.
Patent RU-2762128-C2 (RU)
Title: Frequency-selective limiter
Inventor: MORTON METTYU A
IPC: H01P1/22
Filed: 2018-05-24
Granted: 2021-12-15
Abstract: FIELD: electrical engineering.SUBSTANCE: invention relates to attenuator devices, in particular to frequency-selective limiters. A frequency-selective limiter, containing: magnetic material with the first and the second opposite surfaces and a set of conductors placed on the first surface of magnetic material to form a coplanar waveguide transmission line, differs in that the first of the specified set of conductors, corresponding to the first signal conductor, has a width that is decreased from the first end of the coplanar waveguide transmission line to the second, another end of the coplanar waveguide transmission line.EFFECT: reduction in the threshold power value, at which the provision of the required non-linearity occurs without changing the structure of magnetic material located near the transmission line.22 cl, 3 dwg
Patent RU-2769122-C2 (RU)
Title: Система и способ для сборки шин
Inventor: SLOTS ANTONIE
IPC: B29D30/20
Filed: 2018-06-13
Granted: 2022-03-28
Abstract: Изобретение относится к системе для сборки шин. Система содержит первый барабан, второй барабан и первые станции. Система для сборки шин дополнительно содержит первую опору, первое несущее устройство, которое перемещает первый барабан относительно первой опоры, вторую опору и второе несущее устройство, которое перемещает второй барабан относительно второй опоры. Первое несущее устройство выполнено с возможностью перемещения вдоль первой опоры в первой плоскости позиционирования. Второе несущее устройство выполнено с возможностью перемещения вдоль второй опоры в первой плоскости позиционирования. Первая опора выполнена с возможностью обеспечения опоры для первого несущего устройства снизу по отношению к первой плоскости позиционирования. Вторая опора выполнена с возможностью обеспечения подвешивания второго несущего устройства сверху по отношению к первой плоскости позиционирования. Кроме того, изобретение относится к способу позиционирования первого барабана и второго барабана относительно первых станций посредством использования вышеупомянутой системы. Технический результат – повышение скорости сборки шин. 2 н. и 26 з.п. ф-лы, 3 ил.
Patent RU-2760315-C2 (RU)
Title: Косметическое средство и способ его получения
Inventor: BORTS MIKHAIL SAMUILOVICH
IPC: A61K8/73
Filed: 2020-04-21
Granted: 2021-11-23
Abstract: Группа изобретений относится к области косметологии, а именно к косметическим средствам для эффективного ухода за кожей с использованием альгинатов. Косметическая композиция для получения пластифицирующейся маски для кожи содержит (% мас.): альгинат натрия 5,0-12,0; диатомовая земля 3,0-15,0; сульфат кальция 2,0-7,0; натрия пирофосфат 0,3-1,5; гидратированный диоксид кремния 0,1-10,0; гидрогенизированное растительное масло и сополимер гидроксиэтилакрилата и акрилоилдиметилтаурата натрия 1-10,0; антиоксидант 0,01-1,0; биологически активные вещества 0,01-15,0; гидрофобная органическая среда - до 100%. Также раскрыт способ получения косметической композиции. Группа изобретений обеспечивает повышение равномерности нанесения маски на кожу лица. 2 н. и 8 з.п. ф-лы, 1 табл., 9 пр.
Patent UA-72753-C2 (UA)
Title: Appliance for control of the position of the blades with controlled angle of installation
IPC: F04D29/56
Filed: 2001-09-14
Abstract: A flexible control rod (20) is hinged with its first end part on a rotary ring (30) and is rigidly fixed with the other end part at the tail of the controlled blade (10). At that other end part the control rod is held with possibility of common turn without gaps at the tail element of the blade by means of holders (44, 52, 54). The means for hinged connection have a pin (24), this goes through the first through opening (22) arranged in the first end part of the control rod, and goes to the radial socket (28) in the rotary ring; at that the pin is held in its position by a stopper ring (34) equipped with windows (36) for that pin, and installed with possibility of displacement at the rotary ring. The fixation means have a control screw (40), this goes through the other through opening (38) arranged in the other end part of the control rod and goes to the reboring (42) of the tail element of the controlled blade.
Patent UA-57581-C2 (UA)
Title: Method for control of fuel level in float chamber of carburetor
Inventor: GRABAR IVAN GRYGOROVYCH
Filed: 2002-10-08
Abstract: A method for control of fuel level in float chamber of carburetor consists in the measuring and storing preliminarily, for all the known, possible according to design, values of fuel level in float chamber of carburetor of engine of given mark chosen as the standard, of respective values of the crankshaft rate of idle rotation till the engine stops after termination of fuel supply to the float chamber of carburetor. After that one measures the values of the same parameters for the fusel level being controlled in the float chamber of carburetor of the engine of the same mark. After that through comparison of the values of parameters obtained for the fuel level being controlled to the measured preliminarily and stored for the known fuel levels in float chamber of the engine chosen as the standard one as the level to be found of the fuel being controlled in the float chamber of carburetor one takes the values of the known level for which those parameters have been found the same.
Patent UA-59675-C2 (UA)
Title: Method of seismic exploration
Inventor: MARMALEVSKYI NAUM YANKELEVYCH
IPC: G01V1/00
Filed: 2002-11-14
Abstract: The proposed method of seismic exploration can be used in searching oil and gas deposits. The method implies exciting seismic vibrations, recording seismic signals by three-axis seismic receivers, which are installed in wells and at the original ground, processing the data obtained, and determining the probability parameters that characterize rock fissuring. The exploration is carried out by using two wells. One of the wells is located at the area with uniform rock strata, and the other well is located at the area with open fissured rocks. The method consists in exciting seismic vibrations along the radial profiles spaced through interval ?X ? 4 à 5?, where ? is the seismic wavelength, recording the seismic signals that correspond to reflected and through-pass longitudinal seismic vibrations, determining the amplitudes and the ratio between the amplitudes of the reflected and through-pass longitudinal seismic vibrations for each radial profile and each well, comparing the obtained data with the simulation data, determining the coordinates of the area with fissured rocks and the parameters that characterize the rock fissuring by using the said comparison results, determining the set of ground profiles corrected by the results of ground-based and well investigations, using the data of the preceding analysis of seismic vibrations for determining equidistant traces, determining, for each ground profile, the characteristics that define the change of the reflection coefficients for seismic vibrations and the derivative characteristics, comparing the data from the characteristics with the real data obtained for each well, and using the said comparison results for predicting the location, depth of burial, and area of the zone with fissured rocks. The present invention provides a possibility to increase accuracy in searching mineral resource deposits by seismic exploration.
Patent UA-73351-C2 (UA)
Title: Liquid formulation
IPC: A01N47/36
Filed: 2001-04-05
Abstract: The invention relates to liquid formulations (preparations) containing; a) one or more derivatives of polycarboxylic acids, and; b) one or more active substances from the group consisting of the ALS inhibitors.