baber/WOPTO huggingface dataset:
Patent IL-128336-A0 (IL)
Title: Biaromatic compounds and pharmaceutical and cosmetic compositions comprising them
IPC: A61K8/30
Filed: 1998-06-12
Abstract: The invention concerns bi-aromatic compounds of formula (I) in which Ar represents (a), Z being O or S, R1 is CH3, -CH2-O-R6, -OR6 or -COR7; R2 is -OR8, -SR8 or a polyether radical if in the latter case R4 is C1-C20alkyl and is in ortho or meta position relative to X-Ar; R3 is alkyl or R2 and R3 together form a cycle optionally interrupted by O or S; R4 is aryl radical; R5 is H, halogen, C1-C20 alkyl or -OR8; R6 is H, alkyl or -COR9; R7 is H, alkyl, -N(r')(r'') or -OR10; R8 is H, alkyl or -COR9; R9 is alkyl; R10 is H, C1-C20 alkyl, alkenyl, monohydroxyalkyl or polyhydroxyalkyl, aryl or aralkyl or a sugar residue, r' and r'' are H, alkyl mono- or polyhydroxyalkyl, aryl, an amino acid or sugar residue or together form a heterocycle, X represents a radical of formula (d) or (e) in which R11 is H or -OR6; R12 is H or alkyl; or R11 and R12 form an oxo radical, and the salts, optical and geometrical isomers of the compounds of formula (I).
Patent IL-141009-A0 (IL)
Title: N-substituted azabicycloheptane derivatives, production and use thereof
IPC: C07D417/06
Filed: 1999-07-20
Abstract: Compounds of the formula I:in which R1, R2, R3 and R4 have the meanings stated in the description, are described.The novel compounds are suitable for controlling diseases.
Patent IL-142428-A0 (IL)
Title: Novel g protein-couple receptor proteins, dna's thereof and ligands to the same
IPC: A61P15/06
Filed: 1999-10-26
Abstract: The present invention relates to rat cerebellum-derived and human brain-derived G protein coupled receptor proteins or salts thereof, their partial peptides, amides, esters or salts thereof, ligands to the same, a method/kit for screening compounds that alter the binding property between the ligands and the G protein coupled receptor proteins, compounds obtained by the screening or salts thereof, and antibodies to the G protein coupled receptor proteins. The rat cerebellum-derived and human brain-derived G protein coupled receptor proteins and the like are useful: (1) for determination of a ligand to the receptor protein of the present invention (ligand peptide of the present invention) (agonist), (2) as an agent for the prevention and/or treatment of diseases associated with dysfunction of the G protein coupled receptor protein of the present invention, (3) as a genetic diagnostic agent, (4) for quantification of a ligand to the G protein coupled receptor protein of the present invention, (5) for screening of a compound (agonist, antagonist, etc.) that alters the binding property between the G protein coupled receptor protein of the present invention and a ligand (ligand peptide of the present invention), (6) as a agent for the prevention and/or treatment of various diseases, comprising a compound (agonist, antagonist, etc.) that alters the binding property between the G protein coupled receptor protein of the present invention and a ligand (ligand peptide of the present invention), (7) for quantification of the receptor protein, its partial peptide or salts of the present invention, (8) for neutralization by antibodies to the receptor protein, its partial peptide or salts of the present invention and (9) for preparation of a non-human animal bearing the DNA encoding the G protein coupled receptor protein of the present invention.
Patent IL-145678-A0 (IL)
Title: Semiconductor wafer processing system with vertically-stacked process chambers and single-axis dual-wafer transfer system
IPC: H01L21/02
Filed: 2000-04-21
Abstract: A semiconductor wafer processing system including a multi-chamber module having vertically-stacked semiconductor wafer process chambers and a loadlock chamber dedicated to each semiconductor wafer process chamber. Each process chamber includes a chuck for holding a wafer during wafer processing. The multi-chamber modules may be oriented in a linear array. The system further includes an apparatus having a dual-wafer single-axis transfer arm including a monolithic arm pivotally mounted within said loadlock chamber about a single pivot axis. The apparatus is adapted to carry two wafers, one unprocessed and one processed, simultaneously between the loadlock chamber and the process chamber. A method utilizing the disclosed system is also provided.
Patent IL-145883-A0 (IL)
Title: System and method for modeling genetic, biochemical, biophysical and anatomical information
IPC: G06F17/30
Filed: 2000-02-08
Abstract: Genetic, biochemical, biophysical and anatomical information is integrated at the cellular and subcellular level. At least one database containing biological information is used to generate at least one data structure having at least one attribute associated therewith. An interface interactively views and links together attributes of a plurality of data structures to create at least one hierarchical description of subcellular and cellular function. A computational engine generates at least one mathematical equation from the hierarchical description. Genetic information is accessed, tabulated and combined with functional information on the biochemical and physiological role of gene products. Computational models of genetic, biochemical and biophysical processes within cells are automatically formulated, solved and analyzed based on combination of genetic and functional information adduced. A dynamic tool is thereby provided for achieving objectives, such as increased understanding of biological processes, identification of new drug targets for therapeutic intervention and predictions involving the outcome of drug screening.
Patent IL-147259-A0 (IL)
Title: Use of nanoscale sterols and sterol esters
IPC: A61K31/575
Filed: 2000-06-16
Abstract: The invention relates to the use of nanoscale sterols and/or sterol esters with particle diameters of 10 to 300 nm as food additives and as active substances for the production of hypocholesterolemic agents. The particular fineness of the particles promotes more rapid absorption by the blood serum after oral ingestion by comparison with conventional sterols and sterol esters.
Patent IL-148768-A0 (IL)
Title: Laryngeal mask with large-bore gastric drainage
IPC: A61M16/04
Filed: 2000-10-09
Abstract: An artificial airway device for use in unconscious patients comprises a laryngo-pharyngeal mask including an expandable masking ring. The expandable mask sealingly surrounds the laryngeal inlet when expanded to obstruct communication between the laryngeal inlet and oesophagus. One or more airway tubes connected to the mask provide for fluid flow to a portion of the mask facing the laryngeal inlet when said mask sealingly surrounds the laryngeal inlet. A gastro-tube connected to the mask provides a fluid flow-path to the mask when the mask sealingly surrounds the laryngeal inlet. The distal end of the gastro tube passes through the masking ring at its narrower distal region where, when installed in a patient, it abuts against the oesophagus; and the distal portion of the gastro-tube flattens when the mask is deflated to facilitate smooth passage behind the larynx during insertion through the mouth and throat of the patient.
Patent IL-150757-A0 (IL)
Title: 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
IPC: A61K31/4025
Filed: 2001-02-21
Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of general formula (B. geometrical isomers, enantiomers, diastereoisomers, mixtures of each of these and pharmaceutically acceptable salts thereof. whereinR<sup>1</sup> is methyl,R<sup>2</sup> and R<sup>4</sup> are hydrogen.R<sup>3</sup> is alkyl or haloalkenyl, andX is -COOH. -COOMe or -COOEt.
Patent IL-154823-A0 (IL)
Title: Mixing high temperature gases in mineral kilns
IPC: C04B7/44
Filed: 2001-09-12
Abstract: A method is described for reducing NO x  emissions and improving energy efficiency during mineral processing in a rotary kiln. The method comprises injection of air with high velocity/high kinetic energy into the kiln to reduce or eliminate stratification of kiln gases. The method can be applied to mix gases in a rotary kiln vessel or in a preheater/precalciner vessel.
Patent IL-158902-A0 (IL)
Title: Chromate free, waterborne epoxy corrosion resistant primer
IPC: C09D5/00
Filed: 2003-11-17
Abstract: The invention provides a waterborne epoxy corrosion resistant primer comprising a waterborne epoxy, a curing agent, and a non-chromate containing corrosion-inhibiting pigment.
Patent IL-165759-A0 (IL)
Title: Split vane flow blocker
IPC: F01D25/30
Filed: 2004-12-14
Abstract: A gas path flow blocker comprising a plurality of vanes (21) each comprising a forward portion (25) and an aft portion (23) defining a plurality of gas paths, a forward ring (15) comprising a central axis (19) about which is circumferentially disposed the plurality of forward portions (25), and an aft ring (17) disposed about the central axis (19) about which is circumferentially disposed the plurality of aft portions (23) wherein the forward ring (15) and the aft ring (17) are moveable with respect to each other to at least partially block the flow of a gas through the gas paths. <IMAGE>
Patent IL-175253-A0 (IL)
Title: A process for preparing pyrrole derivatives
IPC: C07D207/34
Filed: 2006-04-27
Abstract: The present invention relates to an improved synthesis of pyrrole capping group precursors.
Patent IL-175382-A0 (IL)
Title: Anastomotic ring applier with inflatable members
IPC: A61F2/958
Filed: 2006-05-02
Abstract: A surgical instrument (10) comprises a handle (19) connected to a shaft (15) and a pair of inflatable members (30,32). The shaft includes conduits (96) for communicating a pressurized medium to the inflatable members and an insufflation tube. The handle includes a port for communicating a pressurized medium to the conduits and a port for communicating a pressurized medium to the insufflation tube. After an anastomotic ring (14) has been deployed, the shaft may be positioned such that an inflatable member is positioned within each of the lumens joined by the anastomosis, such that an inflatable member is located on each side of the anastomosis. The inflatable members may be inflated to provide a seal in each of the lumens. With each of the lumens sealed by the inflatable members, the anastomosis site may be insufflated through the insufflation tube to leak or pressure test the anastomosis.
Patent IL-180671-A0 (IL)
Title: Aerated food products containing hydrophobin
IPC: A23L33/18
Filed: 2007-01-11
Abstract: An aerated food product is provided which includes hydrophobin. Also provided is the use of a hydrophobin in a method of inhibiting bubble coarsening in aerated food products.
Patent IL-204732-A0 (IL)
Title: 2' - fluoro - 2' - deoxytetrahydrouridines as cytidine deaminase inhibitors
Filed: 2010-03-25
Abstract: The present invention provides certain tetrahydrouridine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of making and using such compounds.
Patent RO-129929-A0 (RO)
Title: Method and installation for parachuting a logic unitary active equipment for special and complex fast control
Inventor: RÎNEA TIBERIU EMIL ILIE
IPC: F42B15/01
Filed: 2014-06-27
Abstract: The invention relates to a method and an installation for parachuting a logic unitary active equipment of special and complex fast control meant to open the short and fast parachute for low-altitude drops by reverse launching for aircraft rescue. The claimed method consists in that the parachute is self-launched detecting the damage by movements and accelerations, guiding the landing and selecting the method adequate to the situation, the ballistic parachute being apparently reversely opened, and then vertically reoriented by the traction of the falling object, so that the parachute appears already opened beside the object, the launching of the bag being possible through the rotor in a synchronised manner with helicopter rotor, the parachute being anchored to the rotor, unwinding the cable from the bag in a tensioned and controlled manner above the moving blades. The claimed installation comprises two bags () for the parachutes that are installed in stand-by on the aircraft, each bag having two parachutes with two power stages, the first stage consisting in braking and orienting the aircraft, the second stage in additionally braking it, in cooperation with the first stage, and for launching the parachute bag () and passing it above the rotor, and in the point which has been selected as the most favourable, each bag () is installed on a launching minigun () by means of which the bag mass is detached from the aircraft and quickly and precisely launched in synchronism with the rotation of blades, the minigun () being oriented under an angle () adjustable depending on the situation, each bag () being provided with a remotely controlled carrying rocket () for transportation, with a possibility of correction of the initial launching direction while moving and with a limited propulsion at the finish of the estimated path and control stop, being guided in a programmed manner and assisted logically on a prolonged semi-circular path, as the case may be, while the path is traveled, the said path being generated by the rocket () which stretches the anchoring cable () above the blades of the main rotor, and having a radius limited by the momentary length of the anchoring cable () stretched in a tensioned manner.
Patent RO-130306-A0 (RO)
Title: Clothing assembly for medical applications
Inventor: BREZULIANU ADRIAN
IPC: A61B5/0205
Filed: 2014-12-18
Abstract: The invention relates to a clothing assembly which includes several sensors meant to acquire physiological data of the clothing assembly wearer, to store and process the same, at a local level, and to remotely transmit the results obtained after processing. According to the invention, the clothing assembly consists of a coat () and a pair of trousers () having included a system () for monitoring the physiological parameters, as follows: the coat sleeves are provided with cuffs with electrodes (), the trousers are provided with ankle pads with electrodes (), each cuff and ankle pad being connected, by means of an electric conductor (), to an acquisition, processing and communication unit () whereto there are also connected: a pulse oximeter (), a device () for measuring arterial pressure and a device () for monitoring movements.
Patent RO-132045-A0 (RO)
Title: Highly felxible and malleable composite product for cross-linked polyethylene pipes to be used in underfloor heating
Inventor: TRANDAFIR CRISTIAN-COSTEL
IPC: C08L23/04
Filed: 2017-02-09
Abstract: The invention relates to a composite product for cross-linked polyethylene pipes to be used in underfloor heating. According to the invention, the product is based on high-density polyethylene modified by in-melt alloying with 3...15% polyethylene/styrene-diene block-copolymer composite and partially cross-linked with 0.3...0.6% organic peroxide, having a fracture elongation of 510...780% and an elasticity modulus of 480...622 MPa.
Patent RO-133817-A0 (RO)
Title: Process for preparing antioxidant collagen peptides from freshwater fish skin
Inventor: CRĂCIUNESCU OANA
IPC: A61K8/65
Filed: 2018-11-08
Abstract: The invention relates to a process for preparing antioxidant peptides to be used in the cosmetic industry. According to the invention, the process consists in the extraction of collagen from freshwater fish skin having a content of 1 ... 2% dry matter, as a solution with a collagen content of 75 ... 90% and a pH of 5...6.5, which is subjected to enzymatic hydrolysis by treatment with 5 to 10 volumes of Tris buffer 0.05 M containing sodium chloride, calcium chloride and/or 0.5% SDS, in which microbial proteases, such as type I collagenase, proteinase K and a mixture thereof have been dissolved in an enzyme : substrate ratio of 1:25 ... 1:50, at 37 ... 60°C, for 6 ... 24h, after which the solutions are subjected to ultrafiltration, the filtrate is passed through the filtering units of 3 kDa, concentrated and lyophilized, resulting in a water-soluble powder of collagen peptides with a controlled molecular mass of 3...10 kDa and a purity higher than 85%.
Patent AP-2002002679-A0 (AP)
Title: Novel polymorph V of torasemide.
Inventor: FILIC DARKO
IPC: A61P11/06
Filed: 2000-09-25
Abstract: The invention relates to a novel polymorph V of torasemide, to a process for its preparation, to its use as a raw material for the preparation of crystalline modifications I and III of torasemide, to amorphous torasemide modifications and to pharmaceutically acceptable salts of torasemide, to pharmaceutical forms containing the said novel polymorph V of torasemide as the active ingredient as well as to its use.
Patent IE-910081-A1 (IE)
Title: The use of DNA-dependent RNA polymerase transcripts as¹reporter molecules for signal amplification in nucleic acid¹hybridization assays
IPC: C12Q1/68
Filed: 1991-01-10
Abstract: A polydeoxynucleotide construct is disclosed for use, in conjunction with a DNA-dependent RNA polymerase, as a signal amplifier in nucleic acid hybridization assays. The construct contains a recognition sequence for a target oligonucleotide, a promoter sequence for a DNA-dependent RNA polymerase, and a polymerase template. A method of use for this construct in hybridization assays is also disclosed. The method involves formation of a hybridization complex comprising the construct and the target sequence; addition of a polymerase which is specific for the promoter in the construct; and quantification of the resulting RNA transcripts.
Patent CU-21680-A1 (CU)
Title: Metodo para purificar soluciones azucaradas
Inventor: GONZALEZ RELOBA EMIGDIO
Filed: 1984-08-16
Abstract: La invención se relaciona con la industria azucarera, y más específicamente con la purificación y decoloración simultánea de soluciones azucaradas. El método consiste en el tratamiento de la solución azucarada por ácido fosfórico y cal, o por Ca3(PO4)2 previamente formado y posterior separación del precipitado por flotación después de aereación y adición de una pequena cantidad de floculante auxiliar de poliacrilamida, CARACTERIZADO porque para aumentar el efecto de decoloración, mejorar la calidad de la solución y disminuir el consumo de poliacrilamida y de ácido fosfórico y cal o Ca 3 (PO4)2 y también disminuir las pérdidas de sacarosa, a la solución antes de fosfatar se anade anionito hidrosoluble en base de aminoésteres de ácido metacrílico en cantidad de 0,005 - 0,120% con respecto a la sustancia seca en la solución azucarada.
Patent IE-910108-A1 (IE)
Title: Stabilised gel system and production thereof
IPC: C11D3/12
Filed: 1991-01-14
Abstract: A stabilised gel system for supporting finely divided particulate matter in suspension comprises a hydrosol of silicic acid stabilised by entanglement with micelles of a tenside. Such a stabilised gel system can be used as the basis for a liquid built detergent composition or for an abrasive preparation.
Patent IE-910664-A1 (IE)
Title: New aryl- and heteroarylethenylene derivatives and process for their preparation
Inventor: BUZZETTI FRANCO
IPC: C07C59/54
Filed: 1991-02-27
Abstract: A compound of general formula (I) <CHEM>  wherein   Y   is a bicyclic ring system chosen from (B), (A), (E), (F) and (G) <CHEM>   R   is <CHEM>   R1   is hydrogen, C1-C6 alkyl or C2-C6 alkanoyl; R2   is hydrogen, halogen, cyano or C1-C6 alkyl; n   is zero or an integer of 1 to 3: n is zero or an integer of 1 to 3 when Y is a ring system (A), whereas it is zero, 1 or 2 when Y is a ring system (B), (E), (F) or (G); and the pharmaceutically acceptable salts thereof; and wherein each of the substituents R, OR2 and R2 may be independently on either of the aryl or eteroaryl moieties of the bicyclic ring system (A), (E), (F) and (G), whereas only the benzene moiety may be substituted in the bicyclic ring (B).   The compounds of the present invention possess specific tyrosine kinase inhibiting activity. Hence they can be useful in the treatment of cancer and other pathological proliferative conditions.
Patent MA-19903-A1 (MA)
Inventor: FRANS ELISABETHA VAN GESTEL
IPC: A01N37/40
Filed: 1983-09-16
Abstract: The use of salicylanilides of the formula <CHEM> as insect chemosterilants and insect chemosterilant compositions containing at least one compound of formula (I) as an active ingredient.
Patent MA-20163-A1 (MA)
Inventor: ROBERT BENET
IPC: G01N1/10
Filed: 1984-07-03
Abstract: Apparatus for withdrawing liquid samples from liquid/solids media, e.g., phosphoric acid slurries, for the downstream analysis thereof, is comprised of (i) means adapted for insertion into a liquid/solids medium to selectively separate and receive a liquid fraction therefrom, (ii) a liquid storage first chamber in communicating relationship with said separating and receiving means (i), (iii) a liquid sample receiving second chamber in independent, parallel communicating relationship with said separating and receiving means (i) and which comprises means for exteriorly discharging sample contained therein, and (iv) means permitting the filling or emptying of said second chamber (iii) independently of said first chamber (ii).
Patent MA-24966-A1 (MA)
Title: Procede pour la preparation de sels acides de trovafloxacine
Inventor: TIMOTHY NORRIS
IPC: C07D471/04
Filed: 1999-09-01
Abstract: L'INVENTION CONCERNE UN PROCÉDÉ POUR LA PRÉPARATION D'UN SEL ACIDE DE TROVAFLOXACINE DE FORMULE, DANS LAQUELLE ZH REPRÉSENTE UN ACIDE MINÉRAL. ELLE CONCERNE ÉGALEMENT LES INTERMÉDIAIRES UTILISÉS POUR CETTE PRÉPARATION.  APPLICATION  :  UTILISATION DE CES COMPOSÉS POUR LE TRAITEMENT D'INFECTIONS BACTÉRIENNES.
Patent MA-26035-A1 (MA)
Inventor: RALF LAVEN
IPC: C08F291/00
Filed: 1999-10-12
Abstract: The invention relates to a process for preparing crosslinkable polymers containing silane groups having at least one hydrolyzable radical by free-radical-initiated grafting of the base polymers with an olefinically unsaturated silane having at least one hydrolyzable radical, wherein the grafting is carried out in the presence of(a) an alkylsilane of the formula I, whereR1 is a monovalent hydrocarbon radical having from 1 to 33 carbon atoms or a divalent hydrocarbon radical having from 4 to 24 carbon atoms,R2 is a hydrocarbon radical having from 1 to 10 carbon atoms,X are identical or different hydrolyzable radicals,n is 0, 1 or 2 andm is 1 or 2 and/or(b) a fluoroalkylsilane of the formula whereR3 is a fluoroalkyl radical,R4 is an alkyl radical andX is a hydrolyzable radical,x is an integer from 1 to 3,y is 0, 1 or 2 andz is an integer from 1 to 3, with the proviso that the sum x+y+z=4.
Patent MA-27324-A1 (MA)
Inventor: ITO MASASHI
IPC: A61K35/12
Filed: 2005-01-17
Abstract: The present invention relates to primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells. This invention provides cells suitable for gene therapy, which can replace bone marrow cells and liver cells used for conventional  ex vivo  gene therapy. The present invention established methods for transferring foreign genes into primary cultured adipocytes, which are suitable for ex vivo gene therapy; can be easily collected and implanted; and can be removed after implantation. Specifically, the present invention established these methods that use retroviral vectors. The present invention also established primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells.
Patent MA-20150136-A1 (MA)
Title: Dispositif d'anti nidification de cigognes
Inventor: SOBH MOHAMED
IPC: A01M29/00
Filed: 2013-10-01
Abstract: La présente invention concerne un dispositif d'anti nidification de cigognes qui a plusieurs méfaits sur les pylônes touchés. Il peut être installé notamment sur les pylônes destinés pour abriter les antennes télécoms ou bien sur les pylônes de transport d'énergie électrique. Ce dispositif ne présente aucun danger ni sur la vie des humains ni oiseaux, nous pouvons dire qu'il s'agit d'une solution verte.