baber/WOPTO huggingface dataset:
Patent AP-764-A (AP)
Title: Methods for inducing Tcell tolerance to a tissue or organ graft.
Inventor: NOELLE RANDOLPH J
IPC: A61K35/14
Filed: 1995-04-25
Granted: 1999-09-16
Abstract: Methods for inducing T cell tolerance to a tissue or organ graft in a transplant recipient are disclosed. The methods involve administering to a subject: 1) an allogeneic or xenogeneic cell which expresses donor antigens and which has a ligand on the cell surface which interacts with a receptor on the surface of a recipient T cell which mediates contact-dependent helper effector function; and 2) an antagonist of the receptor which inhibits interaction of the ligand with the receptor. In a preferred embodiment, the allogeneic or xenogeneic cell is a B cell, preferably a resting B cell, and the molecule on the surface of the T cell which mediates contact-dependant helper effector function is g?39. A preferred gp39 antagonist is an anti-gp39 antibody. The allogeneic or xenogeneic cell and the gp39 antagonist are typically administered to a transplant recipient prior to transplantation of the tissue or organ. The methods of the invention can be used to induce T cell tolerance to transplants such as liver, kidney, heart, lung, skin, muscle, neuronal tissue, stomach and intestine. A method for treating diabetes comprising administering to a subject allogeneic or xenogeneic cells expressing donor antigens, a gp39 antagonist and pancreatic islets is also disclosed. The invention also covers a. method for inducing T cell tolerance to an antigen-.presenting cell in a human recipient comprising administering an effective amount of a gp39 antagonist. Also covered is a combination of allogeneic or xenogeneic cell which expresses at least one donor antigen for use in various methods of treatment.
Patent AT-A5332002-A (AT)
Inventor: MALLE MANFRED ING
IPC: G05G1/30
Filed: 2002-04-05
Abstract: A pedal system for bicycles includes a shoe insert, which can be fastened to the exterior of a shoe, having a detent element. The pedal system also includes a pedal, which can be fastened to the bicycle, can rotate about an axis, and which has a seat for accommodating the detent element. The detent element can be locked counter to elastic force inside the seat and can be released therefrom by executing a rotating movement. The seat for the detent element is formed between two seat parts, which are rotationally symmetrical with regard to the pedal axis and which can be displaced away from one another counter to elastic force in the direction of the pedal axis.
Patent AU-1044183-A (AU)
Title: A method for recovering useful products from waste products obtained when manufacturing aluminium hydroxide
Inventor: LENNART BERGLUND HANS ARNE
IPC: C01B33/26
Filed: 1982-12-21
Abstract: PCT No. PCT/SE82/00434 Sec. 371 Date Aug. 31, 1983 Sec. 102(e) Date Aug. 31, 1983 PCT Filed Dec. 21, 1982 PCT Pub. No. WO83/02444 PCT Pub. Date Jul. 21, 1983.The invention relates to a method for recovering useable products from waste products deriving from the manufacture of aluminium fluoride on the basis of aluminium hydroxide and fluosilicic acid. Mother liquors and washing water from a scrubber in said process, which solutions contain aluminium, silica, fluorine, and phosphorous is reacted in a first step with sodium ions at pH 2-3, and a temperature of 50 DEG -100 DEG  C. to give a precipitate of sodium fluoroaluminate, which is isolated. The filtrate from said first step can be reacted with the silica waste product obtained in the above mentioned aluminium fluoride manufacture.
Patent AU-1055300-A (AU)
Title: Diphosphines
Inventor: BROWN JOHN MICHAEL
IPC: C07C233/47
Filed: 1999-10-29
Abstract: A non-symmetrical diphosphine of the formula R<1>R<2>P-(Z)-PR<3>R<4 >wherein Z represents a chain of 2 to 4 carbon atoms which may be substituted, which chain may be saturated or unsaturated, and R<1>, R<2>, R<3 >and R<4>, which may be the same or differ, are aliphatic, aromatic or heteroaromatic groups attached to the phosphorus by carbon, nitrogen, oxygen or sulphur such that each phosphorus atom and its substituents independently form a single enantiomer.
Patent AU-1093692-A (AU)
Title: Disubstituted ureas and thioureas derivatives
Inventor: COZZI PAOLO
IPC: C07C275/32
Filed: 1992-02-12
Abstract: The invention provides new ureas and thioureas derivatives of general formula (I) <CHEM>  wherein  m is zero, 1 or 2;  n is 1, 2 or 3;  Q is oxygen or sulphur;  X and Y, being the same, are oxygen or sulphur;     A is   a) a C1-C10 saturated or unsaturated, branched or unbranched hydrocarbon chain, unsubstituted or substituted by 1 to 4 substituents independently chosen from halogen, C1-C6 alkyl, trihalo-C1-C3 alkyl and C1-C6 alkoxy; b) a C3-C7 cycloalkyl ring unsubstituted or substituted by 1 to 4 substituents independently chosen from halogen, C1-C6 alkyl, trihalo-C1-C3 alkyl and C1-C6 alkoxy; c) an aryl group unsubstituted or substituted by one to four substituents independently chosen from halogen, C1-C6 alkyl, trihalo-C1-C3 alkyl, hydroxy, C1-C6 alkoxy, C1-C6 alkylthio, C1-C6 alkylsulfonyl and C1-C4 di-alkylamino; d) an aryl group substituted by two adjacent substituents forming a methylenedioxy group and optionally by 1 to 3 substituents as defined above under c); or e) an aryl group substituted by an imidazolyl group, in its turn optionally substituted by C1-C4 alkyl; each of R1 and R2, independently, is C1-C6 alkyl; or R1 and R2, taken together, are a C2-C4 alkylene chain in which each carbon atom can be optionally substituted by 1 or 2 substituents independently chosen from halogen and C1-C4 alkyl; B is an aryl group unsubstituted or substituted by 1 to 4 substituents independently chosen from halogen, C1-C6 alkyl, trihalo-C1-C3 alkyl, C1-C6 alkoxy, C1-C6 alkylthio, and C1-C6 alkylsulfonyl; and the pharmaceutically acceptable salts thereof, which are useful as therapeutic agents such as for the prevention of coronary heart disease and as antidyslipidaemic agents.
Patent AU-1138399-A (AU)
Title: Protein production in transgenic alfalfa plants
Inventor: VEZINA LOUIS-P
IPC: C12N15/09
Filed: 1998-11-10
Abstract: <P>PROBLEM TO BE SOLVED: To provide a transgenic plant for producing a transgenic protein stably.  <P>SOLUTION: A method for stably producing an extractable protein includes the following processes: (a) a process of selecting an alfalfa gene type showing a negligible proteinase activity for at least 3 hrs in an extract; (b) a process of transforming at least one alfalfa plant having the gene type selected in the process (a) with a vector containing a gene encoding the protein to produce at least one transformed alfalfa plant; (c) a process of confirming the presence of the gene in the above at least one transformed type alfalfa plant; (d) a process of growing the at least one transformed type alfalfa plant to produce such the protein; and (e) a process of extracting the protein from the plant.  <P>COPYRIGHT: (C)2009,JPO&INPIT
Patent AU-1188995-A (AU)
Title: Method of treatment of prostate cancer
Inventor: BRANDES LORNE J
IPC: A61K33/243
Filed: 1994-12-07
Abstract: Prostate cancer particularly hormone-unresponsive metastatic prostate cancer, is treated by cyclophosphamide or other normally substantially inactive agent. Potentiation of the anti-cancer activity and amelioration of cyclophosphamide-associated toxicity is achieved by an initial intravenous infusion of DPPE over an approximately one hour period prior to cyclophosphamide treatment.
Patent AU-1246295-A (AU)
Title: Multilayer article including a vulcanised elastomer directly combined with a thermoplastic
Inventor: CERF MARTINE
IPC: B29C48/15
Filed: 1994-12-13
Abstract: Multilayered article including a functionalized and vulcanized elastomer adherent by itself to a thermoplastic chosen from polyamides, PBT, mixtures containing polyvinylidene fluoride and ethylene/vinyl alcohol and ethylene/tetrafluoroethylene copolymers.Composite tubular article made up of an outer sheath of vulcanized elastomer adherent to a hydrocarbon-barrier thermoplastic or associated with an inner layer for producing imperviousness.
Patent AU-1267002-A (AU)
Title: Gel for electrophoresis
Inventor: BEN-ASOULI YITZHAK
IPC: G01N27/447
Filed: 2001-10-29
Abstract: The present invention is directed to a solidified hybrid gel for use in an electrophoresis process, having a solidified first gel portion juxtaposed with a solidified second gel portion. The first gel portion is capable of accommodating therein one or more samples for electrophoresis after said first gel portion is in solidified form, and the second gel portion is adapted for enabling an electrophoresis process to be applied to such a sample that may be accommodated in said first gel portion. Thus, the hybrid gel may be provided in a precast form to users, ready for use. The invention is also directed to methods for providing such a gel, apparatuses for accommodating such a gel, and methods for carrying out electrophoresis on a sample comprised in such a gel.
Patent AU-1354899-A (AU)
Title: Cathodoluminescent screen with a columnar structure, and the method for its preparation
Inventor: GIVARGIZOV EVGENY INVIEVICH
IPC: H01J29/18
Filed: 1998-10-26
Abstract: A cathodoluminescent mosaic screen on a light-transparent substrate wherein the light-emitting components of the screen are implemented as light-guiding single-crystalline columns. A method for preparation of the screen by vapor deposition of the luminescent material onto the substrate coated by a localized liquid phase has been proposed.
Patent AU-1443188-A (AU)
Title: Article of ceramic material and production thereof
IPC: C04B35/58
Filed: 1988-04-08
Abstract: A process for the production of a shaped article of a ceramic material in which a composition comprising particulate ceramic material and a liquid medium is shaped, the liquid medium is removed from the shaped composition, and the composition is heated to sinter the particles of ceramic material in which the composition is subjected to high shear mixing such that in the shaped article which is produced the mean maximum size of flaw is less than 25 microns. Also, a shaped article of sintered particulate ceramic material in which the mean maximum size of flaw is less than 25 microns and in which the minimum dimension of the shaped article is in excess of 0.1 mm.
Patent AU-1533701-A (AU)
Title: Hollow-needle devices
Inventor: JEFFREY PETER
IPC: A61M5/50
Filed: 2000-11-23
Abstract: Hollow-needle device (100) comprises a hollow plunger (105), a body part affording a cylindrical chamber (101) within which the plunger (105) is sealingly slidable, a needle-carrying hub (120) for automatic retraction into the plunger (105), and a closure (130) for the plunger (105). The closure (130) comprises a member (131) normally in sealing relation with end-adjacent internal provision (133) of the hollow plunger (105) but disengageable therefrom and bodily movable into the hollow plunger (105) by localised first engagement (135) of the member (131) at or near end of contents expression stroke of the plunger (105).
Patent AU-1541701-A (AU)
Title: Direct screening method
Inventor: HOLT LUCY JESSICA
IPC: G01N33/566
Filed: 2000-12-04
Abstract: The invention concerns a method for screening a repertoire of polypeptides to identify one or more members thereof which interact with one or more target molecules, comprising: a) immobilising the target molecule(s) on a support; b) arranging a plurality of nucleic acid molecules encoding the repertoire of polypeptides in an array; c) juxtaposing the target molecule(s) and the arrayed nucleic acid molecules; d) expressing the arrayed nucleic acid molecules to produce the polypeptides such that said polypeptides come into contact with the target molecules(s) on the support and a subset of the polypeptides interacts with the target molecules; and e) detecting the interaction of the polypeptides with the target molecules on the support. The invention also provides a high density antibody array consisting of thousands of different polypeptide features, spatially arranged on a solid support for screening against different target ligands
Patent AU-1565599-A (AU)
Title: A method for the prevention and treatment of stunned myocardium
Inventor: HAIKALA HEIMO
IPC: C07D215/22
Filed: 1998-12-11
Abstract: A method for the prevention and treatment of stunning of the heart subsequent to ischemia-reperfusion is described. The method comprises administering a therapeutically effective amount of a phospholamban inhibitor to a patient. Phospholamban inhibitors relieve the inhibitory effect of phospholamban on cardiac sarcoplasmic reticulum Ca2+-ATPase.
Patent AU-1649483-A (AU)
Title: Allyloxy- and allylthio-2,3,4,5 tetrahydro 1h-3-benzazepines
Inventor: DEMARINIS ROBERT MICHAEL
IPC: C07D223/16
Filed: 1983-07-01
Abstract: Compounds of the structural formula: 
<CHEM>
 in which:
 R is hydrogen or a lower alkyl of 1-6 carbons; and
 R<1>, R<2> and R<3> are allyloxy, allylthio, halo or hydrogen, with the proviso that one of R<1>, R<2> and R<3> is allyloxy or allylthio; or a pharmaceutically acceptable acid addition salt thereof, a process for their preparation and their application as  alpha 2-antagonists and as intermediates for preparing  alpha 2-adrenergic affinity resins.
Patent AU-1677000-A (AU)
Title: High speed continuous casting device and relative method
Inventor: POLONI ALFREDO
IPC: B22D11/14
Filed: 2000-01-06
Abstract: High speed continuous casting device and method, comprising an ingot mold provided with a crystalliser having side-walls between which the product as it cools is suitable to take shape, the product then being sent to a guide, containing and possibly pre-rolling assembly located downstream of the ingot mold and cooperating with secondary cooling, and a system of primary cooling associated with the side-walls, the crystalliser having a longitudinal development with a radius of curvature ("R") having a value at least five times more than the first radius of curvature of the product in the secondary cooling zone located at the outlet of the crystalliser, wherein the length (L) of the walls is more than 1050 mm, so that a progressive and gradual deformation of the product being formed is obtained which prevents tensions, inner cracks and surface lesions from forming thereon.
Patent AU-1712592-A (AU)
Title: Switch for grooved rails
IPC: E01B7/06
Filed: 1992-05-22
Abstract: The switch consists of a profiled cradle forming the housing for a moveable deviation switch rail (18) and of a shaped body (20) made by machining by cutting. In order to reduce the machining waste and improve the reliability of the switch rail operation, the body (20) is bolted between a stock-rail (22) and an opposite rail (24), both being without their adjacent foot over the whole length of the body (20), and the upper surface of the body (20) supporting the moveable part of the switch rail (18) is profiled in such a way as to present flat bearings (28) for supporting the switch rail (18) alternating with notches (30) machined in the body (20). <IMAGE>
Patent AU-1820595-A (AU)
Title: Programmable materials
Inventor: MICHAEL JOSEPH
IPC: A63H33/04
Filed: 1995-03-03
Abstract: Programmable material is a collection of substantially cubic shaped bricks called monomers that move relative to each other under computer control to sculpt engineering structures (5) and mechanisms (6) (walking machine) illustrated in the figure. The monomers have features to lock to other monomers and slide relative to other monomers without separating. The monomers are fault tolerant against damage; functional monomers move faulty monomers and replace them with functioning clones. Movement of monomers is broken down systematically into streamers, gateways, highways and reservoir methods to obtain individual monomer movement paths required to synthesise a structure. Specialised monomers can carry tools which together with synthesis of custom structures create custom machines.
Patent AU-1849888-A (AU)
Title: System for data transmission
Inventor: PAS LEO VAN DE
IPC: G01F23/62
Filed: 1988-06-29
Abstract: System for the transmission of data in a measuring instrument in which a measuring device is being introduced in a medium in order to measure specific properties thereof and with which these measuring data are being transmitted, characterized in that it primarily consists of the combination of an autonomous and active measuring device (3); a freely movable electrically conductive element (4) with which the measuring device (3) is connected; a signal receiving unit (9) where through or along which, the electrically conductive element (4), without making physical or galvanic contact, can move freely; a signal processing unit '12) which is electrically connected with the signal receiving unit (9) and a direct or indirect electric connection between the electrically conductive and freely movable element (4) and the medium to be tested.
Patent AU-1879001-A (AU)
Title: Injection device and propulsion system therefor
Inventor: NERACHER ARNOLD
IPC: A61M5/46
Filed: 2000-12-21
Abstract: A propulsion system suitable for a single-use or a multi-use needleless injection device comprises a container and a source of potential energy for propelling a fluid (2) with sufficient pressure through an orifice to create a jet enabling subcutaneous or intracutaneous delivery of the fluid, the source of potential energy primarily in the form of a compressible substance (7) under pressure within the container. The compressible substance is preferably a polysiloxane or vulcanized silicon rubber.
Patent AU-1905492-A (AU)
Title: Improved volumetric batcher, particularly for chamomile flowers to be packed in filter-bags
IPC: B65B1/36
Filed: 1992-05-19
Abstract: An improved volumetric batcher particularly suitable for a dosed feeding of a dishomogeneous and scarcely slidable as well as extremely fragile product, such as chamomile flowers, to be introduced in filter-bags. Several batching units placed side by side, provide operation with high-speed packing machines. Fed by a single container is the bottom of the container screw-feeders are provided to push the product in to a corresponding vertical loading conduit. A pneumatic piston in the loading conduit compress to a product in the batching chamber which is aligned with a hole passing through a fixed plate which supports the batcher. The batching chamber is located inside a mobile second plate of the batcher. When the second plate is in a loading position, the batching chamber is aligned with the hole and the loading circuit and in as opposed discharging position, the batching chamber is aligned with a second hole is the fixed supporting first plate, which hole serves for the passage of an ejecting piston, and a discharging hole of a fixed underlying third plate of the batcher.
Patent AU-1939988-A (AU)
Title: Method of producing cystatin c or modifications hereof and dna-sequence for use when carrying out the method
Inventor: GRUBB ANDERS
IPC: A61P31/12
Filed: 1988-05-20
Abstract: Cystatin C or a modified cystatin C is produced biosynthetically by culturing microorganisms or cells into which cDNA extracted from human cells and with codons coding for cystatin C or a modified cystatin C is introduced.
Patent AU-1951692-A (AU)
Title: Mechanical face seals
IPC: F16J15/36
Filed: 1992-07-07
Abstract: A mechanical face seal has a first seal face member (10) mounted in fixed rotational and axial relationship and sealed with respect to a housing (13), and a second seal face member (21) mounted with respect to a shaft (20) by means of an elastomeric bellows unit (25), the bellows unit (25) being axially compressed so that it urges the second seal face member (21) into sealing engagement with the first seal face member (10); the elastomeric bellows unit (25) being formed from an elastomeric composition with reinforcing fibres embedded therein, the reinforcing fibres being orientated axially of the bellows unit (25). <IMAGE>
Patent AU-1964488-A (AU)
Title: Device for presenting objects
Inventor: PECH RUDIGER
IPC: G09F5/00
Filed: 1988-06-27
Abstract: PCT No. PCT/DE88/00381 Sec. 371 Date Apr. 24, 1989 Sec. 102(e) Date Apr. 24, 1989 PCT Filed Jun. 27, 1988 PCT Pub. No. WO88/10485 PCT Pub. Date Dec. 29, 1988.A device for the visual presentation of visually combinable objects which are reproduced on two separate boards which are capable of guided movement relative to each other. One board has an image of a main object with an aperture at a desired location, such that a second object shown on the second board may be viewed through the aperture. For example, the main board may contain a picture of an automobile with apertures where the wheel hubs are located. The second board may contain an assortment of wheel hubs. By manipulating the guide in various directions, different wheel hubs can selectively be made to appear in the aperture on the main board, thereby showing the automobile with different wheel hubs for comparison purposes.
Patent AU-2407195-A (AU)
Title: Dust filter bag for a vacuum cleaner
Inventor: LIENENLUKE PAUL
IPC: A47L9/14
Filed: 1995-04-22
Abstract: PCT No. PCT/EP95/01528 Sec. 371 Date Jan. 21, 1997 Sec. 102(e) Date Jan. 21, 1997 PCT Filed Apr. 22, 1995 PCT Pub. No. WO95/29621 PCT Pub. Date Nov. 9, 1995A dust filter bag (1) for a vacuum cleaner (3), with a retaining plate (H). The bag is constructed of a solid paper material, such as cardboard for example, to which a dust bag (12) is joined, for example adhesively, with a closure flap (13) turned towards the inside (15) of the dust bag (12), hinged on the retaining plate (H), which closure flap (13) is openable against a spring action and, in closed condition, keeps closed an opening (O) in the retaining plate (H). To make the dust filter bag simpler in construction and more advantageous as regards use, a band-like spring element (F) is attached to the closure flap (13) in such a way that, in the closed condition (FIG. 4), there is formed a clearance (Y) between a band end (E-E) and a hinge axis (14), lying outside of the band, of the closure flap (13), where the hinge axis (14) is provided turned towards the inside (15) of the dust bag (1).
Patent AU-2512388-A (AU)
Title: Hard-surface cleaning composition containing iminodiacetic acid derivatives
IPC: C11D3/43
Filed: 1988-11-14
Abstract: Hard-surface cleaning compositions are disclosed, containing an organic solvent having a boiling point above 90 DEG C, and a chelating agent derived from iminodiacetic acid.
Patent AU-2524600-A (AU)
Title: Novel pyrazolone compound and ophthalmic plastic lens using the same
Inventor: IWAMOTO HIDETOSHI
IPC: A61L27/16
Filed: 2000-04-04
Abstract: Provided are novel pyrazolone compounds which have excellent copolymerizability and undergo no elution in an organic solvent when used for an ophthalmic plastic lens and which have an excellent absorption peak in visible light region and function as a reactive yellow dye. <IMAGE>   <IMAGE>   <IMAGE>   <IMAGE>   <IMAGE>
Patent AU-2526795-A (AU)
Title: Il-6 activity inhibitor
Inventor: PEZZOTTI ANNARITA
IPC: C07K14/47
Filed: 1995-05-11
Abstract: PCT No. PCT/EP95/01778 Sec. 371 Date Nov. 10, 1997 Sec. 102(e) Date Nov. 10, 1997 PCT Filed May 11, 1995 PCT Pub. No. WO96/35782 PCT Pub. Date Nov. 14, 1996The invention relates to a nucleotide sequence, which is able to inhibit the IL-6 activity, its use in therapy as well as pharmaceutical compositions containing it. In particular, it relates to a nucleotide sequence which comprises: i) at least one nucleotide sequence that is an APRE element of general formula ZXMYKGKAA, wherein Z represents T or G or can also be absent, X represents T or can also be absent, M represents C or A, Y represents C or T and K represents T or G, in conjunction with ii) at least one nucleotide sequence constituting a transcription factor binding site other than the APRE element, such as those present in promoter regions.