baber/WOPTO huggingface dataset:
Patent EP-4159192-A1 (EP)
Inventor: ANTALICH ALEJANDRO
IPC: A61P25/00
Filed: 2021-12-30
Abstract: The present invention relates to a multidose nasal spray with mucoadhesive properties that gels in situ containing the psychedelic tryptamines DMT or 5-MeO-DMT or pharmaceutically acceptable salts or derivatives thereof, which can be used for personalized treatment of neurological and psychiatric disorders.
Patent EP-4166150-A1 (EP)
Inventor: RUFFIE PAULINE
IPC: C07K16/18
Filed: 2021-10-15
Abstract: The present invention relates to an association of a  Faecalibacterium prausnitzii  bacterial strain deposited to the CNCM under the accession number 1-4573; and at least one immune checkpoint inhibitor, in particular at least one monoclonal antibody selected from the group consisting of anti-PD-1, anti-PD-Ll and anti-CTLA-4 monoclonal antibodies for its use for preventing and/or treating a cancer in a mammal patient. The association as such is also considered.
Patent EP-4094191-A1 (EP)
Title: Uwb-token
Inventor: DRESSEL OLAF
IPC: G06K19/07
Filed: 2021-01-19
Abstract: Die Erfindung betrifft ein UWB-Token (112), welches eine UWB-Antenne (134) zum Senden und Empfangen von UWB-Signalen umfasst. Die UWB-Antenne (134) umfasst eine Mehrzahl von leitfähigen Antennenstrukturen (142). Die Antennenstrukturen (142) weist eine geometrische Kodierung mit einem das UWB-Token (112) identifizierenden individuellen Resonanzmuster auf.
Patent EP-4100525-A1 (EP)
Inventor: MULLIGAN PETER
IPC: A61K39/00
Filed: 2021-02-04
Abstract: The present invention relates to a method for preventing or treating a cancer disease by targeting the epigenetic factor Chromodomain on Y-like 2 (CDYL2). The inventors found that CDYL2 is commonly over-expressed in cancer and high CDYL2 levels correlate with poor prognosis in a number of cancer types even in drug resistant cancer. CDYL2 upregulation in a breast cancer cell line induced migration, invasion, stem-like phenotypes, as well as an epithelial-to- mesenchymal transition (EMT). Due to the importance of EMT and stemness in therapeutic resistance and relapse in cancer, the inventors propose that CDYL2 inhibition will also be beneficial to the treatment of such cancers. Furthermore RNAi inhibition of CDYL2 diminished these same EMT-associated processes in the mesenchymal-like breast cancer cell line. Finally ablating the expression of CDYL2 with RNAi 1) stimulates the expression of genes associated with an anti-tumor immune response (such as gene involved in interferon response) and 2) inhibits lung tumorigenesis in a preclinical model (mouse injected with the triple negative MDA-MB-231 cell line). These results show that CDYL2 as a strong candidate proto-oncogene and therapeutic target in cancer and also contributes to the anti-tumoral immune response escape.
Patent EP-4042480-A1 (EP)
Inventor: HÄNSEL STEFAN
IPC: H01L23/64
Filed: 2021-01-25
Abstract: L'invention concerne un commutateur, en particulier destiné à être utilisé en tant que commutateur à courant continu, composé d'un commutateur à semi-conducteur qui peut être mis hors circuit et d'un circuit série, le circuit série étant disposé en parallèle avec le commutateur à semi-conducteur qui peut être mis hors circuit et comprenant une première résistance, un condensateur et une seconde résistance, les première et seconde résistances étant construites conjointement sous la forme d'une résistance bifilaire afin de former une boucle de commutation à inductance particulièrement faible.
Patent EP-4125491-A1 (EP)
Inventor: LAW MAN CHUNG
IPC: A45D2/36
Filed: 2021-03-30
Abstract: A hair styling device (1) comprises a hinge jaw assembly (10) including a first jaw (11) having a first plate (12) and a second jaw (13) having a second plate (14). In an opened position of the jaw assembly (10), hair can be received between the plates (12, 14), and in a closed position of the jaw assembly (10), hair can be hair styled between the plates (12, 14). The hair styling device (1) further comprises a heater arrangement (20) configured to heat at least one of the plates (12, 14), and a hair wetness control mechanism (30) configured to supply a mist of liquid between the plates (12, 14) in the closed position of the jaw assembly (10), wherein the hair wetness control mechanism (30) includes a two-fluid nozzle (31), and an air pump (33) and a liquid tank (35) connected to respective inlets of the two-fluid nozzle (31). Preferably, the hair wetness control mechanism (30) is arranged to suck liquid from the tank (35) as a result from a flow of air that is generated by the air pump (33), without a need for a separate pump to obtain a flow of the liquid in the two-fluid nozzle (31).
Patent EP-4127118-A1 (EP)
Title: Water-glycol hydraulic fluid composition and supplementary additive therefor
Inventor: KANEKO HIROSHI
IPC: C10M173/02
Filed: 2021-04-01
Abstract: The present invention provides a water-glycol hydraulic fluid composition comprising an alkanolamine compound according to the general formula (1), wherein the water-glycol hydraulic fluid composition comprises 20-60% by mass water, 20-60% by mass glycol, 0.6-1.2% by mass fatty acid lubricant, and 0.01-0.06% by mass alkaline hydroxide compound selected from potassium hydroxide and/or sodium hydroxide, and has an alkali reserve of 10-25, wherein R 1  and R 2  are hydrocarbon groups having from 1 to 8 carbon atoms, and R 3  is a hydrocarbon group having 2 or more carbon atoms.
Patent EP-4125727-A1 (EP)
Inventor: ANDERSON DANIEL COREY
IPC: A61F2/24
Filed: 2021-04-01
Abstract: Examples of the disclosure are directed toward a valve device comprising an opening and a leaflet and methods of operating and manufacturing the valve device. In some embodiments, the leaflet is a three-dimensional thin-film leaflet, and the leaflet comprises a dome portion. In a first configuration, the leaflet of the valve device may occlude the opening of the device. In a second configuration, the leaflet may not occlude the opening, and blood may flow across the opening of the device. The valve device may be collapsible for transportation in a catheter.
Patent EP-4143560-A1 (EP)
Inventor: REIDER FOREST
IPC: G01N33/18
Filed: 2021-04-27
Abstract: A method is disclosed for determining antifreeze content in a fluid of an HVAC system, the method comprising receiving (S2) measurement data of the fluid, the measurement data comprising a measured temperature of the fluid and a measured speed of sound in the fluid; calculating (S4), for each of a plurality of antifreeze concentration values a fitting parameter, using the measurement data and at least one of: previous measurement data or previous antifreeze concentration data; and determining (S6) an antifreeze concentration in the fluid by selecting the antifreeze concentration value with an optimal fitting parameter.
Patent EP-4147526-A1 (EP)
Title: Repetition indication for random access procedure
Inventor: LY HUNG DINH
IPC: H04W72/04
Filed: 2021-05-06
Abstract: A method for wireless communication by a user equipment (UE) includes transmitting, to a base station, a random access preamble to initiate a random access procedure. The method also includes receiving, from the base station based on transmitting the random access preamble, a downlink message comprising a repetition number indicator. The method further includes transmitting a number of repetitions of a physical uplink channel based on the repetition number indicator.
Patent EP-4161340-A1 (EP)
Inventor: SCIUTTO ALBERTO
IPC: A47L15/44
Filed: 2021-06-04
Abstract: A washing agent dispenser for washing machines has a dispenser body that comprises a fixed dispenser part (200), designed for mounting on a wall delimiting a washing machine wash-chamber (3), and a removable dispenser part (100), couplable in a removable way to the fixed dispenser part (200). The removable dispenser part comprises a hollow body defining at least one tank for a substance in liquid or semi solid form, at least one first wall of the hollow body being intended to face at least partially at least one second wall of the fixed dispenser part (200). The dispenser (10) also comprises at least one sensor device (270), configured to provide at least one electrical signal representative of at least one of a level and a qualitative characteristic of the substance contained within the at least one tank. The at least one sensor device (270) is arranged at least partly on the fixed dispenser part (200).
Patent EP-4168752-A1 (EP)
Inventor: KIRST MICHAEL
IPC: G01F25/00
Filed: 2021-06-15
Abstract: Das Meßsystem umfaßt einen Meßwandler (10) vom Vibrationstyp sowie eine mit dem Meßwandler (10) elektrisch gekoppelte Meßsystem-Elektronik (20) zum Ansteuern des Meßwandlers und zum Auswerten von vom Meßwandler gelieferten Schwingungsmeßsignalen (s1, s2). Die Erregeranordnung weist einen Schwingungserreger (31) auf, der eingerichtet ist, elektrische Leistung mit einem zeitlich veränderlichen elektrischen Strom in mechanische Leistung zu wandeln, derart, daß an einem mittels des Schwingungserregers am damit mechanisch verbundenen Rohr gebildeten Antriebspunkt eine zeitlich veränderliche Antriebskraft auf das Rohr wirkt, wobei der Schwingungserreger (31) so positioniert und ausgerichtet ist, daß ein Antriebsversatz (ΔE), nämlich ein kleinster Abstand zwischen einer von einer durch den Antriebspunkt hindurchführende gedachte Umfangslinie des Rohrs umschlossenen Antriebs-Querschnittsfläche des Rohrs und einer vorgegebenen Referenz-Querschnittsfläche des Rohrs nicht mehr als 3°mm und/oder weniger als 0,5% der Rohrlänge beträgt, und wobei ein zwischen zwei Schwingungsbäuchen von Schwingungsbewegungen des wenigstens einen Rohrs in einer (von einer Schwingungsmode erster Ordnung abweichenden) Schwingungsmode zweiter oder höherer Ordnung gebildeter Schwingungsknoten nämlicher Schwingungsbewegungen innerhalb der Referenz-Querschnittsfläche liegt. Die Meßsystem-Elektronik (20) ist eingerichtet, mittels eines einen zeitlich veränderlichen elektrischen Strom aufweisenden elektrischen Treibersignals (e1) elektrische Leistung in den Schwingungserreger (31) einzuspeisen, derart, daß das Rohr erzwungene mechanische Schwingungen mit einer oder mehreren durch das Treibersignal (e1) vorgegebenen Schwingungsfrequenzen ausführt, wobei die Meßsystem-Elektronik sowohl das Treibersignal (e1) mit eine (Wechselstrom-)Frequenz (f eN1 ) bzw. eine (Wechselstrom-)Frequenz (f eN2 ) aufweisenden sinusförmigen (Nutz-)Stromkomponenten (eN1, eN2) bereitstellt, derart, daß die (Wechselstrom-)Frequenz (f eN1 ) von einer Resonanzfrequenz (f 2n+1 ) einer dem Rohr naturgemäß innewohnenden Schwingungsmode von ungeradzahliger Ordnung und die (Wechselstrom-)Frequenz (f eN2 ) von einer Resonanzfrequenz (f2n+2) einer dem Rohr naturgemäß innewohnenden Schwingungsmode von geradzahliger Ordnung jeweils um weniger als 1% und/oder um weniger als 1 Hz abweicht, als auch anhand dementsprechender Nutz-Signalkomponenten (s1N1; s2N1; s1N2; s2N2) wenigstens eines der Schwingungsmeßsigale (s1, s2) für wenigstens einen Strömungsparameter eines im Meßwandler geführten Meßstoffs Meßwerte ermittelt.
Patent EP-4093955-A1 (EP)
Inventor: LUNDSTRÖM JOHAN
IPC: F01N11/00
Filed: 2021-01-12
Abstract: The present invention relates to a method for adaption of an exhaust treatment system arranged for treating an exhaust stream (42) produced by an engine (14), where the exhaust treatment system includes at least a first additive dosage device (44), a first selective catalytic reduction catalyst (48) arranged downstream of the first additive dosage device, a second additive dosage device (50) arranged downstream of the first selective catalytic reduction catalyst, and a second selective catalytic reduction catalyst (54) arranged downstream of the second additive dosage device. The method includes initiating an adaption of the second selective catalytic reduction catalyst (54), and controlling, during the adaption of the second selective catalytic reduction catalyst (54), the first additive dosage device (44) to inject additive in accordance with at least one injection rule being designed for the adaption.
Patent EP-4193669-A1 (EP)
Inventor: AWADA AHMAD
IPC: H04W36/00
Filed: 2021-07-23
Abstract: A method comprising, during multi-connectivity: sending a reconfiguration message for execution by a user equipment; and sending a flag indicating an action to be taken by the user equipment during or after execution by the user equipment of an existing reconfiguration message, wherein the flag is configured to distinguish between at least two of the following actions: discarding the reconfiguration message; executing the reconfiguration message after executing an existing reconfiguration message; or prioritizing execution of the reconfiguration message over execution of an existing reconfiguration message.
Patent EP-4074868-A1 (EP)
Inventor: SOTO HERNANDEZ MARC
IPC: C09K13/00
Filed: 2021-01-28
Abstract: Solid electrolyte for dry electropolishing of metals, that comprises: At least a type of active particles of resin of ionic exchange charged with an acid solution that generate a chemical activity and an electric activity, at least a type of moderating particles of the chemical action and/or moderating particles of the electric conductivity of the active particles, so that the moderating particles reduce the attacks localized on the surface of the polished part provoked by the exudates of the active particles.
Patent EP-4185621-A1 (EP)
Title: Procédé de préparation d'un polyéthylène multimodal
Inventor: KIPIANI GEORGY
IPC: C08F210/16
Filed: 2021-07-23
Abstract: L'invention concerne un procédé de préparation d'un polymère d'éthylène multimodal dans un procédé en plusieurs étapes en présence d'un catalyseur comprenant un complexe de formule (lx), chaque X étant un ligand donneur sigma ; chaque Het est indépendamment un groupe hétéroaromatique ou hétérocyclique monocyclique ou polycyclique contenant au moins un hétéroatome choisi parmi O, N ou S ; L est un pont divalent à base de carbone, de silicium ou de germanium dans lequel un ou deux atomes de squelette relient les ligands ; M représente Ti, Zr ou Hf ; chaque R1 est identique ou différent et est un groupe alkyle CMO linéaire, ou un groupe alcoxy CHO linéaire, chaque n étant de 0 à 3 ; chaque R2 est identique ou différent et est un groupe alkyle en C1-10, un groupe alcoxy en C1-10 ou un groupe -Si(R)3 ; chaque R est identique ou différent et est un groupe alkyle ou phényle en C1-10 facultativement substitué par 1 à 3 groupes alkyle en C1-6 ; et chaque p est de 0 à 3.
Patent EP-4204202-A1 (EP)
Inventor: KANNENGIESSER DAMIEN JEAN-PHILIPPE
IPC: B29B11/14
Filed: 2021-07-30
Abstract: A method for heating a preform (1) comprising a body portion (4) extending along a longitudinal axis (A1). The method comprises the following steps: - introducing the preform (1) into a heating apparatus (5) comprising an array of infrared emitters (50) arranged in multiple columns (Cj) and rows (Ri); - setting power levels of the infrared emitters (50) so as to divide said array into subsets of columns (SCn); and - heating the preform while translating it in a direction parallel to the rows (Ri), and simultaneously rotating it around its longitudinal axis, the rotation and translation speeds, and the power levels of the infrared emitters (50) being set so that the power levels of the subsets of columns (SCn) facing zones (42) of the body portion extending longitudinally are different from the power levels of the subsets of columns facing the rest of the body portion, said zones extending relative to one another in a polygonal array.
Patent EP-4192273-A1 (EP)
Inventor: ADAIR KYLE
IPC: A61M11/04
Filed: 2021-08-09
Abstract: An aerosol generating device (10) for delivering aerosol upon heating a liquid comprises an elongate outer casing (12) with a cavity (14) for receiving a cartomizer (16) at a first end (22), an autonomous power supply device (18), and an electronic circuitry control board (20). The device (10) has a second end (24) longitudinally opposite to the first end (22), such that the autonomous power supply device (18) is positioned between the electronic circuitry control board (20) and the receiving cavity (14), and the electronic circuitry control board (20) is positioned between the second end (24) and the power supply device (18) with its main surface parallel to a longitudinal axis of the device (10). The power supply device (18) is distant from the second end (24) of the device (10) at least a length (LI) representing between a quarter and a third of the total length (L) of the device (10), in particular at least a length (LI) of 15 mm.
Patent EP-3953330-A1 (EP)
IPC: A61P31/14
Filed: 2021-08-06
Abstract: The invention relates to compounds of Formula (I'') wherein R, R1, R2, R3, p, q and q' are as defined herein, pharmaceutical compositions comprising the compounds, methods of treating coronavirus infection such as COVID-19 in a patient by administering therapeutically effective amounts of the compounds, and methods of inhibiting or preventing replication of coronaviruses such as SARS- CoV-2 with the compounds.
Patent EP-4111791-A1 (EP)
Inventor: ZHOU YAN
IPC: H04W72/04
Filed: 2021-02-23
Abstract: Wireless communications systems and methods related to beam failure detection (BFD) in a dormancy bandwidth part (BWP) are provided. A user equipment (UE) determines to operate in a dormancy mode for a cell of a wireless communication network. The UE operates in the dormancy mode for the cell of the wireless communication network, where the operating in the dormancy mode includes performing a beam failure detection (BFD) in a dormancy bandwidth part (BWP) based on a configuration. The configuration may include a control resource set (CORESET) configuration for the dormancy BWP.
Patent EP-4196899-A1 (EP)
Title: Techniques for persisting data across instances of a cloud shell
Inventor: KASSO CHRISTOPHER S
IPC: G06F11/14
Filed: 2021-08-12
Abstract: Techniques for persisting user data across secure shell instances are provided. The techniques include a method wherein a computer system receives a request to reserve a block volume, the request being received from a session manager service. The method also includes reserving the block volume, identifying a data center identifier of the block volume, returning the data center identifier of the block volume to the session manager service, attaching the block volume to a volume management fleet machine, receiving an instruction from the session manager service to release the block volume, creating a backup of the block volume comprising the data stored in the block volume, and releasing the block volume.
Patent EP-4204264-A1 (EP)
Inventor: ROBERTS WILL E
IPC: B60T17/00
Filed: 2021-08-18
Abstract: A sealing assembly for installation on a port of a spring brake actuator includes a plug, a one-way valve and a cap. The plug receives the one-way valve for providing one-way air flow through the orifices and maintaining about two psi in the spring brake chamber at zero stroke. An elastomeric piece is affixed to a first set of segments of the plug for sealing against an inner surface of the port. The cap has arms sized to extend around a third set of segments of the plug and snap onto the plug. A fourth set of segments of the plug elastically deform so the sealing assembly can be installed and removed from the port easily.
Patent EP-4199870-A1 (EP)
Inventor: VOORHEES ANDREW
IPC: A61F9/008
Filed: 2021-08-18
Abstract: In laser-assisted corneal lenticule extraction procedures, the lenticule incision profile includes anterior and posterior lenticule incisions, with one or more of the following features: plano transition zone outside the optical zone, to improve mating of anterior and posterior incision surfaces after lenticule extraction; shallow arcuate incisions above the anterior incision and near the lenticule edge, to improve surface mating; separate ring cut intersecting the anterior and posterior incisions in the transition zone, to reduce tissue bridges and minimize tear at the lenticule edges and facilitate easy lenticule extraction; larger posterior incision, which includes a pocket zone outside the lenticule edge, for better surface mating and bubble management during cutting; and a separate ring shaped pocket cut intersecting the pocket zone of the posterior incision, for bubble management. An entry cut can intersect either the pocket zone of the posterior incision or an entry extension zone of the anterior incision.
Patent EP-4121044-A1 (EP)
Title: Androgen receptor regulation by small molecule enantiomers
Inventor: AGUS DAVID B
IPC: A61K31/40
Filed: 2021-03-22
Abstract: Herein is reported a class of chiral compounds with paradoxical effects on the androgen receptor (AR). The ( R )-enantiomers behave like classical anti-androgens while the ( S )-enantiomers activate AR signaling. In castration-resistant prostate cancer, the change during the course of therapy to growth in the presence of AR targeted therapeutics, a harbinger of progression to lethal disease, is commonly attributed to acquired mutations of the AR-ligand binding domain. This is the first report of an antagonist -agonist duality solely due to structural enantiomerism, without any modification to the AR binding site.
Patent EP-3992972-A1 (EP)
Inventor: CHEN YUI-LANG
IPC: G11C29/44
Filed: 2021-06-16
Abstract: The present disclosure relates to a method and device for determining a fail bit repair solution, and a chip, relates to the field of integrated circuit technology, and is applicable to a scene for repairing a fail bit in the chip. The method for determining a fail bit repair solution is as follows. A local region to be repaired including the fail bit is determined. A preliminary repair LR circuit for repairing the local region to be repaired is determined (S210). A region level of the local region to be repaired is determined (S230) according to the number of available GR circuits other than any replacement GR circuit configured for replacing the preliminary repair LR circuit and the number of available LR circuits. It is controlled, according to the region level of the local region to be repaired, to repair the fail bit by the GR circuit or the LR circuit (S240). With the present disclosure, chip process yield may be improved effectively, reducing the chance of a chip turning useless.
Patent EP-4129076-A1 (EP)
Inventor: YANAGISAWA MASANOBU
IPC: A23J3/00
Filed: 2021-03-26
Abstract: The purpose of the present invention is to provide a manufacturing method of a plant-based cheese-like food with enhanced umami similar to cheese made from animal ingredients. This plant-based cheese-like food manufacturing method is characterized by subjecting vegetable protein-containing raw ingredients to the action of nuclease and then acidifying.
Patent EP-4125618-A1 (EP)
Inventor: BASUDE RAGHUVEER
IPC: A61B17/04
Filed: 2021-03-25
Abstract: A clip for immobilizing leaflets of a cardiac or venous valve includes a hub having a pair of tangle resistant spring-biased outer arms coupled to an inferior end of the hub and a pair of tangle resistant spring-biased inner arms adjacent to the outer arms and coupled to a superior end of the hub. A delivery catheter with stiffening members configured to position the valve clip adjacent a target valve while the outer and inner arms are biased in an opened position relative to each other. The delivery catheter or clip comprises of sutures that assist in bail out. After the valve leaflets are located between the opened outer and inner arms, the biasing forces may be released to allow the clip to self-close the clip over the valve leaflets, to atraumatically and effectively cinch and coapt the leaflets.