baber/WOPTO huggingface dataset:
Patent CA-2377567-A1 (CA)
Title: High throughput assay system
Inventor: KRIS RICHARD M
IPC: C12Q1/68
Filed: 2000-06-21
Abstract: The present invention relates to compositions, apparatus and methods useful for concurrently performing multiple, high throughput, biological or chemica l assays, using repeated arrays of probes. A combination of the invention comprises a surface, which comprises a plurality of test regions, at least t wo of which, and in a preferred embodiment, at least twenty of which, are substantially identical, wherein each of the test regions comprises an array  of generic anchor molecules. The anchors are associated with bifunctional linker molecules, each containing a portion which is specific for at least o ne of the anchors and a portion which is a probe specific for a target of interest. The resulting array of probes is used to analyze the presence or test the activity of one or more target molecules which specifically interac t with the probes. In one embodiment of the invention, the test regions (which  can be wells) are further subdivided into smaller subregions (indentations, or dimples).
Patent CA-2377743-A1 (CA)
Title: Improvement to the exchange and release of an amine from its carbamoyl fluoride
Inventor: ROCHIN CHRISTOPHE
IPC: C07C209/62
Filed: 2000-07-04
Abstract: The invention concerns a method for treating an aryl carbamoyl fluoride, comprising in its molecule at least a perhalogenated aliphatic carbon, which bears at least a halogen atom to be exchanged with the fluorine. The method comprises a step which consists in contacting said carbamoyl fluoride with hydrofluoric acid, the hydrofluoric acid/carbamoyl fluoride ratio being maintained during the reaction at a value less than 4, preferably 5. The invention is characterised in that said ratio is not more than 11. The invention is applicable to organic synthesis.
Patent CA-2379158-A1 (CA)
Inventor: VANDER LOUW STEVEN J
IPC: C08L101/10
Filed: 2000-07-18
Abstract: The present invention provides curable compositions comprising the hydrosilation product of olefin-containing polymers and organosiloxane hydrides. The curable compositions may be cured to form low surface energy cured composition which may be suitable, for example, as antifouling coatings on substrates such as boat or ship hulls.
Patent CA-2379629-A1 (CA)
Title: Apparatus and method for re-shaping brake cores
Inventor: BOSTIC LAWRENCE E
IPC: B23P6/00
Filed: 2000-06-28
Abstract: A coining die apparatus (10) for reshaping the backing plates (72) of spent rotary drum brake cores (11) in the production of remanufactured brake shoes comprises a lower die (30) having a concave working surface (35) configured to support a convex outer surface (12) of a brake core backing plate (72) to be coined. A  moveable upper die (55, 74, 58) includes axially-spaced outer die portions (55, 58) and a middle die portion (74) between the outer portions (55, 58) having convex working surfaces (66). The middle (74) and outer die portions (55, 58) are spaced laterally to accommodate a pair of mounting brackets (14) extending from a convex inner surface of the backing plate (72). The middle die portion (74) enters between the brackets (14) when the dies (30, 55, 74, 58) are closed to strike and reshape a corresponding middle region (78) of the backing plate (72) between the brackets (14), while the outer die portions (55, 58) strike and reshape corresponding side portions (72, 70) of the mounting plate (16) adjacent either side of the mounting brackets (14).
Patent CA-2381310-A1 (CA)
Title: Stationary axle/wheel lock device
Inventor: HOWITT DOUGLAS R
IPC: B60R25/09
Filed: 2002-04-16
Abstract: A stationary axle / wheel lock anti-theft device for positioning and encumbering vehicle axle / wheel assembly movement in X - Y - Z - axis planes. Said device includes a base, a cylindrical blocking member and a security lock assembly. A frontal wheel barrier integral to the base restricts access to the front face of the vehicle wheel rim, axle hub, wheel nuts and cylindrical blocking member. Said barrier provides a restraining bore for the cylindrical blocking member in the locked position. Wheel chocks integral to the base localizes the vehicle wheel assembly, substantially aligning the vehicle axle with the cylindrical blocking member coaxially. The cylindrical blocking member is restrained in the extended position by mechanical means and serves to protect a security lock device from tampering. The cylindrical blocking member obstructs forward or rearward movement once the vehicle wheel assembly makes contact.
Patent CA-2381781-A1 (CA)
Title: End to side anastomotic implant
Inventor: MCCLELLAN SCOTT B
IPC: A61F2/06
Filed: 1999-09-13
Abstract: An anastomosis apparatus includes a first rigid element (10), and a second rigid element (20). The first element defines a first passageway or lumen which extends along its entire length. In construction the first element includes a first tubular portion in association with a first flange (12) disposed on one end of the first tubular portion. The first flange (12) is fixedly secured to the first tubular portion (11). The second element defines a second passageway along its entire length which is dimensioned to sliding receive, and retain the first tubular portion. The second element (20) includes a second tubular portion (21) in association with a second flange (22) disposed on a proximal end of the second tubular portion. An engagement of the first element with the second element about an opening defined in the blood vessel of a patient results in a fixed spatial relationship of the first element relative to the second element, whereby the first passageway is retained in a generally fixed spatial relationship with the lumen of the aforesaid blood vessel.
Patent CA-2383336-A1 (CA)
Title: Thumb for scooping tool arm
Inventor: FRIGON DENIS
IPC: E02F3/40
Filed: 2002-05-16
Abstract: The thumb is used on a hydraulic tool arm equipped with a scooping tool f or selective co-operation between the scooping tool and the thumb. The thumb ha s a pair of generally parallel U-shaped lateral forks defining an opening therebetween f or engagement of the tool arm between the forks. The forks define an inner end having a transverse coupling member for operative coupling of the thumb to the tool arm for movement of t he thumb about the tool arm, and an outer free end opposite the inner end. The forks are significantly curved about a common axis.
Patent CA-2383648-A1 (CA)
Title: Flame-resistant polycarbonate abs blends
Inventor: ZOBEL MICHAEL
IPC: C08K5/5353
Filed: 2000-08-22
Abstract: The invention relates to polycarbonate ABS moulding materials which are provided with phosphanatamine and which have an excellent flame resistance a nd very good processing properties such as improved flow behaviour, an improved  elastic modulus and reduced deposit build-up on tools. The graft polymer is produced using mass, mass-solution or mass-suspension polymerisation methods .
Patent CA-2383713-A1 (CA)
Title: Managing attribute-tagged index entries
Inventor: HURAS MATTHEW A
IPC: G06F16/901
Filed: 2002-04-26
Abstract: The invention herein provides method and apparatus for managing attribute- tagged index entries contained in an index by assigning or tagging an index entry attribu te indicator to a newly inserted index entry (that is, at the time when a key data value is inserted into the index, the key data value becomes a newly inserted index entry and an attribute indicator i s tagged to the newly inserted index entry). The index entry can be placed anywhere within the index. Once a group of attribute-tagged index entries have been inserted into the index, the attribute identifiers can be switched off instantaneously (that is, the attribute associated with the attribute indicators is disabled). For example, an attribute identifier can be used to defer accessibility of appropriately attribute-tagged index entries until a predetermined time later when the attribute can be disabled and thus allow users to access the attribute-tagged index entries without having to remove the attribute indicators from the index).
Patent CA-2384037-A1 (CA)
Title: Pyrazolo[4,3-d]pyrimidines
Inventor: SCHELLING PIERRE
IPC: A61P15/10
Filed: 2000-08-24
Abstract: Pyrazolo[4,3-d]pyrimidines of the formula I  (see formula I) and their physiologically acceptable salts, in which R1, R2, R3, R4 and X have the meanings indicated in Claim 1, exhibit phosphodiesterase V inhibition and can be employed for the treatment of disorders of the cardiovascular system and for the treatment and/or therapy of potency disorders.
Patent CA-2385914-A1 (CA)
Title: Synchronization method and apparatus
Inventor: RASANEN JUHA
IPC: H04W56/00
Filed: 1999-10-11
Abstract: The present invention relates to a synchronization method and apparatus, wherein a first end point entering a connection mode change state transmits a request message to a second end point. The second endpoint enters the connection mode change state in response to the receipt of the request message and transmits an acknowledgment and a numbered frame to the first end point. Having received the acknowledgment, the first endpoint leaves the connection mode change state and transmits an aknowledgment acknowledging the numbered frame to the second end point which leaves the connection mode change state in response to the receipt of the acknowledgment. Thus, the receipt of the acknowledgment acknowledging the numbered frame is received by the second end point irrespective of a DTX condition at the first end point, since a numbered frame is always acknowledged.
Patent CA-2386903-A1 (CA)
Title: Communications apparatus
Inventor: TSUMURA MIHOJI
IPC: H04L47/76
Filed: 1994-07-11
Abstract: The invention prevents unauthorized use of data in communications. When terminals with different data transmission rates are simultaneously connected to a host computer, the host computer sets a single common data communication rate to all the terminals to assure synchronization. The host computer is connected each terminal via communications network. The host computer sends a data body to each terminal over a unilateral communications link in a cyclic manner while a bilateral communications link is established between the host computer and each terminal.      Response to an individual request from each terminal, the host computer downloads descrambling data for descrambling and a loader for executing the data body. The host computer determines from among the terminals, any terminal having a communications means that sets the lowest data transmission rate, and sets the data transmission rates of the terminals simultaneously connected thereto to the lowest rate.
Patent CA-2387175-A1 (CA)
Title: Medical needle assemblies
Inventor: CAIZZA RICHARD JAMES
IPC: A61M5/34
Filed: 2002-05-21
Abstract: A medical needle device which is reusable and cooperates with a disposable needle assembly. The medical needle device includes a holder, a needle assembly, and an ejector rod cooperating with the holder. The needle assembly includes a needle hub and needle. The holder has a proximal end and a distal end and defines an opening extending therethrough. The distal end has a hub socket for receiving the hub of the needle, with the needle hub received in the socket.  The ejector extends into the opening from the proximal end of the holder. The ejector rod is slidably received in the holder and has a distal end configured to engage the needle hub, and a proximal end extending outward from the holder. The ejector rod is used to eject the needle assembly from the holder.
Patent CA-2387179-A1 (CA)
Title: Advertising system
Inventor: LEB DAVID E
IPC: G09F21/02
Filed: 2002-05-22
Abstract: An advertising method utilizes a person's or animal's body, such as the skin of the person's upper back and shoulder region, which is ideally exposed, broad and planar. The advertisement may be displayed during a sporting/entertainment event which is broadcast to a large audience through visual media such as television. In one embodiment, the event is a boxing match and the advertisement affixed on the boxer's back promotes an on-line wagering service. The advertised service can be employed or accessed during the boxing match or immediately after the advertisement is seen by the consumer. The advertisement is sufficiently large to be legible and comprehensible by the viewing audience. The advertisement may be formed of a suitable dye, ink or paint that can be removed after the match, but which is resistant to smudging from physical contact and/or perspiration.
Patent CA-2387438-A1 (CA)
Title: Protective footwear against landmine
Inventor: KRSTIC ALEXANDER
IPC: A43B7/20
Filed: 2000-09-07
Abstract: Footwear (1) to protect a wearer from landmines including a substantialy non - deformable metal sheet (5) below the foot of the wearer shaped and positione d to effect a redirection of any up-welling result of an exploding landmine to  a side of the footwear (1) when being worn. The footwear (1) also including an  outer hard shell (2) to deflect and direct any initial shock and pressure waves past the body elements of the wearer, the footwear (1) being pivotally  connected to an upper protective surround (13).
Patent CA-2389925-A1 (CA)
Title: Flame-resistant polycarbonate abs moulding materials
Inventor: WITTMANN DIETER
IPC: C08K5/5353
Filed: 2000-08-22
Abstract: The invention relates to polycarbonate moulding materials that are provided with phosphonatamines and phosphorus compounds. Said polycarbonate moulding materials have excellent flame resistance and very good mechanical properties such as weld line strength or elastic modulus and a good raw clay.
Patent CA-2390301-A1 (CA)
Title: Formulation d'inhibiteur de la hmg-coa reductase a liberation lente
Inventor: CHEN CHIH-MING
IPC: A61K9/36
Filed: 2000-11-03
Abstract: L'invention concerne une forme posologique solide à libération lente administrée par voie orale destinée à diminuer les taux de cholestérol sérique chez un être humain. Cette forme posologique contient un médicament comprenant un ester d'alkyle de naphtalènes hydroxy substituées (par exemple, la lovastatine) et un véhicule à libération lente, de sorte que cette forme posologique requiert un temps moyen pour la concentration plasmatique maximale (T¿max?) du médicament qui a lieu entre environ 10 et environ 32 heures après l'administration orale à des patients humains à raison d'une prise une fois par jour. Cette forme posologique produit une diminution des taux de cholestérol sérique efficace du point de vue thérapeutique. L'invention concerne également des méthodes permettant de diminuer les taux de cholestérol sérique chez les êtres humains.
Patent CA-2396006-A1 (CA)
Title: Automated system and method for monitoring financial transactions
Inventor: O'MARA TIMOTHY L
IPC: G06Q20/10
Filed: 2000-12-27
Abstract: An automated system and method which monitors the cash flow of a merchant account and maintains a minimum balance for each merchant account based upon allowable delays. See Figure 1. The system includes a transaction processor (10) in communication with the merchant credit card processor (12), a merchant database and a plurality of credit card issuers (28, 30, 32, 34). The transaction processor facilitates the flow of credit card transaction data by withholding a fraction of the net transactional amount based on transactional parameters to maintain a minimum merchant account balance.
Patent CA-2398207-A1 (CA)
Inventor: MATECZUN ALFRED J
IPC: A61K39/07
Filed: 2000-12-21
Abstract: On décrit des procédés permettant d'induire une réponse immunitaire qui protège un animal susceptible d'être atteint d'une infection létale par le (<i>Bacillus anthracis </i> (<i>B. anthracis</i>). Un procédé consiste à administrer au sujet une quantité efficace d'un facteur létal (FL) de <i>B. anthracis</i> de type sauvage ou de préférence d'une forme mutée de ce facteur létal ou encore un fragment immunogène de ce dernier. Un deuxième procédé consiste à administrer au sujet une quantité efficace d'une protéine FL mutée ou d'un fragment immunogène d'une protéine FL et une quantité efficace de l'antigène protecteur (AP) <i>B anthracis</i> ou un fragment immunogène de la protéine AP. Un troisième procédé consiste à administrer au sujet un polynucléotide ou un acide nucléique comprenant une séquence codant une protéine FL mutée <i>B. anthracis</i> ou un fragment immunogène d'une protéine FL. Un quatrième procédé consiste à administrer au sujet un polynucléotide qui comprend une séquence de codage pour une protéine FL mutée ou un fragment immunogène d'une protéine FL et un polynucléotide qui comprend une séquence de codage pour la protéine AP <i>B. anthracis</i> ou un fragment immunogène de cette dernière. La présente invention concerne également une composition immunogène à base de protéine ou de peptide utilisée pour préparer un vaccin lequel est capable de protéger prophylactiquement un sujet contre les effets létaux de l'infection par <i>B. anthracis</i> ou contre l'exposition à un agent toxique qui est produit par <i>B. anthracis</i>. La composition immunogène à base de protéine ou de peptide comprend une protéine FL purifiée ou de recombinaison ou un fragment immunogène de cette dernière et une protéine AP purifiée ou de recombinaison ou un fragment immunogène de cette dernière. La présente invention concerne également une composition immunogène à base d'acide nucléique comprenant un acide nucléique qui comporte une séquence codant la protéine FL ou un fragment immunogène de cette dernière et un polynucléotide qui comprend une séquence codant la protéine AP ou un fragment immunogène de cette dernière.
Patent CA-2398601-A1 (CA)
Title: Method and circuit for providing interface signals between integrated circuits
Inventor: SANI MEHDI HAMIDI
IPC: H03K19/0175
Filed: 2000-10-17
Abstract: Circuitry that generates an interface signal between a first and a second integrated circuit (IC). The circuitry includes a reference circuit that provides a reference signal, an interface circuit, and a circuit element. The interface circuit is implemented on the first IC, operatively couples to the reference circuit, receives the reference signal and a data input, and generates the interface signal. The circuit element is implemented on the second IC, operatively couples to the control circuit, receives the interface signal, and provides an output signal. The reference signal can be a voltage or a current signal, and can be generated in the first or second IC. The interface circuit can be implemented with a current mirror coupled to a switch array, and can be oversampled to ease the filtering requirement. The interface signal can be a differential current signal having multiple (e.g., four, eight, or more) bits of resolution. The circuit element can be, for example, a VGA, a modulator, or other circuits.
Patent CA-2399326-A1 (CA)
Title: Cryogenic crystallisation of fats
Inventor: BROOKER BRIAN EDWARD
IPC: A23D7/05
Filed: 2002-08-21
Abstract: A method of processing the solid fat phase of a food product which comprises or contains a dispersion of solid fat in an oil phase, the method comprising bringing the solid fat phase with a minimal amount of the oil phase in a liquid state to a cooling device and there cooling the product to effect fat crystallisation as quickly as possible.
Patent CA-2400328-A1 (CA)
Title: Procedes d'identification d'agents provoquant un phenotype letal, et de tels agents
Inventor: CAPONIGRO GIORDANO MICHAEL
IPC: C07K7/08
Filed: 2001-02-14
Abstract: L'invention concerne des procédés d'exécution de dosages de sélection négative permettant d'identifier des agents cytostatiques ou cytotoxiques provoquant un phénotype létal. Cette invention est également utile dans l'évaluation d'une éventuelle cytotoxicité et d'une cytotoxicité spécifique de cellules.
Patent CA-2400362-A1 (CA)
Inventor: PU CHUNMIN
IPC: C01B11/02
Filed: 2001-03-14
Abstract: Chlorine dioxide generating processes of the single vessel type which produc e chlorine dioxide of high purity are monitored and controlled by a computer using Advanced Control Strategies for steady, stable operation with optimum chemical usage on the basis of a desired chlorine dioxide production rate as  the sole input from an operator to the computer program effecting the comput er control.
Patent CA-2402611-A1 (CA)
Title: Bactericidal preparation
Inventor: BOECK HARRY
IPC: A61K31/04
Filed: 2001-03-14
Abstract: A bactericidal preparation in the form of a solution, cream or ointment is disclosed. The preparation comprises a liquid compounded from photosynthesized hydrocarbons, isolates from hydrocarbons, 2-hydroxy-1-isopropyl-4-methyl-benzene (thymol) and butylated hydroxytoluene.
Patent CA-2406488-A1 (CA)
Title: Combination poppet and gate valve
Inventor: BARTLETT CHRISTOPHER D
IPC: F16K1/44
Filed: 2001-04-26
Abstract: The present invention is directed to a valve (10) for controlling the flow of fluid through a component which includes a flow conduit (12) extending therethrough. The valve comprises a first closure member (40) for controlling the flow of fluid through the conduit, a second closure member (42) for controlling the flow of fluid through the conduit, and a valve stem (30) which is connected to both the first and second closure members. The stem is responsive to an external force to move the first and second closure members from a closed position, in which the fluid is blocked from flowing through the conduit by both the first and second closure members, to an open position, in which the fluid is permitted to flow through the conduit past both the first and second closure members.
Patent CA-2408904-A1 (CA)
Inventor: AYYAVOO VELPANDI
IPC: C12N15/861
Filed: 2001-03-29
Abstract: L'invention concerne des procédés permettant d'administrer un polypeptide à un patient. Les procédés mis en oeuvre selon l'invention consistent à administrer au patient un vecteur immunogène comprenant un acide nucléique codant pour le polypeptide désiré, en liaison coopérante avec des éléments régulateurs en combinaison avec une ou plusieurs des protéines Vpr, un fragment fonctionnel de protéine Vpr, un acide nucléique codant pour une protéine Vpr en liaison coopérante avec des éléments régulateurs, ou encore, un acide nucléique codant pour un fragment de protéine Vpr en liaison coopérante avec des éléments régulateurs. L'invention concerne également des méthodes d'inhibition d'une réponse immunitaire indésirable chez un patient, ainsi que des méthodes d'inhibition d'une prolifération cellulaire d'une cellule tumorale chez un patient.
Patent CA-2409294-A1 (CA)
Title: Ipsec processing
Inventor: TURTIAINEN ESA
IPC: H04L29/06
Filed: 2001-05-03
Abstract: A network device for implementing IPSec and comprising at least one IP  forwarder (IPFW) arranged to receive IP packets each of which is associated with a Security Association (SA). The IP forwarder(s) determines the destinations of the packets, and forwards the packets to their destinations. A  plurality of security procedure modules (SecProcs) are coupled to the IP  forwarder(s) and are arranged to implement security procedures for received IP  packets in parallel. A security controller (SC) is arranged to allocate negotiated SAs amongst the security procedure modules and to notify the security procedure modules and the IP forwarder(s) of the allocation, whereby the IP forwarder(s) can send IP packets to the security procedure module implementing the associated SA.
Patent CA-2411293-A1 (CA)
Title: Novel azalides and methods of making same
Inventor: DIRLAM JOHN PHILLIP
IPC: A61P31/04
Filed: 1999-12-15
Abstract: This invention relates to methods of preparing compounds of Formula 1:      and to pharmaceutically acceptable salts and solvates thereof, and to methods for preparing same.   The compounds of Formula 1 are antibacterial agents that may be used to treat various bacterial and protozoal infections, and may also be used to treat cancer. The invention also relates to pharmaceutical compositions comprising the compounds of Formula 1, and to methods of treating bacterial and protozoal infections by administering compounds of Formula 1.