baber/WOPTO huggingface dataset:
Patent CZ-1096-A3 (CZ)
Title: Imides functioning as inhibitors of tnp-alpha, process of their preparation, pharmaceutical composition based thereon and the use thereof
Inventor: MULLER GEORGE W
IPC: A61K31/165
Filed: 1994-07-01
Abstract: A process of preparing thalidomide in which N-phthaloylglutamine or N-phthaloylisoglutamine is cyclized with N,N'-carbonyldiimidazole, characterised in that the process comprises heating said N-phthaloylglutamine or N-phthaloylisoglutamine and N,N'-carbonyldiimidazole in refluxing anhydrous tetrahydrofuran.
Patent CZ-5193-A3 (CZ)
Title: Sewing machine needle and process for producing thereof
Inventor: TAKEI YOSHITSUGU
IPC: A61K9/08
Filed: 1993-01-20
Abstract: A sewing machine needle is manufactured by die-pressing the whole needle trunk portion without causing burrs on the needle trunk. A needle material (10) has its needle trunk (14, 16) drawn into two stages, and further, a thin portion (22) previously formed to form a scraped-out portion above a needle hole. By die-pressing, the opposite side portions of a needle groove (28) are extended to a predetermined angle, and the scraped-out portion (40) of a desirable shape and a needle hole portion (33) are formed. The needle thus obtained has sufficiently high rigidity as a whole and a space between the needle trunk and a sewing thread is large, so that sewing work can be stably carried out and operations at high speed can be performed. <IMAGE>
Patent CZ-6494-A3 (CZ)
Title: Feeding device, method of stepped feed of several carrier plates and method of putting articles in the carrier plate
Inventor: BERTA NORBERT I
IPC: A61J3/06
Filed: 1994-01-11
Abstract: Methods and apparatus for applying coating to products such as medicaments are disclosed. The present invention provides apparatus and methods for controlling the loading and feeding of tablets onto carrier plates (50) for transfer to various processing stations of the coating system. A novel plate indexing apparatus (300) includes a box cam follower device (314) mounted to an engagement bar (302) for incrementally advancing the plates in a precisely controlled manner. A second complementary shaped engagement bar (320) provides a locking mechanism to ensure the plates are always under positive control. In one embodiment the plate indexing apparatus also controls the feeding of the tablets. An alternative embodiment includes a vacuum pick-up system for feeding tablets onto the carrier plates as the plates are incrementally advanced.
Patent CZ-30594-A3 (CZ)
Title: Cyclic compounds of urea and pharmaceutical preparation in which they are comprised
Inventor: PELOSI STANFORD SALVATORE JR
IPC: A61K31/4155
Filed: 1992-08-10
Abstract: The novel cyclic ureas of the present invention are useful as antiarrhythmic and antifibrillatory agents and have general structure (I) <CHEM> wherein (a) X is a saturated or unsaturated, 5-, 6-, or 7-membered heterocycle or carbocycle; (b) R is selected from the group consisting of covalent bond, nil, heteroatom, carbonyl, heterocyclic ring, carbocyclic ring, alkyl, alkenyl, alkoxy, alkylamino, arylalkyl, aryloxy, acyl, acyloxy, and acylamino; (c) Y is a substituted or unsubstituted, saturated or unsaturated, 5-, 6-, or 7-membered heterocyclic ring or carbocyclic ring, or is nil; and wherein when R is nil, X and Y are fused ring systems; and when R is a covalent bond, X and Y are ring systems linked through a covalent bond; and when Y is nil, R is a covalent bond and X is bound to L through R; (d) R1, R2 and R3 are independently selected from the group consisting of nil, Cl, F, Br, NH2, CF3, OH, SO3H, CH3SO2NH, COOH, alkoxy, alkyl, alkoxycarbonyl, hydroxyalkyl, carboxyalkyl, aminoalkyl, acylamino, and acyloxy; (e) L is selected from the group consisting of alkylamino, alkenylamino, alkylimino, alkenylimino, and acylamino wherein the nitrogen atom thereof is bound to the nitrogen atom at the 1-position of the cyclic urea moiety; (f) R4 is selected from the group consisting of alkyl, alkenyl, alkynyl, alkylacyl, and heteroalkyl; (g) A is a substituted or unsubstituted, saturated or unsaturated, straight-chain or branched, C1-C8 heteroalkyl, or a substituted or unsubstituted, saturated or unsaturated heterocycle having 5-, 6-, or 7-members; and has one nitrogen atom, which is adjacent to R4; and (h) R5 is a substituted or unsubstituted C2 alkylene; and pharmaceutically-acceptable salts and esters thereof.
Patent CZ-9900639-A3 (CZ)
Title: Cardboard blank for independent reclosable package and method of making the package of the blank
Inventor: MELLON MARK
IPC: B65D83/04
Filed: 1999-02-25
Abstract: The invention relates to a paperboard blank 2 which is used for constructing a self-contained, reclosable package 60. In particular, blank 2 includes, in part, panels 4,6,8,10 and 12, fold lines 14,16,20,22,26,30,32,40,42,46 and 48, perforated areas 18 and 24, apertures 28 and 34, flaps 36 and 38, tab 44, and slot 50. After blank 2 is formed, articles 52 and 56 are placed on panels 6 and 8, respectively. Articles 52 and 56 are placed in conventional blister packs 54 and 58, respectively. Articles 52 and 56 can be different types of articles such as different types of medications. To form the self-contained, reclosable package, panels 12 and 10 are folded over, so that panel 12 overlays blister packs 54 and panel 6 and panel 10 overlay blister packs 58 and panel 8. After panels 10 and 12 are folded over, blister packs 54 and 58, respectively, are sandwiched between panels 12 and 6 and 10 and 8, respectively, in order to keep blister packs 54 and 58 in place. Panels 10 and 8, which now sandwich articles 56, are folded over panels 6 and 12. In this manner articles 56 are now adjacent to articles 52. Flaps 36 and 38 are folded over panel 8 such that panel 38 overlays panel 36 and tab 44 is inserted into slot 50. In this manner, articles 52 and 56 are retained in place and blank 2 can be reclosed after being opened by the end-user. Panel 4 is folded over flaps 36 and 38 to complete the construction of a self-contained, reclosable package 60 for retaining articles. <IMAGE>
Patent CZ-66996-A3 (CZ)
Title: Process of cutting ingots from hard materials to plates and a saw for making the same
Inventor: VOJTECHOVSKY KAREL RNDR
IPC: B26D1/46
Filed: 1996-03-06
Abstract: PCT No. PCT/IB97/00155 Sec. 371 Date Nov. 2, 1998 Sec. 102(e) Date Nov. 2, 1998 PCT Filed Feb. 25, 1997 PCT Pub. No. WO97/32681 PCT Pub. Date Sep. 12, 1997The invention concerns a method of cutting blocks of hard materials into plates by the action of an abrasive, which is added in the loose state, and of a continuous, revolving, fixed carrier. As a result of being guided in peripheral grooves in coaxial rollers of a roller system, the carrier forms a chain through which the material to be cut is pressed. The carrier, which runs in the peripheral grooves in the rollers of a roller system comprising at least one pair of deflection rollers and at least one pair of guide rollers, is pressed into the material to be cut such that it is guided in opposite directions in respectively two adjacent cuts in the block.
Patent CZ-72495-A3 (CZ)
Title: Method of transporting mortar, concrete and the like consistent materials and apparatus for making the same
Inventor: SCHLECHT KARL
IPC: B28C5/12
Filed: 1993-09-24
Abstract: A pneumatic conveyor for thick materials, such as mortar or cement, has a mixing tank (1) with a motor-driven mixing unit (2), a transport duct (24) connected to the mixing tank (1) next to its bottom, a lower air duct (14) and an upper air duct (15) which can both be charged with compressed air by means of a compressor (8, 11, 12). The upper air duct (15) opens into the upper area of the tank, whereas the lower air duct (14) opens at an injection spot into the transport duct (24). In order to make the apparatus easier to handle, to avoid operating errors and stoppers in the transport duct (24), and to reduce the actual transport time, the injection air supplied by the lower air duct (14) is turned on only when a predetermined minimum resistance is ascertained in the transport duct (24), whereas the compressed air supply to the tank (1) is blocked when a preset maximum resistance is reached in the transport duct.
Patent MA-38866-A3 (MA)
Title: Bioconjugués de polypeptides d'apeline synthétiques
Inventor: CAPLAN SHARI L
Filed: 2014-07-21
Abstract: L'invention concerne des bioconjugués comprenant un polypeptide synthétique de formule (i') ou un amide, un ester ou un sel de celui-ci, dans laquelle x1, x2, x3, x4, x5, x6, x7, x8, x9, x10, x11, x12 et x13 ont la signification indiquée dans la description et un fragment prolongeant la demi-vie, le peptide et le fragment prolongeant la demi-vie étant liés par covalence ou fusionnés, éventuellement par l'intermédiaire d'un lieur. Les polypeptides sont des agonistes du récepteur apj. L'invention concerne également un procédé qui permet de fabriquer lesdits bioconjugués, ainsi que leurs utilisations thérapeutiques, notamment dans le traitement ou la prévention de l'insuffisance cardiaque décompensée aiguë (icda), l'insuffisance cardiaque chronique, l'hypertension pulmonaire, la fibrillation auriculaire, le syndrome de brugada, la tachycardie ventriculaire, l'athérosclérose, l'hypertension, la resténose, les maladies cardiovasculaires ischémiques, la myocardiopathie, la fibrose cardiaque, l'arythmie, la rétention d'eau, le diabète (y compris le diabète gestationnel), l'obésité, la maladie artérielle périphérique, les accidents vasculaires cérébraux, les accidents ischémiques transitoires, les traumatismes cérébraux, la sclérose latérale amyotrophique, les brûlures (y compris les coups de soleil) et la prééclampsie. La présente invention concerne, en outre, une combinaison d'agents pharmacologiquement actifs et une composition pharmaceutique.
Patent SK-63297-A3 (SK)
Title: Method for separating substances from a gaseous medium by dry adsorption
Inventor: BJARNO ODD E
IPC: B01D53/10
Filed: 1995-11-22
Abstract: The treatment, through a dry adsorption process, of a gas from a hot electrolytic process for aluminium production comprises at least two stages (3, 4). Particulate aluminium oxide (the adsorbent) passes through the stages (3, 4) of the adsorption process contercurrently to the gas. Thus, the gas is treated with a partly spent adsorbent in a first dry adsorption stage, whereupon the particulate adsorbent is separated from the gas downstream from the first adsorption stage. Part of the separated particulate adsorbent is removed (33) from the adsorption process with a view to recycling adsorbed fluorine-containing substances to the electrolytic process. The remainder of the separated adsorbent is recirculated in the first adsorption stage in order to optimise the adsorption of fluorine-containing substances and the desorption of sulphur dioxide in this stage. Simultaneously, the gas is transferred to a second dry adsorption stage. In this second stage, the gas is treated with essentially unspent, reactive particulate aluminium oxide, so that any gaseous fluoride remaining in the gas is very efficiently adsorbed, while at the same time a substantial part of the sulphur dioxide in the gas is also adsorbed. Finally, this particulate aluminium oxide is separated from the gas downstream from the second dry adsorption stage, before the gas is discharged into the surrounding atmosphere. The separated aluminium oxide is transferred to the first adsorption stage, optionally after passing a desorption stage (8) for the removal of adsorbed sulphur dioxide in order to reduce the discharges of sulphur dioxide from the aluminium production. The separation of sulphur dioxide in the second adsorption stage is improved by recycling, to the second adsorption stage, aluminium oxide having undergone the desorption treatment.
Patent SK-88593-A3 (SK)
Title: Process and device for removing metal from flue dust
Inventor: AHRENS-BOTZONG RUDOLF
IPC: C22B7/02
Filed: 1992-02-12
Abstract: Process and device for removing metal (m) from flue dust (f). The flue dust (f) is introduced into a solution (L) containing a chelating agent (c) and the metal chelate ions formed from the metal in the solution (L) are removed from the solution. This is achieved using an electrolytic cell on whose cathode the elemental metal (m) is deposited. The flue dust (f) can be flue dust (f) from the flue gas (r) of a low-temperature combustor (40).
Patent CH-623448G-A3 (CH)
Title: Glass for watch
IPC: G04B39/00
Filed: 1977-06-09
Abstract: This glass is laminated and consists of layers of glass (4) between which are inserted sheets or films (5) of transparent organic material. <IMAGE>
Patent CZ-298392-A3 (CZ)
Inventor: KUBIS STANISLAV
IPC: F03D3/02
Filed: 1992-09-30
Abstract: Sestává ze skupiny lopatek (2) pootočitelně uspořádaných
na společném nosiči (1) otočně uloženém na stojanu (3).
Lopatky (2) jsou vůči sobě pootočené o polovinu vzájemné
úhlové vzdálenosti. Každá z lopatek (2)je opatřena ovládacím
ramenem (21). Na společném nosiči (1)je otočně uloženo
řízené rameno (4), které je spolu s ovládacími rameny
(21) propojeno táhly (5). Řízené rameno (4) je spojeno se
stojanem (3) kinematickou vazbou (6) o převodu 1:2
Patent CZ-100196-A3 (CZ)
Title: Device for controlling opening and closing jaws on a pressure cylinder
Inventor: CHAMEROY ERIC
IPC: A47J27/08
Filed: 1995-07-05
Abstract: The lid has a pair of radially-mounted jaws connected to a central actuating mechanism by a pair of transverse drive rods. A mobile control member (56) is located centrally on a control knob (50), for reciprocating movement in a direction radial to the knob and the lid.   Manual pressure moves the control member radially inwards, actuating the drive rods via a mechanical connection to move in a radially outward locking direction. The control member is linked to a control button (52), such that manual downward pressure on the button causes the control member to move radially outwards and the drive rods to move in a radially inward unlocking direction. The control member and button together form a central gripping handle for the lid. <IMAGE>
Patent CZ-108499-A3 (CZ)
Title: Autoclave
Inventor: THOBURN ROBERT JAMES
IPC: F16J13/24
Filed: 1997-09-23
Abstract: There is provided an autoclave (10) having a door (12) hingedly connected (at 13) to a vessel portion (11). A catch member (34) is provided for locking the door and the vessel portion, the catch member being biassed by spring (38) towards a locking position. The catch member is movable, preferably using a solenoid (36), out of said locking position.
Patent CZ-9901328-A3 (CZ)
Inventor: BURDA JIRI DIPL ING
IPC: H02K9/22
Filed: 1999-04-15
Abstract: Pro zvýšení výkonových parametrů elektrického stroje ve
vztahu k jeho zastavovacím rozměrům zlepšením odvodu
ztrátového tepla, je určen elektrický stroj, opatřený alespoň
jedním magnetickým obvodem (1), v němž jsou v pravidelném
odstupu od sebe souběžně vedené drážky (3) ve směru
příčném na směr jejich pořadí, ve kterých je uloženo vinutí (2)
pro vyvození magnetického pole volitelného počtu pólů
prostřídané polarity, časově i prostorově měnitelného ve
směru pořadí vytvoření drážek (3), přičemž vinutí je
galvanicky připojitelné na autonomní zdroj elektrické energie.
Dále je elektrický stroj opatřen alespoň jedním výměníkem (5)
tepla, pro odvod ztrátového tepla, vyvozeného v magneticky
a/nebo elektricky aktivních částech jemu příslušejícího
magnetického obvodu (1) alespoň mimo jeho zastavovací
prostor. V magnetickém obvodu (1) elektrického stroje je
každé drážce (3) z drážek (3) alespoň o počtu, odpovídajícím
počtu pólů magnetického poleje ve směrujejího vytvoření
uspořádána alespoň jedna teplovodná vložka (4) z plného
tepelně vodivého materiálu, jejíž alespoň jeden volný konec
(42), vystupující z magnetického obvodu (1), je v jeho
sousedství v tepelně vodivém styku s výměníkem (5) tepla.
Patent CZ-144897-A3 (CZ)
Title: Apparatus for detecting electric discharges within a tested object
Inventor: BENGTSSON TORD
IPC: G01R31/02
Filed: 1996-09-10
Abstract: A device for sensing electric discharges in a test object (1) with at least two electric connection conductors (1a, 1b, 1c, 1d) comprises transducer equipment and evaluation equipment (PA, ABU, LU). The transducer equipment comprises at least one transducer (6a, 6b, 6c, 6d) for direction-sensitive sensing of current pulses through the connection conductors by sensing a magnetic field, generated by the current pulses, and the polarity thereof. The transducer delivers a transducer signal (v1", v2", v3", v4", v11", v21") to the evaluation equipment in dependence on said current pulses and their direction. The evaluation equipment generates, in dependence on received transducer signals, an indicating signal (IND) indicating an electric discharge in the test object.
Patent CZ-157595-A3 (CZ)
Title: Novel peptides, process of their preparation and use
Inventor: HAUPT ANDREAS
IPC: A61K38/08
Filed: 1993-12-04
Abstract: Novel peptides of formula (I) in which R<1>, R<2>, X, A, R<3>, B, D, E, R<7>, M, Q, a, b and d have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
Patent CZ-200144-A3 (CZ)
Title: Compressor blow-off air circuit in gas turbine systems and relevant method
Inventor: ANAND ASHOK KUMAR
IPC: F02C7/32
Filed: 2001-01-04
Abstract: A gas turbine system that includes a compressor (12), a turbine component (14) and a load (16), wherein fuel and compressor discharge bleed air are supplied to a combustor (20) and gaseous products of combustion are introduced into the turbine component (14) and subsequently exhausted to atmosphere. A compressor discharge bleed air circuit removes bleed air from the compressor (12) and supplies one portion of the bleed air to the combustor (20) and another portion of the compressor discharge bleed air to an exhaust stack (30) of the turbine component (14) in a single cycle system, or to a heat recovery steam generator in a combined cycle system. In both systems, the bleed air diverted from the combustor may be expanded in an air expander (68) to reduce pressure upstream of the exhaust stack (30) or heat recovery steam generator. <IMAGE>
Patent CZ-212598-A3 (CZ)
Title: Inhalation apparatus
Inventor: ANDERSON GREGOR JOHN MCLENNAN
IPC: B65D83/06
Filed: 1996-12-19
Abstract: A powder inhalation device comprising a housing containing a pharmacologically active compound, a conduit (8) with an outlet extending into the housing through which a user can inhale to create an airflow through the conduit, a dosing unit (6,7) for delivering a dose of the compound to the conduit and baffles (9) arranged within the said conduit to aid disintegration of powder agglomerates entrained in said airflow. The baffles (9) comprise a plurality of staggered plates extending into the conduit from opposite sides of the conduit at an angle of less than 90 DEG  to the sides of the conduit and are inclined towards the outlet to create a plurality of constrictions within the conduit and a plurality of changes in the direction of the said airflow through the conduit. <IMAGE>
Patent CZ-234498-A3 (CZ)
Title: Aspartylprotease inhibitors, process of their preparation and preparation in which they are comprised
Inventor: TUNG ROGER DENNIS
IPC: C07D417/12
Filed: 1997-01-22
Abstract: This invention relates to a novel class of compounds of formula (I) that are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of aspartyl protease inhibitors characterized by specific structural and physicochemical features. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting HIV-1 and HIV-2 protease activity and consequently, may be advantageously used as anti-viral agents against the HIV-1 and HIV-2 viruses. This invention also relates to methods for inhibiting aspartyl protease activity and methods for treating viral infections using the compounds and compositions of this invention. A compound according to formula (I) wherein each Z is (a) or (b) or (c) wherein any Z may be optionally fused with R<6>; each X and X' is independently selected from the group consisting of C-C(O)-, -C(O)C(O)-, -S(O)- and -S(O)2; each Y and Y' is independently selected from the group consisting of -(C(R<2>)2)p-, -NR<2>-, -(C(CR<2>)2)p-M-, C=C(R<2>)2, and -N(R<2>)-CH2-.
Patent CZ-242097-A3 (CZ)
Title: Insulator with sealed joint and process for producing thereof
Inventor: KARL THOMAS
IPC: H01B17/00
Filed: 1996-01-19
Abstract: PCT No. PCT/EP96/00226 Sec. 371 Date Aug. 27, 1997 Sec. 102(e) Date Aug. 27, 1997 PCT Filed Jan. 19, 1996 PCT Pub. No. WO96/24144 PCT Pub. Date Aug. 8, 1996The invention relates to an electrical isolator having at least one fitting cemented onto an insulating body, in which the insulating body is bonded to the fitting via a cement shell, wherein a laminated layer which contains at least two layers of different materials is applied on the fitting between the cement shell and the fitting, wherein at least one of the layers protects the fitting from corrosion and wherein at least one other layer permits movement between the cement shell and the fitting.
Patent CZ-249995-A3 (CZ)
Title: Process and apparatus for for producing a binding agent
Inventor: ROSTOCK MARTIN
IPC: B02C17/06
Filed: 1994-01-25
Abstract: The invention concerns a method and device for the production of a binder made up of at least two components of different grindability.
Patent CZ-294295-A3 (CZ)
Title: Erivatives of aryloxycycloalkenyl hydroxy ureas and pharmaceutical compositions based thereon
Inventor: AKIYOSHI KAWAI
IPC: C07D215/20
Filed: 1995-11-09
Abstract: The present invention provides a compound of formula (I), wherein Ar is (a) phenyl, naphthyl and biphenyl, each optionally substituted with C1-4 alkyl, C1-4 haloalkyl, C1-4 hydroxyalkyl, C1-4 alkoxy, C1-4 haloalkoxy, C2-4 alkoxyalkoxy, C1-4 alkylthio, hydroxy, halo, cyano, amino, C1-4 alkylamino, di (C2-8) alkylamino, C2-6 alkanoylamino, carboxy, C2-6 alkoxycarbonyl, or optionally substituted phenyl, phenoxy, phenylthio or phenylsulfinyl or (b) furyl, benzo[b]furyl, thienyl, benzo[b]thienyl, pyridyl or quinolyl, each optionally substituted with C1-4 alkyl, C1-4 haloalkyl, halo, C1-4 alkoxy, optionally-substituted phenyl, phenoxy or phenylthio, X is C1-C4 alkylene, C2-C4 alkenylene, -(CHR<1>)m-Q<1>-(CHR<2>)n-, -O-(CHR<1>)jQ<2>- and -(CHR<1>)-O-N = in which the N = moiety is attached to the cycloakene ring; and in which Q<1> is O, S, SO, SO2, NR<3>, CH = N-O or CO, Q<2> is O, S, SO, SO2 or NR<3>, and R<1>, R<2> and R<3> are each hydrogen or C1-C4 alkyl, m and n are each an integer from 0 to 4 and j is an integer from 1 to 4; p is an integer of 1 or 2; Y is hydrogen, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, C2-4 alkoxyalkyl, C1-4 alkylthio, hydroxy, halo, cyano or amino; Z is hydrogen or C1-4 alkyl; and M is hydrogen, a pharmaceutically acceptable cation or a pharmaceutically acceptable metabolically cleavable group. Further the invention provides a pharmaceutical composition for treating a medical condition for which a 5-lipoxygenase inhibitor is needed in a mammalian subject which comprises a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. Preferably the medical condition is an inflammatory disease, allergy or cardiovascular diseases.
Patent CZ-358797-A3 (CZ)
Title: Lens with focal distance varying on the basis of small changes in the lens equatorial diameter
Inventor: SCHACHAR RONALD
IPC: G02B26/08
Filed: 1996-05-10
Abstract: A variable focus lens is constructed by making small changes in the equatorial diameter of an elastically deformable lens. The lens may be deformed by radial tension exerted in a plane generally perpendicular to the optical axis. The radial tension may be exerted by radially acting mechanical apparatus or by means of rings embedded or attached at the equator of the lens, whose diameter can be altered by heating, or by imposition of electrical or magnetic fields.