baber/WOPTO huggingface dataset:
Patent EP-1552020-B1 (EP)
Inventor: ERIKSSON MARIA B H
IPC: C07H21/04
Filed: 2003-10-17
Granted: 2012-02-29
Abstract: Disclosed herein are point mutations in the LMNA gene that cause HGPS. These mutations activate a cryptic splice site within the LMNA gene, which leads to deletion of part of exon 11 and generation of a mutant Lamin A protein product that is 50 amino acids shorter than the normal protein. In addition to the novel Lamin A variant protein and nucleic acids encoding this variant, methods of using these molecules in detecting biological conditions associated with a LMNA mutation in a subject (e.g., HGPS, arteriosclerosis, and other age-related diseases), methods of treating such conditions, methods of selecting treatments, methods of screening for compounds that influence Lamin A activity, and methods of influencing the expression of LMNA or LMNA variants are also described. Oligonucleotides and other compounds for use in examples of the described methods are also provided, as are protein-specific binding agents, such as antibodies, that bind specifically to at least one epitope of a Lamin A variant protein preferentially compared to wildtype Lamin A, and methods of using such antibodies in diagnosis, treatment, and screening. Also provided are kits for carrying out the methods described herein.
Patent EP-1584096-B1 (EP)
Inventor: DE AMBROGGI RENATO
IPC: H01H13/60
Filed: 2003-12-30
Granted: 2007-06-13
Abstract: L'invention concerne un interrupteur comprenant un contact électrique fixe (3.1) connecté à l'une des deux bornes de connexion (21.1). Un élément de connexion temporaire (4) métallique pivotant servant de culbuteur, présentant à l'une de ses extrémités un contact électrique mobile (5.1) et connecté électriquement à l'autre des deux terminaux (21.3), un organe d'actionnement (46) connecté à l'élément cavalier de façon à le faire osciller entre deux positions, une position dans laquelle le contact mobile (5.1) de l'élément cavalier (4) est en contact avec le contact électrique fixe (3.1). Afin d'actionner le bouton-poussoir, un élément de commande (47) pouvant tourner autour d'un deuxième axe (a2) parallèle au premier (al) comprend deux surfaces (36) conçues de manière symétrique par rapport à un plan contenant le second axe (a2), l'organe de commande (46) comprend un bouton-poussoir (42) mobile dans un sens selon des angles droits par rapport au deuxième axe (a2) en réponse à une pression appliquée sur ledit bouton-poussoir et un moyen de transmission de pression (8) connecté au bouton-poussoir (42) de façon à pouvoir tourner autour d'un troisième axe (a3), parallèle au premier axe (a1), maintenu dans une position prédéterminée par un élément élastique (22) et présentant deux extrémités (44) pouvant venir en contact de manière alternée avec les deux surfaces (36) de l'élément de commande (47) afin d'amener ce dernier dans une position angulaire ou une autre correspondant à l'une ou l'autre des positions prédéterminées de l'élément de connexion temporaire (4).
Patent EP-1458018-B1 (EP)
Inventor: MAEDA TAKENOBU
IPC: H01L21/60
Filed: 2004-01-26
Granted: 2006-04-19
Abstract: In an electronic component device, electrodes of an electric component and respective wiring lines(11,12) on a board(10A) are collectively bonded together via bumps(22) using ultrasonic vibration. The wiring lines(12) include wiring lines that are substantially parallel to the direction of ultrasonic vibration and wiring lines(11) that are substantially perpendicularly to the direction of ultrasonic vibration. A displacement inhibiting layer(13) is provided inside the board(10A) in a portion below the wiring lines(11) that are substantially perpendicular to the direction of ultrasonic vibration. <IMAGE>
Patent EP-1477518-B1 (EP)
Inventor: REICHWEIN DAVID P
IPC: D06N3/00
Filed: 2004-05-12
Granted: 2008-07-23
Abstract: Linoleum-based floor covering has linoleum layer(s) containing up to 40 wt.% inorganic silicon compound(s) (I) as flame retardant. Independent claims are also included for the following: (1) production of the linoleum-based floor covering by applying a linoleum mixture containing up to 40 wt.% (I) by means of calenders or roll coaters; (2) cork-based floor covering containing up to 40 wt.% (I); (3) use of (I) as flame retardant in linoleum- or cork-based floor coverings.
Patent EP-1509028-B1 (EP)
Inventor: OSUMI FUMIHIRO
IPC: H04M1/72436
Filed: 2004-08-05
Granted: 2006-04-26
Abstract: A control circuit activates a TV tuner to start reception of TV broadcast when a user selects a TV viewing mode. Subsequently, the control circuit monitors a remaining quantity of a battery, and instructs an LCD display to display such a message that the remaining quantity of the battery is less when the remaining quantity of the battery is less than 2/3. Then, the control circuit cuts the supply of an electric power to a mobile phone radio communication circuit when the user selects an operation mode to proceed to a power cut mode. When the control circuit detects that a TV broadcast program is shifted to a CM message, the control circuit turns on the supply of the electric power to the mobile phone radio communication circuit. Next, the control circuit makes an inquiry about whether or not there is an e-mail incoming call to a server. When there is the e-mail incoming call, the control circuit starts reception of the e-mail, and instructs the LCD display to display such a message that there is the e-mail incoming call. <IMAGE>
Patent EP-1617265-B1 (EP)
Inventor: WOLLESCHENSKY RALF
IPC: G01N21/64
Filed: 2004-10-01
Granted: 2006-12-13
Abstract: The light scanning microscope as several lasers of different colors whose beams are combined to make a scanning beam. The beam may be scanned over a microscope slide with stationary and moving objects. The various scans include a fine reference scan and four successive coarse scans. The scan lines of each scan lie in the spaces between the lines of the previous scan. A pictorial representation of the object under investigation has scan mechanism capable of coarse and fine scans which may be performed in turn to give high time and spatial resolution.
Patent EP-1655879-B1 (EP)
Inventor: LOEHR JOACHIM
IPC: H04W28/00
Filed: 2004-11-03
Granted: 2008-12-10
Abstract: The invention relates to a HARQ method using incremental redundancy and providing synchronous retransmissions. Further, the invention relates to a receiving entity and a transmitting entity employing the HARQ method and to a mobile communication system. To optimize conventional HARQ retransmission protocols, the invention introduces a feedback which allows requesting a self-decodable version of a data packet under certain conditions. Further, the feedback is provided in a backward compatible manner using a combination of conventional HARQ feedback signaling and scheduling related control signaling.
Patent EP-1462258-B1 (EP)
Inventor: NAKASHIMA ATSUHISA
IPC: B41J2/165
Filed: 2004-03-26
Granted: 2009-12-16
Abstract: Aprint head cap includes: a bottom surface; and a ring-like lip surrounding the bottom surface like a ring and protruding toward a nozzle surface of a print head of an ink jet printer and being elastically deformable. The ring-like lip is to be pressed onto the nozzle surface to cover the nozzle surface therewith. The ring-like lip has corners that change a direction of surrounding the bottom surface. The corners are more elastically deformable than the other portion of the ring-like lip. <IMAGE>
Patent EP-1623917-B1 (EP)
Inventor: YU JUN-HSIANG
IPC: B62K25/32
Filed: 2004-08-06
Granted: 2008-07-02
Abstract: The invention provides for an engine suspending device 6 for mounting an engine 4 on a frame 5, by way of two spaced-apart suspension lugs 40 associated with the engine 4, and including a positioning tube 64, and a mounting shaft (66) wherein the positioning tube (64) extends through first bearing assemblies 41 of the suspension lugs 40 and is disposed between second sleeves 6242, 6252 of first and second locking units. A mounting shaft 66 is inserted into the positioning tube 64 and the second sleeves 6242, 6252. The mounting shaft 66 has a first male screw thread 661 proximate to a bolt head 660 and arranged to engage the second sleeve 6252, a second male screw thread 662 which projects outwardly of the second sleeve 6242, and arranged to engage threadedly with a locking nut 67.
Patent EP-1466673-B1 (EP)
Inventor: LECLERC SYLVAIN
IPC: B08B15/00
Filed: 2004-04-01
Granted: 2008-03-05
Abstract: The process involves connecting a confinement at a non-polluted zone (12) of a Cowper type building (1) in a manner so that the confinement and an external metallic envelope (3) e.g. asbestos, of the building jointly form an enclosure. The enclosure insulates a zone, in which the pollution is to be controlled, from external atmosphere to prevent interior of the building from pollution.
Patent EP-1517442-B1 (EP)
Inventor: SAKAGUCHI KENJI
IPC: H03H9/25
Filed: 2004-08-27
Granted: 2009-10-28
Abstract: A surface acoustic wave device (50) includes a piezoelectric substrate (1), an interdigital transducer (IDT) electrode (2), and a connecting portion (3) that is electrically connected with the IDT electrode (2). The surface acoustic wave device (50) further includes a wiring portion (4), a portion of which is disposed on the connecting portion (3), and a bump (5) disposed on the wiring portion (4). The connecting portion (3) includes a comb-shaped portion (6) at an end of the connecting portion (3) on which the wiring portion (4) is disposed. <IMAGE>
Patent EP-1588154-B1 (EP)
Inventor: DAUTREY MIKAEL
IPC: G01M3/18
Filed: 2004-01-06
Granted: 2011-12-07
Abstract: Two blocks (4,5) have surfaces (1,2) which abut to form a joint with contact surface (3). The surfaces have conducting elements separated by insulated zones and the integrity of the joint may be tested by measuring (22) the electrical resistance along various lines between points (6,7). Any failure of integrity results in a variation of the resistance measured.
Patent EP-1594785-B1 (EP)
Title: Dispositif pour fabriquer et enrouler des fils synthetiques
Inventor: KIRCHHOFF BERND
IPC: D01D7/00
Filed: 2004-02-19
Granted: 2006-06-28
Abstract: L'invention concerne un dispositif pour fabriquer et enrouler des fils synthétiques. A cet effet, le dispositif comporte un dispositif de filage (1) servant au filage à chaud des fils, au moins un dispositif de traitement (7) servant au traitement des fils et un dispositif d'enroulement (16) servant à l'enroulement des fils, comportant plusieurs zones d'enroulement. Les zones d'enroulement (17. 1,17. 2, 17. 3) sont réparties le long de l'axe longitudinal horizontal du dispositif d'enroulement (16), un cylindre de guidage (12) entraîné et un guide-fil (15. 1, 15. 2, 15. 3) par zone d'enroulement servant à l'amenée des fils. Pour que des déviations différentes des fils soient évitées malgré des espaces différents séparant les fils pendant leur traitement et leur enroulement, il est prévu, selon l'invention que le cylindre de guidage (12) soit disposé de sorte que son axe soit vertical, à côté des guide-fils (15.1,15.2,15.3), les fils pouvant être ainsi guidés sensiblement en parallèle entre le cylindre de guidage (12) et les guide-fils (15.1,15.2.15.3).
Patent EP-1723639-B1 (EP)
Inventor: LAKANIEMI ARI
IPC: G10L19/008
Filed: 2004-03-12
Granted: 2007-11-14
Abstract: The invention relates to a method of synthesizing a mono audio signal 3 based on an available encoded multichannel audio signal 2. The encoded multichannel audio signal 2 is assumed to comprise at least for a part of an audio frequency band separate parameter values for each channel of the multichannel audio signal. In order to reduce the processing load in synthesizing the mono audio signal 2, it is proposed that the parameter values of the multiple channels are combined at least for a part of an audio frequency band in the parameter domain. The combined parameter values are then used for synthesizing the mono audio signal. The invention relates equally to a corresponding audio decoder, to a corresponding coding system and to a corresponding software program product.
Patent EP-1622480-B1 (EP)
Inventor: CECCARINI MARCELLO
IPC: A45D29/22
Filed: 2004-05-04
Granted: 2006-11-22
Abstract: A device for beauty treatment of limbs includes at least: a first support ( 2 ) for at least one limb portion fit for allowing an operator to operate on said portion by using tools, products and material; aspirator means ( 3 ) fit to suck air with powders and/or vapors of products used for the beauty treatment of limbs and fit to reintroduce the purified air in the environment; a set of lamps ( 4 ) for the treatment of the limb portion or for working on products applied to the limb.
Patent EP-1638964-B1 (EP)
Inventor: CLARY LAURENCE
IPC: C07D417/12
Filed: 2004-06-16
Granted: 2011-07-27
Abstract: La présente invention concerne de nouveaux composés correspondant à la formule (I). La présente invention concerne également un procédé pour préparer ces composés, ainsi que leur utilisation dans des compositions pharmaceutiques utilisées dans le domaine de la médecine pour les hommes ou les animaux (en dermatologie, mais également dans le domaine des maladies cardiovasculaires, des maladies immunes et/ou des maladies associées au métabolisme des lipides) ou, en variante, dans des compositions cosmétiques.
Patent EP-1631314-B1 (EP)
Inventor: MCINTYRE JOHN A
IPC: C07K16/18
Filed: 2004-06-09
Granted: 2011-08-03
Abstract: The binding specificity of at least one plasma protein suspended or dissolved in a liquid medium is altered by exposing the protein to an oxidizing agent or an electric current sufficient to alter its binding specificity. A masked protein such as an autoantibody can be recovered from blood or blood products or extracts by oxidizing the protein to change its binding specificity.
Patent EP-1635727-B1 (EP)
Inventor: JUNJIE HAO
IPC: A61B19/04
Filed: 2004-06-18
Granted: 2007-03-07
Abstract: A disposable glove for a hand of a human wearer that comprises polyvinyl chloride (PVC) and is substantially impermeable to liquid water. The glove provides an elastic material with superior restore rate and elasticity parameters, while maintaining good tensile strength.
Patent EP-1663359-B1 (EP)
Inventor: HARMER QUENTIN
IPC: A61M15/00
Filed: 2004-09-15
Granted: 2010-11-17
Abstract: A dry powder inhaler (1) for delivering a dose of medicament for inhalation by a user is disclosed. The inhaler comprises a drug entrainment device including a drug outlet tube (23) terminating with a primary piercing element (24) to pierce an opening in a lid (12b) when a pack is located in the inhaler, a secondary piercing member (26) to pierce a plurality of peripheral openings in said lid and, an airflow path to enable the supply of a charge of gas into the pack via said peripheral openings to scour the interior of a pierced pack such that substantially all of the dose is entrained in the gas and flows out of the pack via the drug outlet tube. The secondary piercing member is configured to form a substantially circular pattern or ring of openings in the lid of a blister.
Patent EP-1776354-B1 (EP)
Inventor: PARTHASARADHI REDDY BANDI
IPC: C07D311/58
Filed: 2004-08-11
Granted: 2010-04-21
Abstract: The present invention relates to a process for separation of desired diastereomeric pair from a mixture of diastereomeric pairs thereby obtaining nebivolol intermediates. Thus, the mixture of (+)-[1S*(R*)]-6-fluoro-3,4-di-hydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol, (+)-[1S*(S*)]-6-fluoro-3,4-dihydro-2-oxi -ranyl-2H-1-benzopyran and ethanol is heated to reflux temperature and stirred for 8 hours at the same temperature to obtain (±)-[2R*[1S*,5S*(S*)]]+[2R*[1S*,5R*(R*)]]-alpha,alpha'-[phenylmethyliminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran ran-2-methanol]. Then the reaction mass is cooled to 10° C., the pH is adjusted to 2 with HCl gas and stirred for 45 minutes at 25° C. to 30° C. Then the separated solid is filtered and dried to give (+)-[2R*[1S*,5S*(S*)]]-alpha,alpha'-[phenylmethyliminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] hydrochloride salt, which can be converted into nebivolol.
Patent EP-1673502-B1 (EP)
Inventor: SANTICCHI AUGUSTO
IPC: D06F93/00
Filed: 2004-10-05
Granted: 2006-12-27
Abstract: This invention concerns a system for the identification and the sorting in a predetermined order of single garments or laundry items, of the sort that uses a box ( 1 ) suitable for reading chips sewn on garments introduced inside the box ( 1 ), characterized by the fact that the said box is connected at its top extremity with the straight ascending section ( 2 a) of a large conveying pipe ( 2 ), while underneath it has a base ( 5 ) with a grating structure ( 5 ), associated with a fan ( 6 ) suitable for blowing into the box ( 1 ) itself a powerful air blast which can give the garments found in the box ( 1 ) an upthrust, that enables them to enter the above-mentioned conveying pipe ( 2 ) placed above and to pass through its whole length ( 2 a, 2 b, 2 c) until they are unloaded into suitable bins (c 1 , c 2 , c 3 ) placed under the pipe's outlet segment ( 2 c).
Patent EP-1687062-B1 (EP)
Inventor: WARKENTIN DWIGHT H
IPC: A61N1/362
Filed: 2004-10-07
Granted: 2011-12-21
Abstract: An implantable cardiac stimulation device capable of delivering ESS, monitoring for myocardial ischemia and responding to the detection of myocardial ischemia by modifying the delivery of ESS. Modification of ESS delivery may include disabling ESS, initiating ESS, and/or modifying ESS control parameters.
Patent EP-1689659-B1 (EP)
Inventor: HUXTABLE PAUL STEWART
IPC: A47B47/00
Filed: 2004-11-18
Granted: 2010-06-16
Abstract: The invention relates to a protecting apparatus (10) for protecting a structure (100) from an impact. The protecting apparatus (10) is arranged to be mounted on the structure (100) and includes a bumper member (12), a structure positioning member (14) and at least one resiliently flexible joining portion (16). The structure positioning member (14) is arranged in use to be positioned in contact with or adjacent to a portion of the structure (100) being protected. The at least one resiliently flexible joining portion (16) extends between the bumper member (12) and the structure positioning member (14) so that when an outer surface (12a) of the bumper member (12) is impacted, the impact force is dissipated at least in part by flexure of the at least one joining portion (16).
Patent EP-1696735-B1 (EP)
Inventor: KHOO CHRISTINA
IPC: A23L33/15
Filed: 2004-12-03
Granted: 2009-10-14
Abstract: A composition suitable for mammalian oral ingestion in a mammal having GI tract inflammation comprising an anti-diarrhea effective amount of glutamine, fermentable fiber(s), antioxidant(s), and omega-3 fatty acid(s).
Patent EP-1802270-B1 (EP)
Inventor: DAL FARRA CLAUDE
IPC: A61K38/02
Filed: 2004-12-23
Granted: 2010-12-22
Abstract: Proteins of the uncoupling protein (UCP) family or fragments thereof used as active ingredients in cosmetic or dermatological compositions, are new. Independent claims are also included for: (1) cosmetic, dermatological or pharmaceutical composition comprising a peptide as above; (2) cosmetic care method for reducing, eliminating or preventing excess subcutaneous fat and/or combating cellulite and/or combating the orange peel effect, comprising applying a composition as above to the skin. ACTIVITY : Dermatological; Anorectic. No biological data given. MECHANISM OF ACTION : Lipogenesis inhibitor. Pro-Leu-Asp-Thr-Ala-Lys-Val-Arg-Leu-Gln (0.5% of a 50 ppm solution) was added to cultures of 3T3-L1 pre-adipocyte cells before differentiation. On staining with oil red, the cells showed lower levels of lipid vesicles than control cells. No effect was observed if the peptide was added after differentiation.
Patent EP-1683622-B1 (EP)
Inventor: ONISHI MASASHI
IPC: B29C48/475
Filed: 2004-11-12
Granted: 2011-05-11
Abstract: An induction-heating-type heating apparatus is attached to an area of the outer circumference of a heating cylinder adjacent to a cooling apparatus, whereby the temperature of the heating cylinder can be uniformly controlled to a proper value, and the temperature of the heating cylinder can be changed quickly. An injection apparatus is adapted to intermittently feed forward a resin within a heating cylinder by a screw in accordance with an injection molding cycle. The injection apparatus includes a cooling apparatus attached to a rear portion of the heating cylinder, and an induction heating apparatus attached to the heating cylinder to be located forward of the cooling apparatus and adjacent to the cooling apparatus.
Patent EP-1830836-B1 (EP)
Inventor: MEYER DOMINIK
IPC: A61K31/165
Filed: 2004-12-22
Granted: 2010-11-24
Abstract: The following abstract will replace all prior versions of the abstract in the application: The mixture comprises a vanilloid receptor agonist with a substance, which inhibits nerve regeneration. The mixture is suitable for use, especially, as a painkiller.
Patent EP-1586342-B1 (EP)
Inventor: KIRCHHOFER FRITZ
IPC: A61M5/48
Filed: 1999-05-07
Granted: 2007-01-03
Abstract: An arrangement for administering an injectable product comprises a base (4,7), a container (1) for a product, which can be ejected via a needle using a piston (2), and a drive unit with a drive element (40). Damping members (42,50) exert a damping force when the piston is pushed forwards.
Patent EP-1683827-B1 (EP)
Inventor: KIJIMA SEIJI
IPC: C08J9/00
Filed: 2005-12-22
Granted: 2011-12-14
Abstract: Open-cell foam of ethylene-propylene-diene rubber that can convert to open-cell foams at the foaming of EPDM, rather than after the foaming of the same, and can produce low impact resiliency and improved filling capability. After 0.1·40 parts by weight of organic foaming agent, 2-40 parts by weight of inorganic foaming agent, and 2-40 parts by weight of foam auxiliary agent per 100 parts by weight of ethylene-propylene-diene rubber are mixed, the mixture is vulcanized and foamed to thereby produce open-cell foam of ethylene-propylene-diene rubber. This open-cell foam of ethylene-propylene-diene rubber has low impact resilience and good sealing performance so that it can be used as sealing materials of a variety of industrial products.
Patent EP-1574323-B1 (EP)
Inventor: KRUEGER FRANK
IPC: B31B50/25
Filed: 2005-02-21
Granted: 2011-06-08
Abstract: The grooving part (10), shaped as a ring segment, has an indentation (18) around its periphery and radial flexible side walls (19). The side walls of the indentation are round on their upper edge and made of plastic. The base of the indentation is made of a fixed core (12) and its side walls are formed by grooved lips (14) attached to the core, which bend in the direction indicated (31). The grooves are made in the object (1) when the grooving part is pushed against the tool (20) bending the lips apart.
Patent EP-1615250-B1 (EP)
Inventor: HALLET MICHEL
IPC: H01H25/06
Filed: 2005-05-16
Granted: 2008-11-26
Abstract: The device has a control unit (2) displaced between working positions and a rest position, where a longitudinal axis of the unit is coaxial with a rotation axis of a fixed indexing unit (3) and active sides of fixed and movable indexing units (3, 4) are parallel. The longitudinal axis is spaced angularly from the axis of the unit (3) and the active sides do not magnetically contact with each other in the working positions.
Patent EP-1667404-B1 (EP)
Inventor: KALER CHRISTOPHER G
IPC: G06F40/143
Filed: 2005-11-08
Granted: 2009-06-03
Abstract: A mechanism for sending structured data using a corresponding byte stream. Upon accessing structured data such as a Simple Object Access Protocol (SOAP) envelope, a byte stream is generated. The byte stream includes bytes that represent the structured data, as well as a collection of bytes that represents properties about the byte stream such as, for example, a mode of communication. The byte stream may then be passed to a communication module (e.g., a TCP or Named Pipes module) capable of receiving and transmitting the byte stream.