baber/WOPTO huggingface dataset:
Patent CA-2540174-A1 (CA)
Inventor: SCHMIDT FRIEDRICH
IPC: A61K31/4745
Filed: 2004-09-21
Abstract: L'invention concerne des préparations pharmaceutiques à inhaler, contenant comme seul principe actif un composé de formule (I) dans laquelle X?- ¿représente un anion sélectionné de préférence dans le groupe comprenant le chlorure, le bromure, l'iodure, le sulfate, le phosphate, le méthane sulfate, le nitrate, le maléate, l'acétate, le nitrate, le fumarate, le tartrate, l'oxalate, le succinate, le benzoate et le p-toluène sulfonate. Ces préparations contiennent comme solvant de l'éthanol ou des mélanges d'éthanol et d'eau, ainsi qu'au moins un acide pharmacologiquement tolérable et éventuellement d'autres auxiliaires et/ou agents complexants pharmacologiquement tolérables.
Patent CA-2541015-A1 (CA)
Title: Igf binding proteins
Inventor: LOWMAN HENRY
IPC: C12P21/04
Filed: 2004-09-08
Abstract: IGFBP-3 fusion proteins are provided that are useful, for example, in cell-based assays, as IGF antagonists, and in mapping IGF-I and IGF-II binding sites on other molecules such as wild-type IGFBP-3 and IGF agonist peptides identified by phage display. Methods for making such fusion proteins are also provided.
Patent CA-2542422-A1 (CA)
Title: Carrier search methods and apparatus
Inventor: LAROIA RAJIV
IPC: H04B1/713
Filed: 2004-10-15
Abstract: Transmitting signals to facilitate detection of a frequency band (406) and/or carrier signal to be used for communication with a basestation are described.  The detected frequency band may be a downlink frequency band (420). The uplink frequency band (424) to be used can be determined from a know frequency relationship between the detected downlink carrier and a corresponding uplink carrier or by monitoring the detected downlink frequency band for information indicating the uplink frequency band/carrier to be used. Carrier search methods (402) involving searching for the narrowband high power signals (404) used to provide carrier information and/or to indicate the frequency band (406) to be monitored are described. Power detection methods can be used to detect the high power signals avoiding the need for symbol timing synchronization and/or channel estimation with regard to detection of the signals used to locate the frequency band to be used.
Patent CA-2545294-A1 (CA)
Title: Tetronic and tetramic acids as inhibitors of beta-secrease
Inventor: ROGERS-EVANS MARK
IPC: C07D495/06
Filed: 2004-11-22
Abstract: This invention relates to new tetronic and tetramic acid derivatives with beta-secretase inhibitory activity of formula (I), wherein RI, R2, R3, R4, R5, R5', R6 and R6' areas defined hereinabove, to processes for their preparation, compositions containing said tetronic and tetramic acid derivatives and their use in the treatment and prevention of diseases modulated by an inhibitor of .szlig.-secretase, such as Alzheimer's disease.
Patent CA-2547051-A1 (CA)
Inventor: ENDRIKAT JAN
IPC: A61K31/57
Filed: 2004-11-20
Abstract: A pharmaceutical preparation to obtain a continuous hormonal treatment over a desired period of time longer than 21-28 days comprising a first composition containing at least one estrogen and/or at least one progestin in a predetermined amount to be administered in the first 21-28 days and a second composition which contains at least one estrogen and/or at least one progestin in a predetermined amount higher than the amount of the first composition and comprises a mono or multiphase sequence of pharmaceutical dosages.
Patent CA-2548309-A1 (CA)
Title: Aryl sulfonamide compounds and uses related thereto
Inventor: YAN XUELEI
IPC: C07D403/06
Filed: 2004-12-20
Abstract: The present invention provides Aryl Sulfonamide Compounds having the formula:  (I); and prodrugs or pharmaceutically acceptable salts or prodrugs thereof.  The Aryl Sulfonamide Compounds are useful for treating diabetes, obesity, and other diseases and disorders.
Patent CA-2548626-A1 (CA)
Inventor: MALAN DANIEL
IPC: F24H9/20
Filed: 2006-05-29
Abstract: A self-calibrating, self-teaching, self-diagnostic Micro-controller managed Pressure Monitored Flow Management and Flow Control System to detect and prevent leaks and burst on Hot Water Tanks and other alike fluid-intake utilities. The System includes a Processing Control unit that consists of a micro-controller, receiving signals from pressure & temperature transducer systems; and from an ambient temperature recording system; and from moisture-sensing devices; and/or from smoke recording devices, and/or from gas recording devices.     The micro-controller using signals from devices mentioned above, determines upstream and downstream pressures and temperatures, floor moisture levels, temperature gradients and will supply water by opening valves to and from the Hot Water Tank and other alike fluid-intake utilities when all conditions are operationally sound to supply water. The system will shut flow to the Hot Water Tank and alike utilities in the event of a leak of burst or in the event of a extreme temperatures, create visual and audible signals and send a signal to an installed alarm system.
Patent CA-2549235-A1 (CA)
Inventor: PEARCE RICHARD A
IPC: F04D29/64
Filed: 2006-06-01
Abstract: A ceiling fan hanging system (10) in disclosed for use with a conventional ceiling fan (11). The hanging system includes a ceiling mounting plate (17), a canopy mounting plate (18), a canopy (19), and a canopy trim ring (20). A male electrical connector (32) is fixedly mounted to the ceiling mounting plate. The male electrical connector which mates with the female electrical connector (51) is mounted to a slide (46) mounted for reciprocal movement upon the canopy mounting plate. The slide has two arm (47) and a central push plate or tab (48). Each arm is configured to be releasably received within a mounting plate loop (27) extending from the ceiling mounting plate and extending through a loop opening (43). The structural electrical wires are electrically coupled to the male electrical connector while the ceiling fan electrical wires are electrically coupled to the female electrical connector. The ceiling fan is mounted to the ceiling in an efficient manner by engaging the slide and moving the female electrical connector into electrical contact with the male electrical connector.
Patent CA-2550471-A1 (CA)
Title: Rail-guided transport system
Inventor: ROSSMANN MARTIN
IPC: B61L23/00
Filed: 2004-08-10
Abstract: The invention relates to a rail-guided system for transporting persons and material in underground mining and tunnel construction. Said rail-guided transport system comprises a railroad network and transport vehicles that are guided in said railroad network. The inventive transport system is characterized in that both the forward end and the opposite end of the respective transport vehicle are equipped with sensors (1-6) for detecting optical, acoustic, thermal, and acceleration data, "forward" being relative to the direction of travel. Said sensors (1-6) are connected to a control computer that is disposed inside the transport vehicle while interacting with active and passive transducers located within the railroad network.
Patent CA-2550854-A1 (CA)
Inventor: SALA RAFAEL FERNANDO
IPC: C12Q1/68
Filed: 2004-12-29
Abstract: The present invention provides a thiosulfonate-activated ionophore comprising an ionophore, a spacer group, and an alkylthiosulfonate moiety. A preferred ionophore is gramicidin A. A preferred alkylthiosulfonate is methanethiosulfonate. The present invention also provides a conjugate comprising an ionophore, a spacer group, and a recognition molecule. Further the invention related to membranes incorporating the conjugates and biosensors comprising said membranes.
Patent CA-2552544-A1 (CA)
Inventor: TUONONEN MARTTI
IPC: H01H9/00
Filed: 2005-01-18
Abstract: A modular switching device comprising a plurality of interconnected modules (2, 3), said modules comprising a control device module (2) and a pole cell module (3), said modules (2, 3) of the switching device being interconnected with a shaft adapted to transfer a torque required for operating the switchi ng device from one module (2) to another module (3). The modular switching de- vice of the invention is characterized in that each module (2, 3) comprises a shaft element (6), and in that said shaft transferring the torque is compose d of directly interconnected shaft elements (6).
Patent CA-2552753-A1 (CA)
Title: Meat marinade comprising fat and protein and snack-size meat pieces
Inventor: VAN GOOR JOHANN WILHELM
IPC: A23L13/40
Filed: 2005-01-07
Abstract: This invention relates to a process for improving the texture and juiciness of a meat product intended for cooking, among others of those intended for frying. In particular, the invention relates to a novel marinade for improving the tenderness and mouthfeel of a meat product. Provided is a meat marinade comprising a fat and a protein wherein said fat is present in an amount of about 0.1 -25 percent by weight (w%) of the marinade, preferably 0.3-20 w%, more preferably 0.5-10 w%, and wherein said protein is present in an amount of about 0.05 -10 percent by weight (w%) of the marinade, preferably 0.8 - 6 w%, more preferably 1-5 w%. Said marinade may comprise a fat- and protein-containing dairy product, such as cooking cream. Also provided is a method for improving the tenderness of a meat product, comprising marinating said meat product with a marinade according to the invention.
Patent CA-2554504-A1 (CA)
Title: Method and apparatus for excising skin
Inventor: GIOVANNOLI JOSEPH
IPC: A61B17/32
Filed: 2005-01-21
Abstract: A method for excising skin is disclosed, in which a plurality of incisions are made to collectively form a patch of skin to be reduced, instead of making a single large incision of the patch. Thus, scarring after healing is less noticeable. Preferably, the incisions are arranged such that a total area of all incised skin segments taken in a direction perpendicular to an axis of said patch changes gradually along said axis. The incisions are preferably navicular in shape, and the patch axial ends are are preferably navicular in shape in the event an elongated incision is made. A punch array is also disclosed for making the incisions simultaneously and precisely.
Patent CA-2554735-A1 (CA)
Inventor: RATHJEN DEBORAH ANN
IPC: C07C233/49
Filed: 2005-01-28
Abstract: The present invention relates generally to compounds comprising a hydrocarbon chain portion and more particular to compounds comprising chemical derivatizations of the hydrocarbon chain which are useful therapeutic and prophylactic molecules. The present invention further provides compounds where the hydrocarbon chain portion is a carrier molecule for functional groups, moieties or agents. The compounds of the present invention are particularly useful in the treatment and prophylaxis of a range of conditions including cancers, protein kinase c(PKC)- or NFkB-related- or -associated conditions, cardiovascular conditions, pain, inflammatory conditions, vascular or immunological conditions such as diabetes, neurological conditions and infection by a range of viruses or prokaryotic or eukaryotic organisms. The present invention further provides pharmaceutical compositions and methods of medical treatment.
Patent CA-2555939-A1 (CA)
Title: Treatment of abnormalities of the first metatarsophalangeal joint of the foot
Inventor: RADOVIC PHILIP
IPC: A61K38/48
Filed: 2005-02-11
Abstract: Disclosed is a use of a neuromuscular toxin in the preparation of a medicament for the treatment of abnormalities of the first metatarsophalangeal joint of the foot of a mammal. Preferred embodiments include use of toxins capable of interfering with the connection between muscle and nerve, e.g. botulinum toxin, in the preparation of medicaments to treat such abnormalities as hallux abductovalgus, hallux varus, hallux limitus, and hallux rigidus.
Patent CA-2558765-A1 (CA)
Inventor: PICHON PHILIPPE
IPC: E04H4/16
Filed: 2005-04-13
Abstract: The invention relates to an immersed surface cleaning device comprising a filtering chamber (6) provided, through a lower rigid wall (8), with at least one liquid inlet (9a, 9b) which has a non-return unit, at least one filter (7) remote from each liquid inlet (9a, 9b) in such a way that a solid impurities retaining area (12) is defined and with a hydraulic circuit for forming a liquid flow by pumping means (4). At least one non-return unit comprises an anti-return conduit (20) which extends through the retaining area (12) away from the liquid inlet and whose free end (21) enters said retaining area (12), wherein the conduit is used for preventing at least the passage of impurities in an opposite direction from the retaining area through the liquid inlet at least when said pumping means is unused.
Patent CA-2560090-A1 (CA)
Title: Signal activated fastener array
Inventor: RUDDUCK DICKORY
IPC: H05K7/14
Filed: 2005-03-16
Abstract: The invention provides a fastening system (40) which includes a plurality of fasteners (12). Each fastener (12) is adapted to be locked or unlocked upon receipt of a suitable signal, such as an electric, magnetic or infrared signal. The fasteners (12) are included in a single carrier (38).
Patent CA-2560274-A1 (CA)
Title: Reclosable passageway in slider for reclosable bag
Inventor: ARMSTRONG STEPHEN G
IPC: B65D30/24
Filed: 2005-03-17
Abstract: The present invention provides a slider (20) for opening and closing a bag opening (16) of a bag (10), wherein the bag opening (16) has opposed interlocking features (18), the slider (20) comprising a movable body (38) in the bag opening (16), between the opposed interlocking features (18), to engage and disengage the interlocking features (18) as the body (38) moves, a passageway (26) in the body (38), to provide access between an interior of the bag (14) and an area outside of the bag (28); and a valve (80) for selectively opening and closing the passageway (26) and to provide an access through the passageway (26) between the bag interior (14) and the outside of the bag (28).
Patent CA-2561094-A1 (CA)
Inventor: BLACK NEVILLE A
IPC: H04N7/16
Filed: 2005-02-21
Abstract: A video-on-demand (VOD) method and System for use with a computer connected to the Internet includes an Internet website. The website lists videos available for delivery from a content provider to a cable provider subscriber. The subscriber uses the computer to select a video from the website. The cable provider receives the selected video from the content provider and then delivers the video to a television of the subscriber via the cable television network. The subscriber uses the computer to register an interest profile on the website. Information regarding the available videos is compared with the profile and an email is then sent to the subscriber via the Internet. The email contains information regarding the available videos corresponding to the profile. The subscriber requests a video identified in the email for delivery from the content provider to the television via the cable television network.
Patent CA-2568792-A1 (CA)
Title: Optical coupling device
Inventor: YABRE GNITABOURE
IPC: G02B6/43
Filed: 2005-06-07
Abstract: The object of the invention is an optical coupling device between at least one waveguide (6) embedded in a printed circuit (3), for conveying an optical beam (F), and an external waveguide (2), the circuit (3) comprising, starting from an exterior surface (4 ) of the circuit, at least one insulating first layer (5) and at least one internal layer incorporating at least one core (1) of embedded waveguide (6) forming said optical path, the device comprising a coupling element (9), positioned in a cut (8), hollowed out in the circuit (3) and cutting the embedded waveguide (6), the coupling element (9) being furnished with means of refocussing of the optical beam between the embedded waveguide (6) and the external waveguide (2) and at least one lower positioning surface (13) on a reference surface (11) of the cut (8) in relation to the axis of the embedded waveguide (6).
Patent CA-2569698-A1 (CA)
Title: The importance of the gene hoxb13 for cancer
Inventor: SGROI DENNIS C
IPC: C12Q1/68
Filed: 2005-06-03
Abstract: This invention relates to the detection of increased expression from the HoxB13 (homeobox B13) gene as indicative of an invasive or metastatic cancer phenotype. The invention provides methods of detecting the level c expression from the HoxB13 gene, optionally in combination with nodal status, as an indicator of the invasive or metastatic phenotype as well as increased cellular migration and/or mobility. The invention also provides for the measurement of expression from the HoxB13 gene to assist in the determination of patient prognosis as well as clinical diagnosis and treatment.
Patent CA-2571119-A1 (CA)
Inventor: MIXON MARK B
IPC: C30B28/06
Filed: 2005-06-28
Abstract: The present invention provides computer-implementable systems and methods for generating images of crystals. The systems each include (a) a light source;  (b) a rotatable first polarizing material; (c) a rotatable second polarizing material; (d) a light-capturing device; and (e) a software program executable on the computer-implementable system for analyzing electrical signals from the light-capturing device.
Patent CA-2571176-A1 (CA)
Title: Method and apparatus for removal of flashing and blockages from a casting
Inventor: FRENCH IAN
IPC: B22D29/00
Filed: 2005-06-27
Abstract: A method of producing a metal casting comprising : pouring a molten metal material into a mold to form a casting having a core aperture ; removing the casting from the mold ; at least partially clearing the core aperture of the casting; and heat treating the casting.
Patent CA-2571211-A1 (CA)
Inventor: BORCHARDT MICHAEL G
IPC: B65D33/25
Filed: 2005-06-23
Abstract: A closure device includes a spring member to increase the sealing action of the closure device. The closure device is particularly suitable for use with flexible containers. The closure device includes a male and a female closure element that include male and female hook portions, respectively. The male and female hook portions interlockingly engage with one another to provide a leak proof seal for the flexible container. The spring member is attached to one of the closure elements and acts upon the hook portions of the other closure element to increase the sealing action of the closure device.
Patent CA-2571402-A1 (CA)
Title: Method of and system for managing and reporting mortgage transactions over the world wide web
Inventor: DE SENA FRANCIS E
IPC: G06Q40/02
Filed: 2006-12-15
Abstract: A system and method for web-based mortgage/loan reporting and management are provided. A electronic mortgage is created. The mortgage is reported to parties involved. A funds request can be sent to a funding party such as a financial institutions. When a funding acknowledgement has been received a final mortgage report is generated and sent to the relevant parties for confirmation of completion of the mortgage.
Patent CA-2571528-A1 (CA)
Inventor: EPPELMANN KATRIN
IPC: C12N9/10
Filed: 2005-07-11
Abstract: The invention relates to a process for biochemical synthesis of 1,4-butanediamine in a microorganism having an increased level of an ornithine decarboxylase activity (increased ODC activity) as compared to the native level of the ornithine decarboxylase activity, wherein in the microorganism also an increased activity of N-acetylglutamate formation is present as compared to the native level of activity of N-acetylglutamate formation in the microorganism and wherein 1,4-butanediamine produced in the microorganism is excreted into a fermentation broth, and is recovered from the fermentation broth. The invention also relates to vectors, plasmids and hosts carrying a corresponding increased ODC activity and an increased activity of N-acetylglutamate formation.
Patent CA-2573145-A1 (CA)
Inventor: CORRADINI FABIO
IPC: C11D3/20
Filed: 2005-07-08
Abstract: This invention relates to a method of removing and preventing the deposition of hard water scale in a clothes washing machine. In particular the method relates to the removal of and prevention of scale build up after the main wash of a clothes washing machine, by use of an acidic composition. The invention also relates to water-softening compositions for such methods.
Patent CA-2574993-A1 (CA)
Inventor: MONTELLATO RANDY
IPC: A61M5/28
Filed: 2005-07-22
Abstract: An injection syringe (100) comprises a barrel having a distal end and a proximal end; and finger member(s) non-slidably attached to a distal portion of the barrel. The finger member is configured to permit application of a force by one or more fingers of a person's hand such that the syringe is urged in a distal direction. Independent claims are also included for: (1) a medical reconstitution system (200) for a composition (50) comprising mixable first and second constituents (30, 40), comprising a receptacle (20) containing the first constituent; and a syringe containing the second constituent; (2) delivering a multi-constituent composition for injection, comprising providing a first constituent in a receptacle having a pierceable seal, a piercing member (25) movable between a retracted position and a fully-pierced position, and a first connector (27) in fluid communication with the piercing member; providing a second constituent in an injection syringe having finger member(s) proximate to a distal end of the syringe, and having a second connector on the distal end of the syringe; connecting the first and second connectors while the piercing member is in the retracted position; displacing the piercing member from the retracted position to the fully-pierced position by pushing the distal finger member (150) toward the receptacle, thus causing the piercing member to pierce the seal; injecting the second constituent from the syringe into the receptacle through the first and second connectors and the piercing member; causing the first and second constituents to mix together in the receptacle to form the composition; and drawing the composition into the syringe from the receptacle through the piercing member and through the first and second connectors; and (3) a distal finger brace for a hypodermic syringe having a barrel with a proximal end and a distal end, comprising a central bore sized and configured to receive a portion of the syringe barrel proximate to the distal end of the barrel; a lip configured to positively engage the distal end of the barrel; and outwardly extending finger tab(s). The receptacle comprises a container including a pierceable seal; a piercing member configured to selectively pierce the pierceable seal, and being operable between a retracted position and a fully pierced position; a first connector connected to and in fluid communication with the piercing member; and a sterile shield (28) surrounding the seal and the piercing member. The syringe comprises a barrel having a distal end, a proximal end, and a second connector on the distal end, where the second connector is configured to engage the first connector of the receptacle and provide a fluid-tight connection with the first connector; and the finger member(s). When the piercing member is in the retracted position and the first and second connectors are sealingly engaged together, the piercing member is capable of being advanced to the fully-pierced position by pushing and displacing the finger member in the distal direction toward the receptacle.
Patent CA-2575265-A1 (CA)
Title: Combination compositions comprising 13-cis-retinyl derivatives and uses thereof to treat ophthalmic disorders
Inventor: LICHTER JAY
IPC: A61K31/10
Filed: 2005-08-17
Abstract: Described herein are combination methods, compositions and therapies for treating ophthalmic conditions or diseases arising from, associated with or leading to the overproduction of waste products in the visual cycle. Agents included within these combinations are 13-cis-retinyl derivatives; other agents included within these combinations are selected from vitamins, antioxidants, minerals, inducers of nitric oxide production, anti-inflammatory agents, and negatively-charged phospholipids. Such combination methods may be used as single or multiple administration therapies, or in combination with other agents or therapies.