baber/WOPTO huggingface dataset:
Patent WO-2022256824-A1 (WO)
Title: Methods and compositions for treating fibrosis
Inventor: HUBBELL JEFFREY
IPC: C12N15/62
Filed: 2022-06-02
Abstract: Blocking antibodies against αMβ2 (CBP-α-αMβ2), αM (CBP-α-αM), α3 (CBP-α-α3), and anti-TGFβ as well as inhibitors of Talin2 reverse fibrosis in a mouse fibrosis model. Accordingly, aspects of the disclosure relate to inhibitors of Talin2 and inhibitors of the integrins αMβ2, αM, and α3. Aspects relate to a method for treating and/or reversing fibrosis in a subject comprising administering a composition comprising an inhibitor of Talin2 or a composition comprising a nucleic acid of the disclosure. Further aspects relate to a method for treating and/or reversing fibrosis in a subject comprising administering a composition comprising an antibody conjugate of the disclosure or a composition comprising an inhibitor or blocking agent of integrin α3, αM, αMβ2, or combinations thereof to the subject. Methods also include treating kidney fibrosis in a subject comprising administering a composition comprising an anti-TGFβ antibody operatively linked to an ECM-affinity peptide. The methods may be for reducing or decreasing the amount of existing fibrosis. The methods differ from traditional methods for treating fibrosis, since the current methods do not delay or inhibit the progression of fibrosis, but instead have shown to reverse, reduce, and/or decrease existing fibrosis. Accordingly, methods of the disclosure may be used in a manner that provides treatment to existing fibrosis rather than a prophylactic to prevent more fibrosis.
Patent WO-2022261665-A1 (WO)
Title: Dashboard visualization for a portfolio of assets
Inventor: JAYATHIRTHA SRIHARI
IPC: G06Q50/16
Filed: 2022-06-10
Abstract: Various embodiments described herein relate to providing a dashboard visualization for a portfolio of assets. In this regard, a request to obtain asset data for a dashboard visualization associated with a portfolio of assets is transmitted to a server system. The request comprises an asset descriptor and a user identifier. In response to the request, the asset data is received from the server system. The asset data is configured based on the asset descriptor and the user identifier, and the asset data comprising prioritized actions for the portfolio of assets. Furthermore, in response to the request, the dashboard visualization is rendering based on the asset data and via an electronic interface of a user computing device. The dashboard visualization is configured to provide the prioritized actions for the portfolio of assets as respective interactive display elements via the electronic interface.
Patent WO-2023010005-A1 (WO)
Inventor: HUNG RAYMOND
IPC: H01L21/768
Filed: 2022-07-26
Abstract: Methods for reducing interface resistance of semiconductor devices leverage dual work function metal silicide. In some embodiments, a method may comprise selectively depositing a metal silicide layer on an Epi surface and adjusting a metal- to-silicon ratio of the metal silicide layer during deposition to alter a work function of the metal silicide layer based on whether the Epi surface is a P type Epi surface or an N type Epi surface to achieve a Schottky barrier height of less than 0.5 eV. The work function for a P type Epi surface may be adjusted to a value of approximately 5.0 eV and the work function for an N type Epi surface may be adjusted to a value of approximately 3.8 eV. The deposition of the metal silicide layer on the Epi surface may be performed prior to deposition of a contact etch stop layer and an activation anneal.
Patent WO-2023039354-A1 (WO)
Inventor: CHAMPAGNE LLOYD P
IPC: A61B17/72
Filed: 2022-09-02
Abstract: L'invention concerne un système de traitement de fracture pouvant comprendre une paire d'implants posés par embrochage croisé dans le canal médullaire d'un os, guidé par au moins un fil de guidage ayant au moins deux diamètres. Le système permet un dimensionnement plus précis de la longueur d'implants nécessaires pour obtenir un ancrage bicortical pour une stabilité améliorée, ainsi qu'une anti-rotation du site de fracture. Le dimensionnement et le placement plus précis des implants posés par embrochage croisé permettent en outre aux deux extrémités des implants de se loger au-dessous de la surface extérieure de l'os ou de l'affleurer, ce qui peut réduire le risque d'infection. Le fil de guidage peut permettre l'insertion des implants à l'aide d'une technique à canule en vue d'une procédure chirurgicale facilitée et d'un meilleur résultat, les implants ayant une épaisseur de paroi suffisante pour la longueur souhaitée pour obtenir un ancrage bicortical, le diamètre externe de la tige de l'implant étant maintenu de manière à être similaire à un diamètre du fil de guidage.
Patent WO-2023049681-A1 (WO)
Inventor: JIANG RONG
IPC: H03F1/22
Filed: 2022-09-19
Abstract: Methods and devices to support multiple gain states in amplifiers are described. The methods and devices are based on implementing a feedback element in the amplifier and adjusting the impedance of the feedback element to provide a desired gain while maintaining the overall performance of the amplifier and reducing degradation of the S12 parameter. The feedback element includes an adjustable attenuator and a tunable resistive element. The adjustable attenuator is provided in a path that is common to the feedback path and the bypass path of the amplifier. Exemplary implementations of adjustable attenuators are also presented.
Patent WO-2023086717-A1 (WO)
Inventor: MANOLAKOS ALEXANDROS
IPC: G01S5/02
Filed: 2022-10-12
Abstract: Des mesures de positionnement pour déterminer l'emplacement d'un équipement utilisateur (UE) peuvent être obtenues dans une fenêtre temporelle configurée, telle qu'une fenêtre temporelle de mesure ou une fenêtre de traitement de signal de référence de positionnement (PRS). Si une ou plusieurs mesures de position ne peuvent pas être obtenues dans la fenêtre configurée, l'entité de mesure peut fournir un rapport d'erreur à l'entité de positionnement indiquant l'impossibilité d'obtenir une ou plusieurs mesures de positionnement dans la fenêtre temporelle configurée. Le message d'erreur peut être fourni dans le rapport d'informations d'emplacement fourni. Le message d'erreur peut comprendre la synchronisation de l'erreur dans la fenêtre temporelle configurée, par exemple, si l'erreur s'est produite au début ou à la fin de la fenêtre temporelle configurée. Le message d'erreur peut en outre indiquer la cause de l'erreur, telle qu'une défaillance pour recevoir une fenêtre de traitement de PRS, ou que le PRS a une faible priorité par rapport à des signaux ou canaux de liaison descendante.
Patent WO-2023069956-A1 (WO)
Title: Silk stimulated collagen and claudin-1 expression, and silk stimulated anti-inflammatory effects
Inventor: ALTMAN GREGORY
IPC: A61K8/06
Filed: 2022-10-18
Abstract: The disclosure provides silk fibroin compositions for stimulating collagen expression, claudin-1, and-or an anti-inflammatory effect in a subject, and methods of use thereof.
Patent WO-2023133023-A1 (WO)
Title: Support of coverage gaps for satellite access
Inventor: EDGE STEPHEN WILLIAM
IPC: H04B7/185
Filed: 2022-12-13
Abstract: A user equipment (UE) may access a public land mobile network (PLMN) via a communication satellite. The UE may receive satellite coverage data from the serving PLMN via the communication satellite indicating at which locations and/or at which times satellite coverage is available. The UE may determine, based on the satellite coverage data, a first time of satellite unavailability for a location of the UE and a second time of satellite availability. The UE may enter a no coverage state following the first time. The UE may inhibit mobile originating requests and/or reduce a frequency of satellite cell searching while in the no coverage state. The UE may leave the no coverage state at the second time. The satellite coverage data may comprise a coverage map for a grid of locations. Extra coverage data may be provided for satellite availability for other PLMNs and/or for terrestrial cells.
Patent WO-2023141173-A1 (WO)
Inventor: MAUL HOLGER
IPC: B60R21/2338
Filed: 2023-01-18
Abstract: Un composant pour habitacle peut comprendre un airbag et un mécanisme de retenue pour retenir un élément de retenue pour un déploiement d'airbag standard et pour libérer l'élément de retenue pour un déploiement d'airbag étendu. Dans un déploiement standard, l'airbag peut être gonflé sous une forme standard ; dans un déploiement étendu, l'airbag peut être gonflé sous une forme/un aspect étendu. Le composant peut comprendre un agencement d'élément/d'attache à l'intérieur de l'airbag et couplé à l'élément de retenue pour un déploiement standard. L'élément peut comprendre une section destinée à retenir l'airbag pour un déploiement standard, une section destinée à libérer le déploiement étendu et une connexion pour l'élément de retenue. L'élément de retenue peut comprendre une sangle, une corde, une boucle, etc. Le mécanisme de retenue peut comprendre un axe destiné à retenir une ouverture de l'élément de retenue. L'axe ou l'ensemble d'axes peut se rétracter pour libérer l'élément de retenue pour un déploiement d'airbag étendu sous une ou plusieurs formes.
Patent WO-2023219710-A1 (WO)
Title: Déflecteur d'écoulement d'air hypersonique et procédé de fixation
Inventor: ELKINS KEITH A
IPC: B64G1/64
Filed: 2023-03-21
Abstract: Un déflecteur d'écoulement pour un système de véhicule aérien comprend un corps de déflecteur d'écoulement, une attache disposée dans un intérieur du corps de déflecteur d'écoulement, et un ressort à l'intérieur de l'attache. Le corps de déflecteur d'écoulement comprend une première partie au niveau d'une extrémité avant formée pour venir en prise avec une surface d'une carrosserie de véhicule aérien et une seconde partie au niveau d'une extrémité arrière formée pour venir en prise avec une surface d'un moteur de suralimentation. Le corps de déflecteur d'écoulement peut comprendre une pluralité de segments de corps agencés pour former le corps de déflecteur d'écoulement. L'attache peut être configurée pour s'ajuster autour d'une partie d'une bride arrière de la carrosserie de véhicule aérien et venir en prise avec celle-ci. Le ressort peut être précontraint et agencé pour appuyer sur la bride arrière lorsque l'attache vient en prise avec la partie de la bride arrière.
Patent WO-2023183646-A1 (WO)
Title: Adaptive sensors to assess user status for wearable devices
Inventor: ESCUDERO JOHANA GABRIELA COYOC
IPC: G06F1/3203
Filed: 2023-03-27
Abstract: A device is provided, including a frame that supports two eyepieces, a capacitive sensor mounted on the frame, an inertial measurement unit mounted on the frame, and a circuit component inside the frame, wherein the circuit component electrically couples the capacitive sensor and the inertial measurement unit with a processor and a memory inside the frame. A method for using the above device is also provided.
Patent WO-2023220103-A1 (WO)
Inventor: FREDJ NASSER
IPC: A61K31/716
Filed: 2023-05-10
Abstract: This document provides dietary supplement compositions. For example, dietary supplement compositions having beta glucan, quercetin, and one or more of vitamin A, vitamin C, vitamin D, and zinc are provided herein.
Patent WO-2023239519-A1 (WO)
Title: Gestion de configuration de positionnement améliorée dans un état rrc inactif
Inventor: YERRAMALLI SRINIVAS
IPC: G01S5/02
Filed: 2023-05-11
Abstract: Des aspects de la présente invention peuvent améliorer la gestion de configuration de positionnement pour un UE et/ou une entité de positionnement pendant que l'UE est dans un état RRC inactif. Selon un aspect, un UE effectue un ensemble de mesures associées à une pluralité de signaux DL provenant d'une première entité de réseau, l'ensemble de mesures étant effectué pendant un état RRC inactif de l'UE. L'UE transmet, sur la base de l'ensemble de mesures pour la pluralité de signaux DL, une demande de configuration mise à jour pour un ensemble de ressources de positionnement de SRS à la première entité de réseau. L'UE reçoit une indication de la configuration mise à jour pour l'ensemble de ressources de positionnement de SRS sur la base de la demande.
Patent WO-2024006239-A1 (WO)
Inventor: XU XIAOCHUN
IPC: C10G3/00
Filed: 2023-06-27
Abstract: L'invention concerne des systèmes et des procédés pour la production de fractions de composants d'un carburéacteur et/ou d'un mélange de carburéacteurs renouvelables à l'aide d'un système de réaction à un seul étage. Bien qu'un seul étage de séparation soit utilisé, les systèmes et les procédés peuvent réduire ou réduire au minimum le volume d'une charge d'alimentation exposé à des conditions d'hydrocraquage pendant la production continue d'une fraction dans la plage d'ébullition de carburéacteur ayant des propriétés d'écoulement à froid bénéfiques.
Patent WO-2024010900-A1 (WO)
Inventor: HALL III THOMAS A
IPC: H01R24/38
Filed: 2023-07-07
Abstract: An electrical connector includes a connector housing and a core that is inserted into the connector housing. The core includes a shell, a center conductor, a ground conductor, and an insulating spacer provided between the center conductor and the ground conductor. Internal components of the core can be manufactured by an additive manufacturing process.
Patent WO-2023159085-A1 (WO)
Inventor: SCABOO KRISTIAN MICHAEL
IPC: C12Q1/68
Filed: 2023-02-15
Abstract: L'invention concerne un procédé pour séparer et analyser un échantillon liquide, tel qu'un échantillon sanguin. Le procédé peut comprendre les étapes consistant à associer l'échantillon à des réactifs liquides, puis à faire chauffer l'échantillon à une température appropriée pendant une durée suffisante. On peut ensuite faire passer le mélange échantillon-réactifs à travers un filtre. Le liquide obtenu peut ensuite être exposé à la lumière dans une chambre de détection puis détecté par un capteur optique. Les données délivrées par le capteur optique peuvent être présentées sur un afficheur sur le dispositif et/ou transmises sans fil ou en mode filaire à un autre dispositif. L'invention concerne également un dispositif pour mettre en oeuvre ledit procédé.
Patent WO-2023173082-A1 (WO)
Title: Adaptive satellite communications
Inventor: LEE LIN-NAN
IPC: H04B7/185
Filed: 2023-03-10
Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for improving adaptive satellite communication. In some implementations, a method includes receiving, by a receiver and from a transmitter, code blocks transmitted according to a first set of parameters that comprises one or more of a first modulation used to transmit the code blocks or a first coding used to encode the code blocks for transmission. A number of corrupted code blocks and a number of parity blocks in a series of the code blocks received are determined. The number of corrupted code blocks are compared with the number of parity blocks. A second set of parameters are determined based on the comparison of the number of corrupted code blocks with the number of parity blocks. The second set of parameters are communicated to the transmitter for subsequent transmissions.
Patent WO-2024006657-A1 (WO)
Inventor: WU FENG
IPC: B23K11/00
Filed: 2023-06-22
Abstract: A method of joining metal substrates includes providing a first electrode and a second electrode where at least one characteristic of the first electrode is different from the second electrode. The method includes applying a compressive force to at least two overlapping metal substrates using the first electrode and the second electrode. Optionally one of the at least two metal substrates may be cast aluminum. The method includes applying an electric current by ramping up the electric current at a ramp-up rate over a first time period, applying the electric current at a welding level over a second time period after the first time period, and ramping down the electric current at a ramp-down rate over a third time period after the second time period The ramp-down rate is less than the ramp-up rate.
Patent WO-2024020429-A1 (WO)
Title: Immune cell therapy
Inventor: XIONG GUANGYAN
IPC: C07K14/47
Filed: 2023-07-19
Abstract: The present disclosure provides compositions and methods for improving immune cell therapy. In particular aspects, the present disclosure relates to expression construct(s) expressing a chimeric antibody-T cell receptor (TCR) construct (caTCR) and a chimeric stimulating receptor (CSR) that both specifically target glypican 3 (GPC3), along with a human c-Jun polypeptide.
Patent DK-201400395-A1 (DK)
Title: Large slow-running turbocharged two-stroke self-igniting internal combustion engine with a starting air system
Inventor: JENSEN KIM
IPC: F02N9/04
Filed: 2014-07-17
Abstract: A large slow-running turbocharged two-stroke internal combustion engine of the uniflow type with crossheads (41). The engine comprises a plurality of cylinders (1a..1n), and a source of pressurized air (8). Each cylinder (1) is provided with scavenge ports (17) at or near the lower end of the cylinder (1a..1n) a cam controlled exhaust valve (4a..4n) at the top of the cylinder (1a..1n), the exhaust valve (4a..4n) being resiliently urged to its closed position by a pneumatic spring (30), one or more fuel injection valves (6a..6n), and a starting air valve (13a..13n) connected to the source of pressurized air. The engine further comprises a starting air distributor (11) configured for pneumatically and individually activating the starting air valves (13a...13n), and means for overruling an individual activation of a starting air valve (13a...13n) by the starting air distributor (11). The means for overruling being configured to overrule an individual activation of a starting air valve (13a...13n) when the exhaust valve (4) associated with the same cylinder is open.
Patent DK-201500115-A1 (DK)
Title: Clarifier with acid for low ash lactose
Inventor: WAGNER PETER
IPC: C13K5/00
Filed: 2015-02-28
Abstract: A process for the production of low ash levels lactose crystals comprising clarifying a whey permeate after calcium precipitation followed by pH-adjustment to dissolve precipitates of calcium phosphates not removed by clarification.
Patent DK-201770704-A1 (DK)
Title: Centrifugal fan with an internal motor
Inventor: BRZESKI MICHAL
IPC: F23L5/02
Filed: 2017-09-19
Abstract: A centrifugal fan with an internal motor and a one-side inlet of air, having a rotor with a blade-ring, inside of which a drive motor is located, according to the invention the fan has a stub (7) forming an extension of the motor´s shaft, taken out outside the fan housing through a hole (6) in a rear wall (5) opposite to the inlet of air (4).
Patent DK-201970557-A1 (DK)
Title: Oil-in-water emulsion-based sunscreen
Inventor: Shadi Jafarzadeh
IPC: A61K8/72
Filed: 2019-09-06
Abstract: One aspect of the invention relates to an oil-in water sunscreen composition comprising at least one sunscreen agent, at least one solvent, at least one emulsifier, at least one film former and at least one preservative, wherein said emulsifier is present in an amount in the range of 1.00-3.00 %(w/w), and wherein said film former is present in an amount in the range of 1.50-3.50 %(w/w), and wherein said preservative is present in an amount in the range of 0.05-2.50 %(w/w). A second aspect of the present invention relates to the use of at least one emulsifier for increasing the skin feel and improving the texture/emulsion structure of a sunscreen composition of the invention. A third aspect of the present invention relates to the use of at least one film former for increasing the durability and/or water resistance of a sunscreen composition of the invention. A forth aspect of the present invention relates to the use of at least one preservative for increasing the shelf-life of a sunscreen composition of theinvention. A fifth aspect of the invention relates to a process for the manufacture of a sunscreen composition of the invention.
Patent DK-202270605-A1 (DK)
Title: 2-(2-oxo-3-pyrolin-1-yl)acetamides as anticonvulsants
Inventor: LIGA ZVEJNIECE
IPC: C07D207/273
Filed: 2022-12-13
Abstract: This invention relates to the preparation of novel substituted acetamides of formula la-c and their use as anticonvulsants (I) a) R=Ph, R1=Me; b) R=Ph, R1=i-Pr; c) R=EtO, R1=Et.
Patent PH-12015500121-A1 (PH)
Title: Video encoding method and video encoding apparatus and video decoding method and video decoding apparatus for signaling sao parameters
Inventor: ELENA ALSHINA
IPC: H04N21/4385
Filed: 2015-01-20
Abstract: The present invention relates to the signaling of an SAO parameter determined to minimize an error between an original image and a restored image in a video encoding and decoding operation. Disclosed is an SAO decoding method which acquires left SAO aggregation information and upward SAO aggregation information which are entropy-encoded based on a context from the bitstream of the largest coding unit, acquires SAO on/off information which is entropy-encoded based on a context for each color component from the bitstream, acquires offset absolute value information for each SAO category entropy-encoded in a bypass mode, and acquires either the band location information and edge class information which are entropy-encoded in a bypass mode.
Patent PH-12016500480-A1 (PH)
Title: Antibacterial 2h-indazole derivatives
Inventor: JEAN-CHRISTOPHE GAUVIN
IPC: C07D413/10
Filed: 2016-03-11
Abstract: The invention relates to antibacterial compounds of formula (I) wherein R1 is H or halogen; R2 is alkynyloxy or the group M; R3 is H or halogen; M is one of the groups (A, B, C, D) wherein A is a bond, CH2 CH2, CH=CH or C=C and R1A, R2A, R3A, R1B and R1C are as defined in claim 1; and salts thereof.
Patent PH-12016501150-A1 (PH)
Title: Pre-moistened wipes for use in treating anal-rectal irritations and disorders
Inventor: ROBERT AGISIM GARY
IPC: A61K8/86
Filed: 2016-06-14
Abstract: Many people who suffer from anal rectal discomfort and disorders need fibrous sheet materials which are pre-moistened with a solution for improved cleansing without excessive skin irritation. The invention particularly concerns wet wipes, such as anal- rectal wipes, which comprises a solution comprising hamamelis water or witch hazel, to effectively treat anal-rectal disorders.
Patent PH-12016501517-A1 (PH)
Title: Tetrazolone-substituted dihydropyridinone mgat2 inhibitors
Inventor: AHMAD SALEEM
IPC: C07D401/04
Filed: 2016-08-01
Abstract: The present invention provides compounds of Formula (I): a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, a solvate thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.
Patent PH-12016502185-A1 (PH)
Title: Apparatus and method for synchronous multiplexing and multiple access for different latency targets utilizing thin control
Inventor: TINGFANG JI
IPC: H04W72/12
Filed: 2016-11-03
Abstract: Aspects of the disclosure provide for a thin control channel structure that can be utilized to enable multiplexing of two or more data transmission formats. For example, a thin control channel may carry information that enables ongoing transmissions utilizing a first, relatively long transmission time interval (TTI) to be punctured, and during the punctured portion of the long TTI, a transmission utilizing a second, relatively short TTI may be inserted. This puncturing is enabled by virtue of a thin channel structure wherein a control channel can carry scheduling information, grants, etc., informing receiving devices of the puncturing that is occurring or will occur. Furthermore, the thin control channel can be utilized to carry other control information, not being limited to puncturing information. Other aspects, embodiments, and features are also claimed and described.