baber/WOPTO huggingface dataset:
Patent EP-3958836-A1 (EP)
Inventor: ALPHANDÉRY EDOUARD
IPC: A61K33/26
Filed: 2020-04-23
Abstract: The present invention relates to a method for increasing the release of at least one compound, said compound being initially an initial compound bound to at least one initial nanoparticle, said initial compound bound to said initial nanoparticle forming an initial particle, wherein the initial particle comprises at least one active ingredient, said method comprising at least one step of alteration of the initial particle and at least one step of physico-chemical disturbance of an altered particle resulting from the alteration.
Patent EP-3980480-A1 (EP)
Inventor: Hofmann Jörg
IPC: C08G65/26
Filed: 2020-05-29
Abstract: Die Erfindung betrifft ein Verfahren zur Herstellung eines Polyoxyalkylenpolyols umfassend die Anlagerung eines Alkylenoxids an eine H-funktionelle Startersubstanz in Gegenwart eines Doppelmetallcyanid (DMC)-Katalysators, wobei das Alkylenoxid mit dem Massenstrom  m(Alkylenoxid) , die H-funktionelle Startersubstanz mit dem Massenstrom  m(Startersubsanz)  und der Doppelmetallcyanid (DMC)-Katalysator in einem Dispersionsmittel mit dem Massenstrom  m(DMC)  während der Reaktion kontinuierlich in den Reaktor mit dem Reaktionsvolumen V dosiert werden und das resultierende Reaktionsgemisch kontinuierlich aus dem Reaktor entfernt wird, und wobei der Quotient der Summe der Massenströme ∑ m  aus  m(Alkylenoxid) ,  m(Startersubsanz)  und  m(DMC)  zu dem Reaktionsvolumen V im stationären Zustand größer oder gleich 1200 g/(h·L) ist.
Patent EP-3983870-A1 (EP)
Title: Digital mission preparation system
Inventor: LEBEAUPIN FRANÇOIS
IPC: A63F13/60
Filed: 2020-06-10
Abstract: An aspect of the invention relates to a system for mission preparation on the basis of digital mapping, comprising a mission editor which generates mission elements which vary during a plurality of predetermined time phases, comprising, in a network:
- a mission server, - a mapping server, - a server for sharing at least one centre of the map and - a plurality of augmented reality headsets, at least one of the augmented reality headsets, referred to as the master headset, being able to generate at least one instruction to modify the centre, each headset being able to receive at least two sets of elevation and terrain tiles from the mapping server, the mission server interfacing with the headsets in order to share and update the mission elements and to make them vary over time.
Patent EP-3977190-A1 (EP)
Inventor: DANNOUX THIERRY LUC ALAIN
IPC: G02B6/38
Filed: 2020-05-20
Abstract: Devices such as multiports comprising connection ports with associated sliding actuators that engage securing members and methods for making the same are disclosed. In one embodiment, the device comprises a shell, at least one connection port, and at least one sliding actuator that engages with a complementary securing member. The at least one connection port is disposed on the multiport with the at least one connection port comprising an optical connector opening extending from an outer surface of the multiport to a cavity of the multiport and defining a connection port passageway. The at least one securing member is associated with the connection port passageway, and is capable of translating in a direction that is transverse to the longitudinal axis of the connection port passageway. T ranslating the sliding actuator in a longitudinal direction transverse to the translation direction of the securing member allows the release of an optical connector disposed in the connection port.
Patent EP-3976623-A1 (EP)
Title: Composés ciblant des protéines et leurs compositions pharmaceutiques, et leurs applications thérapeutiques
Inventor: CHAN KYLE W H
IPC: A61P25/28
Filed: 2020-05-22
Abstract: La présente invention concerne des composés, par exemple, un composé de formule (I), qui modulent une fonction protéique et/ou restituent l'homéostasie des protéines. L'invention concerne également un procédé de modulation d'une maladie, d'un trouble, d'un état ou d'une réponse à médiation par des protéines. L'invention concerne en outre des compositions, et ces compositions en combinaison avec d'autres agents thérapeutiques.
Patent EP-3986329-A1 (EP)
Inventor: LAZZARO RICHARD
IPC: A61F2/04
Filed: 2020-06-18
Abstract: An airway support device of the present disclosure can be attached to tracheal and/or bronchial cartilage on opposing sides of a tracheal and/or bronchial wall to pull the tracheal and/or bronchial cartilages toward each other to reconstruct and/or reshape to a normal anatomy across the membranous tracheal and/or bronchial wall and thus relieving tension across the tracheal and/or bronchial wall. The airway support device can include at least two longitudinal strips that extend longitudinally along and are attached (e.g,, sutured) to the trachea and/or bronchus on opposite sides of the tracheal and/or bronchial wall. Pairs of lateral strips extending from each of the longitudinal strips can be attached to each other under tension. The tracheal and/or bronchial wall can be attached (e.g., sutured) to the lateral strips to open the airway of the trachea and/or bronchus.
Patent EP-3999080-A1 (EP)
Title: P21 expressing monocytes for cancer cell therapy
Inventor: PERFETTINI JEAN-LUC
IPC: A61K35/15
Filed: 2020-07-17
Abstract: Identification of effective targets alleviating the programmed cell removal (PrCR) of tumor cells by macrophages is of very high interest. The present inventors have identified that the cyclin-dependent kinase inhibitor p21 protein is a strong regulator of the macrophage-mediated PrCR. Also, they showed that the adoptive transfer of p21 overexpressing monocytes induces macrophage PrCR and transition from an anti-inflammatory to a pro-inflammatory phenotype  in vivo , delays cancer progression and increases significantly the overall survival of mice engrafted with cancer cells. The present invention therefore concerns therapeutic compositions comprising monocytes that over-express the cyclin-dependent kinase inhibitor p21 protein, and their use for treating mammals suffering from cancer, especially leukemia.
Patent EP-4013219-A1 (EP)
Title: A method and arrangement for barn cleaning
Inventor: BRINK MAREK
IPC: A01K1/01
Filed: 2020-07-24
Abstract: A method, control unit, computer program and arrangement for barn cleaning are provided. The method comprises obtaining of information from one or more cameras mounted such as to capture images of an area of operation of an automatic barn cleaning device and identifying of at least one location in said area of operation being subjected to manure, based on the obtained information. The method further comprises calculating of a route for the automatic barn cleaning device based on the identified at least one location, and controlling of the automatic barn cleaning device based on the calculated route.
Patent EP-4005025-A1 (EP)
Inventor: NOSRATI MEHRDAD
IPC: H01Q21/00
Filed: 2020-07-18
Abstract: Apparatuses, methods, and systems for an antenna element are disclosed. For an embodiment, the antenna element includes a feed line layer, a first substrate adjacent to the feed line layer, a ground layer adjacent to the first substrate, a second substrate adjacent to the ground layer, and a third layer adjacent to the second substrate. The feed line layer includes a conductive fork-shape that includes a conductive handle adapted to be electrically connected to a center conductor of a coaxial line, a conductive cross-section that crosses an end portion of the conductive handle, and a plurality of conductive fingers. For an embodiment, a rectangular slot is formed in the ground layer, wherein a length of the rectangular slot is perpendicular to the conductive handle. For an embodiment, the third layer includes four parasitic elements, wherein each parasitic element is electrically connected to the ground layer through a shorting via.
Patent EP-3924479-A1 (EP)
Inventor: GAUDELLI NICOLE
IPC: C12N9/22
Filed: 2020-02-13
Abstract: The disclosure provides compositions comprising novel adenosine base editors (e.g., ABE8) that have increased efficiency and methods of using these adenosine deaminase variants for editing a target sequence.
Patent EP-3926188-A1 (EP)
Inventor: OU Iwa
IPC: F16C33/74
Filed: 2020-02-12
Abstract: There is provided a pair of sliding components capable of suppressing contamination from being accumulated in a shallow groove of a dynamic pressure generation mechanism. A pair of sliding components 10, 12 formed in an annular shape and disposed at a relatively rotating position of a rotary machine. The sliding components is constituted by a first sliding component 10 and a second sliding component 12. A sliding surface 11 of the first sliding component 10 is provided with a plurality of dynamic pressure generation mechanisms 14 each of which includes at least a shallow groove communicating with a leakage side. A sliding surface 21 of the second sliding component 20 is provided with deep grooves 22 each of which has a dimension deeper than that of the shallow groove of each of the dynamic pressure generation mechanisms 14 and communicates with the leakage side, each of the deep grooves 22 overlapping with the shallow groove each of the dynamic pressure generation mechanisms 14 during relative rotation of the first and second sliding components 10, 20.
Patent EP-4017890-A1 (EP)
Title: Coating material system comprising a mercapto group-containing compound
Inventor: HOFFMANN PETER
IPC: C08G18/22
Filed: 2020-08-18
Abstract: The invention relates to a coating material system which comprises components (A) to (C) and (K) and also, optionally, further components, with, in a first option, all components (A) to (C) and (K) and also, where present, the further optional components being present separately from one another, in other words the individual components not being mixed with one another. In a second option of the coating material system of the invention, conversely, the aforementioned components may also be mixed wholly or at least partly with one another. Where the components are at least partly mixed with one another, this means that, for example, component (C) is mixed with component (A), while component (B) is present separately from this mixture of (A) and (C). Optionally, however, component (B) may also be mixed with a portion of component (C). Furthermore, the mixtures of (A) and (C) and of (B) and (C) may additionally comprise at least one optional component such as a solvent, for example. Component (A) comprises at least one polyhydroxy group-containing compound, wherein the polyhydroxy group-containing compound of component (A) has an acid number of between 0 and 30 mg KOH/g, and component (B) comprises at least one polyisocyanate-containing compound. Component (C), by contrast, is a catalyst comprising bismuth (Bi) as metal component and at least one further metal component such as lithium (Li). Component (K) is at least one mercapto group-containing compound. Further components which may be present in the coating material system of the invention include, for example, hydroxyl-containing compounds (D), coating additives (F), pigments (H) and/or solvents (J).
Patent EP-4017984-A1 (EP)
Title: Lentiviral transduction methods
Inventor: SILK JONATHAN
IPC: C12N15/87
Filed: 2020-08-20
Abstract: This invention relates to methods of transducing mammalian cells that comprise exposing a population of mammalian cells to a poloxamer in the absence of a lentiviral vector for 6 hours or more to produce a transduction-primed mammalian cell population, exposing the transduction-primed mammalian cell population to a lentiviral vector, such that the T cells are transduced with the lentiviral vector; and then separating the transduced mammalian cells from the poloxamer. Suitable lentiviral vectors may comprise heterologous nucleic acid that encodes an antigen receptor, such as a T Cell Receptor (TCR) or chimeric antigen receptor. This may be useful, for example, in the transduction of T cells or progenitor cells that differentiate into T cells.
Patent EP-4018595-A1 (EP)
Inventor: KNUDSEN LARS RAMKILDE
IPC: H04L9/08
Filed: 2020-09-11
Abstract: L'invention concerne des dispositifs et des procédés de communication de données entre un premier dispositif électronique et un second dispositif électronique. Les procédés décrits comprennent éventuellement l'obtention, au niveau du premier dispositif électronique, d'une clé de base ayant une longueur de N bits ; la détermination, au niveau du premier dispositif électronique, d'une première clé mise à jour basée sur la clé de base, dans laquelle la première clé mise à jour a une longueur d'au moins N+M bits, M est supérieur à 4, et dans laquelle la détermination de la première clé mise à jour comprend l'exécution d'une opération cryptographique, telle qu'une fonction de hachage, au moins 2M fois ; et le cryptage, au niveau du premier dispositif électronique, des données avec la première clé mise à jour pour la fourniture de données chiffrées.
Patent EP-4045792-A1 (EP)
Inventor: ZHAO CHUNYANG
IPC: H02J3/32
Filed: 2020-09-14
Abstract: Selon des modes de réalisation décrits dans la présente invention, la commande du système d'alimentation auxiliaire dans une centrale électrique hybride (310) est fournie par la détermination d'un seuil de tirage de grille à partir d'une grille d'alimentation externe (320); la surveillance de la consommation d'énergie pour des systèmes alimentés (312, 313) de la centrale électrique hybride (310); la surveillance de la production d'énergie de la centrale électrique hybride (310); la décharge d'une source d'alimentation alternative d'un ou de plusieurs éléments parmi un système de stockage d'énergie, ESS, (314) et un générateur auxiliaire (315) en réponse à la consommation d'énergie dépassant le seuil de tirage de grille; et la mise en œuvre d'algorithmes de prédiction pour la production d'énergie de la centrale électrique hybride (310) et la consommation d'énergie. En conséquence, une source d'énergie est gérée entre plusieurs sources alternatives (314, 315) et la grille d'alimentation externe (320) pour satisfaire des critères définis par l'opérateur de la centrale lors du maintien de la puissance dans diverses conditions de vitesse du vent.
Patent EP-4038451-A1 (EP)
Inventor: MANCA MICHELE ANDREA
IPC: G02F1/163
Filed: 2020-09-25
Abstract: It relates to a thermo-responsive dual band electrochromic device, which is capable of selectively controlling the amount of sunlight radiation transmitted in the visible and in the near- infrared regions by operating under four distinct optical regimes, namely: fully transparent, visible blocking, near-infrared blocking, and fully blocking. The device can be regulated either by an electric stimulus, namely by controlling the sign and the intensity of the applied bias voltage, or by a thermal stimulus. In the latter the attenuation of incoming thermal radiation results increased as temperature increases. The thermo-responsive dual band electrochromic device comprises a first electrode consisting of a first transparent conductive substrate topped by a first electro- optically active layer and a second electrode consisting of a second transparent conductive substrate topped by a second electro-optical ly active layer separated by a temperature-dependent ion conductive layer consisting of a thermo-responsive polymer gel, an ion conductor and a plasticizer.
Patent EP-4034152-A1 (EP)
Inventor: WANG WENXIN
IPC: C12N15/88
Filed: 2020-09-22
Abstract: A nanoparticulate composition comprises a gene editing ribonucleoprotein system complexed within a cationic polymer. The cationic polymer may be a Poly-beta amino ester hyperbranched polymer, especially a 4-branching hyperbranched polymer. The gene editing ribonucleoprotein system may be a CRISPR-Cas9 gene editing system configured to excise a mutation or exon in a gene, replace a mutation in a gene, or produce a knock-down or knock-out of a gene, and in particular configured to excise exon 80 of the COL7A1 gene which codes for the collagen VII protein. Data shows that using
Patent EP-3955853-A1 (EP)
Inventor: HALAK MOSHE
IPC: A61M29/00
Filed: 2020-04-16
Abstract: Apparatus and methods are described for capturing emboli during a medical procedure that is performed at a first location within a subject's body. An intravascular device (24) is configured to perform the medical procedure at the first location. An inner sheath (32) facilitates insertion of the intravascular device (24) into the subject's body, by the intravascular device being inserted via a lumen (31) of the inner sheath (32). A filter (34) extending from a distal-most portion (42) of the inner sheath (32) has a non-radially-constrained configuration in which the filter (34) is configured to prevent at least some emboli that are generated by the medical procedure from passing through the filter (34). Other applications are also described.
Patent EP-4041539-A1 (EP)
Title: Dispositif et procede de formage de conteneur par pliage
Inventor: CIRETTE DAMIEN
IPC: B31B50/58
Filed: 2020-10-09
Abstract: La présente invention concerne le formage de conteneur par pliage de plaque cartonnée avec au moins un couvercle et notamment une languette, au travers d'un dispositif (2) de formage comprenant au moins un convoyeur (3) entraînant ladite plaque (100) cartonnée selon une direction de déplacement; des moyens (5) de rabattage dudit couvercle (104); lesdits moyens (5) de rabattage comprenant au moins une surface (50) d'appui avec ledit couvercle (104), ladite surface (50) d'appui étant actionnée selon un mouvement depuis une position initiale vers une position déployée en rabattage dudit couvercle (104), et inversement; caractérisé par le fait que ladite surface (50) d'appui est mobile selon ladite direction de déplacement, ladite surface (50) d'appui comprenant au moins une courroie (500) sans fin motorisée selon ladite direction de déplacement.
Patent EP-4041699-A1 (EP)
Inventor: ARKOUN MUSTAPHA
IPC: C05D9/02
Filed: 2020-10-06
Abstract: The present invention relates to an aluminosilicate glass for providing a plant with silicon in an assimilable form, a method for treating a plant using this glass and a new powder of said glass. According to the invention, this aluminosilicate glass comprises the following constituents, in a weight content that varies within the limits defined below: SiO2 30-60% Al2O3 10-26% CaO+MgO+Na2O+K2O 15-45%. The invention notably finds applications in the agriculture field.
Patent EP-4045445-A1 (EP)
Inventor: MONTEROSSO ANTONIO
IPC: G01B11/30
Filed: 2020-10-08
Abstract: Method and apparatus (99) for dosing a continuous elongated element (900), for advancing the continuous elongated element (900) along a first tract (110) with an advancement direction (100) for feeding the continuous elongated element (900) to a feeding point (A) with a feeding speed; for optically detecting in continuous at a detection point (R) along the first tract (110) geometrical information relating to a section (200) of the continuous elongated element (900) on a plane perpendicular to the advancement direction (100); for calculating in continuous a value representative of an areal extension of the section (200) as a function of the geometrical information; and for adjusting in continuous the feeding speed as a function of the value representative of the areal extension and of a reference value of feeding flow rate of the continuous elongated element (900) in the feeding point (A).
Patent EP-4054341-A1 (EP)
Title: Carbon dioxide generation
Inventor: DELCOUR JAN
IPC: A21D10/00
Filed: 2020-11-09
Abstract: The invention relates to methods of leavening a batter or dough of a bakery product comprising the steps of : providing a batter or dough comprising an isolated glutamate decarboxylase enzyme or an isolated aspartate decarboxylase enzyme and respectively glutamic acid or a salt thereof or aspartic acid or a salt thereof in a concentration of at least 0.005 mole glutamic acid /kg dough or batter, wherein the batter or dough does not contain added yeast or sourdough bacteria.
Patent EP-4045190-A1 (EP)
Inventor: LEROY FRANCK
IPC: B02C23/12
Filed: 2020-10-14
Abstract: L'invention concerne un procédé de séparation aéraulique en continu de matériaux particulaires constitués d'un mélange de particules hétérogène à la fois en granulométrie et en densité, caractérisé en ce qu'il comprend les étapes de broyage des particules de matériaux, de génération d'un flux de gaz acheminant les particules broyées, de première séparation aéraulique sur ledit flux de gaz pour séparer les particules qu'il contient en une première fraction constituée de particules les plus grossières avec des densités variables et une deuxième fraction constituée de particules les plus fines, de deuxième séparation aéraulique sur ladite première fraction pour séparer les particules qu'elle contient en une troisième fraction constituée de particules les plus grossières et/ou les plus denses et une quatrième fraction constituée de particules les moins grossières et/ou les moins denses, de réinjection de troisième fraction ou de la quatrième fraction à l'entrée du broyage, et de récupération simultanée de la deuxième fraction ainsi que de la quatrième fraction ou de la troisième fraction, respectivement, comme produits de sortie.
Patent EP-4051108-A1 (EP)
Inventor: BURKHOLZ JONATHAN KARL
IPC: A61B5/15
Filed: 2020-10-22
Abstract: A catheter system may include a catheter adapter, a catheter extending distally from the distal end of the catheter adapter, and a needle hub coupled to the catheter adapter. The needle hub may be transparent, and a needle may be secured within the needle hub. The catheter system may also include a flow control plug coupled to the proximal end of the needle hub. In some embodiments, a flashback pathway may be disposed between an outer surface of the flow control plug and an inner surface of the needle hub. In some embodiments, the catheter system may include an inner barrel and an outer barrel, and the inner barrel and the needle hub may be configured to move proximally within the outer barrel to retract the needle. The flashback pathway may be disposed between an outer surface of the needle hub and an inner surface of the inner barrel.
Patent EP-3969035-A1 (EP)
Inventor: WINSTON WILLIAM
IPC: C12N15/26
Filed: 2020-05-14
Abstract: Provided herein are separation moieties that are suitable for use in conjunction with a variety of therapeutic payloads. The separation moieties serve to generate conditionally active macromolecules whereby the macromolecules have reduced or minimal biological activity until the separation moieties are modified under specific conditions.
Patent EP-3974026-A1 (EP)
Inventor: TAKAGI YOUHEI
IPC: A23K20/111
Filed: 2020-05-19
Abstract: Provided is a composition for improving liver function that utilizes a plant-derived resorcinolic lipid, being useful, for example, in improving symptoms of non-alcoholic hepatitis.A plant-derived resorcinolic lipid is used as an active ingredient of the composition for improving liver function. The resorcinolic lipid is preferably an alkylresorcinol and is also preferably derived from a gramineae plant, also preferably from wheat and/or rye bran and/or whole grains. This composition for improving liver function is especially suitably used to improve symptoms of non-alcoholic hepatitis.