Patent SG-11201403106S-A (SG)
Title: Anti-phf-tau antibodies and their uses
Inventor: ALDERFER CHRISTOPHER
IPC: A61K39/00
Filed: 2012-12-19
Abstract: (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 27 June 2013 (27.06.2013) WIPOIPCT (10) International Publication Number WO 2013/096380 A3 (51) International Patent Classification: C07K16/00 (2006.01) A61K39/00 (2006.01) (21) International Application Number: PCT/US2012/070486 19 December 2012 (19.12.2012) (22) International Filing Date: 1 (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 61/577,817 20 December 2011 (20.12.2011) US (71) Applicant: JANSSEN BIOTECH, INC. [US/US]; 800/850 Ridgeview Drive, Horsham, Pennsylvania 19044 (US). (72) Inventors: ALDERFER, Christopher; 145 King of Prus­ sia Road, Radnor, Pennsylvania 19087 (US). JANECKI, Dariusz; 145 King of Prussia Road, Radnor, Pennsylvania 19087 (US). LU, Xuesong; 145 King of Prussia Road, — Radnor, Pennsylvania 19087 (US). MURDOCK, Melissa; 145 King of Prussia Road, Radnor, Pennsylvania 19087 (US). WU, Sheng-Jiun; 145 King of Prussia Road, Rad­ nor, Pennsylvania 19087 (US). MERCKEN, Marc; Turnhoutseweg 30, B-2340 Beerse (BE). VANDER- MEEREN, Marc; Turnhoutseweg 30, B-2340 Beerse (BE). (74) Agents: JOHNSON, Philip S. et al.; Johnson & Johnson, One Johnson & Johnson Plaza, New Brunswick, New Jer­ sey 08933 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — as to the identity of the inventor (Rule 4.17(i)) as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(H)) — as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) — with sequence listing part of description (Rule 5.2(a)) (88) Date of publication of the international search report: 22 August 2013 o 00 m o\ © en i-H o CJ 0 (54) Title: ANTI-PHF-TAU ANTIBODIES AND THEIR USES ^ (57) Abstract: Anti-PHF-tau antibodies and methods of and making using them are disclosed.