baber/WOPTO huggingface dataset:
Patent AT-E292622-T1 (AT)
Inventor: BURNS CHRISTOPHER
IPC: C07D317/68
Filed: 1998-01-21
Granted: 2005-04-15
Abstract: This invention relates to compounds of general formula (I) :   
wherein 
R 1  and R 3  may be the same or different and each independently represents a group -L 1 -R 5  [where L 1  is a direct bond, a straight or branched C 1-6 alkylene chain, a straight or branched C 2-6 alkenylene chain, a straight or branched C 2-6 alkynylene chain or a straight or branched C 1-6 alkylene chain containing an oxygen or sulfur atom, a phenylene, imino (-NH-) or alkylimino linkage, or a sulfinyl or sulfonyl group, in which each of the alkylene, alkenylene and alkynylene chains may be optionally substituted, the substituents chosen from alkoxy, aryl, carboxy, cyano, cycloalkyl, halogen, heteroaryl, hydroxyl, or oxo; and R 5  represents hydrogen, aryl, aroyl, carboxy or an acid bioisostere, cyano, cycloalkyl, cycloalkenyl, heterocycloalkyl, heteroaryl, arylalkoxycarbonyl, -NH-C(=O)-NH 2 , -C=N-O-C(=O)-NH 2 , -C(=O)-NY 1 Y 2 , -NY 1 SO 2 aryl, -NHR 6 , -SR 6 , or -OR 6 ]; 
R 2  and R 4  may be the same or different and are each independently hydrogen or alkyl; or 
R 2  and R 4  together form a bond; or R 1  and R 2 , or R 1  and R 3 , or R 3  and R 4  together with the carbon atom(s) to which they are attached form a 3 to 8 membered cycloalkyl or cycloalkenyl ring, optionally substituted by alkyl, arylalkyl, or heteroarylalkyl, and which may optionally contain a heteroatom selected from O, S or NR 6 ; or R 1  and R 3  together with the carbon atoms to which they are attached form a heteroaryl ring; 
Y represents tetrazolyl, 3,5-dioxo-1,2,4-oxadiazolidinyl, 3-hydroxyisoxazolyl or 3-hydroxy-1-methylpyrazolyl; 
A 1  represents a direct bond, a straight or branched C 1-4 alkylene chain or a NR 6  group; 
Ar is a group chosen from :   
and   
and 
n is 0, 1 or 2; 
and N-oxides thereof, and their prodrugs, pharmaceutically acceptable salts, and solvates (e.g. hydrates), thereof.  Such compounds inhibit the production or physiological effects of TNF and inhibit cyclic AMP phosphodiesterase. The invention is also directed to pharmaceutical compositions comprising compounds of formula (I), their pharmaceutical use and methods for their preparation.
Patent AT-E236606-T1 (AT)
Inventor: YLAENEN HEIMO
IPC: A61C8/00
Filed: 1998-04-15
Granted: 2003-04-15
Abstract: A porous composite suitable for filling a recess or a through-passing hole in an implant. The composite includes particles A prepared from a bioactive material and particles B prepared from a non-bioactive material or weakly bioactive material, which is sintratable with the bioactive material, such that particles A and particles B have been sintered together to a porous composite. Particles A and particles B are essentially homogeneous in size. Also disclosed is an implant which contains a core and the composite.
Patent AT-E349470-T1 (AT)
Inventor: BACA MANUEL
IPC: C12N15/09
Filed: 1998-04-03
Granted: 2007-01-15
Abstract: Humanized and variant anti-VEGF antibodies and various uses therefore are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells  in vitro,  and inhobit tumor growth  in vitro.
Patent AT-E277645-T1 (AT)
Inventor: KESSLER HORST
IPC: A61F2/02
Filed: 1998-05-09
Granted: 2004-10-15
Abstract: The invention describes the possibility of the biofunctionalization of biomaterials, in particular implants, by their made-to-measure coating with synthesized cell- or tissue-selective RGD peptides which in vitro stimulate the adhesion of mainly those cell species which in each case are intended to accomplish the tissue integration of the appropriate biomaterial.
Patent AT-E380881-T1 (AT)
Inventor: NILSEN INGE
IPC: C12N15/09
Filed: 1998-08-06
Granted: 2007-12-15
Abstract: The present invention provides a method of removing nucleic acid contamination in an amplification reaction which comprises use of a thermolabile DNase and a method of preventing or reducing false positive results due to carry-over in a nucleic acid amplification reaction, said method comprising using a thermolabile DNase to degrade carried-over non-target double-stranded DNA present in the amplification reaction mixture. A thermolabile DNase from the shrimp Pandalus borealis has been identified which is suitable for use in the methods of the invention.
Patent AT-E252731-T1 (AT)
Inventor: ZHAO GUOHENG
IPC: G01B11/30
Filed: 1998-07-28
Granted: 2003-11-15
Abstract: A cylindrical mirror or lens is used to focus an input collimated beam of light onto a line on the surface to be inspected, where the line is substantially in the plane of incidence of the focused beam. An image of the beam is projected onto an array of charge-coupled devices parallel to the line for detecting anomalies and/or features of the surface, where the array is outside the plane of incidence of the focused beam.
Patent AT-E240545-T1 (AT)
Inventor: ROGERS MICHAEL D
IPC: A63F13/06
Filed: 1998-09-24
Granted: 2003-05-15
Abstract: A pointing device comprises a substrate with an electrically conductive surface (36) and a resilient return member (12). The return member resiliently supports a resistive surface (20) to contact the electrically conductive surface (36) in a pressed mode when a force (23) is applied to push and deform the return member against the electrically conductive surface. The return member (12) is made of a resistive rubber material. The resistive surface (20) has a voltage variance and is curved to be rocked on the electrically conductive surface (36) in the pressed mode. The voltage variance is detected on the electrically conductive (20) surface and a variable signal is generated and processed. In a specific embodiment, a dome switch is disposed between the resistive surface and the electrically conductive surface to provide a drag function.
Patent AT-E296914-T1 (AT)
Inventor: ZINKEN JOHANNES MATHIAS GERARD
IPC: D06J1/10
Filed: 1998-11-25
Granted: 2005-06-15
Abstract: The invention relates to a method for forming a pleated textile product, comprising the steps of feeding a length of flat material, arranging in the length of material in longitudinal direction thereof a number of pleats which become gradually sharper in the feed direction, and fixing the pleats by heating and/or pressing. The length of material can herein be finished after applying and fixing of the pleats, for instance be cut into pieces in transverse direction. A longitudinal edge of the length of material can also be cut off. The invention further relates to a system for performing this method, with a feeding device, a pleating device and a fixing device. The pleating device can herein comprise a mould with a profiled opening corresponding with the desired contour of the pleated product, while the fixing device can comprise a heated roller with a relatively large diameter. The system can further display a device for finishing the length of material with the fixed pleat(s) which is provided with cutting means.
Patent AT-E256632-T1 (AT)
Inventor: CLUESSERATH LUDWIG
IPC: B67C3/06
Filed: 1999-03-12
Granted: 2004-01-15
Abstract: The interior of the container (6) being filled is temporarily pre-tensioned before the filling stage with a pressurized inert gas, such as carbon dioxide. During the filling stage, the gas displaced from the container as a result of the liquid poured in, is contained under pressure in a return gas collector chamber (23). After filling, the container is returned to atmospheric pressure via a release duct. The housing (7) of the filler element (3) contains a fluid duct (11) which opens into a filler pipe (10) protruding beyond the underside of the filler element. A valve (13) inside the duct opens when the container's aperture (5) is placed tightly against the filler element. A gas duct (14) with opening (15) joins the container's interior. Three separately controlled valves (16,17,18) control the gas-ducts in the housing. Two return valves (25,28) are positioned in two gas ducts. An Independent claim is included for a filler element.
Patent AT-E389062-T1 (AT)
Inventor: FISCHER SIEGFRIED
IPC: D21H19/82
Filed: 1999-10-30
Granted: 2008-03-15
Abstract: A band of paper is coated on the front by liquid resin and fine abrasive, especially corundum, and is then hardened, all in accordance with known principles. In the new process a further coating of resin, free of particles, is applied to the front and hardened.  An Independent claim is included for a plant carrying out the process. This includes the stations: impregnation, single-sided coating, drying (5), coating (6) and final drying (8). Preferred features: In the second coating, preferably 10-80 g/m<2> of resin is applied. The back is coated, preferably with the same weight of resin. During initial coating, the band has a residual moisture of 8-17%. Final drying reduces this to 4-9%. The plant also includes patterned rollers (21, 24) and a further coating section (7). A further variant of the plant, based on the foregoing principles, is described.
Patent AT-E284879-T1 (AT)
Inventor: KRUSHINSKI JOSEPH HERMAN JR
IPC: C07D401/04
Filed: 1999-07-26
Granted: 2005-01-15
Abstract: The present invention relates to a compound of formula <CHEM> or a pharmaceutical acid addition salt thereof; which are useful for activating 5-HT1F receptors and inhibiting neuronal protein extravasation in a mammal.
Patent AT-E267833-T1 (AT)
Inventor: EGLIN DAVID
IPC: B01J31/02
Filed: 1999-12-01
Granted: 2004-06-15
Abstract: Siloxanes are polymerised by equilibration, condensation and/or ring-opening polymerisation using a phosphazene base catalyst. A linear phosphazene base catalyst of the general formula <CHEM> wherein R denotes a C1-10 hydrocarbon or wherein two R groups on one N atom form with the N atom a heterocyclic group, X denotes an anion and n is from 1 to 10 is prepared by reacting a linear phosphonitrile halide compound with a secondary amine or a salt of a secondary amine or a metal amide thereof to form an aminated phosphazene material, followed by an ion exchange reaction replacing the anion with a nucleophile.
Patent AT-E256992-T1 (AT)
Inventor: SASADY NIELS-CHR
IPC: A61B8/08
Filed: 1999-01-05
Granted: 2004-01-15
Abstract: An apparatus for insertion into the human body and which comprises one or more optionally scanning transducers 17,18 and a needle guide 12, which can be operated from the outside. The needle guide 12 is used for collecting tissue samples from the human body. According to the invention the needle guide 12 is separate from the other part of the apparatus which for hygienic reasons is covered by a sterile sheath 14. The needle guide 12 is thus attached to the other part of the catheter via the sheath. In other words the needle guide 12 is arranged outside the sheath 14 in such a manner that the needle need not penetrate the sterile sheath 14, which otherwise would entail that the apparatus should be disinfected after use.
Patent AT-E226016-T1 (AT)
Inventor: DOLLINGER MARKUS
IPC: A01N43/653
Filed: 1999-01-12
Granted: 2002-11-15
Abstract: The invention relates to novel herbicidal synergistic active compound combinations comprising on the one hand known N-aryl-triazoline(thi)ones and on the other hand known N-arylsulphonylamino(thio)carbonyl-triazoline(thi)ones which can be used particularly successfully for the selective control of weeds in various crops of useful plants.
Patent AT-E297157-T1 (AT)
Inventor: VOSS GREGORY I
IPC: A61B5/022
Filed: 1999-07-15
Granted: 2005-06-15
Abstract: Apparatus is disclosed for non-invasively monitoring a subject's blood pressure, in which a pressure sensor assembly (14) that includes a pressure transducer (50) is compressed against tissue overlying an artery, with sufficient force to compress the artery. A motor (32) first servo control system optimizes the amount of artery compression, which occurs at a mean transmural pressure of about zero, by modulating one side of a lever arm (36) compressing the assembly against the tissue, creating a pressure signal indicative of transmural pressure. Since different pressure effects are realized according to the amount of artery compression, an appropriate control signal can be produced that provides for a second motor (34) to adjust the other side of the lever arm (36) to provide the optimum compression of the assembly into the tissue overlying the artery. The apparatus is optimally positioned over an artery by including an ultrasonic blood flow sensor configured to sense the flow of blood under the pressure transducer.
Patent AT-E325433-T1 (AT)
Inventor: KEEFER BOWIE G
IPC: B01D53/06
Filed: 1999-09-14
Granted: 2006-06-15
Abstract: An electrical current generating system consists of a fuel cell, and an oxygen gas delivery system. The fuel cell includes an anode channel having an anode gas inlet for receiving a supply of hydrogen gas, a cathode channel having a cathode gas inlet and a cathode gas outlet, and an electrolyte in communication with the anode and cathode channel for facilitating ion exchange between the anode and cathode channel. The oxygen gas delivery system is coupled to the cathode gas inlet and delivers oxygen gas to the cathode channel. The electrical current generating system also includes gas recirculation means coupled to the cathode gas outlet for recirculating a portion of cathode exhaust gas exhausted from the cathode gas outlet to the cathode gas inlet.
Patent AT-E244317-T1 (AT)
Inventor: VINE WENDY JANE
IPC: B22F3/17
Filed: 1999-09-02
Granted: 2003-07-15
Abstract: A dispersion strengthened mechanically alloyed aluminium based alloy is provided which is prepared by mechanical alloying and is characterized by improved isotropic strength, fracture toughness and corrosion resistance. The alloy system contains by weight 1.2 to 1.6% lithium, 4.0 to 6.0% magnesium, 0.15 to 0.7% carbon, up to 1% oxygen and up to 2.0% in total of one or more grain controlling elements to provide microstructural optimization and control, the balance aluminium save for incidental impurities.
Patent AT-E247936-T1 (AT)
Inventor: COLOMBO GERY
IPC: A61F5/01
Filed: 1999-11-11
Granted: 2003-09-15
Abstract: The invention relates to an automatic machine, which is used in treadmill therapy (walking therapy) of parapetic and hemiparetic patients. The machine automatically guides the patient's legs on the treadmill. The machine includes a driven and controlled orthotic device, which guides the legs in a physiological pattern of movement, a treadmill and a relief mechanism. Knee and hip joints of the orthotic device each include a drive. The orthotic device is stabilized on a treadmill with stabilizing means in such a manner that the patient does not have to keep his/her equilibrium. The othotic device can be adjusted in height and can be adapted to different patients.
Patent AT-E289057-T1 (AT)
Inventor: MASSON MICHEL
IPC: G01D9/00
Filed: 1999-09-15
Granted: 2005-02-15
Abstract: The invention relates to a device (10) for acquiring data. The inventive device has at least one sensor element (12) for acquiring the data and a storage element (13) for at least writing-in and reading-out the data acquired. The sensor element (12) and the storage element (13) are located on a support (11).
Patent AT-E289869-T1 (AT)
Inventor: DENTON DEAN A
IPC: B01J21/08
Filed: 1999-12-20
Granted: 2005-03-15
Abstract: A method of making frangible, spray dried agglomerate catalyst supports is provided, e.g. of silica gel, which possess a controlled morphology of microspheroidal shape, preferably a rough, scabrous appearance, and interstitial void spaces which penetrate the agglomerate. The agglomerates also possess a 4-250 micron particle size, 1-1000 m2/gm. surface area, and an Attrition Quality Index (AQI) of at least 10. The method comprises dry milling inorganic oxide particles, e.g. silica gel, wet milling the dry milled inorganic oxide particles (to preferably impart a colloidal segment of <1 micron particles), and spray drying the particles. The high AQI assures that the agglomerates are frangible and that polymerization performance is improved. The controlled morphology is believed to permit the constituent particles of the agglomerates to be more uniformly impregnated or coated with conventional olefin polymerization catalysts.
Patent DE-184770-T1 (DE)
IPC: D04B1/24
Filed: 1985-12-04
Abstract: A panty brief consists wholly or partly of elastic textile material, preferably made by knitting or crocheting, and is formed as a flat, substantially rectangular bag which is closed along three marginal zones (2,3,4). The bag is open in the whole extension of one longitudinal edge to provide a waist opening (7) at the non-connected marginal zones (6), and is provided with two leg openings (11).To produce such a panty brief, having inclined leg openings and a good fit, without any form of after-fashioning, inexpensively and by automatic machines, the leg openings (11) are located opposite one another in the two sides (1) of the bag in a position between the marginal zone (6) and the opposite marginal zone (4) so that two of the interconnected marginal zones (2, 3) are placed in the front and the back of the panty brief, while the third (4) is located in the crotch region (5) of the panty brief between the leg openings (11).
Patent DE-389323-T1 (DE)
IPC: C03B23/03
Filed: 1990-03-02
Abstract: The installation for curving or bending to convex form and tempering a sheet of glass (1) comprises means for heating the sheet and means for bringing this latter between elements (3, 4, 6, 7) for shaping said sheet. One of the series (3) of elements has a surface (3a) which is intended to come into contact with one of the faces of the glass sheet (1). The other series of elements (4, 6, 7) has a stationary portion (5) to which is attached at least one movable portion (6 or 7) which is capable of pivotal displacement through an angle corresponding to the curvature to be given to the glass sheet.
Patent DE-469145-T1 (DE)
IPC: F16H3/62
Filed: 1991-02-27
Abstract: PCT No. PCT/FR91/00159 Sec. 371 Date Oct. 24, 1991 Sec. 102(e) Date Oct. 24, 1991 PCT Filed Feb. 27, 1991 PCT Pub. No. WO91/13275 PCT Pub. Date Sep. 5, 1991.A transmission (1) has an input (2) connected to an engine (3). At a speed above idling, a centrifugal clutch (9) connects the engine to a pump (8) of a torque converter (7) and also to a sun gear (14) of a planetary gear train (13). A turbine (11) of the torque converter is connected to a ring gear (16) of the planetary gear train, and a planet carrier (18) is connected to an output (4) of the transmission. A free wheel (22) mounted between the ring gear and a stationary housing prevents reverse rotation of the ring gear. At low engine speeds, the power passes via the sun and planet gears through the planet carrier to the output, while reaction torque exerted by the planet gears on the ring gear is greater than forward torque transmitted through the torque converter, so that the ring gear is held stationary by the free wheel. In this condition, the planetary gear train acts as a mechanical speed reducer. As the engine speed increases, the torque transmitted by the converter to the ring gear exceeds the reaction torque of the planet gears, driving the ring gear in the forward direction at progressively increasing speeds that approach the speed of the planet carrier, thus progressively decreasing the speed reduction of the gear train. The planetary gear train serves to add the engine power received directly at the sun gear and via the hydraulic torque converter at the ring gear.
Patent DE-793460-T1 (DE)
Inventor: ISRAEL HENRY
IPC: A61F2/16
Filed: 1995-11-21
Abstract: An intraocular lens assembly for implantation in a human eye, said eye including a ciliary muscle and zonules controlled by the ciliary muscle, the assembly including: an optic having anterior and posterior surfaces depending from a common edge; at least two, preferably rigid, linkage arms, each being attached to the optic at a first position on the arm thereof and cooperating with ciliary muscle or the zonules at a second position on the arm; and at least two pivots, one of which is rotatably attached to each respective linkage arm intermediate the first and second positions.
Patent DE-1113963-T1 (DE)
Inventor: GIANNITELLI MARIO
IPC: B65B61/14
Filed: 1999-06-24
Abstract: The invention relates to a process to apply adhesive band on moving objects, comprising the steps of: pitch feeding the object on which the band must be applied, in such a way that all the objects make the same trajectory and that for each point of said trajectory the position of each object is defined and invariable; feeding a band to be applied to an application head; moving said application head according to a cyclic trajectory, along a generic plane parallel with respect to the object trajectory and intersecting the same, able to drive among the front and rear profiles of each pair of consecutive objects, while they move according to a continuous and uniform flow the movement of said application head being such to allow the adhesive band to drivingly slide with its not adhesive surface along the outer profile of the same head, to be able to have a contact point only with the front or rear profile of the object on which the adhesive band is being applied, to be able to have a contact point with the front profile of the object and, at the same time, a contact point with the rear profile of the preceding object on which the band is being applied and, at the same time, a contact point with the front profile of the following object, to be able to perfectly follow the two profiles, current, preceding or subsequent, to be able to cut the adhesive band in an intermediate point between the two contact points, to be controllable with respect to the number and kind of contact points, and to be controllable with respect to the cutting moment. The invention further relates to an apparatus to apply adhesive band on moving objects.
Patent ES-2109207-T1 (ES)
Title: Producto para el teñido oxidativo del cabello con un contenido de 2,5-diaminobenzonitrilos, asi como nuevos 2,5-diaminobenzonitrilos.
Inventor: KELLER HELMUT
IPC: A61K8/46
Filed: 1996-12-10
Abstract: LA PRESENTE INVENCION SE REFIERE A UN MEIDO PARA LA COLORACION POR OXIDACION DEL CABELLO QUE UTILIZA UNA COMBINACION DE UN AGENTE DE DESARROLLO Y UN AGENTE DE COPULACION. EL AGENTE DE DESARROLLO ES UN 2,5 DIAMINOBENZONITRILO DE LA FORMULA GENERAL (I): EN DONDE R{SUP,1} Y R{SUP,2} INDEPENDIENTEMENTE PUEDEN SER HIDROGENO, ALQUILO CON 1 A 6 ATOMOS DE CARBONO O HIDROXIALQUILO CON 2 A 4 ATOMOS DE CARBONO O DIHIDROXIALQUILO CON 3 O 4 ATOMOS DE CARBONO, SIEMPRE QUE LOS RADICALES R{SUP,1} Y R{SUP,2} NO CONTENGAN AL MISMO TIEMPO HIDROGENO O SU SAL SOLUBLE EN AGUA Y FISIOLOGICAMENTE COMPATIBLE. LA INVENCION SE REFIERE ASIMISMO A NUEVOS 2,5 - DIAMINOBENZONITRILOS.
Patent CY-1107646-T1 (CY)
Inventor: MORETTI GIORGIO
IPC: F04B15/02
Filed: 2007-06-04
Abstract: The invention concerns a concrete pump, of the type comprising a pair of pumping cylinders alternatively operating under the control of a backflow hydraulic pump - to draw concrete from a hopper and feed it, by way of a rocking valve (S-valve), into the transport and delivery duct - wherein said cylinders are provided with stops to control the starting movement of the S-valve. According to the invention, the speed of the piston stroke of said cylinders is modulated by being increased in the initial length of said stroke, and electronic means are provided to control said speed according to the maximum concrete capacity allowed by the pump. <IMAGE>
Patent CY-1108783-T1 (CY)
Inventor: JARUZEL KURT
IPC: E04G11/06
Filed: 2008-09-15
Abstract: The circular shuttering has at least one shuttering element (1) with skin (4) of adjustable curvature supported by supports (5) and fixing flanges (6). Between the fixing flanges (6) of the supports and the skin are intermediate members (9) so that the flanges can be fixed on same where they can swivel or tilt about their longitudinal extension.  The intermediate members can have threaded holes for screwing in fixing screws which pass through the flanges.