baber/WOPTO huggingface dataset:
Patent CA-2903176-A1 (CA)
Title: 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant idh
Inventor: CHO YOUNG SHIN
IPC: C07D413/14
Filed: 2014-03-13
Abstract: The invention is directed to a formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b and R3-R7 are described herein. The invention is also directed to compositions containing a compound of formula (I) and to the use of such compounds in the inhibition of mutant IDH proteins having a neomorphic activity. The invention is further directed to the use of a compound of formula (I) in the treatment of diseases or disorders associated with such mutant I DH proteins including, but not limited to, cell-proliferation disorders, such as cancer.
Patent CA-2903404-A1 (CA)
Title: In situ probe with improved diagnostics and compensation
Inventor: KRAMER JAMES D
IPC: F23N5/02
Filed: 2014-03-27
Abstract: A process combustion transmitter (10) is provided. The transmitter (10) includes a process probe (12) extendible into a flow of process combustion exhaust. The process probe (12) has a measurement cell (36) and a diffuser (32) that define a chamber (52) within the process probe. Electronic circuitry (42) is coupled to the measurement cell (32) and is configured to provide an indication relative to a combustion process based on an output signal of the measurement cell (32). A pressure sensor (50) is coupled to the electronic circuitry (42) and is fluidically coupled to the chamber (52). The electronic circuitry (42) is configured to provide an adjusted calibration based on pressure measured within the chamber (52) during a calibration.
Patent CA-2903778-A1 (CA)
Inventor: SCHROADER STEVEN
IPC: B65G47/71
Filed: 2014-02-28
Abstract: A conveyor machine (21) is provided. In another aspect, a singulator conveyor (25; 125; 225; 325) employs three-dimensionally obliquely skewed driven rollers (65) angularly offset from a primary feeding and downstream direction (89; 361), outboard of an adjacent driven conveyor (51; 151; 251; 351) having a top surface (53; 187; 253) moving in the primary feeding and downstream direction (89; 361). A further aspect provides a downstream moving conveyor belt (51; 151; 351) or rollers (251) which are vertically higher than the adjacent outboard skewed and converging driven rollers (65; 165; 265; 365).
Patent CA-2905391-A1 (CA)
Title: Methodes et compositions servant a augmenter l'efficacite de la modification de gene cible au moyen de la reparation de gene modulee par un oligonucleotide
Inventor: BEETHAM PETER R
IPC: A01H1/00
Filed: 2014-03-14
Abstract: L'invention concerne des procédés améliorés destinés à la modification de gènes dans les cellules de plantes, les plantes et les semences dérivées de celles-ci. Plus particulièrement, l'invention se rapporte à l'efficacité augmentée de mutation de gène ciblé en combinant les oligonucléotides de réparation de gène avec des approches qui améliorent la disponibilité de constituants des mécanismes de réparation de gène de cellule cibles.
Patent CA-2906713-A1 (CA)
Title: Systemes et procedes de fourniture de diagnostics de cloture electrique ameliores
Inventor: DEMAO JACK
IPC: H05C1/04
Filed: 2014-03-14
Abstract: La présente invention concerne une unité de commande de clôture électrique comprenant un générateur de signal, un premier récepteur de signal, un second récepteur de signal, une unité de traitement et de commande de signal et une interface de communication. Le générateur de signal génère et émet un signal de puissance réglable le long d'un chemin de conduction de la clôture électrique. Les récepteurs de signal échantillonnent les sorties de signal au niveau d'une extrémité excitée et au niveau d'une extrémité ouverte de la ligne de clôture. L'unité de traitement et de commande de signal reçoit et analyse la première sortie de signal et la seconde sortie de signal. L'interface de communication émet des résultats de traitement de la première sortie de signal et de la seconde sortie de signal vers un centre de service. Le signal de puissance peut être réglé sur un niveau de puissance de capacité quelconque entre un niveau de puissance maximum et un niveau de puissance minimum de sorte à correspondre à une charge de la clôture électrique. L'invention concerne également des procédés de surveillance de clôture électrique consistant à régler un niveau de puissance du signal de puissance réglable.
Patent CA-2912046-A1 (CA)
Inventor: GINGRAS LUC
IPC: D21D1/30
Filed: 2015-11-16
Abstract: A rotor cap assembly has been conceived using multiple wedge-shaped rotor cap segments, in which the cap segments are disposed on a cap segment retainer and in which the cap segment retainer pilots the multiple rotor cap segments at a diameter intermediate the cap segments' outer diameter and the cap segments' middle diameter. By piloting multiple rotor cap segments with retaining means on the cap segment retainer and positioning means on the multiple cap segments, the rotor cap segments and cap segment retainer assembly may be fixed to a plate holder or directly to a rotor disc of a refiner without substantially altering either the plate holder or the rotor disc.
Patent CA-2912835-A1 (CA)
Inventor: RIGHETTI ALESSANDRO
IPC: A24F40/42
Filed: 2014-04-09
Abstract: The electronic smoking substitutive device comprises a tubular body (2) of rigid material, inside which a rechargeable electric battery and an atomizer suitable to be powered by said electric battery are arranged. Activation means (5) allow to operate the heating of said atomizer by the electric battery. A tank (10) containing an inhalable substance in aqueous solution is suitable to be placed in disposable manner in contact with said atomizer.
Patent CA-2916563-A1 (CA)
Title: Hydrophobic polyurethane adhesive
Inventor: ELING BEREND
IPC: C09J175/04
Filed: 2014-06-16
Abstract: The present invention relates to a polyurethane adhesive containing an isocyanate component A and a polyol component B, where the isocyanate component A contains at least one diisocyanate or polyisocyanate and the polyol component B contains the alkylation product of a mixture of castor oil or ricinoleic acid (i), an aromatic di- or polyol (ii), an OH-functional compound having aliphatically bonded OH groups and OH functionality of from 1 to 8 (iii), and also optionally a compound (iv) selected from the group consisting of cyclic anhydrides of dicarboxylic acids and optionally a compound (v) selected from the group consisting of cyclic mono- and diesters. The present invention further relates to a process for adhesive bonding with use of the polyurethane adhesive according to the invention, to an item adhesively bonded with use of the polyurethane adhesive, and to the use of said item in the construction of wind turbines.
Patent CA-2922725-A1 (CA)
Title: Pan and selection gesture detection
Inventor: DANTON STEPHEN MICHAEL
IPC: G06F3/0485
Filed: 2014-09-29
Abstract: A user interface that has a canvas that is extendable in an extendable dimension and on which multiple selectable elements may be placed. In this context, when a selecting control is associated with a particular selectable element, and further user gestures are provided, a pan detection mechanism is configured to distinguish between an intent to pan the canvas and an intent to select the particular selectable element. When a selecting control is associated with a particular orthogonally scrollable element, the pan detection mechanism may be distinguish between an intent to pan the canvas and an intent to scroll the orthogonally scrollable element in a direction perpendicular to the extendible dimension of the canvas.
Patent CA-2923885-A1 (CA)
Title: Depth key compositing for video and holographic projection
Inventor: CROWDER ASHLEY
IPC: H04N5/74
Filed: 2014-09-12
Abstract: According to embodiments herein, depth key compositing is the process of detecting specific desired portions/objects of a digital image using mathematical functions based on depth, in order to separate those specific portions/objects for further processing. In one particular embodiment, a digital visual image is captured from a video capture device, and one or more objects are determined within the digital visual image that are within a particular depth range of the video capture device. From there, the one or more objects may be isolated from portions of the digital visual image not within the particular depth range, and the isolated objects are processed for visual display apart from the portions of the digital visual image not within the particular depth range. Also, in certain embodiments, the detected portion of the digital image (isolated objects) may be layered with another image, such as for film production, or used for holographic projection.
Patent CA-2924305-A1 (CA)
Inventor: YUAN SIMON
IPC: B03B9/02
Filed: 2016-03-15
Abstract: A process for the in-situ treatment of tailings in a containment area having a tailings layer comprising fine solids and water, is provided comprising: adding a flocculant, a coagulant, a hydrophobicity modifying agent, or any combination thereof, into a portion of the tailings layer; mixing the portion of the tailings layer and flocculant, coagulant, collector, or combinations thereof, to form in-situ treated tailings; and allowing the in-situ treated tailings to dewater and/or consolidate in-situ in the tailings containment area.
Patent CA-2927425-A1 (CA)
Inventor: MERLEN ALAIN
IPC: F04B43/04
Filed: 2014-10-24
Abstract: The invention relates to a method for generating a flow of fluid, implemented in a device comprising a membrane (2) provided with at least one hole (20) and means (4) generating back-and-forth movements, wherein a flow is generated through the membrane by actuating said membrane, at least in the region of said at least one hole (20), according to a mode of deformation of said at least one hole, causing said at least one hole to open and close and disturbing the fluid in order to generate said flow. The invention also relates to a device suitable for implementing the method.
Patent CA-2927636-A1 (CA)
Inventor: BORGES FILHO AROLDO GASPAR
IPC: B60J5/00
Filed: 2015-01-30
Abstract: A vertical sealing arrangement (10) to be used between doors (2, 3) of utility motor vehicles (1) of various types, such as pickups, trucks, SUVs, sedans, hatchbacks and the like with front and rear doors without the side pillar, the so-called B pillar, is formed by two mouldings, the top collector (11) and the bottom discharger (12), which are interconnected by an extruded profile (13) having at least one hollow longitudinal cavity (22) the lumen of which interconnects the inside volume of the collector (11) to the inside volume of the discharger (12), thus defining a flow path for water and dust deposited on the upper part of the vehicle (1) down to the lower part of the vehicle.
Patent CA-2929303-A1 (CA)
Inventor: TESSIER LYNN
IPC: E21B17/10
Filed: 2016-05-09
Abstract: A rod guide for installation on an intermediate section along a rod without need for access to ends thereof, and which provides a synthetic, low friction surface for reduced contact to either the guide or surrounding tubing. The rod guide has a robust construction for secure attachment to the rod, yet is characterized by ease of installation and replacement. Various outer profiles of low friction surface can be employed, and the low friction surface can be replaced without removing the entire rod guide. Each rod guide can be installed periodically along a rod such as through a work window installed above blow out preventer (BOP) or pack-off element.
Patent CA-2931249-A1 (CA)
Inventor: BLANK JUTTA
IPC: A61K31/407
Filed: 2014-11-20
Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Patent CA-2931641-A1 (CA)
Inventor: WU CHENGBIN
IPC: C07K16/00
Filed: 2014-12-24
Abstract: The present invention provides multivalent and multispecific binding proteins that are capable of binding two or more antigens, or two or more epitopes. The present invention also provides methods of making and using such multivalent and multispecific binding proteins, including methods of using such binding proteins for prevention or treatment of various diseases, or for detecting specific antigens in vitro or in vivo.
Patent CA-2931986-A1 (CA)
Inventor: SKOLAUT ALEXANDER
IPC: C07K16/22
Filed: 2015-01-12
Abstract: Herein is reported a polypeptide comprising a first polypeptide and a second polypeptide each comprising in N-terminal to C-terminal direction at least a portion of an immunoglobulin hinge region, which comprises one or more cysteine residues, an immunoglobulin CH2-domain and an immunoglobulin CH3-domain, wherein i) the first polypeptide comprises the mutations 1253A, H310A and H435A and the second polypeptide comprises the mutations H310A, H433A and Y436A, or ii) the first polypeptide comprises the mutations 1253A, H310A and H435A and the second polypeptide comprises the mutations L251D, L314D and L432D, or iii) the first polypeptide comprises the mutations 1253A, H310A and H435A and the second polypeptide comprises the mutations L251S, L314S and L432S.
Patent CA-2932258-A1 (CA)
Inventor: GARDEN EUAN PETER
IPC: G06F9/50
Filed: 2014-12-03
Abstract: Aspects of the present invention relate to a multimode gaming server with different types of computing resources provided within the server. The different computing resources can be optimized for different computing tasks. For example, a first type of resource can be optimized for producing high definition graphics and a second type of resource for enterprise computing. Each resource may be activated or deactivated as demand for different computing tasks change throughout the day. In one aspect, the resources are different chip sets in different mother board sockets. In one aspect, provisioning of the other components (e.g., cooling, power supply, network bandwidth) in the multimode server is not adequate for both computing resources to run simultaneously.
Patent CA-2936438-A1 (CA)
Inventor: HAYSLETT STEVEN L
IPC: B62M6/75
Filed: 2016-07-18
Abstract: A number of variations may include a product that may comprise a gear set, and first, second and third mechanical mechanisms. Each mechanical mechanism may alternatively be open or closed and each may be connected to the gear set. The mechanical mechanisms may be variously open or closed providing a number of gear ratios through the gear set. A  fourth mechanical mechanism or a fixed connection may be included. A mode of operation may be provided where the first, second and third mechanical mechanisms are open, and the fourth mechanical mechanism may be closed or the fixed connection may be provided.
Patent CA-2936614-A1 (CA)
Inventor: LAVIAL FABRICE
IPC: C12N5/074
Filed: 2015-01-13
Abstract: The invention relates to a method for producing induced pluripotent stem cells (iPS) by culturing somatic cells subjected to a cellular reprogramming method, characterised in that the somatic cells are cultured in the presence of netrin-1 or an analogue of netrin-1 at least at the beginning of the cellular reprogramming method.
Patent CA-2937730-A1 (CA)
Title: Portable water feeder
Inventor: OUELLETTE JAMES-ROY
IPC: E03B3/02
Filed: 2016-08-02
Abstract: A portable water feeder for collecting rain water for bees, butterflies and many other uses has a vessel in which rain water is collected. A filter removes impurities from the rain water and a wind-powered agitator maintains the water in motion to minimize the build-up of algae. A valve controls the quantity of water which flows from the vessel to a watering station where the water is available for use.
Patent CA-2938476-A1 (CA)
Inventor: BIGGADIKE KEITH
IPC: C07D487/04
Filed: 2015-02-18
Abstract: Compounds of formula (I) and salts thereof: (I) wherein R1 is hydrogen, methyl or (CH2 )2 OR3, R2 is methyl or (CH2)2 OR4, or R1 and R2, together with the nitrogen atom to which they are attached, are linked to form a 5-or 6- membered heterocyclyl wherein the 6-membered heterocyclyl is optionally substituted by two hydroxy substituents; R3 and R4 are each independently hydrogen or methyl; and n is an integer having a value of 5 or 6, are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment or prevention of various disorders, for example the treatment or prevention of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.
Patent CA-2939019-A1 (CA)
Title: Electric submersible pump components
Inventor: CHANG LYE HENG
IPC: E21B43/12
Filed: 2015-02-11
Abstract: An electric submersible pump (ESP) can include a shaft; an electric motor configured to rotatably drive the shaft; a housing; a stack of diffusers disposed in the housing; and impellers operatively coupled to the shaft. Various other apparatuses, systems, methods, etc., are also disclosed.
Patent CA-2939609-A1 (CA)
Inventor: XU YUEHUA
IPC: B33Y70/00
Filed: 2016-04-25
Abstract: L'invention concerne un procédé de fabrication additive permettant de fabriquer un composant composite de matrice métallique comprenant la fusion d'un mélange de poudre avec un faisceau électronique. Le mélange de poudre comprend du carbure de tungstène en poudre dans une quantité de 45% en poids à 72% en poids du mélange de poudre et un liant en poudre dans une quantité de 28% en poids à 55% en poids du mélange de poudre. Le liant en poudre comprend du bore, du silicium et du nickel. L'invention concerne également des compositions de matrice métallique et un trépan de forage comprenant un corps de trépan composé desdites compositions de matrice métallique.
Patent CA-2940854-A1 (CA)
Inventor: JORGEN FJELDVIK HANS
IPC: F16B7/00
Filed: 2016-09-01
Abstract: The present invention relates to a system for fastening an elongated composite member to a column 2 extending through an opening in the elongated composite member 1. The elongated composite member 1 comprises an opening formed by a first aperture having a first peripheral edge and a second aperture having a second peripheral edge through the composite wall member. A stress distribution member 31 having a conical section 38 extends between the first and second apertures. The invention also relates to a stress distribution member 31 of a composite material having a frustum-shaped section and a pylon for power lines.
Patent CA-2941555-A1 (CA)
Title: Data transmission system, terminal device, program, and method
Inventor: MORITA KENICHIRO
IPC: G06F13/00
Filed: 2015-02-04
Abstract: A data transmission system in which a plurality of terminal devices connected to a communication network transmit or receive content data between the terminal devices, wherein at least one terminal device which receives the content data is provided with: a code amount change request unit (12) which, on the basis of an output signal output time interval corresponding to predetermined content data, transmits a code amount reduction request that is a request to reduce the code amount of the content data, designating the transmission source of the content data as a destination; and a code amount change unit (13) which in response to the code amount reduction request the transmission source of which is another terminal device, reduces the code amount of content data corresponding thereto.
Patent CA-2943540-A1 (CA)
Inventor: BOITANO ANTHONY
IPC: C12N5/0789
Filed: 2009-10-29
Abstract: Linvention concerne lutilisation dun agent capable dantagoniser lactivité et/ou lexpression du récepteur dhydrocarbure daryl et/ou dun effecteur en aval de la voie des récepteurs dhydrocarbure daryl pour la mise en contact avec la souche hématopoïétique et les cellules progénitrices pour accroître le nombre de souches et de cellules progénitrices. Les cellules souches hématopoïétiques développées peuvent être utilisées dans une transplantation autologue ou allogène pour le traitement de patients avec des maladies dimmunodéficience et des maladies auto-immunes héréditaires et divers troubles hématopoïétiques pour reconstituer les lignées de cellules hématopoïétiques et la défense du système immunitaire.
Patent CA-2943629-A1 (CA)
Inventor: CLAXTON RICHARD L
IPC: E02F9/26
Filed: 2015-04-16
Abstract: A method of calibrating strain sensors operatively associated with a machine may involve the steps of: Calculating, for each of n loading conditions, at least one structural load associated with at least one member of the machine to produce n calculated structural loads corresponding to the n loading conditions; measuring, for each of n machine positions, at least one strain associated with the at least one member of the machine to produce n measured strains corresponding to the n loading conditions; and determining curve fit parameters from said n calculated structural loads and said n measured strains, the curve fit parameters relating measured strain and structural loads over n loading conditions.
Patent CA-2943734-A1 (CA)
Title: Hemostatic pharmaceutical composition
Inventor: SAIJO HAYATO
IPC: A61L31/00
Filed: 2014-08-06
Abstract: [Problem] The present invention addresses the problem of providing a hemostatic pharmaceutical composition which has higher usability compared with conventional hemostatic agents each utilizing a biogel, and which can be formed into a transparent and homogeneous hydrogel in a broad pH range. [Solution] A hemostatic pharmaceutical composition containing a (sugar chain)-polypeptide complex is provided, said hemostatic pharmaceutical composition being characterized in that the polypeptide in the (sugar chain)-polypeptide complex is a polypeptide comprising an amino acid sequence in which a polar amino acid residue and a non-polar amino acid residue are arranged alternately, wherein one or multiple sugar chains are bound to the polypeptide.
Patent CA-2944717-A1 (CA)
Inventor: MODRUSAN ZORA
IPC: C40B30/04
Filed: 2015-05-22
Abstract: Provided are therapies related to the treatment of pathological conditions, such as cancer.
Patent CA-2949166-A1 (CA)
Inventor: BRANNOCK SAMUEL LINCOLN
IPC: B65D43/02
Filed: 2016-11-18
Abstract: A lid for a container is described. The lid has a basin that is designed to enhance the user's olfactory experience when drinking a beverage from the container and lid. As the user tilts the container and lid to take a drink, the beverage pours through an opening on the basin valley and flows across a sipping surface area to the user's mouth, thus allowing the beverage to aerate, evaporate, and cool. The basin is sized and dimensioned to channel and concentrate the vapor rising from the beverage towards the user's nose as the user sips the beverage. The basin and the opening are sized and dimensioned to provide a comfortable and secure feeling when drinking hot beverages. In this rummer, the lid enhances the drinker's olfactory experience and provides better controllability of the flow of a hot beverage to prevent burn injuries.
Patent CA-2949553-A1 (CA)
Inventor: CHU YIFANG
IPC: A23L33/00
Filed: 2015-05-21
Abstract: A composition and method for an avenanthramide-enriched, oat-based product having improved health effects. The oat-based product includes an avenanthramide ingredient having avenanthramides 2c:2p:2f in ratios comprising at least one of 1:1:1 or 1:2:2. More particularly, the avenanthramide ingredient may be derived synthetically or recovered from processing raw oats into constituent oat fractions.