baber/WOPTO huggingface dataset:
Patent CA-2318260-A1 (CA)
Title: Solid pharmaceutical compositions containing miltefosine for oral administration in the treatment of leishmaniasis
Inventor: SAUERBIER DIETER
IPC: A61K47/38
Filed: 1998-01-22
Abstract: The present invention relates to new solid pharmaceutical compositions containing hexadecylphosphocholine (miltefosine) for oral administration in the treatment of leishmaniasis, a process for the manufacture of said pharmaceutical composition, a dosage scheme for oral administration of said pharmaceutical composition in the treatment of leishmaniasis, and finally a combination comprising said solid pharmaceutical composition, an antiemeticum, and/or an antidiarrhoeal.
Patent CA-2319960-A1 (CA)
Title: Distribution device intended to fit a container
Inventor: BONNINGUE PHILIPPE
IPC: A47K5/12
Filed: 2000-09-15
Abstract: The shape of the pump base part (11) is such that friction is created between the pumping piston (20) and the base when the pumping volume is a minimum and that there is an absence of friction or minimal friction when the piston is in a position between its two extremes of motion.
Patent CA-2323231-A1 (CA)
Title: Qualitative differential screening
Inventor: TOCQUE BRUNO
IPC: C12Q1/68
Filed: 1999-03-11
Abstract: The invention concerns a method for identifying and/or cloning nucleic acid regions representing qualitative differences associated with alternative splicing events and/or with insertions, deletions located in RNA transcribed genome regions, between two physiological situations, comprising either hybridisation of RNA derived from the test situation with cDNA's derived from the reference situation and/or reciprocally, or double-strand hybridisation of cDNA derived from the test situation with cDNA's derived from the reference situation; and identifying and/or cloning nucleic acids representing qualitative differences. The invention also concerns compositions or banks of nucleic acids representing qualitative differences between two physiological situations, obtainable by the above method, and their use as probe, for identifying genes or molecules of interest, or still for example in methods of pharmacogenomics, and profiling of molecules relative to their therapeutic and/or toxic effects. The invention further concerns the use of dysregulation of splicing RNA as markers for predicting molecule toxicity and/or efficacy, and as markers in pharmacogenomics.
Patent CA-2324486-A1 (CA)
Inventor: NOVAK DENES
IPC: C04B7/21
Filed: 2000-10-26
Abstract: A hydraulic binder containing a glassy bulky slag milled to a fineness above 5000 cm2/g Blaine and wherein the latently hydraulic blast furnace slag has a glassiness above 93%, contains 34 to 40% Si02, 34 to 37% CaO and above 9% and previously below 13% Al2O3. The (CaO+MgO) /(Al2O3+SiO2) ratio ranges from 0.88 to 0.98. Preferably the binder contains 0.5 to 5% porcelain cement clinker or porcelain cement. The above conditions can be met by mixing several slags.
Patent CA-2326131-A1 (CA)
Title: Optical transmission line, negative dispersion optical fiber used for the optical transmission line, and optical transmission system comprising optical transmission line
Inventor: MUKASA KAZUNORI
IPC: H04B10/2525
Filed: 2000-02-22
Abstract: An optical transmission line of low nonlinearity having a small dispersion in the wavelength band (L-band) between 1570 and 1620 nm and enabling wavelengthmultiplex optical transmission in the 1520-1620 nm band including the wavelength band conventionally researched. The transmission line is made up of one or more blocks, each constituted by sequentially connecting an optical amplifier (32), an SMF (33) and an L-RDF (34) between an optical transmitter (31) and an optical receiver (35). The SMF (33) has a positive dispersion value and a positive dispersion gradient in the preset wavelength band in the L-band. The L-RDF (34) is a negative dispersion optical fiber of line type for compensating for the dispersion and dispersion gradient in the preset wavelength band of the SMF (33). The SMF (33) and the L-RDF (34) are connected, and the dispersion value in the preset wavelength band over the entire optical transmission line is -1 to 1 ps/nm/km.
Patent CA-2327988-A1 (CA)
Inventor: MALINOWSKI KLAUS
IPC: G06F13/40
Filed: 2000-12-08
Abstract: The present invention relates to a switching system for interconnecting a plurality of computer user terminals or workstations each having user interface devices, including a keyboard, a video display unit, and a cursor control device or mouse (KVM), with a plurality of computers in a computer network, allowing a user to access any one or more of said computers from the user interface devices of a single terminal or workstation. It is denoted "high end" because of the potentially large number of computers which may be interconnected with the system.
Patent CA-2328450-A1 (CA)
Inventor: KITE J SELLERS III
IPC: D04C1/06
Filed: 1999-04-16
Abstract: A braided tubular article (10) comprises a tubular form of helically braided yarns (12) to which is coupled a plurality of spaced axially extending restraining elements (14), conveniently as warp elements braided with the tubular form. The yarns (12) are braided with a small helix pitch that permits the tubular form to be extended axially and contract radially onto a substrate as a protective sleeve. The warp elements are essentially inextensible and frictional coupling between them and the braid yarns inhibits extension of the article, permitting it to be handled and passed over a substrate before applying a deliberate extension force to overcome the friction and contract it into the substrate. The restraining elements may be other than branded warp elements and the extension-inhibiting coupling may be a disruptable bond instead of, or supplementing, friction. Frictionally acting warp elements permit the extended article to assume a bent form in one or more directions. The warp elements may be positionally floating or anchored with respect to the braid yarns.
Patent CA-2330679-A1 (CA)
Title: Process and apparatus for cutting of discrete components of a multi-component workpiece and depositing them with registration on a moving web of material
Inventor: RAJALA GREGORY JOHN
IPC: A61F13/15
Filed: 1999-05-24
Abstract: This invention pertains to a machine and process for cutting discrete workpiece components from webs of material, precisely registering them with respect to one another, and depositing them with precise registration onto a constantly moving web of material, the webs of material optionally all moving at different speeds. In a particular embodiment of the invention, a process for manufacturing a multi-component absorbent personal hygiene article is described.
Patent CA-2331448-A1 (CA)
Inventor: HUBERT JAMES F
IPC: C08J11/00
Filed: 1999-05-07
Abstract: Acrylic resin-based plastisol compositions are improved by the incorporation of recycled paint polymer containing uncured resin (i.e., substances containing functional groups capable of undergoing chemical reaction). The compositions may be used to apply coatings to stiff articles having a tendency to vibrate such as metal automobile parts and the like. Such coatings are effective in suppressing mechanical vibration, reducing the noise of particle impact, and/or lowering the amount of air vibration in a cavity.
Patent CA-2331771-A1 (CA)
Title: Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors
Inventor: ZAGHOUANI HABIB
IPC: C07K14/47
Filed: 1999-07-06
Abstract: A fusion protein for the alleviation of symptoms associated with an autoimmune disorder comprising an immunoglobulin or portion thereof linked to one or more autoantigenic polypeptides or fragments thereof, wherein said immunoglobulin or portion thereof is capable of binding to an Fc receptor and being endocytosed by an antigen-presenting cell, and said one or more autoantigenic polypeptides or fragments thereof provides more than one t cell receptor peptide agonist for presentation on the surface of said antigen-presenting cell upon endocytic processing. Said autoantigenic polypeptides may comprise at least a portion of myelin basic protein or at least a portion of proteolipid protein. Method to alleviate symptoms associated with an autoimmune disorder in a patient in need thereof comprising the steps of providing a composition comprising said fusion protein and administering a therapeutically effective amount of said composition to said patient.  Autoimmune disorders may include multiple sclerosis, lupus, rheumatoid arthritis, scleroderma, insulin-dependent diabetes and ulcerative colitis.  Method for presenting multiple T cell receptor agonists on the surface of a professional or nonprofessional antigen-presenting cell comprising the steps of providing said fusion protein, contacting said fusion protein with at least one Fc receptor present on the surface of a professional or nonprofessional antigen-presenting cell, whereby the fusion protein is internalized by the antigen-presenting cell, whereby the fusion protein is internalized by the antigen-presenting cell, and endocytically processing the internalized fusion protein to provide more than one T cell receptor peptide agonist, wherein the provided T cell receptor agonists are presented on the surface of the antigen-presenting cell.
Patent CA-2332208-A1 (CA)
Inventor: EKINS SEAN
IPC: G06F17/30
Filed: 2001-01-24
Abstract: The present invention relates to novel screening methods which enable the selection of neurokinin-1 (NK-1) receptor antagonist compounds which do not possess significant inhibitory potency towards cytochrome P450 enzymes, in particular, CYP2D6. The present invention also relates to a method of generating a pharmacophore model for the CYP2D6 inhibitory activity of NK-1. receptor antagonist compounds; to methods for the discovery of molecules that are potential NK-1 receptors antagonist compounds which do not possess significant inhibitory potency towards the CYP2D6 enzyme; to methods of modeling the features of the CYP2D6 pharmacophore useful in selecting NK-1 receptor antagonist molecules which do not possess significant potency towards CYP2D6. Further, the invention also relates to pharmaceutical compositions comprising a NK-1 receptor .antagonist compound which does not possess significant potency towards the CYP2D6 enzyme identified by methods of the invention; to the users of a NK-1 receptor antagonist compound identified by the methods of the invention for the manufacture of medicaments and for the treatment of a condition, a disorder or a disease in a mammal for which an NK-1 antagonist receptor compound identified by the method of the invention is therapeutically useful.
Patent CA-2333110-A1 (CA)
Inventor: HARDY PHILIP MILES
IPC: B42D15/08
Filed: 1999-05-18
Abstract: At least one surface of a pressure seal form (2) will comprise one or more areas of pressure seal adhesive distributed such that when the form (2) is folded in a predetermined manner at least two regions of pressure seal adhesive (17, 18, 19) come into contact with each other. The strength of adhesive used in making such forms (2) is a highly critical factor in facilitating their production while providing evidence of unauthorised tampering, e.g. by tearing of the paper substrate of a sealed form (2). Many adhesives were previously regarded as unsatisfactory, for example in giving an adhesive to adhesive bond weak enough to permit the opening of an unweakened form (2) without any indication that tampering has occurred. The provision of a local weakening of the form (2) in at least a part of a said region enables the use of a larger range of adhesives, including at least some of those previously rejected. The weakening could take the form (2) of partial or complete cutting/perforation; scuffing, scratching, scoring or abrading; or creasing or embossing.
Patent CA-2335096-A1 (CA)
Inventor: MULERO JULIO
IPC: C07K19/00
Filed: 1999-07-16
Abstract: The invention provides novel polynucleotides isolated from cDNA libraries of  human fetal liver-spleen and macrophage as well as polypeptides encoded by these polynucleotides and mutants or variants thereof. The polypeptides correspond to a novel human CD39-like protein. Other aspects of the inventio n include vectors containing polynucleotides of the invention and related host  cells as well as processes for producing novel CD39-like polypeptides, and antibodies specific for such polypeptides.
Patent CA-2335203-A1 (CA)
Title: Entertainment system and data communication network system
Inventor: CHATANI MASAYUKI
IPC: H04W4/06
Filed: 2000-04-13
Abstract: An object of the present invention is to construct a data communication network system having as a component an entertainment system that includes an entertainment apparatus to which a portable information communication terminal is freely detachably attached. In the data communication network system in accordance with the present invention, the entertainment system transmits an identification number assigned to the portable information communication terminal and input data or a message to a computer system acting as a server over a bi-directional communication network. The computer system transmits a command, which is responsive to the identification number and the input data or message, to a computer system having a database over a link realized with a LAN. The computer system retrieves information, which is associated with the input data or message, from the database, and transmits (broadcasts) the information together with the identification number to the portable information communication terminal through the link realized with radiocommunication over a unidirectional communication network. A networked data processing system serving as an asynchronous message exchange system or an asynchronous data summation and results distribution system can be constructed.
Patent CA-2335330-A1 (CA)
Inventor: MACKIE DAN
IPC: C22B3/02
Filed: 2001-02-09
Abstract: The invention provides an apparatus for treating a particulate ore for the recovery of contained values therefrom. The apparatus has a tank for receiving a liquid, the tank having a feed end and a discharge end and a bottom means for feeding the particulate ore to the tank at the feed end, and a manifold head tank for receiving the liquid for fluidizing the particulate ore. The apparatus also includes distribution means for intermittently distributing the liquid in the tank, means for withdrawing the ore particles at the tank discharge end, and means at the bottom of the tank at the base of the bed of coarse particulate material for withdrawing the liquid therefrom.
Patent CA-2335411-A1 (CA)
Title: Medical devices for modulation of apoptosis and immune response
Inventor: GRANT JASON R
IPC: C07K14/075
Filed: 2001-03-02
Abstract: The present invention relates to polynucleotide and polypeptide molecules for Adenovirus 2 E3/6.7K, and related proteins such as E3/6.7K from other viruses and their human homologues. In one embodiment polynucleotide and polypeptide molecules comprise the SED domain of TACI and novel human protein similar to TACI. The polypeptides, and polynucleotides encoding them, may be used as a therapeutic for preventing in-stent restenosis and inflammation.
Patent CA-2335595-A1 (CA)
Inventor: CARSON DENNIS A
IPC: C07D475/02
Filed: 1999-06-24
Abstract: L'invention concerne des composés antagonistes bifonctionnels de certaines cascades d'activation, qui inhibent les réponses inflammatoires associées au TNF-.alpha. et la prolifération des fibroblastes in vivo et in vitro en bloquant l'activation des kinases c-Jun et p38. Les composés de l'invention possèdent davantage qu'une activité additionnelle par rapport aux différents constituants de chaque composé. Un de ces constituants bloque l'activation de la kinase c-Jun, tandis que l'autre bloque l'activation de la kinase p38, sans que ces activités se chevauchent. Les composés de l'invention n'inhibent de manière appréciable ni l'activité de l'AMPc phosphodiestérase, ni l'hydrolyse de l'acide phosphatidique, et ils ne sont ni cytotoxiques ni cytostatiques. L'invention concerne également des techniques qui permettent d'utiliser ces nouveaux composés comme anti-inflammatoires. Ces techniques sont censées protéger un vertébré hôte des réponses inflammatoires (par exemple après angioplastie) ou atténuer chez lui lesdites réactions, limiter la fibrose (par exemple dans la cirrhose du foie), et inhiber la sénescence cellulaire, l'apoptose cellulaire et l'immunosuppression cutanée induite par les ultraviolets.
Patent CA-2336429-A1 (CA)
Inventor: KRAJCIR DEZI A
IPC: A43B7/32
Filed: 2001-02-13
Abstract: A metatarsal protector for footwear consists of a body molded from resilient plastics material, the material being sufficiently flexible to be molded flat and bent to a saddle shape when incorporated into the footwear. The range of hardness required for the material is between 35 and 60 Shore (Durometer A). The protector comprises a plurality of ridged projections protruding from one surface, forming a plurality of open-mouthed recesses, which may be circular, rectangular or triangular. The projections may be more closely spaced at and around the usual impact point. The body may be provided on its opposite surface with second projections, each registering with a respective recess at the first surface; these are the same shape and size, or slightly smaller, so that on deformation they enter their respective recesses, increasing the impact absorption. The resultant boots can meet the Mt75 impact classification.
Patent CA-2336753-A1 (CA)
Title: Method for measuring polarization dependent loss and insertion loss
Inventor: VILLENEUVE ALAIN
IPC: G01M11/00
Filed: 2001-02-14
Abstract: This invention provides a method of obtaining accurate measurements of polarization dependent loss and insertion loss during the tests aiming at measuring the polarization properties of optical components. This is achieved by taking into account every polarization disturbance in the line between generation of known states of polarization and the device under test. The method involves computing within a desired range of wavelengths either the transfer matrix of each polarization perturbing element or of all polarization perturbing elements as a whole, and compensating for errors introduced by these polarization perturbing elements.
Patent CA-2337097-A1 (CA)
Inventor: LAMBERT JAMES L
IPC: A61B5/00
Filed: 1999-07-12
Abstract: This invention is a non-invasive method for determining blood level of an analyte of interest, such as glucose, comprising generating an excitation laser beam (10) (e.g., at a wavelength of 700 nanometers to 900 nanometers); focusing (13) the excitation laser beam into the anterior chamber of an eye of the subject so that aqueous humor in the anterior chamber is illuminated; detecting (32) (preferably confocally (22) detecting) a Raman spectrum from the illuminated aqueous humor; and then determining the blood glucose level (or the level of another analyte of interest) for the subject from the Raman spectrum.  Preferably, the detecting step is followed by the step of subtracting a confounding fluorescence spectrum from the Raman spectrum to produce a difference spectrum; and determining the blood level of the analyte of interest for the subject from that difference spectrum, preferably using linear or nonlinear multi-variate analysis such as partial least squares analysis. Apparatus for carrying out the foregoing method is also disclosed.
Patent CA-2337330-A1 (CA)
Title: Method and product for protecting an object with a soluble binder security print
Inventor: TRANTOUL FRANCOIS
IPC: B42D15/10
Filed: 2000-05-17
Abstract: A security imprint (4) is interposed between a protective film (2) of synthetic material and a surface (8) of an object (9) to be protected, onto which surface the film is glued by means of an adhesive (3). The security imprint (4) includes an ink composition having at least one pigment, a bonding agent, and a soluble agent. The soluble agent dissolves in a solvent that is intended to release the adhesive (3) and produces a visible stain.
Patent CA-2337724-A1 (CA)
Inventor: FARDIN RAHIM
IPC: F41G3/26
Filed: 2001-02-23
Abstract: The harness system for identification purposes has several harnesses (101, 111), which are provided with complementary parts (102, 112), which are connected with electrically conducting cables (105, 115), of connecting buttons in order to mechanically connect the harnesses with each other and simultaneously to provide electrical connections via the cables between detectors fastened on the harness system and other electronic components. The connecting buttons are preferably snap fasteners having respectively one head part (102) and one hollow part (112).
Patent CA-2338824-A1 (CA)
Inventor: MITCHELL LES
IPC: G07F5/00
Filed: 2001-02-28
Abstract: The present invention is for an electronic mechanism for controlling the operation of a newspaper vending machine comprising a microprocessor having a first program code adapted to control a plurality of electromechanical devices associated with the receipt of monies into the vending machine, the return of monies from the vending machine, and allowing access to the contents of the vending machine, said microprocessor further for data communication with a currency totalizer associated with monies delivered into the vending machine, and an electrical erasable programmable read-only memory (EEPROM) device connected to said microprocessor and adapted to receive and retain a second program code operating with said first program code to operate said vending machine, wherein said second program code and data in said EEPROM device may be erased and reprogrammed with a third program code and data distinct from second program code and data previously programmed in said EEPROM device.
Patent CA-2342219-A1 (CA)
Title: Aqueous alkaline cyanide-free bath for the galvanic deposition of zinc or zinc alloy coatings
Inventor: JAMES BARRIE SYDNEY
IPC: C25D3/56
Filed: 1999-07-26
Abstract: An aqueous alkaline cyanide-free bath for the galvanic deposition of zinc or zinc alloy coatings on substrate surfaces is described, which contains in addition to a source of zinc ions and optionally a source of further metal ions, also hydroxide ions and a polymer of the general formula A that is soluble in the bath (see formula A) as well as optionally conventional additives. The bath may furthermore contain a quaternary derivative of a pyridine-3-carboxylic acid of the formula B and/or a quaternary derivative of a pyridine-3-carboxylic acid of the formula C     (see formula C) A process for the galvanic deposition of zinc coatings and zinc alloy coatings using the aforedescribed bath is also described.     By using the baths according to the invention it is possible to produce coatings that exhibit a uniform layer thickness combined with a high gloss, and which do not exhibit any tendency to exfoliate.
Patent CA-2343853-A1 (CA)
Title: Semiconductor device, ink tank provided with such semiconductor device, ink jet cartridge, ink jet recording apparatus, method for manufacturing such semiconductor device, and communication system, method for controlling pressure, memory element, security system of ink jet recording apparatus
Inventor: IMANAKA YOSHIYUKI
IPC: B41J29/393
Filed: 2001-04-11
Abstract: A solid type semiconductor device comprises energy converting means for converting energy from outside, and operating means operated by energy converted by the energy converting means. The energy converting means converts the electromotive force supplied from the outside to the device in non-contact into electric power. The operating means comprises information acquiring means actuated by electric power obtained by energy converting means; discriminating means; information accumulating means; and information communicating means.