baber/WOPTO huggingface dataset:
Patent PT-1478662-E (PT)
Title: Method for producing hypoallergenic major birch pollen allergens rbet v 1
Inventor: CROMWELL OLIVER
IPC: A61K39/36
Filed: 2003-02-07
Abstract: The invention relates to a process for the preparation of hypoallergenic major birch pollen allergens by means of one or more chromatographic purification steps using essentially unbuffered aqueous bases as eluent and subsequent neutralization. The hypoallergenic major birch pollen allergens are distinguished by a lack of, but at least by reduced immunoglobulin E binding with simultaneous retention of therapeutically relevant T-cell stimulation. They can therefore be employed as low-side-effect therapeutic agents for specific immunotherapy.
Patent PT-1490444-E (PT)
Title: Method of fixing macro-objects to an electricity conducting- or semi-conducting-surface by means of electrografting, surfaces thus obtained and applications thereof
Inventor: DENIAU GUY
IPC: C25D13/06
Filed: 2003-03-19
Abstract: The invention relates to a method of fixing macro-objects to an electricity conducting- or semi-conducting surface by means of electrografting. The invention also relates to the electricity conducting- or semi-conducting-surfaces obtained using the aforementioned method and to the applications of same.
Patent PT-1607090-E (PT)
Title: Asimadoline for the treatment of irritable bowel syndrome
Inventor: GOTTSCHLICH RUDOLF
IPC: C07B35/02
Filed: 1999-04-16
Abstract: Production of N-methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidino) ethyl]-2,2-diphenylacetamide (Ia) or N-methyl-N-[(1R)-1-phenyl-2-((3R )-3-hydroxypyrrolidino)ethyl]-2,2-diphenylacetamide (Ib) comprises (a) reacting the corresponding enantiomer of an N-substituted phenylglycine derivative with an optionally O-protected 3-hydroxypyrrolidine derivative, (b) reducing the product to convert the N-substituent to methyl and remove any protecting group, and (c) reacting with an activated diphenylacetic acid derivative. Production of N-methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidino) ethyl]-2,2-diphenylacetamide (Ia) or N-methyl-N-[(1R)-1-phenyl-2-((3R )-3-hydroxypyrrolidino)ethyl]-2,2-diphenylacetamide (Ib) comprises (a) reacting the corresponding enantiomer of an N-substituted phenylglycine derivative of formula (II) with an optionally O-protected 3-hydroxypyrrolidine derivative of formula (III), (b) reducing the product of formula (IV), and (c) reacting the product of formula (V) with an activated diphenylacetic acid derivative of formula (VI) to give a product of formula (Ia/Ib): [Image] [Image] [Image] [Image] R : H, OR1> or SR1>; R1>A, aryl, heteroaryl, Si(R3>)3 or COR3>; R3>H, A, aryl or heteroaryl; A : 1-6C alkyl; M : H, alkali(ne earth) metal, NH4 or alkylammonium; R2>H, A, aryl, heteroaryl, Si(R3>)3 or COR3>; R4>halogen, OA or OCOA. An independent claim is also included for compounds referred to as N-methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidino)ethane] and N-methyl-N-[(1R)-1-phenyl-2-((3R)-3-hydroxypyrrolidino)ethane] useful as intermediates for (Ia) and (Ib). - ACTIVITY : Antiinflammatory; analgesic; diuretic. - MECHANISM OF ACTION : None given.
Patent PT-1730432-E (PT)
Title: Fail-safe circuit for gas valves
Inventor: VEGTER DERK
IPC: F16K31/00
Filed: 2005-03-17
Abstract: A fail-safe circuit for gas valve, has at least one input (11) connected to a control device and at least one output (12,13) connected to a gas valve, in which the fail-safe circuit (10) prepares an output voltage at those outputs for opening a gas valve, when at the output (11) of the fail-safe circuit (10) an input is provided from the control device and has at least two different time-sequential frequency signals.
Patent PT-1968963-E (PT)
Title: Substituted propiolic acid amides and their use for producing analgesics
Inventor: HAURAND MICHAEL
IPC: A61K31/41
Filed: 2006-12-22
Abstract: Propiolic acid amides (I), optionally as pure stereoisomers, particularly enantiomers or diastereomers, including racemates and mixtures in any proportion, also salts and solvates, are new. Propiolic acid amides of formula A-N(R 1>)-(CR 2>R 3>) a-(CR 4>R 5>) b-(CR 6>R 7>) c-NR 8>-CO-Ctriple boundC-R 9> (I), optionally as pure stereoisomers, particularly enantiomers or diastereomers, including racemates and mixtures in any proportion, also salts and solvates, are new a, b and c : 0 or 1, totaling 1-3; A : particular heterocyclic groups; R 1>-R 8>hydrogen or various substituents Full definitions are given in the DEFINITIONS -Full Definitions field. An independent claim is included for several methods for preparing (I). ACTIVITY : Analgesic; Antimigraine; Antidepressant; Nootropic; Neuroprotective; Antiparkinsonian; Anticonvulsant; Tranquilizer; Antitussive; Uropathic; Antidiarrheal; Antipruritic; Antiasthma; Cerebroprotective; Ophthalmological; Antialcoholic; Antismoking. MECHANISM OF ACTION : Regulation, particularly inhibition, of the mGluR5 receptor. The compound 1-(3-phenylpropiolyl)-4-(thiophen-3-yl)-piperazine has IC50 against the porcine mGluR5 receptor of 1.89 mu M.
Patent PT-1934353-E (PT)
Title: Il-15r alpha sushi domains as a selective and potent enahncer of il-15 action though il-15rbeta/gamma , in hyperagonist il-15 ralpha sushi -il 15 fusion proteins .
Inventor: JACQUES YANNICK
IPC: C07K14/54
Filed: 2006-10-06
Abstract: The present invention relates to the stimulation of the IL-15Rbeta/gamma signalling pathway, to thereby induce and/or stimulate the activation and/or proliferation of IL-15Rbeta/gamma-positive cells, such as NK and/or T cells.Appropriate compounds include compounds comprising at least one IL-15Rbeta/gamma binding entity, directly or indirectly linked by covalence to at least one polypeptide which contains the sushi domain of the extracellular region of an IL-15Ralpha.
Patent PT-2122959-E (PT)
Title: Subcarrier spacing identification
Inventor: LINDOFF BENGT
IPC: H04L27/00
Filed: 2008-01-28
Abstract: A cellular communications system that utilizes OFDM in its radio interface is capable of utilizing either a first subcarrier spacing or a second subcarrier spacing. Which of these is presently in use is indicated by generating a first type of synchronization signal in response to the first subcarrier spacing presently being in use, and generating a second type of synchronization signal in response to the second subcarrier spacing presently being in use. Whichever of the first type of synchronization signal and the second type of synchronization signal was generated is transmitted. To distinguish between the first and second types of synchronization signals, a time domain representation of the second type of synchronization signal includes a plurality of instances of the first type of synchronization signal.
Patent PT-2486803-E (PT)
Title: Liquid, heat gellable food
Inventor: HEUVELMAN LAMBERTUS
IPC: A21D13/00
Filed: 2012-02-13
Abstract: This invention relates to a liquid, heat gellable food, to a method for the preparation of this liquid food, and to the use thereof in pastry, desserts, and the like.  The liquid, heat gellable food of the invention comprises a denatured, non-coagulated whey protein and an edible base, and is especially suitable as a pie filling. When the liquid, heat gellable food is heated during the end application, such as baking in the oven, the structure of the liquid food becomes firm due to gelling and stays firm when cooled down and stored. Furthermore, the food of the invention has a long shelf-life.
Patent PT-696288-E (PT)
Inventor: TURSKI LECHOSLAW
IPC: C07F9/6509
Filed: 1994-04-28
Abstract: Quinoxalinedione derivs. of formula (I) and their isomers and salts, are new. R<1> = (CH2)nCR<2>H(CH2)m-Z; R<5>-R<8> = H, T, CF3, NO2, halo, NR<9>R<10>, CN, SOPR<11>, SO2NR<12>R<13>, SO3H, SO3T or OR<14>; T = 1-6C alkyl; R<2> = H or (CH2)qR<3>; R<3> = H, OH, OT or NR<15>R<16>; r,m,q = 0, 1, 2 or 3; Z = POXY, OPOXY, OR<17>, NR<18>R<19>, NHCOR<20>, NHSO2R<21>, SO2R<22>, CO2R<23>, halo, CN or tetrazolyl; R<11> = H, T or phenyl; p = 0, 1 or 2; R<12>, R<13>, R<17>, R<23> = H or Q; Q = 1-4C alkyl; R<14> = H, or Q; Q = 1-4C alkyl; R<14> = H, or Q (opt. substd. by 1-3 halo); R<20>, R<21> = T, phenyl (opt. substd. by halo), or heteroaryl; R<22> = HO, TO or NR<24>R<25>; X,Y = OH, TO, Q or NR<18>R<19>; R<9>,R<10> = H, COT, phenyl, or T (opt. substd. by QO, NH2, NHQ or N(Q)2); or NR<9>R<10> = a 5-7 membered satd. heterocycle (which contains one other N, O or S atom and which is opt. substd.), or an unsatd. 5-membered heterocycle (which contains 1-3N atoms and which is opt. substd.); R<15>, R<16>,R<18>,R<19> = H, Q or phenyl; or NR<15>R<16> and/or NR<18>R<19> = a gp. as NR<9>R<10>; R<24>, R<25> = H or Q; or NR<24>R<25> = a satd. 5-7 membered heterocycle (which contains one other S, O or N atom and which is opt. substd.). Provided that (a) when R<2> is H and Z is CO2R<23> or POXY, then R<5>-R<8> are not H; (b) when R<2> is H, Z is POXY or CO2R<23> and R<5>, R<6>, R<7> or R<8> is CF3, NO2, NH2, halo or Me, the cpds. (I) are disubstituted.; (c) when R<1> is methanephosphonic acid and R<6> is CN or substd. imidazolyl, then R<5>, R<7> and R<8> cannot all be H; (d) when R<1> is methanephosphonic acid, R<6> is CF3 or NO2 and R<7> is imidazolyl, then R<5> and R<8> cannot both be H; and (e) when R<1> is CH2COOH and R<5> and R<8> are H, then R<6> and R<7> cannot both be halo or Me.
Patent PT-758231-E (PT)
Inventor: HAGER JORG-CHRISTIAN
IPC: A61K31/38
Filed: 1995-04-24
Abstract: This invention relates to a pharmaceutical composition comprising as active principle, docetaxel or a taxoid derived from docetaxel, one or more unsaturated phospholipids and a small amount of one or more negative phospholipids, allow the active principle to be formulated in high concentration and are suitable for administration by injection.
Patent PT-912267-E (PT)
Inventor: STELZL THOMAS
IPC: B23K26/00
Filed: 1996-05-29
Abstract: In an arrangement for producing expanded material (8), in particular from foil-type webs (2) of metal, with a cutting device (3) for producing coherent strips of webs (5) of foil, and with an expanding device (6, 7) for expanding the web (5), the cutting device (3) comprises laser beam, water jet or electron beam (4)-emitting devices which are arranged substantially adjacent each other, transversely to the moving direction of the web (2), and which are controlled by a controlling device.
Patent PT-868713-E (PT)
Inventor: SOUPARIS HUGUES
IPC: G09F3/02
Filed: 1996-10-22
Abstract: The invention relates to a security marking label for a transparent support such as the windshield of a motor vehicle. The label comprises information specific to the marked support. The label is comprised of a complex formed of two superimposed elements between which is interleaved a marking element, at least one of said elements having a layer appropriate to provide for the binding of the transparent support and at least one of said elements comprising a diffraction network.
Patent PT-885240-E (PT)
Inventor: FORTE LUIGI
IPC: C07J71/00
Filed: 1996-12-04
Abstract: Process for preparing the compound 11beta-21-dihydroxy-2'-methyl-5'betaH-pregna-1,4-dieno[17,16-d]oxazoline-3,20-dione of formula (I):which comprises adsorbing said compound, contained into an aqueous solution resulting from fermentation broths or process streams, on an adsorbent polymeric resin having a styrenic or acrylic matrix and subsequently desorbing the said compound by eluting the resin with suitable mixture of water with a water-miscible organic solvent.
Patent PT-790358-E (PT)
Inventor: NEUGART HORST
IPC: E03C1/06
Filed: 1995-08-11
Abstract: The pivot provides an attachment point for a shower spray jet which can be pivoted about a point (Y). The attachment point (16) is mounted on the end of an arm (2) which can be moved up or down along a vertical rod (1). The spray jet can pivot to any angular position in which it is retained by a brake pad (18), which is spring loaded against a disc on the jet pivot point. The pad has serrations (18b) which engage with serrations on the disc. The brake pad can be released from the disc with a finger operated lever (16).
Patent PT-808898-E (PT)
Inventor: UHLMANN EUGEN
IPC: C12N9/00
Filed: 1997-05-12
Abstract: The invention relates to enzymatic RNA molecules which cleave mutant N-ras mRNA, preferably at a NUX cleavage site (N = any base, X = A, C or U), having preferably the sequences  5'-CCAACACCUGAUGAGCGUUAGCGAAACCUGCU-3' or  5'-UCCCAACCUGAUGAGCGUUAGCGAAACACCUG-3', modified derivatives thereof, pharmaceuticals containing such molecules and use of such molecules for the preparation of pharmaceuticals for the treatment of diseases involving abnormal cell growth and/or differentiation. <IMAGE>
Patent PT-849949-E (PT)
Inventor: FABRIZI FABRIZIO
IPC: H04N7/18
Filed: 1997-12-16
Abstract: A scheme for assembling the external stations of intercom and video-intercom systems, comprising a series of modular positioning frames (3A-3C), which are fixed either to a series of flush-mounting modular boxes (2A-2C) or to a series of containers applied directly to the surface of a wall (11) and which determine the positioning of a series of functional modules (7A-7L) for analog and/or digital systems. PLastic or aluminium modular faceplates (5A-5H; 6A-6T) are provided for covering the front surface of each functional module (7A-7L), or one-piece steel faceplates for covering the entire external station, these comprising control and/or indicating means for the respective module (7A-7L). <IMAGE>
Patent PT-923942-E (PT)
Inventor: USUI FUSAO
IPC: A61K9/26
Filed: 1997-02-04
Abstract: Providing a formulation of a 5 alpha -reductase inhibitor for oral administration. ÄMeans for SolutionÜ   A formulation of a 5 alpha -reductase inhibitor for oral administration, which comprises a composition obtained by grinding a mixture of an azasteroid, a water-soluble polymer and a disintegrant.
Patent PT-887347-E (PT)
Inventor: HERBERT TANNER DR
IPC: C07D339/04
Filed: 1998-06-10
Abstract: Production of dry thioctic acid (I) comprises treatment of crude material enriched in (I) with liquid or super-critical CO2. Also claimed is (I) with a cyclohexane content of 20 ppm or below.
Patent PT-1012286-E (PT)
Title: Allelic variant of human stat3
Inventor: SERLUPI-CRESCENZI OTTAVIANO
IPC: C12N1/21
Filed: 1998-09-15
Abstract: A predominant allelic variant of the human STAT3 protein, the cDNA sequence encoding it, its use in therapy and/or in diagnosis of autoimmune and/or inflammatory diseases, as well as pharmaceutical compositions comprising it.
Patent PT-1005004-E (PT)
Inventor: GARRO GIUSEPPE
IPC: G08B15/00
Filed: 1999-06-25
Abstract: A tubular structure (1) in which to hold a plurality of anti-intrusion devices (6, 7, 8, 9) comprising a lining (15) in a material that is opaque to the eye but transparent to infrared rays, micro-wave and video filming in the field of infrared in order to completely hide the lined part . <IMAGE>
Patent PT-1018614-E (PT)
Inventor: MONTERDE FABREGAT LUIS
IPC: F16K5/04
Filed: 1999-12-23
Abstract: The valve for fluids comprises a tubular body (1') that has a radial branch (5') and in whose inside acts a control spindle (7) with an external control handle (42). The valve is characterized in that the control spindle (7) is fitted with a composite seal (18) formed by two O-rings (19,20) connected to each other by two also O-shaped, diametrically opposed lengths (21,22) in such a way that the O-rings (19,20) obstruct, between the control spindle (7) and the tubular body (5'), the coaxial passage of the fluid, and the O-shaped lengths (21,22) obstruct the passage of the fluid in a transversal, i.e. peripheral direction. Also characteristic is the fact that the control spindle (7) is cylindrical and has two peripheral grooves (14,15) connected to each other by another to diametrically opposed grooves, the composite seal (18) being fitted into said set of grooves.
Patent PT-1062463-E (PT)
Inventor: KRECKE EDMOND D
IPC: F24F5/00
Filed: 1999-03-09
Abstract: A method of air-conditioning a building with low heat loss, having the following steps: providing a fresh-air/outgoing-air system for feeding fresh air through a heat accumulator being located beneath said building and extracting said outgoing air through the heat accumulator; routing the fresh-air and the outgoing air in first and second tubes, where the first tubes are nested in the second tubes so as to recover heat energy present in the outgoing air.
Patent SG-91984-G (SG)
Title: Binding locker
IPC: B65D63/12
Filed: 1984-12-27
Abstract: A binding locker is disclosed including a band having a rack of teeth thereon and a socket having a hole for receiving a leading end of the band. A locking member having a plurality of locking teeth thereon is disposed within the socket's hole so that the locking teeth mesh with the engaging teeth of the rack to thereby tie the socket and band together thus binding a plurality of objects such as wires together. The socket hole has a curved surface disposed to face or oppose the locking member and for receiving a mating, oppositely curved surface of the band. Further, the locking member is connected to the socket to be rotatable within the hole and further, has a projection extending oppositely of its locking teeth. An opening is disposed within the socket at substantially right angles with the axis of the socket hole to receive the projection of the locking member. Further, the band has a pair of ribs extending lengthwise therealong between which the rack of teeth extend.
Patent SG-173194-G (SG)
Title: Process for the preparation of high-purity tetrahydrofuran
Inventor: FALLING STEPHEN NEAL
IPC: C07B61/00
Filed: 1994-12-06
Abstract: Disclosed is a process for the preparation of high-purity tetrahydrofuran from a mixture of 2,5-dihydrofuran and 3,4-epoxy-1-butene and/or crotonaldehyde wherein the mixture is hydrogenated in the presence of a nickel or platinum catalyst to obtain a product consisting essentially of tetrahydrofuran and 1-butanol which are readily separable.
Patent IE-33921-L (IE)
Title: Welding steel rods to form mesh.
IPC: B23K11/00
Filed: 1970-01-14
Abstract: 1,251,781. Welding by pressure. BAUSTAHLGEWEBE G.m.b.H. 5 Jan., 1970 [15 Jan., 1969], No. 412/70. Heading B3R. In making steel rod mesh, pressure exerted on the rods is maintained approximately constant during weld penetration and thereafter is increased. A mesh-welding machine (Fig. 1) having upper and lower electrode arrays 2, 3 in which the upper array is movable vertically towards and away from the lower array to effect welding, includes a cam disc 14 rotatable with a shaft 15 and in engagement with a roller 12 on a rocker arm 10 which has one end pivoted to a drawbar 23 adjustably connected to a mechanism movable with the upper array 2. Each lower electrode is supported by an adjustable compression spring 5. The draw-bar 23 is adjustably connected to the mechanism movable with the upper electrode array whereby the initial gap between the upper and lower arrays can be set. The adjustment means comprise a hand wheel 36 and locking lever (46) (Fig. 2, not shown) for operating a screw and worm mechanism 25, 26 to vary the length of draw-bar 23 effective between the upper and lower arrays. A guide tube 50 with a funnel-mouth is provided to ensure correct insertion and alignment of longitudinal rods 45. The tube is pivoted to the frame at 51 and supported adjacent the electrodes by a spring biased bearing 52. The cam disc 14 (Fig. 3) has consecutive sectors I to IV whose radii with reference to a point M are: sector I-radius constant, r; sector II-radius varies between r and r+h; sector III-radius varies between r+h and r+h<SP>1</SP>, where h<SP>1</SP>=h+x; sector IV-radius varies between r+h<SP>1</SP> and r. In operation the cam disc 14 rotates in contact with roller 12 in such a direction as to bring sectors I-IV into contact with the roller sucessively in that order. Hence, contact of sector I with roller 12 results in no movement of upper electrode array 2; contact of sector II with roller 12 results in downward vertical movement of array 2 to exert pressure on the rods 44, 45 to be welded, welding commencing at contact of point C (the juncture of sectors II and III), with roller 12; contact of sector III with roller 12 results in an increased pressure being exerted on the rods, welding continuing to the time when point D of sector III contacts roller 12, whereby, due to local fusion at the weld points, the rods actually experience an approximately constant pressure, and, after cessation of welding, experience an increase of pressure up to the time when point E (the juncture of sectors III and IV), contacts roller 12; and contact of sector IV with roller 12 results in a decrease in pressure and, finally, upward movement of the upper electrodes. In modifications the cam disc may have only three sectors (Fig. 4, not shown), the constant radius sector being omitted; and the electrodes, instead of the lower ones, may be supported by compression springs (Figs. 7, 8, not shown).
[GB1251781A]
Patent CU-20629-L (CU)
Title: Maquina y procedimiento para el llenado distribucion e  hilerado de bolsas en el campo
Inventor: GANCHEV IVAN
IPC: B65B1/06
Filed: 1972-09-28
Abstract: Acoplada integralmente a un chasis porta-aperos y destinada a llenar bolsas de polietileno y otros materiales con tierra. La máquina toma la tierra derectamente del campo y mediante un sistema mecánico llena las bolsas con la misma y las deposita en el suelo, permaneciendo estas verticalmente. Las bolsas son suministradas al sistema mecánico de la máquina por cuatro obreros, los cuales van sentados sobre la misma.
Patent IE-37173-L (IE)
Title: Oxidation of iron chloride
IPC: C01G49/00
Filed: 1973-02-01
Abstract: 1363831 Oxidation of Fe chloride E I DU PONT DE NEMOURS & CO 9 Feb 1973 [9 Feb 1972] 6472/73 Heading C1A Fe oxide and Cl2 are produced by passing O2 and Fe chloride upwardly through a reaction area divided into at least two vertically adjacent cones each separated from the next by a foraminous member, and maintaining a concurrent flow of inert solid particles through the reaction area. The chloride may be FeCl3 or FeCl2 and may be fed in powder form and then vaporized. The reaction area is maintained at 400- 1000 C. The solid particles may be sand, SiO2, Al2O3, TiO2 or Fe oxide, and are preferably recycled.
[GB1363831A]
Patent IE-31865-L (IE)
Title: Pneumatic tyre for aircraft
IPC: B60C11/24
Filed: 1968-04-08
Abstract: 1,222,964. Pneumatic tyres. DUNLOP CO. Ltd. 5 April, 1968 [8 April, 1967], No. 16197/67. Heading B7C. The tread of a pneumatic tyre is provided with recesses 1 each having at least one face to be engaged by water standing on a surface over which the tyre is to run under load and water outlets 3 associated with at least some of the recesses to promote the flow of water through the recesses and against the faces to effect a hydrodynamic action which tends to decrease the speed of the tread relative to the water-covered surface during slipping of the loaded tyre upon the wet surface. The recesses 1 may taper in depth or may be in the form of cylindrical or cubic holes. The water outlets 3 may be in the form of conduits, as shown, or grooves, Figs. 2, 3 (not shown). The face(s) of the recesses upon which the water impinges may be plane or concave. The outlets 3 may be arranged circumferentially, transversely, inclined to or away from the normal direction of rotation of the tyre and/or inclined radially. They may also extend transversely into a circumferential groove and/or to a shoulder or circumferentially between adjacent recesses.
[GB1222964A]