baber/WOPTO huggingface dataset:
Patent EP-0868146-B1 (EP)
Inventor: WEBSTER WILTON JR
IPC: A61B5/296
Filed: 1996-10-04
Granted: 2004-02-25
Abstract: An electrode catheter for cardiac electrophysiology. An elongated body suitable for intravascular insertion surrounds a plurality of electrode lead wires. A composite electrode comprises a plurality of tip electrodes and defines a margin along a proximal edge. Each tip electrode is electrically connected to an associated electrode lead wire and is adjacent to another tip electrode on at least one side along an axis of the elongated body. Each tip electrode is separated from the another tip electrode by insulation. A cup electrode is electrically connected to an associated electrode lead wire and defines a cavity shaped to overlap the margin of the composite electrode. The cup electrode is fixedly secured to the composite electrode and to a distal end of the elongated body and is separated from the composite electrode by insulation.
Patent EP-0865391-B1 (EP)
Inventor: DRURY TIMOTHY
IPC: B65D77/00
Filed: 1996-11-15
Granted: 2001-03-14
Abstract: An infusion packet comprises a pair of sealed compartments (12a, 12b) containing infusion material and joined together at opposite ends of the packet. A drawstring (14) attached intermediate its length to a connecting region (8) between the two compartments at one said end has pull portions extending between the compartments from said attachment and held movably at the opposite end of the packet, whereby said pull portions can be drawn apart to contract the packet. To produce the packet the compartments are initially formed end to end, joined by the connecting region. An intermediate portion (16) of the drawstring is attached to the connecting region before the compartments are doubled over to bring their opposite ends together with drawstring pull portions between them. Said opposite ends are then secured together in a manner permitting movement of the drawstring pull portions between them to contract the packet.
Patent EP-0870041-B1 (EP)
Inventor: KEATING MARK T
IPC: C07K16/18
Filed: 1996-12-20
Granted: 2007-01-24
Abstract: One aspect of the invention relates to the identification of the molecular basis of long QT syndrome. More specifically, the invention has identified that mutated KVLQT1 causes long QT syndrome. The analysis of this gene will provide an early diagnosis of subjects with long QT syndrome. The diagnostic methods comprise analyzing the nucleic acid sequence of the KVLQT1 gene of an individual to be tested and comparing them with the nucleic acid sequence of the native, non-variant gene. Alternatively, the amino acid sequence of KVLQT1 may be analyzed for mutations which cause long QT syndrome. Presymptomatic diagnosis of long QT syndrome will enable practitioners to treat this disorder using existing medical therapy. A second aspect of the invention relates to the realization that KVLQT1 coassembles with minK to form a cardiac potassium channel.; This allows one to assay for drugs which interact with this channel to identify new drugs which are useful for treating or preventing long QT.
Patent EP-0791329-B1 (EP)
Inventor: TAYLOR CHARLES S
IPC: A61B17/02
Filed: 1997-02-20
Granted: 2003-04-23
Abstract: The invention is devices and techniques which use a negative (suction) pressure or vacuum, applied through a surgical instrument, to fix the position of a portion of the surface of a beating heart so that a surgical procedure can be more easily performed. The devices apply a negative pressure at several points on the outer surface of the heart such that a portion of the heart is fixed in place by the suction imposed through the surgical instrument. Because the instrument fixes the position of the tissue, and because the instruments remain at a constant distance from the particular portion of the heart where the surgery is being performed, the device may also serve as a support or platform so that other surgical instruments or devices can be advantageously used at the site. In certain preferred embodiments, the devices described herein have structures to facilitate the use of additional surgical instruments such that the placement of negative pressure device permit the surgeon to advantageously manipulate the other instruments during surgery. The negative pressure is preferably imposed through a plurality of ports which may be disposed in a substantially planar surface of the instrument which contacts the cardiac tissue. <IMAGE>
Patent EP-0798003-B1 (EP)
Inventor: SAVAGE MAGARET
IPC: C12N7/04
Filed: 1997-03-10
Granted: 2006-05-31
Abstract: A method of reducing the titer of viruses in a solution of biologically active proteins without adversely affecting the activity of the protein, the method comprising the step of passing the solution at a pH ranging from about 5.0 to about 7.0 through a structured depth filter comprising a positively charged porous filter element, the average pore diameter of the filter element being larger than the average diameter of the viruses and the filtration being done under conditions resulting in a substantial reduction in virus titer in the filtered solution while retaining biological activity of the proteins.
Patent EP-0803244-B1 (EP)
Inventor: GERS-BARLAG HEINRICH DR
IPC: A61Q17/04
Filed: 1997-04-15
Granted: 2003-07-09
Abstract: The use of mono- and/or di-esters (B) of a branched 10-24C alkane carboxylic acid with di- or tri-glycerol is claimed as solvent, solvent aid or solubiliser for 4,4',4"-(1,3,5-triazin-2,4,6-triyltriimino) tris-benzoic acid-tris-(2-ethylhexyl ester) (A). Also claimed is a light-protective combination of (A) and one or more (B)
Patent EP-0885200-B1 (EP)
Inventor: GESING ERNST RUDOLF F
IPC: C07D251/16
Filed: 1997-02-20
Granted: 2008-05-21
Abstract: L'invention concerne de nouvelles arylsulfonyl(thio)urées substituées de formule (I) et leurs sels. Dans la formule, A désigne azote ou un groupe CH; Q désigne oxygène ou soufre; R1 désigne hydrogène, halogène ou l'un des radicaux suivants éventuellement substitués: alkyle, alcoxy, alkylthio, alkylamino, dialkylamino, cycloalkyle, cycloalkyloxy ou hétérocyclyloxy; R2 désigne hydrogène, halogène ou l'un des radicaux suivants éventuellement substitués: alkyle, alcoxy, alkylthio, alkylamino, dialkylamino, cycloalkyle, cycloalkyloxy ou hétérocyclyloxy; R3 désigne hydrogène ou alkyle le cas échéant substitué; R4 désigne alkyle, alcoxy, alcényle, alcinyle, alcényloxy, alcinyloxy, cycloalkyle, cycloalkyloxy ou cycloalkylalkyle le cas échéant substitués; et R5 désigne hydrogène, formyle ou l'un des radicaux suivants: alkyle, alkylcarbonyle, alcoxycarbonyle, alkylsulfonyle, alcényle, alcinyle, cycloalkyle, cycloalkylcarbonyle, cycloalkylsulfonyle ou hétérocyclyle. Le composé N-(4,6-diméthyl-pyrimidin-2yl)-N'-(2-(1,1,2,2-tétrafluoréthoxy)-6-méthyl-phénylsulfonyl)-urée est exclu. L'invention concerne également des procédés de préparation de ces nouveaux composés et leur utilisation comme herbicides.
Patent EP-0884981-B1 (EP)
Inventor: HAHN RAINER DR
IPC: A61C9/00
Filed: 1997-03-05
Granted: 2001-11-28
Abstract: The free edges of the tray walls (12,16,26) run so that together with soft tissue of the mouth of a patient they are able to form a sealing point. At least one impression material connecting component (30) connected to the tray interior is provided. A source for liquid hardenable impression material is connected to the impression material-connecting component. The tray ( has at least one vacuum connection component (32,34,36) connected to the tray interior, which is connected to a vacuum source. The vacuum source adjusts a pressure drop preferably in the range between 50 and 150 mbar.
Patent EP-0948338-B1 (EP)
Inventor: ESKELAND BJODNE
IPC: A61K35/54
Filed: 1997-11-18
Granted: 2002-07-31
Abstract: The utilization of an egg-based preparation as an antidepressant.
Patent EP-0910659-B1 (EP)
Inventor: WANG CHANG YI
IPC: A61K38/00
Filed: 1997-06-03
Granted: 2006-08-09
Abstract: This invention is directed to monoclonal antibodies produced by using CD4-expressing T lymphocytes, such as peripheral blood mononuclear T cells, thymocytes, splenocytes and leukemia or lymphoma derived T cell line cells such as HPB-ALL or SUP-T as the immunogen in accordance with the protocols and screening procedures described. The monoclonal antibodies of the present invention are characterized by their ability to neutralize in vitro and in vivo primary isolates of Human Immunodeficiency Virus (HIV) and related immunodeficiency viruses. The antibodies are directed against a host cell antigen complex comprising CD4 protein in association with domains from chemokine receptors and have broad neutralizing activities against primary isolates from all clades of HIV type 1 (HIV-1) and primary isolates of HIV type 2 (HIV-2) and Simian Immunodeficiency Virus (SIV). The present invention is also directed to a method of selecting and producing such antibodies, hybridomas which secrete such antibodies, pharmaceutical compositions comprising such antibodies and methods for pre- and post-exposure prevention of immunodeficiency virus infection in primates, including humans, by such antibodies whose primary targets are CD4-expressing lymphocytes.                                              00000
Patent EP-0932393-B1 (EP)
Inventor: BREITENBACH JOERG
IPC: C08J9/12
Filed: 1997-08-21
Granted: 2002-04-03
Abstract: PCT No. PCT/EP97/04550 Sec. 371 Date Mar. 1, 1999 Sec. 102(e) Date Mar. 1, 1999 PCT Filed Aug. 21, 1997 PCT Pub. No. WO98/09616 PCT Pub. Date Mar. 12, 1998Solid foamed active ingredient preparations based on melt-processable polymers, obtainable by extrusion of a melt of one or more polymers which comprises active ingredient and which is impregnated with a volatile, physiologically acceptable blowing agent and expanded.
Patent EP-0944973-B1 (EP)
Inventor: RUDOLPH DIETMAR
IPC: H04B1/12
Filed: 1997-11-03
Granted: 2004-12-29
Abstract: A method for the transmission of digital signals, particularly in the AM bands (broadcasting bands), with high-level modulation, preferably 32 APSK or 64 ASPK, being used for data blocks to be transmitted. At the receiving end, time-periodic measurements of a noise are carried out and noise signals determined therefrom are subtracted from received signals.
Patent EP-0943003-B1 (EP)
Inventor: COLEMAN MICHAEL
IPC: C12N15/85
Filed: 1997-12-01
Granted: 2004-11-17
Abstract: This invention relates to gene delivery and expression, including gene therapy, by using vectors which encode stable mRNA and methods of using such vectors. In particular, this invention relates to vectors which establish controlled expression of recombinant IGF-I genes within tissues at certain levels. The vector includes a 5' flanking region which includes necessary sequences for expression of a nucleic acid cassette, a 3' flanking region including a 3' UTR and/or 3' NCR, and a linker which connects the 5' flanking region to a nucleic acid sequence. The linker has a position for inserting a nucleic acid cassette. The linker does not contain the coding sequence of a gene that the linker is naturally associated with. The 3' flanking region is 3' to the position for inserting the nucleic acid cassette. The expression vectors of the present invention can also be regulated by a regulatory system and/or constructed with a coating.
Patent EP-0912794-B1 (EP)
Inventor: ANDERSSON ROINE
IPC: B01D29/25
Filed: 1997-12-22
Granted: 2002-11-27
Abstract: A cylindrical screen (16) comprises an inlet end (11) for receiving a paper pulp suspension to be separated from undesired particles, and a reject end (13) for removing separated particles. The screen (16) is intended for the kind of pressure screening apparatus having rotor wings (9) adapted to move along a cylindrical path close to the inlet side of the screen. Elongated flow deflecting members (22) are arranged on the inlet side of the screen and are distributed around the circumference of the screen, each elongated flow deflecting member extending obliquely relative to the centre axis of the screen and forwards relative to the direction of rotation of the rotor wings as seen from the inlet end (11) of the screen. According to the invention the distance between adjacent flow deflecting members (22) as seen in the circumferential direction of the screen is less than 6 mm, whereby a high efficiency is obtained with respect to separation of undesired particles without deteriorating the capacity.
Patent EP-1039869-B1 (EP)
Inventor: HODGETTS GRAHAM L
IPC: A61G7/10
Filed: 1997-12-16
Granted: 2011-02-23
Abstract: A patient transport system for transporting a patient from a bed to a stretcher or vice versa, using a bed sheet (80) and a conveyor (200) attached to the bed (10) or the stretcher. A first end of the sheet is removably attached to the conveyor and a second end of the sheet is free. The sheet is adapted to be positioned onto the patient supporting member of the bed or stretcher. The conveyor includes a roller (42) received by bearings (44). The roller can be removably received by the bearings. The roller can also include a telescopic arrangement so that its length can be adjusted. A pawl and ratchet assembly can be provided on the conveyor to prevent unwinding of the conveyor. The sheet is removably attached to the roller by adhesive tape or a clip (202) arrangement. A flexible belt (206) attaches the clip to the conveyor and is removably secured to the roller. The clip includes a body member (210) having a recess with a plug (212) received therein.
Patent EP-0884329-B1 (EP)
Inventor: CHAPMAN PAUL B
IPC: A61K47/48
Filed: 1990-05-25
Granted: 2003-06-25
Abstract: The present invention provides an anti-idiotypic monoclonal antibody which specifically induces an immune response against a glycosphingolipid. This invention also provides a composition of matter comprising an effective amount of a cytokine and a melanoma ganglioside-specific antibody attached to a carrier.
Patent EP-0902604-B1 (EP)
Inventor: WERNER WALTER DR
IPC: H05B41/40
Filed: 1998-09-03
Granted: 2002-12-18
Abstract: The lighting unit can be in the form of a free standing unit (1) and the main stem or pole can have an insert (7) that has a number of light sensitive sensors within in it. The sensors are distributed radially and respond to ambient light intensity. The sensors connect with a built in control module and this dims the electrical lighting unit (5) as the ambient lighting level increases.
Patent EP-0884814-B1 (EP)
Inventor: FONTANA RODOLFO
IPC: H02B1/21
Filed: 1998-05-12
Granted: 2009-01-14
Abstract: Modular adapter (1) for electrical devices (2), featuring a clamping device (31) for the connection to the bars (4) of a multiple-pole bar-based distribution system and a conductor (33) for the electrical connection of a device (2), such that the adapter (1) is symmetrical in relation to the axis (3) of its centre line, that the clamping device (31) is located on the side of the adapter facing the bars (4) with the connection axis (39) aligned with the axis (39') of the bar (4), that the side of the adapter (1) opposite the clamping device (31) features a seating (55) for receiving the electrical device (2) in a geometrical connection, and that the opposite edges (8) of the adapter (1) feature flanges (10) for fixing to a cabinet structure (7). <IMAGE>
Patent EP-0855389-B1 (EP)
Inventor: MARUYAMA TORU
IPC: A61P37/00
Filed: 1998-01-26
Granted: 2002-06-05
Abstract: A 3,7-dithiaprostanoic acid derivative of the formula (I) <CHEM> (wherein R<1> is OH, C1-4 alkoxy, NR<6>R<7> (wherein R<6>, R<7> are H, C1-4);R<2> is H, OH; R<3> is (i)alkyl, alkenyl, alkynyl (ii) phenyl, cycloalkyl (iii) alkyl, alkenyl, alkynyl substituted by phenyl, cycloalkyl (when R<2> is H, alkyl, alkenyl, alkynyl in (i) or (iii) may be substituted by OH) possesses a binding activity for PGE2 receptor (especially for EP4). Therefore they are useful for the treatment and/or prevention of immunologic diseases (autoimmune diseases, organ transplantation etc.), asthma, abnormal bone formation, neuronal cell death, liver damage, nephritis, hypertension, myocardiac ischemia etc.
Patent EP-0910899-B1 (EP)
Inventor: ARNOLD SIEGFRIED
IPC: G06K7/00
Filed: 1998-01-19
Granted: 2005-04-20
Abstract: In a transponder communication device (1) having a selector for the successive individual selection of transponders (2) the selector having interrogator (5) for generating at least one item of interrogation information (AFI) with which the transponders (2) can be interrogated to transmit answer information (AWI) in response to the interrogation information (AFI), and time-window generator (17) for generating a series of K successive time windows (ZF) and controller (20) for the time-window generator (17), which controller can activate the time-window generator (17) so as to generate the series F of K time windows (ZF) a number of times in succession, and evaluator (22) which cooperates with the time-window generator (17) and by which, depending on the occurrence of at least one item of answer information (AWI) transmitted to the transponder communication device (1) by a transponder (2) in response to interrogation information (AFI), a transponder (2) can be selected in at least one time window (ZF) in each series (F) of the series (F) of K time windows (ZF) generated a number of times in succession.
Patent EP-0954381-B1 (EP)
Title: Appareil de pulverisation de liquides et recipients et garnitures jetables utilisables avec celui-ci
Inventor: JOSEPH STEPHEN C P
IPC: B05B15/06
Filed: 1998-01-14
Granted: 2005-09-21
Abstract: Un pistolet pulvérisateur (1) comprend un réservoir (11) de liquide contenant une garniture amovible (13). La garniture (13), pouvant être thermoformée ou formée sous vide à partir d'une matière plastique, est un ajustage étroit à l'intérieur du réservoir et elle s'écrase à mesure que le liquide est extrait de l'intérieur de la garniture pendant le fonctionnement du pistolet. De préférence, la garniture présente une base comparativement rigide et est capable de se tenir, sans support, à l'extérieur du réservoir. Les parois latérales de la garniture sont de préférence minces par rapport à la base et elles peuvent se replier afin de jeter ladite garniture. Le réservoir (11) comprend un couvercle amovible (15) et est capable de se tenir en position renversée sur lui-même de manière à permettre son remplissage avec le liquide. Le couvercle (15) à également pour fonction de fixer la garniture (13) dans le réservoir et, à la fin de la pulvérisation, le couvercle (15) et la garniture (13) sont retirés ensemble du réservoir (11) et jetés, simplifiant ainsi le nettoyage du pistolet pulvérisateur.
Patent EP-0975878-B1 (EP)
Inventor: OESTERLE HELMUT
IPC: F16B23/00
Filed: 1998-02-16
Granted: 2003-05-21
Abstract: A screw (1) is provided with a shank (3), a head (2) and a boring part (5). The shank (3) is provided with a thread (4). The head (2) has a shoulder (6) disposed at an axial distance (B) from the bearing face (12), while a portion (7) adjoining the shoulder on the shank side is provided with a tool drive (8). The head (2) of the screw can therefore be seized in axially secure manner by a tool in the region of the shoulder (6), and this tool can then simultaneously transmit the necessary torque in the region of the tool drive (8) as well.
Patent EP-0926960-B1 (EP)
Inventor: EGOLF HEINZ
IPC: A42B3/08
Filed: 1998-05-14
Granted: 2000-11-29
Abstract: A helmet with an adjustable safety strap. The length of the strap used for securing the helmet can be adjusted by the wearer continuously, or progressively in stages of 1.5 mm, and fixed or released in any of the positions with only one hand, by way of a turn-lock fastener. The turn-lock fastener is rigidly incorporated in the helmet material and has cords which are guided from its two opposite sides along an inner side of the helmet to deflecting rollers, or deflecting points, on the helmet material, and then further guided therefrom along the strap to be tightened. The safety strap can be worn around the nape of the neck, or include a chin piece, among other manners of construction.
Patent EP-1003990-B1 (EP)
Inventor: BAXTER RANDY C
IPC: F02M63/00
Filed: 1998-06-12
Granted: 2009-04-08
Abstract: An electromagnetically actuatable disc-type valve includes a pre-assembled hydraulic sub-assembly with a core member and a separately pre-assembled electrical sub-assembly with a body. The exterior surface of the core member is configured to facilitate insertion into the electrical sub-assembly and orientation relative thereto by use of a bushing. The outside diameter of the body of the valve is no more than 13.5 millimeters in the vicinity of the delivery end of the hydraulic sub-assembly. A fluid filter is disposed between a tensioning spring and a calibration slide to facilitate more accurate flow checking and leakage checking of the valve during manufacture.
Patent EP-1045704-B1 (EP)
Inventor: COOK DAVID
IPC: A01N1/02
Filed: 1998-07-06
Granted: 2004-09-22
Abstract: Methods are provided for quenching undesired side reactions of pathogen inactivating compounds in biological materials comprising red blood cells. In a particular embodiment, methods are provided for quenching undesired side reactions of a pathogen inactivating compound that includes a functional group which is, or which is capable of forming, an electrophilic group. In this embodiment, the material is treated with the pathogen inactivating compound and a quencher, wherein the quencher comprises a nucleophilic functional group that is capable of covalently reacting with the electrophilic group. The electrophilic group on the pathogen inactivating compound is preferably a non-radical cationic group. In one embodiment, the pathogen inactivating compound includes a nucleic acid binding ligand and a mustard group, wherein the mustard group is capable of reacting in situ to form the electrophilic group. Preferred quenchers are thiols, such as glutathione. The methods permit inhibition of the modification of red blood cells in red blood cell containing materials during pathogen inactivation.
Patent EP-1007807-B1 (EP)
Inventor: BANTHIA NEMKURNAR
IPC: C04B14/48
Filed: 1998-07-16
Granted: 2002-10-02
Abstract: An improved reinforcing fiber for concrete is formed with two types of anchors positioned adjacent to each axial end of the fiber. A drag anchor which frictionally resist being pulled from the concrete without fiber breakage and a dead anchor between the drag anchor and adjacent axial end of the fiber, the dead end engages the concrete to develop stresses at a weakened point in the fiber formed between the drag anchor and its adjacent dead anchor to break the fiber or deform the dead anchor before maximum tensile strength of the fiber is reached so that the dead anchor functions to maximize the load carrying capacity while at the same time protecting against fiber rupture and the drag anchor continues to function after release of the weak point of the fiber.
Patent EP-1011896-B1 (EP)
Inventor: ARVEDI GIOVANNI
IPC: B22D11/04
Filed: 1998-07-29
Granted: 2002-01-16
Abstract: An improved mould for the continuous casting of steel slabs having thickness in the range from 50-120 mm, particularly suitable to be rolled to thin strips, presents two large faces (F), each one having in horizontal cross section a concave or rectilinear central zone symmetrical with respect to each other, connected at both sides to the narrow faces (f) through concave-convex wide bends with respect to the internal part of the mould, without other lengths being parallel to opposite portions of the other face (F), besides to a possible central rectilinear length. the radiuses of the concave portion (r1) and of the convex portion (r2) are in a mutual ratio of a range from 0.6 to 1.4, these portions being preferably the same at each horizontal cross section of the mould and increasing downwards, while the depth (a) of the concavity decreases downwards, being possibly constant from a height (ybc) to the outlet section, but being preferably continuously decreasing along the whole length of the mould, with a residual depth <=5 mm at the outlet zone.