baber/WOPTO huggingface dataset:
Patent DE-69427266-T2 (DE)
Inventor: MATSUO MASAAKI
IPC: A61P37/08
Filed: 1994-11-25
Granted: 2001-09-13
Abstract: A compound of the following general formula : <CHEM>  wherein   X   is carbonyl or sulfonyl; Y   is bond or lower alkylene; R<1>   is halogen, lower alkyl, halo(lower)alkyl, aryloxy, nitro or amino which may have 1 or 2 and same or different substituent(s) selected from lower alkyl, acyl and lower alkanesulfonyl; R<2>   is aryl or an aromatic hetero(mono- or bi-)cyclic group, and each of which may have 1, 2 or 3 suitable substituent(s); R<3>   is hydrogen or lower alkyl; R<4>   is   (i) a group of the formula -SO2-R<5> in which R<5> is lower alkyl or aryl optionally substituted with lower alkyl or lower alkoxy,   (ii) a group of the formula <CHEM> in which R<6> is aryl optionally substituted with lower alkyl or lower alkoxy, or   (iii) a group of the formula -A-(Z)p in which   A   is bond, lower alkylene, lower alkenylene or lower alkynylene, Z   is hydrogen, halogen, hydroxy, nitrile, amino, cyclo(lower)alkyl, aryl, aryloxy, acyl, acylamino, lower alkanesulfonylamino, arylsulfonylamino or an aromatic hetero(mono- or bi-)cyclic group, and each of the cyclic group may have 1, 2 or 3 suitable substituent(s), and p   is 1, 2 or 3; and     n   is 0, 1 or 2; provided that when n or p is more than 1, these R<1> and Z may be the same or different group respectively; or its pharmaceutically acceptable salt, processes for their preparation and pharmaceutical compositions comprising them.
Patent DE-69431800-T2 (DE)
Inventor: TAYLOR JOAN
IPC: A61K9/00
Filed: 1994-06-27
Granted: 2003-09-04
Abstract: There is disclosed a method for producing a system for delivering a drug for the treatment of a condition, comprising immobilizing a drug or other agent in a bio-compatible matrix containing at least one receptor for a physiological substance which will be in the environment of the matrix when administered, said receptor being anchored within the matrix but remaining biologically active being activated in response to the levels of said physiological substance to effect a conformational change in the matrix allowing mobilization and release of the drug only into the environment.
Patent DE-69432699-T2 (DE)
Inventor: VAHLENSIECK DR
IPC: C12N15/09
Filed: 1994-12-08
Granted: 2004-04-08
Abstract: The present invention discloses DNA molecules comprising a gene encoding yeast acetyl-coenzyme A carboxylase resistant to soraphen A inhibition. Mutations confering soraphen A resistance to acetyl-CoA carboxylase can be dominant or recessive, and they can be point mutations, deletion or insertion mutations. In addition methods of isolating a gene encoding fungal acetyl-coenzyme A carboxylase resistant to soraphen A inhibition are provided as well as methods for purifying fungal acetyl-coenzyme A carboxylase resistant to soraphen A inhibition. Purified enzyme can be used in assays to identify inhibitors of soraphen A resistant acetyl-coenzyme A carboxylase.
Patent DE-69433203-T2 (DE)
Inventor: IDE SATOSHI
IPC: C08G65/22
Filed: 1994-01-21
Granted: 2004-07-29
Abstract: A novel fluorinated hydrocarbon compound containing an oxygen or sulfur atom in its molecule, produced by the nucleophilic reaction of a fluorine compound with a hydrocarbon compound. This compound is useful as a lubricant for various applications and particularly excellent as an oil for refrigerators wherein hydrochlorofluorocarbon is used as the refrigerant and as a magnetic recording medium lubricant.
Patent DE-69500022-T2 (DE)
Inventor: LANGE SEBASTIEN
IPC: B61D3/12
Filed: 1995-03-15
Granted: 1996-12-19
Abstract: The system uses trucks which have a bogie at each end (6,6') and a covered platform (100,101) pivoted between the two ends which enable the ends of the trucks to be opened by running the bogies along parallel rail tracks (21,22) by means of points (23). Once the truck bogies are on the parallel rail tracks the open ends of the trucks lie at an angle to the tracks and they can be loaded/unloaded from either end using suitable road vehicles.
Patent DE-69503027-T2 (DE)
Inventor: LAVIEVILLE JEAN-PAUL
IPC: H02M7/48
Filed: 1995-12-28
Granted: 1998-11-26
Abstract: The multilevel convertor includes a voltage source (SE), a current source (C) and a succession of controlled switching cells (CL1,CL2...,CLn) each having switch pairs (T1,T`1,T2,T`2...,Tn,T`n) controlling the switching of capacitors (C1,C2...,Cn). The capacitors have nominally charge voltages proportional to their row in the convertor. The convertor has in parallel with the current source (C), a RLC filter circuit (CF). The filter circuit is designed to preferentially dissipate, at least in part, the energy of any component having a frequency included in a frequency band extending from the fundamental frequency of the voltage applied to the current source to a frequency equal to n times the convertor frequency, called the decoupling frequency, n is the number of convertor stages. These two frequencies, fundamental and decoupling, are not included in the frequency band.
Patent DE-69504340-T2 (DE)
Inventor: SAGET PIERRE LAURENT
IPC: B04B5/12
Filed: 1995-06-09
Granted: 1999-05-06
Abstract: Pollution separator and purifier apparatus (10) for at least one fluid mixture comprises: an inlet member (14) for admitting the fluid mixture to be treated into a stationary cylindrical body (12); a rotor mounted in the cylindrical body (12) and having a stack of at least two plates (18) with openings, cooperating with means that generate a pressure drop in the top portion of the apparatus and generating upward helical motion in the mixture to be treated; a hopper (22) for collecting the heavy phase, connected to the cylindrical body (12) beneath the rotor (16) and provided with forced evacuation means (24); and an extractor member (26) for extracting the treated mixture, and connected to the cylindrical body (12) above the rotor (16). The inlet member (14) is situated between the rotor (16) and the extractor member (26), and includes an annular chamber (28) connected to the annular gap (20) that exists between the periphery of the plates (18) and the wall of the cylindrical body (12), an inlet (30) for admitting the mixture to be treated into said annular chamber (28), and a central column (32). The apparatus includes means (26, 40, 42) for generating downward helical motion in the annular gap (20).
Patent DE-69508777-T2 (DE)
Inventor: COCKETT KEITH
IPC: C11D3/08
Filed: 1995-08-29
Granted: 1999-07-29
Abstract: PCT No. PCT/EP95/03396 Sec. 371 Date Apr. 13, 1998 Sec. 102(e) Date Apr. 13, 1998 PCT Filed Aug. 29, 1995 PCT Pub. No. WO96/09367 PCT Pub. Date Mar. 28, 1996Soluble alkali metal silicates combined with antiredeposition agents can actually have a beneficial effect on bleach stabilisation if said antiredeposition agents are intimately mixed with an alkali metal silicate solution, the resulting product being then dried (spray drying, turbo drying, etc . . . ) into granules.
Patent DE-69513890-T2 (DE)
Inventor: YONEZAWA KEITARO
IPC: F17C13/04
Filed: 1995-06-14
Granted: 2000-08-17
Abstract: A gas inlet (4), an inlet passage (8), a stop valve (7), an outlet passage (9) and a gas outlet (5) are communicated orderly with one another within a valve casing (3). The outlet passage (9) is communicated with the inlet passage (8) through a gas charging passage (10). A check valve (11) for blocking a flow from the inlet passage (8) to the outlet passage (9) is arranged in the gas charging passage (10). When a vacant gas cylinder (1) is charged with a high-pressure gas, the charge gas is supplied to a gas charging mouthpiece (17) connected to the gas outlet (5) while the stop valve (7) is kept closed. Thereupon, an interior space (A) of the gas cylinder (1) is charged with the charge gas from the outlet (5) through the check valve (11) and the gas inlet (4) in order. <IMAGE>
Patent DE-69514708-T2 (DE)
Inventor: DEMUS DIETRICH
IPC: C09K19/02
Filed: 1995-04-13
Granted: 2000-07-20
Abstract: A nematic liquid crystal composition having a low viscosity comprises a blend of of components Y1 and Y2, each composed of at least one compound, which nematic composition does not form a complex, and is characterized in that components Y1 and Y2 have a large difference between their respective heats of vaporization.
Patent DE-69528614-T2 (DE)
Inventor: VERHEIJEN JOHAN HENDRIKUS
IPC: C12Q1/37
Filed: 1995-07-06
Granted: 2003-06-18
Abstract: Detection or determination of a protease in a sample by incubating the sample with a substrate of the protease and observing proteolytic cleavage of said substrate. The substrate is a modified proenzyme containing a recognition site, e.g., an activation site, cleavable by said protease. Proteolytic cleavage of the modified proenzyme is detected by observing the resulting activity using a suitable substrate of the activated proenzyme. The protease may be e.g. an aspartic protease or a metalloprotease, and the modified proenzyme e.g. pro-urokinase having a mutant activation site which is cleavable by the protease to be determined.
Patent DE-69529513-T2 (DE)
Inventor: TAKEUTI ISAMU
IPC: B22D11/16
Filed: 1995-07-27
Granted: 2003-11-20
Abstract: The invention relates to a continuous casting method and a continuous casting apparatus, in which a non-solidifying cast piece is appropriately subjected to rolling by rolls while being continuously drawn by support rolls. According to this method, a non-solidifying rolling strain and a bulging strain are reduced whereby a total accumulated strain is suppressed to be made small, and thin cast pieces free of internal crack can be manufactured even in non-solidifying rolling under the condition of high speed casting. In the apparatus, a misalignment strain is suppressed and non-solidifying rolling of cast pieces is easily performed, and modification to thickness of cast pieces can be carried out without stopping the apparatus during operation. <IMAGE>
Patent DE-69604009-T2 (DE)
Inventor: ALEMAN CLAUDE
IPC: A61K47/18
Filed: 1996-05-09
Granted: 2000-04-06
Abstract: Pharmaceutically acceptable, physically stable, liq. compsn. comprises urate oxidase and 0.1-10 mg/ml Poloxamer 188 (polyoxyethylene / polyoxypropylene copolymer) in a buffered aq. medium. Also claimed is a freeze-dried compsn. contg. Poloxamer 188 and urate oxidase in a wt. ratio of 0.01-50:1 respectively.
Patent DE-69610924-T2 (DE)
Inventor: BRANDS M
IPC: C07D495/08
Filed: 1996-07-31
Granted: 2001-05-17
Abstract: A process of synthesizing a compound of formula (I) is described. A compound of formula (II) is reacted with diphenylphosphinic chloride to activate the carboxylic acid group, and then reacted with methanesulfonyl chloride to produce a compound of formula (IV). Compound (IV) is then reacted with Na2S in water to produce a compound of formula (I).
Patent DE-69612481-T2 (DE)
Inventor: WONG S-L
IPC: A61K9/22
Filed: 1996-02-09
Granted: 2001-07-26
Abstract: The present invention is directed to an active agent dosage form that is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has an insoluble material circumscribing a portion of the surface of the matrix. The invention is also directed to a method of making the active agent dosage form.
Patent DE-69613861-T2 (DE)
Inventor: KAHN MICHAEL
IPC: C07D498/04
Filed: 1996-10-24
Granted: 2001-11-15
Abstract: Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetics have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetics of this invention are also disclosed, as well as methods for screening the same to identify biologically active members.
Patent DE-69616805-T2 (DE)
Inventor: DAVID MICHEL
IPC: A61C7/08
Filed: 1996-07-25
Granted: 2002-06-27
Abstract: Intrabuccal device includes two shells (2, 3) made of thermoformed plastic material, the first of which respectively covers the superior arch, and the second of which covers the inferior arch of the oral cavity. This device is provided with (rings and arms) (4a, 4b, 13a, 13b) that act on the said shells (2, 3) and can generate a mandibular propulsion force oriented in the direction of the mandibular propulsion and in the posteroanterior sense, so as to keep a shift of the mandible to the front of the maxilla, while allowing lateral movements.
Patent DE-69623939-T2 (DE)
Inventor: FLETCHER JOHN
IPC: C09K3/00
Filed: 1996-03-06
Granted: 2003-05-28
Abstract: A description is given of biphenyl-substituted triazine compounds of the formula <CHEM> <??>The biphenyl-substituted triazine compounds, which are notable for high thermal stability, are used as stabilizers for organic polymers to counter damage thereto caused by light, oxygen and heat, as light stabilizers for textile fibre materials, and as sunscreens for the human skin.
Patent DE-69624500-T2 (DE)
Inventor: BOSIES ELMAR
IPC: C07D403/04
Filed: 1996-12-20
Granted: 2003-07-17
Abstract: PCT No. PCT/EP96/05766 Sec. 371 Date Aug. 26, 1998 Sec. 102(e) Date Aug. 26, 1998 PCT Filed Dec. 20, 1996 PCT Pub. No. WO97/23465 PCT Pub. Date Jul. 3, 1997Compounds of formula I, useful as matrix metalloprotease inhibitors, wherein X, Y and Z are each oxygen; R1 is selected from the group consisting of (a) n-octyl, (b) n-decyl, (c) biphenyl and (d) (4-phenoxy)phenyl, wherein the terminal monocycle for moieties (c)-(d) is unsubstituted or substituted by a substituent selected from the group consisting of -NH2, -NO2, -SO2NH2, -SO2CH3, acetyl, hydroxy, methoxy, ethoxy, cyano and halogen; R2 and R3 are each hydrogen; and R4 and R5, together with the nitrogen atom to which they are bound, form a piperazinyl or piperidyl ring, wherein the piperazinyl ring is substituted in the 4-position with a substituent selected from the group consisting of (a) a 6-membered aromatic monocycle having 0, 1 or 2 nitrogen atoms and the remainder of the atoms in the monocycle being carbon and (b) hydroxy-C1-C6 alkyl, wherein the monocycle is unsubstituted or substituted by a substituent selected from the group consisting of halogen, -NH2, -NO2, -SO2NH2, -SO2CH3, acetyl and cyano.
Patent DE-69627222-T2 (DE)
Inventor: FALCONER MALCOLM I
IPC: A61F5/44
Filed: 1996-01-05
Granted: 2003-12-11
Abstract: This leg bag and holder are comfortable to wear, unobtrusive, in which changing of the bag is readily accomplished, and which includes means for ensuring that the bag can be securely held in place on the leg. A combination holder and a leg bag is shown. The holder 10 includes a first sheet 20 of material which can conform to the curvature of the leg, a second sheet 22 of material attached to the first sheet for movement relative to the first sheet generally about an axis, a leg bag 40 having an entry hole 46 at its upper end, and an attachment device 18 connected to the first sheet and capable of passing through one or more holes in the leg bag 40. The attachment device has a movable attachment portion 18B shiftable between a first position which permits the leg bag 40 to be fitted and a second position in which the leg bag is caused to be held in a closed position. It is held closed by the movable attachment portion. The holder 10 must be hinged open to access the clamp 18, so that the leg bag 40 can be fitted as described. <IMAGE>
Patent DE-69630298-T2 (DE)
Inventor: KAZACOS MICHAEL
IPC: H01M8/18
Filed: 1996-05-03
Granted: 2004-09-02
Abstract: Disclosed is a method for preparing a high energy density (HED) electrolyte solution for use in an all-vanadium redox cell, a high energy density electrolyte solution, in particular an all-vanadium high energy density electrolyte solution, a redox cell, in particular an all-vanadium redox cell, comprising the high energy density electrolyte solution, a redox battery, in particular an all-vanadium redox battery, comprising the HED electrolyte solution, a process for recharging a discharged or partially discharged redox battery, in particular an all-vanadium redox battery, comprising the HED electrolyte solution, a process for the production of electricity from a charged redox battery, and in particular a charged all-vanadium redox battery, comprising the HED electrolyte, a redox battery/fuel cell and a process for the production of electricity from a redox battery/fuel cell. A method for stabilising an electrolyte solution for use in a redox cell, in particular for stabilising an electrolyte solution for use in an all-vanadium redox cell, a stabilised electrolyte solution, in particular an all-vanadium stabilised electrolyte solution, a redox cell, in particular an all-vanadium redox cell, comprising the stabilised electrolyte solution, a redox battery, in particular an all-vanadium redox battery, comprising the stabilised electrolyte solution, a process for recharging a discharged or partially discharged redox battery, in particular an all-vanadium redox battery, comprising the stabilised electrolyte solution, and a process for the production of electricity from a charged redox battery, and in particular a charged all-vanadium redox battery, comprising the stabilised electrolyte solution are disclosed. Also disclosed are a redox battery/fuel cell and a process for the production of electricity from a redox battery/fuel cell.
Patent DE-69632796-T2 (DE)
Inventor: RADLEY-SMITH PHILIP JOHN
IPC: G04G9/08
Filed: 1996-01-15
Granted: 2005-07-14
Abstract: A bracelet includes at least one electronic display unit. Each display unit has a display having a plurality of display elements arranged in a sequence lying along the length of the bracelet and/or arranged in a sequence lying substantially around the perimeter of the display. The bracelet has a control circuit to control the display elements so that the characters displayed by the display elements appear to move along the sequence of display elements with time. In the alternative, the characters appear to move along a discrete face which is provided -along the bracelet.
Patent DE-69701859-T2 (DE)
Inventor: CHOPIN THIERRY
IPC: C09D7/62
Filed: 1997-02-12
Granted: 2000-11-09
Abstract: Anatase titanium dioxide particles no larger than 100 nm and coated with a layer of a metal oxide, hydroxide or oxohydroxide, said particles having a BET specific surface area of at least 70 m<2>/g and a density of around 2.2. A method for preparing said particles, and the use thereof as an anti-UV agent, in particular for preparing formulations for cosmetics, varnishes, paints and plastics, are also disclosed.
Patent DE-69712770-T2 (DE)
Inventor: KUKAL OLGA
IPC: G01N33/02
Filed: 1997-10-10
Granted: 2002-09-05
Abstract: The present invention relates to the optimum bio-storage temperature of biological materials. The temperature is between the melting point depression of the biological material and zero degrees C. The melting point depression temperature is determined by thermography, differential scanning calorimetry and cryomicroscopy.
Patent DE-69727497-T2 (DE)
Inventor: UNTERNAHRER ROLAND
IPC: F26B21/02
Filed: 1997-11-06
Granted: 2004-10-07
Abstract: The high-temperature treatment apparatus consists of a treatment chamber and at least one combustion chamber (30) with one or more burners (31) operating inn a reduced atmosphere, and fans (26) to circulate the gases between the combustion and treatment chambers. <??>The apparatus has at least gas intake channel (22) from the treatment chamber, connected to the suction side of each fan, and a return channel (23) feeding the gases back to the treatment chamber. The material treated in the apparatus is pre-heated and dried at a temperature close to that at which water vaporises, is heated in a reduced atmosphere and then cooled by injecting water vapour.
Patent DE-69731738-T2 (DE)
Inventor: HENTTONEN VESA
IPC: B01D29/075
Filed: 1997-02-26
Granted: 2005-11-10
Abstract: PCT No. PCT/FI97/00129 Sec. 371 Date Jan. 4, 1999 Sec. 102(e) Date Jan. 4, 1999 PCT Filed Feb. 26, 1997 PCT Pub. No. WO97/32652 PCT Pub. Date Sep. 12, 1997The invention concerns a method and a device for separation of separable constituents from a liquid medium. The separation device comprises only one cell or a stack of a plurality of adjacent cell, whereby each cell consists of a plate unit containing a filter, an inlet for supplying the liquid medium into a chamber, and outlet for discharging the reject and an outlet for discharging the permeate. The liquid medium is subjected to a strong turbulence created by a convenient designed rotor, possible combined with sound waves, whereby the deposition of separable constituents on the filter is prevented or essentially reduced. According to the invention a rotor is used in which the essentially plane surface of the rotor wings directed toward the filter comprises one or more areas deviating from the plane of said surface; or the surface of the rotor wings directed towards the filter is curved in such a way that the distance between the surface of the wing and the filer is small at the inner portion of the rotor and that said distance gradually increases towards the periphery of the rotor, or the section of the rotor wings in the plane parallel with the filter forms an almost S-shaped surface, whereby the S-shape is continuous.
Patent DE-69734317-T2 (DE)
Inventor: FELDMANN MARC
IPC: A61K39/395
Filed: 1997-08-01
Granted: 2006-07-20
Abstract: Use of a tumour necrosis factor (TNF) antagonist for the preparation of a medicament for treatment of a TNF-mediated disease, wherein the TNF antagonist is to be administered as adjunctive therapy to methotrexate.
Patent DE-69806723-T2 (DE)
Inventor: MAURIZZI MASSIMO
IPC: G06K7/10
Filed: 1998-04-02
Granted: 2003-06-12
Abstract: Reading method for an optical code (10) by means of a reader which comprises photoemitters (7), photoreceivers (12) and a processor circuit (52), in which the following steps are carried out: emitting a radiation (F) towards the exterior of the reader (1); detecting (110) the presence of at least one operating condition of the reader (1); activating (100) a first operating mode in the absence of the operating condition of the reader (1); and activating (110) a second operating mode (120) on detection of the operating condition. <IMAGE>
Patent DE-69811197-T2 (DE)
Inventor: METTAVANT PIERRE
IPC: F16C13/04
Filed: 1998-04-14
Granted: 2003-10-09
Abstract: A support device for a rotary drum having at least one roller capable of cooperating with the drum. At least two bearings permit the rotation of the roller about its axis of rotation. The support device has a chassis into which the bearings are secured. The chassis is mounted for pivoting about a pivotal axis substantially perpendicular to the plane passing through the axis of rotation of the roller and perpendicular to a block onto which the support device is placed. The device also includes a connector which is flexible in a given direction and rigid in the directions orthogonal to the direction of flexibility. The connector maintains the bearings on the block while permitting free pivotal movement of the chassis in such a way to permit alignment of the roller on the drum in the event of pivoting.
Patent DE-69816035-T2 (DE)
Inventor: GIACHINO GIUSEPPE
IPC: A21C9/04
Filed: 1998-05-15
Granted: 2004-03-04
Abstract: A naturally leavening dough (1) is prepared and enriched with such fatty matter (3) as margarine. The dough strip is then subjected to a series of successive processing operations of puffing (4) that create a variable number of superpositions of alternate layers of dough and fatty matter. The laminated dough obtained in this manner is then subjected to continuous leavening in a leavening chamber (5), baked in an oven (7) and eventually stuffed, for example with a fatty cheese-and-tomato-base stuffing cream. The upper layer of the product is garnished - for example - with small strips of peppers and slices of green olives, the product being portioned (divided into portions) only in a subsequent processing phase. <IMAGE>