baber/WOPTO huggingface dataset:
Patent CA-2586547-A1 (CA)
Inventor: BEASLEY MARTIN W
IPC: A61K9/14
Filed: 2005-11-07
Abstract: The present invention relates to novel ramipril crystalline particles with improved stability and bioavailability. More particularly, the present invention is directed to individually coated, single ramipril crystalline particles for pharmaceutical and biopharmaceutical applications in oral therapies that are stabilized against decomposition into degradation products, namely, ramipril-DKP and ramipril-diacid, during formulation and storage conditions. The present invention also relates to stabilized ramipril pharmaceutical compositions, novel anhydrous pharmaceutical grade ramipril powders, methods for improving ramipril bioavailability, and methods of manufacture and stabilization of ramipril formulations. The novel, anhydrous pharmaceutical grade ramipril powders and ramipril compositions and dosage forms formed therewith are useful in the treatment of cardiovascular disorders and have the advantage that they provide greater stability against decomposition into ramipril-DKPs and ramipril-diacids under formulation and storage conditions. In addition, they maintain consistent label ramipril potency over extended shelf-life and provide reduced in vivo variability in the bioavailability of ramipril among subjects when administered orally.
Patent CA-2588439-A1 (CA)
Title: Parking meter
Inventor: MITSCHELE FREDERICK L
IPC: G07C1/30
Filed: 2007-05-14
Abstract: A parking system using parking meters which accept payment by credit card or smart cards. The user can start the parking payment period by swiping a credit card in the reader. A fixed pre-payment is charged to the card. The payment period is terminated when the same card is swiped a second time. The pre-paid charge is cancelled and the card is charged only for the actual elapsed time.
Patent CA-2589051-A1 (CA)
Title: Trycyclic heterocycles, their manufacture and use as pharmaceutical agents
Inventor: GOLLER BERNHARD
IPC: C07D487/04
Filed: 2005-12-16
Abstract: Objects of the present invention are the compounds of formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
Patent CA-2595054-A1 (CA)
Title: Adjustable headrest assembly
Inventor: VIGER DENIS
IPC: A47C7/38
Filed: 2007-06-21
Abstract: A headrest assembly for a chair or sofa includes a fixed rear section, and a front section adapted to slide upwardly and forwardly to an inclined orientation with respect to the rear section. Movement of the front section is controlled by a linear actuator, which is connected via a switch to a source of power such as a battery.
Patent CA-2596186-A1 (CA)
Title: Use of active ingredients containing hydroxystilbene for preventing and/or treating osteoporosis
Inventor: RETTENBERGER REINHARD
IPC: A61K36/708
Filed: 2006-02-03
Abstract: The invention relates to the use of a combination of active ingredients containing hydroxystilbene, selected from resveratrol and piceatannol precursors and functional derivatives thereof, in addition to the use of the stereoisomeric forms of said ingredients, in the form of salts or phenol respectively, for producing an agent for the prevention and/or treatment of osteoporosis.
Patent CA-2596559-A1 (CA)
Inventor: TAYLOR MICHAEL
IPC: B24B15/02
Filed: 2006-02-09
Abstract: A clutch mechanism for a slurry valve, wherein the slurry valve has a valve seat for seating a valve closure member carried on a valve stem, a drive member threadably engaged with the valve stem, the drive member being rotatable relative to the valve stem to axially move the valve stem and closure member relative to the valve seat to open and close the slurry valve, and a driving means for rotating the drive member, the clutch mechanism comprising: a clutch body having an internally threaded bore for threadably receiving the valve stem; and clamping means actuable with the clutch body for clamping the clutch body to the driving means so as to lock the valve stem and drive member together and allow them to rotate in unison to grind scale from the valve seat and valve closure member when they are positioned against each other.
Patent CA-2600323-A1 (CA)
Title: Directly actuated valve with a strain-type actuator and a method of operating same
IPC: F16K31/02
Filed: 2007-09-20
Abstract: Disclosed is a method of operating a directly actuated valve that comprises a strain-type actuator to actuate a valve member to travel between a closed position and a n open position, the method comprising maintaining a compressive stress on the actuator that is greater than a predetermined minimum pressure by applying a pre-load compressive stress and limiting to less than predetermined limits at least one of: (a) acceleration and deceleration of the valve member when moving between open positions and the closed position; and (b) velocity of said valve member immediately before contactin g the valve seat. One of the preferred techniques for limiting the velocity of the valve member while also reducing the amount of fluid that flows through the valve during the closing time, comprises changing the closing rate of the valve member so that the valve member travels most of the closing distance quickly during the beginning of a closi ng movement, and then slowing down the closing rate of the valve member in a second porti on of the closing movement, so that the velocity of the valve member is less than a predetermined limit immediately before contacting the valve seat.
Patent CA-2601029-A1 (CA)
Title: Photoproteins with enhanced bioluminescence and their use as intracellular calcium indicators
Inventor: MASTROIANNI NADIA
IPC: C07K14/435
Filed: 2006-03-09
Abstract: The present invention relates to photoproteins with enhanced bioluminescence obtained by mutagenesis of clytin, to their use as intracellular calcium indicators and in cell-based assays.
Patent CA-2601982-A1 (CA)
Inventor: HANSEN JENS A
IPC: C10G45/54
Filed: 2005-12-13
Abstract: A process for hydrocracking a hydrocarbon feedstock comprising components boiling above 343~C into a middle distillate fraction in the presence of hydrogen under hydrocracking conditions, comprising contacting the hydrocarbon feedstock in a first hydrocracking zone in the presence of one or more hydrocracking catalysts and thereafter in a second hydrocracking zone in the presence of one or more hydrocracking catalysts, and recovering a middle distillate product, wherein the entire effluent from the first hydrocracking zone is passed into the second hydrocracking zone, and at least one hycrocracking catalyst in the first hydrocracking zone comprises one or more hydrogenation components on a support comprising at least one large pore zeolite having a pore diameter in the range of 0.7 - 1.5 nm and at least one inorganic oxide, and at least one hydrocracking catalyst in the second hydrocracking zone comprises one or more hydrogenation component on a support comprising a beta zeolite and at least one inorganic oxide.
Patent CA-2602166-A1 (CA)
Inventor: FOX BART W
IPC: B32B5/18
Filed: 2006-03-16
Abstract: A process for providing a cushioned region (14) on a substrate (12) is disclosed. The substrate (12) is at least partially covered by a sheet (18) of preferably textured material. A skin (22) is coupled to the substrate (12) and a compressible material (24) (such as foam) is injected between the sheet (22) and skin (24). The sheet (18) is intended to promote adhesion to the compressible material (24) (e.g., mechanical and/or chemical joining or bonding). If portions of the coversheet (18) are exposed on a visible surface, the coversheet may also be configured to provide a decorative or ornamental appearances.
Patent CA-2602203-A1 (CA)
Title: Apparatus and method for constructing a semantic layer based on xbrl data
Inventor: MUELLER-KLINGSPOR DIANE CAROL
IPC: G06F9/44
Filed: 2006-04-04
Abstract: A computer readable medium includes executable instructions to construct a semantic layer schema based on an XBRL data source and maintain the integrity of the XBRL metadata. The XBRL data can then be loaded into the semantic layer schema, and refreshed, such that the XBRL data is assessed and the semantic layer schema is updated as required.
Patent CA-2602368-A1 (CA)
Inventor: RIVIERE PIERRE J-M
IPC: A61K31/17
Filed: 2006-04-26
Abstract: The present invention relates to use of novel compounds for the manufacture of a medicament for treatment of inflammatory bowel disease (IBD) as well as to a method for treatment of IBD, wherein said compounds are administered. The compounds are represented by the general formula (I) , as further defined in the specification.
Patent CA-2606278-A1 (CA)
Title: Heat exchanger system having manifolds structurally integrated with a duct
Inventor: ZEARBAUGH SCOTT RICHARD
IPC: F28F9/02
Filed: 2007-10-11
Abstract: A heat exchanger system (20) includes a duct (22) having a duct wall (24) with a duct wall outer surface (42) and a duct wall inner surface (44); and a heat exchanger partial shell (46) joined to the duct wall inner surface (44). The heat exchanger partial shell (46) and a shell portion (48) of the duct wall inner surface (44) constitute a heat exchanger (32). A heat exchanger inlet manifold (38) is defined by a nonplanar inlet sheet (56) of material joined to the duct wall outer surface (42). A heat exchanger outlet manifold (40) is defined by a nonplanar outlet sheet (66) of material joined to the duct wall outer surface (42). A  heat exchanger inlet opening (64) extends through the duct wall (24) between the inlet manifold (38) and the heat exchanger (32), and a heat exchanger outlet opening (74) extends through the duct wall (24) between the outlet manifold (40) and the heat exchanger (32).
Patent CA-2606419-A1 (CA)
Inventor: MCDANIEL JOSEPH B
IPC: B29C48/32
Filed: 2006-04-19
Abstract: A heat-shrinkable polylactic acid (PLA) film and a method of its manufacture are provided. In an exemplary embodiment, the PLA films exhibit heat-induced growth in the cross direction with concomitant shrinkage in the machine direction. The films may comprise any grade of PLA polymer, optionally including additives, such as antiblock, slip, viscosity enhancers and combinations thereof. A method of manufacture is disclosed which includes a post-extrusion temperature conditioning step.
Patent CA-2607321-A1 (CA)
Inventor: BECH NIELS
IPC: C10B47/22
Filed: 2006-05-03
Abstract: A method for collecting biomass, such as straw, and for producing a pyrolysis liquid, such as oil or tar, from the biomass, comprises the step of collecting the biomass from a growth site, e.g. a field, by means of a mobile unit. The biomass is continuously fed into a pyrolysis apparatus (200) accommodated by the mobile unit, as the mobile unit is moved across the growth site. While the biomass is processed in the pyrolysis apparatus, further biomass is simultaneously being collected. The pyrolysis apparatus may be a flash pyrolysis or fast pyrolysis apparatus relying on centrifugal forces for forcing biomass towards a reactive surface in a pyrolysis reactor. The mobile unit may be self-propelled.
Patent CA-2613027-A1 (CA)
Inventor: PENTAFRAGAS DIMITRIOS
IPC: A61M15/00
Filed: 2002-09-25
Abstract: An inhalation device for the uptake of medicaments that are in the form of dry powder contained in the blisters of specially designed single dose blister strips. The device is comprised of a mouthpiece (A), a strip support surface area (B), and one or more storage areas (C). Furthermore, the single dose blister strip is described. It is comprised of two sheets (17, 20) that are fixed in such a manner so that when they get separated the powder becomes available for inhalation.
Patent CA-2614247-A1 (CA)
Title: Vehicle and lane mark recognition apparatus
Inventor: KOBAYASHI SACHIO
IPC: G06V10/28
Filed: 2006-06-23
Abstract: A lane mark recognition apparatus has an image acquisition means (30) for acquiring a color image (IM_0) of a road via a color video camera (10), a specific-color-extracted image creation means (31) for creating both a brightness-extracted image (IM_1) obtained by extracting white-color data from the color image (IM_0) and a yellow-color-extracted image (IM_2) obtained by extracting yellow-color data from the color image (IM_0), and a lane mark detection means (50a) detecting a while line and a yellow line from a composite image (IM_C) formed by the brightness-extracted image (IM_1) and the yellow-color-extracted image (IM_2) and outputting positional data (Pd1) of the white line and positional data (Pd2) of the yellow line.
Patent CA-2615559-A1 (CA)
Inventor: DAYA SHAHIR AMIRALI
IPC: H04L9/32
Filed: 2007-12-20
Abstract: Searching content of a portal comprising a plurality of portal content elements, at least one of which is a secure portal content clement. Each secure portal content element is associated with a unique identifier. Search parameters and credentials are received from a user, and a preliminary result set satisfying the search parameters is generated. For each secure portal content element in the preliminary result set, the credentials and the unique identifier are used to determine whether the user is permitted to access that secure portal content element. The preliminary result set is used to generate a final result set. A result identification is presented to the user, identifying the secure portal content elements that are included in the final result set and which the user is permitted to access, with such secure portal content elements being distinguished from any secure portal content elements to which the user is denied access.
Patent CA-2616043-A1 (CA)
Title: Apparatus for dispensing granular material and method thereof
Inventor: PENDLETON STEVENS P
IPC: B67D7/08
Filed: 2006-06-20
Abstract: An apparatus for dispensing granular material, such as flux powder to a mold for continuous casting of metal, has an intermediate chamber, a dispensing hopper, and a conduit communicating the interior of the chamber to the interior of the hopper. The conduit has a rotatable auger running through its length, the auger reaching from within the interior space of the chamber into the interior hopper for transferring material from the chamber into the hopper. A dispensing line communicates with a bottom of the hopper at a transfer point for receiving material from the hopper and dispensing the material toward a dispensing end of the line. Pressurized air is supplied to the line, upstream of the transfer point, and a sealing cap is provided for actuating into sealing engagement with a hopper end of the conduit. A second inlet for pressurized air is provided such that air may be supplied directly into the hopper above the fill line. An automatic control processor links the various components, and provides for sequential operation. The material is conveyed batch-wise from the chamber into the hopper, and is not dispensed into the line until the chamber access has been sealed, thus preventing backflow into the chamber.
Patent CA-2618172-A1 (CA)
Title: Method and apparatus for enhancing formation resistivity images obtained with downhole galvanic tools
Inventor: GOLD RANDY
IPC: E21B47/01
Filed: 2006-08-04
Abstract: The average current at a plurality of measure electrodes of a resistivity imaging tool is determined and subtracted from the individual measure currents to give a resistivity image with improved dynamic range.
Patent CA-2618609-A1 (CA)
Title: Chemical injection for vehicle wash system and method
Inventor: ROWLANDS CHRIS
IPC: B08B3/08
Filed: 2008-01-15
Abstract: An apparatus includes an application pump that pumps water through a water application line. Fast-acting valves control a flow of different chemical concentrates into the water application line, and a controller is connected to each of the valves and programmed with a chemical injection pulse solenoid algorithm for optimal control of the chemical concentrate. The apparatus provides direct chemical injection into vehicle wash systems through the use of the fast-acting solenoid valves which rapidly turned on and off, creating an accurate and variable means of metering highly concentrated chemicals. Algorithms are used to control operation of the fast-acting solenoids, "pulsing" them in accordance to chemical type and application. The particular algorithm used preferably balances end performance and consistency with mechanical considerations such as actuation lag time, valve longevity, and wash equipment variables.
Patent CA-2619014-A1 (CA)
Inventor: BOYD THOMAS J
IPC: A61Q11/00
Filed: 2006-08-16
Abstract: The invention is directed to an oral composition that contains an amphoteric surfactant and an homo- or copolymer comprising an ethylenic monomer and related methods. The ethylenic monomer includes a phosphonate group. The monomer may be represented by the structure of Formula (I), wherein one of A  and A' is a hydrogen atom and the other is selected from a hydrogen atom or a group -(X)nRm; wherein n is i\selected from 0 or 1; provided that when n is 0, m is 1, and when n is 1, m is an integer of 1 to 3; X is selected from an oxygen atom, a sulfur atom, a nitrogen atom, a phosphorous atom, and silicon atom; R is independently a hyuderogen atom or an arganic radical; L is selected from a bond and a linking group; M and M' are independently selected from a hydrogen atom, an alkali metal, and an ammonium ion, or together form an alkaline earth metal or other divalent element; and p is 1 or 2, provided that when L is a bond, p is 1.
Patent CA-2626006-A1 (CA)
Inventor: BLIGH ROGER P
IPC: E01F15/04
Filed: 2006-09-08
Abstract: In accordance with a particular embodiment of the present invention, a guardrail system includes at least one cable operable to contain and redirect an errant vehicle. The guardrail system also includes a plurality of guardrail support posts spaced apart in relation to one another. Each support post includes a lower portion, a mid portion, and an upper portion. The lower portion is for installing below grade adjacent the roadway. The mid portion lies substantially adjacent the grade and includes a weakened section operable to weaken the support post about a longitudinal axis. The upper portion is releasably coupled to the at least one cable such that the upper portion is uncoupled from the at least one cable when the support post is displaced.
Patent CA-2626672-A1 (CA)
Inventor: BARTHOLOMEUSZ ANGELINE INGRID
IPC: C12N15/51
Filed: 2006-10-20
Abstract: The present invention relates generally to viral variants exhibiting reduced sensitivity to agents such as nucleoside or nucleotide analogs or other DNA  polymerase antagonists and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B  virus (HBV) variants exhibiting complete or partial resistance to nucleoside or nucleotide analogs or other DNA polymerase antagonists and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies. The present invention further contemplates assays for detecting such viral variants, which assays are useful in monitoring anti-viral therapeutic regimens and in developing new or modified vaccines directed against viral agents and in particular HBV variants. The present invention also contemplates the use of the viral variants to screen for and/or develop or design agents capable of inhibiting infection, replication and/or release of the virus.
Patent CA-2631697-A1 (CA)
Title: Process for the preparation of aromatic derivatives of 1-adamantane
Inventor: COMELY ALEXANDER CHRISTIAN
IPC: C07C51/15
Filed: 2006-12-01
Abstract: Process for the obtaining of 1 -adamantane (tricycle[3.3.1.1 (3,7)]decane) derivatives, or of a pharmaceutically acceptable salt thereof, based on a carboxylation reaction, via metallation, of a precursor compound with an adequate leaving group. It also comprises the preparation of the precursor compound by means of a selective coupling of the corresponding boron, magnesium or zinc derivative with the corresponding disubstitute aromatic derivative. It is especially useful for the obtaining of Adapalene at industrial scale with good yield and high purity.
Patent CA-2635156-A1 (CA)
Title: Swimming goggles
Inventor: CHIANG HERMAN
IPC: A63B33/00
Filed: 2008-06-17
Abstract: Swimming goggles are provided which include an integral left and right frames and nose bridge. The integral left and right frames and nose bridge include an outer frame and an inner frame. The outer frame includes front sections of the left and right frames, and a front section of the nose bridge. The inner frame includes rear sections of the left and right frames, and a rear section of the nose bridge. Lenses are received in the left and right frames of the outer frame and the inner frame. Pads are made of soft material and are assembled on the rear sections of the left and right frames. The outer frame and the inner frame are made of different material or of the same material with different rigidity.
Patent CA-2638016-A1 (CA)
Inventor: CARRIER DAVID O
IPC: F16H1/16
Filed: 2007-01-23
Abstract: A worm-gear assembly including a worm screw ()280 having at least one groove ()280a and a wheel (275) having a plurality of rotatable pins (75a) along its periphery for engaging the worm screw. The pins are able to rotate in a direction other than a direction of wheel rotation. At least one raceway (265) is provided for contacting pins that are not engaged with the worm screw during operation of the assembly.
Patent CA-2638851-A1 (CA)
Inventor: TUR MEHMET
IPC: A61K39/395
Filed: 2007-02-21
Abstract: The present invention relates to human thymic stromal lymphopoietin (hTSLP) antibodies and especially those which neutralize hTSLP activity. It further relates to methods for using anti- hTSLP antibody molecules in diagnosis or treatment of hTSLP related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.
Patent CA-2641037-A1 (CA)
Inventor: DEGROOT MICHAEL
IPC: B65G19/00
Filed: 2007-01-31
Abstract: L'invention concerne un raccord de courroie denté permettant de constituer une courroie sans fin. Ledit raccord comprend deux feuilles conçues pour être raccordées l'une à l'autre par des articulations le long d'une ou de plusieurs dents. Chaque articulation comprend au moins un trou qui s'étend à travers des parties dents de façon que lorsque les trous sont alignés, une broche puisse être introduite dans lesdits trous afin de raccorder les feuilles au niveau des dents. Les feuilles peuvent être assemblées aux extrémités d'une courroie afin d'obtenir la courroie sans fin. L'embout de chaque articulation peut être biseauté ou peut présenter un doigt formant une marche qui est inséré dans une partie découpée sur la feuille opposée de façon à empêcher l'extrémité d'une articulation de faire saillie lorsque la courroie s'enroule autour d'une roue dentée.
Patent CA-2641729-A1 (CA)
Inventor: OGATA WAYNE
IPC: A61B17/22
Filed: 2007-02-12
Abstract: A method and systems for treating chronic total occlusions, particularly those that are difficult to treat, is disclosed. In this approach, recanalizing the CTO is achieved using a combined antegrade and retrograde approach. The proximal end of the occlusion is penetrated using an antegrade wire, using a traditional approach. Using collateral vessels, the distal end of the occlusion is crossed in a retrograde fashion and by appropriately maneuvering each member, a continuous channel is created. Additional elements such as capture devices, dilators and injection catheters are also disclosed.