baber/WOPTO huggingface dataset:
Patent WO-2022016035-A1 (WO)
Title: Β-glucuronidase proteins having pneumococcal capsule degrading activity and methods of use
Inventor: AVCI FIKRI Y
IPC: A61P11/00
Filed: 2021-07-16
Abstract: The present disclosure includes catalytically active truncations of a protein, referred to as a PnSPase protein, that degrade the capsular polysaccharide of serotype 3  Streptococcus pneumoniae . The disclosure includes a genetically modified cell that includes a PnSPase protein of the present disclosure, and compositions that include the protein, the polynucleotide encoding the protein, the genetically modified cell, or a combination thereof. Also provided are methods for using a PnSPase protein of the present disclosure, including methods for contacting a  S. pneumoniae  having a type III capsular polysaccharide with a PnSPase protein, increasing deposition of at least one complement component on the surface of a  S. pneumoniae , treating an infection in a subject, treating a symptom in a subject, decreasing colonization of a subject by  S. pneumoniae , or a combination thereof.
Patent WO-2022026374-A1 (WO)
Title: Jeton cryptographique avec groupes de circulation séparés
Inventor: LONG CAITLIN
IPC: G06Q20/38
Filed: 2021-07-26
Abstract: L'invention concerne un jeton cryptographique personnalisé et un contrat intelligent personnalisés qui sont configurés pour exister dans l'un de deux groupes et sont émis par la même banque ou institution de dépôt qui collecte également des dépôts en monnaie fiduciaire correspondants. Les deux groupes sont un groupe de circulation et un groupe de non-circulation. Le groupe de non-circulation n'est pas associé à un quelconque utilisateur donné, mais plutôt une entité émettrice. Des jetons cryptographiques personnalisés résidant dans le groupe de circulation sont associés à un utilisateur et sont négociés conformément au protocole de contrat intelligent.
Patent WO-2022026570-A1 (WO)
Inventor: KAWAHARA CRAIG
IPC: G06Q20/32
Filed: 2021-07-28
Abstract: Methods and systems for improved exit detection, payment confirmation, and payment authorization verification are provided. In one embodiment, a method is provided that includes transmitting an audio transmission that includes a unique identifier of a facility. The audio transmission may be transmitted to a computing device, which may transmit in response an audio transmission containing a unique identifier and a payment confirmation identifier. The payment confirmation identifier may be compared to a database of payment information and it may be determined that the payment confirmation identifier corresponds to a completed payment. It may further be determined that the user has completed a payment and is permitted to exit the facility.
Patent WO-2022066287-A1 (WO)
Inventor: LIN CHI-MING
IPC: H04N5/225
Filed: 2021-08-02
Abstract: This document describes a security camera with an angled cable attachment for an increased downward viewing angle. The security camera is battery-powered and can be magnetically coupled to a mounting device and electrically connected to another device via a cable. The cable has a cable attachment that, when coupled to the security camera, is angled toward a front of the security camera. This cable angle enables an increased downward tilt angle of the security camera by reducing interference of the cable attachment with the mounting device when the security camera is tilted downward. The security camera also has exposed contacts on a printed circuit board that connect with pins on the cable attachment.
Patent WO-2022036098-A1 (WO)
Title: Pumped heat energy storage system with steam cycle
Inventor: BOLLINGER BENJAMIN R
IPC: F01K13/00
Filed: 2021-08-12
Abstract: The present disclosure provides pumped heat energy storage systems that can be used to store and/or extract electrical energy. A pumped heat energy storage system of the present disclosure can store energy by operating as a heat pump, whereby net work input can be used to transfer heat from the cold side to the hot side. A working fluid of the system is capable of efficient heat exchange with heat storage fluids on a hot side of the system and on a cold side of the system. Such pumped energy storage systems can be beneficially integrated with steam plants to provided heating to the steam cycle.
Patent WO-2022040194-A1 (WO)
Inventor: DELGADO-NANEZ RICARDO
IPC: F24S30/425
Filed: 2021-08-17
Abstract: A solar tracker including at least one pair of piers configured to be secured in the ground and defining a span between the pair, a bearing supported on the pier, and a torque tube supported in the bearing such that the bearing enables rotation of the torque tube, the torque tube including a double wall thickness area, wherein the double wall thickness area limits deflection of the torque tube along the span.
Patent WO-2022047317-A1 (WO)
Title: Csi report triggering for sps pdsch
Inventor: ELSHAFIE AHMED
IPC: H04L1/16
Filed: 2021-08-30
Abstract: To provide hybrid automatic repeat request (HARQ) feedback transmission with channel state information (CSI) report, a UE may receive triggering information associated with transmitting one or more channel state information (CSI) reports associated with one or more downlink (DL) semi-persistent scheduling (SPS) transmissions in one or more physical downlink shared channel (PDSCH) occasions. The UE may receive a first DL SPS transmission of the one or more DL SPS transmissions in a first PDSCH occasion of the one or more PDSCH occasions. The UE may transmit a first CSI report associated with the first DL SPS transmission based on receiving the triggering information.
Patent WO-2023282922-A1 (WO)
Title: Fils pour électrode à manchon hélicoïde multi-applications et systèmes et procédés associés
Inventor: BRANDT WILLIAM
IPC: A61N1/05
Filed: 2021-09-01
Abstract: L'invention concerne une électrode qui comprend un corps de fil allongé et un manchon. Le manchon peut comprendre un corps de manchon hélicoïde biologiquement compatible, élastique, électriquement isolant, configuré pour être disposé autour d'un nerf, et une pluralité de contacts électriquement conducteurs supportés par le corps de manchon hélicoïde qui sont espacés les uns des autres.
Patent WO-2022056000-A1 (WO)
Inventor: GROMADA JESPER
IPC: C12N15/113
Filed: 2021-09-08
Abstract: L'invention concerne des compositions et des méthodes de traitement de la dystrophie musculaire de Duchenne (DMD).
Patent WO-2022056009-A1 (WO)
Title: Apparatus, system, and method of time allocation within a transmit opportunity
Inventor: CARIOU LAURENT
IPC: H04W74/08
Filed: 2021-09-08
Abstract: For example, a trigger frame may be communicated from an Access Point (AP) Station (STA) to a non-AP STA. The trigger frame may be configured to indicate an allocation of an allocated time for the non-AP STA within a Transmit Opportunity (TxOP) of the AP STA, the allocated time configured for transmission of one or more non Trigger Based (non-TB) Physical layer (PHY) Protocol Data Units (PPDUs) from the non-AP STA.
Patent WO-2022066477-A1 (WO)
Title: Shear ram with vertical shear control
Inventor: YENDELL ELLIOT
IPC: E21B33/06
Filed: 2021-09-15
Abstract: A blade (400) includes a blade body (402) extending a blade length (404) and having a blade depth (406). The blade (400) also includes a flat (408), arranged at a forward face, extending a flat length (410), less than the blade length (404). The blade (400) further includes at least one slant (414, 416), arranged at the forward face, the at least one slant (414, 416) being coupled to the flat (408) and positioned at a slant angle (422), wherein the at least one slant (414, 416) includes a cutting edge (418, 420).
Patent WO-2022061232-A1 (WO)
Title: Implantable hydrogel materials and methods for treatment of growth plate injury
Inventor: TABOAS JUAN M
IPC: A61L27/56
Filed: 2021-09-20
Abstract: Disclosed herein implantable material and methods for treatment of growth plate injuries and other purposes. These materials can be particularly useful for treating children whose growth plates are active, and can help encourage proper healing and inhibit unwanted bone formations. Exemplary compositions can comprise poly (ethylene glycol) ("PEG"), gelatin ("GEL"), and heparin ("HEP"). The PEG, GEL, and HEP components can be present in various forms of these materials, such as methacrylated forms, etc. The implanted materials can be anti-osteogenic and/or ant-mineralization, and can help prevent unwanted bone growth in the implanted area, such as boney tethers, which can inhibit desirable growth plate healing and overall bone growth.
Patent WO-2022081973-A1 (WO)
Inventor: LAZERWITH SCOTT E
IPC: A61K45/06
Filed: 2021-10-15
Abstract: Compounds and methods of using said compounds, alone or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
Patent WO-2023069059-A1 (WO)
Title: Chip-based cartridge for biological detection and uses thereof
Inventor: WANG ERICK
IPC: G01N27/327
Filed: 2021-10-18
Abstract: The present invention provides a chip-based cartridge for biological detection and a detection method thereof, comprising a body formed by a flow guiding layer stacking with a substrate. The substrate has a reaction area positioned on part of the electrodes, and the reaction area is coated with a receptor for binding the detection target; The flow guiding layer has an opening aligned with the reaction area, the receptor is exposed at the opening corresponding to the body, and a microfluidic channel is formed between the flow guiding layer and the substrate; The sample is directly dropped from the opening to the reaction area to react with the receptor. After the reaction time, wash buffer is added to the sample in the reaction area. Then, the detection buffer is dropped into the reaction area so as to complete the sample detection without external driving force while improving the detection efficiency.
Patent WO-2022087237-A1 (WO)
Inventor: DIAZ JUAN
IPC: G06F16/2458
Filed: 2021-10-21
Abstract: A method (300) for determining code similarity includes receiving a file (112), identifying executable portions (212) of the file, dividing the executable portions of the file into code blocks (214), generating a hash (222) to represent each code block, and storing the file in a database as a sequence of the hashes. The method further includes receiving a query (140) to identify whether a first file stored in the database is similar to any other file stored in the database. The method additionally includes determining whether any hash associated with the first file matches any of the hashes associated with each other file stored in the database. When one of the hashes associated with the first file matches one of the hashes associated with a second file stored in the database, the method also includes responding to the query that the second file is similar to the first file.
Patent WO-2022109289-A1 (WO)
Title: Compositions and methods for incorporation of dna into the genome of an organism
Inventor: BEILINSON VADIM
IPC: C07K14/195
Filed: 2021-11-19
Abstract: Methods and compositions are provided which allow for genetic modification of host cells, including plants and plant cells. The various methods and composition employ a recombinant DNA construct comprising SEQ ID NO: 1 and/or 2 or active variants and fragments thereof. Such polynucleotides find use in facilitating integration of polynucleotides of interest into the DNA of a host cell, including a plant or plant cell. Vectors, host cells, bacteria and plants comprising the recombinant DNA construct or fragments thereof are provided. Further provided are methods of introducing into a host cell or a plant cell a polynucleotide of interest. The method comprises contacting the host cell with a bacterium competent for the transformation of the host cell and comprises a transformation vector comprising a recombinant DNA construct.
Patent WO-2022140301-A1 (WO)
Title: Airway support device
Inventor: LAZZARO RICHARD
IPC: A61F2/04
Filed: 2021-12-20
Abstract: An airway support device of the present disclosure can be attached to tracheal and/or bronchial cartilage on opposing sides of a tracheal and/or bronchial wall to pull the tracheal and/or bronchial cartilages toward each other to reconstruct and/or reshape to a normal anatomy across the membranous tracheal and/or bronchial wall and thus relieving tension across the tracheal and/or bronchial wall. The airway support device can include at least two longitudinal strips that extend longitudinally along and are attached (e.g., sutured) to the trachea and/or bronchus on opposite sides of the tracheal and/or bronchial wall. Lateral strips extending between the longitudinal strips can stretch across the tracheal and/or bronchial wall while under tension. The tracheal and/or bronchial wall can be attached (e.g., sutured) to the lateral strips to open the airway of the trachea and/or bronchus.
Patent WO-2022133466-A1 (WO)
Inventor: WANG XIAOSONG
IPC: G01N31/00
Filed: 2021-12-16
Abstract: L'invention concerne une méthode de modélisation d'une réponse thérapeutique d'une cellule cancéreuse ou d'une tumeur, consistant à : calculer un poids pour chacune d'une pluralité de caractéristiques multi-omiques redondantes à dimensions élevées qui prédisent une sensibilité vis-à-vis d'agents ou d'autres caractéristiques cliniques sur la base de méthodes d'apprentissage statistique ou machine ; et calculer un score de signature génomique intégrale pour la cellule cancéreuse ou la tumeur sur la base des poids, tout en résolvant de manière algorithmique la redondance de caractéristiques sur la base de jeux de données génomiques non marqués pour de grandes cohortes de tumeurs humaines. L'invention concerne également un modèle iGenSig pour un agent qui calcule la probabilité de réponse ou de résistance d'un patient ayant un cancer ou une tumeur à un traitement avec l'agent. L'invention concerne également une méthode de sélection d'un patient ayant un cancer ou une tumeur pour un traitement avec un agent. L'invention concerne en outre une méthode de traitement d'un patient atteint d'un cancer ou d'une tumeur.
Patent WO-2022165422-A1 (WO)
Title: 2d polymer based targets for serial x-ray crystallography
Inventor: KUHL TONYA L
IPC: G01N23/20025
Filed: 2022-02-01
Abstract: Systems and methods for producing and using polymer based fixed targets for hydrated, room temperature, high-throughput serial protein crystallography with minimal background and minimal sample consumption are provided. The fixed targets can also be used with non-protein samples such as nanoparticle inorganic crystals. The targets maintain full crystal hydration that allows for on-chip crystallization as well as maintaining long term stability of the sample within the chip. The target chips are optimized to minimize background by controlling the sample thickness in the beam to match crystal size, enabling fast raster scanning at lower fidelity and high hit rates that facilitate dynamic measurements. The targets provide an inexpensive, flexible substrate for on-chip, micro-batch or vapor diffusion crystallization facilitated by polymer brushes for sample concentration and surface initiated crystallization thereby eliminating damaging crystal sample transfer.
Patent WO-2022177803-A1 (WO)
Inventor: MALHOTRA RAJIL
IPC: H04W24/02
Filed: 2022-02-10
Abstract: A data communication network (100) serves User Equipment (UE) (101) over an optimal wireless network slice (160) for a user application (112). A Network Exposure Function (NEF) (140) receives a notice message indicating a UE Identifier (ID) for the UE (101) and an application ID for the user application (112) when the UE (101) downloads the user application (112). In response, the NEF (140) transfers a download message indicating the UE ID and the application ID to a network control-plane (130). The network control-plane (130) receives the download message from the NEF (140), and in response, selects a slice ID for the optimal network slice (160) based on the application ID for the user application (112). The network control-plane (130) transfers a slice message indicating the application ID and the slice ID to the UE (101). In response to the slice message, the UE (101) uses the optimal network slice (160) when executing the user application (112).
Patent WO-2022177907-A1 (WO)
Inventor: Lathers Steven
IPC: A61B17/34
Filed: 2022-02-15
Abstract: A trocar assembly includes a trocar including an elongated tubular member extending between a distal end configured to be inserted into a surgical site and a proximal portion including a trocar housing configured for introduction of surgical instmments into the tubular member, wherein the trocar housing includes at least one latch receptacle. The assembly includes a cap, wherein the housing of the cap is attached to the proximal portion of a trocar. The cap includes a housing configured to be removably attached to a proximal portion of a trocar. The housing includes a flow passage therethrough from a distal end of the housing to a proximal opening of the housing. A filter medium is included within the housing spanning the flow passage for filtration of flow through the flow passage.
Patent WO-2022178162-A1 (WO)
Title: Système et procédé d'augmentation de données et de traitement vocal dans des environnements acoustiques dynamiques
Inventor: NAYLOR PATRICK A
IPC: G10L15/16
Filed: 2022-02-17
Abstract: Procédé, produit-programme informatique et système informatique pour définir un modèle représentatif d'une pluralité de variations acoustiques pour un signal vocal, définissant ainsi une pluralité de modifications spectrales variant dans le temps. La pluralité de modifications spectrales variant dans le temps peut être appliquée à un signal de référence en utilisant une opération de filtrage, générant ainsi un signal à spectre augmenté variant dans le temps.
Patent WO-2022182859-A1 (WO)
Title: Broyeur et appareil de remplissage combinés
Inventor: EDWARDS LOUIE
IPC: A24B7/14
Filed: 2022-02-24
Abstract: L'invention concerne un broyeur et un appareil de labourage combinés pour matière végétale utilisés pour déposer de petites particules de matière végétale dans un cône préformé. L'appareil comprend un capuchon d'extrémité rotatif monté sur un corps de broyeur. Une cavité de remplissage dans laquelle est placée la matière végétale en vrac est formée sur le corps de broyeur. Des couteaux qui coupent la matière végétale lorsque le capuchon d'extrémité est placé sur le corps de broyeur et pivoté sont formés dans le capuchon d'extrémité ou dans le corps de broyeur. Une plaque de collecte avec des trous qui permettent à de petites particules de pénétrer dans une cavité de réception de forme conique formée sur un corps de liaison est disposée sous le corps de broyeur. Un capuchon d'extrémité inférieur avec un alésage inférieur dans lequel s'étend le col inférieur du corps de collecte est fixé au corps de collecte. Des bras de pressage situés sur le capuchon d'extrémité inférieur appuient automatiquement contre un cône pré-roulé s'étendant autour du col inférieur. Un piston s'étend dans l'appareil pour emballer la petite matière végétale dans le cône pré-roulé. Un agitateur couplé au piston est positionné dans la cavité de réception et utilisé pour séparer les petites particules de plante.
Patent WO-2022187189-A1 (WO)
Inventor: HAN DONG
IPC: H04W72/12
Filed: 2022-03-01
Abstract: Un support de stockage lisible par ordinateur stocke des instructions pour configurer un UE pour des transmissions avec répétitions de porteuses composantes multiples dans un réseau 5G NR, et pour amener l'UE à effectuer des opérations comprenant un décodage de DCI reçues par l'intermédiaire d'un PDCCH. Les DCI comprennent des informations de bloc de transport (TB) et des informations de planification. Les informations de planification indiquent des transmissions planifiées de répétitions multiples d'un TB de PDSCH à l'aide de porteuses composantes multiples. Une taille de TB associée aux transmissions planifiées est déterminée à l'aide des informations de TB. Les répétitions multiples du TB de PDSCH sont décodées. Les répétitions multiples sont reçues en provenance d'une ou plusieurs stations de base durant les transmissions planifiées. Des données de PDSCH sont déterminées sur la base des répétitions multiples du TB de PDSCH et de la taille de TB.
Patent WO-2022197910-A1 (WO)
Title: Vehicle speaker system
Inventor: SUMMERS GARY
IPC: B60R11/00
Filed: 2022-03-17
Abstract: The present invention encompasses systems and methods for mounting speakers in the front of a vehicle to address multiple issues that exist with audio systems currently on the market. More specifically, the present invention improves and optimizes the phase correct and time correct aspects of existing technologies.
Patent WO-2022212915-A1 (WO)
Inventor: KRANSKI JEFF
IPC: G06N20/20
Filed: 2022-04-01
Abstract: Provided is a process that includes obtaining data indicative of state of a dynamic mechanical system and an environment of the dynamic mechanical system, the data comprising a plurality of channels of data from a plurality of different sensors including a plurality of cameras and other sensors indicative of state of actuators of the dynamic mechanical system; forming a training set from the obtained data by segmenting the data by time and grouping segments from the different channels by time to form units of training data that span different channels among the plurality of channels; training a metric learning model to encode inputs corresponding to the plurality of channels as vectors in an embedding space with self-supervised learning based on the training set; and using the trained metric learning model to control the dynamic mechanical system or another dynamic mechanical system.
Patent WO-2022216989-A1 (WO)
Title: Methods for manufacturing an electrochemical sensor for effective diagnostic oligonucleotide detection
Inventor: HOLDEN DERIC
IPC: H01L27/092
Filed: 2022-04-07
Abstract: The present invention features methods for manufacturing an electrochemical sensor for detecting a diagnostic target oligonucleotide. The methods described herein provide for an electrochemical sensor with a higher level of coverage of the probes on its surface, thus allowing for more sensitive detection of a target oligonucleotide. The methods may feature first mixing disulfide terminated oligonucleotides having a free thiol moiety at the 3' end with a gold substrate and subsequently introducing to the gold substrate a composition for reducing thiol moieties to cause the oligonucleotides to bind to the surface of the gold substrate. In some embodiments, the method comprises removing excess thiol and oligonucleotides, which may help with non-competitive binding. In some embodiments, the method comprises rinsing the gold substrate with water and drying with nitrogen.
Patent WO-2022232089-A1 (WO)
Title: High efficacy cu-based anti-microbial films and substrates and methods of making the same
Inventor: ANTONY ANDREW CHARLES
IPC: C08K3/015
Filed: 2022-04-26
Abstract: A method of forming an antimicrobial film, including providing a substrate with a polymer coating disposed thereon, the polymer coating including: an antimicrobial material, an inner surface contacting the substrate, and an outer surface opposite the inner surface; and extracting ions from the antimicrobial material toward the outer surface, such that the outer surface interacts with surface microorganisms. A composition, including a polymer; an antimicrobial material; and at least one of an organic solvent and an additive. The antimicrobial material comprises at least one of copper-containing glass particles, copper oxide particles, copper metal particles, copper salts, copper coordination complexes, cuprite crystals, and a combination thereof. Further, the additive can be selected to increase the oxidation resistance of the antimicrobial material.