baber/WOPTO huggingface dataset:
Patent CA-3174359-A1 (CA)
Inventor: MENEZ YANN
IPC: E04H4/12
Filed: 2021-03-25
Abstract: The invention relates to a method for replacing water in a swimming pool filtration circuit. The water replacement method implements the following steps: - measuring the previous quantity of water replaced in the swimming pool filtration circuit (2); and - measuring a cleanliness parameter (C) of the water in the filtration circuit (2); then - replacing a quantity of water (VRj) in the filtration circuit (2), in proportion to the value of a product of the previous quantity of water (VRj-1) replaced in the filtration circuit (2) and an adjustment factor (Cj), the adjustment factor being a ratio between the measured cleanliness parameter (C) and a cleanliness parameter reference value.
Patent CA-3174943-A1 (CA)
Inventor: JACOBY KYLE
IPC: G01N33/50
Filed: 2021-04-23
Abstract: Methods of detecting the efficacy and presence of a biologic drug which uses one or more 2A peptide in its manufacture and/or final pharmaceutical formulation.
Patent CA-3178179-A1 (CA)
Title: Scanner longitudinal et circonferentiel a ultrasons
Inventor: COOPER LUIS
IPC: G01N29/26
Filed: 2021-03-31
Abstract: L'invention concerne un dispositif de balayage. Le dispositif de balayage comprend une ossature dotée d'une première partie et d'une seconde partie couplée de manière pivotante à la première partie d'ossature. Le dispositif de balayage est également doté d'un premier ensemble de roues couplé à la première partie d'ossature et un second ensemble de roues couplé à la seconde partie d'ossature. De plus, le dispositif de balayage est doté d'un rail disposé de façon mobile sur la première partie d'ossature qui comprend une goulotte et un rail ainsi qu'un bras de rail couplé à la goulotte. Le dispositif de balayage est doté d'un ensemble capteur qui comprend des fourches de capteur, un capteur couplé aux fourches de capteur et un bras de capteur. Le bras de capteur est couplé aux fourches de capteur et au bras de rail. De plus, le capteur est réglable entre une première position et une seconde position par l'intermédiaire du rail.
Patent CA-3180579-A1 (CA)
Title: Amelioration de la performance acoustique d'un poteau de cloison
Inventor: SOBEL KENNETH
IPC: E04B2/74
Filed: 2021-06-01
Abstract: La présente invention concerne un ensemble de charpente comprenant un agencement de charpente acoustique et une pluralité de rails. L'agencement de charpente acoustique interconnecte un rail supérieur avec un rail inférieur. L'agencement de charpente acoustique comprend une paire de poteaux positionnés dans une configuration dos à dos et reliés mécaniquement pour former un espace entre la paire de poteaux et positionner les poteaux dans une configuration décalée pour améliorer les performances acoustiques de poteaux de cloison.
Patent CA-3181612-A1 (CA)
Inventor: LASKAR WILLIAM JOSEPH
IPC: C12Q1/68
Filed: 2022-11-10
Abstract: A wheat variety designated 6PDLPOOB, the plants and seeds of wheat variety 6PDLPOOB, methods for producing a wheat plant produced by crossing the variety 6PDLPOOB with another wheat plant, and hybrid wheat seeds and plants produced by crossing the variety 6PDLPOOB with another wheat line or plant, and the creation of variants by backcrossing, mutagenesis or transformation of variety 6PDLPOOB  are disclosed. Methods for producing other wheat varieties or breeding lines derived from wheat variety 6PDLPOOB and to wheat varieties or breeding lines produced by those methods are also provided.
Patent CA-3183037-A1 (CA)
Inventor: THOMPSON DENNIS GEORGE
IPC: A01C7/20
Filed: 2022-12-01
Abstract: A penetration depth control and gauge wheel contact force monitoring system for a row unit includes a penetration depth actuator configured to drive a gauge wheel arm assembly to move a gauge wheel relative to a row unit frame to control a penetration depth of an opener of the row unit. The penetration depth actuator includes a contact force sensor configured to output a sensor signal indicative of a contact force between the gauge wheel and a soil surface, the penetration depth actuator includes a body configured to be coupled to one of the frame or the gauge wheel arm assembly, the penetration depth actuator includes an actuating device configured to be coupled to the other of the frame or the gauge wheel arm assembly, and the actuating device is configured to move relative to the body to drive the gauge wheel arm assembly to move the gauge wheel.
Patent CA-3184310-A1 (CA)
Title: Novel phthalate-free isocyanurate composition and use thereof
Inventor: AUGUSTIN THOMAS
IPC: C08G18/79
Filed: 2021-05-21
Abstract: The present invention relates to new low-monomer, low-viscosity, low-volatility compositions of isocyanate group-containing isocyanurates and a phthalate-free plasticizer, which, when used as adhesion promoters, result in improved adhesion, to coating agents on the basis of plasticized PVC and to coated substrates.
Patent CA-3185136-A1 (CA)
Title: Partial oxidative coupling catalyst and olefin production device and olefin production method using catalyst
Inventor: YUKUMOTO ATSUHIRO
IPC: C07C11/04
Filed: 2021-09-16
Abstract: This partial oxidation coupling catalyst has a structure such that a component represented by M2ZrO3 is supported on a support, in which M represents an alkali metal.
Patent CA-3186416-A1 (CA)
Title: Methods of treating chemotherapy induced neutropenia using fixed doses of g-csf protein complex
Inventor: BARRETT JOHN A
IPC: A61K31/337
Filed: 2021-07-13
Abstract: This disclosure provides a method of preventing, alleviating, or treating a condition (i.e., neutropenia) in a patient in need thereof, the condition characterized by compromised white blood cell production in the patient. The method includes administering to the patient a therapeutically effective amount of a protein complex comprising a modified human granulocyte-colony stimulating factor (hG-CSF) covalently linked to an immunoglobulin Fc region via a non-peptidyl polymer at a fixed dose regardless of the patient's weight.
Patent CA-3188235-A1 (CA)
Inventor: MONAHAN JUSTIN
IPC: G06Q40/00
Filed: 2021-08-06
Abstract: Disclosed herein are systems and methods that provide improved list trading functionality for the mortgage origination sector. The system includes dealer software that provides at least one of a carry calculator configured to calculate a carry valuation of a bond based on predetermined data; a weighted average matrix functionality configured to calculate a single weighted average bid/offer for a group of bonds; a price matrix that allows users to quote in spread and compute an all-in dollar price bid; an axe indicator for dealers to indicate in real time if a quote is axed; and shared views allowing multiple users across trading and sales to view the inputs of other users in real time.
Patent CA-3188501-A1 (CA)
Inventor: GOLUB TODD
IPC: A61P35/00
Filed: 2021-08-09
Abstract: La présente invention concerne de manière générale l'inhibition de l'exportation de phosphate médiée par XPR1 : KIDINS220 pour traiter le cancer, en particulier, les cancers de l'ovaire et de l'utérus. La présente invention concerne également de manière générale la détermination de la dépendance du cancer à l'exportation de phosphate par détection de l'expression de SLC34A2. L'invention concerne également des compositions pour inhiber l'exportation de phosphate médiée par XPR1 : KIDINS220.
Patent CA-3189457-A1 (CA)
Title: Cristal de compose pyrimidine
Inventor: NAKAMURA HIROYUKI
IPC: C12N15/12
Filed: 2021-07-14
Abstract: L'invention fournit un cristal de 7-((3R,5S)-1-acryloyle-5-méthylpyrrolidine-3-yl)-4-amino-6-(cyclopropyléthynyl)-N-((R)-1-phényléthyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide(composé(I)), et un cristal avec un acide de celui-ci (cristal de sel ou co-cristal). L'invention concerne également un cristal de type II avec un équivalent d'acide fumarique du composé (I), dans lequel cristal un angle de diffraction (2?±0,2°) présente un pic caractéristique pour au moins trois valeurs choisies parmi 5,5°, 6,8°, 9,3°, 13,4°, 15,3°, 16,3°, 18,5°, 19,8°, 22,0° et 24,5, dans un spectre de diffraction de rayons X sur poudres. L'invention concerne aussi un cristal de type II (de forme libre) du composé (I), lequel cristal présente un pic caractéristique pour au moins trois valeurs choisies parmi 8,3°, 14,8°, 17,3°, 18,0°, 19,1°, 20,3°, 21,0°, 22,5°, 23,0° et 26,2°, dans un spectre de diffraction de rayons X sur poudres. En outre, l'invention concerne un cristal de type I (de forme libre) du composé (I), lequel cristal présente un pic caractéristique pour au moins trois valeurs choisies parmi 9,9°, 11,7°, 13,2°, 17,7°, 18,1°, 18,8° et 20,8°, dans un spectre de diffraction de rayons X sur poudres. De plus, l'invention concerne un cristal de type V avec un équivalent d'acide fumarique du composé (I), lequel cristal présente un pic caractéristique pour au moins quatre valeurs choisies parmi 6,9°, 9,4°, 10,2°, 13,7°, 21,1°, 23,6° et 26,5°, dans un spectre de diffraction de rayons X sur poudres. Enfin, l'invention concerne un cristal de type I avec un équivalent d'acide fumarique du composé (I), lequel cristal présente un pic caractéristique pour au moins quatre valeurs choisies parmi 6,4°, 10,3°, 12,8°, 15,0°, 20,7°, 23,4° et 26,6°, dans un spectre de diffraction de rayons X sur poudres.
Patent CA-3191363-A1 (CA)
Inventor: MOUNIR ZINEB
IPC: A61K31/497
Filed: 2021-09-07
Abstract: L'invention concerne une polythérapie impliquant un inhibiteur sélectif de la protéine kinase C et un inhibiteur de cMET, qui est utile pour traiter le mélanome uvéal métastatique et d'autres maladies prolifératives, telles qu'une tumeur présentant une mutation GNAQ ou GNA11. La polythérapie peut être administrée par un produit pharmaceutique, un procédé de traitement ou un kit. La polythérapie peut impliquer l'utilisation d'un inhibiteur de la protéine kinase C et d'un inhibiteur de cMET. L'invention concerne également des procédés utiles pour sélectionner des patients ou pour orienter une cure thérapeutique. Dans divers exemples, la protéine kinase C peut présenter la structure selon la formule II.
Patent CA-3191825-A1 (CA)
Inventor: CHAVEZ ALEJANDRO
IPC: C12N15/55
Filed: 2014-11-19
Abstract: Methods of making deletion mutants of Cas9 proteins and making chimeric Cas9 proteins are described. The Cas9 N- and C-terminal domains may play critical roles in crRNAitracrRNA  binding and/or PAM selectivity. To analyze activity, a series of domain exchange mutants between NM and STI (Streptococcus thermophilus Cas9) were made, replacing the N and/or C terminus of NM (Neisseria meningitides Cas9) with the homologous region from STI. The chimeric proteins were then tested using the transcriptional reporter assay described herein altering the guideRNA  and/or Cas9 specific PAM within the reporter to determine the influence of the domain exchanges on protein specificity. None of the N- terminal domain swaps between NM and STI endowed NM  with novel properties. The C-terminal exchange generated a NM-STI hybrid that was capable of interacting with the STI crRNAitracrRNA complex and was further able to suppress a reporter with a STI specific PAM.
Patent CA-3193131-A1 (CA)
Inventor: TATTAM EDWIN FRANCIS
IPC: F25D3/14
Filed: 2021-08-26
Abstract: The present invention relates to the field of the transportation and storage of thermally labile goods such as pharmaceuticals, and to a container system and apparatus employing a total loss evaporation agent such as dry ice. In particular, but not necessarily restricted thereto, the present invention relates to a system for the transportation and temperature controlled storage of ultra-low temperature, low volume, high value goods.
Patent CA-3194935-A1 (CA)
Inventor: PALMER EDWARD JOHN FRANCIS
IPC: A01B69/04
Filed: 2023-03-16
Abstract: There is disclosed a mobile autonomous agricultural system comprising a powered mobile unit, two distance sensors, an attitude sensor, a path determination module and a controller. The powered mobile unit extends frorn a front end to a back end along a longitudinal axis, and is configured for carrying agricultural equipment and to move along rows of posts along the longitudinal axis. The powered mobile unit comprises a chassis supported by wheel units, each wheel unit comprising a wheel with a suspension assembly. The suspension assembly comprises a suspension unit comprising passive spring around a shock absorber coupled to the wheel, and a linear actuator configured to move the suspension unit relative to the chassis of the mobile unit to thereby move the wheel relative to the chassis independently of the suspension unit. The two distance sensors are disposed on the powered mobile unit, and each configured to sense external objects within two dimensions and the distance of the external objects from the respective distance sensors in opposing front and back directions along the longitudinal axis. The attitude sensor is configured to determine the attitude of the powered mobile unit with respect to the horizontal. The path determination module is configured to: receive distance signals from the distance sensors, identify a row of posts based on the distance signals; and generate a motion trajectory, based on the identified row of posts, for the powered mobile unit to follow.  The controller is configured to control the linear extension of the linear actuator of the suspension assembly and the direction of travel of the mobile unit based on the motion trajectory of the path determination module and an output of the attitude sensor, to follow the row of posts and to maintain a horizontal attitude of the powered mobile unit whilst maintaining contact of the wheels with the ground.
Patent CA-3195206-A1 (CA)
Title: Appareil de cuisson combine portable
Inventor: SMITH KEVIN L
IPC: F24B1/20
Filed: 2020-10-28
Abstract: Dans un mode de réalisation, l'invention concerne un appareil de cuisson combiné portable qui a une unité pliable ayant au moins quatre parois, une partie supérieure et un fond qui sont tous accouplés mécaniquement ensemble. La partie supérieure comprend une rainure pour évacuer des éléments indésirables tels que de la graisse à partir d'une surface de cuisson. D'autres modes de réalisation sont également décrits.
Patent CA-3195244-A1 (CA)
Title: Methods and systems for making an optical functional film
Inventor: HSU ROGER WEN YI
IPC: G02B1/10
Filed: 2020-09-30
Abstract: Methods and apparatus are provided for eyeglass lens made using a solution casting process. The method may include providing a first soluble polymer solution. The method may include providing a first dye solution including at least one dye. The method may include adding the first dye solution to the first soluble polymer solution to form a first dyed solution. The method may include casting the first dyed solution to form a first film. The method may include providing a second soluble polymer solution. The method may include providing a second dye solution comprising at least one dye. The method may include adding the second dye solution to the second soluble polymer solution to form a second dyed solution. The method may include casting the second dyed solution onto the first film to form a two-layer film. The method may include laminating or casting the two- layer film to the eyeglass lens.
Patent CA-3196358-A1 (CA)
Title: Procede de production d'un complexe de zirconium radioactif
Inventor: TAKEMORI HIDEAKI
IPC: A61K51/04
Filed: 2021-10-14
Abstract: La présente invention concerne un procédé qui permet de produire un complexe marqué au zirconium radioactif et qui permet d'obtenir un taux de marquage élevé dans une réaction entre un composé ligand et des ions zirconium radioactifs. Le procédé de production selon la présente invention comprend une étape destinée à provoquer une réaction entre un composé ligand et des ions zirconium radioactifs dans une solution de réaction contenant de l'eau pour provoquer la coordination des ions zirconium radioactifs. Ladite étape est mise en ?uvre dans une condition où le pH de la solution de réaction est dans une plage acide. La solution de réaction ne contient pas de solvant organique mais contient, outre le composé ligand, un composé organique soluble dans l'eau qui a, dans la structure, un ou deux groupes sulfo ou des groupes carboxy.
Patent CA-3203792-A1 (CA)
Title: Method and device for detecting defects of a strand-like product
Inventor: SIKORA HARALD
IPC: G01N21/3581
Filed: 2021-12-20
Abstract: The invention relates to a method for detecting defects of a strand-like product which is conveyed along a conveying direction, wherein terahertz radiation is emitted by at least one transmitter to the strand-like product conveyed along the conveying direction and terahertz radiation reflected by the strand-like product is received by at least one receiver, and wherein a defect of the strand-like product is deduced upon a temporary change of the terahertz radiation signal received by the at least one receiver. The invention also relates to a corresponding device.
Patent CA-3204865-A1 (CA)
Inventor: KARIN FRISK
IPC: B22F10/20
Filed: 2021-12-06
Abstract: The present invention provides an Al-based powder suitable for additive manufacture. In one embodiment the powder consists 3-5.5% by weight of Mn, 0.2-2% by weight of Zr, 0.1-1.4% by weight of Cr, 0-2% by weight of Mg, at most 0.7% of Fe and Si in total, at most 0.7% by weight of O as an inevitable impurity, and at most 0.5% other inevitable impurities, balanced with Al. The present invention also concerns an additive manufacturing method as well as an article produced by additive manufacture.
Patent CA-3207386-A1 (CA)
Inventor: VULLO DOMENICO
IPC: E04G7/12
Filed: 2022-02-04
Abstract: A support for a safety net proximate an edge of a floor of a building under construction; the support comprising a support post extending between an upper bracket and a lower bracket. According to another broad form of the present invention there is provided a method of installing a safety net proximate an exposed edge of a building under construction; the method includes the steps of: - driving securing bolts into an underside of an adjacent higher floor and into a safety net supporting floor, - securing an upper bracket and a lower bracket respectively to the securing bolts of the higher floor and of the safety net supporting floor, - securing an upper end of a safety net support post to the upper bracket and a lower end of the safety net support post to the lower bracket.
Patent CA-3209030-A1 (CA)
Inventor: CHEN HAO
IPC: A01H5/12
Filed: 2022-02-25
Abstract: Provided herein are systems and methods for enhancement of polyphenols, such as chlorogenic acids, chicoric acid, anthocyanins, and water-soluble quercetin derivatives, production in red lettuces. Also provided are transgenic lettuce for the production of polyphenols. Also provided are parts of such transgenic lettuces, such as seeds leaves, and extracts. The disclosure also provides methods of using the new lettuces and parts thereof for protection against viral/bacterial infection (i.e., by inhibiting activities of COVID-19 virus/enzymes) diabetes, cardiovascular diseases, memory and eyesight loss, inflammation, and cancer.
Patent CA-3213110-A1 (CA)
Inventor: MCGRATH LARA LEWIS
IPC: A61K39/395
Filed: 2022-03-09
Abstract: L'invention concerne des méthodes de traitement du cancer et des méthodes de sélection d'approches pour le traitement du cancer.
Patent CA-3214590-A1 (CA)
Inventor: HARLOW RICHARD
IPC: B65D55/14
Filed: 2022-03-23
Abstract: A container closure assembly comprising: a container neck (10); a cap (6) adapted to removably engage with the container neck (10), the cap (6) arranged to close an opening (12) of the container neck (10) when engaged therewith; one or more movable elements (14a, 14b, 14c), the movable elements arranged to provide a selective engagement between the container neck (10) and the cap (6). The one or more movable elements (14a, 14b, 14c) have one or more graphical indicia (16) thereon to form at least part of at least one decoy pattern. The one or more movable elements (Mas, 14b, 14c) have a locked configuration in which the cap (6) is engaged with the container neck (10) and the decoy pattern is complete. The one or more movable elements (14sa, 14b, 14c) have an unlocked configuration in which the cap (6) is disengaged from the container neck (10) and the decoy pattern is not complete. A container comprising the container closure assembly, a cap for a container, a container comprising the cap and a storage vessel are also disclosed.
Patent CA-3214828-A1 (CA)
Title: Fluid control system for an implantable inflatable device
Inventor: GILDEA JOHN
IPC: A61F2/00
Filed: 2022-03-23
Abstract: An implantable fluid operated device may include a fluid reservoir configured to hold fluid, an inflatable member, and a pump assembly configured to transfer fluid between the fluid reservoir and the inflatable member. The pump assembly may include one or more fluid pumps and one or more valves. The one or more valves may be normally open valves, normally closed valves, or a combination thereof. One or more sensing devices may be positioned within fluid passageways of the fluid operated device. The electronic control system may control operation of the pump assembly based on fluid pressure measurements and/or fluid flow measurements received from the one or more sensing devices. Variable voltage can be applied to the control of the pump and/or the valves based on varying atmospheric conditions and the fluid pressure and/or flow measurements processed by the electronic control system.
Patent CA-3215387-A1 (CA)
Title: Utilisations d?inhibiteurs heterocycliques d?erk1/2
Inventor: Xuan Dawei
IPC: A61P35/04
Filed: 2022-04-14
Abstract: La présente invention concerne l?utilisation d?inhibiteurs hétérocycliques d?ERK1/2 pour traiter le cancer, spécifiquement des tumeurs solides. En particulier, l?inhibiteur d?ERK1/2 est le (S)-N-(2-amino-1-(3-chloro-5-fluorophényl)éthyl)-1-(5-méthyl-2-((tétrahydro2H-pyran-4-yl)amino)pyrimidin-4-yl)-1H-imidazole-4-carboxamide qui est administré à un sujet deux fois par jour, une fois par semaine et qui est utilisé pour traiter les cancers comprenant le cancer du poumon non à petites cellules (NSCLC), le mélanome, le cancer du pancréas, ou le cancer colorectal (CRC). Dans certains modes de réalisation, le cancer est une pan-tumor MAPKm/MAPKi-naïve.
Patent CA-3216228-A1 (CA)
Inventor: ENGLISH HEJIAO
IPC: C07K16/28
Filed: 2022-06-06
Abstract: Single-domain shark variable new antigen receptor (VNAR) monoclonal antibodies that specifically bind programmed death-ligand 1 (PD-L1) are described. The PD-L1-specific VNAR antibodies are capable of binding PD-L1-expressing tumor cells from human, mouse and canine origin. Immune cells expressing chimeric antigen receptors (CARs) developed using the VNAR antibodies can be used to kill PD-L1-positive tumor cells, for example in animal models of liver cancer and breast cancer.
Patent CA-3217369-A1 (CA)
Inventor: CYGAN RANDALL
Filed: 2015-12-03
Abstract: Methods and systems for estimating conductivity of clay mineral systems, and for applying the estimates in larger-scale analysis. Conductivity of the clay may be estimated by constructing a molecular model of an anhydrous charge-neutral clay, and then assigning a charge density by substitution of ions in the model of the clay structure. Counterions are inserted for charge neutrality, and water molecules are added to the model to reflect a selected level of hydration. Following assignment of force-field coefficients, molecular dynamics simulation provides data from which diffusion coefficients can be estimated. Application of the Nernst-Einstein relationship to the diffusion coefficients of the counterions provides the ion conductivity of the clay system. This conductivity can be used to derive a formation factor, and can be applied in direct numerical simulation analysis.