baber/WOPTO huggingface dataset:
Patent DE-68914050-D1 (DE)
Inventor: FAYOLLE FRANCOISE
IPC: C12P7/52
Filed: 1989-06-19
Granted: 1994-04-28
Abstract: A process is described for producing, in a reaction zone, a mixture of organic acids or of the corresponding salts containing a major proportion of n-butyric acid or of its corresponding salt, by fermenting an initial reaction mixture containing a sugar substrate in the presence of at least one strain belonging to the Clostridium species. According to the invention the following stages are carried out: a) the strain is fed with the substrate at an initial concentration of between 1 and 80 g of substrate per litre of initial reaction medium, b) the substrate concentration is allowed to decrease by at least 20% of its initial value and to a value such that it is between 0 and 30 g of substrate per litre of initial reaction medium, c) the strain is fed with the said substrate at a rate of between 0.01 and 25 g per litre of initial reaction medium and per hour and such that the residual concentration of the said substrate during the feeding period is not more than 80 g/l of initial reaction medium, and d) the mixture of acids or of salts thus produced is recovered. o
Patent DE-68916900-D1 (DE)
Inventor: URRY DAN
IPC: A61L27/22
Filed: 1989-04-05
Granted: 1994-08-25
Abstract: A method of stimulating chemotaxis toward a prosthetic device is disclosed, which method comprises incorporating a chemotactic peptide of the formula B1-X-(AGVPGLGVG)n-(AGVPGFGVG)m-Y-B2 wherein A is a peptide-forming residue of L-alanine; P is a peptide-forming residue of L-proline; G is a peptide-forming residue of glycine; V is a peptide-forming residue of L-valine; F is a peptide-forming residue of L-phenylalanine; L is a peptide-forming residue of L-leucine; B1 is H or a biocompatible N-terminal group; B2 is OH, OB3 where B3 is a non-toxic metal ion, or a biocompatible C-terminal group; X is GVPGFGVG, GVPGLGVG, VPGFGVG, VPGLGVG, PGFGVG, PGLGVG, GFGVG, GLGVG, FGVG, LGVG, GVG, VG, G or a covalent bond; Y is AGVPGFGV, AGVPGLGV, AGVPGFG, AGVPGLG, AGVPGF, AGVPGL, AGVPG, AGVP, AGV, AG, A or a covalent bond; n is an integer from 0 to 50; m is an integer from 0 to 50; with the proviso that when both n and m are O, X and Y are selected so that the chemotactic peptide has at least 3 amino acid residues in the X and Y positions combined; into a surface of a prosthetic device. Prosthetic devices which have the property of enhancing invasion of fibroblasts and endothelial cells as a result of the chemotactic peptide are also disclosed.
Patent DE-68919957-D1 (DE)
Inventor: SHINOTSUKA HIROMI
IPC: B65H1/26
Filed: 1989-09-07
Granted: 1995-01-26
Abstract: The invention relates to an apparatus for storing and supplying sheet-like materials in which a multiplicity of uniform sheet-like materials supplied are temporarily stored in a pile and then, removed one by one for transferring to the next step of procedure. The apparatus comprises guide members (6,7,8,9) for guiding the sheet-like materials; collecting and moving means (1) for transferring sheet-like materials; support members (11) wherein sheet-like materials can be loaded for downward transfer to a lower position; pile setting means (21) provided beneath said collecting and moving means (1); pressing-down means (31) for pressing the sheet-like materials downward with its own weight, provided beneath said collecting and moving means (1) and above the setting members (21); and pulling infeed means mounted beneath said setting means (21) and having vertically movable suction sections (41) for pulling the sheet-like materials one by one outward from said setting means (21).
Patent DE-68928168-D1 (DE)
Inventor: KAMIN RALPH
IPC: G01N27/30
Filed: 1989-04-28
Granted: 1997-08-14
Abstract: A method and apparatus for conducting electrochemiluminescence (ECL) measurements which control the initial conditions relating to the surface state of a triggering working electrode by reproducibly creating and maintaining a favorable surface condition so as to enhance the precision and detection limit of the measurements. Assays are performed with ECL detection in a flow-through cell environment and the precision and detection limit are enhanced by alternating initialization and measurement steps.
Patent DE-69002569-D1 (DE)
Inventor: BEAUMONT LAURENT
IPC: A23N15/00
Filed: 1990-09-19
Granted: 1993-09-09
Abstract: Machine for shredding salad, characterised in that it comprises means (5) for holding the salad in the suspended state, cutting means (9, 12, 16, 17, 20) and means (3) for driving the holding means in rotation around the axis of suspension of the salad in order to cut the salad when it is driven in rotation on itself in the suspended state. <IMAGE>
Patent DE-69005641-D1 (DE)
Inventor: ELEY CRISPIN
IPC: B01J13/02
Filed: 1990-10-26
Granted: 1994-02-10
Abstract: Dehydrated lipid bilayer vesicles are reconstituted with a liquid aqueous phase at a temperature of less than 15  DEG C.
Patent DE-69006677-D1 (DE)
Inventor: SANTICCHI AUGUSTO
IPC: B65G47/61
Filed: 1990-10-02
Granted: 1994-03-24
Abstract: This invention relates to an automatic machine for lifting, transferring and unloading clothes-hangers between two adjacent overhead conveyor lines, operating in both directions and fitted with a device for opening out the clothes on one of the conveyor lines so as to facilitate unloading the incoming clothing items between the lines. The machine consists of a trolley (2) sliding on horizontal runners. A clip (11) is fitted to the trolley for grasping the hanger hook. This clip translates vertically - for unloading and loading - or rotates up to 180 DEG  around a vertical axis up - for tipping over the hanger hook before it is unloaded.
Patent DE-69020740-D1 (DE)
Inventor: BEAMES DOUGLAS MACLEOD
IPC: E04G21/26
Filed: 1990-10-15
Granted: 1995-08-10
Abstract: A method of constructing a wall in which hollow units analogous to blocks are built up in overlapping superimposed courses, each unit having two spaced parallel vertical panels (10) or skins of rectangular form, the units being held by concealed fastening members (11); characterized in that each panel (10) has edge grooves (12, 13) extending along its upper and lower horizontal surfaces to be contiguous with those of adjacent panels, and each fastening member (11) has a body portion (17) to extend between spaced panels (10), the ends of the body portion (17) each having hook portions (20) extending upwards and downwards respectively into adjacent grooves (12, 13) of the panel edges, while said body portion (17) between adjacent panels has two upper lugs (18) extending into contact with respective upper panels, and two lower lugs (19) extending down and into contact with respective spaced lower panels, the fastening member (11) constituting a one-piece connector and spacing member.
Patent DE-69030579-D1 (DE)
Inventor: GILLIES STEPHEN
IPC: C12R1/91
Filed: 1990-08-01
Granted: 1997-05-28
Abstract: Disclosed are methods of producing fusion proteins including those with dual biological activities. These methods include the provision of first and second DNA sequence encoding a first and second polypeptide, respectively, the digestion of the first DNA sequence at a restriction site adjacent its 5' terminus, and the ligation of a linker/adapter sequence (1/a) to the restricted end of the first DNA sequence, thereby forming a cassette. The 1/a includes, at one end, that portion of the first DNA sequence extending from its terminus nearest the restriction site to the restriction site, and at the other end, one side of a splice site. A eucaryotic host cell is transfected with the cassette and the second DNA sequence having, at one end, one side of a splice site compatible with the side of the splice site on the 1/a. The transfected host cell is cultured to express the transfected DNA as a single chain fusion protein. <IMAGE>
Patent DE-69100922-D1 (DE)
Inventor: SCHWOB HANS RUDOLF
IPC: A47K5/12
Filed: 1991-05-10
Granted: 1994-02-17
Abstract: It comprises a lower part (1) and an upper part (2). The lower part (1) comprises a body (4) housing the metering and expulsion device for the product. A package (3) containing the product is arranged in a housing (5) which communicates with a lower chamber (7). The chamber (7) is in communication with a first chamber (8). One end of a piston (11) is displaced in a leaktight manner inside the chamber (8). The hollow piston (18) is closed at its second end by a screwed plug (16) emerging into a bore (17). The bore (17) ends in a tubular projection (22) capped by a sleeve (23) whose lower end is equipped with a slot (24). A lever (25) articulated about a pin (26) is connected to the hollow piston (11). The tubular projection (22) is equipped with a countersunk part (27) and in the same horizontal plane the dispenser is equipped with a horizontal extension (28). At the end of the expulsion phase, the projection (28) crushes the sleeve (23) which reassumes its initial shape during the return phase, creating a reduced pressure in the sleeve (23) permitting suction of the drop of product remaining outside. <IMAGE>
Patent DE-69106571-D1 (DE)
Inventor: KORB KLAUS
IPC: E05C9/02
Filed: 1991-02-28
Granted: 1995-02-23
Abstract: The drive rod lock, actuated by a lock cylinder, has a gear ring enclosing the tongue of the cylinder, contg. a gap through which the cylinder passes. The ring meshes on the outside with two pinions, coupled via redn. gear trains to slides actuating the rods. All gears and pinions are carried on a mounting plate (37) between the top and bottom of the lock housing (2).
Patent DE-69110899-D1 (DE)
Inventor: HEIJMAN MARINUS
IPC: B62K1/00
Filed: 1991-10-18
Granted: 1995-08-03
Abstract: PCT No. PCT/NL91/00207 Sec. 371 Date Apr. 1, 1993 Sec. 102(e) Date Apr. 1, 1993 PCT Filed Oct. 18, 1991 PCT Pub. No. WO92/06885 PCT Pub. Date Apr. 30, 1992.A one-wheeled vehicle has a spokeless hoop, a rigid load carrier mounted inside the hoop and a seat. The carrier forms a connection between a plurality of guide elements rotatably connected with the carrier and distributed along the circumference of the hoop. The guide elements guide the hoop with respect to the carrier during the rolling movement of the hoop. The vehicle is controlled purely through the rider shifting weight.
Patent DE-69119607-D1 (DE)
Inventor: PLYLEY ALAN
IPC: A61B17/072
Filed: 1991-11-12
Granted: 1996-06-20
Abstract: The present invention provides a staple cartridge assembly adapted for use in a surgical stapler having a cartridge retention portion and an anvil portion which are movable between a closed position and an open position. The cartridge assembly comprises (1) a firing assembly for firing staples which is movable between a pre-fired and a fired position, (2) a safety member, (3) means mounting the safety member on the cartridge assembly for movement between a free-movement position which affords movement of the cartridge retention portion and the anvil portion between the open and closed position and a blocking position which prevents the cartridge retention portion and the anvil portion from being moved to the closed position, and (4) means for releasably retaining the safety member in the free-movement position and for releasing the safety member to afford movement of the safety member toward the blocking position when the firing assembly is moved from the pre-fired to the fired position such that upon movement of the cartridge retention portion and anvil portion to the open position, the safety member prevents the cartridge portion and the anvil portion from thereafter being moved to the closed position while the stapler is loaded with the spent cartridge.
Patent DE-69123249-D1 (DE)
Inventor: ORGAIN PETER
IPC: A61M5/32
Filed: 1991-05-16
Granted: 1997-01-02
Abstract: A reusable arrangement to protect against accidental contact with the sharp surfaces of needles and other invasive medical instruments. In one embodiment, the invention comprises a collar that engages a sharp surgical instrument in advance of its sharp end. Attached to the collar by means of a hinge is a slotted longitudinal member, which swings over the sharp end of the instrument, thereby engaging either the collar or the portion of the instrument just in front of the collar and also retaining the instrument behind a keeper shelf. The keeper shelf may be engaged with the opposite side of the longitudinal member to lock this member over the sharp instrument. The longitudinal member may also be equipped with wing members to facilitate movement of the sharp instrument around the keeper shelf. In another embodiment, the locking mechanism comprises a set of flanges depending from the longitudinal member that are gripped by complementary catches on the collar when the device is placed into the closed position.
Patent DE-69128253-D1 (DE)
Inventor: RING DAVID
IPC: C12Q1/68
Filed: 1991-09-24
Granted: 1998-01-02
Abstract: This invention relates generally to the field of immunology, in particular that of antibodies and antibody productions. More specifically, this invention relates to bispecific antibodies, the hybrid hybridomas which produce them, the parent hybridomas, the production and selection of the hybridomas and hybrid hybridomas, and the purification of the bispecific antibodies. Specific examples relate to bispecific monoclonal antibodies which recognize both the human multi-drug resistance antigen, P-glycoprotein and human Fc gamma  receptor III (hFc gamma RIII. These bispecific antibodies are useful in killing cancer cells.
Patent DE-69202384-D1 (DE)
Inventor: AHLUND BENGT
IPC: B25B13/46
Filed: 1992-03-27
Granted: 1995-06-14
Abstract: A ratchet wrench comprises a handle (2) in which a ratchet spring (1) extends axially between the wrench head at one end of the handle and a gripping sleeve (4) at the other end thereof. The gripping sleeve carries a rotatable or twistable resetting sleeve (3) by means of which the ratchet spring can be adjusted between two predetermined positions so as to activate a ratchet device mounted in the wrench head. The ratchet spring has a hairpin-like bend whose one leg (22) engages the resetting sleeve while the other leg (21) thereof can be snapped around a shoulder (8) located on the bottom of an operating chamber (7) located within the gripping sleeve. The axial extension of the other leg finds correspondence in the crank (11) formed by the ratchet spring in the transition to the wrench head. The crank engages in and adjusts the ratchet device, thereby enabling the direction in which the ratchet wrench can return freely to be reversed. <IMAGE>
Patent DE-69208556-D1 (DE)
Inventor: SHIELDS CHARLES JOHN
IPC: B01J20/18
Filed: 1992-07-02
Granted: 1996-04-04
Abstract: A process for the removal of 1-chloro-2,2-difluoroethylene from 1,1,1,2-tetrafluoroethane by contacting the mixture with a zeolite having a mean pore size in the range of 3.5 ANGSTROM  and 4.8 ANGSTROM  and having potassium as counter cation. The zeolite having potassium as counter-cation may be produced by cation-exchange with a commercially available zeolite, for example AW-500. <IMAGE>
Patent DE-69221869-D1 (DE)
Inventor: THILL FRANCIS
IPC: C09K3/30
Filed: 1992-06-15
Granted: 1997-10-02
Abstract: A preferred method of producing an aqueous, stable double emulsion is disclosed. The first step of the method is the production of an "inner" emulsion. The inner emulsion is produced by combining water, a liquid hydrocarbon solvent, and an emulsifier, in an agitated mixing vessel, along with an effective amount of finely-divided particulate material, to produce an oil-in-water emulsion having a viscosity of no more than about 200,000 centipoises, wherein the finely-divided particulate material is substantially homogeneously-dispersed throughout the thus-produced oil-in-water emulsion. The second step of the method is the production of an "outer" emulsion. The outer emulsion is produced by combining a liquid hydrocarbon solvent, water, and an emulsifier, in an agitated mixing vessel, to produce a water-in-oil emulsion. The third step of the method is the production of a "dual" emulsion. The dual emulsion is produced by combining the water-in-oil emulsion with an effective amount of the oil-in-water emulsion, in a mixing zone, thereby to produce the aqueous, stable double emulsion.
Patent DE-69222888-D1 (DE)
Inventor: PHILLIPS ROBERT L
IPC: D04H1/46
Filed: 1992-05-29
Granted: 1997-12-04
Abstract: An entangled fibre nonwoven fabric containing irregular sized apertures in a random irregular nonrepeating pattern in disclosed. In the method of the invention, a fibrous web is caused to be displaced out of registry with the forming member between fluid impacts by columnar jets of water.
Patent DE-69226911-D1 (DE)
Inventor: ALBRECHT OTTO
IPC: G06T1/00
Filed: 1992-06-24
Granted: 1998-10-15
Abstract: Provide is a method for detecting defects in a film structure of a thin film formed on a substrate, comprising projecting a light flux in a direction precisely parallel or nearly parallel to the face of the substrate; separating a reflected light from the thin film and the substrate from a scattered light toward the direction precisely perpendicular or nearly perpendicular to the face of the substrate; and reading information only of the scattered light. <IMAGE>
Patent DE-69305109-D1 (DE)
Inventor: HIROSE TAKU
IPC: C09K19/30
Filed: 1993-05-24
Granted: 1996-11-07
Abstract: A liquid crystal composition comprising (1) at least one compound selected from those expressed by the formula (I) and (2) at least one compound selected from those expressed by the formulas (II), (III), (IV) and (V): <CHEM> wherein R1 to R5 are C1-10 alkyl; R6 and R7 are C1-10 alkyl or alkenyl; X is H or F; X1 and X2 are F, -CF3, -OCF3, -CHF2 or -OCHF2; Y1 and Y2 are H or F; Z1, Z2 and Z4 are -COO-, -CH2CH2-or a single bond; Z3, Z5 and Z6 are -COO-, -CH2CH2-, -C IDENTICAL C- or a aingle bond; and A is <CHEM> which composition is provided with characteristics of high specific resistance, low viscosity while keeping small current consumption, a suitable clearing point and threshold voltage.
Patent DE-69306450-D1 (DE)
Inventor: HOBLINGRE ANDRE
IPC: B60R25/022
Filed: 1993-02-23
Granted: 1997-01-23
Abstract: This assembly, including a steering shaft (1) which can move rotationally in a column body (2) including a mechanism (3) with a lock bolt (4) for guarding the vehicle against theft, which can be moved between a retracted position and an active anti-theft position, the said shaft concluding two shaft portions (5, 6), one (5) of them carrying the steering wheel, and the other (6) of them being connected to the rest of the steering mechanism of the vehicle and both shaft portions being connected by disengageable linking means (8) which can be moved, under the control of the anti-theft mechanism, between an active position for coupling the two portions of shaft and a retracted, anti-theft position for releasing the two portions of shaft from one another so that the portion of shaft (5) carrying the steering wheel is free to rotate with respect to the other portion of shaft (6), is characterised in that corresponding end zones (5a, 6a) or the portions of shaft (5, 6) are arranged one around the other and in that the disengageable linking means (8) are mounted so that they can move between the two, external and internal, portions of shaft. <IMAGE>
Patent DE-69315230-D1 (DE)
Inventor: NIELSEN ELGAARD
IPC: E05C3/16
Filed: 1993-08-18
Granted: 1997-12-18
Abstract: The snap lock is in particular for closing a window, a door or the like, and comprises a base member (10), a latch (5) having a projecting part (6) for engagement with a striking plate (4) and adapted to be displaced from a closing position against a spring power and an actuator device (12) for taking the latch (5) into a retracted opening position, wherein the latch (5) is pivotal in relation to the base member (10) about an axis transverse to the direction of said displacement, the opening position is a position turned out about said axis (7, 9), and a resilient member (19) is arranged to retain the latch (5) in a non-turned-out position parallel to the closing position. The latch (5) and the base member (10) constitute opposite members in a four-link mechanism, the latch (5) being by means of a first hinge (7) hinged at the one end comprising the projecting part (6) to a link (8) which again by means of a second hinge (9) is hinged to the base member (10), the latch (5) being hinged at its other end by means of a third hinge (11) to the actuator device (12) which again by means of a fourth hinge (13) is hinged to the base member (10).
Patent DE-69321112-D1 (DE)
Inventor: STANLEY CHRISTOPHER JOHN
IPC: C12Q1/6813
Filed: 1993-01-22
Granted: 1998-10-22
Abstract: PCT No. PCT/GB93/00147 Sec. 371 Date Nov. 18, 1994 Sec. 102(e) Date Nov. 18, 1994 PCT Filed Jan. 22, 1993 PCT Pub. No. WO93/15224 PCT Pub. Date Aug. 5, 1993A process is described for denaturing native double-stranded nucleic acid material into its individual strands in an electrochemical cell. The process is an electrical treatment of the nucleic acid with a voltage applied to the nucleic acid material by an electrode. The process employs a promoter which is an inorganic multivalent cation such as magnesium ions to speed denaturation. The process may be used in the detection of nucleic acid by hybridrising with a labelled probe or in the amplification of DNA by a polymerase chain reaction or ligase chain reaction.
Patent DE-69321909-D1 (DE)
Inventor: HECTOR RICHARD F
IPC: A61K39/395
Filed: 1993-08-16
Granted: 1998-12-10
Abstract: Bacterial meningitis infection in a mammal is treated by intravenous infusion of therapeutically effective amounts of monoclonal antibodies which bind to tumor necrosis factor alpha. Treatment can be initiated up to five hours after bacterial challenge and is preferably in combination with an antibiotic selected from cephalosporins and aminoglycosides.
Patent DE-69332356-D1 (DE)
Inventor: OLSEN HANS
IPC: B01D39/16
Filed: 1993-11-09
Granted: 2002-11-07
Abstract: PCT No. PCT/DK93/00366 Sec. 371 Date May 8, 1995 Sec. 102(e) Date May 8, 1995 PCT Filed Sep. 9, 1993 PCT Pub. No. WO94/11088 PCT Pub. Date May 26, 1994A filtration medium made from a plurality of solid fibers aligned in the same direction and packed and bundle together and compressed at a portion thereof by a retainer member, and a displacement member disposed inside the packed fibers forming close packed aligned fibers defining a fluid flow passages between the fibers having a cross-sectional area capable of retaining particles from a fluid passing therethrough.
Patent DE-69405289-D1 (DE)
Inventor: GREGOIRE JEAN FRANCOIS MICHEL
IPC: B05B11/00
Filed: 1994-05-18
Granted: 1997-10-09
Abstract: This bottle comprises:   - a rigid body (1) equipped with means (11, 13) for positioning an intermediate part (15) of the bag; - a push-cap (6, 7) which is fitted onto the body and to which is fixed, in a sealed manner, the neck (19) of the bag, this push-cap delimiting an outlet chamber (38) which includes an inlet orifice (29) in communication with the bag and an outlet conduit (31) equipped with an outlet non-return valve (8);   - a spring (9) trying to move the push-cap away from the body; and - a supply non-return valve (5) integral with a part (17) of the bag located upstream of the said inlet orifice (29) and, together with the push-cap, delimiting a chamber (37) for supplying the outlet chamber (38).   <IMAGE>
Patent DE-69405324-D1 (DE)
Inventor: BOIS HENRI GEORGES
IPC: B65B9/213
Filed: 1994-07-06
Granted: 1997-10-09
Abstract: The present invention relates to a machine for automatically forming packaging based on films (10) which are equipped with strips (12), comprising a forming neck (200), a filling chute (300), means (600) for longitudinal welding and means (700) for transverse welding, characterised in that the machine includes means (400) for localised pre-welding of the strips (12), which pre-welding means (400) are offset angularly with respect to the longitudinal welding means (600), and the machine includes means (500) for guiding the strips (12), located upstream of the pre-welding means (400). The present invention also relates to the packages thus obtained. <IMAGE>