baber/WOPTO huggingface dataset:
Patent HR-P20130697-T1 (HR)
Title: Subcutaneous anti-her2 antibody formulation
Inventor: ADLER MICHAEL
IPC: A61K39/395
Filed: 2010-07-28
Abstract: The present invention relates to a highly concentrated, stable pharmaceutical formulation of a pharmaceutically active anti-HER2 antibody, such as e.g. Trastuzumab (HERCEPTIN(TM)), Pertuzumab or T-DM1, or a mixture of such antibody molecules for subcutaneous injection. In particular, the present invention relates to formulations comprising, in addition to a suitable amount of the anti-HER2 antibody, an effective amount of at least one hyaluronidase enzyme as a combined formulation or for use in form of a co-formulation. The formulations comprise additionally at least one buffering agent, such as e.g. a histidine buffer, a stabilizer or a mixture of two or more stabilizers (e.g. a saccharide, such as e.g. alpha,alpha-trehalose dihydrate or sucrose, and optionally methionine as a second stabilizer), a nonionic surfactant and an effective amount of at least one hyaluronidase enzyme. Methods for preparing such formulations and their uses thereof are also provided.
Patent SI-1444354-T1 (SI)
Title: Method for enhancing the efficiency of an enzymatic purification process
Inventor: SUDOR JAN
IPC: C12P1/00
Filed: 2002-10-14
Abstract: This invention relates to methods for enhancing the efficiency of biological processes that involve successive enzymatic reactions. More specifically, the invention relates to methods for enhancing the efficiency of an enzymatic purification process by increasing the temperature between successive enzymatic purification steps.
Patent SI-1460969-T1 (SI)
Title: Prevention and treatment of androgen-deprivation induced osteoporosis
Inventor: STEINER MITCHELL S
IPC: A61K31/00
Filed: 2002-11-27
Abstract: This invention relates to the use of a selective estrogen receptor modulator (SERM) for the preparation of a pharmaceutical composition for treating androgen-deprivation induced loss of bone mineral density (BMD) or androgen-deprivation induced bone fractures in a male subject having prostate cancer.
Patent SI-1847534-T1 (SI)
Title: Thiadiazoline derivatives for treating cancer
Inventor: MURAKATA CHIKARA
IPC: A61K31/4439
Filed: 2002-12-11
Abstract: (wherein R 1  and R 4  are the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkynyl, substituted or unsubstituted lower alkenyl, or the like; R 5  represents a substituted or unsubstituted heterocyclic group, substituted or unsubstituted aryl, or the like; R 2  represents -C(=W)R 6  or the like; R 3  represents a hydrogen atom, -C(=W A )R 6A  , or the like)  Antitumor agents which comprises a thiadiazoline derivative represented by the aforementioned general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient are provided.
Patent SI-1546508-T1 (SI)
Title: Rock bolt post grouting apparatus
Inventor: RATAJ MIECZYSLAW STANISLAW
IPC: E21D21/00
Filed: 2003-08-01
Abstract: An apparatus ( 100 ) for post-grouting a rock bolt ( 1 ) has an elongate sleeve ( 101 ) adapted to receive a rock bolt ( 1 ) with a first end ( 1 a) thereof extending beyond the sleeve first end ( 101 a) and a second end ( 1 b) thereof extending beyond the sleeve second end ( 101 b). An end fitting ( 102 ) is attached to the sleeve second end ( 101 b) and has a central aperture ( 106, 107 ) for receiving the rock bolt ( 1 ). Grout passages ( 112 ) communicate the exterior of the end fitting ( 102 ) with the interior of the sleeve ( 101 ). A seal means ( 117 ) is displaceable between open and closed positions so as to seal the grout passages ( 112 ). The seal means ( 117 ) is biased towards the closed position at which the grout passages ( 112 ) are substantially sealed. Injection of grout into the end fitting ( 102 ) via the passages ( 112 ) deflects the seal means ( 117 ) to the open position enabling flow of grout through the passages ( 112 ) and into the sleeve ( 101 ).
Patent SI-1589966-T1 (SI)
Title: Preparation of new pharmaceutically suitable salt of losartan and forms thereof with new purification and isolation methods
Inventor: ANTONCIC LJUBOMIR
IPC: A61P9/12
Filed: 2004-01-29
Abstract: Pharmaceutically suitable crystalline and amorphous alkali and earth-alkali salts of 2-n-butyl-4-chloro-5-hidrox-ymethyl-1-[[2'-(1 H-tetrazole-5-yl)[1.1'-biphenyl]-4-yl]-1 Himidazole have been prepared and new manufacturing, purification and isolation procedure for said salts in high purity have been described. Stable pharmaceutical compositions containing new crystalline potassium salts of 2-n-butyl-5-chloro-5hidroxymethyl-1-[[2'-(1H-tetrazole-5-yl)[1.1'-biphenyl]-44-yl]-1H-imidazole have been prepared.
Patent SI-1784086-T1 (SI)
Title: Edible food container and method of making same
Inventor: VICENTINI TIZIANO
IPC: A23L1/00
Filed: 2005-09-07
Abstract: An edible food container comprises a main body ( 2 ) having a central portion for supporting food ( 3 ), at least one peripheral portion ( 4 ) extending therefrom for laterally containing food. The central portion ( 3 ) and the peripheral portion ( 4 ) are both made of the same edible material. Furthermore, the peripheral portion ( 4 ) has one or more removable areas ( 5 ) having differential mechanical strength from the central portion ( 3 ) to facilitate separation and removal of such one or more removable areas ( 5 ) by a user.
Patent SI-1802677-T1 (SI)
Title: Epoxy resins with improved elasticity
Inventor: GRASBOCK ROSEMARIA
IPC: C08G59/18
Filed: 2005-07-18
Abstract: An epoxy resin AB comprising, in its polymer chain, moieties derived from aliphatic polyethers  B1  having at least 4 carbon atoms in the alkylene group or from aliphatic polyesters  B2  based on linear, branched or cyclic aliphatic polyhydric alcohols  B21  and linear, branched or cyclic aliphatic polyvalent acids  B22,  where the average number of hydroxyl or acid groups in  B21  or  B22  is at least 1.9, a process for its preparation, and a method of use thereof to make elastic coating films that impart good corrosion resistance even in thin layers
Patent SI-1655195-T1 (SI)
Title: Apparatus and Method for displaying data of guided railbound vehicles on a terminal
Inventor: BEYER RALF
IPC: B61L15/00
Filed: 2005-10-27
Abstract: The device has a memory provided for a private internet home page and attached at each rail vehicle. The memory of the rail vehicle is connected with a terminal by a control bus for reading a home page, where the control bus is a wire or radio circuit. The terminal consists of Graphical-User-Interface and a display device for acquiring data. An independent claim is also included for a method for displaying of data of rail vehicle on a terminal of the vehicle or a control station.
Patent SI-1921956-T1 (SI)
Title: Kitchen appliance comprising a safety fixture for locking a tool coupling
Inventor: MAK MARJAN
IPC: A47J43/00
Filed: 2006-08-17
Abstract: The invention relates to an electromotive kitchen appliance (1), preferably an electromotive single-purpose or universal food processor, comprising an electric motor (3), at least one tool (17, 18), at least one tool coupling (15, 16) for joining the tool (17, 18) to the kitchen appliance (1), a safety fixture (52) for the tool (17, 18), which is assigned to the tool coupling (15, 16) and locks the tool (17, 18) in the tool coupling (15, 16) during operation of the electric motor (3), and a tool (17) that supports the safety function of the kitchen appliance (1). The invention is characterized in that the kitchen appliance is particularly reliable to operate while being safe to use.
Patent SI-1965638-T1 (SI)
Title: Sustained-release microcapsules
Inventor: MULQUEEN PATRIC JOSEPH
IPC: A01N25/04
Filed: 2006-12-22
Abstract: A product comprising microcapsules which themselves comprise (a) a polymeric shell; and (b) a core which comprises (i) a solid agrochemical dispersed in a matrix and (ii) a water-immiscible liquid characterized in that the matrix is distributed non-continuously throughout the water-immiscible liquid.
Patent SI-2009807-T1 (SI)
Title: Distributor power line communication system
Inventor: HENDERIECKX LUC
IPC: H04B3/54
Filed: 2008-03-18
Abstract: Distributor power line communication system comprising a communication server (1) sending and receiving messages over a telecommunication network (2), a power distribution substation (3) to which a power distribution network (4) towards end users (5) is connected, at least one gateway (6; 18) transferring messages from the telecommunication network (2) onto the power distribution network (4) in a predetermined frequency band, a plurality of smart metering devices (7; 17; 27) at end user mains networks for measuring power consumption and comprising a power line communication modem (8; 18) sending and receiving messages within the predetermined frequency band over the power distribution network (4), power line communication filters (10, 11) on power lines connecting the power distribution network and the end user mains networks and on power lines connecting the power distribution network to the power distribution substation, each filter blocking frequencies within the predetermined frequency band.
Patent DE-3751165-T2 (DE)
Inventor: SHOHER ITZHAK DR
IPC: B22F1/12
Filed: 1987-12-01
Granted: 1995-07-27
Abstract: The invention relates to a method and material for reinforcing a dental metal structure in forming, repairing or reinforcing a dental restoration. The reinforcing material comprises a metal composition including a substantial proportion of particles of high fusing temperature metal having a melting temperature preferably above about 1300 DEG C with such high fusing temperature metal particles being below 100 microns in size and with said composition having a minor proportion of a low fusing temperature metal which is adapted to melt upon heat treatment at a temperature below said high fusing melting temperature and preferably below 1200 DEG C. The method and material of the present invention forms a mass which retains its shape but does not suffer any shrinkage from heat treatment and is accordingly ideal for use in dental procedures where shrinkage cannot be tolerated.
Patent DE-3786592-T2 (DE)
Inventor: KNOWLES JONATHAN
IPC: C12N15/52
Filed: 1987-04-29
Granted: 1993-11-04
Abstract: A vector system for transformation of Trichoderma has been developed. The vector system can be used for high expression and secretion of proteins in Trichoderma by transformation of a suitable Trichoderma strain with the vector system comprising a gene for a desired protein.
Patent DE-3852589-T2 (DE)
Inventor: BOIGEGRAIN ROBERT
IPC: C07C229/42
Filed: 1988-08-11
Granted: 1995-08-10
Abstract: Process for the preparation of compounds of formula 
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 in which X denotes hydrogen, a halogen, a trifluoromethyl group or a lower alkyl group; W denotes methyl, Q denotes hydrogen or W and Q together form an ethylene group and R' denotes a lower alkyl group, characterised in that the amino group of the phenol corresponding to the compound of formula I is protected, the compound thus obtained is subjected to an alkylation with a compound of formula Hal-CH2-COOR', where R' is as defined in the case of formula I and Hal is chlorine, bromine or iodine, and the amino group of the product thus obtained is then deblocked.
Patent DE-3872207-T2 (DE)
Inventor: GRABIAK RAYMOND CHARLES
IPC: C02F1/72
Filed: 1988-12-27
Granted: 1992-12-10
Abstract: Waste streams from N-phosphonomethylglycine facilities are treated to remove by-products, unreacted raw materials and N-phosphonomethylglycine by heating the waste stream in the presence of a transition metal catalyst and contacting the waste stream with an oxygen-containing gas.
Patent DE-3879440-T2 (DE)
Inventor: AKLONIS CAROL ANN
IPC: A61K35/66
Filed: 1988-12-20
Granted: 1993-06-24
Abstract: Cultivation of a strain of the microorganism Dactylosporangium sp. A.T.C.C. No. 53693, yields the antibiotic substance EM5586 which contains the novel useful components dactylocycline A and dactylocycline B.
Patent DE-60004988-T2 (DE)
Inventor: YEH WEN-YA
IPC: B26B13/24
Filed: 2000-07-12
Granted: 2004-09-02
Abstract: A pair of hairdressing scissors comprises first and second scissor elements (1a and 1b; 2a and 2b) pivotally connected together, each scissor element (1a, 1b; 2a; 2b) including a blade portion (16, 18; 26, 28). The blade portion (18; 28) of the second scissor element (1b; 2b) has a cutting edge (18a; 28a). The blade portion (16; 26) of the first scissor element (1a; 2a) includes a plurality of teeth (12; 22) that are spaced by an interval (14; 24). Each tooth (12; 22) on the second scissor element (1a; 2a) includes a distal end (12a; 22a) having a first side (12b; 22b) that faces the cutting edge (18a; 28a) of the first scissor element (1b; 2b) and a second side (12c; 22c) that faces away from the cutting edge (18a; 28a). The first side (12b; 22b) of the distal end (12a; 22a) of each tooth (12; 22) includes a distal first guide face (15; 25) and a second guide face (17; 27) extended from the distal first guide face (15; 25). The distal first guide face (15; 25) has a slope smaller than that of the second guide face (17; 27). The second guide face (17; 27) includes a cutting edge (120; 220) that cooperates with the cutting edge (18a; 28a) of the second scissor element (1b; 2b) for cutting hair. A distal beveled face (121; 221) and a third guide face (122; 222) are formed between the first side (12b; 22b) and the second side (12c; 22c) of the distal end (12a; 22a). The distal beveled face (121; 221) guides hair to be cut. The guide face (122; 222) meets the first side (12b; 22b) at the cutting edge (120; 220). <IMAGE>
Patent DE-60005846-T2 (DE)
Inventor: LINDGREN FREDRIK
IPC: A61F11/14
Filed: 2000-06-20
Granted: 2004-12-30
Abstract: The present invention provides an earmuff device comprising an earmuff cup having at least a window portion which is formed of an optical material which transmits light rays in such a way that the human eye can see through the material to a degree that an earplug or other object inserted within the ear is visually perceivable to the human eye. In other words, the earmuff cup is formed of a transparent material or a translucent material so long as the earplug inserted within the wearer's ear is visually perceivable through the translucent portion of the earmuff cup. Because the earmuff cup is formed of a material that permits an individual, such as a supervisor or hearing conservationist, to perceive whether an earplug is inserted within the wearer's ear, the earmuff device of the present invention is particularly well suited for use in a dual hearing protection environment in which the previous method of compliance monitoring was time consuming and difficult.
Patent DE-60007668-T2 (DE)
Inventor: JACOBS ANTONIUS ARNOLDUS CHRIS
IPC: A61K39/09
Filed: 2000-01-20
Granted: 2004-12-02
Abstract: The present inventon relates to the use of live attenuated bacteria for the manufacture of a vaccine for submucosal administration.
Patent DE-60022041-T2 (DE)
Inventor: SVENSSON KARL GUNNAR
IPC: A47K10/38
Filed: 2000-05-18
Granted: 2006-06-08
Abstract: A device ( 1 ) for extracting one or more paper strip portions ( 3 ') from a paper strip rotatably arranged around an axle, preferably rolled around a bobbin, while utilizing an edge surface serving as a tearing edge or a scissor device, belonging to a lid part ( 6 ). Adjacent the edge surface ( 5 ) and located within or below the lid part ( 6 ) is arranged a rotatable counter roller ( 8 ), adapted to press against the paper strip ( 3 ) with part of its peripheral surface. The counter roller is rotatable by a powered feed roller ( 7 ) so that the rotation will extract a paper strip portion ( 3 ') past the edge surface. The counter roller ( 8 ) is made to press against the paper strip by a spring force. A frontal lid part ( 6 ) carries the counter roller ( 8 ) and has an edge surface or cutting edge ( 5 ).
Patent DE-60024471-T2 (DE)
Inventor: YAMASHITA TORU
IPC: C07D405/12
Filed: 2000-09-14
Granted: 2006-08-03
Abstract: This invention relates a benzopyran denvative of formula (I) wherein, R1 and R2 represent each independently a hydrogen atom, a (substituted)C1-6 alkyl group or a (substituted)phenyl group,R3 represents a hydroxyl group or C1-6 alkylcarbonyloxy group, R4 represents a hydrogen atom, or R3 and R4 together form a bond, m represents an integer of 0-4, n represents an integer of 0-4, Y is absent, or represents CR11R12 in which R11 and R12 represent each independently a hydrogen atom or a C1-6 alkyl group, R5 represents an aryl group or a (substituted)heteroaryl group,R6 represents a hydrogen atom or a C1-6 alkyl group,R7 represents a hydrogen atom or a C1-6 alkyl group,X is absent, or represents C=O or SO2, R8 represents a hydrogen atom, a (substituted)C1-6 alkyl group or C3-6 cycloalkyl group, and R9 represents a nitro group, etc., or a pharmaceutically acceptable salt thereof. And this invention also relates an antiarrhythmic agent having the prolongation effect on the functional refractory period comprising said compound or a pharmaceutically acceptable salt thereof as an active ingredient.
Patent DE-60027078-T2 (DE)
Inventor: BERGAMASCHI GIOVANNI
IPC: E06B9/90
Filed: 2000-05-03
Granted: 2007-04-19
Abstract: A mechanism for locking curtains and the like includes a sleeve rotating about a relative axis and fastened to a roll (5), in coaxial relation therewith. A curtain is rolled up on the roll (5). A barrel (6) features at least one radial housing (8) opening outside of the barrel (6) and enters freely the sleeve (3). The mechanism includes also one spring (8a) introduced freely in each radial housing (8) and pushing a cylinder or a sphere (7) against an inner surface (3d) of the sleeve (3). <IMAGE>
Patent DE-60031170-T2 (DE)
Inventor: GETLICHERMANN MICHEL
IPC: C09D195/00
Filed: 2000-11-30
Granted: 2007-08-23
Abstract: A watertight membrane for use in roofing, comprises a bituminous mass containing an olefinic polymer with intrinsic crystallinity. Membrane comprises bituminous mass containing olefinic polymer with intrinsic crystallinity. Membrane is provided with anti-exudation layer on its surface and self-adhesive layer on its reverse face. Independent claims are also included for: (1) the process of production of membrane as claimed comprising: (a) application of bituminous mass onto first fibrous cloth sheet in such way as to coat reverse face of the first fibrous cloth from underneath, while the other face is provided with anti-exudation layer; and (b) bringing second fibrous sheet in contact with bituminous mass applied onto first sheet, and coating it instantly with bituminous mass from underneath, where the latter bituminous mass can be of self-adhesive type, or self-adhesive layer can be applied onto bituminous coat; (2) bituminous mass for production of watertight membrane, containing olefinic polymer with intrinsic crystallinity; and (3) watertight membranes assembly in which each membrane comprises bituminous mass and is provided with anti-exudation coat on its surface, and where the membranes are joined by superposing along the edges in such way that they adhere to each other along the edge forming joint whose resistance is at least 50N/5 cm.
Patent DE-60103298-T2 (DE)
Inventor: BONNEBAT CLAUDE
IPC: B05C11/06
Filed: 2001-09-24
Granted: 2004-09-16
Abstract: A method for continuously coating at least one surface of a metal strip with a single-layer or multilayer crosslinkable polymer fluid film (20) obtained from solid precursors at room temperature and free of non-reactive solvent or diluent and whereof the softening temperature is higher than 50° C. The method includes: continuously unwinding the metal strip (1); preheating the metal strip (1) at a temperature substantially equal to or higher than the crosslinkable polymer softening temperature; forming by forced flow on an applicator roll (12) with deformable surface a single-layer or multilayer coat (13) of the crosslinkable polymer; driving in rotation the applicator roll in the same direction as that of the unwinding of the metal strip (1), heating the applicator roll (12) to a temperature higher than the temperature for forming the coat; and transferring the coat onto the metal strip to form the single-layer or mutilayer film (20) on the corresponding surface of the metal strip (1). Also a coating device for implementing the method.
Patent DE-60104325-T2 (DE)
Inventor: LAMBRECHT WILLY
IPC: G01M17/007
Filed: 2001-10-17
Granted: 2005-08-25
Abstract: A device with at least one upper-plate(1,2,3,4) intended to support a wheel of a vehicle or an aeroplane, and coupled to a movement-system making the upper-plate moving. The device is characterised in that it includes a mechanism by which the upper-plate(1,2,3,4) can be moved vertically thanks to the operation of a movement-system, whereby this mechanism comprises at least the following elements:     a ball-housing (6) with a ball; a threshold-block (7) with a bearing surface on which the ball rests (fig 8).   <IMAGE>
Patent DE-60105039-T2 (DE)
Inventor: GAULT ANTHONY JOHN
IPC: B21D39/02
Filed: 2001-09-28
Granted: 2005-08-18
Abstract: A method for forming a crimped joint between opposing overlapping portions (6,7) of the tubular body member (1) and end caps (2) to be secured thereto, which method comprises applying folding forces to the overlapping portions so as to form the crimped joint, characterised in that the folding forces are applied by a plurality of formers located circumferentially around the terminal portion of the tubular body member and urged without significant rolling action against the overlapping portions (6,7). The joint may be used to join end faces to silencer tubular members in vehicles exhausts.
Patent DE-60113277-T2 (DE)
Inventor: WHITNEY MORGAN
IPC: C07C67/10
Filed: 2001-06-15
Granted: 2006-06-14
Abstract: This invention relates to a method for preparing diaryl esters, comprising the step of reacting a mixture comprising diaryl carbonate and a dicarboxylic acid, wherein 2.005 to 2.2 molar equivalents of diaryl carbonate per molar equivalent of dicarboxylic acid are provided.
Patent DE-60117995-T2 (DE)
Inventor: SERRA DIDIER
IPC: G06K19/077
Filed: 2001-07-17
Granted: 2006-11-23
Abstract: An electronic tag (30, 40) is provided comprising a contactless integrated circuit (10) and a main coil antenna (Ls) comprising at least two distinct non-coplanar and/or non-coaxial windings (Ls1-Ls4) arranged in series. Applications to the reading of a tag from any face of a three-dimensional object.
Patent DE-60119173-T2 (DE)
Inventor: WELLER D
IPC: C12Q1/6832
Filed: 2001-08-30
Granted: 2007-01-18
Abstract: Disclosed are methods for separating, detecting, quantitating and/or isolating predominantly uncharged oligonucleotide analogs, by resolving duplexes of such molecules with complementary or near-complementary DNA or charged DNA analogs. The DNA or charged analog may be labeled for detection purposes.
Patent DE-60120211-T2 (DE)
Inventor: GOMI SHUN ICHI
IPC: A61K47/38
Filed: 2001-11-06
Granted: 2007-04-12
Abstract: Cellulose particles for pharmaceutical, which contains microcrystalline cellulose having an average degree of polymerization of from 60 to 350 in an amount of not less than 10%, and which have a tapped bulk density of from 0.60 to 0.95 g/ml, an aspect ratio of not less than 0.7, a shape factor of from 1.10 to 1.50, and an average particle size of from 10 to 400  mu m.