baber/WOPTO huggingface dataset:
Patent FI-923394-A (FI)
Inventor: PECCEU HENDRIK
IPC: F16H59/04
Filed: 1992-07-27
Abstract: A mechanical shifting device has a casing (1) and a ball (5) fitted therein in a cage (4). On the input side a shifting lever (2) is arranged radially downwards on the ball (5) and rigidly secured which, together with the ball (5), can make two rotary movements about axes (19, 24) passing mutually perpendicular through the centre (6) of the ball (5). On the output side there are two separate transmission components (13, 23) which take the form of pins and are arranged with their axes parallel to each other. The two transmission components (13, 23) are each connected to the ball (5) via a freewheel, whereby the two freewheels are so constructed and mutually arranged that one freewheel has a conveyor function for one transmission component (13) on the first rotary movement of the shift lever (2) and the other has a freewheeling function for the other transmission component (23), while the situation is reversed in the second rotary movement of the shifting lever (2).
Patent FI-925169-A (FI)
Inventor: CHANG GEORGE W
IPC: C12Q1/04
Filed: 1992-11-13
Abstract: A novel highly sensitive method for detection of the presence of total coliform and E. coli in water samples, food products, and seafood employs a new type of media having composition which allows an unequivocal detection of very small number of E. coli. The new low pH media which contain trimethylamine-N-oxide promote the growth of chlorine or food processing injured E. coli for their easier detection.
Patent FI-935314-A (FI)
Inventor: MOREIN BROR
IPC: A61K47/28
Filed: 1993-11-29
Abstract: The invention refers to the use of an inert, structure-giving, deadjuvanated matrix of a complex of a sterol, such as cholesterol, and one or more saponins as a carrier for the administration of a pharmaceutically active substance, and a drug carrying particle comprising said inert structure-giving matrix to which has been connected a pharmaceutically active substance. The drug carrying particle, delpha, has an annular basic structure which can form spherical nano particles having a size of 30-50 nm and a narrow size distribution.
Patent FI-940889-A (FI)
Inventor: WATJEN FRANK
IPC: C07D209/94
Filed: 1994-02-25
Abstract: A compound having the formula <CHEM>  wherein R<4> and R<5> independently are hydrogen, halogen, CF3, CN, NO2 or SO2NR<1>R<2> wherein R<1> is hydrogen or straight, C1-6-alkyl which may be branched or cyclic, R<2> is hydrogen or straight, C1-6-alkyl which may be branched or cyclic,  or wherein R<1> and R<2> together represent -(CH2)n-A-(CH2)m-, wherein A is O, S, CH2 or NR<I>, wherein R<I> is H, C1-6-alkyl which may be straight, branched or cyclic, n is 0, 1, 2, 3, 4, 5 and m is 0, 1, 2, 3, 4, 5;  Q is NOH, O;  Z = O, S, N-R<II>, <CHEM> wherein R<II>, R<III>, R<IV> and R<V> independently are hydrogen, benzyl, C1-6-acyl, C1-6-alkoxy which may be branched or cyclic, or C1-6-alkyl which may be branched or cyclic;  X is -(CH2)o- wherein o is 0, 1, 2, or 3;  Y is -(CH2)p- wherein p is 0, 1, 2 or 3;   alpha  and  beta  indicate attachment points, and a method of treating disorders of a mammal, including a human, responsive to the blockade of glutamic and aspartic acid receptors, with the same.
Patent FI-945706-A (FI)
Inventor: HEATH JR WILLIAM FRANCIS
IPC: A61K31/55
Filed: 1994-12-02
Abstract: This invention provides novel bis-indolemaleimide macrocycle derivatives of the formula: <CHEM> The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.
Patent FI-953223-A (FI)
Inventor: MACKOOL RICHARD J
IPC: A61B18/00
Filed: 1995-06-29
Abstract: A surgical instrument for removing a cataract from a patient's eye including a hollow vibrating needle surrounded by two hollow infusion sleeves. The outer sleeve conforms to the incision in the eye and the inner sleeve prevents the outer sleeve from collapsing onto the hollow, vibrating needle.
Patent FI-953812-A (FI)
Inventor: CRABTREE GERALD R
IPC: C12P21/06
Filed: 1995-08-11
Abstract: Dimerization and oligomerization of proteins are general biological control mechanisms that contribute to the activation of cell membrane receptors, transcription factors, vesicle fusion proteins, and other classes of intra- and extracellular proteins. We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins. In principle, any two target proteins can be induced to associate by treating the cells or organisms that harbor them with cell permeable, synthetic ligands. To illustrate the practice of this invention, we have induced: (1) the intracellular aggregation of the cytoplasmic tail of the ¶ chain of the T cell receptor (TCR)-CD3 complex thereby leading to signaling and transcription of a reporter gene, (2) the homodimerization of the cytoplasmic tail of the Fas receptor thereby leading to cell-specific apoptosis (programmed cell death) and (3) the heterodimerization of a DNA-binding domain (Gal4) and a transcription-activation domain (VP16) thereby leading to direct transcription of a reporter gene.  Regulated intracellular protein association with our cell permeable, synthetic ligands offers new capabilities in biological research and medicine, in particular, in gene therapy. Using gene transfer techniques to introduce our artificial receptors, one can turn on or off the signaling pathways that lead to the overexpression of therapeutic proteins by administering orally active "dimerizers" or "de-dimerizers", respectively. Since cells from different recipients can be configured to have the pathway overexpress different therapeutic proteins for use in a variety of disorders, the dimerizers have the potential to serve as "universal drugs". They can also be viewed as cell permeable, organic replacements for therapeutic antisense agents or for proteins that would otherwise require intravenous injection or intracellular expression (e.g., the LDL receptor or the CFTR protein).
Patent FI-991484-A (FI)
Inventor: SAASTAMOINEN ELJAS
IPC: B03B13/00
Filed: 1999-06-29
Abstract: An arrangement for measuring material flow, particularly concentrate flow, in connection with a flotation cell. The arrangement comprises an elongate sensor element extending essentially over the whole transversal area of the material flow to be measured, and a measuring device for detecting the position of the sensor element.
Patent GB-690543-A (GB)
Title: Lock nuts and their manufacture
Inventor: BOOTS NORMAN JAY
IPC: B21D53/24
Filed: 1952-01-14
Abstract: 690,543. Making nuts. BOOTS AIRCRAFT NUT CORPORATION. Jan. 14, 1952, No. 1052/52. Classes 83 (ii) and 83 (iv). [Also in Group XXV] Stamping.-Lock nuts are made from sheet metal strip 8, Fig. 3, by a series of drawing operations 9 to 15. At 16 the bottom of the cup is punched out and at 17 the end of the tubular body is bulged. The nut is then blanked out and the bulged end is slit to form teeth 4, Fig. 2, that are bent inwards prior to tapping, after which the teeth are bent further inwards to provide an interference fit with the bolt. In modifications the teeth are formed by milling &c. slots and the insetting is effected by a conical punch 30, Fig. 10.
Patent GB-146053-A (GB)
Title: An improved joint disconnectable for connecting earthenware sanitary appliances or the like to metal or other pipes or the like
IPC: E03D11/16
Filed: 1920-01-13
Abstract: 146,053. Baxter, A. E. Jan. 13, 1920. Spigot-and-socket joints held by cement &c.- The joint connecting an earthenware sanitary appliance a, Fig. 1, to a metal soil-pipe b is surrounded by a mould or casing, and the space between the latter and the pipes filled with a cementitious composition to effect a watertight joint. The casing consists of a lead collar c positioned around the soil-pipe at the floor-level, a wall f and a cover g fitted with studs on the underside, which become embedded in the jointing-composition. The collar c, wall f, and the cover g are each made in two parts, and are temporarily held together by wire until the composition is set. In a modification, Fig. 3, as adapted to connect a P trap to a metal pipe, the collar and cover are made integral with the casing wall c, which is joined in one or more parts, the cement being introduced through a hole in the wall of the mould. The jointing composition used consists of two parts of asphalt and one part bitumen, or some similar composition easily disconnected by the aid of a blow-lamp.
Patent GB-665919-A (GB)
Title: Improvements in wall panels
IPC: E04C2/292
Filed: 1949-01-14
Abstract: 665,919. Building units. ROBERTSON CO., H. H. Jan. 14,1949, No. 1120/49. Class 87(i) A building unit comprises corrugated and flat metal plates 12, 14 secured together in spaced relation by metal channel members 16 bolted thereto. The channel members may be of coated metal as described in Specification 391,936, [Group XIII]. A felt sheet 19 may be secured to the inner face of the corrugated metal plate 12 and the space between this and the flat plate 14 is filled by glass fibre boards 18. The side edges of the plates 12, 14 are bent to form tongues 20 and grooves 22. At the abutting horizontal edges of two units, the edges of the metal plates are offset at 24 for interengagement.
Patent GB-250661-A (GB)
Title: Improvements in or relating to the carbonization of coal, peat, wood and the like
IPC: C10B7/14
Filed: 1925-01-14
Abstract: 250,661. Winzer, C. B., and Brown, P. A. Jan. 14, 1925. Tunnel ovens; charging and discharging.-In the carbonization of coal, wood, peat, and the like, in a continuous manner, the material, charged into containers, is passed through a closed oven heated by hot gases being circulated around the side, top and bottom walls of the oven in a somewhat spiral manner, the volatiles being collected as they are given off and the carbonized residue removed to a cool part of the oven. The material is charged from hoppers F into carriers C which mav be in the form of basket-like cages or have solid walls open at the top and bottom, these carriers being mounted in a platform B supported by roller bearings B<3>, B<4> and rotated by pinions B<1> meshing with a rack B<2>, The carriers are provided with doors C<1> hinged at c and having wheels c<1> running on a track until the discharged position in reached when, as shown in Fig. 4, the doors drop automatically and the residue falls into a truck H removed through doors A<3>, A<4> forming a gas seal. On rotation of the platform B the carriers are passed through the chamber A and subjected to a gradually increasing temperature by the hot gases from the furnaces D, D<1> circulating in flues a<1> - - a<6> which heat the chamber A from all sides and escape by a flue E. In an alternative arrangement, a straight oven may be used, being raised by an elevator &c. to the level of the carriers C introduced through a door A<11> the heating chamber A and discharged when cool by similar means at the other end of the oven.
Patent GB-1012097-A (GB)
Title: Multiconductor plastic insulated telephone cables
Inventor: RAMBOL ARVE
IPC: H01B11/00
Filed: 1963-01-10
Abstract: 1,012,097. Electric cables. STANDARD TELEPHONES & CABLES Ltd. Jan. 10, 1963, No. 1218/63. Heading H1A. A multi-conductor telephone cable comprising a number of pairs each consisting of two conductors 1, 2 (Fig. 3) embedded in and separated by a web of plastics insulation is constructed in such a way that the total amount of insulation required for each conductor pair in the cable is less than that required for each conductor pair in a cable having conventional pairs (Fig. 1, not shown) and having the same mutual capacitance. The web of each pair is of such a length and thickness that the lower mutual capacitance it provides directly between the conductors of the pair as compared with that directly between the conductors of conventional pair having concentric insulation compensates for the increase in mutual capacitance due to neighbouring pairs and an earthing screen, if one is is provided, which increase arises from the decrease in thickness of the insulation surrounding the conductors. The pairs which are individually twisted may be bunched or stranded together and enclosed within a helical winding of plastics material 3 (Fig. 4) and an outer covering 4. Fins may be included in the shape of the insulation to space the pairs apart and the thickness of the web is chosen to be in accordance with mechanical and extrusion requirements.
Patent GB-691312-A (GB)
Title: Improvements in and relating to methods of and means for measurement
IPC: G01G23/00
Filed: 1950-01-17
Abstract: 691,312. Determining specific gravity. CARTON, J. Jan. 17, 1950 [Jan. 18, 1949], No. 1231/50. Class 97 (iii). [Also in Groups XVIII and XXXVIII] In apparatus for recording the variations in the specific gravity of a gas in an air-tight vessel 3 containing a sealed bulb 43, the gas is introduced into the space between the bulb 43 and the container 3 by inlet connections 32. The vessel 3 is carried at one end of a balance beam 1 supported on a knife edge 47, and carrying near its other end a vessel 44 whereby temperature and pressure variations are compensated. The vessel 44 carries an electrical contact 25 co-operating with a fixed contact 24 which is mounted on a fixed bracket 48 and is electrically connected with a switch 18, 19, 20, controlled by an electromagnet 22 and in circuit with an electric motor 15, 16. This motor is adapted to rotate a shaft 12 supporting a drum 1 at 9 and a string 27 supporting a weight 36 slidable on a rod 37. The weight 36 carries a stylus 28 whose free end rests on a rotatable drum 29. Balance beam 1 is adjustable by screws 38, 39 which are initially set so that at the balanced position corresponding to the initial specific gravity of the gas the contact 25 engages contact 24. When this occurs, motor 15, 16 is caused to rotate drum 11 so that the chain 6 is lowered, the equilibrium thereby destroyed and the contacts 24, 25 disengaged. Such disengagement results in de-energization of electromagnet 22 with the consequence that the drum 11 is rotated in the reverse sense and the chain 6 wound up until balance is restored and the contacts 24, 25 re-engaged. So long as the gas retains its initial specific gravity these operations are repeated automatically and stylus 28 traces out a sine curve. When the specific gravity is varied, the stylus will trace out curve corresponding to the variations.
Patent GB-1452998-A (GB)
Title: Device for handling granular material
IPC: G01F11/00
Filed: 1974-01-10
Abstract: 1452998 Discharging hoppers K M ALLEN 10 Jan 1974 [21 May 1973] 01282/74 Heading B8S A device for controlling the discharge of granular material, e.g. salt, from a plurality of openings 24 in the bottom 22 of a hopper 10, comprises a plate 52 supported directly below the hopper bottom 22 to prevent continuous flow through the openings, and having orifices 50 therein normally staggered in relation to the openings 24, the plate 52 being reciprocable to facilitate pushing of the material into the orifices 50. The openings 24 in the hopper bottom are tapped to adjustably threadedly receive nipples 30 having orifices 26 therethrough, spreader plates 32 being mounted at the lower ends of the nipples to effectively push the material due to movement of the plate 52. A sharp threaded rod 34 is carried by leaf springs 36 secured at their upper ends to the hopper, the lower ends of the spring mount the plate 52 therebetween, and reciprocation of the plate 52 and rod 34 is effected by driven eccentric cams 64, 66 engaging one of the spring 36. The rod 34 acts as a file to break lumps of the material in the hopper.
Patent GB-101433-A (GB)
Title: The Manufacture and Production of New Indophenolic Compounds and of Dyestuffs therefrom.
IPC: C09B49/10
Filed: 1916-01-27
Abstract: 101,433. Claus & Co., and Wray, E. Jan. 27, 1916. Carbazyl-N-acetic acid and esters thereof are obtained by condensing carbazole, or an alkalicarbazole, with chlor-acetic acid or an ester thereof. Indophenols are obtained by condensing car. bazyl-N-acetic acid, or an ester thereof, with p-nitrosophenol, or a homologue or derivative thereof, in concentrated sulphuric acid solution; leuco-indophenols are obtained by reduction. Sulphuretted dyes are obtained by heating the above-described indophenols or leuco-indophenols with a sulphurizing-agent, such as an alkali polysulphide, or sulphur; solvents and metallic salts, such as copper sulphate, may be present. The products dye cotton blue shades from a hvdrosulphide vat or an alkali sulphide bath. Specification 9689/09 is referred to.
Patent GB-1404303-A (GB)
Title: Solenoid valves
IPC: F16K31/06
Filed: 1974-01-11
Abstract: 1404303 Electromagnets CHRISTIAN BURKERT BAU ELEKTRISCHER GERATE GmbH 11 Jan 1974 [25 May 1973] 1365/74 Addition to 1390334 Heading H1P [Also in Division F2] The invention of the parent Specification 1,390,334 is modified by the provision of longitudinal channels in the bore of the plastics bobbin, the channels being preferably arranged symmetrically. The armature is preferably of stainless steel and is round in cross-section.
Patent GB-345000-A (GB)
Title: Improvements in and connected with gaseous fuel fires and stoves
IPC: F24C3/04
Filed: 1930-01-15
Abstract: 345,000. Gas fires. MUSKER, A., 301, Abbey House, Westminster. Jan. 15, 1930, No. 1401. [Class 126.] The heat radiated backwardly from the radiants 3 of an incandescent gas fire is utilized to heat air, which passes upwardly between closely-disposed series of metal plates, tubes, or other parts 12 arranged behind the radiants, the plates &c. being heated by radiationfrom one to another. In the stove shown, a number of thin metal plates 12, with a forwardly - convex curvature in plan, are arranged parallel and close to one another in a casing formed by a front plate 13, the back 1 of the stove, and sideplates. The air, after heating, is delivered where required by way of an outlet 6. The plates 12 may be corrugated. The air to be heated may be supplied by natural, forced, or induced draught.
Patent GB-112524-A (GB)
Title: Improvements in Holders for Fountain Pens, Pocket Combs, and other Articles for use in Waist-coat Pockets and the like.
Inventor: SANGSTER CHARLES THOMAS BROCK
IPC: A45F5/02
Filed: 1917-01-29
Abstract: 112,524. Sangster, C. T. B., and Foley, J. S. Jan. 29. 1917. Pockets, retaining pens, pencils, combs, eye. glasses, &c. in.-A device for holding articles within a pocket, and of the kind comprising one or more rows of flexible depending tongues a, is formed with an elongated socket b. The socket may be formed of sheets folded from the metal composing the tongues, the sheets being united at their ends by U-shaped pieces b<1>. The front of the socket may be bulged as shown in Fig. 5. to accommodate bulky articles, the tongues being correspondingly shaped.
Patent GB-112973-A (GB)
Title: Manufacture of a New Compound of Zirconium and its application in the Production of Pure Zirconia.
IPC: C01G25/06
Filed: 1917-01-29
Abstract: 112,973. Imperial Trust for the Encouragement of Scientific & Industrial Research, Glazebrook, R. T., Rosenhain, W., and Rodd, E. H. J'an. 29, 1917. Zirconium oxide, oxychloride, and basic sulphate.-Basic zirconium sulphate is obtained by the addition of an alkali such as ammonia or caustic soda to an acid solution containing zirconium sulphate, and preferably hydrochloric acid until a permanent precipitate begins to form, and then allowing precipitation to continue by itself. The sulphate solution may be made by heating together crude zirconia, tiuorspar, and sulphuric acid, adding water, separating thecalcium sulphate, and adding some hydrochloric acid. The basic sulphate can be converted into oxide by ignition or into hydroxide by suspending in water and agitating with ammonia. The basic sulphate may be made in purer condition by dissolving zirconium hydroxide in hydrochloric acid, concentrating, and crystallizing, a mixture of a new basic oxychloride Zr5O8Cl422H2O with the known oxychloride ZrO2Cl28H2O being obtained. The new oxychloride is separated by recrystallization from hydrochloric acid, and is dissolved in water and treated with sulphuric acid or a solution of a sulphate equivalent to the contained chlorine, the rew basic sulphate 5ZrO22SO314H2O being precipitated. The hydrochloric acid mother-liquor contains zirconium which may be precipitated as a basic sulphate free from iron by addition of sulphuric acid.
Patent GB-1307341-A (GB)
Title: 5-azaspiro-2,4-heptane-4,6-diones
IPC: C07D207/448
Filed: 1971-01-12
Abstract: 1307341 Azaspiroheptanediones A H ROBINS CO Inc 12 Jan 1971 [26 Jan 1970] 1497/71 Heading C2C Novel compounds I: in which R is H, 1-8C alkyl, 1-80 hydroxyalkyl, phenyl,phenyl-1-8C alkyl, (1-8C alkyloxy)-phenyl, (1-80 alkyl)phenyl, trifluoromethyl-phenyl or halophenyl; R 1  is phenyl optionally substituted by 1-8C alkyl or alkoxy, CF 3  or halo; and R 2  is H or R 1  are prepared as indicated in chart A: In the chart R 3  is 1-80 alkyl, M is a metal, Z is H or NH 2  and X is halogen. Compounds IV, V, VI, VII, IX and X in the chart may be isolated as intermediates.
Patent GB-622305-A (GB)
Title: Drying of penicillin
IPC: C07D499/18
Filed: 1947-01-16
Abstract: Substantially anhydrous penicillin salts are isolated from aqueous solutions thereof by mixing with an inert entrainer which is substantially immiscible with water and is a non-solvent for the penicillin salt, heating the mixture to a temperature below that at which the aqueous penicillin salt is decomposed (e.g. about 15-40 DEG C.) to distil a mixture of water and the inert entrainer, continuing distillation until substantially all the water has been removed, and recovering the anhydrous penicillin salt from the residual inert entrainer, e.g. by filtration.  The distillation is preferably effected under reduced pressure, e.g. about 15-100 mm. of mercury. Suitable inert entrainers are benzene, petroleum ether, chloroform, ethylene dichloride and chlorobenzene, or mixtures thereof.  Examples describe the production of sodium and calcium penicillin.
Patent GB-157856-A (GB)
Title: Manufacture of tanning stuffs and process of tanning therewith
IPC: C14C3/08
Filed: 1921-01-10
Abstract: Synthetic tanning-agents are prepared from tars or tar oils by converting the components thereof into phenols by sulphonation and alkali fusion, coupling the resulting phenols by appropriate elements or radicals, and solubilizing the products by introducing acid groups; alternatively the acid groups are introduced into the phenols and the metal salts of the products then coupled.  According to examples:-a tar oil is sulphonated and converted through the calcium salt into the sodium salt which is then subjected to alkali fusion; the resulting phenol is heated with phosphorus pentoxide and sulphuric acid and the product neutralized or nearly neutralized with alkali; or the phenol is sulphonated by concentrated sulphuric acid and condensed with sulphur monochloride and the product nearly neutralized with caustic soda; or the phenol is sulphonated and condensed with formaldehyde and neutralized as described above, or alternatively the phenol is sulphonated, the product made feebly alkaline and condensed with formaldehyde, the resulting solution being made feebly acid before use.  The sulphuric acid may be replaced by sodium sulphite or bisulphite &c.  The products may be used in tanning, alone or mixed with other tanning-agents.  Hides tanned with these materials may be dyed by treatment with diazo compounds.  Specification 157,852 is referred to.ALSO:Hides tanned with certain synthetic tanning agents may be dyed by treatment with diazo-compounds.  These tanning-agents are prepared from tars or tar oils by converting the components thereof into phenols by sulphonation and alkali fusion, coupling the resulting phenols by appropriate elements or radicals, and solubilizing the products by introducing acid groups; alternatively the acid groups are introduced into the phenols and the metal salts of the products then coupled. Specification 157,852 is referred to.