baber/WOPTO huggingface dataset:
Patent DK-0841339-T3 (DK)
Inventor: ANGEHRN PETER
IPC: C07D501/06
Filed: 1997-10-29
Granted: 2007-07-02
Abstract: The present invention relates to cephalosporin derivatives of the general formula <CHEM>  where   R<1>   is halogen, lower alkyl, phenyl, benzyl, styryl, naphthyl or heterocyclyl; the lower alkyl, phenyl, benzyl, styryl, naphthyl and heterocyclyl being optionally substituted by at least one of halogen, hydroxy, optionally substituted lower alkyl, optionally substituted lower alkoxy, optionally substituted phenyl, amino, lower alkylamino, di-lower alkylamino, carboxy, lower alkylcarboxy, carbamoyl or lower alkylcarbamoyl; R<4>, R<5>   independently are hydrogen, lower alkyl or phenyl; X   is S, O, NH or CH2; n   is 0,1 or 2; m   is 0 or 1; s   is 0 or 1; R<2>   is hydrogen, hydroxy, -CH2-CONHR<6>, lower alkyl-Qr, cycloalkyl-Qr, lower alkoxy, lower alkenyl, cycloalkenyl-Qr, lower alkynyl, aralkyl-Qr, aryl-Qr, aryloxy, aralkoxy, a heterocyclic ring or a heterocyclyl-Qr, the lower alkyl, cycloalkyl, lower alkoxy, lower alkenyl, cycloalkenyl, lower alkynyl, aralkyl, aryl, aryloxy, aralkoxy and the heterocyclic ring may be substituted with at least one group selected from carboxy, amino, nitro, cyano, -SO2NHR<6>, optionally fluoro substituted lower alkyl, lower alkoxy, hydroxy, halogen, -CONR<6>R<7>, -CH2CONR<6>R<7>, -N(R<7>)COOR<8>, R<7>CO-, R<7>OCO-, R<7>COO-, -C(R<7>R<9>)CO2R<8>, -C(R<7>R<9>)CONR<7>R<10>, wherein     R<6> is hydrogen, lower alkyl, cycloalkyl or aryl;   R<7> and R<9> are independently hydrogen or lower alkyl; R<8> is hydrogen, lower alkyl, lower alkenyl or a carboxylic acid protecting group; and R<10> is hydrogen,  omega -hydroxy-alkyl, phenyl, naphthyl or heterocyclyl, the phenyl, naphthyl or heterocyclyl being unsubstituted or substituted with at least one of the groups of optionally protected hydroxy, halogen, optionally substituted lower alkyl or  omega -hydroxyalkyl, optionally substituted lower alkoxy and/or cyano, or R<7> and R<10> form together group of formula <CHEM>     Q   is -CHR-, -CO- or -SO2-; r   is 0 or 1; R   is hydrogen or lower alkyl; and R<3>   is hydroxy, -O<->, lower-alkoxy, or -OM and M represents an alkali metal; as well as readily hydrolyzable esters thereof, pharmaceutically acceptable salts of said compounds and hydrates of the compounds of formula I and of their esters and salts, as wen as the preparation of such compounds, their use for the treatment of infectious diseases and pharmaceutical preparations containing such compounds.
Patent DK-0941066-T3 (DK)
Inventor: BISCHOFF RAINER
IPC: A61K48/00
Filed: 1997-08-25
Granted: 2004-02-23
Abstract: The invention is related to a method for preparing an homogenous suspension of stable lipid-nucleic acid complexes or particles, comprising: a) combining one or more cationic lipids, one or more colipids, and one or more stabilizing additives to form a lipid suspension, b) combining the lipid suspension with a nucleic acid to form a complex or a particle, and optionally c) subjecting the complex or particle to a sizing procedure. It also concerns an homogenous suspension produced notably by the above method.
Patent DK-1004656-T3 (DK)
Inventor: CASTEEL SASCHA
IPC: C11D17/00
Filed: 1998-11-11
Granted: 2001-02-05
Abstract: Compressed granulate contains highly pure cellulose and/or cellulose derivative that is insoluble but swells in water, finely-divided (co)polymer of (meth)acrylic acid or salt and liquid surfactant(s) that thickens or forms a gel with water. An Independent claim is also included for the production of the compressed granulate.
Patent DK-0931838-T3 (DK)
Inventor: GISELBRECHT KARL-HEINZ
IPC: C12P13/20
Filed: 1998-12-22
Granted: 2002-04-02
Abstract: An improved process for preparing L-aspartic acid by enzyme-catalyzed reaction of fumaric acid with ammonia, in which, after reaction has been completed, excess ammonia is removed from the reaction mixture, L-aspartic acid is precipitated by adding acetic acid or formic acid, whereupon formic acid and acetic acid are rereleased from the mother liquor by adding fumaric acid, and the ammonia released and the liberated formic or acetic acid and the ammonium fumarate formed in the liberation are reused for subsequent cycles.
Patent DK-0921857-T3 (DK)
Inventor: PHAM ANDREW A
IPC: G01N21/64
Filed: 1998-05-29
Granted: 2007-11-05
Abstract: The invention provides for multi-well plates and platforms that comprise a layer of having low fluorescence and high transmittance. These multi-well plates and platforms are particularly well suited for fluorescent measurements.
Patent DK-0997393-T3 (DK)
Inventor: MARBLER CLAUDE
IPC: B65D77/28
Filed: 1999-07-02
Granted: 2003-06-02
Abstract: The bag(10) has a first section(32) to hold a liquid substance and a second section(34) separated fluidtight from the first section to accommodate a drinking straw section(42). The straw(38,42) leads from the first section into the second section, is connected fluidtight to the bag in the transition region, and has a valve element for opening and closing of the flow passage(37). The straw may have a joint movable between an open and closed position by hinging or twisting the straw section protruding into the second section.
Patent DK-1058687-T3 (DK)
Inventor: WAEHLING HORST
IPC: C07D473/00
Filed: 1999-02-12
Granted: 2004-03-15
Abstract: Compounds of formula (I) wherein R is independently H or -CH3 and pharmaceutically acceptable salts thereof have favourable pharmacological properties and are antivirally active against HBV and HIV.
Patent DK-0977610-T3 (DK)
Inventor: DAIGNAULT KENNETH J JR
IPC: A61M25/01
Filed: 1999-02-23
Granted: 2005-11-28
Abstract: A self-contained, self-lubricating catheter assembly is provided. A receptacle formed of two opposed flexible walls includes a main chamber and a lubrication chamber separated by a passage. A lubricant is provided in the lubrication chamber. A catheter is advanced from the main chamber through the lubrication chamber and picks up lubricant as it is passes through the lubrication chamber. A catheter grasping mechanism, located proximate the exit from the lubrication chamber, permits advancement of the catheter out of the receptacle and resists movement of the catheter back into the receptacle. The receptacle also includes one or more finger holes therethrough to allow the user to retain the receptacle on one or more fingers, thereby allowing the hand to more readily position the receptacle during use while advancing the catheter.
Patent DK-1085907-T3 (DK)
Inventor: RE ROBERT G
IPC: A61K9/08
Filed: 1999-06-08
Granted: 2004-06-21
Abstract: This invention comprises new formulations and methods of preparing a new formulations of prostaglandins and in particular dinoprost tromethamine, where the pH of the formulation is adjusted to between about 5.5-7.5 and where the the concentration of benzyl alcohol is between about 1.2 to 2.0 mg/ml.
Patent DK-1102703-T3 (DK)
Inventor: KUENG EDUARD RENE
IPC: B65D1/02
Filed: 1999-07-31
Granted: 2003-01-27
Abstract: A plastic container for liquid and solid matter such as pesticides, made from a semi-rigid to rigid thermoplastic synthetic material, consisting of a top part with a closure (5) and, optionally, a handle (6), a bottom part (15) and a connecting middle part comprising two narrow sides and two wide sides. The narrow sides have bent lips (3) and the wide sides have folded grooves (1). The invention is characterised in that folded lips are disposed horizontally at approximately half the way up the narrow sides of the container and a peripheral folded groove that is optionally interrupted in the centre is provided on the same level as the narrow and wide sides, whereby the folded groove runs through the largest recess of the bent lips. When empty, the container can be folded together, without the risk of breakage, in order to reduce volume.
Patent ES-2247973-T3 (ES)
Title: Polvos de caucho que contienen grandes cantidades de cargas, procedimiento para su preparacion y su uso.
Inventor: GORL UDO DR
IPC: C08L101/00
Filed: 2000-05-09
Granted: 2006-03-16
Abstract: Procedimiento para la preparación de polvo de caucho que contiene una o varias carga(s) oxídica(s) o silicática(s), especialmente un ácido silícico precipitado, en una cantidad > 250 pcc hasta 5000 pcc, cuando se trata de una carga sintética de este tipo, o en una cantidad > 350 pcc hasta 5000 pcc, cuando se trata de una carga natural, cuya superficie se modifica durante la preparación con uno o varios compuestos de organosilicio de las fórmulas generales [R1n(RO)3-n Si-(Alc)m-(Ar)p]q [B] (I), R1n(RO)3-n Si-(alquilo) (II), o R1n(RO)3-n Si-(alquenilo) (III), en las que B: -SCN, -SH, -Cl, NH2 (si q = 1) o R y R1: un grupo alquilo con 1 a 4 átomos de carbono, ramificado o no ramificado, el resto fenilo, en que todos los restos R y R1 pueden tener respectivamente el mismo significado o uno diferente, con preferencia un grupo alquilo, n: 0; 1 ó 2, Alc: un resto hidrocarburo divalente lineal o ramificado con 1 a 6 átomos de carbono, m: 0 ó 1 Ar: un resto arileno con 6 a 12 átomos de C p: 0 ó 1, con la condición de que p, m y n no signifiquen 0 simultáneamente, x: un número de 2 a 8, Alquilo: un resto hidrocarburo saturado monovalente lineal o ramificado con 1 a 20 átomos de carbono, con preferencia 2 a 8 átomos de carbono, Alquenilo: un resto hidrocarburo insaturado monovalente lineal o ramificado con 2 a 20 átomos de carbono, con preferencia 2 a 8 átomos de carbono, solos o en combinación con negro de carbono en una cantidad > 250 pcc hasta 5000 pcc, en que la cantidad total de carga no sobrepasa 5000 pcc.
Patent ES-2270772-T3 (ES)
Inventor: CHEN PING
IPC: C07K19/00
Filed: 2000-10-31
Granted: 2007-04-16
Abstract: The present invention relates to the identification, isolation and purification of the catalytic domain of the human effector checkpoint protein kinase (hChk1). A 1.7 &cir&  crystal structure of the hChk1 kinase domain in the active conformation is reported herein. The kinase domain of hChk1 and its associated crystal structure is described for use in the discovery, identification and characterization of inhibitors of hChk1. This structure provides a three-dimensional description of the binding site of the hChk1 for structure-based design of small molecule inhibitors thereof as therapeutic agents. Inhibitors of hChk1 find utility in the treatment of hyperproliferative disorders such as HIV and cancer.
Patent ES-2310985-T3 (ES)
Title: Procedimiento para la deposicion electrolitica a partir de una solucion que contiene cromo.
Inventor: HORSTHEMKE HELMUT
IPC: C25D3/10
Filed: 2000-11-11
Granted: 2009-02-01
Abstract: Procedimiento para el revestimiento de materiales, especialmente de materiales metálicos, en el que, para la formación de una capa resistente a la corrosión y especialmente a cloruros que destaca por un alto brillo, se deposita una aleación de cromo a partir de un electrolito que además de ácido crómico y ácido sulfúrico contiene al menos un metal que forma isopolianiones del grupo constituido por molibdeno, vanadio, wolframio y niobio así como un compuesto orgánico, caracterizado porque se añade al electrolito como aditivo un compuesto de selenio y/o teluro en un intervalo desde 0,25 mmol/l hasta 2,5 mol/l.
Patent ES-2230023-T3 (ES)
Inventor: SCHLENKERT GERT
IPC: F41A21/22
Filed: 2000-12-07
Granted: 2005-05-01
Abstract: The method involves depositing the chrome layer electrolytically with a pulsed electric current. A number of sub-layers of chrome is deposited corresponding to the number of electric current pulses and the pulse length is selected so that the crystal growth during the individually deposited sub-layers is interrupted before it ends naturally and the chrome layer has a globular polytropic structure.
Patent ES-2312324-T3 (ES)
Inventor: HIEBEL CLAUDE
IPC: H04W88/02
Filed: 2000-01-20
Granted: 2009-03-01
Abstract: The flap movement is used to determine the operational state of the phone.  The portable radio telephone comprises a box (1) and a mobile flap (12) rotating about the corner of the box. The flap may adopt one of three positions, a folded position, an open position or an intermediate position. A detector (16) senses the position of the flap and a switch is associated with the detector. The switch acts to put the phone off-hook when the flap is open, on-hook when the flap is closed, and in hands-free mode when the flap is in the intermediate position. The hinge for the flap includes a spring and detent mechanism, defining the three rest positions of the flap.
Patent ES-2240039-T3 (ES)
Title: Dispositivo para suministrar porciones envasadas de cafe molido a una unidad de escaldado.
Inventor: SCHMED ARTHUR
IPC: A47J31/02
Filed: 2000-03-29
Granted: 2005-10-16
Abstract: Dispositivo (1) para alimentar porciones envasadas de café molido a una unidad de escaldado (2), con un almacén (3) para alojar las porciones de café que se vayan a preparar (21, 22, 23) caracterizado porque el almacén (3) está dispuesto giratorio y puede contener varios cartuchos (4) para el alojamiento de porciones de café (21, 22, 23), y por estar previstos medios (7, 14, 25, 26, 27) para entregar individualmente las porciones de café (21, 22, 23) a la unidad de escaldado (2).
Patent ES-2248036-T3 (ES)
Inventor: MAGNI RICCARDO
IPC: B66F9/065
Filed: 2000-03-28
Granted: 2006-03-16
Abstract: The high lift truck for raising loads to considerable heights comprises a vehicle having a chassis (2) which is mobile on wheels or tracks. A load-bearing arm (7) has a lower end constrained to a slide (4) which is slidable on the chassis (2) in a horizontal direction. A counterweight (11) is constrained to the chassis (2) and can translate on command in a parallel direction to the sliding direction of the slide (4), in both senses, between two extreme endrun positions. The translations of the counterweight (11) and the slide (4) are correlated so that when the counterweight (11) slides in one direction, the slide (4) moves in the opposite direction. The counterweight (11) is predisposed to balance the tilting moment exerted on the chassis (2) by a load (9) borne by the arm (7) and raised to a considerable height. <IMAGE>
Patent ES-2234557-T3 (ES)
Inventor: MARAGGI GIUSEPPE
IPC: B60J7/06
Filed: 2000-05-24
Granted: 2005-07-01
Abstract: This invention concerns a folding cover for trucks with side walls that can open for unloading to the side. The cover is commanded by a mechanism with a rotating shaft, two front pulleys, two rear pulleys and two ropes drawn over the aligned pulleys along the sides of the truck body. Each front pulley can be coupled and uncoupled (20, 23) with a corresponding end of said shaft and the ends of the ribs (12, 12') of the cover are fastened in a detachable way to each tow rope (19) and can be removed when the side walls are opened. <IMAGE>
Patent ES-2222888-T3 (ES)
Inventor: ROTA PAOLO
IPC: A45F3/04
Filed: 2000-08-11
Granted: 2005-02-16
Abstract: Associated to the backrest (2) of a rucksack (1) is an elastic strip (6) set in the vertical direction of the backrest (2), the strip (6) lying in a plane parallel to the backrest (2) and having its ends operatively connected to the backrest (2) in such a way that a deformation due to bending of the backrest (2) according to the dorsal arch of the user generates an elastic reaction of the strip (6) tending to cause the backrest (2) to return into the undeformed condition so as to favour correct resting of the rucksack on the spine of the user.
Patent ES-2223500-T3 (ES)
Inventor: KITTSON MARK
IPC: E02D29/02
Filed: 2000-04-03
Granted: 2005-03-01
Abstract: A geotextile fabric constructed as a bi-axially oriented, open grid of high modulus of elasticity strands impregnated with resinous material which is flexible when cured. The fabric may be stored and installed in roll or sheet form and provides high-strength, low-strain reinforcement of earthen structures which is resistant to abrasion, water and chemical attack from soil.
Patent ES-2304965-T3 (ES)
Inventor: HAAHEIM LARS REINHARDT
IPC: G01N33/68
Filed: 2000-06-14
Granted: 2008-11-01
Abstract: The present invention provides a method of determining the presence or amount of newly synthesised antibody in a sample in response to an immunogen by detecting the released antibodies or parts thereof in a sample containing lymphocytes which have been disrupted whereby to release the synthesised antibodies or parts thereof associated with said lymphocytes whereby to determine the presence or amount of newly synthesised antibody in said sample, methods of diagnosis using said method and kits for performing the method. The method may also be modified to allow detection of non-specific infection indicators.
Patent ES-2254211-T3 (ES)
Inventor: METELLI LUIGI
IPC: E04B1/21
Filed: 2000-08-02
Granted: 2006-06-16
Abstract: The invention concerns a girder in reinforced concrete that has a flat intrados (11) and a flat or sloping extrados (12), which consists of two symmetrical halves or girders (13, 14) with adjacent parts that meet in a plane mid-way (15), perpendicular to the intrados, and equipped, near the extrados (12), with connecting plates for bolting (16) and, near the intrados (11), with a joint device (17) that has bars which are parallel to the intrados.
Patent ES-2296656-T3 (ES)
Inventor: PURDY DESMOND
IPC: A61K48/00
Filed: 2000-11-13
Granted: 2008-05-01
Abstract: Agents are provided which are capable of inhibiting the cell division cycle in a target cell of interest. The agents comprise first and second components, wherein the first component is a targeting moiety which is capable of directing the second component to the target cell of interest. The second component is capable of inhibiting the cell division cycle in the target cell of interest. The agents are preferably provided in the form of conjugates, and the second component is preferably a cytolethal distending toxin. Methods for the preparation of the agents, and the use thereof for treating proliferative cell disorders and intracellular pathogens are also provided.
Patent ES-2354866-T3 (ES)
Inventor: DAY ANTHONY
IPC: C12N15/09
Filed: 2000-12-14
Granted: 2011-03-18
Abstract: An improved cellulase comprising an amino acid sequence which has been modified from a precursor amino acid sequence by the substitution or deletion of an amino acid residue which differs from a corresponding amino acid residue in a less stable but homologous cellulase, wherein said improved cellulase has improved thermostability compared to a cellulase corresponding to the precursor amino acid sequence.
Patent ES-2287046-T3 (ES)
Title: Polimeros de hidroxi-fenoxieter en la fabricacion de papel.
Inventor: LEE ROBERT A
IPC: C08J11/00
Filed: 2000-12-20
Granted: 2007-12-16
Abstract: Procedimiento para realizar una lámina de papel u objeto tridimensional, que comprende: proporcionar un lodo de pasta o banda de papel, proporcionar una solución o dispersión que comprende un polímero de hidroxi-fenoxiéter, entremezclar dicha solución o dispersión con dicho lodo de pasta o banda de papel para formar un aditivo, y conformar una lámina de papel u objeto tridimensional de dicho aditivo, en el que el pH de la solución, dispersión o aditivo se ajusta para precipitar por lo menos una parte de dicho polímero de hidroxi-fenoxiéter y dicho polímero de hidroxi-fenoxiéter se utiliza en una cantidad que sea efectiva para dotar a dicha lámina de papel u objeto tridimensional de un aumento en el apresto o la resistencia.
Patent ES-2263530-T3 (ES)
Inventor: KELLER HARALD
IPC: C09D7/65
Filed: 2001-05-07
Granted: 2006-12-16
Abstract: A composition for the production of poorly wettable surfaces contains   (i) finely-divided powder comprising particles with a hydrophobic surface and a porous structure characterized by a BET surface (DIN 66131) of at least 1 m<2>/g; and (ii) film-forming binder(s) with a surface tension of less than 50 mN/m, in a powder:binder wt. ratio of at least 1:4. Independent claims are also included for (a) a method for the production of poorly wettable surfaces by coating a conventional surface with the composition described; and (b) molded products with surfaces substantially consisting of such a composition.
Patent ES-2233528-T3 (ES)
Inventor: REATTI RODOLFO
IPC: B65G47/68
Filed: 2001-07-12
Granted: 2005-06-16
Abstract: Am element (S) for walls (A, B) supporting a plurality of idle rollers, particularly for accumulation stations for conveying lines for products in general, comprises two components (1, 1; 1, 2) coupled together, said components being identical (1, 1) in the case of central walls, and different (1, 2) in the case of side walls, one of said different components (1, 2) being identical, i.e. "common", to those relative to the central walls (1). <IMAGE>
Patent ES-2227074-T3 (ES)
Inventor: SATO TEIZO
IPC: B26B19/14
Filed: 2001-07-05
Granted: 2005-04-01
Abstract: A shaver comprising an outer blade (1) with an annular array of radially disposed slots (2) which taper inwards towards the blade's centre. An inner blade (3), with substantially radially disposed sub-blades rotates concentrically with the outer blade (1). A portion of each sub-blade sweeps around an inner surface of the outer blade (1) adjacent the slots (2) and has, at a radially outermost portion, a gap (8) between the inner and outer blades (1, 3) for assisting in the cutting of hairs extending through the slots (2). Each gap (8) tapers inwardly towards the centre of the inner blade (3) and may be at least partially filled with a material ( alpha ) which may be resilient and/or adhesive. A resilient assisting means, which may support the material ( alpha ), may be provided close to and rotate with the inner blade (3) for assisting in the trapping of hairs. The inner and outer blades may alternatively be of a linear form and reciprocate longitudinally relative to each other. <IMAGE>
Patent ES-2245970-T3 (ES)
Inventor: DANE BERNARD
IPC: F24C3/08
Filed: 2001-01-09
Granted: 2006-02-01
Abstract: A gas burner with multiple gas rings comprising: a burner body (6) mountable underneath a top plate, with a cut-out section, of an appliance and incorporating a first, upwardly directed gas injector (14) and a second gas injector (9) followed by a horizontal tubular Venturi (10) opening into a vertical well (12); an outer burner head (3) seated on the body (6) through the cut-out section and spaced at a distance above the plate and provided with an annular chamber (22) open above the well (12) and having one or two rows of orifices for flames (4,5); and an inner burner head (1) shaped so as to have a radial divergent (37) coaxially supplied by the first injector through a recess located at the center (31) of the head (3), ports being provided in the head (3) so that all the primary air and the secondary air needed to operate the multiple burner arrives from the top of the top plate of the appliance.
Patent ES-2223744-T3 (ES)
Title: Dispositivo destinado a equipar una parte interior de la caja de un vehiculo automovil.
Inventor: POURRIAS JEAN-YVES
IPC: B60R13/04
Filed: 2001-01-12
Granted: 2005-03-01
Abstract: Dispositivo destinado a equipar una parte inferior de la caja de un vehículo automóvil que comprende una primera parte (4) añadida de modo fijo a la citada parte inferior de caja (1, 2) y una segunda parte escamoteable móvil entre dos posiciones; caracterizado porque estas dos posiciones son: - una posición abatida en la cual la compatibilidad de la parte inferior de la caja con un sistema de elevación del vehículo es limitada y - una posición escamoteada separada en la cual el sistema de elevación del vehículo puede apoyarse en la parte inferior de la caja.
Patent ES-2232588-T3 (ES)
Inventor: FOGUET RAFAEL
IPC: C07C235/80
Filed: 2001-01-04
Granted: 2005-06-01
Abstract: The present invention relates to a process for preparing (±)-trans-4-p-fluorophenyl-3-hyroxymethyl-1-methylpiperdine of formula (I). The present invention also relates to novel intermediates of the formula (IX) and (IX') methods for preparing said intermediates and the use of said compounds for preparing Paroxetine and Omiloxetine.