baber/WOPTO huggingface dataset:
Patent DK-0934069-T3 (DK)
Inventor: CINCOTTA ANTHONY H
IPC: A61K31/58
Filed: 1997-05-06
Granted: 2007-03-19
Abstract: This invention is directed to modifying or regulating in a subject of at least one of lipid and glucose metabolism by administering to a subject in need of such treatment a dopamine D1 agonist in conjunction with one agent or agent combination selected from i) a dopamine D2 agonist, ii) at least one of an adrenergic alpha1 antagonist, an adrenergic alpha2 agonist and a serotonergic inhibitor, or iii) a dopamine D2 agonist further conjoined with at least one of an adrenergic alpha1 antagonist, an adrenergic alpha2 agonist and a serotonergic inhibitor.
Patent DK-0948510-T3 (DK)
Inventor: KLINMAN DENNIS
IPC: C12N15/117
Filed: 1997-10-30
Granted: 2006-10-30
Abstract: An isolated immunostimulatory oligonucleotide comprising two or more unmethylated CpG dinucleotides, and having a sequence including the following formula:  
5'N 1 X 1 X 2 CGTTN 2 3'  
wherein the immunostimulatory oligonucleotide includes a modified backbone, at least one nucleotide separates consecutive CpGs, X 1 X 2  is GpT or ApT, N 1  is any nucleotide that includes a 5' TC or TG, N 1  + N 2  is from 0-26 bases, and the immunostimulatory oligonucleotide is from 8-30 bases in length and begins with TC or TG at the 5' end, with the proviso that neither N 1  nor N 2  contains a CCGG quadmer or more than one CCG or CGG trimer.
Patent DK-0960132-T3 (DK)
Inventor: ALAMI YOUNES
IPC: A23L29/269
Filed: 1998-02-12
Granted: 2002-09-16
Abstract: The invention concerns a polysaccharide with a repeat unit having a lateral chain and comprising six neutral sugars among which glucose and galactose and an acid sugar, a solution greater than 0.2% by weight of said polysaccharide forming a transparent and elastic gel. The invention is applicable in the cosmetic, food, pharmaceutical and oil industries.
Patent DK-0979241-T3 (DK)
Inventor: BAJUSZ SANDOR
IPC: C07K14/81
Filed: 1998-04-22
Granted: 2006-06-26
Abstract: The invention relates to a new (3R)-3-amino-4-carboxybutyraldehyde derivatives of general formula(I)wherein X represents a C1-4 alkyloxycarbonyl, an optionally substituted phenyl-(C1-2 alkyloxy)-carbonyl, a C1-4 alkylcarbonyl or an optionally substituted phenyl-(C1-3 alkyl)-carbonyl group, n represents 1 or 0, Y represents, in the case when n=1, a tetrapeptide of general formula Y4-Y3-Y2-Y1, a tripeptide of general formula Y3-Y2-Y1 or a dipeptide of general formula Y2-Y1 or an amino acid residue of general formula Y1, or in the case when n=0, an alpha-hydroxyacyl-tripeptide of general formula Q4-Y3-Y2-Y1, an alpha-hydroxyacyl-dipeptide of general formula Q3-Y2-Y1 or an alpha-hydroxyacyl-aminoacyl residue of general formula Q2-Y1; wherein Y1-Y4 represent a residue selected from the group of the following L- or D-amino acids: alanine, alloisoleucine, cyclohexyl-glycine, phenyl-alanine, glutamine, histidine, isoleucine, leucine, lysine, methionine, pipecolic acid, proline, tyrosine and valine; and Q2-Q4 represent an acyl group selected from the following alpha-hydroxyacids of R or S configuration: 2-cycloheptyl-2-hydroxy-acetic acid, 2-cyclohexyl-2-hydroxyacetic acid, 3-cyclohexyllactic acid, 3-phenyllactic acid, 2-hydroxy-3-methylbutyric acid, 2-hydroxy-3-methylvaleric acid, mandelic acid or lactic acid, and salts thereof formed with organic or inorganic bases, and pharmaceutical compositions containing the same. The compounds of general formula (I) of the invention are valuable inhibitors of the interleukin-1beta converting enzyme.
Patent DK-0981343-T3 (DK)
Inventor: SOMERS PATRICIA K
IPC: A01N37/02
Filed: 1998-05-14
Granted: 2006-01-30
Abstract: This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases.
Patent DK-1082024-T3 (DK)
Inventor: HOFFMAN EARL ROGER
IPC: A23P1/10
Filed: 1998-05-29
Granted: 2005-07-11
Abstract: A process and apparatus for the continuous production, processing and packaging of a final chewing gum product. The product is extruded as a continuous tape or ribbon (44) of material, the material is flattened into an approximate final cross-sectional size and shape, and then inserted into a final sizing apparatus (48). The sizing apparatus maintains the gum product in its final cross-sectional size and shape. Thereafter, the continuous strip of final chewing gum product is scored, cut into individual pieces, and individually wrapped by a standard packaging machine (49-50). The individually wrapped pieces of gum can then be assembled into sets and packaged into packs of gum. <IMAGE>
Patent DK-0985718-T3 (DK)
Inventor: HUANG MISTY WEIYU
IPC: C09D183/04
Filed: 1999-09-07
Granted: 2006-05-08
Abstract: Emulsions comprising a water insoluble or semi-soluble silane or mixtures of such silanes have been found useful when used alone or formulated into aqueous primer systems to improve the adhesion of sealants, adhesives or coatings to a variety of substrates. These aqueous primers are suitable for both inorganic and organic substrates having either porous or non-porous surfaces. In many cases they have been found to outperform solvent based primers. Primers of this type can be used with a variety of waterbome or solvent based sealants, adhesives or coatings including acrylic or polyurethane latexes, high solid polyurethanes, epoxies and silicones. When used with waterborne systems, it is not necessary to wait for the primer to dry before application of the sealant, adhesive or coating.
Patent ES-2250030-T3 (ES)
Inventor: WUSCHIK GUNTER DIPL-ING
IPC: F21Y115/10
Filed: 2000-01-18
Granted: 2006-04-16
Abstract: The bathtub (2) has its interior illuminated using light sources (1) incorporated in the bath wall at spaced points, each using one or more LED's of similar or different type. The LED's may provide light in the red, green and blue spectral range, for providing light of each color of the visible spectrum, with simultaneous and/or individual control of the different LED's.
Patent ES-2328898-T3 (ES)
Title: Configuracion y procedimiento para la medicion simultanea de la velocidad asi como de la forma de la superficie de objetos que se mueven.
Inventor: DOEMENS GUNTER DR
IPC: G01S17/89
Filed: 2000-04-20
Granted: 2009-11-19
Abstract: Configuración para medir la velocidad o la forma de la superficie de objetos que se han movido (5) o una combinación de ello en base a mediciones de retardo de la luz, caracterizada por - al menos dos filas de sensores de semiconductor ópticos (1, 2) representados, de un conjunto de elementos de sensor (7) de resolución de lugar, distanciados entre sí y orientados en paralelo, así como dispuestos transversalmente respecto a la dirección de marcha de los objetos (5), con los que pueden tomarse perfiles de distancia de los objetos (5), - al menos una fuente de luz (6) posicionada en la zona de las filas de sensores de semiconductor (1, 2) para iluminar el objeto (5) con impulsos de luz.
Patent ES-2201993-T3 (ES)
Title: Cinta adhesiva de seguridad para detectar la apertura no autorizada de un embalaje.
Inventor: OTTEN ULRICH
IPC: C09J7/02
Filed: 2000-12-12
Granted: 2004-04-01
Abstract: Cinta adhesiva multicapa a base de una lámina termoplástica estirada, cuya cara superior puede estar recubierta con un barniz separador y cuya cara inferior lleva aplicadas las siguientes capas: (a) una capa de imprimación que no cubre toda la superficie, pero tiene muy buena adherencia sobre la lámina de termoplástico, (b) una capa separadora, de cubrición total, aplicada sobre la imprimación y la superficie libre de la lámina termoplástica, con mejor adherencia a la imprimación que a la lámina, (c) una masa adhesiva aplicada sobre toda la superficie de la capa separadora, cuya adhesión a la capa separadora es mejor que la adherencia de la capa separadora a la lámina termoplástica.
Patent ES-2201994-T3 (ES)
Inventor: VAN OCHTEN SANDER ANTONIE
IPC: A22C17/00
Filed: 2000-01-24
Granted: 2004-04-01
Abstract: The invention relates to a vent cutter (11,29) for separating a bung (36) and a carcass (3), comprising a jacket-like knife (30) and engaging means for engaging an anus (34) by insertion of a central core (32) into the anus, which engaging means after drilling out the anus are at least partly enveloped by the jacket-like knife, characterised in that, the core is displaceable in axial direction relative to the jacket-like knife, such that prior to drilling the core can be inserted into the anus, and after drilling out the core is at least partly enveloped by the jacket-like knife, whereby the anus is enclosed between the jacket-like knife and the outer end (33) of the core.
Patent ES-2246222-T3 (ES)
Inventor: ALTMANN FRIEDRICH
IPC: C12N15/11
Filed: 2000-02-17
Granted: 2006-02-16
Abstract: A DNA molecule (I), encoding a plant protein with fucosyl transferase activity, comprising a 2198 base pair sequence, fully defined in the specification, with an open reading frame of nucleotides 211-1740, a sequence at least 50 % homologous to it, a sequence hybridizing to it under stringent conditions, a sequence which differs due to genetic code degeneracy, or their complement, is new. Independent claims are also included for the following: (1) a DNA molecule (II), comprising a 105 base pair sequence, fully defined in the specification, a sequence at least 95 % homologous to it, a sequence that hybridizes to it under stringent conditions, or a sequence which differs due to genetic code degeneracy; (2) a DNA molecule which is a partial sequence of (I) or (II), which comprises 30-50 base pairs; (3) (I) or (II) covalently associated with a detectable marker substance; (4) a biologically functional vector comprising (I) or (II) or a partial sequence of at least 20 base pairs; (5) a biologically functional vector comprising (I), (II) or a partial sequence in inverse orientation to the promoter; (6) (I), (II) or the DNA molecule of (2) or (3) comprising a deletion, insertion and/or substitution mutation; (7) a DNA encoding a ribozyme, which comprises two sequence sections of at least 10-15 base pairs, which are complementary to (I) or (II), so that the ribozyme complexes with and cuts the mRNA, which is transcribed from a natural GlcNAc-alpha 1,3-fucosyl transferase DNA molecule; (8) a biologically functional vector comprising DNA of (6) or (7); (9) producing a cDNA of (I) or (II) comprising isolating RNA of insects or plants, and carrying out reverse transcription with a reverse transcriptase and primers; (10) cloning a GlcNAc-alpha 1,3-fucosyl transferase; (11) producing recombinant host cells which over-express GlcNAc-alpha 1,3-fucosyltransferase; (12) producing recombinant host cells, preferably plant or insect cells, which have a DNA of (6) in place of the non-mutated homologous sequence; (13) a recombinant plant or insect cell produced by the method of (12) and which over-expresses the GlcNAc-alpha 1,3-fucosyltransferase; (14) a PNA (peptide-nucleic acid) molecule which is complementary to or the same as (I); (15) producing a plant or insect cell with blocked GlcNAc-alpha 1,3-fucosyl transferase expression at the level of transcription or translation by the PNA of (14); (16) a method of recombinant glycoprotein production; (17) a recombinant glycoprotein produced in a plant or insect cell system as above; a GlcNAc-alpha 1,3-fucosyltransferase preparation, cloned by a method of (16), where the isoforms have a pI of between 6 and 9, preferably 6.8 and 8.2; and (18) producing human and other vertebrate carbohydrates by transplantation.
Patent ES-2329220-T3 (ES)
Title: Variantes mutantes del factor de crecimiento similar a insulina (igf) i.
Inventor: DUBAQUIE YVES
IPC: A61K38/00
Filed: 2000-01-05
Granted: 2009-11-24
Abstract: Una variante de IGF-1 que comprende una alanina en posición 3.
Patent ES-2202071-T3 (ES)
Inventor: NERESINI MASSIMO
IPC: A23J1/00
Filed: 2000-03-08
Granted: 2004-04-01
Abstract: Process for the disposal of solid or liquid wastes deriving from treatment operations of animal source materials, like lime baths or waste liquors from the processing of fish or meat or hides, with the recovery of useful or recyclable substances like sodium chloride and a peptide concentrate, and the release of purified waste liquors.
Patent ES-2208294-T3 (ES)
Inventor: KLEIN ROBERT-PETER
IPC: A61K31/46
Filed: 2000-03-09
Granted: 2004-06-16
Abstract: The invention relates to a transdermal therapy system (TTS) which comprises the following essential characteristics: a back layer which faces away from the skin and is impermeable to the active agent, at least one active agent deposit, a matrix which is connected to said active agent deposit and which controls the release of the active agent; and an adhesive fixing device for fixing the therapy system on the skin. The deposit and/or the matrix also contain support materials consisting of paper. The invention also relates to a method for producing the inventive transdermal therapy system and to the use of the same.
Patent ES-2264667-T3 (ES)
Inventor: IBAR JEAN-PIERRE
IPC: B29C48/525
Filed: 2000-06-12
Granted: 2007-01-16
Abstract: An apparatus and method for continuously reducing the viscosity of molten moldable polymeric material uses shear vibration under extensional flow to cause disentanglement. One or more station treatment cavities are defined by a gap composed of two closely separated surfaces in relative motion with each other at given speed and/or submitted to relative oscillations, with given frequency and amplitude to produce a shear deformation on the molten moldable material and a controlled variation of the gap dimension. The surface have a contour profile of ribs and/or bumps and/or grooves over which the molten moldable material can flow and/or can be dragged and/or is being pushed through and/or pumped through. The treatment cavities have an inlet through which the molten moldable material can pass into, and an outlet through which it can exit each treatment cavity.
Patent ES-2228559-T3 (ES)
Title: Inhibidores de la replicacion del virus respiratorio sincintial.
Inventor: JANSSENS FRANS EDUARD
IPC: C07D413/14
Filed: 2000-06-20
Granted: 2005-04-16
Abstract: Uso de un compuesto para la elaboración de un medicamento para tratar infecciones víricas, en el que el compuesto es un compuesto de fórmula N-óxido, sal de adición, amina cuaternaria o forma estereoquímicamente isomérica de estos, donde -a1=a2-a3=a4- representa un radical bivalente de fórmula -CH=CH-CH=CH- (a-1); -N=CH-CH=CH- (a-2); -CH=N-CH=CH- (a-3); -CH=CH-N=CH- (a-4); o -CH=CH-CH=N- (a-5); donde cada átomo de hidrógeno de los radicales (a-1), (a- 2), (a-3), (a-4) y (a-5) puede ser opcionalmente reemplazado por halo, C1-6-alquilo, nitro, amino, hidroxi, C1-6-alquiloxi, polihalo C1-6-alquilo, carboxilo, amino C1-6-alquilo, mono- o di(C1- 4alquil)amino C1-6-alquilo, C1-6-alquiloxi, carbonilo, hidroxi C1-6-alquilo.
Patent ES-2208423-T3 (ES)
Title: Herbicidas selectivos a base de una fenilsulfonilamino-carbonitriazolinona substituida y protectores.
Inventor: FEUCHT DIETER
IPC: A01N25/32
Filed: 2000-08-16
Granted: 2004-06-16
Abstract: Agente, que contiene un contenido activo de una combinación de productos activos que comprende (a) la 2-(2-metoxicarbonil-fenilsulfonilaminocarbonil)-4- metil-5-propoxi-2, 4-di-hidro-3H-1, 2, 4-triazol-3-ona de la fórmula (I), y/o una o varias sales del compuesto de la fórmula (I), especialmente la sal de sodio, y (b) el compuesto dietil-1-(2, 4-diclorofenil)-4, 5-dihidro- 5-metil-1h-pirazolo-3, 5-dicarboxilato (Mefenpyr- dietilo), correspondiendo, en general, a 1 parte en peso de un producto activo formado por la 2-(2-metoxicarbonil- fenilsulfonilaminocarbonil)-4-metil-5-propoxi-2, 4-dihi- dro-3H-1, 2, 4-triazol-3-ona de la fórmula (I), o sus sales, desde 0, 001 hasta 1.000 partes en peso de uno de los compuestos anteriormente citados del grupo (b).
Patent ES-2225250-T3 (ES)
Inventor: REDDIG THOMAS
IPC: B62D25/14
Filed: 2000-10-27
Granted: 2005-03-16
Abstract: The invention relates to a structural component for a motor vehicle, especially a stretcher to be used in the driver's compartment. The structural component ( 10 ) is configured as a lightweight component that comprises a shell-shaped base ( 12 ) and plastic reinforcement ribs ( 20, 26 ) molded onto said base. The aim of the invention is to provide an improved structural component that has the advantages of a lightweight component while being capable of fulfilling other functions in addition to its structural function. To this end, at least one channel ( 16 ) is completely or partially injection-molded into the interior ( 14 ) of the base ( 12 ) along with the reinforcement ribs ( 20 ).
Patent ES-2213658-T3 (ES)
Title: Palanca de cambio de velocidad para transmision automatica.
Inventor: MEDICO GIUSEPPE
IPC: B60K20/06
Filed: 2001-07-31
Granted: 2004-09-01
Abstract: Dispositivo selector de velocidad de una unidad de transmisión automática (3) incluyendo una caja de cambios (5) que se puede accionar por medio de unidades accionadoras (10a, 10b) controladas por una unidad de control electrónico (2); incluyendo el dispositivo selector (1): - primeros medios con una primera palanca (15) que se puede accionar manualmente y se puede mover entre al menos una posición de reposo (E) y una primera posición operativa (G) para ordenar un cambio a velocidad superior de la velocidad enganchada en dicha caja de cambios (5); - segundos medios con una segunda palanca (16) que se puede accionar manualmente y se puede mover entre al menos una posición de reposo (I) y una primera posición operativa (L) para ordenar un cambio a velocidad inferior de la velocidad enganchada en dicha caja de cambios (5), caracterizado porque al menos una de dicha primera palanca (15) o de dicha segunda palanca (16) se puede mover para lograr una segunda posición operativa (H; L) para generaruna señal respectiva (RET, FOL, SCAM, PREST) y ordenar en dicha unidad de transmisión automática (3) al menos una de las operaciones siguientes: - enganche de la marcha atrás; - disposición de la caja de cambios en punto muerto; - selección de un modo automático de operación de dicha unidad de transmisión automática; y - selección de un tipo ¿deportivo¿ de modo de operación de dicha unidad de transmisión automática.
Patent ES-2324281-T3 (ES)
Title: Eteres de dicarboxilato de calcio, procedimientos de fabricacion de los mismos.
Inventor: ANDO HOWARD YOSHIHISA
IPC: A61P3/10
Filed: 2001-01-11
Granted: 2009-08-04
Abstract: El compuesto sal hidratada monocálcica del ácido 6-(5-carboxi-5-metil-hexiloxi)-2,2-dimetilhexanoico de forma cristalina 1 que presenta un diagrama de difracción de rayos X de polvo que comprende picos en 6,760, 8,183, 8,560, 9,239, 9,760, 10,569, 11,141, 13,760, 15,599, 16,740, 17,420, 20,639, 21,391, 22,139 y 31,559 grados de 2-teta o presenta un espectro de RMN 13 C de estado sólido que comprende desplazamientos en 189,6, 186,2, 71,4, 43,4, 30,1, 28,4, 25,2 y 23,1 ppm.
Patent ES-2225480-T3 (ES)
Title: Grupo de suelo de un vehiculo automovil.
Inventor: HARRER PETER
IPC: B60K13/06
Filed: 2001-01-05
Granted: 2005-03-16
Abstract: Grupo de suelo (1) de vehículo automóvil con parte de bajos (2) e instalación de gases de escape (3), en el que los bajos (2) presentan al menos un entrante cuya limitación superior corresponde al contorno superior (4) de al menos una parte de la instalación de gases de escape (3), caracterizado porque los bajos (2) son parte de la instalación de gases de escape (3) en al menos algunas zonas.
Patent ES-2315277-T3 (ES)
Inventor: ROMAN GIANFRANCO
IPC: B05B15/74
Filed: 2001-02-20
Granted: 2009-04-01
Abstract: A watering nozzle (16) for underground pop-up sprinkler (1) comprises a bottom part (17) and a top part (37) comprising a distribution cylinder (40). The bottom part (17) is provided with an annular opening (100) that receives the flow of water coming from the base of the sprinkler (1) and generates a jet in the form of a spray having pre-established angular extension that flows into a distribution cylinder (40) provided with radial slots (41) arranged as an arc of circumference that proceed from its bottom to its side wall so as to subdivide the single spray jet into single jets. The distribution cylinder (40) has on top a fan wheel (70) having a diameter greater than the cylinder and provided with external fins (71) that extend downward. The distribution cylinder (40) rotates under the action of the single jet of water on the walls of said radial slots and by a set of gears (200) the fan wheel (70) is made rotate in opposite sense as compared with the cylinder (40) in such a way that the various jets of water coming out of the slots (41) are deviated in radial direction.
Patent ES-2217137-T3 (ES)
Title: Optimizacion de la correccion por ablacion de un sistema optico.
Inventor: CAMPIN JOHN ALFRED
IPC: A61N5/06
Filed: 2001-03-22
Granted: 2004-11-01
Abstract: Sistema de corrección óptica (10) para corregir defectos visuales de un ojo (120), comprendiendo el sistema de corrección óptica: una fuente de luz (12) para generar un haz (18) de radiación óptica; una óptica de enfoque (22) dispuesta en la trayectoria del haz para dirigir el haz a través del ojo, en el que el haz se refleja en la retina (122) del ojo en forma de un frente de onda (24) de radiación que emana del ojo; un analizador de frente de ondas (26) sensible al frente de onda que emana del ojo para determinar la diferencia de caminos ópticos entre una onda de referencia (110) y el frente de onda; un convertidor para calcular una corrección óptica basada en la diferencia de caminos ópticos; un sistema láser de tratamiento (500) para emitir un haz láser (502) que tiene suficiente potencia para la ablación de material corneal (126), consiguiéndose la corrección óptica mediante la extracción de una cantidad seleccionada de material corneal para modificar la forma de la córnea según lo requerido.
Patent ES-2296756-T3 (ES)
Inventor: BERKHOUT MARCO
IPC: H03F3/26
Filed: 2001-05-03
Granted: 2008-05-01
Abstract: The invention relates to a push-pull amplifier having a silent start circuit. To overcome the problem of noise during start up the amplifier of the invention comprises a silent start circuit, which decides the "perfect" moment to start the power switches without the known start-up noise.
Patent ES-2231527-T3 (ES)
Title: Electrovalvula biestable.
Inventor: KORDON ROLF
IPC: F16K27/04
Filed: 2001-07-26
Granted: 2005-05-16
Abstract: Electroválvula, en particular para una máquina de frío, con un cuerpo de válvula (13) con una entrada (35) y dos salidas (33) y un elemento de válvula (31) que se puede desplazar dentro del cuerpo de la válvula (13) entre dos posiciones extremas que se corresponden respectivamente a distintas posiciones de conmutación de la electroválvula, con por lo menos un imán permanente (36) para mantener el elemento de válvula (31) en la posición extrema respectiva que haya adoptado, así como un solenoide (9) para ejercer sobre el elemento de válvula (31) una fuerza magnética que provoque su desplazamiento a la otra posición extrema respectiva, caracterizada porque el cuerpo de la válvula (13) y el solenoide (9) se alojan en dos compartimientos preconformados de una carcasa (1, 40) de material no magnético, y porque el por lo menos un imán permanente (36) va sujeto en una montura en una pared de la carcasa, orientado hacia una posición central del elemento de válvula (31) situado entre las dos posiciones extremas.