baber/WOPTO huggingface dataset:
Patent AU-2019280394-A1 (AU)
Title: CRISPR-Cas component systems, methods and compositions for sequence manipulation
Inventor: ZHANG FENG
IPC: C12N15/63
Filed: 2019-12-16
Abstract: The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for selecting specific cells by introducing precise mutations utilizing the CRISPR/Cas system.
Patent AU-2019283842-A1 (AU)
Title: Devices and methods for pairing between a wireless control device and electronic unit
Inventor: PETTINOTTO GILLES
IPC: H04W12/00
Filed: 2019-12-18
Abstract: This method for operating a wireless control device comprises: 
- the starting up (20) of a control circuit following the actuation, by a user, of a 
control unit coupled to an energy harvesting device to recharge an energy reserve 
which electrically powers the control device; 
- the sending (30) of a control message including a control command; 
- the comparison (32) of the elapsed time since the starting up of the control circuit 
with a first threshold value; 
- when the elapsed time is greater than or equal to the first threshold value, the 
sending (40) of a pairing request message to the electronic unit.
2/9 
-20
-3626 
-38-
-42
FIG.2
Patent AU-2019297439-A1 (AU)
Title: Vascular and aortic grafts and deployment tool
Inventor: PALERMO THOMAS J
IPC: A61F2/97
Filed: 2019-07-03
Abstract: A containment structure for use with a workpiece vascular graft may include a sheath having two lateral edges; holes defined through the sheath in proximity to the lateral edges of the sheath, wherein longitudinally-adjacent holes are spaced longitudinally from one another; and a pull wire extending through the holes. A medical apparatus may include a vascular graft self-expandable from an insertion state to a deployed state; and a suture cuff located at one end of the vascular graft. A deployment tool may include a mandrel; a vascular graft placed about the mandrel, and a sheath wrapped about the vascular graft, wherein the sheath compresses the vascular graft to an insertion diameter. A hybrid graft may include a graft and a stent, where an end of the graft is affixed to an end of the stent.
Patent AU-2019321669-A1 (AU)
Title: Medical pump
Inventor: BAIER MICHAEL J
IPC: A61M5/145
Filed: 2019-08-16
Abstract: A pump for treating a patient is disclosed that includes a spring- biased plunger 116 biased toward actuation against a tube 216; a cam shaft 190 configured to actuate the spring-based plunger; a lever 104 actuatable between a closed position and an open position; a shaft coupled to the lever, the shaft having a central axis centrally along the length of the shaft, the shaft 118 coupled to the lever to rotate around the central axis in accordance with actuation of the lever; and a lift cam 120 pivotally coupled to the shaft, wherein the lift cam pivots around a lift cam axis, the lift cam axis of the lift cam is parallel to the central axis of the shaft, and the lift cam engages with the spring-based plunger to lift the spring-biased plunger off of the cam shaft as the shaft rotates in accordance with actuating the lever to the open position.
Patent AU-2019341645-A1 (AU)
Title: Impedance flow cytometry apparatus
Inventor: MORGAN HYWEL
IPC: B01L3/00
Filed: 2019-09-16
Abstract: Impedance flow cytometry apparatus comprises: a flow channel for carrying a flow of fluid comprising particles suspended in an electrolyte from an inlet to an outlet; a first electrode group and a second electrode group, each electrode group providing first and second current paths through fluid flowing in the flow channel; wherein each electrode group comprises: a first signal electrode to provide to the first current path a first electrical signal of frequency, magnitude and phase; a second signal electrode to provide to the second current path a second electrical signal of substantially equal frequency and magnitude as the first electrical signal and of opposite phase to the first electrical signal; and one or more measurement electrodes to detect current flow in the first current path and the second current path and produce a summed signal representing the sum of the current flow in the first current path and the current flow in the second current path; wherein the first electrode group produces a first summed signal and the second electrode group produces a second summed signal; and circuitry to determine a differential signal representing the difference between the first summed signal and the second summed signal.
Patent AU-2019369933-A1 (AU)
Title: Easily-expandable wave-dissipating block having artificial fish reef function
Inventor: LEE JUNG WOO
IPC: A01K61/70
Filed: 2019-10-29
Abstract: The present invention relates to a wave-dissipating block comprising: a body which is placed on a seabed in a vertical direction and which is in the shape of a polygonal column, a cylinder, an oval column, a cross column and the like; male coupling protrusions respectively provided on a side surface of the body in a height direction and on the other surface facing same; female coupling grooves respectively provided on the side surface of the body in the height direction and on the other surface thereof facing same, and provided in a shape corresponding to the male coupling protrusion; a habitat part formed as a space provided in a center portion of the body or a portion of the body so as to enable seawater to pass therethrough or remain therein, thereby having a fish and shellfish habitat and wave-dissipating function; a partition provided as a plate for separating the habitat part, so as to provide structural stability to the body and provide a habitat environment for fish and shellfish; a through-hole formed at the partition so as to connect the habitat parts so that the habitat parts can communicate with each other, thereby enabling the movement of fish and shellfish and the flow of the seawater; and a space part, which forms the space between the plurality of bodies connected adjacently to each other, so as to enable the seawater to pass therethrough or stay therein, thereby having the fish and shellfish habitat and wave-dissipating function, wherein a plurality of insertion protrusions are provided on the outer surface of the body or the inner surface of the body for dividing the habitat part, and insertion grooves are formed between the plurality of insertion protrusions, and the male coupling protrusion is inserted into the female coupling groove so that the wave-dissipating blocks can be extended in the horizontal and vertical directions on the seabed.
Patent AU-2019372057-A1 (AU)
Title: 2-amino-N-heteroaryl-nicotinamides as NAV1.8 inhibitors
Inventor: ARASAPPAN ASHOK
IPC: C07D417/14
Filed: 2019-10-31
Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are inhibitors of Nav1.8 channel activity and may be useful in the treatment, prevention, management, amelioration, control and suppression of diseases mediated by Nav1.8 channel activity. The compounds of the present invention may be useful in the treatment, prevention or management of pain disorders, cough disorders, acute itch disorders, and chronic itch disorders.
Patent AU-2019386373-A1 (AU)
Title: Internal structure of a robotic surgical instrument
Inventor: GROVER SIMON RODERICK
IPC: A61B34/30
Filed: 2019-11-29
Abstract: A robotic surgical instrument comprising a shaft, an end effector, and an articulation connecting the end effector to a distal end of the shaft. The articulation comprises joints permitting the end effector to adopt a range of orientations relative to a longitudinal axis of the shaft. Pairs of driving elements drive the joints, the driving elements extending through the shaft to the joints. An additional element extends through the shaft to the end effector via the articulation. A resilient barrier inside the shaft extends over a cross-sectional area of the shaft, the pairs of driving elements and the additional element passing through the resilient barrier, the resilient barrier being in resilient contact with the additional element so as to provide a resilient force opposing movement of the additional element; wherein each driving element of the pairs of driving elements passes through a hole in the resilient barrier without contacting the resilient barrier.
Patent AU-2019400521-A1 (AU)
Title: Modified Homoserine Dehydrogenase And Method For Producing Homoserine Or L-Amino Acid Derived From Homoserine Using The Same
Inventor: KWON SU YON
IPC: C12P13/08
Filed: 2019-04-10
Abstract: The present application pertains to a modified homoserine dehydrogenase, and a method for producing homoserine or a homoserine-derived L-amino acid using same.
Patent WO-2022056572-A1 (WO)
Title: Treatment of solid tumours
Inventor: POH ASHLEIGH REN-YI
IPC: A61K39/395
Filed: 2020-09-18
Abstract: The present invention relates to a method for the treatment of cancer, in particular colorectal cancer (colon cancer), comprising administering an effective amount of dasatinib to the subject; and administering an effective amount of an immune checkpoint inhibitor to the subject. Preferably said immune checkpoint inhibitor is selected from the group consisting of a PD-1 inhibitor, a PD-L1 inhibitor and a CTLA-4 inhibitor, such as pembrolizumab, nivolumab, cemiplimab, atezolizumab, avelumab, durvalumab and ipilimumab.
Patent AU-2020202254-A1 (AU)
Title: The production and use of red blood cells
Inventor: TURNER BRIAN CURTIS
IPC: A01N63/00
Filed: 2020-03-30
Abstract: The present disclosure relates to the production of red blood cells from hematopoietic stem cells, by differentiating such cells in the presence of a protein that induces cell survival and proliferation.
Patent AU-2020202606-A1 (AU)
Title: Soft, absorbent sheets having high absorbency and high caliper, and methods of making soft, absorbent sheets
Inventor: CHOU HUNG LIANG
IPC: B32B29/02
Filed: 2020-04-17
Abstract: A method of making a paper product, the method comprising: forming an aqueous cellulosic web on a structuring fabric in a papermaking machine; non-compactively dewatering the cellulosic web on the structuring fabric; and drying the cellulosic web to form the paper product, wherein the portion of the structuring fabric on which the cellulosic web is formed has an adjusted planar volumetric index of at least about 27.
Patent AU-2020203328-A1 (AU)
Title: Wall footing formwork structure
Inventor: PSZCZONKA DANIEL
IPC: E04G9/05
Filed: 2020-05-21
Abstract: A footing formwork structure for constructing a footing with a flowable curable material 
like concrete, the footing formwork structure including: a base; a top portion; and at 
least one support extending between the base and top portion; wherein the base and 
top portion substantially define a footing volume therebetween, and wherein the top 
portion includes a wall mount region above which at least one wall formwork element is 
to be mounted, the wall mount region including at least one aperture therein such that, 
on depositing curable material into a mounted wall formwork element, the curable 
material is permitted to flow through the at least one aperture into the footer volume.
1/4 
Figure 1 
1 3 7 
89 
12 
11 
4 5 6 
10 2 10 
12 
11
Patent AU-2020207880-A1 (AU)
Title: Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide
Inventor: MOLLARD PAUL
IPC: A61P25/28
Filed: 2020-07-24
Abstract: Disclosed herein are polymorphic and amorphous forms of anhydrate, hydrate, and 
solvates of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4
dienyl)butanamide and methods of using such compositions for treating or suppressing oxidative 
stress disorders, including mitochondrial disorders, impaired energy processing disorders, 
neurodegenerative diseases and diseases of aging. Further disclosed are methods of making such 
polymorphic and amorphous forms.
Patent AU-2020210201-A1 (AU)
Title: Shielding device and method
Inventor: WAHNSCHAFFE DOUGLAS SCOTT
IPC: A61B6/10
Filed: 2020-07-29
Abstract: Some embodiments of a shielding device can include a base and a shield coupled to 
the base. The shielding device can be used to provide protection for a healthcare worker 
(e.g., physician, nurse, technician) during a medical procedure.  
1
Patent AU-2020210811-A1 (AU)
Title: Reconstitution system to administer a drug via a high vacuum vial with integrated vent conduit
Inventor: DESBROSSES FREDDY
IPC: A61J1/20
Filed: 2020-01-21
Abstract: A reconstitution device includes a body, a first piercing member located at a first end of the body, and a receptacle located at the second end of the body. The receptacle includes a collar configured to engage a vial, and a cap extending from the collar and holding a second piercing member. The second piercing member is disposed within the collar. The reconstitution device includes a first fluid pathway formed within and extending from the first piercing member to the second piercing member. The reconstitution device includes a second fluid pathway formed within and extending from the second piercing member to a portion of the body between the first piercing member and the second piercing member.
Patent AU-2020253878-A1 (AU)
Title: Quantum logic gate design and optimization
Inventor: DEBNATH SHANTANU
IPC: G06N10/00
Filed: 2020-01-27
Abstract: A method of performing an entangling operation in a chain of trapped ions includes selecting a gate duration value and a detuning value of a pulse sequence used to perform an entangling gate operation on a first ion and a second ion, measuring frequencies of collective motional modes of the chain, computing a value of an entangling interaction between the first and second ions and values of phase space trajectories of the collective motional modes, based on the selected gate duration value, the selected detuning value, and the measured frequencies of the collective motional modes, determining an intensity of each pulse segment in the pulse sequence based on the computed values, generating the pulse sequence by connecting the pulse segments, each pulse segment having the determined intensity and a pulse shape with ramps formed using a spline, and applying the generated pulse sequence to the first and second ions.
Patent AU-2020254710-A1 (AU)
Title: A lid for a container
Inventor: COLEGATE MATTHEW
IPC: A47G19/22
Filed: 2020-04-03
Abstract: A lid for a container is disclosed. The lid includes body which is engageable with a container to form a liquid-tight seal and which has an opening for discharging liquids from the container. The lid also has a closure that is adapted to connect with the lid such that the closure is operable to close the opening to prevent liquid discharge and to be positioned clear of the opening to permit liquid discharge through the opening. The closure is releasably securable in the position clear of the opening by engaging a securing formation on the body. Alternatively, the lid has a discharge opening which has a formation for receiving an accessory and a storage cavity for receiving an accessory. wherein the formations of the opening and the storage cavity are the same so that accessories having a complementary formation are interchangeable between the opening and the storage cavity.
Patent AU-2020271997-A1 (AU)
Title: Respiratory pressure therapy system
Inventor: KENYON BARTON JOHN
IPC: F04D29/24
Filed: 2020-04-10
Abstract: A respiratory pressure therapy (RPT) system may include a housing portion forming a plenum chamber pressurizable to a therapeutic pressure; a seal-forming structure constructed and arranged to with a region of the patient's face; a positioning and stabilising structure constructed and arranged to provide an elastic force to hold the seal-forming structure in a therapeutically effective position on the patient's head; a blower configured to pressurize the plenum chamber to the therapeutic pressure; a vent assembly configured to discharge gas from a plenum chamber to atmosphere; a sensor port positioned downstream of the vent assembly such that the sensor port is in pneumatic communication with the air within the plenum chamber in any position of the vent assembly; and a sensor in pneumatic communication with the air within the plenum chamber via the sensor port.
Patent AU-2020273228-A1 (AU)
Title: Chemical synthesis plant
Inventor: DE SARKAR SUDIP
IPC: C25B1/04
Filed: 2020-04-03
Abstract: A plant, such as a hydrocarbon plant, is provided, which consists of a syngas stage for syngas generation and a synthesis stage where said syngas is synthesized to produce syngas derived product, such as hydrocarbon product. The plant makes effective use of various streams; in particular CO
Patent AU-2020277178-A1 (AU)
Title: Evaluation and treatment of bradykinin-mediated disorders
Inventor: SEXTON DANIEL J
IPC: C07K16/40
Filed: 2020-11-25
Abstract: EVALUATION AND TREATMENT OF BRADYKININ-MEDIATED 
DISORDERS 
ABSTRACT 
The present disclosure provides methods of evaluating a subject, e.g., a subject at risk for or 
suffering from a pKal-mediated or bradykinin-mediated disorder, based on values (e.g., 
percentages) of intact and/or cleaved kininogen in a sample of the subject. Provided methods 
permit analysis of patients with plasma kallikrein-mediated angioedema (KMA), or other 
diseases mediated by pKal useful in the evaluation and treatment. Such methods can involve the 
use of a detection agent that preferentially binds cleaved kininogen or intact kininogen.
Patent AU-2020283505-A1 (AU)
Title: Heterocyclic compounds as PRMT5 inhibitors
Inventor: WU WEN-LIAN
IPC: A61K31/4725
Filed: 2020-05-27
Abstract: The present disclosure describes novel heterocyclic PRMT5 inhibitors and methods for preparing them. The pharmaceutical compositions comprising such PRMT5 inhibitors and methods of using them for treating cancer, infectious diseases, and other PRMT5 associated disorders are also described.
Patent AU-2020291159-A1 (AU)
Title: Modular tube and method of manufacturing
Inventor: CHAMBERS DAVID
IPC: F16L9/22
Filed: 2020-06-11
Abstract: A tube for use as part of a structural support pole, and a method for manufacturing a tube, comprising a plurality of tube perimeter sections, wherein each tube perimeter section of the first plurality of tube perimeter sections is formed by pultrusion, each tube perimeter section of the first plurality of tube perimeter sections having the same pultrusion cross-sectional shape, and wherein each tube perimeter section comprises: an outer surface; an inner surface; a side surface; and a cavity between the inner surface and the outer surface, wherein the cavity extends through the tube perimeter section. The side surface is adapted to be fastened to an adjacent side surface of an adjacent tube perimeter section, thereby to form an annular arrangement of tube perimeter sections. The tube further comprises a first filament, wherein the first filament is wound about the outer surfaces of the first plurality of tube perimeter sections arranged in an annular arrangement.
Patent AU-2020292563-A1 (AU)
Title: Instruments for delivering bone cement to a bone screw
Inventor: EMIL CORY
IPC: A61B17/70
Filed: 2020-06-03
Abstract: Instruments and methods for delivering bone cement are disclosed herein. In one exemplary embodiment, the instrument includes a cannulated bone screw having a head that is configured to be received within a rod receiver and a shank extending distally from the head and configured to extend distally from the rod receiver, a cannulated shaft having a distal end configured to extend into the shank of the cannulated bone screw and a proximal end configured to couple to a bone cement delivery system, and a retaining sleeve disposed around at least a portion of the cannulated shaft. The head of the bone screw has proximal and distal recesses therein, and a distal end of the retaining sleeve is configured to couple to the proximal recess.
Patent AU-2020295796-A1 (AU)
Title: Combination of hepatitis B virus (HBV) vaccines and HBV-targeting rnai
Inventor: HORTON HELEN
IPC: A61K39/12
Filed: 2020-06-18
Abstract: Therapeutic combinations of hepatitis B virus (HBV) vaccines and an RNAi agent for inhibiting the expression of an HBV gene are described. Methods of inducing an immune response against HBV or treating an HBV-induced disease, particularly in individuals having chronic HBV infection, using the disclosed therapeutic combinations are also described.
Patent AU-2020296239-A1 (AU)
Title: Magnet in bolt
Inventor: CEDERBLAD MATS
IPC: E05B47/00
Filed: 2020-06-16
Abstract: It is provided a lock assembly comprising: a striking plate assembly comprising an aperture and a magnetometer arranged in proximity of the aperture; a bolt being displaceable to enable movement through the aperture of the striking plate assembly, the bolt comprising a magnet; and a sensor device for detecting proximate presence of an object, wherein the sensor device is configured to power up the magnetometer when the sensor device detects proximate presence of an object; wherein the lock assembly is configured to detect, using the magnetometer and magnet when the bolt is in a protruded position through the aperture.
Patent AU-2020298124-A1 (AU)
Title: Flexible pipe for transporting a fluid in a submarine environment and associated inspection method
Inventor: ALVES PINTO MOSQUEIRA GOMES CRISTIANO
IPC: F16L33/01
Filed: 2020-06-22
Abstract: The invention relates to a flexible conduit for transporting a fluid in a submarine environment, suitable for being inspected by an ultrasonic control method for detecting the presence of water in the annular space.
Patent AU-2020301720-A1 (AU)
Title: Turbulence monitoring and forecasting systems and methods
Inventor: GRACE WARWICK
IPC: G01W1/06
Filed: 2020-06-25
Abstract: Embodiments generally relate to systems and methods for determining and/or forecasting local atmospheric stability and/or turbulence. This information can then be used to inform decisions regarding crop spraying, such as whether the atmospheric conditions are sufficiently turbulent to avoid airborne spray fines drifting in an undesirable manner, for example. Some embodiments relate to a spray drift hazard alert system comprising a data logger. The data logger is configured to: receive local meteorological observation data from one or more sensors at a location; analyse the data to determine a local vertical turbulence characteristic indicative of a current level of vertical turbulence at the location; compare the vertical turbulence characteristic with a predetermined threshold of the vertical turbulence characteristic; and transmit information to a client device indicating whether local meteorological conditions are suitable for crop spraying based on the comparison between the vertical turbulence characteristic and the predetermined threshold.
Patent AU-2020308965-A1 (AU)
Title: Underwater glider
Inventor: ALLUM RONALD CHARLES
IPC: B63G8/00
Filed: 2020-06-26
Abstract: In an underwater glider, stability and versatility can be enhanced by the use of a high wing design. In a high wing design, a centerline of the wings extending from the sides of the body of the glider are located above a relative centerline of the body of the glider. The relative centerline of the wings may rise continuously from a region where the wings attach to the body to respective ends of the wings. In particular for a blended wing glider, a top surface of the glider is level in a line extending between ends of each wing.