baber/WOPTO huggingface dataset:
Patent NZ-554383-A (NZ)
Title: Dose display mechanismn for drug delivery device
Inventor: SAIKI MASARU
IPC: A61M5/315
Filed: 2005-09-14
Abstract: A drug dose display mechanism for an adjustable pen type injector comprising a dose setting control knob 22 and a counter ring 30 with the dose setting control knob 22 having on it's external surface a helical thread 111 and longitudinal grooves 64. Both the helical thread 111 and the longitudinal grooves 64 run from the proximal end of the dose setting control knob 22 to the distal end of the dose setting control knob 22. The counter ring 30 has projections 63 on its inner surface that interlock with the longitudinal grooves 64 on the dose setting control knob. This interlocking between the projections 63 on the inner surface of the counter ring 30 and the longitudinal grooves 64 on the dose setting control knob permits the counter ring 30 only longitudinal movement along the dose setting control knob 22.
Patent NZ-556541-A (NZ)
Title: Compositions and methods for promoting wound healing and tissue regeneration using polypetide sequences from an alpha connexin
Inventor: GOURDIE ROBERT
IPC: A61K38/08
Filed: 2005-12-20
Abstract: Provided is a composition comprising at least one polypeptide consisting of the carboxy-terminal most 4 to 30 contiguous amino acids of an alpha connexin protein or conservative variant thereof, wherein said at least one alpha connexin polypeptide is linked at its amino terminus to a cellular internalization transporter. The composition can be used to treat various wounds and tissue injuries.
Patent NZ-565761-A (NZ)
Title: A support for concrete reinforcing
Inventor: DE MUELENAERE ALEX
IPC: E04C5/16
Filed: 2008-02-07
Abstract: This discloses an apparatus 10 for supporting concrete reinforcement above a base surface 24 and for spacing adjacent cavity formers apart to define a channel 9 between the cavity formers and for positioning the adjacent cavity formers 4 in relation to edge formwork to define a perimeter, footing between the cavity formers and the edge formwork for forming a concrete slab. The apparatus 10 comprises a body for contacting the edge formwork and the adjacent cavity formers in use of the apparatus to space the cavity formers from each other and from the perimeter formwork such that movement of one or both of the cavity formers is restricted, with the body comprising contact members for engaging respective adjacent sides 4 of each cavity former at a corner of the cavity former 46, and also a support means 30 for supporting concrete reinforcement above the base surface in the footing in use of the apparatus and a support means for supporting concrete reinforcement above the base surface in the channel in use of the apparatus such that the reinforcement is embedded in the concrete slab when wet concrete is poured to form the slab.
Patent NZ-565953-A (NZ)
Title: Small compounds that correct protein misfolding and uses thereof
Inventor: KAUSHAL SHALESH
IPC: C12N5/071
Filed: 2006-07-27
Abstract: Disclosed is a pharmaceutical composition comprising a proteasomal inhibitor selected from the group consisting of MG-132, lactocystin, clastolactocystin beta lactone, PSI, MG-115, MG101, N-acetyl-Leu-Leu-Met-CHO, N-carbobenzoyl-Gly-Pro-Phe-Leu-CHO, N-carbobenzoyl-Gly-Pro-Ala-Phe-CHO, N-carbobenzoyl-Leu-Leu-Phe-CHO or salts thereof, in combination with a compound selected from the group consisting of 11-cis-retinal, 9-cis-retinal or a 7-ring locked isomer of 11-cis retinal for the treatment of a disease or condition selected from the group consisting of retinitis pigmentosa, age-related macular degeneration, glaucoma, corneal dystrophies, retinoschises, Stargardt's disease, autosomal dominant druzen and Best's macular dystrophy.
Patent NZ-566327-A (NZ)
Title: Method for producing superconducting wire by electroplating copper onto a silver stabilisation layer
Inventor: UEYAMA MUNETSUGA
IPC: H01B12/06
Filed: 2006-08-30
Abstract: A method of fabricating a superconducting wire is disclosed. The steps of the method are: forming a superconducting layer (3) on a substrate (1) or an intermediate layer (2) formed on the substrate (1); forming a silver stabilization layer (4) on said superconducting layer (3); immersing the substrate (1) in a copper sulphate solution (7) after the superconducting layer (3) and the silver stabilization layer (4) are formed; and forming a copper stabilization layer on the silver stabilization layer (4) by electroplating with the copper sulphate solution in a plating bath (8). The silver stabilization layer (4) is formed to a thickness not more than 5 um and the copper stabilization layer is formed to a thickness of at least 10 um.
Patent NZ-566863-A (NZ)
Title: Intermediate for the manufacture of valsartan
Inventor: HIRT HANS
IPC: C07D257/04
Filed: 2003-09-22
Abstract: Disclosed is a process for the manufacture of the compound of formula (IIa') or a salt thereof, comprising: (i) reacting, in the presence of an acid, a compound of formula (IV a) or a salt thereof, wherein Hal is halogen with a compound of formula (IV b) wherein R6, R7 and R8 independently of one another, are selected from H or alkyl, and R9 is alkyl, or R7 and R9 together form C2-C5 alkylene; or R6 and R8 together form C3-C6 alkylene; (ii) reacting in the presence of a transition metal catalyst, a resulting compound of formula (IVc) with a compound of formula (IV d) wherein X is halogen, and R5 and R'5 are alkyl or together form C2-C4 alkylene (iii) Removing, sequentially or in a single step the protecting groups from a resulting compound of formula (IV e) by treatment with an acid; and (iv) Isolating a resulting compound of formula (IIa') or a salt thereof. Also disclosed are compounds of formula (IV e) which are useful intermediates in the production of the angiotensin receptor blocker valsartan. (62) Divided Out of 538927
Patent NZ-574238-A (NZ)
Title: Vaccines for malaria
Inventor: COHEN JOSEPH D
IPC: A61K39/015
Filed: 2007-07-16
Abstract: Disclosed is an immunogenic protein particle comprising the following monomers: a. a fusion protein comprising at least one repeat unit from the central repeat region of type I circumsporozoite (CS) protein of P.vivax, at least one repeat unit from the central repeat region of a type II CS protein of P.vivax and the S antigen of Hepatitis B (CSV-S), and b. a fusion protein comprising at least four repeat units of the central repeat region of CS protein of P. falciparum and S antigen of Hepatitis B (RTS), and c. optionally the S antigen from Hepatitis B. Also disclosed are compositions comprising the particle with an adjuvant.
Patent NZ-574619-A (NZ)
Title: THIADIAZOLIDINEDIONE DERIVATIVES including 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (TDZD-8)
Inventor: JORDAN CRAIG
IPC: A61K31/41
Filed: 2007-07-18
Abstract: Disclosed is the use of a compound of Formula (I), or a salt, prodrug, hydrate, solvate or polymorph thereof in the preparation of a medicament for treatment or prevention of a disorder in a subject selected from blood cancers (such as leukaemia) and hematologic malignancies; wherein: A is -C(R1)2-, -O- or -NR1-; E is -NR1; G is -S-, -NR1- or -CR1R2-; R1 and R2 are each independently selected from hydrogen, alkyl, cycloalkyl, haloalkyl, aryl, heteroaryl, -(Z)n-aryl, -OR3, -C(O)R3, -C(O)OR3, -(Z)n-C(O)OR3 and -S(O)t-; Z is independently selected from -C(R3)(R4)-, -C(O)-, -O-, -C(=NR3)-, -S(O)t- and -N(R3)-; n is zero, one or two; t is zero, one or two; R3 and R4 are each independently selected from hydrogen, alkyl, aryl and heterocyclic; and X and Y are each independently selected from O, S, N(R3) and C(R1)(R2). Of particular importance is the use of a compound of formula (I) which is 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (also known as TDZD-8).
Patent NZ-585674-A (NZ)
Title: Vaccination with multiple clades of h5 influenza a virus
Inventor: PODDA AUDINO
IPC: A61K39/145
Filed: 2008-11-25
Abstract: 585674 Disclosed is the use of a plurality of influenza virus antigens in the manufacture of a medicament for vaccinating a subject against multiple clades of H5, influenza virus, said multi-dose medicament comprising a first dosage unit comprising hemagglutinin antigen from a first clade of H5 influenza A virus and a second dosage unit comprising hemagglutinin antigen from a second clade of H5 influenza A virus, wherein the first and second clades are different from each other. Further disclosed is the use of an immunogenic composition comprising hemagglutinin antigen from a second clade of H5 influenza A virus in the manufacture of a medicament for vaccinating against multiple clades of H5 influenza virus in a subject immunized previously with an immunogenic composition comprising hemagglutinin from a first clade of H5 influenza A virus. Also disclosed is an immunogenic composition for vaccinating a subject against multiple clades of H5 influenza virus, said immunogenic composition comprising hemagglutinin antigens from more than one clade of H5 influenza virus, and a kit comprising said composition.
Patent NZ-586358-A (NZ)
Title: Synergistic sweetening compositions comprising sucralose and a purified extract of stevia
Inventor: CATANI STEVEN J
IPC: A23L27/30
Filed: 2008-12-19
Abstract: 586358 Disclosed herein is a synergistic sweetening composition consisting of: sucralose and a purified extract of stevia, wherein the purified extract of stevia is about 40% to about 100% pure, and wherein the purified extract of stevia comprises a combination of rebaudiosides and dulcosides. Specifically wherein the purified extract of stevia is selected from the group consisting of rebaudioside A, rebaudioside B, rebaudioside C, rebaudioside D, rebaudioside E, dulcoside A, dulcoside B, and combinations thereof. Additionally disclosed is a method of making a food or beverage product comprising said synergistic sweetening composition in a food or beverage product, such as a carbonated soft drink, tea and coffee.
Patent NZ-590105-A (NZ)
Title: Duct such as tee, with strap against shoulder of duct end being adjustable for transport and tightened conditions of strap, while maintaining strap captive to duct system, with two chambered female buckle portion
Inventor: DUELL GRAHAM NORMAN
IPC: F16B7/04
Filed: 2009-06-04
Abstract: 590105 A duct system component has a hollow body (12), a generally tubular duct connection element that projects from the body (12) and has an outer end (28). A band of integral continuous or intermittent outstanding formation(s) (24) extend about the tubular duct connection element at a position spaced from said outer end (28) thereof, and from said body. The component further includes strap means (60) retained or adapted to be retained in a closed transport condition on said connection element (21) between said body (12) and said band (24) so that it cannot slip over the band (24), which strap means (60) is selectively adjustable from said transport condition to a loose fitting but closed condition for fitment over a duct into which said connection element is receivable, and then to a tight in-use condition in which the strap means (60) clamps the duct behind said band (24) to retain the duct on the component. The retainer strap detail is also disclosed.
Patent NZ-599524-A (NZ)
Title: Polysaccharide based hydrogels
Inventor: GONG GLEN
IPC: A61K9/14
Filed: 2010-11-05
Abstract: 599524 Disclosed herein are polysaccharide based hydrogel compositions and methods of making and using the same are provided. The subject polysaccharide based hydrogel compositions are prepared by combining a polysaccharide component with a hydrophilic polymer and a cross-linking agent. Also provided are kits and systems for use in preparing the subject compositions. Disclosed is a hydrogel composition comprising a polysaccharide substrate, such as chitosan, carboxymethylcellulose, carboxymethylchitosan, having a molecular weight of 160 Dalton to 80,300 Dalton and comprising at least two reactive nucleophilic groups; a synthetic, hydrophilic polymer, such as polyethylene glycol, with a molecular weight of 200 Dalton to 100,000 Dalton and comprising at least two nucleophilic reactive groups; and a crosslinking agent.
Patent NZ-601050-A (NZ)
Title: Beverage dispenser with safe cleaning arrangement with outlet duct moved to housing away from users to avoid steam or other cleaning fluids
Inventor: PERETTI LIONEL
IPC: A47J31/44
Filed: 2011-02-02
Abstract: 601050 A beverage preparation machine (1) has: a housing (5); a duct (10) with an outlet (15); a conduit (20) upstream the duct and connected thereto; and a waste liquid collector (30) arranged to collect waste liquid from the outlet. The duct has: an operative position for circulating beverage through the conduit and dispensing said beverage from the outlet outside the housing above a user-receptacle filling area (35); and a cleaning position for circulating cleaning fluid through the conduit and evacuating said cleaning fluid from the outlet inside the housing to the waste liquid collector. The duct is pivotally assembled about a pivoting axis (11) to the conduit for pivoting the outlet between the operative position and the cleaning position.
Patent NZ-603467-A (NZ)
Title: Supplementation of fatty acids for improving alcohol productivity
Inventor: BURLEW KEITH H
IPC: C07C29/86
Filed: 2011-06-17
Abstract: Disclosed is a method comprising: (a) providing biomass comprising a fermentable carbon source and oil; (b) converting at least a portion of the oil into fatty acids to form a biomass comprising the fatty acids; (c) contacting the biomass with a fermentation broth comprising a recombinant microorganism capable of producing a product alcohol from a fermentable carbon source, and wherein the recombinant microorganism comprises a reduction or elimination of pyruvate decarboxylase activity; (d) contacting the fatty acids with the fermentation broth, wherein at least one of (i) growth rate and (ii) fermentable carbon consumption of the recombinant microorganism is greater in the presence of the fatty acids than the growth rate and/or the fermentable carbon consumption of the recombinant microorganism is in the absence of the fatty acids.
Patent NZ-607560-A (NZ)
Title: Agricultural compositions comprising an oil-in-water emulsion based on oily globules coated with a lamellar liquid crystal coating
Inventor: TANK HOLGER
IPC: A01N25/04
Filed: 2006-07-28
Abstract: The disclosure relates to a composition comprising an oil-in- water emulsion, wherein the emulsion comprises oily globules which are each provided with a lamellar liquid crystal coating and are dispersed in an aqueous phase, wherein each oily globule comprises at least one agriculturally active compound selected from the group consisting of fungicides, insecticides, nematocides, miticides, biocides, termiticides, rodenticides, arthropodicides, and herbicides; and is individually coated with a monolamellar or oligolamellar layer comprising: (1) at least one non-ionic lipophilic surface-active agent that has Hydrophilic Lipophilic Balance (HLB) of between 2 and 5 and is selected from the group consisting of optionally ethoxylated mono- or polyalkyl ethers or esters of glycerol or polyglycerol, optionally ethoxylated mono- or polyalkyl ethers or esters of sorbitan, mono- or polyalkyl ethers or esters of pentaerythritol, mono- or polyalkyl ethers or esters of polyoxyethylene, and mono- or polyalkyl ethers or esters of sugars, (2) at least one non-ionic hydrophilic surface-active agent that has HLB of between 8 and 12 and is selected from the group consisting of mono- or polyalkyl ethers or esters of polyethoxylated sorbitan, mono- or polyalkyl ethers or esters of polyoxyethylene, mono- or polyalkyl ethers or esters of polyglycerol, block copolymers of polyoxyethylene with polyoxypropylene or polyoxybutylene, and mono- or polyalkyl ethers or esters of optionally ethoxylated sugars; and (3) at least one ionic surface-active agent that IS selected from the group consisting of (i) alkali metal salts of dicetyl phosphate and dimyristyl phosphate; (ii) alkali metal salts of cholesteryl sulphate and cholesteryl phosphate; (iii) lipoamino acids and their salts; (iv) phospholipids; (v) the mono- and disodium salts of acyl glutamic acids; and (vi) alkyl ether citrates, wherein the oily globules have a mean particle diameter of less than 800 nanometers.
Patent NZ-608253-A (NZ)
Title: New process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
Inventor: ALEXANDRE LE FLOHIC
IPC: C07C253/14
Filed: 2013-03-14
Abstract: Disclosed is a process for the synthesis of ivabradine of formula (I), characterised in that the compound of formula (VI) is subjected to a lactamisation reaction, in the presence of a coupling agent (such as oxalyl chloride, thionyl chloride, N,N-dicyclohexylcarbodiimide (DCC), 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDCI), N,N-carbonyldiimidazole (CDI), 1-propanephosphonic acid cyclic anhydride (T3P) and 1-(methylsulphonyl)-1Hbenzotriazole) and a base (such as triethylamine, diisopropylethylamine and pyridine), in an organic solvent (such as dichloromethane, tetrahydrofuran, acetonitrile, acetone and toluene), to yield ivabradine of formula (I), which may be converted into addition salts thereof with a pharmaceutically acceptable acid selected from hydrochloric acid, hydrobromic acid, sulphuric acid, phosphoric acid, acetic acid, trifluoroacetic acid, lactic acid, pyruvic acid, malonic acid, succinic acid, glutaric acid, fumaric acid, tartaric acid, maleic acid, citric acid, ascorbic acid, oxalic acid, methanesulphonic acid, benzenesulphonic acid and camphoric acid and into hydrates thereof. Also disclosed are synthetic intermediates selected from { 2-[2-({ 3[{ [(7S)-3,4-dimethoxybicyclo [4.2.0]octa-1,3,5-trien-7-yl]methyl} (methyl)-amino]propyl} amino)ethyl]-4,5-dimethoxyphenyl} acetic acid, { 2-[2-({ 3-[{ [(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl} (methyl)-amino]propyl} amino)ethyl]-4,5-dimethoxyphenyl} acetonitrile, (2-{ 2-[(3-chloropropyl)amino]ethyl} -4,5-dimethoxypheny)acetonitrile, Ethyl N-{ 2-[2-(cyanomethyl)-4,5-dimethoxyphenyl]ethyl} -ß-alaninate oxalate, (2-{ 2-[(3-hydroxypropyl)amino]ethyl} -4,5-dimethoxyphenyl)acetonitrile and 3-[{ [(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl} (methy)amino]-1-propanol.
Patent NZ-611571-A (NZ)
Title: Process for removing naphthenic acids from crude oil and crude oil distillates
Inventor: HARDACRE CHRISTOPHER
IPC: C10G21/28
Filed: 2011-11-23
Abstract: The disclosure relates to a process for removing organic acids from crude oil and/or a crude oil distillate containing organic acids. This is done by contacting the crude oil and/or crude oil distillate containing organic acids with a supported basic ionic liquid having a basic anion selected from hydrogencarbonate or alkylcarbonate, wherein the ionic liquid and the crude oil and/or crude oil distillate are in a mass ratio greater than 1:40, and obtaining a crude oil and/or crude oil distillate product having reduced acidity which is separated from the supported basic ionic liquid. The organic acids may be naphthenic acids.
Patent NZ-621776-A (NZ)
Title: Metal-coated steel strip
Inventor: SETARGEW NEGA
IPC: C23C2/34
Filed: 2012-10-18
Abstract: Disclosed is a method of forming an Al-Zn-Si-Mg alloy coating on a strip that includes dipping strip into a bath of molten Al-Zn-Si-Mg alloy and forming a coating of the alloy on the strip, with the Al-Zn-Si-Mg alloy containing in % by weight: Al: 2 to 19 %, Si: 0.1 to 2%, Mg: 1 to 10%, and Zn: 80 to 97 %, and with the bath having a molten metal layer and a top dross layer on the metal layer, and the method including providing calcium (Ca) in the composition of the bath to minimise the top dross layer in the molten bath.
Patent NZ-700629-A (NZ)
Title: Combination, kit and method of reducing intraocular pressure
Inventor: BAUMGARTNER RUDOLF A
IPC: A61P27/02
Filed: 2011-01-11
Abstract: The present disclosure is directed to a combination or a kit comprising a prostaglandin analog and an adenosine receptor A1 agonist of formula (I) and to a method of reducing intraocular pressure (IOP) in a subject using such combination or kit. The disclosire is particularly directed to a combination of latanoprost marketed under the brand Xalatan TM and Compound A.
Patent NZ-700869-A (NZ)
Title: Coated seed and methods for reducing seed dust
Inventor: REICHERT RONALD
IPC: A01P7/04
Filed: 2013-03-15
Abstract: Methods for reducing dust by treating a seed with a lubricant composition are described herein. The disclosure also provides for a method of reducing planter dust released during seed planting by applying a lubricant composition to a seed. Methods for increasing seed lubricity by coating a seed with a lubricant composition are also described. Compositions and seeds useful in these methods are also described.
Patent NZ-710334-A (NZ)
Title: A bed arrangement having zones with adjustable height/firmness
Inventor: STJERNA NILS ERIC
IPC: A47C27/06
Filed: 2014-01-14
Abstract: A bed arrangement comprising an upper mattress (2) and a support structure (41, 42, 43 and 43) arranged beneath the upper mattress (2) is disclosed. The support structure (41, 42, 43 and 44) comprises at least one flexible elongate element (42) that is arranged to extend between two holding elements (43, 44) arranged at opposite side of at least one variable zone in the bed arrangement. The upper mattress (2) is a pocket spring mattress and in that it further comprises a retraction device (45) arranged to control slack of the flexible elongate element(s) (42) by controlling the length of the flexible control element(s) (42) being provided between the holding elements (43, 44). Hereby, the height and/or firmness of the bed arrangement is controlled in the variable zone. The retraction device (42) is also arranged to retract the flexible elongate element(s) (42) by at least one of: rolling up the flexible elongate element(s) (42) around an axle; pulling an end of the flexible elongate element(s) (42); and pushing an end of the flexible elongate element(s) (42).
Patent NZ-711579-A (NZ)
Title: Processing biomass
Inventor: MEDOFF MARSHALL
IPC: C12P7/06
Filed: 2009-04-28
Abstract: Disclosed is a method for dissolving a lignocellulosic material, the method comprising combining a lignocellulosic material with a solvent system comprising DMSO and a magnesium salt. Further disclosed is a mixture comprising: (a) a low molecular weight sugar that is a carbohydrate or a derivative thereof having a formula weight, excluding moisture, that is less than 2,000, (b) a treated cellulosic or lignocellulosic material having a porosity of at least 35% and comprising a plurality of saccharide units arranged in a molecular chain, wherein from about 1 out of every 2 to about 1 out of every 250 saccharide units includes a carboxylic acid functional group, (c) an aqueous solvent, and (d) a fermenting microorganism, wherein the treated cellulosic or lignocellulosic material comprises a cellulosic or lignocellulosic material that has been irradiated with at least 5 Mrad of electron beam radiation, and the carboxylic acid functional groups act as receptor sites for the microorganism. Also disclosed is a fermentation method comprising: mixing in a medium a low molecular weight sugar, one or more fermenting microorganisms, and an ionizing radiation irradiated lignocellulosic material, fermenting the low molecular weight sugar to a fermentation product, wherein the fermentation step produces fermentation product at a faster rate than would be produced in the fermentation step in the absence of the irradiated lignocellulosic material.