baber/WOPTO huggingface dataset:
Patent NZ-236434-A (NZ)
Title: Dna molecules comprising the a niger pyruvate kinase transcription promoter, vectors containing it and their use in transforming host cells
Inventor: DE GRAAFF LEENDERT HENDRIK
IPC: C12N15/54
Filed: 1990-12-12
Abstract: The invention relates to the field of genetic engineering and provides novel DNA molecules comprising a fungal promoter. The novel DNA molecules are useful for the construction of hybrid vectors expressing genes in filamentous fungi. Objects of the invention are novel DNA molecules comprising the A. niger pki promoter, hybrid vectors useful for the expression of structural genes under the control of said promoter, hosts transformed with the novel hybrid vectors, and processes for the production of the novel DNA molecules, hybrid vectors, and transformed hosts and for the production of recombinant polypeptides by means of said transformed hosts.
Patent NZ-238303-A (NZ)
Title: Modified bacterium and its use to provide immunogens and vaccines against gram-negative bacteria
Inventor: LUBITZ WERNER
IPC: C07K16/02
Filed: 1991-05-29
Abstract: Modified bacteria, obtd. by (1) transforming a Gram negative bacterium with (a) the gene of a lytic membrane protein of a bacteriophage, (b) a lytic toxin-release gene or (c) their partial sequences which code for lytic proteins; (2) culturing the bacteria, (3) expressing the lytic genes and (4) isolation from the culture broth, are used as vaccines or adjuvants. - Pref. during culture, activation of the gene is inhibited or expression is repressed, and lifted only at selected times. The lytic gene is the DNA sequence for the E or L proteins (or their membrane-penetrating domains) or the EL-hybrid protein, or their active partial sequences.
Patent NZ-250871-A (NZ)
Title: Aqueous polymerisation of monomer mixture comprising at least 20 wt% monounsaturated acids using hypophosphorous acid as chain transfer agent
Inventor: FIARMAN IRWIN STANLEY
IPC: C08F2/38
Filed: 1994-02-14
Abstract: A process for using hypophosphorous acid or its salts as a chain transfer agent comprises polymerising one or more monomers, where at least 20 wt. % of the monomers are monoethylenically unsaturated acids or their salts, in the presence of: (a) water; (b) one or more water-soluble initiators; and (c) hypophosphorous acid or its salt; where 80-100 % of the monoethylenically unsaturated acids or their salts are metered into a polymerisation reactor contg. water, and 0-100% of the hypophosphorous acid or its salt, to provide a final polymer solids level of at least 50 wt.%.
Patent NZ-259361-A (NZ)
Title: Seco-6,8a-deoxy avermectin and milbemycin derivatives; antiparasitic compositions; s avermitilis strain atcc 55372
Inventor: HAFNER EDMUND WILLIAM
IPC: A23K20/195
Filed: 1993-12-16
Abstract: An antiparasitic compound of formula (I), (II) or (III) wherein R is selected from a variety of organic groups, the broken line represents an optional double bond, R<1> is H, OH, -O-alkyl or optionally substituted oximino, and R<2> and R<3> are H, OH, H, OMe, oxo, optionally substituted oximino or optionally substituted amino.
Patent NZ-302391-A (NZ)
Title: Optically active thiazolidinone derivatives having vessel dilating and an anti-angina pectoris action and use thereof as pharmaceuticals
Inventor: ISHIHARA SADAO
IPC: A61K31/426
Filed: 1996-03-01
Abstract: An optically active thiazolidinone derivative having the general formula: <CHEM> Äwherein R<1> represents a hydrogen atom, a C1-C4 alkyl group, a phenyl group, a substituted phenyl group (said substituent represents C1-C4 alkyl, C1-C4 alkoxy or halogen), a phenyl-C1-C2 alkyl group or a substituted phenyl-C1-C2 alkyl group (the substituent of said phenyl represents C1-C4 alkyl, C1-C4 alkoxy or halogen);     R<2> represents a C1-C6 alkyl group; and     n represents 1 or 2Ü. ÄEffectÜ   The optically active thiazolidinone derivative of the present invention has excellent anti-angina pectoris action and is useful as a preventive agent or a therapeutic agent for angina pectoris.
Patent NZ-314373-A (NZ)
Title: Preparation of calcium pyruvate or hydrates thereof using pyruvic acid and an inorganic calcium compound
Inventor: ZIMMERMANN CURT
IPC: C07C59/19
Filed: 1997-03-10
Abstract: Preparation of very pure calcium pyruvate (I) or its hydrate (IA) by reacting an aqueous solution of pyruvic acid (II) with an inorganic calcium compound (III) at pH 2-7, preferably 2.5-4. A 10% aqueous (II) solution is reacted with (III), optionally in the presence of a stabiliser or complex forming agent. The resultant solution is mixed with an organic diluent at 0-30 degrees C. The resultant precipitate of (I) or (IA) is isolated from the solution.
Patent NZ-334257-A (NZ)
Title: Spirocyclic metalloprotease inhibitors
Inventor: WANG ZHE
IPC: A61K31/435
Filed: 1997-08-22
Abstract: A metalloprotease inhibiting compound having a structure according to Formula (I) wherein:  Ar is alkyl, heteroalkyl, aryl or heteroaryl, substituted or unsubstituted  R1 is H;  R2 is hydrogen, alkyl or acyl;  W is nil or one or more alkyl moieties, or is an alkylene, arylene or heteroarylene bridge between two adjacent or nonadjacent carbons (thus forming a fused ring);  Y is independently one or more of hydrogen, hydroxy, SR3, SOR4, SO2R8, alkoxy, NR6R7;  R3 is hydrogen, alkyl, aryl, heteroaryl;  R4 is alkyl, aryl, heteroaryl;  R6 and R7 are independently chosen from hydrogen, alkyl, heteroalkyl, heteroaryl, aryl, OR3, SO2R9, COR9, CSR10, PO(R11)2; and  R8 is alkyl, aryl, heteroaryl, heteroalkyl, amino, alkylamino, dialkylamino, arylamino, diarylamino and alkylarylamino;  R9 is hydrogen, alkoxy, aryloxy, heteroaryloxy, alkyl, aryl, heteroaryl, heteroalkyl, amino alkylamino, dialkylamino, arylamino and alkylarylamino;  R10 is alkyl, aryl, heteroaryl, heteroalkyl, amino, alkylamino, dialkylamino, arylamino, diarylamino and alkylarylamino;  R1 1 is alkyl, aryl, heteroaryl, heteroalkyl;  Z is a spiro moiety;  n is 1-3.
Patent NZ-336847-A (NZ)
Title: Pharmaceutical delivery system consisting of u shaped member with delivery device having movement in a direction transverse to the plane of the arms, typically for ear, skin flap or tail of vertebrate animal
Inventor: HARLAND RICHARD
IPC: A61D7/00
Filed: 1998-01-20
Abstract: A pharmaceutical delivery system for use with a variety of delivery devices is disclosed. It is stated that the delivery system prevents, or reduces the incidence of, inappropriate administration of a drug or vaccine to the operator of the system. Methods of using the delivery system to administer a pharmaceutical to a vertebrate subject are also disclosed.
Patent NZ-337289-A (NZ)
Title: Composition comprising therapeutic agent, pectin and aqueous carrier for delivery of drugs to mucosal surfaces
Inventor: WATTS PETER JAMES
IPC: A61K9/00
Filed: 1998-04-20
Abstract: A single component product comprising a liquid pharmaceutical composition for administration to a mucosal surface is described. The composition comprises a therapeutic agent, a pectin with a degree of esterification of less than 50% and an aqueous carrier. The composition gels or can be adapted to gel at the site of application. Also described is the use of this composition in the manufacture of a medicament for use as a means of delivery of therapeutic agents to the nose, the vagina, the rectum, the back of the throat or the eye. A kit of parts which comprises the abovementioned composition is also described. The kit is packaged and presented with instructions to administer the composition to a mucosal surface in the absence of an extraneous source of divalent metal ions.
Patent NZ-337618-A (NZ)
Title: Enhanced effects of antipsychotic agents when combined with mirtazapine (anti-depressant)
Inventor: BROEKKAMP CHRISTOPHORUS LOUIS
IPC: A61P25/18
Filed: 1998-03-25
Abstract: Therapeutic combinations of mirtazapine and an antipsychotic agent, to pharmaceutical compositions containing said combinations and to their use in the treatment or prophylaxis of psychotic disorders.
Patent NZ-501679-A (NZ)
Title: Topical insect repellant made from ratite (rhea, emu, ostrich and cassowary) oil, active fractions thereof and one other insect repellant such as citronella or DEET
Inventor: MARRONE PAMELA GAIL
IPC: A01N63/10
Filed: 1998-05-07
Abstract: Compositions for repelling insects, particularly biting insects, such as mosquitoes, ticks, and biting flies comprising ratite oil, active fractions thereof obtained by flash chromatography and compositions comprising mixtures of fatty acids found in ratite oil are described. The compositions can further comprise at least one additional insect repellent such as citronella, N,N-dimethyl-m-toluamide (DEET), rotundial oil, eucalyptus oil, neem oil, oil of Hedeoma pulgloides, oil of anisum, oil of chrysanthemum, or saponin. Methods of repelling said insects are also provided.  A synergistic effect was also observed with diluted preparations of ratite oil and another insect repellent.
Patent NZ-502079-A (NZ)
Title: Method of prolonging crispyness (bowl life) of a cereal product comprising coating the cereal with rice syrup
Inventor: TRECE THOMAS
IPC: A23L1/164
Filed: 1998-03-02
Abstract: A method of extending the bowl life of a cereal-based food product comprising coating the cereal-based food product with rice syrup.  The cereal-based food product can also be coated with one of more compositions selected form waxes, lipids, emulsifiers and proteins.
Patent NZ-506425-A (NZ)
Title: An  edge  modification  apparatus  specifically   for applying an edging tape to furniture components
Inventor: SUCH DUNCAN KARL
IPC: B27G11/00
Filed: 2000-08-18
Abstract: An  apparatus (1) which includes a flat bed  (2)  onto which an arbitrarily shaped planar object (3) is placed  and preferably  clamped or fixed. The orientation of the  planar object  is  not important as the apparatus (1)  includes  an adaptive   capability.  The  flat  bed  2)  is  capable   of accommodating  a  range of differently  sized  objects.  The operation  involves the movement of an edge  follower  which includes  at least one contact roller to be pressed  against the  edge  (4a, 4b). The apparatus can be used for  cutting, trimming,  sanding  and gluing, painting and  deposition  of edging.
Patent NZ-507278-A (NZ)
Title: Production of mycobacterial polypeptides by lactic acid bacteria
Inventor: JENSEN CARSTEN LOVSTRUP
IPC: C07K19/00
Filed: 1999-03-05
Abstract: A method of producing, in a recombinant lactic acid bacterium such as Lactococcus lactis, a bioreactive polypeptide derived from mycobacteria belonging to the M. tuberculosis complex Mycobacterium tuberculosis, Mycobacterium africanum and Mycobacterium bovis or any other mycobacterial species. The lactic acid bacterially produced polypeptide is in the form of monomer or polymers of one or more polypeptide and it is useful as a diagnostic agent in delayed type hypersensitivity (DTH) skin tests in animals and humans and in vaccines. A bioreactive ESAT-6 homodimer polypeptide is described.
Patent NZ-507926-A (NZ)
Title: Phthalazine derivatives phosphodiesterase 4 inhibitors
Inventor: NAPOLETANO MAURO
IPC: C07D237/30
Filed: 1999-07-13
Abstract: Described are compounds of formula (I); in which  ------ is a single or double bond; Z is NH, methylene, a (C2-C6)alkylene chain optionally branched and/or unsaturated and/or interrupted by a (C5-C7)cycloalkyl residue; A is phenyl or heterocycle optionally substituted by one or more of oxo, nitro, carboxy groups and halogen atoms, or a COR4 group wherein R4 is hydroxy, (C1-C6)-alkoxy, amino optionally substituted by one or two (C1-C6)alkyl group(s) or by hydroxy; R is a (C1-C6)alkyl or polyfluoro(C1-C6)alkyl group; R1 is absent when ------ is a double bond or, when ------ is a single bond, R1 is (a) hydrogen; (b) (C1-C6)alkyl optionally substituted by aryl, by heterocycle or by a COR5 group wherein R5 is hydroxy, (C1-C4)alkoxy or hydroxamino; (c) -COR6 wherein R6 is hydrogen, aryl, aryl-(C1-C6)alkyl, amino optionally alkylated or monohydroxylated, hydroxy, (C1-C4)alkoxy, carboxy, (C1-C4)alkoxycarbonyl, formula (1), or (C1-C4)alkyl optionally substituted by heterocycle; (d) (C1-C4)-alkylsulfonyl; R2 represents two hydrogen atoms or a group =O when ------ is a single bond, or, when ------ is a double bond, R2 is hydrogen, cyano, (C1-C4)alkoxycarbonyl, amido, optionally substituted aryl or heterocycle, (C1-C8)alkyl, (C2-C8)alkenyl or (C2-C8)alkynyl optionally branched and/or substituted by aryl or heterocycle; aryloxy, heterocyclyloxy, aryl-(C1-C4)alkoxy, heterocyclyl-(C1-C4) alkoxy, amino substituted by one or two (C1-C4)-alkyl group(s), arylamino, heterocyclylamino, aryl-(C1-C4)alkylamino, heterocyclyl-(C1-C4)-alkylamino; and R3 is hydrogen, or a (C1-C8)alkyl, (C2-C8)alkenyl or (C2-C8)alkynyl group optionally substituted by hydroxy, oxo, aryl or heterocycle, and optionally interrupted by one or more heteroatom(s) or heterogroup(s).
Patent NZ-508874-A (NZ)
Title: FSH and FSH variant formulations, products and methods of treating infertility.
Inventor: HOFFMANN JAMES ARTHUR
IPC: C07K14/59
Filed: 1999-07-15
Abstract: A pharmaceutically acceptable formulation comprising FSH or FSH variant, containing an alpha and beta subunit, and a preservative selected from the group consisting of phenol, m-cresol, p-cresol, o-cresol, chlororesol, benzyl alcohol, alkylparaben, benzalkonium chloride, benzethonium chloride, sodium dehydroacetate, thimerosal, and mixtures thereof in an aqueous diluent.
Patent NZ-510282-A (NZ)
Title: Irrigation sprinkler cover having stable base and upstanding protective wall or walls
Inventor: MCFADZEAN COLIN BRUCE
IPC: B05B15/06
Filed: 2001-03-01
Abstract: A sprinkler housing (1) having a base portion (2), a sprinkler mounting means, and a wall portion (3) extending upwardly of the base portion, that is configured and arranged to, in use, support and bias the housing to maintain a substantially upright use position both when the housing is stationary and also when the housing is being moved from one location to another, the sprinkler mounting means being adapted to, in use, mount a sprinkler (9) unit having a rotatable sprinkler head (5), and the wall portion being configured and arranged to, in use, substantially protect a said sprinkler unit mounted in the housing from damage, yet at the same time allow at least a portion of the sprinkler head to protrude above at least a part of the upper edge of the wall portion.
Patent NZ-529355-A (NZ)
Title: Antagonists of TWEAK and of TWEAK receptor and their use to treat immunological disorders
Inventor: RENNERT PAUL
IPC: C07K16/28
Filed: 2000-01-14
Abstract: Compositions and methods comprising reagents that bind to the protein TWEAK, and the use of TWEAK binding reagents to block the development of immunologic disorders is disclosed. Particularly disclosed is a use of TWEAK blocking antibody against the TWEAK ligand or receptor and a pharmaceutically acceptable carrier in the preparation of a pharmaceutical composition for blocking the development or treating or reducing the severity or effect of an immune disorder in an animal. Other embodiments describe reagents that bind to TWEAK receptor(s) to modify their activity, or modify the intracellular signaling of TWEAK receptor(s). (62) Divided out of 513283
Patent NZ-529415-A (NZ)
Title: A method of microwave treatment of wood
Inventor: TORGOVNIKOV GRIGORY
IPC: F26B9/06
Filed: 2002-05-28
Abstract: A method of microwave treatment of wood with a moisture content (based on dry weight) of at least 12% for rapid drying and stress relief which includes determining an area of the wood that is not to be treated, selectively subjecting a surface of the wood outside said determined area to microwave radiation at a frequency (f) in the range of from about 0.1 to about 24 GHz to provide a modified wood zone having increased permeability relative to the untreated wood, wherein said zone is located in an exterior shell of the wood and has wooden rays directed from the core of the wood to the irradiated surface.
Patent NZ-529879-A (NZ)
Title: Biologically active peptides such as YSL and their use in pharmaceuticals
Inventor: WONG WAI MING
IPC: C07K5/107
Filed: 2002-07-11
Abstract: Disclosed is a pharmaceutical composition comprising a substantially pure peptide consisting of the amino acid sequence YSL (SEQ ID NO:16). Also disclosed is the use of the peptide for the treatment of various diseases.
Patent NZ-530777-A (NZ)
Title: Process of producing mannitol and homopolysaccharides
Inventor: VAN GEEL-SCHUTTEN GERRITDINA H
IPC: C12R1/225
Filed: 2002-07-24
Abstract: Describes a process of producing mannitol and/or one or more homopolysaccharides, the process comprising the steps of: fermenting sucrose by a bacterium expressing mannitol-2-dehydrogenase activity and one or more sucrase activities; recovering the mannitol or homopolysaccharides or both from the medium
Patent NZ-531474-A (NZ)
Title: Pharmaceutical compositions comprising the HMG CoA reductase inhibitorHMG CoA reductase inhibitor (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid with a ferric oxide light protective coating
Inventor: CREEKMORE JOSEPH RICHARD
IPC: A61K33/30
Filed: 2000-08-04
Abstract: Described herein is a pharmaceutical composition comprising (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R, 5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically acceptable salt thereof as the active ingredient, the composition having a ferric oxide light protective coating. The composition may further comprise an inorganic salt in which the cation is multivalent.
Patent NZ-531552-A (NZ)
Title: A process for making rare earth metal oxide-coated microporous materials
Inventor: WOODHEAD JAMES L
IPC: B01J23/10
Filed: 2002-09-12
Abstract: Disclosed is a process for making a catalytic rare earth metal oxide-coated microporous particulate material having the rare earth metal oxide coated on outer surfaces of the microporous particulate material, the process comprising the steps of: (i) combining an amount of a colloidal dispersion of rare earth metal oxide hydrate with a compatible micoporous particulate material to form a slurry, the microporous material having an average pore size less than the particle size of the colloidal dispersion, to position thereby the colloidal dispersion on the outer surfaces of the microporous particulate material, and (ii) heat treating the slurry to fix the rare earth metal oxide to the outer surfaces of microporous particulate material. Also disclosed is a catalytic rare earth metal oxide-coated zeolite free-flowing bulk particulate, comprising: a zeolite particulate material, a rare earth metal oxide, the zeolite particulate material having an average pore size less than a particle size of the rare earth metal oxide, and greater than 20% by weight of the rare earth metal oxide coated on outer surfaces of the zeolite particulate material, based on the total equivalent rare earth metal oxide and zeolite content.
Patent NZ-533442-A (NZ)
Title: Method and apparatus for making a pre-padded food bag
Inventor: BOAL DILIP KUMAR
IPC: B31B41/00
Filed: 2004-06-10
Abstract: Manufacture of a bag for containing food with a pre-inserted absorbent pad and apparatus for performing the manufacturing are described. A continuous web of flattened tubular thermoplastic material 11 is perforated on its bottom layer and has slits formed in it by knife 141 for insertion of absorbent pads. Blower 153 opens the slits while pad inserter 154 inserts the fluid absorbing pads. Seals are formed in the material at predetermined lengths to form a continuous web of bags containing the absorbent pads.
Patent NZ-540165-A (NZ)
Title: Composition for enhancing physical performance comprising quercetin, ascorbic acid and niacin
Inventor: LINES THOMAS CHRISTIAN
IPC: A23L33/00
Filed: 2003-10-23
Abstract: Disclosed is the use of a composition comprising quercetin, vitamin B3, and vitamin C in the preparation of a therapeutic formulation for enhancing physical performance. Also disclosed is a composition comprising vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B12, vitamin C, caffeine, quercetin, epigallocatechin gallate, epicatechin, epicatechin gallate, epigallocatechin, and polypheron E.
Patent NZ-543096-A (NZ)
Title: 2,3,6-trisubstituted-4-pyrimidone derivatives
Inventor: WATANABE KAZUTOSHI
IPC: C07D409/14
Filed: 2004-03-26
Abstract: Disclosed is a pyrimidone derivative of formula (I), wherein Q represents CH or N, R represents optionally substituted C1-C12 alkyl and the remaining substituents are as defined in the specification. The compounds are useful in the treatment of diseases caused by abnormal activity of tau protein kinase 1 including Alzheimer's disease, ischemic cerebrovascular accidents, Down syndrome, cerebral bleeding due to cerebral amyloid angiopathy, progressive supranuclear palsy, subacute sclerosing panencephalitic parkinsonism, postencephalitic parkinsonism, pugilistic encephalitis, Guam parkinsonism-dementia complex, Lewy body disease, Pick's disease, corticobasal degeneration, frontotemporal dementia, vascular dementia, traumatic injuries, brain and spinal cord trauma, peripheral neuropathies, retinopathies, glaucoma, non-insulin dependent diabetes, obesity, manic depressive illness, schizophrenia, alopecia, breast cancer, non-small cell lung carcinoma, thyroid cancer, T or B-cell leukemia, and a virus-induced tumor.
Patent NZ-545669-A (NZ)
Title: Portable storage device and method of managing files in the portable storage device
Inventor: LEE BYUNG-RAE
IPC: G06F21/00
Filed: 2005-02-28
Abstract: A portable storage device is disclosed, comprising a control module and a storage module. The control module sorts digital rights management (DRM) data from received data and forms a file comprising the DRM data. The control module sets a restricted region in the storage module, allocates a file identifier mapped to the file in the restricted region, and stores the file in the restricted region. The DRM data comprises a rights object or authentication information. A method of managing a file in a portable storage device is also disclosed.
Patent NZ-546018-A (NZ)
Title: Wheel reconditioning station and method of use
Inventor: IRBY PATRICK A
IPC: B60K17/35
Filed: 2004-08-06
Abstract: The present disclosure provides a compact and portable wheel reconditioning station that enables a technician to rotate and index a wheel while a tire is mounted thereto and while the wheel remains mounted on a vehicle. The device allows a technician to quickly and easily rotate or reposition a wheel by depression of a foot pedal to leave his hands free to manipulate the various tools that are used during the reconditioning process.
Patent NZ-548935-A (NZ)
Title: Biocatalytic oxidation of LL-F28249-alpha
Inventor: COHEN DANIEL HOWARD
Filed: 2006-08-04
Abstract: Disclosed is a process for the preparation of 23-keto-LL-F28249-alpha (moxidectin) which comprises reacting LL-F25249-alpha with a biocatalyst that is capable of specifically oxidising the 23-hydroxy group of LL-F28249-alpha.
Patent NZ-551458-A (NZ)
Title: Form-fill-seal process with formed and severed pouches are secured into outer pouches
Inventor: TUCKER MARK RUPERT
IPC: B65B9/02
Filed: 2005-05-24
Abstract: A one stage process for the preparation reservoir patches comprises feeding webs to a first pair of sealing rollers and, thence, directly to a second pair of die-cutting rollers, and preferably directly into a packaging step, thereby avoiding most operator related error, and substantially increasing overall sterility and reproducibility.