baber/WOPTO huggingface dataset:
Patent EP-4198515-A1 (EP)
IPC: G01N33/80
Filed: 2021-12-14
Abstract: Refrigerated storage of red cell concentrates (RCC) for transfusion is associated with the accumulation of various alterations to the red blood cells (RBCs). Among these, a subpopulation of small RBCs defined as storage-induced microerythrocytes (SMEs) accumulates during storage. The SMEs subpopulation correlates with transfusion recovery. Quantification of this morphologically-altered RBC subpopulation using flow cytometry would be a valuable tool to evaluate RCC quality. In the present invention, RBC obtained at the beginning or at the end of storage from RCC stored in SAGM in blood bank conditions were treated with a carboxyfluorescein diacetate succinimidyl ester (CFDA-SE) staining protocol and were finally analysed by flow cytometry to assess the intensity of CFSE staining. The inventors observed the accumulation of a CFDA-SE high  subpopulation by flow cytometry that accounted for 0.8% and 36.3% at day 3 and 42 of storage, respectively. Images confirmed that the CFDA-SE high  subpopulation mostly contains SMEs. Thus SMEs can now be simply quantified using a common fluorescent dye and a standard flow cytometer.
Patent EP-4104617-A1 (EP)
Title: Random access in a wireless communication system
Inventor: WANG MIN
IPC: H04W74/08
Filed: 2021-02-12
Abstract: A wireless device chooses a selection method from among multiple selection methods (22-1, 22-2) for selecting an occasion in which to transmit a random access preamble (16). The selections methods may for example include a random selection method in which the wireless device randomly selects an occasion and include a last-in-time selection method in which the wireless device selects an occasion that occurs last in time. Regardless, the wireless device selects, according to the chosen selection method, an occasion in which to transmit a random access preamble (16). The wireless device then transmits a random access preamble in the selected occasion, e.g., after performing a listen-before-talk procedure.
Patent EP-4298745-A1 (EP)
Title: Procédé et appareil de détection d'informations de commande de liaison montante non fiables
Inventor: YEPEZ ELIANA
IPC: H04L1/00
Filed: 2021-02-26
Abstract: L'invention concerne un procédé de fonctionnement d'un noeud de réseau dans un réseau de communication qui comprend un dispositif de communication. Le procédé peut consister à recevoir des informations de commande de liaison montante, UCI, provenant du dispositif de communication. Le procédé peut en outre consister à déterminer si les UCI sont fiables sur la base d'une distance maximale et d'une valeur seuil.
Patent EP-4103278-A1 (EP)
Inventor: BANERJEE MONALI
IPC: C07D239/80
Filed: 2021-02-12
Abstract: The present invention relates to compounds of formula (I). The compounds maybe used to antagonise the Stimulator of Interferon Genes (STING) protein and may thereby treat liver fibrosis, fatty liver disease, non-alcoholic steatohepatitis (NASH), pulmonary fibrosis, lupus, sepsis, rheumatoid arthritis (RA), type I diabetes, STING- associated vasculopathy with onset in infancy (SAVI), Aicardi-Goutieres syndrome (AGS), familial chilblain lupus (FCL), systemic lupus erythematosus (SLE), retinal vasculopathy, neuroinflammation, systemic inflammatory response syndrome, pancreatitis, cardiovascular disease, renal fibrosis, stroke and age-related macular degeneration (AMD).
Patent EP-4096681-A1 (EP)
Inventor: KAHVEJIAN AVAK
IPC: A61K31/7105
Filed: 2021-01-29
Abstract: This invention relates generally to delivery of circular polyribonucleotides and compositions thereof.
Patent EP-4118178-A1 (EP)
Inventor: VERAITCH FARLAN
IPC: C12M1/34
Filed: 2021-03-09
Abstract: The present invention provides a bioreactor (100) for cell processing. The bioreactor (100) comprises a container (110) having a base section (102) comprising a transparent or translucent sensor window (103), a top section (101) arranged opposite to the base section (102) and comprising a fluid inlet and a fluid outlet, and a sidewall (105) extending between the base section (102) and the top section (101) and defining an internal volume of the container adapted to hold a cell suspension. At least one optical element (106, 107) disposed on the sensor window (103) within the internal volume, the optical element (106, 107) being adapted to emit a fluorescence signal in response to incident light, the fluorescence signal being associated with one or more parameters of the cell suspension.
Patent EP-4085062-A1 (EP)
Inventor: PATHI SRINIVAS LAXMINARAYAN
IPC: A61P31/12
Filed: 2021-02-20
Abstract: The present invention relates to novel salts and/or co-crystals of tenofovir alafenamide with an acid selected from D-malic acid and adipic acid. Another aspect of the present invention relates to novel crystalline forms of the novel salts and/or co-crystals tenofovir alafenamide, process for preparation, the pharmaceutical formulations and therapeutic uses thereof for the treatment of diseases or symptoms of HIV infection and viral hepatitis B.
Patent EP-4132891-A1 (EP)
Title: Article optique à fonction antibactérienne
Inventor: MAURY HÉLÈNE
IPC: C03C17/42
Filed: 2021-04-09
Abstract: L'invention concerne un article optique, tel qu'une lentille ophtalmique, comprenant un substrat transparent présentant une face principale avant et une face principale arrière, au moins l'une de ses faces principales étant revêtue d'un revêtement interférentiel multicouche, tel qu'un revêtement miroir ou un revêtement antireflet, qui est le revêtement supérieur de l'article, la couche la plus à l'extérieur du revêtement supérieur comprenant un matériau présentant des propriétés antibactériennes, ou la couche la plus à l'extérieur du revêtement supérieur étant une couche poreuse et la couche directement sous la couche la plus à l'extérieur du revêtement supérieur étant une couche comprenant un matériau présentant des propriétés antibactériennes.
Patent EP-4143969-A1 (EP)
Title: Handgeführte werkzeugmaschine
Inventor: KOSCHEL CHRISTIAN
IPC: H03K17/955
Filed: 2021-04-20
Abstract: Die Erfindung betrifft ein Verfahren zum Betreiben einer handgeführten Werkzeugmaschine (1) mit einer Antriebseinrichtung (4), wobei eine Steuerungseinrichtung (8) zur Betätigung der Antriebseinrichtung (4) und wenigstens zwei mit der Steuerungseinrichtung (8) wirkverbundene, kapazitive Sensorelemente (30, 31, 32, 33) vorgesehen sind. Das Verfahren ist durch die folgenden Verfahrensschritte gekennzeichnet: - Ermittlung einer ersten und zweiten elektrischen Ladung des ersten und zweiten Sensorelements (30, 31, 32, 33), - Vergleichen der ermittelten ersten elektrischen Ladung mit einem definierten ersten Schwellwert und der ermittelten zweiten elektrischen Ladung mit einem definierten zweiten Schwellwert, der sich von dem ersten Schwellwert unterscheidet; - Freigabe der Betätigung der Antriebseinrichtung (4) durch die Steuerungseinrichtung (8), wenn die erste elektrische Ladung größer als der definierte erste Schwellwert und/oder die zweite elektrische Ladung größer als der definierte zweite Schwellwert ist. Es wird weiterhin eine Werkzeugmaschine (1) zur Durchführung eines derartigen Verfahrens beschrieben.
Patent EP-4193158-A1 (EP)
Title: Determining states of electrical equipment using variations in diagnostic parameter prediction error
Inventor: CHEIM LUIZ
IPC: G01R31/62
Filed: 2021-04-09
Abstract: Embodiments are disclosed for determining states of electrical equipment using diagnostic parameter prediction error. A prediction error value is determined for a plurality of predicted diagnostic parameter values over a predetermined time period for at least one component of an electrical equipment. The prediction error value suppresses variations observed in behavior of the at least one component. The determined prediction error value is compared to an expected prediction error value. An indication of a state of the at least one component is selectively generated based on the comparison.
Patent EP-4125725-A1 (EP)
Inventor: ANDERSON MARC A
IPC: A61F2/24
Filed: 2021-03-23
Abstract: Aspects of the present disclosure provide a delivery device including a tubular outer jacket having a distal end and a tyne assembly including a shaft supporting at least one tyne. In some aspects, an inner jacket is positioned within the outer jacket, wherein the tyne assembly is positioned between the outer jacket and the inner jacket. The delivery device has a delivery configuration in which the tynes are maintained within the outer jacket and a deployed configuration in which the tynes extend from a distal end of the tubular outer jacket. Aspects of the disclosure also provide methods of conducting a percutaneous coronary intervention including utilizing one or more tyne assemblies to engage the tynes of each tyne assembly with the frame to maintain the position of the delivery device.
Patent EP-4153898-A1 (EP)
Inventor: BERNHARDT JEAN-MARC
IPC: F17C3/00
Filed: 2021-05-03
Abstract: Tank for storing liquefied gas, in particular liquefied hydrogen, comprising a housing (2) defining a storage space extending in a main direction (A) which is horizontal in the usage configuration of the tank (1), the tank (1) comprising at least one deflecting wall (3) in the storage space, characterised in that it comprises several deflecting walls (3) in the storage space which extend with an offset in the main direction (A) to force the fluid to make at least one return trip in the longitudinal direction (A) while passing through the lower end and the upper end of the storage space (2).
Patent EP-4153680-A1 (EP)
Inventor: PUPOVAC KRISTINA
IPC: C08L69/00
Filed: 2021-05-11
Abstract: The present invention relates to a moulding compound containing: A) at least one polymer selected from the group consisting of polycarbonate and polyester carbonate; B) a polymer containing B1) at least one rubber-modified vinyl(co)polymer containing B1.1) 80 to 95 wt.%, based on B.1, of at least one vinyl monomer and B1.2) 5 to 20 wt.%, based on B1, of one or more rubber-elastic polybutadiene-containing graft foundations, wherein B1 contains polybutadiene-containing rubber particles, which are grafted with the vinyl monomers B1.1 and contain inclusions of vinyl(co)polymer consisting of the vinyl monomers B1.1, and a vinyl(co)polymer matrix which consists of the vinyl monomers B1.1 and is not bonded to these rubber particles and not enclosed in rubber particles, and optionally B2) further rubber particles, grafted with vinyl monomers, from B2.1) 5 to 75 wt.%, based on B.2, of at least one vinyl monomer grafted onto B2.2) 25 to 95 wt.%, based on B2, of one or more rubber-elastic graft foundations, wherein the weight ratio of the components B1 to B2 is at least 5:1; C) a master batch, which is solid at room temperature, containing C1) one or more copolymers containing structural units derived from an olefin and structural units derived from a polar comonomer, C2) a vulcanised silicone elastomer. The invention also relates to a method for preparing the moulding compound, to the use of the moulding compound for producing moulded bodies, and to the moulded bodies themselves.
Patent EP-4153529-A1 (EP)
Title: Valve for a beverage container
Inventor: LUTH HENDERIKUS HILVERT
IPC: B67D1/08
Filed: 2021-05-19
Abstract: Valve for a beverage container. A valve (1) for a beverage container (100) comprises a mounting element (10) for mounting the valve (1) in a container opening. The mounting element (10) extends radially from an inner side defining a fluid passage (12) through the mounting element (10) to an outer peripheral side for sealing against a container edge at the container opening. The mounting element (10) is coupled to a valve housing (20) comprising a housing side wall (21) extending axially from a housing top wall (22) to a housing bottom wall (23). The housing top wall (22) is sealed against the mounting element (10) and has a beverage outlet opening (25) aligned with the fluid passage (12). The housing side wall (21) has a beverage inlet opening. A valve body (30) is axially moveable inside the valve housing (20) from a first position closing off the beverage outlet opening (25) to a second position opening a fluid connection through the beverage outlet opening (25). The valve body (30) comprises a closed upper end section (31) fixedly received in the beverage outlet opening (25) in the first position and operable to be moved away from the beverage outlet opening (25) to the second position axially past at least a part of the beverage inlet opening in the side wall. The valve body (30) further comprises a lower end section (32) extending axially from the closed upper end (31) in the direction of the housing bottom wall (23), the lower end arranged to contact an inner surface of the housing (20) at least in the second position.
Patent EP-4146102-A1 (EP)
Title: Systèmes et procédés de commande de résection de tissu
Inventor: BOATENG KELVIN
IPC: A61B18/14
Filed: 2021-06-04
Abstract: Un procédé d'élimination de tissu peut consister à disposer un dispositif de résection de tissu au niveau d'un site tissulaire cible, amener le dispositif de résection de tissu à effectuer une résection d'un noyau de tissu à partir du site de tissu cible, retirer le noyau de tissu du corps, le retrait du noyau de tissu du corps créant une cavité de noyau au niveau du site de tissu cible.
Patent EP-4161244-A1 (EP)
Title: Guidance for an outdoor robotic work tool to an outdoor robotic work tool interaction station
Inventor: KAMFORS MATTIAS
IPC: A01D34/00
Filed: 2021-06-04
Abstract: The present disclosure relates to an outdoor robotic work tool interaction station (200) having a longitudinal extension (E) along which the interaction station (200) is adapted to receive an oncoming outdoor robotic work tool (100), and a vertical extension (V) that is perpendicular to the longitudinal extension (E). The interaction station (200) further comprises at least one radar reflective target (211, 212, 213).
Patent EP-4087418-A1 (EP)
Title: Dispositif de chauffage pour dispositif de vaporisation avec élément de préchauffage d'air et son procédé de production
Inventor: FUISZ JOSEPH M
IPC: A24D3/18
Filed: 2021-01-08
Abstract: Un dispositif de chauffage pour un vaporisateur doté d'un élément de préchauffage d'air comprend un boîtier, un tunnel ayant une partie inférieure perforée qui est une chambre de chauffage cylindrique pour placer une cigarette, un élément chauffant de type résistif, un échangeur de chaleur comprenant des canaux d'air pour la circulation et le préchauffage de l'air par un dispositif de chauffage, une extrémité supérieure et une extrémité inférieure, un trou d'admission d'air créé dans l'extrémité supérieure. Des trous de sortie sont en communication avec les sorties des canaux d'air de l'échangeur de chaleur pour l'admission d'air préchauffé par le dispositif de chauffage dans le tunnel. Le boîtier se présente sous la forme d'une bande d'un matériau diélectrique à couche mince résistant à la chaleur, sur laquelle une couche mince de matériau résistif avec des contacts est appliquée sur l'extrémité d'un côté, formant l'élément chauffant, et, sur l'autre côté, des éléments d'espacement supérieur et inférieur sont fixés et inclinés vers le milieu, ainsi que la bordure, qui sont constitués d'un matériau flexible résistant à la chaleur. La bande susmentionnée dotée d'un élément chauffant situé sur son côté externe est roulée en un cylindre et forme un tunnel, et est en outre enroulée en plusieurs bobines en spirale interconnectées, et forme un boîtier en spirale avec les extrémités supérieure et inférieure de sorte que les éléments d'espacement supérieur et inférieur et la bordure situés à l'intérieur forment un échangeur de chaleur en spirale comprenant les parties supérieure et inférieure et les conduits d'air en spirale centraux pour la circulation en spirale et en labyrinthe et le préchauffage de l'air, et au niveau de la partie inférieure se trouve un trou d'entrée supplémentaire pour l'admission d'air.
Patent EP-4090413-A1 (EP)
Inventor: BASSI THIAGO G
IPC: A61M16/04
Filed: 2021-01-13
Abstract: A stimulation device may include a tube, where the tube defines a lumen therein and a gas outlet. The gas outlet may be configured to allow gas to pass from the lumen to an exterior of the tube. The stimulation device may also include one or more first electrodes associated with the tube, one or more second electrodes, and a nasal cavity interface proximal of the gas outlet and the one or more first electrodes.
Patent EP-4179641-A1 (EP)
Title: Acars report communication system
Inventor: BONNET GUILLAUME RÉMI
IPC: H04B7/185
Filed: 2021-06-25
Abstract: This architecture for collecting and transmitting an aircraft (1) flight data report comprising at least one data acquisition unit (2; 11) installed on board the aircraft, means for transmitting the data report (3; 10; 27; 31) installed on board the aircraft and a station (7) for collecting the data report on the ground, comprises means (16) for calculating and taking into account a cost index for optimising the choice of the best means for transmitting the data report (3; 10; 27; 31) and its content with respect to this cost index.
Patent EP-4095023-A1 (EP)
Inventor: KATANO WATARU
IPC: B62K11/00
Filed: 2021-01-20
Abstract: The present teaching provides an MT straddled vehicle that has more flexibility in arrangement of a canister and some other components in a region enclosed by a crankcase, a cylinder and an air-intake system when the MT straddled vehicle is viewed along the crankshaft axial direction. An MT straddled vehicle according to the present teaching includes an engine provided to a frame in such a manner that the cylinder is in an upright posture; a starter motor that is located at one end of a crankshaft and starts the engine, the starter motor additionally functioning as a generator that generates electricity when driven by the engine; and a canister that is located in such a manner that at least part of the canister is in a region enclosed by the crankcase, the cylinder and the air-intake system when viewed along a crankshaft axial direction and said part of the canister is on a centerline when the MT straddled vehicle is viewed downward from above, the centerline being a line passing through a center of the MT straddled vehicle with respect to a vehicle width direction and extending in a forward-backward direction.
Patent EP-4101470-A1 (EP)
Inventor: KIM CHUL GEUN
IPC: A61K47/54
Filed: 2021-01-21
Abstract: The present invention relates to an unsaturated fatty acid-conjugated CP2c-targeting peptide-based agent. In the present invention, it was confirmed that by linking an unsaturated fatty acid to ACP52C, which is a CP2c-targeting peptide lead substance exhibiting an effect as a general-purpose anticancer agent,  in vivo  stability was improved without affecting the anticancer effect. Further, cancer cell-specific anticancer efficacy was confirmed in various cancer cells and normal cells.
Patent EP-4179619-A1 (EP)
Inventor: EVANGELISTI PAOLO
IPC: H02P29/50
Filed: 2021-07-08
Abstract: Embodiments described here concern a method to control a direct current motor (50) powered by an alternating supply voltage (Vin), which provides to detect the instant of the zero-crossing of the supply voltage (Vin) and to selectively activate a switch device (11) to power the motor (50) by means of the positive half-waves (Vinl) of the supply voltage (Vin) in order to make it rotate in one sense, and by means of the negative half-waves (Vin2) in order to make it rotate in the opposite sense. The invention also concerns a control circuit (10) for the motor (50).
Patent EP-4196560-A1 (EP)
Title: Laundry detergent composition
Inventor: GREEN ANDREW DAVID
IPC: C11D1/90
Filed: 2021-07-26
Abstract: A concentrated laundry detergent composition premix comprising water, 40 to 70% wt. surfactant of which from 20 to 80% wt. is non- ionic surfactant, 1.3 to 3.0% wt. a fatty acid and having a pH of from 6 to 7.4. A method for forming a laundry detergent composition by diluting a premix as described in water such that the final concentration of fatty acid is from 0.4 to 1.5% wt. A container comprising a premix as described.
Patent EP-4104390-A1 (EP)
Title: Vehicle security system
Inventor: GREEN BRIAN
IPC: H04L12/40
Filed: 2021-01-29
Abstract: A security system for a vehicle network of a vehicle is provided. The vehicle network includes a gateway and domain controllers for specific areas of the vehicle. The security system may validate messages sent from the gateway. The security system may also utilize split decryption keys in order to decrypt messages in the vehicle network. The security system may also utilize asymmetrical encryption keys in order to secure data within the vehicle network.
Patent EP-4193405-A1 (EP)
Inventor: HELLMANN MARK
IPC: H01M8/04119
Filed: 2021-07-19
Abstract: Die Erfindung betrifft ein Verfahren zum Betreiben eines Brennstoffzellensystems, bei dem mindestens einer Brennstoffzelle (1) über einen Anodenpfad (2) Wasserstoff und über einen Kathodenpfad Sauerstoff zugeführt wird und bei dem aus der Brennstoffzelle (1) austretendes Anodenabgas über einen Rezirkulationspfad (3) rezirkuliert wird, wobei im Anodenabgas enthaltener Wasserdampf mittels eines Zeolithspeichers (4) adsorbiert wird. Erfindungsgemäß werden zur Regeneration des Zeolithspeichers (4) folgende Schritte: a) Trennen des Zeolithspeichers (4) vom Rezirkulationspfad (3) durch Schließen mindestens eines Absperrventils (5, 6) und/oder Schalten eines Wegeventils (7), b) Erwärmen des Zeolithspeichers (4) mittels einer elektrischen Heizeinrichtung (8), so dass zuvor adsorbiertes Wasser desorbiert wird, und c) Entfernen von desorbiertem Wasser aus dem System durch erneutes Schalten des Wegeventils (7) und/oder durch Öffnen mindestens eines Spülventils (9, 10). Die Erfindung betrifft ferner ein Brennstoffzellensystem, das zur Durchführung des Verfahrens geeignet ist.
Patent EP-4107363-A1 (EP)
Inventor: VAN KUILENBURG ROBERT
IPC: E21B33/068
Filed: 2021-02-19
Abstract: A seal element for an annular control device includes an elastomer seal sleeve having an annular opening therein and arranged to be radially compressed to contact an exterior of a pipe disposed within the elastomer seal element. The elastomer seal sleeve comprises at least one of a wear resistant material disposed on an interior surface of the annular opening and a lubricant channel on the interior surface.
Patent EP-4192849-A1 (EP)
Inventor: JAIS PHILIPPE
IPC: C12N9/10
Filed: 2021-08-03
Abstract: The present invention concerns a method for expressing a recombinant DNA molecule in a eukaryotic host cell, comprising the steps of: (a) expressing or introducing at least one chimeric protein, in said host cell, wherein said chimeric protein comprises: (i) at least one catalytic domain of a capping enzyme, in particular selected in the group consisting of cap-0 canonical capping enzymes, cap-0 non-canonical capping enzymes, cap-1 capping enzymes and cap-2 capping enzymes; and (ii) at least one catalytic domain of a DNA-dependent RNA polymerase, in particular a bacteriophage DNA-dependent RNA polymerase, (b) constitutively or transiently downregulating the phosphorylation level of subunit α of translation initiation factor eIF2 (eIF2α) in said host cell. The invention also concerns an isolated nucleic acid molecule or a set of nucleic acid molecules, comprising or consisting of (1) at least one nucleic acid sequence encoding a chimeric protein comprising at least one catalytic domain of a capping enzyme; and at least one catalytic domain of a DNA-dependent RNA polymerase; and (2) at least one nucleic acid sequence downregulating the phosphorylation level of eIF2α in a eukaryotic host cell or encoding a polypeptide downregulating said phosphorylation level; and (3) optionally, at least one nucleic acid sequence encoding a poly(A) polymerase, as well as vectors, kits and cells comprising said nucleic acid molecule or set, and different uses and applications thereof.