baber/WOPTO huggingface dataset:
Patent MD-1265-Z (MD)
Title: Method for diagnosis of Wiskott-Aldrich syndrome
Inventor: ANDRIEŞ Lucia
IPC: G01N33/50
Filed: 2017-12-27
Abstract: The invention relates to medicine, in particular to medical genetics and can be used for diagnosis of patients with Wiskott-Aldrich syndrome.According to the invention, the method consists in isolating DNA using the Salting-out method and then implementing the conformational polymorphism analysis of single-stranded DNA, and if changes in the spatial conformation of single-stranded DNA are detected in the electrophoregram analysis, the determination of the nucleotide sequence of the WAS gene is further performed to determine the presence of the mutation and thus the diagnosis of Wiskott-Aldrich syndrome is established.
Patent ES-495184-A0 (ES)
IPC: D06L3/12
Filed: 1980-09-19
Abstract: Granular built detergent compositions having good textile softening and cleaning properties comprise a nonionic surfactant, a cationic textile softening agent, a detergent builder and an optical brightener of the 4,4'bis (triazinylamino) stilbene 2,2' sulphonic acid type in a zwitterionic form having a low rate of solution in an aqueous medium of pH 9 at 25 DEG  C.
Patent ES-504166-A0 (ES)
IPC: C12P35/06
Filed: 1981-07-21
Abstract: Deacetylcephalosporin C is prepared by contacting cephalosporin C with an acetylesterase produced by a strain belonging to the genus Auresbasideum or a mutant thereof. Deacetylcephalosporin C is known as a valuable intermediate in syntheses of therapeutically-useful cephalosporin compounds.
Patent ES-525612-A0 (ES)
IPC: C07D499/00
Filed: 1983-09-14
Abstract: Preparation and use of 6,alpha-methoxy-6,beta-2-(2-methylphenoxycarbonyl)-2-(thien-3-yl) acetamido penicillanic acid of the formula 
<CHEM>
 or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof. 
<??>Intermediate of formula (X) 
<CHEM>
 and pharmaceutical composition comprising a penicillin of the first-mentioned formula, optionally with a clavulanic-acid derivative.
Patent ES-543579-A0 (ES)
IPC: C01F11/18
Filed: 1985-05-10
Abstract: An agent for increasing the pH value of dental plaque, which contains at least one highly disperse, poorly soluble oxide, hydroxide or pure salt of one or more alkaline earth metal elements and a weak acid, having a specific surface area greater than 6 m2/g and a concentration of lattice defects which corresponds to a half width of the X-ray peaks for Cu-K alpha  radiation at glancing angles from 20 DEG  to 23 DEG  of more than 0.25 degrees, and a process for its preparation.
Patent FI-831639-A0 (FI)
Inventor: DEHLEN BENGT LARS ARNE
IPC: B07B1/49
Filed: 1983-05-11
Abstract: The screening system comprises a screen frame (7) with supporting elements (9) for a screen deck (1) fastened in the frame. The screen deck comprises several elongated screen elements placed adjacent each other. Included in the screen elements are stiffening elements. The stiffening elements are prestressed against the supporting elements by elastic deformation upon mounting in the frame. They can be plastically deformed in a direction opposite to this elastic deformation. The spring-back force resultant of the elastic deformation can be at least as large as an inertia resultant acting on the screen deck in the opposite direction, when the screen deck is used in a dynamic screening machine.
Patent FI-844929-A0 (FI)
Inventor: LERCH ULRICH
IPC: C07D209/52
Filed: 1984-12-13
Abstract: The invention relates to a process for resolving racemic mixtures of bicyclic imino- alpha -carboxylic acid esters into the components of the formula Ia and Ib   <IMAGE>   in which R1 stands for an aliphatic, cycloaliphatic, aromatic or araliphatic radical, A denotes hydrogen and B and C together form a carbon chain or C denotes hydrogen and A and B together form a carbon chain, by crystallizing diastereoisomeric salts, which comprises preparing the salts of the racemic esters with optically active O,O-diacyltartaric acids in a suitable solvent in which only one of the two diastereoisomeric salts crystallizes in optically pure form, if desired purifying the diastereoisomeric salt by recrystallization, reprecipitation or trituration, and finally adding basec to the salt to cleave it into the pure enantiomer of the formula Ia or Ib. The invention also relates to diastereoisomeric salts of an ester of the formula Ia or Ib and a diacyltartaric acid.
Patent FI-872065-A0 (FI)
Inventor: WILKINSON PETER
IPC: C25D3/48
Filed: 1987-05-11
Abstract: An acid gold electroplating bath contains gold in an electrodepositable form, (e.g. potassium gold cyanide), together with 3-(3-pyridyl) acrylic acid or 3-(3-quinolyl) acrylic acid, and optionally a metallic additive. The metallic additive is preferably a cobalt, nickel or iron salt.
Patent FI-872578-A0 (FI)
Inventor: MUELLER HANS
IPC: A61K38/00
Filed: 1987-06-09
Abstract: The process is characterised in that a solution of an immunoglobulin is heated in the presence of a carboxylic acid or of one of its salts and/or a saccharide under such conditions that pathogens which are capable of multiplication, in particular hepatitis viruses or HTLV III ("Aids") viruses, are inactivated. Such a preparation can be used for therapy or prophylaxis.
Patent FI-882432-A0 (FI)
Inventor: STRAESSLE MARCEL
IPC: F16B7/18
Filed: 1988-05-24
Abstract: A connecting element for a scaffolding framework rod has a bolt 141 rotatably mounted on one end of the rod, and a guide sleeve 151 with an axial through-bore into which a section of the bolt extends. The bolt is connected to a screw insert 161 guided by a pin 171 which rides in a slot 152 of the sleeve, and a spring 172 urges the guide sleeve against a sleeve insert 130, 121 mounted on the end of the rod.
Patent FI-884728-A0 (FI)
Inventor: HERT MARIUS
IPC: C09D123/00
Filed: 1988-10-13
Abstract: Polymers with a melt index of between 1 and 20 dg/min, containing units (A) derived from ethylene, units (B) derived from an anhydride of an ethylenically unsaturated  alpha , beta -dicarboxylic acid and, if appropriate, units (C) derived from an alkyl acrylate or methacrylate whose alkyl group contains from 1 to 12 carbon atoms, characterised in that, per 100 moles, they contain: from 83 to 99.7 moles of units (A), from 0.29 to 3 moles of units (B), from 0 to 13.6 moles of units (C) and additionally from 0.01 to 0.4 moles of units (D) derived from at least one polyol poly(meth)acrylate. The process for their preparation consists in copolymerising a mixture of ethylene, of anhydride of an ethylenically unsaturated alpha , beta -dicarboxylic acid, of at least one polyol poly(meth)acrylate and, if appropriate, of at least one alkyl (meth)acrylate, at a temperature of between 140 and 280 DEG C, at a pressure of between 1000 and 2500 bars, in the presence of at least one free-radical initiator, and is characterised in that, before the copolymerisation, the polyol poly(meth)acrylate is dissolved in a solvent.
Patent FI-895949-A0 (FI)
Inventor: WALDHAUER FRED DONALD
IPC: H03G9/18
Filed: 1989-12-13
Abstract: A programmable low voltage multi-band compression system suitable for use with hearing aids is described. Received audio signals are processed by a band split filter which separates the received audio signal into a plurality of frequency bands. A plurality of compressors coupled to the band split filter compresses each of the respective frequency bands. The output of the compressor are then summed to generate a composite audio signal. The compression ratio of each of the compressors is set, in response to a set of control signals, to a preselected independent value. The average gain of each of the compressors is set to a preselected level independently of the other compressors. In addition, the compression ratio of each compressor may vary with input signal level. Another set of control signals is employed for setting the gain of the compressor to provide a volume control function.
Patent FI-901097-A0 (FI)
Inventor: KRUSE DETLEV
IPC: E05B65/46
Filed: 1990-03-02
Abstract: The closing fitting for a drawer mounted slidably in a furniture body (10) is designed so that the drawer, when introduced over a short distance, is drawn into the closing position and is held in this position. The closing fitting is equipped with a rotatably mounted rotary slide (12) movable under the effect of a spring (14). When the drawer is being moved out, the rotary slide (12) is also moved by a switch projection (16) fastened to the drawer and at the same time is rotated over a part distance so far that the switch projection (16) comes out of engagement with the rotary slide (12) and the rotary slide is retained in the release position. When the drawer is being moved in, the switch projection (16) comes up against a stop projection (25) of the rotary slide, with the result that the rotary slide is moved back into the initial position under the spring effect in the opposite direction to the preceding movement, at the same time rotating in the opposite direction, and draws the drawer into the closing position. <IMAGE>
Patent FI-910816-A0 (FI)
Inventor: TSENG SHIN SHYONG
IPC: A61K31/395
Filed: 1991-02-20
Abstract: Compounds of formula <CHEM> wherein R1 is hydrogen, alkyl, carboxamidomethyl, 4-chlorophenyl, benzyl and (4-nitrophenyl)-methyl; R2 and R3 are hydrogen or alkyl, R4 is 3-pyridinyl or <CHEM> where R6 and R7 are hydrogen, halogen, alkyl, alkoxy, N-alkyl-N-acylamino, nitro, and trifluoromethyl and where halogen is selected from chlorine, fluorine, bromine and iodine; R5 is hydrogen or alkyl; and A-B is -C=C-R3- or <CHEM> which are useful antihypertensive and anxiolytic agents. c
Patent FI-913926-A0 (FI)
Inventor: ADAIR JOHN ROBERT
IPC: A61K/
Filed: 1991-08-20
Abstract: CDR grafted antibody is claimed having one chain derived from a first (acceptor) antibody and (pref. 2) CDR(s) derived from a second (donor) antibody. Residue(s) pref. residue 35 in the CDR grafted chain has been altered so it corresp. to the equiv. residue in the antibody. The CDR chains are pref. derived from a human lgG chain. The heavy chain may be derived from the human NEW M or EU or pref. KOL chain. The light chain is pref. derived from the human REl light chain. The CDR grafted antibody has an affinity for the CD4 antigen of 10power5 - 10power12 M-1 pref. 10power8. Affinity is similar to that of OKT4A. CDR(s) may be derived from a mammalian (murine) antibody. Prodn. of the antibody is claimed by recombinant DNA technology.
Patent FI-921365-A0 (FI)
Inventor: GLEIM GUNTER
IPC: G11B7/09
Filed: 1992-03-27
Abstract: A light beam which scans the data on an optical recording support, generates an r.f. signal in the recording and/or playback device. As the r.f. signal is interrupted when the light beam leaves a data track, the detector circuit recognises from the r.f. signal level whether the beam is passing from one data track to the next. As the interruptions in the r.f. signal can also be caused by dirt, damage or errors on the recording support, it is impossible to be certain whether such an interruption has been caused by a track change or by dirt, damage or errors on the recording support. In order to recognise track changes reliably, the detector circuit does not generate a signal indicating a track change until the r.f. signal (HF) is below a first predetermined threshold (R1) and at the same time a track error signal (TE) is above a second predetermined threshold (R2). Detector circuit which recognises when a scanner leaves a mark or data track, e.g. in CD players, video record players, DRAW-disc players and magneto-optical recording and/or playback devices.
Patent FI-933238-A0 (FI)
Inventor: CLEMENT ROBERT MARC
IPC: B23K26/08
Filed: 1993-07-16
Abstract: A method and apparatus are described for marking a moving body of material (26). The method comprises the steps of directing at the moving body (26) a high energy density beam (46,58), concentrating the beam so as to produce an illuminated spot at a location on or within the moving body (26), and moving the spot in accordance with the resultant of two components of movement, the first being equal to the velocity of the moving body (26) and the second being relative to the moving body (26) so as to create a mark of a predetermined shape. In a preferred embodiment the apparatus includes at least one moveable galvanometer mirror (68,70) capable of moving the spot in accordance with the resultant of the two components. <IMAGE>
Patent FI-952481-A0 (FI)
Inventor: PALERMO MARK G
IPC: A61P25/26
Filed: 1995-05-22
Abstract: This application relates to compounds of the formula   <IMAGE>   wherein R1, X, Y and n are as defined in the specification; and pharmaceutically acceptable addition salts thereof and optical and geometric isomers or racemic mixtures thereof; which compounds are useful for the treatment of various memory dysfunctions characterized by a decreased cholinergic function such as Alzheimer's disease. Compounds of this invention also inhibit monoamine oxidase and hence are useful as antidepressants.
Patent AP-9100311-A0 (AP)
Title: The invention of matrixing stereo sound digital television circuit.
Inventor: NGOMA GOLIATH ALFAZEMA
Filed: 1991-08-05
Abstract: Data matrixing was
Patent IL-63384-A0 (IL)
Title: Process for the purification of nicotinamide
IPC: C07D213/82
Filed: 1981-07-22
Abstract: Crude nicotinamide is purified by a recrystallization and in this way freed especially from nicotinic acid and salts of nicotinic acid. As solvent there is used a 2-methylpropanol-1 containing water. The recrystallization takes place at a pH between about 7 and 10.
Patent IL-83668-A0 (IL)
Title: Transdermal therapeutic system,its use and process for the production thereof
IPC: A61L15/58
Filed: 1987-08-27
Abstract: A therapeutic system for administering active substances through the skin has a back layer facing the skin, at least one store of active substance, a dispensing means for the active substance linked to the store of the active substance, a controlling means for the supply of the active substance which controls the supply of the active substance by the system and an adhesive means for attaching the therapeutic system to the skin. The dispensing means and the controlling means form a storage matrix (12) with one or more separate, spatially-defined stores of active substance in which the concentration of the active substance is higher than in the storage matrix.
Patent IL-90495-A0 (IL)
Title: Process for the preparation of 4-chloro-3-alkoxy-but-2e-enoic acid alkyl esters
IPC: C07C67/00
Filed: 1989-06-01
Abstract: A process for the production of 4-chloro-3-alkoxy-but-2E-enoic acid alkyl esters starting from 4-chloroacetoacetic acid chloride by reaction with a dialkyl sulfite. The produced intermediate products are used as structural elements for, i.a., pharmaceutical agents.
Patent AU-PS081502-A0 (AU)
Title: Connector for drug delivery system
IPC: A61F11/00
Filed: 2002-02-28
Abstract: A cochlear implant electrode assembly device comprising an elongate electrode carrier member ( 10 ) that has a chamber or lumen ( 14 ) for receiving a bioactive fluid that is delivered therein, and a fluid transfer connector ( 50 ) that is in fluid communication with the chamber ( 14 ) and through which a bioactive fluid can move from a location external the carrier member, such as a reservoir ( 23 ), to the chamber ( 14 ).
Patent FI-20021011-A0 (FI)
Inventor: TUOMINEN KARI
IPC: E04B5/32
Filed: 2002-05-29
Abstract: A steel beam arranged to serve together with concrete as a bearing composite structure for various slab systems, the composite structure comprising a base plate (1) and two web parts (2, 3) arranged side by side at a distance from each other and joined at first ends by means of a horizontal top part (4). The base plate (1), web parts (2, 3) and horizontal top part (4) are arranged to form a space that can be filled with concrete. At least one web part (2, 3) is made of a plate part formed of two longitudinal parts (2a, 2b, 3a, 3b) of the beam that are at an angle to each other. The plate part is fastened to the base plate (1) and top part (4) in such a manner that the lower part (2a, 3a) of the web part (2, 3) is at an angle to the base plate (1) and the upper part (2b, 3b) is substantially perpendicular to the base plate (1).
Patent IL-107923-A0 (IL)
Title: Fused benzo compounds
IPC: C07D319/16
Filed: 1993-12-07
Abstract: Fused benzo compounds of formula I are provided, wherein A is a 2 to 6 membered hydrocarbon spacer group, B is a polar divalent group selected from a group (a); U is C, N or CH; X is a divalent 3-4 membered chain optionally comprising one or more heteroatoms; R1 is an aliphatic hydrocarbon group, arylalkyl or diphenylalkyl; R2 and R3 are hydrogen or alkyl or together form an ethylene or propylene bridge; R4, R5 and R6 are hydrogen or substituents; R7 and R8 are hydrogen or substituents including -COOR9 and -CONR10R11; are 5-HT1A receptor ligands useful in the treatment of CNS disorders. Pharmaceutical compositions comprising the compounds and their use for the manufacture of a pharmaceutical preparation are also provided.\!
Patent IL-111080-A0 (IL)
Title: Process for producing powders
IPC: A61K9/00
Filed: 1994-09-29
Abstract: A method and system for improving the flow properties of finely divided powders is provided. The method includes (a) agglomerating the powder by passing it through a screw feeder; and (b) spheronizing the agglomerates. The method preferably further includes (c) sizing the spheronized agglomerates. Spheronization is preferably accomplished by tumbling the agglomerates in a tilted rotating container.
Patent IL-111851-A0 (IL)
Title: Improved synthesis of bisindolylmaleimides
IPC: C07D498/18
Filed: 1994-12-02
Abstract: The present invention provides a novel synthesis of the compounds of Formula (I): <CHEM> The compounds are produced in high yield and without utilizing expensive chromatographic separations. The synthesis is particularly advantageous because it is stereoselective.
Patent IL-112285-A0 (IL)
Title: Endoparasiticidal compositions containing preziquantel and epsiprantel
IPC: A61K38/15
Filed: 1995-01-09
Abstract: Endoparasitic activity of cyclic depsipeptides (I) comprising amino acid and hydroxycarboxylic acid units and having 6-30 ring atoms is increased by praziquantel (II) and epsiprantel (III). An endoparasitic agent contg. (I) together with (II) and (III) is also claimed. Known cpds. (I) are disclosed in EP382173 (depsipeptide PF 1022), WO9319053, J. Antibiotics 45 (1992) pp. 1207-1255 and pp 1273-1277, Helv. Chimn. Acta 46 (1963) pp 927-935 and pp 1715-1720, ibid, 47 (1964) pp. 166-173, Tetrahedron Letters 2 (1971) pp. 159-162, Biochem. Biophys. Res. Commun. 57 (1974) pp. 554-561 and Zh. Obshch. Khim. 41-(10) (10972) pp. 2320-2334. (II) is known from GB1441554 and (II) is known from EP134984 and EP185012.
Patent IL-112612-A0 (IL)
Title: Chamber for hydrating contact lenses
IPC: G02C/
Filed: 1995-02-10
Abstract: Male and female members for contact lenses are disclosed. Either member is able to hold the contact lens as it moves from station to station during the hydration process. The female member fits together with the male member forming a chamber. Each of the members contains a line centrally located so that both surfaces of the contact lens are flushed during the hydration process, and drainage takes place radially on the outside of the mated male and female chamber members. These members may be produced on a frame with a plurality of members, usually eight to a frame, to allow ease of processing. Full automation is possible, and complete and positive lens control during any step of the process through the packaging step is achieved.
Patent IL-125434-A0 (IL)
Title: Composition and method for treatment of phosphated metal surfaces
IPC: C23C22/83
Filed: 1997-02-21
Abstract: A rinse solution for the treatment of conversion-coated metal substrates for improving the adhesion and corrosion resistance of siccative coatings, comprising an aqueous solution of a Group IVA metal ion, namely, zirconium, titanium, hafnium, and mixtures thereof, and a phenol polymer, with the pH of the total solution about 3.5 to 5.1. A method for treating such materials by applying the rinse solution to the substrate.
Patent IL-138414-A0 (IL)
Title: Apparatus and method for optically measuring an object surface contour
IPC: G01B11/25
Filed: 1999-03-12
Abstract: An optical metrology system and method for rapidly and accurately measuring an object surface contour. The optical metrology system measures cross-sections of an object substantially orthogonal to an axis of the object includes a first and second optical assemblies each arranged proximate to opposing sides of a desired section of the object to be measured. The optical assemblies each include at least one source of electromagnetic radiation such as a laser, each configured to project a linear beam on a proximate object surface. The optical assemblies also include a line scan camera fixed relative to the lasers and having a single column of detector elements substantially parallel with the object surface. The camera receives reflections from the object surface which are provided to a controller for processing. The system also includes a first adjustment device for adjusting a distance between the lasers of each assembly and the object. This causes the linear laser beams to intersect each other at a scanning region. The size and configuration of the scanning region is based upon the configuration of the object surface and is substantially aligned with the column of detector elements in the line scan camera. The system also includes a second adjustment apparatus for adjusting a relative position of the object and the optical assemblies along the axis of the object to scan additional sections of the object. Preferably, the line scan camera is a CCD camera and the detector elements are CCD sensing elements. The controller determines the cross-section dimensions of the object at the desired section of the object,
Patent IL-142699-A0 (IL)
Title: System and method for frequency up-conversion
IPC: H04B7/12
Filed: 1999-10-18
Abstract: A method and system is described wherein a signal with a lower frequency is up-converted to a higher frequency. In one embodiment, the higher frequency signal is used as a stable frequency and phase reference. In another embodiment, the invention is used as a transmitter. The upconversion is accomplished by controlling a switch with an oscillating signal, the frequency of the oscillating signal being selected as a sub-harmonic of the desired output frequency. When the invention is being used as a frequency or phase reference, the oscillating signal is not modulated, and controls a switch that is connected to a bias signal. When the invention is being used in the frequency modulation (FM) or phase modulation (PM) implementations, the oscillating signal is modulated by an information signal before it causes the switch to gate the bias signal. In the amplitude modulation implementation (AM), the oscillating signal is not modulated, but rather causes the switch to gate a reference signal that is substantially equal to or proportional to the information signal. In the FM and PM implementations, the signal that is output from the switch is modulated substantially the same as the modulated oscillating signal. In the AM implementation, the signal that is output from the switch has an amplitude that is a function of the information signal. In both embodiments, the output of the switch is filtered, and the desired harmonic is output.