baber/WOPTO huggingface dataset:
Patent CR-20160231-A (CR)
Title: Control de malezas herbicida sinérgico a partir de combinaciones de 2,4-d-colina y glufosinato
Inventor: MANN RICHARD K ;
IPC: A01N39/04
Filed: 2016-05-19
Abstract: Se proporcionan en la presente composiciones herbicidas que comprenden una mezcla que comprende (a) una sal de colina de ácido 2,4-diclorofenoxiacético (2,4-D-colina) y (b) una sal de ácido 2-amino-4-(hidroximetilfosfinil)butanoico (glufosinato). Las composiciones proporcionan un control de malezas sinérgico de la vegetación indeseable y mayor tolerancia de cultivos en soja, maíz o algodón tolerantes a 2,4-D y glufosinato. Las composiciones también proporcionan control sinérgico de malezas de la vegetación indeseable en áreas que incluyen, pero sin limitación, áreas no cultivables, de cultivos perennes, de cultivos frutales y cultivos de plantación.
Patent CR-20170562-A (CR)
Title: Anticuerpos anti-receptor de transferrina con afinidad diseñada.
Inventor: GEORGES GUY
IPC: C07K16/28
Filed: 2016-06-22
Abstract: En el presente documento se comunica un anticuerpo anti-receptor de transferrina que se une específicamente al receptor de transferrina humano y al receptor de transferrina de macaco, que comprende i) un dominio variable de cadena pesada humanizado derivado del dominio variable de cadena pesada de la SEQ ID NO: 01, y ii) un dominio variable de cadena ligera humanizado derivado del dominio variable de cadena ligera de la SEQ ID NO: 26, en donde el anticuerpo tiene una velocidad de disociación por el receptor de transferrina humano que es igual o menor que (es decir, como máximo) a la velocidad de disociación del anticuerpo anti-receptor de transferrina 128.1 por el receptor de transferrina de macaco, en donde las velocidades de disociación se determinan mediante resonancia de plasmón superficial, y en donde el anticuerpo anti-receptor de transferrina 128.1 tiene un dominio variable de cadena pesada de SEQ ID NO: 64 y un dominio variable de cadena ligera de SEQ ID NO: 65.
Patent CR-20190390-A (CR)
Title: Flexible torque cable for delivery of medical devices
Inventor: GALE CAYTLIN
IPC: A61M25/09
Filed: 2018-02-23
Abstract: The present application describes delivery cables (200) for delivering a medical device (201). In one example, a delivery cable includes a flexible inner core (202), a proximal outer coil (210), and a distal outer coil (208). The proximal outer coil has a first rigidity. The distal outer coil surrounds at least a portion of a distal section (204) of the flexible inner core and has a second rigidity less than the first rigidity, thereby reducing bias placed on the medical device by the delivery cable.
Patent CR-20210460-A (CR)
Title: Compounds useful in hiv therapy
Inventor: VELTHUISEN EMILE JOHANN
IPC: C07H19/173
Filed: 2020-03-04
Abstract: The invention relates to compounds of Formula (I), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.
Patent CR-20230366-A (CR)
Title: Half-life extending moieties and methods of using the same
Inventor: HEUER JOSEF GEORGE
IPC: C07K16/18
Filed: 2022-02-01
Abstract: , biotherapeutics or biologics). The disclosure further relates to fusions and conjugates that include one or more of the compounds acting as t½-extending moieties, as well as pharmaceutical compositions including the same and their use in treating various conditions, diseases or disorders.
Patent EC-SP003557-A (EC)
Title: Derivados de eritropoyetina
Inventor: BAILON PASCAL SEBASTIAN
IPC: C07K14/00
Filed: 2000-06-30
Abstract: La presente invención se refiere a conjugados de eritropoyetina con poli (etilen glicol) comprendiendo una glucoproteína eritropoyetina que presenta al menos un grupo amino libre y que presenta la actividad biológica in vivo que hace que las células de la médula ósea incrementen la producción de reticulositos y glóbulos rojos y que es selccionada delo grupo que consiste en eritropoyetina humana y análogos de la misma que tienen la secuencia de la eritropoyetina humana modificada mediante la dición de entre 1 y 6 sitios de glicosiliación o mediante una nueva disposición de al menos un sitio de glicosiliación; dicha glucoproteina estando covalentemente unida a "n" grupos de poli (etlenglicol) de la fórmula -CO-(CH2)x -(OCH2 CH2)m-OR con el carbonilo de cada grupo de poli (etilenglicol) formando un enlace amida con uno de dichos amino; en donde R es alquilo inferior; x es 2 ó 3; m se encuentra entre alrededor de 450 y alrededor de 900; n se encuentra entre 1 y 3; y n y m son elegidosde forma que el peso melecular del conjugado menos la glucoproteina eritropoyetina se encuentre entre 20 Kilodaltons y 100 kilodaltons.
Patent EC-SP077409-A (EC)
Title: Inhibidores de la c-fms cinasa
Inventor: ILLIG CARL
IPC: A61K31/4439
Filed: 2007-04-20
Abstract: La invención se dirige a compuestos de fórmula (I): en donde A, X, R2 y W se establecen en la especificación, así como solvatos, hidratos, tautómeros y sales farmacéuticamente aceptables de los mismos, que inhiben a las proteínas tirosina cinasas, especialmente a la c-fms cinasa; métodos para el tratamiento de enfermedades autoinmunes; y enfermedades con un componente inflamatorio; tratamiento de metástasis a partir de cáncer ovárico, cáncer uterino, cáncer de mama, cáncer de colon, cáncer de estómago, leucemia de célula pilosa y carcinoma de pulmón no de célula pequeña; y tratamiento del dolor, incluyendo dolor esquelético ocasionado por metástasis tumoral u osteoartritis, o dolor visceral, inflamatorio, y neurogénico; así como osteoporosis, enfermedad de Paget, y otras enfermedades en las cuales la reabsorción ósea media la morbidez incluyendo artritis, falla de la prótesis, sarcoma osteolítico, mieloma, y metástasis tumoral al hueso, también se proveen los compuestos de fórmula (I).
Patent EC-SP099069-A (EC)
Title: Fertilizante seco con formulación que contiene hormona de crecimiento y métodos para su uso y fabricación
Inventor: JOHNSON LOUIS B
IPC: A61K36/05
Filed: 2009-01-14
Abstract: Una formulación de hormona de crecimiento incluye un componente desactivador de enzimas y un conservante. La formulación se puede incorporar a un fertilizante seco para aplicar usando el fertilizante en sí o a un componente del fertilizante tal como una o más de las cargas que se utilizan comúnmente en los fertilizantes.
Patent EC-SP099688-A (EC)
Title: Moléculas y métodos para modular la pro-proteína
Inventor: MIKHAILOV DMITRI
IPC: C07K16/40
Filed: 2009-10-13
Abstract: En la presente se describen epítopos de la pro-proteína convertasa-subtilisina/quexina tipo 9 (PCSK9), composiciones que se enlazan con PCSK9 y con los epítopos de PCSK9, y métodos para utilizar las composiciones.
Patent EC-SP982715-A (EC)
Title: Derivados de pleuromutilina y su uso en terapia antimicrobiana
Inventor: HUNT ERIC
IPC: A61K9/06
Filed: 1998-10-28
Abstract: Derivados de pleuromutilina en los que el resto de éster glicólico en la posición 14 está sustituido con R2 (CH2)mX(CH2)nCH2COO; se usan en terapia antimicrobiana.
Patent FI-19992123-A (FI)
Inventor: RAJAMAEKI VEIKKO
IPC: A61M1/00
Filed: 1999-10-01
Abstract: The invention relates to a suction bag assembly for collection of liquid fluid, the assembly comprising a collection container (1) open at its one end, a cover (4) for closing the open end of the collection container (1), a flexible suction bag (3) which is adapted insertable into the collection container (1) so as to be attached to said cover (4), a connector (2) adapted to the collection container (1) and communicating via a flow channel with a vacuum source so as to provide a vacuum between the interior surface of the collection container (1) and the exterior surface of the suction bag (3), a patient tubing connector (5) serving to provide fluid communications from the source of fluids being sucked to the interior of the suction bag (3), a conduit (7) adapted to the cover (4) for transmitting the applied vacuum to the interior of the suction bag (3), and a filter (6) adapted to the end of the conduit (7) exiting into the interior of the suction bag (3), whereby the filter serves to prevent contaminants from entering the vacuum system.
Patent FI-20050382-A (FI)
Inventor: SAEMPI JOUKO
IPC: D06F58/20
Filed: 2005-04-14
Abstract: A heat pump operated drying chamber, which comprises a first chamber part (1) for goods to be dried, a second chamber part (2) for the heat pump equipment and a rotatable drum (8) placed in the first chamber part (1) and in an easy way installed into and removed from chamber part (1), as let down on rolls (13),(14) installed in the chamber part, and drying air is conducted into drying drum (8) through free opening (17) arranged in the drum end and out from drum through holes in the other drum end.
Patent FR-1601107-A (FR)
Title: Concrete production
IPC: B28C7/04
Filed: 1968-07-16
Granted: 1970-08-10
Abstract: Concrete is produced so that the compsn. of the mixture is determined by the humidity rate of the sand which equals at least that of a stored sand. Mixing of the ingredients includes the determination of the humidity of the sand to be used, providing water to supplement the actual content to that required whilst also weighing the sand and the water. Suitable equipemt is described.
Patent FR-1603135-A (FR)
Title: Reinforced rubber vehicle tracks prodn
IPC: B29D30/52
Filed: 1968-07-08
Granted: 1971-03-22
Abstract: Rubber belting incorporating reinforcement comprises a cable laid helically to form the neutral axis of the final belt, these longitudinal cables being pref. sandwiched by short cables laid transverse and enclosed by cross ply fabrics to control the stiffness of the structure. These core elements are pref. enclosed by (partially cured) rubber with the helical core cables suspended under tension between a pair of rolls with one run passing through a curing oven. Lay-up of the unvulcanised rubber components in tension (supported by the reinforcing cables) avoids localised stresses and contration experienced with slack lay-up, esp. in large belts such as vehicle tracks with a 15 m loop.
Patent GB-1050234-A (GB)
IPC: H01B3/20
Abstract: 1,050,234. Mineral oil compositions. ESSO RESEARCH & ENGINEERING CO. Oct. 9, 1964 [Oct.31, 1963], No. 41329/64. Heading C5E. A mineral oil composition comprises a major proportion of a mineral base oil and 0À1-10% of a heavy cycle gas oil fraction obtained in the catalytic cracking of a petroleum fraction, the base oil and gas oil having been subjected to treatment with hydrogen either separately or in admixture.
Patent GB-1051986-A (GB)
IPC: E04C2/26
Abstract: 1,051,986. Substituted stilbenes. HICKSON & WELCH Ltd. Feb. 1, 1965 [Feb. 13, 1964], No. 6125/64. Heading C2C. [Also in Division D1] The invention comprises compounds of the formula in which X represents the substituted anilino group Y.C 6 H 4 .NH- where Y is a sulphonic acid, carboxylic acid or sulphonamido group or such a group which is further substituted in the benzene ring by at least one chlorine atom or alkyl or alkoxy group containing 1-4 carbon atoms; and salts of such compounds and a process for the preparation thereof comprising the steps of (a) replacing one chlorine atom of cyanuric chloride by reaction with #-(#-hydroxyethoxy) ethylamine of the formula (b) replacing another chlorine atom of each of the cyanuric chloride by reaction with 4,4<SP>1</SP>- diaminostilbene-2,2<SP>1</SP>-disulphonic acid, and (c) replacing the third chlorine of the cyanuric chloride by reaction with a compound of the formula XH, the steps (a), (b) and (c) being carried out in any desired order and then, if desired, converting the compound of the first formula above thus formed to a salt thereof. Examples are furnished. The products are used as whitening agents in the treatment of textiles and paper-making.
Patent GB-1225609-A (GB)
IPC: B65G13/10
Filed: 1969-08-04
Abstract: 1,225,609. Roller conveyers. KARL STUMPF K.G. 4 Aug., 1969 [27 March, 1969], No. 38911/69. Heading B8. [Also in Division F2] A roller assembly for roller conveyer comprises a plurality of barrel-shaped rollers 3 rotatably supported on pins 4 carried by ribs 2 on a corrugated plate 1. A sleeve 5 connected to the plate 1 permits rotation of the roller assembly on a shaft. The corrugations are shaped in accordance with the shape and number of the rollers 3 and, with the ribs, form pockets in which the rollers 3 are housed. A plurality of the roller assemblies may be mounted on shafts.
Patent GB-1227076-A (GB)
IPC: C23G3/00
Filed: 1969-04-25
Abstract: 1,227,076. Descaling steel. MITSUBISHI JUKOGYO K.K. April 25, 1969 [April 26, 1968], No.21375/69. Heading C7E. Chromium-containing steel is descaled by wetting its surface with an aqueous solution of an alkali metal compound which is capable of reacting with the scale in the presence of oxygen to form a coating of an alkali metal compound that is soluble in acid or water, subjecting the coated steel to a temperature which is higher than the melting point of the applied alkali metal compound in the presence of an oxygen containing atmosphere, and then washing the steel surface. The alkali metal compound which is applied may be NaOH or KOH or a compound which hydrolyses to give one of these, e.g. Na 2 CO 3 , K 2 CO 3 , or Na or K silicate, and the solution of alkali metal compound, which is applied by dipping or spraying, may also contain an oxidizing agent such as Na NO 3 , KNO 3 , or NaClO 3 . The washing of the surface may be done with an inorganic acid such as HNO 3 , H 2 SO 4  or HF.
Patent GB-1227777-A (GB)
IPC: B60G/
Filed: 1968-05-30
Abstract: 1,227,777. Preventing lateral canting. INDUSTRIAL DEVELOPMENT CO. ETABS. 30 May, 1968 [19 June, 1967], No. 25910/68. Heading B7D. A vehicle suspension for a pair of front or rear wheels 1, 4 of a vehicle comprises a pair of aligned transverse torsion bars 23, 27 which are each connected, as by a link 26, 30, to a respective suspension arm 2, 5 and at their opposed ends act on electric or hydraulic distributers 19, 22 which permit free communication between the oil chambers 10, 16 of a pair of hydropneumatic suspension springs when there is no relative rotation between the distributers but on relative rotation of the distributers connect one oil chamber to a pressure fluid source and the other oil chamber to a fluid return circuit to correct trim on roll. The opposed faces 31, 32 of the distributers have corresponding ports 34, 42, connected to pressure inlet lines 54, 43, ports 35, 44 connected to the oil chambers 20, 21 and exhaust ports 36, 37, 41, 45. On relative rotation of the faces 31, 32 due to vehicle roll the ports 35, 44 and hence the oil chambers are connected respectively to the requisite inlet and exhaust ports to move the spring pistons 8, 14 to cancel the roll. Friction in the support bearings of the distributers effectively provides a time delay in their operation. In a modification (Fig. 5) the opposed distributer faces abut a fixed member 53 with a single feed line 54 and single exhaust line 55.
Patent GB-1230558-A (GB)
IPC: F16D55/14
Filed: 1969-01-23
Abstract: 1,230,558. Clutch-type disc brakes. GIRLING Ltd. 6 Jan., 1970 [23 Jan., 1969], No. 3802/69. Heading F2E. The invention relates to disc brakes of the kind in which relatively stationary and rotatable surfaces are brought into frictional engagement by axial separation of a pair of co-operating pressure plates between which are arranged angularly-spaced balls working in complementary inclined recesses in the plates, the application of the brake being initiated by moving the plates angularly in opposite directions by a pull-rod coupled by toggle links to lugs on the plates, or equivalent means. The rotatable surfaces may be formed by or on discs splined or otherwise keyed for axial sliding movement on a rotatable shaft, and the stationary surfaces by the end walls of a housing enclosing the discs and pressure plates. The pressure plates are centralized by angularlyspaced pilot lugs projecting inwardly from the housing, and after the initial angular movement of the pressure plates in opposite directions the plates are carried round with the rotating discs until a projecting lug on one plate engages an abutment face on a pilot lug which arrests its movement while the other plate continues to move angularly, whereby the plates are urged apart in an axial direction to apply the brake. In such a brake, at least one insert of a material having a low coefficient of friction is located in a position where there is normally frictional engagement between a pressure plate and the stationary housing of the brake. As shown in Fig. 1, a hole 12 drilled in a pilot lug 10 extending radially inwardly from a housing 11 receives a cylindrical insert or plug 13 of an alloy having a low coefficient of friction. The plug when seated projects a short distance from the inner face of the lug. A second insert can be provided in another lug, staggered axially with respect to the first, so that the brake may be applied whatever the direction of rotation of the brake discs. The plug may have a head (Fig. 2, not shown). A cylindrical insert 21, Fig. 4, may be received in a recess 22 in the periphery of a pressure plate 23. The insert may have a head (Fig. 3, not shown). The insert may be a cylinder 28 inserted sideways, Fig. 7, to project slightly beyond the periphery of pressure plate 31. The recess may be rectangular instead of part-circular (Fig. 5, not shown). One end of the insert may have a lug extending radially inwardly of the plate and accommodated in a recess in one face of the plate to prevent axial movement of the insert (Fig. 8, not shown).
Patent GB-1232692-A (GB)
IPC: H02K39/00
Filed: 1968-05-27
Abstract: 1,232,692. A.C. generators, E. HAYASAKA. 27 May, 1968 [29 May, 1967], No. 25197/68. Heading H2A. A homopolar A.C. generator applicable to tachometers comprises a rotary driven shaft 10 upon which is mounted with its magnetic axis coincident with the axis of the shaft a rotary magnetic pole body 11 having N and S poles adjacent one of which is mounted a partially cylindrical polepiece 12, and a stator having in a yoke 14 cores 15a, 15b wound with armature coils 17a, 17b and provided with partially cylindrical core pieces 16a, 16b of substantially the same axial length as the polepiece 12 from which they are spaced by air gaps c, the structure providing a magnetic flux path from one body pole N, through the polepiece 12, the air gaps c, the core pieces and cores 16a, 16b, 15a, 15b, and the yoke 14, to the other body pole S. The body 11 is either an electromagnet or a permanent magnet, e.g. of barium-ferrite or manganese-ferrite, and the polepiece 12 has a square, triangular or sinusoidal developed shape to produce a corresponding output waveform. In addition to the 1-ph. single pole, single element generator shown, the Specification discloses 3-ph., two pole, two element generators.
Patent GB-1232933-A (GB)
IPC: C03C3/102
Filed: 1969-03-04
Abstract: 1,232,933. Glass for ultrasonic delay line. CARL - ZEISS - STIFTUNG, [trading as JENAER GLASWERK SCHOTT & GEN.]. 4 March, 1969 [8 March, 1968], No. 11466/69. Heading C1M. [Also in Division H3] A glass for use as an ultrasonic delay line has the following composition in percentage by weight: SiO 2  50-63 B 2 O 3  0-5 K 2 O 5-15 BaO 10-25 ZnO 5-12 Al 2 O 3  0-3 Sb 2 O 3  0-2 WO 3  0-3 As 2 O 3  0-2, in which up to 18 of the BaO and ZnO content is replaceable by PbO, the respective minima of 10 BaO and 5 ZnO still applying, and up to 2 of the BaO is replaceable by TiO 2  and/or ZrO 2 . The glasses in question have a low internal attenuation, and transformation temperatures between 550 and 620 C.
Patent GB-1232997-A (GB)
IPC: H01Q21/12
Filed: 1967-08-25
Abstract: 1,232,997. Aerials. BRITISH BROADCASTING CORP. 9 Aug., 1968 [25 Aug., 1967], No. 39294/67. Heading H4A. An aerial array consists of a plurality of spaced-apart parallel dipoles which are formed by conductive patterns 13, 14 on the respective facing surfaces of two parallel insulating panels 10, 11 which are spaced apart by an air gap. The said patterns include vertical central and opposite feeder strips, from which horizontally disposed dipole arms extend. The feeder strip on the panel 10 is associated with R.H. dipole arms 18, 19 and L.H. dipole arms 17, 20 and the feeder strip on the panel 11 is associated with R.H. dipole arms 171, 20<SP>1</SP> and L.H. dipole arms 181, 19<SP>1</SP>. The two panels are identical, one being turned over so that the two patterns are facing. A coaxial line feeds to the centre of the aerial feeder strip line via a balun 25 and, with a vertical spacing between dipoles of half the mean wavelength, the dipoles are energized cophasally. The panels 10, 11 are glass fibre sheets and the patterns 13, 14 are of adhering copper foil, and may be formed by a printed circuit process. The dipole arms are of triangular shape, for wide-band operation. A reflecting screen 15 may be provided behind the panel 10. An omni-directional aerial system may comprise three or four arrays of the kind described, arranged in box formation around a vertical axis.
Patent GB-1238420-A (GB)
IPC: G04B27/00
Filed: 1969-09-19
Abstract: 1,238,420. Calendars and clocks. BRAUN A.G. Sept.19, 1969 [Sept.23, 1968], No.46216/69. Heading G3T. In a power driven digital calendar or clock having date or time indicating tablets a disengagable coupling is provided between the drive and the tablet moving mechanism. Hour and minute tablets 3, 4 of a digital clock are driven by a movement 8 via toothed wheels 81, 71, a coupling 7, a toothed wheel 72, an arbor 6, and reduction gearing 5. In the coupling 7 a pin 711 on the toothed wheel 71 engages a pin 721 on the toothed wheel 72 to drive the latter. The toothed wheel 71 is manually rotatable by a knob 9 so that if the clock is fast the knob 9 may be adjusted by reference to a scale 91 to displace the pins 711, 721 by a desired amount to stop the clock until the pins 711, 721 re-engage at the correct time. If the clock is slow the knob 9 is timed to move the tablets 3, 4 forwardly as desired.
Patent GB-1239683-A (GB)
IPC: B06B1/08
Filed: 1969-09-25
Abstract: 1,239,683. 683. Magnetostrictive transducer. STANDARD TELEPHONES & CABLES Ltd. Sept.25, 1969, No.47176/69. Heading G1N. [Also in Divisions H2 and H3-4] A magentostrictive transducer comprises a body of magnetostrictive material 2 in which is established closed loops of magnetic flux 4. A coil, 5, is arranged about the body, with its turns in a plane transverse the plane of the loops of flux a signal developed across the ends of the coil being associated with a magnetic flux 6, 7, within the body which interacts with the closed loops of flux. The interaction is the result of, or results in, bending of the body about a line perpendicular the plane of the closed loops of flux. The closed loops of flux may be produced by a remanent field in the body or by passing a current through the body from side to side in a direction perpendicular the plane of the flux loops. Alternatively if the element material is insulating the current may flow through a conductor passing through a hole in the element. Fig.3 shows a transducer with an element 2 having a coil 8 and means for passing a current through the width of the element. Either the coil, or the path through the element, may be provided with a D. C. biasing current while the other is used as the signal conductor to which a signal is applied to cause bending oscillations of the element, or from which a signal is derived due to bending applied to the element. The element may be used in a gramophone transducer, resonant filter or strain gauge.