baber/WOPTO huggingface dataset:
Patent DE-60319151-T2 (DE)
Inventor: NAHAR PRADIP
IPC: C12Q1/68
Filed: 2003-03-31
Granted: 2008-12-04
Abstract: This invention relates to a rapid and efficient method for carrying out enzyme-linked immunosorbent assay for detection of minute quantities of biomolecules such as antigen, antibody etc. This invention particularly relates to heat-mediated immobilization of antigen or antibody on to the activated surface followed by performing subsequent steps of ELISA by controlled temperature. The invented procedure has reduced the total time required for ELISA to around 3 h. The invented ELISA procedure is rapid, economical, reproducible and simple. The invented procedure is useful for carrying out ELISA required in clinical diagnostics, molecular biology, agriculture, food technology, environmental science, etc. The invented ELISA method is simple, time saving and obviates the time consuming procedure. This method has the potential for automation.
Patent DE-60319792-T2 (DE)
Inventor: BARBANTI GIOVANNI
IPC: B60C23/06
Filed: 2003-07-28
Granted: 2009-04-23
Abstract: A device for surveying the radial deformation state of a tire comprises a sensor of the difference between the pressure of the gas inside the tire and the atmospheric pressure; an optical device for outside signalling operating when this difference in pressure decreases under a pre-established threshold value (Fig. 1). <IMAGE>
Patent DE-60320622-T2 (DE)
Inventor: RANI ROBERT G
IPC: A61J1/05
Filed: 2003-10-10
Granted: 2009-06-10
Abstract: The sterile closure device (20) includes a cylinder which extends through a base (22) and a support (26). The cylinder has openings which are blocked by seals. A portion of the cylinder between the seals defines a chamber. An independent claim is also included for a container for a medical fluid.
Patent DE-68903673-T2 (DE)
Inventor: LOELIGER JUERG
IPC: A23L27/10
Filed: 1989-04-13
Granted: 1996-02-01
Abstract: To protect a dry food against oxidation, vanillin is added to it in a quantity of 5 to 5000  mu g vanillin per g food dry matter.
Patent DE-68906664-T2 (DE)
Inventor: PALUMBO GIANFRANCO
IPC: A61F13/15
Filed: 1989-11-21
Granted: 1993-09-16
Abstract: An absorbent element for absorbent articles comprised of hydrophilic fibres (24) and a discontinuous, non-uniform layer of particles of absorbent hydrogelling material (17) arranged on the upper surface of the element includes a deposition zone on which the absorbent hydrogelling material is distributed with an increased surface density. The zone of increased surface density of the absorbent hydrogelling material can preferably be located in different positions suitable for the different anatomical forms of the users, so as to ensure more effective sealing against the backflow of the liquid and thus ensure an improved feeling of dryness.
Patent DE-68908342-T2 (DE)
Inventor: BEUN NICOLAAS HERMAN
IPC: A61N1/08
Filed: 1989-10-25
Granted: 1994-02-24
Abstract: Electrotherapy apparatus which is capable of generating direct currents or alternating currents to be applied to a patient via electrodes (39, 40). The apparatus comprises two controllable voltage/current converters (1, 2), the current input of each of these converters being connected via a resistor (5, 6) to a first supply voltage terminal and the control voltage input being connected to a waveform generator (16). The apparatus comprises furthermore a transformer of which the secondary winding (7) is connected via at least one relay contact (8, 9) to the electrode output circuit. The two ends of the primary winding (3) are each connected to a current output (1b, 2b) of one of the said converters (1, 2) and a centre tapping of the primary winding (3) is connected to the second supply voltage terminal. A protective circuit is connected to the two resistors (5, 6) which monitors the current through said resistors during operation and which, if a predetermined parameter of said current is exceeded, operates a relay (10), as a result of which the said at least one relay contact (8, 9) is switched over and the connection between the output circuit and the secondary winding (7) of the transformer is interrupted.
Patent DE-68910291-T2 (DE)
Inventor: EVANS COLIN MICHAEL
IPC: C07C205/06
Filed: 1989-12-15
Granted: 1994-05-19
Abstract: Process for the mononitration of a nitratable organic compound with a mixed acid in which one of the reactants is delivered into a body of the other reactant in the form of ultra-fine droplets through an atomizing nozzle or similar orifice. The process is economic to construct and operate, is safe and simple to control and leads to a low cost, substantially pure product.
Patent DE-68916005-T2 (DE)
Inventor: MILLER ALAN
IPC: A61C13/30
Filed: 1989-07-26
Granted: 1994-12-22
Abstract: A dental post for retaining a dental restoration onto a tooth stub and a method for making dental post. The dental post includes a cylindrical body portion and a head portion which extends outwardly from the body portion. The body portion is inserted in a bore in the tooth and secured therein by cement. To improve cement retaining capacity of the dental post, there are provided on the body portion non-continuous raised portions, spaced by wide open gaps to retain large segments of thick segments of cement. The overall portion of the gap area surface is greater than that of the land area surface.
Patent DE-68922899-T2 (DE)
Inventor: UEDA TOHRU
IPC: C07H19/06
Filed: 1989-12-05
Granted: 1995-10-12
Abstract: Pyrimidine 2 min -deoxy-2 min -methylidene nucleoside compounds :   <CHEM> wherein R<1> represents amino, hydroxy, silylamino, silyloxy, acylamino or acyloxy; R<2> represents hydrogen, halogen, a lower alkyl, a lower alkenyl, a lower alkynyl or haloalkyl; R<3> and R<4> represent the same or different hydrogen, silyl, acyl or aminoacyl, or a pharmaceutically acceptable salt or hydrate thereof, except that R<1> is amino or hydroxy, and both of R<3> and R<4> are hydrogen. Said compounds possess excellent antitumor and antiviral activities, thus providing novel anticancer and antiviral agent.
Patent DE-68928871-T2 (DE)
Inventor: INANAGA KIYOFUMI
IPC: H04R1/34
Filed: 1989-04-19
Granted: 1999-06-02
Abstract: A loudspeaker (21) comprises a diaphragm (22) having a vibrating portion (215) and an annular conductive portion (28), a current feeding coil (23) facing the conductive portion (28) with a predetermined magnetic gap, and a magnetic circuit (24, 25, 26, 211) comprising a top plate (24), a magnet (25) and a yoke plate (26) to which the current feeding coil (23) is attached. A capacitor which forms a high-pass filter together with the internal resistance of the current feeding coil (23) is connected serially with the current feeding coil (23). <IMAGE>
Patent DE-69002839-T2 (DE)
Inventor: MASINI JEAN-JACQUES
IPC: C07C17/389
Filed: 1990-02-13
Granted: 1994-02-10
Abstract: Process for drying a mixture containing at least one hydrocarbon, hydrochloric acid and water, characterised in that it is placed in contact with a desiccant chosen from (i) anhydrous metal sulphates, chlorides or perchlorates or (ii) phosphorus pentoxide until the desiccant has retained most of the water. This is applied to the synthesis of chloromethanes to dry the methyl chloride leaving the head of the CH3Cl/higher chloromethanes separating column.
Patent DE-69007382-T2 (DE)
Inventor: ENGELHARDT JOHN A
IPC: F16B17/00
Filed: 1990-08-30
Granted: 1994-06-23
Abstract: A structural joint which may be for orthopedic use is effective to simultaneously resist bending and torsional loading. It includes a female member (38) formed with a cone shaped bore (40) and a mouth (42) defining entry into the bore (40). A male member (36) matingly engageable with the female member has a contoured outer surface which includes a coupling element sized and shaped for mating engagement with the bore (40). When the male and female members are joined, the coupling element extends to a location within the bore (40) spaced from the mouth (42) and joins, via a smooth surfaced intermediate element, to a transitional element whose transverse dimension is substantially smaller than the mouth (42) of the bore (40) as it extends through and beyond the mouth (42). The bore (40) and the coupling element may be mutually tapered such that the male and female members become locked together when engaged.
Patent DE-69008774-T2 (DE)
Inventor: LORENZONI LORENO
IPC: A62D101/22
Filed: 1990-06-05
Granted: 1994-09-22
Abstract: The disposal of chlorinated pitches is carried out by means of a process which consists of two treatments with an alkanol, which are carried out in cascade. Such treatments cause the precipitation to take place of the suspended matter, which is then caused to settle, is separated and is pyrolized, whilst the supernatant is distilled in order to separate the alkanol, which is recycled back to the process, and the other organic components, which are sent to further uses.
Patent DE-69009765-T2 (DE)
Inventor: MORONI FLAVIO
IPC: A61P25/00
Filed: 1990-08-07
Granted: 1994-11-24
Abstract: Kynurenic acid derivatives useful as therapeutic agents in treating neurological disorders, for example, thiokynurenic acid, 7-chloro-thio-kynurenic acid, 7-trifluoromethyl-thiokynurenic acid, 7-methoxy-thiokynurenic acid and 5-fluoro-thiokynurenic acid.
Patent DE-69013011-T2 (DE)
Inventor: MOORE KEVIN
IPC: C12N15/65
Filed: 1990-12-18
Granted: 1995-02-23
Abstract: BCRF1 proteins are provided for treating conditions associated with excessive production of IFN- gamma . Also provided are expression vectors for producing BCRF1 proteins. Compositions of the invention are useful in treating a variety of disorders, including allergy, psoriasis, tissue rejection, and MHC-linked autoimmune diseases.
Patent DE-69019524-T2 (DE)
Inventor: NEWTON G
IPC: A61K31/195
Filed: 1990-07-27
Granted: 1996-01-04
Abstract: Feed compositions containing at least 0.6% lysine, preferably between about 0.7 and 0.8% lysine, and between approximately 0.1 to 400 ppm, preferably between 5 and 50 ppm, L-carnitine produce greater weight gains and feed efficiency, and alter fat metabolism, as compared with the same diet in the absence of the carnitine when fed to the finishing pigs. The L-carnitine can also be administered as a feed supplement providing between 0.05 and 15 mg L-carnitine/kg body weight/day, most preferably between 0.1 and 2.0 mg L-carnitine/kg body weight/day. The effect of the carnitine is sex linked, with significantly greater weight gains and feed efficiency observed for gilts than for barrows.
Patent DE-69019927-T2 (DE)
Inventor: GRAYSON JAMES IAN
IPC: C07C225/16
Filed: 1990-12-03
Granted: 1995-12-07
Abstract: The present invention relates to the preparation of aminoalkyl p-hydroxyphenyl ketones. Certain of these ketones are well known as important intermediates in the production of compounds having pharmaceutical activity, for example octopamine or synephrine. The known Houben-Hoesch reaction is a variation of the Friedel-Crafts reaction and involves the condensation of a phenolic substrate with a nitrile in the presence of a Lewis acid catalyst to give a hydroxy-aryl ketone. It is an object of the invention to provide a new or improved process for the manufacture of aminoalkyl p-hydroxyphenyl ketones. According to the invention, there is provided a process for the preparation of an aminoalkyl p-hydroxyphenyl ketone comprising reacting phenol with a nitrile, in the presence of a Lewis acid catalyst, to cause condensation thereof, the process being characterised in that the reaction is carried out in a medium comprising a nitroalkane solvent for the reactants. A preferred but non-limiting feature of the invention is the productiqn of 2'amino-4-hydroxyacetophenones. The present invention is based on the surprising discovery that nitroalkanes are unexpectedly much better solvents for this reaction, being less toxic, giving a better yield and also ensuring a homogeneous reaction medium. The nitroalkanes may also be diluted with a halogenated hydrocarbon solvent, which acts as an inert diluent, thus reducing the amount of nitroalkane used, and making the reaction less hazardous.
Patent DE-69108872-T2 (DE)
Inventor: MILANI DANIEL
IPC: E04D13/14
Filed: 1991-12-03
Granted: 1995-08-24
Abstract: Device (6) for sealingly connecting between, on the one hand, the border (5) of a panelled floor (3) suspended above a platform (1) and, on the other hand, an adjacent wall (2) erected above the said platform, the latter being covered by an impervious covering (7) with a stand-up flashing member (7a) against the said wall, rising between the border panels (5) and the said wall (2), characterised in that the device includes a sectional profile (8), which comprises a longitudinal element (9) arranged so as to be fixed to the wall (2), a flange (13) suspended from the said longitudinal element, extending some distance away from the lower plane determined by the base of the longitudinal element (9) in order to make, with the said wall, an interstice (14) which receives the stand-up flashing member of the impervious covering, a support flange (10) extending substantially perpendicularly to the suspended flange (13), on the other side of the said interstice, in order to receive, in a bearing fashion, the border panels (5) of the false floor, and a sealing means (15) gripped between the sectional profile and the said wall, in order to protect the top of the stand-up flashing member. <IMAGE>
Patent DE-69109589-T2 (DE)
Inventor: EGEN NED BARRY
IPC: G01N27/26
Filed: 1991-02-11
Granted: 1995-09-07
Abstract: A preparative scale multi-mode electrical separator, which is matrix-free and may be operated in both a batch mode and a continuous, flow-through mode is provided. It may be scaled according to the solution quantities which are to be processed. An internal cooling system whereby the process fluid is always in close proximity to a chilled surface assures an efficient heat dissipation during the separation and concentration processes and also allows the use of higher voltage gradients and shorter separation times than prior designs of electrophoretic separators. Electroosmotic mixing is reduced by providing internal, compartmentation of sample fractions, focusing is improved and focusing times are decreased. Different electrophoretic methods, including zone electrophoresis, isoelectric focusing, counterflow gradient focusing or electrodialysis, may be used with the separator. It may be applied to the purification of proteins, ions, and microorganisms, and for water purification. <IMAGE>
Patent DE-69114363-T2 (DE)
Inventor: LEVY JEFFREY NEAL
IPC: C12P41/00
Filed: 1991-06-06
Granted: 1996-04-25
Abstract: An enantiomerically selective process for acylating racemic 3-amino azetidinone intermediates is provided using penicillin G amidase(acylase) as biocatalyst.
Patent DE-69117305-T2 (DE)
Inventor: RYDIN BJOERN
IPC: D21F7/10
Filed: 1991-12-17
Granted: 1996-08-22
Abstract: PCT No. PCT/SE91/00867 Sec. 371 Date Jun. 18, 1993 Sec. 102(e) Date Jun. 18, 1993 PCT Filed Dec. 17, 1991 PCT Pub. No. WO92/11412 PCT Pub. Date Jul. 9, 1992.A woven fabric, such as a base fabric for a press felt, which is designed for a papermaking machine or the like has along each one of two end edges a plurality of seam loops to be included in a loop seam to form an endless woven fabric. The fabric is characterized in that there is provided, at least at one of the end edges, at least one string of material, preferably in the form of one or more extra yarn threads, extended substantially parallel to the above-mentioned one end edge adjacent the regular thread system of the fabric. The extra yarn thread or threads are woven to only such portions of the seam loops as are facing a first side of the fabric, preferably the paper side thereof. In this manner, there is formed in the seam zone a type of extension of the regular thread system of the fabric, whereby the loop seam is conformed to the rest of the fabric to avoid markings in a paper web at the loop seam.
Patent DE-69122365-T2 (DE)
Inventor: PLESS BENJAMIN
IPC: A61N1/39
Filed: 1991-12-12
Granted: 1997-02-06
Abstract: A programmable implantable medical device utilizable for delivering a configurable defibrillation waveform to a heart. The device includes defibrillation electrode means adapted to be connected to the heart for delivering a multiphasic defibrillation waveform thereto. A programmable waveform generator connected to the heart generates the multiphasic waveform such that at least one phase of the defibrillation waveform has programmed constant tilt. <IMAGE>
Patent DE-69126758-T2 (DE)
Inventor: FUJIWARA HIROMICHI
IPC: A61K31/40
Filed: 1991-10-16
Granted: 1998-02-12
Abstract: A benzamide derivative represented by the formula: <CHEM> having a promoting activity of gastrointestinal tract and pharmacentical composition containing the same.
Patent DE-69129459-T2 (DE)
Inventor: BADGER ALISON MARY
IPC: A61K31/155
Filed: 1991-08-07
Granted: 1998-10-15
Abstract: A pharmaceutical composition containing a non-specific (NS) suppressor cell inducing compound and a non-NS suppressor cell inducing immunosuppressive compound and a pharmaceutically acceptable carrier or diluent, and method of inducing an immunosuppressive effect in a mammal, including a human, in need thereof which comprises administering an effective dose of a NS suppressor cell inducing compound and a non-NS suppressor cell inducing immunosuppressive compound to such mammal.
Patent DE-69131546-T2 (DE)
Inventor: EFFLAND RICHARD C
IPC: C07D498/14
Filed: 1991-05-23
Granted: 2000-03-23
Abstract: There are disclosed various compounds of the formula below, <CHEM>  where   X   is hydrogen, halogen or loweralkyl; Y   is hydrogen, halogen, loweralkyl, loweralkoxy or trifluoromethyl;   R1   is hydrogen, loweralkyl, aryl, arylloweralkyl, diloweralkylaminoloweralkyl or <CHEM>  R3 being hydrogen, loweralkyl or arylloweralkyl; and R2   is hydrogen, loweralkyl or arylloweralkyl; which compounds are useful as analgesic agents, and a process for their preparation.
Patent DE-69201626-T2 (DE)
Inventor: ORTIZ MARK S
IPC: A61B17/128
Filed: 1992-10-16
Granted: 1995-07-27
Abstract: A surgical device (10) and cooperating cartridge (78) for applying surgical clips (12) during endoscopic surgery. The surgical device includes a jaw assembly (18), a barrel assembly (20), and a handle assembly (22). The jaw assembly has movable jaw members, each including a substantially transverse grooved portion (28) and at least one angular side shield (34) extending inwardly from an upper and a lower portion of the jaw member. The jaw members are oriented at an angle of approximately 22 DEG  relative to the longitudinal axis of the barrel portion. The distal surface of each jaw member is oriented at an angle that extends distally and outwardly. The jaw members are insertable into a unique cooperating cartridge that retains the surgical clip. <IMAGE>   <IMAGE>
Patent DE-69203184-T2 (DE)
Inventor: BENE BERNARD
IPC: A61M1/16
Filed: 1992-09-09
Granted: 1996-01-18
Abstract: An artificial kidney comprises measurement means (27) for measuring at least one characteristic of the fresh dialysis liquid and of the used liquid. These measurement means (27) are located in a pipe portion common to a branch (28) on the supply pipe (13) for fresh dialysis liquid, and to a branch (29) on the pipe (14) for draining used liquid. Valve means (30, 31, 32) are provided to allow the circulation of liquid exclusively in either branch. By virtue of this arrangement, it is possible to obtain, by calculation, as often as is desired, the value of characteristics of the blood of a patient, and to adjust continuously the functioning of the kidney for a therapeutic objective chosen by the doctor. <IMAGE>
Patent DE-69204627-T2 (DE)
Inventor: IVANICS JOZSEF
IPC: A61K31/557
Filed: 1992-06-19
Granted: 1996-05-02
Abstract: The invention relates to a novel process for the preparation of 13,14-dihydro-15 (R)-17-phenyl-18,19,20-trinor-PGF2 alpha  isopropyl ester of the formula (I)-wherein R stands for saturated or unsaturated straight, branched or cyclic C1-7 alkyl or phenyl or benzyl group-    <IMAGE>  (I)
Patent DE-69208358-T2 (DE)
Inventor: MAXSON RICHARD CHARLES
IPC: B01D24/22
Filed: 1992-08-04
Granted: 1996-06-27
Abstract: Underdrain lateral system, which is especially adapted for use in a gravity filter bed, includes, as its preferred embodiment, scallop-shaped laterals (26, 126) having an upper, wrapped wire, slotted screen surface (28). The screen surface supports and retains the filter media particles (118) directly, without the necessity of an underlying gravel layer, and is itself supported by channel-shaped rod members (34) which are welded to the wires (30). The web portions (36) of the channel-shaped rod members perform the function of simultaneously distributing air and water during backwashing, and include a smaller total area of apertures (38) in upper channels and a larger total area of apertures (40) in lower channels to cause a plenum (56) to be formed inside the laterals which ensures that the distribution of air and water will be uniform throughout the lateral, even if the lateral is not perfectly level. Distribution of the air and water throughout all of the laterals is made even more uniform by mounting the laterals on a header (124) and providing perforated flow tubes (122) which extend from each lateral into the header to produce an additional air plenum (135) therein. <IMAGE>   <IMAGE>
Patent DE-69224536-T2 (DE)
Inventor: MACDONALD BRUCE
IPC: B23K26/00
Filed: 1992-07-01
Granted: 1998-09-10
Abstract: The apparatus for machining and material processing includes an excimer laser and a Fresnel zone plate array (FZP) positioned parallel to the workpiece, with the distance between the FZP and the workpiece being the focal length of the FZP. For each hole to be formed on the workpiece a corresponding Fresnel zone is patterned onto the FZP. Each Fresnel zone may be patterned directly centered over the desired hole location or in high density patterns it may be located off-center from the hole with deflection being accomplished by the formation of finer circular arcs on the side of the Fresnel zone opposite the desired direction of deflection. A beam scanner is included to provide a more uniform illumination of the FZP by the laser beam. The scanning eliminates non-uniformity of intensity. The alignment mechanism uses a helium-neon laser, the beam from which is projected onto a surface relief grating on the workpiece. The reflected light from the surface relief grating is filtered to create interference fringes which, when aligned, provide maximum light intensity projected through a transmission grating on the Fresnel zone plate.
Patent DE-69309638-T2 (DE)
Inventor: AUDOUSSET MARIE-PASCALE
IPC: A61K8/46
Filed: 1993-12-28
Granted: 1997-07-24
Abstract: Use of benzimidazole derivatives as coupling agents for the oxidation dyeing of keratinous fibres and in particular human hair, in the presence of at least one meta-phenylenediamine and at least one para and/or ortho oxidation dye precursor, the benzimidazole derivative corresponding to the formula: <IMAGE>  in which:     R1 represents a hydrogen atom or a C1-C4 alkyl radical; R2 represents a hydrogen atom or a C1-C4 alkyl radical or a phenyl radical;   R3 represents a hydroxyl, amino or methoxy radical; R4 represents a hydrogen atom, a hydroxyl or methoxy radical or a C1-C4 alkyl radical;  with the proviso that:     - when R3 denotes NH2, it occupies the 4-position;   - when R3 is in the 4-position, R4 is in the 7-position; - when R3 is in the 5-position, R4 is then in the 6-position.