baber/WOPTO huggingface dataset:
Patent JP-2667051-B2 (JP)
IPC: A61K38/095
Filed: 1990-10-19
Granted: 1997-10-22
Abstract: A liposome composition for localizing an anti-tumor compound to a solid tumor via the bloodstream. The liposomes, which contain the agent in entrapped form, are composed of vesicle-forming lipids and between 1-20 mole percent of a vesicle-forming lipid derivatized with hydrophilic biocompatible polymer, and have sizes in a selected size range between 0.07 and 0.12 microns. After intravenous administration, the liposomes are taken up by the tumor within 24-48 hours, for site-specific release of entrapped compound into the tumor. In one composition for use in treating a solid tumor, the compound is an anthracycline antibiotic drug which is entrapped in the liposomes at a concentration of greater than about 50  mu g agent/ mu mole liposome lipid. The method results in regression of solid colon and breast carcinomas which are refractory to anthracycline antibiotic drugs administered in free form or entrapped in conventional liposomes.
Patent JP-H0666358-B2 (JP)
IPC: C07K14/00
Filed: 1989-12-15
Abstract: A method of forming solder bumps includes the steps of applying a thick layer of solder resist (22) to a substrate (20). The resist is selectively removed to provide wells (23) at solder pads (21) on the substrate. The solder paste (24) is applied to the substrate in the wells. The solder paste is reflowed to form solder bumps (25) on the pads. A socket for a solder bumped member (36) is obtained by first providing a substrate (30) having metallized pads corresponding to the solder bumps of the member. A thick layer of photo definable solder resist (32) is applied to the substrate. The resist is selectively removed to provide wells (33) at the metallized pads (31) of the substrate. Solder paste (34) is then deposited in the wells. The solder bumped member (36) can then be positioned so that the solder bumps (37) are located in the wells. The solder paste (34) is reflowed to bond to the solder bumps (37) and the metallized pads (31). The solder paste (34) can be selected to have a lower melting temperature than the solder bumps (37). By reflowing the solder paste (34) at a temperature lower than the melting temperature of the solder bumps (37), the paste can wet to and blend with the solder bumps while not causing the solder bumps to reflow.
Patent JP-2674599-B2 (JP)
IPC: C09D133/06
Filed: 1987-03-13
Granted: 1997-11-12
Abstract: PCT No. PCT/EP87/00148 Sec. 371 Date Sep. 27, 1989 Sec. 102(e) Date Sep. 27, 1989 PCT Filed Mar. 13, 1987 PCT Pub. No. WO87/05921 PCT Pub. Date Oct. 8, 1987.The invention relates to aqueous two-component lacquers containing pigments and other customary additives for single-layered coating of finish film and continuous edges. The two-component lacquers according to the invention are such lacquers in which the first component (component (A)) contains 0.1 to 15% by weight, preferably 2 to 10% by weight, based on the total weight of component (A), of a blocked acid as a potential hardening catalyst and 10 to 90% by weight, preferably 20 to 65% by weight, based on the total weight of component (A), of an aqueous dispersion of a self-crosslinking polyacrylate, in which the polyacrylate contains, as the groups which facilitate self-crosslinking, acid amide derivative groups which correspond to the general structural formula -CO-N(R1)-CH(R2)-OR3, in which R1=an H atom or a -CH(R2)-OR3 grouping, R2=an H atom or a -COOR4 group, R3=an H atom or a hydrocarbon radical containing 1 to 10 C atoms, preferably a methyl, ethyl, (iso)propyl or (iso)butyl radical, and R4=an alkyl radical with 1 to 5 C atoms, and the second component (component (B)) contains 20 to 90% by weight, preferably 70 to 90% by weight, based on the total weight of component (B), of a melamine resin dispersed or dissolved in an aqueous medium or of a melamine/urea resin mixture dispersed or dissolved in an aqueous medium, and components (A) and (B) are mixed before application in a ratio such that 0.4 to 1.0, preferably 0.6 to 0.8 part by weight of melamine resin or 0.4 to 1.5, preferably 1.0 to 1.2 parts by weight of melamine/urea resin mixture are present per part by weight of self-crosslinking polyacrylate resin.
Patent JP-4024297-B2 (JP)
IPC: C11D3/39
Filed: 1996-05-28
Granted: 2007-12-19
Abstract: Disclosed are nonaqueous, particulate-containing liquid laundry detergent compositions which are in the form of a suspension of particulate material, preferably including peroxygen bleaching agent and an organic detergent builder, dispersed in a liquid phase containing an alkylbenzene sulfonate anionic surfactant, an alcohol ethoxylate nonionic surfactant and a nonaqueous, low-polarity organic solvent. Such compositions provide especially desirable cleaning and bleaching of fabrics laundered therewith and also exhibit especially desirable pourability and chemical and phase stability.
Patent JP-2554730-B2 (JP)
IPC: G01R29/12
Filed: 1988-07-05
Granted: 1996-11-13
Abstract: Sensor systems and methods for detecting the position and/or movement of an object in multiple degrees of freedom. The sensor system of the present invention comprises at least one field-effect transistor (FET), the geometrical configuration of the FET being selected so as to provide the desired sensitivity. The FET is preferably provided with a conductive gate adjacent to but insulated from the channel region of the FET. An object whose position and/or movement is to be detected is prepared such that an electric field emanates from the object. The FET is brought into the vicinity of the object, and the electric field emanating from the object interacts with the gate and/or channel region of the FET so as to modify the magnitude of the electrical current flowing through the channel region. The current through the channel region is detected and is used to obtain information about the position and movement of the object relative to the channel region of the FET. By positioning a plurality of substantially coplanar FETs in the vicinity of the object, the position and/or movement of the object in any desired number of degrees of freedom can be detected and monitored.
Patent JP-3112088-B2 (JP)
IPC: G01N7/00
Filed: 1992-05-02
Granted: 2000-11-27
Abstract: PCT No. PCT/DE92/00359 Sec. 371 Date Oct. 12, 1993 Sec. 102(e) Date Oct. 12, 1993 PCT Filed May 2, 1992 PCT Pub. No. WO92/21013 PCT Pub. Date Nov. 26, 1992.The invention relates to a process for the continuous determination of the dust content of flowing media with the isokinetic flow sampling with the separation of the dust or aerosols by cake filtration on a filter and the measurement of the pressure drop at the filter to determine its degree of clogging. To this end the time cycle of the quantity of dust separated on the filter is determined by the measurement of the pressure loss at the filter of an isokinetically operating sampling system. To find the dust load, this quantity of dust is related to the partial quantity of gas extracted isokinetically during the period concerned.
Patent JP-3174057-B2 (JP)
IPC: D21F1/10
Filed: 1992-11-20
Granted: 2001-06-11
Abstract: PCT No. PCT/SE92/00798 Sec. 371 Date Sep. 6, 1994 Sec. 102(e) Date Sep. 6, 1994 PCT Filed Nov. 20, 1992 PCT Pub. No. WO93/10304 PCT Pub. Date May 27, 1993.The invention relates to a woven machine clothing comprising at least two warp thread systems (3, 5) and one weft thread system (4). Characteristic of the invention is that the two warp thread systems (3, 5) have been interlaced with each other by thread twisting alternately clockwise (at 4b/6b) and counterclockwise (4f/6f).
Patent JP-3199742-B2 (JP)
IPC: A23L1/304
Filed: 1993-10-18
Granted: 2001-08-20
Abstract: Sweetener supplement compositions which provide a bioavailable source of calcium containing a) soluble calcium; b) an edible acid component comprising a mixture of citric acid and malic acid wherein said mixture has a weight ratio of citric acid to malic acid of from about 90:10 to about 10:90; and c) sugar; in which the weight ratio of the edible acid component to the soluble calcium is from about 3:1 to about 17:1; sugar comprises at least 15%, on a dry weight basis, fructose and the weight ratio of sugar to edible acid component is from about 1:1 to about 40:1.
Patent JP-2564992-B2 (JP)
IPC: H04L27/12
Filed: 1990-07-09
Granted: 1996-12-18
Abstract: A method is described for transmitting digital data with minimum splatter and for recovering the same with a conventional frequency modulated (FM) receiver to obtain data having minimum intersymbol interference. The method utilizes an optimized prototype pulse which has been predistorted to match the inverse characteristics of the post detection low pass filter in a conventional FM receiver. When the optimized electric pulse is received and processed by the post detection low pass filter of the conventional FM receiver, a pulse shape exhibiting minimal intersymbol interference is produced.
Patent JP-3109101-B2 (JP)
IPC: C02F1/72
Filed: 1995-10-05
Granted: 2000-11-13
Abstract: An antimicrobial solid material having a satisfactory antimicrobial activity for a long term against sewage in any form of circulating, static and flowing waters or contacting portions thereof and a utilizing method thereof are provided. An antimicrobial solid material as one embodiment of the present invention comprises both of an antimicrobial metal ion and an antimicrobial metal in a metal state. In general, it is believed that antimicrobial metal ions have a potent antimicrobial effect when they exist in a liquid to be treated with a certain concentration or more, but they are rapidly released and exhausted so that their antimicrobial effects cannot last long. On the other hand, it is believed that the antimicrobial metal in a metal state does not have a prompt effect, but exhibits a certain bacteriostatic and fungistatic effect continuously for a long term. Therefore, the antimicrobial solid material containing both of the antimicrobial metal ions and the antimicrobial metal in a metal state thereof has both of a potent initial antimicrobial activity and an enduring bacteriostatic and fungistatic activity. <IMAGE>
Patent JP-3656756-B2 (JP)
IPC: B29C67/00
Filed: 1993-02-12
Granted: 2005-06-08
Abstract: PCT No. PCT/EP93/00344 Sec. 371 Date Aug. 26, 1994 Sec. 102(e) Date Aug. 26, 1994 PCT Filed Feb. 12, 1993 PCT Pub. No. WO93/16865 PCT Pub. Date Sep. 2, 1993The invention relates to a process for the production of porous shaped articles having a predetermined pore structure by shaping a composition which can undergo plastic deformation and then be solidified, which is characterized in that the shaped article is built up in the form of layers by repeated sequence of the steps A. Production of a layer of the composition structured in an image-wise manner corresponding to the pore system, and B. Solidification of the layer the image structures of the individual layers being transferred from corresponding models. This process can preferably be used for the production of shaped articles having a three-dimensionally interconnecting pore system, and in particular for the production of shaped implants having the pore system of natural bone.
Patent JP-H0772175-B2 (JP)
IPC: C07D491/044
Filed: 1991-08-20
Abstract: The present invention relates to novel fused ring analogs of nitrogen containing heterocycles, and specifically, to compounds of formula (I), wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<8>, x, y, and z and m are defined as below. These novel compounds are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders.
Patent JP-3497169-B2 (JP)
IPC: C10N30/16
Filed: 1994-12-12
Granted: 2004-02-16
Abstract: An aqueous functional fluid composition free of formaldehyde and formaldehyde producing agents, more especially an aqueous metalworking fluid composition, having improved resistance to attack by microorganisms is provided. This fluid comprises a) water, b) a water soluble or dispersible functioning agent (e.g. water soluble or dispersible organic lubricant) and c) an antimicrobial effective amount of the combination of d) a water soluble or dispersible nitrogen bearing organic compound (e.g. monoethanolamine) and e) a water soluble or dispersible haloalkynylalkyl carbamate (e.g. 1-iodo-3-propynylbutyl carbamate).
Patent JP-3418393-B2 (JP)
IPC: C07C51/215
Filed: 1991-09-26
Granted: 2003-06-23
Abstract: Shaped oxidation catalyst structures containing catalytic material comprised of mixed oxides of vanadium and phosphorus which are useful for the production of maleic anhydride via the partial oxidation of nonaromatic hydrocarbons, particularly n-butane, in the vapor phase with molecular oxygen or a molecular oxygen-containing gas are provided. Such structures are characterized by exhibiting (a) a geometric volume of from about 30 percent to about 90 percent of that exhibited by the void space-free solid geometric form, (b) an external geometric surface area/geometric volume ratio of at least about 15 cm<-1>, (c) a bulk density of from about 0.4 g/cm<3> to about 1.4 g/cm<3>, and (d) a mechanical resistance sufficient to maintain substantially the structural integrity of the shaped structure under handling and use conditions.
Patent JP-3401003-B2 (JP)
IPC: A61M5/168
Filed: 1993-04-28
Granted: 2003-04-28
Abstract: PCT No. PCT/FR93/00410 Sec. 371 Date Jun. 9, 1994 Sec. 102(e) Date Jun. 9, 1994 PCT Filed Apr. 28, 1993 PCT Pub. No. WO93/21977 PCT Pub. Date Nov. 11, 1993A device for controlling the flow of a medicinal substance in an infusion tube by means of a valve comprising a sealing means and a circuit (24) for controlling the position of the sealing means. The valve includes a chamber (10) with an inlet (12) and an outlet (14), a bi-metallic strip (16) arranged within the chamber (10) and secured to one of its walls (18), a ball (20) secured to the bi-metallic strip (16) for partially or entirely sealing off the inlet (12), and a control circuit (24) for controlling the voltages (V1, V2) applied to said strip (16) in order to provided continuous and accurate control of the flow of medicinal substance through the valve.
Patent JP-4016070-B2 (JP)
IPC: C07J71/00
Filed: 1996-12-04
Granted: 2007-12-05
Abstract: PCT No. PCT/EP96/05390 Sec. 371 Date Jun. 5, 1998 Sec. 102(e) Date Jun. 5, 1998 PCT Filed Dec. 4, 1996 PCT Pub. No. WO97/21722 PCT Pub. Date Jun. 19, 1997A process for preparing the compound (11 beta ,16 beta )-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione (INN deflazacort) which comprises reacting (11 beta ,16 beta )-11,21 -dihydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione with acetic anhydride in a suitable organic solvent in the presence of a basic catalyst and water.
Patent JP-2950520-B2 (JP)
IPC: A61K8/00
Filed: 1994-04-01
Granted: 1999-09-20
Abstract: The present invention describes a method for targeted and specific delivery of beneficial compounds, including hair dyes, melanin, proteins, and nucleic acids for gene therapy, to hair follicle cells using liposomes encapsulating the beneficial compound. Particularly preferred methods describe delivery of hair dyes, melanin or tyrosinase to the hair follicle for the purpose of improving hair color or condition, the delivery of compounds which prevent alopecia or stimulate hair growth, either by encapsulating a compound in liposomes, or by encapsulating a nucleic acid capable of expressing a protein in liposomes. Also described are liposome compositions for practicing the methods.
Patent JP-4538105-B2 (JP)
IPC: H04W52/60
Filed: 1998-01-21
Granted: 2010-09-08
Abstract: According to the proposed method, the frequency of power control commands transmitted on a power control channel is changed according to the traffic. When the traffic becomes slower in at least one direction due to a DTX state, a slower transfer rate, asymmetric data transfer or for any other reason, the frequency of power control commands is lowered. Both the base station and the personal station may lower the frequency of the commands which they send. An alternative to changing the frequency of power control commands is to change the energy of power control bits. The duration of power control bits must hereby be extended, if a standard bit error ration is desired. If the system is frequency-divided and/or time-divided and uses frequency control command of several bits, the length of the command word may be shortened in addition to or as an alternative to the change in frequency. The power control algorithm may be changed several times during a traffic connection.
Patent JP-4011115-B2 (JP)
IPC: C12N15/62
Filed: 1996-04-11
Granted: 2007-11-21
Abstract: Provided by the present invention are novel methods of protein recovery and purification methods and more specifically novel methods for the recovery and purification thioredoxin fusion proteins, especially of IL-11.
Patent JP-3369190-B2 (JP)
IPC: G06F21/62
Filed: 1998-02-05
Granted: 2003-01-20
Abstract: In a microcomputer intended for executing a multiplicity of user programs, a memory management unit ensures that none of the user programs can access other programs. However, in order to be able to use common library programs, and at the same time to prevent unchecked access to them, a vector memory area is provided which contains the start addresses of library programs as jump destinations. A library program is called by specifying the vector number, from which the memory management units determines he corresponding address in the vector memory area.
Patent JP-4435311-B2 (JP)
IPC: A61B1/307
Filed: 1999-04-07
Granted: 2010-03-17
Abstract: A flexible trocar assembly includes an inner flexible tube and a concentric outer flexible tube. The flexible tubes are spaced apart from each other so as to form an open ended annular space in the trocar assembly. The annular space contains surgical instrumentation and passages for inflation gases, trocar assembly rigidifying gases or materials, and trocar manipulating mechanisms. For example, fiber optic light transmitters associated with camera-related fiber optics can be disposed in the annular space so that an area in a body cavity being examined can be illuminated and observed. Trocar manipulating mechanisms such as Bowden cables can also be disposed in the annular space. Liquid flushing tubes can be positioned in the annular space. Carbon dioxide or air injecting tubes can be positioned in the annular space. The inner flexible tube defines a central trocar assembly passage through which surgical instruments can be inserted into the body cavity. The trocar assembly is particularly useful in performing surgical procedures in the colon. An invertable tube assembly is associated with the trocar assembly and is used to move the trocar assembly into and out of the body cavity. The invertible tube embraces the trocar assembly and the invertible tube is moved forward and backward by a controlled drive mechanism. Lubrication is provided between the invertible tube and the trocar assembly so as to reduce friction between the invertible tube drive mechanism and the trocar assembly.
Patent ES-2293849-B2 (ES)
Title: Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
Inventor: GRAS ESCARDO JORDI
IPC: A61K31/655
Filed: 2005-05-31
Granted: 2009-04-16
Abstract: Combinaciones que comprenden agentes antimuscarínicos y agonistas beta-adrenérgicos. Una combinación que comprende (a) un {be}2 agonista y (b) un antagonista de los receptores M3 muscarínicos, el cual es 3R-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo[2,2,2]octano, en forma de una sal que contiene un anión X, el cual es un anión farmacéuticamente aceptable de un ácido mono o polivante.
Patent AU-2001270696-B2 (AU)
Title: Method for culturing micro-organisms in reducing conditions obtained by a gas stream
Inventor: DIVIES CHARLES
IPC: C12G1/02
Filed: 2001-06-28
Granted: 2007-03-15
Abstract: The present invention relates to a method of culturing microorganisms which makes it possible to reduce the oxidation-reduction potential of the culture medium, characterized in that the said culture is carried out under reducing conditions obtained by a reducing gas compared with air comprising hydrogen. It also relates to such a method for modifying the metabolic flows during the culture of the microorganisms. It applies more particularly to the food sector and in particular to the production of alcoholic beverages.
Patent AU-2002242226-B2 (AU)
Title: Carbamate compounds for use in preventing or treating bipolar disorder
Inventor: CHOI YONG MOON
IPC: A61P25/24
Filed: 2002-02-21
Granted: 2006-06-29
Abstract: This invention is directed to a method for preventing or treating bipolar disorder comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of Formula (I) or enantiomeric mixture wherein one enantiomer of Formula (I) predominates: wherein phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and, R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3 </SUB>and R<SUB>4 </SUB>are independently selected from the group consisting of hydrogen and C<SUB>1</SUB>-C<SUB>4 </SUB>alkyl; wherein C<SUB>1</SUB>-C<SUB>4 </SUB>alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C<SUB>1</SUB>-C<SUB>4 </SUB>alkyl, C<SUB>1</SUB>-C<SUB>4 </SUB>alkoxy, amino, nitro and cyano).
Patent AU-2002300354-B2 (AU)
Title: Mobile Telephone Communications Networks
Inventor: WOO CHIU MAN CLIFF
IPC: H04W4/40
Filed: 2002-08-01
Granted: 2008-07-31
Abstract: A mobile communications system for a passenger carrying vessel includes repeaters for relaying radio frequency signals to mobile telephone on the vessel from communications networks in geographically separated locations. Each repeater is controlled to operate at different required gains to maintain signal levels for the telephones at a suitable level, as the passenger carrying vessel moves from one location to another location through the middle region. A computer is programmed to alter the gains of the repeaters according to respective signal strengths of received signals and to determine and control a hand-over at some position according to the signal strengths, when the vessel is within the middle region. The hand-over, and in some cases the gains, may be determined or influenced by the computer in accordance with GPS signals received by the vessel. <IMAGE>
Patent AU-2002304163-B2 (AU)
Title: Polypeptide unstabilizing protein in cells under aerobic conditions and DNA encoding the same
Inventor: KONDOH SHINAE
IPC: C07K14/47
Filed: 2002-06-04
Granted: 2007-05-17
Abstract: DNA encoding a polypeptide (LDLEMLAPYIPMDDDFQL) (I), or encoding a fusion protein containing at least 16 residues of (I), a nuclear localization signal, and another protein, and imparting relative stability under specific conditions of oxygen concentration within the cell, is new. Independent claims are also included for the following: (1) Vectors containing the DNA; (2) Cells transformed by the vectors; (3) Producing the fusion protein by culture of the transformed cells; (4) Detecting hypoxic conditions in cells by monitoring the stability of the protein fused to (I) in cells transformed by vectors containing the DNA; (5) Regulating the stability of proteins within the cell by transformation with the DNA; (6) Inhibiting the development of cells under hypoxic conditions, using the fusion protein; (7) Fusion proteins encoded by the DNA; and (8) Stabilization of cells under specific conditions of oxygen tension. ACTIVITY : Cytostatic. No biological data given. MECHANISM OF ACTION : Stabilization of a cytotoxic protein within cells in hypoxic regions of a solid tumor; Gene Therapy. No biological data given.