baber/WOPTO huggingface dataset:
Patent EP-2050744-A1 (EP)
Inventor: HENNEQUIN LAURENT FRANCOIS ANDRE
IPC: C07D471/04
Filed: 2000-02-08
Abstract: The invention relates to the use of compounds of the formula I:
     
wherein ring C is an 8, 9, 10, 12 or 13-membered bicyclic or tricyclic moiety which optionally may contain 1-3 heteroatoms selected independently from O, N and S; Z is -O-, -NH-, -S-, -CH 2 - or a direct bond; n is 0-5; m is 0-3; R 2  represents hydrogen, hydroxy, halogeno, cyano, nitro, trifluoromethyl, C 1-3 alkyl, C 1-3 alkoxy, C 1-3 alkylsulphanyl, -NR 3 R 4  (wherein R 3  and R 4 , which may be the same or different, each represents hydrogen or C 1-3 alkyl), or R 5 X 1 - (wherein X 1  and R 5  are as defined herein; R 1  represents hydrogen, oxo, halogeno, hydroxy, C 1-4 alkoxy, C 1-4 alkyl, C 1-4 alkoxymethyl, C 1-4 alkanoyl, C 1-4 haloalkyl, cyano, amino, C 2-5 alkenyl, C 2-5 alkynyl, C 1-3 alkanoyloxy, nitro, C 1-4 alkanoylamino, C 1-4 alkoxycarbonyl, C 1-4 alkylsulphanyl, C 1-4 alkylsulphinyl, C 1-4 alkylsulphonyl, carbamoyl,  N- C 1-4 alkylcarbamoyl,  N , N -di(C 1-4 alkyl)carbamoyl, aminosulphonyl,  N -C 1-4 alkylaminosulphonyl,  N , N -di(C 1-4 alkyl)ammosulphonyl,  N -(C 1-4 alkylsulphonyl)amino,  N- (C 1-4 alkylsulphonyl)- N -(C 1-4 alkyl)amino,  N , N -di(C 1-4 alkylsulphonyl)amino, a C 3-7 alkylene chain joined to two ring C carbon atoms, C 1-4 alkanoylaminoC 1-4 alkyl, carboxy or a group R 56 X 10  (wherein X 10  and R 56  are as defined herein); and salts thereof, in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals, processes for the preparation of such compounds, pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof as active ingredient and compounds of formula I. The compounds of formula I and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.
Patent EP-2186662-A1 (EP)
Inventor: RUNKEL WALTER DR
IPC: B60G11/30
Filed: 2008-11-18
Abstract: The device (1) has a spring cylinder (2) with a piston (6) that is guided in a cylinder (4). The piston provided inside the cylinder separates two working chambers (10, 12) from each other to define the working chambers, where one of the working chambers is associated with a spring medium (FM) and the other working chamber is associated with a damping medium (DM). The latter working chamber is connected via a damper valve arrangement (14) to a hydraulic container (16) to pressurize the damping medium to a defined initial pressure of about 3 to 5 bar.
Patent EP-2191893-A1 (EP)
Inventor: STOECKER WINFRIED
IPC: B01L3/00
Filed: 2008-11-19
Abstract: Device comprises entity holder having one or several elongate adhesive surfaces and reagent holder having one or several channels. The entity holder is detachably connected to the reagent holder, and in case reaction partners bound to a solid phase are disposed on the elongate adhesive surfaces and reactants dissolved in liquid are present in the channels, and the reaction partners and the reactants are in contact, a unit for preventing the liquid from passing from one channel to an adjacent channel is provided. Device comprises entity holder having one or several elongate adhesive surfaces and reagent holder having one or several channels. The entity holder is detachably connected to the reagent holder in such a manner that the elongate adhesive surfaces each face a respective one of the channels, and in case reaction partners bound to a solid phase are disposed on the elongate adhesive surfaces and reactants dissolved in liquid are present in the channels, and the reaction partners and the reactants are in contact, a unit for preventing the liquid from passing from one channel to an adjacent channel is provided. An independent claim is included for performing immunological, histochemical and cytochemical, molecular biological, enzymological or clinical-chemical analysis, or other analysis, which involves connecting the entity holder to the reagent holder, introducing liquid dissolved with reactants into the channels such that solid-phase substrates having reaction partners bound to it and being disposed on the adhesive surfaces contact the liquid, and moving the entity holder and the reagent holder together in such a manner that the liquid alternately moves into the two longitudinal directions of the channels.
Patent EP-2202298-A1 (EP)
Title: Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV
IPC: G01N33/569
Filed: 2008-12-23
Abstract: The invention relates to a recombinant classical swine fever virus (CSFV). A preferred recombinant CSFV comprises a deletion of at least one amino acid in a "TAVSPTTLR" domain of the E2 protein. The invention further relates to a vaccine comprising the recombinant CSFV, a method for generating a recombinant CSFV, and use of a recombinant CSFV.
Patent EP-2042114-A1 (EP)
Inventor: SMITH ROBERT
IPC: A61B17/34
Filed: 2008-09-23
Abstract: Seal assemblies are provided, comprising a seal holder (110) including a cylindrical wall portion (112) having a tapered distal portion (114), wherein the cylindrical wall portion defines a central passage. The seal assembly comprises a ball seal (120) supported in the central passage of the seal holder. The ball seal includes a distal aperture (122) and a proximal aperture (124), wherein the distal and/or proximal aperture is dimensioned for substantial sealed reception with a surgical instrument. The ball seal is adapted for angular movement relative to a central longitudinal axis of the seal holder upon angulation of the surgical instrument, whereby the ball seal substantially maintains the seal with the surgical instrument. The seal assembly comprises a seal cover (130) defining an aperture (136) formed in a transverse wall (132) thereof. The seal cover is configured for connection with the seal holder for maintaining the ball seal within the central passage of the seal holder.
Patent EP-2143564-A1 (EP)
Inventor: PRZEMYSLAW GEBALA
IPC: B42C7/00
Filed: 2008-07-10
Abstract: The way of production books in hard covers with rounded corners in an example of it's realization is based on that the materials for a block is taken through the printing process ( 1 ), and afterwards laminating process ( 2 ), while in the producing the cover process ( 3 ) using spinning knives, in single sheets of laminated cover material one cuts in four edges profiles in three fingers shape and afterwards in the process of shaping the corners ( 4 ) using the machine one simultaneously bows down in the way of wrapping the profiles in the three fingers shape, one presses and finally form through the high temperature the rounded corners and the cover prepared in such way is being connected with the block through the hanging process ( 5 ). Before the hanging process ( 5 ) the materials for the block is taken through the printing process ( 6 ), and afterwards in sequence is taken through a process of folding ( 7 ), gathering ( 8 ), sewing ( 9 ), gluing (1 0 ) and cutting ( 11 ).
Patent EP-2121800-A1 (EP)
Inventor: BRENNER GABRIELE
IPC: C08G63/183
Filed: 2008-01-08
Abstract: Es wird die Herstellung von hochmolekularen, kristallinen Copolyestern mit guter Löslichkeit in nicht halogenierten und nicht aromatischen Lösungsmitteln und ihre Verwendung in Klebstoffen beschrieben.
Patent EP-2121342-A1 (EP)
Inventor: CHABUT FRANCOISE
IPC: B42D15/10
Filed: 2008-01-23
Abstract: La présente invention concerne la personnalisation de graphismes de documents d'identité. Le document d'identité comprend un corps où au moins une des principales surfaces forme une surface d'impression, sur laquelle le graphisme (14A, 14B) et/ou les informations personnalisées (24A, 24B) sont imprimées, ladite surface d'impression étant couverte avec un film protecteur renforcé (31A, 31B). Le document d'identité comprend en outre une couche protectrice (25A, 25B) transférée sur la surface d'impression par ruban encreur, ladite couche protectrice étant capable de permettre l'adhérence dudit film protecteur renforcé (31A, 31B) sur l'encre transférée à ladite surface d'impression.
Patent EP-2038122-A1 (EP)
Inventor: FUJII KAORI
IPC: B41J2/045
Filed: 2008-02-04
Abstract: L'invention concerne une tête à jet de liquide qui comprend un élément de buse ayant plusieurs buses pour projeter un liquide à partir de celles-ci, un élément de trajet d'écoulement formant au moins une partie d'une chambre de liquide communiquant avec chacune des différentes buses, et une partie de génération de pression pour générer une pression qui est appliquée au liquide à l'intérieur de la chambre de liquide. L'élément de buse et l'élément de trajet d'écoulement sont chacun formés par un matériau métallique. Le matériau métallique de l'élément de buse a sensiblement la même composition que le matériau métallique de l'élément de trajet d'écoulement. Le matériau métallique de l'élément de buse comprend des particules cristallines ayant un diamètre moyen de particule qui est inférieur à celui des particules cristallines comprises dans le matériau métallique de l'élément de trajet d'écoulement.
Patent EP-2132165-A1 (EP)
Inventor: OFTRING ALFRED
IPC: C07C211/48
Filed: 2008-02-28
Abstract: The invention relates to a method for producing ethylenediamine, by hydrogenation of aminoacetonitrile on a catalyst, characterised in that the hydrogenation is carried out in solution, containing aminoacetonitrile, water with a fraction of 0 to 60 wt. % and a solvent, wherein the aminoacetonitrile in the solution is added to the reaction vessel at a rate which is not greater than the rate with which the aminoacetonitrile reacts with hydrogen in the hydrogenation.
Patent EP-2255495-A1 (EP)
Title: Prédiction de localisation de systèmes à l'intérieur d'un centre de données à l'aide de coefficients de corrélation
Inventor: LUGO WILFREDO E
IPC: H04L12/28
Filed: 2008-03-06
Abstract: La présente invention permet une prédiction de localisation d'un système dans un centre de données. De manière spécifique, l'invention surveille des ressources provenant des systèmes dans le centre de données et des points de mesure dans le centre de données. Une ressource de système surveille les conditions internes du système. Un point de mesure de centre de données est n'importe quel dispositif qui fournit des informations d'environnement ou de ressources de centre de données du centre de données. Les conditions obtenues à partir des ressources de système et des points de mesure sont corrélées, puis utilisées pour prédire l'emplacement du système dans le centre de données. Par exemple, par la corrélation de valeurs de détecteur de chaleur et de mesures de bande passante, le mécanisme de prédiction peut être apte à prédire qu'un système qui a une pointe d'utilisation de réseau et qui est à pleine capacité est proche de points de mesure qui ont détecté une valeur de détecteur de chaleur accrue et détecté une utilisation de bande passante accrue en même temps que la machine a eu sa pointe d'utilisation de réseau.
Patent EP-2118375-A1 (EP)
Title: Système de commande pour tambour à lame
Inventor: PARKER CARL D
IPC: E01C23/088
Filed: 2008-01-18
Abstract: La présente invention concerne un véhicule de travail comportant un moteur et une transmission engageant de façon opérationnelle le moteur. La transmission a au moins un arbre d'entrée et au moins un arbre de sortie dont un taux d'une vitesse de rotation de l'arbre de sortie par rapport à une vitesse de rotation de l'arbre d'entrée peut être modifié par ladite transmission. Le véhicule de travail comporte en outre un tambour à lame engageant de façon opérationnelle ladite transmission et un dispositif de commande, ledit dispositif de commande sélectionnant le taux de transmission en fonction d'une saisie d'un utilisateur du véhicule de travail.
Patent EP-2126287-A1 (EP)
Inventor: MALTSON JOHN DAVID
IPC: F01D5/18
Filed: 2008-03-27
Abstract: A flow channel with a branch channel (5, 16, 21) substantially perpendicular to a main channel (7, 15, 20), comprising an edge defining an inlet opening of the branch channel, is provided which is characterised by a chamfer (13) at the upstream edge (10) of the inlet opening and a sharp downstream edge (11) of the inlet opening for effective use of cross flow under suppression of turbulences (12).
Patent EP-2139666-A1 (EP)
Inventor: NG KHENG JOO
IPC: B29C49/42
Filed: 2008-04-22
Abstract: A preform transfer device includes at least one clamp including two levers pivoting between an open position and a closed position and elements for the elastic return of the levers to the closed position. The device includes a mechanism for selectively controlling the opening and closing of the clamp, this mechanism including: a lever spreading member driven by a link including at least one free end able to interact with actuating elements to cause the clamp to open against the force of the elastic return elements, and associated locking elements that are able to move between a locked position in which the clamp is held in the open position and a retracted position in which the clamp is free to close, the locking elements being able to interact with second actuating elements designed to cause the locking element to move from the locked position to the retracted position, to trigger the closure of the clamp.
Patent EP-2167529-A1 (EP)
Inventor: SINCLAIR JOHN CHARLES
IPC: C07K14/47
Filed: 2008-04-23
Abstract: Protein layers 1 repeating regularly in two dimensions comprise protein protomers 2 which each comprise at least two monomers 5, 6 genetically fused together. The monomers 5, 6 are monomers of respective oligomer assemblies 3, 4 into which the monomers are assembled to assembly of the protein layer. The first oligomer assembly 3 belongs to a dihedral point group of order O, where O equals 3, 4 or 6 and has a set of O rotational symmetry axes of order 2. The second oligomer assembly 4 has a rotational symmetry axis of order 2. Due to the symmetry of the oligomer assemblies 3, 4, the rotational symmetry axes of each second oligomer assembly 4 is aligned with one of said set of O rotational symmetry axes of a first oligomer assembly 3 with 2 protomers being arranged symmetrically therearound. Thus, an 2-fold fusion between the oligomer assemblies 3, 4 is produced and the arrangements of the rotational symmetry axes of the oligomer assemblies 3, 4 cause the protein layer to repeat regularly. The protein layer has many uses, for example to support molecular entities for biosensing, x-ray crystallography or electron microscopy.
Patent EP-2132411-A1 (EP)
Inventor: MISTRY JIBAN JYOTI
IPC: F01C11/00
Filed: 2008-04-08
Abstract: A split-cycle variable capacity rotary spark ignition engine system having at least a first rotary configuration (Cl) including repetitively volume variable working chambers [60, 61, 62] for carrying out the combustion-expansion and exhaust phases and at least a second rotary configuration (C2) including repetitively volume variable working chambers (70, 71, 72) for carrying out the intake and compression phases of a four phase engine cycle. Dividing seal means (73, 74 of Cl, 75, 76 of C2) for periodically dividing each of successive working chambers into a volume enlarging leading portion and a volume contracting trailing portion. Discharge valve means for varying compression chamber capacity through discharging fraction of trapped intake gas from compression chambers. A first phase altering arrangement is provided for varying the phase relation between the first rotary configuration (Cl) and the second rotary configuration (C2). A second phase altering arrangement varies phase relation between the discharge valve means and corresponding compression chambers. The first rotary configuration (Cl) having variable capacity combustion chambers operatively synchronize with the variable capacity compression chambers of the second rotary configuration (C2) so that accomplish nearly full-load-like combustion environment through a substantially wide engine operating range.
Patent EP-2133330-A1 (EP)
Inventor: AOKI KAZUMASA
IPC: A61P13/12
Filed: 2008-04-08
Abstract: [Object] A prophylactic or therapeutic agent for a cardiovascular disease is provided. 
     [Means for Resolution] An atropisomer of a compound represented by the following general formula (I):
     
(wherein R 1  is a C1-C3 alkyl group or a hydroxy-C1-C3 alkyl group; and R 2  is a hydrogen atom or a C1-C3 alkoxy group).
Patent EP-2144739-A1 (EP)
Title: Panneau de vitrage plastique ayant un motif imprimé durcissable aux uv et procédé de fabrication de celui-ci
Inventor: LEFAUX CHRISTOPHE
IPC: B29C45/14
Filed: 2008-05-01
Abstract: L'invention concerne un procédé économique de fabrication d'un panneau de vitrage plastique ayant un marquage décoratif et/ou une bordure opaque imprimés à partir d'une encre durcissable aux UV. Ce procédé économique comprend les étapes de formation d'un panneau plastique ; d'impression d'un motif opaque à partir d'une encre, le motif ayant un côté A et un côté B, le côté B étant en contact avec le panneau plastique ; de durcissement de l'encre sous la forme du motif imprimé en utilisant un rayonnement UV dirigé sur l'encre à la fois à partir du côté A et du côté B ; d'application d'une couche résistante aux intempéries sur le côté B de l'encre et sur le panneau plastique ; de durcissement de la couche résistante aux intempéries ; et de dépôt d'une couche résistante à l'abrasion sur la couche résistante aux intempéries.
Patent EP-2217812-A1 (EP)
Inventor: KUEHBAUCH HEIKO
IPC: F15B13/08
Filed: 2008-04-15
Abstract: A valve arrangement (5) as well as a switchgear cubicle arrangement (1) that is equipped therewith are proposed. The valve arrangement (5) comprises a modular subassembly (18) consisting of several module elements (22) on which module element surfaces (38) are formed that jointly define a base (6). Several duct outlets (12) which are surrounded by a seal accommodating groove (35) are provided within the base (6). The seal accommodating groove (35) is composed of several longitudinal groove sections (42) of the individual module element surfaces (38), said longitudinal groove sections (42) extending into one another.
Patent EP-2165856-A1 (EP)
Inventor: KAJI SHINICHI
IPC: B60C11/11
Filed: 2008-05-08
Abstract: A pneumatic tire has a tread pattern having shoulder blocks arranged in a tire circumferential direction in a shoulder portion of a tread surface, and slits to sectionalize the shoulder blocks. Slit wall surfaces in a trailing side and a leading side of the shoulder blocks are inclined to the slit side from both end portions in a width direction of the shoulder block toward a center portion in the width direction. A notch portion is provided in the center portion in the width direction in the slit wall surface in the trailing side or the leading side of the shoulder block.
Patent EP-2149914-A1 (EP)
Inventor: SATOH MASAKAZU
IPC: H01L31/0216
Filed: 2008-05-19
Abstract: A light shield (204) for blocking light traveling toward a PIN photodiode (413) from a glass substrate (314) side is formed of a conductive material, and a reference electric potential (Vr - nVoc) equal to that of a cathode of the PIN photodiode (413) is applied to the light shield (204) from a power supply circuit (266). Thus, inductive noise for a photoelectric conversion device used for an ambient light sensor is further reduced in a display device.
Patent EP-2130196-A1 (EP)
Inventor: MERCIER-GALLAY AMBROISE
IPC: G09F3/16
Filed: 2008-02-11
Abstract: The low-voltage electric apparatus with at least one labelling position (3) as per the invention has an insulating body (2) comprising the labelling position (3), numbering at least one, said position (3) including fastening means (6) for a labelling element (4). The labelling position (3) includes a marking zone (5) located in relation to the outside of the insulating body (2) to the front or substantially at the same level as the most advanced portion of the fastening means (6).
Patent EP-2139365-A1 (EP)
Inventor: MALENOTTI FABIO
IPC: A47C1/032
Filed: 2008-06-05
Abstract: A chair with backrest that can be inclined backwards has a seat carried by a support (2b), connected by means of an articulated-parallelogram system (11, 12) to the fixed supporting structure (4, 10) of the chair. The support (17) of the backrest is articulated to the support (2b) of the seat and is operatively connected to said articulated-parallelogram system so that any reclining backwards of the backrest causes a raising and a slight inclination backwards of the seat. The support of the backrest (17) is moreover connected by means of an articulated arm (23) to a sliding support (2a), on which the seat is mounted (2), and is in turn mounted so that it can slide in a longitudinal direction (A) on seat support (2b).
Patent EP-2168219-A1 (EP)
Title: Traversée électrique
Inventor: STOLT LARS
IPC: H01B17/30
Filed: 2008-06-05
Abstract: La présente invention concerne une traversée électrique (200) destinée à effectuer une connexion électrique durable et fiable à travers une paroi (227) d'une chambre à vide (225). La traversée électrique (200) comprend un élément tubulaire ayant une extrémité ouverte (217) et une extrémité fermée (219). Au moins un conducteur (201) s'étend dans l'extrémité fermée (217) et est fixé sur celle-ci par un joint d'étanchéité sous vide (214). Le joint (214) est disposé afin de ne pas être dans la ligne visuelle de l'extrémité ouverte (217). Ainsi, les éléments projetés (220) et le rayonnement thermique direct (221) ne peuvent atteindre directement le joint (214), étendant ainsi la durée nécessaire pour que la contamination du joint (214) provoque des problèmes.
Patent EP-2144930-A1 (EP)
Title: Fc à chaîne simple, procédés de fabrication et procédés de traitement
Inventor: MOORE MARGARET D
IPC: A61P35/00
Filed: 2008-04-18
Abstract: La présente invention concerne de manière générale des molécules scFc. Les molécules scFc comprennent au moins deux régions Fc et au moins un lieur, et peuvent être obtenues dans une variété de configurations à chaîne simple. Les molécules scFc peuvent également comprendre au moins une entité de liaison et/ou au moins une molécule fonctionnelle. Les entités de liaison peuvent être fusionnées à la molécule scFc selon une variété de configurations. En outre, la présente invention se rapporte généralement à des procédés de fabrication de telles molécules et leurs procédés d'utilisation. Les molécules scFc susmentionnées peuvent être produites de manière recombinée. L'invention a également trait à des formes monovalentes de molécules scFc qui présentent une réponse ADCC et/ou CDC supérieure ou égale à celle de molécules bivalentes ciblant les mêmes antigènes. L'invention se rapporte à des compositions de liaison d'antigènes améliorées. L'invention a aussi pour objet des procédés d'utilisation des molécules scFc de la présente invention.
Patent EP-2173467-A1 (EP)
Inventor: RONAGHI MOSTAFA
IPC: B01J19/00
Filed: 2008-07-10
Abstract: L'invention concerne un procédé et un appareil qui utilise un champ électrique pour des dosages biologiques améliorés. Le champ électrique est appliqué aux bornes d'un dispositif ayant des puits, qui reçoivent des réactifs, qui portent une charge. Le dispositif utilise ainsi une source de tension contrôlable entre les première et seconde électrodes, qui est contrôlable pour fournir une charge positive et une charge négative à une électrode donnée. Par une utilisation contrôlée du champ électrique, des espèces chargées dans un fluide situé dans un canal de fluide sont dirigées vers l'intérieur ou l'extérieur du puits par un champ électrique entre les électrodes. Le présent procédé implique le transport de fluide, comme dans un dispositif microfluidique et le mouvement induit par champ électrique d'espèces réactives selon diverses procédures de dosage, telles que le séquençage d'ADN, la synthèse d'ADN ou similaire.
Patent EP-2183206-A1 (EP)
Inventor: DAWIDOWSKI DIRK
IPC: C07C29/70
Filed: 2008-07-31
Abstract: The present invention relates to a process for the preparation of lithium alcoholate solutions (formula I).