Patent SG-11201809577Y-A (SG)
Title: Laser ablation machine for labeling cryorenically-frozen vials
Inventor: BREHM ANDY
IPC: B41M5/24
Filed: 2017-04-27
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 111111101111 0 DOI 010111110101111 0 111 011111011111111011111110111110110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date ......0\" WO 2017/189848 Al 02 November 2017 (02.11.2017) W I PO I PCT (51) International Patent Classification: CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, AO1N 1/02 (2006.01) B41M 5/24 (2006.01) DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (21) International Application Number: HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, PCT/US2017/029840 KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, (22) International Filing Date: PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, 27 April 2017 (27.04.2017) SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (25) Filing Language: English (26) Publication Language: English (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (30) Priority Data: GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, 62/330,071 30 April 2016 (30.04.2016) US UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, (71) Applicant: MERIAL, INC. [US/US]; 3239 Satellite Blvd., EE, ES, FL FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, Duluth, Georgia 30096 (US). MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, (72) Inventors: BREHM, Andy; 887 Carruth Road, Jeffer- TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, son, Georgia 30549 (US). FREEMAN, Dennis, Jerome; KM, ML, MR, NE, SN, TD, TG). 2463 Lothridge Road, Cleveland, Georgia 30528 (US). SCHINDLER, Ed; 2952 Emerson Lake Drive, Snellville, Published: _ Georgia 30078 (US). CAMPBELL, Julie; 710 Park Av- — with international search report (Art. 21(3)) — enue, Baldwin, Georgia 30511 (US). = (74) Agent: JARECKI-BLACK, Judy; 3239 Satellite Blvd., = Duluth, Georgia 30096 (US). (81) Designated States (unless otherwise indicated, for every = kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, — _ (54) Title: = _= FIG.1 = = = = = = _ _ = 1-1 GC 71' GC GC Il Ir ---- Il ei BOO \ al I T , LASER '10 fir 219 ..„ i , 100 ABLATION 220 /18 426 201 427 '00 / 408 - 14 MACHINE 41 FOR *1 s LABELING CRYORENICALLY-FROZEN VIALS (57) : The invention relates to a machine for labeling \"blank-labeled\" cryogenically-frozen vials or ampoules, which contain heat-labile biological materials, and to which a laser-light sensitive material had been applied prior to freezing. Accordingly, the machine has been designed to maintain the integrity of the biological materials throughout all phases of the labeling process. The machine generally comprises a master control system; a programmable user interface; a frame; cryogenic freezer assemblies, for keeping the vials at the required low temperatures; an infeed assembly, configured to receive and po- sition blank-labeled cryogenic vials; a cryostatic labeling/quality control tun- nel, wherein the vials are maintained at the required temperature, labeled by laser ablation, and checked for quality; and, an outfeed assembly. The machine further comprises a means for transporting the vials from the infeed assem- bly to the tunnel, and from the tunnel to the outfeed assembly. Vials labeled according to the instant disclosure are ultimately manually or automatically loaded into cryogenic shipping containers. '101 C