baber/WOPTO huggingface dataset:
Patent CA-2569242-A1 (CA)
Title: Improved cardiomyocyte differentiation
Inventor: MUMMERY CHRISTINE LINDSAY
IPC: C12N5/077
Filed: 2004-06-01
Abstract: The present invention provides a method of enhancing the efficiency of differentiation of hES cells into cardiomyocytes which method comprises incubating the cells under serem free conditions. The method typically includes providing cells that induce cardiomyocyte differentiation by cell to cell contact. Differentiation to cardiomyocytes can occur via two routes, namely by spontaneous differentiation and by induced differentiation. Without wishing to be bound by theory, the present inventors hypthesise that, in the case of induced differentiation, END-2 cells, for instance, are needed for aggregation to cause local high cell densities and in inducing differentation of nascent mesodern. This second step could be enhanced in any human embryonic stem cell line leading to the prediction that it will work in lines other than hES. In cell lines that undergo sponantaneous differentiation, it is hypothesised that local induction of embryoid bodies in edoderm occurs.  Typically for induced differentiation this method will also comprise culturing the hES cell with a cell excreting at least one cardiomyocyte differentiation inducing factor or with an extracellular medium therefrom, under conditions that induce differentiation.
Patent CA-2570750-A1 (CA)
Inventor: NONGPIUR RAJEEV
IPC: G10L21/00
Filed: 2006-12-11
Abstract: A system extends the bandwidth of a narrowband speech signal into a wideband spectrum. The system includes a high-band generator that generates a high frequency spectrum based on a narrowband spectrum. A background noise generator generates a high frequency background noise spectrum based on a background noise within the narrowband spectrum. A summing circuit linked to the high-band generator and the background noise generator combines the high frequency spectrum and narrowband spectrum and the high frequency background noise spectrum.
Patent CA-2571569-A1 (CA)
Title: Use of targeted oxidative therapeutic formulation in endodontic treatment
Inventor: HOFMANN ROBERT F
IPC: A61K31/327
Filed: 2005-06-22
Abstract: A pharmaceutical formulation and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as dimethylsulfoxide ("DMSO"); a dye containing a chelated metal, such as hematoporphyrin; and an aromatic redox compound, such as benzoquinone. The pharmaceutical formulation is used effectively to stimulate periapical bone regeneration and for the endodontic treatment of periapical bone abscess, and fibromas, in a patient.
Patent CA-2571917-A1 (CA)
Inventor: POMPEJUS MARKUS
IPC: C07K14/34
Filed: 2000-12-22
Abstract: Isolated nucleic acid molecules, designated MP nucleic acid molecules, which encode novel MP proteins form Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MP proteins, mutated MP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MP genes in this organism.
Patent CA-2573421-A1 (CA)
Inventor: WEPFER BENJAMIN
IPC: F41H11/02
Filed: 2007-01-09
Abstract: The Missile Approach Warning Sensor Test apparatus, MAWST, serves to test the operability of a missile-approach warning system, MAWS, operating in the solar-blind UV-C range and/or in the IR range. The system, which finds application in military and civilian aircraft, vehicles, and ships, reacts to the radiation emission of an approaching guided missile and triggers protective measures. The test-apparatus stimulates the MAWS by means of a simulated radiation emission. The test apparatus contains the following components: a UVC-LED which emits UV light in the range of 240 to 290 nm and a controller which activates at least the UVC-LED so that it simulates an emission profile of a guided missile.
Patent CA-2574600-A1 (CA)
Title: Pyridine derivatives
Inventor: MAW GRAHAM NIGEL
IPC: A61P29/00
Filed: 2005-07-12
Abstract: The present invention relates to compounds of the formula (I) and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds for the treatment of pain.
Patent CA-2574877-A1 (CA)
Title: Improved ammonia plant
Inventor: REDDY SATISH
IPC: C01C1/00
Filed: 2005-07-28
Abstract: A synthesis plant (309A) includes a compression device (360A) that increases a pressure differential between the bottom product pressure of a cryogenic separator (340A) and the delivery pressure of the bottom product to a downstream plant component. Such increased pressure differential is employed to increase cooling in the separator (340A) to thereby significantly reduce the volume of excess air. In most preferred aspects, at least part of the energy required for the compression device is provided by expansion (320A) of the separator feed.
Patent CA-2576470-A1 (CA)
Title: Electronic lockouts and surgical instrument including same
Inventor: TIMPERMAN EUGENE L
IPC: A61B17/068
Filed: 2007-01-30
Abstract: A surgical cutting and stapling instrument is disclosed. The instrument includes an end effector and a handle. The end effector includes a channel, an anvil pivotally attached to the channel, a moveable cutting instrument for cutting an object positioned between the anvil and the channel, and a staple cartridge configured for removable receipt by the channel. The staple cartridge includes a sled that is engaged by the cutting instrument during a cutting stoke. The handle includes a motor for actuating the cutting instrument via a main drive shaft assembly.  The instrument further includes a first interlock circuit for enabling initiation of motor operation based upon a position of the staple cartridge.
Patent CA-2577719-A1 (CA)
Title: Determination of hemodynamic parameters
Inventor: LEE TING Y
IPC: A61B5/00
Filed: 2005-08-22
Abstract: Hemodynamic parameters of an organ are determined by first estimating hemodynamic parameters for portions of an organ from time sequenced images of the portions obtained after injection of a contrast agent. For each of the portions, the accuracy of the estimated hemodynamic parameters is assessed based on at least one of (i) a relationship between extraction efficiency product (FE) and contrast distribution volume in interstitial space (Ve); (ii) a relationship between blood plasma space volume (Vp), FE, and Ve; and (iii) a value of contrast distribution volume (VD).
Patent CA-2578407-A1 (CA)
Inventor: PARKER MICHAEL H
IPC: C07D307/81
Filed: 2005-08-22
Abstract: The present invention is directed to novel benzo-fused heteroaryl sulfamide derivatives, pharmaceutical compositions containing them and their use in the treatment of epilepsy and related disorders.
Patent CA-2579885-A1 (CA)
Title: Association of protein polymorphisms with coronary heart disease
Inventor: GOEGELEIN HEINZ
IPC: C12Q1/68
Filed: 2005-08-27
Abstract: The invention concerns methods of identifying an increase in risk for coronary heart disease in an individual, wherein the presence of another amino acid than Glutaminic Acid at position 23 and/ or the presence of another amino acid than Valine at position 337 in the Kir6.2 protein is determined in a sample. Moreover, probes, primers, polypeptides or polynucleotides suitable for said methods are claimed.
Patent CA-2582609-A1 (CA)
Title: Tube coupling for tube elements
Inventor: STOETZER ERWIN
IPC: F16L21/00
Filed: 2007-03-21
Abstract: The invention relates to a tube coupling for tube elements comprising a socket and a plug which can be inserted axially into the socket. The tube coupling has a joining portion for producing a torque proof junction between socket and plug as well as a securing portion for securing the axial position of the plug in the socket. The securing of the axial position is brought about by two corresponding annular grooves, into which at least one locking element can be inserted via an insertion opening in order to produce a form-locking connection. To secure the locking element a plurality of radial bores is provided on the inner annular groove, into which a securing bolt can be inserted.
Patent CA-2583291-A1 (CA)
Title: Appareil et procede d'accrochage ameliores
Inventor: HOWLETT PAUL
IPC: E21B43/10
Filed: 2005-10-10
Abstract: La présente invention concerne un appareil, tel qu'un revêtement, destiné à être accroché dans un tubulaire de fond de puits, tel qu'un cuvelage. L'appareil comprend une ou plusieurs parties abrasives réparties sur la circonférence, agencées pour être déplacées radialement vers l'extérieur par une unité de formation de dépressions ou un agrandisseur. Dans un mode de réalisation, les parties abrasives sont prévues sur des disques (21) déplaçables dans des évidements (20) situés dans le diamètre extérieur (19) de l'appareil accroché. Dans un mode de réalisation, l'appareil est accroché par actionnement d'une unité de formation de dépressions prévue sur l'outil en fonctionnement.
Patent CA-2584069-A1 (CA)
Inventor: MARGOLIN ALEXEY L
IPC: A61K38/46
Filed: 2005-10-14
Abstract: The present invention relates to compositions for the treatment of conditions, including pancreatic insufficiency. The compositions of the present invention comprise lipase, protease and amylase in a particular ratio that provides beneficial results in patients, such as those afflicted with pancreatic insufficiency. This invention also relates to methods using such compositions for the treatment of pancreatic insufficiency.
Patent CA-2585046-A1 (CA)
Title: Dynamic efficiency optimization of piezoelectric actuator
Inventor: HILDEBRANDT EDWIN I
IPC: E21B47/12
Filed: 2007-04-10
Abstract: This invention applies to the means whereby capacitance changes due to varying temperature and/or pressure in a piezoelectric transducer used for acoustic telemetry in a drilling environment is dynamically offset by modifying one or more parameters associated with the drive or control circuitry of said transducer. The object of the invention is to closely maintain the transducer in a resonant mode, thereby ensuring optimum energy consumption.
Patent CA-2587991-A1 (CA)
Title: Method and apparatus for dispensing diagnostic test strips
Inventor: LOVELL JOHN
IPC: G01N37/00
Filed: 2007-05-08
Abstract: An apparatus for storing and dispensing a test strip includes a container configured to store a radial array of test strips. The container maintains appropriate environmental conditions, such as humidity, for storing the test strips. The container has a plurality of radially extending slots formed by a plurality of dividing walls, and each slot is sized to receive a single test strip. A rotatably positionable cover is carried by the container for covering the plurality of radially extending slots. The cover includes an opening, which, when the cover rotates, aligns with one of the slots at a time to allow removal of a single test strip located within the respective slot. Accordingly, the unused test strips remain free of contaminants such as naturally occurring skin oils on a user's hand.
Patent CA-2588753-A1 (CA)
Title: Cartouche unitaire pour traitement de particules
Inventor: BEAUPRE DEREK
IPC: G01N15/00
Filed: 2005-12-05
Abstract: L'invention porte sur une cartouche jetable unique permettant de réaliser une opération sur une particule, tel que le tri de la particule, dans laquelle sont encapsulées toutes les surfaces de contact avec les liquides, laquelle cartouche est utilisée dans les techniques du traitement microfluidique des particules. La cartouche de l'invention est mise en interface avec un système d'exploitation afin d'effectuer le traitement des particules. L'encapsulation des surfaces de contact avec les liquides garantit, améliore ou favorise l'isolement de l'opérateur et/ou l'isolement du produit. La cartouche peut être utilisée avec n'importe quelle technique adaptée au traitement des particules.
Patent CA-2590898-A1 (CA)
Title: 3,4,(5)-substituted tetrahvdropyridines
Inventor: KANAZAWA TAKANORI
IPC: C07D211/78
Filed: 2006-01-12
Abstract: Organic Compounds 3,4(,5)-substituted tetrahydropyridine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4(,5)- substituted tetrahydropyridine compound, and/or a method of treatment comprising administering a 3,4(,5)-substituted tetrahydropyridine compound, a method for the manufacture of a 3,4(,5)- substituted tetrahydropyridine compound, and novel intermediates and partial steps for its synthesis. The 3,4(,5)- substituted tetrahydropyridine compounds have the formula I wherein the substituents and symbols are as described in the specification.
Patent CA-2591864-A1 (CA)
Inventor: HERRERA TABOADA LIDCAY
IPC: C08G73/02
Filed: 2006-01-24
Abstract: The invention relates to the use of water-soluble or water-dispersible polymers as additives for detergents. Said polymers can be obtained by the reaction of (a) polyalkylene polyamines, polyamidoamines or polyamidoamines grafted with ethylene imine, or mixtures of said compounds, (b) as desired at least bifunctional cross-linking agents, and (c) monoethylenically unsaturated carboxylic acids, salts, esters, amides or nitriles of monoethylenically unsaturated carboxylic acids, chlorocarboxylic acids and/or glycidyl compounds, the constituents (a) having an average molecular weight Mw of between 20 000 and 2 000 000, and the molar ratio of the hydrogen atoms on the nitrogen in constituent (a) to constituent (b) being between 1: 0.7 and 1: 0.9.
Patent CA-2595811-A1 (CA)
Title: Photoreceptor
Inventor: MAYO JAMES D
IPC: G03G5/047
Filed: 2007-08-01
Abstract: An electrophotographic imaging member includes a substrate, a photogenerating layer, and an optional overcoating layer, where the photogenerating layer includes a chemically functionalized carbon nanotube material.
Patent CA-2598802-A1 (CA)
Inventor: LERNER MATTHEW R
IPC: G06F11/00
Filed: 2005-07-28
Abstract: An operating system program launch menu, such as Start menu, provides various mechanisms for a user to quickly and efficiently locate and launch desired data items such as programs, data files, storage locations, and the like. A  search box within the program launch menu may be used to quickly locate programs, documents, communications, and other data items. An auto-complete feature may be used, e.g., when the user restricts the locations searched for the user-entered search text. A most commonly used program list may include programs based on various criteria including both frequency of use and recent use, thereby always including a most recently used item. An all programs view may display programs and documents in a hosted-tree view within the original confines of the program launch menu, thereby negating the need to open sub-menus on top of a large portion of the desktop displayed on the display device.
Patent CA-2599701-A1 (CA)
Title: Method and apparatus for a front access removable agitator motor
Inventor: GOFF DAVID
IPC: F25C1/00
Filed: 2005-11-28
Abstract: An agitator motor assembly is removable from a front of an ice dispenser for servicing, thereby eliminating the need to gain entrance into a storage bin to uncouple the agitator motor assembly from an agitator bar assembly. The ice dispenser includes the storage bin having a port, the agitator bar assembly disposed within the storage bin, and the agitator motor assembly mounted to a front of an exterior portion of the bin. A shaft of the agitator motor assembly engages the agitator bar assembly through the port, such that the agitator motor assembly rotates the agitator bar assembly when powered. The agitator motor assembly further includes a fastening device that passes through a bore in the shaft and engages the agitator bar assembly, thereby coupling the agitator motor assembly to the agitator bar assembly. A method for removing the agitator motor assembly is also provided.
Patent CA-2599829-A1 (CA)
Title: Remote control system for a hearing aid
Inventor: TOPHOLM JULIAN
IPC: H04R25/00
Filed: 2005-03-18
Abstract: A remote control system for a hearing aid comprises a hearing aid (9), a mobile telephone (1) and a plug-in device (5). The mobile telephone (1) is executing hearing aid remote control software and transmitting commands to the hearing aid (9) via the plug-in device (5). The plug-in device (5) comprises means for transmitting remote control commands or audio to the hearing aid (9) wirelessly. The invention provides a system, a plug-in device and a mobile telephone.
Patent CA-2600070-A1 (CA)
Title: Method and system for controlling a construction machine
Inventor: BISCONTIN RETO
IPC: E01C19/00
Filed: 2006-03-03
Abstract: The invention relates to a method for controlling slip form pavers. According to said method, the positions of two reflectors arranged on the longitudinal carriers of a machine frame are determined by means of measuring devices for determining positions, especially tachometers, arranged at defined points in a reference area. The positions of four points on the slip form pavers or the slip form paver plank in the reference area are determined from the position information and measurement by means of two gradient sensors arranged on the machine frame. The slip form paver, and thus the mounting height and position of the plank which is arranged in a defined manner in relation to the slip form paver, are automatically controlled by a comparison of the determined actual positions of the four points with the nominal positions thereof.
Patent CA-2601957-A1 (CA)
Inventor: BRAY WINDAL SCOTT
IPC: C04B24/04
Filed: 2007-09-17
Abstract: Set retarders of copolymers of at least one polymerizable ethylenically unsaturated monomer and at least one alkoxylated sulfate, phosphate or ketonic salt are capable of delaying the hardening of a cementitious slurry when introduced into a subterranean formation until a downhole temperature greater than or equal to 500° F is obtained, even in the absence of an intensifier. The ethylenically unsaturated monomer is preferably a carboxylic acid, amido carboxylic acid, carboxylic acid ester, amido carboxylic acid ester, hydroxylated alkyl ester of a carboxylic acid or a hydroxylated amido carboxylic acid ester, sulfonic acid, phosphonic acid or amide as well as mixtures thereof and the alkoxylated sulfate, phosphate or ketonic salt is of the formula:   (See above formula) wherein unit R1 is H or a C1-C4 alkyl; R2 is -(CH2CH2-O-)n or (-CH2CHCH3-O-)n or a mixture thereof; n ranges from about 1 to about 100; X is an anionic radical selected from -SO3, -PO3 or -COO or a water soluble cationic moiety which counterbalances the valence of the anionic radical X.
Patent CA-2606626-A1 (CA)
Inventor: JACQUES ALAIN
IPC: C11D3/37
Filed: 2006-04-27
Abstract: A fabric softener composition comprising: (a) from 0.01% to 50% by weight of a cationic or non-ionic softening compound; (b) at least 0.001%, by weight, of a water dispersible cross-linked cationic polymer derived from the polymerization of from 5 to 100 mole percent of a cationic vinyl addition monomer, from 0 to 95 mole percent of acrylamide, and from 5 to 500 ppm of a difunctional vinyl addition monomer cross-linking agent; and (c) an effective amount of at least one fabric or skin beneficiating ingredient contained within a microcapsule, the capsule shell comprising urea-formaldehyde or melamine-formaldehyde polymer and a second polymer comprising a polymer or copolymer of one or more anhydrides.
Patent CA-2606747-A1 (CA)
Title: The use of fatty acid alkoxylates as a method to remedy engine intake valve sticking
Inventor: VILARDO JONATHAN S
IPC: C10L1/14
Filed: 2006-05-10
Abstract: The use of alkoxylates and nitrogen containing detergents in a fuel additive composition to prevent intake valve sticking and reduce intake valve deposits.
Patent CA-2611118-A1 (CA)
Inventor: FRATER ROBERT HENRY
IPC: G10L21/02
Filed: 2006-06-07
Abstract: A digital playback device and a method and apparatus for modifying a digital audio signal. The method includes allowing a user to select a digital audio track and modifying the digital audio track with a predetermined spectral modification signal to create a spectrally modified digital audio track. The spectrally modified digital audio track can then be retrieved by a user to a digital playback device.
Patent CA-2612410-A1 (CA)
Inventor: CROCKFORD DAVID
IPC: A61K38/08
Filed: 2006-06-19
Abstract: A composition including a peptide agent including amino acid sequence LKKTET  or LKKTNT, a conservative variant thereof, or a stimulating agent that stimulates production of an LKKTET or LKKTNT peptide, or a conservative variant thereof, the composition including at least one amino acid stabilizing agent or lyophilization bulking agent, the composition being in lyophilized form, or in a form capable of being lyophilized.
Patent CA-2612676-A1 (CA)
Inventor: YONEYAMA TADAYUKI
IPC: F02M37/00
Filed: 2006-06-21
Abstract: A fuel feeder of an engine, comprising a gas-liquid separating device separating oil mist produced in an engine case from air by a labyrinth. An automatic fuel valve is operated by the pressure pulsation of the air from which the oil mist is separated by the gas-liquid separating device.  Accordingly, the automatic fuel valve can be prevented from being improperly operated due to the stagnation of oil therein by minimizing the entry of the oil mist into the automatic fuel valve. Furthermore, a breather passage for feeding the air from which the oil mist is separated by the gas-liquid separating device to a breather device is allowed to communicate with the automatic fuel valve through a negative pressure tube. As a result, a special passage for transmitting the pressure pulsation of the air in the engine case to the automatic fuel valve must not be installed in the fuel feeder.
Patent CA-2613067-A1 (CA)
Inventor: WOJTOWICZ ANDREW
IPC: A63F3/06
Filed: 2007-11-20
Abstract: A lottery ticket has a covering scratch-off coating applied over at least part of a game area, including game data applied over an ink layer including a lily pad. A detectable taggant additive material is admixed in an ink of the ink layer having the characteristic of being detectable by a detection scanner when applied over the substrate where the covering scratch-off coating masks the ability of the detection scanner to detect the detectable taggant additive material through the covering scratch-off coating. The scanning of the game area is used to detect areas where the scratch is removed in order to confirm that the game has been played or to detect patterns of removal in a probability type game.
Patent CA-2616454-A1 (CA)
Title: Station de distribution d'hydrogene et methode d'exploitation connexe
Inventor: COHEN JOSEPH PERRY
IPC: F17C5/00
Filed: 2007-12-28
Abstract: L'invention porte sur une station de distribution d'hydrogène et sur la méthode d'exploitation connexe pour faire le plein d'une multiplicité de récipients. Ladite station et sa méthode de distribution limitent la température des récipients à remplir lors de l'opération de plein. Les composants nécessaires à l'opération sont communs aux multiples points de distribution. La température du gaz du récipient à remplir peut être influencée par la commande de taux de montée en pression, le refroidissement de l'hydrogène dans un échangeur de chaleur et/ou l'utilisation d'un flux d'hydrogène à basse température.