baber/WOPTO huggingface dataset:
Patent EA-001206-B1 (EA)
Title: Process for preparing diketone compounds
Inventor: PEVERE VIRGINIE
IPC: B01J31/02
Filed: 1997-01-28
Abstract: 1. A process for the preparation of a compound of formula (I) by the reaction of a compound of formula (II) with a compound of formula (III), according to the reaction scheme indicated below:   wherein R1 is lower alkyl; R2 is lower alkyl; or phenyl optionally substituted by from one to five groups which may be the same or different selected from lower alkyl, lower haloalkyl, halogen and -SR4;  R3 is halogen, lower alkyl, lower haloalkyl, lower alkoxy, lower haloalkoxy, -S-alkyl, cycloalkyl having from 3 to 7 carbon atoms in the ring, alkenyl or alkynyl having from 3 to 7 carbon atoms, or -(CR5R6)q-SR2, wherein q is one or two;  R4 is lower alkyl; R5 and R6 independently represent hydrogen, lower alkyl or lower haloalkyl,  and n is zero or an integer from one to three, and wherein the reaction is performed with continuous distillation of the alcohol R1-OH formed in the course of the reaction, at atmospheric pressure or under reduced pressure, and where "lower" means radical, comprising at least one hydrocarbon chain. 2. A process according to claim 1 in which the reaction is performed in an aprotic solvent and at a temperature of from 0 degree C to the boiling point of the solvent, preferably between 0 degree C and 100 degree C.  3. A process according to claim 1 or 2 in the presence of a strong base, preferably an alkoxide of an alkali or alkaline earth metal or a metal hydride.  4. A process according to claim 1, 2 or 3, wherein the reaction is performed from 1 to 20% below atmospheric pressure.
Patent EA-006429-B1 (EA)
Title: Composition for preventing or restoring age-related functional deficits in mammals and method for use
Inventor: MALNOE ARMAND
IPC: A23L33/00
Filed: 2002-03-07
Abstract: The invention relates to a food composition intended to prevent or restore age-related functional deficits in mammals. The composition comprises at least one molecule that stimulates energy metabolism of the cell, selected from the group comprising L-carnitine, creatine, fatty acids, cardiolipin, nicotinamide or carbohydrate and at least and at least one antioxidant and is used for preparing a composition intended to be administered to a mammal. The use of the composition improves skeletal and cardiac muscle function, vascular function, cognitive function, vision, hearing, olfaction, skin and coat quality, bone and joint health, renal health, gut function, immune function, insulin sensitivity and inflammatory processes.
Patent EA-009082-B1 (EA)
Title: Ameliorant for chemical treatment of cancer
Inventor: KAGIYA TSUTOMU
IPC: A61P35/00
Filed: 2002-03-26
Abstract: Chromanol glycoside is 2-( alpha -D-glycopyranocyl)methyl-2,5,7,8-tetramethyl chroman-6-ol is proposed for use, represented by formula (3), as an ameliorating agent to enhance the carcinostatic activity of a carcinostatic substance for cancer chemotherapy and/or to inhibit side effects of the treatment. The ameliorant is novel and safe. It effectively functions even when used in a small amount in the chemical treatment of cancer.
Patent EA-008776-B1 (EA)
Title: Liquid stable composition of oxazaphosphorine with mesna
Inventor: DAFTARY GAUTAM VINOD
IPC: A61K31/724
Filed: 2003-09-04
Abstract: A low toxicity, stable oxazaphosphorine containing compositions with mesna for parenteral administration has been described. The process essentially requires addition of an oxazaphosphorine antineoplastic to the aqueous solution of an etherified β-cyclodextrin followed by addition of mesna as such or as an aqueous solution containing optionally, an etherified β-cyclodextrin. Preferably, the oxazaphosphorine antineoplastic is Ifosfamide and the etherified β-cyclodextrin is 2-hydroxypropyl-β-cyclodextrin.
Patent EA-008836-B1 (EA)
Title: Novel method of synthesising perindopril and the pharmaceutically-acceptable salts thereof
Inventor: DUBUFFET THIERRY
IPC: A61K38/00
Filed: 2004-06-28
Abstract: A method of synthesising perindopril having formula (I)and the pharmaceutically-acceptable salts thereof.
Patent EA-010086-B1 (EA)
Title: Expert system
Inventor: ALIEV TELMAN ABBAS OGLU
IPC: G06N3/02
Filed: 2006-02-21
Abstract: The present invention relates to medicine and concerns use of the information technologies in medicine specifically to the expert systems so-called the intellectual systems and intends for diagnosing and choosing the treatment and/or a surgical procedure in orthopedics, especially traumatic osteomyelitis. Essence of the invention provides that the expert system contains a user block (input/output information), an electronic card of a patient, a base of the medical histories, an AI block and an identikit block for the visualization of the disease focus. At the same time, the input of the electronic card connected to the input/output of the user block, to the input/output of the identikit block and to the output of the artificial intelligence block and to the input/output of the base of the medical histories, and the input/output of the artificial intelligence block connected to the input/output of the identikit block and to the input/output of the user block which connected to the input/output of the identikit block. The identikit block contains an artificial neural network of the heteroassociative type which consists of the neurons that are situated in the three layers. Along with the other known systems, the claimed diagnostic expert system is one of the solutions of the most important problem that modern medicine has: the development of the automated medical-diagnostic systems. Thus gathering, processing and displaying information can be considerably decreased and a period when an optimal choice for the quality process of a patient's treatment is made can also be reduced. Said system, having an appropriate database, can be used in surgery and traumatology.
Patent EA-014933-B1 (EA)
Title: Pesticidal compositions
Inventor: ZEUN RONALD
IPC: A01N51/00
Filed: 2006-05-02
Abstract: A method of controlling or preventing pathogenic damage or pest damage in a plant propagation material, a plant, parts of a plant and/or plant organs that grow at a later point in time, which comprises applying on the plant, part of the plant, or surroundings thereof, a pesticidal combination comprising, for example, at least three active ingredient components optionally together with one or more customary formulation auxiliaries, wherein component (I) is one or more of an -azole fungicide, component (II) is one or more of a phenylamide fungicide, component (III) is one or more of a phenylpyrrole fungicide, in any desired sequence or simultaneously.
Patent EA-014350-B1 (EA)
Title: Thiazole derivatives and use thereof
Inventor: QUATTROPANI ANNA
IPC: A61K31/427
Filed: 2006-05-24
Abstract: The present invention is related to thiazole derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
Patent EA-012063-B1 (EA)
Title: Multi-band transducer for multi-band feed horn
Inventor: SANDERS PHILIP
IPC: H01P1/161
Filed: 2006-01-31
Abstract: A multi-band transducer is described incorporating a coaxial waveguide interface for use with a multi-band feed and incorporating bent shaped probes yielding all-planar interfaces in microstrip for all frequency ranges and suitable for mass production. Hybrids can be incorporated for linear or circular polarization applications.
Patent EA-025395-B1 (EA)
Title: Core-1-POSITIVE MICROORGANISMS OR FRACTIONS THEREOF CAPABLE OF ACTIVATING CELLULAR IMMUNITY AGAINST CARBOHYDRATES
Inventor: GOLETZ STEFFEN
IPC: A61K39/00
Filed: 2007-11-12
Abstract: The present invention relates to the field of prevention and treatment of gastrointestinal disorders and tumors. More particularly, the present invention relates to the prevention and treatment of Core-1-positive carcinomas. The invention relates to Core-1-positive microorganisms and a method of producing the same and also to a method of prevention and treatment of Core-1 positive diseases using said microorganisms.
Patent EA-016015-B1 (EA)
Title: 4-(heterocyclyl)alkyl-n-(arylsulfonyl) indole compounds and their use as 5-htligands
Inventor: RAMAKRISHNA NIROGI VENKATA SATYA
IPC: A61K31/404
Filed: 2007-07-26
Abstract: The present invention relates to novel 4-(Heterocyclyl)alkyl-N- (arylsulfonyl)indole compounds of the formula (I), their derivatives, their stereoisomers, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, their derivatives, their stereoisomers, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. These compounds are useful in the treatment of various disorders that are related to 5-HTreceptor functions. Specifically, the compounds of this invention are also useful in the treatment of various CNS disorders, hematological disorders, eating disorders, diseases associated with pain, respiratory diseases, genito-urological disorders, cardiovascular diseases and cancer.
Patent EA-016442-B1 (EA)
Title: A method for conducting wellbore operation and method for stimulating reservoir formation while running a casing string into a wellbore
Inventor: CLARK BRIAN
IPC: E21B7/20
Filed: 2008-02-28
Abstract: A method for conducting wellbore operations in a well while running casing into the wellbore, the method comprising the steps of: connecting a stimulation assembly to a casing string; running the casing string into the wellbore; positioning the stimulation assembly at a selected reservoir formation; performing a stimulation operation at the reservoir formation; and running the casing string and stimulation assembly to the next desired position in the wellbore. A method for stimulating a reservoir formation while running a casing string into the wellbore, the method comprising the steps of: connecting a stimulation assembly to a casing string, the stimulation assembly including a packer actuator in operational connection with a packer and a logging sensor; running the casing string into the wellbore and positioning the logging assembly proximate to a selected reservoir formation; logging the reservoir formation; positioning the stimulation assembly proximate to the reservoir formation; actuating the packer to substantially isolate the reservoir formation from the wellbore; performing the stimulation operation; releasing the packers from sealing engagement with the wellbore; positioning the logging assembly proximate to the reservoir formation; logging the reservoir formation; and disconnecting the stimulation assembly from the casing string.
Patent EA-023887-B1 (EA)
Title: Foam formulation comprising a pickering emulsion
Inventor: DANIELS ROLF
IPC: A61Q19/00
Filed: 2008-05-09
Abstract: The invention relates to cosmetic and dermatologic foam formulations. The invention concerns a foam formulation comprising 0.5 wt.% or less of a conventional emulsifier or free of it. The claimed formulation comprises a Pickering emulsion stabilized by means of solid emulsifiers of the oil in water type, comprising an oil phase, a water phase and at least one thickening agent. The emulsion contains from 10 to 50 wt.% oil phase. The technical result consists in providing a formulation adapted for the formation of a stable foam upon dispensing of the formulation.
Patent EA-019158-B1 (EA)
Title: Plant for pulp cooling
Inventor: GRINEVICH ANATOLIJ VLADIMIROVICH
IPC: B01J19/00
Filed: 2011-03-15
Abstract: The invention relates to heat-exchanging plants for gas-liquid-solid systems and can be used mainly in production of extractive phosphoric acid for pulp cooling and also in chemical and other industries for carrying out other heat-mass-exchange processes. The plant comprises a vertical body with connection pipes for feeding pulp to be cooled and cooling gas, the vertical body is oval, the upper body part is additionally separated by a continuous vertical partition into two compartments to ratio (4-7):1, wherein lesser compartment has a connection pipe for feeding pressurized cooling gas, the greater compartment has a gas distributor, connection pipes for feeding pulp to be cooled and discharging heated gas to a reactor gas volume, the lower is deepened into pulp, the ratio of the gas volume height under the gas distributor to the body part deepened into the pulp is maintained within 1:(1,5-3) by changing the depth of body submersion into the pulp and changing the height of the gas distributor above the pulp working level in the reactor.
Patent EA-026488-B1 (EA)
Title: Conjugates of pyrrolo[1,4]benzodiazepine dimers as an anticancer agent
Inventor: COMMERCON ALAIN
IPC: C07D519/00
Filed: 2010-08-12
Abstract: The invention relates to novel conjugates of pyrrolo[1,4]benzodiazepine dimers which can be used as anticancer agents. Provided is a compound of formula (IA) or (IB)wherein the variants of radicals are stated in claim 1. Also provided are a process for the preparation of a conjugate based on the compound of formula (I), the conjugate and the solution of the conjugate obtained by said process. Further provided is the use of the compound of formula (I) in the preparation of a cell binding agent. Provided is the cell binding agent. Provided are a pharmaceutical composition for the preparation of an anticancer agent, comprising the compound of formula (I), and a pharmaceutical composition for the preparation of an anticancer agent, comprising said conjugate. Provided is the use of a compound of formula Por of a compound of formula(radicals are stated in claim 30) as an intermediate for the preparation of the compound of formula (I). Provided is the use of the compound of formula (I) and of the conjugate for the preparation of the anticancer agent.
Patent EA-023414-B1 (EA)
Title: Device for drilling a hole in a well tubular and for subsequent injection of a fluid or fluid mixture into an annular space or formation surrounding the well tubular, drill bit for said device and uses of said device
Inventor: BOEKHOLTZ EDO
IPC: E21B43/112
Filed: 2010-11-09
Abstract: A device for drilling a hole in a well tubular and for subsequent injection of a fluid or fluid mixture into an annular space or formation surrounding the well tubular comprises a housing and a drill bit assembly arranged inside the housing. In the drill bit assembly, a drill bit with cutting edges and grooves extending along its outside surface, is arranged. The device further comprises rotation means being capable of rotating the drill bit assembly and a fluid supply for supplying a fluid or fluid mixture to the grooves of the rotating drill bit. A seal surrounding the drill bit IS capable of sealing the device against the inner surface of the well tubular.
Patent EA-031999-B1 (EA)
Inventor: HIPSKIND JOHN
IPC: A23L11/00
Filed: 2011-12-09
Abstract: Соевые растения, содержащие событие SYHT0H2, способы его обнаружения и применения, и соевые растения, содержащие гетерологичную вставку в том же сайте, что и SYHT0H2.
Patent EA-027254-B1 (EA)
Title: Gelled food concentrate and process for preparation thereof
Inventor: POPP ALOIS KONRAD
IPC: A23L29/238
Filed: 2011-12-12
Abstract: A gelled food concentrate comprising a salt-sensitive gum, salt in an amount sufficient to keep the salt-sensitive gum in a salted-out state, a salt-stable gelling system in an amount effective to provide a gelled food concentrate, water, which gelled food concentrate, after dilution in an aqueous liquid, the aqueous liquid being water, can result in a ready-to-eat end product comprising: from 0.1 to 2.5 wt.% of salt and from 0.01 to 3.5 wt.% of a salt-sensitive gum, the ready-to-eat end product having a viscosity of higher than 15 mPa∙s at 20°C.
Patent EA-028647-B1 (EA)
Title: Anti-asic1 antibodies and uses thereof
Inventor: MACDONALD LYNN
IPC: C07K16/18
Filed: 2013-01-30
Abstract: The present invention provides antibodies and antigen-binding fragments thereof that specifically bind to cells expressing acid-sensing ion channel-1 (ASIC1). According to certain embodiments of the invention, the antibodies inhibit acid-induced, ASIC1-mediated ion currents in cells expressing human ASIC1. The antibodies of the invention are useful for the treatment of pain, including pain associated with surgical intervention and various diseases and disorders.
Patent EA-028234-B1 (EA)
Title: Locking-sealing device "granite"
Inventor: TEMBAEVA GULNARA ISAKHMETOVNA
IPC: E05B39/02
Filed: 2014-10-22
Abstract: The invention is related to devices for locking and simultaneous sealing of various facilities intended for transportation and/or storage of cargoes and valuable items, primarily at railway transport. The locking-and-sealing device comprises a body, a section of wire rope having one end secured in the body, and a spring-loaded fixing member including a roller. The body has coaxial inlet hole and outlet hole and a window with side surfaces communicating with the holes, the window having a strap inclined toward the inlet hole and disposed along the first side surface of the window, in the middle of its cross-section. The novel feature is that a second strap is provided that is disposed along the second side surface of the window and inclined toward the inlet hole. The first and second straps carry the fixing member in the form of an-shaped fork having two long and two short ribs embracing, on two sides, the first and the second inclined straps, respectively. Along the long ribs of the fork, symmetric slots are made accommodating a roller, and the hole between the short ribs of the fork accommodates a ball, the roller and the ball are adapted to rotate and to move longitudinally, respectively, in the symmetrical slots and in the fork hole, transversely to the axis of the inlet and outlet holes, and can interact, respectively, with the first and second inclined straps and with the outside surface of the free end of the wire rope section. On the side of the outlet hole, the fixing member carries a socket accommodating two protective plates adapted to interact with the socket, with the spring and with the outside surface of the free end of the wire rope section. The protective plates in the locking-and-sealing device are made in the form of ring segments, their concave side surface having a configuration following the outer profile of the wire rope section, and the outlet hole accommodates a protective washer rotatable in a plane transverse to the axis of symmetry of the inlet and outlet holes, the profile of the washer hole following the outer profile of the wire rope section. The technical results of the invention are: elimination of the possibility of criminal opening the locking-and-sealing device, in particular, by removal of the wire rope section from the device by "unscrewing"; reduction of a mechanical force required for drawing the wire rope section through the device as it is locked on the facility being sealed; and lower requirements for precision of making components for the device manufactured in mass production.
Patent EA-029873-B1 (EA)
Title: Prodrugs of fumarates and their use in treating various diseases
Inventor: ZEIDAN TAREK A
IPC: C07C309/18
Filed: 2014-03-14
Abstract: The present invention provides a compound of formula (III) and the use of said compound in a method of treating of a neurological disease.
Patent EA-030935-B1 (EA)
Title: Antiparasitic and pesticidal isoxazoline compounds
Inventor: MENG CHARLES Q
IPC: C07D413/12
Filed: 2014-10-30
Abstract: The present invention concerns novel isoxazoline compounds of formula (I) and salts thereof:wherein the variables D, D, D, D, D, R, B, B, B, R, R, R, R, R, Y, Z, L, a and b have the meanings as defined herein. The present invention also concerns parasiticidal and pesticidal compositions comprising the isoxazoline compounds of formula (I), processes for their preparation and their uses to prevent or treat parasitic infections or infestations in animals and as pesticides.
Patent EA-036738-B1 (EA)
Title: Method and apparatus for simultaneous sweeping and humming seismic acquisition
Inventor: BRENDERS ANDREW JAMES
IPC: G01V1/38
Filed: 2015-12-02
Abstract: A technique for use in geophysical surveying includes imparting a plurality of humming seismic signals and a plurality of swept seismic signals into a geological formation. The technique also includes receiving returned seismic energy of the plurality of humming seismic signals and the plurality of swept seismic signals after interacting with the geological formation and recording the returned seismic energy.
Patent EA-037674-B1 (EA)
Title: Exchanger element for passenger compartment and passenger compartment equipped with such an element
Inventor: HIRSCH CHRISTIAN
IPC: F28D9/00
Filed: 2016-03-17
Abstract: The invention relates to an exchanger arrangement (3) for the heat transfer and/or selective material transfer between a first fluid (F1) and a second fluid (F2), which can flow through the arrangement (3), said arrangement (3) being constituted of a multitude (n) of adjacent local exchanger elements (E1, E2, ..., En). The exchanger arrangement (3) has at least in some sections a cylindrical shape or the shape of a segment thereof or a prismatic shape having a polygonal base or the shape of a segment thereof. The adjacent local exchanger elements (E1, E2, ..., En) are flat structures that are either wedge-shaped or sheet-like.
Patent EA-035486-B1 (EA)
Title: Method and apparatus for collecting sap
Inventor: KORHONEN ARTO
IPC: A01G23/14
Filed: 2016-09-15
Abstract: The invention relates to a method for collecting sap from a tree, comprising a collection stage and an analysis stage, in which the purity of the sap being collected is determined, wherein, on the basis of the information obtained, the collection stage is terminated. With the aid of the method, sap is produced, in which additives are not used, and which is not heat-treated, and which has, however, good preservability at room temperature. The invention also relates to an apparatus for collecting sap from a tree.
Patent EA-035763-B1 (EA)
Title: Plastic pallet with support blocks having upper and lower towers and associated methods
Inventor: STORTEBOOM JOHN THOMAS
IPC: B65D19/38
Filed: 2017-10-13
Abstract: A pallet includes a top deck and a bottom deck, and spaced apart support blocks coupled between the top and bottom decks and forming a gap therebetween for receiving a lifting member. Each support block includes a mid-section having spaced apart upper and lower surfaces, an upper tower extending from the upper surface of the mid-section, and a lower tower extending from the lower surface. The upper towers are inserted into corresponding upper tower openings in the top deck, and the lower towers are inserted into corresponding lower tower openings in the bottom deck.
Patent ES-2246130-B1 (ES)
Title: Cambiador de herramientas para centros de mecanizado.
Inventor: MUGURUZA ARAQUISTAIN JOSE LUIS
IPC: B23Q3/155
Filed: 2004-03-24
Granted: 2006-12-01
Abstract: Cambiador de herramientas para centros de mecanizado, formado por un conjunto operativo (1) que consta de un accionamiento giratorio (2) dispuesto sobre un soporte de sujeción (3), al cual va acoplada una mesa en cruz (5) que comporta uno o más pares de pinzas (8), con las cuales es susceptible la sujeción de las herramientas para su sustitución respecto de los cabezales portaherramientas de mecanizado.