baber/WOPTO huggingface dataset:
Patent WO-2023071676-A1 (WO)
Title: Anti-her2/anti-pd-l1 bifunctional antibody and application thereof
Inventor: CHEN YILI
IPC: A61P35/00
Filed: 2022-09-28
Abstract: Provided are an anti-HER2/anti-PD-L1 bifunctional antibody and an application thereof. The anti-HER2/anti-PD-L1 bifunctional antibody comprises: a monoclonal antibody unit, wherein the monoclonal antibody unit is directed against HER2 and comprises two heavy chains and two light chains; and a single-chain antibody unit, wherein the single-chain antibody unit is directed against PD-L1 and comprises two single-chain antibodies, each single-chain antibody comprises a heavy chain variable region and a light chain variable region, the heavy chain variable region and the light chain variable region are connected by means of a linker peptide, and the N terminals or C terminals of the two single-chain antibodies are respectively connected to the C terminals of the Fc fragments of the two heavy chains of the monoclonal antibody unit by means of linkers. The anti-HER2/anti-PD-L1 bifunctional antibody can be bound with PD-L1, and can also be bound with HER2, and is a novel antitumor drug.
Patent WO-2023151288-A1 (WO)
Title: 校验数据生成方法、装置、设备及存储介质
Inventor: WU RUIZHEN
IPC: G06F3/06
Filed: 2022-09-29
Abstract: 一种校验数据生成方法、装置、电子设备及计算机非易失性可读存储介质，该方法包括：获取与独立冗余磁盘阵列对应的存储状态矩阵（S101）；在磁盘向量中确定非参照向量，并在非参照向量构成的初始数据区进行数据向量元素均分处理，得到第一数据区和第二数据区（S102）；对存储状态矩阵中的第一数据区和第二数据区进行数据交换处理，得到第一矩阵（S103）；在第一矩阵的第一数据区和第二数据区中确定若干个二阶矩阵组，并对各个二阶矩阵组中的目标磁盘元素进行位置交换处理，得到第二矩阵（S104）；基于第二矩阵进行单纠错编码生成处理，得到第一校验数据（S105）；基于第二矩阵进行双纠错编码生成处理，得到第二校验数据（S106）；该方法可以提高数据恢复速度和效率。
Patent WO-2023088018-A1 (WO)
Inventor: WU MIN
IPC: D21H27/10
Filed: 2022-10-19
Abstract: 本发明公开一种具有防水防油性能的水性涂料及其制备方法和应用。其中，该水性涂料包括如下组分：疏水成分，选自水包油型Pickering乳液；防油成分，选自天然多糖类物质、聚乙烯醇中的一种或几种。其可以解决现阶段无法很好的提供同时具有好的疏水、防水、防油的绿色环保安全的可规模化应用的防水防油涂层的问题。
Patent WO-2023025332-A1 (WO)
Title: Yangtze river basin enterprise screening method and apparatus, electronic device, and storage medium
Inventor: LI HAISHENG
IPC: G06Q10/06
Filed: 2022-10-25
Abstract: The present disclosure relates to a Yangtze river basin enterprise screening method and apparatus, an electronic device, and a storage medium, which are applied to the technical field of environmental protection. The method comprises: obtaining original enterprise data belonging to a preset industry category, comparing the original enterprise data with screened local enterprise data, so as to obtain common enterprise data between the original enterprise data and the local enterprise data; extracting a first text feature from the operation range of the common enterprise data, and extracting a second text feature from the operation range of each enterprise in the original enterprise data; performing feature matching on the second text feature corresponding to each enterprise with the first text feature, and if the matching result meets a preset condition, determining that the enterprise is a first target enterprise. The present disclosure can improve the accuracy of enterprise screening.
Patent WO-2023103723-A1 (WO)
Inventor: WANG ZIYU
IPC: H01L27/00
Filed: 2022-11-16
Abstract: The present invention relates to the technical field of infrared detection, and relates to a thermoelectric array display and a manufacturing method therefor. The thermoelectric array display at least comprises a first pixel point, and the first pixel point comprises a bottom electrode, a P-type thermoelectric leg, an N-type thermoelectric leg, and a top electrode; the P-type thermoelectric leg is disposed on the bottom electrode; and the P-type thermoelectric leg is connected in series to the N-type thermoelectric leg by means of the top electrode. The present invention provides a thermoelectric array display that is strong in information transmission concealment and capable of effectively reducing the heating of a device and achieving long-distance signal transmission.
Patent WO-2023098518-A1 (WO)
Title: 乳双歧杆菌bl-99在保护软骨中的应用
Inventor: HUNG WEI-LIAN
IPC: A61P19/00
Filed: 2022-11-22
Abstract: 乳双歧杆菌BL-99在保护软骨中的应用。本发明提供了一种乳双歧杆菌(Bifidobacterium lactis)在制备用于保护软骨的组合物中的应用，其中，所述乳双歧杆菌为保藏编号CGMCC No.15650的乳双歧杆菌。所述乳双歧杆菌可促进软骨发育、增加软骨密度、保护软骨免受损伤、促进软骨修复和/或改善软骨损伤，有利于软骨健康。
Patent WO-2023185033-A1 (WO)
Title: Heat leakage prevention device and single crystal furnace system
Inventor: LI XIAODONG
IPC: C30B15/02
Filed: 2022-11-28
Abstract: A heat leakage prevention device for a single crystal furnace, and a single crystal furnace system comprising the heat leakage prevention device. The heat leakage prevention device comprises a thermal field structure and a plugging device which are arranged outside the single crystal furnace; a thermal field opening for feeding to the single crystal furnace is provided on the thermal field structure; the plugging device is arranged on the side of the thermal field structure close to the single crystal furnace; the plugging device is movably arranged to expose or completely block the thermal field opening.
Patent WO-2023103825-A1 (WO)
Inventor: QI ZHENGKUN
IPC: H02H7/18
Filed: 2022-11-28
Abstract: 一种电池保护芯片、电池系统及电池保护方法，电池保护芯片（10）包括：放电限压检测电路（11），用于检测上一级电池保护芯片输出的放电驱动信号，并根据本级电池保护芯片的放电检测信号的电流流向识别该放电驱动信号的电平高低，以及减小该放电驱动信号的高低电平转换窗口电压；充电限压检测电路（12），用于检测上一级电池保护芯片输出的充电驱动信号，并根据本级电池保护芯片的充电检测信号的电流流向识别该充电驱动信号的电平高低，以及减小该充电驱动信号的高低电平转换窗口电压。通过该电池保护芯片，解决了现有级联电池保护芯片在进行电池保护时，成本高、不易确定分阻电压比例和功耗大的问题。
Patent WO-2023151352-A1 (WO)
Inventor: WANG LIANG
IPC: G06F9/455
Filed: 2022-11-30
Abstract: Provided in the present application are a memory snapshot management method and apparatus, and a device and a medium. The method comprises: when a memory snapshot generation command is acquired, suspending a virtual machine; copying a two-level page table of the virtual machine to obtain a first snapshot page table, and setting a read-only identifier for a page table entry of the two-level page table; and acquiring a corresponding memory page by means of a page table entry of the first snapshot page table, increasing a reference count of the memory page, and restoring the virtual machine from a suspended state to an operating state.
Patent WO-2023109950-A1 (WO)
Title: Tracking area boundary information processing method and apparatus, electronic device, and readable medium
Inventor: WANG HONG
IPC: H04W4/02
Filed: 2022-12-16
Abstract: The present application provides a tracking area boundary information processing method and apparatus, an electronic device, and a readable medium. The tracking area boundary information processing method comprises: obtaining geographic position information of a terminal relative to a specified base station in a terminal mobility registration updating process; determining pre-stored position information of the specified base station; drawing the geographic position information to an actual map according to the pre-stored position information; and determining a boundary of a tracking area according to a statistical result of the geographic position information on the actual map. According to the embodiments of the present application, the clarity and the visualization degree of the boundary of the tracking area are improved, and the user's perception and experience on various services in the tracking area are improved.
Patent WO-2023142816-A1 (WO)
Title: 障碍物信息确定方法、装置、电子设备以及存储介质
Inventor: WU GANGGANG
IPC: G06V20/58
Filed: 2022-12-23
Abstract: 本申请实施例公开了一种障碍物信息确定方法、装置、电子设备以及存储介质。该方法包括：获取当前车辆预设范围内的至少一个点云数据；其中，所述点云数据包括以所述当前车辆为原点的局部坐标系下的点云坐标；获取至少一个障碍物识别条件，并基于所述障碍物识别条件以及所述点云坐标，识别所述当前车辆预设范围内障碍物的障碍物信息；其中，所述障碍物识别条件包括点云坐标与所述当前车辆之间的检测距离条件、点云坐标与右相邻点坐标之间的第一相邻距离条件、点云坐标分别与左相邻点坐标和右相邻点坐标之间的相邻夹角条件和点云坐标与右相邻点坐标之间的第二相邻距离条件。
Patent WO-2023241009-A1 (WO)
Title: Screen projection method, apparatus and system, device, and storage medium
Inventor: LIU GUANGLEI
IPC: G06F1/3234
Filed: 2022-12-29
Abstract: A screen projection method, apparatus and system, a device, and a storage medium, relating to the technical field of screen projection. The method comprises: in a screen projection state, setting a screen-off duration to a second duration from a first duration, the screen-off duration being a duration when a source device automatically enters a screen-off state, and the second duration being greater than the first duration (201); when a target duration is reached, controlling a screen to be turned off, wherein after the screen is turned off, the source device does not enter the screen-off state, and the target duration is less than the second duration (202); and when the screen is turned off and the second duration is not reached, keeping transmission of a screen projection data stream with a target device (203).
Patent WO-2023241058-A1 (WO)
Title: Image anti-spoofing detection method and apparatus
Inventor: GAO LIANG
IPC: G06V40/40
Filed: 2023-02-01
Abstract: Provided in the embodiments of the present application are an image anti-spoofing detection method and apparatus. The method comprises: performing semantic segmentation processing on an image to be subjected to detection, so as to obtain a first mask image corresponding to a dielectric image block in the image to be subjected to detection; performing biological feature detection on the image to be subjected to detection, so as to obtain boundary information of a biological feature image block in the image to be subjected to detection; performing, on the basis of the boundary information, pixel processing on the image to be subjected to detection, so as to obtain a second mask image corresponding to the biological feature image block; performing an overlapping degree calculation on the dielectric image block and the biological feature image block on the basis of the first mask image and the second mask image, so as to obtain an overlapping degree; and determining, according to the overlapping degree, an anti-spoofing detection result of the image to be subjected to detection.
Patent WO-2023165378-A1 (WO)
Title: Encre, son procédé de préparation et son application
Inventor: KRAGT AUGUSTINUS JOZEF JOHANNES
IPC: C09D11/101
Filed: 2023-02-21
Abstract: L'invention concerne une encre, comprenant les composants suivants en parties en poids : de 10 à 90 parties d'un oligomère à extrémité coiffée, de 0 à 5 parties d'un monomère difonctionnel, de 0 à 30 parties d'un oligomère polymérisable, de 0 à 5 parties d'un tensioactif, de 0 à 5 parties d'un photoinitiateur, et de 0 à 90 parties d'un solvant organique. Par ailleurs, l'invention concerne également un procédé de préparation de l'encre, comprenant les étapes suivantes consistant à : mélanger l'oligomère à extrémité coiffée, le monomère difonctionnel, l'oligomère polymérisable, le tensioactif, le photoinitiateur et le solvant organique pour obtenir l'encre. Un revêtement préparé au moyen de l'encre de la présente invention peut rester stable sous la lumière ultraviolette, et présente les caractéristiques d'une courte longueur d'onde de réflexion, d'un grand déplacement de longueur d'onde et d'une plage de basses températures lorsqu'une longueur d'onde de réflexion réactive est présente.
Patent WO-2023174279-A1 (WO)
Inventor: WANG CHAO
IPC: H01B7/00
Filed: 2023-03-14
Abstract: 本申请公开了一种电能传输总成及车辆，包括至少一根电连接骨架和设置在所述电连接骨架两端的连接器，所述连接器包含连接端子，所述电连接骨架两端与所述连接端子电连接，所述电连接骨架为刚性导体，所述电连接骨架的材质为铜铝复合材质。本申请采用铜铝复合基材，提高了铜铝连接的电学性能和力学性能，降低成本。
Patent WO-2023185471-A1 (WO)
Title: Connector housing having pin fixing structure and connector set
Inventor: WANG RUI
IPC: H01R13/40
Filed: 2023-03-15
Abstract: The present application sets forth a connector housing having a pin fixing structure, and a connector set. The connector housing is provided with a terminal channel used to mount a pin terminal, the terminal channel comprising a terminal positioning cavity formed at a tail end of the connector housing, and the shape of the terminal positioning cavity being consistent with that of a positioning boss of the pin terminal. Thus, when the pin terminal is inserted, the positioning boss of the pin terminal is accommodated in the terminal positioning cavity. An interference rib structure is provided on a side wall of the terminal positioning cavity, so as to achieve a local interference fit between a plug terminal and the connector housing.
Patent WO-2023231592-A1 (WO)
Inventor: DENG LINWANG
IPC: B60L58/10
Filed: 2023-04-13
Abstract: A battery circuit, a control method for a battery circuit, and a vehicle. The battery circuit comprises: a power source end, a first battery pack, a second battery pack of a different type from the first battery pack, a voltage transformation unit, a first switch, a second switch and a grounding end, wherein a positive electrode of the first battery pack is connected to the power source end, and a negative electrode of the first battery pack is connected to a positive electrode of the second battery pack; a negative electrode of the second battery pack is connected to the grounding end; a first end of the first switch is connected to the power source end, and a second end of the first switch is connected to a first end of the second switch; a second end of the second switch is connected to the grounding end; and the voltage transformation unit is connected between the negative electrode of the first battery pack and the second end of the first switch.
Patent WO-2023226657-A1 (WO)
Inventor: HUANG JIANJUN
IPC: H01R13/639
Filed: 2023-04-23
Abstract: 本申请公开了一种防脱落装置及插头组件，防脱落装置用于与插头配合，所述插头包括插头主体以及与所述插头主体连接的插脚，所述防脱落装置能够至少套接于所述插头主体的靠近所述插脚的一端的外周面，所述插头插接于插座时，所述防脱落装置能够抵接于所述插座，防脱落装置能够加强插头与插座的连接稳定性，以减小插头从插座内脱出的概率。
Patent WO-2023217003-A1 (WO)
Inventor: YUAN SHUAI
IPC: G10H1/36
Filed: 2023-05-05
Abstract: 一种音频处理方法、装置、设备及存储介质，该方法包括：响应于第一指示，获取用户上传的一段音频中的人声（201）；响应于第二指示，获取用户上传的另一段音频中的伴奏（202）；响应于第三指示，对人声和伴奏进行混合，以获取目标音频（203）。
Patent WO-2023221936-A1 (WO)
Inventor: ZHANG FAN
IPC: C07K19/00
Filed: 2023-05-15
Abstract: Provided are a protein comprising a PD-L1 binding moiety linked to a TGF β binding moiety, an IL-1 binding moiety, an immunostimulating polypeptide (such as soluble LAG3 or soluble CD4) or a CD47 binding moiety, and a pharmaceutical preparation thereof, a preparation method therefor and the use thereof.
Patent WO-2023236738-A1 (WO)
Inventor: XIONG JIAN
IPC: B60W30/182
Filed: 2023-05-17
Abstract: Procédé et appareil de commande de conduite autonome pour un véhicule et support de stockage informatique, le procédé de commande consistant : à acquérir des informations de perception de véhicule d'un véhicule cible ; à réaliser une reconnaissance de scénario de conduite sur la base des informations de perception de véhicule pour obtenir un résultat de reconnaissance de scénario de conduite ; et dans le cas où le résultat de reconnaissance de scénario de conduite montre que le véhicule cible est dans un scénario de conduite sous-extrême, à commander le véhicule cible pour son entrée dans un mode de conduite autonome sûr, les inconvénients de conduite dans le scénario de conduite sous-extrême étant inférieurs à ceux dans un scénario de conduite extrême mais supérieurs à ceux dans un scénario de conduite normal.
Patent WO-2023237045-A1 (WO)
Inventor: HSU CHUN-HSIANG
IPC: A62C3/07
Filed: 2023-06-08
Abstract: A cooling and fire-extinguishing device (1) for an electric power storage system. The cooling and fire-extinguishing device is arranged at a shell (2), which contains at least one power supply unit (3). A second liquid inlet (10) of the cooling and fire-extinguishing device (1) for an electric power storage system penetrates an outer side of the shell (2); a fluid pipe (20) is arranged on an inner side of the shell (2), one end of the fluid pipe (20) being in communication with the second liquid inlet (10), and the other end of the fluid pipe (20) being in communication with the at least one power supply unit (3); and a sensing unit (40) is electrically connected to a processing unit (30), and senses the temperature of the at least one power supply unit (3) to generate a sensing signal (42). A fluid (F) enters the fluid pipe (20) via the second liquid inlet (10), and the fluid (F) then passes through the fluid pipe (20) to reach the at least one power supply unit (3); and the processing unit (30) receives the sensing signal (42) from the sensing unit (40) and sends an alarm signal (32).
Patent WO-2023241502-A1 (WO)
Inventor: CHEN AI
IPC: H04W48/00
Filed: 2023-06-12
Abstract: 本公开提供了一种接入控制方法、计费方法、装置、通信设备及可读存储介质，属于通信技术领域。本公开实施例的接入控制方法包括：第一网元向第二网元发送第一请求消息，所述第一请求消息包括至少一个非公共网络标识，用于请求更新每个所述非公共网络标识关联的终端数，并从第二网元接收第一响应消息，所述第一响应消息包括第一指示信息，所述第一指示信息用于指示每个所述非公共网络标识关联的终端数是否达到对应的第一值。
Patent WO-2024007952-A1 (WO)
Inventor: ZHOU CHUAN
IPC: H04N19/117
Filed: 2023-06-29
Abstract: 本申请公开了一种环路滤波方法、装置及设备，属于编解码技术领域，本申请实施例提供的环路滤波方法，包括：获取重构样本和重构样本对应的标识，标识用于表征重构样本对应的样本类型；基于与标识相关联的神经网络滤波器对重构样本执行滤波处理，得到目标样本。
Patent WO-2024017115-A1 (WO)
Title: Continuous electrode sheet, bare cell, battery, and electronic device
Inventor: TIAN LEILEI
IPC: H01M4/04
Filed: 2023-07-12
Abstract: The present application provides a continuous electrode sheet, a bare cell, a battery, and an electronic device. The continuous electrode sheet comprises a plurality of first electrode sheets that are sequentially connected. A non-coating part of each first electrode sheet comprises a flat area, a first folding area, and a second folding area. When the first folding area is folded to one side of the flat area and the second folding area is folded to one side of the first folding area, a part of a first conductive layer of the first folding area is exposed relative to the second folding area, a part of a second conductive layer of the flat area is exposed relative to the first folding area, and the first conductive layer of the first folding area and the second conductive layer of the flat area face a same side. When the continuous electrode sheet is electrically connected to a tab, the tab can be electrically connected to both the first conductive layer and the second conductive layer of a current collector. In addition, when the continuous electrode sheet is wound into a bare cell, the first electrode sheets can be wound in sequence, so that automated production is achieved, thereby improving production efficiency.
Patent CO-2017007935-A1 (CO)
Title: Barrera acústica
Inventor: RIVERA VEGA MARÍA DEL PILAR
IPC: E04B1/84
Filed: 2017-08-04
Abstract: La presenten invención corresponde a una barrera acústica que comprende: una primera capa (1), una segunda capa (2) dispuesta sobre la primera capa (1), un primer material aglutinante entre la primera capa (1) y la segunda capa (2), una tercera capa (3) con una matriz de perforaciones sobre la segunda capa (2) y un segundo material aglutinante entre la segunda capa (2) y la 3 tercera capa (3). En donde la primera capa (1) es una espuma, la segunda capa (2) es un textil no tejido y la tercera capa (3) es una lona. Dicha barrera acústica se puede ubicar en establecimientos y recintos cerrados en donde deba de estar en constante movimiento y a su vez, debe tener propiedades que permitan su limpieza y así ubicarla en recintos como hospitales o donde las necesidades de aislamiento de ruido sean importantes.
Patent CO-2018007153-A1 (CO)
Title: Laminado automotriz con acústica mejorada
Inventor: MANNHEIM ASTETE MARIO ARTURO BENJAMIN
IPC: C21D8/00
Filed: 2018-07-09
Abstract: El espesor de acristalamiento automotriz se ha ido reduciendo constantemente a medida que la industria trabaja por mejorar la eficiencia. Un efecto secundario no deseado ha sido un aumento del nivel de ruido dentro de la cabina. Un acristalamiento más delgado y más ligero atenúa menos sonido que el acristalamiento más espeso y más pesado sustituido. Una solución parcial ha sido sustituir un acristalamiento templado monolítico delgado por un acristalamiento laminado de un espesor similar. Esto es una solución eficaz, especialmente cuando se combina con una capa intermedia de atenuación del sonido. Sin embargo, el costo de producir laminados recocidos más ligeros, que también requieren la adición de soportes de montaje debido a la falta de resistencia del vidrio recocido, es mucho mayor que el de piezas templadas. Esta invención proporciona un laminado de costo inferior, con acústica mejorada, que comprende una capa de vidrio exterior templada delgada laminada a una capa de vidrio ultradelgada que se extiende hasta por debajo de la línea de cintura, pero no completamente hasta el borde inferior de la capa de vidrio exterior, permitiendo el uso de elementos de sujeción de orificio pasante convencionales normalmente usados para montar piezas templadas.
Patent CO-2018014368-A1 (CO)
Title: Sistema y método para la administración de sistemas eléctricos, electrónicos y espacios de edificaciones
Inventor: REINOSO CASTILLO JAIME ALBERTO
IPC: G06Q90/00
Filed: 2018-12-28
Abstract: La presente invención se relaciona con un sistema y un método para la administración de múltiples espacios por múltiples usuarios de sistemas eléctricos y electrónicos. El sistema cuenta con la capacidad de administrar recursos eléctricos y electrónicos que incluyen luminarias, equipos de refrigeración y aire acondicionado, equipos de cómputo, video beam, cerraduras y estrategias de acceso y cualquier dispositivo que requiera de un suministro de energía eléctrica. La administración se realiza por medio de un método de gestión de solicitudes de reserva que incluye un módulo administrativo para la gestión, aprobación y agendamiento del espacio, como para la centralización de los controles de usuario, que podrá gestionar de forma autónoma los recursos del espacio (como oficinas, auditorios, entre otros) para el ahorro y uso inteligente de la energía de la edificación; mediante su retroalimentación por medio de sensores de paso, presencia, temperatura, humedad, cámaras, entre otros. También cuenta con un perfil para el usuario final, que incluye su uso en tabletas, celulares inteligentes, computadores, entre otros, desde los cuales podrá gestionar el agendamiento o reserva del espacio y uso de los recursos del espacio en el cual tiene una reserva, permitiéndole gestionar con una antelación prudente la iluminación, temperatura, dispositivos y periféricos del lugar, entre otros.
Patent CO-2021002889-A1 (CO)
Title: Válvula, que permite el llenado y vaciado alternante de un contenedor con un líquido.
Inventor: CORDOBA ZAMBRANO DIEGO LAUREANO
IPC: F16K21/00
Filed: 2021-03-02
Abstract: Válvula que permite el Llenado – Vaciado alternante de un líquido en un tanque o contenedor, donde se utiliza la energía hidráulica disponible para accionar los elementos internos de la válvula, que permiten la entrada y salida del fluido.
Patent CO-2022004259-A1 (CO)
Title: Dispositivo para tratar el estreñimiento
Inventor: GALVEZ URREGO WALTER ANTONIO
IPC: H01L29/84
Filed: 2022-04-02
Abstract: La presente solicitud proporciona un dispositivo para tratar el estreñimiento en las persona sin medicamentos orales, intramusculares o intravenosos y sin métodos invasivos, para mejorar el velocidad y el ritmo intestinal en los órganos asociados a la digestión sin efectos químicos o gástricos colaterales en el tratamiento del estreñimiento por transito lento, este dispositivo identifica la velocidad digestiva por medio de un sensor peristáltico del tracto digestivo y mediante transductores superficiales en la piel sincroniza variables normales de motilidad intestinal y otras partes del tracto digestivo induciendo velocidad peristáltica adecuada mediante transductores.
Patent CO-2022017136-A1 (CO)
Title: Fracción enriquecida del aceite esencial de variedades de lippia alba
Inventor: STASHENKO ELENA
IPC: A61P43/00
Filed: 2022-11-29
Abstract: La invención consiste en una mezcla nutracéutica herbal derivada de aceites esenciales de la planta medicinal Lippia alba, adicionada exógenamente con un terpeno de origen natural, como terapia para el control de la infección crónica por T. cruzi y la prevención de la progresión de la afectación cardiaca asociada a la enfermedad de Chagas