baber/WOPTO huggingface dataset:
Patent AU-608820-B2 (AU)
Title: Mannobiose derivatives
Inventor: MIYAJI HIDEKI
IPC: A61K9/127
Filed: 1988-03-31
Granted: 1991-04-18
Abstract: Novel mannobiose derivative represented by the general formula [I]:   <CHEM> wherein groups of R1 to R5 each represents -OH, -OR6, -NHR6, (R6 represents an acyl group) or a group represented by the following formula (a), (b), (c), (d) or (e), provided that one of R1 to R5 represents -OR6 or -NHR6, one of the other 4 groups of R1 to R5 represents one of the groups represented by the formulae (a) to (e), and the remaining 3 groups of R1 to R5 represent -OH: <CHEM>   <CHEM> wherein @@@@ represents  alpha  or  beta  bond are provided by the invention. These compounds give liposomes a specific affinity for Kupffer cells of liver, and can be produced industrially.
Patent AU-670232-B2 (AU)
Title: Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
Inventor: GOLDIN STANLEY M
IPC: C07D239/42
Filed: 1992-02-10
Granted: 1996-07-11
Abstract: Modulators of neurotransmitter release including substituted guanidines, N''-aminoguanidines, and N,N',N'',N'''-tetra-substituted hydrazinedicarboximidamides, and pharmaceutical compositions thereof are disclosed. Also disclosed are methods involving the use of such neurotransmitter release modulators for the treatment or prevention of pathophysiologic conditions characterized by the release of excessive or inappropriate levels of neurotransmitters. Also disclosed are screening assays for compounds which selectively inhibit glutamate release. Also disclosed are methods of blocking voltage sensitive sodium and calcium channels in mammalian nerve cells.
Patent AU-555784-B2 (AU)
Title: Preparation of (d) 2-(6-methoxy-2-naphthyl) propionic acid
Inventor: MORZE HERWIG VON
IPC: C07C51/487
Filed: 1983-05-26
Granted: 1986-10-09
Abstract: (d)-2-(6-Methoxy-2-naphthyl)propionic acid and pharmaceutically acceptable salts thereof are prepared by resolving mixtures of (d)- and (1)-enantiomers of 2-(6-methoxy-2-naphthyl)propionic precursor acids or salts thereof with N-alkyl- or N-cycloalkyl-D-glucamines or salts thereof to isolate the corresponding (d)-2-(6-methoxy-2-naphthyl)propionic precursor acid which can be readily converted into (d)-2-(6-methoxy-2-naphthyl)propionic acid or a pharmaceutically acceptable salt thereof.
Patent AU-610883-B2 (AU)
Title: Pasteurizable, freeze-driable hemoglobin-based blood substitute
Inventor: HSIA JEN-CHANG
IPC: A61P7/08
Filed: 1988-05-05
Granted: 1991-05-30
Abstract: The present specification describes a process by which a blood substitute (hereinafter referred to as "HemoSafe") is derived from uniformly stabilized monomers and polymers of deoxyhemoglobin in its tight (T) conformation, with oxygen affinity similar to that of human blood. Two classes of HemoSafe are derived respectively from animal-hemoglobin and human-hemoglobin. HemoSafe (animal) differs from HemoSafe (human) in that it is free of polymers in order to reduce potential immunogenicity if used in man. Both types of HemoSafe may be derived in the following manner. The stabilized deoxyhemoglobins are converted to their carbonmonoxy derivatives (CO-HemoSafe) which are then stable under pasteurization conditions to render them viral disease transmission-free. CO-HemoSafes are stable for 2 months at 56 DEG C in either the solution or the freeze-dried state. For transfusion CO-HemoSafes are easily oxygenated under sterile conditions by photoconversion yielding oxy-HemoSafe. In addition a transfusable met-hemoglobin derivative for treatment of cyanide poisoning, is derived by converting oxy-HemoSafe to met-HemoSafe.
Patent AU-755402-B2 (AU)
Title: Method of treating impotence due to spinal cord injury
Inventor: MAYTOM MURRAY CRAIG
IPC: A61K31/00
Filed: 1999-02-23
Granted: 2002-12-12
Abstract: A class of cGMP PDE inhibitors, including sidenafil and pharmaceutically acceptable salts thereof, which can be used to treat sexual dysfunction in male and female animals, especially humans, with a spinal cord injury. The invention can be used to treat sexual dysfunction in male animals that exhibit essentially no residual penile function.
Patent AU-658202-B2 (AU)
Title: Method and device for extending the dynamic range in measurements carried out with a directional coupler
Inventor: KNUUTI MIKA
IPC: G01R27/28
Filed: 1992-06-26
Granted: 1995-04-06
Abstract: PCT No. PCT/FI92/00200 Sec. 371 Date Jun. 9, 1994 Sec. 102(e) Date Jun. 9, 1994 PCT Filed Jun. 26, 1992 PCT Pub. No. WO93/01503 PCT Pub. Date Jan. 21, 1993For extending the dynamic range in measurements carried out with a directional coupler, such as antenna measurements, a signal is supplied to the object under analysis, such as an antenna, through a first port of the measuring directional coupler, part of the signal leaking as a leak signal through a second port of the measuring directional coupler directly towards a measuring device. The signal returning from the object under analysis is measured by the measuring device. To enable the measuring of signal levels lower than before, spurious signals, such as the leak signal, summing to the signal to be measured are eliminated by supplying a phased compensation signal through a second directional coupler to the measuring line.
Patent AU-774698-B2 (AU)
Title: Bone generating product
Inventor: PHILIPPART PIERRE
IPC: A61L26/00
Filed: 2000-12-20
Granted: 2004-07-01
Abstract: The bone generating product comprises a coagulated matrix of platelet rich plasma with a recombinant compound for generating thrombin in presence of at least a phospholipid, and an effective amount of calcium containing compound dispersed in the matrix for inducing the formation of bone.
Patent AU-769672-B2 (AU)
Title: Method and device for continuous analysis of cardiovascular activity of a subject
Inventor: SHUSTERMAN VLADIMIR
IPC: A61B5/02
Filed: 2000-02-11
Granted: 2004-01-29
Abstract: A method for obtaining continuously and non-invasively one or more parameters relating to the cardiovascular system of a subject. The parameters obtainable by the method are systolic blood pressure, diastolic blood pressure, young modulus of an artery, cardiac output, relative changes in vascular resistance, and relative changes in vascular compliance. In accordance with the method, the ratio,  kappa  of the subject's blood flow velocity to the propagation speed of the subject's pulse wave is obtained continuously and non-invasively.  kappa  is then processed so as to obtain the instantaneous values of the desired parameters.
Patent AU-662357-B2 (AU)
Title: Adhesion barrier applicator
Inventor: ADAMS RONALD D
IPC: A61B/
Filed: 1992-10-15
Granted: 1995-08-31
Abstract: An applicator is provided for applying a sheet (80) of surgical material, e.g., an adhesion barrier or other surgical fabric, to internal body tissue. The applicator includes an expandable operating tip (60) which is insertable into an endoscopic tube through an incision in a body to enable a surgeon to apply the adhesion barrier or other surgical fabric to tissue inside the body. A preferred embodiment of the applicator includes a set of telescoping tubes comprising an outer delivery tube (100), a intermediate deployment tube (102), and a inner irrigation tube (104). An expandable spreader tip is mounted at the distal end of the irrigation tube and connected to the distal end of the deployment tube. By advancing the deployment tube and irrigation tube relative to the delivery tube, the spreader tip is exposed at the distal end of the delivery tube. The spreader tip is expanded by movement of the deployment tube relative to the irrigation tube to spread the adhesion barrier over the tissue. A nozzle (116) is provided at the distal end of the irrigation tube for applying a fluid, e.g., a saline solution, to the adhesion barrier. <IMAGE>
Patent AU-675412-B2 (AU)
Title: Method of treating HIV infection
Inventor: THOENE JESS G
IPC: A61K31/165
Filed: 1992-09-30
Granted: 1997-02-06
Abstract: Compounds capable of undergoing a mixed disulfide exchange with a disulfide bond are effective agents for the treatment of HIV infections.
Patent AU-763767-B2 (AU)
Title: Progressive addition lenses with varying power profiles
Inventor: MENEZES EDGAR
IPC: G02B13/00
Filed: 2000-02-15
Granted: 2003-07-31
Abstract: The invention provides lenses, as well as methods for their design and production, in which the power distribution between the distance and near vision zone substantially meets the requirements of the wearer's eye path and refractive power. This power distribution is obtained without introducing additional unwanted astigmatism.
Patent AU-659277-B2 (AU)
Title: Anti-tumour compounds
Inventor: PEGG STEPHEN JOHN
IPC: C07D403/12
Filed: 1993-02-25
Granted: 1995-05-11
Abstract: The invention relates to quinazoline derivatives, or pharmaceutically-acceptable salts thereof, which possess anti-tumour activity; to processes for their manufacture; and to pharmaceutical compositions containing them. The invention provides a quinazoline of the formula:- <CHEM>  wherein R<1> is (1-4C)alkyl; the quinazoline ring may optionally bear one or two further substituents selected from halogeno, (1-4C)alkyl and (1-4C)alkoxy;  R<2> is hydrogen or (1-4C)alkyl;  R<3> includes hydrogen and (1-4C)alkyl; and  Ar is optionally substituted phenylene or heterocyclene; or a pharmaceutically-acceptable salt or ester thereof.
Patent AU-576532-B2 (AU)
Title: Affixing a ribbon to a bag
Inventor: SAITOH TAKASHI
IPC: B65C7/00
Filed: 1984-11-12
Granted: 1988-09-01
Abstract: A bag (12) is continuously fed to a predetermined position. A tie material (15) is continuously fed such that the tie material (15) is close to the bag (12), is able to tie up the open top of the bag (12), and then is severed for a specific length. Also, a ribbon (19) is continuously and longitudinally fed to the open top of the bag (12) and severed for a specific length. A tie piece (15a) severed from the tie material (15) is wound around the open top to tie up the open top together with the ribbon (19) and to affix the ribbon (19) to the bag (12).
Patent AU-731172-B2 (AU)
Title: Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier
Inventor: HUNZIKER ERNST B
IPC: A61K38/00
Filed: 1997-06-24
Granted: 2001-03-22
Abstract: Methods and compositions are provided for the treatment and repair of defects in the cartilage or bone of humans and other animals as in full-thickness defects in joints. To induce cartilage formation, a defect in cartilage is filled with a matrix having pores sufficiently large to allow cartilage repair cells to populate the matrix. The matrix contains an anti-angiogenic agent that serves as a functional barrier to prevent vascularization and bone growth into the cartilage area. The matrix filling the defect in cartilage may also contain a proliferation agent and a chemotactic agent, and a transforming factor in an appropriate delivery system. A functional barrier between the bone and cartilage areas of a full-thickness defect may also be created by heat-treating the areas of bleeding to form a transient tissue barrier which prevents blood vessels and associated cells from penetrating from the bone area into the cartilage area. If desired, the bone portion of the full-thickness defect may be filled with a matrix having pores large enough to allow cells to populate the matrix and to form blood vessels. The matrix filling the bone defect may contain an angiogenic factor and an osteogenic factor in an appropriate delivery system. Methods and compositions are also provided for assisted bone and connective tissue regeneration for dental and other applications.
Patent AU-678762-B2 (AU)
Title: Hand-held dispenser for laying a strip of flexible material under a seal, laying method therefor and uses of said strip
Inventor: BODIN PIERRE
IPC: B05B15/04
Filed: 1993-03-16
Granted: 1997-06-12
Abstract: PCT No. PCT/FR93/00259 Sec. 371 Date Jan. 3, 1995 Sec. 102(e) Date Jan. 3, 1995 PCT Filed Mar. 16, 1993 PCT Pub. No. WO93/18862 PCT Pub. Date Sep. 30, 1993A hand-held dispenser consisting of a dispensing tip to which a strip is fed from a container or a paying-out reel. A strip of flexible material may be laid under one lip of a linear or peripheral seal, and the lip may be held in a raised position when treating or spraying paint onto the area adjacent to and covered by the seal. The dispenser is particularly suitable for use by coachbuilders and vehicle repair shops.
Patent AU-662410-B2 (AU)
Title: Method of producing unsaturated hydrocarbons and separating the same from saturated hydrocarbons
Inventor: RAMACHANDRAN RAMAKRISHNAN
IPC: B01D53/04
Filed: 1993-05-21
Granted: 1995-08-31
Abstract: A gaseous alkene is separated from a gaseous alkane by pressure swing adsorption alone or in combination with distillation wherein the alkene is preferentially adsorbed onto a bed of 4A zeolite at a temperature of at least about 50 DEG C and preferably in the range of 50 to 200 DEG C. Typically, the alkane is propane and the alkene propylene; alternatively, the alkane may be ethane, and the alkene ethylene. <IMAGE>
Patent AU-627483-B2 (AU)
Title: Thermographic imaging
Inventor: LEUNBACH IB
IPC: G01K11/00
Filed: 1989-07-25
Granted: 1992-08-27
Abstract: There is provided a method of and apparatus for thermographic imaging involving the use in electron spin resonance enhanced magnetic resonance imaging (ESREMRI) of a paramagnetic contrast agent having in its esr spectrum a temperature dependent transition. The ESREMRI enhancement of the free induction decay signal resultant on stimulating that transition with radiation of a set frequency or frequency band is itself accordingly temperature dependent.
Patent AU-777650-B2 (AU)
Title: Dispensing/metering device for two-component or one-component adhesive
Inventor: VILLA GIORDANO
IPC: B05B7/02
Filed: 2001-05-07
Granted: 2004-10-28
Abstract: The invention relates to a metering device comprising:   a base plate (1) fitted with heating means (25) and a pipe (7) which connects two openings, at least one (4) of which is located on the upper wall of the said plate two or more tanks (2, 2') designed to rest on the plate, which are fitted with a connector (5) designed to be inserted into the said pipes metering means (8) designed to be connected to the other end of the said pipes (7) to convey the product from the interior of the said tanks through the said plate; the outlet of the said metering means (8) leading to a dispensing head (10) which contains two chambers (28, 29), connected to feed devices that convey the adhesive from each tank, while two nozzles (32, 33) connect the said chambers to two outlets, one of the said chambers (28) also being connected to a second pipe (37) which dispenses the adhesive. <IMAGE>
Patent AU-728689-B2 (AU)
Title: Reusable mandrel for use in a printing press
Inventor: MOSS JAMES R
IPC: B65H27/00
Filed: 1997-11-11
Granted: 2001-01-18
Abstract: A reusable mandrel (300) for use in a plate cylinder of a printing press. The reusable mandrel includes two semi-cylindrical shells (310;312) spaced slightly apart to form a tube having two opposing longitudinal slots (326). Disposed inside the tube is a controller (328) that may be activated in order to selectively adjust the diameter of the tube. The tube is preferably set at an initial diameter so that the tube may incrementally accept plate material from a supply mandrel. Thereafter, the controller may be activated in order to decrease the diameter of the tube so that the tube may be removed from a spool of used plate material. <IMAGE>   <IMAGE>
Patent AU-625686-B2 (AU)
Title: A method of masking tinnitus
Inventor: JUNKER FRANZ
IPC: H04R25/02
Filed: 1989-12-15
Granted: 1992-07-16
Abstract: PCT No. PCT/DE89/00776 Sec. 371 Date Jun. 6, 1991 Sec. 102(e) Date Jun. 6, 1991 PCT Filed Dec. 15, 1989 PCT Pub. No. WO90/07251 PCT Pub. Date Jun. 28, 1990.A tinnitus masker having an electric circuit arranged in a housing and an earpiece which produces a sound spectrum that masks the trinitus is disclosed. The electronic circuit is designed so that the sound spectrum produced by the earpiece contains a line spectrum with a fundamental tone.
Patent AU-690012-B2 (AU)
Title: Electrotransport device having reusable controller power saver
Inventor: GYORY J RICHARD
IPC: A61N1/30
Filed: 1996-01-11
Granted: 1998-04-09
Abstract: An electrotransport system (50) includes a reusable controller (52) having a power source (60) and a separable disposable drug-containing unit (70). The controller (52) contains a switch (62) which disconnects the power source (60) from current drain when the controller (52) is uncoupled from the drug unit (70). A coupling means (74,66,105,72,64,104) physically and electrically connects together the controller (52) and the drug unit (70) such that the controller (52) provides electrical current to the drug unit (70) for electrotransport delivery of the drug to a body surface (eg, the skin) of a patient.
Patent AU-568229-B2 (AU)
Title: Torch nozzle providing an internal mixture
Inventor: BOLOT DENIS
IPC: F23D14/52
Filed: 1985-10-01
Granted: 1987-12-17
Abstract: This nozzle includes an outer case (1) and a core (2) which define in succession: a series of passageways (15) having a zone for the injection of fuel gas and comburent gas, a mixing zone of small section and a primary homogenization zone of larger section; an annular secondary homogenization zone (16) whose section is substantially equal to the total section of the preceding zone; a single acceleration passage (17) having a decreasing section; and a single outlet conduit (18) having a constant section. Application in oxyacetylene torches consuming a few cubic meters per hour acetylene.
Patent AU-771489-B2 (AU)
Title: Fuel cell battery with a stack of planar cells
Inventor: DOGGWILER BRUNO
IPC: H01M8/04007
Filed: 2000-07-26
Granted: 2004-03-25
Abstract: The fuel cell battery has a stack (2) of planar cells (3,4) with alternating electrochemically active plates (3) and interconnectors (4) with intermediate straight or curved zones (20), interconnector profiling to divert two fluids (11, 12) separately through the cells, fluid inlets and outlets and a common outlet channel (5), whereby the second fluid is a heat carrier for reaction heat released during operation. The interconnectors are single-layered and their profiling is designed so that both fluids are guided always in contact with the electrochemically active plate. The direction of flow of the second fluid is reversed at one edge region (24). An Independent claim is also included for an application of a fuel cell battery, e.g. as a current supply component in a car.
Patent AU-732631-B2 (AU)
Title: Acrylate coating methods
Inventor: SHAW DAVID G
IPC: B05D3/06
Filed: 1997-10-31
Granted: 2001-04-26
Abstract: Material such as polypropylene, polyester or nylon, with high oxygen barrier properties is prepared by evaporating polyfunctional acrylate monomer with flash evaporators (43, 47, 49) and condensing the acrylate as a monomer film or by roll coating acrylate monomers onto a plastic sheet (38) in a vacuum chamber (36), using reels (37, 41). Acrylate is polymerized by irradiation by ultraviolet or electron beam (44, 48, 51, 53). A layer of metal or oxide oxygen barrier material is vapor deposited (46) over the first layer of cross-linked acrylate. An acrylate layer is applied over the metal layer. Adhesion of the acrylate layer on the plastic sheet is enhanced by reactive plasma treatment (52) of the surface immediately before deposition, the plasma treatment and coating being conducted in vacuum with less than three seconds between them. Condensation efficiency is enhanced by chilling the surface of the substrate on which the acrylate is condensed to temperatures below 0  DEG C. A backing drum (39, 40) and/or rolls (42) may be cooled to less than -15  DEG C.
Patent AU-674350-B2 (AU)
Title: Locking mechanism for multiple belt grinding machine
Inventor: KAISER RUSSELL E JR
IPC: B24B21/12
Filed: 1993-09-30
Granted: 1996-12-19
Abstract: A locking mechanism for the contouring head assembly of a belt grinding machine that employs multiple, parallel, abrasive grinding belts, and back-up shoes for pressing the belts against the surfaces on a workpiece to be ground. The locking mechanism secures the contouring head assembly to the bed of the grinding machine. The locking mechanism includes a protrusion, such as a ball, that is carried by the contouring head assembly and a pivotable arm with a socket defined near its free end. The pivotable arm is secured to a shaft that is driven by a rotary actuator, that is powered by a hydraulic motor. The socket engages the protrusion to securely support one side of the contouring feed assembly. A hydraulic cylinder forces a tapered plunger against the pivotable arm to enhance the locking action.
Patent AU-571754-B2 (AU)
Title: Sintered aluminous abrasive particles
Inventor: MELOON DAVID RAND
IPC: C09K3/14
Filed: 1985-12-19
Granted: 1988-04-21
Abstract: A method of making sintered aluminous abrasive particles comprises:mixing a quantity of uncalcined bauxite and sulphuric acid to dissolve the acid-soluble portion thereof and form principally aluminium sulphate hydrate;calcining the aluminium sulphate hydrate to separately form gamma alumina and sulphur trioxide;forming the gamma alumina into an unfired body;breaking the unfired body into granules; andsintering the granules to convert the gamma alumina granules into sintered abrasive aluminous material of alpha alumina.
Patent AU-705502-B2 (AU)
Title: Directly cooled, side fired forehearth
Inventor: HULL JAMES D
IPC: C03B7/06
Filed: 1996-05-15
Granted: 1999-05-27
Abstract: A forehearth (20) for cooling glass from a melting furnace as it flows to a feeder bowl (28) from which it is discharged to a forming machine. The forehearth is in the form of an elongate, horizontally extending insulated trough (26) with a roof formed by a longitudinally extending series of roof block elements (30), each of which is of one-piece construction and extends completely across the width of the insulated trough. The downwardly facing surface of each roof block element is contoured to incorporate concave portions (30a, 30b) near the edges of the forehearth, a concave portion (30c) above the center of the forehearth and convex portions (30d, 30e) separating the center concave portion from the side concave portions to substantially impede heat transfer between the side concave portions and the center concave portion. Burners (32) are positioned along the opposed sides of the forehearth to fire transversely into the spaces underlying the side concave portions of the roof blocks, and cooling air passages (40) extend through the roof blocks to discharge cooling air transversely of the forchearth into the space underlying the center concave portion in direct contact with the glass in the forehearth. A plurality of exhaust openings (34, 42) for products of combustion from the burners and cooling air, respectively are positioned along the length of the forehearth to provide for longitudinal flow of products of combustion and cooling air at rates which are variable along the length of the forehearth. <IMAGE>