baber/WOPTO huggingface dataset:
Patent CA-2377573-A1 (CA)
Inventor: ARNDT KATJA M
IPC: C12Q1/00
Filed: 2000-06-26
Abstract: The present invention describes a rapid and efficient <i>in vivo</i> library-<i>versus</i>-library screening strategy for identifying optimally interacting pairs of heterodimerizing polypeptides. It allows for the screening of a protein library against a second protein library, rather than against a single bait protein, and thus has numerous applications in the study of protein-protein interactions. Additionally, it allows for the application of different selection stringencies. Two leucine zipper libraries, semi-randomized at the positions adjacent to the hydrophobic core, were genetically fused to either one of two designed fragments of the enzyme murine dihydrofolate reductase (mDHFR), and cotransformed into <i>E. coli.</i> Interaction between the library polypeptides was required for reconstitution of the enzymatic activity of mDHFR, allowing bacterial growth. Analysis of the resulting colonies revealed important biases in the zipper sequences relative to the original libraries, which are consistent with selection for stable, heterodimerizing pairs. Using more weakly associating mDHFR fragments, we increased the stringency of selection. We enriched the best performing leucine zipper pairs by multiple passaging of the pooled, selected colonies in liquid culture, as the best pairs allowed for better bacterial propagation. This competitive growth allowed small differences among the pairs to be amplified, and different sequence positions were enriched at different rates. We applied these selection processes to a library-<i>versus</i>-library sample of 2.0 x 106 combinations, and selected a novel leucine zipper pair which may be appropriate for use in further <i>in vivo</i> heterodimerization strategies.
Patent CA-2378046-A1 (CA)
Inventor: TZANNES MARCOS C
IPC: H04B3/32
Filed: 2000-07-14
Abstract: A communication system and method for communicating over a wire in a group of wires are described. The communication system includes a first transceiver connected to a first wire in the group of wires and a second transceiver connected to a second wire in the group of wires. Although not directly connected by a wire, the transceivers communicate with each other using electromagnetically coupled signals. For example, the first transceiver transmits signals over the first wire that produced interference on the second wire. The second transceiver detects the interference on the second wire and transmits a communication signal over the second wire that electromagnetically couples to the first wire. The electromagnetically coupled signal conveys a message to the first transceiver that induces the first transceiver to produce a response. The message directs the first transceiver to take an action that adjusts the produced interference. The communication signal has a predefined frequency and phase characteristic that causes the first transceiver to recognize the message.
Patent CA-2378210-A1 (CA)
Title: Microbial process for producing hydrogen
Inventor: MIURA YOSHIHARU
IPC: C12N1/12
Filed: 2000-02-14
Abstract: In the production of hydrogen with the use of microorganisms, the production  of hydrogen by culturing a microalga under light and aerobic conditions and/ or the production of hydrogen with the use of a photosynthetic bacterium under light and anaerobic conditions are performed by using a transparent tower-ty pe air lift culture tank. Hydrogen can be more efficiently produced by using th e above tank having a double cylindrical structure and provided with a helical  flow promoter.
Patent CA-2378254-A1 (CA)
Title: Indicateur de sterilisation lisible par machine et procede de surveillance d'articles a steriliser
Inventor: KIRCKOF STEVE S
IPC: A61L2/26
Filed: 2000-07-05
Abstract: L'invention concerne un indicateur de stérilisation comprenant des indices sensibles à des agents de stérilisation. Cet indicateur permet à un utilisateur de surveiller un cycle de stérilisation sans devoir effectuer de distinction subjective entre la couleur, la qualité ou l'intensité de motifs d'affichage.
Patent CA-2379278-A1 (CA)
Title: Volumetric inductor/eductor
Inventor: GEHRING TODD C
IPC: B05B7/30
Filed: 2002-03-26
Abstract: An inductor or eductor that includes two or more tanks or receptacles that have different volumetric sizes and correspondingly proportional graduate scales by which different incremental volumes of fluids, dry powders, granular materials, etc. can be accurately measured therein. The outlets of the tanks or receptacles are plumbed together so that material in each can be simultaneously evacuated out and into a fluid supply line. Use of the inductor or eductor together with one-way, dry-disconnect valves provides a closed system by which materials such as agricultural chemicals can be accurately, measured, dispensed and transferred.
Patent CA-2381363-A1 (CA)
Inventor: SAFADI REEM
IPC: G06F21/00
Filed: 2000-08-03
Abstract: La présente invention concerne un procédé et un système permettant l'achat-réflexe de services via un réseau de communications tel qu'un réseau de télévision par câble ou satellite. Les services concernés sont essentiellement des informations ou des jeux accompagnant les émissions de télévision, le télé-achat, les services de courrier électronique, et les supports d'information à lecture et enregistrement en continu. La sécurité est assurée par un système d'autorisations produites par le contrôleur d'accès (14) et de jetons d'autorisation produits par un processeur sécurisé. Ce processeur sécurisé est implanté dans le terminal d'abonné (16) par lequel l'abonné se procure les services. Il y a production d'un jeton dès que l'abonné sélectionne le service s'il dispose d'une autorisation préalable ou dès qu'on prend un service par achat-réflexe. Le jeton, qui est sécurisé et signé, peut servir à un serveur de politique ou à un serveur mandataire (18) sous-tendu par le fournisseur de services Internet de l'exploitant de réseau et les services associés de favoriser encore plus l'offre de ces services aux abonnés.
Patent CA-2381693-A1 (CA)
Title: Digital topological analysis of trabecular bone mr images and prediction of osteoporosis fractures
Inventor: WEHRLI FELIX W
IPC: A61B5/055
Filed: 2002-04-12
Abstract: The invention provides method, system and device for determining trabecular bone structure and strength by digital topological analysis, and offers, for the first time, a demonstration of superior associations between vertebral deformity and a number of architectural indices measured in the distal radius, thus permitting reliable and noninvasive detection and determination of the pathogenesis of osteoporosis. A preferred embodiment provides imaging in three dimension of a region of trabecular bone, after which the 3D image is converted into a skeletonized surface representation. Digital topological analysis is applied to the converted image, and each image voxel is identified and classified as a curve, a surface, or a junction; and then associated with microarchitectural indices of trabecular bone to quantitatively characterize the trabecular bone network.  The invention is applicable in vivo, particularly on human subjects, or ex vivo.
Patent CA-2384801-A1 (CA)
Title: Systeme de remise de recompense de type jeu, faisant intervenir l'utilisation d'un reseau ouvert, et procede correspondant
Inventor: PARK KWESOON
IPC: G07F17/32
Filed: 2000-07-26
Abstract: La présente invention concerne un système servant à remettre une récompense au moyen d'un réseau ouvert. Le système comprend un serveur de remise de récompense (13) comprenant une partie d'autorisation (14) servant à autoriser une application de récompense faisant référence à des particularités commerciales de la carte de crédit de chaque client, une partie de gestion (15) servant à fournir des informations d'autorisation relatives à l'application de récompense de chaque client de la part de la partie d'autorisation (14), afin de gérer la remise d'une récompense à chaque client, et une partie fonctionnelle à programme de jeu (16) commandée par la partie de gestion (15), servant à faire fonctionner un programme de jeu, un serveur à bases de données (32) comprenant une base de données client (18) servant à mettre en mémoire une liste de clients ayant une application de récompense autorisée par la partie d'autorisation (14), une base de données de programme de jeu (19) servant à mettre en mémoire différents programmes de jeu, une base de données de points client (30) servant à mettre en mémoire les points de chaque client, et une base de données de points d'entreprise affiliée (31) servant à mettre en mémoire les points de chaque entreprise affiliée, et une scripte (17) servant à lire des données issues des bases de données du serveur de bases de données. Si le client se connecte à une page d'accueil d'une entreprise à cartes de crédit, via le réseau ouvert, et sélectionne l'un quelconque des jeux de type à remise de récompenses ou application à jeux par parties, après un temps désiré de jeu sur le jeu sélectionné, un résultat de remise de récompense du jeu est affiché, ou un gagnant est déterminé par la partie de gestion (15) en fonction des résultats de jeu, et une application d'un perdant est transmise à un gagnant vis-à-vis d'une victoire.
Patent CA-2385052-A1 (CA)
Title: Low dispersion slope waveguide fiber
Inventor: SMITH DAVID K
IPC: G02B6/02
Filed: 2000-08-25
Abstract: Disclosed is a single mode optical waveguide having a core refractive index profile defined by upper and lower boundary profiles on a chart of relative index percent versus radius. The relative refractive index as a function of radial dimensions of the core are selected to provide an optical waveguide fiber having properties suitable for a high performance telecommunication system operating in the wavelength window of about 1530 nm to 1625 nm.  Refractive index profile designs encompassing the wavelength window 1250 nm to 1350 nm are also disclosed. The embodiments of the core waveguide have exceptionally low total dispersion slope and attenuation over these wavelength windows.
Patent CA-2385978-A1 (CA)
Title: Method for securing an array of components for processing in a gas-flush packaging machine
Inventor: LIAKOPOULOS THOMAS
IPC: B65D71/00
Filed: 2002-05-08
Abstract: A method and apparatus described to stabilize and secure individual component items in an array during gas-flushing and packaging, without obstructing or preventing the free flow of the gas-flush throughout the components. In accordance with the present invention, when the array has been composed, it is over-wrapped with a loop of thin, inexpensive, gas-permeable film applied under pressure or shrunk around the array, leaving two opposite faces of the array free of the over-wrapping loop.
Patent CA-2386190-A1 (CA)
Inventor: BEACHY PHILIP A
IPC: A61P25/28
Filed: 2000-10-13
Abstract: The present invention makes available, inter alia, methods and reagents for modulating smoothened-dependent pathway activation. In certain embodiments, the subject methods can be used to counteract the phenotypic effects of unwanted activation of a hedgehog pathway, such as resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function mutations.
Patent CA-2387471-A1 (CA)
Title: Laser safe treatment system
Inventor: SKUTNIK BOLESH J
IPC: A61F9/02
Filed: 2000-10-25
Abstract: A laser treatment system is provided that can be used in any clinical environment without the necessity of additional personal safety equipment. Furthermore, the system provides a large amount of control to the operator/technician and the patient. The system in use combines mechanical and optical methods to protect operators and patients from undesired exposure to laser radiation. According to this approach, safe, portable and fixed embodiments that are useful in a large variety of applications are now possible. Several examples are described.
Patent CA-2390106-A1 (CA)
Title: Improving the crease recovery of fabrics
Inventor: MOONEY WILLIAM
IPC: C11D3/18
Filed: 2000-10-11
Abstract: The crease recovery of fabrics can be improved using C20 - C40 saturated or unsaturated aliphatic hydrocarbons which have melting points below 0~C, such  as squalane. The hydrocarbons may be included in garment care products adapt ed for use in a tumble dryer, such as flexible sheets, in sprayable formulation s or in fabric care compositions, such as fabric conditioning compositions whi ch comprise a fabric softening agent. Fabrics may be treated with the hydrocarbons as part of a domestic laundering process.
Patent CA-2390680-A1 (CA)
Title: Rice peroxidases with various characteristics
Inventor: IWAI TAKAYOSHI
IPC: C12N9/08
Filed: 2000-12-08
Abstract: Peroxidases. The expression specificities of various peroxidases, which can be hardly clarified in the conventional art, are clarified and a means of modifying plants by using the expression specificities thereof is provided. Peroxidases having various expression specificities and promoters originatin g in these peroxidases. Gene expression analysis by using DNA microarrays with  the use of genes of the above peroxidases.
Patent CA-2393028-A1 (CA)
Title: Ear piercing systems with hinged hoop earrings
Inventor: REIL VLADIMIR
IPC: A44C7/00
Filed: 2001-10-16
Abstract: A system for providing safe, effective ear-piercing is provided. The invention provides an earring cartridge carrying a stud having a post in a stud post holder assembly and a nut in slidably aligned, spaced apart, and oppositely opposed placement so that an ear part may be placed between the post and the nut for piercing wherein a torque-like force is produced on the stud post holder assembly causing the assembly to rotatably open when the earring cartridge is compressed to bring the stud towards the nut for engaging the post with the nut. The earring cartridge of the invention is adaptable for use with traditional style ear-piercing studs or with the novel hinged hoop earrings of the present invention. Also provided is a novel nut with a backing shield that prevents the nut from sliding down along the stud post. A  vertically stackable packing box maintains a sterile environment in which an earring cartridge with an ear-piercing earring stud may be transported and stored. An earring-cartridge stud gun provides a cradle into which the earring cartridge may fit. The stud gun can be loaded and unloaded using the packing box in such a way that the operator need not touch the cartridge during either loading or unloading.
Patent CA-2393476-A1 (CA)
Inventor: PELLETIER GEORGES
IPC: C12Q1/68
Filed: 1991-09-20
Abstract: Ogura sterility DNA (I) is carried by a DNA sequence defined by nucleotides 928-2273 of a 2428 base sequence reproduced in the specification. When present in mitochondrial or nuclear genome of a plant it confers cytoplasmic male sterility (CMS). Also included are sequences with at least 50% homology with (I). Also new are (1) recombinant plant nuclear and mitochrondrial genome contg. a DNA sequence defined by nucleotides 928-1569 of the specified sequence (or its homologues); (2) cytoplasm contg. sucha as mitochrondrial genome; (3) Brassica plants or hybrids contg. (I); (4) DNA probes of at least 10 bases form the 928-1569 sequences.
Patent CA-2394352-A1 (CA)
Inventor: CHAN PETER
IPC: H04N7/50
Filed: 2000-12-14
Abstract: An embodiment of the present invention provides a system and method for adaptive video decoding. A method for adaptive video decoding includes determining whether a resource constrained mode is to be initiated, and responsive to a determination that the resource constrained mode is to be initiated, initiating the resource constrained mode, including foregoing the decoding of portions of received video input. For example, adaptive video decoding may include foregoing the decompression and reconstruction of selected video frames during intervals of high demand for memory and/or bus bandwidth resources.
Patent CA-2396433-A1 (CA)
Inventor: PEVERE VIRGINIE
IPC: C07C313/04
Filed: 2001-01-04
Abstract: The invention concerns a method for treating a perfluorinated sulphinic acid on the carbon bearing sulphur, or one of the salts thereof, comprising a step which consists in extracting said acid by contacting it with a liquid basic organic phase.
Patent CA-2396769-A1 (CA)
Title: Method and apparatus for requesting point-to-point protocol (ppp) instances from a packet data services network
Inventor: HSU RAYMOND TAH-SHENG
IPC: H04L12/56
Filed: 2001-01-03
Abstract: A method and apparatus for requesting PPP instances from a packet data services network includes a mobile station configured to send an origination  message to a packet data service node (PDSN) at which it has arrived upon leaving the vicinity of another PDSN. The message informs the new PDSN of th e new location of the mobile station and indicates both the number of dormant PPP instances associated with the mobile station and a service reference identifier for each such PPP instance. A flag within the message may be used  to indicate whether the PPP instances are dormant (i.e., whether the mobile station is engaged in a call).
Patent CA-2400719-A1 (CA)
Inventor: BERGMANN ANDREAS
IPC: H01L41/09
Filed: 2001-02-19
Abstract: A converter for SAW-filters with optimised reflectivity is disclosed, with a  low insertion loss, high selectivity and maximum unidirectionality. The stimulating and/or reflecting base cells of the converter are optimised. Eac h stimulating base cell provides the same level of stimulation and each reflecting base cell provides the integral multiple of a reference reflectio n.
Patent CA-2402410-A1 (CA)
Inventor: RECKER ROBERT R
IPC: C12N15/09
Filed: 2000-06-21
Abstract: The present invention relates to methods and materials used to isolate and detect a high bone mass gene and a corresponding wild-type gene, and mutants thereof. The present invention also relates to the high bone mass gene, the corresponding wild-type gene, and mutants thereof. The genes identified in the present invention are implicated in bone development and in focal adhesion signaling. The invention also provides nucleic acids, including coding sequences, oligonucleotide primers and probes, proteins, cloning vectors, expression vectors, transformed hosts, methods of developing pharmaceutical compositions, methods of identifying molecules involved in bone development, and methods of diagnosing and treating diseases involved in bone development.  In preferred embodiments, the present invention is directed to methods for treating, diagnosing and preventing osteoporosis.
Patent CA-2402413-A1 (CA)
Inventor: UNDERHILL MICHAEL T
IPC: A61K48/00
Filed: 2001-03-13
Abstract: L'invention concerne des compositions servant à promouvoir et à inhiber l'ostéogenèse et des procédés servant à traiter des anomalies osseuses provoquées par une lésion, un effet toxique ou une maladie, ainsi qu'à produire des tissus osseux ex vivo.
Patent CA-2402788-A1 (CA)
Inventor: VASUDEVA KAILASH C
IPC: B25H3/02
Filed: 2000-03-31
Abstract: L'invention concerne une caisse comportant une partie (1) de boîte et un couvercle (2), et des éléments de panneau (10, 12, 12', 35, 38) conçus pour coopérer de manière à s'insérer dans la partie de boîte. Les éléments de panneau sont conçus pour contenir des articles tels que des outils et/ou des éléments d'outil, des articles de loisirs, des trousses spécialisées, des jouets, etc. Les éléments de panneau peuvent être fixés ou non entre eux, et peuvent se situer ou non sur un même niveau. La caisse peut comporter deux ou davantage d'éléments de panneau. Les éléments de panneau peuvent inclure une ouverture destinée à contenir un compartiment (5) de rangement, qui s'étend vers le haut depuis le fond de la caisse et est accessible depuis le fond de la caisse. Dans une forme de réalisation, un élément de panneau inférieur (35) est pourvu d'au moins un élément de panneau plus petit (38), monté coulissant sur celui-ci.
Patent CA-2406340-A1 (CA)
Inventor: BAKER WILLIAM J
IPC: B66F7/20
Filed: 2002-10-02
Abstract: A lift system that coordinates the raising and lowering of a vehicle relative to a surface by using wireless communications is provided. The lift system includes at least two lift mechanisms each having a post, a carriage, an actuating device and a control device. The carriage is slidably coupled to the post and is adapted to support a portion of the vehicle. The actuating device is coupled with the carriage and is capable of moving the carriage relative to the post. The control device is coupled with the actuating device and is capable of communicating by wireless signals with the other control device. The control devices communicate by wireless signals to coordinate the movement of the carriages relative to the posts to raise or lower the vehicle. Further, a rechargeable battery may provide power to the control device to allow for increased mobility of the lift system.
Patent CA-2406661-A1 (CA)
Inventor: GARRITY DAVID FRANCIS
IPC: G03D3/13
Filed: 2001-04-25
Abstract: L'invention concerne un fluide de développement qui s'élève et touche la face inférieure d'une couverture transparente (18). La hauteur normale du fluide est montrée par la ligne (36). Un bord avant (18a) de la couverture est penché vers le haut et comprend une partie découpée (38). Suite à la tension superficielle, le ménisque du produit chimique s'élève et pénètre dans la partie découpée (38). Alors que le bord avant de la partie plaque est au-dessous du bord avant incliné (18a), la surface supérieure de la plaque vient au contact du produit chimique à un endroit où la ligne incurvée formée par la tension superficielle du produit chimique (40) pénètre dans la partie découpée pour recouvrir la plaque selon une ligne droite sur toute la largeur de la machine.
Patent CA-2407118-A1 (CA)
Inventor: MILIVOJEVIC IVAN
IPC: A61M16/16
Filed: 2002-10-09
Abstract: A device for delivering a supply of gases to a usar comprising: a patient interface, in use in fluid communication with said supply of gases, a forehead support adapted to pivot about said interface and in use rest on the forehead of a user and configurable at least in as adjustment mode for selecting a desired fixed relation and a secured mode for securing said desired fixed relation. In one embodiment of the patient interface a mask seals against the face of said user and deliver said gases to the nasal cavity and/or oral cavity and/or throat of said user without substantial pressure on the users face.
Patent CA-2409220-A1 (CA)
Title: Optical fiber cords
Inventor: NAKAO NAOKI
IPC: G02B6/46
Filed: 1999-07-21
Abstract: An optical fiber distribution module achieves high density of connections on one board, yet prevents fiber cord tangling created by repeated connection/disconnection of cords. The module has a connection board with an array of optical connector adaptors for connecting in-use optical fiber cords, and a storage section for storing not-in use optical fiber cords, where a plurality of cord sorting boards having a plurality of fiber cord passageways for accommodating and retaining at least one optical fiber cord is arranged between the connection board and the storage section. This design of the board enables to organize groups of cords into in-use cords and not-in-use cords. The load on the cords are supported properly so that fiber tangling and fiber distortion are prevented. Therefore, high density optical fiber can be achieved without introducing signal distortions.