baber/WOPTO huggingface dataset:
Patent CA-2501651-C (CA)
Title: Use of the quinazoline derivative zd6474 combined with gemcitabine and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability
Inventor: BARGE ALAN
IPC: A61K31/517
Filed: 2003-10-06
Granted: 2011-02-15
Abstract: The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation, particularly a method for the treatment of a cancer, particularly a cancer involving a solid tumour, which comprises the administration of ZD6474 in combination with gemcitabine; to a pharmaceutical composition comprising ZD6474 and gemcitabine; to a combination product comprising ZD6474 and gemcitabine for use in a method of treatment of a human or animal body by therapy; to a kit comprising ZD6474 and gemcitabine; to the use of ZD6474 and gemcitabine in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation.
Patent CA-2510772-C (CA)
Title: Methode et dispositif d'ensemble de capot
Inventor: MUIA-LONGMAN GINA
IPC: B62D25/10
Filed: 2005-06-27
Granted: 2011-11-22
Abstract: La présente divulgation porte sur un ensemble de capot (100) pour véhicule (104). Cet ensemble comprend un capot (102) accouplé au véhicule et pouvant passer de la position ouverte à la position fermée. Ledit ensemble de capot comprend aussi un verrou (106). Le verrou présente une position de blocage pour verrouiller de manière sélective le capot en position ouverte, et une position de libération pour que le capot se déplace de la position ouverte à la position fermée. L'ensemble de capot comprend en outre un dispositif de libération (110) accouplé au verrou pour déclencher le verrou de la position de blocage à la position de libération, tandis que le dispositif de libération peut être actionné par un utilisateur (105) faisant face au capot.
Patent CA-2513292-C (CA)
Title: Arnm circulant utilises comme marqueurs diagnostiques pour des troubles de la grossesse
Inventor: LO YUK-MING DENNIS
IPC: C12Q1/68
Filed: 2004-01-16
Granted: 2016-04-05
Abstract: L'invention concerne des méthodes et des nécessaires pour le diagnostic, le monitorage ou la prévision d'états de pré-éclampsie, d'aneuploïdie chez le foetus, et d'accouchement prématuré chez une femme enceinte, et pour la détection d'une grossesse chez une femme, consistant à mesurer quantitativement dans le sang maternel la concentration d'une ou plusieurs espèces d'ARNm codant pour une sous-unité de la .beta.-gonadotrophine chorionique humaine (hCG-.beta.), le lactogène placentaire humain (hPL), l'hormone de libération de la corticotrophine humaine (hCRH), le suppresseur de métastases Kiss-1 (KISS1), l'inhibiteur de la voie du facteur tissulaire 2 (TPFI2), le gène d'expression spécifique du placenta 1 (PLAC1), ou la glycéraldéhyde-3-phosphate déshydrogénase (GAPDH), et à comparer la concentration des espèces d'ARNm à une valeur de contrôle.
Patent CA-2514779-C (CA)
Inventor: WESTERWICH HELMUT
IPC: G01N33/38
Filed: 2005-08-08
Granted: 2009-05-12
Abstract: The present invention relates to a method for the determination of the CaCO3 content of a scrubbing liquid, which has been separated from a scrubbing liquid circuit of a scrubbing column.
Patent CA-2515849-C (CA)
Title: Confluent exhaust nozzle
Inventor: LAIR JEAN-PIERRE
IPC: F02K3/02
Filed: 2004-02-19
Granted: 2011-05-24
Abstract: A gas turbine engine exhaust nozzle (38) includes a nacelle (16) having an inlet (32) and main outlet (46) at opposite ends, and a main duct (36) extending therebetween. A secondary bypass duct (48) extends radially through the nacelle (16) upstream of the main outlet (46) and includes an unobstructed secondary inlet (50) joined to the main duct (36), and a secondary outlet (52) surrounding the main outlet (46) for collectively discharging exhaust flow in confluent streams.
Patent CA-2516022-C (CA)
Title: Model for studying the role of genes in tumor resistance to chemotherapy
Inventor: FRIDMAN JORDAN S
IPC: A61P35/00
Filed: 2004-02-17
Granted: 2012-05-29
Abstract: The invention provides the components of in vivo and in vitro systems and methods which use them to study the effects of altered expression of a gene activity, such as the human akt, bcl-2, eIF4E or PTEN activities, on the descendants of stem cells that have been engineered to give rise to hematopoietic tumorigenic or tumor cells, such as lymphomas, with a high frequency. The present invention provides vectors, cells and mammals, and methods which in part depend on such products, useful for understanding tumorigenesis and its treatments, and in particular, for identifying and studying inhibitors and activators associated with tumor cell growth and growth inhibition, cell death through apoptotic pathways, and changes in apoptotic pathway components that affect drug sensitivity and resistance in tumorigenic cells. Methods for identifying molecular targets for drug screening, identifying interacting gene activities, for identifying therapeutic treatments and for identifying candidates for new therapeutic treatments are provided.
Patent CA-2516631-C (CA)
Title: Water jet propeller
Inventor: FUSE TOMOHIRO
IPC: B63H11/00
Filed: 2005-08-22
Granted: 2008-01-22
Abstract: To provide a water jet propeller that enables an efficient flow of water from a water flow duct to an impeller housing even with an inner periphery of the impeller housing having an inside diameter smaller than the inside diameter of a rear end portion of the water flow duct. A water jet propeller is constructed as follows. Specifically, a stator is disposed at a rear end portion of an impeller housing. An impeller is disposed inside the impeller housing. The water jet propeller expels a water jet by rotating the impeller. The water jet propeller is further constructed as follows. Specifically, the impeller is disposed so as to circumvent a front end portion of an inner periphery of the impeller housing. The impeller housing includes a liner disposed over a region facing the impeller and representing the inner periphery of the impeller housing less the front end portion. The front end portion is formed to have an inside diameter that gradually increases forwardly.
Patent CA-2518294-C (CA)
Title: Pince de perimetre sismique pour element de plafond suspendu
Inventor: JAHN PETER G
IPC: E04B9/06
Filed: 2005-09-07
Granted: 2009-06-23
Abstract: Une pince de périmètre fait d'un seul morceau de métal en feuille et comprenant des première et seconde jambes pliées à environ 90 degrés les unes par rapport aux autres. La première jambe sert à mettre en prise la jambe verticale d'un angle de mur. La seconde jambe est adaptée pour recevoir la tête ou le bulbe du coulisseau. La première jambe comporte une partie supérieure et une partie inférieure, avec un rebord généralement horizontal reliant la partie supérieure à la partie inférieure. La première jambe comporte une languette ou une patte décalée par rapport au reste de la partie inférieure de sorte que, lorsqu'elle est en place, la jambe verticale de l'angle du mur est maintenue entre la languette et le reste de la partie inférieure. La partie supérieure de la seconde jambe comprend un élément inversé généralement en U dont l'extrémité ouverte forme une auge qui soutient la surface inférieure du bulbe du coulisseau.
Patent CA-2520564-C (CA)
Inventor: MANNING ROBERT FRANCIS
IPC: F01D5/18
Filed: 2005-09-22
Granted: 2014-01-07
Abstract: A turbine airfoil (12) includes an internal cooling circuit (34) between opposite pressure and suction sidewalk (22,24). The pressure sidewall (22) includes a row of outlet slots (36) for the circuit (34) separated by converging partitions (38). Each slot (36) includes an inlet (40), throat (42), and diverging outlet (44). Each of the partitions (38) includes a step (46) in a converging sidewall thereof for increasing divergence of the slots to diffuse coolant discharged therethrough.
Patent CA-2520592-C (CA)
Title: Reverse buckling sanitary rupture disc assembly
Inventor: KREBILL MICHAEL D
IPC: B21D26/049
Filed: 2004-03-02
Granted: 2010-02-16
Abstract: A metal reverse buckling sanitary rupture disc (12) is provided having a central bulged section (16) in which the convex surface of the bulged section (16) is relatively smooth and of substantially uninterrupted configuration. A small segment region (22) of the central bulged section (16) is strain hardened by plastic deformation causing the segment region (22) to have greater residual stress than the remainder of the central bulged section. When the disc (12) is subjected to an overpressure condition against the convex surface of the bulged section (16) sufficient to effect reversal of the bulged section (16), such reversal commences at the higher residual stress segment region (22) of the bulged section (16).
Patent CA-2520705-C (CA)
Title: A thermal spraying apparatus and also a thermal spraying process
Inventor: MUELLER MARKUS
IPC: C23C4/12
Filed: 2005-09-22
Granted: 2012-12-18
Abstract: The invention relates to a thermal spraying apparatus (1) for coating a surface (2) of a substrate (3) by means of a coating material (4). The thermal spraying apparatus (1) includes a spray pistol (5) with a heating device for heating the coating material (4) in a heating zone (6) and also a charging apparatus (7) with a feed (8) through which the coating material (4) can be introduced into the heating zone (6). In this arrangement the thermal spraying apparatus is so designed that a relative position (9) between the feed (8) and the heating zone (6) can be changed in the operating state.
Patent CA-2521525-C (CA)
Inventor: BALDWIN LAURA J
IPC: G06F17/30
Filed: 2005-09-28
Granted: 2013-10-29
Abstract: A system and method are provided for implementing a geographic search mode in connection with a search engine. The method may include indexing geographic locations for resources available to the search engine in a search engine index. The method may additionally include determining a target location for a particular user upon receiving a user query from the particular user and searching the search engine index for geographic location matches matching the target location.
Patent CA-2522724-C (CA)
Title: Cationic polymerization of olefins in the presence of water using dinuclear fluoroaryl co-initiators
Inventor: KENNEDY JOSEPH P
IPC: C08F10/10
Filed: 2004-04-15
Granted: 2012-10-09
Abstract: A method is provided for cationically polymerizing olefin monomer by using a novel coinitiator in the presence of water. More specifically, a method is provided for cationically polymerizing olefin monomer by using a novel coinitiator in an aqueous suspension or aqueous emulsion polymerization process.
Patent CA-2524698-C (CA)
Inventor: PINELLI ENZO
IPC: D04B1/26
Filed: 2004-05-27
Granted: 2010-01-19
Abstract: L'article chaussant thérapeutique présenté comprend des premières rangées de tricot (1) qui alternent avec des secondes rangées de tricot (2) produites avec un nombre de mailles inférieur au nombre de mailles constituant les premières rangées de tricot (1). Les premières rangées de tricot (1) sont constituées d'au moins un fil extensible (1a) et les secondes rangées de tricot (2) sont constituées d'au moins un fil extensible (2a) qui est d'un diamètre plus grand que celui du fil extensible (1a) constituant les premières rangées de tricot (1). L'article chaussant thérapeutique présenté est, sur le plan esthétique, semblable aux articles chaussants élégants et il peut être porté sans problème en n'importe quelle occasion.
Patent CA-2525120-C (CA)
Title: A process for recovering polypeptides that unfold reversibly from a polypeptide repertoire
Inventor: JESPERS LAURENT S
IPC: C07K16/18
Filed: 2004-05-14
Granted: 2013-04-30
Abstract: The invention relates to polypeptides that unfold reversibly (e.g., unfolds when heated and refolds when cooled), to repertoires containing polypeptides that unfold reversibly and to libraries that contain polypeptides that unfold reversibly or nucleic acids that encode polypeptides that unfold reversibly.  The invention further relates to processes for producing a library enriched in polypeptides that unfold reversibly or nucleic acids encoding polypeptides that unfold reversibly, processes for selecting and/or isolating polypeptides that unfold reversibly, and to methods for producing a polypeptide that unfolds reversibly.
Patent CA-2526171-C (CA)
Title: Shear assisted solid state weld and method of forming
Inventor: SHUTE DANIEL MARK
IPC: B23K20/14
Filed: 2004-06-07
Granted: 2011-11-08
Abstract: A shear-assisted solid state welding method for joining of metal parts (1,2), involves a first step of heating opposing surfaces (7,8) of the metal parts (1,2) in a non-passivating environment to a temperature in the hot working temperature range of the metal. A second step involves bringing the opposing surfaces (7,8) into contact while still in the hot working temperature range, and applying compressive stress sufficient to substantially prevent sliding in response to shear displacement, causing plastic flow in the hot layers. A third step involves imposing relative shear displacement of the metal work pieces (1,2) without disengaging the opposing surfaces (7,8). The shear displacement induces plastic shear strain within the hot layers to progressively induce bonding.
Patent CA-2526459-C (CA)
Title: Teaching data preparing method for articulated robot
Inventor: MITSUHASHI YUTAKA
IPC: G05B19/425
Filed: 2004-06-02
Granted: 2008-06-17
Abstract: Set the first temporary attitude of an end effector for a plurality of work points (step S3). Determine the attitude of an articulated robot at one-end first work point out of a plurality of work points (step S4). Determine the attitude of an articulated robot at the-other-end final work point out of a plurality of work points (step S5). Set the second temporary attitudes of an end effector respectively for the other work points so that the attitude of an end effector gradually changes from the first work point toward the final work point (step S6). Correct the first temporary attitude with the second temporary attitude (step S7).
Patent CA-2532261-C (CA)
Inventor: ZECHA FREDERICK P JR
IPC: A61M5/00
Filed: 2004-07-13
Granted: 2013-08-20
Abstract: A needle protective housing is fitted to the neck of a medicament container, for example a glass vial, that has a circumferential notch formed at a proximal portion of the neck. The needle protective device has a needle protective housing pivotally connected to a cup-shaped collar. The collar has a base that is formed by a plurality of coplanar extensions, that in turn form an aperture that allows the base to be press-fitted onto the neck of the vial.  The extensions are each separated by a space, so that the extensions would give way when the collar is slidedly fitted along the length of the neck of the vial, until the extensions reach the notch at the proximal end of the neck of the vial where the extensions return to the original shape to thereby couple the collar to the vial.
Patent CA-2533244-C (CA)
Inventor: NOBLE MAX
IPC: B65G53/24
Filed: 2006-01-18
Granted: 2013-07-16
Abstract: An auger airlock assembly and end dump housing having a spring loaded bottom for use in a bulk loader which utilizes a source of negative pressure to create a suction air stream that draws particulate materials into the loader for transfer, via the auger assembly, to a location remote of the loader. Materials exiting the auger assembly accumulate within the housing to a point wherein, once the accumulated material has acquired a certain weight, the bottom of the housing is forced open to permit discharge of the material, and, once the material is removed, and is not present in enough quantity to maintain the bottom of the housing to remain open, the spring loaded connection biases the bottom back into a position sealably closing the housing. The bottom of the housing may also ne opened by the auger feeding more material into an already full housing, whereby the material is compressed so as to force the door open. Side portions of the housing limit the opportunity for outside air to enter the airlock assembly during the discharge of materials, maintaining the vacuum suction created by the negative pressure in the auger assembly.
Patent CA-2538001-C (CA)
Title: Non-foreshortening intraluminal prosthesis
Inventor: ROUBIN GARY S
IPC: B23K26/38
Filed: 1998-02-04
Granted: 2008-09-30
Abstract: An intraluminal prosthesis (40) is provided with a plurality of annular elements. Each annular element includes a plurality of struts (42, 44) and apices (46) connected to form an annular configuration. Each annular element has a compressed state and an expanded state, and has a longitudinal dimension which is smaller in the expanded state than in the compressed state. A plurality of connecting members (48) connect the apices of adjacent annular elements. The connecting members have a plurality of alternating segments that function to compensate for the smaller longitudinal dimension of each annular element in the expanded state. The stent may be provided with varying flexibility along its length and/or circumference, and may include segments that have different diameters.
Patent CA-2538439-C (CA)
Title: Method and composition for enhanced hydrocarbons recovery
Inventor: SHPAKOFF PAUL GREGORY
IPC: E21B43/22
Filed: 2004-03-10
Granted: 2012-10-02
Abstract: A method of treating a hydrocarbon containing formation is described. The method may include providing a hydrocarbon recovery composition to the hydrocarbon containing formation. Hydrocarbons in the hydrocarbon containing formation may interact with the hydrocarbon recovery composition. The hydrocarbon recovery composition may include an aliphatic anionic surfactant and an aliphatic nonionic additive. In some embodiments, an aliphatic anionic surfactant may be branched. In other embodiments, an aliphatic nonionic additive may be branched.
Patent CA-2541580-C (CA)
Inventor: FUX VADIM
IPC: G06F17/27
Filed: 2006-03-31
Granted: 2011-10-18
Abstract: A method for enabling input into a handheld electronic device having at least three selectable languages available thereon includes detecting a predetermined input a number of times and switching a selected language between one of the three selectable languages and another of the three selectable languages wherein the another language is an immediately preceding selected language.
Patent CA-2543444-C (CA)
Title: Method and apparatus for drying bulk material, especially bark, sawdust, pretreated sludge or a mixture of these, use of a wire, method and apparatus for cooling waste water produced in a production process of pulp or paper, pulp mill and paper mill
Inventor: SAARELA ESKO
IPC: F26B23/00
Filed: 2004-10-29
Granted: 2012-05-22
Abstract: The invention comprises a method and apparatus (1) for drying bulk material, especially bark, sawdust, pretreated sludge or a mixture of these. The invention also comprises a method and apparatus for cooling wastewater produced in a pulp or paper production process. The invention furthermore comprises a pulp mill, paper mill and a novel way of using a wire (21).  According to the invention, in one and the same heat exchanger (13) both wastewater produced in a pulp or paper production process is cooled and, simultaneously, gas that cools the wastewater is heated. Heated gas extracted from the heat exchanger (13) is conducted through one or several drying conveyers (15) and through the material to be dried that is conveyed on the drying conveyer (15), whereby said material is dried with the heated gas.
Patent CA-2544745-C (CA)
Inventor: WACHTEL HERBERT
IPC: A61M16/00
Filed: 2004-11-05
Granted: 2013-08-27
Abstract: An inhaler is described for inhaling powdered medicament from capsules which are placed in a capsule holder (3) provided in the inhaler before use. Once the capsule has been placed in the capsule holder (3) the patient can press an actuating member (8), which can be set in motion from a resting position and thereby interacts with at least one pin (9) adapted to be pushed into the capsule holder (3). By means of the minimum of one pin the capsule is pierced and the medicament is released. The intention is to improve inhalers of this kind in terms of ease of operation. The objective is achieved according to one embodiment of the invention with an inhaler wherein the actuating member (8) is constructed as a multi-functional actuating member (8a) by means of which, in a first functional position, the closure element (6) can be disengaged from the lower part (1) in order to pivot the cover (5), and with which in a second functional position the mouthpiece (4) engaging with the plate (2) can be released from the plate (2) in such a way that the mouthpiece (4) can be pivoted away from the lower part (1).
Patent CA-2548926-C (CA)
Title: Method of data acquisition during survey of buried linear conductors
Inventor: MCDONNELL SHAMUS
IPC: G01V3/00
Filed: 2006-05-10
Granted: 2012-12-04
Abstract: A method of data acquisition during survey of buried linear conductors. A first step involves passing a dynamic data stream of data from survey instruments through a filtering software adapted to reduce the volume of data being processed. A second step involves setting a survey interval within the software, the survey interval being a selected distance between survey points in order to provide a desired survey point density. A third step involves setting a geographic activation buffer within the software in relation to the survey interval. The filtering software is programmed to process data within the activation buffer separately from the dynamic data stream.
Patent CA-2554784-C (CA)
Inventor: DOTSON WILLIAM
IPC: C07K14/195
Filed: 2005-02-04
Granted: 2013-05-28
Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated nucleic acids encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acids as well as methods for producing and using the polypeptides.
Patent CA-2558084-C (CA)
Title: Method of modifying plant seeds comprising modulating expression of mnt transcription factor
Inventor: SCOTT RODERICK
IPC: C07K14/415
Filed: 2005-03-07
Granted: 2019-11-26
Abstract: The invention is a method of modifying cell proliferation in the integuments and/or seed coats of a plant which comprises inhibiting expression or function of a gene encoding Auxin response factor 2 (ARF2/MNT) in the integuments and/or seed coats, whereby cell proliferation, within the integuments and/or seed coats of the plant, is increased.
Patent CA-2561598-C (CA)
Title: Multi-layer films having improved sealing properties
Inventor: PELLINGRA SALVATORE J JR
IPC: B32B27/32
Filed: 2005-04-01
Granted: 2011-06-07
Abstract: Multi-layer films that are suitable for packaging and having improved sealing properties are disclosed. Some embodiments may also provide a lower minimum sealing temperature. A soft polymer is blended in a core layer and a tie layer comprising the soft polymer and, optionally, another polymer. A sealable layer is provided on the side of the tie layer opposite the core layer. The multi~layer films may be transparent, contain a cavitating agent, or are pigmented to form an opaque film. Also, the multi-layer film may be metallized or coated with, a barrier coating.