baber/WOPTO huggingface dataset:
Patent CA-2987547-A1 (CA)
Inventor: BARRITAULT DENIS
IPC: A61P17/02
Filed: 2016-05-26
Abstract: The present invention relates to a pharmaceutical composition including a biocompatible polymer in association with a eukaryotic cell, a platelet extract and/or lysate, or a growth factor, to be used as a drug for the prevention and/or treatment of tissue lesions. The present invention also relates to a pharmaceutical kit which includes a biocompatible polymer in association with a eukaryotic cell for the prevention and/or treatment of tissue lesions. The present invention also relates to the use of a pharmaceutical composition including a biocompatible polymer in association with a eukaryotic cell, a platelet extract and/or lysate, or a growth factor, for manufacturing a drug for the treatment of tissue lesions. The present invention can be used in particular in the veterinary and pharmaceutical fields.
Patent CA-2989966-A1 (CA)
Inventor: DELAHAY KAREN ANN
IPC: C07K14/765
Filed: 2016-08-19
Abstract: The present invention relates to conjugation-competent albumins and albumin-related polypeptides, their conjugates with at least one moiety, and to polynucleotides encoding them. Disclosed is a conjugation-competent polypeptide comprising an amino acid sequence which is at least 90% identical to human albumin of SEQ ID NO. 2, or a fragment thereof being at least 200 amino acids long. The polypeptide comprises 1, 2, 3, 4 or 5 conjugation-competent cysteine residues. At least one of the residues is provided at a position equivalent to a position selected from K93, E230, 1271, E294, E358, L24, F49, V54, D56, H128, F156, E227, D237, K240, K262, Q268, K317, A322, E333, K359, A362, and E382 of SEQ ID NO. 2. The polypeptide has a tendency to exist as a monomer in solution which is at least 70% of the tendency of the human albumin of SEQ ID NO. 2 to exist as a monomer in solution.
Patent CA-2990066-A1 (CA)
Inventor: KRULEVITCH PETER A
IPC: G09B23/28
Filed: 2015-06-22
Abstract: A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical deliver}' device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.
Patent CA-2991182-A1 (CA)
Title: Method of applying a skin beneficial agent to an absorbent article
Inventor: PALMQVIST LISA
IPC: A61K8/11
Filed: 2016-06-22
Abstract: Method of applying a skin beneficial agent to an absorbent article comprising a topsheet layer having a body facing surface and a garment facing surface, the article having a longitudinal front portion, a longitudinal back portion and a crotch portion located between the front and the back portion. The method comprises at least the step of printing,by means of an in-line synchronized print technique, a water based ink composition comprising a binder and a microencapsulated skin beneficial agent on the article,the skin beneficial agent being at least a partly hydrophobic or lipophilic substance or additive, and the microcapsule material being water-insoluble at 20°C.
Patent CA-2991388-A1 (CA)
Inventor: HURREY MICHAEL LAIRD
IPC: A61K31/407
Filed: 2018-01-09
Abstract: This invention provides unit dosage forms of Ketorolac in sterile fluid compositions formulated for continuous subcutaneous delivery via body-worn infusion pump assembly where the Ketorolac is provided at a concentration of between 40 mg/mL and 240 mg/mL formulated for single use delivery in a volume not to exceed 1-10 mL, where the formulation is ethanol-free. In some aspects, the composition is formulated for delivery of a daily dosage of Ketorolac from between about 50 - 120 mg/day, or between 120 mg/mL and 240 mg/mL, and/or in some aspects the composition provides for a maximal volume of infusion which does not exceed 3 mL for single use, and/ or in some aspects the composition comprises Disodium EDTA dihydrate as a preservative and/or in some aspects the formulation is at a pH of about from 7.6 to about 8.0 and/or in some aspects, the maximal volume of infusion does not exceed 1 mL for single use.
Patent CA-2994500-A1 (CA)
Title: Ensemble facade, structure de batiment et procede de montage de l'ensemble facade
Inventor: SCHULZ-HANKE WOLFGANG
IPC: E04B1/94
Filed: 2016-09-14
Abstract: Dans un ensemble façade (14), destiné à un bâtiment (10), qui comprend au moins un élément de façade (16), pouvant être fixé à un bord extérieur de plancher (13) du bâtiment (10), et au moins un élément d'ignifugation (18) incorporé entre l'élément de façade (16) et le bord extérieur de plancher (13), l'élément d'ignifugation (18) comprend une couche d'isolation (19) et une natte d'ignifugation (32). La couche d'isolation (19) comporte une première face latérale (36) dirigée vers l'élément de façade (16) et une seconde face latérale (38), opposée à la première face latérale (36), qui est dirigée vers le bord extérieur de plancher (13) et comporte une face inférieure (40) s'étendant entre les première et seconde faces latérales (36, 38). La natte d'ignifugation (32) enserre la face inférieure (40) de la couche d'isolation (19) et vient s'appuyer sur au moins une partie des première et seconde faces latérales (36, 38). L'invention concerne en outre un procédé de montage d'un tel ensemble façade (14) et une structure de bâtiment utilisant l'ensemble façade (14).
Patent CA-2999331-A1 (CA)
Title: Mass defect-based multiplex dimethyl pyrimidinyl ornithine (dipyro) tags for high-throughput quantitative proteomics and peptidomics
Inventor: LI LINGJUN
IPC: G01N33/68
Filed: 2016-10-14
Abstract: The use of mass defect signatures to impart milliDalton mass differences between isotopically labeled peptides at the MS1-level allows multiplex quantification without the increased mass spectral complexity that occurs with mass difference approaches. Provided herein is a mass defect-based chemical tag, dimethyl pyrimidinyl ornithine (DiPyrO), that is compact and easy to synthesize at high purity in few steps using commercially available starting materials. The multiplex DiPyrO tags are amine-reactive and can impart a mass difference onto labeled peptides and through calculated substitution of heavy isotopes. DiPyrO offers up to 10-plex quantification on current Orbitrap or FT-ICR platforms without increasing mass spectral complexity. The synthesis of the DiPyrO tag is provided along with viability of the DiPyrO tag for labeling complex proteomics samples using yeast extract digests and its effect on labeled peptides during LC-MS2 analysis. Labeling and quantification of glycans and metabolites using the DiPyrO tag is also demonstrated.
Patent CA-3000215-A1 (CA)
Title: Proteines de liaison d'antigene qui activent le recepteur de la leptine
Inventor: GROMADA JESPER
IPC: A61K39/395
Filed: 2016-10-11
Abstract: La présente invention concerne des anticorps et des fragments de liaison d'antigène d'anticorps qui se lient au récepteur de la leptine (LEPR), et des procédés d'utilisation de ces derniers. Selon certains modes de réalisation, l'invention concerne des anticorps et des fragments de liaison d'antigène d'anticorps qui se lient à la LEPR et activent la signalisation par la LEPR. Selon d'autres modes de réalisation, l'invention concerne des anticorps et des fragments de liaison d'antigène d'anticorps qui se lient à la LEPR et améliorent la sensibilisation de la LEPR à un antigène. Selon certains modes de réalisation, l'invention concerne des anticorps et des fragments de liaison d'antigène d'anticorps qui se lient à la LEPR en présence et en l'absence de leptine. Selon certains modes de réalisation, l'invention concerne des anticorps et des fragments de liaison d'antigène d'anticorps qui induisent une signalisation dans des cellules exprimant des mutants de LEPR qui présentent autrement une signalisation défectueuse ou altérée en présence de leptine. Les anticorps et les fragments de liaison d'antigène de la présente invention sont utiles pour le traitement des lipodystrophies et d'autres maladies et troubles associés à ou provoqués par la déficience en leptine ou la résistance à la leptine.
Patent CA-3001221-A1 (CA)
Inventor: KWEON EUNG DU
IPC: F23G5/44
Filed: 2018-04-12
Abstract: The present invention is intended to provide a hybrid combustion apparatus using the pyrolysis of water and combustion air, in which a combustion chamber is defined by a double wall and divided into a primary combustion chamber configured to combust waste and a secondary combustion chamber configured to combust exhaust gas, and the size (diameter) of a combustion unit through which waste is configured to be different from that of the combustion chamber in which a flame is located, so that combustion temperature is further increased by introducing air, so that heated due to proximity to a flame, as combustion air, combustible waste is combusted at an ultrahigh temperature by pyrolyzing water and combustion air by means of a high combustion temperature, and so that complete combustion is achieved by increasing the time for which a flame stays within the combustion chamber, thereby discharging clean exhaust gas.
Patent CA-3002161-A1 (CA)
Title: Nickel-based catalytic composition in the presence of a specific activator and use thereof in a olefin oligomerisation method
Inventor: BREUIL PIERRE-ALAIN
IPC: B01J31/14
Filed: 2016-10-20
Abstract: The invention describes a novel nickel-based composition which comprises: at least one nickel precursor; at least one activator of formula [R3-mAIXm]n; and at least one mixture of a phosphine halide YP(AR<1a>) (A'R<1b>) and a sulphonamide compound of formula R<2>S02NH2 or a preformed ligand, with formula forms 1a), 1b) and/or 1e). Formula (I). The invention also relates to the use of said composition as a catalytic composition in an olefin oligomerisation method, preferably in the dimerisation of ethylene into butene-1.
Patent CA-3003184-A1 (CA)
Title: Tamper evident container
Inventor: GINGRAS RYAN P
IPC: B65D50/14
Filed: 2011-08-09
Abstract: Aspects of the present disclosure relate to a container having tamper evident and resistant features and comprising a tray comprising a bottom wall and a peripheral side wall extending upwardly from the bottom wall and terminating in an outwardly extending flange.  A rib projects upwardly from at least a portion of the flange to at least partially define an open top. A cover comprises a top wall and terminates at a first end of an outwardly extending cover flange. A skirt projects upwardly from an end of the cover flange opposite the first end.  A blocking wall extends upwardly from the top wall and is spaced from the skirt to define a gap between the blocking wall and the skirt. When the cover is mounted to the tray to close the open top of the tray, at least a portion of the skirt lies on top of the rib.
Patent CA-3006363-A1 (CA)
Inventor: GRIFFIN SCOTT J
IPC: B41J2/01
Filed: 2018-05-28
Abstract: A media transport system for conveying sheets of media along a process path extending from a media-uptake zone and thereafter through a print zone. The system includes a transport belt for holding the sheets of media generally flat via vacuum for ink jet printing. The media transport system includes a seamed vacuum transport belt, and a platen supporting the belt. The belt comprises a partially-conductive coating having a surface resistivity of from about 10 1 to about 10 6 ohms per square on a polymeric substrate. The partially-conductive coating comprises a polyester and a conductive component such as carbon black, and optionally includes a plasticizer and a leveling agent. The polymeric substrate is either a thermoplastic or a thermoset material.
Patent CA-3010478-A1 (CA)
Inventor: GURJAR RISHI
IPC: E21B7/04
Filed: 2018-06-29
Abstract: A multiple angle fixed bend assembly comprising a fixed bend housing and an offset bend housing. The fixed bend housing comprises a tubular housing with a first end, a second end and a bore therethrough. A longitudinal axis of the first end of the fixed bend housing is offset relative to a longitudinal axis of the second end of the fixed bend housing. The offset bend housing comprises a tubular housing with a first end, a second end and a bore therethrough. A longitudinal axis of the first end of the offset bend housing is offset relative to a longitudinal axis of the second end of the offset bend housing. The first or second end of the fixed bend housing is configured to connect with the first or second end of the offset bend housing through a releasable connection that allows variation in the axial orientation of a high side of the offset bend housing relative to a high side of the fixed bend housing thereby providing variation of a total bend angle of the assembly. The total bend angle of the assembly is an angle between a longitudinal axis of one end of the multiple angle fixed bend assembly and a longitudinal axis of the opposite end of the multiple angle fixed bend assembly when the fixed bend housing and the offset bend housing are connected by the releasable connection. Also provided is a kit comprising the multiple angle fixed bend assembly and a plurality of annular spacers.
Patent CA-3010708-A1 (CA)
Inventor: TIDMARSH GEORGE
IPC: A61P33/00
Filed: 2017-01-06
Abstract: The present disclosure relates to the use of hepcidin in therapeutic methods for the treatment of various conditions in which decreasing serum iron concentration may be beneficial.
Patent CA-3013055-A1 (CA)
Title: A well tractor drive section with pairs of drive arm bearings mutually oppositely displaced from the centre line
Inventor: ARMSTRONG KENNY
IPC: E21B23/14
Filed: 2017-02-02
Abstract: A well tractor drive section comprising - a drive section body (0) with main central axis (0x), with - first and second drive wheels (10A, 10B) on the outer ends of first and second wheel arms (12A, 12B); - inner ends of said wheel arms (12A, 12B) arranged pivotally about first and second transverse axes (8Ax, 8Bx) in first and second transverse-axial wheel arm bearings (14A, 4B) for said wheel arms (12A, 12B) to rotate in a direction away from said main axis (0x) to engage said drive wheels (10A, 10B) with an inner wall of a well; - said first and second transverse-axes (8Ax, 8Bx) being mutually oppositely laterally displaced with a first separation (d1) from said main central axis (0x) in a common perpendicular plane (8P) relative to said main central axis (0x).
Patent CA-3017543-A1 (CA)
Title: Composition bactericide
Inventor: ZHONG HANGEN
IPC: A01N43/80
Filed: 2016-08-08
Abstract: La présente invention concerne une composition bactéricide. La composition comprend deux principes actifs A et B. Le principe actif A est la benziothiazolinone, le principe actif B est le flutriafol, et les deux ingrédients sont présents selon un rapport pondéral de 1:30 à 30:1 L'invention concerne en outre un procédé de préparation et une utilisation de la composition. Les résultats de test montrent que la composition bactéricide décrite présente un effet synergique évident, et plus important encore, que la quantité d'application est réduite et le coût d'utilisation est réduit. La composition bactéricide permet de prévenir et de traiter efficacement certaines maladies fongiques spécifiques de cultures. Le mélange de bactéricides présentant différents mécanismes d'action et différents modes d'action réduit efficacement la quantité à appliquer de chaque réactif unique, et présente de bons effets sur l'élargissement du spectre bactéricide et le retardement du développement d'une résistance aux médicaments d'un champignon et l'amélioration de l'effet de prévention et de traitement.
Patent CA-3017564-A1 (CA)
Title: Support structure for a wind turbine
Inventor: BARTMINN DANIEL
IPC: E04H12/08
Filed: 2017-03-31
Abstract: The invention relates to a support structure, in particular for a wind turbine, having at least two segments (12, 14, 16), which are joined to one another such that their longitudinal axes (L) extend substantially collinearly to one another. At least one of the segments (12, 14, 16) is a pipe section, which has at least two mutually facing abutment surfaces (18) that are joined to one another, at least in parts. A support structure (10) is provided that is producible in less time and is more cost-effective because the join between the abutment surfaces (18) involves at least one welded join (20), the thickness of the welding join (20) being less than the wall thickness of the pipe section (12, 14, 16), and/or the join between the abutment surfaces (18) involves at least one retaining clip (24).
Patent CA-3019745-A1 (CA)
Title: Compositions et procedes pour liberation selective dans le tractus gastro-intestinal
Inventor: ROZNER DORIT
IPC: C07K14/415
Filed: 2017-03-30
Abstract: La présente invention se rapporte à une composition. La présente composition comprend une ou plusieurs particules de taille micrométrique de type noyau-enveloppe. Le noyau comprend un agent actif et des ingrédients soumis à une dissolution déclenchée par le pH, des ingrédients dégradables par voie enzymatique et/ou des ingrédients insolubles dans l'eau. L'enveloppe comprend un ou plusieurs ingrédients qui sont caractérisés en tant qu'ingrédients entériques, en tant qu'ingrédients dégradables par voie enzymatique, et en tant qu'ingrédients insolubles dans l'eau. Les particules peuvent être dispersées dans un liquide ou une autre composition non sèche.
Patent CA-3019961-A1 (CA)
Inventor: POULI TANIA FOTEINI
IPC: G06T7/90
Filed: 2017-03-27
Abstract: According to the invention, the saturation thresholds (thr; thg; thb) used for this detection depend on color coordinates (rw, gw, bw) representing an illuminant (ILL) of the image.
Patent CA-3020064-A1 (CA)
Title: Dactyloscopie audio basee sur des caracteristiques d'energie audio
Inventor: GREENE PATRICK
IPC: G10L25/54
Filed: 2017-04-07
Abstract: La présente invention concerne la dactyloscopie audio et consiste : à obtenir des échantillons audio d'un morceau audio, à générer des représentations de fréquence d'échantillons audio, à identifier les régions d'énergie croissante et décroissante dans des bandes de fréquence des représentations de fréquence, et à générer des condensés de caractéristiques du morceau audio. Chaque condensé de caractéristiques correspond à des portions des régions d'énergie identifiées apparaissant dans une fenêtre de temps respective. Chaque caractéristique est définie en tant que valeur numérique qui code des informations représentant : une bande fréquence d'une région d'énergie apparaissant dans la fenêtre de temps respective, si la région d'énergie apparaissant dans la fenêtre de temps respective est une région d'énergie croissante ou si la région d'énergie apparaissant dans la fenêtre de temps respective est une région d'énergie décroissante, et un placement de la région d'énergie apparaissant dans la fenêtre de temps respective.
Patent CA-3021375-A1 (CA)
Title: Cup guppy and bottle buddy system and method
Inventor: MARION CLAUDIA T
IPC: A47J45/00
Filed: 2018-10-18
Abstract: A gripper for beverage containers, the gripper including; an elastomeric ring having; an outer surface; and an inner surface; wherein the outer surface and the inner surface are integral with one another separated by a thickness, the inner surface being configured to grippingly-receive and secure a hand-held beverage container such as a bottle or glass or cup for example.
Patent CA-3021617-A1 (CA)
Title: Turret assembly
Inventor: OTTOLINI PATRIZIO GIOVANNI MATIA
IPC: B63B21/50
Filed: 2016-05-24
Abstract: A turret assembly for a vessel comprises a moonpool defined in the vessel and a turret structure rotatably mounted in said moonpool. The turret structure comprises a turret table which by means of a main bearing is rotatably mounted in said moonpool and a hollow turret shaft defined by a surrounding shaft wall, which turret shaft has an upper shaft end connected to the turret table, a substantially cylindrical shaft part that extends downwardly from the turret table and a lower shaft end provided with means intended for cooperation with a lower bearing. The shaft wall of the upper shaft end comprises a widened part surrounding the cylindrical shaft part and defines a circumferential crest, wherein the shaft wall of the upper shaft end, starting from said circumferential crest, extends downwardly towards a position where the upper shaft end is connected to the turret table.
Patent CA-3021702-A1 (CA)
Title: Fault-tolerant power-distribution modules for a power plant
Inventor: Wike Hughes
IPC: G21D3/00
Filed: 2016-04-29
Abstract: Embodiments are directed to fault-tolerant power-distribution modules (PDM). A PDM is included in a power plant to provide a portion of the power generated by the plant as a direct current (DC) signal for the operation of the plant. A power-distribution system distributes a portion of the power generated by the plant to one or more PDMs, as an alternating current (AC) signal. The PDMs provide electrical power to various plant loads. The plant loads may be related to the safety of the operation of the power plant. At least one of the plant loads is a non-safety related load. A PDM may be a DC power supply. The power plant may include one or more power-generating module (PGM) assemblies. At least one of the PGM assemblies may include a nuclear reactor. Accordingly, the power plant may be a modular nuclear power plant.
Patent CA-3022432-A1 (CA)
Title: Sigma receptor binders
Inventor: MARTIN STEPHEN F
IPC: C07D309/14
Filed: 2017-04-29
Abstract: Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, traumatic brain injury, and neuropathic pain.
Patent CA-3023147-A1 (CA)
Inventor: ESTHER CAMERON ALAN
IPC: H01H19/46
Filed: 2018-11-06
Abstract: A switching mechanism includes an actuator rotatable between an off position and an on position; and a timing disc assembly that includes an actuator disc, a bias disc, and a switch disc arranged in a stack. The actuator disc is rotatably connected to the actuator. The bias disc is connected to at least one biasing mechanism. The switch disc is connected to a switch. The actuator disc is configured to engage the bias disc such that the actuator disc is configured to rotate the bias disc to an overcenter position of the at least one biasing mechanism. The overcenter position of the at least one biasing mechanism is configured to rotate the bias disc such that engagement between the bias disc and the switch disc is configured to rotate the switch disc between a closed position and an open position of the switch.
Patent CA-3023180-A1 (CA)
Title: Uplink transmission method based on licensed-assisted access laa system, and apparatus
Inventor: XU KAI
IPC: H04W16/14
Filed: 2016-05-04
Abstract: Disclosed are an uplink transmission method and device based on a licensed-assisted access (LAA) system. The method comprises: for a transmission burst transmitted on an unlicensed carrier, reserving at least one SC-FDMA symbol in a sub-frame of an uplink transmission burst corresponding to the transmission burst, wherein on the at least one reserved SC-FDMA symbol, a user equipment accesses a channel through a listen-before-talk (LBT) access mechanism. The solution can realize a time slot for accessing a channel by means of an LBT being reserved for other UEs in an uplink transmission burst, and the probability of the other UEs successfully accessing a channel is improved, so that a plurality of user equipment in an LAA communication system can perform uplink multiplexing.