baber/WOPTO huggingface dataset:
Patent PT-1587923-E (PT)
Title: Improved constructs for expressing lysosomal polypeptides
Inventor: KOEBERL DWIGHT D
IPC: C12N5/06
Filed: 2004-01-21
Abstract: Provided are isolated nucleic acids for expressing lysosomal polypeptides such as lysosomal acid α-glucosidase (GAA) and vectors comprising the same. In one embodiment, the invention provides an isolated nucleic acid encoding a chimeric polypeptide comprising a secretory signal sequence operably linked to a lysosomal polypeptide. In another representative embodiment, an isolated nucleic acid is provided comprising a coding region encoding a GAA and a GAA 3′ untranslated region (UTR), wherein the GAA 3′ UTR comprises a deletion therein. In another representative embodiment, the invention provides an isolated nucleic acid comprising a coding region encoding a GAA and a 3′ UTR, wherein the 3′ UTR is less than about 200 nucleotides in length and comprises a segment that is heterologous to the GAA coding region. Also provided are methods of making and using delivery vectors encoding lysosomal polypeptides, for example, to produce the lysosomal polypeptide or to treat subjects afflicted with a deficiency in the lysosomal polypeptide.
Patent PT-1669663-E (PT)
Title: Facilitated operation gaseous fuel dispenser pistol
Inventor: FRASCAROLI FRANCO
IPC: F17C5/00
Filed: 2005-10-18
Abstract: A gaseous fuel dispenser pistol (10) comprises a grip (11), a body (14) connected to the grip (11), a fuel dispenser head (16) which can be coupled with a fuel infeed filler (17), coupling elements (19) for holding the head (16) in position on the filler (17) when fuel is dispensed, a shutter (19a) connected to the head (16) to allow or prevent fuel dispensing, a sleeve (13), mobile in a direction "D", relative to the body (14) for operating the coupling means (19), the sleeve (13) being mobile between a first, non-operating position in which fuel dispensing is inhibited and the head (16) is clear of the filler (17), and a second, operating position in which the head (16) is coupled with the filler (17) and fuel dispensing is enabled, there being a lever (18), which can be operated by an operator, cam means (20) located between the lever (18) and the sleeve (13) for increasing variable transmission between the lever (18) and the sleeve (13) in which a predetermined movement of the lever (18) causes a corresponding smaller movement of the sleeve (13), consequently, the resisting force on the lever (18) due to the sleeve (13) reduces in proportion.
Patent PT-1571069-E (PT)
Title: Fastening device for a body part of a motor vehicle
Inventor: GUIHAIRE STEPHANE
IPC: B62D65/08
Filed: 2005-02-28
Abstract: The device has an indexing and guiding unit (9) cooperating with a unit (8) for supporting an air duct seal (2) to allow indexing of a cowl vent grill (1) on the seal along an indexing direction (a) parallel to a windshield of a motor vehicle. The unit (9) allows a hooking unit (6) of the grill to be guided towards the unit (8) along a guiding direction (b) perpendicular to the indexing direction.
Patent PT-1719088-E (PT)
Title: An alarm system
Inventor: STENLUND PETER
IPC: B60R25/102
Filed: 2005-02-07
Abstract: The present invention relates to an alarm system intended to trigger an alarm signal upon deviation from at least one environment-dependent reference predetermined for a specific environment. The alarm system comprises at least one portable unit intended to be placed in said environment, which unit has a size corresponding to a mobile telephone. Each unit comprises a sensor system adapted for detecting different states comprising at least vibrations. Furthermore, the alarm system comprises a processor member connected to the sensor system and adapted for the comparison of signals received from the sensor system and said predetermined environment-dependent reference/references. The alarm system further comprises a communication member connected to the processor member and adapted for wireless communication upon, for instance, the triggering of an alarm signal. Furthermore, the alarm system comprises a memory member connected to the processor member via a distributed computer network and adapted for the storage of said predetermined reference/references.
Patent PT-1755642-E (PT)
Title: Annexin v for preventing plaque rupture
Inventor: FROSTEGAARD ANNA
IPC: A61K38/17
Filed: 2005-04-15
Abstract: Atherosclerosis can be viewed as a response to injury and it is not atherosclerosis per se that is serious but instead factors leading to rupture of atherosclerotic plaques. In the present invention we have identified such factors. A decreased binding of Annexing V to the endothelium was seen in patients with a history of atherothrombosis. The use of native Annexin V or an N-terminal fragment as an active component or a subfraction of immunoglobulins to manufacture a pharmaceutical composition is proposed to improve said binding. The use of Annexin V, N-terminal fragments or immunoglobulins to increase the Annexin V-binding to carotid plaque represents novel mechanism for preventing atherothrombosis.
Patent PT-1662791-E (PT)
Title: Client-server based interactive television program guide system with remote server recording
Inventor: ELLIS MICHAEL D
IPC: H04H60/72
Filed: 1999-07-13
Abstract: An interactive television program guide system is provided. An interactive television program guide provides users with an opportunity to select programs for recording on a remote media server. Programs may also be recorded on a local media server. The program guide provides users with VCR-like control over programs that are played back from the media servers and over real-time cached copies of the programs. The program guide also provides users with an opportunity to designate gift recipients for whom programs may be recorded. <IMAGE>
Patent PT-1881811-E (PT)
Title: Sanitary product
Inventor: HOOI ALEX YU SING
IPC: A61F13/15
Filed: 2006-05-17
Abstract: This invention relates to a sanitary product for use by women for the absorption of menstrual fluid and such like. The product comprises a plug and a pad joined by a sheath. The plug is substantially cylindrical so that is fits comfortably in a vaginal cavity. The pad remains outside the vaginal cavity, but has an absorbent layer on an inward side proximal to the plug and a liquid impermeable layer on an outward side. In use, a wearer can insert a finger into the sheath from the outward side of the pad assist with insertion of the plug into the vaginal cavity. A string is provided that extends inside the sheath from the outward end of the plug to aid removal of the product. A line of weakness extends along the major axis of the pad, about which the pad is disposed to fold in use. This encourages the pad to fold around the plug to accommodate the plug during removal of the product, thus improving hygiene.
Patent PT-2006453-E (PT)
Title: U-shoring frame
Inventor: TRITSCHLER KARL-HEINZ
IPC: E02D17/08
Filed: 2008-06-19
Abstract: The shoring bar (19) has a connection bar (21) fastened to ends of the shoring bar and extending transverse to the shoring bar. The connection bar is arranged at a lower end of a fastening element i.e. flange plate. Two ends of a fastening element are arranged for fastening to a complementary retaining element of carriages (13-16). The shoring bar and the connection bar are formed by metal profiles. The fastening element is provided with throughholes for connection screws.
Patent PT-2093837-E (PT)
Title: Antenna
Inventor: LOSADA JAVIER PAZOS
IPC: H01Q19/30
Filed: 2009-02-18
Abstract: The antenna has a dipole (13) that is made from two pieces. Each piece has a U-shape profile and a V-shape profile with open sections. The two profiles are arranged to each other with their open sections, and are galvanically connected. A connection box and a connecting plug are formed in a single-piece manner.
Patent PT-2143715-E (PT)
Title: Method for obtaining pure enantiomers of a pyridazinone derivative
Inventor: BACKSTROM REIJO
IPC: C07B57/00
Filed: 1997-03-27
Abstract: The invention provides a novel, crystalline polymorphic form of (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]propanedinitrile and a method for making the polymorph. The compound is useful as a cardiotonic agent.
Patent PT-2341273-E (PT)
Title: Tube clamp
Inventor: BAGGENSTOS ROGER
IPC: F16L33/207
Filed: 2010-01-05
Abstract: The clamp (1a) has a clamping ring including a circular section along circumference and a radially outwardly extending ear compressible by a tool. The clamping ring is supported in a clamping ring holder (15a). An ear gap cover plate (23) bridges the circular section in an area of a gap of the ear and is attached to the clamping ring holder. The plate has a reference breaking point (24) such that the plate is detached from the ring holder when the clamping ring is pressed, where the breaking point is designed as a film hinge.
Patent PT-788509-E (PT)
Inventor: KIM SUN HYUK
IPC: A61P5/04
Filed: 1994-08-08
Abstract: Peptide derivatives containing one or more substituents separately linked by an amide, amino or sulfonamide bond to an amino group on either the N-terminal end or side chain of a biologically active peptide moiety. The peptide derivatives have relatively enhanced biological activity when compared to the corresponding peptide alone.
Patent PT-727997-E (PT)
Inventor: WESTERLUND ROLF CHRISTER
IPC: A61K9/107
Filed: 1994-11-03
Abstract: PCT No. PCT/SE94/01032 Sec. 371 Date Dec. 28, 1994 Sec. 102(e) Date Dec. 28, 1994 PCT Filed Nov. 3, 1994 PCT Pub. No. WO95/13066 PCT Pub. Date May 18, 1995A pharmaceutical emulsion for intravenous administration is disclosed which comprises a) a short acting dihydropyridine compound; b) a lipid phase; c) an emulsifier and d) water or a buffer.
Patent PT-789754-E (PT)
Inventor: RAPPUOLI RINO
IPC: C07K14/205
Filed: 1995-11-06
Abstract: The present invention relates to a new method for the growth of Helicobactor pylori and purification of the cytotoxin produced by H. pylori. In particular, H. pylori is cultured in a medium comprising more than 1 gl<-1> of glucose to produce a vacuolating cytotoxin.
Patent PT-788335-E (PT)
Title: Absorbent article
Inventor: CARLUCCI GIOVANNI
IPC: A61F13/15
Filed: 1995-11-21
Abstract: An article is described for absorbing body fluid from a wearer. This comprises a fluid storage region (7) having a first major face on one side thereof and a second major face on the opposite side thereof, and first (6) and second (8) fluid receiving regions adjacent the first and second major faces respectively. Each fluid receiving region (6, 8) receives fluid and releases it to the adjacent major face of the fluid storage region. The fluid receiving regions (6, 8) are each formed of a dry laid web of staple fibers, the web having a bulkiness, as measured under a pressure of 2 kPa, of at least 20 cc/g.
Patent PT-918234-E (PT)
Inventor: REICHERT WERNER
IPC: G02B1/11
Filed: 1997-11-17
Abstract: The composite material comprises a metal band support (1), an interlayer (2) and a multilayer optical system (3) having a nonmetallic protective layer (4) of low-absorption material with a thickness (D4) of 5-20 nm, preferably 5-10 nm, applied to the optical system.
Patent PT-898699-E (PT)
Inventor: RICCI ANTONIO
IPC: G01N1/36
Filed: 1997-05-13
Abstract: On a base structure (101, 103), an assembly (104) oscillates about a horizontal axis (X-X) between two limit positions; on said assembly, a rotor (106) is capable of rotating about an axis (Y-Y) of rotation orthogonal to said horizontal axis (X-X) and has a ring of seats (121) for test tubes (1); an actuator (145) moves said assembly into a position with the axis of rotation (Y-Y) roughly horizontal, to carry out an agitation stage, and into a position with the axis of rotation (Y-Y) vertical, to carry out, before the reading stage, a centrifugation stage. The ring of seats (121) for test tubes (1) oriented, in the vertical position of said axis of rotation (Y-Y), with their bottom facing downwards and outwards.
Patent PT-914299-E (PT)
Inventor: KHIATI NATHALIE EL
IPC: C03C3/087
Filed: 1998-03-12
Abstract: The subject of the invention is a glass composition of the silica-soda-lime type, intended for the manufacture of substrates or sheets, the said glass composition having a phi coefficient of between 0.50 and 0.85 N/(mm2.° C.) and a working point of less than 1200° C.
Patent PT-998296-E (PT)
Inventor: ZOGRAFOS NIKOLAOS
IPC: A61P3/06
Filed: 1998-07-24
Abstract: The alcoholic extract of the fruits of Cypraesus Semprevirens was prepared, in order to be used for the prevention and treatment of metabolic disturbances of cholesterol, triglycerides and generally lipids, in humans and animals. Other types of extracts as well as the active constituents, isolated by elaborating various parts of the cypress tree and other relative coniferous trees, are effective in the prevention and treatment of every type of hypercholesterolemia and lipids' disturbances. The administration of combination of the above fractions and substances (of natural or synthetic origin) resulted in the significant reduction of cholesterol and LDL levels as well as in prevention of atheromatic lesions. Substances belonging to the above mentioned groups, mixtures of them as well as salts and esters, of natural or synthetic origin, administered in various ways may act preventively and therapeutically in various types of hypercholesterolemia and atheromatosis, in humans and animals.
Patent PT-999259-E (PT)
Inventor: KENDRICK ANDREW
IPC: A23C9/123
Filed: 1999-11-02
Abstract: Marine oil is stabilized by treatment with silica in the presence or absence of carbon, vacuum steam deodorisation at a temperature between about 140 DEG  C and about 210 DEG  C in the presence of 0.1-0.4% deodorised rosemary or sage extract. If desired 0.01-0.03% ascorbyl palmitate and 0.05-0.2% mixed tocopherol can be added.
Patent PT-1108207-E (PT)
Title: Optical-based sensing devices
Inventor: COLVIN ARTHUR E JR
IPC: G01N21/27
Filed: 1999-08-26
Abstract: An optical-based sensor (10) for detecting the presence or amount of an analyte using both indicator and reference channels. The sensor has a sensor body (12) with a source of radiation embedded therein (18). A matrix layer is disposed on the surface of the sensor body which layer is permeable to an analyte and comprises fluroescent indicator molecules responsive to the concentration of the analyte. Radiation emitted by the source interacts with indicator membrane (3) indicator molecules (16) proximate the surface of the body. At least one optical characteristic of these indicator molecules varies with analyte concentration. For example, the level of fluorescence of fluorescent indicator molecules or the amount of light absorbed by light-absorbing indicator molecules can vary as a function of analyte concentration. In addition, radiation emitted by the source also interacts with reference membrane indicator molecules proximate the surface of the body. Radiation (e,g., light) emitted or reflected by these indicator molecules enters and is internally reflected in the sensor body. Photosensitive elements within the sensor body generate both indicator channel and reference channel signals to provide an accurate indication of the concentration of the analyte.
Patent PT-1140932-E (PT)
Inventor: PICAUT GUY
IPC: A61K31/4745
Filed: 1999-12-20
Abstract: Novel 1,8-benzo-naphthyridine derivatives of general formula (I):which are useful as antimicrobial agents.
Patent IE-880202-L (IE)
Title: Making n,n-(dibenzohexatrienylene)-ureas.
IPC: C07D223/22
Filed: 1988-01-26
Abstract: N,N-(dibenzohexatrienylene)urea medicaments can be manufactured in a smooth one-step reaction by reacting a corresponding N,N-(dibenzohexatrienylene)amine with cyanic acid.
[US4847374A]
Patent IE-42482-L (IE)
Title: Immobilised enzyme conjugates
IPC: B01J31/06
Filed: 1976-02-18
Abstract: The enzyme fixed to a support is composed of a combined organic-inorganic base material, which consists of an inorganic porous support having an organic polymer, which contains functional groups, partially adsorbed and enclosed in its pores, and of an enzyme which is partially adsorbed to the base material and bound covalently to the functional groups of the organic polymer in the terminal regions of this polymer. Such immobilised enzymes are of use in the biochemical and fermentation industries. They are obtained, in particular, by drenching a porous support with a solution of a polyfunctional organic compound and treating the impregnated support with an excess of a bifunctional monomer. Subsequently, the enzyme is added, part of which enzyme then binds covalently to reactive groups of the polymer which has been formed and which is present in and on the support. During this procedure, the biochemically active residues of the enzyme must not be blocked or altered.
[GB1537086A]
Patent IE-800930-L (IE)
Title: Cutting out and transporting a block of silage
IPC: A01F25/20
Filed: 1980-05-06
Abstract: A device for cutting out and transporting a silage block, comprising a main frame which may be connected to a tractor and which comprises an at least approximately horizontal cross-beam, which carries a plurality of parallel tines and to which an upstanding main frame part is connected, which supports near its upper end an at least approximately horizontal frame member, along which a drive housing may be reciprocated. A sawing or cutting means is guided in this drive housing for upward and downward movement. The upstanding main frame part further supports a pressure frame underneath said frame member which extends near the track of the sawing or cutting means and which may be displaced by actuating means. The pressure frame comprises a plurality of pressure frame parts which are displaceable with respect to each other.
[US4341354A]
Patent FI-830092-L (FI)
Inventor: MOTOV DAVID LAZAREVICH
IPC: C14C3/04
Filed: 1983-01-11
Abstract: PCT No. PCT/SU81/00043 Sec. 371 Date Jan. 18, 1983 Sec. 102(e) Date Jan. 18, 1983 PCT Filed May 19, 1981 PCT Pub. No. WO82/04071 PCT Pub. Date Nov. 25, 1982.A leather tanning agent characterized in that it contains the following components, percent by weight: -sulphate of aluminum and ammonium  3 to 20 -containing 0.001 to 1.0% of TiO2 or -TiO2 and ZrO2 -and/or sulphate of zirconium and ammonium 20 to 50 -containing 0.001 to 0.5% of TiO2 -or TiO2 and Al2O3 -and sulphate of titanyl and ammonium -containing of 0.001 to 1.0% of Al2O3 -and/or ZrO2 the balance. -  The above-mentioned additives of TiO2, ZrO2 and Al2O3 incorporated in the sulphates are present therein in a chemically combined state. In the process for producing the leather tanning agent a titanium-containing solution with a concentration of titanium of from 80 to 200 g/l as calculated for titanium dioxide is reacted with a solution of aluminum sulphate containing 80 to 130 g/l of aluminum as calculated for alumina, and/or a solution of zirconium sulphate containing 50 to 200 g/l of zirconium as calculated for zirconium dioxide in the presence of sulphuric acid and ammonium sulphate. The sulphate tanning agent according to the present invention can be very useful in the leather industry.
Patent FI-852963-L (FI)
Inventor: TOWNSEND PALMER W
IPC: C07C31/36
Filed: 1985-07-31
Abstract: A continuous process is disclosed for preparing 2,2,2-trifluoroethanol from 2-halo-1,1,1-trifluoroethane, preferably 2-chloro-1,1,1-trifluoroethane. In the process, 2-halo-1,1,1-trifluoroethane, a carboxylic acid salt and a hydroxylated compound such as water are continuously provided to a reaction mixture in a reactor. The 2-halo-1,1,1-trifluoroethane, the carboxylic acid salt and the hydroxylated compound are reacted therein at a reaction pressure at or above the autogenously developed pressure and at a reaction temperature of from about 223°C to about the critical temperature of the hydroxylated compound. At least a portion of the reaction product mixture is continuously withdrawn from the reactor and unreacted 2-halo-1,1,1-trifluoroethane is separated therefrom. The separated unreacted 2-halo-1,1,1-trifluoroethanne is recycled as part of the 2-halo-1,1,1-trifluoroethane provided to the reaction mixture. The 2,2,2-trifluoroethanol is recovered from the reaction product mixture.
Patent IE-781310-L (IE)
Title: Facsimile transmission installation
IPC: H03M7/46
Filed: 1978-06-29
Abstract: The invention relates to a reduced redundancy facsimile transmission installation which includes at the transmission end means which form run length words from the binary data analysis of a document. In accordance with the invention, at the transmission end, an array of combinatorial logic circuits (26), preferably of the PLA type, is programmed to transcode run length words into other words, using a truncated Huffman code and, at the receiving end, arrays which are also preferably of the PLA type provide inverse transcoding. Application: facsimile transmission.
[US4228467A]
Patent IE-871830-L (IE)
Title: Sustained release pharmaceutical compositions.
IPC: A61K9/26
Filed: 1987-07-08
Abstract: Oral dosage forms for neutral, zwitterions or salts of acidic or basic drugs with approximate zero order release kinetics comprise a core matrix of the drug, and a gelling polymer, the matrix being coated with a water permeable but insoluble polymer.
Patent IE-40168-L (IE)
Title: Diamond synthesis
IPC: C01B31/06
Filed: 1974-09-09
Abstract: The invention provides elongate synthetic RD diamond particles, each particle having a long axis and a short transverse axis, the ratio of the long axis to the short axis being at least 3 to 1. Each particle generally has a rib bed structure down its long axis, the ribs of the structure being traces of {111} crystallographic planes and the long axis providing a backbone for the structure and being in the direction <100> crystallographic direction. The invention further provides a resin bond grinding wheel in which these particles are radially oriented. The particles may be made by providing a body of solvent metal in contact with a body of carbonaceous material in a reaction zone, producing zones of the weakness in the carbonaceous body and subjecting the contents of the zone to conditions of pressure and temperature suitable for RD diamond growth so causing the solvent metal to penetrate the zones of weakness and produce the particles.
[US4036937A]
Patent IE-902388-L (IE)
Title: Vasoactive intestinal peptide analogs.
IPC: C07K1/04
Filed: 1990-06-29
Abstract: Novel vasoactive intestinal peptide analogs containing substitutions of appropriately selected amino acids at specific positions of the VIP molecule.
[EP0405242A2]
Patent IE-842460-L (IE)
Title: Luquid level control valve
IPC: E03D1/32
Filed: 1984-09-27
Abstract: A fill valve for controlling liquid level in a toilet water tank or other tank includes a valve head assembly positioned at a selected level in the tank by a telescoping riser assembly with liquid inlet and outlet conduits extending toward the tank bottom. An adjusting nut on a stationary riser engages thread structures on inlet and outlet conduits for raising or lowering the valve head assembly and adjusting the liquid level. A main valve in the head assembly is controlled by a non-horizontal diaphragm separating a vent chamber and a control chamber. The control chamber is pressurized as liquid rises to the selected level by a standpipe extending downwardly in the tank. The valve closing and opening levels are offset by partly filling the vent chamber with liquid when the main valve is open to hydraulically load the diaphragm. A vacuum breaker valve obstructs backflow through the valve, vents the flow path when the valve is closed, and regulates flow into the vent chamber when the valve is open.
[US4574826A]
Patent IE-892667-L (IE)
Title: Adhesive component for the treatment of collagen-containing¹materials
IPC: C09J133/14
Filed: 1989-08-18
Abstract: Preparations containing (meth)acrylates containing formamide groups and, if desired, an initiator can be used as an adhesive component for treating collagenous materials.