baber/WOPTO huggingface dataset:
Patent NZ-510621-A (NZ)
Title: Customizable seat cushion and positioning assembly including pressure compensation inserts
Inventor: CHEW NORMAN
IPC: A61G5/10
Filed: 1999-11-03
Abstract: A seating system and, more particularly, seat cushion assemblies having a rearward depression and cushioning insert tailored to fit under the skeletal structure of the user. The assembly preferably includes an intermediate insert which fits within a base depression and a cushioning insert which can be a fluid bag, air bag, foam or gel. The insert is generally oval shaped and has a rounded bottom. This enables the cushion to be used to fit under the seating bones so as to provide a proper pelvic tilt. Further, the insert can be moved in order to provide controlled movement of the pelvis over time. A first cushioning insert is generally constructed of a material forming baffles so as to define air chambers and having a right and left seat bone area. A second design has a top and bottom so as to define the fluid envelope separated by central baffle having apertures to allow fluid communication between the right and left portions. Also described are tapered wedges which can be removed to lower one side of the leg well and the base cushion to allow for self-proportion on the part of the user. Rigid stabilizers support the edges of the base cushion.
Patent NZ-511117-A (NZ)
Title: Use of prucalopride for the manufacture of a medicament for the treatment of dyspepsia
Inventor: SCHUURKES JOANNES ADRIANUS JAC
IPC: C07D405/12
Filed: 1999-11-16
Abstract: Described is the use of prucalopride or a pharmaceutically acceptable addition salt thereof for the manufacture of a medicament for the treatment of patients having dyspeptic symptoms due to a decreased motility of the colon. The dyspeptic symptoms comprise lack of appetite, the feeling of fullness, early satiety, nausea and vomiting, and bloating or gaseous eructation.
Patent NZ-514669-A (NZ)
Title: Composition and method for road-film removal
Inventor: HOYT JERRY D
IPC: C11D1/14
Filed: 2000-03-09
Abstract: An aqueous solution at a pH between 1.0 and 13 comprising: (a) at least one anionic surfactant selected from linear alkyl benzyl sulfonates, alpha olefin sulfonates, alkyl sulfates and secondary alkane sulfonates, (b) at least one poly(oxyalkylene) ammonium cationic surfactant of formula (I), wherein R, R1, and R2 are independently C1-4alkyl groups, R3 comprises a polyoxyalkylene chain, and X is an anion. The solution is used as a cleaning composition.
Patent NZ-520698-A (NZ)
Title: A method of screening for a binding site that interacts with a binding molecule comprising screening a molecular library
Inventor: PUIJK WOUTER CORNELIS
IPC: G01N33/50
Filed: 2001-02-16
Abstract: Described particularly are protein-protein, protein- nucleic acid, nucleic acid-nucleic acid and biomolecule- ligand interactions in the field of molecular recognition or detection of discontinuous or conformational binding sites or epitopes corresponding to a binding molecule. A synthetic molecular library is provided that allows testing for, identification, characterisation or detection of a discontinuous binding site capable of interacting with a binding molecule, the library having been provided with a plurality of molecules, each molecule comprising at least one first segment linked to a second segment, each segment having the capacity of being a potential single part of a discontinuous binding site.
Patent NZ-524274-A (NZ)
Title: Antisense insulin-like growth factor binding protein (IGFBP)-2-oligodeoxynucleotides for prostate and other endocrine tumor therapy
Inventor: GLEAVE MARTIN
IPC: A61K31/7088
Filed: 2001-09-13
Abstract: Compositions and a method are provided for the treatment of prostate and other endocrine tumours in mammals, including humans, by administration of an antisense oligodeoxynucleotide (ODN) complementary to a portion of the gene encoding IGFBP-2. Using the human prostate cancer LNCaP tumour model in vitro and in vivo, the administration of such an ODN was shown to reduce proliferation of tumour cells, and also to delay the progression to androgen independence.
Patent NZ-527251-A (NZ)
Title: Heterocyclic inhibitors of ERK2 and uses thereof
Inventor: CAO JINGRONG
IPC: C07D413/14
Filed: 2002-02-08
Abstract: Disclosed is the use of a compound of formula I for the manufacture of a medicament for inhibiting ERK-2 activity, wherein: Sp is a 5-membered heteroaromatic ring, wherein Ring A and QR2 are attached to Sp at non-adjacent positions, and wherein Sp has up to two R6 substituents, provided that two substitutable carbon ring atoms in Sp are not simultaneously substituted by R6, Z1 and Z2 are each independently selected from N or CH, each of T and W is independently, an optionally substituted saturated or unsaturated alkylidene chain, wherein up to 2 saturated carbons of the chain are replaced by -CO-, -C(O)C(O)-, -C(O)NR7-, -C(O)NR7NR7-, -CO2-, -OC(O)-, -NR7CO2-, -O-, -NR7C(O)NR7-, -OC(O)NR7-, -N(R7)N(R7)-, -NR7C(O)-, -S-, -S(O)-, -S(O)2-, -NR7-, -SO2NR7-, or -NR7SO2-, and the remaining substituents are defined herein.
Patent NZ-527779-A (NZ)
Title: Process for the preparation of (3-cyano-1H-indol-7-yl)(4-(4-fluorophenethyl)piperazin-1-yl)-methanone and salts thereof
Inventor: CRASSIER HELENE
IPC: C07D211/72
Filed: 2001-12-21
Abstract: Process for the preparation of (3-cyano-1H-indol-7-yl)[4-(4-fluorophenethyl)piperazin-1-yl]methanone of formula I where: 1) an indole ester of formula II is formylated, where R is an alkyl group having from 1 to 6 carbon atoms or arylalkyl. 2) The formyl ester of formula III is formed from (1) is reacted with hydroxylamine to give an oxime derivative of formula IV, where R is defined above. 3) The oxime of formula IV is converted into a cyanoindole ester of formula V, where R is defined above. 4) The ester of formula V is saponified to give 3-cyano-1H-indole-7-carboxylic acid, and 5) The 3-cyano-1H-indole-7-carboxylic acid is reacted with 1-[2-(4-fluorophenyl)ethyl]piperazine to give the compound of formula I, and 6) The resultant base of formula I is converted into one of its salts by treating with acid.
Patent NZ-528500-A (NZ)
Title: Methods for the synthesis of polynucleotides and combinatorial libraries of polynucleotides
Inventor: DELAGRAVE SIMON
IPC: C12Q1/68
Filed: 2002-03-20
Abstract: A method of preparing a polynucleotide having a target sequence from a plurality of oligonucleotides, the method comprising: (a) coupling the oligonucleotides to form a plurality of coupled oligonucleotides, wherein each of the coupled oligonucleotides represents a region of the polynucleotide and shares at least one terminal region of sequence with at least one other coupled oligonucleotide; and (b) assembling the polynucleotide by extension of the coupled oligonucleotides; a library of polynucleotides prepared by the method; a method of preparing a polynucleotide having a target sequence from a plurality of oligonucleotides; and a method of identifying a polynucleotide with a predetermined property.
Patent NZ-533130-A (NZ)
Title: Pyrimidine derivatives as modulators of insulin-like growth factor-1 receptor (IGF-I)
Inventor: BARLAAM BERNARD
IPC: A61P35/00
Filed: 2002-12-03
Abstract: Disclosed are pyrimidine derivatives of formula (I) wherein the substituents are as defined in the specification. Compounds of the type disclosed are modulators of insulin-like growth factor-1 receptor (IGF-1) and are useful in the treatment of cancer. Also disclosed are processes for the preparation of compounds of formula (I).
Patent NZ-538726-A (NZ)
Title: N-substituted hydromorphones and the use thereof
Inventor: KYLE DONALD J
IPC: C07D489/00
Filed: 2003-09-24
Abstract: Disclosed are compounds of formula I, wherein R is C1-6alkyl. A particular compound disclosed is N-methylhydromorphone. The compounds are used for the manufacture of medicaments for treating, ameliorating or preventing pain.
Patent NZ-538857-A (NZ)
Title: Compositions for the inhibition of protein kinase C alpha for treatment of diabetes mellitus and cardiovascular diseases
Inventor: MENNE JAN
IPC: A61K31/235
Filed: 2003-09-23
Abstract: Use of inhibitors of protein kinase C-alpha (PKC- alpha) in the production of a medicament for the treatment and/or prevention in diabetic retinopathy, diabetic neuropathy and/or diabetic nephropathy is disclosed, wherein said inhibitor is an antibody which reacts with protein kinase C- alpha, in particular a monoclonal or polyclonal antibody, such as a humanized antibody, and wherein said antibody changes the phosphorylation state of protein kinase C- alpha.
Patent NZ-546041-A (NZ)
Title: Suppressing plant pathogens and pests with applied or induced auxins and a metal
Inventor: STOLLER JERRY H
IPC: A01N/
Filed: 2004-08-18
Abstract: Disclosed are methods for inhibiting fungi and bacterial disease on and in plant tissues, or inhibiting the infestation of plants by pests, comprising: applying to seeds or tubers for a plant prior to planting or to roots, foliage, flowers or fruit of a plant after planting an auxin, together with a metal selected from the group consisting of alkaline earth metals, transition metals, boron and mixtures thereof, said auxin applied in an amount effective to inhibit infestation or growth of harmful organisms causing said disease but wherein said amount is insufficient to negatively effect growth of said plant tissues.
Patent NZ-549817-A (NZ)
Title: Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
Inventor: LE NESTOUR ELISABETH
IPC: A61P15/00
Filed: 2005-03-10
Abstract: Disclosed is a medicament for the treatment of benign breast disease other than gyncecomastia or mastalgia, which is a hydroalcoholic composition comprising 4-hydroxy tamoxifen, isopropyl myristate as a penetration enhancer, an aqueous vehicle, an alcoholic vehicle and a gelling agent.
Patent NZ-550345-A (NZ)
Title: Container and carrier system for holding and presenting surgical materials such as bone screws
Inventor: CANDRIAN KARINA
IPC: A61B19/02
Filed: 2004-06-09
Abstract: The disclosure relates to a container (100) comprising a carrier (1) for holding and presenting surgical auxiliary materials (80), in particular screws such as bone screws, in a receiving or mounting position and at least one removable cover (48') that prevents the auxiliary material from coming loose, but allows said surgical material (80) to be individually presented. According to the invention, at least two containers (100) are detachably interconnected by means of the cover (48') and/or the carrier (1).
Patent NZ-550620-A (NZ)
Title: A method for providing resistance to a plant or plant cell comprising modifying a gene or modifying expression of a NDR/NHL protein gene in a plant
Inventor: SCHMIDT EDUARD DANIEL LEENDERT
Filed: 2003-07-17
Abstract: Disclosed is a method for providing resistance to a plant or a plant cell comprising modifying a gene or modifying expression of the gene, wherein the gene is encoding a protein belonging to a signalling complex comprising NDR/NHL protein, or encoding a protein comprising a ligand for the complex.
Patent NZ-552477-A (NZ)
Title: Extended stay-on wound dressing
Inventor: JENSEN JARL B
IPC: A61L15/58
Filed: 2005-03-09
Abstract: A wound dressing has a dressing layer covered by protective cover layer and a release sheet. The dressing has an adhesive composition on a skin-contacting surface. The adhesive composition comprises, by weight, 20% to 60% of a highly water-absorbable material (e.g. hydrocolloid), 5% to 60% of an acrylic hot melt adhesive, 5% to 40% of a tackifier, 5% to 30% elastomers, and 5% to 30% extender. The composition provides extended stay-on capabilities even in the presence of moisture and is removable from the skin without causing great pain.
Patent NZ-554908-A (NZ)
Title: Upright protector
Inventor: CLARKE MURRAY
IPC: A47B55/00
Filed: 2005-10-13
Abstract: A protector 10 for an upright structural member such as the upright of a storage rack, for protection against forklift strike, includes a body having a front portion 12 and opposite side portions 13, 14 that extend from at least part of the front portion to define a channel 19. The protector is locatable over the structural member so that at least a portion of the structural member is received within the channel. In one form, the side portions include an inwardly turned lip that defines a constricted throat of the channel. The protector includes bearing members 23, 24, 25 within the channel on the inside of the front portion of the protector but spaced from the front portion and via which the protector is bolted 50 to the front face of the upright.
Patent NZ-555000-A (NZ)
Title: Particle-size reduction apparatus, and use thereof
Inventor: GREENWOOD ALAN KENNETH
IPC: A61K9/14
Filed: 2005-12-12
Abstract: A sterilisable particle size reduction apparatus, a method of validating the sterility of components of a sterilisable particle size reduction apparatus, and a method of producing a comminuted suspension of particles, is disclosed. The method of producing a comminuted suspension of particles comprises the steps of: (a) subjecting a suspension of particles to a comminution procedure carried out in a sterilised particle-size reduction apparatus, and (b) recovering a suspension of particles of reduced size where the transverse cross-sectional area of the flow passage is in the range of 3.1x104 to 2.8xl05 micrometer2. The particle size reduction apparatus comprises at least one interaction chamber for reducing the particle size of the suspension. The, or each, interaction chamber is provided with a flow passage through which the suspension is forced, and an intensifier for forcing the suspension through the flow passage of the interaction chamber or interaction chambers.
Patent NZ-561265-A (NZ)
Title: Nailable flooring sheet which includes low density additives in cement
Inventor: GLEESON JAMES
IPC: E04B1/14
Filed: 2006-02-15
Abstract: A fibre reinforced cement bound flooring sheet that is suitable for use in domestic wet area flooring. The flooring sheet includes at least one density modifying additive in a quantity sufficient to lower the dry density of the sheet to less than around 1.5 g/cm3 so that the flooring sheet is nailable. The flooring sheet has a bending strength sufficient to withstand a uniformly distributed load of at least 5 kPa when supported at 450mm centres along its length.
Patent NZ-561789-A (NZ)
Title: Improvements relating to graphical user interfaces
Inventor: STEIN MICHAEL LEWIS
IPC: G06F9/44
Filed: 2004-03-24
Abstract: A system is provided for supporting distributed interaction with a user during a diagnosis workflow process for health professionals, the system includes a centrally stored graphical representation of the workflow process, a number of users located remotely from the centrally stored representation and related to each other in a user hierarchy, each user having access to a version of the representation of the workflow process, and referral means provided within each version of the representation to generate a referral message from a referring user. The referral means is arranged to send the referral message to a reviewer in a next higher level in the user hierarchy. The referral means includes response means enabling the reviewer to generate a message and send the message to the referring user. A method for the system is also provided. (62) (62) Divided out of 542521
Patent NZ-563114-A (NZ)
Title: Lock system for electrical connector
Inventor: FULCHER IAN ROBERT
IPC: H05K7/10
Filed: 2007-11-02
Abstract: An electrical plug or socket connector is disclosed. The electrical connector comprises a lock system for locking together two body parts of the connector. The body parts are rotatable relative to one another and rotation in one relative direction couples the two body parts via the lock system. A locking means is provided on the outside of the inner body part and comprises a locking tab for engaging an abutment on the inside of the outer body part to couple the two body parts. An aperture through the outer body part allows for insertion of a tool to depress the locking tab and disengage it from the abutment to allow for uncoupling of the two body parts. A finger tab of the locking means engages the locking tab as it is depressed by the tool to cause it to remain disengaged from the abutment while the two body parts are rotated into the uncoupled position.
Patent NZ-564923-A (NZ)
Title: Polynucleotide marker genes and their expression, for diagnosis of endotoxemia
Inventor: BRANDON RICHARD BRUCE
IPC: C12Q1/68
Filed: 2006-07-07
Abstract: Disclosed is a method for diagnosing the presence of endotoxemia comprising comparing the expression of at least one endotoxemia marker gene in a biological sample to expression of at least one corresponding endotoxemia marker gene in a reference sample lacking endotoxemia. The endotoxemia marker gene is expressed in leukocytes of animals in which laminitis has been induced by carbohydrate overload.
Patent NZ-564968-A (NZ)
Title: Monopersulfate treatment of membranes
Inventor: MULLER HEINZ-JOACHIM
IPC: B01D65/08
Filed: 2006-07-14
Abstract: Disclosed is a method of hydrophilising a porous polymeric membrane to improve the water permeability of said membrane comprising the step of oxidising said porous polymeric membrane with a source of monopersulfate (HSO5-), wherein the polymeric membrane is prepared from a blend of a hydrophobic and a hydrophilic polymer.
Patent NZ-565555-A (NZ)
Title: Pipe coupling with pipe grip ring interacting with outer sleeve to force ring inwardly to grip outer pipe wall more strongly
Inventor: VAN DIJK BEREND JAN
IPC: F16L33/22
Filed: 2006-02-20
Abstract: A pipe coupling has a coupling body (5) having a passage opening, as well as an outer sleeve (6) , which is arranged partially around the coupling body, these two parts together forming a chamber for accommodating a pipe end. The chamber (8) has an insertion opening (10) for the relevant pipe end at the axially outer end in the outer sleeve, and has stop means (9) for limiting the insertion length of the pipe end into the coupling at the axially inner end in the coupling body. The pipe coupling also has a tubular core part (4) which is designed to be accommodated in a pipe end. Outer sleeve 6 has a tapering inner surface so that sleeve 6 is moved in the direction of pipe insertion it interacts with flexible lips of outer grip ring which are circumferentially spaced apart so that an inserted pipe is gripped more strongly about its outer side.
Patent NZ-567124-A (NZ)
Title: Human antibodies against Interleukin-13 and therapeutic uses to treat asthma
Inventor: CAMPBELL EMMA MICHELLE
IPC: A61P37/08
Filed: 2006-10-19
Abstract: Disclosed are human anti-IL-13 binding molecules, particularly antibodies, and methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma. The claimed antibody binds to an epitope located in helix C of human Il-13.
Patent NZ-570106-A (NZ)
Title: Influenza vaccines containing hemagglutinin and matrix proteins
Inventor: BROEKER MICHAEL
IPC: A61K39/145
Filed: 2007-01-26
Abstract: Disclosed is a purified surface antigen or split virion influenza vaccine comprising influenza virus haemagglutinin and a fragment of M1 matrix protein which co-purify, wherein said matrix protein fragment comprises a T cell epitope of said M1 matrix protein and has a molecular weight that is less than or equal to 10kDa, and wherein the composition does not contain ovalbumin.
Patent NZ-571068-A (NZ)
Title: An antibody that can bind human alpha5beta1
Inventor: CHUNTHARAPAI ANAN
IPC: A61K39/395
Filed: 2007-03-21
Abstract: Disclosed is an antibody that can bind human alpha5beta1, wherein the antibody comprises a light chain variable domain and heavy chain variable domain comprising six hypervariable regions substantially corresponding to the six hypervariable regions of the anti-alpha5beta1 antibody produced by the hybridoma deposited as ATCC No. PTA-7421 in the ATCC on March 7, 2006. Also disclosed is the use of the in the manufacture of a medicament for inhibiting angiogenesis and/or vascular permeability in a subject
Patent NZ-577310-A (NZ)
Title: Improved grg23 epsp synthases: compositions and methods of use
Inventor: HEINRICHS VOLKER
IPC: C12N15/82
Filed: 2007-11-20
Abstract: Disclosed is an isolated or recombinant nucleic acid molecule selected from the group consisting of: a) a nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:28, 30, 32, or 34; and, b) a nucleic acid molecule which encodes a polypeptide comprising the amino acid sequence of SEQ ID NO:29, 31, 33, or 35. Also disclosed is a method for conferring resistance to an herbicide in a plant, said method comprising transforming said plant with a DNA construct, said construct comprising a promoter that drives expression in a plant cell operably linked with a nucleotide sequence selected from the group consisting of SEQ ID NO:28, 30, 32, or 34, and regenerating a transformed plant.
Patent NZ-583102-A (NZ)
Title: Injection system with self reseting base station
Inventor: JENNINGS DOUGLAS IVAN
IPC: A61M5/32
Filed: 2008-07-18
Abstract: Disclosed is a reusable auto-injection system that can be reset by connection to a base station to provide easier and safer operation for unskilled users. The injection system comprises an injection device with a syringe comprising a fluid container and a discharge nozzle or needle. A housing is adapted to receive the syringe that is movable between a retracted position in which the syringe is wholly contained in the housing and an extended position in which at least part of discharge nozzle extends out of the housing. A drive and an actuator mechanism of a rechargeable battery or capacitor operated motor connected to the drive connected to the drive having an unactuated state in which it does not act on the drive and an actuated state in which it has acted on the drive and moved the syringe to its extended position and expelled fluid from the fluid container. The trigger mechanism operates to release the actuator mechanism to move the syringe to its extended position and expel fluid from the fluid container. The base station connects to the housing of the injection device and resets the actuator mechanism from its actuated state to its unactuated state when the base station is connected with the housing of the injection device so that further actuation of the actuator mechanism can take place.
Patent NZ-586084-A (NZ)
Title: Tip for an earth working roll with a seperable wear cap
Inventor: MORRIS RAY J
IPC: B02C4/00
Filed: 2009-01-08
Abstract: 586084 A wear cap (40) for a driven roll of an earth working machine is disclosed. The cap comprises a front working portion with a leading surface facing in the direction the wear cap moves with the roll when driven. The cap (40) has a rear cavity (78) that receives a seat (44) of a holder and includes at least one rearward extending rail or groove (68) to receive the other of a rail or groove (66) on the seat (44). A tip assembly for a driven roll including such a wear cap (40), a holder to be attached to the roll and a retainer (111) holding the wear cap to the roll is also disclosed.