baber/WOPTO huggingface dataset:
Patent NZ-737355-A (NZ)
Title: Compounds targeting proteins, compositions, methods, and uses thereof
Inventor: CHAN KYLE
IPC: C07D403/04
Filed: 2016-05-18
Abstract: The present invention provides compounds of Formula (I) as modulators of protein function, to restore protein homeostasis, including cytokine, aiolos, and/or ikaros activity, and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions, such as cytokine-mediated diseases, disorders, and conditions, including inflammation, fibromyalgia, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, inflammatory bowel diseases, Crohn’s disease, ulcerative colitis, uveitis, inflammatory lung diseases, chronic obstructive pulmonary disease, Alzheimer’s disease, and cancer, are provided.
Patent NZ-741681-A (NZ)
Title: Composite closure with support brace and method for making the same
Inventor: SANTINI FEDERICO
IPC: B65D41/04
Filed: 2016-11-10
Abstract: A composite closure lid assembly (300) for a container cap with a closure shell (202) having a closure socket (203) surrounded by a shell wall (206) and a shell end (208). An inner closure (304) is fixed within the closure socket (203). The inner closure (304) includes a closure wall (312) and a closure end (314) forming a closure gap between the shell end (208) and the closure end (314). The closure gap between the closure end (314) and the shell end (208) is bridged by a plurality of support braces or a support brace (316) with a plurality of support elements (318). A method of forming the composite closure is also disclosed.
Patent NZ-742586-A (NZ)
Title: Method, apparatus and system for automatically controlling inspired oxygen delivery
Inventor: GALE TIMOTHY JOHN
IPC: A61M16/12
Filed: 2016-11-10
Abstract: Provided herein is a method for automatically controlling inspired oxygen delivery, including: receiving signals representing a plurality of input oxygen saturation (SpO2) values for a patient; generating control values based on the input SpO2values and a target SpO2value; and generating output inspired oxygen concentration (FiO2) values based on the control values and reference inspired oxygen concentration (rFiO2) values; wherein the control values include: immediate control values, generated based on the input SpO2values, the target SpO2 value, and an immediate gain coefficient; accumulation control values, generated based on the input SpO2values, the target SpO2value, and an accumulation gain coefficient; and predictive control values, generated based on the input SpO2values, the target SpO2value, and a predictive gain coefficient; wherein the immediate gain coefficient is determined based on the rFiO2value; and wherein a non- linear compensation weighting is applied to the accumulation control value based on a predetermined non-linear relationship between partial pressure of arterial oxygen (PaO2) and SpO2.
Patent NZ-754020-A (NZ)
Title: Composition for promoting differentiation of and protecting neural stem cells and method for inducing neural regeneration using same
Inventor: CHOI KANG-YELL
IPC: G01N33/483
Filed: 2017-11-23
Abstract: The present invention relates to a method for inducing neural regeneration comprising administering an MEK 1/2 inhibitor trametinib to a patient in need thereof. In particular, according to the method of the present invention, the MEK 1/2 inhibitor trametinib induces neural regeneration by differentiating neural stem cells into neural cells, protecting neural cells and neural stem cells from beta amyloid-induced cytotoxicity, or both. The present invention also relates to a method for protecting neural cells from loss or damage of neural cells comprising administering an MEK 1/2 inhibitor trametinib. In addition, the present invention relates to a method for preventing or treating neurodegenerative diseases caused by a loss or damage of neural cells, comprising administering the MEK 1/2 inhibitor trametinib to a patient in need thereof.
Patent NZ-756067-A (NZ)
Title: Method for reforming coal ash, and method for producing fly ash for concrete admixture
Inventor: DOI Koota
IPC: C04B18/10
Filed: 2018-02-08
Abstract: This method for reforming coal ash is characterized in that coal ash having a 45μm sieve residue of greater than or equal to 10 mass% is classified, using a forced vortex centrifugal classifier, with conditions that result in the 45 µm sieve residue of the classified coal ash being in the range of 1-8 mass% and an index of classification accuracy (ĸ = d25/d75) becomes 0.6 or more and 0.7 or less.
Patent NZ-775650-A (NZ)
Title: Separated pupil optical systems for virtual and augmented reality and methods for displaying images using same
Inventor: KLUG MICHAEL A
IPC: G02B27/01
Filed: 2016-05-04
Abstract: Disclosed is a method of operating an AR system to display an image viewable by a user’s eyes, the method comprising: tracking, by an eye-tracking subsystem, a position of the user’s eyes; determining, based on the position, a focus depth of the user’s eyes; selecting, from a plurality of light-guiding optical elements, a subset of light guiding-optical elements configured to focus light at a depth plane corresponding to the focus depth of the user’s eyes; producing a plurality of light beams using a subset of sub-light sources of a plurality of sub-light sources, the subset of sub-light sources being configured to illuminate the subset of light-guiding optical elements; and imaging the plurality of light beams through an imaging system and onto the subset of light-guiding optical elements such that the image is generated at the depth plane corresponding to the focus depth of the user’s eyes.
Patent OA-12035-A (OA)
Title: Methods of reducing serum glucose and triglyceridelevels and for inhibiting angiogenesis using substituted indolealkanoic acids.
Inventor: JACOT JORGE
IPC: A61P17/02
Filed: 1999-12-01
Abstract: Disclosed are methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis, the methods comprising administration of substituted indolealkanoic acids to patients in need of such treatment. Also disclosed are such compounds useful in the treatment of angiogenesis, hyperglycemia, hyperlipidemia and chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds.
Patent PT-100950-A (PT)
Inventor: VORBRUGGEN HELMUT
IPC: A61K31/557
Filed: 1992-10-09
Abstract: PCT No. PCT/DE92/00865 Sec. 371 Date Jun. 11, 1993 Sec. 102(e) Date Jun. 11, 1993 PCT Filed Oct. 9, 1992 PCT Pub. No. WO93/07118 PCT Pub. Date Apr. 15, 1993.The invention relates to 9-substituted bicyclo[3.3.0]octane derivatives of formula I,    <IMAGE>  (I)  and their salts with physiologically compatible bases, as well as the  alpha -,  beta - or  gamma -cyclodextrin clathrates, as well as the compounds of formula I encapsulated with liposomes, process for their production and their pharmaceutical use.
Patent PT-103636-A (PT)
Title: Processo para a depuração e recuperação do gás formado em fornos de carbonização de madeira
Inventor: BORDADO JOAO CARLOS MOURA
IPC: C10B3/00
Filed: 2007-01-08
Abstract: O PRESENTE INVENTO DIZ RESPEITO A UM PROCESSO DE DEPURAÇÃO E RECUPERAÇÃO DO GÁS FORMADO EM FORNOS DE CARBONIZAÇÃO DE MADEIRA EM PROCESSOS DE PRODUÇÃO DE CARVÃO VEGETAL. DO PONTO DE VISTA AMBIENTAL O PROCESSO DE CARBONIZAÇÃO DE MADEIRA É CONSIDERAVELMENTE POLUENTE LANÇANDO PARA A ATMOSFERA UM GÁS COM ELEVADO TEOR POLUENTE, CUJA TOXICIDADE NA ATMOSFERA SE ENCONTRA BEM DOCUMENTADA. O PROCESSO QUE AQUI SE DESCREVE É ADEQUADO PARA A DEPURAÇÃO FÍSICA E QUÍMICA DOS GASES DE EXAUSTÃO FORMADOS, PERMITINDO AINDA A SUA RECUPERAÇÃO COMO COMBUSTÍVEL (VISTO SER UM GÁS DE BAIXO PODER CALORÍFICO) SENDO MÍNIMA OU QUASE NULA A QUANTIDADE LANÇADA PARA A ATMOSFERA. O PRESENTE INVENTO COMPREENDE AS SEGUINTES OPERAÇÕES: RECOLHA DO GÁS, REMOÇÃO DE PARTÍCULAS SÓLIDAS, REMOÇÃO DE LÍQUIDOS ARRASTADOS, TRANSPORTE E ARMAZENAGEM DO GÁS.
Patent PT-103754-A (PT)
Title: Placa trocantérica de contenção - compressão
Inventor: MARTINS JOSE MANUEL RODRIGUES
IPC: A61B17/76
Filed: 2007-05-31
Abstract: A PRESENTE PATENTE, REFERE-SE A UM DISPOSITIVO DESIGNADO POR PLACA TROCANTÉRICA DE CONTENÇÃO-COMPRESSÃO (1), QUE PELA SUA FORMA E COLOCAÇÃO EM RELAÇÃO AO OSSO (PARTE DA PLACA FICA INTERNA AO OSSO E OUTRA PARTE FICA EXTERNA AO OSSO), PERMITE O TRATAMENTO DAS FRACTURAS INTER-TROCANTÉRICAS E ALGUNS TIPOS DE FRACTURAS SUB- TROCANTÉRICAS, TENDO A CAPACIDADE DE SERVIR DE BATENTE NO INTERIOR DO OSSO NESTES TIPOS DE FRACTURAS, COMPARATIVAMENTE A UMA CAVILHA, PERMITINDO MANTER O COMPRIMENTO DO COLO DO FÉMUR AO NÍVEL DA ZONA INTER- TROCANTÉRICA HABITUALMENTE COMINUTIVA E FAZER A COMPRESSÃO NECESSÁRIA AO NÍVEL DO FOCO DE FRACTURA.
Patent PT-109301-A (PT)
Title: Conjunto modular para suporte de cargas
Inventor: PAULO JOSÉ LOPES GONÇALVES
IPC: E04B1/00
Filed: 2016-04-07
Abstract: A PRESENTE INVENÇÃO REFERE-SE A CONJUNTOS MODELARES PARA SUPORTE DE CARGAS CONSTITUÍDO POR ESTRUTURAS SUBSTANCIALMENTE TUBULARES OU CILÍNDRICAS (1) UNIDAS COM RECURSO AOS DIFERENTES NÓDULOS DE LIGAÇÃO POSSÍVEIS DE REALIZAR COM A PRESENTE INVENÇÃO, NOMEADAMENTE O NÓDULO ESFÉRICO (S1), O NÓDULO DE LIGAÇÃO DE UMA SAÍDA (T1), O NÓDULO DE LIGAÇÃO DE DUAS SAÍDAS (T2), O NÓDULO DE LIGAÇÃO DE TRÊS SAÍDAS (T3) E O NÓDULO DE LIGAÇÃO DE QUATRO SAÍDAS.
Patent RU-94013573-A (RU)
Inventor: EVTEEV E A
IPC: B21B45/02
Filed: 1994-04-18
Abstract: FIELD: rolling. SUBSTANCE: the offered section has roller conveyor of wire rod coils combined with cooling device made in form of through heat-insulating tunnel with covers provided with means for air supply to its working space in form of forced-draught fans located under roller conveyor. Heat-insulating tunnel is made in form of a row of similar gas-tight sections which are neutral aerodynamically with respect to adjacent volumes and joined with one another. Each section has forced draught fan, means of convective thermostating made in form of closed circulating circuit provided with additional fan, supplying and discharging collectors, electric heater and pipeline of circulating system. Means for convective thermostating of each section have devices for automatic regulation of air temperature in its working space with temperature-sensitive element, remote temperature controller and multiposition switch, all installed in circuit of electric heater. The offered wire rod cowling section allows direct air patenting of wire rod from rolling heat, practically of any grade of steel in process of rolling mill operation. EFFECT: extended technological capabilities of wire rod cooling section in production of wire rod of wide range of grades, excluded patenting in metalware shops, and improved ecological conditions in the region of works. 23 cl, 1 dwg
Patent RU-94021680-A (RU)
Inventor: GVOROV G V
IPC: B01J19/00
Filed: 1994-06-08
Abstract: FIELD: chemical technology, may be used to obtain synthetic products, for instance, ammonium, methanol, hydrocarbon, acetic and formic acids, etc. SUBSTANCE: device for obtaining synthetic products has apparatuses for processing initial raw materials, device for cooling generating volatile products, compressor and synthesis column. Apparatuses for processing initial raw materials are made in the form of two or more metallurgical furnaces, for example, inductive furnaces equipped with nozzles with inlet valves for initial raw products and outlet valves for generating volatile products. Beds of melted ferrous oxide or magnetic ferric oxide are placed on furnace hearths. The beds are agitated using devices for electromagnetic agitation. The furnaces are operated alternately in processing initial raw materials with ferrous oxide melt, and recovering magnetic ferric oxide melt being formed. Both furnaces are additionally provided with oxygen outlet nozzles, cooling devices and compressor or vacuum-pump. EFFECT: high productivity. 1 cl, 1 dwg
Patent RU-94023681-A (RU)
Title: Root cutter
Inventor: VOROZHEJKIN G G
IPC: A01B35/22
Filed: 1994-06-22
Abstract: FIELD: agricultural engineering; devices for undercutting roots of forest culture seedlings. SUBSTANCE: root cutter has frame 1, belt cutting member 10 whose ends are secured on corresponding sliders 8 installed on guides 9 connected with frame 1, and mechanism to provide reciprocation of belt cutting member over circumference which has drive shaft and crank 5. Novelty in design of root cutter is that rocker 2 is installed on frame 1. Slots 6 are made on external ends of rocker 2. Rollers 7 secured on corresponding sliders 8 are arranged in slots 6. Rocker 2 is connected with crank 5 of drive shaft by means of lever 3 and connecting rod 4. EFFECT: improved operating characteristics. 1 dwg
Patent RU-94025122-A (RU)
Inventor: KOSTYLEV A D
IPC: E02F5/18
Filed: 1994-07-04
Abstract: FIELD: building equipment. SUBSTANCE: ground-taking tank with attached percussion mechanism is provided with automatic lever-hinge stepped feeder interacting with walls of the pipe being laid down when the device is in motion. EFFECT: increased productivity.
Patent RU-94027772-A (RU)
Inventor: BLIZNJUK N K
IPC: C07F9/145
Filed: 1994-07-25
Abstract: FIELD: organic chemistry. SUBSTANCE: product: mono-(aroxycarbonyl)-arylphosphites (I) of the formulawhere A - unsubstituted or substituted arylene and Ar - unsubstituted or substituted aryl. Method is based on the combined interaction of phosphorus trichloride, phosphorous acid and corresponding hydroxyarylcarboxylic acids and phenol at the mole ratios 2:1:3:3, respectively. Process is carried out by phosphorus trichloride addition to the suspension of other reagents in organic solvent, for example, in toluene and terminated at reaction mass boiling point up to hydrogen chloride evolution ceasation. The end products were isolated by the known procedures and at quantitative yield practically. They are colorless oils or paraffin-like solid products. For reaction acceleration catalyst can be used that is taken from the group of heterocyclic bases (for example, pyridine), quaternary ammonium or phosphonium compounds or transient metal salts. The following compounds (I) were synthesized (A, Ar, physical properties, empirical formula): CH-1,2, CH, n= 1.5720, d= 1.3264, CHOP; CH-1,4, CH, decomposition point is 200-230 C, CHOP; 6--CHCH-1,2, CH, softening point is 115-120 C, CHOP; 6--CHCH-1,2, 4-CHCH, softening point is 125-130 C, CHOP. (I) are semiproducts used for synthesis of bioactive compounds and as fungicides, bactericides and drugs. EFFECT: improved method of synthesis.
Patent RU-94032306-A (RU)
Inventor: ZENIN V V
IPC: G01N27/02
Filed: 1994-09-05
Abstract: FIELD: material testing; may be used in atomic power engineering, aviation and space technology, in petroleum and chemical industries, in shipbuilding and other branches of industry. SUBSTANCE: method consists in cementing of measurement element at certain distance on tested section. In the capacity of measurement sensitive element there are used current carrying wires applied through dielectric film in the form of mesh of film metallization. Their break with emergence of crack is fixed by indicator in the form of light, sound or other signal. Value and direction of crack are judged by break. EFFECT: enhanced authenticity of method. 2 cl, 2 dwg
Patent RU-94037343-A (RU)
Inventor: AFANAS EV N D
IPC: C22C38/58
Filed: 1994-10-04
Abstract: FIELD: metallurgy, namely, production of refractory steels that may be used at making centrifugal tubes designed for coils of tubular furnaces, rollers and other parts working in aggressive media upon high temperature and pressure values. SUBSTANCE: refractory austenitic steel including carbon, silicium, manganese, nickel, chrome, nitrogen, also contains zirconium at predetermined relation of ingredients (mass%). EFFECT: elimination of steel cracking under loading, enhanced strength characteristics and therefore high-quality centrifugal tubes with increased manufacturing degree, enhanced operating properties.
Patent RU-94041642-A (RU)
Inventor: VAGNER E A
IPC: A61B5/0245
Filed: 1994-11-18
Abstract: FIELD: medicine; cardiology. SUBSTANCE: electrocardiogram is registered while a tested patient is under physical load. Individual frequency curve is registered additionally, calculated in synchronism with load, by means of the device equipped with biological detector. Real electrocardiogram of tested patient is registered by autonomous registrar. If real maximal frequency of systole of heart's chambers is detected to be lower than frequency of heart systole, calculated by biological detector, insufficiency of chronotropic function of heart is determined. EFFECT: enhanced accuracy of method.
Patent RU-95100761-A (RU)
Inventor: BERNAR BOKEHJ
IPC: A61K8/42
Filed: 1995-01-10
Abstract: FIELD: cosmetics. SUBSTANCE: invention relates to new detergent compositions for hair (shampoo) containing at least one anionic surface-active agent, at least one amphoteric surface-active agent of imidazoline type and at least one conditioning agent, and at least 2 weight % (of total composition weight) one carboxylic acid that has hydroxyl radical at alpha-position, or its derivatives. Composition is designed for sensitive hair. EFFECT: enhanced quality of composition.
Patent RU-95103388-A (RU)
Inventor: SOKOLOV A G
IPC: H01L27/20
Filed: 1995-03-07
Abstract: FIELD: manufacture of integrated-circuit microdisplacement transducers, electronic safety systems for transport, navigations system and moving-object observing facilities. SUBSTANCE: microdisplacement transducer is sensing element made in the form of cantilever within semiconductor material substrate with seismic masses and additional semiconductor substrate with photosensing elements formed within its material and arranged along displacement of sensing element. EFFECT: improved design. 1 cl, 2 dwg
Patent RU-95103505-A (RU)
Inventor: IVASHINA A I
IPC: A61F9/00
Filed: 1995-03-10
Abstract: FIELD: medicine; surgery; ophthalmology. SUBSTANCE: method involves evaluation of clinical refraction, cornea diameter, age, absolute volume of accommodation, eye-to-object distance for maximum length of the patient's work, calculation of the coagulation beams from an empirical formula, and thermal keratocoagulation using the calculated characteristics. EFFECT: simpler and more effective method.
Patent RU-95105702-A (RU)
Inventor: EMEL JANOV A A
IPC: G02B5/22
Filed: 1995-04-13
Abstract: FIELD: IR filters. SUBSTANCE: invention refers to filters reflecting infrared radiation (thermal radiation) mounted for illumination, heating and protection of premises, greenhouses, etc, from overheating with solar energy. It enables constancy of light transmission within visible region of spectrum to be ensured. This is achieved by injection of dispersive filter of vanadium dioxide into binder. It is advantageous to inject filling agent in the form of particles of ball shape having diameter 0.5 μ < d < 50.0 m. EFFECT: improved overheating protection. 2 cl, 1 dwg
Patent RU-95106102-A (RU)
Inventor: ZABEGAEV A I
IPC: F03D7/04
Filed: 1995-04-20
Abstract: FIELD: wind power engineering. SUBSTANCE: wind-electric power plant has tower, windwheel, multistage step-up gear drive, flywheel, coupling, synchronous generator, and control system. It is provided with coupling device incorporating disengageable coupling, brake, additional shaft; large gear of intermediate shaft is coupled with one main and one additional high-speed shafts one of which is hollow and joined with disengageable coupling whose central output member is coupled through additional shaft passed inside hollow output shaft of step-up gear drive with flywheel mounted on other end step-up gear drive relative to disengageable coupling; other high-speed additional shaft is coupled with controlled brake. Novelty is that brake and coupling device are mounted on step-up gear drive housing on side opposite to generator and windwheel; brake may be of mechanical, shoe, disk, or electromagnetic type. Disengageable coupling is friction, single- or multiple-disk design incorporating unit for adjusting axial thrust for compressing the disks; pressure member of coupling is directly linked with drive mechanism. Disconnecting drive of coupling is built up of series-connected motor, reduction unit, and screw-nut pair wherein the screw is joined with reduction unit output shaft and nut is hinged to pressure member of disengageable coupling; optional design has screw-nut pair built as integral unit hinged on coupling case and pressure member is made in the form of lever hinged with coupling pusher. EFFECT: provision for trouble-free operation of wind-electric power plant due to releasing power flow in case of power fluctuations in transmission, improved reliability and safety in operation due to remotely engageable braking mechanisms, reduced size of gondola and material input due to compact arrangement of transmission and power- generating equipment within plant gondola, reduced loads acting on parts and nuts, increased service life of plant. 13 cl, 4 dwg
Patent RU-95109931-A (RU)
Inventor: DANIEL SHTAJNER
IPC: B60M1/24
Filed: 1993-10-13
Abstract: FIELD: transport engineering. SUBSTANCE: device has connecting device 17, 18 fixed to the load-carrying rope 10 and connecting member 16 that is insulated from the load-carrying rope and used for connecting contact wire 14 by means of gripping member 25. Connecting member 16 is made of insulating plastic, preferably of polyamide reinforced with fiber glass, and forms a united shaped body together with at least one portion 17 of connecting device 17,18. The shaped body has a socket for receiving load-carrying member 20 that allows the member to be adjusted with respect to the socket. Connecting member 16 has load-carrying shoe 17 provided with a connecting lug for fixing insert 32 of load-carrying member 20 inside it and clamping cover 18 coupled with load- carrying shoe by screwing them together. Load-carrying shoe 17 and/or clamping cover 18 are provided with a longitudinal groove for receiving current-carrying rope 10 without slipping. EFFECT: enhanced reliability.
Patent RU-95112462-A (RU)
Inventor: MURDOK DUGLAS S
IPC: C12R1/19
Filed: 1993-09-30
Abstract: FIELD: molecular biology. SUBSTANCE: invention relates to DNA molecules encoding β-subunit of the modified tryprophan synthase. These polypeptide analogs at their expression in recombinant host-microorganism promote the producing and accumulation of significant levels of intracellular indole. Indole produced by this method in the presence of aromatic dioxygenase can be converted to indoxyl that is oxidized to indigo on air. EFFECT: improved method of indole biosynthesis.
Patent TW-200304510-A (TW)
Title: Process for manufacturing polypropylene monofilaments, polypropylene monofilaments and their use
Inventor: SCHUTZE GUSTAV
IPC: D01F6/46
Filed: 2002-12-04
Abstract: In a process for manufacturing monofilaments of a polypropylene having a melt flow index (MFI) at 230 DEG C / 2.16 kg of 2 to 16 g/10 min and possessing a diameter of greater than 0.050 mm and an improved abrasion resistance, from 20 to 0.1% by weight of an additive is added to the polypropylene upstream of the extruder, the melt is spun into a water bath, drawn into monofilaments and the monofilaments are wound up. The monofilament of a polypropylene having a melt flow index (MFI) at 230 DEG C / 2.16 kg of 2 to 16 g/10 min and possessing a diameter of greater than 0.050 mm and an improved abrasion resistance has a strength of at least 50 cN/tex for an elongation corresponding to the maximum tensile stress (elongation at break) of less than 30%. It also has an abrasion of less than 0.05% and a relative fracture energy > 100% after treatment for 24 hours at 120 DEG C.