baber/WOPTO huggingface dataset:
Patent MX-2018009227-A (MX)
Title: G protein-coupled receptor (gpcr) modulation by imipridones.
Inventor: MARTIN STOGNIEW
IPC: C07K14/72
Filed: 2017-01-30
Abstract: Imipridones has been found to selectively modulate Class A G protein-coupled receptors (GPCRs), such as the D2-like subfamily of dopamine receptors, and to be useful for the treatment of conditions and disorders in need of such modulation, such as cancers, psychiatric disorders, and bacterial infections. In addition, methods of identifying whether a subject having these condition, is likely to be responsive to a treatment regimen, such as administration of an imipridone, are provided. Furthermore, methods of assessing the effectiveness of a treatment regimen, such as administration of an imipridone, monitoring, or providing a prognosis for a subject with these condition are also provided.
Patent MX-2018016091-A (MX)
Title: Phospholipid compositions.
Inventor: COLLEEN HUDSON
IPC: A61K31/683
Filed: 2017-06-29
Abstract: Compositions involving a modified egg yolk extract for use as an effective anti-cancer agent are described. The modified egg yolk extract involves specific fractions of phosphatidylcholines and sphingomyelins modified and produced from a chemical synthesis applied to the extract that produce a beneficial effect on the inhibition of cancerous cell growth. Methods of administering these compositions are also described.
Patent MX-2019000214-A (MX)
Title: Detection of surface irregularities in coins.
Inventor: Serge LEVESQUE
IPC: G06T7/62
Filed: 2017-06-22
Abstract: Detection of surface irregularities in coins. Three-dimensional topographic data of at least one surface of a coin, having at least one feature, is acquired and used to determine characteristics of the coin features, based on vector components of normal vectors at various points on the surface of the coin. The feature characteristics are then compared to reference feature characteristics. Based on this comparison, an irregularity indication is provided if differences between the feature characteristics and the reference characteristics are found.Detection of surface irregularities in coins. Three-dimensional topographic data of at least one surface of a coin, having at least one feature, is acquired and used to determine characteristics of the coin features, based on vector components of normal vectors at various points on the surface of the coin. The feature characteristics are then compared to reference feature characteristics. Based on this comparison, an irregularity indication is provided if differences between the feature characteristics and the reference characteristics are found. A refrigeration system for cooling a refrigeration compartment. The refrigeration system comprises a cooling reservoir for cooling refrigerant in a first loop using energy recovered from an engine exhaust stream and a refrigeration circuit comprising a compressor drivable by an internal combustion motor, the compressor circulating refrigerant in a second loop. The refrigeration system comprises at least one heat exchanger in communication with the first and second loops to receive cooled refrigerant, and at least one blower for forcing air over the at least one heat exchanger. A controller selectively activates the internal combustion motor based on a temperature of the cooling reservoir.
Patent MX-2019001149-A (MX)
Title: Method of generating aerosol.
Inventor: JEREMY PHILLIPS
IPC: A24D1/20
Filed: 2017-07-25
Abstract: Provided herein is a method of generating aerosol from an aerosol-generating substrate using an aerosol-generating device with at least one heat source disposed to heat, but not burn, the aerosol-generating substrate in use. The aerosol-generating substrate has first and second portions having substantially the same composition, and/or has first and second portions and there is no physical separation between the portions. The method includes heating the aerosol-generating substrate in the aerosol-generating device, so that a temperature profile of the first portion of the aerosol-generating substrate during heating is different from a temperature profile of the second portion of the aerosol-generating substrate.
Patent MX-2019003002-A (MX)
Title: Combination therapies using indazolylbenzamide derivatives for the treatment of cancer.
Inventor: EVERARDUS O M ORLEMANS
IPC: A61K31/436
Filed: 2017-09-25
Abstract: The invention relates to combination therapies useful in the treatment and/or prevention of cancer.
Patent MX-2019003646-A (MX)
Title: System and method for performing alternative and sequential blood and peritoneal dialysis modalities.
Inventor: JUSTIN BELANGER ROHDE
IPC: A61M1/28
Filed: 2015-09-11
Abstract: A dialysis system (10a) includes: a dialysis fluid pump receptacle (64) actuated by a dialysis fluid pump actuator; a dialysis fluid line (70); a blood filter (40) in fluid communication with the dialysis fluid pump receptacle via the dialysis fluid line; an extracorporeal circuit (16); a blood pump receptacle (30a, 30b) actuated by a blood pump actuator and in fluid communication with the blood filter via the extracorporeal circuit; and a control unit (50) that (i) in a first treatment pumps peritoneal dialysis fluid through the dialysis fluid pump receptacle, the dialysis fluid line, the blood filter, the extracorporeal circuit and the blood pump receptacle to the patient's peritoneum operating the dialysis fluid pump actuator and the blood pump actuator at a first pressure, and (ii) in a second treatment pumps blood through the extracorporeal circuit, the blood pump receptacle and the blood filter operating the blood pump actuator at a second, different pressure.
Patent MX-2019004701-A (MX)
Title: Method for inhibiting corrosion in the crude distillation process.
Inventor: CARRILLO SALGADO IRENE
IPC: C23F11/00
Filed: 2019-04-05
Abstract: The present invention relates to a method of protection against corrosion in refining process units of crude oil contaminated with organic chlorides through the application of anticorrosive compounds, based on rare earth salts. Said salts include neodymium and praseodymium salts, used as additives, with the distinctive element of being nitrogen-free and suitable for service at high temperatures, designed to extend the useful life of facilities and processes associated with oil refining and the petrochemical industry.
Patent MX-2019005640-A (MX)
Title: Near field communication for a tobacco-based article or package therefor.
Inventor: RAJESH SUR
IPC: A24F40/65
Filed: 2017-11-15
Abstract: An apparatus embodied as a tobacco-based article including a consumable material that is tobacco, or that is made, derived from or incorporates tobacco, or as a package for one or more of the tobacco-based article or the consumable material, includes a housing and near field communication (NFC) tag. The housing is structured to retain the tobacco-based article or the consumable material. The NFC tag is configured to store or generate information related to the article or the material. The NFC tag is coupleable with a NFC reader to enable wireless transfer of the information to a computing device to enable authentication of the apparatus, or display or storage of the information, at the computing device or a service platform in communication with the computing device.
Patent MX-2019007649-A (MX)
Title: Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides.
Inventor: YIMIN QIAN
IPC: A61K31/4375
Filed: 2017-12-22
Abstract: The present disclosure relates to bifunctional compounds, which find utility as modulators of Rapidly Accelerated Fibrosarcoma (RAF, such as c-RAF, A-RAF and/or B-RAF; the target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a Von Hippel-Lindau, cereblon, Inhibitors of Apotosis Proteins or mouse double-minute homolog 2 ligand which binds to the respective E3 ubiquitin ligase and on the other end a moiety which binds the target protein RAF, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein, or the constitutive activation of the target protein, are treated or prevented with compounds and compositions of the present disclosure.
Patent MX-2019007762-A (MX)
Title: Systems and methods for correction of geographic inconsistency in item properties.
Inventor: SEAN PAUL REAL
IPC: G06Q30/02
Filed: 2016-11-04
Abstract: Methods, systems, and non-transitory computer readable media are correction of geographic inconsistency in item properties. A system identifies locations of interest based on a location of a mobile device and acquires item-descriptive and item-property data associated with an item at the location of interest. The system connects to a secure network to identify a corresponding item and retrieve corresponding item-property data associated with the corresponding item from a secure item database server. The system determines a difference between the corresponding item-property data and the item-property data and updates the secure item database server based on the difference.
Patent MX-2019008262-A (MX)
Title: Bench top board scoring device.
Inventor: WILLIAM J RAGO
IPC: B26D7/00
Filed: 2018-01-26
Abstract: A bench top board scoring device (10) is provided, including a frame (14) having a first end (16) and an opposite second end (18), a work area (20) defined between the first and second ends (16, 18), each end (16, 18) having at least one leg (22) configured for contacting a substrate (12). A track (36) is connected to the frame (14) and extends between the first end (16, 18, 38) and the second end (16, 18, 38), a carriage (42) is slidably mounted to the track (36) for travel between the first end (16) and the second end (18), and an arm (50) has an upper surface (52), a pivot end (54) pivotally connected to the carriage (42), and an opposite knife mount end (56). A knife blade (78) is mounted to the knife mount end (56). Wherein the present device (10) is constructed and arranged so that as the carriage (42) is moved from the first end (16) to the second end (18), wallboard samples placed in the work area (20) and contacted by the knife blade (78) receive a constant scoring force.
Patent MX-2019008675-A (MX)
Title: Hydroxysteroid 17-beta dehydrogenase 13 (hsd17b13) variants and uses thereof.
Inventor: OMRI GOTTESMAN
IPC: C12Q1/6883
Filed: 2018-01-19
Abstract: Provided are compositions related to HSD17B13 variants, including nucleic acid molecules and polypeptides related to variants of HSD17B13, and cells comprising those nucleic acid molecules and polypeptides. Also provided are methods related to HSD17B13 variants. Such methods include methods for detecting the presence of the HSD17B13 rs72613567 variant in a biological sample comprising genomic DNA, for detecting the presence or levels of any one of variant HSD17B13 Transcripts C, D, E, F, G, and H, and particularly D, in a biological sample comprising mRNA or cDNA, or for detecting the presence or levels of any one of variant HSD17B13 protein Isoforms C, D, E, F, G, or H, and particularly D, in a biological sample comprising protein. Also provided are methods for determining a subject's susceptibility to developing a liver disease or of diagnosing a subject with liver disease.
Patent MX-2019008725-A (MX)
Title: Systems and methods for enhancing trichome formation and density in cannabis.
Inventor: SAYRE RICHARD
IPC: C12N15/84
Filed: 2019-07-23
Abstract: The present invention includes systems, methods and compositions for increasing trichome formation and/or density in cannabinoid producing plants, such as Cannabis and hemp. Additional aspects of the invention further include systems, methods and compositions for increasing cannabinoid and terpene biosynthetic and storage capacity in Cannabis.
Patent MX-2019010329-A (MX)
Title: Characterisation of emulsion stability.
Inventor: BØRRE TORE BØRRESEN
IPC: G01N27/04
Filed: 2017-03-01
Abstract: A method of assessing the effect of a production chemical on the stability of a water and oil emulsion, the emulsion comprising the production chemical, is provided. The method comprises: applying a potential difference across the emulsion at a detection site; measuring a current flowing through the emulsion due to the applied potential difference; and using this measured current to assess the effect of the production chemical. The step of using the measured current to assess the effect of the production chemical may comprise determining, based on the measured current, whether a critical potential of the emulsion has been reached or exceeded. The emulsion may be a crude oil emulsion. It may be a water-in-oil emulsion. The production chemical may be an emulsion breaker. Also provided is an apparatus for assessing the effect of a production chemical on a water and oil emulsion.
Patent MX-2019010802-A (MX)
Title: Anti-par2 antibodies and uses thereof.
Inventor: DAVID FAIRMAN
IPC: A61P25/00
Filed: 2018-03-16
Abstract: The present disclosure provides antibodies and antigen-binding fragments capable of binding PAR2. In some embodiments, the anti-PAR2 antibodies or antigen-binding fragments thereof bind PAR2 in a pH-dependent manner. The disclosure further provides methods for making and using the antibodies and antigen-binding fragments.
Patent MX-2019013180-A (MX)
Title: Filter subassembly, filter assembly, filter and method for utilizing the same.
Inventor: MARK A ROLL
IPC: B01D27/08
Filed: 2016-03-28
Abstract: A filter subassembly is disclosed. The filter subassembly includes an end cap connected to a ring of memory material. The end cap includes a tube-shaped body, a first ring-shaped body, a second ring-shaped body and a third ring-shaped body. The tube-shaped body is defined by an inner radial surface, an outer radial surface, a first axial surface and a second axial surface. The inner radial surface defines a passage extending through the tube-shaped body. The first ring-shaped body extends axially away from the first axial surface of the tube-shaped in a first axial direction. The second ring-shaped body extends axially away from a second axial surface of the tube-shaped body in a second axial direction that is opposite the first axial direction. The third ring-shaped body extends axially away from the second axial surface of the tube-shaped body in the second axial direction that is opposite the first axial direction. Each of the first ring-shaped body, the second ring-shaped body and the third ring-shaped body are defined by an inner radial surface, an outer radial surface and an axial surface that connects the inner radial surface to the outer radial surface. One or both of the first axial surface of the tube-shaped body and the inner radial surface of the first ring-shaped body is disposed adjacent the ring of memory material. The second axial surface of the tube-shaped body, the inner radial surface of the second ring-shaped body and the outer radial surface of the third ring-shaped body collectively define a ring-shaped filter media receiving channel. A filer assembly is also disclosed. An assembly is also disclosed. A filter is also disclosed. A method is also disclosed.
Patent MX-2019013601-A (MX)
Title: Method for extracting protein, starch and fiber from buckwheat.
Inventor: JOVIN HASJIM
IPC: C08B30/04
Filed: 2018-05-14
Abstract: The present invention relates to a method for extracting protein, starch and fibers from buckwheat, more particularly from buckwheat groat or flour.
Patent MX-2019014167-A (MX)
Title: Recombinant immunogens for the production of antibodies against toxic enzymes and as viper antivemom.
Inventor: CORRALES GARCÍA Ligia Luz
IPC: C12N15/63
Filed: 2019-11-27
Abstract: The present invention refers to the use of the primary structures of three proteins from the venomous gland of the viper species Bothrops ammodytoides called rBamPLA2_1 (SEQ. ID NO: 1), rBamSP_1 (SEQ. ID NO: 2) and rBamMP_1 (SEQ. ID NO: 13), which were obtained from known sequences of their N-terminals and through the use of molecular biology, to use them as a basis to generate new immunogens to produce antibodies in order to be used to detect and/or neutralize the activity of phospholipases, serinoproteases and/or metalloproteases, both in isolation and as part of the poisons of species of the genus Bothrops. The invention also relates to new recombinant immunogens based on such sequences: HisrBamPLA2_1 (SEQ. ID NO: 3), the fragment of HisrBamSP_1 (SEQ. ID NO: 4), and HisrBamMP_1 (SEQ. ID NO: 14); to the fragment of cDNA_HisrPLA2_1 (SEQ. ID NO: 5), to the fragment of cDNA_HisrBamSP_1 (SEQ. ID NO: 6), and to the fragment of cDNA_HisrBamMP_1 (SEQ. ID NO: 15), the latter three encoding said proteins, a the expression construct for said fragments, as well as the bacterial cells transformed with said constructs and the method to produce the proteins HisrBamPLA2_1 (SEQ. ID NO: 3), HisrBamSP_1 (SEQ. ID NO: 4) and HisrBamMP_1 (SEQ. ID NO: 14) by recombinant DNA techniques. These proteins are useful as immunogens for the production of antibodies against phospholipases and serinoproteases, which can enrich antivenoms, or for the recognition of said enzymes in venoms of vipers of the genus Bothrops. It also refers to the polyclonal antibodies against phospholipases and serinoproteases of Bothrops venom and to the serotherapeutic and phabotherapeutic agents obtained from said antibodies and to the pharmaceutical compositions of the respective antibodies.
Patent MX-2019015503-A (MX)
Title: Compositions and method for reducing cardiotoxicity.
Inventor: BOUCHARD ANNIE
IPC: A61K39/395
Filed: 2018-07-06
Abstract: The present invention includes composition and methods for inhibiting or decreasing impaired systolic ejection fraction associated with cardiotoxic therapeutic treatment in a subject receiving a cardiotoxic chemotherapeutic agent causing impaired systolic ejection fraction comprising: identifying a subject in need of cardioprotection from the therapeutic treatment; and delivering an effective amount of a phospholipid or derivatives thereof that is cardioprotective to the heart of the subject thereby inhibiting or decreasing impaired systolic ejection fraction associated with administration of the cardiotoxic chemotherapeutic treatment to the subject.
Patent MX-2020005619-A (MX)
Title: Method for treating lignocellulosic biomass.
Inventor: AYMARD CAROLINE
IPC: C08H8/00
Filed: 2018-12-04
Abstract: The invention concerns a method for treating lignocellulosic biomass, said method comprising the following steps: a. Preparing an impregnation liquor (4) containing a chemical catalyst intended to impregnate the biomass b. Introducing the crushed biomass (6) through an inlet of an impregnation reactor (5), said inlet being situated in a first impregnation area (5a) of said impregnation reactor that comprises two superposed areas, said first impregnation area and a second so-called dewatering area (5b) above the impregnation area c. Introducing the liquor (4a) through a first liquor inlet situated in said first impregnation area (5a) of the reactor, d. Introducing said liquor (4b) into said reactor through a second liquor inlet in another area of the reactor (5d) situated below the biomass inlet in the first impregnation area (5b). The invention also concerns the facility for implementing the method.
Patent MX-2020006130-A (MX)
Title: Gas deficiency recovery determination method for hybrid vehicle, and vehicle control device for same.
Inventor: FUJITA YUKI
IPC: B60W10/08
Filed: 2017-12-15
Abstract: A gas deficiency recovery determination method carried out after a gas deficiency determination has taken place, wherein: when driving of a hybrid vehicle is to be started, speed control of a power generator 50 is performed for a prescribed duration and then stopped; if the state in which the subsequent speed Î² of the engine 40 is higher than a threshold value remains detected beyond a first determination duration T<sub>A</sub>, it is determined that a gas deficiency recovery has taken place; and if the measured duration does not exceed the first determination duration, measurement of the duration for which the speed of the engine is less than the threshold value is commenced, whereupon if the measured duration exceeds a second determination duration, the gas deficiency determination is maintained.
Patent MX-2020006484-A (MX)
Title: Bogie frame for rail vehicles made from an aluminum casting.
Inventor: THONI LOTHAR
IPC: B61F5/52
Filed: 2018-12-17
Abstract: The invention relates to a bogie frame (1) for rail vehicles having at least two wheelsets, the bogie frame comprising two longitudinal members (3), which extend parallel to each other over axle bearings, one or more cross-members (2) connected to the longitudinal members (3), and a holding region (5) for functional elements, the bogie frame (1) being produced completely as a casting of an aluminum alloy in a sand casting process, said casting having a hollow profile, which has cavities (10) in the interior and is stabilized by means of ribs (8, 9). The invention further relates to a method for producing a bogie frame of this type and to a rail vehicle equipped with a bogie frame of this type.
Patent MX-2020006663-A (MX)
Title: Solid delivery composition.
Inventor: LONGO LUIGI MARIA
IPC: C07K16/24
Filed: 2018-12-20
Abstract: The present invention provides an innovative combination of biomaterials, multifunctional polymers, able to structure themselves at the site of action.The innovative combination of biomaterials of the invention is formulated in a solid composition and can be used as a versatile delivery vehicle or carrier in many pharmaceutical fields. The solid composition comprising the combination of biomaterials of the invention is provided to target delivery for medical purposes in humans.
Patent MX-2020008355-A (MX)
Title: Composite elements of thermal insulation material, adhesive and outer layer.
Inventor: JACOBMEIER OLAF
IPC: C09J175/08
Filed: 2019-01-30
Abstract: The present invention relates to a method for producing composite elements comprising thermal insulation material (B), adhesive (C), and optionally at least one outer layer (A), by bonding the thermal insulation material (B) with the adhesive (C), wherein the adhesive (C) is a polyurethane adhesive preparable by mixing polyisocyanates (a) with polyols (b) having at least two isocyanate-reactive groups, blowing agents (c), comprising water, and optionally chain extenders (d), catalysts (e), and other auxiliaries (f), where the polyols (b) comprise polyetherols and the polyetherols comprise 50 to 90 wt% of at least one polyalkylene oxide (b1) having a hydroxyl number of 120 to 300 mg KOH/g, based on a difunctional starter molecule, and an ethylene oxide fraction, based on the alkylene oxide content, of 60 to 100 wt%, and a fraction of primary OH groups of 50% to 100%, 10 to 50 wt% of at least one polyalkylene oxide (b2) having a hydroxyl number of 120 to 600 mg KOH/g, based on a difunctional and/or a trifunctional starter molecule, and an ethylene oxide fraction, based on the alkylene oxide content, of 0 to 40 wt%, and 0 to 30 wt% of at least one further polyalkylene oxide (b3) having a hydroxyl number of 100 to 800 mg KOH/g, based on a di- to tetrafunctional starter molecule, based in each case on the total weight of components (b1) to (b3). The present invention further relates to composite elements composed of thermal insulation material (B) and adhesive (C) and also, optionally, at least one outer layer (A), which are producible by such a method, and also to the use of the adhesive (C) for bonding thermal insulation materials (B).
Patent MX-2020009870-A (MX)
Title: Histone deacetylase inhibitors.
Inventor: JACQUES VINCENT
IPC: C07D205/06
Filed: 2015-09-11
Abstract: Proivded herein are compounds and methods for inhibiting histone deacetylase ("HDAC") enzymes (e.g., HDACl, HDAC2, and HDAC3).