baber/WOPTO huggingface dataset:
Patent CA-2640087-A1 (CA)
Inventor: BATTISTA MICHELA
IPC: A61K31/138
Filed: 2007-01-25
Abstract: Methods and compositions for modulating the mobilization of stem cells, particularly for promoting or increasing the mobilization of hematopoietic stem cells from the bone marrow to the peripheral blood are disclosed. In particular, the invention relates to the use of adrenergic agonists that act in concert with a mobilization compound or agent. The mobilization agent(s) may act to decrease the expression or function of the chemokine, CXCL 12, or may act to block or antagonize CXCR4. The invention also relates to methods of using these compounds or agents for enhancing the mobilization of hematopoietic stem cells when harvesting of the stem cells is necessary for the treatment of diseases, disabilities or conditions whereby transplantation of such cells would be beneficial in ameliorating the symptoms associated with such diseases, disabilities or conditions. Methods of screening for novel agents and pharmaceutical compositions comprising these agents are also disclosed.
Patent CA-2641105-A1 (CA)
Title: Cannulated suture anchor system
Inventor: LEHMAN RICHARD C
IPC: A61B17/04
Filed: 2006-03-09
Abstract: A system and associated method for arthroscopic repair is particularly adapted in reattaching a ligament and/or tendon to cortical bone of the shoulder. A  suture anchor system includes a suture anchor, preferably, a screw anchor, and an installation tool for installing the suture anchor in tissue. The suture anchor defines a longitudinal axis and has a longitudinal cannulation for reception and passage of a guide wire. The suture anchor has trailing and leading ends, and an anchor head adjacent the trailing end thereof. The anchor head includes at least one eyelet for reception of a suture and an internal bore therein. The installation tool includes a main body and a driver head extending from the main body. The main body includes an outer surface having a longitudinal recess therein to accommodate the suture. The driver head is correspondingly dimensioned to be received within the internal bore of the anchor head of the suture anchor whereby movement of the installation tool about a longitudinal axis, e.g., rotational movement, thereof causes corresponding movement, e.g., rotational, of the suture anchor. The installation tool may also define a longitudinal cannulation for reception and passage of the guide wire.
Patent CA-2645807-A1 (CA)
Inventor: LIESKOSKI MAURI
IPC: F24V50/00
Filed: 2007-03-15
Abstract: The invention relates to a system for a low-energy network, comprising a collector circuit (1a, 1b) filled with a first transfer solution, a heat transfer circuit (7) filled with a second transfer solution, and a terminal (3) adapted to transfer heat between the transfer solutions of the collector circuit (1a, 1b) and the heat transfer circuit (7). The system is characterized in that the collector circuits (1a, 1b) are connected to the terminal via two distribution reservoirs (82, 81), of which the first distribution reservoir (81) is isolated and configured to receive and transfer heated transfer liquid, and the second distribution reservoir (82) is configured to receive and transfer cooled transfer liquid, and at least one collector circuit (1a,1b) connecting the first distribution reservoir (81) and the second distribution reservoir (82) is connected to each distribution reservoir (81, 82) terminating the low-energy network. The invention further relates to a distribution tank (80) for a low-energy network.
Patent CA-2646329-A1 (CA)
Title: Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting
Inventor: REITER ROBERT E
IPC: A61K39/395
Filed: 2007-03-20
Abstract: The invention provides novel humanized antibody fragments that specifically bind prostate cell-surface antigen (PSCA), a protein which is overexpressed in variety of cancers, including prostate, bladder, and pancreatic cancer. Methods are provided for the use of the compositions of the invention for the treatment of cancer, diagnosis of cancer, to provide a prognosis of cancer progression, and for cancer imaging.
Patent CA-2648015-A1 (CA)
Title: Generalized interconnection apparatus for delivering services based on real time performance requirements
Inventor: SHAW VENSON
IPC: H04L47/80
Filed: 2007-05-01
Abstract: A system for interconnecting network operators (340a, 340b) with each other based on class of service (360, 365, 370, 380, 390) is provided, taking real-time (360, 365, 370) performance requirements) for each service into consideration, as a result, services can be sent or received in real time, with greater guarantee of network resources, in one non-limiting embodiment, the delivery path for service traffic is based on the real-time performance requirement categories (360, 365, 370) assigned to each service during a pre-processing step. Thus, services having the highest real-time performance (360) demands can be delivered faster using greater network resources, whereas the services without any real-time (380, 390) performance requirements are processed/delivered using fewer network resources.
Patent CA-2649073-A1 (CA)
Title: Compositions and methods for suppression of amyloid plaque formation associated with neurodegenerative disorders
Inventor: MEHLEN PATRICK
IPC: A61K38/18
Filed: 2007-04-16
Abstract: The invention provides a method for reducing or inhibiting net beta-amyloid peptide production and amyloid plaque formation associated with Alzheimer's Disease by administering to a subject an amount of a netrin-1 polypeptide, wherein the netrin-1 polypeptide comprises an amino acid sequence that a) binds to a naturally occurring APP protein and b) inhibits A.beta. peptide production. A netrin-1 polypeptide has an amino acid sequence sufficient for specific binding of the netrin-1 polypeptide to the APP protein. A netrin-1 polypeptide can mimic netrin-1 -mediated signal transduction by altering the localization, protein-protein binding and/or enzymatic activity of an intracellular protein involved in an APP signal pathway. The invention also provides a method for reducing or inhibiting amyloid plaque formation associated with Alzheimer's Disease by administering to a subject an amount of a netrin-1 therapeutic, wherein the netrin-1 therapeutic comprises an amino acid sequence that a) binds to a naturally occurring APP protein and b) inhibits A.beta.peptide production.
Patent CA-2650436-A1 (CA)
Inventor: ZUNIGA JUAN CARLOS
IPC: H04L12/24
Filed: 2007-04-24
Abstract: High throughput channel operation in a mesh wireless local area network (WLAN) is disclosed. A mesh network comprises a plurality of mesh points and a network management entity (NME). The NME is configured to retrieve capability and configuration data from the mesh points. The NME configures at least one mesh point with respect to IEEE 802.11n channelization and legacy protection mode based on the capability and configuration data.
Patent CA-2651319-A1 (CA)
Inventor: SINGH BRIJ P
IPC: C08K3/22
Filed: 2007-05-04
Abstract: A laminate comprising metal oxide and a dye is effective for blocking at least 90% of infrared radiation at a wavelength of 1000 nm while providing transmission of at least 60% of visible light at a wavelength of 555 nm. The laminate includes a transparent substrate such as glass or plastic. The metal oxide can be applied as a coating to the substrate either separate or with the dye. The laminate can be used on generally any type of window such as automobiles, houses, or buildings to prevent transmission of infrared heat therethrough.
Patent CA-2653189-A1 (CA)
Inventor: WRIGHT JAMES S
IPC: C07C39/23
Filed: 2009-02-04
Abstract: The present invention provides new estrogenic compounds of the general formula (see above formula) in which the substituents have the meanings that are explained in more detail in the description, and pharmaceutical compositions containing them. The compounds of the invention are useful, for example, in hormone replacement therapies (HRT/ERT) and as contraceptives and estrogenic hormone therapies. Also provided is a process for synthesizing the compounds of the invention.
Patent CA-2654162-A1 (CA)
Inventor: RADHAKRISHNAN SHAJI E
IPC: H04W4/24
Filed: 2007-06-19
Abstract: Systems and methods for measuring (figure 1) and reporting prepaid service usage are provided (figure2). More particularly, monitoring and reporting packet data session usage for purposes of charging for service usage are provided (figure 3). In some embodiments, layer- 3 data packet monitoring is used to determine usage. In other embodiments, the start and end of a packet data session are used to determine usage. The usage can be determined from the duration of the packet data session or from the size or amount of packets sent and received by a mobile node.
Patent CA-2659781-A1 (CA)
Title: Pos printing triggered by pharmacy prescription orders
Inventor: ROBERTS MICHAEL
IPC: G06Q10/00
Filed: 2008-05-07
Abstract: The invention provides a computer implemented system and method for printing at a POS, comprising: determining in a PM CS of a pharmacy of a retail store a payloadID to association with a prescription order for a prescription ordered from said pharmacy; filling, in said pharmacy, said prescription, to provide a filled prescription; first printing, using a PM CS  printer in said pharmacy, a first print that encodes first information associated with said filled prescription; attaching or physically associating with hardware or adhesive said first print with said filled prescription;  during a purchase transaction in which said prescription is being purchased at a POS terminal of a POS CS of said retail store, reading said first print to determine said first information associated with said filled prescription;  during said purchase transaction, using data lines for retrieving second information associated with said first information; and during said purchase transaction, second printing, using a printer at a POS of said POS  CS, a second print including said second information in human understandable form.
Patent CA-2660476-A1 (CA)
Inventor: FRIEDL THOMAS
IPC: A61K9/20
Filed: 2007-08-10
Abstract: La présente invention concerne des systèmes de libération pharmaceutique comprenant une quantité thérapeutiquement efficace de flibansérine et au moins un excipient pharmaceutiquement acceptable, lesdits systèmes de libération pharmaceutiques étant caractérisés par le fait qu'ils présentent un profil pharmacocinétique caractérisé par une concentration plasmatique moyenne maximale en flibansérine (Cmax) inférieure à 300 ng/ml, de préférence inférieure à 200 ng/ml, après l'administration d'une seule dose à des volontaires sains à jeun ou juste après un repas.
Patent CA-2661798-A1 (CA)
Inventor: JAMES SUSAN P
IPC: G10L21/04
Filed: 2000-10-05
Abstract: An apparatus for compensating for a measured binaural phase time delay profile (BPTD) of an individual comprises means for delaying sound signals to an ear of the individual according to the BPTD, and means for applying different phase shifts at different frequencies according to the BPTD.
Patent CA-2668894-A1 (CA)
Title: Article metering apparatus
Inventor: DUPERRAY PHILIPPE
IPC: B65G47/84
Filed: 2007-11-06
Abstract: A machine for forming a stream of articles (A) into spaced groups of articles, which machine has a working reach and a metering element (10) for being brought into contact with an article (A) passing, in a stream, into the working reach, which metering element (10) is driven by a drive means (18), wherein a speed at which the metering element (10) is driven is retarded as the metering element (10) enters the working reach without retarding the drive means (18).
Patent CA-2669662-A1 (CA)
Title: Cable slitter
Inventor: DELAFOSSE DARYLE
IPC: H02G1/12
Filed: 2009-06-23
Abstract: A cable slitter comprises a support frame and slitting wheel operatively mounted on support frame in position to slit a cable driven longitudinally along the slitting wheel. A rotatable drive wheel is operatively mounted on the support frame for rotation about a substantially horizontal drive axis, in spaced relation from the slitting wheel to together define a substantially longitudinal cable slitting path there between. A slit-adjustment means moves one of the slitting means and the rotatable drive wheel means transversely with respect to the other between a plurality of slitting positions. A drive motor selectively rotates the rotatable drive wheel, to thereby cause a cable in the substantially longitudinal cable slitting path to move forwardly along the substantially longitudinal cable slitting path and engage the slitting wheel, thus causing the cable to be slit.
Patent CA-2671160-A1 (CA)
Title: Procede et appareil de transfert de vapeur mixte et de flux de liquide et procede de refroidissement d'un flux d'hydrocarbure
Inventor: DAM WILLEM
IPC: B01F23/70
Filed: 2007-12-04
Abstract: La présente invention concerne un procédé et un appareil de communication de vapeur mixte et de vapeur liquide entre un premier (101) et un second échangeur thermique (102) ; la vapeur mixe et la vapeur liquide sortent du premier échangeur thermique (101) par le biais de deux orifices ou plus (104). Ensuite, la vapeur mixte et la vapeur liquide présentes dans les orifices (104) passent par deux conduits intermédiaires (103) ou plus vers le second échangeur (102), après quoi la vapeur mixe et la vapeur liquide s'écoulent des conduits intermédiaires (103) dans le second échangeur thermique (102) par le biais de deux ports d'entrée (105) ou plus. Le nombre (X) de ports de sortie (104) est égal ou supérieur au nombre (Y) de ports d'entrée (105).
Patent CA-2672832-A1 (CA)
Inventor: HASHIMOTO SHOJI
IPC: H02P9/04
Filed: 2009-07-23
Abstract: In an inverter generator, having a generator unit driven by an internal combustion engine whose throttle valve is moved by an actuator and generates alternating current, and an inverter that converts converted direct current to alternating current with switching elements to supply to an electrical load, voltage and current supplied to the electrical load is detected, a power factor is calculated from the detected voltage and the current, a power of the load is estimated from the detected current and the calculated power factor. Then a desired speed of the engine is determined based on the estimated power of the load, and the actuator is controlled such that an engine speed becomes equal to the desired engine speed, thereby improving the response of engine speed control.
Patent CA-2676175-A1 (CA)
Title: Pharmaceutical compositions comprising nk1 receptor antagonists and sodium channel blockers
Inventor: ALVARO GIUSEPPE
IPC: A61K31/401
Filed: 2008-01-21
Abstract: The present invention relates to pharmaceutical compositions comprising an NK1 receptor antagonist and a sodium channel blocker compound of formula (I) wherein R1 and R2 are independently hydrogen, C1-6alkyl or C3-6cycloalkyl1-6galkyl; or R1 and R2, together with the nitrogen to which they are attached, may form an unsubstituted 3-, 4-, 5- or 6-membered saturated ring; q is 1 or 2; R3 and R4 are hydrogen; or when q is 1, R3 and R4, together with the interconnecting atoms, may form a cyclopropane ring; X is carbon or nitrogen; n is 0, 1 or 2, wherein when present each R5 is independently selected from the list consisting of C1-3alkyl, halogen, cyano, haloC1-3alkyl, hydroxy, C1-3alkoxy and C1-3haloalkoxy; and either R6 or R7 is -O-R8 or -OCH2R8, wherein the other R6 or R7 is hydrogen or R5; and wherein R8 is either a phenyl ring or a 5- or 6-membered aromatic heterocyclic ring (independently containing one or more nitrogen, sulphur or oxygen atoms) wherein either the phenyl ring or the heterocyclic ring is optionally substituted by one or more groups independently selected from the list consisting of C1-3alkyl, halogen, cyano, haloC1-3alkyl, hydroxy, C1-3alkoxy and C1-3haloalkoxy; or a pharmaceutically acceptable salt or solvate thereof; as a combined preparation for simultaneous or sequential administration, and to the use of such compositions in the treatment of certain disorders, including epilepsy and mood disorders.
Patent CA-2676428-A1 (CA)
Title: Targeted measurements for formation evaluation and reservoir characterization
Inventor: SHENOY RAMACHANDRA G
IPC: G01V1/46
Filed: 2008-06-20
Abstract: A downhole-reconfigurable tool string is utilized to obtain targeted measurements for formation evaluation and reservoir characterization. Tool string hardware and corresponding analysis software are dynamically adjusted to meet specific reservoir description needs identified during or before the logging run with the downhole-reconfigurable tool string. A technique for utilizing the downhole-reconfigurable tool string includes four different steps. The first step includes detecting first order features and identifying second order features. The second step includes enhancing measurements relative to the second order features by reconfiguring tool hardware to extract at least the desired information of the reservoir in terms of its static and dynamic properties, and software focusing to enhance the sensitivity to a particular reservoir attribute. The third step is performing an inversion to reconstruct the reservoir property as accurately as possible. The fourth step is using these properties and the planned production/injection data to recommend suitable monitoring schema.
Patent CA-2676579-A1 (CA)
Title: Platform elevator
Inventor: TREMBLAY PIERRE
IPC: B66F7/02
Filed: 2009-08-14
Abstract: There is provided a platform elevator comprising i) an upright frame having first and second elongated upright members provided with a longitudinal track and an elongated generally orthogonal leg at their lower end, and connected to each other at an upper end thereof by an elongated hoisting box having at least one windable flexible slender hoisting member having a portion extending from a lower end of the box and cooperating with at least one pulley and the frame to constitute a hoisting tackle, and ii) a cantilever platform connected to the tackle and comprising a generally horizontal supporting surface and first and second lateral upright runners adapted to glide in respective tracks of the upright members. Thereby, winding or unwinding the hoisting member causes the platform to be upwardly or downwardly translated by the tackle while being guided by the runners traveling in the tracks.  According to a further aspect of the platform elevator, the hoisting box may further comprise a hoisting member winding means driven by a rotatable shaft connected to a compensating coil spring for partly counterbalancing platform weight and load.
Patent CA-2676638-A1 (CA)
Inventor: LOTH ROBERT
IPC: B27L11/02
Filed: 2008-01-25
Abstract: The invention relates to methods for producing flat chips for oriented strand wood materials. Said method comprises the following steps: a starting product is produced from material containing lignocellulose; the length of said starting product ranges from 20 to 200 mm; the starting product is subjected to a hydrothermal treatment; the treatment lasts at least three minutes and is carried out at a minimum temperature of 40°C; the starting product is cut or chopped.
Patent CA-2676662-A1 (CA)
Inventor: BIER GUNTHER
IPC: G01M3/16
Filed: 2008-01-18
Abstract: The invention relates to a method for determining, and if necessary locating, leaks in pipe (1) by means of at least one electric conductor (L) extending along the longitudinal extension of the pipe (1) from a first measuring point (MSi, i= 1...n) to a second measuring point (MSj, j= 1...n), wherein a measurement signal in the form of temporally variable voltage is applied to the electric conductor (L), and wherein the impedance behavior of the conductor (L) is used to determine the presence of a leak. According to the invention, a first measurement signal in the form of temporally variable voltage is transmitted from the first measuring point (MSi) via the electric conductor (L) to the second measuring point (MSj), and both measuring points (MSi, MSj) evaluate the impedance of the electric line (L), wherein the second measuring point (MSj) by means of a first result signal transmits the result of the impedance evaluation to the first measuring point (MSi) so that it temporally overlaps the first measurement signal, and wherein the first measurement signal and the first result signal are in superposition-free frequency bands.
Patent CA-2677728-A1 (CA)
Title: Thermally crosslinking polyacrylates and method for producing the same
Inventor: BRANDES KAY
IPC: C09J133/00
Filed: 2008-03-18
Abstract: The invention relates to a crosslinker/accelerator system for thermally crosslinking polyacrylates with functional groups that are adapted to react with epoxy groups in a crosslinking reaction. Said system comprises at least one epoxy group-containing substance (crosslinker) and at least one substance (accelerator) that accelerates the crosslinking reaction at a temperature below the melting temperature of the polyacrylate.
Patent CA-2679540-A1 (CA)
Title: Shelf stable sauce for acidified starch
Inventor: HONG YEONG-CHING ALBERT
IPC: A23L23/00
Filed: 2009-09-21
Abstract: A shelf-stable acidified starch and cheese sauce meal is provided. In one aspect, the meal includes an acidified starch component having a pH of about 4.6 or below and a separate cheese-based sauce component having a pH between about 5.7 and about 6.2. The sauce component is to be combined with the acidified starch component when the meal is ready to be consumed. In another aspect, a buffering composition is blended into the separate cheese--based sauce component and includes blends of dibasic phosphate salts, monobasic phosphate salts, and an edible acid where the cheese-based sauce component has a total dry weight of phosphate salt between about 3 and about 5 percent.
Patent CA-2679845-A1 (CA)
Inventor: GROGAN MICHAEL J
IPC: A61P35/00
Filed: 2008-03-07
Abstract: The present invention relates to steroidal alkaloids useful in the treatment of hedgehog pathway related disorders, particularly cancers.
Patent CA-2683077-A1 (CA)
Title: Roll-stabilizing fifth wheel apparatus
Inventor: JARVELIN MICHAEL
IPC: B62D53/08
Filed: 2008-04-30
Abstract: Published without an Abstract
Patent CA-2683629-A1 (CA)
Inventor: VON EUW ERIKA MARIA
IPC: A61K39/00
Filed: 2008-04-11
Abstract: CeIl lines, compositions comprising them for the treatment of melanomas, procedures to prepare the compositions, and treatment methods. More particularly, the invention relates to diverse human melanoma cell lines for the treatment of malignant diseases, wherein the cell lines are: (a) MeI-XYl (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2830), (b) Mel-XY2 (deposited at Germán Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2831), (c) Mel-XY3 (deposited at Germán Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2832), (d) Mel-XX4 (deposited at Germán Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2829), or (e) sub-populations thereof. The cell lines may be irradiated, thus obtaining populations with apoptotic phenotype, and populations with necrotic phenotype of such lines. The compositions may comprise adjuvants and/or immuno-modif iers, and/or autologous dendritic cells.
Patent CA-2687119-A1 (CA)
Inventor: MUNDT WOLFGANG
IPC: C12Q1/70
Filed: 2008-04-30
Abstract: The present invention provides a method for purification of a virus or virus antigen comprising providing a virus preparation and centrifugation of said virus preparation in a gradient of a sugar established by the addition of two or more buffered sugar layers of different concentration. The method leads to higher yields and reduces unwanted aggregation of the virus or virus antigen by increasing the volume of the peak pool.
Patent CA-2688079-A1 (CA)
Inventor: BIANCHI GIUSEPPE
IPC: A61P17/02
Filed: 2008-06-04
Abstract: Compound of formula (I), wherein the symbol have the meaning reported in the text; for preparing a medicament for the prevention and/ or treatment of obstructive vascular lesions following vascular surgery and for the prevention and/or treatment of diseases due to organ fibrosis.