baber/WOPTO huggingface dataset:
Patent RU-2287160-C2 (RU)
Title: Количественный диагностический анализ гипертензии
Inventor: LANG FLORIAN
IPC: C12Q1/6883
Filed: 2002-03-21
Granted: 2006-11-10
Abstract: Изобретение относится к области медицины и касается способа диагностики in vitro, обусловленной генетическими факторами предрасположенности к гипертонии посредством выявления в образце (а) SNP, который выявляют в экзоне 8(С→Т) гена hsgk1 и представленном в SEQ ID NO:1, а также (б) SNP, который выявляют в интроне 6(Т→С) гена hsgk1 и локализованном во фрагменте размером 551 п.о. против хода транскрипции по отношению к SNP в экзоне 8 согласно подпункту (а), или обоих SNP согласно подпунктам (а) и (б). Изобретение также относится к применению таких SNP для получения диагностикумов и наборов для диагностики обусловленной генетическими факторами предрасположенности к гипертонии. Преимущество изобретения заключается в обнаружении конкретных последовательностей гена hsgk1, обуславливающих предрасположенность к гипертонии. 3 н.п. ф-лы, 5 табл., 1 ил.
Patent RU-2336260-C2 (RU)
Inventor: DALLORO LEONARDO
IPC: C07C37/88
Filed: 2003-10-14
Granted: 2008-10-20
Abstract: FIELD: chemistry. 
     SUBSTANCE: flow of water solution of dioxybenzole with concentration from 5 to 60 wt % with volume rate, expressed in kg of dioxybenzole/hour/kg of catalyst 0.1 - 10 hours -1 , and hydrogen flow are supplied to adiabatic reactor with immobile layer of catalyst. Reaction of hydrodeoxygenation in vapour phase working in continuous regime in presence of catalyst is performed. Flow of dioxybenzole water solution and hydrogen flow are supplied in such amount that ratio between total quantity of hydrogen and dioxubenzole moles was within range from 2:1 to 50:1. Reaction is carried out at temperature within range from 250 to 500°C and pressure 0.1-10 MPa. Used catalyst represents catalyst on carrier, containing element of group VIB, or their mixture, or element of group VIII of periodic system, or their mixture and promoter. 
     EFFECT: invention allows to increase decree of dioxybenzole conversion, selectivity in relation to phenol and process productivity. 
     21 cl, 27 ex, 1 dwg
Patent RU-2265854-C2 (RU)
Inventor: GLAZOVA T G
IPC: G01N33/86
Filed: 2003-10-14
Granted: 2005-12-10
Abstract: FIELD: medicine, pulmonology. 
     SUBSTANCE: along with analyzing pulmonary symptoms and functions, one should additionally evaluate procoagulant activity of plasmatic blood phospholipid membranes by the value of kaolin terms for clotting. At its value being 108.5±2.9 sec it is easy to state upon light intermittent bronchial asthma (BA), at 99.4±1.3 sec - on light persisting BA, at 116.5±3.1 sec - on average BA, at 123.8±4.6 sec - on severe BA. The present innovation is useful in prescribing corresponding curative-rehabilitation procedures. 
     EFFECT: higher accuracy of diagnostics. 
     4 ex, 1 tbl
Patent RU-2302883-C2 (RU)
Inventor: KHAAPAKUMPI TIMO
IPC: A61K31/56
Filed: 2002-08-27
Granted: 2007-07-20
Abstract: FIELD: medical engineering. 
     SUBSTANCE: system is selectable from a group having implant, intrauterine system, intracervical system or intravaginal system having core and membrane. The core has at least one therapeutic agent and at least the first and the second part. At least one separating membrane is available between the first and the second part. The core and membrane are manufactured from elastomer composition like poly(dimethylsiloxane), siloxane -based elastomer having 3,3,3-trifluoropropyl groups attached to Si atoms of siloxane links, or elastomer composition having poly(alkyleneoxide) groups available as alcoxi- terminal engrafting or units connected to polysiloxane links with carbonic silicon bonds, or as mixture of given forms and combination at least of two from them. The core and membrane have identical or different elastomer compositions. 
     EFFECT: enabled at least two agents release at the same time at preset rates; excluded harmful action in system damage cases. 
     22 cl, 14 dwg
Patent RU-2270180-C2 (RU)
Inventor: RUSIN MIKHAIL JUR EVICH
IPC: C04B35/14
Filed: 2004-04-01
Granted: 2006-02-20
Abstract: FIELD: aircraft industry, structural materials. 
     SUBSTANCE: claimed material contains (mass %) sintered silicium dioxide of 7-12 % porosity 98.0-99.0 and organosiloxane resin (e.g., methylphenylspirosiloxane) 1.0-2.0. Method of invention includes impregnation of sintered silicium dioxide with organosiloxane resin followed by drying in air for 3-24 h and polymerization at 200-230°C for 3-4 h. Material of present invention has resistance increased by 30-50 % as compared with starting material and is useful in production of antenna dome working at 950°C without losses of characteristics. 
     EFFECT: composite material for aircraft industry of improved characteristics. 
     2 cl, 4 ex, 1 tbl
Patent RU-2294331-C2 (RU)
Inventor: KHANSSEN ROBERT GERARD JULES M
IPC: A61K31/519
Filed: 2002-08-29
Granted: 2007-02-27
Abstract: FIELD: organic chemistry, medicine, pharmacy. 
     SUBSTANCE: invention describes glycine-substituted thieno[2,3-D]-pyrimidines of the formula (I):   wherein X represents oxygen atom (O) or H,H; A represents sulfur atom (S), -NH, -N(R 6 ), O or a bond; R1 represents (C 1 -C 4 )-alkyl, (C 2 -C 4 )-alkenyl, unsubstituted or substituted phenyl, thienyl, pyridyl; R2 represents hydrogen atom (H), (C 1 -C 4 )-alkyl, (C 1 -C 4 )-alkoxy-(C 2 -C 4 )-alkyl or hydroxy-(C 2 -C 4 )-alkyl; R3 and R4 are chosen independently from H, (C 1 -C 4 )-alkyl and hydroxy-(C 1 -C 4 )-alkyl; R5 represents H or (C 1 -C 4 )-alkyl, and R 6  represents (C 1 -C 4 )-alkyl. Compound possess agonistic activity with respect to glycoprotein hormone, in particular, to compounds possessing agonist activity with respect to luteinizing  hormone (LH) and follicle-stimulating hormone (FSH). Also, invention describes pharmaceutical compositions containing such compounds and using these compounds in medicinal therapy, in particular, for fertilization control. 
     EFFECT: valuable biological and medicinal properties of compounds. 
     11 cl, 1 tbl, 27 ex
Patent RU-2274548-C2 (RU)
Inventor: KLINKOV ALEKSEJ STEPANOVICH
IPC: B29B7/40
Filed: 2004-06-07
Granted: 2006-04-20
Abstract: FIELD: preparation or pretreatment of materials to be shaped. 
     SUBSTANCE: mixing head comprises housing and mixing sleeve.  The sleeve receives the sectional rotor.  Each section of the rotor is made of an ellipse whose greater axis relates to the smaller one as 1.5-2.  The grater axes of the sections are inclined at an angle of 0-90°.  The central opening in the sections and working section of the driving shaft are ribbed. 
     EFFECT: enhanced efficiency of mixing and expanded functional capabilities. 
     2 dwg
Patent RU-2305095-C2 (RU)
Inventor: KONG NORMAN
IPC: C07D405/04
Filed: 2002-12-09
Granted: 2007-08-27
Abstract: FIELD: organic chemistry, medicine, pharmacy. 
     SUBSTANCE: invention relates to novel compounds of the formula (I):   wherein R means -C(O)R 1  wherein R 1  is chosen from the series: (C 1 -C 6 )-alkyl, -C=CH-COOH, -NHCH 2 -CH 2 R 2 , -N(CH 2 -CH 2 OH)CH 2 -CH 2 OH, -N(CH 3 )CH 2 -CH 2 -NHCH 3 , -N(CH 3 )CH 2 -CH 2 N(CH 3 )CH 3 , saturated 4-, 5- and 6-membered cycles and saturated and unsaturated 5- and 5-membered cycles comprising at least one heteroatom from a series sulfur (S), nitrogen (N) and oxygen (O), and optionally substituted with a group chosen from the series: (C 1 -C 6 )-alkyl, -C=O-R 5 , -OH, (C 1 -C 6 )-alkyl substituted with hydroxy-group optionally, (C 1 -C 6 )-alkyl substituted optionally with a group of the series: -NH 2 , -N-(C 1 -C 6 )-alkyl, -SO 2 CH 3 , =O, and 5- and 6-membered saturated cycles comprising at least one heteroatom chosen from N and O, and wherein R 5  is chosen from the series: hydrogen atom (H), (C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkyl substituted with hydroxy-group optionally, and (C 1 -C 6 )-alkyl substituted with NH 2 -group optionally; R 2  is chosen from the series: -N(CH 3 )CH 3 , -NH 2 , morpholinyl and piperazinyl; X 1 , X 2  and X 3  are chosen independently from the series: -OH, (C 1 -C 2 )-alkyl, (C 1 -C 6 )-alkoxy-group, -Cl, -Br, -F, -CH 2 OCH 3  and -CH 2 OCH 2 CH 3 , or one among X 1 , X 2  or X 3  means hydrogen atom, and two others are chosen independently from the series: hydroxy-group, (C 1 -C 6 )-alkyl, (C 1 -C 6 )-alkoxy-group, -Cl, -Br, -F, -CF 3 , -CH 2 OCH 3 , -CH 2 OCH 2 CH 3 , -OCH 2 -CH 2 R 3 , -OCH 2 -CF 3  and -OR 4 , morpholylmethyl, -N(CH 3 )CH 3 , -CH 2 OH, -COOH, or one among X 1 , X 2  or X 3  means hydrogen atom, and two others in common with two carbon atoms including bonds between them in benzene cycle to which they are bound optionally form 5- or 6-membered saturated cycle comprising at least one heteroatom chosen from S, N and O, and wherein R 3  is chosen from the series: -F, -OCH 3 , -N(CH 3 )CH 3 , saturated 5-membered cycle comprising at least one heteroatom N; R 4  means 3-5-membered saturated cycle, and each Y 1  and Y 2  is chosen independently from the series: -Cl, -Br, -NO 2 ,-C≡N and C≡N, and compound of the formula (II) also given in the invention description. Also, invention relates to a pharmaceutical composition possessing anti-proliferative activity and based on these compounds. Invention provides preparing novel compounds possessing the useful biological properties. 
     EFFECT: valuable medicinal properties of compounds and pharmaceutical composition. 
     28 cl, 39 ex
Patent RU-2325161-C2 (RU)
Title: Use of ranolazine for preparation of medicine for arrhythmia treatment
Inventor: BELARDINELLI LUIZ
IPC: A61P9/06
Filed: 2003-04-04
Granted: 2008-05-27
Abstract: FIELD: medicine. 
     SUBSTANCE: invention is related to the use of ranolazine and its analogues for preparation of medicine for treatment of acquired or congenital arrhythmias with elongated QT. The invention ensures efficient treatment with minimum side effects due to the ability of these compounds in therapeutic doses to inhibit I Kr , I Ks  and later I Na  -ion channels without inhibition of calcium channels. 
     EFFECT: efficient treatment. 
     36 cl, 25 dwg, 19 tbl, 50 dwg
Patent RU-2285149-C2 (RU)
Inventor: GUSAK STANISLAV IVANOVICH
IPC: F03D3/04
Filed: 2004-11-16
Granted: 2006-10-10
Abstract: FIELD: wind-power engineering; vortex wind-power plants equipped with converging passages. 
     SUBSTANCE: proposed wind-power plant has windwheel mounted in tube at the top and provided with vertical axle; windwheel is kinematically linked with energy converter in form of electric generator; converging passages are arranged in tiers; they are arranged in each tier spirally around vertical axle and helically along it. Narrowed sections of passages form vortex flow zone. 
     EFFECT: enhanced efficiency; enhanced steadiness of vortex flow with no break-away due to dense and laminar flow. 
     16 cl, 5 dwg
Patent RU-2291595-C2 (RU)
Title: Method for heating flat surface of object by flat electric heater adjacent to it from one side
Inventor: BOCHKAREV VASILIJ KUZ MICH
IPC: H05B3/20
Filed: 2004-11-26
Granted: 2007-01-10
Abstract: FIELD: technologies for heating products for home and technical use. 
     SUBSTANCE: in accordance to method contact between surface of object and heater surface is realized along periphery of this surface of heater, while thermal radiation of opposite flat surface of heater is focused in its middle onto flat surface of object. 
     EFFECT: increased efficiency of heating, increased efficiency of electric engine and decreased flow of electric energy. 
     6 dwg
Patent RU-2285101-C2 (RU)
Title: Устройство с элементами скольжения
Inventor: LJATOVETS VLADIMIR VIKTOROVICH
IPC: E06B9/02
Filed: 2004-12-07
Granted: 2006-10-10
Abstract: Изобретение относится к области строительства и может быть использовано для изготовления раздвижных стенок ограждающих конструкций или для остекления балконов. Изобретение позволит упростить конструкцию устройства с элементами скольжения и повысить надежность ее работы. Устройство с элементами скольжения для раздвижных стенок ограждающих конструкций или для остекления балконов содержит расположенные в одной плоскости неподвижные элементы и расположенные в другой плоскости подвижные элементы, выполненные с возможностью скольжения и имеющие тела качения, расположенные в нижней их части, верхнюю направляющую, нижнюю направляющую с беговой дорожкой, повторяющей форму беговой дорожки тела качения и уплотняющие элементы. Верхняя направляющая выполнена с разновеликими по ширине пазами. Наружный паз выполнен с шириной, меньшей ширины внутреннего паза. Наружная сторона верхней направляющей имеет отогнутую внутрь полку, расстояние от конца которой до средней части верхней направляющей меньше толщины верхней части неподвижного элемента. Внутренний паз имеет большую ширину, чем толщина верхней части подвижного элемента скольжения. Нижняя направляющая имеет две части, первая из которых выполнена с горизонтальной полкой для опоры неподвижного элемента, закрепленного к вертикальной стенке, примыкающей к горизонтальной полке. Вторая часть нижней направляющей выполнена с беговой дорожкой и расположена на связанной с вертикальной стенкой горизонтальной полке, находящейся выше горизонтальной полки первой части нижней направляющей. 3 з.п. ф-лы, 4 ил.
Patent RU-2286505-C2 (RU)
Title: Device for protecting couplings of communications
Inventor: PETROV RUDOL F ALEKSEEVICH
IPC: F16L37/28
Filed: 2005-01-11
Granted: 2006-10-27
Abstract: FIELD: couplings of the quick-acting type. 
     SUBSTANCE: device comprises movable casing and coupling provided with pins and clamps.  The coupling is pivotally mounted on the carriage that is set in motion by means of an air-operated cylinder.  The movable casing is made for permitting longitudinal and transverse movements inside the protecting structure, and the carriage is mounted separately from the casing.  The casing is kinematically connected with the carriage through the rollers and is mounted on the rollers in the guides of the protecting structure.  The casing is also connected with the rollers through the springs and is provided with actuator and pressing mechanism.  The pressing mechanism has double-arm levers pivotally connected with the control air-operated cylinders provided with springs and drain valves.  The double-arm levers are mounted in the axles of the cantilevers of the protecting structure and kinematically connected with the stop of the cantilevers and movable casing. 
     EFFECT: enhanced reliability. 
     6 dwg
Patent RU-2293809-C2 (RU)
Inventor: KAMALUTDINOV MASKHUT KUTDUSOVI
IPC: D07B7/02
Filed: 2005-01-11
Granted: 2007-02-20
Abstract: FIELD: equipment for manufacturing of untwisting coiled articles, in particular, technique for preliminary deformation of members to be coiled for manufacture of coiled articles. 
     SUBSTANCE: apparatus has distributing disk rigidly connected to casing, rear, intermediate and front disks successively arranged for axial movement on casing and equipped with deforming units. Deforming units are made in the form of trapezium-shaped quenched plates having thickness of from 5 mm to 10 mm, length of from 10 mm to 30 mm and distance between plates of from 1 mm to 5 mm. Side surfaces of trapezium-shaped plates are provided with rounded portions having radius equal to half the thickness of plate. 
     EFFECT: increased efficiency of apparatus and improved quality of coiled articles. 
     4 cl, 4 dwg
Patent RU-2340619-C2 (RU)
Inventor: DZHASTI VENKATESVARLU
IPC: A61P25/16
Filed: 2003-06-19
Granted: 2008-12-10
Abstract: FIELD: chemistry. 
     SUBSTANCE: in general formula (I)  , R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11  and R 12  can be similar or different and represent, each independently, hydrogen, halogen, hydroxyl, unsubstituted (C 1 -C 6 )alkyl, (C 1 -C 6 )alkoxy, or neighbouring groups R 2  and R 3  together with carbon atoms to which they are bound, can form benzol ring; R 13  and R 14  can be similar or different and represent each independently, hydrogen, unsubstituted (C 1 -C 6 )alkyl, optionally, R 13  and R 14  together with nitrogen atom can form 5-, 6-member heterocyclic ring, where heterocycle also can be substituted (C 1 -C 6 )alkyl, and it can have "additional heteroatoms", selected from O, N; "n" is an integer in interval from 1 to 4, and carbon chain, to which it relates is linear. 
     EFFECT: compound possess the characteristic of activity modulators 5-HT and can be applied for treatment of such diseases as anxiety, depression, convulsive syndromes, migraine. 
     15 cl, 67 ex
Patent RU-2298752-C2 (RU)
Inventor: GORSHKOV ALEKSANDR SERGEEVICH
IPC: F28D15/02
Filed: 2005-01-27
Granted: 2007-05-10
Abstract: FIELD: heat-exchange processes, applicable in chemical engineering, power engineering, cryogenic engineering. 
     SUBSTANCE: the method consists in the fact that circulation of the heat-transfer agent is accomplished in a closed circuit through a heat-exchange element located in the reactor, circulation of the high-boiling heat-transfer agent is accomplished in a closed circuit, and the heat-exchange element is made in the form of an air lift circulation unit, the low-boiling liquid is fed to the heat-exchange element, boiling of the low-boiling liquid is organized with formation of bubbles of the low-boiling liquid, and thus an ascending current of the heat-transfer agent in the heat-exchange element is formed, after that the ascending current of the heat-transfer agent is directed to a remote heat exchanger, in the latter the current of the heat-transfer agent is cooled, a descending current of the mixture of the low-boiling liquid and the high-boiling heat-transfer agent is formed in the process of cooling, the mixture is condensed in the process of cooling, after that it is separated, the high-boiling heat-transfer agent is returned to the heat-exchange element, and the low-boiling liquid is directed to the heat-exchange element for production of an ascending current of the heat-transfer agent. 
     EFFECT: provided intensification of the heat exchange from liquid heat-transfer agent, enhanced hydrodynamic stability of the heat exchange condition, reduced power consumption. 
     1 tbl
Patent RU-2326917-C2 (RU)
Inventor: GERREH OLIV E
IPC: A61F13/00
Filed: 2003-07-21
Granted: 2008-06-20
Abstract: FIELD: chemistry. 
     SUBSTANCE: invention relates to the binding agent for the adhesive composition which is a block-copolymer derived by means of controlled radical polymerisation that has specific composition, structure and is used to ensure adhesion in moist environment and contains at least one hydrophylic block and can be added into the adhesive composition meant for using in moist environment. The binding agent can be used in the adhesive compositions for a number of medical applications (protective, prosthetic devices) as well as for paramedical applications (protective, bandages) which should not unglue even under the influence of water. The binding agent for the adhesive composition insuring adhesion in moist environment is a block copolymer which has at least one hard hydrophylic block (B) that is non-operating phase, dispersed as nanodomain and at least one hydrophobus block (A) of elastomeric nature that is the main phase characterised with water absorbing capacity w ∞ (A), less 20%. 
     EFFECT: binding agent of the adhesive compositions for usage in dry and moist environment was prepared. 
     18 cl, 1 tbl, 11 ex
Patent RU-2296662-C2 (RU)
Title: New laser machine tool for cutting facets
Inventor: PATEL ARVINDBKHAJ LAVDZHIBKHAJ
IPC: B28D1/22
Filed: 2003-07-18
Granted: 2007-04-10
Abstract: FIELD: diamond working, possibly manufacture of machine tools for cutting facets of diamonds. 
     SUBSTANCE: machine tool is designed for cutting facets of diamonds by means of laser beam and it includes holder of diamond, mounting attachment and cutting attachment. Diamond holder includes abutting and magnetic mandrels. Mounting attachment includes interface of central navigation computing device and video system and it provides performing operation for centering diamond. After ending such operation diamond holder with diamond is transmitted to cutting attachment. The last includes interface of central navigation computing device, heat exchanger, video system, mechanism for directing beam, laser irradiation source, power supply source and stabilizer. Mechanism for directing beam allows perform processes for diamond facet cutting and polishing diamond with rounding. 
     EFFECT: improved efficiency of cutting diamond, lowered losses of diamond mass, possibility for receiving strictly round diamonds of different sizes with use of standard software of computer. 
     23 cl, 16 dwg, 4 ex
Patent RU-2335497-C2 (RU)
Inventor: NEU JOZHEF
IPC: C07D253/075
Filed: 2003-09-18
Granted: 2008-10-10
Abstract: FIELD: chemistry. 
     SUBSTANCE: invention claims a new method of obtaining 3,5-diamino-6-(2,3-dichlorphenyl)-1,2,4-triazine of high purity degree by reaction of 2,3-dichlorbenzoylcyanide with 1-2 mol equivalents of dimethylase aminoguanidine salt in the presence of 3-6 mol equivalents of methanesulfoacid, with further addition of 2-5 mol equivalents of magnesium oxide to the reaction mix. The process is performed at 50-80°C, and target product is recrystallised from acetone. 
     EFFECT: improved efficiency of compounds. 
     5 cl, 3 ex
Patent RU-2294713-C2 (RU)
Inventor: EMANOV ANDREJ ALEKSANDROVICH
IPC: A61D1/00
Filed: 2005-04-25
Granted: 2007-03-10
Abstract: FIELD: veterinary; surgical instruments for veterinary. 
     SUBSTANCE: attachment can be used for curing damages in animals' bone. It intends for use as additional aid for performing intra-bone osteosynthesis of shoulder and ankle bones. By means of attachment the apparatus' module is fixed stable at required position during operation. It can be also used in experimental medicine for modeling breaks. Attachment has support made in form of frame. Two sides of frame are made in form of telescopes, and two other sides are made in form of T-shaped planes. Screw-shaped plank is attached to any vertical surface of T-shaped planes for movement. Screw-shaped plank is connected by hinge with other screw-shaped plank. Any screw-shaped plank is provided with openings. Rib of hardness is fixed inside frame. Posts are fastened to any end of telescopes; posts are provided with rubber areas at the ends. Doctor's hands keep free during manipulations; he/she is able of adjusting height and length of structure depending on size of animal or driving supports of apparatus in motion during manipulation and of doing traction of bone fractures in apparatus. 
     EFFECT: improved efficiency of operation. 
     2 cl, 4 dwg
Patent RU-2298862-C2 (RU)
Inventor: BELJAEV VIKTOR VJACHESLAVOVICH
IPC: H01P1/16
Filed: 2005-07-13
Granted: 2007-05-10
Abstract: FIELD: microwave engineering including satellite television engineering. 
     SUBSTANCE: proposed waveguide polarizer has waveguide section in the form of truncated pyramid and two wedges used to organize square-section-to-T adapter. Wedge base equals 0.2λ x 0.7 λ and its height equals that of waveguide section, where λ is wavelength in free space. Newly introduced are two groups of adjusting members, each group incorporates three members and is disposed along axial lines of waveguide wide walls forming T-section. First member is spaced through distance of λ av /4 from T-section and next ones, λ mean /8 from each other, where λ mean  is mean wavelength in waveguide. Waveguide ellipticity = 0.98, standing-wave ratio = 0.95, bandpass = 18%. 
     EFFECT: improved characteristics, simplified design. 
     1 cl, 3 dwg