baber/WOPTO huggingface dataset:
Patent WO-2019161297-A1 (WO)
Title: Apparatus and methods for selectively transmitting objects
Inventor: NEISER PAUL
IPC: G02B9/00
Filed: 2019-02-15
Abstract: Apparatus and methods for selectively transmitting objects of interest from a first reservoir to a second reservoir are disclosed. The apparatus includes electromagnetic focusing apparatus configured to interact with objects of interest to induce a change in a property of the objects of interest so as to increase the probability that the objects of interest through a throat diffusively coupling the first reservoir and the second reservoir.
Patent WO-2019165071-A1 (WO)
Title: Edible oil refining
Inventor: TARNOW ARMIN
IPC: C11B3/14
Filed: 2019-02-21
Abstract: The present invention relates to a process for improving the quality of edible oils or fats and in the process an edible oil is passed through an oil refining equipment consisting of a stripping column with packing and not more than one oil collection tray. It further relates to the use of the refining equipment consisting of a stripping column with packing and not more than one oil collection tray, for degrading, decomposing or breaking down oxidation products of triglycerides, diglycerides, monoglycerides and/or fatty acids.
Patent WO-2019165454-A1 (WO)
Title: Modified plyss2 lysins and uses thereof
Inventor: SCHUCH RAYMOND
IPC: C12N9/14
Filed: 2019-02-26
Abstract: Disclosed herein are modified lysin polypeptides thereof comprising at least one amino acid substitution as compared to a wild-type PlySs2 lysin polypeptide having an amino acid sequence of SEQ ID NO: 1, wherein the at least one amino acid substitution is in the CHAP domain and/or the SH3b domain, and wherein the modified lysin polypeptide or fragment thereof inhibits the growth, reduces the population, or kills at least one species of Gram-positive bacteria. Further disclosed herein are compositions comprising the modified lysin polypeptides, as well as vectors comprising a nucleic acid molecule that encodes the modified lysin polypeptide. Also disclosed herein are methods of inhibiting the growth, reducing the population, or killing at least one species of Gram-positive bacteria, methods of treating a bacterial infection, and methods of augmenting the efficacy of an antibiotic or reducing the development of antibiotic resistance.
Patent WO-2019183375-A1 (WO)
Inventor: NAKANO YOKO
IPC: C07K16/28
Filed: 2019-03-21
Abstract: The present application provides antibody agents specifically recognizing monocarboxylate transporter 4 (MCT4), such as a cell surface-bound MCT4. Also provided are methods of making and using these antibody agents.
Patent WO-2019183482-A1 (WO)
Inventor: SHAY JERRY
IPC: A61P35/04
Filed: 2019-03-22
Abstract: Brain tumors remain the leading cause of cancer-related deaths in children and often are associated with long-term sequelae among survivors of current therapies. Telomerase and telomeres play important roles in cancer, representing attractive therapeutic targets to treat children with poor-prognosis brain tumors such as diffuse intrinsic pontine glioma (DIPG), high-grade glioma (HGG) and high-risk medulloblastoma (MB). It has shown that DIPG, HGG and MB frequently express telomerase activity. It is now shown that the telomerase-dependent incorporation of 6-thio-2'deoxyguanosine (6-thio-dG), a telomerase substrate precursor analog, into telomeres leads to telomere dysfunction-induced foci (TIFs) along with extensive genomic DNA damage, cell growth inhibition and cell death of primary stem-like cells derived from patients with DIPG, HGG and MB. Importantly, the effect of 6-thio-dG is persistent even after drug withdrawal. Treatment with 6-thio-dG elicits a sequential activation of ATR and ATM pathways and induces G 2 /M arrest.  In vivo , treatment of mice bearing MB xenografts with 6- thio-dG delays tumor growth, increases in-tumor TIFs and apoptosis. Furthermore, 6-thio-dG crosses the blood-brain barrier and specifically targets tumor cells in an orthotopic mouse model of DIPG. Together, these findings suggest that 6-thio-dG is a promising approach to treat therapy -resistant telomerase-positive pediatric brain tumors.
Patent WO-2019191585-A1 (WO)
Title: Systèmes et procédés de fabrication additive
Inventor: FELDMANN MARTIN C
IPC: B29C35/02
Filed: 2019-03-29
Abstract: Des aspects de l'invention concernent des systèmes de fabrication additive et des procédés associés. Un système de fabrication additive peut comprendre deux sources d'énergie laser ou plus et des fibres optiques associées. Un ensemble optique peut être construit et agencé pour former un pixel d'énergie laser rectangulaire associé à chaque source d'énergie laser. Chaque pixel peut avoir une densité de puissance sensiblement uniforme et les pixels peuvent être agencés pour former un réseau linéaire de pixels d'énergie laser sur une surface de construction sans espacement entre les pixels. L'exposition d'une partie d'une couche de matériau sur la surface de construction au réseau linéaire de pixels d'énergie laser peut faire fondre la partie de la couche.
Patent WO-2019212762-A1 (WO)
Title: System comprising a protective cover and a preform of a body part fixation device
Inventor: COPPLE CRAIG
IPC: B29C51/42
Filed: 2019-04-19
Abstract: An assembly for a thermoplastic preform for securing body part is provided. The thermoplastic preform is deformable when heated to a softening temperature by an external heating source and hardens when cooled below the softening temperature. The assembly includes the thermoplastic preform and a protective cover surrounding the thermoplastic preform. The thermoplastic preform is sealed within the protective cover. The protective cover is heat resistant up to a temperature that exceeds the softening temperature for the thermoplastic preform. The protective cover transfers heat from the external heating source to the thermoplastic preform and prevents airborne and waterborne bacteria from contacting the thermoplastic preform.
Patent WO-2020096645-A1 (WO)
Title: Polyethylene compositions and articles made therefrom
Inventor: LI DONGMING
IPC: C08F10/02
Filed: 2019-05-13
Abstract: This invention relates to a polyethylene composition, and films therefrom, comprising at least 65 wt% ethylene derived units and from 0.1 to 35 wt% of C3-C12 olefin comonomer derived units, where the polyethylene composition has: a) an RCI,m of less than 85 kg/mol; b) a Twi- Tw2 value of from -15 to -40°C; and c) an MWI/MW2 value of less than 1.5 where the film has a) a heat seal initiation temperature of X°C or less at 5 N of force, where X=0.00l5xY(psi) + 62.6 (where Y is the average 1% Secant modulus ((MD+TD)/2)) of the film; b) a dart drop impact of 300 g/mil or more; c) an MD Elmendorf tear of 230 g or more; and d) average 1% Secant modulus ((MD+TD)/2) of 20,000 psi or more.
Patent WO-2019231688-A1 (WO)
Title: Cloud storage distributed file system
Inventor: MAINALI SHANE KUMAR
IPC: G06F16/182
Filed: 2019-05-16
Abstract: Methods, systems, and computer programs are presented for providing file system functions on a cloud storage system based on blob storage. A cloud storage system comprises storage clusters, and each storage cluster comprises a plurality of storage nodes (each including a partition layer that stores data in blobs organized within containers, and a stream layer for streaming blob data), a hierarchical namespace service for implementing file system functions on the data stored in the blobs and, a front end layer for processing user requests to access and manage data stored on the blobs. The file system functions include flat namespace functions and hierarchical namespace functions. Further, the front end layer accesses the partition layer to access the blobs based on addresses of blobs and accesses the hierarchical namespace service to identify the blobs.
Patent WO-2019226755-A1 (WO)
Inventor: MARCUCCIO SEBASTIAN MARIO
IPC: A61P15/00
Filed: 2019-05-22
Abstract: La présente invention concerne des sels d'acides aminés de ribosides d'acide nicotinique et des compositions de ceux-ci de formule I, utiles dans le traitement de troubles et de maladies associés à des déficiences en NAD +:. Dans ladite formule, M1, R1, R2 et R3 sont tels que décrits dans la description.
Patent WO-2019232021-A1 (WO)
Title: Conductive Outer Jacket for Wireline Cable
Inventor: VARKEY JOSEPH
IPC: E21B47/01
Filed: 2019-05-29
Abstract: A cable containing a conductive outer layer and methods for manufacturing the conductive outer layer and the cable are provided. A cable may include a cable core and a plurality of armor wire strength members that surround the cable core. The cable may also include a conductive outer layer disposed about the plurality of armor wire strength members that physically contacts at least one armor wire strength member of the plurality of armor wire strength members.
Patent WO-2020023418-A1 (WO)
Inventor: NAVIA MANUEL
IPC: A61K35/28
Filed: 2019-07-22
Abstract: L'invention concerne une méthode de traitement d'un sujet ayant un trouble neurologique caractérisé par la présence de protéines de répétition dipeptidiques comprenant la mise en contact du liquide céphalorachidien (CSF) du sujet avec un agent capable d'éliminer ou de dégrader la protéine toxique.
Patent WO-2020036827-A1 (WO)
Title: Advanced preferred path route graph features in a network
Inventor: ECKERT TOERLESS
IPC: H04L45/52
Filed: 2019-08-09
Abstract: A method implemented by a network element (NE) in a network, comprising receiving, by the NE, preferred path route (PPR) information comprising a PPR identifier (PPR-ID) and a plurality of PPR-Path Description Elements (PPR-PDEs), wherein a PPR-PDE describing the egress NE comprises a destination flag, an anycast PPR-ID, and an anycast group PPR-ID associated with the egress NE, and updating, by the NE, a forwarding database to include a forwarding entry for the egress NE, wherein the forwarding entry includes the PPR-ID, the anycast PPR-ID, and the anycast group PPR-ID, and wherein the forwarding entry indicates a next element on the PPR graph by which to forward an anycast data packet comprising the anycast PPR-ID.
Patent WO-2020055707-A1 (WO)
Title: Surgical robotic systems and methods of tracking usage of surgical instruments thereof
Inventor: RAMADORAI ARVIND
IPC: A61B90/00
Filed: 2019-09-09
Abstract: A method of tracking usage of a robotic surgical instrument includes capturing an image of a surgical instrument with an imager during a robotic surgical procedure, identifying a type of the surgical instrument based on the image of the surgical instrument, determining a degree of usage of the surgical instrument based on data acquired by at least one sensor, and determining a stage in a life cycle of the surgical instrument based on the type of surgical instrument identified and the degree of usage determined.
Patent WO-2020061188-A1 (WO)
Inventor: JESSUP CHRIS
IPC: B60R22/48
Filed: 2019-09-18
Abstract: A buckle has a buckle mechanism with a lock pawl and a latch pin. The latch pin is designed to travel only in a longitudinal or horizontal direction relative to the buckle mechanism. When a latch plate assembly is secured, the latch pin holds the lock pawl in a latched position and prevents accidental release of the latch plate assembly. A release button is coupled to the latch plate retention bar so that all of the effective actuation and other motions are in the longitudinal direction of the buckle mechanism. The buckle mechanism has an ejector mechanism with an ejection spring for ejecting the latch plate assembly.
Patent WO-2020106381-A1 (WO)
Inventor: LERNER DANIEL MAURICE
IPC: F04B49/24
Filed: 2019-10-15
Abstract: Multiport pumps and associated pumping systems described provide a selective hydraulic or electrically powered pump/pump system. The pumps provide movement within a device or larger system. Movement can cause compression/expansion of fluid and provide fluid movement within the same device or system. In this instance, the volume of fluid and the fluid flow path within, from, and to the pump(s) is kept constant to reduce or eliminate cavitation, seizure, and/or hydraulic lock. Use of at least one reservoir comprising; a compensator tank, a port allowing for operation at ambient pressure, and a pressure measuring device measuring pressure allowing for unbalanced flow to and from the multiport pumps along with thermal expansion or compression is detailed. In addition, use of a multiport swashplate pumps and associated valve plates that incorporate the features and functions of several valves not heretofore provided within the pump itself is also described.
Patent WO-2020081957-A1 (WO)
Title: Magnetic delivery system and hydrogel fixative for therapeutic cells
Inventor: VORP DAVID
IPC: A61L27/52
Filed: 2019-10-18
Abstract: A method of delivering cells to a target tissue is provided comprising depositing a hydrogel pre-gel comprising magnetic particle-loaded cells to the target tissue and, prior to or during gelation of the hydrogel, drawing the magnetic particle-loaded cells to the tissue with a magnetic field, followed by gelation of the hydrogel to lock the cells in place on the tissue. The cells may be mesenchymal stem cells, such as adipose-derived mesenchymal stem cells, and the target tissue may be adventitial tissue of an aneurysm in a blood vessel. Also provided are devices useful in the method.
Patent WO-2020086499-A1 (WO)
Title: A uav-borne, high-bandwidth, lightweight point sensor for quantifying greenhouse gases in atmospheric strata
Inventor: SMITH BRENDAN JAMES
IPC: G01N21/31
Filed: 2019-10-22
Abstract: Systems, devices, and methods for a gas sensor (102) comprising one or more optical cells (110, 112, 114); a processor (136) having addressable memory (138), the processor (136) configured to: detect gas from the one or more optical cells (110, 112, 114) of the gas sensor (102), where the detected gas is one or more of: methane, carbon dioxide, hydrogen sulfide, water, ammonia, sulfur oxides, and nitrogen; record data corresponding to the detected gas, where the recorded data comprises at least one of: an ambient temperature from a temperature sensor (124), an ambient pressure from a pressure sensor (122), an aerial vehicle telemetry (106), and an aerial vehicle location from a global positioning system (GPS) (108); and generate a map of atmospheric greenhouse gas concentration on a map based on the detected gas and the recorded data.
Patent WO-2020131216-A1 (WO)
Title: Revêtement de face arrière pour substrat transparent
Inventor: DOSHAY SAGE
IPC: C23C16/34
Filed: 2019-10-25
Abstract: Des modes de réalisation de la présente invention concernent le traitement de semi-conducteurs. Plus spécifiquement, des modes de réalisation de la présente invention concernent le traitement de substrats transparents. Un film est déposé sur une face arrière du substrat transparent. Une épaisseur du film est déterminée de telle sorte que le film réfléchit des longueurs d'onde particulières de lumière et empêche sensiblement la déformation en arc du substrat. Le film fournit une interférence constructive aux longueurs d'onde particulières de la lumière.
Patent WO-2020101881-A1 (WO)
Title: Connector interface assembly
Inventor: DE LA FUENTE VALENTIN
IPC: H04M1/02
Filed: 2019-10-29
Abstract: In a general aspect, an apparatus can include a grounding shell having a lumen defined therethrough. The lumen can be aligned along an axis and configured to receive a connector plug receptacle from a first side of the apparatus. The apparatus can also include a trim ring having a lumen defined therethrough. The lumen of the trim ring can be aligned along the axis and configured to receive a connector plug corresponding with the connector plug receptacle from a second side of the apparatus. The second side can be opposite the first side. The apparatus can further include a mounting plate configured to couple the apparatus with at least one of a circuit board or a housing of an electronic device. The grounding shell, the trim ring and the mounting plate can be monolithically integrated.
Patent WO-2020092634-A1 (WO)
Title: System for estimating primary open-angle glaucoma likelihood
Inventor: ZANGWILL LINDA
IPC: A61B3/00
Filed: 2019-10-30
Abstract: This application describes a system to estimate the likelihood of glaucoma from fundus images. The system may include receiving an optic nerve head region of an original image. A variation to the optic nerve head region are applied. A first primary open angle glaucoma likelihood estimate based on the first varied optic nerve head region is generated using a trained convolutional neural network. A second primary open angle glaucoma likelihood estimate based on the second varied optic nerve head region is generated using a trained convolutional neural network. The first primary open angle glaucoma likelihood estimate and the second primary open angle glaucoma likelihood estimate are combined into a final primary open angle glaucoma likelihood estimate. The final primary open angle glaucoma likelihood estimate is presented to a user.
Patent WO-2020112320-A1 (WO)
Title: Last-level collective hardware prefetching
Inventor: MICHELOGIANNAKIS GEORGIOS
IPC: G06F12/0862
Filed: 2019-11-06
Abstract: A last-level collective hardware prefetcher (LLCHP) is described. The LLCHP is to detect a first off-chip memory access request by a first processor core of a plurality of processor cores. The LLCHP is further to determine, based on the first off-chip memory access request, that first data associated with the first off-chip memory access request is associated with second data of a second processor core of the plurality of processor cores. The LLCHP is further to prefetch the first data and the second data based on the determination.
Patent WO-2020097557-A1 (WO)
Inventor: JUDGE SCOTT
IPC: F04F13/00
Filed: 2019-11-08
Abstract: La présente invention concerne des dispositifs d'échange de pression, des systèmes, ainsi que des procédés associés pouvant comprendre un réservoir, un piston, un dispositif de type soupape et un ou plusieurs capteurs pour surveiller la position du piston dans le réservoir.
Patent WO-2020102715-A1 (WO)
Inventor: FOWLER DANIEL HARDING
IPC: A61K35/17
Filed: 2019-11-15
Abstract: The present disclosure provides methods for producing de-differentiated T cells, said de- differentiated T cells, populations thereof and compositions thereof.
Patent WO-2020117495-A1 (WO)
Inventor: MANN JASON
IPC: C08F210/10
Filed: 2019-11-22
Abstract: Although polyolefin elastomers are widely employed commodity polymers, there are shortcomings of this class of polymers for certain applications. For example, the rheological properties of some polyolefin elastomers may be insufficient to provide the green strength or low shear viscosity necessary to form stable foams, or to provide sufficient viscosity modification effects when present in a solvent. Cationomeric modification of polyolefin elastomers may alleviate these difficulties. Such polyolefin elastomers may feature a random cationomeric polyolefin copolymer comprising at least a first monomer and a second monomer, in which the first monomer is a neutral monomer and the second monomer has a side chain bearing a cationic moiety. The polyolefin elastomers may be present in foamed polyolefin compositions comprising a gas component and/or in liquid compositions comprising a solvent in which the polyolefin elastomer is dissolved.
Patent WO-2020117507-A1 (WO)
Title: Training speech recognition systems using word sequences
Inventor: THOMSON DAVID
IPC: G10L15/06
Filed: 2019-11-22
Abstract: A method may include obtaining first audio data of a communication session between a first device and a second device, obtaining a text string that is a transcription of the first audio data, and selecting a contiguous sequence of words from the text string as a first word sequence. The method may further include comparing the first word sequence to multiple word sequences obtained before the communication session and in response to the first word sequence corresponding to one of the multiple word sequences, incrementing a counter of multiple counters associated with the one of the multiple word sequences. The method may also include deleting the text string and the first word sequence and training and after deleting the text string and the first word sequence, training a language model of an automatic transcription system using the multiple word sequences and the multiple counters. The method is for estimating n-gram statistics based on the communication and provides data protection mechanisms for private data.
Patent WO-2020117654-A1 (WO)
Inventor: LANG BRADLEY
IPC: C07C211/35
Filed: 2019-12-02
Abstract: L'invention concerne des sels ésylate et salicylate de cis-N-cyclohexyl-N-éthyl-3-(3-chloro-4-cyclohexylphényl)prop-2-énylamine et leur composition pharmaceutique. L'invention concerne également l'utilisation de sels ésylate et salicylate de cis-N-cyclohexyl-N-éthyl-3-(3-chloro-4-cyclohexylphényl)prop-2-énylamine et de leur composition pharmaceutique dans le traitement de troubles liés à la myéline.
Patent WO-2020113237-A1 (WO)
Inventor: ABRAHAM JIM
IPC: G16H20/70
Filed: 2019-12-02
Abstract: Comprehensive molecular profiling provides a wealth of data concerning the molecular status of patient samples. Such data can be compared to patient response to treatments to identify biomarker signatures that predict response or non-response to such treatments. This approach has been applied to identify biomarker signatures that strongly correlate with response of colorectal cancer patients to FOLFOX. Described herein are data structures, data processing, and machine learning models to predict effectiveness of a treatment for a disease or disorder of a subject having a particular set of biomarkers, as well as an exemplary application of such a model to precision medicine, e.g., to methods for selecting a treatment based on a molecular profile, e.g., a treatment comprising administration of 5-fluorouracil/leucovorin combined with oxaliplatin (FOLFOX) or with irinotecan (FOLFIRI).
Patent WO-2020142155-A1 (WO)
Inventor: BAGGETT JOHN
IPC: H01L21/687
Filed: 2019-12-04
Abstract: A workpiece processing system has a chamber with one or more chamber walls defining surfaces enclosing a chamber volume. One or more chamber wall heaters selectively heat the chamber walls to a chamber wall temperature. A workpiece support within the chamber selectively supports a workpiece having one or more materials having a respective condensation temperature, above which, the one or more materials are respectively in a gaseous state. A heater apparatus selectively heats the workpiece to a predetermined temperature. A controller heats the workpiece to the predetermined temperature by controlling the heater apparatus, heating the one or more materials to respectively form one or more outgassed materials within the chamber volume. The controller further controls the chamber wall temperature by controlling the chamber wall heaters, where the chamber wall temperature is greater than a condensation temperature of the outgassed materials, preventing condensation of the outgassed material on the chamber surfaces.
Patent WO-2020154239-A1 (WO)
Inventor: WEISBRUCH ERIC BERNARD
IPC: B62D55/21
Filed: 2020-01-21
Abstract: L'invention concerne un joint de charnière de chenille (200) qui comprend un premier maillon de chenille (202), un second maillon de chenille (226), une broche de chenille (252) disposée dans un trou (222) du premier maillon de chenille (202), une bague interne (254) qui est disposée dans un alésage (242) du second maillon de chenille (226) et qui est rotative par rapport à la broche de chenille (252), une bague externe (256) qui est disposée autour de la bague interne (254), qui peut tourner par rapport à la bague interne (254) et qui comprend une face d'extrémité de bague externe (258), et un premier ensemble d'étanchéité à fluide (260) en contact avec la face d'extrémité de bague externe (258) et le second maillon de chenille (226).