baber/WOPTO huggingface dataset:
Patent AU-2019200897-A1 (AU)
Title: Compositions and methods for improving nanopore sequencing
Inventor: GUNDLACH JENS H
IPC: G01N27/26
Filed: 2019-02-08
Abstract: COMPOSITIONS AND METHODS FOR IMPROVING NANOPORE The present disclosure provides methods and reagents for improving nanopore- based analyses of polymers. Specifically, the disclosure provides a method of analyzing a polymer that includes a polymer analyte that contains an end domain that has at least one charged moiety. The disclosure also provides a method of increasing the interaction rate between a polymer analyte and a nanopore, wherein the polymer analyte contains an end domain that has at least one charged moiety. The disclosure also provides compositions for use with the described methods, including adapter compositions that contain charged moieties, such as phosphate or sulfate groups, and that are configured to being linked to an polymer analyte domain.
Patent AU-2019203111-A1 (AU)
Title: Manufacturing of multi-dose injection ready dendritic cell vaccines, combination therapies for blocking HER2 and HER3, and estrogen receptor positive HER2 breast cancer therapy
Inventor: CZERNIECKI BRIAN J
IPC: C12N5/00
Filed: 2019-05-02
Abstract: Abstract The present embodiments relate to an FDA- approved injectable multi-dose antigen pulsed dendritic cell (DC) vaccine. In one embodiment, the activated antigen-loaded DC vaccine comprises an initial immunizing dose and multiple "booster" doses. Also provided is a method of blocking both HER-2 and HER-3 as a treatment in causing permanent tumor senescence in HER 2 expressing breast cancers. Also provided is combination anti-estrogen therapy and anti-HER2 dendritic call vaccination for ERP°S/HER2PS DCIS breast cancer patients. z L z t5 L
Patent AU-2019203378-A1 (AU)
Title: Topical sanitizing formulations and uses thereof
Inventor: COZEAN JESSE
IPC: A61K31/085
Filed: 2019-05-14
Abstract: Abstract Several embodiments disclosed herein relate to formulations having antimicrobial and/or sanitizing effects, and uses of the same. In particular, the formulations and methods of using same provide, in several embodiments, an immediate and a persistent antimicrobial effect against a broad spectrum of microorganisms. 0 °100 c 80 C£)60 a) a) a) 2 min 1 hour 6 hour 0 EtOH Antiseptic Elapsed Time 0 Antiseptic Lotion
Patent AU-2019204599-A1 (AU)
Title: Corrosion protection with al/zn-based coatings
Inventor: SMITH ROSS MCDOWALL
IPC: C23C2/12
Filed: 2019-06-28
Abstract: Red rust staining of Al/Zn coated steel strip in "acid rain" or "polluted" environments can be minimised by 5 forming the coating as an Al-Zn-Si-Mg alloy coating with an OT:SDAS ratio greater than a value of 0.5:1, where OT is the overlay thickness on a surface of the strip and SDAS is the measure of the secondary dendrite arm spacing for the Al-rich alpha phase dendrites in the coating. Red 10 rust staining in "acid rain" or "polluted" environments and corrosion at cut edges in marine environments can be minimised in Al-Zn-Si-Mg alloy coatings on steel strip by selection of the composition (principally Mg and Si) and solidification control (principally by cooling rate) and 15 forming Mg2Si phase particles of a particular morphology in interdendritic channels. 11d81688 1 (GH:attrs) 78d70.AL. . 28 /06/19 Washed (83 mt) _ 3 Mg(%N Figure 1: Reduction in the level of edge undercutting for painted, metallic coated steel strip in accordance with the present invention, for washed exposure in a severe marine environment.
Patent AU-2019205090-A1 (AU)
Title: Misfolded TDP-43 binding molecules
Inventor: SEREDENINA TAMARA
IPC: C07K16/18
Filed: 2019-01-04
Abstract: The present invention is in the field of transactive response DNA binding protein with a molecular weight of 43 kDa (TARDB or also TDP-43). The invention relates to TDP-43 specific binding molecules, in particular to anti-TDP-43 antibodies or an antigen-binding fragment or a derivative thereof and uses thereof. The present invention provides means and methods to diagnose, prevent, alleviate and/or treat a disorder and/or abnormality associated with misfolded TDP-43 including but not limited to frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD, sporadic and familial), and/or Parkinson's disease (PD). The present invention provides modified conformation-specific antigenic peptides and peptide fragments derived from the TDP-43 protein and the antibodies obtainable by said peptides or fragments for use in the diagnosis, prevention, alleviation and/or treatment of TDP-43-related disorders and/or abnormalities.
Patent AU-2019209043-A1 (AU)
Title: Tennis wall
Inventor: LENFERS ALEXANDER
IPC: A63B69/00
Filed: 2019-01-11
Abstract: The present invention relates to a tennis wall (100), comprising - a frame that can be erected on the ground (101) and a cloth (102) stretched taut in said frame (101), wherein the cloth (102) is stretched such that a level cloth surface (104) is formed and that a tennis ball hitting the cloth surface (104) rolls or slides up the cloth surface (104) and then rolls or slides down again, characterised in that a recess (105) is provided on the upper end (103) of the cloth (102), the recess (105) being designed and positioned such that a tennis ball, once it has rolled or slid up the cloth surface (104), then enters the recess (105), subsequently rolls or slides out of the recess (105) again and only then rolls or slides down the cloth surface (104). The invention also relates to the use of this tennis wall as an aid in tennis training.
Patent AU-2019229450-A1 (AU)
Title: Controlling runtime access to application programming interfaces
Inventor: TROFIN MIRCEA
IPC: G06F9/44
Filed: 2019-09-13
Abstract: A system, the system comprising: a processor; 5 system memory coupled to the processor and storing instructions configured to cause the processor to: determine that a default visibility into a programming interface is to be altered, the default visibility defining other software components that can access the programming interface at runtime based at least in part on a type of the programming interface, the 10 default visibility including not permitting dynamic access to a non-public programing interface; and attach an additional attribute to the programming interface to override the default visibility into the programming interface, the additional attribute indicating that runtime dynamic access requests to the programming interface are to be evaluated using the 15 additional attribute to permit dynamic access to the non-public programing interface. Accessing a set of application programming interfaces (APIs) combined in a library, the set of application programming interfaces (APIs) including one or more public application programming interfaces (APIs) and one or more non-public application programming interfaces (APIs) Identifying an application programming interface (API) from among the set of application programming interfaces (APIs) for which the default visibility provided to dynamic access requests are to be altered Altering the default visibility into the application programming interface (API) to an altered visibility by applying an attribute to the application programming interface (API), the attribute indicating to the runtime environment at runtime that dynamic access requests are to be provided the altered visibility into the application programming interface (API) Fig. 2
Patent AU-2019233949-A1 (AU)
Title: Impact absorption structure comprising an impact receiving component and an energy dissipation component
Inventor: TEAR GARETH
IPC: F41H5/04
Filed: 2019-03-12
Abstract: An impact absorption structure (1) is provided. The impact absorption structure (1) comprises an impact receiving component (3), capable of, after receiving an initial impact shockwave, separating that shockwave into at least a first shockwave (Sll) and a second shockwave (S122), time-spaced from the first shockwave (Sll). The impact absorption structure (1) also comprises an energy dissipation component (5) adjacent to the impact receiving component (3), such that the time-spaced shockwaves (Sll, S122) can be passed across an interface from the impact receiving component (3) to the energy dissipation component (5). The energy dissipation component (5) comprises a chemical element or compound such as calcite exhibiting a first displacive phase change from a first phase to a second phase (52) upon experiencing the first shockwave (Sll), a second displacive phase from the second phase (52) to a third phase (53) upon experiencing the second, later shockwave (S122), and a third displacive phase change from the third, or a later, phase (53) to the first phase upon unloading after the second shockwave (S122), the compound thereby exhibiting a hysteresis cycle in which elastic energy is dissipated.
Patent AU-2019240582-A1 (AU)
Title: A downhole coupling mechanism
Inventor: RADTKE CAMERON
IPC: E21B17/046
Filed: 2019-10-01
Abstract: A downhole coupling mechanism for use in downhole tools that find application in wells 
exploited by a hydraulic refracturing process. The downhole coupling mechanism connects first 
and second tubular sections via a tensile load arrangement of wires located in complimentary 
grooves, a torque arrangement of interlocking lugs and notches on opposite ends, and a seal 
arrangement. The downhole coupling mechanism provides a thin walled coupling where a screw
threaded connection could not achieve the required tensile load, torque and sealing properties 
needed. Embodiments of a thin walled anchor and packer including the downhole coupling 
mechanism are described.
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1
Patent AU-2019250141-A1 (AU)
Title: Methods of delivering oligonucleotides to immune cells
Inventor: NOVOBRANTSEVA TATIANA
IPC: A01N43/04
Filed: 2019-10-16
Abstract: The invention relates to the field of delivery of nucleic acid-based agents to immune cells.
Patent AU-2019252063-A1 (AU)
Title: Anaerobic threshold estimation method and device
Inventor: HIGUCHI YUICHI
IPC: A61B5/0245
Filed: 2019-04-10
Abstract: This anaerobic threshold estimation method includes: a first acquisition step of acquiring the exercise intensity of an exercise performed by a subject; a second acquisition step of acquiring electrocardiographic waveforms of the subject performing the exercise; a third acquisition step of acquiring a predetermined feature amount from the acquired electrocardiographic waveforms; and an estimation step of estimating an AT of the subject on the basis of the relationship between the predetermined feature amount and the acquired exercise intensity. The anaerobic threshold estimation method is characterized in that the estimation step estimates the AT of the subject on the basis of the exercise intensity that corresponds to an inflection point of the change in the predetermined feature amount relative to the acquired exercise intensity.
Patent AU-2019256414-A1 (AU)
Title: Swash plate-type axial piston pump
Inventor: KRONPASS MANUEL
IPC: F03C1/40
Filed: 2019-03-29
Abstract: The invention relates to a swash plate-type axial piston pump, in particular for hydraulic systems, comprising a cylinder drum (3) which is rotated about a rotational axis (7) in a pump housing (1) and in which pistons (9) are arranged in an axially movable manner, the piston actuation ends that can be accessed from outside the cylinder drum (3) being supported at least indirectly on a swash plate (15), wherein the swash plate can be pivoted into a desired inclination angle relative to the rotational axis (7) by means of an adjustment device (21) in order to adjust the stroke of the piston (9) and thus the fluid system pressure generated thereby, and the adjustment device has at least one pivot lever (23) which can be deflected in at least one direction and restored by means of an adjustment drive and which has a respective actuation piston (35) in at least one hydraulically actuatable actuation cylinder (31, 43), said actuation piston engaging on an attachment point (29) of the pivot lever (23) at one end. The invention is characterized in that the at least one actuation piston (35, 47) has a guide surface (73) at the end opposite the attachment point (29), said guide surface being a single-piece part of the actuation piston (35, 47) and contacting a paired guide surface (33, 45) of the actuation cylinder (31, 43), and at least one adjustment means (75, 70, 59) is provided which aligns the respective position of each guide surface (73; 33, 45) relative to each other.
Patent AU-2019290725-A1 (AU)
Title: Measurement control method and apparatus, and terminal device
Inventor: TANG HAI
IPC: H04W24/10
Filed: 2019-06-21
Abstract: A measurement control method and apparatus, and a terminal device. A measurement start between MN and SN nodes can be coordinated. The method comprises: the terminal device receives first configuration information sent by a first node and second configuration information sent by a second node (401); in the case that the terminal device determines on the basis of the first configuration information and/or the second configuration information that the first node receives measurement request configuration information from the second node: if the terminal device activates a first measurement function of a second node side, the terminal device can activate a first measurement function of a first node side, wherein if the first measurement function is in an activated state, the terminal device performs measurement of a serving cell, but does not perform adjacent cell measurement between an inter-frequency cell, a co-frequency cell, and inter-RAT (402).
Patent AU-2019310299-A1 (AU)
Title: Method and apparatus for labeling of support structures
Inventor: BEACH ROBERT E
IPC: B65C9/46
Filed: 2019-05-30
Abstract: An apparatus for labeling support structures includes: a chassis having a locomotive assembly, and supporting a label generator and an effector assembly with an end movable relative to the chassis and carrying a label manipulator with an image sensor; a controller coupled to the locomotive assembly, label generator, effector assembly and label manipulator, and configured to: obtain label placement data defining a location relative to a support structure reference feature for replacement of a previous label with a new label; control the locomotive assembly to travel to the support structure; detect the reference feature via image data captured at the image sensor; control the effector assembly to place the label manipulator at the location relative to the reference feature; control the effector assembly and the label manipulator to remove and discard the previous label, retrieve the new label from the label generator, and place the new label at the location.
Patent AU-2019345320-A1 (AU)
Title: Methods of treating cancer
Inventor: SATHEKGE MIKE
IPC: A61K51/08
Filed: 2019-09-20
Abstract: The disclosure pertains to drug delivery conjugates for targeted therapy. The disclosure relates to methods of treating PSMA expressing cancers with a combination of compounds of the formulas I-Lu or Ia-Lu, and I-Ac or Ia-Ac. The disclosure also relates to methods of treating PSMA-expressing cancers with a combination of compounds of the formulas I-Lu or Ia-Lu, and I-Ac or Ia-Ac in patients where stable disease results after treatment with a combination of compounds of the formulas I-Lu or Ia-Lu, and I-Ac or Ia-Ac.
Patent AU-2019362745-A1 (AU)
Title: Absorption and filtration media
Inventor: KELLY ROBERT JAMES MCCLELLAND
IPC: B01D53/02
Filed: 2019-10-18
Abstract: Disclosed are keratin fibre cellular components, specifically keratin fibre cuticle and cortical cells, and their use as absorption and filtration media, and in thermal insulation materials. The keratin fibre cellular components may be oxidised. The keratin fibre cellular components have improved absorbency and filtration capacity compared to the source keratin fibres. The keratin fibre cellular components may be used in, for example, various products for passive absorption and active filtration of gas or liquid media.
Patent AU-2019389858-A1 (AU)
Title: Quantum controller with modular and dynamic pulse generation and routing
Inventor: COHEN YONATAN
IPC: H03K3/38
Filed: 2019-10-25
Abstract: A quantum controller comprises raw pulse generation circuitry, pulse modification circuitry, and output management circuitry. The raw pulse generation circuitry is operable to generate a raw output pulse. The output management circuitry is operable to route one or more output pulses onto a selected one or more signal paths based on to which one or more of a plurality of elements of a quantum processor the one or more output pulses are to be sent. The pulse modification circuitry is operable to select pulse modification settings to use for processing of the raw output pulse, wherein the selection is based on which of the signal paths are selected and/or to which elements of a quantum processor the pulses are to be sent. The pulse modification circuitry is operable to process the raw pulse using the selected pulse modification settings to generate the output pulses.
Patent AU-2019392683-A1 (AU)
Title: Combination therapies
Inventor: CHRISTENSEN JAMES GAIL
IPC: A61K31/44
Filed: 2019-12-05
Abstract: The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a SHP-2 inhibitor and a KRAS G12C inhibitor of Formula (I), Formula I-A or Formula I-B, pharmaceutical compositions comprising a therapeutically effective amounts of the inhibitors, kits comprising the compositions and methods of use therefor.
Patent AU-2019392925-A1 (AU)
Title: Humidity activated compositions for release of antimicrobials
Inventor: PRESLAR ADAM TRUETT
IPC: A01N31/08
Filed: 2019-12-06
Abstract: Compositions for humidity activated release of antimicrobials, and associated methods, are generally provided. Certain aspects are related to compositions comprising delivery materials (e.g., silica-based delivery materials) and antimicrobials. The delivery material and the antimicrobial can be associated with each other such that when humidity is introduced to the composition, at least a portion of the antimicrobial is released from the composition. Methods of releasing antimicrobials from compositions are also provided. Certain methods comprise allowing antimicrobial to be released from a composition such that the antimicrobial suppresses the actions or adverse effects of pathogens or pests.
Patent AU-2019406923-A1 (AU)
Title: Rock drill bit for percussive drilling
Inventor: BRUANDET OLIVIER
IPC: E21B4/14
Filed: 2019-11-27
Abstract: The present disclosure relates to a rock drill bit 14 for percussive drilling hammer 11 positioned at the cutting end of the hammer. A head 19, an elongated shank 17 connected to the head 19 at a front end of the bit 14, a head-shank transition area 32 where the head 19 connects to the shank 17, an anvil 22 at the rear end of the shank 17 for receiving the impact of the piston 13, a plurality of buttons 20 provided at the front face 21 of the head 19 configured to engage the material to be crushed in the intended direction of drilling, a plurality of flushing passages extending through the head and having at least one opening 31 at the front face 21 of the head 19, and the angle formed between the head 19 and the shank 17 at the head-shank transition area 32 is greater than 100 degrees.
Patent AU-2019428624-A1 (AU)
Title: Die for a printhead
Inventor: GARDNER JAMES MICHAEL
IPC: B41J2/14
Filed: 2019-02-06
Abstract: A die for a printhead is described herein. The die includes a number of fluid feed holes disposed in a line parallel to a longitudinal axis of the die, wherein the fluid feed holes are formed through a substrate of the die. A number of fluidic actuators are proximate to the fluid feed holes, to eject fluid received from the fluid feed holes A number of field-effect transistors are parallel to the fluid feed holes, where each of the fluidic actuators is powered by an associated field effect transistor. Logic circuitry to actuate the plurality of field-effect transistors is disposed on the die on an opposite side of the fluid feed holes from the field-effect transistors, wherein traces, disposed between the fluid feed holes, electrically couple the logic circuitry to the field-effect transistors. The die has a repeating structure comprising one fluid feed hole, two fluidic actuators, and two field-effect transistors placed at an interval of two times a dot pitch in a line along the die.
Patent AU-2019460126-A1 (AU)
Title: Expandable metal gas lift mandrel plug
Inventor: EVERS RUTGER
IPC: E21B43/12
Filed: 2019-08-06
Abstract: Disclosed herein are aspects of a gas lift mandrel plug for use in a wellbore. In one embodiment, a gas lift mandrel plug may comprise an elongate member having a proximal end and a distal end, wherein the elongate member comprises a metal sealant configured to expand in response to hydrolysis, and wherein the elongate member is configured to seal a side pocket of a wellbore tubular in response to hydrolysis.
Patent AU-2020200791-A1 (AU)
Title: Non-dairy formulae
Inventor: KESLER URIEL
IPC: A23L33/15
Filed: 2020-02-04
Abstract: The present invention is directed to non-dairy almond based formulae for the preparation of infant or toddler formula or other types of supplemental or functional food.
Patent AU-2020202558-A1 (AU)
Title: Controller and control system
Inventor: AZUMA TAN
IPC: G06Q50/02
Filed: 2020-04-16
Abstract: Abstract In order to provide an farming schedule matching a growing environment for crops and increase reliability of farming support, 5 the present invention comprises: an index value calculation unit that calculates index values at which the growth of crops is hindered, during a period including at least an observation period in which the effects of farming work performed in order to grow crops are observed; and a schedule generation unit that, in order to 10 reduce the index values calculated by the index value calculation unit, generates a schedule for farming work performed on crops during a prescribed farming period being a period prior to the observation period.
Patent AU-2020212111-A1 (AU)
Title: Compound for inhibiting PGE2/EP4 signaling transduction inhibiting, preparation method therefor, and medical uses thereof
Inventor: DENG YONGQI
IPC: A61P35/00
Filed: 2020-01-16
Abstract: A compound of formula (I), a preparation method therefor, a pharmaceutical composition containing a derivative thereof, and the therapeutic uses thereof, especially inhibiting PGE2/EP4 signalling transduction and the uses thereof for treating cancer, acute or chronic pain, migraine, osteoarthritis, rheumatoid arthritis, gout, bursitis, ankylosing spondylitis, primary dysmenorrhea, tumour or arteriosclerosis.
Patent AU-2020220210-A1 (AU)
Title: Methods for treating ocular diseases
Inventor: SALLSTIG PETER
IPC: A61P27/02
Filed: 2020-08-21
Abstract: C:\Interwovn\NRPortbl\DCC\DAR\18170646 .docx-I/ 122018 
Abstract 
A method is provided for reducing the treatment burden for patients who have an 
intraocular neovascular disorder, the method comprising administering a therapeutically 
effective amount of VEGF antagonist on a dosing schedule that includes treatment intervals of 
8 and/or 12 weeks.
WO 2016/073918 PCT/US2015/059575 
FIG.1 
Week 0 4 8 12 16 20 24 28 32 36 40 44 48 52 56 60 64 68 72 76 80 84 88 92 96 
RT11258 
RT11258 
q8 
R'l 258 
Disease activity assessment =RTH258 injection 
q12 = treatment every 12 weeks qS = treatment every 8 weeks switch to qS if any disease activity assessment criterion met 
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