baber/WOPTO huggingface dataset:
Patent CO-6321253-A2 (CO)
Title: Formas cristalinas y dos formas solvatadas de sales de acido lactico de la 4- amino-5- fluoro-3-[5-(4-metil-piperazin-1-il)1h-bencimidazol-2-il]-quinolin-2(1h)-ona
Inventor: GIRON DANIELLE
IPC: C07D401/14
Filed: 2010-10-19
Abstract: Formas cristalinas o polimorfos de las sales de ácido láctico de la 4-amino-5-fluoro-3-[5-(4-metil-piperazin-1-il)-1H-bencimidazol-2-il]quinolin-2(1H)-ona, así como métodos para la elaboración de las mismas, composiciones farmacéuticas que comprenden las mismas, y métodos de tratamiento utilizando las mismas.
Patent CO-6321165-A2 (CO)
Title: Inhibidores ciclicos de 11 beta -hidroxiesteroide deshidrogenasa 1
Inventor: CLAREMON DAVID A
IPC: A61P19/10
Filed: 2010-11-10
Abstract: Esta invención se refiere a nuevos compuestos de la Fórmula lk, lm1, lm2, lm5, ln1, ln2, ln5, lo1, lo2, lo5, Ip1, Ip3, a sales farmacéuticamente aceptables de los mismos y a composiciones farmacéuticas de los mismos, que son útiles para el tratamiento terapéutico de enfermedades asociadas con la modulación o inhibición de 11ß-HSD1 en mamíferos. La invención también se refiere a composiciones farmacéuticas de los nuevos compuestos y métodos para su uso en la reducción o control de la producción de cortisol en una célula o la inhibición de la conversión de cortisona en cortisol en una célula.
Patent CO-6341581-A2 (CO)
Title: Derivados de heteroarilo como inhibidores de dgat1
Inventor: FORSTER CORNELIA JUTTA
IPC: A61P3/10
Filed: 2011-02-18
Abstract: La invención se refiere a los compuestos de la fórmula (I):en donde A es un heteroarilo opcionalmente sustituido, útiles para el tratamiento de los trastornos mediados por acil-transferasa de acil-CoA-diacil-glicerol 1 (DGAT1), por ejemplo, trastornos metabólicos. La invención también proporciona métodos para el tratamiento de estos trastornos, y los compuestos y composiciones etc. para su tratamiento.
Patent CO-6382141-A2 (CO)
Title: Uso de 7-cloro-n,n,5-trimetil-4-oxo-3-fenil-3,5-dihidro-4h-piridazino[4,5-b]indol-1-acetamida como biomarcador de los niveles del receptor perisferico de benzodiazepinas
Inventor: BENAVIDES JESUS
IPC: A61K51/04
Filed: 2011-04-27
Abstract: Uso de una forma radiomarcada de 7-cloro-N,N, 5-trimetil-4-oxo-3-fenil-3,5-dihidro-4H-piridazino[4,5-b]indol-1-acetamida como biomarcador para la detección, en un individuo, de los niveles de PBR asociados con estados normales y patológicos. Método para la detección de los niveles de PBR asociados con estados normales y patológicos. Kit de diagnóstico.
Patent CO-6561792-A2 (CO)
Title: Recipiente termofijo
Inventor: HARRIS IVAN
IPC: B65D1/02
Filed: 2012-07-10
Abstract: Un recipiente termo fijo que comprende una porción base, una porción de hombro y una porción de pared lateral que se extiende desde la porción de hombro a la porción base, la porción de hombro, la porción de pared lateral y la porción base cooperan para definir una cámara de receptáculo dentro del recipiente en el cual puede llenarse producto. Una pluralidad de paneles de vacío se colocan equidistantes respecto a la porción de pared lateral. Una pluralidad de superficies de transición se coloca entre adyacentes de la pluralidad de paneles de vacío y separados hacia afuera respeto a estos. La pluralidad de paneles de vacío y la pluralidad de superficies de transición cooperan para ser plegables hacia adentro desde un primer diámetro exterior a un segundo diámetro exterior, en respuesta cuando menos a fuerzas de vacío interno.
Patent CO-6602168-A2 (CO)
Title: Composicion de pigmentos solubles en agua o en solventes organicos
Inventor: BROGGI GIOVANNI
IPC: C09D7/47
Filed: 2012-09-19
Abstract: Se describe una composición consistente en: (a) al menos un pigmento orgánico u inorgánico; y (b) al menos un agente de dispersión; y al menos un componente seleccionado de: (c) agentes de aceleración de solubilización; (d) rellenos inorgánicos; (e) aglutinantes; (f) resinas acrílicas, de aldehído o cetona; (g) agentes reológicos; (h) antiespumantes. Esta composición preferentemente tiene forma de tabletas y tiene las siguientes ventajas en comparación con las composiciones conocidas en la técnica: pigmentación de las pinturas en forma eco-compatible; compatibilidad universal con los diferentes sistemas de pintura; extremadamente corta duración del proceso de pigmentación de la pintura; transporte y dosificación fáciles; proceso de pigmentación de pintura de bajo costo; proceso de producción simple y de bajo costo.
Patent CO-6721039-A2 (CO)
Title: Bifenoles halogenados como agentes antibacterianos
Inventor: SUBRAMANYAM RAVI
IPC: C07C39/373
Filed: 2013-06-21
Abstract: Se describen en la presente los compuestos de la Fórmula (I) : o una sal de los mismos; en donde: R1 y R5 son independientemente seleccionados de H, OH y alcoxi; R2-R4 y R6-R8 son independientemente seleccionados de H, OH, F, Cl, Br, y I; R9 y R10 son independientemente seleccionados de H, alquilo, alquenilo, alquinilo, y arilo; con la condición de que: al menos uno de R1 y R5 sea OH o alcoxi; y al menos uno de R2-R4 y R6-R8 sea F, Cl, Br o I; las composiciones que comprenden dichos compuestos; y métodos de fabricación y uso de las mismas.
Patent EP-1000822-A2 (EP)
Inventor: BOEHMLER KLAUS
IPC: F16F7/12
Filed: 1996-03-07
Abstract: The method involves deriving a parameter representing the occupant's body size or wt. and adjusting the level of the force limitation depending on this parameter. For a system with an inflatable restraint element, the force level is set so that force characteristic decreases in a region of displacement after which contact between the safety belt and inflatable element is anticipated. An Independent claim is also included for a force limiter for a safety belt system.
Patent EP-1039329-A2 (EP)
Inventor: YOSHIOKA YASUE
IPC: C09K19/02
Filed: 2000-03-10
Abstract: A liquid crystal composition comprising
anti-ferroelectric liquid crystal compound (1)
selected from liquid crystal compounds of the
formula (1) and a ferrielectric liquid crystal
compound (2) or a racemic compound (2') thereof,
wherein (a) the compositional ratio of the anti-ferroelectric
liquid crystal compound (1) and the
ferrielectric liquid crystal compound (2) or the
racemic compound (2') thereof is in the range of
from a value which is on the anti-ferroelectric
phase side and is apart from a boundary
compositional ratio by 5 mol% to a value which is on
the ferrielectric phase side and is apart from the
boundary compositional ratio by 25 mol%, wherein the
boundary compositional ratio is obtained on the
basis of a liquid crystal phase diagram prepared on
the basis of conoscopic image observations obtained
by changing the mixing ratio of the anti-ferroelectric
liquid crystal compound (1) and the
ferrielectric liquid crystal compound (2) or the
racemic compound (2') thereof, (b) in an optical
response to an applied voltage, the liquid crystal
composition exhibits an optical response which is
symmetrical in a positive voltage region and a
negative voltage region and which is free of
hysteresis or involves a small hysteresis, and (c)
the liquid crystal composition has excellent
alignment stability.,
   
     The novel liquid crystal composition of
the present invention is almost free from sticking,
is excellent in alignment and alignment stability
and exhibits a V-letter-shaped optical response so
that it can give a highly reliable active matrix
liquid crystal display device.
Patent EP-1050217-A2 (EP)
Inventor: HEYDE HANS
IPC: A23G3/22
Filed: 2000-04-27
Abstract: A unit (17) assists return of excess coating mass (8) from the run-off sheet (9). This includes moving metal scraper blades (18). These extend generally transversely towards the sheet, with a minimum clearance (22) from it Preferred features: Clearance is about 5 mm from the surface facing the run-off sheet. The blades are driven intermittently continuously to contact surplus coating mass reaching the sheet. Their path (21) is rectangular and their width exceeds the mean mass height on the run-off sheet. Rectangular motion assures separation from the mass during the back stroke. Scrapers are assem in a pattern on longitudinal beams (19). They are driven by pneumatic cylinders phased to describe the rectangular path. In a variant, a direct mechanical drive is employed. Only part of the sheet is scraped in this way. Scrapers extend at an angle of ab 30 degrees with respect to the run-off sheet.
Patent EP-1055611-A2 (EP)
Inventor: STERNER MARION
IPC: B29C65/00
Filed: 2000-05-18
Abstract: A composite film of flexible material which comprises at least two base
films (11,12,39,41) which are mutually coupled in partial regions and form, in the
excluded regions, a plurality of raised chambers (13,14,42,43) which contain a gas
or a fluid. The chambers (13,14) are much longer than wide, and in the
resulting composite film the chambers are arranged in sets in which they are
aligned; the sets are uniformly alternately distributed on the composite film
(10) so that the chambers (13,14) of different sets have alignments which
are set at an angle to each other.
Patent EP-1054400-A2 (EP)
Inventor: TSUTSUI KYOYA
IPC: G10L21/04
Filed: 2000-05-19
Abstract: To reproduce, from an original sound, a sound having a desired sufficiently
higher pitch than the original sound with not many operations and with no increase
of the manufacturing costs, there is provided a decoder for decoding a coded data
for reproduction, including a controller (139) to set a pitch of a reproduced signal
after decoded, and a partial decoder (133) to decode only a low frequency portion
of the coded data according to the pitch set by the controller.
Patent EP-1059758-A2 (EP)
Inventor: HIRANO AKIRA
IPC: H04L25/49
Filed: 2000-06-08
Abstract: An optical transmitter for realizing a high tolerance
with respect to the group velocity dispersion of the
optical fibers, a small receiver sensitivity degradation,
and an improved stability that is hardly affected by the
group velocity dispersion even in the case of network scale
expansion, is constructed by a light source section for
generating optical clock pulses synchronized with a signal
bit rate while maintaining a duty ratio of the optical
clock pulses constant, which is capable of variably setting
the duty ratio, and an encoding section for encoding the
optical clock pulses by using electric signals synchronized
with the optical clock pulses while setting a relative
optical phase difference between the optical clock pulses
in adjacent time-slots to be an odd integer multiple of π.
Patent EP-1072885-A2 (EP)
Inventor: RODE HANS-JUERGEN
IPC: A01D41/127
Filed: 2000-06-23
Abstract: The moisture level measuring device has a measuring capacitor (52) with spaced capacitor electrodes between which the crop is passed, connected in a resonance circuit (106) together with an inductance (104). The resonance circuit is supplied with an AC voltage signal of variable frequency, e.g. via a microcontroller (90), with detection of a resonance circuit parameter at different frequencies, for calculating the resonance frequency, used for addressing a stored table providing the corresponding crop moisture level. Also included are Independent claims for the following; (a) an agricultural machine; (b) a moisture level measuring method for an agricultural crop
Patent EP-1074836-A2 (EP)
Inventor: ABEDI JALEH AZMI
IPC: G01N30/86
Filed: 2000-08-01
Abstract: Methods for calculating Log P values for organic compounds are
disclosed. The methods allow identification of compounds in a library with
a desired Log P value. The method can be used to minimize the number of
compounds in a given combinatorial or lead generation library which need to
be further characterized and/or assayed. The Log P value is preferably
obtained while the purity of the compounds is being determined.
Preferably, the Log P value is correlated to the retention time on an HPLC
column, such that the retention time equals the Log P value.
Patent EP-1087640-A2 (EP)
Inventor: SCHOTTEN HENNO
IPC: H05B3/74
Filed: 2000-09-06
Abstract: The detection device has a resistance heating element (1) positioned below a hob cooking zone used simultaneously as a capacitive sensor, for detecting the presence of a cooking pan and/or the cooking pan size, by connecting the resistance heating element in an oscillator circuit and evaluating the oscillator resonance frequency.
Patent EP-1094111-A2 (EP)
Inventor: EIKMANNS BERNHARD
IPC: C12N1/21
Filed: 2000-10-05
Abstract: Isolated polynucleotide (I) from coryneform bacteria comprises a sequence at least 70% identical to the sequence that encodes a fully defined 610 amino acid protein (II) sequence (S2) given in the specification, sequences in plasmids pEK-pckA and pEK-pckB, a sequence encoding a polypeptide at least 70% identical to (II), their complements or a sequence of at least 15 consecutive bases from (I). Isolated polynucleotide (I) from coryneform bacteria comprises: (a) a sequence at least 70% identical to a sequence that encodes the fully defined 610 amino acid sequence (S2) given in the specification; (b) a sequence at least 70% identical to a sequence that encodes (S2) and is present in plasmids pEK-pckA and pEK -pckB; (c) a sequence encoding a polypeptide with an amino acid sequence at least 70% identical to (S2); (d) the complements of (a), (b) or (c); (e) a sequence of at least 15 consecutive bases from (a), (b), (c) or (d) Independent claims are also included for the following: (1) vectors (III) pEK-pckA and pEK-pckB (2) vector (IV) pK19mobsacB DELTA pck (deposited in Escherichia coli DH5 alpha  as DSM 13047); corynebacteria comprising (III) or (IV) or including a  DELTA pck deletion; and (3) fermentative production (P) of L-amino acids using a bacterium in which either (I) is downregulated or the activity of its encoded protein is reduced.
Patent EP-1134961-A2 (EP)
Inventor: FELLER JOERG
IPC: H01F27/42
Filed: 2000-12-16
Abstract: The transformer has a primary permanently connected to an a.c. source and a secondary for connection to a load. The primary is in series with a resistor with a parallel bridge with a switching element and the secondary is in series with a current sensing circuit forming a switch drive. The switch element is opened in idle mode when the secondary circuit is open and closed in loaded mode so the a.c. source voltage is the input voltage. The transformer has a primary coil (Le) permanently connected to an a.c. source (N) and a secondary coil (La) for connection to a load. The transformer primary is connected in series with a resistor (Rv) with a parallel bridge (12) with a switching element (S) and the secondary coil is connected in series with a current sensing circuit (I) forming a drive for the switch. The switch element is opened in idle mode when the secondary circuit is open and is closed in loaded mode so that the a.c. source voltage is applied as the input voltage.
Patent EP-1108665-A2 (EP)
Inventor: WATKISS CHRISTOPHER ROBIN
IPC: B65H3/48
Filed: 1996-03-18
Abstract: A suction device for feeding sheets (11) of material
comprises a housing connectable by a pipe to a vacuum device
(42) and having apertures over which the sheets pass and
through which a suction effect can be created. An
eccentrically mounted roller (46) imparts a distortion to the
attracted sheets. A single endless perforated belt (30)
passes over the apertured surface of the housing. The
distortion-imparting roller (46) acts on the inside of the
belt and is adjustable by knob (50) to vary the amount of
distortion.
Patent EP-1063396-A2 (EP)
Inventor: HIJIKATA TOSHIHIKO
IPC: B01J37/02
Filed: 2000-06-20
Abstract: A material having a thermal expansion co-efficient
approximately the same as that of a catalyst is adhered to
the entire outer side of an outer wall of a ceramic
honeycomb structure or a ceramic honeycomb catalyst carrier,
thereby providing a ceramic honeycomb structure, ceramic
honeycomb catalyst carrier, and ceramic honeycomb catalytic
converter using these. These structure, catalyst carrier,
and catalytic converter are capable of preventing cracks at
the perimeter of the ceramic honeycomb catalyst carrier, and
hence capable of preventing damage to the ceramic honeycomb
catalyst carrier in a sure manner.
Patent EP-1146845-A2 (EP)
Title: Preparations de lecithine comprimees
Inventor: ORTHOEFER FRANK T
IPC: A61K8/00
Filed: 2000-02-07
Abstract: La présente invention concerne des compositions se composant essentiellement de phospholipides, commercialement connues sous le nom de lécithine, selon lesquelles les phospholipides forment une masse solide, un phospholipide de cristal liquide, sans utiliser d'agents émulsifiants ou d'autres ingrédients traditionnellement utilisés comme vecteurs de phospholipides. L'invention concerne également des procédés permettant de fabriquer des compositions de phospholipides. Plus particulièrement, l'invention concerne une forme physique de phospholipides et son utilisation comme produit cosmétique topique pour la peau, comme supplément nutritif ou comme forme posologique à administrer par voie orale. Quelle que soit la forme exacte de la nouvelle composition de phospholipides, elle comprend une quantité de phospholipides égale à au moins 20 % environ en poids du produit total. La nouvelle composition de phospholipides apparaît sous forme d'un solide qui est produit en soumettant des phospholipides granulaires ou pulvérulents à des pressions élevées qui se traduisent par la formation de la composition de phospholipide solide.
Patent EP-1198590-A2 (EP)
Inventor: DENSHAM DANIEL HENRY
IPC: C12Q1/68
Filed: 2000-04-06
Abstract: L'invention concerne un procédé de séquençage de polynucléotide comprenant les étapes suivantes: (i) réaction entre un polynucléotide cible et une enzyme hélicase/primase (susceptible d'être immobilisée), dans des conditions appropriées à l'activité enzymatique; et détection de l'interaction entre l'enzyme et un nucléotide sur la cible, par mesure du rayonnement.
Patent EP-1181053-A2 (EP)
Inventor: STURMHOEFEL KNUT
IPC: A61P17/00
Filed: 2000-05-05
Abstract: Cette invention concerne des méthodes propres à favoriser des réponses immunitaires, selon lesquelles on administre des formes solubles de molécules de co-stimulation, telles que des molécules B7, pour accroître les réponses immunitaires à des antigènes tels que des cellules tumorales ou des agents infectieux. Les méthodes selon l'invention conviennent à titre tant prophylactique et thérapeutique pour l'immunisation de sujets.
Patent EP-1295126-A2 (EP)
Inventor: CHIEN DAVID Y
IPC: A61K35/14
Filed: 2000-07-25
Abstract: Immunoassays for detecting hepatitis C virus protein and immune complexes between hepatitis C virus protein and antibodies in biological samples, methods of screening blood products for hepatitis C virus, and kits employed therefor are provided.
Patent EP-1194171-A2 (EP)
Inventor: HILL-WEST JENNIFER L
IPC: A61K47/48
Filed: 2000-09-01
Abstract: L'invention concerne des hydrogels produisant du monoxyde d'azote (NO), de préférence photopolymérisables et biodégradables, pouvant libérer des quantités physiologiques de NO sur une durée prolongée, que l'on applique sur des sites ou à un patient nécessitant l'application de ce type de matériau pour le traitement de troubles comme la resténose, la thrombose, l'asthme, la cicatrisation, l'arthrite, la dysérection ou autres, dans lesquels le NO joue un rôle important. En règle générale, les hydrogels sont constitués de macromères, qui comprennent de préférence des zones biodégradables, et des groupes liés aux macromères sont libérés in situ, élevant ou modulant les niveaux de NO là où le traitement est requis. Les macromères peuvent former une homo ou hétéro-dispersion ou solution, polymérisée de manière à donner un matériau hydrogel qui, dans le dernier cas, peut être un réseau à semi-interpénétration ou à interpénétration. Les composés destinés à être libérés peuvent être physiquement emprisonnés, liés de façon covalente ou ionique au macromère, ou faire partie intégrante du matériau polymère. L'hydrogel peut être formé par réticulation ionique et/ou covalente. D'autres agents actifs (par exemple, thérapeutiques, prophylactiques ou diagnostiques) peuvent également être incorporés au matériau polymère.
Patent EP-1244427-A2 (EP)
Title: Pharmaceutical compositions for oral administration
Inventor: GUINEZ CHARLES
IPC: A61P7/02
Filed: 2000-12-27
Abstract: A method for oral administration of an active principle includes the steps of incorporating an active principle in multilamellar vesicles having a diameter of between 0.1 and 25 mum, and a lamellar liquid-crystal internal structure formed, from the center to the periphery of the vesicles, of a stack of concentric bilayers based on amphiphilic agents alternating with layers of water, aqueous solution or solution of a polar liquid, and orally administering a composition containing the active principle incorporated within the vesicles.
Patent EP-1174874-A2 (EP)
Inventor: BLOODWORTH BRYAN E
IPC: G11B5/09
Filed: 2001-07-19
Abstract: The present invention relates to a method of enhacing a preamplifier
read recovery in a hard disk drive system and comprises the steps of
determining whether the hard disk drive system is transitioning from a
non-read state (122) to a read state and initiating a non-read state to
a read state transition sequence (126) when a transition (124) from the
non-read state to the read state is determined. The transition sequence
is independent of a type of non-read state prior to the transitioning.
After the non-read state to read state transition sequence is complete
the read mode (104) is initiated. In addition, the invention comprises a
system for controlling a transition from a non-read state to a read
state associated with a preamplifier in a hard disk drive system. The
system comprises a detection circuit operable to detect a completion of
the non-read state and a non-read state to read state circuit operable
to execute a series of events to transition from the non-read state to
the read state, wherein the series of events is the same regardless of a
type of non-read state. 
Further, the system comprises a read state initiation circuit operable
to initiate the read state after the execution of the series of events.
Patent EP-1116622-A2 (EP)
Inventor: HAGANO HIROYUKI
IPC: B60K15/04
Filed: 2001-01-10
Abstract: A fuel tank fueling device (10) for feeding fuel through the fuel passage of an inlet
pipe into a tank main body is provided. The fueling device is easier to manipulate
when the fuel cap is opened and closed, and also has better fuel tank sealing properties
against the outside air. The fueling device includes a handle (43) provided on a casing
main body (20), operated to open and close the fuel passage; a sealing component (GS)
interposed between the casing main body and the seat surface of the fuel inlet pipe; a
spring (98) disposed so as to urge the sealing component against the seat surface; and a
cam mechanism (80,90) whereby the operating force of the handle in the closing direction is
converted via the spring into the sealing force of the sealing component pressing
against the seat surface.
Patent EP-1132551-A2 (EP)
Inventor: SCHULZE SIEVERT CHRISTOPH
IPC: E05B19/00
Filed: 2001-02-02
Abstract: The turning key for a lock device has a body (1) comprising at least two opposing main bodies (11), in which is at least one recess for at least one pin component (1,6) arranged in a core body (9) and a stator body (8) with a probe pin body. Between the first and second main bodies is an additional body, in which are two probe recesses for second pin components (5,6). The second pin components are at least partly arranged in the core body and in the stator body. The first and second main bodies and the additional body are round, oval, rectangular and/or quadratic in cross-section, and in them all a key profile is provided.