baber/WOPTO huggingface dataset:
Patent AT-E130293-T1 (AT)
Inventor: YANG DAVID
IPC: A61K31/135
Filed: 1991-09-27
Granted: 1995-12-15
Abstract: Applicants describe the synthesis of tamoxifen derivatives, most particularly halo, halo alkyl and hydroxy tamoxifen derivatives, wherein with the native tamoxifen molecule includes a substituted chemical group positioned on the aliphatic chain of the tamoxifen molecule. Particular halogenated tamoxifen derivatives of the invention include chloro, bromo, iodo and fluoro tamoxifen derivatives, and corresponding lower alkyl halogenated forms. The halogenated tamoxifen derivatives possess superior binding affinities for estrogen receptor rich tissues, such as uterine tissue and breast tissue, relative to unsubstituted native tamoxifen. In particular, the fluoro and bromo tamoxifen derivatives have potential use in imaging estrogen receptors by PET whereas the iodinated tamoxifens have potential use in imaging estrogen receptors by SPECT. The bromomethyl tamoxifen derivatives are demonstrated to bind estrogen receptors with the greatest enhancement of binding affinity over native tamoxifen. Rapid and efficient methods of preparing the tamoxifen derivatives having high specific activity (>6 ci/ mu mol) are also disclosed. Aliphatic chain substituted tamoxifen derivatives are shown to possess greater estrogen receptor binding affinity and more potent tumor cell inhibition than tamoxifen or tamoxifen derivatives substituted at other locations on the molecule (i.e., non-aliphatic chain substituted tamoxifen). The tamoxifen derivatives of the present invention may advantageously be used as anticancer therapeutic agents to halt estrogen-receptor positive tumors, such as those of breast and uterine tissue.
Patent AT-E133347-T1 (AT)
Inventor: SOBOCAN BORIS
IPC: B62M1/08
Filed: 1992-02-25
Granted: 1996-02-15
Abstract: A footboard of a skateboard is with respect to a respective reference plane which at riding straight (= x plane) is parallel to the riding path (= the ground), and at turning (= x'' plane) is with respect to the direction of riding slanted to one or the other side, is rhythmically swung around a longitudinal axis (O) of swinging lying in suspensions (4, 5) of the skateboard. The amplitude (A) and the frequency of swinging are mutually coordinated in a manner that swinging does not result in such meandering of the skateboard, which was felt inconvenient. To a socket shaft housing (8) of a suspension (4, 5) of the skateboard, said housing encasing a roller shaft (11), there is to each end thereof attached a gearing (9, 10), the gearings designed mirror-symmetrically. The gearing (9, 10) is composed of an essentially three-part housing assembly, which comprises a mounting casing (13), an upright intermediate wall (16) and a mounting cover (17), as well as of a train-type gearing composed of a toothed rack (19) as a driving constituent and a gear (25) bound to the roller shaft (11), as a driven constituent. In addition to the roller shaft (11) which passes through, two further, inner shafts (14, 15) constitute said gearing, the lastmentioned shafts each supporting two gears (20, 21; 23, 24), the first one (20) thereof mating the toothed rack (19) and the last one (24) mating the gear (25) driven. The second one (21) of the gears is indirectly connected to the respective shaft (14) by means of an overrunning clutch (22), and shaft (14) is by means of a suitably pre-stressed helical torsion-spring (28), which encompasses the shaft (14), rotationally-elastically bound to the stationary mounting casing (13) of the gearing.
Patent AT-E138484-T1 (AT)
Inventor: BLOME RAINER
IPC: G06K7/10
Filed: 1992-03-05
Granted: 1996-06-15
Abstract: A data carrier card (1) comprising a microprocessor chip (MC) with a data input interface (DI) and a data output interface (DD) which operate contactlessly. At the microprocessor element (MC), a micromotor element (R, B) is arranged which is used as reflector (R) or for shading a lightbeam (LP, LP') which is picked up by photosensors (P1, P2) so that the position of the micromotor element (R, B) represents a sequence of output data and supplies these to the interface (DD). The circuit is fed by a solar cell (SC) with an external light source (GL) which takes input data from a modulator (MOD) and sends them to the input interface (DI). <IMAGE>
Patent AT-E181771-T1 (AT)
Inventor: KRATZER MICHAEL DR
IPC: G01N35/10
Filed: 1992-05-08
Granted: 1999-07-15
Abstract: The invention relates to an apparatus for the automatic analysis of blood samples, comprising a test station (1) in which blood is removed from a supply vessel (5) and is passed through an aperture (19) in a part (18) retained in an aperture holder (3). At least one testing head (7) is provided, and this is supplied in successive order with supply vessels (5) containing blood from a first magazine device (8) and with aperture holders (3) from another magazine device (2; 2'). After at least one measurement on each aperture holder (3) the used aperture holder (3) and the used supply vessel (5) are removed from the testing head (7) and the testing head (7) is cleaned by a cleaning device (26, 27). <IMAGE>
Patent AT-E147169-T1 (AT)
Inventor: SUZUKI MASAAKI
IPC: G02F1/1341
Filed: 1992-10-06
Granted: 1997-01-15
Abstract: A liquid crystal injection method for a liquid crystal device including a region where image display pattern electrodes (112) are disposed within a cell surrounded by a seal (113) for enclosing a liquid crystal comprises injecting the liquid crystal while disposing a dummy pattern film (111) for promoting the liquid crystal injection at a part other than the region with the image display pattern electrodes (112) within the cell. <IMAGE>
Patent AT-E137741-T1 (AT)
Inventor: GOSTELI JACQUES
IPC: C07C237/06
Filed: 1992-10-07
Granted: 1996-05-15
Abstract: There are described compounds of the formula I <IMAGE> in which n is 1 or 2, R1 represents hydrogen or an amino protective group, R2 represents hydrogen or a carboxyl protective group and R3 represents 4-methyltriphenylmethyl, 4,4'-dimethyltriphenylmethyl or 4,4',4"-trimethyltriphenylmethyl, and reactive carboxylic acid derivatives of such compounds of the formula I which are suitable for coupling reactions and in which R2 represents hydrogen. The abovementioned compounds can be used as starting materials for the preparation of peptides. They are more suitable for this purpose than analogue compounds of the formula I in which R3 represents hydrogen or one of the previously used carbamoyl protective groups.
Patent AT-E219494-T1 (AT)
Inventor: ROHRMANN JUERGEN DR
IPC: C07B61/00
Filed: 1992-11-27
Granted: 2002-07-15
Abstract: The invention relates to a process for the preparation of a compound of the formula IV or IVa <IMAGE> in which R<1>-R<5> preferably denote hydrogen or alkyl, characterised in that a compound I <IMAGE> is reacted with a compound II <IMAGE> in which X<1> and X<2> preferably denote halogen, to give the corresponding indanones, which are converted into the compounds IV and IVa by reduction and dehydration. The compounds IV and IVa are important intermediates for the preparation of chiral metallocene complexes, which are suitable as catalyst components for olefin polymerization.
Patent AT-E143042-T1 (AT)
Inventor: MAEDA KAZUO
IPC: C08G59/14
Filed: 1992-12-23
Granted: 1996-10-15
Abstract: An epoxy resin composition comprising an epoxy resin, a hardener, a curing accelerator and a solvent, characterized in that said epoxy resin comprises as principal component an "epoxy resin a" which has a polydispersity coefficient, (Mw/Mn), lower than 2.5 and which is obtainable by reacting:   1. a polyglycidyl-etherified product (I), obtained by glycidyl-etherifying a polyfunctional phenolic compound, with 2. a difunctional epoxy resin (II), having the skeleton of at least one bisphenol compound selected from the group consisting of bisphenol A, bisphenol F and tetrabromobisphenol A, and with 3. at least one bisphenol compound (III), selected from the group consisting of bisphenol A, bisphenol F and tetrabromobisphenol A. ,
Patent AT-E124434-T1 (AT)
Inventor: SHIOBARA TOSHIO
IPC: C08G59/40
Filed: 1992-10-13
Granted: 1995-07-15
Abstract: Compositions comprising     a) an epoxidised novolak resin and b) from 0.1 to 100 parts by weight, based on 100 parts by weight of component a), of at least one compound of the formula I <IMAGE>  in which     X1 is chlorine or bromine,   X2 is chlorine, bromine or hydrogen,   Y is O or S,   R1 and R2, independently of one another, are C1-C4-alkyl, and R3 and R4 are identical or different substituted groups of the formula II <IMAGE> in which R1, R2, X1 and X2 are as defined above, or   R3 and R4 together form a group of the formula III <IMAGE> in which R1 and R2 are as defined above,   are highly suitable as flame inhibitors in epoxidised novolak systems.
Patent AT-E130532-T1 (AT)
Inventor: LIBERATI GUGLIELMO
IPC: B03C3/68
Filed: 1992-03-11
Granted: 1995-12-15
Abstract: A high-frequency, switching-type protected power supply, in particular for electrostatic precipitators, characterized by the fact of comprising a regulated power supply system (20) for providing direct voltage adjusted at a desired value and at a relatively low voltage; a high efficiency, high-frequency switching system (25) driving a step-up voltage transformer (27) until reaching substantially the desired operating voltage of the precipitator, the secondary circuit of which directly feeds, by means of a rectifier group (28), the electrostatic precipitator. The high-frequency switching system is controlled in its operation in response to abnormalities indicating an incipient discharge between the electrodes of the electrostatic precipitator to modify the operating conditions in order to avoid the formation of disruptive discharges with consequent possible damage to the entire power supply and/or electrostatic precipitator. <IMAGE>
Patent AT-E120609-T1 (AT)
Inventor: SCHEUFLER BERND
IPC: A01C15/00
Filed: 1992-01-17
Granted: 1995-04-15
Abstract: Currently used to determine the fertiliser-spreader settings necessary to give the required width and density of coverage with a particular fertiliser type are spreader tables or a mobile test bench. In order to provide a simple way of adjusting a fertiliser spreader to the optimum settings, even with fertilisers whose manufacturer is not known or whose properties have been altered by transport or storage, and without the need to spread many tons of fertiliser on test benches, at least one value specific to fertiliser is determined from a small sample and this value is allocated to settings determined for this fertiliser type in parallel large-scale testing. With a known type of fertiliser, the same fertiliser-specific value is determined in the same way and a definite setting determined by comparison. The settings determined in the large-scale testing are stored on a data-storage medium and the fertiliser-specific value is determined by a suitable measurement instrument from the small sample.
Patent AT-E190354-T1 (AT)
Inventor: WEICHSELBAUM RALPH R
IPC: A61K48/00
Filed: 1991-12-19
Granted: 2000-03-15
Abstract: This invention relates to genetic constructs which comprise an enhancer-promoter region which is responsive to radiation, and at least one structural gene whose expression is controlled by the enhancer-promoter. This invention also relates to methods of destroying, altering, or inactivating cells in target tissue by delivering the genetic constructs to the cells of the tissues and inducing expression of the structural gene or genes in the construct by exposing the tissues to ionizing radiation. This invention is useful for treating patients with cancer, clotting disorders, myocardial infarction, and other diseases for which target tissues can be identified and for which gene expression of the construct within the target tissues can alleviate the disease or disorder.
Patent AT-E169277-T1 (AT)
Inventor: RAWDON BLAINE K
IPC: B64C1/22
Filed: 1992-01-27
Granted: 1998-08-15
Abstract: A cargo ramp for an aircraft is constructed of two segments which are hinged together so that they may articulate about the ramp pitch axis. The first of the two segments is hinged to the cargo bed of the aircraft so that it may articulate relative to the cargo bed, again in pitch. The second segment abuts a surface to or from which cargo is to be transferred. The hinged ramp permits straight-across loading and unloading of cargo onto vehicles which have cargo bed heights different than the cargo bed height of the aircraft. In a modified embodiment, the ramp also compensates for a differential roll angle between the second ramp segment and the vehicle cargo bed. In this embodiment, the hinge connection between the two ramp segments permits relative motion of the second segment with respect to the first segment about its roll axis, as well as in pitch.
Patent AT-E133036-T1 (AT)
Inventor: KESTER JEFFREY JOHN
IPC: A23D9/007
Filed: 1992-05-15
Granted: 1996-02-15
Abstract: A reduced calorie fat composition comprising: (a) from about 50% to about 100% of polyol fatty acid polyesters consisting of a combination of liquid and solid polyol fatty acid polyesters, and from 0% to about 50% triglycerides. The liquid polyol fatty acid polyester having at least 50% saturated fatty acid radicals with not more than 14 carbon atoms, provides faster moisture transport than prior polyol fatty acid polyester fat compositions. As a result, foods cooked in the present compositions have good texture, crispness, mouthfeel, color, and taste with reduced calories.
Patent AT-E158121-T1 (AT)
Inventor: GRUENING HORST
IPC: H03K17/732
Filed: 1992-10-30
Granted: 1997-09-15
Abstract: PCT No. PCT/CH92/00222 Sec. 371 Date Apr. 28, 1993 Sec. 102(e) Date Apr. 28, 1993 PCT Filed Oct. 30, 1992 PCT Pub. No. WO93/09600 PCT Pub. Date May 5, 1993.In a circuit for hard driving a GTO, the conductor inductance (L1) and the internal inductance of the GTO (L2) form, together with a first capacitor (C1) situated in parallel via a switch (S), a series resonance circuit inside the gate circuit. In this connection, the chosen sizes of the first capacitor (C1) and of the first inductance (L1) are such that, if the first capacitor (C1) discharges via the two inductances (L1, L2), the gate current originating from the first capacitor (C1) exceeds half the value of a GTO anode current to be turned off within less than 5  mu s in the first quarter cycle of the series oscillatory circuit. Moreover, first means are provided which uncouple the first capacitor (C1) from the generation of the gate current after the first quarter cycle of the resonance circuit and allows the gate current to decay slowly in such a way that, at any time, it is greater than the tail current of the GTO. Finally, second means are provided in the form of a recharging circuit, which means are activated during the decay of the gate current and apply a holding current (VH) which is sufficient for blocking the gate (G) of the GTO after the decay of the gate current.
Patent AT-E187287-T1 (AT)
Inventor: KAUB WERNER
IPC: H02J13/00
Filed: 1993-03-03
Granted: 1999-12-15
Abstract: The invention relates to a power-consumption-controlling apparatus for controlling the operation of the load which is connected via it to the power-supply network. The apparatus functions as a ripple-control receiver and comprises elements (15, 17), which are connected to the network voltage (12), for identifying the control signal, which arrives via the power-supply network and is transmitted by the ripple-control system, as well as evaluating elements (20), which are connected to these identification elements, for evaluating the information content of the identified signal and for load control, based on this evaluation, by operating a switching element (RE1-RE6). The apparatus additionally functions as an autonomous time switch and comprises a clock as well as memory elements (26) into which commands can be programmed using a computer (28) which can be connected for the duration of the input, as well as evaluation elements (20), which are connected to these memory elements, for evaluating the information content of the memory elements (26) and for load control on the basis of this evaluation, by operating a switching element (RE1-RE6). <IMAGE>
Patent AT-E132303-T1 (AT)
Inventor: WIESINGER JOHANNES PROF DR-ING
IPC: H01T1/10
Filed: 1993-10-27
Granted: 1996-01-15
Abstract: A spark gap arrangement capable of handling lightning includes a first spark gap with a relatively high-resistance insulating layer having a relatively short spark-over path, and at least one second spark gap which, compared to the first spark gap, has a relatively low-resistance insulating layer with a relatively long spark-over path, the second spark gap being electrically connected in series to the first spark gap.
Patent AT-E134749-T1 (AT)
Inventor: NELANDER AKE
IPC: B60T11/08
Filed: 1993-11-05
Granted: 1996-03-15
Abstract: A brake lever for an S-cam brake has a worm wheel (3) engaging the S-cam shaft and a worm screw (4) meshing therewith. A clutch wheel (6) on the worm screw forms a clutch (8) therewith under the bias of a compression spring (9). A control movement is transmitted from an external reference point to the clutch wheel via a pinion (15), a carrier wheel (16) and a control screw (18), the common axis of these three parts being perpendicular to the worm screw, wherein the control screw meshes with the clutch wheel. The carrier wheel can be turned relative to the pinion an angular distance corresponding to the desired slack and is biassed to one end position by a torsion spring (17), which is also used to engage a one-way clutch (19) between the carrier wheel and the control screw. <IMAGE>
Patent AT-E166076-T1 (AT)
Inventor: RENZI FIORENZO
IPC: C08F2/44
Filed: 1993-10-27
Granted: 1998-05-15
Abstract: A polymerizable liquid composition includes   a polymerizable poly(allyl carbonate) of an aliphatic or cyclo-aliphatic polyol; an organic peroxide generator of free radicals selected from the group of perketals, and possibly   an organic dye and/or an organic photochromic compound.   The compositions can be transformed, by bulk polymerization, into an organic glass which is colourless, or coloured or photochromic, having good optical and mechanical characteristics. <IMAGE>
Patent AT-E149463-T1 (AT)
Inventor: SPANGLER MICHAEL L
IPC: B65G15/30
Filed: 1993-04-22
Granted: 1997-03-15
Abstract: A modular plastic conveyor belt assembled from a plurality of plastic modules (12), each module (12) having interfitting link ends (14,16,18) on opposite sides thereof, and all link ends (14,16,18) having pivot rod holes (20) to accommodate a pivot rod (22), wherein each module (12) is arranged so that the link ends (16,18) on one side of the module (12) are of two different widths, namely wide link ends (18) and narrow link ends (16), at least some of the narrow link ends (16) being positioned between the wide link ends (18), the wide link ends (18) serving as drive links for accommodating teeth of a drive sprocket, and the link ends (14) on the other side of the module (12) are of a single width. <IMAGE>
Patent AT-E144241-T1 (AT)
Inventor: RAMACHANDRAN RAMAKRISHNAN
IPC: B01D53/04
Filed: 1993-05-26
Granted: 1996-11-15
Abstract: A gaseous alkene is separated from a gaseous alkane by pressure swing adsorption alone or in combination with distillation wherein the alkene is preferentially adsorbed onto a bed of 4A zeolite at a temperature of at least about 50 DEG C and preferably in the range of 50 to 200 DEG C. Typically, the alkane is propane and the alkene propylene; alternatively, the alkane may be ethane, and the alkene ethylene. <IMAGE>
Patent AT-E188846-T1 (AT)
Inventor: WINTERSON WARREN D
IPC: A23F3/22
Filed: 1993-10-27
Granted: 2000-02-15
Abstract: A process for reordering tobacco, which results in no significant decrease in equilibrium tobacco CV or significant tobacco degradation, is provided. Tobacco to be reordered is contacted with an air stream having a relative humidity near the equilibrium conditions of the tobacco. As the ov content of the tobacco increases, the relative humidity of the air stream contacting the tobacco is increased to affect reordering of the tobacco. Also provided is a process for drying tobacco, which results in no significant change in equilibrium tobacco CV or significant tobacco degradation. Tobacco to be dried is contacted with an air stream having a relative humidity near or below the equilibrium conditions of the tobacco. As the OV content of the tobacco decreases, the relative humidity of the air stream contacting the tobacco is decreased to affect drying of the tobacco. It has been found that tobacco can be reordered or dried successfully in a continuous manner using a self-stacking spiral conveyor. <IMAGE>
Patent AT-E182770-T1 (AT)
Inventor: FRANCESCHI FRANCOIS
IPC: A61F2/16
Filed: 1993-04-09
Granted: 1999-08-15
Abstract: The invention relates to an intraocular implant for the capsular sac.   It comprises an optical part (12) and two securing loops (14, 16). Each loop (14, 16) comprises a first connection end (a) for connection to the optical part and a free end (b), the said connection ends (a) being substantially diametrically opposed, each loop comprising, between the said connection end (a) and the free end (b), an intermediate zone (c) exhibiting a greater width (w) in a plane coinciding substantially with the plane of the optical part, and the said connection end and the said free end likewise exhibiting a greater width (w) than the rest of the loop, as a result of which the said ends and the said intermediate zone exhibit a bending inertia in the plane of the optical part which is greater than that of the rest of each loop (d, e). <IMAGE>
Patent AT-E173186-T1 (AT)
Inventor: LEHTONEN PENTTI
IPC: B05D1/10
Filed: 1993-02-05
Granted: 1998-11-15
Abstract: Method of a coating a roll in a paper machine with powder of thermoplastic speciality plastic and metal, ceramic or cermet particles. The coating is carried out by spraying by using hypersonic plasma with a velocity of about 2000 m/s or more. <IMAGE>
Patent AT-E237613-T1 (AT)
Inventor: MANSOUR TAREK
IPC: C07D473/16
Filed: 1992-12-21
Granted: 2003-05-15
Abstract: Disclosed are processes for preparing compounds of formula (I) and pharmaceutically acceptable salts or esters thereof, wherein R2 is a purine or pyrimidine base or an analogue or derivative thereof; and Z is S, S = O or SO2. The invention also relates to intermediates of use in the preparation of these compounds.
Patent AT-E152915-T1 (AT)
Inventor: CHADA SUNIL
IPC: C12N15/09
Filed: 1992-11-30
Granted: 1997-05-15
Abstract: The present invention provides a method of destroying selected tumor cells comprising administering to a warm-blooded animal a vector construct which directs the expression of at least one immunogenic, non-tumorigenic form of an altered cellular component normally associated with the selected tumor cells. Also provided are vector constructs which direct the expression of altered cellular components. Representative altered cellular components include ras*, p53*, Rb*, alter protein encoded by the Wilms' tumor gene, ubiquitin*, mucin*, DCC, APC, MCC, neu, an altered receptor, and bcr/abl. Also provided are recombinant viruses carrying a vector construct, target cells infected with the recombinant virus, and pharmaceutical compositions comprising the recombinant virus and a pharmaceutically acceptable carrier or diluent.
Patent AT-E179774-T1 (AT)
Inventor: SCHOEN SIEGFRIED JOACHIM
IPC: E06B9/262
Filed: 1993-02-15
Granted: 1999-05-15
Abstract: PCT No. PCT/NL93/00033 Sec. 371 Date Mar. 29, 1994 Sec. 102(e) Date Mar. 29, 1994 PCT Filed Feb. 15, 1993 PCT Pub. No. WO93/16265 PCT Pub. Date Aug. 19, 1993.A tensioning, releasable mounting device (9) for a window covering structure mountable in a window recess (R) and including spaced apart beams (3, 4) supporting one or more tensioned cords (2) supporting and guiding a covering panel (1). The mounting device is mounted on each end of at least one beam, and is moveable between an active position, in which each cord (2) is tensioned, and a second position in which each cord (2) is slackened, so that the window covering is easily removed from the window recess.