baber/WOPTO huggingface dataset:
Patent EA-015426-B1 (EA)
Title: Process for preparing n-alkylnaltrexone halides
Inventor: DLUBALA ALAIN
IPC: C07D498/08
Filed: 2007-09-19
Abstract: The invention relates to a novel process for preparing N-methylnaltrexone bromide, comprising at least the steps consisting in: (i) reacting N-methylnaltrexone methylsulphate in an aqueous solution with an alkaline agent chosen from the group consisting of sodium carbonate, potassium carbonate, calcium carbonate, magnesium carbonate, caesium carbonate and strontium carbonate, and mixtures thereof, for a pH of the aqueous reaction medium of between 7 and 10, and then in (ii) reacting the product thus obtained with hydrobromic acid which is added for a pH of the aqueous reaction medium of between 0.5 and 5, and thus obtaining N-methylnaltrexone bromide.
Patent EA-032106-B1 (EA)
Title: Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Inventor: JACKSON SIMON MARK
IPC: A61K39/395
Filed: 2008-08-22
Abstract: Antigen binding proteins and monoclonal antibodies specifically binding with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Pharmaceutical compositions for treating or preventing a condition associated with elevated serum cholesterol levels in a subject are described. Nucleic acids encoding said antigen binding proteins and monoclonal antibodies, and recombinant expression vectors and host cells comprising the same are described. Methods of making antigen binding proteins and monoclonal antibodies and the use thereof in treating or preventing a condition associated with elevated serum cholesterol levels in a subject are also described.
Patent EA-018065-B1 (EA)
Title: Pyridines and pyrazines as pi3k inhibitors (phosphatidylinositol 3-kinase)
Inventor: BRUCE IAN
IPC: A61K31/4427
Filed: 2009-03-17
Abstract: The present invention concerns a compound of formula (I)or a salt, suitably a pharmaceutically acceptable salt, or solvate thereof, wherein the groups R, R, Ar', A and Y are defined in the description, to compositions and use of the compounds in the treatment of inflammatory and allergic pathologic conditions.
Patent EA-023626-B1 (EA)
Title: Process for the production of substitute natural gas
Inventor: EASTLAND PHILIP HENRY DONALD
IPC: C10L3/08
Filed: 2011-06-27
Abstract: The invention provides a process for the production of substitute natural gas comprising the following steps: providing a feed gas to a first and/or second and/or subsequent bulk methanator; subjecting that feed gas to methanation in the presence of a suitable catalyst; removing an at least partially reacted stream from the first bulk methanator and supplying it to the second and/or subsequent bulk methanator where it is subjected to further methanation; passing a product stream from the final bulk methanator to a trim methanator train where it is subjected to further methanation; removing a recycle stream downstream of the first, second or subsequent bulk methanator, and, in any order, passing it through a compressor, subjecting it to cooling and then supplying to a trim and/or recycle methanator for further methanation before being recycled to the first and/or second and/or subsequent methanator.
Patent EA-023823-B1 (EA)
Title: Method of producing coated food products
Inventor: PICKFORD KEITH
IPC: A23L13/00
Filed: 2012-01-18
Abstract: A method of producing a frozen, microwaveable, coated food product, said method comprising the steps of providing a portion of a solid or solidified substrate; coating the portion with an aqueous precoating liquid to form a precoated portion; applying a coating of bonding crumb to the precoated portion to form a crumb coated portion; applying a batter to the crumb coated portion to form a batter coated portion; applying a coating of coating crumb to the batter coated portion to form a breaded portion; frying the breaded portion by contacting said breaded portion for at least 100 seconds with hot oil having a temperature of at least 150°C, thereby producing a fried coated portion having a core temperature in excess of 70°C; and freezing the fried coated portion by introducing said fried portion into a freezer; wherein the core temperature of the fried coated portion is not less than 50°C, preferably not less than 60°C when said fried portion is introduced into the freezer and wherein said core temperature is reduced to less than -15°C, using cryogenic freezing.
Patent EA-024583-B1 (EA)
Title: Downhole setting tool (variants) and method of setting a liner hanger in a wellbore using such tool
Inventor: WATSON BROCK
IPC: E21B33/12
Filed: 2012-01-25
Abstract: A downhole setting tool is provided, comprising a tool housing and a hollow mandrel, the mandrel being situated in the housing. The tool further comprises a piston situated between the mandrel and the tool housing and a collar situated between the mandrel and the tool housing, wherein the tool housing, the mandrel, the piston and the collar define an annulus. The tool further comprises a first valve, wherein in a closed position the first valve blocks a path of fluid communication between the interior of the mandrel and the annulus.
Patent EA-032389-B1 (EA)
Title: Recombinant poxviral vectors encoding and expressing rabies virus g glycoprotein and oxl polypeptide, and vaccines made therefrom used in a method of vaccinating animals against rabies
Inventor: MEBATSION TESHOME
IPC: A61K39/12
Filed: 2013-02-14
Abstract: The invention relates to recombinant vectors encoding a Rabies G polypeptide and an OXL polypeptide which functions as a genetic adjuvant, for example, relates to poxviral vectors. The claimed vectors are used in a vaccine composition against animals rabies, in particular, in a canine. The invention relates to rabies vaccines made from the claimed vectors and to a method of vaccinating animals comprising administering the claimed vaccine.
Patent EA-029698-B1 (EA)
Title: Porcine circovirus type-2 (pcv2) subunit vaccine
Inventor: KUO TSUN-YUNG
IPC: C07K14/01
Filed: 2012-12-05
Abstract: The present invention relates to a porcine circovirus type-2 (PCV2) subunit vaccine, in particular to a porcine circovirus type-2 (PCV2) immunogenic composition, comprising an antigenic peptide, and also to a method for manufacturing the antigenic peptide encoded by the PCV2 ORF2. The antigenic peptide is selected from a non-arginine-rich peptide and a recombinant fusion protein.
Patent EA-030282-B1 (EA)
Title: Fermentation method
Inventor: MIHALCEA CHRISTOPHE
IPC: C12P7/40
Filed: 2013-03-28
Abstract: The present invention relates generally to methods for increasing the efficiency of microbial growth and production of products, such as alcohols and acids by microbial fermentation of substrates containing carbon monoxide. More particularly the invention relates to the provision of an alternative sulphur source to a liquid nutrient medium, such that sulphur is available to one or more microorganisms of the fermentation.
Patent EA-025599-B1 (EA)
Title: Concentrated lamellar liquid personal cleansing composition
Inventor: PALLA-VENKATA CHANDRA SEKHAR
IPC: A61K8/36
Filed: 2013-11-18
Abstract: The present invention relates to concentrated lamellar liquid personal cleansing compositions comprising: a) about 15 to 40% by wt. of synthetic anionic surfactant(s); b) about 5 to 30% by wt. of co-surfactant(s) selected from the group of amphoteric or nonionic surfactants or blends thereof; c) about 5 to 15% by wt. of C-Clinear alkyl fatty acid(s); d) wherein the synthetic anionic surfactant(s):co-surfactant(s) ratio is about 0.5 to 3; and e) wherein the synthetic anionic surfactant(s) and co- surfactant(s) to C-Clinear alkyl fatty acid(s) ratio is about 2 to 6. The proposed compositions provide better in-use sensory properties such as creamy appearing lather and improved skin feel, increasing the amount of lather and the speed to lather, and are stabilized against freezing/thawing.
Patent EA-029751-B1 (EA)
Title: Prolonged delivery of certain fragrance components from personal care compositions
Inventor: HARICHIAN BIJAN
IPC: A61Q13/00
Filed: 2014-03-10
Abstract: A personal care composition is provided having a highly volatile fragrance which incorporates alpha-pinene, beta-pinene, hexyl acetate, limonene, (+)-citronellal, dihydromyrcenol, alpha-citronellol, beta-citronellol, genaniol, lilial or combinations thereof in conjunction with tricyclodecane amide. The tricyclodecane amide functions to prevent fast volatilization of the highly volatile fragrance components when the personal care composition is applied to skin or hair of the human body.
Patent EA-027811-B1 (EA)
Title: N-(2,3-DIHYDRO-1H-PYRROLO[2,3-b]PYRIDIN-5-YL)-4-QUINAZOLINAMINE AND N-(2,3-DIHYDRO-1H-INDOL-5-YL)-4-QUINAZOLINAMINE DERIVATIVES AS PERK INHIBITORS
Inventor: STANSFIELD IAN
IPC: C07D413/14
Filed: 2014-03-31
Abstract: The present invention relates to N-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-4-quinazolinamine and N-(2,3-dihydro-1H-indol-5-yl)-4-quinazolinamine derivatives of Formula (I)wherein R, R, R, R, R, Rand A have the meaning defined in the claims. The compounds according to the present invention are useful as inhibitors of PERK. The present invention further relates to processes for preparing such compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
Patent EA-031635-B1 (EA)
Title: Treatment of produced water for supercritical dense phase fluid generation and injection into geological formations for the purpose of hydrocarbon production
Inventor: WEIMER LANNY DALE
IPC: E21B43/24
Filed: 2014-09-12
Abstract: Water, for example produced water, is treated to make it more suitable for use in an oil field recovery process. In the oil filed recovery process, the treated water is pressurized and heated to supercritical conditions in a steam generator, preferably a Once Through Steam Generator (OTSG), to result in a supercritical dense phase fluid, which is then injected into oil bearing formations for the purpose of enhanced oil production. The treatment includes softening and decarbonation. The water is preferably acidified before decarbonation. There may be a step of sulfate removal. Softening may be by ion exchange or membrane separation. Sulfate may be removed by ion exchange.
Patent EA-033342-B1 (EA)
Title: Pyrrolidine carboxamido derivatives and methods for preparing and using the same
Inventor: CHOI GILDON
IPC: C07D207/04
Filed: 2016-07-08
Abstract: Pyrrolidine carboxamido derivatives of formula 1optical isomers thereof, and salts thereof that are able to prevent, improve, and/or treat inflammatory conditions, including inflammatory bowel disease, and methods for preparing and using the same are provided.
Patent EA-035488-B1 (EA)
Title: Method for obtaining electrodes from alloys based on nickel aluminide
Inventor: LEVASHOV EVGENY ALEKSANDROVICH
IPC: B82Y30/00
Filed: 2016-07-19
Abstract: The invention relates to obtaining cast electrodes from high alloys based on nickel aluminide and may be used in additive 3D technologies in order to obtain geometrically complicated articles. The method includes obtainment of the semi-finished product through the centrifugal SHS casting with using the reaction mixture containing, wt.%: nickel oxide 47.0-49.1, aluminum 28.6-32.4, alloying additive 13.1-17.9, functional additive 6.5-7.0; a two-stage remelt of the semi-finished with obtaining the refined degassed ingot during the first stage and the electrode from the nanomodified alloy during the second stage, wherein during the said second stage some amount of the master alloy that consists of pressed aluminum and nanopowder mixture with a specific surface area of 5-30 m/g and lump aluminum is introduced into the melt before pouring the latter into the crystallizer to ensure the nanopowder content of 0.5-7 vol.% in the melt; with its further cooling down to the room temperature and extraction from the crystallizer. The invention is directed to the development of the integrated technology of electrodes made of alloys based on nickel aluminide.
Patent EA-034761-B1 (EA)
Title: Metering mechanism for a pump, methods for locking and unlocking such a mechanism
Inventor: LAATIAOUI NAJIB
IPC: F04B13/02
Filed: 2017-04-06
Abstract: The invention relates to a metering mechanism (7) comprising a body (70) mounted in a sleeve (77) covering it by the top and in an adjustment nut (71) covering it by the bottom, said adjustment nut being able to engage by screw connection with said sleeve, said screw connection then causing rotation of the adjustment nut with respect to the body of the metering mechanism, said body being extended by a valve seat (75) that can be closed by a valve (76) and that is able to receive a plunger (8) of which the reciprocating motion permits intake at the valve (76), the travel of the plunger depending on the screw position between the adjustment nut and the sleeve, characterized in that the metering mechanism further comprises means (M) to lock the rotation between the adjustment nut (71) and the body of the metering mechanism (70) so as to prevent the adjustment nut being screwed or unscrewed on the sleeve. The invention also relates to a method for locking and unlocking such a mechanism, and to a proportional metering pump incorporating such a mechanism.
Patent EA-038876-B1 (EA)
Title: Steel-pipe threaded joint
Inventor: SUGINO MASAAKI
Filed: 2018-10-02
Abstract: A threaded connection for a steel pipe is provided that improves its internal-pressure sealability while maintaining the high external-pressure sealability of a threaded connection having a nose used in a steel pipe with large diameter and large wall thickness. In a threaded connection for connecting steel pipe bodies each having an outer diameter equal to or larger than 7 inches (178 mm) and a wall thickness equal to or larger than 0.7 inches (18 mm), expression (1) in the description is satisfied and tB/tL>1.4, where , mm, is the clearance between the outer surface of the pin and the inner surface of the box upon make-up as measured at the borderline between the pin taper surface and the pin round surface, D, inch, is the outer diameter of the steel pipe body, t, inch, is the wall thickness of the steel pipe body, L, mm, is the distance between a pivot point, which is a position, in the region of contact between the pin sealing surface and the box sealing surface, which is closest to the tip of the pin, and the tip of the pin upon make-up as measured along the pipe-axis direction, tL, mm, is the wall thickness of the pin as measured at the pivot point, and tB, mm, is the wall thickness of the box as measured at the pivot point.
Patent ES-2173031-B1 (ES)
Title: Procedimiento de envasado de toallas y similares y toalla con preservativo o similiares envasada con el mismo.
Inventor: SOBREVIAS MAS FRANCISCO
IPC: B65D71/06
Filed: 2000-07-28
Granted: 2003-11-01
Abstract: Procedimiento de envasado de toallas y similares y toalla con preservativo o similares envasada con el mismo. El procedimiento comprende el plegado y/o arrollado de una toallita para conseguir una forma sensiblemente paralelepipédica recta, procediendo a continuación a la colocación de la misma en el interior de una envolvente de paredes rectangulares que determinan una estructura paralelepipédica recta con aristas vivas y cantos marcados, para su expendición por una máquina de venta automática.
Patent ES-2178957-B1 (ES)
Title: Nuevas aplicaciones de membranas asfalticas en reforestacion, silvicultura y agricultura en general.
Inventor: DEL RIO DOMINGUEZ MANUEL
IPC: A01G17/00
Filed: 2001-02-05
Granted: 2003-12-16
Abstract: Nuevas aplicaciones de membranas asfálticas en reforestación, silvicultura y agricultura en general. Dichas aplicaciones están destinadas al tratamiento y preparación del terreno destinado a realizar una plantación, para lo cual se extienden dichas membranas sobre el suelo previamente preparado, se perforan unos orificios en las mismas a través de los cuales se plantan los plantones o plántulas y se dejan crecer de forma natural, alcanzando un desarrollo mucho mayor que el que se alcanzaría en las mismas condiciones, en una zona carente de dichas membranas. La invención es particularmente útil en reforestación, silvicultura y agricultura en general.
Patent ES-2199690-B1 (ES)
Title: Perfeccionamientos introducidos en equipos electronicos de tomas multiples con transformador compensador para regulacion de tension alterna mediante conmutacion rapida dura con tension limitada carga mixta y bobina cortocircuitadora.
Inventor: CAMPO RODRIGUEZ JUAN CARLOS
IPC: G05F1/20
Filed: 2002-08-02
Granted: 2005-06-01
Abstract: Perfeccionamientos introducidos en equipos electrónicos de tomas múltiples con transformador compensador para regulación de tensión alterna mediante conmutación rápida dura con tensión limitada, carga mixta y bobina cortocircuitadora. La invención refiere a estabilizadores rápidos de tensión alterna con múltiples tomas y con transformador compensador para reducir en la red eléctrica perturbaciones lentas y perturbaciones rápidas. La reducción conseguible en las rápidas aumenta con la frecuencia de conmutación. Para aplicarlos con seguridad en elevadas potencias y frecuencias, la conmutación de los semiconductores en los cambios de toma debe eliminar solicitaciones extremas de tensión, corriente y potencia. La técnica existente no cubre adecuadamente este aspecto. Se reivindican mejoras conseguidas mediante un devanado auxiliar y una bobina cortocircuitadora que permiten, junto con unos procedimientos de conmutación adecuados, limitar los esfuerzos eléctricos y regular rápidamente la tensiónde salida sin introducir caídas de tensión adicionales, todo ello en diversas configuraciones del circuito principal.
Patent ES-2245146-B1 (ES)
Title: Persiana de formas en superficies superpuestas y deslizantes.
Inventor: SALUTREGUI MOURE EUGENIO
IPC: E06B9/04
Filed: 2002-08-23
Granted: 2007-06-16
Abstract: Persiana de formas en superficies superpuestas y deslizantes. Consiste en dibujar formas opacas en láminas trasparentes o traslúcidas (1) y (2) de modo que al superponerlas coincidan y se correspondan, pasando la luz por las zonas no dibujadas (3). Deslizando, horizontal o verticalmente, una lámina sobre otra, los dibujos o formas de una de ellas cubren las zonas trasparentes o traslúcidas (3) de la otra, tapando el paso de la luz. Sustituyendo las láminas por placas metálicas o de plástico, la luz pasa vaciando de material las zonas (3). Para mantenerla limpia se introduce en una cámara determinada por lunas de vidrio (4), convenientemente selladas. Se realiza su deslizamiento sobre gulas (7), girando un eje que porta, un piñón (5) y engrana con una cremallera (6) en la placa (1), eje que pasa por un taladro practicado en una de las lunas (4).
Patent ES-2264379-B1 (ES)
Title: Floculador-separador de fangos para el tratamiento fisico-quimico del agua.
Inventor: PALACIOS DONAQUE ENRIC
IPC: B01D63/00
Filed: 2005-05-26
Granted: 2008-03-01
Abstract: Floculador-separador de fangos para el tratamiento físico-químico del agua. El agua a tratar recibe en una cámara (1) con un mezclador rápido y de ella pasa a una segunda cámara de coagulación (3) y de ésta a una tercera cámara de floculación (4) donde se mezcla con unos reactivos coagulantes. A continuación entra en un separador (7) dotado de unas membranas filtrantes (5) donde se clarifica. En el separador (3) existen toberas (6) de aire que barren la superficie de dichas membranas filtrantes (5), unas toberas (8) de entrada de los flóculos procedentes de la coagulación-floculación y otras toberas (6) de salida de aire para distribución de los mismos por debajo de las membranas (5).
Patent ES-2288787-B1 (ES)
Title: Dispositivo de masaje.
Inventor: CANTO GARCIA ENRIQUE
IPC: A47C7/00
Filed: 2005-08-26
Granted: 2008-12-01
Abstract: Dispositivo de masaje. Se aplica en sillones de masaje y cuenta con un soporte de eje rotatorio y excéntrico (4) dotado de un orificio de acoplamiento (5) a dicho eje y unido mediante un punto de articulación (6) a un soporte de ruedas aplicadoras de masaje (1) que cuenta con una rueda superior (2) y con una rueda inferior (3). La rueda superior (2) conecta con el soporte de ruedas (1) a través de un brazo cervical (7), de manera que un extremo del brazo (7) articula con la rueda superior (2), en tanto que el otro extremo del brazo (7) presenta un punto de articulación (8) con el soporte de ruedas (1); disponiéndose además una biela (9) con un punto de articulación superior (10) conectado al brazo cervical (7) y con un punto de articulación inferior (11) conectado al referido soporte de eje (4); incluyéndose en el soporte de ruedas (1) un resalte con funciones de tope (12) al desplazamiento del brazo cervical (7).
Patent ES-2257217-B1 (ES)
Title: Equipo de manipulacion de cargas y contenedores.
Inventor: GRIJALBO GOICOECHEA JESUS
IPC: B66C23/04
Filed: 2005-11-21
Granted: 2007-05-16
Abstract: Equipo de manipulación de cargas y contenedores formado por dos grúas situadas una frente a la otra y unidas en sus extremos superiores por el dispositivo de rigidización formando un conjunto que permite el paso, entre las dos grúas y bajo el dispositivo de rigidización, de la carga o contenedor que es desplazada por el equipo de manera controlada por cualquiera de los dos laterales de la plataforma. Cada una de las grúas dispone de un mecanismo de giro horizontal y otro de elevación que actuando simultáneamente producen el desplazamiento del dispositivo de rigidización que las une, y con él la carga suspendida, paralelamente al plano horizontal de la plataforma y perpendicularmente a la misma. El equipo puede ser instalado en una plataforma fija, móvil o vehículo de transporte y permite la manipulación, carga, transporte y descarga, de cargas y contenedores.
Patent ES-2253130-B1 (ES)
Title: "dispositivo conmutador y modulador del ancho de pulso, procedimiento de limitacion de corriente en el mismo y convertidor que comprende dicho dispositivo".
Inventor: CAMACHO LOPEZ MANUEL
IPC: H02M3/315
Filed: 2005-11-22
Granted: 2007-07-01
Abstract: Dispositivo conmutador y modulador del ancho de pulso, procedimiento de limitación de corriente en el mismo y convertidor que comprende dicho dispositivo. El dispositivo de la invención está caracterizado porque el drenador o surtidor del citado transistor opuesto al surtidor o drenador conectado a la referencia de tensión se encuentra conectado a la citada entrada de sensado del citado controlador de modulación del ancho de pulso a través de un elemento multiplexor que recibe una señal de comando coordinada con la señal de activación del transistor, de manera tal que el elemento multiplexor transfiere la salida del drenador hacia la citada entrada de sensado de corriente cuando el citado transistor se encuentra en estado de saturación, no transmitiéndola cuando el transistor está en estado bloqueado.
Patent ES-2277780-B1 (ES)
Title: Conjunto enfriador de un sistema de aire acondicionado y procedimiento de enfriamiento.
Inventor: MEDRANO ALIJAS ANDRES
IPC: F24F5/00
Filed: 2005-12-01
Granted: 2008-06-16
Abstract: Conjunto enfriador de un sistema de aire acondicionado, consta de una torre-depósito (1) que tiene una parte superior (27) independizable del resto, al que se conecta un enfriador de agua (4) y un depósito (21) de tubos convertible en fancoil, interpuesto entre la torre y el condensador, contando el conjunto con unos medios de enfriamiento basado en el empleo de unas entradas de aire asociadas a unos extractores eléctrico-estáticos, y de unas sondas de entrada de agua fría a diferentes niveles dentro del depósito, estando todo el conjunto asociado con unos sensores de temperatura tanto dentro de la torre-depósito como en el exterior, permitiendo una enfriamiento del agua, con un menor consumo energético, menor ruido y sin peligro de infección de bacterias y gérmenes.