baber/WOPTO huggingface dataset:
Patent NZ-516888-A (NZ)
Title: Acyclic and cyclic amine derivatives
Inventor: MULLICAN MICHAEL
IPC: C07C211/29
Filed: 2000-07-27
Abstract: An acyclic or cyclic amine derivative or pharmaceutically acceptable salts thereof has the formula (I) wherein: X is -CH2CH2-, -CH=CH-, -C(OH)CH2-, -CH2C(OH)-, =C(F)CH2-, - C(F)=CH2-, -NHC(O)-, -P(O)(OH)CH2-, -CH2SO2-, -C(S)NR1-, - C(O)CH2CH(OH)-, -C(OH)CF2-, -C(O)CF2-, -CH(F)CH2-, - C(F)2CH2-, tetrazolyl or an epoxy group; A, B and R1 are independently E, optionally substituted alkyl, alkenyl or alkynyl, cycloalkyl or cycloalkenyl wherein 1 to 2 of the-CH2- groups in the alkyl, alkenyl, or alkynyl is optionally and independently replaced by -O-, - S(O)0-2-, =N-, -N= or -N(R3)- or B and R1 are independently hydrogen; E is an optionally substituted optionally saturated or aromatic monocyclic or bicyclic ring system, wherein each ring comprises 5 to 7 ring atoms independently selected from C, N, N(R3), O or S(O)0-2 and wherein no more than 4 ring atoms are selected from N, N(R3), O or S(O)0-2; J is H, methyl, ethyl or benzyl and K and K1 are independently optionally substituted alkyl, alkenyl or alkynyl, or cyclohexylmethyl, or J and K, taken together with the nitrogen and carbon atom to which they are respectively bound, form optionally substituted 5-7 membered heterocyclic ring, optionally containing up to 3 additional heteroatoms selected from N, N(R3), O, or S(O)0- 2; G, when present, is -S(O)-2-, -C(O)-, S(O)2-Y-, C(O)-Y-, - C(O)-C(O)-, or -C(O)-C(O)-Y-; Y is oxygen or N(R6); D is hydrogen or optionally substituted alkyl, alkenyl or alkynyl, cycloalkyl or cycloalkenyl optionally substituted with alkyl or alkenyl or alkynyl, alkyl-E, -alkenyl-E or alkynyl-E, or E; x is 0 or 1 and R3 and R6 are as defined in the specification; provided that when J is hydrogen or G is S(O)2, C(O)C(O), SO2-Y, C(O)-Y, or C(O)C(O)-Y and Y is O; then D is not hydrogen. The compounds are useful for stimulating neuronal regeneration or preventing neurodegeneration in a patient or in an ex vivo nerve cell.
Patent NZ-519621-A (NZ)
Title: Animal securing system
Inventor: FAGAN ROBIN CHRISTOPHER FELTRI
IPC: A01K11/00
Filed: 2002-06-14
Abstract: An animal sorting system whereby upon an animal passing an opened gate to an animal passageway an animal presence detector is triggered which in turn signals a gate position control assembly to reposition the gate to a closed position behind the animal.
Patent NZ-520701-A (NZ)
Title: Serum free cultivation of primate embryonic stem cells with fibroblast growth factor supplied seperately from fibroblast feeder layers
Inventor: THOMSON JAMES A
IPC: C12N5/07
Filed: 2001-03-02
Abstract: A method for culturing primate embryonic stem cells comprises culturing the primate embryonic stem cells in an in vitro culture containing amino acids, vitamins at least one transferring or transferring substitute and at least insulin or insulin substitute, the culture being essentially free of mammalian fetal serum and that contains exogenously supplied mammalian fibroblast growth factor that is supplied from a source other than just a fibroblast feeder layer.
Patent NZ-528543-A (NZ)
Title: A stable pharmaceutical composition of pravastatin and a carrier
Inventor: NAGAPRASAD VISHNUBHOTLA
IPC: A61K9/20
Filed: 2002-03-22
Abstract: A stable pharmaceutical composition suitable for oral administration comprises an effective amount of pravastatin and a carrier. The carrier comprises at least one water soluble diluent selected from compressible sugar, lactose, sucrose, sorbitol, mannitol, dextrates, dextrin, dextrose, maltodextrin and mixtures thereof or a water dispersible diluent selected from cellulose, cellulosic derivatives, starch, starch derivatives, clay, clay minerals and mixtures thereof, and sodium stearyl fumarate as a lubricant to impart a pH between 6.5 and 8.5 to an aqueous dispersion of the composition. Also described is a process for making the composition.
Patent NZ-529160-A (NZ)
Title: Oligonucleotide compositions and their use to induce differentiation of cells
Inventor: FILION MARIO C
IPC: A61P7/00
Filed: 2002-04-23
Abstract: A composition comprising a 3-OH, 5-OH, chemically unmodified, synthetic phosphodiester nucleotide sequence selected from a group of sequences, and a pharmaceutically acceptable carrier, wherein the composition is effective to induce differentiation of cells or increase differentiation of pluripotent cells.
Patent NZ-529902-A (NZ)
Title: Method of providing an essential oil extract of capsicum that retains the natural capsaicinoid to terpene ratio
Inventor: TORRES LORENZO
IPC: A61K36/81
Filed: 2001-08-31
Abstract: Methods of providing an essential oil extract of capsicum, and the extract itself, are provided. The extract contains capsaicinoid and terpene. Capsicum from which seeds and stems have preferably been removed is mixed, in powder form, with a solvent, particularly pentane, to dissolve at least some of the capsicum. During or after the mixing step, the liquid solution of capsicum in the solvent is brought to a temperature of less than or equal to 64 DEG C to significantly reduce the solvent content thereof and produce an essential oil extract that contains capsaicinoid and terpene, especially in the naturally occurring ratio thereof.
Patent NZ-532866-A (NZ)
Title: Jet injector with hand piece
Inventor: ROGATCHEV VICTOR T
IPC: A61M5/20
Filed: 2002-10-11
Abstract: The present invention relates to a jet injector system with a hand piece. The present invention generally comprises a power unit, a medicine unit, an energy unit, a supply bottle, and a hand piece. The hand piece and power unit may be separate components connected to each other by a high pressure hose, which gives the user more flexibility. A valve assembly having a ball lock assembly and a needle assembly controls the release of medication from the high pressure hose into the hand piece and out a nozzle into the subject
Patent NZ-532927-A (NZ)
Title: Amide substituted imidazopyridines and pharmaceuticals for inducing cytokine biosynthesis and treating viral and neoplastic diseases
Inventor: DELLARIA JOSEPH F
IPC: A61P17/00
Filed: 2002-06-07
Abstract: A compound of formula (I) is described wherein: X is alkylene or alkenylene; Y is -CO- or -CS-; Z is a bond or-O- or -S- R1 is aryl, heteroaryl, heterocyclyl, alkyl or alkenyl each which may be unsubstituted or substituted; R2 is selected from H, alkyl, alkenyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, alkyl-O-alkyl, alkyl-S-alkyl, alkyl-O-aryl, alkyl-S-aryl, alkyl-O-alkenyl, alkyl-S-alkenyl and alkyl or alkenyl substituted; R3 and R4 are selected from hydrogen, alkyl, alkenyl, halogen, alkoxy, amino, alkylamino, dialkylamino and alkylthio; R5 is H or C1-10 alkyl, or R5 can join with X to form a ring that contains one or two hetero atoms; or when R1 is alkyl, R5 and R1 can join to forma ring R6 is H or C1-10alkyl. A pharmaceutical composition comprising the compound is useful for inducing cytokine biosynthesis, in treating viral disease and for treating a neoplastic disease. Also described is a compound of formula (II) wherein: X is alkylene or alkenylene; R5 is H or C1-10 alkyl, or R5 can join with X to form a ring that contains one or two hetero atoms; and R2, R3, R4 and R6 are as defined above.
Patent NZ-535925-A (NZ)
Title: An isolated antibody that binds to a particular polypeptide
Inventor: FRANTZ GRETCHEN
IPC: A61K47/48
Filed: 2003-04-10
Abstract: Disclosed is an isolated antibody that binds to a polypeptide having at least 80% identity to the polypeptide shown in Figure 30 (SEQ ID NO:30).
Patent NZ-537583-A (NZ)
Title: Novel thiophene glycoside derivatives, methods for production thereof, medicaments comprising said compounds and use thereof
Inventor: GLOMBIK HEINER
Filed: 2003-06-27
Abstract: Thiophene glycoside derivatives of formula (I) and their physiologically-acceptable salts that are suitable as anti-diabetics, and methods for production thereof are disclosed, wherein the variables are as defined in the specification.
Patent NZ-537645-A (NZ)
Title: Methods and compositions for simultaneous saccharification and fermentation
Inventor: INGRAM LONNIE O
Filed: 2001-06-19
Abstract: Disclosed is a method for degrading an oligosaccharide comprising contacting an oligosaccharide with an isolated recombinant host cell, said host cell comprising: a first heterologous polynucleotide segment encoding a first endoglucanase having a first degrading activity, wherein said segment is under the transcriptional control of a surrogate promoter; a second heterologous polynucleotide segment encoding a second endoglucanase having a second degrading activity, wherein said segment is under the transcriptional control of a surrogate promoter; and a polynucleotide segment expressing an additional enzyme; wherein said first endoglucanase and said second endoglucanase are expressed so that said first and said second degrading activities are present in a ratio such that the degrading activities of said first and second endoglucanases are synergized and the oligosaccharide is degraded by the synergistic action of the endoglucanases, and wherein said first endoglucanase is encoded by celZ and said second endoglucanase is encoded by celY, and wherein celZ and celY are derived from Erwinia, thereby degrading an oligosaccharide.
Patent NZ-541832-A (NZ)
Title: A laser level
Inventor: WATTERS ROBERT D
IPC: G01C15/00
Filed: 2004-11-01
Abstract: A laser level is provided with an aperture 48 in the top of the level housing and a strap 18 engaged with the aperture for suspending the level so that the laser level light projects from the housing perpendicularly to the vertical direction.
Patent NZ-542595-A (NZ)
Title: Modulation of growth hormone receptor expression and insulin-like growth factor expression
Inventor: TACHAS GEORGE
IPC: C12Q1/68
Filed: 2004-02-27
Abstract: Disclosed is a compound comprising an oligonucleotide of from 12 to 50 nucleobases in length targeted to a nucleic acid molecule encoding growth hormone receptor, wherein said oligonucleotide is fully complementary to the nucleotide sequence within the coding region of SEQ ID NO: 4, as measured over the entirety of said oligonucleotide, wherein said oligonucleotide comprises at least one modified internucleoside linkage, modified nucleobase, or modified sugar, and wherein said oligonucleotide inhibits the expression of growth hormone receptor mRNA by greater than 45% when applied in vitro to MCF7 cells.
Patent NZ-546621-A (NZ)
Title: Humanized antibodies that recognize beta amyloid peptide
Inventor: BASI GURIQ
IPC: C07K16/00
Filed: 2001-12-06
Abstract: Provided is a kit comprising a humanized immunoglobulin, or antigen-binding fragment thereof, which specifically binds to beta amyloid peptide (A beta) with a binding affinity of at least 107 M-1, comprising (i) a light chain comprising at least one variable region complementarity determining region (CDR) from the 3D6 immunoglobulin light chain variable region sequence of a specified sequence, and a variable framework region from a human acceptor immunoglobulin light chain sequence, and (ii) a heavy chain comprising at least one variable region CDR from the 3D6 immunoglobulin heavy chain variable region sequence of another specified sequence, and a variable framework lo region from a human acceptor immunoglobulin heavy chain, provided that the humanized immunoglobulin, or antigen-binding fragment thereof, comprises; (a) at least one substitution of a canonical framework residue selected from the group consisting of L2, L48, L64, L71, H24, H26, H27, H29, H71, and H94 (Kabat numbering convention), (b) at least one substitution of an interchain packing framework residue selected from the group consisting of L36, L38, L44, L46, L87, L98, H37, H39, H45, H47, H9 1, H93, and HI03 (Kabat numbering convention), and (c) at least one substitution of a vernier zone framework residue selected from the group consisting of L4, L35, L47, L49, L66, L68, L69, H2, H28, H30, H48, H49, H67, H69 and H80 (Kabat numbering convention), or at least one substitution of a rare framework residue selected from the group consisting of L1, L15, L83, L85, H40 and H42 (Kabat numbering convention), wherein the substitution is with the corresponding amino acid residue from the mouse 3D6 light chain variable region sequence or the mouse 3D6 heavy chain variable region sequence, and wherein said kit further comprises instructions for use of the immunoglobulin or fragment thereof as a medicament. Further provided are other kits comprising specified variants of the sequences.
Patent NZ-552487-A (NZ)
Title: Drive circuits for dual stator winding load commutated inverter ( LCI ) electric machines
Inventor: LEWIS ERIC ANTHONY
Filed: 2007-01-08
Abstract: A drive circuit for interfacing an electrical machine having a stator to an AC network, the circuit comprising: first and second network rectifier/inverters connectable to the AC network in parallel; a first PWM rectifier/inverter connected to the first network rectifier/inverter through a first DC link; a second PWM rectifier/inverter connected to the second network rectifier/inverter though a second DC link; a first two-layer stator winding having a plurality of stator coils connected to the first PWM rectifier/inverter; and a second two-layer stator winding having a plurality of stator coils connected to the second PWM rectifier/inverter. The stator coils of the first stator winding and the stator coils of the second stator winding are interconnected such that, in use, the vector sum of voltages across the stator coils in the first stator winding is substantially equal to the vector sum of voltages across the stator coils in the second stator winding. This reduces the PWM frequency current harmonics flowing in the first and second stator windings.
Patent NZ-561740-A (NZ)
Title: Method for implementing required navigational performance procedures
Inventor: GERRITY DANIEL A
IPC: G06G7/70
Filed: 2006-03-10
Abstract: A computer-implemented method for designing an approach path for an aircraft approaching a particular runway is disclosed. The method includes: selecting a runway; gathering topographic data for an obstacle evaluation area for the selected runway; identifying all upwardly projecting obstacles in the obstacle evaluation area; laying out a preliminary approach path to the runway; calculating an obstacle clearance surface for the preliminary approach path comprising a first segment of the obstacle clearance surface that is calculated using a vertical error budget calculation, a momentary descent segment of the obstacle clearance surface that is calculated using a physical model of the aircraft performance, and a missed approach segment of the approach segment of the obstacle clearance surface that is calculated to define a first climb portion to a specified altitude and a level portion;adjusting the obstacle clearance surface such that none of the identified upwardly projecting obstacles intersects the obstacle clearance surface.
Patent NZ-562583-A (NZ)
Title: Method for distributing computing between server and client
Inventor: CHARLES JOHN FRANCIS
IPC: G06F13/00
Filed: 2006-03-16
Abstract: A method and system for use in running a display-based computer application is disclosed, the computer application comprising a plurality of application segments, where computing is distributed between a server and a client computer. The method comprises of providing a generic client engine to the client computer, the client engine comprising an application manager, one or more display managers, and one or more load managers. The method also comprises of providing a collection of individual application subset definition files, each relating to one of the application segments. On receipt of successive application subset definition files from the server, the client recursively transforms to provide the respective application segments.
Patent NZ-563355-A (NZ)
Title: Apparatus for pushing items relative to a surface
Inventor: DAVIDZON NORMAND
Filed: 2007-11-13
Abstract: An articulated pushing apparatus (10) that may be used to push items (12) from a conveyor surface (14) is disclosed. A rotational member (18) drives a pushing member so that in a first stroke the pushing member moves horizontally across the surface from a rest position to an extended position, and in a second stroke the pushing member returns to the rest position with an arcuate motion that clears items on the surface. A linkage (26) couples the rotational member to the pushing member and is arranged such that with continuous rotation of the rotational member the pushing member repeatedly cycles through the first and second strokes.
Patent NZ-566089-A (NZ)
Title: Frame for security door having a screen riveted in an open channel and ends of rivets received in a closed channel
Inventor: SHEEN AARON HARVEY
Filed: 2008-02-20
Abstract: A security screen mounted in a closure, particularly for use as a security door, and an extrusion for use in the closure are disclosed. The closure has a metal frame formed from the extrusion (16), with a security screen mounted within the frame. The extrusion has an open channel (24) formed from first and second parallel spaced walls (26, 28), and a closed channel (30) located on one side of the open channel. The screen is mounted in the open channel, and rivets (56) are passed through holes in the first and second walls and in the periphery of the screen. One end of the rivets is received in the closed channel. The closed and open channels are integrally formed.
Patent NZ-572900-A (NZ)
Title: Panel for construction with polystyrene core and fabric/granular layer cover adhered by polyurethane resin
Inventor: WATTS FRED
IPC: B32B7/04
Filed: 2007-12-20
Abstract: A panel is disclosed for use in construction having a polystyrene foam substrate, a polyester fabric on at least one face of the substrate bonded with a layer of polyurethane resin, wherein the polyester fabric and the polyurethane foam combine to form a bonded cover layer to form with the substrate a panel, and a granular material is applied to the polyester fabric. (62) Divided Out of 564715
Patent NZ-573460-A (NZ)
Title: Brain function monitoring and display system
Inventor: LILEY DAVID TIBOR JULIAN
IPC: A61B5/374
Filed: 2007-06-06
Abstract: A system for displaying the activity of a brain of a subject is disclosed. The system includes a plurality of electrodes for picking up EEG signals from the brain of the subject; digitising means for converting the EEG signals to a digitised EEG data signal and computing means. The computing means (i) segments EEG signal into either contiguous or overlapping segments comprised of a sequential number of samples of EEG signal; (ii) represents EEG segments as a fixed order autoregressive moving average (ARMA) signal representation with an autoregressive order between 8 and 13 and a moving average order between 5 and 11; (iii) rewrites in z-domain notation fixed order ARMA signal representation to obtain a z-domain representation; (iv) generates AR coefficient data and MA coefficient data for segments of EEG signal for fixed order ARMA signal representation; (v) determines the poles of z-domain representation for segments of EEG signal by substituting coefficient data for segments of EEG signal into z-domain representation; (vi) determines the sum of poles (zp ) for segments of EEG signal as either; (a) the sum of the number of poles determined in step (v); or (b) the first autoregressive AR coefficient of coefficient data for fixed order ARMA signal representation; (vii) determines the mean pole location for segments of EEG signal by dividing the sum of poles (zp ) by the number of poles; and (viii) determines an index value representing the activity of the brain for segments of EEG signal by applying a discriminating function to either the sum of the poles (zp) or the mean pole location for segments of EEG signal; and display means for displaying this index value.
Patent NZ-573985-A (NZ)
Title: Telecommunications module plug with rotating shutter and drip point
Inventor: SIMS DAVID JOHN
IPC: H01R13/447
Filed: 2010-03-22
Abstract: Disclosed is a telecommunications module (200) with improved protection and ease of disassembly for cleaning and maintenance. The module comprises: a casing (230), a signal conductor, and a rotating shutter (204). The casing has an internal cavity and an opening which passes into the cavity, the opening and cavity to receive a plug. The shutter is coupled to the casing and rotates between open and closed, where the front face of the shutter covers the opening when closed. The conductor is within the casing and connects to wiring and the plug to transmit signals. The casing is formed from releasably engageable components around the conductor and shutter. The casing has a drip point (212) to provide a location for the discharge of accumulated liquid.
Patent NZ-574265-A (NZ)
Title: N-(aminoheteroaryl)-1h-indole-2-carboxamide derivatives, preparation thereof and therapeutic use thereof
Inventor: DUBOIS LAURENT
IPC: C07D401/12
Filed: 2007-07-20
Abstract: Disclosed is an indole compound of formula (I) where the substituents are as disclosed in the description. Examples of compounds of formula (I) include: N- [6-Dimethylamino-4-(trifluoromethyl)pyridin-3-yl] -5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxamide; N-[6-Dimethylarnino-5-fluoropyridin-3-yl]-5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxamide and N-[6-(Acetylamino)pyridin-3-yl]-5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxamide. Also disclosed is a pharmaceutical composition or medicament comprising a compound of formula (I); the process for making a compound of formula (I) and the use of a compound of formula (I) in the manufacture of a medicament for treating pain, inflammation, urological disorders, gynaecological disorders, gastrointestinal disorders, respiratory disorders, psoriasis, pruritus, irritation of the skin, eyes or mucous membranes, herpes or shingles or to treat depression or diabetes.
Patent NZ-577237-A (NZ)
Title: Use of peo-pbo block copolymers in ophthalmic compositions
Inventor: KETELSON HOWARD ALLEN
IPC: C11D1/00
Filed: 2007-12-10
Abstract: Disclosed is an ophthalmic composition comprising an effective amount of at least one poly(oxyethylene)-poly(oxybutylene) block copolymer having a molecular weight in the range of 500 to 100,000 Daltons and an ophthalmically acceptable vehicle therefor. Also disclosed is a method of treating a contacts lens which comprises applying said composition to a lens.
Patent NZ-579980-A (NZ)
Title: Chair for a chair lift with foot rests aligned to the centre of the seat and attached to the safety bar
Inventor: SUTTER JOSEF
IPC: A47C7/50
Filed: 2009-09-28
Abstract: A foot rest (11) for each seating position (14) on a chair lift chair (1) is disclosed. The foot rest (11) is attached by a support bar (12) to a protective bar (2), which extends across the entire seat (1) and can be pivoted from an open position to a closed position. In the closed position of the protective bar (2) the supporting bar (12) extends down in the central region in front of each seating position (14) so that each has an associated central footrest (11).
Patent NZ-580967-A (NZ)
Title: Composition comprising a bile salt and an effervescent excipient component for transmucosal delivery of polypeptides
Inventor: DURFEE STEVE L
IPC: A61K38/095
Filed: 2008-05-01
Abstract: Disclosed is an oral transmucosal composition comprising: a) A therapeutically effective amount of a biologically active polypeptide; b) An effervescent component; and c) A bile salt. Further disclosed is the use of said compositions in the manufacture of oral transmucosal pharmaceutical compositions.