baber/WOPTO huggingface dataset:
Patent CA-3128747-A1 (CA)
Inventor: ARLINGHAUS PAUL R
IPC: E05B45/06
Filed: 2020-02-03
Abstract: An exemplary trim assembly comprises a housing assembly, a cam rotatably mounted to the housing assembly, a lift finger slidably mounted in the housing assembly such that the cam is operable to linearly drive the lift finger between a deactuated position and an actuated position, and a locking mechanism operable to selectively retain the lift finger in the deactuated position. The locking mechanism includes an interface member engaged with the lift finger such that movement of the lift finger moves the interface member between a home position and an offset position, a blocking member operable to selectively prevent movement of the interface member from the home position, and a driver configured to move the blocking member between a blocking position and an unblocking position to thereby lock and unlock the trim assembly.
Patent CA-3129519-A1 (CA)
Title: System and method for coordinating physician matching
Inventor: RICE ADAM
IPC: G16H40/20
Filed: 2020-02-06
Abstract: A system and method for coordinating physician matching for a user. The system including an interface configured to receive preference data related to the user. The system further includes a physician recommendation module being applied to the preference data and corresponding physician data. The physician recommendation module can track the preference data received by the interface, compare the preference data to the corresponding physician data, and recommend a list of physicians to the user when the physician data is above a threshold value. A display coupled to the recommendation module and configured to display the list of physicians to the user.
Patent CA-3131116-A1 (CA)
Inventor: LAI MING-TAIN
IPC: C12P7/02
Filed: 2020-02-21
Abstract: A new process to synthesis of compound OBI-3424 R-form and S-form products is provided. The "R-form" compound OBI-3423 was first synthesized with 48% overall yield from compound OBI-3424-5 by installation of the labile phosphate motif at later stage. The stereo chemistry is established by 5 steps chemo-enzyme combination synthesis to afford 99% optical purity, After then, the "S-form" compound OBI-3424 is prepared with improving overall yield of 54% from compound OBI-3424-5. The stereo chemistry is established by 4 steps combination of chemo-enzyme synthesis with excellent optical purity of 99%.
Patent CA-3131946-A1 (CA)
Inventor: MCDONALD MATTHEW LEE
IPC: A61N1/372
Filed: 2020-01-31
Abstract: Systems and techniques are disclosed to generate programming parameters and modifications during closed-loop adjustment of an implantable neurostimulation device treatment programming, through the identification and application of weights determined from user input indications and rankings of therapy objectives. In an example, a system to generate programming values of a neurostimulation device performs operations that: obtains human input which indicates multiple therapy objectives for neurostimulation treatment of a human patient; operates a model (such as an artificial intelligence model) to determine parameter outputs for programming of the neurostimulation device; identifies weights, based on the therapy objectives, usable in the model; produces a composite output from the model, by applying the identified weights to a combination of the parameter outputs of the programming model; and the resulting composite output provides neurostimulation device programming values for neurostimulation treatment designed to address the therapy objectives.
Patent CA-3132607-A1 (CA)
Inventor: NAJAFI MITRA
IPC: A61M1/02
Filed: 2020-03-06
Abstract: L'invention concerne un appareil de stockage de plasma riche en plaquettes (PRP). L'appareil est conçu pour recevoir de manière réversible un récipient à plasma riche en plaquettes (PRP). L'appareil comprend une plateforme délimitant au moins un renfoncement configuré pour recevoir le récipient à PRP ; et un agitateur configuré pour déplacer la plateforme, et ainsi agiter le PRP stocké dans le récipient à PRP. L'agitateur est conçu pour imprimer un mouvement circulaire à la plateforme selon une fréquence comprise entre 10 et 10 000 tours par minute (tr/min).
Patent CA-3132742-A1 (CA)
Inventor: VAN DER PLOEG LEONARDUS H T
IPC: G10H7/00
Filed: 2020-03-06
Abstract: L'invention concerne des dispositifs de traduction musicale en temps réel (RETM) et leurs procédés d'utilisation. Des utilisations à titre d'exemple de RETM comprennent l'optimisation de la compréhension et/ou du rappel d'un message d'entrée pour un utilisateur et l'amélioration d'un processus cognitif chez un utilisateur.
Patent CA-3136555-A1 (CA)
Title: Suspended theater edge actuated seat moving machine
Inventor: JENNINGS CLIFFORD ALLEN
IPC: A63G27/02
Filed: 2020-04-10
Abstract: A seat moving machine comprises a passenger seat assembly (160) disposed in between opposing seat supports (100a,100b) which raise and lower the passenger seat assembly (160). One or more passenger seat beam rotators (141) are operative to rotate the passenger seat assembly to change the pitch independently of the raising and lowering. In embodiments, rather that the seat rows being pivoted up with a rotating floor, a rotate function alters their mutual positions to one another while the lift function is taking place which brings the back seat rows up and over the front seat rows, allowing control over mutual row position during lift and in the show. Though no cables are involved, by combining the motions of lift and rotate and without any further equipment, an immersive theater system comprising the seat moving machine still employs seating that is suspended.
Patent CA-3139751-A1 (CA)
Title: Methods and systems for capturing biometric data
Inventor: PEIRCE MICHAEL
IPC: G06F21/32
Filed: 2012-01-19
Abstract: A method of authenticating users is provided that includes capturing biometric authentication data of a user and processing the captured biometric data into an image. Moreover, the method includes determining a region of interest of the image and a gray scale image from the image, determining an optimum transformation parameter set within the region of interest, and aligning the gray scale image with an enrollment gray scale image generated during enrollment of the user using results of the optimum transformation parameter set determination. Furthermore, the method includes extracting biometric feature data from the gray scale image and verifying an identity of the user with extracted biometric feature data included in a region of agreement.
Patent CA-3141591-A1 (CA)
Title: Apparatus, system and method regarding borehole muon detector for muon radiography and tomography
Inventor: SCHOUTEN DOUGLAS WILLIAM
IPC: G01V5/04
Filed: 2020-05-26
Abstract: A borehole muon detector for detecting and characterizing a geographic region of interest is provided, the borehole muon detector comprising a housing and sensor, which is housed in the housing, the sensor including: a plurality of photodetector elements; at least one printed circuit board in electrical communication with the plurality of photodetectors and including an integrated electronic circuit for tracking time; a first helical bundle of scintillator fibers; an oppositely wound helical bundle of scintillator fibers, the oppositely wound helical bundle, the first helical bundle and the opposite helical bundle defining an outer cylinder, which includes a first end and a second end and a bore therebetween, each scintillator fiber of each bundle directly optically connected to a photodetector element at least at one end and indirectly optically connected to the photodetector element at no more than one end; and a plurality of scintillator bars, each comprising a first end, a second end and an optical fiber extending from the first end to the second end, the plurality of scintillator bars vertically disposed in the bore of the outer cylinder, each optical fiber of the scintillator bar optically directly connected to a photodetector element at least at one end and indirectly optically connected to the photodetector at no more than one end.
Patent CA-3141989-A1 (CA)
Title: Compositions and methods for thymic regeneration and t-cell reconstitution
Inventor: FINNEGAN PAUL WILLIAM
IPC: A61K35/44
Filed: 2020-05-28
Abstract: The present invention provides non-thymic endothelial cells (ntECs) engineered to express adenovirus E4ORF1 and/or BMP4, and compositions comprising such engineered ntECs. The present invention also provides methods of using such ntECs in therapy, for example to enhance thymic regeneration (including T cell reconstitution) in subjects in need thereof. Such subjects include those that have a damaged thymus, defective thymic function, insufficient T-cell output, and/or that are immunocompromised - for example as a result of ageing, infection (e.g. with HIV), treatment with radiation therapy, treatment with chemotherapy, or myeloablative conditioning in preparation for an organ/tissue transplant.
Patent CA-3142200-A1 (CA)
Inventor: HOTTA DAISUKE
IPC: B01D71/64
Filed: 2020-05-29
Abstract: L'invention concerne une membrane d'osmose directe, un module de membrane d'osmose directe et son procédé de fabrication, une membrane d'osmose directe, ce qui permet d'obtenir une réduction extrêmement favorable de la diffusion inverse du sel par rapport à l'état de la technique et présente une perméabilité à l'eau prédéterminée, ce qui permet d'obtenir: du fait qu'une solution de matière première de type liquide utilisée dans des opérations de concentration réelle peut être concentrée avec une diffusion supprimée d'une solution d'induction même lorsqu'elle est utilisée plusieurs fois; et la durabilité en ce que les performances de la membrane peuvent être maintenues dans une plage prédéterminée même lorsqu'une solution de matière première ayant une pression osmotique est concentrée plusieurs fois. Selon un aspect, l'invention concerne une membrane d'osmose directe ayant une couche active de séparation polymère disposée sur la surface d'une membrane de support microporeuse, lorsque de l'eau purifiée est placée en tant que solution de matière première sur le côté de la couche active de séparation et 3,5% en masse d'une solution aqueuse de chlorure de sodium est placée sous la forme d'une solution d'induction sur le côté de la membrane de support, avec la membrane d'osmose directe entre celles-ci, la quantité R1 de diffusion inverse de sel dans la solution de matière première est de 0.65 g/(m2×hr) ou moins, et la quantité F1 de perméation de l'eau dans la solution d'induction est d'au moins 3.5 kg/(m2×hr).
Patent CA-3142271-A1 (CA)
Title: Non-hygroscopic crystalline salts of a pyrazole compound, and pharmaceutical compositions and use thereof
Inventor: SULLIVAN ROBERT
IPC: A61P35/00
Filed: 2020-06-02
Abstract: Provided herein are non-hygroscopic crystalline salts of (1r,4r)-N 1-(5-chloro-4-(5-(cyclopropylmethyl)-1-methyl-1H-pyrazol-4-yl)pyrimidin-2-yl)cyclohexane-1,4-diamine and pharmaceutical compositions thereof. Also provided are methods of their use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease.
Patent CA-3142448-A1 (CA)
Inventor: VAN BERKEL PATRICIUS HENDRIKUS CORNELIS
IPC: A61P35/00
Filed: 2020-06-04
Abstract: La présente invention concerne des conjugués anticorps-médicament (ADC) de pyrrolobenzodiazépines (PBD) conjugués à un anticorps qui se lie à KAAG1 (antigène 1 associé aux reins).
Patent CA-3144396-A1 (CA)
Title: System and method for ventilation
Inventor: SALSALI HAMIDREZA
IPC: F24F7/007
Filed: 2021-12-30
Abstract: A system including a housing that at least partially defines a cavity therein. The housing includes one or more apertures to permit air to circulate between the cavity and an external volume that is outside the housing. The system includes one or more fans for circulating the air through the cavity via the apertures.
Patent CA-3144949-A1 (CA)
Title: Monolithic organic porous ion exchanger
Inventor: TAKADA HITOSHI
IPC: B01J47/014
Filed: 2020-06-05
Abstract: This monolithic organic porous ion exchanger comprises a continuous skeleton and continuous pores, and is characterized in that: the continuous skeleton is formed by an organic polymer that is a hydrolyzate of a crosslinked polymer of (meth)acrylate ester and divinylbenzene and has either or both of the -COOH group and -COONa group as an ion exchange group; the thickness of the continuous skeleton is 0.1-100 µm; the average diameter of the continuous pores is 1.0-1,000 µm; the total pore volume is 0.5-50.0 mL/g; and the total ion exchange capacity of the -COOH group and -COONa group, on a dry weight basis, is at least 4.0 mg-equivalent/g. The present invention can provide a monolithic organic porous ion exchanger that exhibits an excellent absorbency for a target absorption liquid of, e.g., water, an aqueous solution, a hydrophilic organic solvent, and so forth.
Patent CA-3145094-A1 (CA)
Inventor: LIUKKULA MIKKO
IPC: B60C11/16
Filed: 2022-01-07
Abstract: The invention relates to an anti-skid stud (5) comprising a stud body (53) with a bottom flange (51) arranged to be placed in the bottom area of a stud hole (3) of a vehicle tyre (1), and a stem part (52) extending from the bottom flange, as well as a stud tip (54) fastened to the stud body. The stud tip (54) comprises a zone (55) in the longitudinal direction of the stud tip, whose cross-sectional shape is a variant of an angular polygon, symmetrical with respect to its mass centre, so that the distance from at least one vertex to the mass centre of the symmetrical polygon used as a starting point is greater than the distance from one or more other vertices.
Patent CA-3146262-A1 (CA)
Title: Method for producing light guage steel
Inventor: REHMAN KASHIF
IPC: C21D8/02
Filed: 2022-01-20
Abstract: The method is for use with a strip or plate of steel, the steel being of a composition and temperature suitable for heat treatment, and comprising the following steps:  ustenizing the strip or plate to produce austenitized material; quenching the austenized material to produce hardened steel; thermally tempering the hardened steel to produce tempered steel; and stretching and leveling the tempered steel to produce heat treated steel.
Patent CA-3146744-A1 (CA)
Inventor: LORD CHRISTOPHER
IPC: A24F40/65
Filed: 2013-10-09
Abstract: An electronic inhalation device which includes a mouthpiece and a control unit. The control unit includes a power cell and a computer, where the computer comprises a computer processor, a memory and an input-output means. The device further includes a transmitter connected to the computer and the computer is configured in use to collect and store use data relating to a user's use of the device in the computer memory and transmit the use data. The transmitter is configured to transmit the use data by wireless means. The electronic inhalation device is a heat-not-burn (HNB) device. The device includes a heating coil.
Patent CA-3147512-A1 (CA)
Inventor: KAUFFMANN AARON
IPC: G01N33/72
Filed: 2019-12-05
Abstract: A tangent flow hemolysis blood testing assembly, device and method are described herein. The presently disclosed and claimed inventive concept(s) relate to a device(s), kit(s), and method(s) for injecting a patient's liquid test sample into a reaction vessel. More specifically, the presently disclosed and claimed inventive concept(s) relate to an improved liquid test sample injection device that comprises a plug that forms an airtight seal that facilitates the active injection of a liquid test sample into a reaction vessel, and kits and methods of use related thereto.
Patent CA-3149457-A1 (CA)
Inventor: FLORES STEPHEN
IPC: B01L3/00
Filed: 2020-10-06
Abstract: A vial jacket configured to receive a label. The vial jacket includes a plastic material having a cryogenic operating temperature range, a hinge formed in the plastic material, a locking mechanism, and an opening formed in the plastic material. The plastic material is dimensioned to surround at least a portion of a vial. The hinge defines a first half shell having a first edge and a second half shell having a second edge. The locking mechanism is configured to secure the first edge of the first half shell to the second edge of the second half shell. The opening has an axial length and a transverse length.
Patent CA-3150424-A1 (CA)
Title: Formes a l'etat solide de (s)-2-(((s)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)amino)-n-(1-(2-methyl-1-(neopentylamino)propan-2-yl)-1h-imidazol-4-yl)pentanamide et utilisati ons assosiees
Inventor: GREER ELAINE
IPC: A61P35/00
Filed: 2019-08-09
Abstract: La présente invention concerne : a) des formes à l'état solide de sels de bromhydrate du composé 1; b) des compositions pharmaceutiques comprenant une ou plusieurs formes à l'état solide de sels de bromhydrate du composé 1, et, éventuellement, un excipient pharmaceutiquement acceptable; c) des méthodes de traitement de tumeurs ou de cancers par administration d'une ou de plusieurs formes à l'état solide de sels de bromhydrate du composé 1 à un sujet en ayant besoin; et d) des procédés de préparation des formes à l'état solide du composé 1.
Patent CA-3151035-A1 (CA)
Inventor: DUMOULIN-WHITE ROGER
IPC: A61K41/10
Filed: 2022-03-04
Abstract: A method for eliciting an immune response in a patient includes the sequential steps of: providing an immunogenic composition including an immunogen; adding a metal-based coordination complex to the immunogenic composition to inactivate or attenuate the immunogen; and administering the immunogenic composition to the patient so as to elicit the immune response against the immunogen. A method for preparing an attenuated immunogenic composition includes the steps of: providing an immunogenic composition including an immunogen; and adding a metal-based coordination complex to the immunogenic composition to inactivate or attenuate the immunogen in the immunogenic composition to provide the attenuated immunogenic composition.
Patent CA-3151102-A1 (CA)
Inventor: TRIP VINCENT
IPC: F28F9/22
Filed: 2020-08-24
Abstract: L'invention concerne un système modulaire d'écoulement de gaz comprenant au moins un premier et un second élément d'écoulement de gaz en forme cuboïde creuse. Les quatre bords d'au moins une face ouverte du premier élément d'écoulement de gaz sont reliés, de manière étanche aux gaz, à quatre bords d'une face ouverte du second élément d'écoulement de gaz en forme cuboïde creuse. Une soupape ou une cloison est présente au niveau des faces ouvertes en liaison. Le système d'écoulement de gaz peut être un collecteur d'un échangeur de chaleur à plaques.
Patent CA-3151609-A1 (CA)
Inventor: GREEN NICHOLAS
IPC: A61B17/221
Filed: 2020-09-25
Abstract: The present disclosure relates to catheter system comprising a balloon and an infusion basket designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a dmg delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis and thrombectomy.
Patent CA-3152967-A1 (CA)
Title: Method of machining a dental restoration with reduced contour falsification
Inventor: SCHNEIDER HANS-CHRISTIAN
IPC: A61C13/00
Filed: 2020-09-21
Abstract: The present invention relates to a method of machining at least one dental restoration (1) from a workpiece (2) using one or more dental tools (3), comprising: a step of defining a target contour (4) of the dental restoration (1); characterized by further comprising: a step of predicting the deflection of the dental tool (3) during pre-machining through a model based on one or more machining parameters; a step of determining based on the prediction step one or more primary locations (5) at which the target contour (4) would have been damaged during pre-machining; a step of modifying the target contour (4) or the corresponding machining path by adding an oversize of material (6) substantially only at the primary locations (5) for preventing damage; and a step of pre-machining the workpiece (2) based on the modified target contour (7) or the corresponding modified machining path.
Patent CA-3154301-A1 (CA)
Title: Tri cellulaire a base d'atp et cellules souches cancereuses hyperproliferantes
Inventor: LISANTI MICHAEL P
IPC: G01N33/574
Filed: 2020-09-14
Abstract: Dans la présente invention, un ATP mitochondrial élevé est un caractère métabolique qui confère une hyper-prolifération, un caractère souche, une indépendance d'ancrage, une capacité anti-oxydante et une résistance multi-médicament dans des cellules cancéreuses. Dans la présente approche, des niveaux d'ATP intracellulaire peuvent être utilisés en tant que biomarqueur métabolique pour identifier, séparer et purifier un phénotype de cellule souche cancéreuse (CSC) agressive et hyper-proliférative. En outre, l'ATP peut être combiné à d'autres marqueurs CSC, par exemple, à l'activité CD44 ou ALDH, pour fractionner avantageusement la population de CSC en sous-populations. Par exemple, les sous-populations de CSC d'ATP élévé/de CD44 élevé ont montré deux fois le niveau de croissance indépendante de l'ancrage par comparaison avec des sous-populations de CSC d'ATP bas/de CD44 élevé. L'invention concerne également des données bioinformatiques complémentaires qui impliquent la synthèse d'ATP mitochondrial dans le caractère souche, la métastase et la détection de cellules tumorales circulantes (CTC), ainsi qu'une signature génique de métastase liée à l'ATP à 5 chaînons (ABCA2, ATP5F1C, COX20, NDUFA2 et UQCRB). La signature génique de la présente approche peut être utilisée pour identifier des CSC présentant une augmentation spectaculaire de la migration cellulaire et une invasion in vitro, ainsi que des métastases spontanées in vivo. La présente invention concerne également une plate-forme cellulaire permettant de cibler systématiquement le caractère souche, la résistance multi-médicament et la métastase dans des cellules cancéreuses.
Patent CA-3154582-A1 (CA)
Title: Device for separation and removal impurities from granular material
Inventor: SOSNOWSKI WLODZIMIERZ
IPC: B07B7/10
Filed: 2022-04-08
Abstract: A device for separation and removal of light impurities from granular material has a cylindrical body (1), in the upper part of which is located a motor-driven fan (2) that sucks air and an outlet channel (4) for light impurities, below which there is axially mounted a feed channel (7) connected to a container (8) of granular material, and in the lower part of the body (1) there is axially located a cylinder (9) with an outer diameter smaller than the inner diameter (d) of the body (1), containing a centrifugal guide (11) located under the outlet (10) of the feed channel (7), whereas below the centrifugal guide, on the inner wall of the cylinder (9) are fixed uniformly spaced directing plates (13) at a certain distance from each other, their ends being pointed towards the axis of the device, and between the body (1) and the cylinder (9) there is a chute for purified material. There is a plurality of openwork hinder plates (14) fixed to the outer surface of the feed channel (7), in various transverse planes in each plane, their ends being pointed obliquely upwards towards the inner wall of the body (1), and inside the feed channel (7), above the outlet (10), there is axially placed a multi-conical reducer (16) slowing down gravitational flow of granular material.
Patent CA-3154910-A1 (CA)
Inventor: LANIGAN RICHARD
IPC: A61M39/10
Filed: 2013-03-07
Abstract: The fluid connector assembly (6010) for attaching tube sets to an infusion pump is disclosed. The fluid connector assembly includes a body portion (6018), a plug portion (6008) located on the body portion, the plug portion comprising a fluid path, and a tubing, a first end of the tubing fluidly connected to the plug fluid path.