baber/WOPTO huggingface dataset:
Patent WO-2021154942-A1 (WO)
Title: Systems, methods, and media for estimating a mechanical property based on a transformation of magnetic resonance elastography data using a trained artificial neural network
Inventor: MURPHY MATTHEW C
IPC: G01R33/28
Filed: 2021-01-28
Abstract: In accordance with some embodiments, systems, methods, and media for estimating a mechanical property based on a transformation of magnetic resonance elastography (MRE) data using a trained artificial neural network are provided. In some embodiments, a system is provided, the system comprising: a hardware processor programmed to: receive displacement data of tissue in vivo; provide the displacement data to a trained ANN that was trained using noisy input datasets as training data, and derivative datasets corresponding to the noisy input datasets to evaluate performance during training, such that the trained ANN provides an output dataset corresponding to an analytical solution to a derivative of a function represented in an unlabeled input dataset thereby transforming the unlabeled input dataset into its derivative; receive, from the trained ANN, an output dataset indicative of a derivative of the displacement data; and estimate stiffness of the tissue based on the derivative.
Patent WO-2021162980-A1 (WO)
Title: Polishing compositions and methods of use thereof
Inventor: HUANG TING-KAI
IPC: C03C15/00
Filed: 2021-02-08
Abstract: A polishing composition includes an abrasive; a pH adjuster; a barrier film removal rate enhancer; a low-k removal rate inhibitor; an azole-containing corrosion inhibitor; and a hard mask removal rate enhancer. A method of polishing a substrate includes the steps of: applying the polishing composition described herein to a surface of a substrate, wherein the surface comprises ruthenium or a hard mask material; and bringing a pad into contact with the surface of the substrate and moving the pad in relation to the substrate.
Patent WO-2022173428-A1 (WO)
Title: Alimentation de dispositif périphérique
Inventor: DAI FANGYONG
IPC: H02J3/00
Filed: 2021-02-10
Abstract: Dans un exemple selon la présente divulgation, un dispositif électronique est décrit. Un exemple de dispositif électronique comprend un processeur, un port permettant de recevoir un connecteur d'un dispositif périphérique, et une alimentation électrique. Un exemple d'alimentation électrique est l'alimentation du processeur et du dispositif périphérique lorsqu'il est connecté au dispositif électronique. Le dispositif électronique donné à titre d'exemple comprend également un dispositif de commande de dispositif électronique. Le dispositif de commande de dispositif électronique est destiné à modifier une quantité d'énergie d'une première valeur en une seconde valeur à fournir au dispositif périphérique sur la base d'une quantité d'énergie disponible provenant de l'alimentation électrique et d'un niveau d'alimentation seuil inférieur qui permet une communication de données à partir du dispositif périphérique. Le dispositif électronique donné à titre d'exemple comprend également un dispositif de commande de distribution d'énergie. Le dispositif de commande de distribution d'énergie est destiné à fournir la quantité d'énergie ayant la seconde valeur au dispositif périphérique sur la base d'une sortie provenant du dispositif de commande de dispositif électronique.
Patent WO-2021202008-A1 (WO)
Inventor: CARLO ROBERT MICHAEL III
IPC: A61B17/064
Filed: 2021-02-17
Abstract: Novel orthopedic staples and related instruments are disclosed. An instrument is an orthopedic drill guide assembly that includes a first arm and a second arm that are retractably connected to the distal end of the instrument's outer housing, where the proximal ends of the arms are retractably connected to the distal end of the outer housing and configured to move in a retractable motion that changes the spacing between the first drill guide sleeve and the second drill guide sleeve, where the proximal end of the outer housing is configured for controlling the retractable motion of the first and second arms.
Patent WO-2021178323-A1 (WO)
Inventor: MASE STEVE
IPC: G16H80/00
Filed: 2021-03-01
Abstract: Systems and methods for delivering timely personalized information about vulnerable persons to authorities and/or to caregivers. This may provide critical situational information in real or near real time to authorities and/or to caregivers in order to help increase public safety, reduce risks and/or improve the quality of life for vulnerable persons and parties responsible for the safety and well-being of the vulnerable persons.
Patent WO-2021188300-A1 (WO)
Title: Tail gas of gas fermentation to dry gasification feedstock
Inventor: GAO ALLAN HAIMING
IPC: C12N1/20
Filed: 2021-03-04
Abstract: The disclosure provides for the integration of a gas fermentation process with a gasification process whereby tail gas from the gas fermentation process is recycled to a dryer of the gasification process. The tail gas from the gas fermentation process is utilized to generate heat which in turn is used to dry feedstock to the gasification process. The heat is typically used to heat a drying gas, such as air, which is then directly or indirectly contacted with the gasification feedstock to dry the gasification feedstock. Dried gasification feedstock provides improved yield and improved quality of syngas as compared to gasification feedstock that is not dried.
Patent WO-2021183540-A1 (WO)
Title: Shingles vaccines comprising a tlr9 agonist
Inventor: CAMPBELL JOHN D
IPC: C12N15/113
Filed: 2021-03-09
Abstract: The present disclosure relates to immunogenic compositions comprising a varicella zoster virus (VZV) glycoprotein E antigen and a toll-like receptor 9 (TLR9) agonist, such as an oligonucleotide comprising an unmethylated cytidine-phospho-guanosine (CpG) motif. The immunogenic compositions are suitable for stimulating an immune response against VZV in an individual in need thereof.
Patent WO-2021183556-A1 (WO)
Title: Immunotherapeutic compositions and methods of production for coronavirus
Inventor: MOND JAMES
IPC: A61K39/395
Filed: 2021-03-09
Abstract: Embodiments of the present disclosure relate generally to compositions and methods for the treatment and/or prevention of pathogenic viral infections, e.g., coronavirus infections. In particular, the present disclosure provides human plasma compositions and immunoglobulin prepared therefrom containing select antibody titers specific for coronavirus (e.g., SARS CoV-2), methods of identifying human donors and donor samples for use in the compositions, methods of manufacturing the compositions, and methods of utilizing the compositions for prophylactic administration and/or therapeutic treatment (e.g., passive immunization or immune-prophylaxis).
Patent WO-2021183860-A1 (WO)
Title: Agents and compositions for the treatment of glioblastoma
Inventor: PLAS DAVID
IPC: C07K16/28
Filed: 2021-03-12
Abstract: Provided herein are compositions including a combination of therapeutic agents comprising a therapeutically effective amount of merestinib and a therapeutically effective amount of LY2584702. Also provided herein are methods of treating glioblastomas in a subject by administering the disclosed compositions, as well as methods of inducing cell death in a PTEN-deficient glioblastoma cell by administering the disclosed compositions.
Patent WO-2021194875-A1 (WO)
Title: Dispositifs et procédés d'occlusion au moins partielle d'une lumière corporelle
Inventor: BINMOELLER KENNETH
IPC: A61M25/00
Filed: 2021-03-19
Abstract: L'invention concerne des dispositifs et des procédés associés pour occlure au moins une partie d'une lumière corporelle pendant une procédure. Dans certains modes de réalisation, le dispositif comprend un corps de cathéter interne définissant une lumière à travers celui-ci et une première ouverture ; et un corps de cathéter externe comprenant un élément flexible et définissant une lumière à travers celui-ci et une seconde ouverture positionnée de manière proximale sur le corps de cathéter externe par rapport à l'élément flexible. Le corps de cathéter interne s'étend à travers la lumière du corps de cathéter externe, de telle sorte qu'au moins une partie du corps de cathéter externe peut être déplacée axialement vers et à l'écart de la partie distale du corps de cathéter interne. L'élément flexible est mobile entre une configuration non déployée et une configuration déployée lorsqu'au moins une partie du corps de cathéter externe est déplacée axialement vers ou à l'écart de la partie distale du corps de cathéter interne. Dans certains modes de réalisation, le dispositif et les procédés sont utilisés pour des procédures d'endoscopie.
Patent WO-2021202540-A1 (WO)
Title: Hsp70 inhibitors and methods of using same
Inventor: MURPHY MAUREEN E
IPC: A61K31/439
Filed: 2021-03-30
Abstract: The disclosure provides compounds, and compositions comprising such compounds, that can be used to treat cancer, especially colorectal cancer (CRC). In certain embodiments, the compounds of the disclosure inhibit HSP70. In other embodiments, the compounds of the disclosure promote or increase immune cell recruitment to a cancer. In yet other embodiments, the compounds of the disclosure promote or increase immune cell infiltration in a cancer.
Patent WO-2021207401-A1 (WO)
Inventor: POPMA SICCO HANS
IPC: C12N9/22
Filed: 2021-04-07
Abstract: L'invention concerne une construction polynucléotidique comprenant une ou plusieurs séquences de reconnaissance de nucléase en amont et en aval d'un multi-site d'édition de gènes qui comprend une pluralité de séquences de reconnaissance pour une recombinase spécifique d'un site ou d'une nucléase. La pluralité de séquences de reconnaissance permet l'insertion d'un ou de plusieurs gènes donneurs exogènes dans la cellule hôte.
Patent WO-2021221992-A1 (WO)
Inventor: TAHERZADEH BOROUJENI MAHMOUD
IPC: H04L5/00
Filed: 2021-04-22
Abstract: The present disclosure relates to selections of a channel state information (CSI) report setting option by a distinct demodulation reference signal (DMRS) pattern. Specifically, in one aspect, a user equipment (UE) may determine a CSI transmission setting based on the at least one measurement of the communication channel, the CSI transmission setting is associated with a distinct DMRS pattern, and transmit a CSI report with the distinct DMRS pattern to the network entity in accordance with the CSI transmission setting. In another aspect, a network entity may transmit CSI setting configuration information to a UE, the CSI setting configuration information including at least one parameter corresponding to a channel measurement threshold that triggers selection of a distinct DMRS pattern based on a CSI transmission setting, and receive a CSI report and the distinct DMRS pattern from the UE associated with the CSI transmission setting.
Patent WO-2021236293-A1 (WO)
Title: Dynamic cost-optimized true zero recovery time objective for multiple applications
Inventor: LIU BING
IPC: G06F11/20
Filed: 2021-04-23
Abstract: Data protection operations including replication operations that dynamically adapt a topology of replica virtual machines. A data protection system may implement a machine model that is trained using, as input, characteristics of virtual machines. When a failure is predicted, a topology of the replica virtual machines is changed. The topology may also change when changes in the environment are detected. The changes may include redistributing the protected applications to the replica virtual machines and/or scaling the replica virtual machines.
Patent WO-2022010671-A1 (WO)
Title: Techniques for supporting wideband array operation
Inventor: YERRAMALLI SRINIVAS
IPC: H04B7/04
Filed: 2021-06-25
Abstract: Methods, systems, and devices for wireless communications are described. To support a reliable array response for wideband communications, a base station may configure a set of transmission instances for a set of signals distributed across a wideband carrier bandwidth. At least one transmission instance of the set of transmission instances may be configured in each sub-band of the carrier bandwidth. The base station may transmit the set of signals in the configured transmission instances to a user equipment (UE). The UE may receive the set of signals distributed across the carrier bandwidth and may measure, for the signals, a set of signal measurements corresponding to the set of sub-bands. Based on the signal measurements, the UE may determine a set of communication beams for the set of sub-bands. Using one or more of the determined communication beams, the UE may communicate with the base station in the carrier bandwidth.
Patent WO-2022006120-A1 (WO)
Inventor: DEFRANCESCO JASON
IPC: A47K11/00
Filed: 2021-06-29
Abstract: The instant invention provides an improved toilet 10 that promotes ease and convenience of cleaning and promotes simplicity without clutter, by providing easy access to implements housed by the toilet. An example provides an access port 40 formed through a toilet wall, such as a cover 25 that allows passage of an implement, i.e., a toilet brush 55, stored within the toilet.
Patent WO-2022103451-A1 (WO)
Title: Procédés, systèmes et supports lisibles par ordinateur pour des messages de partie de commande de connexion de signalisation de classe 1 de partage de charge (sccp)
Inventor: CHAURASIA RAJEEV
IPC: H04Q3/00
Filed: 2021-07-14
Abstract: La présente invention concerne un procédé de partage de charge de messages SCCP de classe 1 comprenant la réception d'un message SCCP de classe 1 nécessitant une traduction d'appellation globale (GTT). Le procédé comprend la réalisation d'une GTT au niveau du message afin de sélectionner un groupe de partage de charge pour le message. Le procédé comprend en outre la génération d'une clé de partage de charge d'unité de signal de message (MSU) à l'aide de paramètres à partir d'une combinaison de paramètres de couche de partie de transfert de message (MTP) et de paramètres de couche de partie de commande de connexion de signalisation (SCCP). Le procédé comprend en outre l'utilisation de la clé de partage de charge MSU pour sélectionner une adresse de destination à partir du groupe de partage de charge pour le message. Le procédé comprend en outre l'insertion de l'adresse de destination dans le message. Le procédé comprend en outre le routage du message vers une destination correspondant à l'adresse de destination.
Patent WO-2022016075-A1 (WO)
Title: Universal oral care tool
Inventor: BLABAS BRETT C
IPC: A45D44/18
Filed: 2021-07-16
Abstract: A device for providing oral care includes at least one lumen fluidly coupled to a brush head. The lumen is adapted to suction fluid via an aperture disposed within the brush head. The brush head may be provided an oral cleaning fluid to facilitate cleaning of oral anatomy. The oral cleaning fluid may be provided within a cup provided within a containment assembly coupled to the oral care tool. Alternatively, or in addition, the cleaning fluid may be provided via fluid reservoir fluidly coupled to the oral care tool. The brush head comprises a bristles section and a foam section.
Patent WO-2022026746-A1 (WO)
Inventor: BASS DANIEL
IPC: A61B1/32
Filed: 2021-07-29
Abstract: An supine anterior-to-psoas approach includes a patient being rotated for the initial approach. Further, various blades and retractor rings provide various features to allow for the supine ATP approach or a conventional ATP to be performed.
Patent WO-2022055673-A1 (WO)
Title: Rocket mining system, subsystems, components and methods
Inventor: KUHNS MATTHEW
IPC: E21C51/00
Filed: 2021-08-17
Abstract: Mining apparatuses, systems, and methods related to using a rocket engine's plume and a collection manifold to efficiently displace, collect, process, and store frozen volatiles embedded within or below a surface are disclosed. The plume contacts and churns up the surface. The frozen volatiles are displaced and/or evaporated within a closed environment under a collection manifold. The collection manifold has related components for addressing these frozen or gaseous volatiles downstream. Various apparatuses and subsystems are also disclosed including a rover, processing plants, collection manifold, and vapor manifold.
Patent WO-2022076195-A1 (WO)
Title: Capteur laser à thermopile à accélération de temps de réponse et méthodes d'utilisation ainsi que procédé de fabrication
Inventor: GREENFIELD EPHRAIM
IPC: G01J1/42
Filed: 2021-09-28
Abstract: La présente invention divulgue un appareil capteur laser à thermopile amélioré et des méthodes d'utilisation. Selon un mode de réalisation, l'appareil comprend un corps de capteur comportant un premier évidement de corps de capteur et un second évidement de corps de capteur formés en son sein, un substrat étant positionné dans le premier évidement de corps de capteur en communication thermique avec le corps de capteur. Le substrat comprend au moins un absorbeur fixé à ce dernier et conçu pour absorber une partie d'un faisceau d'énergie laser. Un premier capteur thermique en communication thermique avec le substrat et avec le corps de capteur peut être formé sur le substrat ou fixé au substrat. Un second capteur thermique en communication thermique avec le corps de capteur peut être positionné dans le second évidement de corps de capteur. Une barrière thermique conçue pour réduire la vitesse de transfert d'énergie thermique du substrat au second capteur thermique peut être positionnée entre le substrat et le second capteur thermique.
Patent WO-2022146519-A1 (WO)
Title: Rognage sécurisé de chaîne de blocs dans un réseau à ressources limitées
Inventor: WHITE ERIC
IPC: H04W12/00
Filed: 2021-09-30
Abstract: Sur la base, au moins en partie, d'une détermination d'une quantité de stockage restant disponible dans un dispositif par rapport à un niveau particulier, un dispositif rogne au moins une partie de la chaîne de blocs à partir du dispositif y compris en rendant disponible le stockage attribué à la partie de la chaîne de blocs. Le dispositif recalcule la chaîne de blocs sans la partie de la chaîne de blocs qui a été rognée à partir du dispositif. En outre, le dispositif envoie un message à un autre dispositif participant à la chaîne de blocs, le message comprenant au moins le hachage pour la chaîne de blocs recalculée.
Patent WO-2022119634-A1 (WO)
Title: Model-based worst case execution time analysis for partitioned systems
Inventor: IKEGAMI MICHAEL
IPC: G06F9/48
Filed: 2021-10-06
Abstract: A system and method for calculating worst case execution times for actions in a process that is partitioned into a number of sub-processes that perform certain ones of the actions and operate on their own partition schedule independent of the other partitions. The method includes providing a unified modeling language (UML) activity diagram including the actions in the process, identifying each action in the diagram, determining each possible processing path for the actions in the process, assigning each action in each path to one of the sub-processes in the partitions, determining the time that each action will take through each path based on the partition schedule, and integrating the times for performing the actions in each of the paths. The method reports a longest time for performing the process along each path based on the integration of the times.
Patent WO-2022076733-A1 (WO)
Title: Cyproterone acetate compositions and uses thereof
Inventor: ROSENWALD LINDSAY
IPC: A61K47/10
Filed: 2021-10-07
Abstract: Provided herein are oral drug preparations including cyproterone acetate and ethinylestradiol, dosing regimen for the drug preparations, and methods of treating diseases. The methods provided include the administration of the oral drug preparation to treat one or more symptoms of hyperandrogenic conditions or hyperandrogenic activities, to provide contraception, and to reduce a risk of vascular thromboembolism (VTE) in a subject.
Patent WO-2022081478-A1 (WO)
Inventor: GRAY NATHANAEL S
IPC: A61K31/435
Filed: 2021-10-11
Abstract: The disclosure relates to compounds that act as covalent inhibitors of epidermal growth factor receptor (EGFR); pharmaceutical compositions comprising the compounds; and methods of treating or preventing kinase-mediated disorders, including cancer and other proliferation diseases.
Patent WO-2022094441-A1 (WO)
Title: Wound closure devices and methods of manufacturing and using same
Inventor: LEAR WILLIAM
IPC: A61B17/03
Filed: 2021-11-02
Abstract: A stress dispersing device includes an attachment section forming a first zone, a common section forming a second zone, and a plurality of rays extending from the common section and forming a third zone, wherein the first zone has a first stiffness, the second zone has a second stiffness and the third zone has a third stiffness, the first stiffness being greater than the second stiffness, and the second stiffness being greater than the third stiffness.
Patent WO-2022103772-A1 (WO)
Inventor: PRINCE MATTHEW
IPC: A61B34/20
Filed: 2021-11-09
Abstract: L'invention concerne des dispositifs, des systèmes et des procédés associés pour minimiser ou empêcher la contamination de dispositifs médicaux stériles pendant leur magnétisation. Par exemple, l'invention concerne un couvercle de magnétiseur pour maintenir la stérilité d'un dispositif médical tout en magnétisant le dispositif médical. Le couvercle de magnétiseur peut comprendre une base, un entonnoir s'étendant depuis la base, et une languette de préhension s'étendant depuis la base. La base comprend une interface de dispositif médical et une interface de magnétiseur opposée à l'interface de dispositif médical. L'entonnoir comprend une tige d'entonnoir configurée pour protéger un dispositif médical allongé d'entrer en contact avec un magnétiseur lorsque le dispositif médical est inséré dans l'entonnoir. La languette de préhension est configurée pour manipuler le couvercle de magnétiseur.
Patent WO-2022120136-A1 (WO)
Title: Procédé de préparation de pralsétinib
Inventor: WAETZIG JOSHUA
IPC: C07C257/06
Filed: 2021-12-03
Abstract: En partie, l'invention concerne des composés et des compositions utiles pour la préparation de pralsétinib. L'invention concerne également des procédés de préparation de pralsétinib.
Patent WO-2022140118-A1 (WO)
Title: Compositions and methods for treating patients with mitochondrial complex i deficiency using caspase-9 signaling pathway inhibitors
Inventor: TROY CAROL M
IPC: C07K14/705
Filed: 2021-12-14
Abstract: The present disclosure relates to a method for treating mitochondrial complex I deficiency comprising administering to patients with mitochondrial complex I deficiency an effective amount of XBIR3. The effective amount of XBIR 3 may be conjugated to a cell-penetrating peptide, such conjugation may include encapsulation of XBIR3 in nano-carrier that is conjugated to a cell penetrating peptide or direct conjugation of XBIR3 to a cell penetrating peptide. The XBIR-3 conjugated to a cell-penetrating peptide may be administered directly to the eye of the patient, administered systemically, or administered intranasally.
Patent WO-2021174256-A1 (WO)
Inventor: ABOTABL AHMED ATTIA
IPC: H04W72/04
Filed: 2021-02-26
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may determine an energy per resource element (EPRE) value for a slot based at least in part on whether the slot is associated with a half-duplex configuration or a full-duplex configuration, wherein the EPRE value is a first value when the slot is associated with the half-duplex configuration and a second value when the slot is associated with the full-duplex configuration; and perform a communication in the slot in accordance with the EPRE value. Numerous other aspects are provided.