baber/WOPTO huggingface dataset:
Patent CA-2673558-A1 (CA)
Inventor: HAUSDORFF WILLIAM P
IPC: A61K39/09
Filed: 2007-12-10
Abstract: An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) conjugated to a carrier protein. The immunogenic composition, formulated as a vaccine, increases coverage against pneumococcal disease in infants and young children globally, and provides coverage for serotypes 6A and 19A that is not dependent on the limitations of serogroup cross-protection. Also described is a method for making an immunogenic conjugate comprising Streptococcus pneumoniae serotype 1 polysaccharide covalently linked to a carrier protein, the method including partial de-O-acetylation of the polysaccharide by mild hydrolysis in an alkaline pH buffer.
Patent CA-2673704-A1 (CA)
Inventor: HARE RONALD G
IPC: F21S8/10
Filed: 2008-02-21
Abstract: A lamp assembly including a plurality of light sources, a plurality of light guides, and at least one lens. The plurality of light guides are optically connected to the plurality of light sources, and selected plurality of light sources emit light that is selectively propagated through the plurality of light guides. The at least one lens is optically connected to the plurality of light guides.
Patent CA-2675676-A1 (CA)
Title: Nicotinic acetylcholine receptor modulators
Inventor: MICCO IOLANDA
IPC: A61K31/4155
Filed: 2008-01-16
Abstract: The present invention provides compounds of formula (I) and compositions thereof, methods of making them, and methods of using them to modulate alpha7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.
Patent CA-2676674-A1 (CA)
Inventor: WALSH DAVID
IPC: G02F1/35
Filed: 2007-01-26
Abstract: A coating (10) between a nonlinear crystal (5) and a silicon prism coupler (9), prevents transmission of radiation scattered within the crystal (5) by filtering out frequencies outside the silicon bandgap to avoid free carrier absorption, but transmits THz frequencies that correspond to the bandgap.
Patent CA-2677940-A1 (CA)
Title: Electrochemical supercapacitor/lead-acid battery hybrid electrical energy storage device
Inventor: KHARISOV GAMIR GALIEVICH
IPC: H01G4/005
Filed: 2008-02-15
Abstract: A hybrid lead-acid battery/electrochemical capacitor electrical energy storage device. The lead-acid battery and electrochemical capacitor reside in the same case and are electrically connected. Preferably, a hybrid device of the present invention includes at least one non-polarizable positive electrode, at least one non-polarizable negative electrode, and at least one polarizable electric double layer negative electrode. Separators reside between the electrodes and the separators and electrodes are impregnated with an aqueous sulfuric acid electrolyte. A hybrid device of the present invention exhibits high power characteristics.
Patent CA-2678100-A1 (CA)
Title: Bicyclic oxomorpholine derivative
Inventor: KAWANO KOKI
IPC: A61K31/5375
Filed: 2008-02-27
Abstract: ABSTRACT The present invention relates to a compound represented by formula (I): wherein R1 represents a C1-3 alkyl group, R2 represents a hydrogen atom or a C1-3 alkyl group, Ar represents a phenyl group or the like which may be substituted with 1 to 3 substituents, X represents an oxygen atom or the like, n and m are the same or different and integers of 0 to 2, or a pharmacologically acceptable salt, and use thereof as a medicament.
Patent CA-2679097-A1 (CA)
Inventor: ANTWILER GLEN DELBERT
IPC: C12M1/26
Filed: 2008-01-28
Abstract: A disposable apparatus for cell expansion, having at least one bioreactor. The bioreactor has a cellular growth area and a supply area, the cellular growth area being separated from said supply area by a membrane. A fluid recirculation path in fluid communication with the cellular growth area allows for hermetically removing a sample containing cellular matter. This may comprise an elongated tube, or a plurality of parallel tube segments. The parallel tube segments have inflow ends and outflow ends, and the inflow ends are joined at a first common juncture and the outflow ends are joined at a second common juncture. The common junctures may comprise valves.
Patent CA-2681854-A1 (CA)
Inventor: PAHL GUENTER
IPC: B64C1/26
Filed: 2008-04-21
Abstract: A wing-fuselage section of an aircraft, which wing-fuselage section comprises a wing root (7, 8) at which the wing (1) of the aircraft is connected to the fuselage (2), a fuselage region (3) with fuselage frame elements (11-15, 21-25) that extent across the longitudinal direction of the aircraft, and a wing region (5, 6) with spars (16-19, 26-29) that extend in the direction of the wingspan. According to the invention, the spars (16- 19, 26-29) of the wing region (5, 6) and the fuselage frame elements (11-15, 21-25) of the fuselage region (3) form part of an integral assembly (40) that extends at least over a middle part of the wing (1) and the fuselage region (3), including the wing roots (7, 8).
Patent CA-2683994-A1 (CA)
Title: System and method for water breakthrough detection and intervention in a production well
Inventor: LEE JAEDONG
IPC: E21B47/10
Filed: 2008-04-18
Abstract: A system and method for estimating an occurrence of a water breakthrough in a production well (50) is provided that includes estimating, at least periodically, a measure of water in the fluid produced from one or more production zones (52a, 52b) and estimating the occurrence of the water breakthrough utilizing at least in part a trend of the estimated measures of the produced fluid. A controller (150) determines one or more actions to be taken to mitigate an effect of the water breakthrough and may automatically initiate one or more such actions.
Patent CA-2685413-A1 (CA)
Inventor: KANKAN RAJENDRA NARAYANRAO
IPC: C07D495/04
Filed: 2008-05-07
Abstract: There is provided a process for preparing dorzolamide and processes for preparing intermediates useful in the preparation of dorzolamide. In particular, there is provided a process for preparing an acetoamido sulfone of formula (viii) comprising oxidation of a hydroxysulfonamide of formula (vii) in the presence of an oxidizing agent selected from the group consisting of: a peracid, tert-butyl hydroperoxide, dimethyl dioxirane, selenium dioxide, m-phenanthroline di-N-oxide, nitric acid and hydrogen peroxide. There is also provided a process for preparing an acetoamidosulfone of formula (ix-a) comprising converting a hydroxysulfone of formula (viii) to the acetoamidosulfone of formula (ix-a) in the presence of acetonitrile and an acid. There is also provided a process for separating the cis- and trans-isomers of dorzolamide from a mixture of the trans-isomer of dorzolamide and the cis-isomer of dorzolamide comprising reacting the mixture of isomers with a carboxylic acid.
Patent CA-2685677-A1 (CA)
Inventor: ZHANG LI
IPC: G01N21/27
Filed: 2008-04-15
Abstract: Systems and methods are described for measuring pH of low alkalinity samp les. The present invention provides a sensor array comprising a plurality of pH indicators, each indicator having a different indicator concentration. A calibration function is generated by applying the sensor array to a sample solution having a known pH such that pH responses from each indicator are si multaneously recorded versus indicator concentration for each indicator. Onc e calibrated, the sensor array is applied to low alkalinity samples having u nknown pH. Results from each pH indicator are then compared to the calibrati on function, and fitting functions are extrapolated to obtain the actual pH of the low alkalinity sample.
Patent CA-2689158-A1 (CA)
Inventor: RODGERS JAMES D
IPC: A61K31/519
Filed: 2008-06-12
Abstract: The present invention provides active metablites of 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.
Patent CA-2689442-A1 (CA)
Inventor: GOROKHOV ALEXEI
IPC: H04W36/00
Filed: 2008-06-25
Abstract: Systems and methodologies are described that facilitate recovering from error due to false detection of completion signals at an access terminal. An access terminal specific request signal can be sent to a target base station to initiate handoff or semi-connected state exit. A completion signal can be transferred in response to the access terminal specific request signal. To mitigate errors stemming from false detection of the completion signal at the access terminal, forward link and reverse link confirmation signals can be transferred to confirm successful handoff or connected state re-entry completion. For example, the access terminal can determine handoff or re-entry to be successful when a forward link confirmation signal is detected prior to expiration of a timer. Moreover, the forward link and reverse link confirmation signals can each include more CRC bits as compared to a number of CRC bits included in the completion signal.
Patent CA-2690241-A1 (CA)
Inventor: NIELSEN JENS BREDAL
IPC: C12P17/04
Filed: 2008-06-12
Abstract: The present invention relates to novel tools for improving MPA production. In particular, the present invention relates tofungal enzymes that are specific for MPA synthesis.
Patent CA-2690915-A1 (CA)
Inventor: MAHIEU PIERRE
IPC: C01B32/50
Filed: 2008-05-27
Abstract: Le procédé commande le centre (23) de traitement des fumées (CTF) épurant les fumées de cuisson d'un four (1) à cuire (FAC) à feu tournant dont les fumées sont aspirées par au moins une rampe (11) d'aspiration du FAC (1) et collectées dans un conduit (20, 20') les dirigeant au CTF (23) comportant une tour (24) de refroidissement des fumées par pulvérisation d'eau dans les fumées, et au moins un réacteur (25) de neutralisation physico-chimique des fumées par mise en contact avec un réactif pulvérulent, tel l'alumine, puis filtrage (36) du réactif chargé et des poussières des fumées, et recyclage dans le réacteur (25) d'au moins une fraction du réactif filtré et son mélange à du réactif frais, le procédé comprenant au moins les étapes consistant à réguler le débit d'eau dans la tour (24) de refroidissement, et/ou réguler le débit et/ou le taux de recyclage du réactif dans le réacteur (25), en fonction d'au moins un paramètre indicateur d'un niveau de pollution des fumées à l'entrée du CTF (23). Application à la cuisson des anodes et cathodes en carbones pour l'électrolyse de l'aluminium.
Patent CA-2696768-A1 (CA)
Title: Composition for treating lung cancer, particularly of non-small lung cancers (nsclc)
Inventor: BARNER MARIJKE
IPC: A61K39/00
Filed: 2008-10-08
Abstract: The present invention relates to an active (immunostimulatory) composition comprising at least one RNA, preferably a mRNA, encoding at least two (preferably different) antigens capable of eliciting an (adaptive) immune response in a mammal. The invention furthermore relates to a vaccine comprising said active (immunostimulatory) composition, and to the use of said active (immunostimulatory) composition (for the preparation of a vaccine) and/or of the vaccine for eliciting an (adaptive) immune response for the treatment of lung cancer, particularly of non-small cell lung cancers (NSCLC), preferably selected from the three main sub-types squamous cell lung carcinoma, adenocarcinoma and large cell lung carcinoma, or of disorders related thereto. Finally, the invention relates to kits, particularly to kits of parts, containing the active (immunostimulatory) composition and/or the vaccine.
Patent CA-2698070-A1 (CA)
Inventor: CAUDWELL CHRISTOPHER HUGH
IPC: B65B53/02
Filed: 2008-09-02
Abstract: A hot water shrink tunnel (10) includes a housing (11) in which there is a heat chamber. The heat chamber housing (11) has an inlet opening (12) and spaced therefrom an outlet opening (13).  Each opening (12/13) is closed by an end closing device (21) in the form of a curtain and through which product can pass. A conveyor (14) enables product to be conveyed through the heat chamber from inlet opening (12) to outlet opening (13). An external duct (17) is mounted adjacent end opening (12) and similarly a duct 19 adjacent end opening (13). Each duct includes a shroud (19) of a size and design to capture hot water vapour which, in use of the shrink tunnel, issues through the end opening (12/13) when product passes through the curtain. The heat chamber does not require a flue or venting to atmosphere.
Patent CA-2699961-A1 (CA)
Inventor: TURSKI LECHOSLAW A
IPC: C07C291/04
Filed: 2008-06-23
Abstract: The invention concerns venlafaxine-N-oxide and O-desmethylvenlafaxine-N-oxide as prodrugs of venlafaxine and its major (active) metabolite O-desmethylvenlafaxine respectively, to pharmaceutical compositions containing these N-oxides, to methods for preparing them, and methods for preparing compositions. The invention relates to N-oxide, having formula (1), wherein R1 is H or CH3, and tautomers, stereoisomers, hydrates and solvates thereof. The invention also relates to the uses of the N-oxides and compositions, particularly for the manufacture of medicaments useful in the treatment of affections or diseases effectively treatable -albeit with side effects - with venlafaxine.
Patent CA-2699977-A1 (CA)
Title: Dispositifs de perforation
Inventor: COOK JOHN
IPC: F42B39/14
Filed: 2008-07-09
Abstract: L'invention concerne des dispositifs de perforation pour atténuer la réaction explosive d'un boîtier, corps tubulaire ou contenant, en particulier une munition, lorsqu'il est soumis à une menace dangereuse thermique externe. Les dispositifs se basent sur l'utilisation d'alliages à mémoire de forme. Le dispositif comprend un élément d'alliage à mémoire de forme qui est réuni à un connecteur pour former un anneau, qui peut être situé sur une surface extérieure d'une douille de munitions ou lanceur de minutions de telle sorte qu'un chauffage à travers sa plage de température de transition amènera l'anneau à se contracter radialement vers l'intérieur, perforant ainsi la munition, permettant à une quelconque accumulation de pression d'être relâchée rapidement. Avantageusement, le connecteur est inversible de telle sorte que le dispositif sera capable d'être modernisé ou retiré pendant une utilisation normale de la munition.
Patent CA-2706296-A1 (CA)
Inventor: KOTT HORST
IPC: B64C1/00
Filed: 2007-11-29
Abstract: According to an exemplary embodiment of the present invention, a diagnosis system for detecting a state of emergency during assembly of a fuselage (101) of an airplane is provided, which is adapted for detecting an emergency event and outputting information relating to the actual position of the emergency event. This may provide for a fast error identification during airplane assembly.
Patent CA-2707041-A1 (CA)
Inventor: CORONADO MARTIN P
IPC: H01B11/22
Filed: 2008-11-24
Abstract: A fiber optic cable includes at least one optic fiber; and a buoyancy modifying coating on the at least one optic fiber, the coating comprising at least one microballoon and a matrix material.
Patent CA-2707058-A1 (CA)
Title: A led lamp
Inventor: HE JIAN
IPC: F21K99/00
Filed: 2010-06-22
Abstract: The invention discloses a LED lamp, including: a lamp body has illuminating surface and reflective panel, wherein the reflective panel reflects light then transmits by illuminating surface, both sides of reflective panel have axial strip-shaped notch while both ends of lamp body have lamp holder; two LED luminous components, cooperatively installed inside the strip-shaped notch of lamp body and the illuminating surface turns to reflective panel; a drive circuit installed inside lamp holder, and electrically connects with luminous components and illuminates LED luminous components. The light from LED light source of the invention transmits from illuminating surface after the diffuse reflection from reflective panel and multiple refractions from solid lamp body, increasing light-emitting area, and lights are bright, mild and even; with effectual lighting, lower power consumption, longer life-span and good for eyes, the invention is applicable widely to house, office, market, carriage with great economic and social benefit.
Patent CA-2707673-A1 (CA)
Title: Analyse permettant de detecter les acides nucleiques libres en circulation
Inventor: DUVDEVANI AMOS
IPC: C12Q1/68
Filed: 2008-12-04
Abstract: La présente invention concerne, entre autres, des procédés et des trousses utiles pour des méthodes rapides, simples et économiques de quantification de tous les acides nucléiques libres, entre autres, dans des échantillons de liquides biologiques.
Patent CA-2707913-A1 (CA)
Title: Composition polyamide stabilisee vis-a-vis de la chaleur et de la lumiere
Inventor: PEDUTO NICOLANGELO
IPC: C08L77/00
Filed: 2008-12-01
Abstract: L'invention concerne une composition polyamide stabilisée vis-à-vis de la chaleur et de la lumière comprenant un système de stabilisation comprenant de l'oxyde de cuivre et du KBr, présentant un excellent maintien des propriétés mécaniques après une exposition à la chaleur ou à la lumière. L'invention concerne aussi un procédé de fabrication de ces compositions et notamment l'utilisation de ces compositions pour la réalisation d'articles dans le domaine de l'automobile.
Patent CA-2710634-A1 (CA)
Title: Individually packaged absorbent article assembly
Inventor: FUNG PAUL Y
IPC: B65D85/07
Filed: 2010-07-19
Abstract: An individually packaged absorbent article assembly including a tri-folded absorbent article having two end portions and an intermediate portion, and a pouch containing the tri-folded absorbent article, the pouch be structured and arranged to enable a user to selectively open the pouch to thereby expose a garment-facing surface of the intermediate portion of the absorbent article prior to exposing a garment facing surface of either of the end portions of the absorbent article.
Patent CA-2711778-A1 (CA)
Inventor: EBIIKE HIROSATO
IPC: A61P35/00
Filed: 2009-02-06
Abstract: A preventive or therapeutic agent of a proliferative disease such as cancer, having superior P13K inhibitory effects, superior cell proliferation inhibitory action as well as superior stability in a body and water solubility, is provided.   A compound represented by formula (I):    (see formula I) [wherein, Q represents a linking group represented by -X-Y-; X represents a single bond -CO-, -CONH-, -CON(C1-4alkyl)-, -CS-, -CSNH-, -CSN(C1-4 alkyl)-, or -SO2-;  Y represents a single bond, arylene or heteroarylene; provided that X and Y  are not simultaneously single bonds; and R1 represents -C0-6 alkylene-(A)m-C1-6 alkyl, or C0-6 alkylene-(A)m-C0-6 alkylene-(heterocycle)] or a pharmaceutically acceptable salt thereof.
Patent CA-2712783-A1 (CA)
Inventor: BLIZZARD TIMOTHY A
IPC: C07D487/08
Filed: 2009-01-15
Abstract: Substituted bicyclic beta-lactams of Formula I: are .beta.-lactamase inhibitors, wherein a, X, R1 and R2 are defined herein. The compounds and pharmaceutically acceptable salts thereof are useful in the treatment of bacterial infections in combination with .beta.-lactam antibiotics. In particular, the compounds can be employed with a .beta.-lactam antibiotics (e.g., imipenem, piperacillin, or ceftazidime) against microorganisms resistant to .beta.-lactam antibiotics due to the presence of the .beta.-lactamases.
Patent CA-2713083-A1 (CA)
Title: Semiconductor materials prepared from rylene-(.pi.-acceptor) copolymers
Inventor: FACCHETTI ANTONIO
IPC: H01L51/05
Filed: 2009-02-05
Abstract: Disclosed are new semiconductor materials prepared from rylene-(.pi.-acceptor) copolymers. Such copolymers can exhibit high n-type carrier mobility and/or good current modulation characteristics. In addition, the polymers of the present teachings can possess certain processing advantages such as solution-processability and/or good stability at ambient conditions.
Patent CA-2713353-A1 (CA)
Inventor: AKKERMANS JOHANNES A G
IPC: G08B13/14
Filed: 2008-12-30
Abstract: A radio-frequency integrated circuit chip package has N integrated aperture-coupled patch antennas, N being at least two, and includes N generally planar patches, and at least one generally planar ground plane. The ground plane is formed with at least N coupling aperture slots therein. N feed lines are spaced inwardly from the ground plane and substantially parallel thereto, and at least one radio-frequency chip is spaced inwardly from the feed lines and coupled to the feed lines and the ground plane. A first substrate layer is formed with the chip located in a chip-receiving cavity. A second substrate layer is interposed be-tween the ground plane and a plane defined by the patch. The patch is formed in a first metal layer, the ground plane in a second metal layer, and the second substrate layer defines an antenna cavity in which the N generally planar patches are located.
Patent CA-2714466-A1 (CA)
Inventor: FRANCINO PETER N
IPC: F22B35/18
Filed: 2010-09-08
Abstract: An optimization and control system for a utility plant that uses fan based air cooled condensers controls the operation of the power generation system at the plant in conjunction with the operation of the air cooled condensers so as to run the power plant at an optimum operating point associated with minimizing or reducing the cost of each kilowatt-hour of energy or other useful energy produced by the plant. The optimization and control system includes an optimizer having a numerical solver that determines values for a set of control variables associated with an optimal operating point of the plant and an expert system that oversees and modifies the control variable settings prior to providing these settings to a plant controller. The numerical solver uses an objective function and one or more models of plant equipment to determine the operating point of the plant that minimizes the cost per unit of useful energy generated by the plant. As part of determining the optimal plant operating point, the numerical solver may determine the number of fans to run within the air cooled condensers of the plant and/or the speed of the fans to use in the air cooled condensers in conjunction with the amount of fuel to burn in the boiler, the desired temperature of the steam at the input of the steam turbine, etc., all required to produce a given amount of power (load demand) at the particular environmental conditions currently experienced at the plant. The expert system may modify these outputs by determining which fans to actually use at any particular time based on, for example, the availability of or the operational status of the fans, the wear of the fans and fan motors, etc.
Patent CA-2715484-A1 (CA)
Inventor: SAINT-REMY JEAN-MARIE
IPC: A61K39/39
Filed: 2009-02-16
Abstract: La présente invention concerne l'utilisation de peptides immunogènes comprenant un épitope de lymphocyte T dérivé d'un antigène de vecteur viral et un motif redox tel que C-(X)2-[CST] ou [CST]-(X)2-C, d'une part pour la prévention et/ou la suppression des réponses immunitaires dirigées contre des vecteurs viraux, et d'autre part pour la fabrication de médicaments à cet effet.
Patent CA-2715667-A1 (CA)
Inventor: GYRN STEFFEN
IPC: A61M5/142
Filed: 2009-02-19
Abstract: The invention relates to an insertion device comprising - a penetrating member (50) connected to transformation means (52), - a moving part (38) comprising guiding means (39) which guiding means (39) restrict the movement of the transformation means (52) and guide the penetrating member (50) from a first to a second position in a first direction, i.e. the direction of insertion, towards the injection site, and - a stationary housing (30) comprising guiding means (32) which guiding means (32) restrict the movement of the moving part (38). The guiding means (32) guide the moving part (38) in a second direction which is linear and different from the first direction i.e. the direction of insertion.