baber/WOPTO huggingface dataset:
Patent EP-3986925-A1 (EP)
Title: Method for the generation of a trivalent antibody expressing cell by targeted integration of multiple expression cassettes in a defined organization
Inventor: AUER JOHANNES
IPC: C07K16/00
Filed: 2020-06-17
Abstract: Herein is reported a method for producing a trivalent antibody comprising the steps of cultivating a mammalian cell comprising a deoxyribonucleic acid encoding the trivalent antibody, and recovering the trivalent antibody from the cell or the cultivation medium, wherein the deoxyribonucleic acid encoding the trivalent 5 antibody is stably integrated into the genome of the mammalian cell and comprises in 5'- to 3'-direction a first expression cassette encoding the first heavy chain, a second expression cassette encoding the first light chain, a third expression cassette encoding the first light chain, a fourth expression cassette encoding the second heavy chain, a fifth expression cassette encoding the second light chain, and a sixth 10 expression cassette encoding the second light chain, wherein the first heavy chain comprises from N- to C-terminus a first heavy chain variable domain, a CH1 domain, a first light chain variable domain, a CH1 domain, a hinge region, a CH2 domain and a CH3 domain, the second heavy chain comprises from N- to C-terminus the first heavy chain variable domain, a CH1 domain, a hinge region, a CH2 domain and a 15 CH3 domain, the first light chain comprises from N- to C-terminus a second heavy chain variable domain and a CL domain, and the second light chain comprises from N- to C- terminus a second light chain variable domain and a CL domain, wherein the first heavy chain variable domain and the second light chain variable domain form a first binding site and the second heavy chain variable domain and the first 20 light chain variable domain form a second binding site.
Patent EP-3997557-A1 (EP)
Inventor: THORPE THOMAS
IPC: G06F3/0354
Filed: 2020-07-09
Abstract: The invention relates to a tactile interface (1) comprising a touch pad (3) and a support (2), the touch pad (3) being hingedly attached to the support (2) between an extended active position and a retracted inactive position, in which the pad (3) is folded back towards the support.
Patent EP-3990068-A1 (EP)
Title: Système et procédé de fabrication d'un dispositif d'inhalation
Inventor: PARKER MATTHEW DANSON
IPC: B65D83/06
Filed: 2020-06-24
Abstract: L'invention concerne un procédé de fabrication d'un dispositif d'inhalation comprenant les étapes consistant à : disposer un support de médicament avec un premier élément, le support étant relié à une couche; mettre en prise un second élément avec le premier élément pour supporter la couche intermédiaire, le second élément comprenant une surface de coupe et définissant une cavité; et déplacer le support par rapport aux éléments afin de le disposer avec la cavité et couper la couche autour du support. Dans certains modes de réalisation, l'invention concerne des systèmes et un appareil de fabrication, des dispositifs d'inhalation et d'administration, et des médicaments.
Patent EP-3997252-A1 (EP)
Inventor: VECCHIO JAMES NATHANIEL
IPC: C22C38/00
Filed: 2020-07-07
Abstract: Disclosed herein are embodiments of alloys configured to form a coating with two contrasting physical behaviors: 1) reduced hardness with the end result of an easily machinable coating and 2) high abrasion resistance. Generally low hardness will result in low abrasion resistance. However, embodiments of the alloys described herein are able to maintain a low hardness while exhibiting higher abrasion resistance.
Patent EP-3914925-A1 (EP)
Inventor: ALMERS PETER
IPC: G01S13/88
Filed: 2020-01-24
Abstract: An autonomous moving object comprising a radar sensor is provided. The radar sensor is configured to, during movement, acquire data sets representing reflections from surface portions located within a distance range, and, at least at a sequence of occasions, illuminate a surface region and acquire a data set representing, for each of a set of distances within said distance range, an amplitude and a phase of reflected radar signals received from surface portions located at said distance. Said surface regions comprise a common sub-region illuminated at each of said occasions. A radar signal processor is configured to receive the data sets acquired at each of said sequence of occasions. The received data sets form a collection of data sets, wherein each data set of said collection comprises a data subset pertaining to said common sub-region. A surface classifier processor is configured to output a classification of a surface type of the surface based on said collection of data subsets.
Patent EP-4003360-A1 (EP)
Inventor: DYHRFJELD-JOHNSEN JONAS
IPC: A61K31/538
Filed: 2020-07-24
Abstract: The present invention relates to the therapeutic use of azasetron or an analogue thereof for treating and/or preventing a lesion in the central auditory nervous system (CANS). The inventors show that treatment of lesions in the CANS with azasetron allows reducing the loss of neurons in the brainstem.
Patent EP-3973252-A1 (EP)
Title: Signalisierungsvorrichtung
Inventor: STUDNICKA MICHAL
IPC: G01D5/165
Filed: 2020-07-16
Abstract: Signalisierungsvorrichtung (1), welche dazu eingerichtet ist, ein Auswahlsignal (3) mittels einer analogen Auswahlvorrichtung (4) zur Wahl eines Signalbereichs zu erzeugen, und eine Bereichsskala (10) zur Anzeige des durch die analoge Auswahlvorrichtung (4) gewählten Signalbereichs, wobei die Bereichsskala (10) zumindest zwei Einstellbereichen (11-14) und zumindest einen Übergangsbereich (21-23) aufweist, wobei jeweils ein Einstellbereich von den zumindest zwei Einstellbereichen (11-14) alternierend mit jeweils einem Übergangsbereich von dem zumindest einen Übergangsbereich (21-23) längs einer Erstreckung der Bereichsskala (10) angeordnet sind, und die analoge Auswahlvorrichtung (4) so angeordnet ist, dass eine Auswahl eines Einstellbereichs (11-14) oder eines Übergangsbereichs (21-23) längs der Erstreckung der Bereichsskala (10) erfolgt und die analoge Auswahlvorrichtung (4) dabei einen analogen Auswahlwert (5) festlegt, und die Signalisierungsvorrichtung (1) ferner dazu eingerichtet ist, den analogen Auswahlwert (5) mithilfe des Auswahlsignals (3) zu erfassen und zu prüfen, ob dieser einem Wert entspricht, welcher einem Übergangsbereich (21-23) zugeordnet ist, und falls zutreffend, ein Signal durch ein Signalisierungsmittel (7) auszugeben.
Patent EP-3994579-A1 (EP)
Inventor: LECOINTE PIERRE
IPC: G06F9/54
Filed: 2020-06-29
Abstract: The invention relates to a distributed system (100) for managing a maintenance task of a motor vehicle and to a method for managing a maintenance task of a motor vehicle implemented by means of such a system.
Patent EP-4003817-A1 (EP)
Inventor: VIRY PATRICK
IPC: B62D27/02
Filed: 2020-07-16
Abstract: The invention relates to a rear region arrangement of a motor vehicle body structure with a tailgate-type rear flap, comprising an underframe subassembly (10) comprising a load floor (11) and two lateral floor extensions (12), two lateral contoured subassemblies (20) each comprising a rain channel lining (21) provided with a lower leg (21B), and also a rear panel subassembly (30) comprising a rear panel lining (32) provided with two lateral portions (32B), said underframe subassembly comprising two lateral base reinforcements (14), each welded to said load floor and also to a corresponding lateral floor extension, each of said lateral contoured subassemblies comprising a flap pillar reinforcement (24) welded to the lower leg of its rain channel lining, each lateral base reinforcement being fixed rigidly, after the assembly of said subassemblies, to a corresponding flap pillar reinforcement.
Patent EP-4003958-A1 (EP)
Title: Synthesis of bicyclic inhibitors of histone deacetylase
Inventor: FULLER NATHAN OLIVER
IPC: C07D487/04
Filed: 2020-07-23
Abstract: Provided herein are synthetic methods for the preparation of compounds having the Formula:(I) and (I') and salts thereof.
Patent EP-3998998-A1 (EP)
Inventor: SOFFIATTI RENZO
IPC: A61F2/38
Filed: 2020-07-17
Abstract: Prosthetic component provided with a stem (3), adapted to be implanted in use at a bone of a patient, such as for example a tibial and/or femoral component of a knee prosthesis or a femoral component of a hip prosthesis or a humeral component of a shoulder prosthesis, or a component of an elbow prosthesis, comprising a device (10) adapted to externally cover and/or to house at its interior at least the stem (3) of the prosthetic component (1), wherein the device (10) is in use placed between the prosthetic component and the bone of the patient, suitable to stably constrain in use the prosthetic component to the bone of the patient and to prevent the direct contact between prosthetic component and bone of the patient.
Patent EP-3932903-A1 (EP)
Inventor: IMAHORI TATSUSHI
IPC: B01J20/22
Filed: 2020-02-28
Abstract: A compound represented by Formula (1): each of L<sup>1</sup> and L<sup>2</sup> independently represents an alkyl group having from 1 to 20 carbon atoms, an alkoxy group having from 1 to 20 carbon atoms, NH2, NHR<sup>3</sup>, NR<sup>3</sup>R<sup>4</sup>, an ester group, a carboxy group, an amide group, a cyano group, a nitro group, a halogen atom, an acyl group, CF3, O(CH<sub>2</sub>)<sub>1</sub>OCH<sub>3</sub>, a carbamate group, or an aryl group. 1 represents 1 or 2. Each of R<sup>1</sup> and R<sup>2</sup> independently represents a divalent hydrocarbon group having from 1 to 10 carbon atoms, at least one hydrogen atom of the divalent hydrocarbon group is optionally substituted with an alkyl group, an aryl group, an ester group, a carboxy group, an amide group, a cyano group, a nitro group, a halogen atom, an acyl group, CF3, O(CH<sub>2</sub>)<sub>1</sub>OCH<sub>3</sub>, a carbamate group, or an alkoxy group, each of R<sup>3</sup> and R<sup>4</sup> independently represents an alkyl group, an aryl group, an acyl group, an ester group, an alkylsulfonyl group, or an arylsulfonyl group, each of R<sup>5</sup> and R<sup>6</sup> independently represents a hydrogen atom, an alkyl group having from 1 to 20 carbon atoms, or an aryl group, and n + m ≥ 1.
Patent EP-4035254-A1 (EP)
Inventor: MILOSAVLJEVIC MISA
IPC: H02K1/02
Filed: 2020-09-04
Abstract: The invention relates to a compression device comprising an electrical machine having a hybrid magnetisation rotor with a cylindrical permanent magnet (5) and a hollow shaft (7) made of a material with temporary or modulatable magnetisation.
Patent EP-4021596-A1 (EP)
Title: Techniques destinées à la compensation d'entrée de jeu vidéo, systèmes et procédés associés
Inventor: CHALLINOR RYAN WILLIAM
IPC: A63F13/497
Filed: 2020-08-25
Abstract: L'invention concerne des techniques permettant d'améliorer l'expérience utilisateur dans un jeu vidéo. Dans certains modes de réalisation, les techniques font intervenir un ou plusieurs instantanés du jeu vidéo au fil du temps pour ajuster une position du dispositif d'entrée de l'utilisateur dans le jeu vidéo. Par exemple, le dispositif d'entrée de l'utilisateur peut être une manette à suivi spatial dont la position est suivie dans le jeu vidéo. Une entrée utilisateur peut indiquer un bouton pressé sur la manette à suivi spatial (par exemple, le déclenchement d'un tir dans le jeu vidéo). Dans certains modes de réalisation, les techniques font intervenir ledit instantané du jeu vidéo qui capture des instants précédant l'entrée utilisateur pour ajuster une position du dispositif d'entrée utilisateur dans le jeu vidéo afin d'offrir une expérience utilisateur améliorée.
Patent EP-3936127-A1 (EP)
Inventor: NAKASHIMA YOSHIHIRO
IPC: A61P9/04
Filed: 2020-03-03
Abstract: The present invention aims to provide a preparation containing a compound of the formula [I] or a pharmaceutically acceptable salt thereof or a hydrate thereof having improved pharmacokinetics, and a manufacturing method thereof. The present invention relates to a solid dispersion containing (1) an amorphous compound represented by the following formula [I]:
     
or a pharmaceutically acceptable salt thereof or a hydrate thereof, and 
(2) one to four kinds of pharmaceutically acceptable polymers selected from the group consisting of hydroxypropylmethylcellulose acetate succinate, methylcellulose, hypromellose and polyvinyl alcohol, and a manufacturing method thereof.
Patent EP-3935082-A1 (EP)
Inventor: CHAN LAI LING SHARON
IPC: G01N33/53
Filed: 2020-03-06
Abstract: Methods of detecting the phosphorylation at Threonine 166 and/or Serine 189 of a Rubicon protein to identify a subject having a disease associated with Leucine-rich repeat kinase 2 (LRRK2) such as Parkinson's disease using an antibody. Also disclosed are methods of treating the same using inhibitors to block the interaction of LRRK2 with Threonine 166 and/or Serine 189 of the Rubicon protein.
Patent EP-4025496-A1 (EP)
Inventor: WARSOP CLYDE
IPC: B64C15/02
Filed: 2020-09-03
Abstract: A vehicle control system (110) for use with at least one fluidic control effector (102) for a vehicle, the vehicle control system (110) comprising a controller (110), wherein the controller is configured to: receive a vehicle control input indicating a demanded vehicle manoeuvre, wherein the input is further configured to receive condition data; determine a fluid mass-flow for the at least one fluid control effector based on the received vehicle control input and the condition data, wherein the relationship between the fluid mass- flow and the vehicle control input is substantially non-linear; and output data relating to the determined fluid mass-flow to effect the demanded vehicle manoeuvre, wherein the fluid mass-flow is determined to provide a substantially linear relationship between the vehicle control input and the effected demanded vehicle manoeuvre.
Patent EP-3942314-A1 (EP)
Inventor: JANUSZKO WIESLAW MARIUSZ
IPC: G01R31/60
Filed: 2020-03-18
Abstract: A method of identifying opposing ends of a cable within a cabling assembly having a plurality of cables. The method includes transmitting a signal to a first end of a cable of the plurality of cables, receiving the signal at a second end of the cable of the plurality of cables, transmitting an output signal from a connector operably coupled to the second end of the cable of the plurality of cables to a processor. The connector is one of a plurality of connectors. The method additionally includes identifying using an indicator device the connector of the plurality of connectors that is operably coupled to the second end of the cable.
Patent EP-3947718-A1 (EP)
Inventor: SEKEDAT MATTHEW
IPC: C12Q1/68
Filed: 2020-04-02
Abstract: Compositions and methods, systems, and kits for detecting and quantifying variations in numbers of molecules, particularly variations in gene dosage, e.g, due to gene duplication, or to variations from the normal euploid complement of chromosomes, e.g., trisomy of one or more chromosomes that are normally found in diploid pairs, without digital sequencing.
Patent EP-4045175-A1 (EP)
Inventor: CHIFFEY ANDREW FRANCIS
IPC: B01D53/94
Filed: 2020-10-13
Abstract: A compression ignition internal combustion engine for a heavy-duty diesel vehicle comprising an exhaust system comprising a composite oxidation catalyst (12, 42) upstream of a soot filter substrate (44, 50), the composite oxidation catalyst comprising: a substrate (5) having a length L and extending axially between an inlet end (I) and an outlet end (O) and two catalyst washcoat zones (1, 2), wherein the first catalyst washcoat zone (1) having a length LI wherein L1<L, is defined at one end by the inlet end (I) and at a second end by a first end (15) of the second catalyst washcoat zone (2) having a length L2, wherein L2<L, wherein the second catalyst washcoat zone (2) is defined at a second end thereof by the outlet end (O), and wherein the first catalyst washcoat zone (1) comprises a first refractory metal oxide support material and supported thereon both platinum and palladium at a Pt/Pd weight ratio of <1; and the second catalyst washcoat zone (2) comprises a second refractory metal oxide support material and one or more platinum group metal components supported thereon; and a washcoat overlayer (G) extending axially from the inlet end (I) comprising a particulate metal oxide having a loading of >48.8 g/l, wherein a total platinum group metal loading in the first catalyst washcoat zone (1) is greater than a total platinum group metal loading in the second catalyst washcoat zone (2) and wherein the first catalyst washcoat zone (1) comprises one or more alkaline earth metal components supported on the first refractory metal oxide support material.
Patent EP-3955871-A1 (EP)
Inventor: JUNGER JOHANNES
IPC: A61F9/008
Filed: 2020-04-20
Abstract: The invention provides an excimer laser system including a means for calibrating laser output to compensate for increased variation in laser optical fibers.
Patent EP-4066457-A1 (EP)
Inventor: GLICK MORDECHAI
IPC: H04W4/10
Filed: 2020-09-30
Abstract: A device, system and method for emergency audio transmission is provided. A server receives, over a broadband network, a request to make an emergency audio transmission to a talk group. The request is received from a first push-to-talk (PTT) device communicatively connected with the talk group over a narrow band network at which a second PTT device of the talk group has floor control. In response to granting the request, the server receives, from the first PTT device, an audio transmission over the broadband network, and transmits the audio transmission to the talk group via the broadband network.
Patent EP-4051614-A1 (EP)
Inventor: BÜTLER ERICH
IPC: B66B7/02
Filed: 2020-10-27
Abstract: Die vorliegende Erfindung bezieht sich auf eine Aufzuganlage (100), aufweisend: - ein Schienensystem (102), - zumindest eine Schachttürbaugruppe (110) an jeder einer Mehrzahl von Etagen (108) eines Gebäudes, wobei das Schienensystem (102) aufweist: - zumindest eine Führungsschiene (104), welche sich entlang der Mehrzahl von Etagen (108) erstreckt und welche zum Führen einer vertikal beweglichen Komponente der Aufzuganlage (100) konfiguriert ist, wobei die Führungsschiene (104) elektrisch leitfähig ist; - zumindest eine Konsole (106) an jeder der Etagen (108), wobei insbesondere jede Konsole (106) die Führungsschiene (104) an einer Wand des Gebäudes verankert, wobei insbesondere jede der Konsolen (106) elektrisch leitfähig ist; wobei in dem Schienensystem (102) die Führungsschiene (104) mit insbesondere jeder der Konsolen (106) elektrisch leitfähig verbunden ist; wobei jede Schachttürbaugruppe (110) eine verlagerbare Schachttür zum öffenbaren Verschließen einer Schachtöffnung der Etage (108) sowie eine eigene Steuereinrichtung (112) und/oder Antriebseinrichtung (112) zum Verlagern der Schachttür aufweist; wobei die Steuereinrichtung (112) und/oder Antriebseinrichtung (112) über zwei elektrisch leitfähige Pfade (122, 124) mit elektrischer Energie zu versorgen ist; wobei ein erster der elektrisch leitfähigen Pfade (122, 124) über zumindest Teile des Schienensystems (102) ausgebildet ist.
Patent EP-4038030-A1 (EP)
Title: Panneau de refroidissement pour un dispositif de fusion
Inventor: RASHLEY SHANE T
IPC: C03B5/235
Filed: 2020-09-29
Abstract: L'invention concerne un panneau de refroidissement (12, 212, 312, 412) pour un dispositif de fusion (10) et un procédé de fabrication du panneau de refroidissement (12, 212, 312, 412). En particulier, le panneau de refroidissement (12, 212, 312, 412) peut comprendre une première (20, 120, 220, 420) et une seconde (22, 122, 222, 422) paroi externe et une pluralité de parois latérales (34, 36, 38, 40, 134, 136, 138, 140, 334, 336, 338, 340, 434, 436, 438, 440) reliées aux parois externes de façon à définir un espace intérieur (62, 462). Une pluralité de déflecteurs (24, 424) est disposée dans l'espace intérieur (62, 462), des saillies (48, 52) dans les déflecteurs (24, 424) s'ajustant dans des ouvertures respectives (28, 44) ménagées dans les parois externes (20, 22, 120, 122, 220, 222, 420, 422) et pouvant être raccordées depuis l'extérieur du panneau de refroidissement (12, 212, 312, 412). Le panneau de refroidissement (12, 212, 312, 412) peut être formé par soudage et/ou fabrication additive.
Patent EP-4042280-A1 (EP)
Inventor: LIBBY MARK
IPC: G06F9/52
Filed: 2020-10-09
Abstract: A network function is implemented using cloud native architecture. The network function utilizes one or more loosely coupled and independently deployable microservice instances to perform services. To retain state between independent transactions, a microservice instance takes a soft lock on state data in an external database. The soft lock makes the state data unavailable except to the microservice instance. After the microservice instance completes the transaction, the microservice instance clears the lock so that the state data is available for use by other microservices.
Patent EP-4058502-A1 (EP)
Title: Procédé de polymérisation de lactide à l'aide d'une formulation de catalyseur liquide
Inventor: GOBIUS DU SART GERRIT
IPC: C08G63/82
Filed: 2020-11-13
Abstract: La présente invention concerne un procédé de polymérisation de lactide comprenant les étapes consistant à a) préparer une formulation de catalyseur liquide comprenant un catalyseur, un initiateur et du lactide, et b) mettre en contact la formulation de catalyseur liquide préparée à l'étape a) avec du lactide, et polymériser ledit lactide en présence de ladite formulation de catalyseur liquide pour former du polylactide. L'invention concerne en outre une formulation de catalyseur liquide et son utilisation pour la polymérisation de lactide.
Patent EP-4046250-A1 (EP)
Title: Tower, particularly for a high-voltage overhead electric transmission line, equipped with switchgear unit and related protection, command and control system
Inventor: DI BARTOLOMEO EVARISTO
IPC: H02B5/06
Filed: 2020-10-14
Abstract: A tower is described for an overhead electric line, particularly for a high-voltage electric transmission line. The tower has a predetermined shape that defines an internal volume of the tower, and carries a first tension side of a first line section (24) and a second tension side of a second line section (26). The first tension side and the second tension side comprise respective pluralities of first and second tension terminals, each associated with a respective phase of the high-voltage overhead electric transmission line. The tower is arranged to support, within the internal volume, a switchgear unit (17) connected to a first end to the first line section (24) and to a second end to the second line section (26). The switchgear unit (17) is able to modify the configuration of the grid, interrupting and restoring the electrical continuity in pre-established points, to interrupt the nominal and fault currents, and to carry out the safety operations, through grounding, of sections of the line. The switchgear unit (17) includes a plurality of switchgear unit poles (17A, 17B, 17C), each associated with a respective phase of the high-voltage overhead electric transmission line (1). Each of the switchgear unit poles (17A, 17B, 17C) comprises a line circuit breaker (50) and at least one line disconnector (52).