baber/WOPTO huggingface dataset:
Patent PT-765150-E (PT)
Inventor: GOOSSENS FRANCIS
IPC: A61J3/07
Filed: 1995-06-13
Abstract: A process and an apparatus for producing closed sealed capsules are disclosed. The capsules contain releasable substances packaged in at least one cavity inside the capsules which are formed of two or more joined sealed parts of substantially organic, film forming material. The process comprises the steps of: (a) providing a first part of the capsule having a first contact zone; (b) filling the first part of the capsule with the substances to be packaged; (c) providing at least a second part of the capsule having a second contact zone; (d) applying binding means to at least one of the contact zones; (e) joining the parts of the capsule, so that the contact zones come into contact via the binding means; and (f) pressing the joined parts of the capsule together with a predetermined force so that portions of opposite contact zones are kept in pressed contact for a predetermined period of time to obtain the closed sealed capsule. Also disclosed is an apparatus for carrying out this process, preferably including a channel (31) having a first opening (56) and a second opening (43) spaced apart from the first opening (56), such that joined parts (21, 22) of the capsules (20) are insertable into the channel (31) through the first opening (56), are guidable along the channel (56) and are ejectable from the channel (31) through the second opening (43), whereby the inserted parts (21, 22) of the capsules (20) form a row such that successive pairs of joined parts (21, 22) stay in direct contact with one another.
Patent PT-793659-E (PT)
Inventor: LEANNA M ROBERT
IPC: C07D277/24
Filed: 1995-11-15
Abstract: A process for the preparation of 5-hydroxymethylthiazole comprises reacting a compound of the formula,   <IMAGE>   with a carboxylic acid salt (optimally in the presence of a quaternary ammonium salt) and hydrolyzing the resulting ester. Subsequent dechlorination gives 5-hydroxymethylthiazole.
Patent PT-745369-E (PT)
Inventor: MICHELER CLEMENS
IPC: A61J1/00
Filed: 1996-05-30
Abstract: A container 10 for a liquid medicament suspension, e.g. an insulin crystal suspension, has a tube 11 with a sealing piston 13, a cap 16, and a mixing element 20 which moves along the tube 11 to assist mixing the suspension. The element 20 is guided by the inner surface of the tube 11 and has restricted lateral movement but is free to move axially, for example, by tilting or end to end inversion of the container. Flow passages such as apertures and peripheral recesses are provided in the mixing element which can serve to promote turbulent flow. The containers are particularly suited for use as multi-dose cartridges for pen-like injection devices or for portable infusion devices which have piston- operating mechanisms to co-operate with the container piston. <IMAGE>
Patent PT-920607-E (PT)
Inventor: OLSSON BERT-AKE
IPC: G01F11/10
Filed: 1997-08-14
Abstract: A method and device are disclosed for metering a predetermined amount of a particulate substance in a reliable and exact manner. The claimed invention avoids crushing or packing the material to be metered, and can be utilized with fine particulate substances with poor flow properties such as agglomerates as well as with coarser granulates. The substance to be metered is gravity-fed by a tumbling reservoir and inlet through an unbroken and uninterrupted inflow path which comprises two parts, one which is coaxial with the rotational axis, and a second which is inclined relative to the rotational axis. After passage through the inflow path, the substance enters the metering chamber which accurately and uniformly measures the desired quantity of substance, which then exits through the outflow path. The design of the device prevents inaccurate metering through overfilling or premature emptying of the metering chamber.
Patent PT-887418-E (PT)
Inventor: SAUER THOMAS
IPC: C12N9/96
Filed: 1993-12-24
Abstract: Cell contents are obtained from cells in vivo by transforming cells from a first state into a second state by subjecting them to stress conditions such that they are forced either to release cell contents into their environment or to synthesize cell contents in order to adapt themselves to the conditions of the second state; the procedure being repeated at least twice reverse stress. S,S-Alpha-amino-beta-hydroxyectoin of formula (I) is also claimed.
Patent PT-1034260-E (PT)
Inventor: ZHANG YUNCHANG
IPC: C12N1/21
Filed: 1998-12-07
Abstract: The invention refers to a novel method for cloning DNA molecules using a homologous recombination mechanism between at least two DNA molecules comprising:   a) providing a host cell capable of performing homologous recombination, b) contacting in said host cell a first DNA molecule which is capable of being replicated in said host cell with a second DNA molecule comprising at least two regions of sequence homology to regions on the first DNA molecule, under conditions which favour homologous recombination between said first and second DNA molecules and c) selecting a host cell in which homologous recombination between said first and second DNA molecules has occurred.
Patent PT-1037629-E (PT)
Inventor: WOUTERS WALTER BOUDEWIJN LEOPO
IPC: A61K31/00
Filed: 1998-12-12
Abstract: The present invention is concerned with the use of a tocopherol for the manufacture of a medicament for avoiding, alleviating, suppressing or overcoming the adverse side-effects of therapy with a retinoic acid metabolism blocking agent. The present invention is also concerned with the combination of 4-(heteroaryl-methyl)anilines with vitamin E and its use as a medicine.
Patent PT-1047446-E (PT)
Inventor: AURELIAN LAURE
IPC: A61P31/22
Filed: 1999-01-15
Abstract: The present invention discloses a new immunogenic composition for Herpes Simplex comprising a whole live HSV-2 virus having the oncogene deleted. Methods of using the vaccine composition are also included.
Patent PT-1075462-E (PT)
Inventor: INCANDELA SALVATORE
IPC: C07C231/02
Filed: 1999-04-26
Abstract: A process for the preparation of S- N,N'- bis[2- hydroxy-1- (hydroxymethyl) ethyl]- 5-[(2- hydroxy-1- oxopropyl)amino]- 2,4,6- triiodo- 1,3- benzenedicarboxamide, comprising the formation of S- N,N'- bis[2- hydroxy- 1(hydroxymethyl)ethyl]- 5-[(2- (acetyloxy)- 1-oxopropyl)amino]- 2,4,6- triiodo-1,3- benzenedicarboxamide starting from S-(-)- 5-[[2- (acetyloxy)- 1-oxopropyl]amino]- 2,4,6- triiodo- 1,3- benzenedicarboxylic acid dichloride and 2- a mino-1,3- propanediol in a solvent, characterized in that the solvent is selected from the group consisting of: lower alcohols, monoalkyl ether glycols and straight or branched cyclic alkyl ethers.
Patent FR-84-F (FR)
Abstract: SELON L'INVENTION, ON DISPOSE ENTRE DEUX CYLINDRES DE LA ZONE DE PRECARDAGE UN PROFIL SPECIAL DE CONSTITUTION DIEDRIQUE ET DE FORME CONCAVE INCURVEE EN CORRESPONDANCE ET AU VOISINAGE DE LA PERIPHERIE DE CES CYLINDRES. LEDIT PROFIL PERMET L'ELIMINATION DES FIBRES COURTES ET DES IMPURETES LORS DU PASSAGE DES FIBRES DU PREMIER AU SECOND CYLINDRE, AVEC L'AIDE DU FLUX D'AIR ENTRAINE PAR LA ROTATION DU SECOND CYLINDRE.
Patent IE-820191-L (IE)
Title: Quaternary piperidinium halides
IPC: C07D211/26
Filed: 1982-01-28
Abstract: 2-[2-[2-[(4-Methoxybenzoyl)amino]phenyl]ethyl]-1-methyl-1-alkylpiperid inium halides and 2-[2-[2-[(4-methoxybenzoyl)amino]phenyl]ethyl]-1-methyl-1-benzylpiperi dinium halides are antiarrhythmic agents having reduced toxicity relative to the corresponding piperidine compound.
[US4321386A]
Patent IE-880273-L (IE)
Title: Dextro-rotatory enantiomer of methyl alpha-5¹(4,5,6,7-tetrahydro (3,2-c) thieno pyridyl)¹(2-chlorophenyl)-acetate, a process for its preparation and¹the pharmaceutical compositions containing it
IPC: C07B57/00
Filed: 1988-02-01
Abstract: The present invention relates to the dextro-rotatory enantiomer of Formula <IMAGE> and its pharmaceutically acceptable salts with platelet aggregation inhibiting activity. The invention also relates to a process for the preparation of this compound starting from the racemate and the pharmaceutical compositions containing it.
[US4847265A]
Patent IE-31993-L (IE)
Title: Building frame
IPC: E04B1/21
Filed: 1968-03-22
Abstract: 1,266,174. Concrete frame structures. H. M. CLYNE and P. J. FAHERTY. 20 March, 1969 [22 March, 1968], No. 14578/69. Heading E1W. In an interconnecting reinforced concrete beam-column arrangement, a steel shoe 7 embedded in and welded to the longitudinal reinforcing bars of a beam 2 fits over a projecting steel joist section 5 of a column 1, the shoe being of inverted channel section and the joist of U-shaped or hallow section. To ensure predetermined alignment, interfitting steel members 6, 8 are also provided on the column and beam respectively. The beams of such a framework are bridged by floor members (3, Fig. 10, not shown).
[GB1266174A]
Patent IE-33777-L (IE)
Title: Aminophthalazines
IPC: C07D401/04
Filed: 1970-04-08
Abstract: 1293565 Phthalazine derivatives ASPRONICHOLAS Ltd 30 April. 1970 [3 May 1969] 22679/69 Heading C2C The invention comprises compounds of formula and their acid addition salts and quaternary ammonium derivatives, wherein R is aryl or aralkyl; R 1 is cycloalkyl, cycloalkylalkyl, heterocyclyl or heterocyclylalkyl, and R 2 is the same or H, or NR 1 R 2 is a 5-7-membered heterocyclic ring containing N, O or S as heteroatoms; and R 3 , R 4 are each H or a substituent as defined in the Specification. These compounds are prepared by reacting with HNR 1 R 2 an appropriately substituted phthalazine having, instead of NR 1 R 2 in the desired product, halogen, alkylthio or arylthio, or the corresponding sulphoxide or sulphone groups, followed, if necessary, by conversion by known methods of one substituent group to another. Pharmaceutical and veterinary compositions for oral, parenteral or rectal administration, comprise compounds of the above formula, which have anti-inflammatory (in particular antirheumatic) activity, and in some cases immunosuppressive activity.
[GB1293565A]
Patent IE-900625-L (IE)
Title: Process for producing rippled snack chips
IPC: A23L1/164
Filed: 1990-02-21
Abstract: Corrugated snack food pieces are fabricated from a dough directed through a pair of mated corrugated sheeting rolls. The dough is impressed with the corrugated pattern of the sheeting rolls and subsequently cut into individual snack food pieces. The dough is fed directly into the sheeting rolls so that no prior memory is imparted to the dough sheet prior to receiving its corrugated shape. The corrugated sheeting rolls may be scored transverse to the corrugations to provide transverse webs of dough between adjacent corrugations.
[EP0387606A2]
Patent IE-36369-L (IE)
Title: Gate valve for a foundry ladle
IPC: B22D41/28
Filed: 1972-05-23
Abstract: 1399011 Gate valves for foundry ladles USS ENGS & CONSULTANTS Inc 31 May 1972 [7 June 1971] 25545/72 Heading F4B A bottom pour valve for a foundry ladle V comprises a stationary plate 9 fitting in a recess in a valve mounting plate 66 and co-operating with a sliding plate 12 movable in a frame 13 and pressed against the plate 9 by a number of spring loaded pressure pads 15 arranged round the outlet nozzle 22 of the valve plate 12 so as to provide sealing pressure over a zone surrounding the outlet of the vessel. The spring pads 15 are mounted within a carriage 14 sliding in the frame 13 and are cooled by air from a passage 17 extending through the hydraulic operating cylinder 16 to chambers 75. The upper face of the stationary plate 9 has a groove co-operating with the end of an outer sleeve 6 surrounding the ladle nozzle to prevent leakage, and the hydraulic piston arrangement is detachable from the valve carriage. A lower fixed spatter shield 24 fixed to the frame 13, and a spatter shield 25 fixed to the valve 12 and sliding with it protect the underside of the valve. The valve assembly may be secured to the ladle by a hinge toggle arrangement 34 and a latch toggle arrangement 33, so that the frame 13 and carriage 14 can be swung away from the ladle to allow replacement or reversal of the stationary plate 9, and replacement of the sliding plate 12, Figs. 4 and 7. In a modification. Fig. 15, the sliding plate 12 moves between the stationary plate 9 and the top 48 of an extended nozzle 49, the spring pads acting on the top 49 of the nozzle.
[GB1399011A]
Patent FI-852310-L (FI)
Inventor: SKAOLLEN BENGT
IPC: G01N15/08
Filed: 1985-06-10
Abstract: Arrangement and method for drainage determination by permeability measurements. The arrangement is designed to take a sample from a suspension, especially a fiber suspension, which, for example, flows in a pipeline 2, said arrangement containing a measurement cylinder housing 4 connected to the pipeline 2 and containing a sampling flask 5, which can be introduced into the pipeline 2 and has a through-hole forming a sample chamber 9 to take a pulp sample. The housing 4 is connected to a dilution and mixing chamber 35 containing an agitator or mixing device 36, in which the lower end of the chamber 35 is connected to a screen plate 22 containing end piece 26. In the method according to the invention a measurement is first carried out on an entire pulp sample, whereupon its fine material fraction is separated from the sample by a washing process in the mixing chamber 35 and measurement of the fiber fraction in the pulp fraction is then carried out, for which purpose the permeability of the pulp bed formed on the screen plate 22 is measured during one or more pressure drops, possibly with intermediate knocking by means of the mixing device 36 and reformation of the pulp bed. <IMAGE>
Patent IE-901063-L (IE)
Title: Polycyclic amines useful as cerebrovascular agents
IPC: C07C215/44
Filed: 1990-03-22
Abstract: A novel series of polycyclic amine derivatives, of formula I <CHEM> methods of making the compounds, novel intermediates, compositions containing them, and pharmaceutical compositions useful in the treatment and prevention of cerebrovascular disorders and useful as anesthetics or analgesics.
[EP0388977A2]
Patent IE-781283-L (IE)
Title: Sulphonamide-containing pharmaceutical composition
IPC: A61P31/04
Filed: 1978-06-27
Abstract: This invention relates to the preparation of an aqueous solution tolerated well for administration with intravenous way containing a sulphonamide and 2,4-diamino-5- (3 ', 4 ', 5 ' - trimethoxybenzyl) - pyrimidin. [FR2396550A1]
Patent IE-37966-L (IE)
Title: Cross-linked elastomer composition; solid golf ball.
IPC: A63B37/04
Filed: 1973-08-02
Abstract: Solid golf balls, characterized by high initial velocity as well as outstanding retention of properties on continued hitting, are made from a blend of a resilient elastomer (e.g., cis-polybutadiene) and zinc oxide-methacrylic acid reaction product, the composition being cured with a free-radical cross-linking agent such as peroxide.
[US4266772A]
Patent IE-32779-L (IE)
Title: Penicillin/sulphonamide compositions
IPC: H01F27/14
Filed: 1968-11-22
Abstract: 1,249,661. Antibiotic-sulphonamide compositions. BRISTOL-MYERS CO. 10 Dec., 1968 [15 Dec., 1967], No. 58643/68. Heading A5B. Pharmaceutical compositions in forms suitable for oral, rectal, parenteral and topical administration comprise ampicillin or hetacillin (0.1 to 0.5 parts) and sulphisoxazole (1 part by weight).
[GB1249661A]
Patent IE-821429-L (IE)
Title: Aqueous dispersion of film-forming polymer
IPC: C09D201/00
Filed: 1982-06-15
Abstract: Preparation of stable aqueous dispersions of particles of film-forming polymer, the particles comprising at least one pre-formed polymer and at least one polymer formed in situ ("multi-polymer particles"). The inadequate stability exhibited by many previously known film-forming systems based on multi-polymer particles, especially in the presence of co-solvents, may be overcome by preparing the particles in the presence of a stabilising compound which is an amphipathic compound with a hydrophilic-lipophilic balance (HLB) value of at least 8 and whose lipophilic portion comprises at least one ethylenic double bond. The dispersions of this invention are useful as the film-forming components of coating compositions.
[WO8300151A1]
Patent IE-45173-L (IE)
Title: Collection of oyster-brood
IPC: A01K61/54
Filed: 1977-07-26
Abstract: A method and a device for collecting oyster broods utilizing a collecting grill with the following features: (a) a rectangular frame onto which are attached a series of parallel bars, (b) a series of ribs encircling each bar, spaced the length of one oyster apart, and which rise above the bars, a height slightly less than the height of the lime coating, which forms on the grill. A number of sections are formed by the intersection of the bars and ribs; each section is large enough for one oyster. The oysters attach to the lime coating on each space. When a sudden force is applied to the grill, the coating and the oysters detach from the collector, without the oysters coming into contact with each other.
[US4177759A]
Patent IE-841832-L (IE)
Title: ANTITUMOR AGENT FR 900216u
IPC: C12P1/02
Filed: 1984-07-16
Abstract: FR-900216 substance obtainable by cultivating ATCC 20577 in a nutrient medium containing sources of assimilable carbon and nitrogen under aerobic conditions and recovering it from the culture broth and its use as an active therapeutic substance especially for treatment of tumor. The invention covers also a pharmaceutical antitumor composition comprising FR-900216 substance in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient. 
[EP0132772A2]
Patent IE-781889-L (IE)
Title: Dyed impregnated substrate
IPC: D06M23/00
Filed: 1978-09-19
Abstract: The invention is a method of indicating the presence of an impregnant, e.g. an antimicrobial composition, in cloth to provide visual evidence of the continuing activity of the impregnant. The antimicrobial composition in the cloth is activated on contact with a liquid such as water and is ionically bonded to the cloth. Small portions of the impregnated cloth are dyed with an indicator dye which bonds preferentially to the antimicrobial composition so that when the antimicrobial composition is exhausted, the dye will disappear from the cloth. The dye is preferably applied to the cloth in stripes.
[US4311479A]
Patent IE-891963-L (IE)
Title: Method of treating cachexia and certain new compounds for¹use in this method
IPC: A61K31/535
Filed: 1989-06-16
Abstract: Compounds of formula (I): <CHEM>  [in which:  Y represents a group of formula <CHEM> the dotted line is a double or single bond; R<1> is hydrogen, alkyl or aryl; R<2> is hydrogen or halogen; R<3> is alkyl or cycloalkyl; R<4> is hydrogen, alkyl, hydroxy or halogen; R<5> is hydrogen, alkyl, hydroxy, oxygen or halogen; and R<6> is hydrogen, optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, or aralkyl;] and pharmaceutically acceptable salts thereof are valuable in the treatment, alleviation and prophylaxis of cachexia. Certain of these compounds are novel.
Patent IE-862267-L (IE)
Title: Drug-polymer matrix
IPC: A61K9/22
Filed: 1986-08-25
Abstract: This invention relates to drug-polymer matrix compositions comprising an active ingredient having an amino or amido group and a pharmaceutically acceptable copolymer having a plurality of carboxylic acid and ester groups wherein the matrix dissociates in a media having a pH of less than 4, thereby releasing the active ingredient into the media.
Patent IE-822590-L (IE)
Title: Making diamond compacts
IPC: C01B31/06
Filed: 1982-10-28
Abstract: An improved process for sintering fine diamond is disclosed wherein such diamond is coated with non-diamond carbon (e.g. pyrolytic carbon) at a level of 1 to 10 weight per cent of the diamond mass. Greatly improved process yields are obtained through this technique.
Patent NO-781051-L (NO)
Title: Kinazolinderivater.
Inventor: KIERSTEAD RICHARD WIGHTMAN
IPC: A61K31/505
Filed: 1978-03-22
Abstract: Kinazolinderivater.
Patent NO-830840-L (NO)
Inventor: PETIOT ROGER LOUIS
IPC: A47G19/00
Filed: 1983-03-10
Abstract: 1. A receptacle (1) usable in cooking for receiving a culinary preparation to be consumed and having, outwardly, substantially the general shape of a snail shell, said snail shell having an opening (5) at its upper part (when considered in the use position of the receptacle), characterized in that said opening (5) has an outline identical to those virtually made by the intersection of a real snail shell and the plane definited by the edge of the real opening of a real shell.
Patent NO-853573-L (NO)
Inventor: AGBACK KARL HUBERT
IPC: C07C235/42
Filed: 1985-09-12
Abstract: A compound having a potentially inhibitory effect on 15-hydroxy-prostaglandin dehydrognase (PGDH) and having the formulain whichR<sub>1</sub> and R<sub>2</sub> are hydrogen or lower alkyl;R<sub>3</sub> is hydrogen, lower alkyl or substituted or unsubstituted phenyl;R<sub>4</sub>, R<sub>5</sub> and R<sub>e</sub> are hydrogen, halogen, lower alkyl, lower alkoxy, cyano, carboxy or nitro; at least one of the groups R<sub>4</sub> to R<sub>6</sub> being hydrogen;R<sub>7</sub> to R<sub>11</sub> are hydrogen, halogen, cyano, lower alkyl, trifluoromethyl, lower alkoxy, hydroxy, lower acyl, lower alkoxycarbonyl, N,N,-diloweralkyl-aminocarbonyl or N,N-loweralkylene-aminocarbonyl; and R<sub>8</sub> to R<sub>10</sub> may in addition be carboxy; at least two of R<sub>7 </sub>to R<sub>11</sub> always being hydrogen; and -A- is -CO-, -CH<sub>2</sub>-CO-, -CH=CH-, -CH=CH-<sub>CO</sub>- or corresponding groups in which a hydrogen atom is replaced by a lower alkyl group.The invention comprises also lactones of those compounds in which R<sub>1</sub> is hydrogen, and salts of those compounds which contain at least one carboxy group.
Patent NO-854617-L (NO)
Inventor: MILLER MICHAEL ROBERT
IPC: H04L25/14
Filed: 1985-11-19
Abstract: @ A broadband digital transmission system enables high bit rate data stream to be transmissed over low bit rate telephone networks.A high bit rate stream of data from a source 2 is distributed by a distributor 4 into six separate streams to provide six low bit rate streams of data.A call unbit 6 establishes six channel communication with a receiver 20 and the six data streams are fed in parallel along the six channels. A reassembler 34 receives the six low bit rate streams and reconstructs them to produce the original high bit rate stream of data.
Patent NO-871399-L (NO)
Inventor: NILSSON LARS
IPC: B60K/
Filed: 1987-04-03
Abstract: The invention concerns a power take-off apparatus for a tractor. The power take-off apparatus comprises a power take-off (PTO) shaft (1) on which have been disposed two gear wheels (4,5) arranged to be freely rotatable and which operate independent of the speed of rotation of the tractor's traction wheels. The first gear wheel (4) has been arranged to rotate within a high speed range and the second gear wheel (5), within a low speed range. The PTO apparatus furthermore comprises two shaft pins (2,3) alternatively attachable to the PTO shaft (1), of which the first shaft pin (2) is intended for the high speed range and the second shaft pin (3), for the low speed range. When said second shaft pin (3) is attached to the PTO shaft (1), the shift sleeve (12) can be optionally coupled with said second gear wheel (5), but it is prevented from becoming coupled with said first gear wheel (4). When said first shaft pin (2) is connected to the PTO shaft (1), the shift sleeve (12) can be optionally coupled with the first or second gear wheel (4 or 5). On the PTO shaft (1) has furthermore been disposed a third gear wheel (25) arranged to be freely rotatable and arranged to operate at a speed dependent on the speed of rotation of the tractor's traction wheels. The shift sleeve (12) can be optionally coupled with said third gear wheel (25) independent of which one of the shaft pins (2 or 3) has been attached to the PTO shaft (1).