baber/WOPTO huggingface dataset:
Patent AT-E251669-T1 (AT)
Inventor: BAUER S CHRISTOPHER
IPC: C12N15/09
Filed: 1993-11-22
Granted: 2003-10-15
Abstract: The present invention relates to recombinant human interleukin-3 (hIL-3) variant or mutant proteins (muteins). These hIL-3 muteins contain one or more amino acid substitutions and may also have amino acid deletions at both the N- and C- termini. The invention also relates to pharmaceutical compositions containing the hIL-3 muteins and methods for using them. Additionally, the present invention relates to recombinant expression vectors comprising nucleotide sequences encoding the hIL-3 muteins, related microbial expression systems, and processes for making the hIL-3 muteins using the microbial expression systems. <??>Included in the present invention are deletion mutants of hIL-3 in which from 1 to 14 amino acids have been deleted from the N-terminus, and from 1 to 15 amino acids (corresponding to residues 119 to 133) have been deleted from the C-terminus, and which also contain one to three amino acid substitutions in the polypeptide. These hIL-3 mutant polypeptides may have biological activities similar to or better than hIL-3 and, in some cases, may also have an improved side effect profile.
Patent AT-E168779-T1 (AT)
Inventor: NASER WERNER
IPC: G01N33/53
Filed: 1994-01-21
Granted: 1998-08-15
Abstract: An immunoassay is disclosed for detecting collagen or collagen fragments in a sample by using an antibody that recognises a synthetic linear peptide corresponding to a sequence of non-helical C or N terminal area of collagen, said sample being preferably denatured.
Patent AT-E183919-T1 (AT)
Inventor: HENRY RICHARD A
IPC: A61K9/127
Filed: 1994-03-28
Granted: 1999-09-15
Abstract: The composition of the present invention combines the local anaesthetic lidocaine in free base form and the non-CFC aerosol propellant HFC-134a (1,1,1,2-tetrafluoroethane; CF3CH2F) or HFC-227 (1,1,1,2,3,3,3-Heptafluoropropane; CF3CHFCF3), or a combination thereof, thus incorporating previously-unattainable amounts of the lidocaine free base in solution in a non-CFC aerosol propellant. This particular form of relatively-concentrated cosolvent-free anaesthetic permits improved inhalation delivery to the airway and lung, and topical airway local anaesthesia is thus readily provided. A method in accordance with the invention provides for release of the anaesthetic in aerosolized form of selected dosage from a canister containing the pressurized local anaesthetic composition into a patient's respiratory system directly or by way of an airway.
Patent AT-E163461-T1 (AT)
Inventor: MAEKELAE JAAKKO
IPC: F04C2/344
Filed: 1994-07-01
Granted: 1998-03-15
Abstract: PCT No. PCT/FI94/00306 Sec. 371 Date Jan. 16, 1996 Sec. 102(e) Date Jan. 16, 1996 PCT Filed Jul. 1, 1994 PCT Pub. No. WO95/02762 PCT Pub. Date Jan. 26, 1995A rotator includes an axle and an associated rotor component having lamellar vanes. A case component surrounds the rotor component. Chambers arranged symmetrically in relation to the axle are disposed between the lamellar vanes. These chambers are pressurized by oil fed through feed and outlet openings connected to the chambers. Bearing members are arranged in an axial direction on both sides of the rotor component. A conical bearing carries the axial rotor load and is formed by a conical arrangement of juxtaposed surfaces defined by the case and axle. The case includes channels leading from the chambers to the conical surfaces for communicating pressurized oil thereamong. The conical arrangement includes spaced gaskets. Oil pressure applied between the conical surfaces raises the axle off the case. In the absence of oil pressure, the conical surfaces lock as a result of friction between the case and axle.
Patent AT-E281470-T1 (AT)
Inventor: SCHILLING JAMES W JR
IPC: A61K38/55
Filed: 1990-06-04
Granted: 2004-11-15
Abstract: An analog of human amyloid plaque core protein protease inhibitor wherein the amino acid corresponding to arginine at position 13 in the sequence <MATH> is substituted with an aromatic amino acid, said analog exhibiting chymotrypsin inhibitory activity or is substituted with a neutral hydrophobic amino acid, said analog exhibiting human elastase inhibitory activity and method of producing them. Use of the protease inhibitor in the manufacture of a medicament for use in treating acute pancreatitis and method of recovering purified protease inhibitor.
Patent AT-E162671-T1 (AT)
Inventor: WEHBERG JOSEF DIPL ING
IPC: H02P6/22
Filed: 1995-05-05
Granted: 1998-02-15
Abstract: The braking system involves a polyphase synchronous motor (10) with stator windings (12, 14, 16) connected to a DC system through switching devices (20, 22, 24) controlled by commutating equipment (29). The voltages (U, V, W) induced in the winding during reverse rotation are compared with a threshold value (Us), and the result used by the commutator to regulate the rotor angle (w). Position signals from the rotor (34) are used to control the switching devices connected between the stator windings and the operating voltage (UB). Commutation circuitry and conditions are identical in the case of forward and reverse motor rotation. <IMAGE>
Patent AT-E217884-T1 (AT)
Inventor: PETTIT GEORGE R
IPC: A61K38/00
Filed: 1995-07-21
Granted: 2002-06-15
Abstract: Herein disclosed are several pentapeptide methyl ester derivatives of dolastatin 10, using both naturally occurring and modified amino acids. The selected modified amino acids are constituents of dolastatin 10 which is a structurally distinct peptide with excellent in vitro and in vivo antineoplastic activity. The structures of these compounds are as shown below: <MATH>       10a) R1 = i-Pr ; R = -NH(Me)2 ; R2 = -CH2CH2CH2NH-cbz   10b) R1 = i-Pr ; R = -NH (Me)2 ; <CHEM>     11a) R1 = - (CH2)4NH-cbz ; R = -NH (cbz) ; <CHEM>     11b) <CHEM>  R = -NH(cbz) ; R2 = -CH2CH2CH2NH-cbz   11c) <CHEM> R = -NH(cbz) ; R2 = -CH2-S-Me m
Patent AT-E188280-T1 (AT)
Inventor: TURCI SERGE
IPC: B05D7/14
Filed: 1995-06-16
Granted: 2000-01-15
Abstract: Process for fabricating a composite elastomer-metal gasket for high pressure applications comprises: (a) coating an electro-galvanised steel sheet on both faces with a thin polymer-based film; (b) cutting and shaping the coated galvanised steel sheet into the required form to act as the reinforcing core layer of the gasket; (c) coating both faces of the reinforcing layer with a layer of elastomer, esp. by coating with a liq. elastomer compsn. that is not fully polymerised; and (d) curing the elastomer by thermal treatment. Pref. the step of coating with a thin film of polymer is carried out in-line directly after electroplating of the steel plate. The coating is pref. formed by applying and drying a liq. coating compsn. contg. the polymer in suspension and at least 0.1 wt.% phosphoric acid. The coating liq. may also contain at least 0.5 wt.% chromic acid (expressed as CrO3). The polymer is pref. an acrylic-based polymer. The coating film is pref. applied at a rate of 0.4-0.6 (0.5) g/m<2> and contains more than 1% phosphate cpds. (expressed as PO4) and opt. more than 1% cpds. based on Cr in the +VI oxidn. state (expressed as Cr). <IMAGE>
Patent AT-E209819-T1 (AT)
Inventor: LIN TIEN-LER
IPC: G11C16/02
Filed: 1995-01-05
Granted: 2001-12-15
Abstract: Flash EEPROM cell and array designs, and methods for programming the same result in efficient and accurate programming of a flash EEPROM chip. The flash EEPROM chip comprises a memory array (170) including at least M rows and N columns of flash EEPROM cells. M word lines (172) are each coupled to the flash EEPROM cells in one of the M rows of flash EEPROM cells. A plurality of bit lines (174) are each coupled to the flash EEPROM cells in one of the N columns of flash EEPROM cells. A page buffer (190) coupled to the plurality of bit lines supplies input data to N columns of flash EEPROM cells. Write control circuitry supplies programming voltages for programming input data to the flash EEPROM cells in response to the input data stored in the data input buffer (191). Verify circuity automatically verifies programming of the page by resetting bits in the page buffer for each cell which passes.
Patent AT-E216245-T1 (AT)
Inventor: MALLEY SERGE D
IPC: A61K45/06
Filed: 1994-12-20
Granted: 2002-05-15
Abstract: A method and composition for inhibiting the spread of a retrovirus such as HIV in a human cell population in which a retrovirus such as HIV is present has been found. The spread of the retrovirus is inhibited by treatment of the cells with a synergistic combination mixture of a dideoxy-ribonucleoside excluding AZT and hydroxycarbamide.
Patent AT-E231047-T1 (AT)
Inventor: FISHER KAWIKA S
IPC: B24D3/00
Filed: 1995-02-28
Granted: 2003-02-15
Abstract: The present invention is related to an abrasive tool comprising a core and abrasive segments attached to said core wherein said abrasive segments comprise a bond material and superabrasive grains and wherein said segments comprise at least two circumferentially spaced regions and wherein said superabrasive grains are alternately dispersed in said regions in high and low concentrations of superabrasive grains. The present invention is further related to an abrasive tool comprising a core and abrasive segments attached to said core wherein said abrasive segments comprise a bond material and superabrasive grains, wherein said abrasive segments comprise at least two circumferentially spaced regions and wherein said superabrasive grains are alternately dispersed in every other region.
Patent AT-E143423-T1 (AT)
Inventor: RUEF HARTMUT
IPC: D01D5/06
Filed: 1995-06-26
Granted: 1996-10-15
Abstract: The invention is concerned with a process for the production of cellulose fibres, wherein a solution of cellulose in an aqueous tertiary amine-oxide is extruded into filaments through spinning holes of a spinneret and the extruded filaments are conducted across an air gap into a substantially aqueous precipitation bath, characterized in that the extruded filaments, while being conducted across the air gap, are contacted with an aliphatic alcohol which is present exclusively in gaseous state. The process according to the invention produces cellulose fibres having a very reduced tendency to fibrillation.
Patent AT-E238437-T1 (AT)
Inventor: DECEMBER TIMOTHY S
IPC: C25D13/06
Filed: 1995-06-22
Granted: 2003-05-15
Abstract: An electrodeposition method is described where a conductive substrate is immersed in an electrodeposition coating composition comprising, in an aqueous medium: A) a resin having a plurality of acid-salted primary amine groups, and B) a curing agent having a plurality of cyclic carbonate groups.
Patent AT-E205845-T1 (AT)
Inventor: DVORAK CHARLES ALOIS
IPC: A61K31/435
Filed: 1995-07-01
Granted: 2001-10-15
Abstract: This invention relates to processes for preparing 2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one, particularly 2-(1-azabicyclo[2.2.2]oct-3S-yl)-2, 3,3aS,4,5,6-tetrahydro-1H-benz[de]isoquinolin-1-one, and to intermediates useful in such processes.
Patent AT-E198915-T1 (AT)
Inventor: GUPTA ALOK KUMAR
IPC: C22F1/00
Filed: 1995-09-05
Granted: 2001-02-15
Abstract: A process of producing solution heat treated aluminum alloy sheet material comprises subjecting hot- or cold-rolled aluminum alloy sheet to solution heat treatment followed by quenching and, before substantial age hardening has taken place, subjecting the alloy sheet material to one or more subsequent heat treatments involving heating the material to a peak temperature in the range of 100 DEG  to 300 DEG  C. (preferably 130 DEG -270 DEG  C.), holding the material at the peak temperature for a period of time less than about 1 minute, and cooling the alloy from the peak temperature to a temperature of 85 DEG  C. or less. The sheet material treated in this way can be used for automotive panels and has good a good "paint bake response", i.e. an increase in yield strength from the T4 temper to the T8X temper upon painting and baking of the panels.
Patent AT-E350390-T1 (AT)
Inventor: COOPER JUAN ANTON
IPC: A61K39/00
Filed: 1995-10-16
Granted: 2007-01-15
Abstract: The present invention relates generally to chimeric peptides comprising one or more protective epitopes in a conformation enabling inmunological interactivity and to vaccine compositions comprising same. The present invention is particularly directed to a chimeric peptide capable of inducing protecting antibodies against Group A streptococci.
Patent AT-E194567-T1 (AT)
Inventor: RELLO ROBERT M
IPC: B65C3/12
Filed: 1995-11-20
Granted: 2000-07-15
Abstract: A method and apparatus is disclosed for applying a label onto a substantially cylindrical article. The label drum (32) defines an article wrapping position. A thin layer, heat activated adhesive backed label (5) is fed onto a label receiving position of the drum. The label receiving positions of the drum are formed of a substantially smooth, resilient material, such as silicon. The label drum is rotated to move the label retained thereon into the article wrapping position. As the label is moved, the adhesive is heated so that the adhesive obtains a sufficient temperature to melt. A jet of air is blown onto the resilient surface for cooling the surface during subsequent label applying and ensuring rapid cooling of melted adhesive during labeling.
Patent AT-E167493-T1 (AT)
Inventor: AUSTIN ANNE-MARIE B
IPC: C07C309/41
Filed: 1996-02-14
Granted: 1998-07-15
Abstract: Water soluble polymers are prepared from an allyloxybenzenesulfonic acid monomer, a methallyl sulfonic acid monomer, a copolymerizable nonionic monomer, and a copolymerizable olefinically unsaturated carboxylic acid monomer. The polymers are used to disperse particulate matter and to inhibit the formation and deposition of mineral scale in aqueous systems and are used in detergent compositions.
Patent AT-E211302-T1 (AT)
Inventor: BLECKER ARMIN
IPC: H01J9/385
Filed: 1996-03-07
Granted: 2002-01-15
Abstract: The connection appts. connects a suction joint (1) of a vacuum pumping installation to the neck (10) of the tube in a jig with lateral guidance rollers (4) running on rails (6) whose profile causes levers (5) to be pivoted slightly outwards against compression springs (9). This movement varies the spacing between centring rollers (8) which guide the evacuation stem (11) of the tube safely into the sealing ring (13) of the suction joint. At the same time spring contacts (15) in a holder (16) are brought up to connections (12) with the tube cathode until contact is made with the roller (18) of a release unit (17).
Patent AT-E164401-T1 (AT)
Inventor: BLEAKLEY IAN STUART
IPC: C01F11/18
Filed: 1996-04-12
Granted: 1998-04-15
Abstract: A method of treating reject from a plant for de-inking waste paper which reject comprises a mixture of ink particles, inorganic particles and fibres includes the step of forming in an aqueous suspension or slurry comprising said reject a precipitate of a substantially white insoluble salt which entrains or aggregates ink particles, inorganic particles and fibres contained in said reject whereby the darkness of the reject is reduced by formation of the precipitate. The precipitate may comprise calcium carbonate formed by reacting carbon dioxide with calcium hydroxide in the said suspension. The precipitate and entrained or aggregate material therein may be separated for re-use as a particulate coating or filler material. The said product may be separated from water which after separation is clearer than when originally treated and is recycled for re-use. The said reject may be a slurry or sludge produced from a flotation process of a waste paper de-inking plant.
Patent AT-E208396-T1 (AT)
Inventor: ASZODI JOZSEF
IPC: C07D519/06
Filed: 1996-08-13
Granted: 2001-11-15
Abstract: Syn isomer of cpds. of formula (I), and their salts, are new. In (I), R1-R3, R5 = H, halo, OH, 1-4C alkyl (opt. substd. by halo, 1-4C alkyloxy, SH etc.); R4 = OH or 1-8C acyloxy; R7 = H or (1-3C alkyloxy)carbonyl; A = e.g. H, an equivalent of alkali(ne earth) metal, Mg, ammonium or aminated organic base etc.; or CO2A = CO2-; wavy line shows that CH2R6 can be in E- or Z-position; R6 = e.g. quat. ammonium or gp. of formula (i); X = CH2, NH, O or S; and Y, T, U, V, W and Z = CH or N; with the provisos.
Patent AT-E209456-T1 (AT)
Inventor: ZIGERLIG MAX
IPC: A46D3/04
Filed: 1996-09-06
Granted: 2001-12-15
Abstract: A process for making rotating brush (21), in particular, the type used in automatic car washing facilities, and comprising a support (21s) which has inner face (6) and outer face (7), having attached to the outer face flexible cleaning elements (3n), wherein the process includes the following stages:   a) preparation of mold (24) capable of making desired rotating brush (21); b) arrangement of said flexible cleaning elements (3n) with one end inserted into mold (24) and the other end projecting outwardly; c) injection into the mold (24) of components in the fluid state intermixed to form synthetic resin (8) which is able to polymerize; d) opening of mold (24) once polymerization is complete and extraction of brush (21) in which these flexible cleaning elements (3n) are attached to this support (21s) because they are embedded in the polymerized resin.   <IMAGE>
Patent AT-E245338-T1 (AT)
Inventor: TARGETTI PAOLO
IPC: F21S2/00
Filed: 1996-12-04
Granted: 2003-08-15
Abstract: A modular support structure for lighting apparatuses, as well as other electrical and electronic devices and their relative instrumentation, comprising a plurality of modular elements (1) having a box-like form with an open main face (2), through which said devices are visible, as well as a series of consecutive faces (6,7,8) which are angled in succession and form connection surfaces for adjacent modular elements. Modular element (1) preferably comprises a first pair of faces (6) orthogonal to the main face, a second pair of faces (7) consecutive with the first pair of faces and angled with respect to them and a third face (8) which unites the two faces of the second pair and is substantially parallel to the main face. Preferably, the faces of the first and second pairs (6,7) form an angle of about 150 DEG  whereas the faces of the second pair (7) are angled by about 120 DEG  with the third face (8). The resulting structure is adaptable to a large number of applications, is self-supporting and makes it possible to realize structures of various forms and arrangements for the support of apparatuses. <IMAGE>
Patent AT-E170124-T1 (AT)
Inventor: BISIO GIOVANNI
IPC: B28B7/36
Filed: 1996-12-13
Granted: 1998-09-15
Abstract: A plate (1) for press-moulding dies of refractory bricks and the like, comprising a bearing metal slab (2) to one face of which a lining (4) of high wear-resistant material, normally hard metal, is applied, which is formed by a number of adjacent tiles (7, 8, 9) arranged in an orderly way along parallel lines (6). The adjoining sides between adjacent tiles (7, 8, 9) are at least in part curved. <IMAGE>
Patent AT-E177467-T1 (AT)
Inventor: CAPROTTI RINALDO
IPC: C10L1/22
Filed: 1996-01-09
Granted: 1999-03-15
Abstract: A fuel oil composition comprising a major proportion of a liquid hydrocarbon middle distillate fuel oil having a sulphur content of not greater than 0.2 % by weight of the fuel oil and a minor proportion of a hydroxy amine which improves the lubricity of the fuel oil. The inclusion of the hydroxy amine in the fuel also markedly reduces the foaming tendency of the fuel oil.
Patent AT-E191093-T1 (AT)
Inventor: ZHU JIE
IPC: H04N1/387
Filed: 1996-07-24
Granted: 2000-04-15
Abstract: A method and system including a high speed computer algorithm for rotating images stored in a computer memory, such as those captured by a CCD array. The method and system may be used with an over-the-belt optical character recognition (OCR) reader that captures a pixelized image of the surface of a parcel as it moves along a conveyor. A run-length encoded output image is obtained from a run-length encoded input image, wherein the output image is a rotated version of the input image. A predefined pixel mapping sequence for a rotation angle with a rational tangent is used to map image pixel data. Mapping image pixel data using a predefined pixel mapping sequence allows rotation without floating point computations, and allows the use of a reverse pixel mapping technique to map output runs from an input image in order to avoid the creation of holes or artifacts in the output image. Mapped output runs are scaled to preserve the aspect ratio of the rotated image. The order of processing the elements of the input run-length input table is selected so as to directly create a run-length encoded output table.
Patent AT-E219195-T1 (AT)
Inventor: VON ROENN THOMAS
IPC: E03D11/12
Filed: 1996-02-23
Granted: 2002-06-15
Abstract: The body (1) of a urinal that may be equipped with a flushing device is designed as a tubular structure that has a novel geometry and may be secured to a wall or stand. The front side of the urinal body (1) has a longitudinal slot (8) for receiving urine. The longitudinal slot (8) extends vertically or in a plane that is or may be inclined. The narrow design of the urinal, as well as the vertically elongated, narrow urine-receiving opening allow an advantageous urinal to be obtained for standing users of various heights.
Patent AT-E269005-T1 (AT)
Inventor: TRIMBO SUSAN L
IPC: A23L1/30
Filed: 1996-10-15
Granted: 2004-07-15
Abstract: The present invention provides a method and nutritional composition for providing nutrition to pediatric patients. The methods of the present invention are especially directed to pediatric patients recovering from moderate trauma, burns or surgery. Pursuant to the present invention, the enteral composition includes a rapidly emptying, low gastric reflux protein source comprising approximately 10% to 14% of the total calories, a carbohydrate source and a lipid source comprising a mixture of medium and long chain triglycerides, wherein at least 20% of the lipid source are medium chain triglycerides.
Patent AT-E221880-T1 (AT)
Inventor: VIGH LASZLO
IPC: A61K31/15
Filed: 1996-11-01
Granted: 2002-08-15
Abstract: A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II). The invention also provides novel hydroxylamine derivatives falling within the scope of the formulae (I) and (II) as well as pharmaceutical and/or cosmetical compositions comprising the said compounds.
Patent AT-E266415-T1 (AT)
Inventor: REINKE PETRA
IPC: A61M1/36
Filed: 1996-11-15
Granted: 2004-05-15
Abstract: Immunoapheresis treatment for cardiomyopathy comprises passing the patient's plasma over a column having coupled thereto a specific ligand for human immunoglobulin, thereby removing a significant portion of the immunoglobulin from the patient's plasma, and then reinfusing the plasma to the patient. The invention is the use of a specific ligand for human immunoglobulin in the manufacture of a column having the ligand coupled thereto, the column being useful for immunoapheresis treatment of a patient with cardiomyopathy. The specific ligand binds, and thereby removes, human autoantibodies which are harmful to cardiac tissue such as antibodies against beta<SUB>1</SUB>-adrenergic receptors, ADP-ATP carriers, alpha and beta myosin heavy chains, and adenine nucleotide translocators. Immunoapheresis treatment using the column results in improvement of hemodynamic parameters such as mean arterial pressure, mean pulmonary pressure, pumonary capillary wedge pressure, right atrial pressure, cardiac output, cariac index, stroke volume index, and systemic vascular resistance.