baber/WOPTO huggingface dataset:
Patent NZ-504098-A (NZ)
Title: Pharmaceutical compositions containing cyclodextrins and taxoids
Inventor: GECZY JOSEPH M
IPC: A61K47/48
Filed: 1998-11-09
Abstract: An instantly soluble solid product for use as a pharmaceutical and its solutions in aqueous solvents are prepared by dissolving in ethanol a taxoid preferably paclitaxel or docetaxel and then either: i) Adding a solid cyclodextrin derivative either acetyl-g- cyclodextrin or hydroxy-propyl-b-cyclodextrin (and optionally other water-soluble auxiliary materials usual in pharmaceuticals for parenteral purposes) and dissolving the mixture in an aqueous solvent and lyophilising to obtain a solid; or ii) Adding a lyophilised solid cyclodextrin derivative either acetyl-g- cyclodextrin or hydroxy-propyl-b-cyclodextrin (and optionally other water-soluble auxiliary materials usual in pharmaceuticals for parenteral purposes) and then evaporating the solvent and drying to obtain a solid; or iii) Admixing the solution with solid large surface area preferably lyophilised cyclodextrin derivative either acetyl-g- cyclodextrin or hydroxy-propyl-b-cyclodextrin, and optionally other water-soluble auxiliary materials usual in pharmaceuticals for parenteral purposes and then dissolving with an aqueous solvent optionally in the presence of an isotonizing additive to obtain a solution; The solid and solutions contain the taxoid as an active ingredient, a cyclodextrin and optionally other water-soluble auxiliary materials usual in pharmaceuticals for parenteral purposes whereby the weight ratio of the taxoid : cyclodextrin ranges between 1 : 25 and 1 : 400 with the proviso that when hydroxy-propyl-b-cyclodextrin is used the taxoid can only be docetaxel in a 1 25 to 1 : 100 taxoid : cyclodextrin weight ratio. When steps i) or ii) are used the solid can be dissolved in an aqueous solvent to obtain a parenteral solution ready for direct medical treatment. The pharmaceutical prepared can be used for treating unwanted cell proliferation
Patent NZ-507703-A (NZ)
Title: A metered filling apparatus, in use having a container- engaging body being movable relative to the main body to cause valve stem to be selectively positioned in an extended closed position
Inventor: BRENNAN JOHN
IPC: B65B31/04
Filed: 1999-04-21
Abstract: A filling apparatus for introducing into a container a suspension or solution of a substance, in particular a pharmaceutical substance, in a propellant under pressure, comprises: a main body including a passageway for communicating, in use, with a valve stem extending from a head of a body of a container. The container comprises a metering chamber selectively communicatable by the valve stem with the atmosphere and a storage chamber defined by the body; a fill actuator comprising a filling valve assembly in communication with the passageway for selectively introducing thereinto propellant under pressure containing a substance in a suspension or solution; an exhaust actuator comprising an exhaust valve assembly in communication with the passageway for selectively exhausting therefrom propellant under pressure containing substance; and a container-engaging body in communication with the passageway for receiving, in use, the head of the body of the container, the container-engaging body being movable relative to the main body so as thereby to cause the valve stem of the container to be selectively positioned in an extended closed position, a depressed open position or an intermediate position therebetween, in which intermediate position the metering chamber of the container is closed to the atmosphere. Also described is a method of introducing into a container a suspension or solution of a substance in a propellant under pressure
Patent NZ-509068-A (NZ)
Title: Process for the production of an aqueous monoester peroxycarboxylic acid solution, the solution obtainable by this process, and its use as disinfectant
Inventor: CARR GRAHAM
IPC: C07C407/00
Filed: 1999-06-01
Abstract: A process for the production of an aqueous monoester peroxycarboxylic acid solution by reaction of a peroxygen compound with at least one polycarboxylic acid with at least one alcohol.  The polycarboxylic acid can be dicarboxylic acid containing up to 20 carbon atoms and in an amount from 0.02 to 65 % weight if the reaction mixture.  The peroxygen can be selected from hydrogen peroxide, inorganic peracids, organic peracids, persalts, the peroxygen compound being used in an amount of 0.05 to 30% weight of the reaction mixture.
Patent NZ-512384-A (NZ)
Title: Removeable end cover for cylinder shaped food rolls
Inventor: MASON MARVIN GENE
IPC: A23L3/00
Filed: 1999-12-16
Abstract: An end cover for detachable connection on the end of a cylindrical shaped food roll (10). The end cover has an end plate (32) with an external side (38) that displays information such as advertising or marketing indicia. A retaining member (34) extends from the end plate (32) and forms an interference fit with the external surface of the food roll when the end cover is installed onto the food roll.
Patent NZ-512732-A (NZ)
Title: Piperidine, tetrahydropyridine and piperazine derivatives useful in treating affective disorders
Inventor: MOLTZEN EJNER KNUD
IPC: C07D307/81
Filed: 2000-01-21
Abstract: A piperidine, tetrahydropyridine or piperazine derivative or an enantiomer or any mixture thereof, or an acid addition salt thereof has the formula (I) wherein: B is alkylene, alkenylene or alkynylene; X is -O-, -S-, or -CR4R5-; and Y is -CR6R7-, -CR6R7-CR8R9-, or -CR6=CR7- or X and Y together form a group -CR4=CR5-, or -CR4=CR5-CR6R7-; Z is -O-, or -S-; W is N, C, or CH, and the dotted line is an optional bond; R4 to R9 are independently hydrogen, halogen, trifluoromethyl, optionally substituted alkyl, alkenyl, alkynyl, C3-7-cycloalkyl, cycloalkyl-alkyl, alkoxy, alkylthio, amino, alkylamino, dialkylamino, or optionally substituted phenylamino or phenyl-alkylamino, acylamino, hydroxy, -SH, cyano, nitro, -COOR18 or -SO2-R19; R18 and R19 are as defined in the specification and A is a bicyclic ring of formulae (1f) to (1r) which is attached to the reminder of the compound of formula (I) via a carbon atom or nitrogen atom in any of the two rings in structures (1g), (1h), (1j), (1k), (1m), (1n), (1o) and (1p) and via the benzene ring only in structures (1f), (1i), (1q) and (1r) and may be substituted and E6 is O or S. The compounds are useful in treating depression or psychosis or panic, obsessive compulsive or eating or anxiety disorders.
Patent NZ-512985-A (NZ)
Title: Flat panel sound radiator with special edge details
Inventor: ROY KENNETH P
IPC: H04R1/02
Filed: 2001-07-17
Abstract: A flat panel radiator apparatus that produces a broad acoustic radiation pattern suitable for sound masking, for use in a ceiling grid that includes a plurality of main beams and crossbeams with the crossbeams supported by the main beams to define an opening for mounting a flat panel radiator, the apparatus comprising: (a) A frame (230) for supporting the flat panel radiator in the ceiling grid, the frame including an upper plate, a first side plate and a lower plate, wherein the first side plate is rigidly fixed between a first edge of the lower plate and the upper plate, wherein the upper plate is rigidly fixed to the upper portion of the first side plate to form a cross-section having a Z-shaped portion. (b) An isolation element (222) affixed to the frame to isolate the flat panel radiator (200) from the beams of the ceiling grid. (c) A substantially acoustically transparent facing (216) disposed below the frame and capable of extending across the opening defined by the plurality of main beams and crossbeams.
Patent NZ-514197-A (NZ)
Title: Method of eliminating, reducing or preventing parasites in fish using emamectin
Inventor: HUQ ABU S
IPC: A23K20/195
Filed: 2000-04-06
Abstract: A method of eliminating, reducing or preventing parasites in a fish population is disclosed, wherein the method comprises feeding emamectin or a salt thereof to the fish population at a daily dose of 25 mg to 400 mg per kg of fish biomass per day for a period of 3-14 days. Also disclosed is a kit for preparing a medicated fish feed for eliminating, reducing or preventing parasites in a fish population, the kit having a supply of emamectin or a salt thereof and printed instructions for feeding the emamectin or emamectin salt at a daily dose of 25 mg to 400 mg per kg of fish biomass per day for a period of 3-14 days.
Patent NZ-516570-A (NZ)
Title: Cap with stretchable band
Inventor: HIGGS MICHAEL
IPC: A42B1/06
Filed: 2000-07-14
Abstract: A peak cap (1) having a crown (2) with an inner elastically stretchable band (13) positioned to extend at least partway along a lower encircling edge (10) and a liner of stretchable fabric (12) secured to be on an inner side of the elastic material of the band (13). Also described is a band with the liner in the form of a sleeve through which an elastic member extends and where the liner but not the elastic material is secured to the lower edge of the crown (2).
Patent NZ-517034-A (NZ)
Title: Methods and apparatus for purifying air using mixed liquid
Inventor: SON CHEOLSOO
IPC: B01D53/14
Filed: 2000-07-05
Abstract: Methods and apparatus for purifying contaminated air using mixed liquid are disclosed. The invention includes an air inlet structure for taking in contaminated air, an air purifying compartment connected to the air inlet structure at one end for purifying contaminated air, and an air outlet structure connected to the air purifying compartment at another end for discharging purified air to the outside. The invention uses mixed liquid in its air purifying method. The invention includes a method that uses centrifugal force to form a mixed liquid filter, a method that takes in contaminated air, a method that purifies the contaminated air, and a method that discharges purified air to the outside. The invention can achieve a high degree of economic efficiency and a high degree of purification efficiency.
Patent NZ-517951-A (NZ)
Title: Fibrinolytically active polypeptide
Inventor: BOONE THOMAS CHARLES
IPC: C12N15/57
Filed: 2000-09-29
Abstract: A fibrinolytically active metalloproteinase polypeptide (called "novel acting thrombolytic") which is useful for blood clot lysis in vivo and methods and materials for its production by recombinant expression are described.
Patent NZ-520927-A (NZ)
Title: Orally administered controlled delivery system for once daily administration of ciprofloxacin
Inventor: TALWAR NARESH
IPC: A61P31/04
Filed: 2001-02-28
Abstract: A sustained release solid dosage form of ciprofloxacin that when orally administered under fed conditions, provides properties of mean peak serum/plasma concentration, area under the serum/plasma concentration-time curve above the minimum inhibitory concentrations, durations above minimum inhibitory serum/plasma concentrations, of at least 70% that of divided does immediate release ciprofloxacin.
Patent NZ-522696-A (NZ)
Title: Substituted quinazoline derivatives and their use as inhibitors
Inventor: MORTLOCK ANDREW
IPC: C07D409/14
Filed: 2001-06-21
Abstract: Described are compounds of formula (IA), wherein: X is O, S, S(O) or S(O)2, or NR6 where R6 is H or alkyl, R5a is a 5-membered heteroaromatic ring selected from a group of formula (a), (b), (c), (d), (e), (f), (g), (h), (i) or (j), and the remaining substituents are defined herein. The compounds are used in the manufacture of medicaments for the treatment of diseases mediated by the inhibition of aurora 2 kinase, such as cancer.
Patent NZ-523359-A (NZ)
Title: Growth hormone secretagogues; useful for treating systemic lupus erythematosus and inflammatory bowel disease
Inventor: BUSCH FRANK ROBERT
IPC: A61K31/55
Filed: 2001-06-18
Abstract: Use of growth hormone secretagogues (GHS) that are suitable for treating systemic lupus erythematosus and inflammatory bowel disease are disclosed, wherein the growth hormone secretagogues (GHS) is a compound of formula (I), where the variables are as defined in the specification.
Patent NZ-524133-A (NZ)
Title: Producing paper fabric/clothing using spiral windings where two laminated layers are offset
Inventor: HANSEN ROBERT A
IPC: D21F1/10
Filed: 2001-10-03
Abstract: A papermaker's fabric is manufactured by spirally winding a laminated structure (16) in a plurality of turns. The laminated structure has a bottom layer (36) and a top layer (34), both of which are strips having a common width. The bottom layer (36) and the top layer (34) are laminated to one another in a transversely offset manner, so that an unlaminated portion of the bottom layer (36) is along one lateral edge of the laminated structure and an unlaminated portion of the top layer (34) is along the other lateral edge. When the laminated structure is spirally wound, the unlaminated portion of the top layer in one turn overlies the unlaminated portion of the bottom layer in an adjacent turn. These are joined to one another to form the papermaker's fabric from the spirally wound structure.
Patent NZ-524642-A (NZ)
Title: Methods for stable transduction of cells with viral vectors
Inventor: HUMEAU LAURENT
IPC: C12N15/09
Filed: 2001-08-29
Abstract: A method for stable transduction of primary cells of the hematopoietic system or hematopoietic stem cells comprising contacting the primary cell or hematopoietic stem cell at the same time in vitro or ex vivo with a lentiviral vector and at least one cell surface binding molecule and a) at least about 75% of the cells are stably transduced after about 7-10 days, or at least about 14 days, and optionally at least 75% of cells remain stably transduced after about 14 days, or b) the cells are transduced with the vector of a multiplicity of infection (MOI) such that copies of the vector per transduced cell is from about 1 to about 100: wherein the cell surface molecule does not induce apoptosis and the cell surface binding molecule results in the cell being more receptive to transduction by a viral vector, and optionally the cell surface binding molecule comprises a polypeptide, a lipid, a nucleic acid, a carbohydrate or an ion.
Patent NZ-525246-A (NZ)
Title: New derivatives of cyano-aryl (or cyanoheteroaryl)-carbonyl-piperazinyl-pyrimidines, their preparation and application as medication
Inventor: CORBERA-ARJONA JORDI
IPC: C07D213/00
Filed: 2001-10-10
Abstract: New derivatives of cyano-aryl (or cyanoheteroaryl)-carbonyl-piperazinyl-pyrimidines, formula I (see below) are disclosed. R1 represents an OR3 radical, wherein R3 represents a radical deriving from a saturated hydrocarbon with a linear or branched chain of 1 to 4 carbon atoms and R2 represents a phenyl radical substituted at least by a cyano radical (-CN), or a radical of a 5 or 6-membered heteroaromatic ring substituted by at least one cyano radical (-CN). The physiologically acceptable salts of said derivatives can be used in human and/or veterinary therapeutic applications as sedatives, anticonvulsants, hypnotics and general anaesthetics.
Patent NZ-525752-A (NZ)
Title: HIV peptides, antigens, vaccine compositions, immunoassay kit and a method of detecting antibodies induced by HIV
Inventor: SOERENSEN BIRGER
IPC: G01N33/569
Filed: 2000-03-02
Abstract: Peptides and modified peptides based on conserved regions of a human immunodeficiency virus (HIV) protein capable of inducing an HIV-1 specific immune response without antagonizing the cytotoxic T-cell activity in order to achieve an effective prophylactic and therapeutic vaccine against HIV. Such peptides are useful as vaccines and for detecting antibodies induced by the HIV in a sample. The peptides are based on conserved regions of HIV gag p24 proteins. Antigens in free- or carrier-bound form comprising at least one of the said peptides, vaccine compositions containing at least one of the antigens, immunoassay kits and a method of detecting antibodies induced by HIV or HIV specific peptides using such antigens, are described. (62) Divided out of 514619
Patent NZ-528482-A (NZ)
Title: Fragrance-containing gel for delivering fragrance from structured liquid detergent compositions
Inventor: PASHKOVSKI EVGUENI E
IPC: C11D17/00
Filed: 2002-03-25
Abstract: A stable fragrance-containing gel is provided which is capable of being mixed with a fragrance-free base composition comprised of a homogeneous aqueous structured liquid detergent composition to form a pourable fragrance-containing homogeneous aqueous structured detergent composition. The resulting structured detergent composition provides enhanced deposition and longevity of fragrance upon fabrics laundered with such fragrance-containing detergent composition as compared to laundering with an otherwise identical composition containing the same level of fragrance but in the absence of said fragrance-containing gel, said fragrance-containing gel comprising: (a) a polyacrylic acid polymer having an average particle size below about 1 mm; (b) water in an amount sufficient to form a gel with said polymer; (c) a fragrance dispersed within said gel; and (d) a non-ionic surfactant in an amount sufficient to emulsify said fragrance and enhance its dispersion within said gel to provide a stable fragrance-containing gel.
Patent NZ-530931-A (NZ)
Title: Alkyne-aryl substituted 1,8-naphthyridin- 4(1H)-ones in the treatment of pulmonary disorders
Inventor: GUAY DANIEL
IPC: C07D471/04
Filed: 2002-08-27
Abstract: Compounds represented by Formula (I) or a pharmaceutically acceptable salt thereof, are phosphodiesterase 4 inhibitors useful in the treatment of asthma and inflammation. R is H,-C1-6alkyl or-C3-6cycloalkyl; R1 is H, or a-C1-6alkyl, -C3-6cycloalkyl, -C1-6alkoxy, C2-6alkenyl, -C3-6alkynyl, -C(O)-C1-6alkyl, -C(O)-aryl, -(C0-6alkyl)-SOn-(C1- 6alkyl),-6alkyl)-SOn-(aryl), phenyl, heteroaryl, orheterocycloC37alkyl group, wherein any of the groups is optionally substituted with 1-3 independent-C1-6alkyl, C1-6alkoxy, OH, -N (C0-6alkyl)(C0-6alkyl), -(C0-6alkyl)-SOn-(C1-6alkyl) nitro, CN,=N-O-C1-6alkyl,-O-N=C1-6alkyl, or halogen substituents; R2 is absent, H, halogen,-C1-6alkyl,-C3-6cycloalkyl, -C1-6alkyl(C3-6cycloalkyl)(C3-6cycloalkyl), -C1-6alkoxy, phenyl, heteroaryl, heterocycloC3-7alkyl, nitro, CN, =N-O-C1-6alkyl, -O-N=C1-6alkyl, -N(C0- 6alkyl) (C0-6alkyl), -NHSOn-(C1-6alkyl), -NHC(O)-C1-6alkyl, -NHC(O)-aryl, -C(O)-C1-6alkyl, -C(O)-O-C1-6alkyl, -C1-6alkyl (=N-OH), -C (N=NOH) C1-6alkyl, -C0-6alkyl (oxy)Cl-6alkyl-phenyl,-SOnNH (C)0-6alkyl), or- (C0-6alkyl)-SOn- (C1- 6alkyl), wherein the phenyl, heteroaryl or heterocycloC3-7alkyl is optionally substituted with halogen,-Cl-6alkyl,-C1-6alkoxy, hydroxy, -N (C0 6alkyl) (C0 6alkyl), or-C(O)-O-Cl-6alkyl, and any alkyl is optionally substituted with 1-6 independent halogen or-OH substituents; n is 0, 1, or 2 ; R3 is absent, H, OH,-N (C0-6alkyl(C0-6alkyl), halogen or C1-6alkyl, wherein any alkyl is optionally substituted with 1-6 independent halogen, OH, or-N (Co 6alkyl) (Co 6alkyl) substituents; R4, R5, R6, and R7 each independently is H, halogen,-C1-6alkyl,-C1-6alkoxy,-SOn-(C1 6alkyl), nitro, CN, or-N(C0 6alkyl) (C0 6alkyl), and any alkyl is optionally substituted with 1-6 independent halogen or-OH substituents; and R8 is phenyl, pyridyl, pyrimidyl, indolyl, quinolinyl, thienyl, pyridonyl, oxazolyl, oxadiazolyl, thiazolyl, thiadiazolyl, or imidazolyl; or oxides thereof when R8 is a heteroaryl; orH,-Cl-6alkyl, or-C3-6cycloalkyl, and any alkyl is optionally substituted with 1-6 independent halogen,-N (C0-6alkyl)(C0-6alkyl), -N(C3- 7cycloalkyl)(C0-6alkyl),-N (C3-7cycloalkyl) (C3-7cycloalkyl), N-heterocycloC4-7alkyl,-SOn-6alkyl),-SOn-(aryl), or -OH substituents.
Patent NZ-530980-A (NZ)
Title: Method and apparatus for producing a continuous food shaped as a bar and a belt conveyor used for its production
Inventor: OKAIZUMI HIROYUKI
IPC: A23P1/08
Filed: 2003-02-26
Abstract: A method for producing a food shaped as a continuous bar by placing a continuous inner material on a continuous strip of an outer layer material that is transferred on a former belt, comprising the steps of placing food material that includes the inner material placed on the strip of the outer layer material in a channel space defined by the former belt while it is running; and shaping part of the former belt that is located at the channel space as a sleeve by pushing and joining edges of the former belt by a pushing device to allow edges of the outer layer material to be joined.
Patent NZ-531121-A (NZ)
Title: Push-in pipe connector with pretension spring between collar-and-fingers component and connector
Inventor: WHITE MICHAEL
IPC: F16L37/091
Filed: 2004-02-12
Abstract: A pretension spring is located between the ring 4 of a collar-and-fingers component and the adjacent end of the connector body 1. A number of advantages are noted including assisting in gripping of an inserted pipe end p.
Patent NZ-534892-A (NZ)
Title: Outboard motor mounting clamp
Inventor: AROA MARC THOMAS
IPC: B63H20/06
Filed: 2003-01-29
Abstract: A clamp allows quick attachment of an outboard motor (no shown but secured to existing mounting bracket (20)), to boat transom (25). Plate (27) is bolted (30) to bracket (20). Next, a user slides yoke (22) with respect to plate (27) until noses (24) of arms (23) contact transom (25). Turning handle (45) by 90 DEG then secures shaft (37), which passes through yoke (22), to plate (27) as threaded segments on shaft (37) engage with threaded segments inside a bore in plate (27), Pivoting handle (45) down will then press cam faces (42) of cam (41) against yoke (22), clamping arms (23) to transom (25). In contrast, in another embodiment, simply pivoting a bifurcated handle of a clamp both takes up slack and directly engages transom (25).
Patent NZ-535383-A (NZ)
Title: Anti-inflammatory compounds
Inventor: PEARCE ALLISON NORRIE
Filed: 2004-09-17
Abstract: Disclosed are isolated or substantially pure compounds of formula (I) or formula (II) which have anti-inflammatory activity and comprise a new class of NSAIDs. The compounds are therefore useful in pharmaceutical compositions for treating inflammatory diseases or disorders.
Patent NZ-535455-A (NZ)
Title: Controlled release dosage forms
Inventor: ZHOU FANG
IPC: A61K9/32
Filed: 2003-02-21
Abstract: Disclosed is a controlled release oral dosage form comprising: a) a core, wherein said core comprises: i) an effective amount of at least one therapeutically active agent, and ii) at least one first pharmaceutically acceptable excipient, and b) a stable controlled release monolithic coating surrounding the core, wherein the stable controlled release monolithic coating is formed by a process comprising coating the core with a coating composition to form a coated core, and curing the coated core to form the stable controlled release monolithic coating, wherein the coating composition comprises i) an aqueous dispersion of a neutral ester copolymer without any functional groups; ii) a poly glycol having a melting point of at least 55 degrees Celsius, and iii) at least one second pharmaceutically acceptable excipient; wherein the curing is conducted at a temperature at least equal to or greater than the melting point of the poly glycol.
Patent NZ-536360-A (NZ)
Title: Compositions for therapeutic use comprising a vitamin, a metal salt and insulin or a growth hormone
Inventor: AL-SARI MISHAL HAMID
IPC: A61K8/00
Filed: 2003-05-27
Abstract: Disclosed is an injectable medicament composition having a variety of therapeutic and cosmetic uses comprising: (i) vitamin C; (ii) a metal salt that provides metal ions in vivo; and (iii) camomile or an active component thereof. The composition may additionally contain insulin and may be used to treat for example, genetic disorders, skin diseases, cancer and viral infections.