baber/WOPTO huggingface dataset:
Patent CA-2623659-A1 (CA)
Title: Targeted delivery of compounds using multimerization technology
Inventor: ABULROB ABEDELANASSER
IPC: A61K31/00
Filed: 2006-09-15
Abstract: There is disclosed herein subunits and multimers of subunits suitable for use in inducing the transport of one or more cargo substances into a cell and in some instances across a cell. The subunits may have a targeting domain such as an antibody or antibody fragment, a multimerization domain, such as a verotoxin B-subunit mutant scaffold, and a cargo molecule such as a drug or imaging agent, which may be directly linked to the subunit or may be packaged in a liposome, nanoparticle, or the like. In some instances the targeting domain may have affinity for a blood-brain barrier antigen and may be capable of inducing cell mediated transcytosis to facilitate delivery of the cargo molecule across the blood-brain barrier. In some instances the targeting region may have affinity for a cancer antigen and may be capable of inducing cell-mediated endocytosis.
Patent CA-2623762-A1 (CA)
Inventor: BHANOT SANJAY
IPC: A61K31/712
Filed: 2006-09-19
Abstract: Compounds, compositions and methods are provided for modulating the expression of glucagon receptor. The compositions comprise antisense compounds, particularly antisense oligonucleotides which have particular in vivo properties, targeted to nucleic acids encoding glucagon receptor. Methods of using these compounds for modulation of glucagon receptor expression and for treatment of diseases are provided.
Patent CA-2624341-A1 (CA)
Inventor: VOELLMICKE JOHN
IPC: A61F2/44
Filed: 2006-09-14
Abstract: Intravertebral bone stents and tamps made from shape memory metal
Patent CA-2625577-A1 (CA)
Inventor: PARADOWSKI HENRI
IPC: F25J3/02
Filed: 2006-10-10
Abstract: Dans ce procédé, on refroidit le courant de GNL (11) avec un fluide réfrigérant (83) dans un premier échangeur thermique (19). Le fluide réfrigérant (83) subit un deuxième cycle de réfrigération (21) semi-ouvert, indépendant du premier cycle (15). Le procédé comprend une étape d'introduction du courant de GNL sous-refroidi (59) dans une colonne de distillation (49) et une étape de récupération d'un courant de gaz (69) en tête de la colonne (49). Le deuxième cycle de réfrigération (21) comporte une étape de formation d'un courant (73) de fluide réfrigérant à partir d'une partie du courant de gaz de tête (69), une étape de compression du courant de fluide réfrigérant (73) jusqu'à une pression haute, puis une étape de détente d'une partie (81) du courant de fluide réfrigérant comprimé (75) pour former un courant essentiellement liquide (83) de sous-refroidissement. Le courant essentiellement liquide (83) est vaporisé dans le premier échangeur thermique (19).
Patent CA-2629094-A1 (CA)
Inventor: BENEDETTI PAOLO
IPC: B65D51/22
Filed: 2006-11-30
Abstract: There is described a method of producing plastic tops (1) for sealed containers of pourable food products; the method starts with a plastic sheet material having a layer of gas-barrier material, and includes the steps of forming a contoured body (11) having an annular base portion (2, 12), and a neck portion (3, 13), which projects from the base portion (2, 12), defines, with the base portion, a pour opening (5) of the container, and is closed, on the opposite side to the base portion (2, 12), by a disk-shaped member (15); applying a cap (8) to the neck portion (3, 13); making a cut (16) along the periphery of the disk-shaped member (15) and on the side facing the pour opening (5); and joining the disk-shaped member (15), by adhesion, to a portion (10) of the cap (8) superimposed on the disk-shaped member, so that the disk-shaped member (15) defines a layer of gas-barrier material of the cap (8).
Patent CA-2636803-A1 (CA)
Title: Dental composites with a low shrinkage tension and high flexural strength
Inventor: DIEFENBACH CHRISTINE
IPC: A61K6/893
Filed: 2008-07-03
Abstract: Dental composite materials based on (meth)acrylate, as described in claim 1, exhibit a proportion of TCD monomers in the total composition of 1-15 % by weight and the quotient of flexural strength/shrinkage tension is at least 35.
Patent CA-2637181-A1 (CA)
Title: Hot runner nozzle having split ring seal
Inventor: ADAS JAMES O
IPC: B29C45/27
Filed: 2006-09-12
Abstract: An apparatus for injection molding wherein melt is conveyed to a gate (40) in fluid communication with at least one mold cavity (16) comprises a nozzle (20) for conveying melt, the nozzle having an inlet (28) for admitting melt, at least one outlet (30) for directing melt to mold cavities and received within a recess of the gate, a nozzle body having a passage (32) therethrough for conveying melt from the inlet to the outlet, and at least one split ring seal (36) received in a groove (38) in the exterior of the nozzle body (34) so as to be displaceable relative to the associated groove, the split ring seal having an outside perimeter for contacting the surface of the recess (42) of a gate, the split ring seals maintaining separation of the periphery of the nozzle body from the surface of the recess with the outlet positioned within the recess. Each split ring seal advantageously comprises overlapping end segments abuttingly engaged with the outlet positioned within the recess.
Patent CA-2638388-A1 (CA)
Inventor: NEWBOLD RONALD C JR
IPC: G01R31/36
Filed: 2008-07-30
Abstract: A lighting device including a test device for testing the proper operation of a primary and a secondary power supply alternatively providing electrical power to the light. The test device is attached to a bracket using a single fastener such as a nut and the bracket is attached to a receptacle for the light using a different single fastener, such as a pop- rivet or screw.
Patent CA-2647760-A1 (CA)
Inventor: MESTERS CAROLUS MATTHIAS ANNA MARIA
IPC: B01J23/10
Filed: 2006-04-04
Abstract: A process for reducing the total acid number (TAN) of a liquid hydrocarbonaceous feedstock, wherein the feedstock is contacted, in the presence of a hydrogen-containing gas and at a temperature in the range of from 200 to 400 °C and at elevated pressure, with a catalyst comprising an oxide of a metal of Column 3 or 4 of the Periodic Table of Elements or of a lanthanide, which catalyst is essentially free of Column 5 to 10 metals or compounds thereof, to obtain a liquid hydrocarbonaceous product with a reduced total acid number.
Patent CA-2649105-A1 (CA)
Inventor: WEISS MICHAEL J
IPC: C07C41/16
Filed: 2006-04-10
Abstract: Ethoxylates and other alkoxylates are made in an efficient manner by reacting an organic bromide with a diol in the presence of a metal oxide. An integrated process of bromide formation, alkoxylate synthesis, metal oxide regeneration, and bromine recycling is also provided.
Patent CA-2649617-A1 (CA)
Title: Methods, systems and apparatus for monitoring and/or generating communications in a communications network
Inventor: PARSONS BRIAN
IPC: H04L12/26
Filed: 2008-02-07
Abstract: A module for use in a communications network in which a plurality of signals are transmitted between respective first and second nodes, the module having an engine for receiving the plurality of signals over the network, for extracting protocol data therefrom and for providing the extracted protocol data to an analyser; and a processor for controlling operation of the engine and analyser. The invention also provides an apparatus for generating communications, systems including the module and/or the apparatus, and corresponding methods.
Patent CA-2650895-A1 (CA)
Title: Cylinder head structure in four-cycle engine
Inventor: AZUMAGAKITO ISAO
IPC: F01L1/18
Filed: 2009-01-23
Abstract: To achieve further reduction in size and weight of a cylinder head in a four--cycle engine having a connection surface formed on the cylinder head to connect a head cover set so as to follow along a plane that is inclined so as to be spaced further away from a cylinder block toward a first side wall in which an intake port is disposed relative to a second side wall in which an exhaust port is disposed. A camshaft holder having a semi-circular bearing portion and integrally connected to a first side wall is integrally formed on a cylinder head in a protruding condition so as to protrude from a connection surface as viewed from an axial direction of a camshaft. An intake port is disposed in the first side wall such that an upstream end thereof is disposed at the same position as that at which part of the bearing portion is disposed in a direction along an axis of a cylinder bore. An exhaust valve has a stem end 43a disposed at a position protruding from the connection surface as viewed in a direction along the axial direction of a camshaft.
Patent CA-2653338-A1 (CA)
Inventor: GROAT JEANNA
IPC: A23L19/00
Filed: 2007-05-24
Abstract: The present invention provides a transgenic corn event MON89034, and cells, seeds, and plants comprising DNA diagnostic for the corn event. The invention also provides compositions comprising nucleotide sequences that are diagnostic for said corn event in a sample, methods for detecting the presence of said corn event nucleotide sequences in a sample, probes and primers for use in detecting nucleotide sequences that are diagnostic for the presence of said corn event in a sample, growing the seeds of such corn event into corn plants, and breeding to produce corn plants comprising DNA diagnostic for the corn event.
Patent CA-2653351-A1 (CA)
Title: Wind turbine monitoring
Inventor: VOLANTHEN MARK
IPC: G01L25/00
Filed: 2009-02-10
Abstract: A method of detecting the formation of ice on the blades of a wind turbine 1 . The wind turbine has at least one turbine blade 2 mounted to a rotor and provided wit h at least a first strain sensor 4 for measuring mechanical strain of the turbine blade. The method comprises detecting changes in an output signal of the strain sensor 4 due t o changes in the mass of the turbine blade 2 caused by the formation of ice on the turbin e blade.
Patent CA-2654324-A1 (CA)
Title: Hiv-1 clade a consensus sequences, antigens, and transgenes
Inventor: JACKSON NICHOLAS
IPC: A61K39/12
Filed: 2007-06-04
Abstract: The present invention relates to consensus nucleotide and protein sequences for HIV- 1 Clade A antigens, and to nucleotide and protein sequences for Clade A antigens from circulating HIV-I field isolates wherein the antigen sequences are closely related to the these consensus sequences. In a preferred embodiment, the present invention relates to HIV-I Clade A transgenes that are derived from such sequences, and that encode either HIV-I Clade A Gag, Pol (RT and Int), and Nef (referred to as "GRIN"), HIV-I Clade A Gag, RT, and Nef (referred to as ("GRN"), or HIV-I Clade A Env. The invention also relates to vectors containing such transgenes, including in preferred embodiment, adenovirus vectors containing such transgenes. The invention also relates to immunogenic compositions comprising the HIV-I Clade A antigens, nucleotide sequences, vectors, or transgenes of the invention, and to methods of generating an immune response against HIV in a subject by administering an effective amount of such immunogenic compositions.
Patent CA-2654428-A1 (CA)
Inventor: ENOCH DUARD W
IPC: A01K63/00
Filed: 2006-11-10
Abstract: An aquarium cleaning device having an inner component (10) with a plate (16 ) employing a cleaning surface (30) and an alternative cleaning element (36) operative on a second surface opposite the cleaning surface. A magnetic element (28, 20) is carried by the plate and means for providing orienting buoyancy (24, 26, 28) is carried adjacent one end of the plate. An outer component (12) has a body (38) with a surface for engaging the exterior of an aquarium wall. A second magnetic element (40, 42) is carried by the body such that the body is positionable for magnetic attraction between the magnetic elements with the cleaning surface adjacent the aquarium wall or with the second surface adjacent the aquarium wall. By moving the body between the first and second positions , the inner component is flipped within the aquarium to alternate the cleaning elements.
Patent CA-2654904-A1 (CA)
Inventor: TREES GREGORY
IPC: B05B5/16
Filed: 2006-08-08
Abstract: A cartridge (20) for a handheld electrohydrodynamic (EHD) spraying device (10) and a spraying device incorporating the cartridge (20). The cartridge (20) is disposable, and can contain therapeutic products. The device includes a wetted lead screw (40) with a compliant seal (70), where the placement of the seal (70) relative to the screw inhibits leakage during both cartridge use and storage. A frame disposed within the cartridge (20) acts as a load-transferring mechanism for the weight of the cartridge (20) to a handle (26) of the spraying device (10).
Patent CA-2655951-A1 (CA)
Inventor: THOMPSON DENNIS
IPC: A01B63/22
Filed: 2009-02-24
Abstract: An assembly for facilitating steering of an agricultural implement linkable to a work vehicle is disclosed. The assembly comprises at least a first ground-engaging wheel to engage a ground surface below a frame of the agricultural implement to support the frame above the ground surface. The assembly further comprises a positioning system for receiving a positioning signal from a positioning source. The positioning system determines a current position of the agricultural implement from at least the positioning signal, and the positioning system generates a control signal derived from the current position of the agricultural implement. The assembly further comprises a steering cylinder connected to the first ground-engaging wheel.  The steering cylinder operatively connects to the positioning system to steer the first ground-engaging wheel based on the control signal.
Patent CA-2657487-A1 (CA)
Inventor: SHIN BRIAN J
IPC: G06F15/16
Filed: 2006-07-07
Abstract: A web-based hosted solution through which application developers create, manage and monitor application usage analytics in an online manner. Preferably, an application under test is one of : application software, a script-enabled web application, or a rich Internet application (RIA). During the development process, a usage monitoring API is integrated into the application and the application is deployed. As users interact with the application, a log file is generated, typically in one of two ways. If the application is able to write to a local file system (in the user's machine), usage information is gathered in a log file local to the deployed application and then dispatched to an upload server for processing in a batch manner. If the application is not able to write to the user machine's local file system, the usage information is sent to a remote logging server, preferably on a just-in-time basis, and then the log file is generated on the logging server. In either case, preferably the usage information that is tracked comprises "features", "faults" and "failures" of the application, independent of platform, location, and number of deployed application instances.
Patent CA-2658731-A1 (CA)
Inventor: KRALLINGER RUPERT
IPC: B27D5/00
Filed: 2007-07-30
Abstract: The present invention provides an apparatus (10) for producing and/or processing panels, comprising a transporting arrangement for transporting panels along a transporting path and a processing arrangement (12) for processing the panels as they are moved by the transporting arrangement, wherein the transporting arrangement comprises two double-belt conveying means (14, 16) each with a top endless belt (36) and a bottom endless belt (42), which each have a transporting strand (38, 40) essentially parallel to the transporting path and are each deflected by deflecting arrangements (24, 26, 28, 30) at the two ends of the transporting strand (38, 40), wherein the top endless belts (36) are in contact with the top side of a panel which is to be transported and the bottom endless belts (42) are in contact with the panel on its bottom side, and wherein at least one of the endless belts (36, 42) has its transporting strand (38, 40) guided by means of a plurality of guide rollers (48) arranged between the deflecting arrangements (24, 26, 28, 30).
Patent CA-2658889-A1 (CA)
Inventor: SPIVACK SCOTT DAVID
IPC: G06Q40/00
Filed: 2007-07-10
Abstract: An analysis system processes financial transactions data for compliance with a payment program, such that the processing involves receiving data relating to a set of financial transactions that have been authorized by a payment processing system, and determining if one or more of the authorized financial transactions will be subjected to further processing, wherein the further processing operates on the received data and identifies authorized financial transactions that may be out of compliance with transaction rules of the payment program.
Patent CA-2659950-A1 (CA)
Inventor: BIAGIOLI NICO
IPC: F23D14/64
Filed: 2008-07-25
Abstract: Gas burner provided with a plurality of concentric flame crowns, and comprising a first central burner to supply a peripheral flame ring, a second annular burner surrounding said central burner at a defined distance and able of supplying at least a respective peripheral ring, a burner body apt to be mounted on the surface of a cooking hob, a first gas inlet in communication with said body, a first vertical gas injector, said central burner being provided with a first chamber for the diffusion of the air/gas mixture, a second gas inlet in communication with said body, wherein said second annular burner is provided with two separate chambers for the diffusion of said mixture, wherein said second gas inlet is in communication with said two separate chambers through suitable injection and conveying means, which comprise two distinct injectors in communication with said second gas inlet, and two respective horizontal Venturi pipes each of which being able of supplying with said air/gas mixture a respective of said two diffusion chambers; these are physically separate and not in communication to each other. Said two horizontal and separate injectors are placed on the same end position of said second gas inlet.
Patent CA-2661837-A1 (CA)
Inventor: MILLER ROBERT A III
IPC: D06B5/08
Filed: 2007-08-28
Abstract: A method is provided for conditioning a tubular knitted fabric. The method includes the step of placing on a supported member a tubular knitted fabric formed of yarns, the yarns having fibers of a high cotton content. The layers of the fabric are arranged in overlying layered relation, each layer having an outer surface. The fabric is traversed at a preselected rate while subjecting the outer surfaces of the overlying layers to jets of fluid at pressures of about 40 bar absolute or lower. The fibers forming the overlying layers do not interlock the overlying layers and are separable by subsequent fabric finishing or laundering.
Patent CA-2663116-A1 (CA)
Inventor: HONIGBERG LEE
IPC: A61K31/519
Filed: 2006-12-28
Abstract: Disclosed herein are compounds that form covalent bonds with Bruton's tyr osine kinase (Btk). Also described are irreversible inhibitors of Btk. Metho ds for the preparation of the compounds are disclosed. Also disclosed are ph armaceutical compositions that include the compounds. Methods of using the B tk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseas es or conditions.
Patent CA-2666662-A1 (CA)
Inventor: DIMITRATOS SPIROS D
IPC: G01N33/566
Filed: 2007-10-11
Abstract: This invention provides methods and compositions for using chemosensory proteins derived from invertebrates to bind or detect specific compounds. Applications include use as detector elements in biosensors or other sensory devices and purification or concentration devices. Examples of proteins involved in the chemosensory pathway include odorant binding proteins (OBPs), sensory appendage proteins (SAPs), orthologs of the Drosophila melanogaster Takeout protein (TOLs), odorant or gustatory receptors (ORs, GRs, or collectively GPCRs), other serpentine receptors, and odorant degrading enzymes (ODEs). These classes of proteins participate in both the olfactory and gustatory sensory systems in invertebrates. The invention provides methods and compositions for identifying analytes such as effectors, binding partners, or other molecules that interact with the proteins involved in the chemosensory pathway. The method for sensor applications consists of linking a detection mechanism with one or more invertebrate chemosensory protein(s) so that a measurable signal is generated when an analyte such as ligand or binding partner to the chemosensory protein(s) is present. The method for the purification applications involves utilizing chemosensory proteins capable of isolating specific analytes in complex mixtures. Thus, the invention provides methods to identify the presence of specific analytes, and also to exclude or include specific analytes from a process or mixture.
Patent CA-2666801-A1 (CA)
Inventor: ALVARES ANTONIO CARLOS TEIXEIRA
IPC: B65D43/06
Filed: 2007-08-18
Abstract: A closure arrangement for cans and pots comprising a tubular body (1) having a side wall (10) whose upper edge (10a) defines a seat for a lid (20). The upper edge (10a) comprises a peripheral annular flange (11) carrying, in a free outer edge, a continuous rib (12) with a cross-section contour comprising two opposite circle arc portions (12a), with curvature centers disposed in the same plane (P) orthogonal to the axis of the tubular body (1), the lid (20) being inferiorly provided with a continuous circumferential groove (24) to be seated against the respective circle arc portions (12a) of the continuous rib (12), so as to axially lock the lid (20) in the tubular body (10). An annular gasket (30) is carried by one of the parts of peripheral annular flange (11) and lid (20), to be pressed by the other of said parts upon closing the lid.
Patent CA-2667367-A1 (CA)
Inventor: HILEMAN BLAIN
IPC: B65D19/00
Filed: 2007-09-25
Abstract: Foamed plastic structures that include one or more foamed plastic bodies containing a polymer matrix that includes one or more polymers formed by polymerizing a monomer mixture that includes vinyl aromatic monomers and divinyl aromatic monomers. The structures formed can include, as non-limiting examples, pallets, containers, stackable containers, produce boxes, seafood shipping containers, geofoam blocks, and insulated concrete forms.
Patent CA-2667704-A1 (CA)
Title: Security element
Inventor: VOIT MAX
IPC: B42D15/00
Filed: 2007-10-26
Abstract: A security element or a security document provided therewith comprises a substrate (1), a recess (3) which passes through the substrate, and an imprint (4) which adjoins the recess (3) and with the recess completes an information-conveying symbol or pattern (~20"). At least the recess (3) is covered by a film (5). A security feature (6), which can be visually checked and is preferably provided at least partially on the film (5), conveys a colour impression which varies due to an external stimulus and reverses on its own accord, and is arranged relative to the information-conveying symbol or pattern (~20") such that the symbol or pattern (~20") is obscured without the stimulus and the visual recognizability of the symbol or pattern is facilitated by way of the stimulus.
Patent CA-2669951-A1 (CA)
Title: Protein particles
Inventor: SOMMER-KNUDSEN JENS
IPC: C07K14/00
Filed: 2007-12-03
Abstract: The invention relates to a protein particle comprising chimeric protein having an aggregating part capable of forming or aggregating into a substantially insoluble protein particle when expressed by a cell; and a functional part capable of binding to, or being bound by, a target compound. Affinity matrixes comprising the protein particle are also provided.