baber/WOPTO huggingface dataset:
Patent EP-4168414-A1 (EP)
Inventor: HADARI YARON R
IPC: A61P37/00
Filed: 2021-06-17
Abstract: L'invention concerne des procédés et des compositions pour le traitement de cancers, de maladies inflammatoires, de rasopathies, et d'une maladie fibrotique impliquant une signalisation de la superfamille Ras aberrante par la liaison de composés au domaine de liaison GTP de protéines de la superfamille Ras comprenant, dans certains cas, K-Ras et ses mutants, et un procédé de dosage de telles compositions.
Patent EP-4173079-A1 (EP)
Title: Shaped rechargeable battery electronic interconnect
Inventor: ZHAO HAILIANG
IPC: H01M50/54
Filed: 2021-06-25
Abstract: Devices and methods disclosed herein relate to forming superior mechanical and electrical connections between stacks of foils such as those used in electrochemical cells. The connections described herein use multiple weld types and choice of materials to promote electrical and mechanical connectivity using separate weld types.
Patent EP-4185473-A1 (EP)
Inventor: KELLY JIM
IPC: B60G17/016
Filed: 2021-07-21
Abstract: Des aspects de la présente invention se rapportent à un procédé et à un système de commande d'une suspension active d'un véhicule comprenant une carrosserie de véhicule et une pluralité de roues, ce système de commande comportant au moins un dispositif de commande, le système de commande étant conçu pour : recevoir des informations indiquant une demande d'entrée/sortie de passagers et/ou de chargement; recevoir des informations indiquant que l'entrée/sortie va se produire lorsque le véhicule est sur une surface en pente; et commander la suspension active pour réduire l'angle de la carrosserie du véhicule par rapport à l'horizontale, pour l'entrée/sortie sur la surface en pente.
Patent EP-4181934-A1 (EP)
Title: Phosphate de zirconium cristallin destiné à être utilisé en thérapie, composition pharmaceutique et utilisation correspondante
Inventor: BLUECHEL CHRISTIAN GERT
IPC: A61K33/24
Filed: 2021-07-21
Abstract: La présente divulgation concerne un phosphate de zirconium cristallin et une composition pharmaceutique comprenant du phosphate de zirconium cristallin et éventuellement un ou plusieurs agents thérapeutiquement efficaces pour une utilisation en thérapie. La divulgation concerne également l'utilisation de phosphate de zirconium cristallin dans la fabrication d'une composition pharmaceutique pour le traitement d'un patient présentant des taux anormalement élevés d'une ou de plusieurs toxines.
Patent EP-4185417-A1 (EP)
Inventor: JANSEN THOMAS JAN HERBERT
IPC: B21D37/20
Filed: 2021-07-16
Abstract: The invention relates to a clamping system for a press brake, the clamping system comprising an elongate beam comprising a receiving space for receiving a part of a bending tool, the elongate beam having at least two cavities formed therein, wherein each of the at least two cavities has an opening to the exterior of the elongate beam. The clamping system is characterized in that the at least two cavities are interconnected internally. The invention also relates to a press brake comprising such a clamping system, and a method of manufacturing an elongate beam for such a clamping system. The method comprises amongst others a step of providing a fluid connection to each of at least two cavities in the elongate beam by interconnecting the at least two cavities by machine from inside at least one of the at least two cavities.
Patent EP-4188064-A1 (EP)
Inventor: PLÖGER WERNER
IPC: A01D23/02
Filed: 2021-07-21
Abstract: The invention relates to a cutting device (40) for cutting plants. The cutting device comprises at least one cutting unit (41) which has at least one probe element (21), fastened to a holding element (13), for determining an extent of a plant, at least one cutting element (22), fastened to a further holding element (11), for cutting the plant depending on the extent, and at least two frame coupling elements (4, 6). Here, at least one of the holding elements (11, 13) is coupled to a cutting device frame (1) by the frame coupling elements (4, 6). The holding elements (11, 13) are arranged movably relative to one another. The cutting device comprises an adjusting device (42) which is configured to adjust the holding elements (11, 13) relative to one another independently of a movement of at least one of the holding elements (11, 13) relative to the cutting device frame (1).
Patent EP-4100886-A1 (EP)
Title: Neural network unit
Inventor: SONG SEUNG-HWAN
IPC: G06N3/063
Filed: 2021-02-02
Abstract: A neural network unit is disclosed. This neural network unit includes: a main synapse array having a plurality of main synapses in rows and columns of the array, each connected to one or more bit lines associated with the network unit; a main synapse driver for applying an input to one or more of the main synapses in a row; a reference synapse for generating a particular output to a selected one or more associated bit lines; and, a sensing circuit for controlling the reference synapse in generating the output in a selected column of the array, wherein the sensing circuit is adapted to infer an output from one or more main synapses in a selected column by: defining a reference range of the output to be generated by reference synapse; setting a reference level from the reference range; activating a selected reference synapse to implement the reference level that is set or adjusted; and comparing an output from the main synapse summed with the output from the activated reference synapse in the selected column with a threshold value predetermined.
Patent EP-4103219-A1 (EP)
Inventor: YANG ZHENG
IPC: A61P31/12
Filed: 2021-02-10
Abstract: Provided is use of IL-22 dimer in prevention or treatment of virus-induced organ injury or failure, such as lung injury or failure, sepsis, septic shock, or multiple organ dysfunction syndrome (MODS) associated with virus infection.
Patent EP-4188939-A1 (EP)
Inventor: BODDIN JANA
IPC: C07K14/005
Filed: 2021-07-30
Abstract: The present invention generally relates to the field of adenoviruses and adenoviral vectors that can be used as vaccines and gene therapy vectors. More specifically, the present invention relates to an adenovirus or an adenoviral vector that comprises a mutated DNA-binding protein that inhibits adenoviral DNA replication in a cell infected with a virus expressing said protein. The invention further relates to a nucleotide sequence encoding the mutated DNA-binding protein. In another aspect, the invention provides pharmaceutical compositions, vaccines and cells that comprise the mutated protein, a nucleotide sequence encoding same, or a modified adenovirus or adenoviral vector comprising any of those. The invention also relates to the use of the mutated protein, a nucleotide sequence encoding the same, or an adenovirus or recombinant adenoviral vector comprising any of those for the preparation of a vaccine.
Patent EP-4107180-A1 (EP)
Title: Designer peptides and proteins for the detection, prevention and treatment of coronavirus disease, 2019 (covid-19)
Inventor: WANG CHANG YI
IPC: A61P11/00
Filed: 2021-02-19
Abstract: The present disclosure is directed to a relief system for the effective detection, prevention, and treatment of COVID-19, including (1) serological diagnostic assays for the detection of viral infection and epidemiological surveillance, (2) high-precision, site-directed peptide immunogen constructs for the prevention of infection by SARS-CoV-2, (3) receptor-based antiviral therapies for the treatment of the disease in infected patients, and (4) designer protein vaccine containing S1-RBD-sFc. The disclosed relief system utilizes amino acid sequences from SARS-CoV-2 proteins as well as human receptors for the design and manufacture of optimal SARS-CoV-2 antigenic peptides, peptide immunogen constructs, CHO-derived protein immunogen constructs, long-acting CHO-derived ACE2 proteins, and formulations thereof, as diagnostics, vaccines, and antiviral therapies for the detection, prevention, and treatment of COVID-19.
Patent EP-4116096-A1 (EP)
Inventor: OKUBO KATSUYUKI
IPC: B65D65/40
Filed: 2021-03-02
Abstract: Provided are a liquid-packaging carton material and a liquid-packaging carton each suitable for sealing of a joint portion by an ultrasonic vibration sealing system. The liquid-packaging carton material includes: a paper base material layer (layer A); a thermoplastic resin layer containing a polyethylene resin as a main component (layer B) serving as an outermost layer, which is laminated on a front surface of the paper base material layer (layer A); and at least: a thermoplastic resin layer containing a polyethylene resin as a main component (layer C); a barrier layer (layer D); an adhesive resin layer (layer E); and a thermoplastic resin layer containing a polyethylene resin as a main component (layer F) serving as an innermost layer, which are laminated on a back surface of the paper base material layer (layer A) in the stated order from a back surface side, wherein a thermoplastic resin for forming the thermoplastic resin layer (layer F) has a melt mass-flow rate higher than a melt mass-flow rate of an adhesive resin for forming the adhesive resin layer (layer E).
Patent EP-4211702-A1 (EP)
Title: A method and device for providing an automated prediction of a change of a state of fatigue of a subject carrying out a visual task
Inventor: GAO YI
IPC: G16H50/30
Filed: 2021-08-30
Abstract: This computer-implemented method for providing an automated prediction of a change of a state of fatigue of a subject carrying out a visual task involving any kind of visual content comprises: providing a plurality of input data, relating to the subject, to a fatigue state change predictive model, wherein the plurality of input data comprises at least one subjective measurement relating to the subject and/or at least one objective measurement relating to the subject and/or at least one other subject-related datum; obtaining, by a processor implementing the model, a value representing a level of change of the state of fatigue of the subject.
Patent EP-4121020-A1 (EP)
Title: Cannabinoid compositions
Inventor: PENNER REINHOLD
IPC: A61K36/185
Filed: 2021-03-19
Abstract: Described herein are pharmaceutical compositions comprising cannabinoids. In some embodiments, such compositions are useful for the treatment of inflammatory, autoimmune diseases or disorders, cancer, or neurodegenerative diseases. Further provided herein are pharmaceutical compositions comprising combinations of cannabinoids possessing entourage effects.
Patent EP-4204893-A1 (EP)
Title: Light guide display assembly for providing expanded field of view
Inventor: AMIRSOLAIMANI BABAK
IPC: G02B27/01
Filed: 2021-08-26
Abstract: A device includes one or more light guides. The device also includes a first in-coupling element configured to couple a first light having a first input field of view ("FOV") into a first light guide, and a second in-coupling element configured to couple a second light having a second input FOV into a second light guide. The device also includes a first out-coupling element configured to couple the first light out of the first light guide as a first output light having a first output FOV, and a second out-coupling element configured to couple the second light out of the second light guide as a second output light having a second output FOV substantially non-overlapping with the first output FOV. A combination of the first output FOV and the second output FOV is larger than at least one of the first output FOV or the second output FOV.
Patent EP-4125429-A1 (EP)
Inventor: ROBERTSON DAN E
IPC: A23L27/20
Filed: 2021-03-24
Abstract: Structured food compositions, such as meat analogue compositions, which include protein products from microorganisms, such as microorganism-derived protein hydrolysates, are described. Methods of making such products are also described. Flavor enhancer compositions that contain heme-containing polypeptides, such as flavohemoglobin, from microorganisms, and food compositions, such as meat analogue compositions that include the heme-containing flavor enhancer compositions, are also described.
Patent EP-4217346-A1 (EP)
Inventor: OEHLRICH DANIEL
IPC: C07D237/28
Filed: 2021-09-23
Abstract: L'invention concerne de nouveaux composés destinés à être utilisés en tant qu'inhibiteurs de la production d'inflammasome NLRP3, lesdits composés étant tels que définis par les composés de formule (I) et les nombres entiers R 1 , R 2  et R 3  étant tels que définis dans la description, et où les composés peuvent être utiles en tant que médicaments, par exemple pour une utilisation dans le traitement d'Une maladie ou d'un trouble qui est associé à l'activité de l'inflammation de NLRP3.
Patent EP-4225164-A1 (EP)
Title: Hand-held shaft-type surgical instrument
Inventor: RUISZ MARTIN
IPC: A61B17/16
Filed: 2021-09-29
Abstract: The invention relates to a hand-held sliding shaft-type (2) surgical instrument, comprising a shaft (5), in which a longitudinal groove (7) is formed extending over the length of the shaft, and a slide (6), which is movably mounted in the longitudinal groove (7) and the relative movement of which in the longitudinal groove (7) is at least partly guided by at least one shaft (5) connecting piece (8) which constricts the longitudinal groove (7) in the width direction of the groove, wherein the shaft (5) has a cleaning recess (10) in the region of the connecting piece (8) in the longitudinal direction, said cleaning recess forming a radial through-opening which opens into the longitudinal groove (7) from the groove base side.
Patent EP-4201093-A1 (EP)
Inventor: WONG SHIN HORNG
IPC: H04W74/08
Filed: 2021-09-24
Abstract: Un procédé de fonctionnement d'un dispositif de communication comprend une étape consistant à déterminer que le dispositif de communication peut transmettre des données par l'intermédiaire de ressources de communication d'un canal sans licence d'une interface d'accès sans fil qui est partagé dans le temps avec un équipement d'infrastructure d'un réseau de communication sans fil et/ou un ou plusieurs autres dispositifs de communication qui peuvent également transmettre dans le canal sans licence. La transmission des données par le dispositif de communication est organisée dans le temps en fonction d'une période de trame fixe (FFP) contenant un temps d'occupation de canal (COT) permettant de transmettre les données et une période d'inactivité. Le dispositif de communication peut transmettre les données sur le canal sans licence en détectant que ni l'équipement d'infrastructure ni lesdits un ou plusieurs autres dispositifs de communication ne transmettent sur le canal sans licence en tant que partie d'une phase d'accès au canal en concurrence. Le procédé comprend également les étapes consistant à : déterminer qu'une ou plusieurs parties d'un temps d'occupation de canal d'une période de trame fixe sont inutilisées par le dispositif de communication transmettant au moins une partie des données ; et libérer lesdites une ou plusieurs parties du canal sans licence fournissant des ressources de communication inutilisées destinées à être utilisées par l'équipement d'infrastructure et/ou lesdits un ou plusieurs autres dispositifs de communication pour transmettre des signaux. Il en résulte une organisation dans laquelle des ressources de communication inutilisées d'un canal sans licence partagé dans le temps peuvent être libérées par un dispositif de communication ou un équipement d'infrastructure.
Patent EP-4226073-A1 (EP)
Inventor: PHILIPPE ANTOINE
IPC: F17C3/02
Filed: 2021-09-30
Abstract: The invention relates to a sealed and thermally insulating tank. The primary insulating barrier (4) of the tank comprises a plurality of insulating blocks (10) positioned next to one another, each insulating block comprising a bottom plate (11) and a thermally insulating foam block (12) disposed on the bottom plate (11), the bottom plate (11) of each insulating block (10) extending beyond the thermally insulating foam block (12) so that a space is created each time between the thermally insulating foam block (12) and the thermally insulating foam block of an adjacent insulating block. The primary insulating barrier (4) further comprises a plurality of bridging elements (20), wherein each bridging element (20) is arranged in one of the spaces between the thermally insulating foam blocks (12) of two adjacent insulating blocks (10), is secured to an inner face of the bottom plates (11) of the two adjacent insulating blocks, and covers part of said inner faces.
Patent EP-4208515-A1 (EP)
Title: Uv/moisture dual cure composition with enhanced substrate adhesion
Inventor: LIU JUNYING
IPC: C09D183/08
Filed: 2021-08-30
Abstract: A composition contains: (a) a first organopolysiloxane with an average of 2 or more mercaptoalkyl groups per molecule and that is free of alkenyl functionality; (b) a second organopolysiloxane with an average of one or more alkenyl group and one or more alkoxy group per molecule; (c) a tetraalkoxy silane; (d) an ultraviolet light photoinitiator; and (E) a condensation catalyst; where the concentration of the first and second organopolysiloxanes are such that the molar ratio of mercaptoalkyl groups to alkenyl groups is in a range of 0.4 to 3.0.
Patent EP-4211430-A1 (EP)
Title: Appareil de pesée pour fauteuil roulant
Inventor: HALL RICHARD
IPC: G01G19/02
Filed: 2021-09-10
Abstract: L'invention concerne un appareil (100) pour peser un fauteuil roulant, l'appareil étant pliable entre une position de pesée et une position pliée pour faciliter le transport et le stockage.
Patent EP-4222487-A1 (EP)
Inventor: DEMMA ALESSANDRO
IPC: G01N29/14
Filed: 2021-10-01
Abstract: Un capteur d'émission acoustique (AE) comprend un élément de détection de vibrations et un amplificateur mécanique (2). L'amplificateur mécanique se présente sous la forme d'une plaque métallique, ladite plaque métallique présentant une largeur au moins 2,5 fois supérieure à toutes les largeurs associées à l'élément de détection de vibrations, et une zone au moins (5) fois supérieure à toutes les zones correspondantes associées à l'élément de détection de vibrations. L'amplificateur mécanique (2) est couplé dynamiquement à l'élément de détection de vibrations, en amont de l'élément de détection de vibrations. De cette manière, la largeur et la zone 4, 5 de l'amplificateur mécanique (2) sont spécifiées de façon à augmenter un rapport signal sur bruit d'un signal AE (6) émis en sortie par le capteur AE (10) en réponse à une émission acoustique (7) générée par une source AE cible (8). Le capteur AE (10) présente ainsi une sensibilité améliorée à la source AE cible (8).
Patent EP-4138817-A1 (EP)
Inventor: BROWN MILTON L
IPC: A61K38/54
Filed: 2021-04-21
Abstract: A method of treating a viral infection may include administering a pharmaceutical composition including a renin- angiotensin system (RAS) modulator to a subject in need thereof to mitigate a cellular and organic impact of the viral infection. The mitigation may include inhibiting reactive oxygen species, inhibiting cytokine release, upregulating angiotensin- converting enzyme 2 (ACE2), and/or downregulating angiotensin II receptor type 1 (ATI). The renin-angiotensin system modulator may include various combinations of an angiotensin receptor blocker (ARB), angiotensin (1-7), an HMG-CoA reductase inhibitor, an angiotensin-converting- enzyme (ACE) inhibitor, 3,3 '- diindolylmethane (DIM), indole-3-carbinol (I3C), and/or pirfenidone (PFD). In addition, at least one of the angiotensin receptor blocker, the angiotensin (1-7), the HMG-CoA reductase inhibitor, the angiotensin-converting- enzyme inhibitor, 3,3'- diindolylmethane, indole-3-carbinol, or pirfenidone may be linked to an antioxidant.
Patent EP-4236789-A1 (EP)
Inventor: HAYS ARNAUD
IPC: A61B5/11
Filed: 2021-10-27
Abstract: The invention relates to a method for neuromuscular characterisation of at least one lower and/or upper limb of an individual using a measuring bench. Said method comprises a step (E1) of placing the individual in the measuring bench, a step (E5) of unlocking the seat of the individual, a step (E6) of receiving the individual on a force platform, a step (E7) of pushing the individual on the force platform, a step (E8) of acquiring signals and a step (E10) of processing data from the acquired signals. In a step (E11), the carriage is damped and the seat is subsequently locked in a step (E12) at its end position after the pushing step and is then gently returned to a test position.
Patent EP-4146925-A1 (EP)
Title: Multi-mode propulsion system
Inventor: JOHANSEN CRAIG
IPC: B64D27/00
Filed: 2021-05-05
Abstract: The present invention provides a multimode propulsion system, comprising at least one propellant ejector system, a high speed fluid ejection nozzle coupled to a propellant supply provided in the engine, and a propellant-air mixing system comprising at least one fluid intake member having an inlet end and an outlet end, the inlet end being in fluidic communication with the fluid ejection nozzle to receive the propellant ejected from the nozzle.
Patent EP-4147355-A1 (EP)
Inventor: LI SHIFENG
IPC: H03M1/18
Filed: 2021-04-27
Abstract: An integrated circuit for controlling a sensor chip capable of sensing various materials includes a plurality of amplifier clusters, a plurality of analog multiplexers, and at least one analog-to-digital converter coupled the analog multiplexers and configured to generate digital code values representative of electrical signals. Each of the amplifier clusters include four amplifiers, each amplifier has a first input coupled to a sensor of the sensor chip, and a second input coupled to a programmable voltage reference. Each one of the analog multiplexers is coupled to one of the amplifier clusters and configured to selectively pass through an electrical signal to the at least one analog-to-digital converter.
Patent EP-4147154-A1 (EP)
Inventor: WAIBEL ALEXANDER
IPC: G10L15/00
Filed: 2021-04-02
Abstract: Computer systems and computer-implemented methods provide for interactive and incremental post-editing of real-time speech transcription and translation. A first component is automatic identification of potentially problematic regions in the output (e.g., transcription or translation) that are either likely to be technically processed badly or risky in terms of their content or expression. A second component is intelligent, efficient interfaces that permit multiple editors to correct system output concurrently, collaboratively, efficiently, and simultaneously, so that corrections can be seamlessly inserted and become part of a running presentation. A third component is incremental learning and adaptation that allows the system to use the human corrective feedback to deliver instantaneous improvement of system behavior down-stream. A fourth component is transfer learning to transfer short-term learning into long term learning if the modifications warrant long-term retention.
Patent EP-4244560-A1 (EP)
Title: Freeze dryer and method for freeze drying
Inventor: VAN DER WEL PETER GERARDUS JOSEPHUS
IPC: F26B5/04
Filed: 2021-11-12
Abstract: The invention relates to a freeze dryer, comprising: a freeze-drying chamber having an inlet for allowing material to be dried to be introduced into the freeze-drying chamber and configured for being evacuated at least partially; and a vacuum source in fluid communication with the drying chamber and configured for evacuating the freeze-drying chamber at least partially, wherein a vacuum fluid path is defined between the freeze-drying chamber and the vacuum source, wherein the freeze dryer further comprises a collecting filter configured for collecting dried material from the freeze-drying chamber, which collecting filter is arranged outside the freeze-drying chamber and within the vacuum fluid path between the freeze-drying chamber and the vacuum source.