Patent NZ-553119-A (NZ)
Title: Pharmaceutical formulation comprising an antibiotic, a triazole and a corticosteroid
Inventor: HUQ ABU
IPC: A61K31/4174
Filed: 2005-08-10
Abstract: Disclosed is a pharmaceutical composition for the treatment of an otic infection in an animal comprising an antibiotic, a triazole compound, a corticosteroid and at least one carrier. The composistion is in the form of a suspension. The antibiotic could be Orbifloxacin, Amoxicillin, Ampicillin, Ampicillin Trihydrate, Ampicillin Sodium, Apalcillin, Aspoxicillin, Azlocillin, Bacampicillin, Carbenicillin, Carbenicillin Sodium, Cariecillin, Carindacillin, Ciclacillin, Cloxacillin Sodium, Cloxacillin Benzathine, Dicloxacillin, Dicloxacillin Sodium, Flucloxacillin, Hetacillin, Lenampicillin, Mecillinam, Metampicillin, Methicillin, Mezlocillin, Nafcillin, Nafcillin Sodium, Oxacillin, Penicillic Acid, Penicillin G, Penicillin G Benzathine, Penicillin G Potassium, Penicillin G Sodium, Penicillin V, Phenethicillin, Phenethicillin Potassium, Piperacillin, Piperacillin Sodium, Pivampicillin, Sulbenicillin, Sultamicillin, Talampicillin, Ticarcillin, Cefaclor, Cefadroxil, Cefadroxil Monohydrate, Cefamandole, Cefamandole Lithium, Cefamandole Nanfate, Cefamandole Sodium, Cefazaflur, Cefazedone, Cefazolin, Cefazolin Sodium, Cefclidine, Cefdinir, Cefepime, Cefetamet, Cefixime, Cefluprenam, Cefmenoxime, Cefmetazole Sodium, Cefodizime, Cefonicid, Cefoperazone, Cefoperazone Sodium, Ceforanide, Cefoselis, Cefotaxime, Cefotaxime Sodium, Cefotiam, Cefozopran, Cefpimizole, Cefpimizole Sodium, Cefpiramide, Cefpirome, Cefpodoxime, Cefprozil, Cefquinome, Cefroxadine, Cefsulodin, Cefsulodin Sodium Hydrate, Ceftazidime, Ceftazidime Pentahydrate, Ceftezole, Ceftibuten, Ceftiolene,Ciprofloxacin, Danofloxacin, Enoxacin, Grepafloxacin, Levofloxacin, Lomefloxacin, Nalidixic acid, Norfloxacin, Ofloxacin, Sparfloxacin, Marbofloxacin, Ibafloxacin, Garenoxaein, T-3811M1, T-3811M4, T3811M6, Galifloxaein, Gemifloxaein, Moxifloxacin, Difloxacin, Rufloxacin, Pradofloxacin and Trovafloxacin mesylate, Ceftizoxime, Ceftriaxone, Ceftriaxone Disodium Salt, Ceftriaxone Sodium, Cefuroxime, Cefuzonam, Cephacetrile, Cephalexin, Cephaloridine, Cephalosporin C, Cephalothin, Cephalothin Sodium, Cephapirin, Cephapirin Sodium, Cephradine, Loracarbef, Cefbuperazone, Cefoxitin, Cefoxitin Sodium, Cefminox, Cefmetazole, Cefotetan, either alone or in combination with Beta Lactamase inhibitors such as Clavulanic Acid, Potassium Clavulanate, Sulbactam Lodopenicillanic acid, 6-Bromopenicillanic acid, Olivanic acids, and Tazobactam, Azithromycin, Brefeldin, Clarithromycin, Erythromycin, Erythromycin Estolate, Erythromycin Ethyl Succinate, Erythromycin Stearate, Josamycin, Kitasamycin Tulathromycin, Florfencol, Tulathromycin, Tilmicosin or an antibiotic of formula I where the variables are as defined in the specification. The triazole compound could be Voriconazole, Ketoconazole, Fluconazole, Itraconazole, Saperconazole, Neticonazole, Oxiconazole, Isoconazole, Sulconazole, Tioconazole or Posaconazole. The corticosteroid could be Mometasone, Mometasone Furoate, Mometasone Furoate Monohydrate, Dexamethasone, Butoxicart, Rofleponide, Budesonide, Deflazacort, Ciclesonide, Fluticasone, Beclomethasone, Loteprednol, Triamcinolone Betamethasone, Fluocinolone, Prednisone or Prednisolone.