baber/WOPTO huggingface dataset:
Patent NZ-612477-A (NZ)
Title: Hedgehog antagonists having zinc binding moieties
Inventor: CAI XIONG
IPC: C07D409/12
Filed: 2012-01-03
Abstract: Provided are benzimidazole and pyridine derivative compounds of the general formula (I) or (II), wherein the variables are as defined in the specification. Examples of the compounds include (E)-2-chloro-N-(4-chloro-3-(5-(3-(hydroxyamino)-3-oxoprop-1-enyl)pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide and 2-((3-(4-Chloro-3-(5-(dimethylamino)-1H-benzo[d]imidazol-2-yl)phenylcarbamoyl)-5-methoxybenzyl)(methyl)amino)-N-hydroxypyrimidine-5-carboxamide. The compounds contain zinc binding moieties and can inhibit histone deacetylase (HDAC) and the hedgehog pathway. The compounds may be useful in the treatment of cancer, psoriasis or macular degeneration.
Patent NZ-614579-A (NZ)
Title: A method of reducing biofilm formation on a surface
Inventor: SPURRELL LEON BRYAN
IPC: C23C24/04
Filed: 2012-08-21
Abstract: 614579 Disclosed is a method of reducing biofilm formation on a surface, the method comprising the steps of: a) providing particles of at least one material; and b) applying the particles from step a) to the surface in the presence in a liquid via at least one predetermined acoustic wave frequency to facilitate sonic impaction and adhesion of the particles onto the surface wherein at least one surface contour of the material is formed on the surface after step b) to reduce the formation of a biofilm on the surface over time. The surface is any part of a dairy farm milking system selected from the group consisting of: pipes, milking cups, inflations, claws, milk meter, hoses, vacuum lines, water lines and water troughs. The particles are selected from the group consisting of silicon dioxide (silica), silicon, silicone, silane, at least one precious metal and a combination thereof. The process produces a surface that under AFM looks like that shown in figure 1 with an alteration in the contour of the surface (1) at the nano-scale by application of nanoparticles to a dry surface in a liquid by creating a non-uniform pattern of uneven heights, shapes, lengths and spaces (2) to the surface (1) which are inhospitable to bacterial attachment and therefore biofilm growth.
Patent NZ-622007-A (NZ)
Title: Smoking article comprising a combustible heat source with a rear barrier coating
Inventor: DEGOUMOIS YVAN
IPC: A24D1/22
Filed: 2012-11-14
Abstract: A combustible heat source (4) with an airflow channel (16) and a non-metallic, non-combustible, gas-resistant barrier coating (14) for a tobacco heating e-cigarette is described. The barrier coating (14) prevents the migration of aerosol from the aerosol forming substrate (6) to the combustible heat source (4) and reduces the level of harmful or toxic smoke constituents. The barrier coating has an elemental metal or alloy content of less than 50 mole percent.
Patent NZ-625017-A (NZ)
Title: Method of making a foam
Inventor: SPEER DREW
IPC: C08J9/30
Filed: 2011-11-22
Abstract: A method of making a foam comprising the following steps. A mixture is created comprising (i) a first reactant comprising triglyceride having acrylate functionality, (ii) a second reactant comprising diacrylate, and (iii) a blowing agent. The mixture is expanded to create a froth. The first and second reactants of the froth are reacted to create the foam.
Patent NZ-702818-A (NZ)
Title: Stem cell factor inhibitor
Inventor: LUKACS NICHOLAS W
IPC: C07K16/00
Filed: 2012-01-10
Abstract: Disclosed is an anti-stem cell factor antibody that specifically binds to stem cell factor isoform b relative to stem cell factor isoform a or an antigen-binding antibody fragment that specifically binds to stem cell factor isoform b relative to stem cell factor isoform a.
Patent NZ-703127-A (NZ)
Title: Microwave curing of multi-layer coatings
Inventor: BÖHM SIVASAMBU
IPC: B05D7/14
Filed: 2013-07-03
Abstract: The present invention relates to a method for providing a coated strip, which comprises the steps of providing a metal or metal alloy strip, applying one or more coating layers on the metal or metal alloy strip and irradiating one or more of the applied coating layers with electromagnetic radiation, wherein one or more of the applied coating layers comprise dielectric particles capable of absorbing microwave radiation and wherein microwave radiation is used to selectively heat one or more of the coating layers containing the dielectric particles to dry and/or cure and/or sinter the coating layer.
Patent NZ-706393-A (NZ)
Title: Macrolide derivatives, preparation thereof and therapeutic use thereof
Inventor: BAURIN NICOLAS
IPC: C07H15/26
Filed: 2013-09-16
Abstract: The present invention relates to macrolide derivatives, and to the preparation and therapeutic use thereof. The compounds according to the present invention have substantial bacteriostatic and/or bactericidal antimicrobial activity, mainly on gram-positive microorganisms. The compounds also act on mycobacteria, especially against strains of sensitive Mycobacterium or Corynebacterium that are resistant to the first-line antibiotics and in the treatment of tuberculosis. In particular, the patent application relates to compounds of formula (I) below, and to a process for preparing them and to the therapeutic use thereof.
Patent NZ-707064-A (NZ)
Title: Method and systems for the delivery of oxygen enriched gas
Inventor: WILKINSON WILLIAM R
IPC: B01D53/047
Filed: 2013-10-14
Abstract: Known oxygen concentrator systems for delivering oxygen enriched gas to a user may fail to adequately account for erratic breathing patterns of the user. This may require artificial “blind periods” to be created when using known systems. The present invention comprises an oxygen concentrator apparatus configured to automatically measure the time between a plurality of successive breaths and determine an average breathing rate based on the time between each breath of the plurality of successive breaths, wherein the time between a penultimate breath and a last breath of the plurality of successive breaths is not used to determine the average breathing rate. In discarding information pertaining to the last measured breath from the determination of average breathing rate, the present invention provides a way to take into account a user’s erratic breathing patterns without the need to create artificial “blind periods”.
Patent NZ-709130-A (NZ)
Title: Self-supporting cable and combination comprising a suspension arrangement and such self-supporting cable
Inventor: EFRAIMSSON LARS
IPC: H01B9/00
Filed: 2013-11-25
Abstract: A self-supporting cable (2) comprising an outer portion (4) and an inner portion (6) is provided, as well as a combination of a self-supporting cable (2) and a suspension arrangement. The inner portion (6) comprises at least one insulated conductor (8) and the outer portion (4) comprises a first inner surface (10) and an external surface (12). The external surface (12) is arranged to engage with a suspension arrangement. The inner portion (6) comprises a first outer surface (16), the first outer surface (16) abutting against the first inner surface (10). The outer portion (4) comprises an outer layer (18) and a metal tape (20) adhered to the outer layer (18). The outer layer (18) comprises the external surface (12), and the metal tape (20) comprises the first inner surface (10). The first inner surface being of metal and adapted for, during local load, frictional engagement with the material of the first outer surface increases the effectiveness of a functional grip between first outer surface and first inner surface. Thus, an increased friction, in fact a frictional engagement may be achieved, when a radially inwardly directed force, e.g. from an externally provided suspension arrangement, is applied on the self-supporting cable.
Patent NZ-712373-A (NZ)
Title: Modified t lymphocytes
Inventor: ABBOT STEWART
IPC: C07K1/00
Filed: 2014-03-14
Abstract: Provided herein are T lymphocytes expressing cell death polypeptides having an extracellular domain with a CD20 epitope and a intracellular domain with an apoptosis-inducing domain of caspase 3, caspase 8, or caspase 9, wherein an apoptosis-inducing signal is generated when the polypeptide is dimerized using a CD20 antibody. Also provided herein is use of such cells, e.g., T lymphocytes, to treat diseases such as cancer.
Patent NZ-715284-A (NZ)
Title: Pyridin-2-amides useful as cb2 agonists
Inventor: ROGERS-EVANS MARK
IPC: C07D491/107
Filed: 2012-06-07
Abstract: Provided are compounds of the general formula (I) wherein the variables are as defined in the specification. Examples of the compounds include Methyl 2-(6-(3-chlorophenyl)picolinamido)-2-methylpropanoate, 6-(3-Chloro-phenyl)-pyridine-2-carboxylic acid piperidin-1-ylamide, 5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (1-methyl-1-oxazol-2-yl-ethyl)-amide and (S)-N-(3,3-Dimethyl-1-(methylamino)-1-oxobutan-2-yl)-6-phenylpicolinamide. The compounds are agonists of Cannabinoid Receptor 2 (CB2). The compounds may be useful in the treatment of pain, atherosclerosis, regulation of bone mass, inflammation, ischemia, reperfusion injury, systemic fibrosis, liver fibrosis, lung fibrosis, kidney fibrosis, chronic allograft nephropathy, congestive heart failure, myocardial infarction, systemic sclerosis, glomerulonephropathy, thermal injury, burning, hypertrophic scars, keloids, gingivitis pyrexia, liver cirrhosis or tumors.
Patent NZ-717166-A (NZ)
Title: Compositions and methods for the removal of tattoos
Inventor: FALKENHAM ALEC GUY
IPC: A61K8/55
Filed: 2014-08-28
Abstract: A method for removing a tattoo in a region of skin by administering a liposome composition comprising: soy phosphotidyl choline, sorbitan oleate and a bisphosphonate, specifically clodronate to cause fading of the tattoo in said region.
Patent NZ-725622-A (NZ)
Title: Compositions comprising aav expressing dual antibody constructs and uses thereof
Inventor: WILSON JAMES M
IPC: A61P31/12
Filed: 2015-05-13
Abstract: A recombinant adeno-associated virus (AAV) having an AAV capsid and packaged therein a heterologous nucleic acid which expresses two functional antibody constructs in a cell is described. Also described are antibodies comprising a heavy chain and a light chain from a heterologous antibody. In one embodiment, the antibodies are co-expressed from a vector containing: a first expression cassette which encodes at least a first open reading frame (ORF) for a first immunoglobulin under the control of regulatory control sequences which direct expression thereof; and a second expression cassette which comprises a second ORF, a linker, and a third ORF under the control of regulatory control sequences which direct expression thereof, wherein the second and third ORF for a second and third immunoglobulin construct. The vector co-expressing these two antibody constructs is in one embodiment an AAV, in which the 5 ‘ and 3 ‘ ITRs flank the expression cassettes and regulatory sequences.
Patent NZ-736652-A (NZ)
Title: Short synthetic peptide for treating diseases and/or conditions related to angiogenesis
Inventor: TSAO YEOU-PING
IPC: C07K7/06
Filed: 2016-04-14
Abstract: Disclosed herein are synthetic peptides and compositions comprising the same, for the treatment and/or prophylaxis of a disease or a condition related to angiogenesis. The synthetic peptide consists of 7 consecutive amino acid residues set forth as X1X2X3X4X5X6X7 (SEQ ID NO: 1), wherein, X1 is alanine (A), aspartic acid (D), asparagine (N), leucine (L), phenylalanine (F), or valine (V); X2 is alanine (A), isoleucine (I), leucine (L), or valine (V); X3 is phenylalanine (F), tyrosine (Y) or tryptophan (W); X4 is arginine (R) or lysine (K); X5 is valine (V), methionine (M), isoleucine (I), leucine (L), or glutamine (Q); X6 is arginine (R), glutamine (Q), lysine (K) or proline (P); X7 is serine (S) or threonine (T); each X2, X3, X4, X6 and X7 are independently L-form amino acid residues; and the synthetic peptide has the amino acid sequence that is any one of SEQ ID NOs: 2, 3, 4, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 and 21. When the synthetic peptide has the amino acid sequence of SEQ ID NO: 2, then at least one of X1 and X5 is a D-form amino acid residue.
Patent NZ-755806-A (NZ)
Title: Humidification of respiratory gases
Inventor: ROW NATHAN JOHN
IPC: A62B7/00
Filed: 2009-03-05
Abstract: A respiratory apparatus for providing a humidified flow of breathable gas to a patient, the respiratory apparatus comprising: a flow generator configured to supply the flow of breathable gas; a humidifier configured to humidify the flow of breathable gas, the humidifier comprising a water reservoir and a humidifier heater configured to heat water in the water reservoir; an air delivery tube with an air delivery tube heating element, the air delivery tube configured to receive the humidified flow of breathable gas from the humidifier; and a controller in communication with both the air delivery tube and the humidifier, the controller being configured to control a duty cycle of the humidifier heater and a duty cycle of the air delivery tube heating element, so that the sum of the duty cycle of the humidifier heater and the duty cycle of the air delivery tube heating element does not exceed 100%. This arrangement allows for greater power efficiency, as only one supply is needed to power one heater at a time.
Patent PT-100553-A (PT)
Inventor: THALER MARKUS
IPC: G08C19/28
Filed: 1992-05-29
Abstract: To transmit, from a transmitter to a receiver, signals triggered by prolonged depression of a button, the invention calls for repeat signals (R) to be transmitted while the button is kept depressed. Releasing the button triggers a separate switch signal (S). A burst/pause modulation technique is used to transmit the repeat and switch signals (R and S), the information units being defined by different burst-separation lengths. The burst separations and burst packets are chosen such that IR transmitters with only limited power supplies can be used.
Patent PT-106071-A (PT)
Title: Gel de quitosano e óleo essencial de thymbra capitata para o tratamento da candidose vulvovaginal
Inventor: CAVALEIRO C
IPC: A61K31/715
Filed: 2011-12-23
Abstract: A PRESENTE INVENÇÃO DIZ RESPEITO A UM GEL RESULTANTE DA ASSOCIAÇÃO DE QUITOSANO E ÓLEO ESSENCIAL DE THYMBRA CAPITATA COM VISTA À SUA UTILIZAÇÃO NO TRATAMENTO DA CANDIDOSE VULVOVAGINAL.O GEL DE QUITOSANO E ÓLEO ESSENCIAL DE TIMBRA REPRESENTA UMA ABORDAGEM INOVADORA, VISTO QUE NO MERCADO EXISTEM JÁ ALGUMAS FORMULAÇÕES FARMACÊUTICAS À BASE DE PRODUTOS NATURAIS DE APLICAÇÃO VAGINAL MAS QUE SÃO NA SUA GENERALIDADE CREMES. ESTE GEL ASSOCIA DOIS PRODUTOS NATURAIS COM COMPROVADO EFEITO ANTI-CANDIDA, O QUITOSANO E O ÓLEO ESSENCIAL, SENDO INOVADOR AO NÍVEL DA SUA FORMULAÇÃO, TECNOLOGIA E MODO DE UTILIZAÇÃO. A PRESENTE INVENÇÃO TEM APLICAÇÃO NO TRATAMENTO DA CANDIDOSE VULVOVAGINAL QUE É UMA DAS INFEÇÕES FEMININAS MAIS COMUNS, AFETANDO CERCA DE 70-75% DA POPULAÇÃO FEMININA, PELO MENOS UMA VEZ NA VIDA.
Patent RU-94016368-A (RU)
Inventor: POL AL FRED KEJN
IPC: A01N/
Filed: 1994-05-16
Abstract: FIELD: agriculture. SUBSTANCE: herbicides prepared from 2-cyano-1,3-diones have formula:: wherein R, R, R, R, Rand Rare as defined in the specification. Said compounds are intended for use against dicotyledonous and monocotyledonous weeds by pre-emergence and/or post-emergence treatment. EFFECT: improved properties of the herbicides.
Patent RU-94024103-A (RU)
Inventor: KURSAKIN G A
IPC: E21C41/22
Filed: 1994-06-27
Abstract: FIELD: mining; applicable in mining of thin and medium-thickness ore bodies. SUBSTANCE: method for mining of steeply dipping ore bodies includes formation of weak planes in mass of side rocks and filling of worked out districts with caved rocks. Pillar of side rocks is outlined with vertical weak planes and separated into blocks by lateral weak planes. These blocks are located and held in receiving working formed by intersection of vertical weak planes. Rock pillar and receiving working are imparted the form of trapezium in horizontal section, or rectangle or triangle. Passed preliminarily through rock blocks are wire ropes secured in boundary zone. Free space between rock blocks and contour of receiving working is filled with fill. Supporting-and-guarding pillar formed from rock blocks is used in the capacity of interchamber pillar in breast stoping. EFFECT: higher efficiency. 5 cl, 5 dwg
Patent RU-94025674-A (RU)
Inventor: ASTAKHIN V V
IPC: H01B3/42
Filed: 1994-07-08
Abstract: FIELD: dielectric materials. SUBSTANCE: varnish is synthesized by polycondensation of terephthalic, isophthalic acids mixture or their dialkyl esters and polyhydric alcohols in organic medium solvent followed by addition of polyorganosiloxane and tetraalkoxytitanate to the obtained resin at concentration 0.16-0.70 and 0.64-0.70 wt.-% (as measured for varnish). Before polycondensation trimellite anhydride and 4,4-diaminodiphenylmethane can be added to the mixture at their mole ratio 1:(0.5-1). Varnish is used for conductor insulation. EFFECT: improved method of synthesis.
Patent RU-94027105-A (RU)
Inventor: SKIDIN N T
IPC: C13D3/04
Filed: 1994-07-18
Abstract: FIELD: sugar industry, more particularly production of sugar. SUBSTANCE: claimed process makes it possible to intensify saturation process, increase the degree of utilization of carbon dioxide contained in saturation gas, improve purification efficiency of diffusion juice. Sugar- containing solutions are purified with air-gas mixture containing 34-60% carbon dioxide recovered from spent gases of 1 st saturation. EFFECT: more efficient purification process.
Patent RU-94030504-A (RU)
Inventor: SERGIENKO N N
IPC: C11D7/50
Filed: 1994-08-23
Abstract: FIELD: domestic chemistry. SUBSTANCE: liquid stain remover consists of chloro-containing ethylene - perchloroethylene and fusel oil at the following ratio of components, wt.-%: perchloroethylene 60-70, and fusel oil 30-40. Proposed composition can remove fat-oil pollutions and pollutions based on synthetic enamels and lacquers. EFFECT: enhanced effectiveness of composition.
Patent RU-94036805-A (RU)
Inventor: MUZYKA V I
IPC: A23K1/16
Filed: 1994-09-30
Abstract: FIELD: food production. SUBSTANCE: food addition for poultry and mammalian has polysaccharide fractions obtained from Ungernia callus tissue or their mixtures with cultural fluid, vitamins and trace elements. Food addition is harmless. EFFECT: increased daily weight, decreased epizootic disease of young animals. 2 tbl
Patent RU-94039003-A (RU)
Inventor: KOSNIKOV JU N
IPC: G09G1/16
Filed: 1994-10-04
Abstract: FIELD: TV devices. SUBSTANCE: second memory unit stores codes of coefficients which are processed by interpolator for generation of smoothly varied pedestal signal which is added by adder with discrete signal for illumination of small details (this signal is received from first memory unit through code-to-voltage converter). In addition memory units contain codes of addresses for finish of illumination of small details and codes of addresses for finish of interpolation of pedestal signal. These codes are sent to comparison units which also receive from counter a code of current position of electronic beam on line. counters address memory unit in alternating order so that shift from one part of line to another part is achieved. This is done by sending of signals from comparison units to counters. Thus comparison units detect time when processing was finished. Synchronization unit provides synchronization of counters and image sweeping on screen. Generator of video signal mixes signal of illumination of raster line with synchronization signal and generates full video signal for TV. EFFECT: increased quality of output image due to possibility of smooth alternation of brightness on arbitrary part of raster line.
Patent RU-94040099-A (RU)
Inventor: BOLDIN V A
IPC: E21F5/00
Filed: 1994-10-27
Abstract: FIELD: mining; applicable in mining of coal fire-hazardous seams for detection of fires in hard-to-reach mine worked-out space. SUBSTANCE: method for location of spontaneous mine fire seat includes drilling of control holes into worked-out space of the troubled district from the surface and holes are to be cased with metal pipes. Distance between holes to seam dip and strike shall be within 40-60 m. Relative humidity of air coming through holes from worked out space is measured by psychrometer. Obtained values of relative humidity are compared with relative humidity of mine air of worked out space of same seam of the district where there is no fire. Boundaries of spontaneous fire seat are determined by reduced relative humidity of the air coming from holes; and the center of fire seat is located by minimum value of relative humidity. EFFECT: higher efficiency. 2 dwg, 1 tbl
Patent RU-94043394-A (RU)
Inventor: ZHAGIN B P
IPC: E21B43/28
Filed: 1994-12-08
Abstract: FIELD: mining. SUBSTANCE: method involves underground leaching gold and silver from sulfide, carbonate and other ores in their occurrence with use of weak solutions (0.2-0.7 %) of chlorine and sodium thiosulfate. At the first stage of leaching chlorine is supplied so that pH of pumped out solution is maintained above 3.0. Active chlorine prior to processing gold-containing solution is reduced by ammonia, manganese salts or by some other reducing agents. At the second stage silver is leached with thiosulfate (0.2-0.7 %). Productive solutions are processed by cementation, sorption or electrolysis. Solution remaining in the bed has pH equalling that of initial bed waters and chloride-sulfate mineralization within 3 g/l. Recovery of gold and silver exceeds 80%. EFFECT: higher efficiency.
Patent RU-94044423-A (RU)
Title: Russian chess
Inventor: IGNATCHENKO I F
IPC: A63F3/02
Filed: 1994-12-15
Abstract: FIELD: playing devices. SUBSTANCE: chess has chess-board 1 with alternating fields of two colors: black fields 2 and white fields 3 defined by groups of intersecting parallel lines, and identical sets of figures of different colors. Fields are made triangular and are defined by three groups of intersecting parallel lines extending from bottom to the top and to the left (4), from bottom upward and to the left (5) and horizontal lines 6. Chess-board 1 is made in the form of regular hexagon with side equal to six sides of triangular field. Number of figure sets is from two to six. Each set has one king figure 7, one queen figure 8, two castle figures 9, two bishop figures 10, two knight figures 11 and nine pawn figures 12. Sets may have seven or fourteen pawn figures 12. Each set has auxiliary figure (ring) 13. Six central fields are defined by common line 18 (thickened or of other color), forming central hexagon 19. EFFECT: increased entertainment effect, wider playing abilities and increased number of players. 7 cl, 10 dwg