baber/WOPTO huggingface dataset:
Patent CR-20230258-A (CR)
Title: Small molecule compounds and compositions
Inventor: WIDDOWSON KATHERINE
IPC: C07D211/34
Filed: 2021-11-19
Abstract: gene with a mutant promoter. Further provided are small molecule compounds or compositions having beneficial effects in cancer treatment. Methods of making the compounds and compositions and methods of using the compounds and compositions, such as using the compounds and compositions to treat cancer, are also provided.
Patent EC-SP034872-A (EC)
Title: Nuevos heterociclos 3
Inventor: BISCHOFF HILMAR
IPC: A61P29/00
Filed: 2003-12-01
Abstract: La invención se refiere a 7-(4-terc butil-ciclohexil)-imidazotriacinonas, a procedimientos para su preparación y a su uso en medicamentos, especialmente para el tratamiento y/o profilaxis de procesos inflamatorios y/o enfermedades inmunitarias.
Patent EC-SP951385-A (EC)
Title: Composiciones farmaceuticas paracetamol con metionina
Inventor: SPENCER JONES ROGER
IPC: A61K9/00
Filed: 1995-02-17
Abstract: Un proceso mejorado para la producción de una composición farmacéutica comprendiendo la p-hidroxiacetanilida y la l-cisteina o un compuesto que es convertido a eso en vivo una mezcla conteniendo la p-hidroxiacetanilida y la l-cisteina o su precursor en estado sólido y luego formando la mezcla sólida.
Patent EC-SP982400-A (EC)
Title: Compuestos farmacologicos de descarbietoxiloratadina sin lactosa, no higroscopicos y anhidros
Inventor: REDMON MARTIN P
IPC: C07D295/02
Filed: 1998-01-06
Abstract: Presentación al público de compuestos farmacológicos estables de descarboetoxiloratadina (DCL), un derivado metabólico de la loratadina, para el tratamiento de la rinitis alérgica y otras afecciones provocadas por histaminas. Los compuestos se formulan de manera que evitan las incompatibilidades entre la DCL y los excipientes reactivos, como la lactosa y otros mono o disacáridos. Los compuestos presentados incluyen compuestos de DCL farmacológicamente estables, sin lactosa, no higroscópicos y anhidros.
Patent FI-20051072-A (FI)
Inventor: UHLMANN EUGEN
IPC: C12Q1/68
Filed: 2005-10-24
Abstract: Polyamide-oligonucleotide derivatives (I) and their physiologically acceptable salts. Polyamide-oligonucleotide derivatives of formula F((DNA)-Li)q(PNA-Li)r(DNA-Li)s(PNA)t)xF' (I) and their physiologically acceptable salts are new. q, r, s, t = 0 or 1, with the sum of two or more adjacent letters at least 2; x = 1-20; DNA = nucleic acid (such as DNA or RNA or their known derivatives); Li = covalent linkage between DNA and PNA, i.e. a bond or a residue containing at least one atom of carbon, nitrogen, oxygen or sulfur; PNA = polyamide structure containing at least one nucleobase different from thymine; and F, F' = end groups and/or are connected through a covalent bond. Independent claims are also included for the following: (1) method for preparing (I); (2) pharmaceutical composition containing (I); and (3) gene probe assays for detecting oligo- or poly-nucleotide targets (RNA or DNA) in which (I) is used as probe and primer.
Patent FI-20060625-A (FI)
Inventor: AASTRAND ERIK
IPC: D04H1/4209
Filed: 2006-06-28
Abstract: The invention relates to a method for the manufacture of an integrated mineral fiber product. In the method a first and a second primary mineral fiber web, which both are of a certain width, are obtained. The first and the second primary mineral fiber web are placed at least partly on top of each other, so that a combined primary web is obtained, which shows a first and second edge part and a middle part between them, and the combined primary web is transported in a first direction. A secondary mineral fiber web is obtained by overlapping the combined primary web transversely in regard to the first direction, whereby the combined primary web is arranged to partly overlap itself so that the perpendicular distance between two successive foldings of the combined web defines the width of the secondary fiber web, and the edge parts of the combined web make up at least a part of the large surfaces of the secondary web. The obtained secondary fiber web is hardened in a hardening furnace, and cut into final products of a suitable size. The first and second primary fiber webs are selected or manufactured so that in the first primary fiber web at least one of the following properties: mean fiber diameter, mean fiber length, surface weight, fiber amount, chemical composition, binder concentration or binder composition, differs at least 5 % from the corresponding value in the second primary fiber web. The invention also relates to a mineral fiber product.
Patent FR-1601166-A (FR)
Title: Clothing mattress carcass with foam
IPC: A47C27/05
Filed: 1968-12-30
Granted: 1970-08-10
Abstract: Mattress carcass has an envelope. A plastics foam is expanded on the envelope; pref. this is partly of prefabricated plastics, connected by the foam. The prefabricated pieces are foam plates, partially covering the carcass before the foam is expanded. Pref. an open-cell foam is used.
Patent GB-1051545-A (GB)
IPC: B23B11/00
Abstract: 1,051,545. Screw cutting lathe. MANUFACTURE DE MACHINES DU HAUT-RHIN S.A. July 10, 1964 [July 12, 1963], No. 28679/64. Heading B3T. A screw cutting lathe comprises a work spindle 1, a shaft 14 having a cam drum 29 fixed thereon, a tool slide 36 slidable on a transverse slide 42 slidably carried on a second transverse slide 44 which is transversely movable on a base 45. A shaft 10 is driven from spindle 1 through a gear train 2-9, and a sleeve 13 is driven through gears 11, 12. Shaft 14 is driven through a dog clutch 15 urged into engagement by a spring 16, and prevented from thus engaging when required, by a pivoted lever 17. The latter is actuated by a second lever 24 controlled by a cam drum 21 mounted on a shaft 28, which also carries a second cam 43. Cam drum 29 has a track 30 which controls the movement of rods 39, 40, so that a cam 41 is pivoted to advance or retract slide 42. A second track 31, controls the reciprocating movement of a carriage 32. The upper part of this carriage has an adjustable guide 33, so that the reciprocating movement is transmitted to slide 36, through rods 35, 37. Cam 43 positions slide 44 relative to base 45 through a lever 46, having a micrometer adjustment 47.
Patent GB-1052182-A (GB)
IPC: B29C67/00
Abstract: 1,052,182. Beaded-edge films. FARBENFABRIKEN BAYER A.G. Aug. 27, 1963 [Aug. 28, 1962], No. 33888/63. Heading B5B. Films of thermoplastic synthetic material produced by a solution casting or melt casting method and having smooth edges are subsequently provided with edge beads by a process comprising continuously extruding strands of molten material and rolling them in the hot state on to the outer edge of the margins of the travelling film. Preferably the melt strands are so applied to the outer margins of the film from the side that they completely enclose the edges of the film. Apparatus as shown comprises two oppositely rotating rollers 2, 3 arranged one above the other in a frame and between which the film 1 is conveyed, the ends of the rollers being formed with profiled grooves 4 and closed off laterally by fixed plates 6 defining the grooves, extruder nozzles 7, 8 being arranged on both sides of the rollers, the openings of the nozzles facing the grooves of the rollers. Strands of melt continuously discharging from the nozzles 7,8 fill the grooves of the rollers, so that the edges of the film are embedded in the strands of melt and thus beads 11 and 12 are formed on both sides of the smooth edges 9 and 10 of the film, these beads fusing with the said edges and being given a uniform smooth form by the rolling operation. The material for the strands may be that of the film or a thermoplastic material different from that of the film.
Patent GB-1053194-A (GB)
IPC: B41B11/54
Abstract: 1,053,194. Type - bar - making machines. LINOTYPE G.m.b.H. June 17, 1965 [June 18, 1964], No. 25646/65. Heading B6W. Driving-mechanism; moulds; magazines.- When the magazine shift mechanism 1 moves into operative position a magazine 2 containing matrices for casting large types, a cam 3 closes a micro-switch 4. When a mould, in a mould wheel 40, for casting large types, is in casting position, a cam 8 closes a micro-switch 5. When switches 4, 5 are both closed, a solenoid 7 is energized and disengages a friction clutch 14, 15 so that the drive from a belt pulley 16 to a cam-shaft 31, carrying a plurality of cams for controlling the movements of the various components of the casting-machine, is interrupted for a period defined by a pre-settable delay mechanism 6. The time elapsing between casting and ejection of a line of large type is thus extended to allow satisfactory cooling of the metal.
Patent GB-1053307-A (GB)
IPC: C07D413/04
Abstract: 1,053,307. 1-Hydroxy-1,2-dihydro-1,3,5-triazines. UPJOHN CO. Feb. 26, 1964 [April 16. 1963], No. 8020/64. Heading C2C. The invention comprises compounds of the Formula I and their acid addition salts, wherein R 1  represents a hydrogen atom or a C 1-4  alkyl group, R 2  represents a hydrogen atom or a C 1-4  alkyl or piperidino group and R 3  represents a C 2-8  dialkylamino, dibenzylamino or bis-(2- hydroxypropyl) amino group or an N-aziridinyl, N-azetidinyl, N-pyrrolidinyl, piperidino, N- hexahydroazepinyl, heptamethyleneimino, oc. tamethyleneimino or morpholino group, each of the above heterocyclic radicals having optionally attached thereto 1 to 3 C 1-8  alkyl radicals, and compounds of the Formula IV wherein R 8  represents a C 2-8  alkenyl radical, R 9  represents a C 1-8  alkyl radical or a C 2-8  alkenyl radical and R 6  and R 7  represent C 1-4  alkyl or C 2-4  alkenyl radicals. Compounds of the Formulae I and IV are prepared by mixing triazines of the Formulae II and V respectively with a compound of the Formula III wherein X represents a halogen atom or a C 1-8  alkyl, C 1-8  alkoxy, or nitro group and n represents 0 to 5. Compounds of the Formula I wherein R 3  represents a C 2-16  dialkylamino group are prepared by hydrogenating compounds of the Formula IV in the presence of a hydrogenation catalyst. Compounds of the Formula I wherein R 1  and R 2  represent hydrogen atoms are prepared by reacting a cyanoguanidine of the Formula R 3 -C(: NH)NHCN with cyanogen bromide in the presence of a strong base and reacting the resulting dicyanoguanidine salt with a hydroxylamine acid addition salt. Triazines of the Formulae II and V may be prepared from cyanuric chloride by appropriate replacement of the three chlorine atoms by primary, secondary and tertiary amino groups. Therapeutic compositions with anti-hypertensive, vasodilatory, antisecretory and central nervous system depressant properties in the forms of tablets, capsules, powders, pills, granules, syrups, elixirs, suppositories, solutions, and dispersions, for oral, topical and parenteral application, comprise compounds of the Formula I and acid addition salts thereof together with a pharmaceutically acceptable carrier.
Patent GB-1083985-A (GB)
Abstract: 1,083,985. Sliding doors. MATHER & PLAIT Ltd. Feb. 1, 1966 [Feb. 11, 1965], No. 5926/65. Heading E1J. A folding leaf door arrangement (Fig. I) has bottom guide lugs 3 running in a channel 4 to pass an impediment, e.g. a rail 2, and slide upward against a restoring force, e.g. a spring 12 or a block of rubber, the lower end of each lug 3 lifting on contacting the impediment. The lower end of each guide lug 3 may have a roller serving to lift the lug. Two or more secondary guide lugs, eg 17, 18, (Fig; 5) may be provided on the leading post of the door. There may be at least two secondary guide lugs 17, 18, mounted on the leading post of the door, to engage in and run along a secondary channel 22, parallel to the channel 4 and having flared ends.
Patent GB-1115832-A (GB)
Abstract: 1,115,832. Gyroscope gimbals. LITTON INDUSTRIES Inc. Nov. 23,1965 [Dec. 11, 1964]. No. 49762/65. Headings G1C and G1F. Gimbal rings for use in supporting a gyroscope or an inertial platform are constructed of four separate segments held together by screws and located with respect to each other by locating pins or recesses. Two of the segments, opposite each other, may carry bearing assemblies incorporating electric pick-off on torquer coils, and two or more of the segmented gimbals may be rested inside one another. The gimbal segments are preferably of aluminium, magnesium, or beryllium, and the bearing assembly housings of titanium, or non- magnetic stainless steel, on elastomeric plastics or rubber film being interposed between the housing and the gimbal segment to allow for differences in thermal expansion. The bearings may have a central aperture to allow the passage of flat tape electrical leads held in place by slots in end covers for the bearing.
Patent GB-1226247-A (GB)
IPC: C07D213/71
Filed: 1969-03-25
Abstract: 1,226,247. Pyridine derivatives. ZAIDAN HOJIN DOHMYAKUKOHKA KENKYU SHOREIKAI. 25 March, 1969 [8 April, 1968 (2); 14 Sept., 1968], No. 15525/69. Heading C2C. Novel, therapeutic compounds I wherein R 1  is H or alkyl, R 2  is H, alkyl, allyl, aryl, aralkyl, furfuryl, picolyl or pyridyl, R 3  is H or alkyl, and R 4  signifies H, alkyl, CO 2 R 5  (R 5  is alkyl) or CONR 6 R 7  (R 6  and R 7  signify H or alkyl) and R 1  and R 2  and R 3  and R 4  can together form a divalent alkylene chain which may be interrupted by a heteroatom, are obtained: (a) by the interaction of a compound II with an isocyanate, R 2 NCO (R 2  may not be H); (b) by converting a compound II into an ester III utilizing standard methods and thereafter reacting the ester with a base, NHR 1 R 2  (Ar signifies an aryl group, e.g. pH; or (c) by converting a compound II into the corresponding chlorocarbonic ester utilizing phosgene and subsequently treating the ester with a base, NHR 1 R 2 .
Patent GB-1227090-A (GB)
IPC: H01F10/06
Filed: 1969-07-24
Abstract: 1,227,090. Magnetic storage devices. THOMSON-CSF. 24 July, 1969 [25 July, 1968], No. 37350/69. Heading H3B. In a method of making a magnetic storage device, Fig. 4, successive layers of copper 12, permalloy 1, and copper 13 are deposited on a layer of varnish on a glass substrate 10, the permalloy being electrodeposited as a toroidal element centred on a hole formed by photoengraving after vacuum deposition of layer 12. The substrate is removed by dissolving the varnish, and a gold conductor 2, Fig. 7, is formed electrolytically to pass through the hole, and then parts of the initial copper layers of Fig. 4 are etched down to the torroid so that the torroid may be secured to the gold conductor by insulating material 15. The remaining copper is then dissolved and replaced by an insulating layer 17 which enters the structure by capillary action. More than one gold conductor may pass through the hole, and devices of different speeds may be made according to the thickness of magnetic material used.
Patent GB-1234454-A (GB)
IPC: F04D13/02
Filed: 1968-06-20
Abstract: 1,234,454. Stirrers; driving. BETEILIGUNGS-AG FUR HAUSTECHNIK. 20 June, 1968 [22 June, 1967], No. 29515/68. Heading B1C. [Also in Divisions B3, E2 and F2] A mixing-vessel 20 comprises a magnetic armature 25 which carries a blade-ring 26, and is mounted by means of a ball and socket joint 9, 12 (see Division F2). The torque is provided by a motor 27, which drives a disc 28 on the inside of which a concave annular laterally magnetised permanent magnet is located.
Patent GB-1238932-A (GB)
IPC: C07F7/12
Filed: 1968-06-14
Abstract: 1,238,932. Fluorinating organosilicon compounds. INSTITUT FUR SILIKONUND FLUORKARBON-CHEMIE. 14 June, 1968, No. 28424/68. Heading C3S. Organosilicon compounds are fluorinated by reacting with the fluoride of Li, Na, Mg, Ca, Sr, Ba or Al in the presence of hydrogen chloride and an alcohol or of an aqueous solution of an acid stronger than hydrofluoric acid. The HC1 or other acid may be prepared in situ by reaction of the silane with water or alcohol. Suitable acids are aqueous hydrochloric, sulphuric or nitric. Silicon compounds which may be used include chlorosilanes, alkoxy silanes, silazanes, acetoxy silanes, silanols, siloxanes and aminosilanes. Specification 1,238,931 is referred to.
Patent GB-1239526-A (GB)
IPC: H01M6/34
Filed: 1969-07-23
Abstract: 1,239,526. Inert batteries. MAGNAVOX CO. 23 July, 1969, No. 36959/69. Heading H1B. An inert battery activatable by immersion in an electrolyte, with the plates of the cells supported by header plates at opposite ends of the cell plates has a filling/venting channel formed in each header plate which intersects the cell plates obliquely. As shown in Fig. 5a the channel 50b in header plate 28 intersects the cell plates at an oblique angle which increases the electrolyte path between cells and also contains baffles 52 which further increase the path. The baffles may be omitted or replaced by barriers which leave a narrower channel in the middle (Fig. 5b, not shown). The batteries described are Agbl/sea water/Mg or Zn batteries.
Patent GB-1257024-A (GB)
IPC: B01D53/02
Filed: 1968-02-06
Abstract: 1,257,024. Separating aromatic hydrocarbon mixtures. BRITISH PETROLEUM CO. Ltd. 4 Feb., 1969 [6 Feb., 1968], No. 5795/68. Addition to 1,104,314. Heading C5E. One or more components of a hydrocarbon mixture comprising C 8  and/or C 9 , alkyl and/or alkenyl, aromatic hydrocarbons are separated by contact in the vapour phase with a PNT-type compound having the basic nuclear structure and which forms an inclusion complex more readily with one or more components of the mixture than with the other components, followed by partial desorption in the vapour phase of the more readily absorbed component(s) by partial pressure stripping or inert gas elution, the desorption being so conducted that the PNT-type compound is maintained as an inclusion complex and contains at all times a minimum of 70% of its maximum uptake of included material. The process is continuous and comprises repeated absorption and desorption cycles as above. Suitable PNT compounds are tris-(o-phenylenedioxy) cyclotriphosphazene, tris - (o - phenylenediamino) cyclotriphosphazene and tris-(2,3-naphthyldioxy) cyclotriphosphazene. Such compounds may be used in the free state, or admixed with a thermosetting resin binder, or on an inert support.
Patent GB-1259451-A (GB)
IPC: H04M19/04
Filed: 1967-11-29
Abstract: 1,259,451. Substation equipment. GENERAL ELECTRIC CO. Ltd. 27 Feb., 1969 [29 Nov., 1967], No. 54325/67. Headings H4J and H4K. [Also in Division G5] A tone sounder for use in a subscriber's set in place of the bell, comprises a carbon microphone 2 whose diaphragm 10 is mechanically linked 9 to the armature 8 of a rocking armature receiver 1 so that when a ringing signal is applied over the line wires 6, 7, a sustained oscillation is set up whereby an audible calling tone is produced. The sounder may be cut out of circuit when the handset is lifted. The diaphragm 10 may be loaded so as to adjust the frequency of the tone. A thermistor 4 is provided to prevent speech signals being transmitted to line via the sounder when the handset is on hook.
Patent GB-1259482-A (GB)
IPC: B22D41/50
Filed: 1969-02-14
Abstract: 1,259,482. Ladles. SCHLOEMANN A.G. 5 Aug., 1969 [14 Feb., 1969], No. 8035/69. Heading F4B. A pouring spout 2 is connected to the outlet duct 1a of a ladle bowl 1 by means of a trough 2b, enclosing the end block 3 of the said spout, extending into a trough 1c formed adjacent an outlet 1b in the shell 10 of the ladle bowl, a cylindrical tube 4 being arranged within the trough 1c to connect the outlet duct 1a to the spout, such that on connection said tube 4 and part of the end block 3 can be surrounded by tempering material. Above the trough 1c is disposed a cover 7 secured by wedges 8 and bolts 6. Flanges 1d and 2a are used to couple the troughs 1c and 2b together.
Patent GB-1266212-A (GB)
IPC: C03B37/083
Filed: 1969-10-24
Abstract: 1,266,212. Glass fibre manufacture. PPG INDUSTRIES Inc. 24 Oct., 1969 [28 Oct., 1968], No. 52169/69. Headings C1M. A bushing unit for producing glass fibres comprises a bushing 10, a frame 12 in spaced relation to the bushing, and a mass of refractory material 14 between the bushing and frame, the frame being constructed of cast iron. The type of cast iron preferably used is ferritic nodular cast iron, although white or grey cast iron may be used. The bushing frame is provided with portions to receive cooling tubes 18 and thermocouple wires 20 and has lugs (16) for attachment to a forehearth. The bushing 10 is provided with a plurality of tips 22 having orifices 24 and in use is heated by an electric current received through bus-bars 26. Reference has been directed by the Comptroller to Specification 923,602.
Patent GB-1266945-A (GB)
IPC: B21J15/36
Filed: 1969-09-26
Abstract: 1,266,945. Riveting. HUCK MFG. CO. 26 Sept., 1969 [30 Sept., 1968], No. 47606/69. Heading B3U. A tool for setting a pin and collar type fastener includes a piston 50 comprising a forward rod portion 54 operatively connected to pin gripping jaws 68 and a rearward rod portion 56, both rod portions 54, 56 being connected to a head portion 52 and mounted for reciprocation in bores 42, 36 which have their axes X eccentric to the axis Y of the main bore 14 in which the head portion 52 reciprocates. The piston 50 is moved rearwardly by fluid under pressure introduced through a passage 90 in an adapter 38, passage 92 in a cylinder head 28, a tube 96 and port 100. The jaws 68 are thereby moved inwardly to grip the pin and apply an axial force thereto whilst the collar is swaged by an anvil 22. The jaws 68 are urged into the closed position by a follower 82 urged against the jaws 68 by 0-rings 84. After setting, the piston 50 is moved back by applying fluid pressure through passages 102, 104. The jaws 68 are engaged by an annular shoulder 76 of a release member 72 to cause them to open to release the pin. A collar ejector 74 is moved by the rod portion 54 to cause the swaged collar to be ejected from the anvil 22.
Patent GB-1288267-A (GB)
IPC: G21C3/06
Filed: 1969-06-04
Abstract: 1288267 Fuel elements UNITED KING- DOM ATOMIC ENERGY AUTHORITY 29 May 1970 [4 June 1969] 28349/69 Heading G6C The zirconium/tin alloy container for a nuclear fuel element is treated by heating in the α-phase to anneal and partially remove cold work. Treatment at 650 C. for one hour is preferred. In a zirconium/tin alloy treated in this manner, the yield stress is lowered below the threshold stress for crack propagation and the material yields in a ductile manner. The treatment is most effective with containers produced by tube reduction but there is also some improvement with cold drawn containers. There should be no further working after the heat treatment. In a closed end burst test conducted at 300 C., a container previously heated at 650 C. for one hour had a circumferential elongation of 50%.
Patent GB-1288900-A (GB)
IPC: B25C1/18
Filed: 1971-04-19
Abstract: 1288900 Explosively-actuated fastener-driving tools OLIN CORP 19 April 1971 [12 June 1970] 45633/71 Divided out of 1288897 Heading B4C The apparatus forming the subject-matter of the invention is the same as is described in the Specification 1,288,897 but the claims relate to the power adjustment arrangement (viz. a power adjustment drum).
Patent GB-1290069-A (GB)
IPC: B02C17/24
Filed: 1970-12-31
Abstract: 1290069 Tube mills WEDAG WESTFALIA DINNENDAHL GROPPEL AG 31 Dec 1970 [20 Jan 1970] 61984/70 Heading B2A [Also in Division H2] A Tube mill or rotary drum 1 is mounted at its ends in rolling contact bearings 2. The ends of the drum have closure covers 3, provided with apertures for an inlet 4 and outlet 5. The drum is driven by a motor 6 whose rotor 7 is fastened on the drum, the stator 8 being supported on the foundations. The bearing mounting permits the use of a small air gap 9 between rotor and stator.