baber/WOPTO huggingface dataset:
Patent AT-E150008-T1 (AT)
Inventor: HAYASHI KYOZO
IPC: C07C235/38
Filed: 1992-05-14
Granted: 1997-03-15
Abstract: Aromatic amide compounds of the formula: <CHEM> wherein R1, R2, and R3 are independently hydrogen, a lower alkyl or lower alkoxy group; Ar is an optionally substituted aromatic group; the group <CHEM> is C=C or HC-CH; X is hydrogen, CH2COOH or CH2CONHAr; and Y is hydrogen or COOH; provided that when X is CH2COOH or Y is COOH, the COOH may be taken together with the adjacent hydroxy group on the benzene ring to form a lactone ring by dehydration, a quinone form thereof or a pharmaceutically acceptable salt thereof have potent nerve growth factor (NGF) secretion inducing activity, and are thus useful as a drug for the treatment or prophylaxis of degenerative nervous system disorders such as senilic dementis, and Alzheimer's disease.
Patent AT-E143626-T1 (AT)
Inventor: GELLERT JOBST ULRICH
IPC: B23P15/00
Filed: 1992-12-10
Granted: 1996-10-15
Abstract: A method of manufacturing a metallurgically monolithic integral heated probe for injection molding. An electrical terminal (80) and three portions (90,92,60) of the probe body are made and assembled together with an electrical heating element (72) extending in an aligned bore. The forward portion (90) is made of abrasion resistant high speed steel, while the rest of the probe body is made of hot work tool steel. A removable and reusable filler tube (132) is screwed into a threaded seat (88) in the rear cap portion (60) and a quantity of silver (136) is loaded into it. After a nickel alloy brazing material (131) is applied to the joins, the assembly is heated in a reduced oxygen atmosphere in a vacuum furnace according to a predetermined cycle. The nickel alloy seals all the joins and the silver braze fills all the spaces between the components to provide a metallurgically monolithic integral probe. Using silver which is more conductive and has a lower melting temperature than copper reduces the cycle time and avoids having to heat the assembly into the austenitizing range of the steel body. <IMAGE>
Patent AT-E147972-T1 (AT)
Inventor: LOWE LIONEL BARRY
IPC: A23K1/18
Filed: 1992-04-03
Granted: 1997-02-15
Abstract: A sustained release capsule adapted to be inserted into the rumen of a ruminant animal and means for retention of the capsule in the rumen. <??>A sustained release capsule (8) adapted to be inserted into the rumen of a ruminant animal through its oesophagus and retained within the rumen over a prolonged period to continuously deliver a biologically active composition (32) carried in the capsule (8), comprising an elongated tubular body (10) comprising a tube (16) and an end cap (12) secured to one end thereof for substantially enclosing the biologically active composition (32), the other end of the capsule (8) being a delivery end (18), the body (10) having an opening (20) at the delivery end (18) of the capsule (8) for delivery of the composition (32) to the rumen, and a plurality of retention arms (44) attached to or formed integrally with the cap (12), the arms (44) being adapted to extend outwardly from the cap (12) for retaining the capsule (8) in the rumen, the arms (44) being resilient to enable them to bend from their outwardly extending positions toward the body (10) so that they lie alongside the body (10) allowing the capsule (8) to be inserted through the animal's oesophagus, the resilient arms (44) normally extending from the body (10) at an angle between 75 DEG  and 90 DEG  with respect to the axis of the tubular body (10), and for each arm (44) said cap (12) has an external curved surface (26) disposed with respect to the arm (44) so that when the arm (44) is bent toward the body (10), the arm (44) contacts the curved surface (26) and the curved surface (26) controls the bending of the arm (44) so that the arm (44) does not bend abruptly, said arms (44) being adapted to return to their outwardly extending positions when the capsule (8) reaches the rumen, characterised in that said cap (12) is secured to said one end by means of at least two circumferential beads (30) having at least one sealing ring (31) located therebetween. <IMAGE>
Patent AT-E161586-T1 (AT)
Inventor: WESTERN LINDA M
IPC: C12N15/09
Filed: 1992-10-09
Granted: 1998-01-15
Abstract: A method is disclosed for extending an extender probe to produce a single stranded polydeoxynucleotide that is free of unreacted extender probe and has two segments that are non-contiguous and complementary with each other. The method comprises the steps of (1) providing in combination (a) a polynucleotide having two non-contiguous, non-complementary nucleotide sequences S1 and S2 wherein S2 is 5' of S1 and is at least ten deoxynucleotides long, (b) an extender probe comprised of two deoxynucleotide sequences, wherein the sequence at the 3'-end of the extender probe (EP1) is hybridizable with S1 and the other of the deoxynucleotide sequences (EP2) is substantially identical to S2 and (c) means for modifying the 3'-end of extender probe that does not hybridize with the polynucleotide and (2) extending the extender probe along the polynucleotide wherein extender probe not hybridized to the polynucleotide becomes modified at its 3'-end. A method is also disclosed for forming a polynucleotide sequence complementary to a single stranded target polynucleotide sequence ("target sequence"). In the method a polynucleotide primer having a 3'-terminus comprised of a nucleotide monophosphate, which has at least one phosphate-sulfur bond, is hybridized to the 3'-end of the target sequence. The polynucleotide primer is extended along the target sequence and the extended polynucleotide primer is then dissociated from the target sequence. The method finds particular application in the area of nucleic acid amplification.
Patent AT-E127759-T1 (AT)
Inventor: TABUENCA GARCIA ANA
IPC: B44D7/00
Filed: 1992-06-11
Granted: 1995-09-15
Abstract: It consists in fastening the painting (2) or article in question inside a frame (1) with the collaboration of belts (4) which are tensioned appropriately between buckles (5) so that each belt (4) has the configuration of a flat ring inside which the painting (2) is accommodated, the painting remaining fastened with the collaboration of half-clamps (6) mounted on the belts (4) and fastened by means of the clamps (9). In this manner, the painting (2) or article in question is mounted in a "floating" manner inside the frame (1) which, in turn, is mounted in a floating manner in the transport vehicle by means of vibration-insulating supports (3). <IMAGE>
Patent AT-E129626-T1 (AT)
Inventor: HIEMISCH CHRISTIAN
IPC: A61F2/60
Filed: 1993-03-12
Granted: 1995-11-15
Abstract: The invention relates to a connecting element of a ball-and-socket joint (2, 6) between elements (1, 4) of a leg prosthesis with a flange intended for fastening on one component (1) on which there is arranged an adjusting element (2, 3) comprising a spherical cap (2) and a quadrangular pyramid (3) centrically placed on its vertex thereon. In order to improve the connecting part in terms of its possible adjustment it is proposed that the flange be a square four-holed flange (8) on which the adjusting element (2, 3) is eccentrically arranged. <IMAGE>
Patent AT-E187065-T1 (AT)
Inventor: KWON KIM H
IPC: A61P17/00
Filed: 1993-03-26
Granted: 1999-12-15
Abstract: Novel compositions comprising an antiandrogenic compound of the formula <CHEM> wherein R is COR1 wherein R1 is loweralkyl and a vehicle comprising a metabolism modulator and a polar organic solvent, are disclosed.
Patent AT-E178311-T1 (AT)
Inventor: LATTER VICTORIA
IPC: A61K31/122
Filed: 1989-08-15
Granted: 1999-04-15
Abstract: The present invention relates to the use of known and novel naphthoquinones in the treatment and prophylaxis of Pneumocystis carinii infections, and for the manufacture of medicaments for the treatment and prophylaxis of P.carinii infections, novel formulations containing said compounds, and novel naphthoquinones of formula (VI):   <CHEM>  wherein R<1><1> and R<1><2> each represent =O and the dotted line represents a double bond between the 2 and 3 positions of the quinone ring, in which case R<1><3> represents a group - OCOR5; a group OR<6> or SR<6>; or a group NR<7>R<8>; or the dotted line represents double bonds at the 1,2 and 3,4 positions of the quinol ring and R<1><1>, R<1><2> and R<1><3> each represents a group -OCOR<1><4>, wherein R<1><4> represents an optionally substituted C1-10alkyl group.
Patent AT-E180029-T1 (AT)
Inventor: ZANONI EDOARDO
IPC: E04B2/74
Filed: 1993-11-25
Granted: 1999-05-15
Abstract: A set of metal sections has been invented for the construction of movable partition walls (80;88;102) that are practically smooth externally with no irregularities; there is a first metal section (1;10;12;17) constituting uprights for supporting panels (81;103) of said partition walls (80;88;102), that comprises a tubular casing (2;13) provided with joining means (3,4;14,15) suitable for engaging with connecting means (18,84,86;90,91,92;21;34;40) fastened to substantially internal surfaces of said panels (81,103), so that in the finished movable partition walls (80;88;102), said uprights (1;10;12;17) remain inside the layer formed by said panels (81,103). <IMAGE>
Patent AT-E159488-T1 (AT)
Inventor: LA VANGE DONALD H
IPC: B65D47/26
Filed: 1992-12-29
Granted: 1997-11-15
Abstract: A child resistant dispensing closure having a cap and a spout mounted thereon for rotation about a substantially horizontal axis. The upper surface of the spout is provided with a plurality of ribs, each of which has a distinct energy plane. Only one rib, usually, the rearmost, allows sufficient purchase to produce the force vector necessary to initiate rotation of the spout when a manual force is applied thereto. The cap includes a cylindrical skirt with a frusto-conical section extending upwardly therefrom. A protective flange extends upwardly about the perimeter of the upper end of the frusto-conical section to deter unauthorized access to the spout. The upper wall of said cap is canted at an acute angle to a horizontal plane passing through the cylindrical skirt of the cap, so that the spout is further recessed within the protective flange.
Patent AT-E139124-T1 (AT)
Inventor: DUROSELLE PATRICK
IPC: A61G12/00
Filed: 1993-09-21
Granted: 1996-06-15
Abstract: The invention relates to a device for the decontamination of waste materials of the type comprising a decontamination housing (5), an ozone generator (1) capable of supplying said housing (5) with ozone-containing gas, an ozone destructor (16) capable of destroying the ozone of the ozone-containing gas held in the decontamination housing (5). The device of the invention also comprises an ozone gas accumulator (4) arranged between the ozone generator (1) and the decontamination housing (5), said accumulator (4) being capable of establishing with the ozone generator (1), through appropriate conduits (22, 23, 24), a closed circuit so as to increase and rapidly modify the ozone concentration in the gas intended to circulate in the decontamination housing (5). Appplication to the decontamination of medical waste materials.
Patent AT-E222290-T1 (AT)
Inventor: HANECAK RONNIE C
IPC: C12N15/09
Filed: 1993-09-29
Granted: 2002-08-15
Abstract: Modified oligonucleotides having a conserved G4 sequence and a sufficient number of flanking nucleotides to significantly inhibit the activity of a virus such as HSV-1 or phospholipase A2 or to modulate the telomere length of a chromosome are provided. G4 quartet oligonucleotide structures are also provided. Methods of prophylaxis, diagnostics and therapeutics for viral-associated diseases and diseases associated with elevated levels of phospholipase A2 are also provided. Methods of modulating telomere length of a chromosome are also provided; modulation of telomere length is believed to play a role in the aging process of a cell and in control of malignant cell growth.
Patent AT-E196102-T1 (AT)
Inventor: DRUMMOND HUMPHREY JOHN JARDINE
IPC: G01N29/14
Filed: 1993-10-27
Granted: 2000-09-15
Abstract: PCT No. PCT/AU93/00556 Sec. 371 Date Aug. 22, 1995 Sec. 102(e) Date Aug. 22, 1995 PCT Filed Oct. 27, 1993 PCT Pub. No. WO94/09890 PCT Pub. Date May 11, 1994A failed hollow fiber is located in a membrane filtration module by supplying a gas under pressure to the space between fibers and shell, wetting the ends of fibers, and monitoring the ends of the fibers for bubble formation.
Patent AT-E157618-T1 (AT)
Inventor: BOURBOULOU YVES
IPC: A61J1/00
Filed: 1993-11-02
Granted: 1997-09-15
Abstract: PCT No. PCT/SE93/00915 Sec. 371 Date Jun. 30, 1995 Sec. 102(e) Date Jun. 30, 1995 PCT Filed Nov. 2, 1993 PCT Pub. No. WO94/10064 PCT Pub. Date May 11, 1994The present invention is directed to the method and use of a helium containing gas for improving the physical stability of packaged sensitive products, especially those products which contain a fat emulsion.
Patent AT-E168916-T1 (AT)
Inventor: DORNIEDEN GEORG DIPL-ING
IPC: B23P21/00
Filed: 1994-07-23
Granted: 1998-08-15
Abstract: Assembly system with a machine frame, a circular plate fixed to the machine frame, and a supporting plate concentric with respect to the circular plate and rotationally driven in timed sequence. The radius of the supporting plate is greater than that of the circular plate. The supporting plate has a work-supporting ring at its outer margin and is arranged under the circular plate with merely a gap in between. The work-supporting ring as well as the work stations on the circular plate are driven by means of a single motor/gear arrangement which is driven continuously. The motor/gear arrangement works on the supporting plate by means of a toothed-belt drive via a dwell/step-by-step motion linkage. The motor/gear arrangement works on the individual work stations via a control shaft with mounted cam plates as well as pull/push actuating elements actuated by the cam plates. The pull/push actuating elements in the centre of the assembly system are attached to the work stations through corresponding recesses in the supporting plate and in the circular plate. <IMAGE>
Patent AT-E166943-T1 (AT)
Inventor: DODD GRAHAM SYDNEY
IPC: E06B3/36
Filed: 1994-01-11
Granted: 1998-06-15
Abstract: The invention relates to a door, a fanlight, door side section (door side light), window or similar, characterised by two glass sheets arranged beside one another at a distance, by a frame holding the sheets at a distance from one another - preferably incorporating fittings for the door etc., said frame essentially being covered by the sheets, by sealing means for the hermetic sealing of the space enclosed by frame between sheets and by a dessicant communicating with this space. <IMAGE>
Patent AT-E167853-T1 (AT)
Inventor: GYLYS JONAS A
IPC: A61K31/40
Filed: 1994-09-14
Granted: 1998-07-15
Abstract: Substd. cyclobutene dione cpds. of formula (I) and their acid addition salts and/or solvates are new. R1 is H, halogen or 1-4C alkyl; R2 and R3 are H or 1-4C alkyl; R4 is H, 1-4C alkyl, 1-4C acyl or 1-4C alkylsulphonyl; X is -NR2R3, -OR2 or R6 where R6 is H, 1-4C alkyl, cycloalkyl, phenyl or phenyl-(1-4C)alkyl); m is 0-3 (esp. 0); n is 1-5(esp. 2).
Patent AT-E197899-T1 (AT)
Inventor: RAULT ISABELLE
IPC: A61K9/70
Filed: 1994-09-15
Granted: 2000-12-15
Abstract: Bioadhesive pharmaceutical composition for the controlled release of active principles locally through the buccal cavity or systemically through a mucous membrane, characterised in that it is composed of an active principle, of a compound (A), of a compound (B) and of excipients as defined in the description.
Patent AT-E168594-T1 (AT)
Inventor: PETERSON ROBERT JAMES
IPC: B05B11/00
Filed: 1994-04-18
Granted: 1998-08-15
Abstract: A liquid dispensing pump (20) for use with consumer product packages is provided with a shipping seal. The housing of the pump device includes an upper housing (24) and a lower housing (26) which are movable relative to each other between open and closed shipping seal positions. The liquid dispensing pump (20) includes a collapsible pump chamber (40), e.g. a bellows. Integral with the bellows (40) is at least one functional element of the shipping seal. The housing includes cooperating actuation elements which prevent actuation of the pump device when the shipping seal is closed. The housing may also include a tamper evident device which prevents actuation of the pump device prior to removal of the tamper evident tab; and may prevent movement of the housing from the closed shipping seal position to the open shipping seal position prior to removal thereof. The bellows (40) may also include an integral valve including a valve member, a valve seat and a valve opening which are all integral components of a wall of the collapsible pump chamber (40), the valve seat facing one side of the wall and the valve member being formed at an angle away from the other side of the wall so that upon pushing the valve member through the valve opening the valve member is biased against the valve seat.
Patent AT-E181009-T1 (AT)
Inventor: PFLAGER WILLIAM W
IPC: B24B19/12
Filed: 1994-07-21
Granted: 1999-06-15
Abstract: A method of forming a hydrostatic nut that cooperates with a lead screw for translating a wheel head, or carriage, on a grinding machine, such as a cam grinder. A lead screw standard, or master, which is externally threaded, is inserted into a cylindrical mold, which is internally threaded. The standard is retained therein by pressure plates that seal off opposite ends of the open bore of the mold. Beads of wax, or tape, or some other rigid instrumentality, are adhered to the exterior surfaces of the helical threads on the standard, while the rest of the standard is treated with a release coating. A continuous cavity is defined between the internal threads on the nut and the external threads on the standard. An epoxy resin or other castable polymer is introduced through an inlet port in the mold into the cavity. The castable polymer is allowed to cure into a rigid mass that adheres to the internal threads on the mold except for the helical beads. The standard is removed, the mold is machined to its final configuration as a hydrostatic nut, and the wax, or tape, is removed to leave voids in the rigid cured polymer. The voids define oppositely directed helical channels that are pressurized to form a thin fluid film that prevents metal to metal contact between the complementary helical threads on the nut and lead screw. The cured polymeric mass is structurally reinforced by the threads defined on the metal nut, so that the channels defined on the exterior surface thereof maintain their dimensions.
Patent AT-E239784-T1 (AT)
Inventor: O'NEILL KIM L
IPC: C07K16/40
Filed: 1994-08-05
Granted: 2003-05-15
Abstract: Thymidine kinase 1 (TK1) activity in a sample is detected by contacting a monoclonal antibody to active TK1 with the sample, and determining the amount of the monoclonal antibody bound to active TK1. A method of predicting recurrence of a tumor in a patient comprises the steps of establishing a normal range for thymidine kinase 1 (TK1) activity, determining the amount of TK1 activity in a sample from a cancer patient, and comparing the value of the normal range for TK1 activity with the TK1 activity in the sample from the cancer patient, wherein when said TK1 activity from the cancer patient significantly exceeds the normal range for TK1 activity it is predicted that the tumor is likely to recur.
Patent AT-E176906-T1 (AT)
Inventor: SHUDO KOICHI
IPC: C07D245/06
Filed: 1994-09-22
Granted: 1999-03-15
Abstract: A benzolactam derivative represented by the following formula (I):   <CHEM> wherein n represents an integer of from 1 to 3; R<1> represents a straight- or branched-chain alkyl group or an aralkyl group; R<2> represents a straight- or branched-chain alkyl group; R<3> and R<4> independently represent a hydrogen atom or a straight- or branched-chain alkyl group, and when R<3> and R<4> are adjacent each other on the phenyl group, they may be combined to form a cycloalkyl ring together with two carbon atoms of the phenyl group to which R<3> and R<4> bind, and said cycloalkyl ring may optionally have one or more substituents; and a anti-retroviral agent comprising the same as an active ingredient.
Patent AT-E144440-T1 (AT)
Inventor: OLSCHEWSKI BRIGITTE DR
IPC: C11D3/38
Filed: 1994-10-01
Granted: 1996-11-15
Abstract: The invention pertains to a mixture of surface active compounds that are produced from microbial biomasses and natural fats and/or oils as well as low-molecular organic compounds that regulate the chain length as well as the HLB value of the individual components of the mixture, the reaction being carried out in an aqueous medium and in the presence of a catalytic agent. These mixtures can be used as essentially nonionic surfactants having an anionic portion, for example as cleaning or foaming agents; as emulsifiers for a wide variety of organic substances in water, thus for oil-in-water emulsions, and furthermore as wetting agents in the broadest sense.
Patent AT-E166094-T1 (AT)
Inventor: ZOLK RALF DR
IPC: C08F4/642
Filed: 1995-02-24
Granted: 1998-05-15
Abstract: New propylene polymer contg. 0.01-1.5 pts.wt. nucleating agent (B) per 100 pts.wt. propylene homopolymer (A) with a melt flow index of 5-25g/10 minutes at 230 degrees C and 2.16 kg load (ISO 1133), and an isotacticity index of at least 98%. Also claimed is the prepn. of the polymer by combining (A) and (B) in a mixing appts. at 200 - 250 degrees C.
Patent AT-E167566-T1 (AT)
Inventor: GRESENS HARRY
IPC: F26B21/00
Filed: 1995-03-13
Granted: 1998-07-15
Abstract: The air cleaning system has the air stream used for treatment of the textile web fed through an endless filter mesh (6) at the input side of the ventilator fan, with the fibres etc. captured by the filter mesh periodically removed by a suction jet device (11). Pref. the soiling level of the filter mesh surface is monitored, to activate the suction jet device for removing the deposits on the outside of the filter mesh, when the detected soiling level reaches a threshold value.
Patent AT-E157309-T1 (AT)
Inventor: SCHWENDT LUTZ
IPC: B61C17/04
Filed: 1995-03-21
Granted: 1997-09-15
Abstract: The vehicle has guide rails (18) for the side windows (12). The rails are pivoted and may be locked in a closed position. They are actuated and locked via a lever transmission (24), e.g. a toggle lever arrangement. The side window may be locked in positions between max. opening and closed position. In intermediate positions, it is locked by positive engagement of the window on a retainer profile. This consists of an elastic material, e.g. rubber.
Patent AT-E194089-T1 (AT)
Inventor: DANNEVANG FLEMMING
IPC: C01B21/26
Filed: 1995-09-25
Granted: 2000-07-15
Abstract: In a process for the catalytic low temperature oxidation of ammonia to nitrogen in an ammonia containing off-gas at a temperature of between 200<o>C and 500<o>C the improvement comprises, sulphating a catalyst comprising on an inert carrier a metal selected from the group of copper, cobalt, iron, chromium, nickel, manganese and mixtures thereof in the form of their oxides and/or sulphates and a further component selected from the group of platinum metals; contacting the ammonia containing atmosphere with the catalyst, and  withdrawing a decomposed gas being rich in nitrogen.