baber/WOPTO huggingface dataset:
Patent DE-69411317-D1 (DE)
Inventor: KOJIMA ATSUYUKI
IPC: C07D209/42
Filed: 1994-04-28
Granted: 1998-08-06
Abstract: Novel indoloylguanidine derivatives of the following formula (I), and pharmaceutically acceptable salts thereof, inhibit the Na<+>/H<+> exchanger activity and are therefore useful in the treatment and prevention of disease caused by increased Na<+>/H<+> exchanger activity. <CHEM>  wherein each R1, which may be the same or different, is independently selected from hydrogen, an alkyl group, a substituted alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a halogen, a nitro group, an acyl group, a carboxyl group, an alkoxycarbonyl group, an aromatic group, and a group of formula: -OR3, -NR6R7, -SO2NR6R7 or -S(O)nR40; R2 is a hydrogen atom, an alkyl group, a substituted alkyl group, a cycloalkyl group, a hydroxy group, an alkoxy group or a group of formula -CH2R20; R3 is hydrogen, an alkyl group, a substituted alkyl group, a cycloalkyl group or a group shown by formula: -CH2R30, wherein R30 represents an alkenyl group or an alkynyl group; each of R6 and R7, which may be the same or different, is independently selected from hydrogen, an alkyl group, a substituted alkyl group, a cycloalkyl group, an acyl group and a group of formula: -CH2R60, wherein R60 represents an alkenyl group or an alkynyl group; or R6 and R7, together with the nitrogen atom to which they are attached, form a saturated 5- to 7- membered cyclic amino group which optionally includes at least one other hetero atom in the ring;     R40 is an alkyl group or a substituted alkyl group;     n is 0, 1 or 2;  and,     R20 is an alkenyl group or an alkynyl group; and wherein the substituents R1 and the guanidinocarbonyl group -C(=O)-N=C(NH2)2 are each, independently, attached to any one of the 5- and 6- membered rings of the indole nucleus; or a pharmaceutically acceptable acid addition salt thereof.
Patent DE-69417101-D1 (DE)
Inventor: BEUKERS A
IPC: B29D22/00
Filed: 1994-05-26
Granted: 1999-04-22
Abstract: The invention is directed to an inflatable body, such as a lifting body, comprising a fiber reinforced elastomer body which is flat in unflated condition and has in inflated condition a mechanical equilibrium shape that is predominantly geometrically continuous, non-spherical and non-cylindrical. <IMAGE>
Patent DE-69425051-D1 (DE)
Inventor: BRANDT KIM
IPC: E04B1/76
Filed: 1994-01-14
Granted: 2000-08-03
Abstract: A method of producing a mineral fiber-insulating web comprises the steps of firstly producing a first non-woven mineral fiber-web being a loosely compacted mineral fiber web of a low area weight, such as an area weight of 50-1500 g/m2, e.g. 100-1200 g/m2, such as 200-600 g/m2, or 600-1200 g/m2. The first mineral fiber web contains mineral fibers arranged generally in the longitudinal direction of the mineral fiber web. Secondly, the first mineral fiber web is moved in the longitudinal direction of the web and folded transversely relative to the longitudinal direction and parallel with a transversal direction of the first mineral fiber web, so as to produce a second mineral fiber-web containing mineral fibers arranged generally perpendicular to the longitudinal and transversal directions. Thereupon, the folded mineral fiber web is cured for bonding the mineral fibers together so as to produce the mineral fiber-insulating web comprising a central body containing mineral fibers arranged generally perpendicular to the longitudinal direction of the mineral fiber web. The method also optionally includes longitudinally compressing and/or transversally compressing the folded mineral fiber web. The folded mineral fiber web may additionally be combined with additional mineral fiber webs or coverings for producing a composite mineral fiber web product which is cured in a single curing process.
Patent DE-69427079-D1 (DE)
Inventor: JONES F
IPC: E02F9/28
Filed: 1994-02-02
Granted: 2001-05-17
Abstract: An excavating tooth (10) for use on a wide variety of excavating equipment is comprised of a point (12), an adapter (14) and a sandwich lock pin (16). The pin includes a rigid casing (54) and a plurality of independently depressible protrusions (58, 59). One of the protrusions (58) resiliently engages a face (22) defined on the nose of the adapter to tighten the connection of the point on the nose. One other of the protrusions (59) extends into an opening (50) defined by the point to secure the lock pin to the point. With respect to an external locking tooth, the opening (50) defined in the point includes a pair of bosses (155a, 155b) which define a reduced portion of the opening. The reduced portion matingly receives and holds the ends of the rigid casing of the pin. The independent locking of the pin and the mating receipt of the casing in the point opening reduces the likelihood of pin loss due to overloading of the elastomeric material, wearing of the components or jacking forces.
Patent DE-69517930-D1 (DE)
Inventor: MARCO WILLIAM
IPC: C09J119/00
Filed: 1995-06-15
Granted: 2000-08-17
Abstract: An aqueous adhesive composition for bonding reinforcing textiles to rubber products is provided, having an epoxy resin with a functionality of three or greater and a rubber latex functionalized with pendent groups selected from carboxyl, amide and pyridyl groups.
Patent DE-69517985-D1 (DE)
Inventor: DABBAJ RAD H
IPC: H01J31/24
Filed: 1995-09-01
Granted: 2000-08-17
Abstract: PCT No. PCT/GB95/02061 Sec. 371 Date May 13, 1997 Sec. 102(e) Date May 13, 1997 PCT Filed Sep. 1, 1995 PCT Pub. No. WO96/08031 PCT Pub. Date Mar. 14, 1996A light valve modulator of reflective operation which includes a multi-layer structure which is controlled electrostatically, comprises a transparent substrate supporting a first transparent deformable layer and a second insulating dielectric deformable layer, with a mirror layer sandwiched between, and a third, dielectric insulating layer on the outside of the second layer, at least one of the layers between the second layer and the substrate being electrically conductive, and the third dielectric layer being capable of receiving an electric charge pattern by means of one or more electron beams, whereby the mirror layer is locally deformed by electrostatic forces occurring between the third layer and the conductive layer. The twin deformably layers allow good sensitivity, while the outside dielectric layer which receives charge from an electron beam protects the deformable layers from electron bombardment and the cathode from outgassing. The modulator is for use in display tubes, particularly for projection TV.
Patent DE-69522744-D1 (DE)
Inventor: BARAN GEORGE
IPC: A61M15/00
Filed: 1995-06-19
Granted: 2001-10-25
Abstract: An improved system for delivery of an aerosolized medicine to a patient's respiratory system. The system uses a pressurized canister that contains a mixture of a medicine and a propellant which may be in a liquid state. The canister has an outlet from which the mixture can exit. The system includes an extension catheter that connects at a proximal end to the outlet of the canister. The extension catheter has a length such that a distal end can be positioned either in an endotracheal tube or deep in the respiratory tract of the patient while the proximal end of the extension catheter is connected to the canister which is located outside the patient's body. The extension catheter includes at least one lumen extending therethrough for conveying the medicine and liquid propellant mixture from the canister to a distal exit orifice where an aerosol can be generated as the propellant evaporates. The aerosolized medicine is carried by the patient's inhalation and delivered to the lungs. The extension catheter may be positioned in an endotracheal tube or alternatively may be used with a patient who is not intubated. <IMAGE>
Patent DE-69523179-D1 (DE)
Inventor: BERTINA ROGIER MARIA
IPC: C12Q1/6883
Filed: 1995-02-14
Granted: 2001-11-15
Abstract: Method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C (APC). The method is directed at detecting one or more mutations at one or more of the cleavage and/or binding sites for APC of Factor V and/or Factor Va or at Factor VIII and/or Factor VIIIa at either nucleic acid or protein level or both.
Patent DE-69527787-D1 (DE)
Inventor: BRIGHTWELL IAN
IPC: C07D401/12
Filed: 1995-06-01
Granted: 2002-09-19
Abstract: Compounds having the formulawhere R2 is a heteroaryl group linked to the remainder of the molecule via a carbon atom adjacent a nitrogen atom and R4 and R5 are both hydrogen atoms or together represent -SO- or -SO2- and A is C2-C4 alkylene optionally substituted by one or more lower alkyl groups are novel intermediates in the preparation of pharmaceutically useful piperazine derivatives as end compounds. The compounds having formula V where R4 and R5 are hydrogen may be prepared by a rearrangement of a compound having the formula (VI).
Patent DE-69528412-D1 (DE)
Inventor: GOTO TEIYU
IPC: A63F13/245
Filed: 1995-05-09
Granted: 2002-11-07
Abstract: A controller unit for controlling an electronic device such as a video game. The controller unit comprises a housing (3) on which a control section (9) is mounted, said control section (9) comprises a key body (12) with a plurality of integral key elements (14a, 14b, 14c, 14d) and having a first semispherical recess (15) on its bottom and a second semispherical recess (16) on its top, a spherical fulcrum member (20) located below the key body and engageable with the first recess (15), a resilient body (18) disposed between the key body (12) and the housing and including movable electrical contacts (19A), and a semispherical projection (23) engageable with the second recess (16) and being centrally located at the key body (12). <IMAGE>
Patent DE-69605625-D1 (DE)
Inventor: SPENDEL KARL DAMIAN
IPC: G07F15/00
Filed: 1996-09-09
Granted: 2000-01-20
Abstract: A gas meter comprising a meter housing, a gas volume measuring system and a valve, wherein the valve and the system are both contained within the housing, an inlet pipe, via which gas is supplied to the system and the valve, and an outlet pipe via which the gas supplied to the system and the valve is fed to a consumer, a first communication port, operatively associated with the system, via which data signals appertaining to gas supplied to a consumer via the outlet pipe are transmittable, the housing being adapted contiguously to receive a module which is effective to provide predetermined meter functionality, which module comprises a further communication port positioned for communication with the system via the said first communication port. <IMAGE>
Patent DE-69610628-D1 (DE)
Inventor: CLAREMON A
IPC: C07D243/12
Filed: 1996-06-03
Granted: 2000-11-16
Abstract: This invention is concerned with novel compounds represented by structural formula I    <IMAGE>  FORMULA I  which are useful in the treatment of arrhythmia.
Patent DE-69613383-D1 (DE)
Inventor: GORETA LUCAS
IPC: H04W28/06
Filed: 1996-09-25
Granted: 2001-07-19
Abstract: Disclosed is a method enabling the generation, by means of voice frequencies, of a sequence of several characters and the high-speed transmission of these characters. This method comprises the step of the elimination, during transmission, of the blanks between two successive characters when these characters are distinct or are encoded distinctly.
Patent DE-69622164-D1 (DE)
Inventor: BROOKS KEVIN
IPC: H02G5/00
Filed: 1996-03-15
Granted: 2002-08-08
Abstract: A length of busbar 1 carries elongate conductors 2,3,4,5 extending beyond the end of said length and straddled by two side plates 6 and 7 which provide means on which a cover may be mounted. The side plates 6,7 are fastened to a known joint pack 2 for joining conductor lengths, with said plates extending into slots 9,10 of the pack and with plate flanges 6f, 7f attached to the bus bar. Two further side plates 6a, 7a straddle adjoining conductor lengths. The joint area is protected by the cover which is mounted to the side plates on angle brackets or by cover flanges engaging plate regions 12, 12b. Lengths of busbar are interconnected by self-piercing rivets.
Patent DE-69623272-D1 (DE)
Inventor: BRENTANI R
IPC: C07K7/08
Filed: 1996-04-11
Granted: 2002-10-02
Abstract: The invention involves an isolated anti prion protein binding protein which has a molecular weight of from about 55 kD to about 65 kD as determined by SDS-PAGE. Also described is a peptide derived from this isolated anti-prion protein binding protein. Diagnostic uses for each of these molecules are discussed.
Patent DE-69626987-D1 (DE)
Inventor: FERGUSON WILLIAM
IPC: A61K31/7024
Filed: 1996-07-31
Granted: 2003-04-30
Abstract: The present invention concerns analogues of Mannose-6-phosphate for use in promoting the healing of wounds or fibrotic disorders with reduced scarring.
Patent DE-69633565-D1 (DE)
Inventor: FALLAUX JACOBUS
IPC: C12N5/08
Filed: 1996-06-14
Granted: 2004-11-11
Abstract: The invention provides improved methods and products based on adenoviral materials which can advantageously be used in for instance gene therapy. In one aspect an adenoviral vector is provided which has no overlap with a suitable packaging cell line which is another aspect of the invention. This combination excludes the possibility of homologous recombination, thereby excluding the possibility of the formation of replication competent adenovirus. In another aspect an adenovirus based helper construct which by its size is incapable of being encapsidated. This helper virus can be transferred into any suitable host cell making it a packaging cell. Further a number of useful mutations to adenoviral based materials and combinations of such mutations are disclosed, which all have in common the safety of the methods and the products, in particular avoiding the production of replication competent adenovirus and/or interference with the immune system. Further a method of intracellular amplification is provided.
Patent DE-69637021-D1 (DE)
Inventor: KRISTIPATI RAMASHARMA
IPC: C07K14/435
Filed: 1996-06-26
Granted: 2007-05-24
Abstract: Disclosed is the use of an omega-conopeptide in the manufacture of a medicament for inhibiting progression of neuropathic pain disorders.
Patent DE-69702388-D1 (DE)
Inventor: THEBRIN INGEMAR
IPC: D04H1/425
Filed: 1997-03-21
Granted: 2000-08-03
Abstract: A method in which a sheet of cellulosic fibres is shredded into fluff wherein, prior to shredding, the fibres are treated in the presence of water with a hydrophobic substance having a specific surface area of at least about 50m<2>/g, to yield improved sorptive capacity; fluff obtainable by the method, absorbent articles comprising such fluff; use of a substance of said kind for improving the sorptive capacity of absorbent material comprising the fibres; a process for production of absorbent material obtained by shredding a sheet of such fibres in which the fibres, prior to shredding, have been treated in the presence of water with a substance of said kind to yield improved sorptive capacity; and absorbent material obtainable from the process.
Patent DE-69709143-D1 (DE)
Inventor: ALAMI MOUAD
IPC: B01J31/16
Filed: 1997-09-08
Granted: 2002-01-24
Abstract: The subject-matter of the invention is a process for the preparation of o-(p-tolyl)benzonitrile, characterized in that an o-halobenzonitrile is treated with a p-tolylmagnesium halide in the presence of a manganous salt and of a cocatalyst comprising a transition metal.
Patent DE-69714046-D1 (DE)
Inventor: BUAZZA OMAR M
IPC: B29C39/02
Filed: 1997-04-18
Granted: 2002-08-22
Abstract: Method for making a plastic lens is provided. More particularly, a method for applying alternating periods of ultraviolet light to a lens forming composition is described. The lens forming composition is cured while controlling the rate of heat generation and/or dissipation via manipulation of the duration of the ultraviolet light or the cooling in the curing chamber. The ultraviolet light is preferably directed toward the lens forming composition which is disposed in a mold cavity formed by two mold members. The ultraviolet light may be directed in pulses or continuously.
Patent DE-69722204-D1 (DE)
Inventor: HYVOENEN HEIMO
IPC: E02D29/12
Filed: 1997-06-24
Granted: 2003-06-26
Abstract: Two types of service units (5 and 10) are used in district heating establishments, arranged in shafts requiring a person to descend into the shaft. According to the invention the service units (5 and 10) are moved from a road surface (1) to a level (2) at the side and other service units (5 and 10) are created enabling manipulation at ground level (2) in an erect position. One service unit is arranged specially for connection to a property.
Patent DE-69723456-D1 (DE)
Inventor: RODGERS JAMES DAVID
IPC: C07D403/06
Filed: 1997-11-04
Granted: 2003-08-14
Abstract: The present invention relates to compounds of formulae (I) and (II), or pharmaceutically acceptable salt forms or prodrugs thereof, which are useful as inhibitors of HIV protease, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.
Patent DE-69737423-D1 (DE)
Inventor: WING MALCOLM J
IPC: G06F12/08
Filed: 1997-09-22
Granted: 2007-04-12
Abstract: Apparatus and a method for storing data already stored at an often utilized memory address in registers local to a host processor and maintain the data in the registers and memory consistent so that the processor may respond more rapidly when a memory address is to be accessed.
Patent DE-69737695-D1 (DE)
Inventor: CINELLI FABIO
IPC: A61K8/86
Filed: 1997-12-22
Granted: 2007-06-14
Abstract: The present invention relates to topical adhesives for attachment to the skin. In particular the present invention relates to such topical adhesives which can be employed for attachment to the skin of protective articles, clothing, prosthesis, heat wraps, pads, and/or packs, e.g. for topical relief of pain or simply to provide warmth; cold wraps, hearing aids, protective face masks, ornamental articles, or eye wear but excluding absorbent articles. The topical adhesive provides secure attachment and is pleasing to the skin upon application, yet causes no discomfort upon removal. This is achieved by selecting the chemical composition and rheological characteristics of the topical adhesives.
Patent DE-69803921-D1 (DE)
Inventor: BERNARD FREDERIC
IPC: B65G47/64
Filed: 1998-04-08
Granted: 2002-03-28
Abstract: A route switching apparatus for conveying articles, including a plurality of lines suitable for conveying the articles along respective separate paths and a body having a polygonal cross-section and pivotable about a longitudinal axis. The body is positioned along the plurality of lines between an entry and an exit of the lines. The body has a plurality of lateral faces with transfer lines formed on respective lateral faces. The transfer lines communicate with respective lines of the plurality of lines between the entry and the exit. The body is pivotable such that the transfer lines can communicate with different respective lines so that the articles moving along one of the separate paths can transfer to another of the separate paths.
Patent DE-69803948-D1 (DE)
Inventor: YOSHII HIROYUKI
IPC: H01B7/00
Filed: 1998-03-23
Granted: 2002-04-04
Abstract: A conductor (42a) of an audio pin cable is electrically and mechanically connected at both ends thereof to the terminals inside of pin plugs (41a, 45a). A vibration attenuating member such as a cross section-enlarging member (43a) is joined at the middle portion of the conductor (42a) . The conductor (42a) and the cross section-enlarging member (43a) are coated around the periphery with an insulating member (44a). When a longitudinal wave passes through the conductor (42a), the cross section-enlarging member (43a) attenuates the longitudinal vibration transmission through the audio pin cable, thus achieving reproduced sounds as close to the original sounds as possible. <IMAGE>
Patent DE-69804185-D1 (DE)
Inventor: JODET GERARD
IPC: F27B9/28
Filed: 1998-10-07
Granted: 2002-04-18
Abstract: Rapid-cooling oven, forming part of a plant comprising various treatment stations, especially stations for the heat treatment of products in strip form, through which a metal strip runs continuously, the rapid cooling being obtained by spraying onto the strip a jet of an atmosphere gas consisting of a nitrogen/hydrogen mixture having a hydrogen content which is greater than 15%, and preferably close to 50%, the atmosphere gas being recirculated using a circuit of recirculation ducts comprising compensators made in the form of a series of corrugations allowing all the ducts to expand, at least one fan and at least one gas/water exchanger, wherein a safety device is provided to prevent this ingress of air into the circuit for recirculating the cooling gas or any leak of the latter into the environment, in the event of a break in a corrugation of a compensator or in the case of a leak form the latter, said safety device being made in the form of a flexible membrane impermeable to the cooling gas, the said membrane being placed around each of the compensators of the recirculation duct, a means being furthermore provided for immediately interrupting the flow of the cooling gas in its recirculation circuit.
Patent DE-69806883-D1 (DE)
Inventor: POWELL JAMES A
IPC: B29C49/04
Filed: 1998-10-15
Granted: 2002-09-05
Abstract: A clean air duct (300) comprises a pair of tubular bodies (302, 310), each tubular body having a pair of opposed ends (304, 306, 312, 314), one of the opposed ends of one tubular body having an annular ring (346) which terminates at an inwardly extending lip (340), the other tubular body having an outwardly extending rib (322) at one end; and a cuff (320) connecting the outwardly extending rib and the inwardly extending lip. Another clean air duct (400) comprises a first blow molded tubular body (406) having a first open end (408) and an annular ring (450) which terminates at an inwardly extending lip (444), and a second blow molded tubular body (402) which has an open end (404). A cuff (412) connects the blow molded tubular bodies to one another wherein the lip (444) exerts a compressive sealing force around the second tubular body (402). Both tubular bodies (402, 406) extend from the cuff (412) in the same direction. <IMAGE>
Patent DE-69811697-D1 (DE)
Inventor: CARLSSON PERVI
IPC: B21D28/28
Filed: 1998-06-02
Granted: 2003-04-03
Abstract: The invention relates to a method of punching one or more holes in a two-wall workpiece having mutually facing walls where one or more holes is/are to be punched in at least one wall. According to the method, there is inserted in the space between the walls a punch die that has a thickness corresponding essentially to the distance between the walls. The die includes one or more punch cavities. A punch tool having one or more punches is activated on the ouside of the wall subsequent to having moved the punch die to a position in which a punch cavity is located opposite its respective punch. The invention also relates to a punch die (8) for use when carrying out the method. The punch die (8) includes one or more punch cavities (7) and is adapted for insertion into the space between the wall (2, 3) of the two-wall workpiece (1).
Patent DE-69813552-D1 (DE)
Inventor: PALUMBO GIANFRANCO
IPC: A61F5/451
Filed: 1998-06-26
Granted: 2003-05-22
Abstract: The present invention relates to a faecal management device with an increased level of comfort. The faecal management device comprises a bag having an aperture, and an anatomically-shaped flange, which surrounds the aperture. The flange provides for adhesive attachment to the perianal area of the wearer. In particular, the bag comprises a wall material having an inner surface and an outer surface with the outer surface being provided with a non-woven layer. In another aspect of the present invention, the faecal management device is used in combination with a disposable diaper. <IMAGE>