baber/WOPTO huggingface dataset:
Patent NZ-596517-A (NZ)
Title: Antibody purification
Inventor: AVGENINOS GEORGE
IPC: A61K39/395
Filed: 2007-04-04
Abstract: NZ 596517 Disclosed is a pharmaceutical composition comprising an isolated human anti-TNF? antibody that dissociates from human TNF? with a Kd of 1x10-8M or less and a Koff rate constant of 1x10-3s-1 or less, both determined by surface plasmon resonance, and neutralises human TNF? cytotoxicity in a standard in vitro L929 assay with an IC50 of 1x10-7 M or less, and a pharmaceutically acceptable carrier, wherein the composition contains a level of HCP no greater than 70ng of HCP per mg of antibody as measured by an HCP ELISA and a cathepsin L activity of no greater than 3.0 RFU/s/mg antibody.
Patent NZ-596965-A (NZ)
Title: Methods for the production of functional protein from dna having a nonsense mutation and the treatment of disorders associated therewith
Inventor: ALMSTEAD NEIL G
IPC: A61K31/00
Filed: 2007-03-29
Abstract: 596965 Disclosed is the use of a compound having the formula defined herein, or a pharmaceutically acceptable salt, solvate or hydrate thereof, in the treatment of cystic fibrosis, wherein the subject has a nonsense mutation in the codon corresponding to position 414, 493, 1316, 553, 542, 1162,122, 1455, 822, 60, 764, 1291, 849, 434, 88, 1158 or 6542 of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Specific embodiments of the compound include: 3-[S-2-fluoro-phenyl-[1,2,4]oxadiazol-3-yl]-benzoic acid (PTC124).
Patent NZ-597682-A (NZ)
Title: Epsps mutants
Inventor: GOCAL GREG F W
IPC: A01H5/00
Filed: 2007-01-10
Abstract: Patent No. 597682 Disclosed is method for producing a non-transgenic, herbicide resistant or tolerant plant comprising: introducing into plant cells a recombinagenic oligonucleobase with a targeted mutation in the EPSPS gene to produce plant cells with a mutant EPSPS gene that expresses an EPSPS protein that is mutated at amino acid positions Thr179 and Pro183in an Arabidopsis EPSPS protein or at an analogous amino acid residue in an EPSPS homolog, wherein Thr179 is changed to Ile and Pro183 is changed to Thr or Ala; selecting a plant cell exhibiting improved tolerance to glyphosate as compared to a corresponding wild-type plant cell; and regenerating a non-transgenic herbicide resistant or tolerant plant having a mutated EPSPS gene from said selected plant cell.
Patent NZ-597827-A (NZ)
Title: A respiratory apparatus with a ribbon or tape heater which humidifies gas in a conduit
Inventor: KLASEK PAUL JAN
IPC: A61M16/06
Filed: 2007-11-08
Abstract: 597827 Disclosed is a respiratory apparatus for delivering breathable gas to a patient. The apparatus has a flow generator to generate a supply of pressurised gas to be delivered to the patient, a humidifier to vaporize water and to deliver water vapour to humidify the gas, a gas flow path leading from the flow generator to the humidifier and from the humidifier to a patient interface, and a heater to thermally contact with water in the humidifier. The heater has an elongate heating filament in the form of a tape.
Patent NZ-600271-A (NZ)
Title: Lyophilization methods, compositions, and kits
Inventor: GUO JIANXIN
IPC: A01N1/02
Filed: 2010-11-23
Abstract: 600271 Describes a method of lyophilizing an active ingredient, being Antithrombin (AT III) and crystallising agent selected from alanine, mannitol, glycine or sodium chloride, wherein the method involves exposing the composition to a first temperature for a first period of time sufficient to obtain a first composition having at least one crystallizing excipient partially or completely crystallized.
Patent NZ-601358-A (NZ)
Title: Biaryl pde4 inhibitors for treating pulmonary and cardiovascular disorders
Inventor: SINGH JASBIR
IPC: C07D207/16
Filed: 2008-11-20
Abstract: 601358 Disclosed are biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula (Ia), (Ib), (Ic) or (Id). Examples of compounds of the invention are 1-[5-(3’-Chloro-2-fluoro-6-methoxy-biphenyl-3-ylmethyl)-1-oxy-pyridin-2-ylmethyl]-3-ethyl-urea; 6-(4-Fluoro-benzyl)-3-methoxy-2-(3-nitro-phenyl)-pyridine 1-oxide and 2-(6-Methoxy-3’-nitro-biphenyl-3-ylmethyl)-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one.
Patent NZ-602889-A (NZ)
Title: Solvent-based fluoropolymer additives and their use in coating compositions
Inventor: BROWN GERALD ORONDE
IPC: C08F20/24
Filed: 2011-05-26
Abstract: Disclosed is a coating composition comprising a 2-propenoic acid, 2-methyl-, perfluoroalkyl ester derived fluoropolymer composition and a coating base, wherein the fluoropolymer composition comprises a fluoropolymer and an organic solvent and further wherein the fluoropolymer comprises repeating units in any sequence of polymer units: I: [Rf-X-Y-C(O)-CZ-CH2]a-; III: [R1-O-C(O)-C(CH3)-CH2]c-; and VI: [R2-O-C(O)-C(CH3)-CH2]g-; wherein Rf is a straight or branched perfluoroalkyl group, which is optionally interrupted by at least one oxygen atom, or a mixture of two or more thereof; X is an organic divalent linking group having from about 1 to about 20 carbon atoms, optionally containing a triazole, oxygen, nitrogen, or sulphur, or a combination thereof; Y is O, S or N(R) wherein R is H or alkyl; Z is a straight or branched alkyl group having from about 1 to about 4 carbon atoms, or halide; R1 is a straight or branched alkyl group having from 12 to 22 carbon atoms; R2 is an alkyl group having a chain length of from 1 to 6 carbon atoms, which carbon chain may branched; a is a positive integer; c is a positive integer; and g is a positive integer; provided that 1) polymer unit I and optional polymer unit II ([Rf-X-Y-C(O)-CH-CH2]b) are present at a minimum combined total of about 30% by weight of the polymer, wherein at least a minimum of about 25% by weight of the polymer is polymer unit I; and 2) the total of all polymer units I, III and VI and optional polymer units II, IV, V and VII (as defined herein) equals 100% by weight of the polymer. Further disclosed is a fluoropolymer obtained by the copolymerisation of 2-propenoic acid, 2-methyl-,3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl ester (of polymer unit I), poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propenyl)-omega-hydroxy- (of polymer unit VII), 2-propenoic acid, 2-methyl-, octadecyl ester (of polymer unit III), 2-propenamide, N-(hydroxymethyl)- (of polymer unit VII), 2-propenoic acid, 2-methyl-, 2-hydroxyethyl ester (of polymer unit VII) and 2-methyl-2-propenoic acid, 2-ethylhexyl ester (of polymer unit VI).
Patent NZ-603460-A (NZ)
Title: Isotope production method
Inventor: KARLSON JAN ROGER
IPC: A61K51/02
Filed: 2011-04-29
Abstract: Disclosed is a method for the generation of 223Ra of pharmaceutically tolerable purity comprising: - preparing a generator mixture comprising 227Ac, 227Th and 223Ra in a first aqueous solution comprising a first mineral acid; - loading said generator mixture onto a DGA separation medium; - eluting said 223Ra from said DGA separation medium using a second mineral acid in a second aqueous solution to give an eluted 223Ra solution; and - stripping the DGA separation medium of said 227Ac and 227Th by flowing a third mineral acid in a third aqueous solution through the DGA separation medium in a reversed direction.
Patent NZ-607844-A (NZ)
Title: Pump systems and methods for storing and dispensing a plurality of precisely measured unit-doses of imiquimod cream
Inventor: NORDSIEK MICHAEL T
IPC: B67B5/00
Filed: 2011-08-05
Abstract: Disclosed herein is a system for treating a subject diagnosed with a dermal and/or mucosal-associated condition, said system comprising: a dispensing package that includes: - a lower subassembly that has a tubular body portion that defines an elongated interior fluid storage chamber into which a take-up piston element is slidably disposed; and - an upper subassembly mounted upon the lower subassembly and including a dispensing head and an airless pumping mechanism, the dispensing head having an internal dispensing duct formed therein which terminates in a self-closing outlet, the dispensing head also including a finger-operated actuator which is operatively associated with the airless pumping mechanism; and an imiquimod cream formulation disposed at least partially within the fluid storage chamber defined in the tubular body portion of the lower subassembly of the dispensing package, and wherein operation of the finger-operated actuator causes the airless pumping mechanism to withdraw a portion of the imiquimod cream formulation from within the interior chamber and to dispense the imiquimod cream formulation into the internal dispensing duct formed in the dispensing head wherein the pressure of dispensed cream causes the self-closing outlet to open thereby discharging a predefined effective unit dose amount of imiquimod cream from the dispensing package. The dermal and mucosal-associated conditions intended to be treated by the system include external genital warts and/or perianal warts (EGWs), actinic keratosis or actinic keratoses (AK or AKs) and superficial basal cell carcinoma (sBCC).
Patent NZ-607969-A (NZ)
Title: Cd33 binding agents
Inventor: KONOPITZKY RENATE
IPC: A61K39/395
Filed: 2011-10-04
Abstract: Disclosed is a CD33 antibody binding to human CD33, the CD33 antibody being defined by binding to an epitope within the amino acid sequence FFHPIPYYDKNSPVHGYW (SEQ ID NO:141) of human CD33. Further disclosed within the specification is the structural antibodies which bind said epitope.
Patent NZ-611171-A (NZ)
Title: Methods and apparatuses for enabling power back-off indication in phr in a telecommunications system
Inventor: BALDEMAIR ROBERT
IPC: H04W52/58
Filed: 2011-04-29
Abstract: A method for use in a user equipment, a method for use in a radio base station and a user equipment and a radio base station are disclosed. The user equipment is configured to decide on application or not of a power reduction and to indicate it decision in a power headroom report intended for transmission to the radio base station. The radio base station is configured to receive the power headroom report and based on the indicated information in the received power headroom report, the base station in made aware of an additional or special power backoff has been applied and thereby able to distinguish it from normal power backoff or power reduction.
Patent NZ-617077-A (NZ)
Title: Processes for preparing jak inhibitors and related intermediate compounds
Inventor: WANG HAISHENG
IPC: C07F7/08
Filed: 2010-01-14
Abstract: The present disclosure is related to processes for preparing intermediates of formula (XII) of chiral substituted pyrazolyl pyrrolo[2,3-di]pyrimidines. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.
Patent NZ-624648-A (NZ)
Title: A timber-working device and method of operation
Inventor: BRETT JAMES KAYE
IPC: A01G23/083
Filed: 2014-05-07
Abstract: Disclosed is a timber harvester head for processing multiple tree trunks together where the speed of opposing or complementary rotary feed wheels are varied according to a controller mode, to allow accurate length measurements of the stems to be carried out. The timber-working device includes a frame that includes a feed axis. A drive system is configured to feed at least one stem along the feed axis, the drive system including first and second drive arms pivotally attached to the frame on respective first and second sides of the feed axis. The first drive arm includes a first rotary drive having a first wheel, and a third rotary drive having a third wheel is mounted on the frame on the first side of the feed axis. The second drive arm includes a second rotary drive having a second wheel, and a fourth rotary drive having a fourth wheel is mounted on the frame on the second side of the feed axis. At least one processor is configured to control operation of the rotary drives, such that in a first mode the speed of the respective wheels of the rotary drives on the same side of the feed axis is substantially the same, and in a second mode the speed of the respective wheels of at least two rotary drives on opposing sides is substantially the same. A method of use and computer code is also disclosed.
Patent NZ-709348-A (NZ)
Title: Machine with two co-axial rotors
Inventor: STANDER JOHAN NICO
IPC: H02K16/02
Filed: 2013-11-15
Abstract: An electromechanical machine having two co-axial and relatively rotatable rotors and a coaxial stator or housing with respect to which both rotors are rotatable about an axis of rotation and wherein rotational movement of one of the rotors relative to the other or relative to the stator or both generates electrical energy. Two bearing arrangements mutually support the two rotors with respect to each other and also support the two rotors with respect to the stator or housing. One of the bearing arrangements comprises multiple support bearings angularly spaced apart with respect to the axis of rotation of the rotors relative to each other and relative to the stator with the support bearings each having an axle or shaft that is fixed relative to one of the rotors or the stator. Each support bearing cooperates with a raceway provided on a concentric adjacent rotor or stator wherein a diameter of the raceway and angular arrangement of the multiple support bearings is greater than the diameter of the other of the two bearing arrangements.
Patent NZ-711285-A (NZ)
Title: Foam dispenser
Inventor: NICMANIS MARK
IPC: B65D83/66
Filed: 2014-02-03
Abstract: The present invention relates to dispenser for producing a foam without requiring the use of liquefied gas, from an outlet. The dispenser (20) comprises a receptacle (37) for holding a surfactant solution (21), means for supplying a gas (23), means for conveying said surfactant solution in said receptacle and said gas along a flow path towards said outlet, wherein said conveying means comprises a conduit having a foaming section (25) for generating said foam from said surfactant solution (21) and said gas (23); and wherein said foaming section (25) has internal dimensions adapted to provide a foam having a quality characterised by predefined limits.
Patent NZ-711551-A (NZ)
Title: Unidirectional multi-path lumber kilns
Inventor: BLOMQUIST CHRISTOPHER W
IPC: F27D3/02
Filed: 2014-03-07
Abstract: Embodiments provide a unidirectional multi-path kiln with two or more chambers and generally parallel flow paths extending through the kiln, on opposite sides, from charge entry portals at a first end of the kiln to charge exit portals at a second end of the kiln. Moist heated air flowing from the second heated chamber is received in the first chamber and circulated around the lumber charges with one or more fans. The lumber charges proceed in the same direction on the flow paths through the heated second chamber, which may be an existing kiln. Charge exit portals at the distal end of the kiln and/or intermediate charge portals between the second chamber and a third chamber may be provided with insulating members configured to reduce airflow from the second chamber through the charge exit portals.
Patent NZ-715001-A (NZ)
Title: Marker for acid sphingomyelinase disorders and uses thereof
Inventor: CHUANG WEI-LIEN
IPC: G01N33/92
Filed: 2014-06-06
Abstract: The present disclosure provides methods of screening, diagnosing, and monitoring the treatment of and/or treating acid sphingomyelinase (ASM) disorders such as Niemann-Pick disease, by using lyso-sphingomyelin as a biomarker. In particular, the methods encompass techniques for improved diagnosis and/or treatment of an ASM disorder, for example using enzyme replacement therapy.
Patent NZ-732608-A (NZ)
Title: Underwater harvesting system
Inventor: SAUE VIDAR
IPC: A01K79/00
Filed: 2015-12-15
Abstract: An underwater harvesting system for harvesting zooplankton while towing, comprising: an underwater vehicle for (2) being lowered into the sea and towed behind a surface vessel (3), comprising a housing provided with an inlet (22) that is variable in size, through which zooplankton-containing-fluid may flow, a hose (4) mounted on the underwater vehicle and in fluid communication with the inlet, the hose adapted to secure and fluidly connect the underwater vehicle to the surface vessel, and pumping means to draw zooplankton-containing-fluid through the inlet and pump it through the hose to the surface vessel. The underwater vehicle further comprises a source of light (6) for emitting light with a predefined wavelength onto a defined water area (7) to facilitate schooling of zooplankton in the illuminated water area. The variable inlet size reduces the drag of the underwater vehicle when towing it through the ocean in search of zooplankton and, when a school is identified, the inlet is opened to increase the reach of the device and improve the catching effect.
Patent NZ-734306-A (NZ)
Title: Resin-coated metal sheet for container
Inventor: YAMANAKA YOICHIRO
IPC: B32B27/36
Filed: 2016-03-25
Abstract: Provided is a resin coated metal plate that is for a container and that allows excellent content removability and is satisfactory in various properties. When the container is molded, the container has a resin layer (A) having a multi-layered structure on the internal surface side and a resin layer (B) on the external surface side. The resin layer (A) contains, as a main ingredient, a polyester of which 85 mol% or more of the acid component which is a constitutional unit of the polyester is a terephthalic acid unit. In the resin layer (A), a resin layer (a1), which is the uppermost layer that makes contact with the content in the container, contains a specific amount of a wax component and has a specific thickness. The Raman-band intensity ratio (I2968/I3085) of the surface of the resin layer (a1) is 0.6-0.9. The resin layer (B) includes a polyester (I) of which the main body is polyethylene terephthalate and a polyester (II) of which the main body is polybutylene terephthalate. The polyester (I) and the polyester (II) are contained at a specific ratio, and the Raman-band intensity ratio of the surface of the resin layer (B) is 0.8-1.0.
Patent NZ-736336-A (NZ)
Title: Increased storage capacity of gas in pressure vessels
Inventor: FANGER GARY
IPC: B60K15/01
Filed: 2016-03-10
Abstract: A gas system includes a container, a fitting, a gas tube, adsorbent, and a filter. The container stores gas under pressure. The fitting covers an opening of the container and maintains a seal with the opening of the container. The gas tube is inserted through a bore in the fitting such that a length of a portion of the gas tube inside of the container is at least one half of a length of the container. The portion of the gas tube in the container includes holes. The adsorbent is in a particulate form and adsorbs gas in the container. The filter covers the holes in the portion of the gas tube in the container. The filter permits passage of gas into and out of the gas tube and prevents passage of the adsorbent into the gas tube.
Patent NZ-747915-A (NZ)
Title: Compact improved bug killing gun
Inventor: MAGGIORE LOREN
IPC: F41B11/80
Filed: 2018-11-02
Abstract: A compact improved bug killing gun includes a compressed gas source fluidly connected to a chamber connected to a barrel. A compressed gas release mechanism is connected to the compressed gas source. A projectile storage magazine stores particulate projectiles and is located adjacent the chamber. A projectile loading mechanism moves the projectiles into the chamber from the magazine. A cocking mechanism is mechanically connected to the compressed gas source, the compressed gas release mechanism, and the projectile loading mechanism. When the gun is cocked, the projectile loading mechanism loads a quantity of the particulate projectiles into the chamber. When the compressed gas release mechanism is activated the projectiles are ejected from the chamber into the barrel and expelled from the gun. The gun optionally includes a laser sighting mechanism. The battery operated laser sighting mechanism is removably attached to the barrel or permanently attached with an integral, trigger operated switch. The projectile storage magazine comprises a cylindrical chamber, said cylindrical chamber having first side and second side projectile loading slots, said loading slots extending from an upper edge of said cylindrical chamber to a base of said cylindrical chamber, said chamber having a circular opening at a lower end; said lower end fitted sealably to an upper end of a vertical circular opening through said chamber; a rectangular projectile feeding tray, said feeding tray surrounding said cylindrical chamber and providing additional space for particulate projectiles outside of said cylindrical chamber.
Patent NZ-750498-A (NZ)
Title: Phenylalanine-free protein for the treatment of pku
Inventor: HOFFMANN BERNHARD
IPC: C07K14/32
Filed: 2017-08-30
Abstract: Provided is a Bacillus subtilis-derived recombinant dietary protein that is free of phenylalanine and has a high biological value. Specifically, B. subtilis general stress protein 16O is modified with a F132W substitution. Further provided are a vector encoding said dietary protein, microorganisms expressing said protein, a method for the production of said protein, and a dietary composition comprising said protein that in an embodiment is for use as a medicament and/or food for special medical purposes in patients with accumulations of phenylalanine (HPA, hyperphenylalaninemia) in the body, and associated disorders (e.g. PKU, phenylketonuria).
Patent NZ-759987-A (NZ)
Title: Network bridge for local transaction authorization
Inventor: ORROCK ANDREW
IPC: G06Q20/20
Filed: 2016-11-14
Abstract: Stored value card transactions typically require a retailer point-of-sales (POS) terminal, system, or host to communicate with a remote processor or server to obtain authorization and conduct the transaction. However, in certain circumstances, communication with the remote processor may not be possible or timely. This may be due to power or network outages, and peak hours or network overloads. The present invention provides an apparatus and the means for locally processing stored value card transactions, with the apparatus proximate to a retailer POS or host. This enables selective communication with the POS or host, a stored value card processor interface, enabling selective communication with the stored value card processor and a processing module, enabling selective decision making for certain stored value card transaction requests.
Patent PT-108598-A (PT)
Title: Película comestível retardadora da acção microbiana em bombons de chocolate com recheio.
Inventor: ANTÓNIO JOÃO PEIXEIRO MELGÃO
IPC: A23G1/00
Filed: 2015-06-29
Abstract: A PRESENTE INVENÇÃO DIZ REPEITO A UMA PELÍCULA COMESTÍVEL RETARDADORA DA ACÇÃO MICROBIANA EM BOMBONS DE CHOCOLATE COM RECHEIO QUE COMPREENDE EM PERCENTAGEM EM PESO DOS COMPONENTES RELATIVAMENTE AO PESO TOTAL DA COMPOSIÇÃO, A) 80 E 95% DE UMA SOLUÇÃO DE QUITOSANO; B) 7 E 9% DE MANTEIGA DE CACAU; C) 0,9 E 1,1% DE LECITINA DE SOJA; E D) 0,9 E 1,1% DE GLICERINA. ESTA PELÍCULA COMESTÍVEL SERÁ UTILIZADA NA CAMADA INTERNA DO CHOCOLATE, ENTRE O RECHEIO E A CONCHA DO BOMBOM, QUE ATUARÃO COMO BARREIRA, PRESERVANDO E MANTENDO A TEXTURA E O SABOR DO RECHEIO E PROTEGENDO-O DA DEGRADAÇÃO MICROBIANA NOMEADAMENTE BOLORES, DADO O CARÁCTER ANTI-FÚNGICO DO QUITOSANO.
Patent PT-109338-A (PT)
Title: Chuveiro de mão para baixo caudal
Inventor: JOSÉ CARLOS A SOARES
IPC: B05B1/30
Filed: 2016-04-20
Abstract: O PRESENTE INVENTO REFERE-SE A UM CHUVEIRO DE ELEVADO DIÂMETRO PARA SER UTILIZADO COM BAIXO CAUDAL. O INVENTO PODE OU NÃO SER CONCRETIZADO COM ESCOVAS FLEXÍVEIS, SEMIFLEXÍVEIS OU RÍGIDAS. ESTE INVENTO, OFERECE AO UTENTE A CAPACIDADE DE PODER USUFRUIR A TOMA DO DUCHE COM UM BAIXO CAUDAL. NOS MODELOS COM ESCOVAS, O INVENTO OFERECE AO SEU UTENTE A POSSIBILIDADE DE EFETUAR UMA CONFORTÁVEL E REVIGORANTE MASSAGEM E/OU ESCOVAGEM CORPORAL.