baber/WOPTO huggingface dataset:
Patent CA-3043203-A1 (CA)
Title: Indazole derivatives useful as inhibitors of diacylglyceride o-acyltransferase 2
Inventor: SHEN DONG-MING
IPC: A61K31/381
Filed: 2017-11-13
Abstract: The present invention relates to a compound represented by formula I': and pharmaceutically acceptable salts thereof. The compounds of formula I are inhibitors of diacylglyceride O-acyltransferase 2 ("DGAT2") and may be useful in the treatment, prevention and suppression of diseases mediated by DGAT2. The compounds of the present invention may be useful in the treatment of hepatic steatosis, diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cardiorenal diseases such as chronic kidney diseases and heart failure and related diseases and conditions.
Patent CA-3047103-A1 (CA)
Title: Installation de boulon et systeme de tension
Inventor: SHAW STEVEN W
IPC: B25B29/02
Filed: 2017-12-13
Abstract: Selon la présente invention, un système d'installation et de retrait de boulon est utilisé pour assembler et désassembler une cuve nucléaire. Le système BIR comprend une plate-forme (210) ayant un support permettant de soutenir la cuve nucléaire. Une piste (204) s'étend autour d'un périmètre extérieur de la plate-forme et de multiples chariots à outils (202) comprennent des roues (208) qui roulent sur la piste. Des tours d'outil (212) sont situées sur les chariots et comprennent des ensembles d'outils (214) configurés pour installer et retirer des boulons (220) sur la cuve de réacteur nucléaire. Des tours de magasin (216) s'étendent également à partir des chariots d'outils à côté des tours d'outils et comprennent des magasins (218) qui maintiennent des boulons permettant d'échanger avec les ensembles d'outils. Des mécanismes d'entraînement (238) déplacent des têtes d'outil dans les ensembles d'outils autour d'un premier axe vertical, verticalement vers le haut et vers le bas, et latéralement pour installer et retirer de manière plus simple et plus fiable les boulons dans un environnement sous-marin radioactif.
Patent CA-3049582-A1 (CA)
Inventor: SCHOBEL SETH A
IPC: G16H50/20
Filed: 2018-01-05
Abstract: Described herein are systems and methods for determining if a subject has an increased risk of having or developing bacteremia or symptoms associated with bacteremia. Also described are systems and methods for predicting a bacteremia outcome for a subject, systems and methods for generating a model for predicting a bacteremia outcome in a subject, systems and method for determining a subject's risk profile for bacteremia, method of determining that a subject has an increased risk of developing bacteremia, and methods of treating a subject determined to have an elevated risk of developing bacteremia, methods of detecting panels of biomarkers in a subject, and methods of assessing risk factors in a subject having an injury, as well as related devices and kits.
Patent CA-3057741-A1 (CA)
Title: Novel crystal forms of a pol1 inhibitor
Inventor: HADDACH MUSTAPHA
IPC: A61K31/551
Filed: 2018-03-28
Abstract: The present invention relates to novel solid crystalline form of N-methyl-2-(4-methyl-1,4-diazepan-1-yl)benzo[4,5]imidazo[1,2-a][1,8]naphthyridine-6-carbaxomide, processes for the preparation thereof, compositions thereof and method of use thereof.
Patent CA-3059056-A1 (CA)
Inventor: CHISTOV SERGEY Y
IPC: A61K9/00
Filed: 2018-05-07
Abstract: A dosage delivery film composition containing a botanical drug substance formable into a bioerodible dosage delivery film, the dosage delivery film composition including: (i) one or more of: a polymer, a plasticizer, a defoamer, or an antioxidant; (ii) a cannabinoid-cyclodextrin- terpene complex or a cannabinoid-terpene-surfactant micelle, and (iii) optionally, one or more of: a taste mask, a vasodilator, or a lipophilic vehicle to transport the botanical drug substance across the mucous membrane.
Patent CA-3062290-A1 (CA)
Inventor: REINERT MICHAEL J
IPC: E02F3/96
Filed: 2018-04-27
Abstract: An adjustable coupler includes a frame, a first bracket, and a second bracket. One or both of the first bracket and the second bracket are slidably combined with the frame along a slot formed in the frame. A fastener extends from each bracket and is received into the slot allowing the bracket to slide along the frame. The fastener also serves to securely fasten the bracket to the frame after it is moved to its desired position. The slidable engagement of the brackets with the frame allows the distance between the brackets to be selectively changed allowing them to be secured to different types and sizes of mobile attachment devices. The frame further includes an attachment opening adapted to receive a pin for connecting a motor or prime mover vehicle with the adjustable coupler.
Patent CA-3062306-A1 (CA)
Title: Overhead sidelight
Inventor: RITONIEMI JARI
IPC: H05B44/00
Filed: 2019-11-20
Abstract: The invention relates to a method for illuminating a wood fibre web for deviation detection. The method comprises turning on LEDs of an overhead sidelight that are side-directed towards a first edge of the web for illuminating a first half of width of the web, capturing an image of the first half, turning off the LEDs, turning on LEDs of the overhead sidelight that are side-directed towards a second edge of the web for illuminating a second half of width of the web, capturing an image of the second half, and turning off the LEDs. The invention also relates to an overhead sidelight, a machine vision system, and a lighting system.
Patent CA-3065667-A1 (CA)
Inventor: JANSSENS TON V W
IPC: C07B41/00
Filed: 2018-06-07
Abstract: In a process for the oxidation of a lower alkene, such as ethylene, over a catalyst containing Cu and one or more zeolite or zeotype materials, the oxidation is conducted in the presence of ammonia in the feed gas at a process temperature below 350°C. The oxidation can be performed in a continuous process.
Patent CA-3068533-A1 (CA)
Inventor: BACA ADRA
IPC: G02B6/38
Filed: 2018-06-22
Abstract: La présente invention concerne des connecteurs de fibres optiques, des boîtiers de connecteurs, des ensembles de câbles connectorisés, et des procédés pour la connectorisation d'ensembles de câbles, qui comprennent des éléments adaptateurs de câbles particuliers, des rallonges d'adaptateurs, des flexions d'étanchéité à plusieurs diamètres, des organes d'étanchéité sous-cutanés, et des combinaisons de ceux-ci, pour des performances, une intégrité et une longévité de connecteurs et de câbles améliorées.
Patent CA-3069547-A1 (CA)
Inventor: HEUFT BERNHARD
IPC: G01N21/93
Filed: 2018-09-06
Abstract: L'invention concerne un dispositif d'inspection de contenants pour rechercher des impuretés, ce dispositif présentant une source de rayonnement. La source de rayonnement est conçue pour émettre un rayonnement qui traverse un contenant à examiner. Le dispositif présente en outre un système de détection qui est conçu pour détecter le rayonnement qui a été émis par la source de rayonnement et qui a traversé le contenant. Le dispositif selon l'invention présente par ailleurs un système d'évaluation qui est conçu pour évaluer le rayonnement détecté par le système de détection. Un élément d'identification qui présente un filigrane optique est disposé sur le chemin optique entre la source de rayonnement et le système de détection.
Patent CA-3071451-A1 (CA)
Inventor: KOVACS ANDRAS
IPC: H01M10/054
Filed: 2018-08-02
Abstract: Components and structures for a rechargeable electrochemical cell and an electrochemical cell having an S02 solvent based electrolyte comprising any of said components and structures are provided. The cathode (2) may comprise one or more elemental transition metals and/or one or more partially oxidized transition metals. The S02 solvent based electrolyte (3) may comprise halide- containing salt additive as an SEI-forming additive. The anode current collector (5) may comprise a carbon coated metal, an alloy of two or more metals or a carbon coated alloy of two or more metals. The electrochemical cell may comprise excess non-dissolved/solid alkali halides. The components, structures and cell may bay used in a device.
Patent CA-3072203-A1 (CA)
Inventor: LUMBATIS KURT ALAN
IPC: H04W28/08
Filed: 2018-08-24
Abstract: L'invention concerne des procédés, des systèmes et des supports lisibles par ordinateur qui peuvent être utilisés pour faciliter l'orientation de station sur la base d'un impact de canal calculé. Un impact de canal de déplacement d'une station vers un ou plusieurs points de liaison différents à l'intérieur d'un WLAN peut être calculé et, en se basant sur les impacts de canal calculés, la station peut être orientée vers un certain point de liaison. Les impacts de canal calculés peuvent être utilisés pour sélectionner une ou plusieurs stations en vue d'être retirées d'un point de liaison surchargé, un nouveau point de liaison peut être sélectionné pour une association avec une station et une détermination peut être effectuée afin de décider si d'autres changements de WLAN peuvent amener l'utilisation d'un canal d'amenée ou frontal à dépasser un seuil correspondant.
Patent CA-3074052-A1 (CA)
Inventor: HUTCHINSON JAMES ALEXANDER
IPC: C12Q1/68
Filed: 2018-08-28
Abstract: The present invention relates to a method for detecting regulatory T cells (Tregs) in the blood of a subject by use of a novel marker. The method includes the detection of at least one commonly known marker for regulatory T cells (Tregs) in combination with the detection of the marker BTNL8. The method allows the reliable detection and quantification of different Treg populations which are involved in important immunological functions, such as immunosuppression and maintenance of immune tolerance. The invention also provides a method for monitoring the treatment of a subject suffering from an immunological disease or condition which makes use of the novel marker. The invention also relates to the use of a means that allow the specific detection of BTNL8 for detecting Tregs. Kits comprising detection means for detecting commonly known markers of Tregs along with BTNL8 are also provided.
Patent CA-3074185-A1 (CA)
Inventor: TAKESHITA SHOTA
IPC: D06M15/277
Filed: 2018-10-04
Abstract: Provided is a fiber structure having high adhesion suppressibility against aqueous soil and oily soil and soil removability in washing. A soil resistant fiber structure includes a resin film on at least a part of a fiber surface, the resin film containing polyvinyl alcohol and a fluorine-based oil-repellent resin having a hydrophilic component, the fiber structure having a water repellency degree of 2 or less as measured by a spray test in accordance with JIS L-1092, and an oil repellency degree of 2 or more as measured in accordance with AATCC 118 method.  The fluorine-based oil-repellent resin is preferably a fluorine-based oil-repellent resin containing a polyoxyalkylene group. The polyvinyl alcohol preferably has an average polymerization degree of 200 to 1500.
Patent CA-3076853-A1 (CA)
Inventor: ROGAN ANDREW ROBERT JOHN
IPC: A24F40/42
Filed: 2018-09-24
Abstract: L'invention concerne une cartouche consommable destinée à un dispositif de génération d'aérosol. La cartouche (10) contient un matériau de formation d'aérosol (14) tel que du tabac, qui peut libérer de la vapeur lors de la réception de chaleur à partir d'un appareil de chauffage. La cartouche (10) comprend un boîtier (12) muni d'une languette (24) qui se déplace entre une position ouverte et une position fermée, la position ouverte s'étendant à partir du boîtier (12) en vue de permettre un refroidissement rapide de la languette, de sorte que l'utilisateur puisse facilement saisir la languette (24) et extraire la cartouche (10) du dispositif de génération d'aérosol.
Patent CA-3077301-A1 (CA)
Title: Methods for performing tasks in a tank containing hazardous substances
Inventor: MEYERS JOHN W
IPC: G01N29/26
Filed: 2017-12-15
Abstract: A method of performing a selected task in a tank containing an energetic substance uses an inherently safe mobile platform that includes a marker detector, a control unit, a power supply, a propulsion system, and an inherently safe enclosure. The inherently safe enclosure prevents a spark occurring inside the inherently safe enclosure from passing to an exterior of the inherently safe enclosure. All spark-generating components of the mobile platform are positioned inside the inherently safe enclosure. The method includes lowering the mobile platform into the tank, at least partially submerging the mobile platform in the energetic substance, and detecting a marker using the marker detector. No active physical carrier connects the mobile platform to an object exterior of the tank while the mobile platform is in the tank.
Patent CA-3078496-A1 (CA)
Inventor: SILVERMAN JAMES D
IPC: A61F2/07
Filed: 2018-10-09
Abstract: Divers aspects de la présente invention concernent des dispositifs médicaux implantables qui comprennent un cadre et un élément tubulaire fixé au cadre. L'élément tubulaire comprend une ou plusieurs fibrilles ou une résistance en alignement avec une ou plusieurs entretoises du cadre.
Patent CA-3078790-A1 (CA)
Title: Threaded connection for pipe and method for producing threaded connection for pipe
Inventor: OSHIMA MASAHIRO
IPC: F16L15/00
Filed: 2018-10-12
Abstract: Provided is a threaded joint for pipes, which has achieved excellent welding resistance without performing a surface roughening step, said excellent welding resistance being comparable to those in cases where a surface roughening step is performed, and which has low shouldering torque. A threaded joint (50) for pipes according to the present invention is provided with a pin (13) and a box (14). This threaded joint for pipes is provided with a Zn-Ni alloy plating layer (21) and a solid lubricating coating film (23). The Zn-Ni alloy plating layer (21) is formed on a contact surface of at least one of the pin (13) and the box (14), and contains 10-16% by mass of Ni. The solid lubricating coating film (23) is formed on the Zn-Ni alloy plating layer (21). The contact surface, on which the Zn-Ni alloy plating layer (21) is formed, has been ground. If Ra1 is the arithmetic mean roughness of the surface of the Zn-Ni alloy plating layer (21) and Ra2 is the arithmetic mean roughness of the contact surface, Ra1 is 0.1-3.2 µm, and Ra1 is larger than Ra2.
Patent CA-3079402-A1 (CA)
Inventor: LI ZHEN
IPC: C07D413/12
Filed: 2018-10-31
Abstract: Synthetic a?ß6 integrin ligands of Formula I having serum stability and affinity for integrin a?ß6, which is a receptor expressed in a variety of cell types, are described. The described ligands are usful for delivering cargo molecules, such as RNAi agents or other oligonucleotide- based compounds, to cells that express integrin a?ß6, and thereby facilitating the uptake of the cargo molecules into these cells. Compositions that include a?ß6 integrin ligands and methods of use are also described.
Patent CA-3081967-A1 (CA)
Title: Method and system for connected advanced flare analytics
Inventor: Gurajapu Prasanna Murthy
IPC: F23G5/50
Filed: 2020-06-04
Abstract: A method and system for advanced flare analytics in a flare operation monitoring and control system is disclosed that contains a data acquisition and augmentation mechanism whereby data is aquired through a plant network including images of the flare operations from single or multi-camera hubs. A machine learning-based self- adaptive industrial automation system process the images and data and assigns pixels to the images according to categories selected from smoke, flame and steam. The results of the analysis are displayed and a notice is issued when the percentage of pixles in a specific category falls outside a predeterminmed range.
Patent CA-3082472-A1 (CA)
Inventor: FILIPPOV ANDREY
IPC: G06N3/08
Filed: 2017-12-26
Abstract: System and methods for training neural network models for real-time flow simulations are provided. Input data is acquired. The input data includes values for a plurality of input parameters associated with a multiphase fluid flow. The multiphase fluid flow is simulated using a complex fluid dynamics (CFD) model, based on the acquired input data. The CFD model represents a three-dimensional (3D) domain for the simulation. An area of interest is selected within the 3D domain represented by the CFD model. A two-dimensional (2D) mesh of the selected area of interest is generated. The 2D mesh represents results of the simulation for the selected area of interest. A neural network is then trained based on the simulation results represented by the generated 2D mesh.
Patent CA-3082728-A1 (CA)
Inventor: GREGORY WALTER MARTIN
IPC: C12Q1/6886
Filed: 2018-11-21
Abstract: La présente invention concerne la conception d'une thérapie personnalisée destinée à un sujet atteint de cancer du sein sur la base du niveau d'expression de c-MAF et de l'état de ménopause du sujet. Dans certains modes de réalisation, la thérapie personnalisée comprend un agent permettant d'éviter, de traiter ou de prévenir la dégradation osseuse. Dans certains modes de réalisation, l'agent destiné à éviter, à traiter ou à prévenir la dégradation osseuse est l'acide zolédronique.
Patent CA-3083864-A1 (CA)
Inventor: NAKANO TOKUSHIGE
IPC: C12N5/079
Filed: 2018-11-22
Abstract: The present invention aims to provide a method for efficiently producing a cell mass containing pituitary tissue from pluripotent stem cells. A method for producing a cell mass containing pituitary tissue, including the following steps (1) and (2): (1) a first step of suspension-culturing pluripotent stem cells to form a cell aggregate in the presence of a Wnt signal transduction pathway inhibiting substance, (2) a second step of suspension-culturing the aggregate obtained in the first step in the presence of a BMP signal transduction pathway activating substance and a Sonic hedgehog signal transduction pathway activating substance, thereby obtaining a cell mass comprising pituitary tissue.
Patent CA-3085355-A1 (CA)
Inventor: REBELLA GREG
IPC: A61B1/00
Filed: 2018-12-21
Abstract: Un otoscope comprend un affichage circulaire permettant à un boîtier compact d'assurer une visualisation simultanée améliorée de l'affichage et de l'oreille du patient pour un positionnement et une stabilisation améliorés de l'otoscope. Une image enregistrée peut être corrigée en rotation, et des données qui ne sont pas des images affichées sur l'écran peuvent être corrigées en rotation à l'aide d'un inclinomètre.
Patent CA-3087995-A1 (CA)
Inventor: CASHMAN JAY
IPC: E02F7/04
Filed: 2018-12-14
Abstract: Described are a vessel and vessel/barge systems for dredging underwater surfaces. The vessel includes a hull with a bottom, bow portion, stern portion, port side, and starboard side. The vessel also includes a deck supported by the hull and a pump system mounted within the hull. A drag arm pivotably couples to the pump system. The vessel additionally includes a void defined by contiguous watertight walls or bulkheads joined to and extending upward from the bottom of the hull. The contiguous watertight walls or bulkheads are (i) vertically extensive of a perimeters of an aperture in the bottom of the hull, (ii) outboard, astern, and forward the aperture, or (iii) some combination thereof. The barge is releasably coupled to the vessel. Moreover, the barge is in fluidic communication with the drag arm.
Patent CA-3090564-A1 (CA)
Title: Razor cartridge connection and handle
Inventor: PARMELE JAMES ROBERT
IPC: B26B21/22
Filed: 2020-08-13
Abstract: A connector for a razor handle having first and second arms, each arm comprising a fixed end, a terminal end where the terminal end has a razor cartridge engagement member movable from a capture position to a release position, a first surface and an opposed second surface. An activator having an activation element acts on each arm for moving the arms toward each other into the release position when the activator is activated, and a biasing member that acts on each arm for biasing the arms outwardly into the capture position. The activation element acts on the arms between the fixed end and the terminal end on the first surface of the arms and the biasing member acts on the arms between the fixed end and the terminal end on the second surface of the arms. Also, a handle having the connecter and a method of making the razor handle.
Patent CA-3093661-A1 (CA)
Inventor: HISAYAMA KAZUSHI
IPC: F24F1/12
Filed: 2019-03-28
Abstract: In refrigeration cycle devices having a double vibration isolation structure, it was further problematic that, when trying to perform refrigerant cooling of an electronic component fixed to a casing, due to vibration from the compressor, piping of the refrigerant cooling unit would be subjected to stress due to vibration. A vibration transmission suppressing unit is provided on communication piping that connects a refrigeration cycle component and cooling refrigerant piping of the electronic component.
Patent CA-3093869-A1 (CA)
Title: Extension de confiance dans un cadre de communication securise
Inventor: ROBERT RAPHAEL
IPC: H04W12/00
Filed: 2019-03-14
Abstract: Il est décrit un cadre de communication dans lequel chacun ou chacune d'une pluralité d'utilisateurs ou d'utilisatrices est associé ou associée à au moins un dispositif, et les utilisateurs ou utilisatrices utilisent au moins certains de leurs dispositifs pour communiquer par l'intermédiaire d'un système dorsal. Un premier utilisateur est associé, ou une première utilisatrice est associée, à un premier ensemble d'au moins un premier dispositif de confiance, et un deuxième utilisateur, ou bien une deuxième utilisatrice, est associé ou associée à un deuxième ensemble d'au moins un deuxième dispositif de confiance. Le premier utilisateur, ou la première utilisatrice, forme une première relation de confiance entre un premier dispositif du premier ensemble et un deuxième dispositif du deuxième ensemble. Il est décrit, sur la base de la première relation de confiance, et du deuxième ensemble associé au deuxième utilisateur, ou à la deuxième utilisatrice, ainsi que dudit premier ensemble, la formation d'une deuxième relation de confiance entre chaque dispositif dudit premier ensemble et chaque dispositif dudit deuxième ensemble de sorte qu'au moins un dispositif du premier ensemble communique avec au moins un dispositif du deuxième ensemble.
Patent CA-3097589-A1 (CA)
Inventor: AZRAK FRUET ILMAR
IPC: E21B10/46
Filed: 2019-04-17
Abstract: The present invention relates to a system for monitoring wear of a drill bit, comprising: a drill bit provided with: a cutting surface; an internal matrix; and a channel at an internal region of the drill bit, beneath the cutting surface; a source of pressurised drilling fluid, the internal matrix of the drill bit being connected to the source of pressurised drilling fluid, and configured to receive drilling fluid from the internal matrix; and a monitor for monitoring the pressurised drilling fluid; wherein the channel is configured to release drilling fluid to an exterior of the drill bit when the cutting surface above the internal region is worn away to expose the channel. There is also provided a drill bit and method associated with the system.
Patent CA-3098813-A1 (CA)
Inventor: JAASKELAINEN MIKKO
IPC: E21B47/10
Filed: 2020-11-12
Abstract: A system can calculate estimated strain data for a fracture in a geological formation at each of a plurality of selected locations detectable by a strain measurement device. The system can receive real strain data from the strain measurement device for the geological formation. The system can perform a linear inversion to determine a probable distribution of fluid volume and hydraulic fracture orientation in the geological formation based on the estimated strain data and real strain data. The system can determine adjustments for a fracturing operation based on the linear inversion.