baber/WOPTO huggingface dataset:
Patent AU-2017341736-A1 (AU)
Title: Rationally-designed synthetic peptide shuttle agents for delivering polypeptide cargos from an extracellular space to the cytosol and/or nucleus of a target eukaryotic cell, uses thereof, methods and kits relating to same
Inventor: DEL'GUIDICE THOMAS
IPC: C12N9/22
Filed: 2017-10-11
Abstract: The present description relates to methods for delivering polypeptide cargos from an extracellular space to the cytosol and/or nucleus of a target eukaryotic cell. The methods involve contacting the cell with the polypeptide cargo in the presence of a peptide shuttle agent at a concentration sufficient to increase the polypeptide cargo's transduction efficiency. Also described here are parameters that may be used in the rational design of such synthetic peptide shuttle agents, peptide shuttle agents that satisfy one or more of these design parameters, as well as methods and compositions relating to the use of the synthetic peptide shuttle agents for delivery of a variety of polypeptide cargos (such as transcription factors, antibodies, CRISPR-associated nucleases and functional genome editing complexes) from an extracellular space to the cytosol and/or nucleus of target eukaryotic cells. Applications and targets for genome-editing NK cells for improved immunotherapy are also described.
Patent AU-2017371674-A1 (AU)
Title: Benzenesulfonamide compounds and their use as therapeutic agents
Inventor: ANDREZ JEAN-CHRISTOPHE
IPC: C07D261/16
Filed: 2017-05-19
Abstract: This invention is directed to benzenesulfonamide compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of diseases or conditions associated with voltage-gated sodium channels, such as epilepsy.
Patent AU-2017381803-A1 (AU)
Title: Methods for affecting salmonella infections
Inventor: CORTHÉSY BLAISE
IPC: A61K39/395
Filed: 2017-12-20
Abstract: The invention relates to methods promoting the aggregation of Salmonella bacteria in the gut of subjects, thereby providing immune exclusion and limiting bacterial entry, therefore reducing mucosal and systemic infection.
Patent AU-2017384947-A1 (AU)
Title: Network node and method for configuring PDCP for a wireless device
Inventor: MILDH GUNNAR
IPC: H04W92/20
Filed: 2017-02-08
Abstract: A method performed by a network node for configuring a Packet Data Convergence Protocol (PDCP) for a wireless device in a communications network is provided. The communications network comprises a first type of core network and a second type of core network. The network node decides (801) whether the network node is a master node or a secondary node for the wireless device. When the network node is a master node, it configures (803) the PDCP for the wireless device based on which out of first and second type of core network the wireless device connects to. When the network node is a secondary node, it configures (804) the PDCP for the wireless device (120) based on any one or more out of: Which out of first and second type of master node the network node connects to, and which out of first and second type of core network the wireless device connects to. The first type and the second type relate different generations of telecommunication networks.
Patent AU-2017434032-A1 (AU)
Title: Dispenser
Inventor: MCCACHREN BRIAN C
IPC: A47K10/32
Filed: 2017-09-27
Abstract: A dispenser for dispensing absorbent product having an outer cover having a first cover portion, a second cover portion and an interior region configured to hold the absorbent product and at least partially defined by one or more of the first and second cover portions, wherein the first cover portion is removably engaged to at least a portion of the second cover portion along a cover joint; and wherein the outer cover includes a hydrophobic section proximate the cover joint to direct any liquid on the cover near the cover joint away from the cover joint.
Patent WO-2019079841-A1 (WO)
Inventor: KEMPSON IVAN MARK
IPC: A61N5/10
Filed: 2018-10-26
Abstract: L'invention concerne des procédés de potentialisation d'une chimiothérapie ou d'une radiothérapie.. Les procédés comprennent l'administration à un sujet nécessitant un traitement chimiothérapeutique ou radiothérapeutique d'une quantité efficace d'une composition comprenant des nanoparticules biocompatibles, en particulier des nanoparticules d'or, dans des conditions dans lesquelles les nanoparticules modifient un ou plusieurs mécanismes de régulation cellulaire dans des cellules dans lesquelles les nanoparticules sont situées ou d'autres cellules. Ensuite, une ou plusieurs doses d'un traitement chimiothérapeutique ou radiothérapeutique sont administrées au sujet soit simultanément, soit après que les nanoparticules aient modifié le ou les mécanismes de régulation cellulaire dans les cellules dans lesquelles les nanoparticules sont situées ou d'autres cellules. L'invention concerne également des procédés d'amélioration des effets de la chimiothérapie ou de la radiothérapie sur une population de cellules, des procédés d'augmentation de la quantité de cassures de brins dans l'ADN dans une cellule et des procédés d'induction de la mort des cellules cancéreuses.
Patent AU-2018205117-A1 (AU)
Title: Advanced Dielectric Energy Storage Device and Method of Fabrication
Inventor: FRANK DAVID
IPC: H01G11/12
Filed: 2018-07-11
Abstract: A Dense Energy Ultra Cell (DEUC), a dielectric energy storage device and methods of fabrication therefor are provided. A DEUC element is fabricated using print technologies that deposit dielectric energy storage layers (406) and insulating layers (404) together being interleaved between electrode layers (403). The dielectric energy storage layers are created from a proprietary solution to enable printing of dielectric energy storage layers with high permittivity and a high internal resistivity to retain charge. The insulating layers (404) can be applied within the dielectric energy storage layers (406) bifurcating the dielectric energy storage layers for increased resistivity. As part of the fabrication process, the material deposition printer can apply multiple print heads each with different inks and materials (1301, 1302) to form composite material (1303) in the printed layers. ELECTRODE TOP LAYER DIELECTRIC 402 ENERGY STORAGE 406 eI 4051 405b ELECTRODE 407 ELECTRODE COLLECTOR BOTTOM COLLECTOR DIELECTRIC ENERGY
Patent AU-2018205172-A1 (AU)
Title: Method and apparatus for managing and providing provenance of product using blockchain
Inventor: ALJAWHARI MOHAMED ALAA
IPC: G06K9/00
Filed: 2018-07-12
Abstract: Described is a method for managing and providing provenance of a product using blockchain technology. There is disclosure of the association to the product of a unique product identifier as well as the optional association to the product of an anti-counterfeiting device also having a unique identifier as the product moves along the supply chain from its source phase, through the transformation phase and undergoes the transportation phase. There may be more than one product identifier or anti-counterfeiting device as the product is sometimes joined, sometimes partitioned and sometimes packaged. To manage and facilitate the generation and association of identifiers as the product moves along the supply chain there is a data memory device for storage of the unique identifier for the product and association by the server in the data memory device of the unique identifier for the product with the unique identifier of the anti counterfeit device and other associations. The server is also adapted to receive and store in the data memory device one or more characteristics of the product existing or created as the product moves along the supply chain. Receipt by the processor of the unique identifier of a product or anti-counterfeit device with a query for the provenance of the product, makes available at least one characteristic associated with that product. The use of blockchain permits the creation of a block for each recorded characteristic and the retrieval of the record associated with a block and to verify that the recorded characteristic is the same as that retrieved from the block in the blockchain uniquely associated with the particular product. SOURCE TRANSFORM TRANSPORT Figure 1 SOURCE TRANSFORM TRANSPORT Figure 2
Patent AU-2018207118-A1 (AU)
Title: Method and apparatus for heating and purifying liquids
Inventor: HRINDA RADOVAN
IPC: F22B3/06
Filed: 2018-01-12
Abstract: A fluid cavitation apparatus includes a housing, an external rotor with cavitation bores in an outer surface thereof, and a motor for rotating the external rotor. An inner surface of the housing is spaced from the outer surface of the external rotor to create a fluid cavitation zone. The inner surface of the housing is configured with a spiral shape and tunnel zone to enhance the thermal transfer characterisitics of the fluid for heating, cooling, and purification. A control system to facilitate proper motor speed, and fluid behavior to enhance the cavition process.
Patent AU-2018207893-A1 (AU)
Title: Process for producing a fermented milk product
Inventor: BA ZHAOYONG
IPC: C12N9/38
Filed: 2018-01-12
Abstract: The present invention relates to a process for producing a fermented milk product comprising the steps of 1) adding a starter culture comprising at least one lactic acid bacteria strain to a milk base, 2) fermenting the milk for a period of time until a target pH is reached, 3) using a starter culture comprising at least one lactose-deficient strain, which is capable of metabolizing a non-lactose carbohydrate, and 4) adding a low pH stable lactase to the process either at the start, during or at the end of the fermentation step, wherein the low pH stable lactase retains its activity at a pH of 5.0 and a temperature of 37°C at a level of at least 5% as compared to its activity at the optimum pH of the lactase.
Patent AU-2018214160-A1 (AU)
Title: Novel peptides and analogs for use in the treatment of oral mucositis
Inventor: DONINI OREOLA
IPC: C07K7/00
Filed: 2018-08-13
Abstract: Abstract Preclinical data obtained in models of chemotherapy-induced mucositis, radiation-induced mucositis, neutropenic infection and colitis indicate oral mucositis is a promising indication for Innate Defense Regulator (IDR) peptides. Preclinical efficacy results obtained with IDRs in mouse and hamster models of mucositis indicate that dosing every third day should be able to cover the mucositis "window" with seven to fourteen doses, depending on the duration of chemotherapy or radiation exposure. IDRs have also shown efficacy in mouse models of chemotherapy-induced oral and gastrointestinal mucositis, consistent with the response of the innate immune response to chemotherapy and / or radiation damage. IDRs are also effective at reducing bacterial burden and improve survival in the presence or absence of antibiotic treatment in various murine infection models.
Patent AU-2018226104-A1 (AU)
Title: Portable cooling device for humans and/or animals
Inventor: LABUS HEINRICH RAIMUND
IPC: A61F7/00
Filed: 2018-02-13
Abstract: The invention relates to a portable cooling device for humans and/or animals, in particular a vest, a jacket, a cape, a coat or a blanket, characterized in that the portable cooling device (10) comprises at least two water atomizers, which are connected thereto, together with the reservoirs (2.2, 5), and at least two fans (2.1, 6), in that the portable cooling device (10) has a fixing device so that, when in use, a free ventilation and cooling region (11, 12) is formed between the portable cooling device (10) and the surface to be cooled (13, 14) of the human and/or animal, and in that the fans (2.1, 6) and the water atomizers together with the reservoirs (2.2, 5) for ventilating and cooling said ventilation and cooling region (11, 12) are arranged next to one another.
Patent AU-2018227062-A1 (AU)
Title: Electronically actuated locking differential having lock detection mechanism
Inventor: SURVE RUPESH MADHUKAR
IPC: F16H48/34
Filed: 2018-03-03
Abstract: An electronically locking differential assembly constructed in accordance to the present disclosure includes a differential casing, a first and second side gear, a lock actuation assembly and a lock detect mechanism. The first gear defines a first shaft opening configured to provide a first torque transmitting connection with a first output shaft received within the first output shaft opening. The second side gear defines a second output shaft opening configured to provide a second torque transmitting connection with a second output shaft received within the second output shaft opening. The lock actuation mechanism selectively moves between a locked state where the side gears are fixed for concurrent rotation and an unlocked state where the side gears rotate relative to each other. The lock detect mechanism detects whether the lock actuation mechanism is in the locked or unlocked state.
Patent AU-2018228870-A1 (AU)
Title: Seed firmer
Inventor: MCMAHON BRIAN
IPC: A01C5/06
Filed: 2018-03-01
Abstract: Embodiments of the present disclosure relate to a seed firmer having a resilient portion and a firming portion that are molded together into a unitary part with each portion being a different material.
Patent AU-2018232963-A1 (AU)
Title: Wax-based compositions, articles made therefrom, and methods of manufacture and use
Inventor: JOHNSON STEVEN B
IPC: A61K31/05
Filed: 2018-09-19
Abstract: Wax-based compositions for making barrier layers used in oral treatment devices are thermally stable when formed into a flat sheet or three-dimensional article to a 5 temperature of at least 45'C and are plastically deformable at room temperature (25'C). The wax-based compositions include a wax fraction homogeneously blended with a polymer fraction. The wax fraction includes at least one wax and the polymer fraction includes at least one polymer selected such that, when the at least one wax and at least one polymer are homogeneously blended together, they yield a wax-based composition having 10 the desired properties of thermal stability and plastic deformability. Barrier layers in oral treatment devices made from such wax-based compositions are dimensionally stable to a temperature of at least 40'C without external support and can be plastically deformed in a user's mouth to become at least partially customized to the size and shape of user's unique dentition. 20 10663412_1 (GHMatters) P101002.AU.1
Patent AU-2018247704-A1 (AU)
Title: High performance fibers composite sheet
Inventor: DICKINSON BRAD ALAN
IPC: F41H5/02
Filed: 2018-03-19
Abstract: The invention relates to a composite sheet, and a ballistic resistant article, comprising unidirectionally aligned high performance polyethylene (HPPE) fibers and a polymeric resin, wherein said polymeric resin comprises a homopolymer or copolymer of ethylene and wherein said polymeric resin has a density as measured according to ISO1183 of between 930 and 980 kg/m3, and a peak melting temperature of from 115 to 140°C; and said polymeric resin is present in an amount of from 5 to 25 % by weight based on the total weight of the composite sheet. It further relates to a method for manufacturing a composite sheet comprising assembling HPPE fibers to a sheet, applying an aqueous suspension of a polymeric resin to the HPPE fibers, partially drying the aqueous suspension, optionally applying a temperature and/or a pressure treatment to the composite sheet.
Patent AU-2018263283-A1 (AU)
Title: Personal alarm system
Inventor: LAW JAMES FRANK
IPC: G08B25/01
Filed: 2018-05-01
Abstract: Provided is a distributed personal alarm system (10), which comprises a monitoring arrangement (12) and a plurality of mobile monitors (24). The monitoring arrangement (12) comprises a user database (14), a receiver (16) configured to receive a distress signal via a communications network (200), and a dispatcher (18) configured to dispatch emergency assistance (30) upon receipt of a distress signal. The alarm system (10) generally includes at least one mobile monitor (24) pre-associated with a user profile (26) stored in the user database (14). The monitor (24) is further configured to generate and transmit the distress signal via the communications network (200), wherein the signal is indicative of the user profile (26) and a geospatial position (28) of the mobile monitor (24).
Patent AU-2018269163-A1 (AU)
Title: Device, system and method for monitoring neurological functional status
Inventor: TSAI NANCEY TREVANIAN
IPC: A61B3/00
Filed: 2018-05-15
Abstract: A device for measuring eyelid movement in a human subject comprises a housing, at least one stimulator mounted to the housing, and a camera. The at least one stimulator is configured to provide stimulus to one or both eyes of the subject. The camera is configured to collect information related to movement of one or both eyes of the subject. The device also includes a user interface that is configured to control the at least one stimulator and display information collected by the camera.
Patent AU-2018269941-A1 (AU)
Title: Systems and methods for rapidly building, managing, and sharing machine learning models
Inventor: HUGHES CORY
IPC: G06F17/24
Filed: 2018-05-14
Abstract: In some aspects, systems and methods for rapidly building, managing, and sharing machine learning models are provided. Managing the lifecycle of machine learning models can include: receiving a set of unannotated data; requesting annotations of samples of the unannotated data to produce an annotated set of data; building a machine learning model based on the annotated set of data; deploying the machine learning model to a client system, wherein production annotations are generated; collecting the generated production annotations and generating a new machine learning model incorporating the production annotations; and selecting one of the machine learning model built based on the annotated set of data or the new machine learning model.
Patent AU-2018290469-A1 (AU)
Title: Seat mounted in driving cab, and vehicle
Inventor: LI GONGGUAN
IPC: B60N2/22
Filed: 2018-06-15
Abstract: A seat (100) mounted in a driving cab and a vehicle. The seat (100) comprises a backrest framework (11), a base (20), a recliner assembly (30), side arms (41), a first connecting rod (51), a second connecting rod (52), a third connecting rod (53), and a fourth connecting rod (54). The recliner assembly (30) comprises a first connecting plate (31), a recliner (32), and a second connecting plate (33). The first connecting plate (31) is fixed to the backrest framework (11), and the second connecting plate (33) is selectively fixed to the base (20). The side arms (41) comprise a first side arm (411) and a second side arm (412) that are hingedly connected. The first connecting rod (51) is hingedly connected between the base (20) and the first side arm (411), the second connecting rod (52) is hingedly connected between the second side arm (412) and the third connecting rod (53), and the third connecting rod (53) and the fourth connecting rod (54) are hingedly connected between the second connecting plate (33) and the base (20) respectively. The first connecting rod (51) is located on the front side of the third connecting rod (53), and the fourth connecting rod (54) is located on the front side of the third connecting rod (53). By arranging multiple connecting rods, the seat can be effectively conveyed from a designed use position to a get-on and get-off position of a passenger on a third row, and the height of a seat cushion can be also reduced.
Patent AU-2018295575-A1 (AU)
Title: Improvements in bedding including push-pin securing assembly
Inventor: SAVAGE JANINE
IPC: A47G9/02
Filed: 2018-07-06
Abstract: A system for securing an internal padding element of a doona to conform with the extent of a sheath or cover of the doona; the system including providing fastening means at least proximate the respective four corners of the internal padding element and the sheath or cover of the doona; the fastening means comprising a first component and a second component arranged for releasable coupling one to the other; each first and second component provided with attachment means for securing respective components to the padding element and to the cover of the doona.
Patent AU-2018298885-A1 (AU)
Title: Photosensitive array
Inventor: DETERRE MARTIN
IPC: A61N1/36
Filed: 2018-07-13
Abstract: The present invention relates to photosensitive arrays comprising a plurality of photosensitive elements disposed in or on a suitable substrate. The photosensitive arrays are useful as implants, in particular as retinal implants. Methods for manufacturing such arrays are also provided.
Patent AU-2018346818-A1 (AU)
Title: Expansion and use of expanded NK cell fractions
Inventor: PELED TONY
IPC: C12N5/071
Filed: 2018-09-27
Abstract: Methods of expanding a natural killer (NK) cell fraction for transplantation into a subject are provided, and particularly, methods for providing transplantable NK cell fractions and protocols for their use, which can be employed for applications in cell transplants and infusions for treatment of cancer and other disease.
Patent AU-2018347466-A1 (AU)
Title: Method and system for performing operations using communications
Inventor: ZHANG YIBING
IPC: E21B47/16
Filed: 2018-09-24
Abstract: A method and system are described for communicating within a system, which may be along tubular members. The method includes constructing a communication network for tubular member, such as a wellbore accessing a subsurface region or a pipeline, and using the communication network in hydrocarbon operations, such as hydrocarbon exploration, hydrocarbon development, and/or hydrocarbon production.
Patent AU-2018364870-A1 (AU)
Title: Metal product manufacturing device and metal product manufacturing method
Inventor: TAKAHASHI KENZO
IPC: C22B9/00
Filed: 2018-09-04
Abstract: [Problem] To obtain a more high-purity melt by making it possible to remove impurities with greater precision from a melt comprising impurity-containing non-ferrous metals or metals of other kinds, thereby enabling a high-purity non-ferrous metal product or metal products of other kinds to be obtained from the high-purity melt. [Solution] The present invention is provided with: a cylindrical container body section; an upper endplate and a lower endplate for sealing both ends of the container body section in an airtight manner; an upper electrode affixed, so that an inner end thereof can be electrically connected to the melt, to the upper endplate and penetrating therethrough; and a lower electrode affixed, so that an inner end thereof can be electrically connected to the melt, to the lower endplate and penetrating therethrough. At least the upper endplate is detachably attached to the container body section, the upper electrode is penetratingly affixed substantially at the center of the upper endplate in the thickness direction thereof, the lower electrode is penetratingly affixed substantially at the center of the lower endplate in the thickness direction thereof, and the upper electrode and the lower electrode are disposed on a substantially vertical straight line.
Patent AU-2018367631-A1 (AU)
Title: System and methods for supercooling products
Inventor: BOWDEN R CRAIG
IPC: A23B9/10
Filed: 2018-11-16
Abstract: A system for supercooling a product is provided, the system comprising: a chamber containing a supercooling medium; and disruptors that emit sound waves, ultrasound waves, and/or electromagnetic waves in the chamber; wherein during a cooling cycle the chamber reaches a cooling temperature below 0°C and during a warming cycle the chamber reaches a warming temperature greater than the cooling temperature. The supercooling system may be used to supercool perishable products below freezing to extend shelf life and freshness of the products. Other embodiments of the supercooling system, and methods for its use, are described herein.