baber/WOPTO huggingface dataset:
Patent DE-69302369-D1 (DE)
Inventor: GOODCHILD JOHN
IPC: C07H21/00
Filed: 1993-02-04
Granted: 1996-05-30
Abstract: Methods are disclosed for increasing ribozyme catalytic activity without reducing specificity, which methods comprise contacting an RNA molecule with a ribozyme and a facilitator oligonucleotide. The present invention further provides compositions comprising a ribozyme and an effective amount of a facilitator oligonucleotide. Methods are also disclosed for reducing the concentration of Mg<2+> and Mn<2+> required by a ribozyme to catalytically cleave target RNA.
Patent DE-69305161-D1 (DE)
Inventor: VIALLEVIEILLE ALAIN
IPC: H04H20/67
Filed: 1993-04-21
Granted: 1996-11-07
Abstract: The invention relates to a method for synchronizing at least one analog component of a multiplex signal comprising at least one digital data channel. At the emission, in a channel (IRNS) is inserted at least one additional channel (RDS) comprising digital information, and comprising patterns having a synchronization signal (SYN) allowing to set in phase at least one analog component as well as said digital information. At the reception, the synchronization signal (SYN) is detected and allows to synchronize said analog component and the digital information of the additional channel. The synchronization at the reception may comprise a step for generating a signal with a characteristic frequency from a wave form generator (WG).
Patent DE-69308777-D1 (DE)
Inventor: MAHONEY ROBERT P
IPC: C01F7/145
Filed: 1993-12-09
Granted: 1997-04-17
Abstract: In a Bayer process for the production of alumina, the crystal formation of alumina trihydrate is improved by adding to the clarified sodium aluminate liquor an anionic water-soluble hydroxamated polymer in an amount effective to provide an upward shift in the particle size distribution and alumina trihydrate crystals formed upon precipitation from the feed liquor.
Patent DE-69333678-D1 (DE)
Inventor: HANSEN MICHAEL R
IPC: D06M13/256
Filed: 1993-08-16
Granted: 2004-11-25
Abstract: This invention concerns polymeric and non-polymeric binders for fibers and the use of such binders in binding particles to fibers.
Patent DE-69403812-D1 (DE)
Inventor: JORGENSEN LARS
IPC: G01N23/06
Filed: 1994-10-05
Granted: 1997-07-17
Abstract: An apparatus for measuring the amount of earth on agricultural crops, such as beets, on the basis of an absorption measurement of  gamma -rays of different energies. The apparatus utilizes that high-energy radiation is absorbed to an equal extent by earth and beets, whereas low-energy radiation is most absorbed by earth, minerals, and stones and less absorbed by organic material and water. The apparatus comprises two probes in form of tubes (1, 2) which can be inserted in a layer of beets, one probe comprising  gamma -radiation sources and the other probe comprising detectors. In this manner a fast and accurate measurement of the earth content in a cartload of beets is rendered possible.
Patent DE-69405001-D1 (DE)
Inventor: DUNMEAD STEPHEN
IPC: C01B32/949
Filed: 1994-05-26
Granted: 1997-09-18
Abstract: A method for making submicrometer metallic carbides and submicrometer solid solution metallic carbides from sources of at least one metallic oxide and carbon involves the rapid heating of a reactive particulate mixture of at least one metallic oxide and carbon in order to achieve a resulting particulate size of less than 1 micrometer. Submicrometer sized metallic carbides and solid solution metallic carbides have found great use in commercial ceramic applications. It has been found that the smaller sized particles produce a product having superior toughness and hardness. In addition, the submicrometer sized solid solution metallic carbide resulting from this method is also disclosed.
Patent DE-69406363-D1 (DE)
Inventor: NEBOLON JOSEPH F
IPC: A61F5/01
Filed: 1994-07-05
Granted: 1997-11-27
Abstract: A hinge assembly is provided for an orthopaedic brace having a rotatable hinge and a detent mechanism to automatically, yet releasably, lock the hinge in a fixed position or rotation. The hinge includes two rotatably attached members and the detent mechanism includes an indentation formed in the attached end of one member and a block pivotally mounted on the other member. The block has a locking projection that is biased toward the indentation and cooperates therewith to provide three positions of operation, a locked position, a release position, and an activated position. In the locked position, the locking projection fittingly engages the indentation, thereby substantially preventing rotation of the hinge. The release position displaces the locking projection a radial distance away from the indentation, thereby permitting the hinge to rotate freely. In the activated position, the block disengages the indentation and maintain an angular distance therefrom so that the detent mechanism does not obstruct rotation of the hinge, but enables automatic repositioning of the hinge assembly to the locked position whenever the locking projection and indentation angularly realign. <IMAGE>
Patent DE-69411160-D1 (DE)
Inventor: HOLSTENSSON LARS
IPC: A47C7/54
Filed: 1994-04-14
Granted: 1998-07-23
Abstract: PCT No. PCT/SE94/00329 Sec. 371 Date Jan. 16, 1996 Sec. 102(e) Date Jan. 16, 1996 PCT Filed Apr. 14, 1994 PCT Pub. No. WO94/23616 PCT Pub. Date Oct. 27, 1994An armrest device for an office chair comprises a fastening element (6) intended to be fixed to the chair beside the seat (4). The-device further includes an armrest (7, 8, 9, 20) which is connected to the fastening element (6) and has a vertical column (7) so connected to the fastening element as to be rotatable about its longitudinal axis, a horizontal rear supporting bar (8) connected to the column, and a front supporting bar (9) carrying a forearm rest (20), on which the user's forearm is to rest, and being telescopically displaceable in relation to the rear supporting bar (8) in order to form an armrest that can be lengthened and shortened as desired. The rear supporting bar (8) is so mounted on the column (7) as to be pivotable about a horizontal transverse axis (10). A spring means (15, 16, 17, 18, 19) is arranged to maintain the rear supporting bar (8) in an initial position and to counteract, with an adjustable spring pressure, pivotal movement of the rear supporting bar (8) about the horizontal transverse axis (10) caused by a depression of The forearm rest (20).
Patent DE-69424794-D1 (DE)
Inventor: DYBAS MICHAEL
IPC: A61K31/7036
Filed: 1994-09-23
Granted: 2000-07-06
Abstract: The present invention relates to oligosaccharide-containing 14-aminosteroid compounds and the pharmaceutically-acceptable acid salts or esters thereof of the general formula: <CHEM>  wherein     a) R1 is     (i) COOR5, where R5 is hydrogen, a 1-6 carbon lower alkyl ; a 1-6 carbon lower alkyl substituted by an amino group; an arylalkyl or heteroarylalkyl or a carbocyclic ring, or   (ii) CHR6OH, where     R6 is a hydrogen atom or 1-6 carbon lower alkyl group, or (iii) COR''', where R''' is hydrogen; 1-6 carbon lower alkyl; 1-6 carbon lower alkyl substituted amino; amino or dialkylamino; and     b) R2 is -NR7R8, where R7 and R8, which may be the same or different, are hydrogen atoms or a 1-6 carbon lower alkyl ; and   c) R3 is   (i) an oligosaccharide sugar residue having the following structure:   <CHEM> where R9 is hydrogen; methyl; hydroxy; carboxy; acetoxy; arylalkyloxy; heteroarylalkyloxy or benzoxy; R10 is hydrogen; methyl; carboxy; acetoxy; arylalkyloxy; heteroarylalkyloxy; benzoxy or hydroxy; R11 is oxygen; wherein further when R11 is a substituent on the terminal monosaccharide sugar residue; R11 is OH; methyl; acetoxy; arylalkyloxy; heteroarylalkyloxy; and R12 is a hydrogen; methyl; methylhydroxymethyl; or acetoxymethyl; or (ii) an oligosaccharide sugar residue having the following structure:   <CHEM> where R14 and R15, which may be the same or different, are hydrogen; 1-6 carbon lower alkyl; heteroarylalkyl; arylalkyl; heteroaryl or aryl; R17 can be hydrogen; hydroxy; acetoxy or benzoxy; R18 and R19 are hydroxy; acetoxy and benzoxy; or   (iii) an oligosaccharide residue having the following structure: <CHEM> where R14 and R15, which may be the same or different, are hydrogen; 1-6 carbon lower alkyl; heteroaryl alkyl; arylalkyl; heteroaryl or aryl; R14a is oxygen; wherein further when R14a is a substituent on the terminal monosaccharide sugar residue; R14a must be hydroxy; methyl; acetoxy; arylalkyloxy or heteroarylalkyloxy; and     d) R4 is     (i) OH, or   (ii) H, or (iii) OR13, where R13 is a monosaccharide sugar residue; acetoxy; benzoxy; arylalkyl or heteroarylalkyl; and     e) Z is     (i) -CH-, where a and b are single bonds, or   (ii) =C, where either a or b is a double bond.     The present invention also relates to a process for introducing an amino group at the 14-position on a steroid nucleus wherein said amino group is diasteroselectively introduced onto the 14-position of the steroid nucleus via an iodoisocyanate addition comprising the steps of:   a) adding the iodoisocyanate to the 14-15 position double bond on the steroid nucleus; and   b) dehalogenation; and c) isocyanate conversion to the amine moiety on the 14-position of the steroid nucleus.
Patent DE-69429431-D1 (DE)
Inventor: HARRIS ALAN
IPC: A61K38/095
Filed: 1994-06-22
Granted: 2002-01-24
Abstract: Disclosed is a stabilized aqueous composition for administration to a patient comprising a biologically active peptide, a buffer, a quaternary amine-type preservative or disinfectant, and an osmotic pressure-controlling agent, which composition can be stored and used at room temperature. The buffer stabilizes the pH of the composition between about 4 and 6. The preferred buffer contains citrate and/or phosphate, and the preferred preservative or disinfectant is benzalkonium chloride. The composition protects the peptide contained therein from adhering to container surfaces, particularly in containers made of polymeric materials.
Patent DE-69430673-D1 (DE)
Inventor: ZIMMERMAN MOORE
IPC: G02F1/1335
Filed: 1994-10-18
Granted: 2002-06-27
Abstract: An improved backlight assembly comprising an array of apertures in close proximity to a light source, an array of tapered optical elements that have a light input surface area smaller than the light output surface area. Light rays pass through the apertures and are directed to the optical elements which transmit the light rays via internal reflection to provide a partially collimated light source. The light rays then pass through an array of microlenses that transmit the light rays via refraction and provide a substantially more collimated light source for the display elements of a display. The backlight assembly is advantageously used as a backlighting means for electro-optical displays, especially those designed for military and avionics applications.
Patent DE-69430695-D1 (DE)
Inventor: SKOLNICK PHIL
IPC: A61P25/28
Filed: 1994-01-07
Granted: 2002-07-04
Abstract: The use of a compound possessing functional antagonist properties at the NMDA receptor complex through a specific action at the associated strychnine-insensitive glycine site to improve cognition in normal humans and to treat cognitive deficits resulting from chronic neuronal degeneration, acute brain injury, hypoxia, or other neurological disorders is provided. The compounds possessing functional antagonist properties comprise 1-aminocyclopropanecarboxylic acid, and its pharmaceutically acceptable esters, salts, and acid addition salts or 7-chlorokynurenic acid, and its pharmaceutically acceptable esters, amides, salts, ethers, and acid addition salts.
Patent DE-69433552-D1 (DE)
Inventor: BECKMANN M PATRICIA
IPC: A61K38/00
Filed: 1994-08-17
Granted: 2004-03-18
Abstract: Hek ligand (hek-L) polypeptides as well as DNA sequences, vectors and transformed host cells useful in providing hek-L polypeptides. The hek-L polypeptides bind to a cell surface receptor (hek) that is a member of the receptor tyrosine kinase family. Hek is expressed on cells that include certain tumor cell lines. The hek-L polypeptides also bind a distinct receptor tyrosine kinase known elk.
Patent DE-69501550-D1 (DE)
Inventor: NASSR DJAFAR
IPC: H02P23/24
Filed: 1995-09-29
Granted: 1998-03-05
Abstract: The control unit (14) is designed to stop operation of the motor (2) when an overload exceeds a set value. The unit (14) includes a device (8) for measuring phase shift between one of several parameters: voltage or current (U1,U2,I2,I3) of the principal phase (1) and/or the auxiliary phase (2) and another of these parameters. The unit (14) interrupts the supply to the motor (2) when the measured delay time is less than a set value contained in memory (13).
Patent DE-69501785-D1 (DE)
Inventor: GOSSET SERGE
IPC: B01D17/05
Filed: 1995-06-06
Granted: 1998-04-16
Abstract: Method of breaking an emulsion, especially an oil-in-water emulsion, using at least one cyclodextrin. Advantageously, said cyclodextrin can be selected from alpha-cyclodextrin, beta-cyclodextrin and their derivatives. The stable emulsion to be treated generally contains an anionic, cationic, amphoteric or non-ionic surfactant, and in particular an oil-in-water emulsifying agent. The emulsion to be broken can already contain a cyclodextrin, a substance known for forming or stabilizing all kinds of emulsions of different formulations. This method of treating an emulsion recovers fats from initial emulsions, and from complexes as well, with a view to recycling or commercialisation.
Patent DE-69502451-D1 (DE)
Inventor: BERTINA ROGIER MARIA
IPC: C12Q1/6883
Filed: 1995-02-14
Granted: 1998-06-18
Abstract: Method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C (APC). The method is directed at detecting one or more mutations at one or more of the cleavage and/or binding sites for APC of Factor V and/or Factor Va or at Factor VIII and/or Factor VIIIa at either nucleic acid or protein level or both.
Patent DE-69502879-D1 (DE)
Inventor: ESPINOZA THERESE A
IPC: C04B28/14
Filed: 1995-02-06
Granted: 1998-07-16
Abstract: A comentitious composition of the setting type which can be kept in a ready-mixed state and which can be caused to set and harden upon introduction of an accelerator with reproducibility and set time predictability. The cementitious base composition contains calcium sulfate hemihydrate as a principal filler material and certain non-calciun bearing phosphate additives which prevent setting action in the presence of water. An accelerator, such as zinc sulfate, may be added to the ready-mixed, cementitious composition to initiate the setting action, or the ready-mixed cementitious composition can be used as a drying type joint compound without the addition of an accelerator.
Patent DE-69506105-D1 (DE)
Inventor: GRIGOROVA BOJIDARA
IPC: B01D53/94
Filed: 1995-06-19
Granted: 1998-12-24
Abstract: A catalyst for use in an oxidation reaction comprises a porous alumina support in the form of pellets or powder, preferably powder. The porous alumina support has captured thereon a complex comprising gold, a transition metal selected from cobalt or manganese, and alumina, the concentration of gold on the support being less than 2 percent by mass of the catalyst, and the atomic ratio of gold to transition metal being in the range 1:10 to 1:200.
Patent DE-69508667-D1 (DE)
Inventor: CORDI ALEX
IPC: C07B53/00
Filed: 1995-07-12
Granted: 1999-05-06
Abstract: (3aS)-5,5-Dioxo- 2,3,3a,4-tetrahydro- 1H-pyrrolo (2,1-c) (1,2,4) benzothiadiazine of formula (I) and its salts are new.
Patent DE-69516358-D1 (DE)
Inventor: SKJAEVELAND MAGNE
IPC: A01B17/00
Filed: 1995-05-24
Granted: 2000-05-25
Abstract: PCT No. PCT/GB95/01188 Sec. 371 Date Jan. 16, 1996 Sec. 102(e) Date Jan. 16, 1996 PCT Filed May 24, 1995 PCT Pub. No. WO95/34195 PCT Pub. Date Dec. 21, 1995An integrated combination of a reversible plow and a soil preparation device which includes a headstock, a carrying beam, a carrying arm mounted at one end of the combination, and at its other end having a swivel mounting. The carrying beam is mounted on a mounting block. The carrying arm is coupled with the mounting block so that the soil preparation device can take up a cooperative working position automatically after each plow body reversal. The carrying arm is adjustably mounted on the mounting block via a pivotable coupling.
Patent DE-69516403-D1 (DE)
Inventor: NERI GIOVANNI
IPC: A61K41/00
Filed: 1995-05-22
Granted: 2000-05-25
Abstract: PCT No. PCT/EP95/01938 Sec. 371 Date Nov. 22, 1996 Sec. 102(e) Date Nov. 22, 1996 PCT Filed May 22, 1995 PCT Pub. No. WO95/32001 PCT Pub. Date Nov. 30, 1995Conjugates of a carrier molecule and an organic molecule producing singlet oxygen after irradiation are useful in diagnostic and therapeutic applications. The organic molecule is a terthienyl or terfuranyl compound derivatized to react with amino, thiol, or saccharide groups of the carrier molecule. Suitable carrier molecules include antibodies, peptides, haptamers, sugars, and other analogous molecules which direct the organic molecule to a biological target.
Patent DE-69519978-D1 (DE)
Inventor: HOLLOWAY THOMAS F
IPC: A45D40/06
Filed: 1995-12-21
Granted: 2001-03-01
Abstract: A cosmetic preparation dispenser (20) is provided that has a helical cam track (40,42) with a horizontal step (48) at its lower end and a longitudinal innerbody track (60,62) that terminates adjacent the horizontal step (48). A cam follower lug (104) of an elevator cup (100) will track into and be trapped by and between the horizontal step (48) and the lower end of the longitudinal track (60,62). This locks the innerbody (50) to the cam sleeve (30) to prevent longitudinal sliding of the innerbody (50) relative to the cam sleeve (30) when, e.g., a lipstick cover is removed in an assembled cosmetic container, which cover removal might leave an undesirable gap between the decorative shells surrounding the innerbody (50) and cam sleeve (30). <IMAGE>
Patent DE-69526708-D1 (DE)
Inventor: BARA ISABELLE
IPC: A61Q1/02
Filed: 1995-08-31
Granted: 2002-06-20
Abstract: Cosmetic compsns. having an oil phase contain: (I) cyclopenta dimethylsiloxanes, and (II) cyclo-hexa dimethylsiloxane.
Patent DE-69527154-D1 (DE)
Inventor: BERGERON MICHEL G
IPC: C12Q1/689
Filed: 1995-09-12
Granted: 2002-07-25
Abstract: The present invention relates to DNA-based methods for universal bacterial detection, for specific detection of the pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus epiderminis, Enterococcus faecalis, Staphylococcus saprophyticus, Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis as well as for specific detection of commonly encountered and clinically relevant bacterial antibiotic resistance genes directly from clinical specimens or, alternatively, from a bacterial colony. The above bacterial species can account for as much as 80% of bacterial pathogens isolated in routine microbiology laboratories. The core of this invention consists primarily of the DNA sequences from all species-specific genomic DNA fragments selected by hybridization from genomic libraries or, alternatively, selected from data banks as well as any oligonucleotide sequences derived from these sequences which can be used as probes or amplification primers for PCR or any other nucleic acid amplification methods. This invention also includes DNA sequences from the selected clinically relevant antibiotic resistance genes.
Patent DE-69532488-D1 (DE)
Inventor: BUTWELL ROBERT J
IPC: B01J19/12
Filed: 1995-04-18
Granted: 2004-03-04
Abstract: A method and apparatus is provided for heating a reaction vessel for use in industrial applications. The apparatus includes a microwave generating device coupled to a waveguide having a means for causing multiple microwave propagation modes prior to directing the microwave into the reaction vessel. The waveguide is mounted to the reaction vessel and directs the microwave in an inclined-angular fashion, thereby generating a helical reflection pattern within the vessel's interior and providing a uniform heating of said interior. An isolation means is also provided, positioned between the microwave generating device and the reaction vessel, which incorporates a quartz window and a sealing means capable of compensating for any disparity in thermal expansion coefficients between the quartz and the material used to house the quartz. <IMAGE>
Patent DE-69533059-D1 (DE)
Inventor: ARDITI MARCEL
IPC: G01S7/52
Filed: 1995-09-21
Granted: 2004-06-24
Abstract: Echographic imaging (such as used for medical diagnosis) uses the injection of specific contrast agents in the body, or more generally in the region to be imaged. Different frequency dependent echographic behavior of the ultrasound contrast agents containing microbubbles as compared to echographic behavior of tissue without contrast agents is exploited by providing separated spectral echo responses and then combining them in ways to enhance image contrast. These imaging principles exploit certain physical "signatures" of the contrast agent responses, allowing increased contrast with respect to tissue background. This contrast enhancement is much larger than what is determined from direct echo amplitude monitoring.
Patent DE-69533477-D1 (DE)
Inventor: SISLER C
IPC: A01N45/02
Filed: 1995-05-22
Granted: 2004-10-14
Abstract: Methods of inhibiting an ethylene response in a plant, inhibiting abscission in a plant or prolonging the life of a cut flower, comprise application of a cyclopropene deriv. of formula (I), a 1,1,1-propellane deriv. of formula (II), or a cpd. isolated from diazocyclopentadiene (DCPD) irradiation by gas chromatography (gc) by elution at about 0.7 min. from a 23% SP-1700 on 80/100 Chromosorb P AW (RTM) glass column: m = 1 or 2; n = 1-3; and R = H, 1-4C satd. or unsatd. alkyl, OH, halo, alkoxy, amino, or carboxy. When the ethylene response is fruit and vegetable ripening, the fruit and vegetables are tomatoes, apples, pears, bananas, papaya, mangoes, peaches, apricots, nectarines, kiwi, pineapple, persimmon, avocadoes, melons, berries, genus Cucumis, green beans, lima beans, lettuce, spinach, cabbage, potatoes, carrots, onions, basil, oregano, dill, soybean, peas, corn, broccoli, cauliflower, and asparagus. When the ethylene response is flower senescence, the flowers are azalea, hydrangea, hibiscus, antirrhinum, poinsettia, cactus, begonia, rose, tulip, daffodil, petunia, carnation, lily, gladiolus, alstromeria, anemone, columbine, avalia, aster, bougainvillea, camellia, bell flower, cockscomb, false cypress, chrysanthemum, clematis, cyclamen, freesia, and orchid. Plants involved in the inhibition of abscission are cotton, apple, pear, cherry, pecan, grape, olive, coffee, snapbean, weeping fig, dormant seedlings, privet, photinea, holly, ferns, schefflera, aglaonema, cotoneaster, etc.
Patent DE-69603016-D1 (DE)
Inventor: WOOD WILLIAM
IPC: A61P31/04
Filed: 1996-03-19
Granted: 1999-07-29
Abstract: A method to inhibit microbial growth is provided comprising topically administering to a mammal afflicted with a pathology associated with microbial growth, such as a dermatological condition, an effective amount of a linear (C12-C22) 3-alken-2-one or 3, omega -alkadien-2-one.