baber/WOPTO huggingface dataset:
Patent NZ-587335-A (NZ)
Title: Lacrimal implants and related methods with implant having drug core
Inventor: JAIN RACHNA
IPC: A61F9/007
Filed: 2009-02-17
Abstract: Lacrimal implants (300) providing secure retention within the lacrimal punctum of an eye are described. The lacrimal implants can comprise a implant body (302) configured for at least partial insertion through the lacrimal punctum and into a lacrimal canaliculus. The implant body can include a deformable retention structure (308) that can be configured to substantially encapsulate an expandable retention element. In some examples, the expandable retention element can include a fluid absorbing material, which can be exposed to fluid such as via a fluid permeable retainer or a fluid permeable aperture (320). As the fluid absorbing material retains fluid (i.e., upon acceptance of fluid into the retention structure), its size increases and its shape can change to urge one or more portions of the retention structure outward, such as against a wall of the lacrimal canaliculus, thereby securely retaining the lacrimal implant within the punctum. The implant has a drug core within the structure that has an agent that in use is released to the eye.
Patent NZ-587540-A (NZ)
Title: Method for amplifying locus in bacterial cell
Inventor: FERRARI EUGENIO
IPC: C12N15/75
Filed: 2009-03-27
Abstract: Disclosed is a method of amplifying a genomic locus comprising: (a) contacting a population of bacterial host cells comprising a genomic locus of the structure: A1-P-M-A2, wherein A1 and A2 are direct repeats, P comprises a coding sequence for a protein of interest, and M comprises a coding sequence for an essential enzyme, with an inhibitor of said essential enzyme; and (b) selecting for cells that are resistant to said inhibitor; wherein cells that are resistant to said inhibitor have multiple copies of said amplification unit.
Patent NZ-590548-A (NZ)
Title: Light-directing lensing member with improved angled light distribution
Inventor: STROM CHRIS
IPC: F21S8/08
Filed: 2009-07-20
Abstract: 590548 A light-directing lensing member for off-axial preferential-side distribution of light from a light emitter having an emitter axis, including a base end with a perimeter-loop line defining a main plane transverse the emitter axis, and an outer surface configured for refracting light from the emitter in a predominantly off-axis direction toward the preferential side. The outer surface includes a major lens-portion and an axially-located minor lens-portion. The major lens portion outer surface has a front region centred on the front side, a back region cantered on the back side, and a middle region around the emitter axis and contiguous with the front and back regions.; The minor lens-portion has a surrounding-loop surface extending from the middle region transverse the main plane and terminating at an end surface configured to direct substantially axially-parallel light from the emitter in off-axis direction toward the preferential side.
Patent NZ-593516-A (NZ)
Title: System and method for detection of target sections in wood pieces
Inventor: LEARMONTH ROBERT EDWARD
IPC: G01N21/01
Filed: 2011-06-16
Abstract: A method and system for locating the position of target wood sections in wood pieces is disclosed. The system comprises: a lighting system, at least one camera, and a processing unit. The lighting system illuminates first and second extremities of each wood piece at a first angle with a first colour, and illuminates the first and the second extremities of each wood piece at a second angle with a second colour, different from the first colour. The camera takes images of the first and the second extremities of each wood piece illuminated by the lighting system. The processing unit: i) receives, from the camera, contrasted images of the first and second extremities of each wood piece; ii) locates and sizes, from the images, a target wood section in each extremity; and iii) determines, from the locating and sizing of the target wood section in each extremity, the location and size of the target wood section along the length of the wood piece between the extremities.
Patent NZ-596370-A (NZ)
Title: Cascade voltage amplifier and method of activating cascaded electron tubes
Inventor: BIRNBACH CURTIS A
IPC: H01J35/00
Filed: 2009-11-16
Abstract: 596370 Disclosed is a cascade voltage amplifier (50) for producing an amplified output in pulse or continuous wave form with a voltage of at least 1000 volts. The voltage amplifier (50) is comprised of at least one non-final stage (54, 56) comprising an electron tube configured as a switching and Class A or C amplifying means; and a final stage (58) comprising an electron tube configured as a switching and Class A or C amplifying means. The at least one non-final stage (54, 56) and the final stage (58) are connected in series. Each stage includes a cylindrical outer electrode (54a, 56a, 58a) encircling at least one concentric cylindrical grid (54b, 56b, 58b) which, in turn, encircles a concentric cylindrical inner electrode (54c, 56c, 58c). The radial spacing from the cylindrical inner electrode (54c, 56c, 58c) to the cylindrical grid (54b, 56b, 58b) is such as to create therebetween a circular waveguide supporting radiation of the transverse electromagnetic mode. Each non-final stage (54, 56) includes a linking structure (60, 62) for electrically joining, and being the primary mechanical support for, the outer electrode (54a or 56a) of said each non-final stage (54, 56) and the inner electrode of a subsequent stage (56c or 58c). Each linking structure (60, 62) has first and second ends with an electrical interconnection included between the first and second ends. The first end includes means for supporting the outer electrode (54a or 56a) of the foregoing stage and the second end includes means for supporting the inner electrode of the subsequent stage (56c or 58c).
Patent NZ-596440-A (NZ)
Title: Method for capturing images of vehicles
Inventor: ABL ALEXANDER
IPC: G08G1/052
Filed: 2011-11-15
Abstract: A method for capturing images (PIC1) of vehicles (1) passing through a section (2) between an entry (3) and an exit (4) at excessive speeds comprises generating a random access identifier (RID) for a vehicle (1) at the entry (3); capturing an image (PIC1) of the vehicle (1) at the entry (3) and storing the entry image (PIC1) and the access identifier (RID) in a first memory (8) which can only be accessed via this access identifier (RID); recording the entry time (TS1) and at least one identifier (LPN1 ) of the vehicle at the entry (3), forming an encrypted or hashed value (h) of this entry identifier (LPN1) and storing the entry time (TS1), the value (h (LPN1)) and the access identifier (RID) as a data set (16) in a second memory (9); recording the exit time (TS2) and at least one identifier (LPN2) of the vehicle (1) at the exit (4), forming an encrypted or hashed value (h) of this exit identifier (LPN2) and ascertaining the data set (16) with the same encrypted or hashed value (h) from the second memory (9) and if the exit time (TS2) lies within a preset time span (tmax ) from the entry time (TS1) of this data set (16), using the access identifier (RID) from this data set (16) for accessing the first memory (8), in order to retrieve the associated stored entry image (PIC1) of the vehicle (1).
Patent NZ-596471-A (NZ)
Title: Compositions and methods for diagnosing, treating, and preventing prostate conditions
Inventor: DONALD CARLTON D
IPC: C12Q1/68
Filed: 2008-01-16
Abstract: NZ 596471 Disclosed is a use of an inhibitor of PAX2 gene expression or PAX2 activity for the manufacture of a medicament for preventing or treating a prostate condition in a subject, wherein the inhibitor is a selective antagonist of PAX2 that directly binds to PAX2 and specifically blocks the binding of PAX2 to the beta defensin-1 (DEFB1) promoter, wherein the selective antagonist is a small molecule, an anti-PAX2 antibody or an oligonucleotide containing the PAX2 binding site of DEFB1 promoter, and wherein the prostate condition comprises prostate intraepithelial neoplasia (PIN) and prostate cancer.
Patent NZ-598288-A (NZ)
Title: Cannabinoid receptor modulators
Inventor: JONES ROBERT M
IPC: C07F9/09
Filed: 2010-08-27
Abstract: IP No. 598288 The present disclosure relates to certain compounds of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB2 receptor. The present disclosure further relates to certain compounds of Formula Ia and pharmaceutical compositions thereof that modulate the activities of both the CB1 receptor and the CB2 receptor. Compounds of the present disclosure and pharmaceutical compositions thereof are directed to methods useful in the treatment of: pain, for example bone and joint pain, muscle pain, dental pain, migraine and other headache pain, inflammatory pain, neuropathic pain, pain that occurs as an adverse effect of therapeutics and pain associated with osteoarthritis; hyperalgesia; allodynia; inflammatory hyperalgesia; neuropathic hyperalgesia; acute nociception; osteoporosis; multiple sclerosis-associated spasticity; autoimmune disorders; allergic reactions; CNS inflammation; atherosclerosis; undesired immune cell activity and inflammation; age-related macular degeneration; cough; leukemia; lymphoma; CNS tumors; prostate cancer; Alzheimer’s disease; stroke-induced damage; dementia; amyotrophic lateral sclerosis, and Parkinson’s disease. Compounds of the disclosure: (1aR,5aR)-2-(5-Chloro-pyridin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diazacyclopropa[a]pentalene-4-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide Phosphoric acid mono-(2-{ [(1aR,5aR)-2-(4-cyano-pyridin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carbonyl]-amino} -2-methyl-propyl) ester (1aR,5aR)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diazacyclopropa[a]pentalene-4-carboxylic acid ((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-amide (1aS,5aS)-(S)-2-Amino-3-methyl-butyric acid (S)-3,3-dimethyl-2-{ [2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carbonyl]-amino} -butyl ester (1aS,5aS)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diazacyclopropa[a]pentalene-4-carboxylic acid ((1S,2S)-2-hydroxy-indan-1-yl)-amide And (1aR,5aR)-2-(4-Fluoro-pyridin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diazacyclopropa[a]pentalene-4-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide
Patent NZ-602230-A (NZ)
Title: Rifaximin powder, process for preparing the same and controlled release compositions containing said rifaximin useful for obtaining a long-lasting effect
Inventor: BRAGA DARIO
IPC: A61K9/14
Filed: 2011-03-04
Abstract: 602230 Provided is a process for the preparation of rifaximin powder having an X-ray diffraction spectrum corresponding to an amorphous form, having a particle size between 40 and 120 micrometres in a percentage of 90% of the total particles as determined by using a Beckman-Coulter LS 100 Q particle size analyser equipped with a micro-volume cell, and a bulk density between 0.1 and 0.5 g/ml as determined by using a 10 ml volumetric flask, characterised by the steps of: a) Solubilisation of crystalline or amorphous rifaximin, or their mixture, in organic solvents or their mixtures; b) Spraying of said solution in fluid bed apparatus at a pressure comprised between 0.5 and 2.5 bar under a flow of warm air; c) Drying the solid rifaximin until constant weight at temperature comprised between 20°C and 120°C. The process produces rifaximin powder with a morphology that contributes, in a pharmaceutical composition, to a prolonged release of rifaximin useful for obtaining a long-lasting antibiotic effect in a patient. Also provided is rifaximin powder as prepared by the process, pharmaceutical compositions comprising the powder, a process for preparing tablets from the pharmaceutical compositions and the use of the powder in the manufacture of a medicament for the treatment of bacterial bowel infections where the medicament provides a controlled release of rifaximin.
Patent NZ-603405-A (NZ)
Title: In-situ electrical stimulation of bioconversion of carbon-bearing formations
Inventor: JIN SONG
IPC: C12N1/38
Filed: 2011-05-11
Abstract: A bioconversion process comprises introducing electrical energy intermittently or continuously into a carbonaceous formation in a manner selected to stimulate a methanogen or methanogenic consortia in the carbonaceous formation to enhance a growth rate of the methanogen or methanogenic consortia, and recovering a formed product from the carbonaceous formation. The formed product recovered from the carbonaceous formation is methane.
Patent NZ-603932-A (NZ)
Title: Treatment of metastatic stage prostate cancer with degarelix
Inventor: PERSSON BO-ERIC
IPC: A61K38/08
Filed: 2009-02-10
Abstract: 603932 Disclosed is the use of a composition including degarelix in the manufacture of a medicament for delaying or preventing the progression of locally advanced prostate cancer to metastatic stage prostate cancer in a subject treated for prostate cancer identified as having prostate specific androgen (PSA) level of 20-50ng/mL, wherein the delaying or prevention is associated with reduced PSA failure rate.
Patent NZ-608028-A (NZ)
Title: Improved method for preparing dipeptidyl peptidase-iv inhibitor and intermediate
Inventor: KWAK WOO YOUNG
IPC: C07C213/00
Filed: 2010-03-30
Abstract: 608028 Disclosed herein is an improved method for preparing a dipeptidyl peptidase-IV inhibitor and intermediate thereof which is able to reduce preparation costs by using low cost reagents on reaction and is able to be used in mass production by improving yield. In one embodiment an intermediate (2) is prepared by a method comprises steps a) reacting an epoxide compound (5) with a Grignard reagent, b) reacting the halogen product (6) with sodium azide, c) reacting the azide product (7) with triphenylphosphine, d) reacting the aziridine product (8) with a cyanogen-based reagent, e) and hydrolysis of the cyanide product (9) with a base.
Patent NZ-613168-A (NZ)
Title: Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof
Inventor: MORRIS JEROME A
IPC: A61K47/10
Filed: 2012-01-13
Abstract: Disclosed herein are compositions comprising photosensitizing agents, in particular lemuteporfin or verteporfin, and their use in photo- dynamic therapy for the treatment of dermatological conditions. In one embodiment the composition comprises a photosensitizing component and an excipient component, such as benzyl alcohol, DGME or isopropyl alcohol, in a solution wherein the concentration of the photosensitizer in the solution is supersaturating.
Patent NZ-618672-A (NZ)
Title: Apparatus and process for continuous carbonisation of wood chips or wastes and other charring organic materials
Inventor: DEEV ALEXANDRE VLADIMIROVICH
IPC: C10B49/02
Filed: 2012-06-19
Abstract: Disclosed is a process for the autogenous production of charcoal, the process comprising: adding dry organic material to a first end of a reaction vessel whereby the organic material progresses along a flow path through the reaction vessel and is removed from a discharge port at a second end of the reaction vessel; heating the organic material in a heating zone of the reaction vessel as it progresses through the reaction vessel to a reaction zone where the temperature of the organic material has reached a sufficient temperature for exothermic autogenous decomposition of the organic material to occur; allowing the organic material in the reaction zone to undergo autogenous decomposition into charcoal and pyroligneous gases; and cooling the charcoal in a cooling zone of the reaction vessel prior to discharge, wherein pyroligneous gases are removed from a reaction zone outlet in the periphery of the reaction vessel such that gases move substantially transversely across the material in the reaction zone towards the reaction zone outlet. Also disclosed is an associated apparatus for the autogenous production of charcoal comprising: a feeder for supplying a heated organic material to a reaction vessel, the reaction vessel for supporting a reaction bed of organic material, and at least one discharge port for discharging thermally decomposed organic material from the reaction vessel, the reaction vessel defining a flow path in which the thermal decomposition of the organic material progresses with the organic material through the reaction vessel; the reaction vessel comprising: a reaction zone for autogenous pyrolysis reaction of organic material in the reaction bed to form pyroligneous gases, a cooling zone having at least one cooling zone inlet for supplying cooling gas into the reaction bed and a cooling zone outlet to extract heated gas from the reaction bed, and at least one lance extending through the reaction bed into the reaction zone to supply a gas into the reaction vessel through a reaction zone inlet in the lance; and a reaction zone outlet provided in the periphery of the reaction zone to remove gas supplied to the reaction zone by the lance, wherein the reaction zone outlet is located transversely from the reaction zone inlet such that gases move substantially transversely across the material in the reaction zone towards the reaction zone outlet.
Patent NZ-624761-A (NZ)
Title: Tag applicator
Inventor: MICHAEL STUART GARDNER
IPC: A01K11/00
Filed: 2013-05-10
Abstract: There is provided a tag applicator (1) for a wrap-around tag (12) which includes first and second pivotally connected jaws (4,5) which are moveable together when applying the tag. The first jaw (5) includes a pin (covered) adapted to receive a male portion (13, 16) of the tag, and the second jaw (4) is adapted to receive a female portion (15) of the tag. One of the jaws includes a guide means (11) adapted to act on a loop portion (14) of the tag (12) connecting the male and female tag portions. The guides means biases the male and female portions of the tag apart prior to engaging these together around an animal’s ear.
Patent NZ-627827-A (NZ)
Title: Antiviral combinations involving (3s, 11ar)-n-[(2,4-difluorophenyl)methyl]-2,3,5,7,11,11a-hexahydro-6-hydroxy-3-methyl-5,7-dioxo-oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
Inventor: UNDERWOOD MARK RICHARD
IPC: A61P31/18
Filed: 2011-01-24
Abstract: Disclosed are combinations of the compound of formula II (3S,11aR)-N-[(2,4-difluorophenyl)methyl]-2,3,5,7,11,11a-hexahydro-6-hydroxy-3-methyl-5,7-dioxo-oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide (also known as cabotegravir and GSK1265744) and rilpivirine or a pharmaceutically acceptable salt thereof. Also disclosed is the use of the combination in the manufacture of a medicament for the treatment of the HIV virus.
Patent NZ-631106-A (NZ)
Title: Lettuce line sv3176lg
Inventor: WILLIAM WAYCOTT
IPC: C12N5/04
Filed: 2014-09-11
Abstract: Disclosed is a lettuce line SV3176LG, a sample of seed of said hybrid having been deposited under ATCC accession number PTA-121369. Further disclosed are seeds, plants and tissue cultures of said lettuce line. Further disclosed are methods of producing and propagating said plants.
Patent NZ-701806-A (NZ)
Title: Gift bag with motorized effects
Inventor: DAVID MAYER
IPC: H02P1/00
Filed: 2014-11-10
Abstract: The present invention is in the field of social expression products, and more specifically to gift wrapping products such as gift bags having motorized effects. Accordingly, the gift bag of the present disclosure combines a traditional gift bag and motorized movement of a mobile object attached thereto and optionally sound capabilities. The gift bag contains a user-interactive switch connected to at least one handle thereof wherein picking up the bag by the at least one handle activates the motor module to initiate movement of the mobile object and the sound module, which is operative to store and playback at least one audio file. The mobile object may be a die cut shape that combines with the artwork on the gift bag to form a larger composite picture, such as an entertaining character. In this regard, the mobile object may represent the mouth of a character or animal printed on the bag. As such, the gift bag provides not only a form of wrapping or cover for a gift but also entertainment for the gift recipient.
Patent NZ-703753-A (NZ)
Title: Smoking article for use with an internal heating element
Inventor: MITREV PANDE
IPC: A24F40/46
Filed: 2013-06-20
Abstract: A smoking article (10) for use in an aerosol-generating device comprises an aerosol-forming substrate (20) located at an extreme upstream end (80) of the smoking article (10); and a support element (30) located immediately downstream of the aerosol-forming substrate (20). The aerosol-forming substrate (20) comprises a gathered crimped sheet of homogenised tobacco material having a plurality of substantially parallel ridges or corrugations, the substantially parallel ridges or corrugations extending along or parallel to the longitudinal axis of the smoking article. Said tobacco material is configured to be penetrable by a heating element (120) of an aerosol-generating device (110) having a diameter of between about 40 percent and about 70 percent of the diameter of the aerosol-forming substrate (20) without bending of the smoking article by more than 7 degrees relative to the longitudinal axis of the smoking article and without tearing or ripping of an outer wrapper of the smoking article. The support element (30) abuts the aerosol-forming substrate (20). The support element (30) is configured to resist downstream movement of the aerosol-forming substrate (20) during insertion of the heating element (120) of the aerosol-generating device (110) into the aerosol-forming substrate (20).
Patent NZ-711367-A (NZ)
Title: Methods of detecting signatures of disease or conditions in bodily fluids
Inventor: KASSIS AMIN I
IPC: G01N33/574
Filed: 2009-01-19
Abstract: An in vitro method for detecting the presence of a cancer cell in an individual comprises isolating a population of phagocytic cells from an individual; separating 2n phagocytic cells from >2n phagocytic cells; determining a first expression profile from the 2n phagocytic cells; determining a second expression profile from the >2n phagocytic cells; comparing the first and second expression profiles; and identifying differential expression of one or more markers specific to the first expression profile. The presence of a cancer cell in the individual is detected based on the differential expression of the one or more markers specific to the first expression profile. Further disclosed is an in vitro method for detecting the presence of an infectious agent in an individual comprising determining a first expression profile from a blood phagocytic cell from an individual; determining a second expression profile from a blood non-phagocytic cell from the individual; comparing the first and second expression profiles; and identifying differential expression of one or more markers specific to the first expression profile. The presence of an infectious agent in the individual is detected based on the differential expression of the one or more markers specific to the first expression profile.
Patent NZ-712934-A (NZ)
Title: Biheteroaryl compounds and uses thereof
Inventor: LYSSIKATOS JOSEPH P
IPC: C07D403/14
Filed: 2014-04-30
Abstract: The present invention provides dual leucine zipper kinase (DLK) inhibitor compounds of Formula I-I and embodiments and salts thereof for the treatment of diseases (e.g. neurodegenerative diseases). R1, R2, R3, X1, X2, A and Cy of Formula (I-I) are as defined herein. In a preferred embodiment X1 is C-R4.
Patent NZ-718978-A (NZ)
Title: Novel treatments for attention and cognitive disorders, and for dementia associated with a neurodegenerative disorder
Inventor: KORTAGERE SANDHYA
IPC: A61K31/4184
Filed: 2014-10-28
Abstract: The present invention provides a method of treating or preventing an attention and/or cognitive disorder in a subject in need thereof, comprising administering to the subject a compound of formula (I). The present invention further provides a method of treating or preventing dementia associated with a neurodegenerative disorder in a subject in need thereof, comprising administering to the subject a compound useful within the invention.