baber/WOPTO huggingface dataset:
Patent DK-0711282-T3 (DK)
Inventor: FENTON GARRY
IPC: A61P17/02
Filed: 1994-07-28
Granted: 2002-09-16
Abstract: This invention is directed to a [di(ether or thioether)heteroaryl or fluoro substituted aryl] compound or an N-oxide thereof or a pharmaceutically acceptable salt thereof, which is useful for inhibiting the production or physiological effects of TNF in the treatment of a patient suffering from a disease state associated with a physiologically detrimental excess of tumor necrosis factor (TNF). Compounds within the scope of the present invention also inhibit cyclic AMP phosphodiesterase, and are useful in treating a disease state associated with pathological conditions that are modulated by inhibiting cyclic AMP phosphodiesterase, such disease states including inflammatory and autoimmune diseases, in particular type IV cyclic AMP phosphodiesterase. The present invention is therefore directed to their pharmacological use for inhibiting TNF and/or cyclic AMP phosphodiesterase, pharmacological compositions comprising the compounds and methods for their preparation.
Patent DK-0730615-T3 (DK)
Inventor: FRIESE CARSTEN
IPC: C08G18/67
Filed: 1994-11-22
Granted: 2001-01-08
Abstract: PCT No. PCT/EP94/03848 Sec. 371 Date Jun. 28, 1996 Sec. 102(e) Date Jun. 28, 1996 PCT Filed Nov. 22, 1994 PCT Pub. No. WO95/14725 PCT Pub. Date Jun. 1, 1995The invention pertains to a composition containing an activator system for free-radical polymerizations and a free-radical polymerizable compound of the general formula II:[H2C=CR1-C(=O)-O-R2-O-C(=O)-NH-Q-NH-C(=O)]2[{-O-R4a-O-C(=O)-NH-Q'-NH-C(=O)}m-O-R4a-O-](II)wherein m is from 0 to 10; R1 is hydrogen or a methyl group; R2 is a linear or branched chain alkyl group containing from 2 to 6 carbon atoms or an alkylene oxide containing from 4 to 21 carbon atoms; Q and Q' independently are aromatic, aliphatic or cycloaliphatic groups containing from 6 to 18 carbon atoms which are derived from the basic diisocyanate or diisocyanate mixtures; and R4a is derived from a polyesterdiol having a C:O ratio of >2.6, a C:H ratio of <10, and a molecular weight of from 1000 to 20,000. The invention further pertains to a process for the preparation of such composition and the use thereof.
Patent DK-0738207-T3 (DK)
Inventor: JOHNSON JAMES P
IPC: B28D1/04
Filed: 1995-01-03
Granted: 1998-12-14
Abstract: A device for cutting cured and uncured (green) pavement including concrete which is capable of cutting a straight groove without the guidance of an operator. The cutting blade is positioned between the front and rear soft contour wheels in a vertical plane which is side-to-side equi-distant between the wheels. The blade, blade drive motor and the wheel drive motor are arranged so that each wheel carries approximately the same weight to enable the cutting device to move, unassisted, in a straight line.
Patent DK-0693975-T3 (DK)
Inventor: PLESTER GEORGE
IPC: C23C16/04
Filed: 1995-02-09
Granted: 1999-11-01
Abstract: Plasma assisted polymerization and deposition of a very thin inner surface coating in a plastic or metal container without an undesirable increase in container surface temperature is provided to change the surface properties of the internal plastic surface of a container by reaction of the surface with a reactive gas which has been energized to produce a plasma or the surface is activated by a plasma of reactive gas so that it becomes receptive to a further surface reaction. It involves locating the container in an enclosure, inserting means for feeding a reactant gas into the container, selectively controlling the pressure inside the enclosure and inside of the container, cleaning a surface of the container to be coated in situ, pretreating the surface to be coated for enabling a polymer coating subsequently deposited thereon to secure proper adhesion between the coating material and the container material, feeding a reactant gas of predetermined constituency and having barrier properties into the container, generating a plasma of said reactant gas and depositing a relatively thin polymer coating on the surface to be coated, and performing a post polymerization treatment on said polymer coating for eliminating residual monomers and other polymer extractables in situ following deposition of said polymer coating.
Patent DK-0755517-T3 (DK)
Inventor: VERSCHOOR JAN ADRIANUS
IPC: C07K16/12
Filed: 1995-04-13
Granted: 2000-05-01
Abstract: The invention relates to a diagnostic test for the detection and identification of Mycobacterium species in biological specimens of human and animal origin. The test is based on the immunological detection of one or more antigens originating from Mycobacterium. To enable the detection of an antibody-antigen reaction, the antibodies specific for these antigens can be labelled with an enzyme or fluorescent dye or attached to latex particles or any other suitable label. The diagnostic test may be in a form of ELISA and may or may not require concentration of the Mycobacterium antigens prior to the actual test. The invention comprises: the selection and procurement of a suitable mycobacterial species and strain, the isolation and purification of the antigens, preparation of the necessary conjugates for the immunization of the experimental animals using various carrier molecules, the development of an assay for monitoring the antibody production, caracterization of the antibodies specific for the Mycobacterium antigen/antigens and the development of a diagnostic assay/kit.
Patent DK-0706488-T3 (DK)
Inventor: GEORG EDGAR
IPC: B65F3/20
Filed: 1995-05-11
Granted: 2000-05-22
Abstract: PCT No. PCT/EP95/01791 Sec. 371 Date Jun. 5, 1996 Sec. 102(e) Date Jun. 5, 1996 PCT Filed May 11, 1995 PCT Pub. No. WO95/31388 PCT Pub. Date Nov. 23, 1995A vehicle for receiving and transporting refuse materials including a collection container including: a front end wall defining a filling opening being bounded by a rigid frame; and a door being movable for opening and closing the filling opening. The vehicle further includes an operating device for moving the door, and a hopper defining an output opening in communication with the filling opening and bounded by a counterframe disposed adjacent the frame for defining a communication region between the hopper and the collecting container. The hopper has a tubular extension extending into the filling opening up to the plane of movement of the door; and a press disposed in the hopper. The press includes a stamp movable into and out of an interior of the collection container through the filling opening, the stamp having an inclined front surface whose upper edge is set back with respect to a lower edge thereof in a direction toward the interior of the collection container. The press further includes a drive operatively connected to the stamp for moving the stamp, the operating device and the drive being configured such that, during a closing of the door, a lower edge of the door remains in contact with the front surface of the stamp during the retracting motion of the stamp until the door is completely closed. The vehicle further includes a seal disposed on an end face of at least one of the frame and the counterframe for sealing the communication region.
Patent DK-0775212-T3 (DK)
Inventor: OLIVER MELVIN JOHN
IPC: C12N15/29
Filed: 1995-07-31
Granted: 2006-02-20
Abstract: A method for making a genetically modified plant comprising regenerating a whole plant from a plant cell that has been transfected with DNA sequences comprising a first gene whose expression results in an altered plant phenotype linked to a transiently active promoter, the gene and promoter being separated by a blocking sequence flanked on either side by specific excision sequences, a second gene that encodes a recombinase specific for the specific excision sequences linked to a repressible promoter, and a third gene that encodes the repressor specific for the repressible promoter. Also a method for making a genetically modified hybrid plant by hybridizing a first plant regenerated from a plant cell that has been transfected with DNA sequences comprising a first gene whose expression results in an altered plant phenotype linked to a transiently active promoter, the gene and promoter being separated by a blocking sequence flanked on either side by specific excision sequences to a second plant regenerated from a second plant cell that has been transfected with DNA sequences comprising a second gene that encodes a recombinase specific for the specific excision sequences linked to a promoter that is active during seed germination, and growing a hybrid plant from the hybrid seed. Plant cells, plant tissues, plant seed and whole plants containing the above DNA sequences are also claimed.
Patent DK-0787363-T3 (DK)
Inventor: FACE DEAN WILLETT
IPC: H01L39/22
Filed: 1995-10-10
Granted: 2000-05-08
Abstract: This invention relates to a process of forming multilayered thallium-containing superconducting composites, wherein a first thallium-containing superconducting layer, an intermediate thallium-containing oxide layer and a second thallium-containing superconducting layer are successively deposited on a substrate by a vapor phase process by controlling the heating temperature, pressure of oxidizing gas and thallium vapor pressure during post-deposition annealing of the superconducting films.
Patent DK-0859777-T3 (DK)
Inventor: MOLDT PETER
IPC: A61P25/24
Filed: 1996-10-11
Granted: 2007-09-03
Abstract: PCT No. PCT/EP96/04449 Sec. 371 Date May 18, 1998 Sec. 102(e) Date May 18, 1998 PCT Filed Oct. 11, 1996 PCT Pub. No. WO97/13770 PCT Pub. Date Apr. 17, 1997A compound having the formula, or any of its enantiomers or any mixture thereof, or a pharmaceutically acceptable salt thereof; wherein R is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl or 2-hydroxyethyl; and R4 is phenyl which may be substituted one or more times with substituents selected from the group consisting of halogen, CF3, CN, alkoxy, cycloalkoxy, alkyl, cycloalkyl, alkenyl, alkynyl, amino, nitro, heteroaryl and aryl; 3,4-methylenedioxyphenyl; benzyl which may be substituted one or more times with substituents selected from the group consisting of halogen, CF3, CN, alkoxy, cycloalkoxy, alkyl, cycloalkyl, alkenyl, alkynyl, amino, nitro, heteroaryl and aryl; heteroaryl which may be substituted one or more times with substituents selected from the group consisting of halogen, CF3, CN, alkoxy, cycloalkoxy, alkyl, cycloalkyl, alkenyl, alkynyl, amino, nitro, heteroaryl and aryl; or naphthyl which may be substituted one or more times with substituents selected from the group consisting of halogen, CF3, CN, alkoxy, cycloalkoxy, alkyl, cycloalkyl, alkenyl, alkynyl, amino, nitro, heteroaryl and aryl. The compounds possess valuable pharmaceutical properties as monoamine neurotransmitter re-uptake inhibitors.
Patent DK-0825688-T3 (DK)
Inventor: GERSTBERGER CHRISTIAN
IPC: H01R33/08
Filed: 1997-07-04
Granted: 2002-10-28
Abstract: A suspended electrical lighting system has a fluorescent light tube (4) that has plug on connectors at each end (6) that are offered up to sockets (12,14) that are located in holes (35) in a carrier panel (3). Mounted on the upper surface of the carrier is an electronic starter circuit module (5) that is preassembled. This has an integral adapter stage (11) that has connecting pins that engage contact bushes (30) within a socket (9) that is fixed to a mounting rail (2) secured to the ceiling. Extensions (15) have embedded power conductors that connect with the sockets in the carrier panel.
Patent DK-0839800-T3 (DK)
Inventor: KAMIHARA SHINJI
IPC: C07D401/12
Filed: 1993-06-18
Granted: 2003-02-24
Abstract: A process for preparing a 2-(1-pyrrolidinyl)acetamide derivative useful as a cerebral function improving agent is disclosed, comprising reacting a halogenoacetamide derivative with substituted or unsubstituted 2-pyrrolidinone, the halogenoacetamide derivative being prepared by reacting an amine and a halogenoacetyl chloride. High yields of the intermediate compound as well as the final product are attained at low cost.
Patent DK-0937456-T3 (DK)
Inventor: NAEFF RAINER
IPC: A61K38/22
Filed: 1998-02-23
Granted: 2004-11-08
Abstract: The present invention relates to a liposome based formulation of erythropoietin comprising:     (a) an effective amount of an erythropoietin;   (b) a lipidic phase comprising:     (i) lecithin or hydrogenated lecithin; (ii) optionally, a charged electropositive or electronegative lipid compound; and (iii) cholesterol or a derivative thereof selected from cholesterol esters, polyethylene glycol derivatives of cholesterol (PEG-cholesterols), and organic acid derivatives of cholesterols; and       (c) a phosphate buffer.   The liposome based parenteral dosage form of the invention is prepared by means of an ethanol injection technique. The composition avoids the need for use of human serum albumin and exhibits superior stability.
Patent DK-0879860-T3 (DK)
Inventor: HAUBENNESTEL KARLHEINZ
IPC: C09D7/45
Filed: 1998-05-11
Granted: 2002-11-11
Abstract: A dispersant based on alkyl acrylate polymers (I) for pigments or fillers, in which the ester groups in the polymer are at least partly converted into acid amide groups. (I) is obtained by aminolysis of the ester groups with (a) amines of formula H2N-R<1>-NR<2>R<3> and/or (b) amines of formula H2N-R<1>-Z, in which R<1> = 2-4C alkylene; R<2>, R<3> = 1-12C (preferably 1-6C) alkyl or cycloalkyl; and Z = a 5- or 6-membered nitrogen heterocycle containing up to 2 nitrogen atoms or additionally oxygen. Also claimed is a process for the production of (I) by aminolysis of acrylate ester polymers with amines (a) and/or (b) as above.
Patent DK-0882709-T3 (DK)
Inventor: PAUST JOACHIM DR
IPC: C07C403/24
Filed: 1998-05-22
Granted: 2001-09-24
Abstract: Preparation of (3R,3'R)-zeaxanthin (I) comprises: (i) reacting (4R)-4-hydroxy-2,2,6-trimethyl-cyclohexanone (II) with dichloromethyl lithium in an inert solvent at -120 to -40 degrees C and warming the reaction mixture to 20-60 degrees C; (ii) reacting the obtained (4R,6R)-1-formyl-2,2,6-trimethyl-7-oxa-bicyclo (2.2.1) heptane of formula (IV) (in isolated form or directly in the reaction mixture) with acetone or a dialkyl (2-oxo-propyl)-phosphonate; (iii) converting the obtained (4R,6R)-1-(3-oxo-but-1-en-1-yl)-2,2,6-trimethyl-7-oxa-bicyclo (2.2.1) heptane of formula (V) into (4R,6R)-1-(3-hydroxy-3-methylpenta-1,4-dienyl)-2,2,6-trimethyl-7-oxa-b icyclo (2.2.1) heptane (VI) by conventional vinylation (or ethynylation followed by partial hydrogenation); (iv) reacting (VI) with a triaryl phosphine (preferably PPh3) and a strong acid to give a mixture of a C15 triaryl phosphonium salt of formula (III) and the isomer of formula (III'); and (v) subjecting 2 moles of the mixture to a double Wittig olefin synthesis reaction with 2,7-dimethyl-octa-2,4,6-triene-1,8-dial (VIII) to give (I). Ar = aryl (preferably optionally substituted phenyl); and X = 1 equivalent of an anion of a strong acid (preferably Cl, Br or HSO4). The preparation of (I) by step (v) is claimed per se. Also claimed are (IV) and (V) and (III') in mixtures with (III).
Patent DK-0990015-T3 (DK)
Inventor: MURJAHN KLAUS
IPC: C09D1/00
Filed: 1998-06-25
Granted: 2003-02-10
Abstract: The present invention relates to a transparent coating agent that comprises a layered silicate capable of forming a colloidal gel in the presence of water. This invention also relates to the preparation of this agent and to its use for reducing the soiling process of facades.
Patent DK-1004320-T3 (DK)
Inventor: BRAUN SERGE
IPC: A61K9/08
Filed: 1999-09-30
Granted: 2003-09-15
Abstract: Described is the use of magnesium (Mg<2+>) for the preparation of a therapeutic composition for the introduction of a polynucleotide into a cell in vivo.
Patent DK-0992758-T3 (DK)
Inventor: BOSS ANDRE
IPC: F42C17/04
Filed: 1999-09-30
Granted: 2007-06-18
Abstract: The method involves multiplying a first correction factor (K) with a speed difference, and adding a result to the division time, whereby the speed difference is formed from a currently measured projectile speed and a nominal speed. The inquiry of the current projectile speed and the correction of the division time is performed after its launch, whereby the speed measurement results in form of the measurement of a first time (t) which requires a certain amount of rotations (Nm) of the projectile, and whereby the speed difference is formed through a difference between the first time and a predetermined second time (tm). An Independent claim is also included for an arrangement for carrying out the above method.
Patent DK-1115319-T3 (DK)
Inventor: HAKIM NOURI E
IPC: A47G21/04
Filed: 1999-08-24
Granted: 2004-02-16
Abstract: A method for feeding a baby using a combination food utensil constructed of materials having different relative hardness, and particularly a spoon. Portions of the spoon are constructed of a hard material such as polypropylene to provide structural rigidity and to allow the utensil to easily slide along the bottom of a dish such as bowl or a plate. Other portions of the spoon are constructed of a softer material such as Kraton or silicone to provide for comfortable contact with the inside of the mouth and gums.
Patent DK-1126821-T3 (DK)
Inventor: CHAUVEAU CHARLES
IPC: A61K9/20
Filed: 1999-11-03
Granted: 2005-08-22
Abstract: The invention concerns an improved multiparticulate tablet disintegrating in the mouth in contact with saliva in less than 40 seconds. The invention is characterized in that it is based on particles of coated active principle, said particles having intrinsic compression properties and a mixture of carriers, the proportion of carrier mixture relative to coated active principle particles being 0.4 to 6 parts by weight, the carrier mixture comprising: a disintegrating agent; a diluting soluble agent with binding properties; a lubricant; a permeabilizing agent; and advantageously lubricants, sweeteners, flavoring and coloring agents, the proportion of disintegrating agent and soluble agent relative to the tablet mass being 1 to 15 wt. % for the former and 30 to 90 wt. % for the latter.
Patent DK-1165270-T3 (DK)
Inventor: ROENNKVIST BO
IPC: B21D19/04
Filed: 1999-12-03
Granted: 2004-09-27
Abstract: A jacket (2) for a vessel (1), arranged to contain a fluid under pressure provided about a central axis (A), with a central portion (9) along the central axis (A), and an end portion (5) at least on one side of said central portion, said end portion comprising an end surface (5a) defining an opening (5b). According to the invention, the end portion (5) forms a portion (8a), at least partially diverging towards the end surface (5a) in a direction along the central axis (A) and in a direction from said central portion (9), against which portion (8a) a closure member (3) is intended to be unreleasably connected. The invention also relates to such a vessel and process for manufacturing the jacket and the vessel, respectively.
Patent ES-2178983-T3 (ES)
Title: Maquina empaquetadora.
Inventor: NATTERER HANS
IPC: B65B7/16
Filed: 2000-03-08
Granted: 2003-01-16
Abstract: Máquina empaquetadora, con un armazón (1), con un lado de entrada (2) y un lado de salida (3), múltiples portabandejas (4) dispuestos uno tras otro sobre una pista desde el lado de entrada hacia el lado de salida para el alojamiento de bandejas (16), y un accionamiento (9, 13) para el movimiento de avance de los portabandejas (4) en un plano de avance, un dispositivo de alimentación para suministrar una película superior (17) para cubrir las bandejas llenas (16), y una estación de sellado (28), estando unidos entre sí de forma articulada los portabandejas (4) sucesivos mediante elementos de unión (6) móviles y presentando cada portabandejas (4) un elemento de engrane (8) en la parte delantera y otro en la parte trasera, caracterizada porque el accionamiento (9, 13) presenta un primer ramal de cadena (9) guiado alrededor de rodillos de inversión (10, 12), en el que engranan los elementos de engrane (8) en su posición adyacente al primer ramal de cadena (9), porque el dispositivo de alimentación presenta un segundo ramal de cadena (21) guiado sobre rodillos de inversión (22, 23) que agarra lateralmente la película superior (17) y que es conducido paralelamente al primer ramal de cadena (9) y a una distancia predeterminada de éste a lo largo de un recorrido predeterminado en un plano paralelo al primer ramal de cadena (9), y porque los elementos de engrane (8) están engranados con el primer o el segundo ramal de cadena (9, 21) como mínimo a lo largo de una sección del recorrido predeterminado.
Patent ES-2258438-T3 (ES)
Inventor: STREUBEL HANS
IPC: B22D11/128
Filed: 2000-12-01
Granted: 2006-09-01
Abstract: Apparatus for changing the size of the casting strand in a continuous casting plant comprises an adjusting device equipped with positioning or power regulation devices. An Independent claim is also included for a process for changing the size of the casting strand in a continuous casting plant. Preferred Features: The casting strand is adjusted to a length of 1-4 m at the start and adjusted to a length of 0.5-2 m at its end.
Patent ES-2199750-T3 (ES)
Inventor: DEVIN JEAN-MARC
IPC: B62D25/10
Filed: 2000-08-25
Granted: 2004-03-01
Abstract: Hood has a torsional resistance greater than 5N/mm and a flexural resistance greater than 55 N/mm. It comprises an outer composite stratified metal sheet skin (1) comprising two outer sheet steel facings and a polymer core of uniform thickness. There is an internal V-shaped reinforcements (2) integral with the skin whose weight is less than 40% of the total hood weight.
Patent ES-2174808-T3 (ES)
Inventor: BEAUFILS PHILIPPE
IPC: A23L5/10
Filed: 2000-05-19
Granted: 2002-11-16
Abstract: The container, which is hermetically sealed by a plastic film cover after filling with the foodstuff, has a base and a false bottom with perforations. A water-soaked pad or humidifier, made from a spongy material containing a chemical or natural flavori agent, is located in the space between the base and false bottom. The film cover has a hole in it covered by a detachable sealing disc or label which can be removed before the container is placed in a microwave oven, the container and cover being made from microwavable materials.
Patent ES-2269094-T3 (ES)
Inventor: STROPPIANA FERNANDO
IPC: E01C13/04
Filed: 2000-08-22
Granted: 2007-04-01
Abstract: The flooring (1) comprises a treading layer (2) extending in a given plane, and supporting formations (5, 6) extending from said treading layer (2) along respective directions of extension, in which at least some (5) of said supporting formations (5, 6) extend with their respective direction of extension (X5), which is oblique with respect to said given plane of the treading layer. The supporting formations (5, 6) comprise first supporting formations (5) in the form of a first array of ribs (5), which are substantially parallel to one another and extend from said treading layer (2) with their respective directions of extension (X5), which are oblique with respect to said given plane of the treading layer, and second supporting formations (6) consisting of a second array of ribs (6), which extend from said treading layer (2) in a substantially orthogonal direction with respect to said given plane of the treading layer (2) and are set crosswise with respect to said first array of ribs (5). <IMAGE>