baber/WOPTO huggingface dataset:
Patent DE-69420566-T2 (DE)
Inventor: BOUR JEAN
IPC: G06F17/00
Filed: 1994-07-25
Granted: 2000-03-30
Abstract: PCT No. PCT/FR94/00930 Sec. 371 Date Mar. 20, 1996 Sec. 102(e) Date Mar. 20, 1996 PCT Filed Jul. 25, 1994 PCT Pub. No. WO95/02991 PCT Pub. Date Feb. 2, 1995An apparatus and process for measuring and processing physiological signals is portable, and have a device for capturing (3, 3'), shaping (4, 4') and digitizing (5) continuously at least one electrocardiographic signal and one signal representing the variation in impedance of a given volume (V) of the body (6) of a patient. A digital preprocessing unit (7) co-operating with control (8) and display (9) devices and a detachable memory (10) for the digitized signals or values token from significant parameters and, finally, by a central digital processing device (12) that collects and stores, by successive transfers, the data from the memory (10) and makes a comparison of them.
Patent DE-69425673-T2 (DE)
Inventor: BRENNAN M
IPC: B01J19/00
Filed: 1994-10-19
Granted: 2001-04-19
Abstract: The present invention provides a polymer synthesis apparatus for building a polymer chain by sequentially adding polymer units in a reagent solution, said apparatus comprising:   a head assembly having a plurality of nozzles mounted thereto in generally spaced-apart relation, each nozzle being coupled to a reservoir of liquid reagent for controlled delivery therethrough; a base assembly having at least one reaction well; a transport mechanism coupled to at least one of said head assembly and said base assembly to produce relative movement therebetween to position said reaction well and a selected one nozzle in alignment for deposition of a liquid reagent into said reaction well for synthesis of a polymer chain; and a sliding seal positioned between said head assembly and said base assembly forms a common chamber enclosing both said reaction well and said nozzles therein.   <IMAGE>
Patent DE-69432248-T2 (DE)
Inventor: CHEVALLIER YVONICK
IPC: C08L21/00
Filed: 1994-09-29
Granted: 2004-08-19
Abstract: Silicas in the form of powder and substantially spherical beads or granules are characterized by a CTAB specific surface of 140 and 240 m2/g a high ultrasonic disaggregation factor, an average diameter, which is small after ultrasonic disaggregation, and optionally, a porous distribution, the porous volume formed by the pores with a diameter of 175 to 275 Å being less than 50% of the porous volume formed by the pores with diameters of 400 Å or less. The silicas may be used as reinforcing fillers for elastomers. The invention also concerns a method for preparing precipitated silica of the type comprising the reaction of an alkaline metal silicate M with an acidifying agent, resulting in a suspension of precipitated silica, and the separation and drying of said suspension, wherein precipitation is performed as follows: (i) an initial seed is formed comprising a portion of the total quantity of alkaline metal silicate M in the reaction, the silicate concentration (expressed as SiO2) in said seed being less than 20 g/l; (ii) an acidifying agent is added to the initial seed until at least 5% of the quantity of M2O in the initial seed is neutralized; (iii) the acidifying agent and the remaining quantity of alkaline metal silicate M are added simultaneously so that the ratio of the quantity of added silicate (expressed as SiO2) to the quantity of silica in the initial seed (expressed as SiO2) is greater than 4 and at most 100.
Patent DE-69505806-T2 (DE)
Inventor: DORNEY TIMOTHY
IPC: G11C29/28
Filed: 1995-04-28
Granted: 1999-05-12
Abstract: An integrated circuit memory device (21) includes plural input/output pins (30, 127 and others) and plural arrays of addressable storage cells (31-46). A set of circuits (51, 68, 70, 71-86, 90) provides access to a unique storage location in each array (31-46) through a given row and column address. A writing circuit (47, 68, 70, 71-86, 91-106, 131-146), designed for test, provides in parallel plural copies of a test data bit. The test data bit is applied through a single pin (30) and a common data-in lead (68), for storage in an addressed storage cell in each of the arrays. A readout circuit (110, 111, 112, 171, 127, 201-216, 131-146) is arranged for reading out the stored test data bit from the addressed storage cell in each of the arrays (31-46). The writing circuit, while in a block write test mode, stores the test data bit on the common data-in lead (68) in a block of address locations in each array (31-46).
Patent DE-69510176-T2 (DE)
Inventor: RUOKONEN MARKKU
IPC: B02C23/04
Filed: 1995-01-27
Granted: 2000-01-05
Abstract: PCT No. PCT/FI95/00041 Sec. 371 Date Jul. 24, 1996 Sec. 102(e) Date Jul. 24, 1996 PCT Filed Jan. 27, 1995 PCT Pub. No. WO95/20435 PCT Pub. Date Aug. 3, 1995The application presents an adjustable cone crusher which has a hydraulic cylinder-plunger-combination (15, 4) for adjusting the setting and supporting a main shaft at its bottom end. The combination contains a bypass channel (21), through which the pressure medium escapes from the cylinder when the combination has been extended by a certain distance. In this way the crushing cone is prevented from rising too much upwards.
Patent DE-69513263-T2 (DE)
Inventor: LESTANI DARIO
IPC: B22D11/14
Filed: 1995-09-13
Granted: 2000-07-13
Abstract: Device for the continuous casting of products having a round cross-section and products having a cross-section with flat sides, which comprises at least a mould (11) with a replaceable crystalliser (12), a downstream mould portion, a containing, guiding and cooling roller conveyor (14) and an extraction and straightening assembly (15), at least the extraction and straightening assembly (15) including drawing rolls (16) with a flat portion (18) and with a longitudinally arranged circumferential outline portion (17) for round products or the like, the lateral reciprocal position of the drawing rolls (16) in relation to the longitudinal axis of the mould (11) being able to be varied from a first position for the casting of round products (13a) to a second position for the casting of products with flat sides (13b). <IMAGE>
Patent DE-69513367-T2 (DE)
Inventor: TABE MASAYASU
IPC: C07D317/34
Filed: 1995-06-07
Granted: 2000-06-08
Abstract: A vitamin D<sub>3</sub> derivative represented by the following formula: wherein, R is, independently, a hydrogen atom, a tri(C<sub>1</sub> to C<sub>7</sub> hydrocarbon)silyl group, a C<sub>2</sub> to C<sub>8</sub> acyl group, or group forming an acetal bond together with an oxygen atom of a hydroxyl group, and A is
Patent DE-69523492-T2 (DE)
Inventor: NAPARSTEK PROF
IPC: G01N33/564
Filed: 1995-02-27
Granted: 2002-07-04
Abstract: The invention provides an immunoassay reagent for the binding and detection of antibodies found in the urine of lupus disease patients, comprising extracellular matrix.
Patent DE-69528770-T2 (DE)
Inventor: NAPOLETANO MAURO
IPC: A61K31/382
Filed: 1995-09-05
Granted: 2003-07-17
Abstract: Compounds of formula (I), wherein R, R', R", Z, m, Y, n, R1, X, p and Ar have the meanings reported in the description; and pharmaceutically acceptable salts thereof are described. The compounds of formula (I) are useful in the treament of arterial hypertension and heart failure, of renal failure, of peripheral arteriopathies, of cerebrovascular insufficiencies and of ischemic cardiopathy.
Patent DE-69533000-T2 (DE)
Inventor: RAYMOND KENNETH
IPC: A61K49/06
Filed: 1995-06-14
Granted: 2005-04-21
Abstract: Disclosed is a series of improved metal chelating agents, selected from the group consisting of: (2), (3) or (4) which are highly effective upon both injection and oral administration; several of the most effective are of low toxicity. These chelating agents incorporate within their structure 1-hydroxy-2-pyridinone(1,2-HOPO) and 3-hydroxy-2-pyridinone(3,2-HOPO) moieties with a substituted carbamoyl group ortho to the hydroxy or oxo groups of the hydroxypyridinone ring. The electron-withdrawing carbamoyl group increases the acidity of the hydroxypyridinones. In the metal complexes of said chelating agents, the amide protons form very strong hydrogen bonds with its adjacent HOPO oxygen donor, making these complexes very stable at physiological conditions. The terminal N-substituents provide a certain degree of lipophilicity to said 3,2-HOPO, increasing oral activity. Also disclosed is a method of making the chelating agents and a method of producing a known compound, 3-hydroxy-1-alkyl-2(1H)-pyridinone, used as a precursor to the chelating agent, safely and in large quantities.
Patent DE-69535273-T2 (DE)
Inventor: BRAACH-MAKSVYTIS LUCIJA
IPC: G01N33/53
Filed: 1995-11-16
Granted: 2007-05-31
Abstract: The present invention provides an analyte detection device. The device comprises first and second zones, means to allow addition of a probe to the first zone, means to allow addition of a sample suspected to contain an analyte and means to allow passage of the probe from the first zone to the second zone. The first zone contains ligands reactive with the analyte and the second zone includes a membrane the impedance of which is dependent on the presence or absence of the probe and means to measure the impedance of the membrane. It is preferred that the probe includes an ionophore, preferably gramicidin. The present invention also relates to methods of detecting the presence of an analyte.
Patent DE-69535604-T2 (DE)
Inventor: VELANDER WILLIAM H
IPC: C12N15/63
Filed: 1995-02-17
Granted: 2008-05-21
Abstract: Transgenic non-human animals, capable of expressing a heterologous gene for human or other recombinant fibrinogen protein or subunit chain polypeptides thereof or modified fibrinogens in mammary glands of the animals and secreting the expressed product into a body fluid, are provided, as are methods of producing recombinant fibrinogens, subunit chains polypeptides thereof and modified fibrinogens, and fibrinogens fusion proteins in such animals.
Patent DE-69605425-T2 (DE)
Inventor: MACLIVER KEVIN SCOTT
IPC: B60N2/28
Filed: 1996-09-06
Granted: 2000-08-03
Abstract: PCT No. PCT/GB96/02210 Sec. 371 Date Mar. 6, 1998 Sec. 102(e) Date Mar. 6, 1998 PCT Filed Sep. 6, 1996 PCT Pub. No. WO97/09194 PCT Pub. Date Mar. 13, 1997The invention relates to a children's safety seat, particularly for the carrying of more than one child. It includes a children's safety seat to be securely and releasably attached to anchorage points in a motor vehicle when positioned on an existing seat of the vehicle. The seat can be provided with a back portion and a base portion which are sub-divided to provide a plurality of individual seats. The seat has integral members to enable it to be anchored in position.
Patent DE-69613347-T2 (DE)
Inventor: MEYER D
IPC: A61P13/02
Filed: 1996-01-11
Granted: 2002-04-18
Abstract: The present invention relates to a compound of the formula   <IMAGE>   and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are  alpha -1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are  alpha -1 antagonist compositions and a method for antagonizing  alpha -1 receptors and treating BPH.
Patent DE-69621501-T2 (DE)
Inventor: BRINON THIERRY
IPC: A61M5/20
Filed: 1996-03-11
Granted: 2003-01-09
Abstract: Liq. injection syringe, designed to enable a patient to self-administer successive doses of medication at controlled intervals of time, consists of a barrel (13) with a chamber (1) having an outlet (1A) and a non-return valve (2), and a rigid piston in two sections (3A, 3B) which fits into the chamber (1) with a lateral seal (4) and has a return spring (5). The reverse movement of the piston is limited by a stop (15A), and the volume of the chamber (1) corresponds to a single dose. A liq. reservoir (8) contg. several doses is in communication with the chamber (1) through a flow limited (9) which controls the time taken for the chamber to re-fill with liquid after one dose has been administered, so that a second dose cannot be taken within a pre-set time.
Patent DE-69624816-T2 (DE)
Inventor: HARBOE HENRIK
IPC: A61M25/00
Filed: 1996-06-07
Granted: 2003-09-11
Abstract: PCT No. PCT/DK96/00251 Sec. 371 Date Dec. 5, 1997 Sec. 102(e) Date Dec. 5, 1997 PCT Filed Jun. 7, 1996 PCT Pub. No. WO96/41653 PCT Pub. Date Dec. 27, 1996The invention relates to a catheter including a tubular part, a closure, a radially projecting part, and an operating handle. The tubular part has a proximal end and a distal end, at least one inlet opening at the proximal end and at least one outlet opening at the distal end. The closure is connected to the tubular part by a first hinge, with the closure extending beyond the first hinge. The radially projecting part projects from the tubular part. The operation handle is connected to the catheter by means of a second hinge at the end of the closure extension, and by means of a third hinge at the radially projecting part. The total length of the closure extension and the operation handle exceeds the rectilinear distance between the first and the third hinges. The catheter according to this invention provides a simple construction, which can be inserted and operated by one hand of the user and at a convenient site, not necessarily over a receptacle for urine or other bodily fluids. The opening/closing mechanism further gives the user the feeling of controlling the act of urination.
Patent DE-69629716-T2 (DE)
Inventor: MULLER W
IPC: A61K31/4015
Filed: 1996-10-04
Granted: 2004-07-08
Abstract: Novel succinimides and maleimides are inhibitors of tumor necrosis factor  alpha  and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory conditions. A typical embodiment is methyl 3-(3',4',5',6'-tetrahydrophthalimido)-3-(3'',4''-dimethoxyphenyl)propionate.
Patent DE-69700899-T2 (DE)
Inventor: DO ROSARIO TEIXEIRA ANTONIO
IPC: B44B5/00
Filed: 1997-02-10
Granted: 2000-07-27
Abstract: The invention deals with a technology for minting coins and medals. The technology is based on the utilization of metal blanks with similar diameters, one being very thin (hereafter named as the foil), joined together by mechanical means during the impartion of the surface details by the minting dies. The technology requires the design and manufacture of a special geometry in the edge of the thicker disk in order to make possible assembly of the metal blanks. The proposed technology is based on a multi-stage manufacturing process consisting of three cold metal forming operations (preforming, rimming and coining) and one intermediate annealing treatment. The first metal forming operation ensures the preforming of the thicker disk blank, hereafter named as the disk. The second metal forming stage is the rimming operation in which the preformed disk is bent along its diameter in order to generate a suitable profile for subsequent assembly with the foil. The third metal forming stage is a coining operation in which the metal blanks (disk and foil) are assembled together, by locking the foil into the rimmed edge of the disk, during the imprint of the surface details. The annealing treatment is to be performed before the coining operation. The goal is to restore the initial ductility of the disk prior to the final coining stage.
Patent DE-69728049-T2 (DE)
Inventor: CHEN WATERSON
IPC: E05B21/06
Filed: 1997-12-29
Granted: 2004-10-28
Abstract: The coded key (90) of a lock apparatus has a head portion (91) and a shank portion (92) which has a cross-section in the form of a circular sector with first and second planar surfaces (93, 94) that extend along the length of the shank portion (92), and a curved surface (95) that interconnects the first and second planar surfaces (93, 94) and that has an arc length greater than 180 DEG . The shank portion (92) is formed with a plurality of key bit projections and key bit grooves on one of the first and second planar surfaces (93, 94). The key bit projections and the key bit grooves have inclined actuating surfaces (921) that form different angles to set the code of the key (90). The angles are in a range from 0 DEG  to about 180 DEG . <IMAGE>
Patent DE-69728943-T2 (DE)
Inventor: BURGERS HENRI T
IPC: H01R13/629
Filed: 1997-09-16
Granted: 2005-06-09
Abstract: A rapid action engagement interface connection system includes a receiver (212) electrically connected or connectable to a testing device. The receiver (212) includes a receiver main body section accommodating a receiver electrical connector assembly (224). The receiver also includes a pivot tab receptacle (214), connected to the main body section, guide grooves (216) in the sides of the main body section, and a locking latch receiver (244) disposed on the main body section. The rapid action engagement interface connection system also includes an interchangeable test adaptor (202) connected or connectable to a device under test. The interchangeable test adaptor includes a test main body section accommodating at least one test electrical connector (218), and a pivot tab (206) connected to the adaptor main body section. The interchangeable test adaptor includes first and second guides (208), connected to the sides of the adaptor main body section, and a locking latch mechanism (210) disposed on the adaptor main body section. <IMAGE>
Patent DE-69730747-T2 (DE)
Inventor: YARKONI SHAI
IPC: A61K47/48
Filed: 1997-06-04
Granted: 2005-09-22
Abstract: The present invention relates particularly to neoplastic cells targeted chimeric toxins comprising of cell targeting moieties and cell killing moieties for recognizing and for destroying the neoplastic cells, wherein the cell targeting moieties consist of gonadotropin releasing hormone homologues and the cell killing moieties consist of Pseudomonas Exotoxin A. The present invention further relates to pharmaceutical compositions containing as an active ingredient these neoplastic cells targeted chimeric toxins and to a method for the production of these chimeric toxins. The said invention also relates to a method for cancer therapy, treating malignant carcinoma cells and benign hyperplasia including uterine leiomyoma cells, extrauterine endometrial island cells, benign hyperplasia of prostate and breast and pituitary tumor adenoma cells, by the use of the above-mentioned chimeric toxins.
Patent DE-69734669-T2 (DE)
Inventor: BRUCE NEIL CHARLES
IPC: C12N1/19
Filed: 1997-10-29
Granted: 2006-05-24
Abstract: The present invention pertains to an enzymatic reaction involving a pyridine nucleotide cofactor, wherein an enzyme is used that has a sequence of greater than 70% identity to SEQ ID NO: 2 and is capable of transferring reducing equivalents between pyridine nucleotide cofactors. Alternatively, a cell transformed to express the enzyme may be used.
Patent DE-69735819-T2 (DE)
Inventor: JANNARD H
IPC: G02C5/06
Filed: 1997-07-24
Granted: 2006-10-26
Abstract: Disclosed are dimensionally stable eyeglass orbitals, pivotably mounted in an eyeglass frame. In one embodiment, the eyeglass orbitals are investment cast from substantially pure titanium or a titanium based alloy.
Patent DE-69736807-T2 (DE)
Inventor: VANHASEBROECK BART
IPC: A61K48/00
Filed: 1997-05-30
Granted: 2007-08-16
Abstract: The invention relates to a novel lipid kinase which is part of the PI3 Kinase family. PI3 Kinases catalyze the addition of phosphate to inositol generating inositol mono, di and triphosphate. Inositol phosphates have been implicated in regulating intracellular signaling cascades resulting in alternations in gene expression which, amongst other effects, can result in cytoskeletal remodeling and modulation of cellular motility. More particularly the invention relates to a novel human PI3 Kinase, p110Delta which interacts with p85, has a broad phosphinositide specificity and is sensitive to the same kinase inhibitors as PI3 Kinase p110A. However, in contrast to previously identified PI3 Kinases which show a ubiquitous pattern of expression, p110Delta is selectively expressed in leucocytes. Importantly, p110Delta shows enhanced expression in most melanomas tested and therefore may play a crucial role in regulating the metastatic property exhibited by melanomas. The identification of agents that enhance or reduce p110Delta activity may therefore prevent cancer metastatis.
Patent DE-69806228-T2 (DE)
Inventor: BATHELIER XAVIER
IPC: D04H1/70
Filed: 1998-02-11
Granted: 2003-02-06
Abstract: A method for producing a textile with adhered pile involves feeding a fibrous net or layer forward. In a pre-looping stage, the fibres are looped transversely to the feed direction. This may be accompanied by transverse stretching. The fibres and/or filaments, formed parallel to each other as loops, then undergo a stage of confinement. This stage takes place directly onto a support, without intervention from transport devices such as needles. Also claimed is the equipment for producing the textile and the textile so produced.
Patent DE-69814264-T2 (DE)
Inventor: BRUNE SCOTT A
IPC: A01K11/00
Filed: 1998-08-21
Granted: 2004-07-29
Abstract: A system and ingestible boluses (2) for monitoring physiological parameters of animals. The boluses include circuitry for storing a selectable identification code, for sensing a physiological parameter, and for transmitting a data burst signal which includes information corresponding to the identification code and a sensed physiological parameter. In addition to the boluses, the system includes a receiver (4) for receiving data burst signals transmitted from the boluses. According to one mode of operation, the bolus transmits data burst continuously at a preselected rate. The receiver can be coupled to a processor which can process data from the data burst signals. <IMAGE>
Patent DE-69815896-T2 (DE)
Inventor: BORGNA FLAVIO
IPC: F25D25/02
Filed: 1998-01-27
Granted: 2004-05-19
Abstract: The invention relates to a shelf (1) for holding articles, especially in refrigeration units, comprising at least one supporting plate (2) embodied by at least one panel made of glass or possibly a plastic material, and at least one corner piece (4, 5, 6, 7) which is preferably made of a plastic material and covers only one corner (8, 9, 10, 11) of the plate. This type of shelf is especially economical.
Patent DE-69820682-T2 (DE)
Inventor: STAM JOSEPH S
IPC: H04N5/335
Filed: 1998-03-26
Granted: 2004-12-09
Abstract: An automatic vehicle head lamp dimming system which includes an optical system and an imaging processing system. The optical system is configured to discriminate between head lamps and tail lamps and focus the light rays from the head lamps and tail lamps on different portions of a pixel sensor array. The optical system as well as the image processing system provides for relatively increased discrimination of head lamps and tail lamps of other vehicles and also enables the high beam head lamps of the control vehicle to be controlled as a function of the distance as well as horizontal angular position of other vehicles relative to the controlled vehicle. <IMAGE>
Patent DE-69823855-T2 (DE)
Inventor: GERBER R
IPC: E21B34/06
Filed: 1998-09-10
Granted: 2005-04-28
Abstract: A valve for dispensing the fluid contents of a container such that external contaminants such as dust, air or microbes cannot enter the container even after repeated dispensing cycles. The valve comprises a plug-type valve and an elastomeric sheath type valve such as a flapper valve, slit valve, or duck bill valve. All are one-way devices. The plug is provided with a mechanism for resetting it to the closed position at the end of each delivery cycle such that the plug is a one-way device also. The mechanism can be an elastomeric tether, gravity, or the deformation of a valve part. The plug can be provided with channels or other cut or shaped features, e.g. grooves, to facilitate fluid flow. The container used with this invention must be volumetrically reducible and thereby maintain its own internal pressure at the end of a delivery cycle. Alternatively, the valve of the present invention can be made without the outlet valve i.e., the flapper, slit, or duck bill valve. In this case, the plug is the only one-way valve mechanism.