baber/WOPTO huggingface dataset:
Patent NZ-274273-A (NZ)
Title: Phenylethyl and phenylpropyl amines and pharmaceutical compositions
Inventor: BENGTSSON STEFAN
IPC: A61P25/18
Filed: 1994-09-16
Abstract: PCT No. PCT/SE94/00860 Sec. 371 Date Oct. 26, 1994 Sec. 102(e) Date Oct. 26, 1994 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/09835 PCT Pub. Date Apr. 13, 1995Compounds of the general formula   <IMAGE>   or pharmaceutically acceptable salts thereof, wherein Z is a saturated or unsaturated 3 to 6 carbon chain, m is 2 or 3, R1 is a hydrogen atom, or a straight or branched C1-4 alkyl group, R2, R3 and R13 are situated in the ortho, meta, or para position of the phenyl ring and are the same or different and selected from the following groups: H, OH, OR14, halogen, CO2R9, CN, CF3, NO2, NH2, COCH3,OSO2CF3,OSO2CH3,CONR10R11, OCOR12, wherein R9, R12 and R14 is a straight or branched C1-4 alkyl group, R10 and R11 are the same or different and represents hydrogen or a straight or branched C1-6 alkyl group, R is 1)   <IMAGE>    or   <IMAGE>   or   <IMAGE>   or   <IMAGE>   wherein the variables are defined in the specification,  processes for their preparation, pharmaceutical preparations containing them and the use of the compounds in the treatment psychiatric disorders.
Patent NZ-277681-A (NZ)
Title: Vaginal pessary comprising topical antimicrobially effective compound and a viable colony of lactobacilli
Inventor: FORD LARRY C
IPC: A61K35/747
Filed: 1994-12-02
Abstract: A vaginal suppository or other type of vaginal passary such as cream, foam or ointment, which contains as its active ingredients at least one pharmaceutically acceptable, topically safe antimicrobial agent, such as an agent selected from the group of benzalkonium chloride, cetylpyridinium chloride, chlorhexidine gluconate and povidone iodine, imidiazolidinyl urea and diazolidinyl urea and a viable colony of micro-encapsulated lactobacilli bacteria. The viable lactobacilli are included in the suppository in micro encapsulated form, which protects the bacteria during storage of the suppository from the action of the bacteriocidal agent. When exposed to the vaginal milieu the micro encapsulation breaks down sufficiently to release the lactobacilli bacteria. The lactobacilli bacteria serve to maintain or re-establish a healthy lactobacilli based flora on the vaginal wall, and excrete hydrogen peroxide and other bactericidins which suppress abnormal flora conditions that promote infections.
Patent NZ-305371-A (NZ)
Title: Automatic packaging apparatus: articles encased in centre folded web
Inventor: EVANGELISTI RICCARDO
IPC: B65B9/067
Filed: 1996-04-05
Abstract: PCT No. PCT/EP96/01505 Sec. 371 Date Dec. 12, 1997 Sec. 102(e) Date Dec. 12, 1997 PCT Filed Apr. 5, 1996 PCT Pub. No. WO96/31397 PCT Pub. Date Oct. 10, 1996A method of packaging includes unwinding a center-folded film from a roller, the center-folded film having a first web and a second web; forming a recess between the first and second film webs; feeding a plurality of products into the thus formed recess, as the film advances, the products spaced apart from each other, and the products having a first and second transverse side; sealing and severing the advancing film between each product to be packaged along each of the two transverse sides of each product so as to form a plurality of bags with one open mouth on a front side of each bag, wherein each bag encloses a respective product; and sealing or clipping each open bag mouth. An apparatus is also disclosed.
Patent NZ-313806-A (NZ)
Title: Nitroxide labelled biological polymer compositions e.g. hemoglobin based red cell substitutes to alleviate free radical toxicity
Inventor: HSIA JEN-CHANG
IPC: A61K47/48
Filed: 1996-03-29
Abstract: Compositions and processes to alleviate free radical toxicity are described based on the use of nitroxides in association with physiologically compatible macromolecules. In particular, hemoglobin-based red cell substitutes are described featuring stable nitroxide free radicals for use in cell-free hemoglobin solutions, encapsulated hemoglobin solutions, stabilized hemoglobin solutions, polymerized hemoglobin solutions, conjugated hemoglobin solutions, nitroxide-labelled albumin, and nitroxide-labelled immunoglobulin. Formulations are described herein that interact with free radicals, acting as antioxidant enzyme-mimics, which preserve nitroxides in their active form in vivo. Blood substitutes, radioprotective agents, imaging agents, agents to protect against ischemia and reperfusion injury, particularly in cerebral ischemia in stroke, and in vivo enzyme mimics among others wherein the composition is of use.
Patent NZ-326574-A (NZ)
Title: Process for making imidazole derivatives with 4-aryl, 5-pyrimidine heterocycle rings
Inventor: SISKO JOSEPH
IPC: C07D401/04
Filed: 1996-12-20
Abstract: he application relates to a method for synthesizing imidazole derivatives having 4-aryl, 5-pyrimidine heterocyclic rings of the formula 1 using  cycloaddition reaction. R1 is optionally substituted pyrimidin-4-yl ring; R4 is optionally substituted phenyl, naphth-1-yl or naphth-2-yl or heteroaryl ring; m is 0,1, or 2 m' is an integer having a value of 1 or 2; R2 is defined in the specification. Also claimed are compounds of the formula VIII, VI where the substituents are defined in the specification.
Patent NZ-335731-A (NZ)
Title: Formulations for modulating the human sexual response comprising a vasodilator
Inventor: LOWREY FRED
IPC: A61K31/22
Filed: 1999-05-12
Abstract: An orally administrable solution for improving the human sexual response comprising a vasodilator, wherein the solution is capable of delivering to the blood, an amount of vasodilator effective to increase blood flow to the genitalia within 1 hour of administration.
Patent NZ-500514-A (NZ)
Title: Indazole derivatives suitable for treating congestive heart failure which also inhibit phosphodiesterase type IV and production of tumor necrosis factor
Inventor: FOSSA ANTHONY ANDREA
IPC: A61K31/00
Filed: 1999-10-20
Abstract: The preparation of a medicament for treating congestive heart failure (CHF) in a mammal by administering an effective amount of a compound that inhibits phosphodiesterase (PDE) type IV and the production of TNF is described. Compounds suitable include substituted indazole derivatives as disclosed in PCT published application WO 97/42174 and include, for example, the compounds of formula (I).
Patent NZ-503633-A (NZ)
Title: Optical lens
Inventor: MORRIS MICHEAL ALAN
IPC: G02C7/02
Filed: 1999-05-26
Abstract: A lens element adapted for mounting in eyewear, the lens element having a spherical surface with a radius of curvature less than about 35 mm, said lens element being adapted for positioning such that a centre of curvature of the lens element is located at the centroid of rotation of the eye, wherein the lens element is sufficiently large to provide a field of view greater than 55 DEG in the temporal direction from the forward line of sight.
Patent NZ-506342-A (NZ)
Title: Railcar braking system
Inventor: WALDROP JEREMY S
IPC: B60T17/22
Filed: 1999-02-16
Abstract: A  pneumatic  railcar braking system  for  freight  or passenger  cars,  wherein  the  system  is  operable  as  an electronically   controlled  pneumatic   brake   system   in conjunction with a head end unit in the locomotive or  as  a conventional  pneumatic brake system in conjunction  with  a pneumatic brake control in the locomotive.
Patent NZ-511985-A (NZ)
Title: Method for covering a food product with collagen using a fraction from a liquid smoke derivative
Inventor: MOELLER PATRICK W
IPC: A23L13/00
Filed: 1999-07-14
Abstract: A method of covering a food product, by arranging directly around the food product by means of extrusion, that includes a collagen processing method for thickening or hardening the collagen sufficiently, by application of a liquid smoke fraction obtained from a liquid smoke derivative, having a pH of at least about 5.0, to harden the collagen, such as Code V which is available commercially [Code V liquid smoke derivative solution comprises: acetic acid in a concentration of about 6.5 to 8.0% weight per unit volume (w/v); carbonyl in a concentration of about 1.0 to 8.0% weight per unit volume (w/v); phenol in a concentration of about 0.1 to 1.0% weight per unit volume (w/v); and water in a concentration of about 83.0 to 92.4% weight per unit volume (w/v)], so that the resultant treated collagen is useful as a casing for a food product. The liquid smoke fraction may be obtained by treating Code V with both carbon and a pH adjustment whereby the method is without an effect on the taste of the food product.
Patent NZ-512023-A (NZ)
Title: Vibratory road roller with hollow drive motor
Inventor: MITSUI AKIRA
IPC: E01C19/28
Filed: 2001-05-29
Abstract: A vibratory roller (R) comprising; a pair of rolls (5) axially supported at both sides of a body (1) in a cantilevered fashion; a pair of vibration generating devices for vibrating each of said rolls; a pair of vibrating motors for driving each of said vibration generating devices; and a pair of roll-driving motors for rotating each of said rolls, wherein said rolls are connected to each other through the roll-driving motors and by a connecting member, where said connecting member is attached to the body through vibration isolating members.
Patent NZ-512168-A (NZ)
Title: Method and device for preparing a mixture of substances containing organic components
Inventor: MULLER PATRICK
IPC: C05F17/02
Filed: 1999-11-04
Abstract: Disclosed is a method for preparing a mixture of substances containing structural components and organic components, in addition to a device for carrying out said method. According to the invention, the mixture of substances is impinged upon with a force in a periodic or pulsed manner to avoid the formation of flow channels for a washing liquid or process air in a heap of debris.
Patent NZ-512295-A (NZ)
Title: Assays for the detection of an antibody corresponding to a polysaccharide antigen that involve the coupling of lipopolysaccharide-derived carbohydrates onto solid surfaces
Inventor: BOAS ULRIK
IPC: H02K16/04
Filed: 1999-12-15
Abstract: A method is provided for immobilising a polysaccharide (PS) to a solid surface, said polysaccharide having a keto-carboxy group (-C(=O)-COOH) or a ketal or hemiketal group corresponding thereto, e.g. derived from 2-keto-3-deoxy-D-mannooctonic acid (KDO).  The method comprises the steps of: (a) forming a covalent bond between the carboxy group of the polysaccharide and a reporter molecule (RM) and further comprises a recognition/substrate site (e.g. biotin or an anthraquinone); and (b) immobilising for diagnostic purposes, e.g. for the detection of bacterial infections from Gram-negative bacteria.
Patent NZ-513296-A (NZ)
Title: C10 carbonate substituted taxol derivatives useful for inhibiting tumour growth
Inventor: HOLTON ROBERT A
IPC: A61K31/337
Filed: 2001-08-01
Abstract: A taxane of formula I is described wherein: R2 is acyloxy; R7 is hydroxy; R9 is keto, hydroxy or acyloxy; R10 is R10aOCOO-; R14 is hydrido or hydroxy; X3 is substituted or unsubstituted alkyl, alkenyl, alkynyl, phenyl or heterocycle, where alkyl comprises at least 2 carbon atoms; X5 is -COX10. -COOX10 or CONHX10; X10 is hydrocarbyl, substituted hydrocarbyl, or heterocyclo; Ac is acetyl; and R10a is hydrocarbyl, substituted hydrocarbyl or heterocycle, where hydrocarbyl comprises at least two carbon atoms, and where a substituted hydrocarbyl is substituted with a group selected from heterocycle, alkoxy, alkenoxy, alkynoxy, aryloxy, protected hydroxy, keto, acyl, acyloxy, nitro, amino, amido, cyano, thiol, ketals, acetals, esters and ethers. Also described are compounds wherein R2 is benzoyloxy, R9 is hydroxy, R14 is H and R7, R10, Ac, X3 and X5 are as defined above, wherein R2 is benzoyloxy, R9 is hydroxy, R14 is H, X3 is cycloalkyl, alkenyl, alkynyl or heterocyclo and R7, R10, Ac, and X5 are as defined above and wherein R2 is benzoyloxy, R9 is keto, R14 is hydrido, X3 is furyl, thienyl or isobutenyl, R10 is EtOCOO- and R7 is hydroxy, Ac is acetyl and X5 is -COOX10 wherein X10 is t-butyl. The compounds are useful for inhibiting tumor growth.
Patent NZ-516955-A (NZ)
Title: Multilayered film containing an active substance and made of cross-linked hydrophilic polymers
Inventor: RUPPRECHT HERBERT
IPC: C08B15/00
Filed: 2000-06-23
Abstract: A multi-layered film which contains an active substance and  which  is  made  of  film-forming  polymers.  The  film comprises  at least one covering layer, at least  one  layer containing  the active substance, and an adhesive  layer.  A method  and  apparatus  for producing such  a  multi-layered film   and  a  preferred  use  as  a  transmucosal   galenic formulation are also disclosed.
Patent NZ-522434-A (NZ)
Title: Treating eczema and/or psoriasis
Inventor: MEAKIN TIMOTHY DAVID
IPC: A61K31/21
Filed: 2001-05-11
Abstract: The use of cetyl myristate in the preparation of a medicament for co-administration with cetyl palmitate in the treatment or prophylaxis of at least the symptoms of eczema and/or psoriasis in a mammal. The use of cetyl palmitate in the preparation of a medicament for co-administration with cetyl myristate in the treatment or prophylaxis of at least the symptoms of eczema and/or psoriasis in a mammal. (62) Divided out of 504525
Patent NZ-523867-A (NZ)
Title: Osteogenic implants derived from bone
Inventor: BOYCE TODD M
IPC: A61L27/36
Filed: 2001-06-27
Abstract: An osteogenic osteoimplant in the form of a flexible sheet comprising a coherent mass of bone-derived particles, the coherent mass formed at least in part from elongate bone-derived elements optionally in combination with bone powder, the osteoimplant possessing an average void volume of not greater than about 32% and methods of making an ostergenic osteoimplant.
Patent NZ-523929-A (NZ)
Title: A patch for use with apparatus for repairing a flaw in a surface, particularly glass
Inventor: RAWLINS PHILIP
IPC: B32B17/10
Filed: 2003-01-31
Abstract: A flexible patch (60) for use with apparatus for repairing a flaw in a surface, which apparatus is of the type in which liquid repair material is introduced into a partly evacuated repair space adjacent the flaw, the patch being of gas and liquid impermeable sheet material and having a ring of adhesive (61) on one side thereof for adhering to the surface around the flaw to be repaired, the patch including at least one slit (62, 63) therein within the ring of adhesive to allow liquid and gas to pass through the or each slit.
Patent NZ-527017-A (NZ)
Title: A biodegradable horticultural or aquacultural non-woven fabric
Inventor: SMITH GERALD MURRAY
Filed: 2003-07-15
Abstract: Disclosed herein is a biodegradable horticultural or aquacultural non-woven fabric suitable for use as a substrate for growing seeds, seedlings and/or plants, or alternatively as a packing material for transporting live fish, shellfish and/or crustaceans, comprising a felt manufactured from predominantly unscoured greasy animal wool, hair or fur. This natural biodegradable felt which is suitable for growing seeds, seedlings or plants comprises a needlepunched felt mat formed of unscoured greasy wool, with or without additional nitrogenous material in the form of crushed or rolled animal excreta (dags). One such mat has a base which is sufficiently dense that it suppresses the growth of weeds through the mat, while being sufficiently loose in the upper surface to enable scattered seeds to be impregnated into the mat, and to grow through the mat when watered. The mat and seeds can be shrink wrapped and rolled to provide an instant lawn. An alternative version uses a different density substrate for use in hydroponics, or for the delivery of growing plants such as lettuce or herbs to supermarkets.
Patent NZ-529245-A (NZ)
Title: Diaryl-enynes
Inventor: EGLE IAN
IPC: C07D333/20
Filed: 2000-11-01
Abstract: Diaryl-enynes of Formula I, wherein: Ar1 and Ar2 are independently selected aryl groups, optionally substituted with up to five substituents independently selected form the group consisting of Alkyl, alkoxy, cycloalkyl, cycloalkyloxy, heterocycloalkyl, heterocycloalkyloxy, alkanoyl, thioalkyl, aralkyl, aralkyloxy, aryloxyalkyl, aryloxyalkoxy, cycloalkyl-substituted alkoxy, cycloalkyloxy-substituted alkoxy, heterocycloalkyloxy-substituted alkoxy, thioaryl, aralkylthio, thioaryl-alkyl, aralkylthioalkyl, halo, NO2, CF3, CN, OH, alkylenedioxy, SO2NRR', NRR', CO2R (where R and R' are independently selected from the group consisting of H and alkyl), a substituent of the formula R"-(X)-, X is CH2, NR, S or OH and R" is aryl substituted optionally with up to three substituents selected form alkyl, halo, NO2, CF3, CN, OH, SO2NRR', NRR' and CO2R, wherein R and R' are independently selected as recited above, and a second a second aryl group which may be substituted as above; R1 is selected from the group consisting of H and alkyl; R2 is selected from the group consisting of H, alkyl and benzyl; R3 is selected from the group consisting of CO2R, CONRR', CONH(OH), COSR, SO2NRR', PO(OR)(OR') and tetrazolyl, wherein R and R' are independently selected form the group consisting of H and alkyl; and pharmaceutical compositions comprising these compounds are disclosed. The compounds described are useful in the manufacture of a medicament for treating a patient having a medical condition for which a glycine transport inhibitor is indicated. In particular, the compounds are useful for treating schizophrenia and cognitive dysfunction.
Patent NZ-529594-A (NZ)
Title: Spray freeze drying of liquid substance with chamber held below triple point of liquid substance
Inventor: CARSON JAMES KENNETH
IPC: A23L3/44
Filed: 2004-05-01
Abstract: The disclosure relates to a process and/or method and associated apparatus for use in spray freeze drying a liquid substance such as fruit juice, pharmaceuticals, nutraceuticals, tea and coffee. A liquid substance is sprayed (atomised) and reduced in temperature to below its eutectic temperature; thereby inducing a phase change of liquids in the liquid substance. The atomised liquid substance (ALS) is then subjected to a vacuum drying chamber in which the ALS is subjected to an energy source to assist sublimation of liquid from the ALS as it is conveyed through the chamber. Such an energy source can provide a temperature gradient through which the ALS passes and is exposed to, all carried out so as to preferably minimise or reduce the likelihood of degradation of the substance being dried (reducing the liquid content).
Patent NZ-531109-A (NZ)
Title: New mandelic acid derivatives and their use as thrombin inhibitors
Inventor: INGHARDT TORD
IPC: C07C69/734
Filed: 2002-08-30
Abstract: Described is the compound Ph(3-Cl)(5-OCHF2)-(R)CH(OH)C(O)-(S)Aze-Pab(2,6-diF)(OH) and pharmaceutically acceptable salts thereof. The compound can be used in medicaments for the treatment of conditions wherein inhibition of thrombin is required or anticoagulant therapy is indicated, such as thrombosis or hypercoagulability in blood and/or tissues.
Patent NZ-534334-A (NZ)
Title: New heterocyclic oxime compounds, a process for their preparation and pharmaceutical compositions containing them
Inventor: LECLERC VERONIQUE
IPC: A61P3/06
Filed: 2004-07-27
Abstract: Disclosed herein are heterocyclic oxime compounds of formula (I), process for their preparation and pharmaceutical compositions containing them, wherein A, B, R1 to R6 and X are as defined in the specification. These oxime compounds are useful as hypoglycaemic and hypolipidaemic agents.
Patent NZ-535690-A (NZ)
Title: Novel flavivirus antigens
Inventor: APT DORIS
IPC: C12N5/06
Filed: 2003-02-26
Abstract: Polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.
Patent NZ-540558-A (NZ)
Title: Tamper evident security document
Inventor: NEMETH JOSHUA ROBERT
IPC: B42D15/10
Filed: 2003-11-14
Abstract: A laminated tamper evident security document (10) is provided which has a transparent or translucent support layer (12), first and second security layers (16, 16') on opposite sides of the support layer (12), first and second tamper evident layers (14, 14') between the support layer (12) and the security layers (16, 16') layers of printed information (22) over the security layers (16, 16') and polymeric outer layers (18). The security layers (16, 16') have security regions (26, 26') which together form a composite security device or image (30) to indicate an authentic security state. Upon exposure to predetermined conditions to delaminate the document, at least one of the tamper evident layers (14, 14') is arranged to destruct or otherwise affect at least one of the security layers (16, 16') to indicate an unauthentic state. In one embodiment each of the tamper evident layers (14, 14') are formed from a weakly coherent or adherent material having a glass transition temperature lower than that of the other layers so that the tamper evident layer (14) separates a portion of the document containing one of the security layers (16) from the remainder of the security document (10) containing the other security document.
Patent NZ-540893-A (NZ)
Title: Selectively activatable food storage wrap sheet including at least one lamina and a deactivator material
Inventor: PALLOTTA SHAWN CHRISTOPHER
IPC: C09J7/20
Filed: 2004-01-16
Abstract: A selectively activatable sheet material is formed from at least one lamina and at least one deactivator material that are in a face-to-face relationship. The at least one lamina comprises an essentially continuous network and at least one face of the at least one lamina and the at least one deactivator has an active disposed thereon. The active is disposable beyond the lamina or the deactivator in response to an application of an external force to the selectively activatable sheet material.
Patent NZ-542406-A (NZ)
Title: Inflammation-inhibiting compounds based on alpha-MSH
Inventor: LUGER THOMAS
IPC: A23L33/18
Filed: 2002-02-08
Abstract: The use of the compound of the formula (I), wherein X is Pro or Pro-Thr, or of a pharmaceutically salt thereof, for the production of a medicament for the treatment and/or prevention of an inflammatory bowel disorder.
Patent NZ-542491-A (NZ)
Title: Benzo[1,2,5]thiadiazole compounds as CCK2 modulators
Inventor: PHUONG VICTOR K
IPC: A61K31/433
Filed: 2004-03-26
Abstract: Disclosed are a compound of formula (I), a pharmaceutical composition comprising a compound of formula (I) and the use of a compound of formula (I) in the preparation of a medicament for treating CCK2 mediated diseases.
Patent NZ-543191-A (NZ)
Title: Reaction vessel coated with a polymer
Inventor: BURNS STEPHEN JOHN
IPC: B01J19/02
Filed: 2004-04-26
Abstract: Disclosed herein is a use of a PFA (perfluoroalkoxy) coated manufacturing vessel in the manufacture of a pharmaceutical formulation comprising a drug substance and pharmaceutically acceptable excipients wherein the drug substance is formoterol fumarate dihydrate. Also disclosed is a manufacturing vessel for the manufacture of formoterol fumarate dihydrate formulations characterised in that the vessel is coated with PFA to reduce adhesion of formoterol fumarate dihydrate.
Patent NZ-546931-A (NZ)
Title: Method for synthesis of perindopril and the pharmaceutically acceptable salts thereof
Inventor: DUBUFFET THIERRY
IPC: C07C309/73
Filed: 2004-11-18
Abstract: The disclosure relates to a method for synthesis of perindopril of formula (I) and the pharmaceutically-acceptable salts thereof.