Patent EP-2223917-A1 (EP)
IPC: A01N43/80
Filed: 2009-02-02
Abstract: Isothiazolyloxyphenylamidine compounds (I) or their salts, N-oxides, metal complexes or stereoisomers are new. Isothiazolyloxyphenylamidine compounds of formula (I) or their salts, N-oxides, metal complexes or stereoisomers are new. Either R 1> : 1-12C-alkyl, 2-12C-alkenyl, 2-12C-alkynyl, cyclic 3-8C-alkyl, 4-8C-alkenyl, 4-8C-alkynyl (where in the ring system the carbon atoms of all the cyclic groups is optionally substituted by one or more heteroatoms of N, O, P or S, and all the groups are optionally substituted by one or more R1a, X, OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2), or H; and R 2> : 1-12C-alkyl, 2-12C-alkenyl, 2-12C-alkynyl, cyclic 3-8C-alkyl, 4-8C-alkenyl, 4-8C-alkynyl, 5-18C-aryl, 7-19C-aralkyl or 7-19C-alkaryl (where: in the ring system the carbon atoms of all the cyclic groups are optionally substituted by one or more heteroatoms of N, O, P or S, and all the groups are optionally substituted by one or more R1a, X, OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2); and R 3> : CN, -SH, -SR2a, -OR2a or -(CO)-R2a; or R 2>R 3>, R 2>R 1>, R 1>R 3>, R 2>R 3>+C, R 2>R 1>+C, R 1>R 3>+C, R 2>R 3>+N, R 2>R 1>+N, R 1>R 3>+N, R 2>R 3>+O, R 2>R 1>+O, R 1>R 3>+O, R 2>R 3>+P, R 2>R 1>+P, R 1>R 3>+P, R 2>R 3>+S, R 2>R 1>+S, R 1>R 3>+S : a 4-7 membered rings (optionally substituted by R1a, OR1a, SR1a, N(R1a) 2or Si(R1a) 3); R1a : H or 1-12C-alkyl; X : halo; R2a : 1-12C-alkyl, 2-12C-alkenyl, 2-12C-alkynyl, cyclic 3-8C-alkyl, 4-8C-alkenyl, 4-8C-alkynyl, 5-18C-aryl, 7-19C-aralkyl or 7-19C-alkaryl (where in the ring system the carbon atoms of all the cyclic groups are optionally substituted by one or more heteroatoms of N, O, P or S, and all the above groups are optionally substituted by one or more R1a, X, OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2); R 4>, R 5> : H, X, CN, SH, SR2a, OR2a or (CO)-R2a; either R 6> : H, X, OR1a, SR1a, N(R1a) 2, nitro, Si(R1a) 3, COOR1a, CN or CON(R1a) 2, 1-12C-alkyl, 2-12C-alkenyl, 2-12C-alkynyl, cyclic 3-12C-alkyl, 4-12C-alkenyl, 4-12C-alkynyl, 5-18C-aryl, 7-19C-aralkyl or 7-19C-alkaryl, where in the ring system the carbon atom of all the cyclic groups are optionally substituted by one or more heteroatoms of C, N, O, P or S, and all the above groups are optionally substituted by one or more R1a, X, OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2; and R 7> : H, 1-12C-alkyl, 2-12C-alkenyl, 2-12C-alkynyl, cyclic 3-12C-alkyl, 4-12-alkenyl, 4-12C-alkynyl, 5-18C-aryl, 7-19C-aralkyl or 7-19C-alkaryl, where in the ring system the carbon atom of the all the cyclic groups are optionally substituted by one or more heteroatoms of C, N, O, P or S, and all the above groups are optionally substituted by R1a, X, OR1a, SR1a, N(R1a) 2, Si(R1a) 3, COOR1a, CN or CON(R1a) 2; or R 2>R 3>, R 2>R 1>, R 1>R 3>, R 2>R 3>+C, R 2>R 1>+C, R 1>R 3>+C, R 2>R 3>+N, R 2>R 1>+N, R 1>R 3>+N, R 2>R 3>+O, R 2>R 1>+O, R 1>R 3>+O, R 2>R 3>+P, R 2>R 1>+P, R 1>R 3>+P, R 2>R 3>+S, R 2>R 1>+S, R 1>R 3>+S : a 4-7 membered rings (optionally substituted by R1a, X, OR1a, SR1a, N(R1a) 2or Si(R1a) 3, COOR1a, CN or N(R1a) 2CO). Independent claims are included for: (1) the preparation of (I); and (2) an isothiazolylaminophenylether compound of formula (VIII). [Image] [Image] ACTIVITY : Fungicide; Antibacterial; Virucide; Antialgal; Herbicide; Plant Growth Stimulant; Pesticide. MECHANISM OF ACTION : None given.