baber/WOPTO huggingface dataset:
Patent NZ-588651-A (NZ)
Title: Methods for manufacturing a polyclonal protein
Inventor: TOLSTRUP ANNE BONDGAARD
IPC: C07K16/00
Filed: 2009-04-23
Abstract: Disclosed is a method for manufacturing a drug product comprising at least two distinct protein members of a polyclonal protein, said method comprising the steps of: a) providing at least two populations of cells, wherein each population encodes one distinct member of the polyclonal protein and is enclosed in a physically separate container comprising culture medium and cells expressing the protein, wherein the method comprises an upstream part comprising the steps of: i) expanding the at least two populations of cells in one or more steps of a seed train in separate containers; ii) expanding cells from the seed train in one or more steps of an inoculum train; iii) culturing cells from the inoculum train in a production phase under conditions favoring expression of the protein members so as to express the at least two distinct protein members; b) harvesting the expressed protein; c) performing at least one downstream purification step on the harvested protein; d) obtaining purified drug substance; and e) formulating purified drug substance into a polyclonal drug product; wherein the at least two populations of cells are kept separate at least during the seed train, and wherein at least part of the downstream purification is carried out on a mixture comprising the individual members of the polyclonal protein.
Patent NZ-595000-A (NZ)
Title: Imidazo[4,5-c]pyridine derivative for treating viral infections
Inventor: BONDY STEVEN S
IPC: A61K31/4745
Filed: 2004-12-21
Abstract: Disclosed are imidazo[4,5-c]pyridine derivative compounds represented by structural formula (C), wherein the variables shown in formula (C) are as defined in the specification. Also disclosed is the use of the compound to treat viral infections such as the hepatitis-C virus, or an infection from a virus belonging to the family of the Flaviviridae or the Picomaviridae or a viral infection from a Coxsackie virus or Bovine Viral Diarrhea Virus.
Patent NZ-595134-A (NZ)
Title: Management system and method
Inventor: CROWHURST ANDREW IAN
IPC: G06Q10/10
Filed: 2010-03-12
Abstract: 595134 An electronic case file and document management system stored on a server having one or more remote terminals coupled thereto and a method for storing documents and managing tasks associated with a case are disclosed. The case file and document management system comprises a content and process application, a case management application, an email application and a mail integration application. The content and process application is operable to provide an electronic case file function for storing and facilitating the display of data relating to one or more cases, and a task management function for creating and displaying data relating to tasks for the one or more cases,. The remote terminals are arranged to access the electronic case file function, the task management function, the email application and the case management application for operation of the electronic case file and document management system. The case management application is coupled to a case management database and case management database is arranged to store data relating to each case, and each case is identified by a unique identifier in the case management application. The electronic case file function is configured to store documentation in a folder structure comprising a plurality of folders and each folder is associated with a related case by the unique identifier of the related case. The electronic case file function is operable, prior to storing the documentation, to carry out a verification of the unique identifier, to determine the existence of a folder related to the verified unique identifier, and, if the folder is determined not to exist, to create the folder such that the folder is able to be subsequently referenced and navigated to.
Patent NZ-598667-A (NZ)
Title: Treated expanded polystyrene foam
Inventor: UPADHYAY NAVNIT BHULESHWAR
IPC: A01N43/40
Filed: 2007-10-12
Abstract: 598667 Disclosed is an expanded polystyrene molded article prepared from a method comprising: contacting expandable polystyrene with imidacloprid in a concentration sufficient to coat the expandable polystyrene when expanded; mixing the imidacloprid with the expandable polystyrene to form a mixture; exposing the mixture to conditions such that the polystyrene beads expand to form a coated expanded polystyrene without being impregnated; and preparing a molded article from the coated expanded polystyrene. Further disclosed is a method for producing an expanded polystyrene foam comprising: an expanded polystyrene formed from the expansion of expandable polystyrene beads having an outer surface; and imidacloprid in the amount of from 0.01 wt/vol.% (lbs/ft3) to less than 1.0 wt/vol.% (lbs/ft3) of the expanded polystyrene, said imidacloprid being operably bound and substantially coating the outer surface of the expanded polystyrene without being impregnated within the expandable polystyrene beads, said expanded polystyrene composition providing upon molding thereof a 0% termite survival rate as determined according to the Standard EI-97 Two Choice Test, wherein said production method comprises the steps of (1) contacting provided expandable polystyrene with imidacloprid in its powder form in a concentration sufficient to coat an outer surface of the expandable polystyrene when expanded; (2) contacting via mixing the imidacloprid with the expandable polystyrene to form a mixture; and (3) exposing the mixture to conditions such that the polystyrene expands to form a coated expanded polystyrene, wherein said imidacloprid is operably bound through electrostatic interactions to and substantially coating the outer surface of the expanded polystyrene.
Patent NZ-602209-A (NZ)
Title: Cross-species-specific psmaxcd3 bispecific single chain antibody
Inventor: KUFER PETER
IPC: A61K39/395
Filed: 2011-04-01
Abstract: Discloses a bispecific single chain antibody molecule comprising a first binding domain which is capable of binding to an epitope of human and Callithrix jacchus, Saguinis Oedipus or Saimiri sciureus CD3ε (epsilon), wherein the epitope SEQ ID NO: 2 ( QDGNEEMGGITQTPYKVSISGTTVILT), SEQ ID NO: 4 (QDGNEEMGDTTQNPYKVSISGTTVTLT). SEQ ID NO: 6 (QDGNEEMGDTTQNPYKVSISGTTVTLT) or SEQ ID NO: 8 (QDGNEEIGDTTQNPYKVSISGTTVTLT) and comprises the amino acid sequence Gln-Asp-Gly-Asn-Glu and a second binding domain capable of binding to prostate-specific membrane antigen (PSMA) wherein the antibody comprises specific CDR regions.
Patent NZ-608860-A (NZ)
Title: Methods and reagents for treatment and diagnosis of age-related macular degeneration
Inventor: HAGEMAN GREGORY S
IPC: C12Q1/68
Filed: 2006-02-14
Abstract: Discloses an isolated complement factor H (CFH) peptide or polynucleotide which comprises tyrosine at position 402 of SEQ ID NO: 2 and the use of said peptide to treat or prevent age-related macular degeneration (AMD). Further discloses an agent which binds to a CFH variant comprising a histidine at position 402 of SEQ ID NO: 2 (Y402H) and the use of said agent to treat macular degeneration.
Patent NZ-615094-A (NZ)
Title: Brassica oleracea plants with improved nutritional value
Inventor: MITHEN RICHARD F
IPC: C12N5/04
Filed: 2013-09-04
Abstract: Disclosed is a Brassica oleracea plant comprising a Myb28 allele from Brassica villosa and lacking an ELONG allele from Brassica villosa genetically linked to said Myb28 allele, wherein the Myb28 allele confers elevated glucosinolates when compared to a plant that lacks the Myb28 allele. Further disclosed is a recombined DNA segment comprising a Myb28 allele from Brassica villosa and an ELONG allele from Brassica oleracea.
Patent NZ-617284-A (NZ)
Title: Rotary surface cleaning tool
Inventor: STUDEBAKER ROY
IPC: A47L11/40
Filed: 2012-05-09
Abstract: A rotary surface cleaning machine is disclosed for cleaning floors, including both carpeted floors and uncarpeted hard floor surfaces including but not limited to wood, tile, linoleum and natural stone flooring. The rotary surface cleaning machine has a rotary surface cleaning tool mounted on a frame and coupled for high speed rotary motion relative to the frame. The rotary surface cleaning tool has a substantially circular operational surface that performs the cleaning operation. The rotary surface cleaning tool is driven by an on-board power plant to rotate at high speed. The rotary surface cleaning tool is coupled to a supply of pressurized hot liquid solution of cleaning fluid and a powerful vacuum suction source. The contact surface has spray nozzles alternating with suction shoes around an annular region with the suction shoes having suction relief grooves each extending in a perpendicular direction to the suction shoe direction. A first plurality of individual delivery spray nozzles includes larger orifices than a second plurality of individual delivery spray nozzles.
Patent NZ-624923-A (NZ)
Title: Device for cooling bulk products
Inventor: ALGOET JO
IPC: F25D3/11
Filed: 2012-11-13
Abstract: Device for cooling bulk products including a drum mounted for axial rotation, the drum has perforations distributed over all or part of its cylindrical lateral wall. The device has a motor which drives the drum as well as a thermally insulated chamber of elongate shape along the axis of the drum and enclosing it. The device has means for cooling the products and in addition to the means for cooling the products, the device also has at least one spray manifold for spraying a liquid cryogen. The spray manifold is situated inside the chamber, opposite a portion of the wall of the drum situated level with the area where the products enter the drum. The spray manifold is able to direct liquid cryogen to the wall portion of the drum and through the wall portion via the perforations, towards the products admitted into the drum.
Patent NZ-705589-A (NZ)
Title: Pyrrolo[3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases
Inventor: RABOISSON PIERRE JEAN-MARIE BERNARD
IPC: C07D487/04
Filed: 2013-10-09
Abstract: There exists a strong need for Toll-Like receptor (TLR) modulators having preferred selectivity, and an improved safety profile. The present invention provides a compound of formula (I) and a pharmaceutically acceptable salt or solvate thereof wherein R1 is H, fluorine or methyl; R2 is H, halogen or C1-3 alkyl; R3 is C1-6 alkyl optionally substituted by aryl optionally further substituted by one or more substituents independently selected from aryloxy, halogen, aryl, alkylamino, dialkylamino, C1-6 alkyl, carboxylic acid, carboxylic ester, carboxylic amide, nitrile, or C1-6 alkoxy; or R3 is C1-6 alkyl optionally substituted by C1-6 alkene, C3-7 cycloalkyl or C3-7 heterocycloalkyl; or R3 is C1-6 alkyl optionally substituted by C1-6 alkoxy optionally further substituted by aryl; R4 is C1-8 alkyl optionally substituted by one or more substituents independently selected from hydroxyl, C1-6 alkoxy, C1-6 alkyl, C3-7 cycloalkyl, C2-6 alkenyl, aryl, heteroaryl optionally further substituted by C1-6 alkyl, and C3-7 cycloalkyl optionally further substituted by C1-6 alkyl; with the proviso that 2-amino, 4-(N-butylamino)-5-(alphamethylbenzyl)pyrrolo[3,2-d] pyrimidine is excluded. Also provdied are pharmaceutical compositions comprising the compounds of the invention and the use of the compounds of the invention in the manufacture of a medicament for the treatment of any disorder in which the modulation of TLR7 and/or TLR8 is involved.
Patent NZ-705706-A (NZ)
Title: Inspectable black glass containers
Inventor: CLICK CAROL A
IPC: G01N33/38
Filed: 2013-10-03
Abstract: A soda-lime-silica glass container (10) related methods of manufacturing. A black-strikable glass composition having a base glass portion and a latent colorant portion is prepared. The base glass portion Includes soda-lime-silica glass materials and one or more blue colorant materials, and the latent colorant portion includes cuprous oxide (Cu2O), stannous oxide (SnO), bismuth oxide (Bi2O3), and carbon (C). Glass containers may be formed from, the back-strikable glass composition, and these glass containers may be heated to a temperature greater than 600 degrees Celsius to strike black therein. The glass containers formed from the black - strikable glass composition may be inspected before or after striking--by infrared inspection equipment.
Patent NZ-706829-A (NZ)
Title: Novel acyltransferase polynucleotides, polypeptides, and methods of use
Inventor: ROBERTS NICHOLAS JOHN
IPC: C07K14/415
Filed: 2013-10-22
Abstract: The invention provides a novel DGAT1 protein with improved properties over known DGAT proteins, particularly known DGAT1 proteins from plants. The novel DGAT1 protein of the invention can be expressed in cells to increase cellular lipid accumulation. Expression of the DGAT1 protein of the invention in cells results in a higher level of lipid than any of several other plant DGAT1 proteins tested by the applicants. The invention provides polynucleotides encoding the novel DGAT1 protein of SEQ ID NO:39, constructs, cells, plant, plant parts and progeny comprising the polynucleotides, and methods of use of the polynucleotides and polypeptides of the invention.
Patent NZ-709195-A (NZ)
Title: Anchor, tensioning device, wind turbine and method for putting tensile element strands under tensile stress on an anchor
Inventor: STRACKE OLAF
IPC: E04H12/16
Filed: 2013-12-02
Abstract: The application relates to an anchor, in particular a stationary anchor, for a tensioning device that is designed to be mounted on a building structure in order to retain tensile element strands, such as cable strands, rods, in particular tensile strands, tie-rods, or the like, on the anchor. Said anchor comprises a multi-part anchor head which includes an anchor plate in the form of a perforated disk that has a through-hole for separately guiding a tensile element strand therethrough, said through-hole being one of a number of through-holes and the tensile element strand being one of a number of tensile element strands. The anchor head further includes an intermediate disk which is arranged on one side of the perforated disk and which has an additional through-hole for separately guiding the tensile element strand therethrough, said additional through-hole being one of a number of additional through-holes in the intermediate disk and the tensile element strand being the one of the aforementioned number of tensile element strands. According to the invention, the intermediate disk is designed as a transition plate which carries a securing sleeve at least in the additional through-hole, said securing sleeve being designed to automatically anchor the tensile element strand under tensile stress.
Patent NZ-710917-A (NZ)
Title: Method and composition for preventing oxidation
Inventor: VITALE ROBERT W
IPC: C09K21/06
Filed: 2014-04-25
Abstract: A composition for inhibiting oxidation includes an anionic, hydrophilic, water soluble polymer, an anionic surfactant, and water. In particular the composition is useful for inhibiting oxidation of coal.
Patent NZ-715797-A (NZ)
Title: Dry powder formulation comprising an anticholinergic, a corticosteroid and a beta-adrenergic for administration by inhalation
Inventor: SCHIARETTI FRANCESCA
IPC: A61K9/00
Filed: 2014-07-10
Abstract: The invention relates to dry powder formulations for inhalation comprising a combination of an anti-cholinergic, a long-acting beta2-adrenoceptor agonist, and a corticosteroid, their process of preparation and therapeutic uses thereof.
Patent NZ-727554-A (NZ)
Title: Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity
Inventor: OOST THORSTEN
IPC: C07D239/70
Filed: 2015-07-30
Abstract: This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.
Patent NZ-739479-A (NZ)
Title: Method, machine and installation for vacuum packaging of products
Inventor: IZQUIERDO EREÑO ENEKO
IPC: B65B51/14
Filed: 2016-06-28
Abstract: The present invention is directed towards improving the generation of vacuum packed products and their transportation to the vacuum chamber to improve the production rate in the complete packaging process. In this respect, the present invention provides a method for vacuum packaging of products, in which a plurality of individual bags closed at one end and open at the opposite end with at least one product therein are generated, from a film in the form of a film tube enveloping therein a plurality of products distributed longitudinally in a forward movement direction, wherein for generating the bags, by means of actuation means, a transverse cut and a complete transverse seal on both sides of the transverse cut are made on the film tube in the forward movement direction, in a first area of the film tube arranged between two adjacent products, and a transverse cut without complete transverse seals on the sides thereof is made in the forward movement direction, in a second area of the film tube separated from the first area in the forward movement direction by a distance substantially equal to the desired length of the bag to be generated, each bag being oriented 180º with respect to the bag previously generated in the forward movement direction.
Patent NZ-746741-A (NZ)
Title: Icos ligand variant immunomodulatory proteins and uses thereof
Inventor: SWANSON RYAN
IPC: C07K14/705
Filed: 2017-04-14
Abstract: Provided herein are immunomodulatory proteins comprising ICOSL variants and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.
Patent NZ-762169-A (NZ)
Title: Stabilizing features in a wear member assembly
Inventor: BILAL MOHAMAD
IPC: E02F9/28
Filed: 2017-05-11
Abstract: A hollow ground-engaging wear member 701 attachable to a support structure 212 may include a leading end 708 arranged to engage ground and a rear end having a cavity 702 formed therein, the cavity 702 having an inner surface and having a longitudinally extending axis 718, the cavity having a front portion 720 and having a rear portion 722 adjacent the rear end, the inner surface having horizontally separated opposing inner walls and having vertically separated opposing inner walls angled with respect to the longitudinally extending axis 718 and forming an upper inner surface and a lower inner surface, the upper inner surface and the lower inner surface each having a centrally disposed, inwardly protruding surface portion 721a arranged to provide a bearing fit with the support structure 212, each inwardly protruding surface portion being disposed only in the rear portion of the cavity and shaped to form an arc 706, the inwardly protruding surface portion being arranged to support vertically imposed loads at the leading end. There are a pair of holes 206 in the respective horizontally separated opposing inner walls, where each hole of the pair of holes is arranged to receive a locking pin. Each hole 206 comprises a portion that is forwardly of each inwardly protruding surface portion 721a.
Patent NZ-764315-A (NZ)
Title: Gear polishing device
Inventor: GUO GANGHAO
IPC: B24B29/02
Filed: 2019-07-30
Abstract: The purpose of the present invention is to provide a gear polishing device which is able to uniformly polish axial surfaces and tooth surfaces of combined gears. The gear polishing device comprises a platform, wherein a polishing mechanism and a transfer mechanism are arranged on the platform; the transfer mechanism comprises a transfer plate; a number of fixation seats are arranged on the transfer plate at equal intervals; the polishing mechanism is arranged on the transfer plate side; a clamping and fastening mechanism is arranged on a lower side of the transfer plate; the clamping and fastening mechanism comprises a third driving mechanism and a fourth driving mechanism; a sucker is fixed on the top of an output end of the third driving mechanism; the sucker is connected to a vacuum generator via an universal air connector; the third driving mechanism is used for controlling the rotation of the sucker, and the fourth driving mechanism is used for adjusting the height of the third driving mechanism; through holes running through the fixation seats from upper and lower sides are formed on the fixation seats; and, when a fixation seat is moved to above the sucker, the fourth driving mechanism lifts up the sucker to fasten and fix the fixation seat, and an air hole of the sucker is communicated with the through hole.
Patent NZ-773979-A (NZ)
Title: Hose and manifold for distributing heated epoxy for spray application
Inventor: WARREN DANNY
IPC: B05D1/34
Filed: 2019-07-03
Abstract: Prior art problems include the material cannot be mixed in large batches prior to application because of the short pot life of the material and the naturally viscous consistency of the mixed epoxy material is not well suited for spray application. A distribution system for delivering preheated epoxy material for spray application includes a bundle of lines that terminate on their far end in a manifold. The distribution system is uniquely constructed in a manner such that it delivers the correct materials individually to the manifold while maintaining separate flows of the materials. This separation of the materials until ready for spraying prevents mixing of the two-part epoxy which at the elevated delivery temperatures would result in early curing of the epoxy within the delivery system itself. The bundle of lines contains at least one and preferably two base epoxy delivery lines, at least one catalyst delivery line and at least one heating circuit. The manifold terminates in a static mixer that in turn delivers the mixed epoxy to a spray head for spray application to the substrate.
Patent PT-100893-A (PT)
Title: Glycol-based stripping agent for varnish coatings - contains butyl di:glycol, alkali, soaps, surfactants, thickener and opt accelerator
IPC: C09D9/00
Filed: 1992-09-23
Abstract: The compsn. contains butyl diglycol free from water, water-soluble substances, alkaline cpds., soaps and surfactants. It is connected to a paste by addn. of usual amounts of a conventional thickener. Opt. it also contains small amounts of butyl glycol or N-methyl 2-pyrrolidone as accelerator of the stripping action.