baber/WOPTO huggingface dataset:
Patent CA-3043408-A1 (CA)
Inventor: WHITLOCK RICHARD P
IPC: F16B37/14
Filed: 2013-02-28
Abstract: A fastener comprises a fastener head having an upper surface with at least five and no more than nine mechanical interlocking sites, each interlocking site including a protrusion extending upward from the upper surface and having an undercut portion proximate to the upper surface; and a dry dielectric layer covering the upper surface of the fastener head, the dry dielectric layer mechanically interlocked with the mechanical interlocking sites.
Patent CA-3045599-A1 (CA)
Inventor: BAEK YI YONG
IPC: C07K7/08
Filed: 2017-12-15
Abstract: The present invention relates to a cytoplasmic transduction peptide and an intracellular messenger comprising the same. Compared with a virus-derived cytoplasmic transduction peptide, the intracellular messenger of the present invention has an advantage of enabling a substance to be effectively delivered into cells even at a low concentration.
Patent CA-3046268-A1 (CA)
Title: Methods for performing dual-comb interferometry
Inventor: BOURBEAU HEBERT NICOLAS
IPC: G01B11/24
Filed: 2017-12-05
Abstract: Methods of performing dual-comb interferometry using a dual-comb interferometer and methods of characterizing a volume using dual-comb interferogram data are described.
Patent CA-3047428-A1 (CA)
Inventor: MOSIG JOHANNA
IPC: A61K9/08
Filed: 2017-12-13
Abstract: The invention relates to new pharmaceutical dosage forms containing potent and selective TASK-1 and/or TASK-3 channel inhibitors, and the use of same to treat and/or prevent breathing disorders including sleep-related breathing disorders such as obstructive and central sleep apnea and snoring.
Patent CA-3051423-A1 (CA)
Title: Systems and methods for a specialized computer file system
Inventor: BLASS OSCAR
IPC: G06F11/14
Filed: 2018-01-29
Abstract: A specialized computer file system for self-managing data storage resources provided as a service to remotely executed applications. The system includes a data storage device configured to store a plurality of data files in a non-relational data store. A storage server is configured to upload a data file to the data storage device to be stored with the plurality of data files. The storage server generate a file link associated with the data file. The storage server transmit the file link to the client application, wherein the client application transmits the file link to an end user. A maintenance server is configured to execute an erase operation to autonomously erase the at least one data file from the data storage device after the data file has been stored in the data storage device for a specified duration of time.
Patent CA-3051774-A1 (CA)
IPC: B62K23/08
Filed: 2019-08-12
Abstract: A pedal-powered wheelchair having a steering dolly pivotally mounted at a rear of the wheelchair. When the upper end of a first steering lever is pulled and the upper end of a second steering lever is pushed, a first steering linkage connected to the first steering lever pulls forward a first side of the steering dolly and a second steering linkage connected to the second steering lever pushes rearward a second side of the steering dolly.  This causes the steering dolly to turn clockwise to initiate a left turn. When the upper end of the first steering lever is pushed and the upper end of the second steering lever is pulled, the first steering linkage pushes rearward the first side of the steering dolly and the second steering linkage pulls forward the second side of the steering dolly. This causes the steering dolly to turn counterclockwise to initiate a right turn.
Patent CA-3054181-A1 (CA)
Inventor: MEDINA RAPHAEL
IPC: B64C13/08
Filed: 2019-09-03
Abstract: A trimmable horizontal stabiliser actuator (THSA) control system 6 for an aircraft is described. The THSA control system 6 uses electronic elements and may replace pre-existing mechanical trim control systems. The THSA control system comprises:  at least one main THSA motor 10 for driving the THSA 8 in response to inputs from a flight control computer (FCC); a pilot trim control system for manual control of the THSA 8 by a pilot overriding the FCC, wherein the pilot trim control system comprises a trim control 2 for receiving an input from the pilot, the trim control 2 including a trim control sensor 18 for detecting the input from the pilot and providing a pilot trim control signal;  a THSA trim control motor 12 for driving the THSA 8 in response to the pilot trim control signal;  and an electronic override system 22 for giving inputs from the pilot priority over inputs from the FCC by preventing the at least one main THSA motor 10 from driving the THSA when an input from the pilot via the pilot trim control system requires a different state for the THSA than an input from the FCC.
Patent CA-3054513-A1 (CA)
Title: Vehicle and track system with pressure-adjustable wheels
Inventor: SAUVAGEAU YVES
IPC: B62D55/08
Filed: 2019-09-06
Abstract: A vehicle includes a plurality of track systems, a fluid pump, a plurality of fluid lines fluidly connecting the fluid pump to at least some of the tires of the wheels of each of the track systems, a plurality of pneumatic inflation actuators, a plurality of pneumatic deflation actuators, and a system controller. The system controller is in electronic communication with the fluid pump, the plurality of pneumatic inflation actuators, and the plurality of pneumatic deflation actuators. The system controller is operable to selectively adjust fluid pressure in select ones of the wheels of any one of the track systems of the vehicle by actuating corresponding ones of the plurality of pneumatic inflation actuators and the plurality of pneumatic deflation actuators. A track system has at least one of the leading idler wheels, trailing idler wheels, and mid-roller wheels including a tire containing a fluid.
Patent CA-3055328-A1 (CA)
Title: Formulations pharmaceutiques contenant des corticosteroides pour administration topique
Inventor: ARTURO ANGEL
IPC: A61P17/00
Filed: 2011-11-09
Abstract: L'activité d'un corticostéroïde topique dans une formulation pharmaceutique est maintenue même lorsque la concentration du corticostéroïde est sensiblement réduite en fournissant le corticostéroïde dans une formulation contenant un composant d'huile liquide qui comprend un ester d'acide dicarboxylique et/ou un ester d'acide monocarboxylique.
Patent CA-3055393-A1 (CA)
Inventor: LOPES DAVID R
IPC: G01M13/022
Filed: 2019-09-12
Abstract: A clutch assembly includes a first gear, a second gear, a first proximity sensor configured to determine a first number of teeth of the first gear that pass by the first proximity sensor within a period of time, and a second proximity sensor configured to determine a second number of teeth of the second gear that pass by the second proximity sensor within the period of time.
Patent CA-3056362-A1 (CA)
Title: Molecules de liaison a fgfr3
Inventor: SILACCI MELKKO MICHAELA
IPC: C07K16/28
Filed: 2018-04-03
Abstract: La présente invention concerne un polypeptide se liant au récepteur 3 des isoformes 3b et 3c (FGFR3b et FGFR3c) du facteur de croissance des fibroblastes, le polypeptide comprenant une séquence d'acides aminés choisie dans le groupe constitué par : (a) GVTLFVALYDYEVYGPTPMLSFHKGEKFQIL(X1)(X2)(X3) (X4)GPYWEARSL(X5)TGETG(X6)IPSNYVAPVDSIQ (SEQ ID NO : 1), les positions des acides aminés (X1) à (X6) pouvant être n'importe quelle séquence d'acides aminés ; (b) une séquence d'acides aminés qui est identique à au moins 95 % à la séquence d'acides aminés de (a), la détermination d'identité excluant les positions des acides aminés (X1) à (X6) et à condition que la séquence d'acides aminés EVYGPTPM (SEQ ID NO : 2) dans les positions d'acides aminés 12 à 19 de SEQ ID NO : 1 est conservée et les acides aminés P et Y dans les positions d'acides aminés 37 et 38 de SEQ ID NO : 1 sont conservés ; (c) GVTLFVALYDYEVMSTTALSFHKGEKF QILSQSPHGQYWEARSLTTGETG(X6)IPSNYVAPVDSIQ (SEQ ID NO : 19), la position d'acide aminé (X6) pouvant être n'importe quel acide aminé ; et (d) une séquence d'acides aminés qui est identique à au moins 95 % à la séquence d'acides aminés de (c), la détermination d'identité excluant la position d'acide aminé (X6) et à condition que les séquences d'acides aminés EVMSTTA (SEQ ID NO : 20) dans les positions d'acides aminés 12 à 18 de SEQ ID NO : 19 et SQSPH (SEQ ID NO : 21) dans les positions d'acides aminés 31 à 35 de SEQ ID NO : 19 sont conservées et les acides aminés Q et Y dans les positions d'acides aminés 37 et 38 de SEQ ID NO : 19 sont conservés.
Patent CA-3057187-A1 (CA)
Inventor: GE XINFENG
IPC: F03B13/00
Filed: 2018-02-02
Abstract: Disclosed is a system for using energy-storing water pipes (1-3) of multiple high-rise buildings to generate electricity, the system comprising an energy-storing water pipe apparatus (1), a lower water pipeline apparatus (2) fitting with the energy-storing water pipe apparatus (1), an underground communicating water intake pipeline (4), an underground pressurised water reservoir (5), a water turbine and an electricity generating system (6), wherein each high-rise building is configured with an energy-storing water pipe apparatus (1) and a lower water pipeline apparatus (2), the energy-storing water pipe apparatus (1), via a water intake pipeline, leading rainwater and daily polluted water into an energy-storing water pipe (1-3); each high-rise building is configured with an underground communicating water intake pipeline (4), the underground communicating water intake pipeline (4) leading water in the energy-storing water pipe (1-3) into the underground pressurised water reservoir (5), the underground pressurised water reservoir (5) balancing the water level in each energy-storing water pipe (1-3), and when the water level in the energy-storing water pipe (1-3) exceeds a certain height H1, starting to generate electricity, and when the water level reduces to H0, stopping electricity generation.
Patent CA-3059725-A1 (CA)
Title: Concussion and sub-concussion monitoring system and method
Inventor: MCEWEN JASON STANLEY
IPC: A61B5/00
Filed: 2019-10-22
Abstract: A method for determining a state of concussion or sub-concussion of an individual by measuring using a monitoring device a plurality of baseline heart rate variability data over a first period of time. The monitoring device transmits said baseline heart rate variability (HRV) data to an application on a smart device. The baseline HRV data is transmitted by said smart device said baseline heart rate variability data to a memory. The monitoring device measures a plurality of contact activity heart rate variability data over a second period of time and transmits the contact activity heart rate variability data to the smart device. The smart device transmits said contact activity heart rate variability data to a memory. A processor analyzes the plurality of baseline heart rate variability data and the plurality of contact activity heart rate variability data in the memory to determine a state of autonomic nervous system dysfunction by comparing the contact activity heart rate variability data with the baseline heart rate variability and communicates said state to said individual via said application on said smart device.
Patent CA-3059769-A1 (CA)
Title: Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
Inventor: LOEW ANDREAS
IPC: C07K14/725
Filed: 2018-04-27
Abstract: Multispecific molecules comprising a non-immunoglobulin heterodimerization domain (e.g., TCRa/ß constant domains), methods of making, and methods of using the same, are disclosed herein.
Patent CA-3059938-A1 (CA)
Title: Complement factor d antagonist antibodies and conjugates thereof
Inventor: PERLROTH D VICTOR
IPC: C07K16/18
Filed: 2018-04-12
Abstract: The present invention provides antagonizing antibodies that bind to complement factor D (CFD), conjugates thereof, and methods of using same. The anti-CFD antibodies can be used therapeutically alone or in combination with other therapeutics to treat age related macular degeneration and other diseases.
Patent CA-3061298-A1 (CA)
Title: Comminuting device
Inventor: DOPPSTADT FERDINAND
IPC: B02C18/14
Filed: 2018-06-06
Abstract: The invention relates to a comminuting device (1) for comminuting material to be comminuted, comprising a machine frame (4), a driven comminuting roller (5), which is mounted on the machine frame (4) and has comminuting tools (22), a comb (26a) having counter-tools (27), and a comb flap (28), which is pivotably mounted on the machine frame (4), wherein the comminuting roller (5) interacts with the comb (26a) for comminution, wherein the comb (26a) is pivotably mounted on the comb flap (28) in the region of the upper end (29) of the comb, wherein at least one spring element (30) acts on the comb (26a) by means of the first end (31) of said spring element and wherein the comb (26a) is resiliently supported by means of the spring element (30). According to the invention, the spring element (30) is supported on the machine frame (4) by means of the second end (32) of the spring element.
Patent CA-3061841-A1 (CA)
Title: Garp-tgf-.beta. antibodies
Inventor: VAN DER WONING SEBASTIAN
IPC: C07K16/28
Filed: 2018-05-11
Abstract: The present invention relates to antibodies and antigen binding fragments thereof, which bind to a complex of GARP and TGF-.beta.1, particularly a complex of human GARP and human TGF-.beta.1. These antibodies and antigen binding fragments exhibit a combination of advantageous properties including high affinity antigen binding and the ability to inhibit the release of active TGF-.beta. from regulatory T cells. The antibodies and antigen binding fragments of the present invention are relatively resistant to deamidation, isomerization and oxidation, such that they display improved stability.
Patent CA-3063217-A1 (CA)
Inventor: FU XIN-YUAN
IPC: C07K16/24
Filed: 2018-05-09
Abstract: L'invention concerne des méthodes pour traiter ou prévenir ou retarder l'apparition de la maladie d'Alzheimer (MA) chez un sujet par ciblage de la nouvelle voie STAT1-CH25H dans la pathogenèse de la MA, spécifiquement grâce à l'administration au sujet d'une quantité pharmaceutiquement efficace d'un inhibiteur de STAT1, d'un inhibiteur de CH25H ou d'un inhibiteur de 25-OHC, par exemple un inhibiteur de la 3-hydroxy-3-méthyl-glutaryl-coenzyme A (HMG-CoA) réductase tel que la simvastatine.
Patent CA-3063634-A1 (CA)
Title: Rotor blade for a wind turbine and wind turbine
Inventor: ALTMIKUS ANDREE
IPC: F03D1/06
Filed: 2018-05-07
Abstract: The invention relates to a rotor blade for a wind turbine, to a wind turbine comprising a tower, a nacelle and a rotor, and also to a wind farm. The rotor blade (108) comprises an inner blade section (2) that extends from a rotor blade root (1) in the longitudinal direction of the rotor blade (108), and a trailing edge segment (40, 74, 112, 112'), arranged on the inner blade section (2), for increasing the profile depth of the rotor blade (108) along a section in the longitudinal direction of the rotor blade. The rotor blade (108) has a pressure-side surface (4, 48) and a suction-side surface (6, 50), which are each formed in certain regions by parts of the inner blade section (2) and of the trailing edge segment (40, 74, 112, 112'). One or more air outlets (24, 68) and air inlets (22, 22', 66) extending substantially in the longitudinal direction of the rotor blade are formed on both the pressure-side surface (4) and the suction-side surface (6) of the rotor blade (108), in the region of the trailing edge segment (40, 74, 112, 112'), said air outlets and air inlets being interconnected in a fluid-guiding manner. At least one covering element (26, 26', 60) overlapping the at least one air outlet (24, 68) and by means of which which the air outlet (24, 68) can be closed or opened is arranged on the suction-side surface (6).
Patent CA-3065758-A1 (CA)
Title: Shipping system for storing and/or transporting temperature-sensitive materials
Inventor: RIZZO ANTHONY
IPC: B65D81/18
Filed: 2018-05-09
Abstract: Shipping system for storing and/or transporting temperature-sensitive materials. In one embodiment, the system includes an outer box having four side walls, bottom closure flaps, and top closure flaps. A vacuum insulated panel (VIP) is detachably coupled to one of the top closure flaps and is removably covered by a cover. An insulation unit is removably positioned within the outer box, the insulation unit including a plurality of VIPs arranged to define a cavity bounded by a bottom wall and four side walls. A disposable liner is removably mounted on the insulation unit. The liner may be a thermoformed sheet and may cover the interior and top surfaces of the insulation unit. A plurality of temperature-control members and a product box may be removably positioned in the liner. Preferably, the liner is shaped so that the temperature-control members snugly fit around all sides of the product box.
Patent CA-3066081-A1 (CA)
Inventor: ARGENTO CLAUDIO
IPC: A61F9/00
Filed: 2018-06-07
Abstract: La présente invention concerne une lentille intraoculaire à puissance réglable comprenant un réservoir, un fluide optique situé dans le réservoir et une substance de transport en solution avec le fluide optique. Le réservoir comporte un composant optique et un composant périphérique se prolongeant autour d'au moins une partie du composant optique. Le composant optique comporte un élément optique antérieur, un élément optique postérieur et un compartiment pour fluide présentant un volume de compartiment situé entre l'élément optique antérieur et l'élément optique postérieur. La substance de transport est conçue pour traverser le réservoir. La lentille intraoculaire à puissance réglable comprend en outre des éléments de régulation du volume situés dans le réservoir. Les éléments de régulation du volume sont conçus pour être activés par une énergie non invasive et pour, suite à leur activation, libérer la substance de transport dans le fluide optique pour faire diminuer le volume du compartiment et/ou absorber la substance de transport hors du fluide optique afin augmenter le volume du compartiment.
Patent CA-3066260-A1 (CA)
Inventor: DELMONTE ALBERT J
IPC: A61K31/47
Filed: 2018-06-29
Abstract: L'invention concerne des procédés améliorés de préparation de composés quinolinylcyclohexylpropanamide substitués.
Patent CA-3066576-A1 (CA)
Inventor: CHUTTER GEOFF
IPC: A63G21/18
Filed: 2018-06-08
Abstract: A waterslide feature for providing a looping travel path for a rider traveling thereon and method for making the same. The waterslide feature may be in the shape of a tilted bowl or saucer that provides a 360 degree travel path for a rider around the waterslide feature. The rider may experience a feeling of weightlessness at one or more locations (e.g., art apex) of the travel path. The rider may be provided into the tilted bowl by way of an entrance (e.g., flume) and may be received from the tilted bowl by way of an exit (e.g., flume). The orientation of the entrance and exit may be in any of a variety of configurations, such as side-by-side or over-under. Colored fiberglass, lighting dements, and other features may be included to enhance the visual or other impact of the waterslide feature to riders and/or spectators.
Patent CA-3066778-A1 (CA)
Title: Methods for treating cancer
Inventor: PARASURAMAN SUDHA
IPC: A61K39/395
Filed: 2018-06-21
Abstract: The present invention relates to methods of treating cancer, in which a CXCR4 inhibitor such as X4P-001 or a pharmaceutically acceptable salt thereof or pharmaceutical composition thereof is administered in combination with an additional therapeutic agent, such as an immune checkpoint inhibitor. The methods demonstrate surprising results, including regression of disease, with comparatively little toxicity.
Patent CA-3066908-A1 (CA)
Inventor: BAARDSETH PERNILLE
IPC: A23L5/20
Filed: 2018-06-19
Abstract: L'invention concerne des procédés de réduction d'acrylamide pendant une cuisson à haute température d'aliments contenant des hydrates de carbone, en particulier des légumes ou des tubercules qui sont cuits dans une friture. L'invention concerne notamment un procédé de réduction de l'acrylamide pendant la cuisson d'un aliment contenant des hydrates de carbone, ce procédé comprenant au moins les étapes suivantes consistant à : mettre en contact cet aliment avec un premier acide a-hydroxy choisi parmi les acides malique, lactique ou tartrique à un pH inférieur ou égal au pK a ou au pK a le plus bas de celui-ci ; cuire partiellement cet aliment à une température à laquelle la réaction de Maillard se produit pour former un aliment partiellement cuit ; le cas échéant, emballer et/ou stocker cet aliment partiellement cuit ; mettre en contact cet aliment partiellement cuit avec un second acide a-hydroxy choisi parmi les acides lactique, malique ou tartrique à un pH inférieur ou égal au pK a ou au pK a le plus bas de celui-ci ; et ensuite cuire à nouveau cet aliment à une température à laquelle la réaction de Maillard se produit.
Patent CA-3067749-A1 (CA)
Title: Method for processing biomass by co-grinding with a fossil-based feedstock
Inventor: PLENNEVAUX THOMAS
IPC: C10L5/44
Filed: 2018-07-03
Abstract: The present invention relates to a method for processing a biomass-containing feedstock, said method comprising the following steps: a) a step of drying said feedstock at a temperature between 20 and 80°C for a duration of between 5 and 180 minutes, b) a step of torrefaction of the dried feedstock coming from step a) in order to produce at least one solid torrefied biomass effluent, and c) a step of co-grinding the solid torrefied biomass effluent from step b) in the presence of at least one solid fossil-based feedstock in order to obtain a powder.
Patent CA-3068583-A1 (CA)
Title: Early strength enhancing concrete admixure
Inventor: YORDAKUL EZGI
IPC: B28B7/46
Filed: 2018-06-27
Abstract: The present invention provides an admixture composition comprising a liquid suspension of colloidal silica, siloxane, and polycarboxylate polymer cement dispersant for enhancing early age strength, finishability, and other properties in hydratable cementitious compositions such as concrete (e.g., shotcrete). An inventive method involves mixing the components together in a specific sequence, thereby to obtain a stable liquid suspension. This attainment of a stable liquid suspension is surprising and unexpected because (i) the polycarboxylate polymer cement dispersant and siloxane components are incompatible and immiscible with one another; and (ii) that colloidal silica and siloxane compound are incompatible and immiscible with one another. Yet, the present inventors achieved an additive in the form of a stable liquid suspension which can be conveniently dosed into concretes and shotcrete mixtures, to enhance early age strength, and to improve workability and rheology in terms of finishability of concrete surfaces and improved rebound performance in shotcrete applications.
Patent CA-3070723-A1 (CA)
Title: Co-electrolysis cell design for efficient co2 reduction from gas phase at low temperature
Inventor: PATRU ALEXANDRA
IPC: H01M8/1053
Filed: 2018-05-24
Abstract: A membrane electrode assembly for an electrochemical cell, in particular a co-electrolysis cell for CO2 reduction reaction, can overcome the problem of parasitic CO2 pumping from cathode to anode side and, at the same time, maintain good Faradaic efficiency towards CO2 reduction reaction in a co-electrolysis system where pure or diluted gaseous CO2 is used. The assembly includes an MEA, having an anode, a cathode, a polymer ion exchange membrane between cathode and anode, an additional ion exchange polymer film between the cathode and the polymer ion exchange membrane and a discontinuous interface formed between the additional polymer film located at the cathode side and the ion exchange membrane.