baber/WOPTO huggingface dataset:
Patent CA-2673095-A1 (CA)
Inventor: LOMBARDI BORGIA ANDREA
IPC: A61P35/00
Filed: 2007-12-14
Abstract: La présente invention concerne des dérivés d'indazole substitués de formule (I) et leurs sels pharmaceutiquement acceptables, tels que définis dans le mémoire descriptif, leur procédé de préparation et des compositions pharmaceutiques qui les comprennent. Les composés selon l'invention ont une utilisation thérapeutique pour le traitement de maladies associée à une activité protéine-kinase déréglée telles que le cancer. Formule (I)
Patent CA-2674546-A1 (CA)
Inventor: ROMEIJN ANDREAS
IPC: A01N47/38
Filed: 2008-01-16
Abstract: The present invention relates toa method for protecting a plant against a phytopathogen selected from the genera Pythium andRhizoctonia,wherein the seed of the plantis treated with (a) triticonazole or anagriculturally acceptable salt thereof and (b) prochloraz or anagriculturally acceptable salt thereof.
Patent CA-2680128-A1 (CA)
Title: Lay flat book sheets
Inventor: HOLMBERG THOMAS A
IPC: B42F5/00
Filed: 2008-03-05
Abstract: A sheet stock having a flexible hinge area is described. The sheet stock includes a substrate having an opening and gap stiffener, and a flexible film covering the opening and defining a flexible hinge area in the region of the opening and gap stiffener covered by the film. Methods for producing sheet stock having a flexible hinge area are also described. The sheet stock may be used in printing, binding, and in other applications.
Patent CA-2681568-A1 (CA)
Inventor: MOLLER THORLEIF
IPC: C12N15/11
Filed: 2007-11-23
Abstract: The present invention describes oligonucleotides that bind to microRNA target sites in target RNAs, such as mRNAs. The oligonucleotides of the invention may mediate RNase H degradation of the target RNA, mediate RNAi of the target RNA or prevent microRNA regulation of the target RNA. The oligonucleotides of the invention are useful e.g. as research tools for studying microRNA:mRNA interactions and for therapeutic development. The present invention also describes methods of identifying microRNA target sites, methods of validating microRNA target sites, methods of identifying oligonucleotides of the invention and methods of modulating the activity of a target RNA using the oligonucleotides of the invention.
Patent CA-2681753-A1 (CA)
Title: Antioxidant blends for fatty acid methyl esters (biodiesel)
Inventor: ZHAO GANGKAI
IPC: C10L1/02
Filed: 2008-03-13
Abstract: This invention provides stabilized biodiesels comprising (1) biodiesel, such as fatty acid methyl ester (FAME), (2) mono- or bis-hindered phenolic derived from 2,6-di-tert- butylphenol, and (3) N,N'-di-substituted para-phenylene diamine. Also methods of stabilizing biodiesel are provided involving adding (2) and (3) to (1).
Patent CA-2682831-A1 (CA)
Inventor: COULSON JOHN LAWRENCE
IPC: B65D51/18
Filed: 2007-04-02
Abstract: An improved closure apparatus comprising generally of cylindrical members and varied pourable cylindrical spout apparatuses The apparatus comprises an inner sealer ring assembly with a permanent tamper evident seal which mates directly on the neck of a container, the apparatus further comprises an optional spout, funnel, top stopper plug or a multitude of novelty apparatus mechanisms The closure has, but not limited to having a two-piece configuration The pieces of the closure are affixed together to form a one-piece solid construction in its basic form The inner sealer ring assembly hermetically seals and reseals containers during primary use During primary use, the apparatus remains is attached to its mated container so there is reduced throw away and containment of residual liquids and other viscous and pourable materials, condiments and dry goods, preventing splashing and spillage The apparatus further comprises a valve control which performs as an adjustable flow control mechanism that enables atmosphere in, as product is dispensed, reducing gurgling, burping and spitting.
Patent CA-2682876-A1 (CA)
Inventor: KISSE BRANDON J
IPC: E02F3/627
Filed: 2008-03-19
Abstract: The application discloses embodiments of a universal pinning system for (200, 250) lift arms (120, 140) of a power machine or vehicle. In embodiments disclosed, the universal pinning system (200, 250) includes a universal shaft (202). Lift arms (120, 140) are coupled to the universal shaft (202) to provide a common pivot axis (212) for the lift arms (120, 140). The universal shaft (202) is coupled to a frame or support of the power machine or vehicle via a pinning assembly. As disclosed, the universal pinning system (200, 250) has application for radial lift arms (120) operable along a radial path or vertical lift arms (140) operable along a vertical path.
Patent CA-2684454-A1 (CA)
Title: Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
Inventor: DESAI NEIL P
IPC: A61K31/337
Filed: 2000-05-19
Abstract: In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug paclitaxel) in which the pharmacologically active agent is delivered in the form of suspended particles coated with protein (which acts as a stabilizing agent). In particular, protein and pharmacologically active agent in a biocompatible dispersing medium are subjected to high shear, in the absence of any conventional surfactants, and also in the absence of any polymeric core material for the particles. The procedure yields particles with a diameter of less than about 1 micron. The use of specific composition and preparation conditions (e.g., addition of a polar solvent to the organic phase), and careful election of the proper organic phase and phase fraction, enables the reproducible production of unusually small nanoparticles of less than 200 nm diameter, which can be sterile-filtered.    The particulate system produced according to the invention can be converted into a redispersible dry powder comprising nanoparticles of water-insoluble drug coated with a protein, and free protein to which molecules of the pharmacological agent are bound. This results in a unique delivery system, in which part of the pharmacologically active agent is readily bioavailable (in the form of molecules bound to the protein), and part of the agent is present within particles without any polymeric matrix therein.
Patent CA-2684893-A1 (CA)
Inventor: CONNETTI STEPHEN
IPC: G06T17/05
Filed: 2008-04-22
Abstract: A geospatial modeling system (20) may include a geospatial database (21) for storing geospatial data points each having respective elevations associated therewith. The system (20) may further include a processor (22) for data thinning the geospatial data points by selecting discriminant points therefrom. The processor (22) may select discriminant points based upon: (a) identifying a current patch having a plurality of spaced-apart current geospatial data boundary points; (b) selecting a current discriminant point within the current patch based upon sequentially stepping through the geospatial data points therein to determine respective elevation differences relative to the current geospatial boundary points and comparing the elevation differences to a threshold range; (c) identifying a plurality of new patches, each having a plurality of spaced-apart new geospatial boundary points including the current discriminant point; and (d) iteratively repeating steps (b) and (c) for each of the new patches until no further new discriminant point is selected.
Patent CA-2687014-A1 (CA)
Title: Fire retardant polystyrene
Inventor: BROUWER WILLEM DIEDERIK
IPC: C08J9/00
Filed: 2008-05-22
Abstract: A composition comprising : (i) expanded or expandable polystyrene beads or particles (ii) an intumescent, and (iii) a fire-resistant binder the weight of (i) being in the range 20 - 75% by weight based on the total weight of (i), (ii) and (iii) is disclosed. The fire-resistant binder is an inorganic material chosen from the list comprising metal, silicates, metal aluminates, metal amminosilicates and zeolites preferably an aqueous solution of sodium silicate. A method of preparing a fire-retardant polystyrene is also disclosed.
Patent CA-2687819-A1 (CA)
Inventor: HASMANN MAX
IPC: A61K49/00
Filed: 2008-06-04
Abstract: This invention relates to a composition of a non-labeled monoclonal antibody binding to a tumor antigen and a second monoclonal antibody labeled with a NIR fluorescence label, binding to the same tumor antigen, wherein the first and second antibody exhibit no cross reactivity. The composition can be used for the treatment of patients suffering of solid tumors which are associated with an overexpression of such a tumor antigen. The invention further relates to a the co-administration of said first and second antibody as wells as to a method of acquiring a NIR fluorescence images of such tumors or the patients suffering from such tumors during the treatment of said patientwith such composition.
Patent CA-2688562-A1 (CA)
Inventor: KATSUNUMA ATSUSHI
IPC: G01J3/18
Filed: 2008-05-21
Abstract: A tunable filter is provided with a polarizing branch element that makes two linearly polarized light components with mutually orthogonal vibrating directions branch off from input light, a wavelength dispersion type spectroscopic element that separates two linearly polarized light components made by the polarizing branch element into two spectrum images that correspond to the two linearly polarized light components and are spatially divergent with respect to one direction, and a reflective type spatial modulation element that modulates and reflects the linearly polarized light component in each wavelength region independently of the two spectrum images with each other, wherein the modulated light component reflected from the reflective type spatial modulation element is reentered in the wavelength dispersion type spectroscopic element and the polarizing branch element, so that one output light component with a wavelength region modulated by the reflective type spatial modulation element and another output light component with a non-modulated wavelength region are separately output, and the input light and reentered light components to the polarizing branch element and the input light and reentered light components to the wavelength dispersion type spectroscopic element are parallel light fluxes.
Patent CA-2690186-A1 (CA)
Inventor: MITSUDERA HIROMASA
IPC: C07C323/03
Filed: 2008-06-26
Abstract: There is provided a halogen-containing organosulfur compound having an excellent controlling effect on arthropod pests represented by the formula (I): wherein, m represents 0, 1 or 2, n represents 0, 1 or 2, A  represents optionally substituted C3-C7 cycloalkyl or optionally substituted C5-C7 cycloalkenyl group, Q represents a C1-C5 haloalkyl group containing at least one fluorine atom, or a fluorine atom, R1 and R3 independently represent optionally substituted C1-C4 chain hydrocarbon, halogen or hydrogen, R2 and R4 independently represent optionally substituted C1-C4 chain hydrocarbon, -C(=G)R5, cyano, halogen or hydrogen, G represents oxygen or sulfur, and R5 represents optionally substituted C1-C4 alkyl, hydroxyl, optionally substituted C1-C4 alkoxy, optionally substituted C3-C6 alkenyloxy, optionally substituted C3-C6 alkynyloxy, amino, optionally substituted C1-C4 alkylamino, optionally substituted di(C1-C4 alkyl)amino, C2-C5 cyclic amino or hydrogen.
Patent CA-2690654-A1 (CA)
Inventor: LEWIS LARRY NEIL
IPC: B01J23/50
Filed: 2010-01-21
Abstract: A composition includes a templated metal oxide substrate having a plurality of pores and a catalyst material includes silver. The composition under H2 at 30 degrees Celsius, the composition at a wavelength that is in a range of from about 350 nm to about 500 nm has a VIS-UV absorbance intensity that is at least 20 percent less than a standard silver alumina catalyst (Ag STD). The standard alumina is Norton alumina, and which has the same amount of silver by weight.
Patent CA-2692607-A1 (CA)
Inventor: KNOBLOCH BENTON
IPC: E21B31/06
Filed: 2008-07-06
Abstract: Apparatus for cleaning the inner wall of well-bore tubulars, and for capturing downhole debris in the wellbore An elongated, tubular central mandrel has threaded connections on either end for makeup into a tubular string The mandrel has recesses on its outer circumference into which split rings are mounted Various service elements are then attachable to the cen-tral mandrel, by sliding them over the mandrel and holding them in place with stabilizer elements which connect to the split rings Different embodiments of the service elements include a brush assembly, a junk basket, and a magnet The stabilizer elements may be mounted onto the split rings so as to either be rotation-ally locked with respect to the mandrel, or so as to be capable of rotating with respect to the mandrel, since th service elements are held in place on the central mandrel by the stabilizer ele-ments.
Patent CA-2692996-A1 (CA)
Inventor: BRIERS JAN JOZEF MARIA
IPC: E21B43/12
Filed: 2008-08-15
Abstract: A method for controlling the influx of crude oil, natural gas and/or other effluents into inflow zones of a multizone well with distinct inflow zones through which crude oil and/or natural gas and/or other effluents are produced, which zones are each provided with an inflow control device (ICD) for controlling the fluid influx through the zone into the well comprises: a) assessing the flux of crude oil, natural gas, water and/or other effluents from the well; b) monitoring production variables, including the position of each ICD and/or the fluid pressure in each inflow zone upstream of each ICD  and/or the fluid pressure in a well tubular downstream and in the vicinity of each ICD; c) performing a well test during which production from the well is varied by sequentially adjusting the position of each of the ICD's and the flux of crude oil, natural gas and/or other well effluents is assessed in accordance with step a; d) monitoring during step c production variables in accordance with step b;  e) deriving from steps c and d a zonal production estimation model for each inflow zone of the well; and f) adjusting each ICD  to control the influx of crude oil, natural gas and/or other effluents into each inflow zone on the basis of data derived from the zonal production estimation model for each inflow zone of the well.
Patent CA-2695201-A1 (CA)
Inventor: SNEAD ROBERT
IPC: F16B21/00
Filed: 2008-08-18
Abstract: A fastener device making a single hole to attach an item, providing a bolt, a nut and a toggle having a hollow cylindrical body with opposite U-shaped openings forming an aperture to pivot the toggle into a toggle first condition with coplanar body and bolt longitudinal axis or into a toggle second condition with perpendicular body and bolt longitudinal axis.
Patent CA-2695308-A1 (CA)
Inventor: WEISSBROD PAUL A
IPC: B65H75/14
Filed: 2008-10-07
Abstract: A spool (1 ) or reel for retaining continuously wound material may include a central barrel (7) and spaced apart flange members (20) extending from the central barrel (7). The flange members (20) may incorporate a retaining member (35) comprising the curved channel (38) terminating at the first and second holes (36, 36') fashioned in an inner face (21 ) of the flange members (20). The flange members may also incorporate one or more holes (36, 36') or apertures for use with associated sen~ sors where the holes or apertures include a rim to circumference for easy detection by the associated sensors. The flange members may further comprise label plat~ forms (61 ) that securely receive labels (60) that are to be affixed to the spool or reel.     A spool (1 ) or reel for retaining continuously wound material may include a central barrel (7) and spaced apart flange members (20) extending from the central barrel (7). The flange members (20) may incorporate a retaining member (35) comprising the curved channel (38) terminating at the first and second holes (36, 36') fashioned in an inner face (21 ) of the flange members (20). The flange members may also incorporate one or more holes (36, 36') or apertures for use with associated sensors where the holes or apertures include a rim to circumference for easy detection by the associated sensors. The flange members may further comprise label platforms (61 ) that securely receive labels (60) that are to be affixed to the spool or reel.
Patent CA-2696459-A1 (CA)
Title: Method and system for optimized video coding
Inventor: YANG EN-HUI
IPC: H04N7/24
Filed: 2010-03-12
Abstract: A method and encoder for full rate-distortion optimization of video coding over four free parameters; namely, coding mode, motion vector, quantizer scaling factor, and transform domain coefficients. In all cases, the rate-distortion cost for each combination of the parameters is determined based on soft decision quantization;  specifically, a graph-based searching algorithm that reveals the optimal quantized transform domain coefficients for encoding a macroblock or sub-block of a macroblock. The full joint optimization includes a full search of the product space defined by the possible combinations of the free parameters without approximations.  Approximations and simplifications to reduce complexity are also disclosed.
Patent CA-2698790-A1 (CA)
Title: Heat treatment of thin polymer films
Inventor: PLANETA MIROSLAV
IPC: B29C61/02
Filed: 2009-08-12
Abstract: Stretch film is treated by passing a web of tackifier-containing, un-bloomed thin polymer film through a heater so that the web is heated to a tem-perature sufficient to cause tackifier bloom prior to the web reaching a next stage in an in-line process. Also, a pattern can be applied to a thin polymer film. An oriented web of thin polymer film is passed across at least one heated roller having the pattern engraved thereon to define face regions and relief regions col-lectively conforming to the pattern. As the web contacts each roller surface, por-tions of the web positioned over the relief regions receive less heat than portions of the web positioned over the face regions, thereby causing the respective portions of the web to undergo differential, heat-in-duced shrinkage which imparts the pat-tern to the thin polymer film.
Patent CA-2704284-A1 (CA)
Title: Co-crystals and pharmaceutical compositions comprising the same
Inventor: ZHANG YUEGANG
IPC: A61K31/454
Filed: 2008-08-29
Abstract: The invention relates to co-crystals and compositions each comprising VX-950 and a co-crystal former selected from the group consisting of 3-methoxy-4-hydroxybenzoic acid, 2,4-dihydroxybenzoic acid, and 2,5-dihydroxybenzoic acid. Also within the scope of this invention are methods of making and using the same.
Patent CA-2705428-A1 (CA)
Inventor: SINS VERONIQUE
IPC: B65D3/26
Filed: 2008-10-02
Abstract: A refrigerated dough container (10) that has less than 5% non-paper material by weight such that the container qualifies as being a recyclable paper article. The container includes a paperboard body ply (12) and a liner ply (30) adhered to the inner surface of the body ply. The liner ply (30) consists of a paper layer (32) having an outer surface adhered to the inner surface of the container body, and at least one non-paper layer (36,38) imparting moisture/gas barrier and sealing characteristics to the liner. The total weight of the non-paper layer (s) does not exceed 5% of the combined body ply and liner ply weight. The non-paper layers can include a metallized film or thin foil as a barrier layer and a polyolefin or sealing varnish as a sealant layer. Alternatively, a single non-paper layer, namely a PVDC layer, can be extrusion-coated onto the paper layer.
Patent CA-2706111-A1 (CA)
Inventor: OEHLBERG PETER J
IPC: A61M36/14
Filed: 2008-12-03
Abstract: A homogenous dispersion of aqueous droplets of a radiopharmaceutical or radiodiagnostic agent within a non-aqueous medium and method of making the same is provided. The homogenous dispersion is largely free of impurities and constitutes a substantially uniform distribution of sodium thiosulfate and radiopharmaceutical which is stable for a time sufficient to fill and solidify within gel capsules. In making the homogenous dispersion, dry sodium thiosulfate and dry potassium phosphate dibasic anhydrous are uniformly dispersed within non-aqueous, liquid polyethylene glycol.
Patent CA-2706329-A1 (CA)
Inventor: AMIR NADER
IPC: A61M21/00
Filed: 2008-11-17
Abstract: Systems and methods for treating patients with an anxiety disorder are disclosed. The systems comprise a screen for displaying sets of stimuli, a computer to control the display of stimuli onto the screen during at least one treatment session and the ability for the patient to interact with the screen in response to the displayed stimuli. The interaction of the patient with the system during the treatment session is capable of treating patient anxiety associated with an anxiety disorder, such as social anxiety. Also provided are computer programs capable of being used in the systems and methods of the present invention for treating anxiety.
Patent CA-2711165-A1 (CA)
Inventor: MICHELLI RICHARD D
IPC: F16K31/122
Filed: 2010-07-23
Abstract: A vacuum relief valve includes: a housing with a central cavity, the housing having a system branch, a vacuum branch, a pilot branch, and an exhaust branch, each of the branches in fluid communication with the central cavity and having a respective port; a piston assembly comprising a first disk located in the pilot branch, a second disk located adjacent the exhaust branch, and a connecting member to which the first and second disks are mounted; and an actuator attached to a pilot seal, the actuator configured to move the pilot seal between a closed position, in which the pilot seal is positioned in and seals the pilot port, and an open position, in which the pilot seal is spaced from and does not seal the pilot port. When the pilot seal is in the closed position, the second disk is positioned on and seals the exhaust port, and when the pilot seal is in the open position, the second disk is spaced from and does not seal the exhaust port. In this configuration, often a smaller, less expensive actuator may be used to actuate the valve.
Patent CA-2712925-A1 (CA)
Inventor: BAILEY ERIC DANA
IPC: G06F40/143
Filed: 2009-01-21
Abstract: Technologies are described herein for editing a document using a transitory editing surface. A word processing program displays a document in a window. Upon detection of the placement of an insertion pointer within a paragraph of text in the document, an editing surface is created overlaying the paragraph in the window and containing the contents of the underlying paragraph. User input is monitored by the word processing program while the editing of the contents is processed by the editing surface. When editing is complete, the modified contents of the editing surface are copied into the document and the editing surface is destroyed.
Patent CA-2714866-A1 (CA)
Inventor: CATHCART ALLAN K
IPC: B60N2/90
Filed: 2005-05-10
Abstract: L'invention concerne un moule, plus particulièrement un moule permettant de produire des articles en mousse. Selon le meilleur mode de réalisation, le moule comprend un couvercle et un bol pouvant être entraîné de façon amovible afin de définir une cavité de moule. Ledit couvercle comprend ceci : i) un évent doté d'un passage permettant au gaz de s'échapper de la cavité de moule et ii) plusieurs rainures raccordées à l'évent. L'utilisation de plusieurs rainures ou fentes dans la surface de la cavité de moule agit efficacement à titre de siphon pour éloigner le gaz de la composition à mouler. Les rainures ou fentes sont raccordées à un ou plusieurs évents, qui permettent ensuite l'échappement du gaz de la cavité de moule vers l'extérieur du moule.