baber/WOPTO huggingface dataset:
Patent NZ-228722-A (NZ)
Title: Substituted indole and indazole derivatives and pharmaceutical compositions
Inventor: MATASSA VICTOR GIULIO
IPC: C07D209/00
Filed: 1989-04-12
Abstract: This invention provides a series of novel hetera-aliphatic carboxamides of formula I in which the group >Z-Y-X< is selected from >C=CH-N<, >N-CH=C<, >C=N-N< and >N-N=C< and the other radicals have the meanings defined in the following specification. The compounds of formula I are leukotriene antagonists. The invention also provides pharmaceutically acceptable salts of the formula I compounds; pharmaceutical compositions containing the formula I compound, or their salts, for use in the treatment of, for example, allergic or inflammatory diseases, or endotoxic or traumatic shock conditions; and processes for the manufacture of the formula I compounds, as well as intermediates for use in such manufacture.
Patent NZ-231376-A (NZ)
Title: Hydroxy-1,2,3,4-tetrahydroaminoacridine derivatives, preparation and pharmaceutical compositions thereof
Inventor: SHUTSKE GREGORY MICHAEL
IPC: C07D219/12
Filed: 1989-11-14
Abstract: There are disclosed compounds having the formula I <CHEM>  where  n is 1 or 2; X is hydrogen, loweralkyl, loweralkoxy, halogen, hydroxy, nitro or trifluoromethyl; R is hydrogen, benzyl or alkanoyl of 2- 12 carbons, with the proviso that the group -OR may not be on the 1-position of the three ring system; and R1 and R2 are each independently hydrogen, loweralkyl or arylloweralkyl, but both may not be arylloweralkyl simultaneously, or alternatively R1 and R2 taken together may constitute the group @@NR3R4 where R3 and R4 are each independently loweralkyl;  and a process for their preparation. The compounds can be used for the treatment of various memory dysfunctions characterized by decreased cholinergic function, such as Alzheimer's disease.
Patent NZ-233292-A (NZ)
Title: Amino pyrimidine derivatives and pharmaceutical compositions
Inventor: HARGREAVES RODNEY BRIAN
IPC: C07D409/12
Filed: 1990-04-11
Abstract: This invention concerns novel aminopyrimidinium salts of the formula I:  <IMAGE>  in which R1 is alkyl, alkenyl, cycloalkyl, phenyl, phenylalkyl or cycloalkyl-alkyl; one of R2 and R6 is a basic group selected from amino, alkylamino, dialkylamino of up to eight carbon atoms, pyrrolidino, piperidino and morpholino; and the other of R2 and R6 is hydrogen, alkyl, alkenyl, alkoxyalkyl, phenyl, phenylalkyl, cycloalkyl or cycloalkyl-alkyl; or both of R2 and R6 are basic groups as mentioned above; and R5 is hydrogen, (1-4C)alkyl or (3-6C)alkenyl; or R2 is a basic group as mentioned above, and R5 and R6 together form alkylene or, together with the appendant carbon atoms of the pyrimidine ring, complete a benzene ring; R4 is hydrogen, alkyl, cycloalkyl-alkyl, alkenyl, alkynyl or phenylalkyl; or R4 is an optionally substitutued alkylene or alkenylene linked to the nitrogen atom of the group Q.A.N-, either of which linking groups may thereby completing a ring including two adjacent carbon atoms of Q, the carbon atoms of A and the adjacent nitrogen atom of the group -A.N-; A is a direct bond to the the group -N(R4)- or is alkylene or oxyalkylene; Q is a pyridyl, furyl, thienyl or phenyl moiety; and Y is a physiologically acceptable anion; but excluding a number of compounds specified hereinafter. The invention also includes certain closely related anhydro-base derivatives which, like the formula I compounds, possess beneficial effects on the cardiovascular system (and in particular beneficial effects modulated via the sino-atrial node). Also included are pharmaceutical compositions containing the formula I compound (or a related anhydro-base) as active ingredient, and processes for the manufacture of the various novel compounds.
Patent NZ-238754-A (NZ)
Title: Coated spheres prepared by granulation
Inventor: WEINHOLD STEPHEN
IPC: A23K1/00
Filed: 1991-06-27
Abstract: The invention relates to new granules as well as to a process for their preparation, the granules being obtained by extrusion of a mixture containing a fusible binding agent in an amount such that it enables the mixture to pass through a die. The granules obtained are then coated with a polymer which enables them to pass through the rumen without degradation. 
<??>These granules after coating are used in animal feeds for ruminants.
Patent NZ-241613-A (NZ)
Title: Highlighting intagliations in tablets
Inventor: GILIS PAUL MARIE VICTOR
IPC: A61J3/06
Filed: 1992-02-13
Abstract: A method of highlighting intagliations in white or colored coated tablets by spraying onto said tablets a suspension comprising a filling material having a different color, a waxy material and a solvent, and removing the solvent and the excess of filling material and waxy material.
Patent NZ-243705-A (NZ)
Title: Coating compositions containing phosphate, zinc, nickel and manganese ions, for coating metal surfaces; phosphating process
Inventor: SIENKOWSKI MICHAEL L
IPC: C23C22/18
Filed: 1992-07-24
Abstract: Zinc phosphate coatings for metal surfaces and phosphating process. Concentrates containing (a) hydroxylamine sulfate and (b) zinc, nickel, manganese and phosphate ions are formulated into aqueous coating solutions for treating metal surfaces, including ferrous, zinc and aluminum surfaces.
Patent NZ-249202-A (NZ)
Title: Bicyclo[2.2.2.]octane derivatives, preparation and pharmaceutical compositions thereof
Inventor: KALINDJIAN SARKIS BARRET
IPC: C07C323/41
Filed: 1993-02-19
Abstract: Compounds of formula (I) wherein W is a carbonyl, sulphonyl or sulphinyl group, and X is a carbonyl, sulphonyl or sulphinyl group or -C(O)-CH2- (in which the carbonyl group is bonded to Y), provided that at least one of W and X contains carbonyl, Y is R7-O- or R7-N(R8)- (wherein R7 is H or C1 to C15 hydrocarbyl, up to two carbon atoms of the hydrocarbyl moiety optionally being replaced by a nitrogen, oxygen or sulphur atom provided that Y does not contain a -O-O- group, and R8 is H, C1 to C3 alkyl, carboxymethyl or esterified carboxymethyl), Z is selected from (i) -O-R9, (ii), (iii), (iv), wherein R9-R13, Q, Q', G, T, A, B, a and b are as defined in claim 1; or Z is absent and W is H, R1 is H, methyl, halo, carboxy, esterified carboxy, amidated carboxy, carboxymethyl, esterified carboxymethyl or amidated carboxymethyl, R2 is selected from the groups recited above for R1; R3 and R4 (or each R3 and R4 group, when m or n is 2 or more) are independently selected from halo, amino, nitro, cyano, sulphamoyl, C1 to C3 alkyl, C1 to C3 alkoxy, carboxy, esterified carboxy and amidated carboxy, R5 and R6 are independently selected from H and the groups recited above for R3; m, n = 0 to 4, with provisos as given in claim 1 and pharmaceutically acceptable salts thereof, are ligands at cholecystokinin and/or gastrin receptors.
Patent NZ-256006-A (NZ)
Title: An inhalation device; plurality of powder container venturi depressions individually feed to inhaler, and shape of depressions conform to shape of inhalation passage
Inventor: COX PETER ERICH
IPC: A61M15/00
Filed: 1993-09-09
Abstract: PCT No. PCT/EP93/02439 Sec. 371 Date Mar. 7, 1995 Sec. 102(e) Date Mar. 7, 1995 PCT Filed Sep. 9, 1993 PCT Pub. No. WO94/06497 PCT Pub. Date Mar. 31, 1994The invention relates to an inhalation device by which powdered material can be inhaled. A plurality of powder containers, each having a powder containing depression therein, may be individually fed to a use station which cooperates with an inhalation means. The inhalation means includes an outlet communicating with the open container by a passage, which passage has a wall means which cooperates with the powder containing depression to define a venturi.
Patent NZ-285149-A (NZ)
Title: N-morpholino-n-nitrosaminoacetonitrile cyclodextrin inclusion complexes; pharmaceutical compositions
Inventor: GECZY JOSEPH
IPC: C07D295/30
Filed: 1995-04-25
Abstract: PCT No. PCT/HU95/00011 Sec. 371 Date Apr. 16, 1996 Sec. 102(e) Date Apr. 16, 1996 PCT Filed Apr. 25, 1995 PCT Pub. No. WO95/29172 PCT Pub. Date Nov. 2, 1995New inclusion complexes which are stable in their so-lid state formed of SIN-1A and cyclodextrins or cyclodextrin derivatives and optionally also containing ions as catalyst or stabilizer. The complexes release nitric oxide at room temperature upon dissolving in water or aqueous systems. The ions are preferably carboxylic acid anions such as acetate, formiate, propionate, ascorbinate, tartarate and/or lactate and/or inorganic acid anions such as phosphate, phosphite, borate, carbonate, hydrocarbonate, sulfate, sulfite and/or cations such as alkali and/or ammonium. Pharmaceutical compositions as well as kits containing the complexes. The kits are to be used as NO-liberating standards to release NO in a predictable amount and rate on dissolving in aqueous media. Processes for the preparation of the complexes by subjecting at a suitable pH SIN-1 to the catalytic action of ions to shift the equilibrium towards formation of SIN-1A in the presence of cyclodextrins or cyclodextrin derivatives capable to form inclusion complexes, whereby the SIN-1A formed is immediately complexed and stabilized and isolating in the solid state the obtained new complexes optionally containing ions. A preferred process includes reacting SIN-1 and a cyclodextrin or cyclodextrin derivative in the solid state in the presence of a salt as a catalyst by thoroughly admixing or milling the components together or by freeze drying an aqueous, oxygen-free solution containing the components, followed preferably by "second drying" in vacuo.
Patent NZ-285848-A (NZ)
Title: Stabilised microcapsulated additives for food
Inventor: SANTUS GIANCARLO
IPC: A23L9/10
Filed: 1995-06-12
Abstract: A method to protect biactive compounds and microorganisms from inactivation in the gastric tract as well as in foods. The method involves preparation and coating of a multiplicity of microgranules containing the compounds or microorganisms. The microgranules are generally smaller than 500  mu m and have physical characteristics that permit homogeneous filming as well as ready suspension after coating in common foodstuffs such as milk and milk products and fruit juices.
Patent NZ-289697-A (NZ)
Title: Endless conveyor carton pushing lug assembly: flip-flop lugs
Inventor: DISRUD JEFF A
IPC: B65G19/02
Filed: 1995-06-12
Abstract: An overhead pusher lug assembly for stabilizing the top portions of cartons in a carton packaging machine comprises an endless chain conveyor having an array of pusher lugs rotatably mounted thereto at spaced intervals. The lugs are rotatable between a first position wherein the lugs extend upwardly from the lower flight of the conveyor and a second position wherein the lugs extend downwardly from the lower flight of the conveyor for insertion between adjacent cartons on a carton conveyor. As the pusher lugs move onto the lower flight of the conveyor, they engage the end of an elongated bar, which rotates or flips the pusher lugs into place between underlying cartons so that the lugs do not impact and disfigure trailing cartons on the carton path.
Patent NZ-314976-A (NZ)
Title: Stripping composition for paints, varnishes or lacquers comprising water and anisole
Inventor: LALLIER JEAN-PIERRE
IPC: C09D9/00
Filed: 1997-05-30
Abstract: Stripping formulations for paints, varnishes and lacquers based on the constituents anisole and water.
Patent NZ-330242-A (NZ)
Title: Interactive tv system for use with live tv broadcast, central controller has database to store known information about broadcast for transmission to players
Inventor: MCKEOWN MARK WILLIAM
IPC: H04N7/173
Filed: 1998-04-21
Abstract: An interactive, predictive game control system for use in conjunction with a live TV broadcast received by one or more remote players (C). The system comprises a central controller (1) for generating game playing data for transmission with a TV broadcast to the remote player(s) and for receiving information from the remote player(s). An input device (2) is connected to the central controller (1). A database (4A) is connected to the central controller (1) for storing data relating to the content of the live broadcast and known in advance of the live broadcast. The central controller (1) is responsive to signals from the input device (2):   a) prior to the live broadcast, to select data from the database (4A) for transmission to the remote user(s) in advance of and/or during the live broadcast, and b) during or after the live broadcast, to record the time of occurrence of one or more events relating to the live broadcast which are to be predicted by the remote player(s), as indicated by an operator to the central controller (1) via the input device (2).   <IMAGE>
Patent NZ-333858-A (NZ)
Title: Polynucleotide sequence located on the avian female specific W sex chromosome and its use in determining the sex of birds
Inventor: BINDER MICHELE DENISE
IPC: C12Q1/68
Filed: 1997-06-23
Abstract: An isolated polynucleotide that hybridizes to the avian W chromosome.  The presence of this polynucleotide in a biological sample can be used to determine the sex of a bird, preferably a bird selected from the species, Psittacines, Passerines, Penguins, Pigeons, Cranes rails and allies, chickens and kookaburras.
Patent NZ-338072-A (NZ)
Title: Electric fence erecting and dismantling apparatus for use with an ATV
Inventor: WIERZBICKI JAN HENRY
IPC: E04H17/26
Filed: 1998-04-22
Abstract: Provided is an apparatus for erecting and dismantling a temporary fence, such as an electric fence, made up of a plurality of posts (P) and fence wire (W) with the aid of an ATV (A).  The apparatus includes a drive reel mounting for supporting and driving at least one reel (10) on which fence wire (W) can be loaded.  A guide (11, 12) is provided for directing the fence wire (W) out of wire receiving element(s) (14) on each post (P) and onto the reel (10). The guide (11, 12) is arranged to apply a force to the wire (W) such as to release the wire from the wire receiving element (14) as the ATV (A) is moved relative to the post (P).  The apparatus also includes a post extractor (20) which engages with and extracts a post (P2) as the ATV (A) moves relative to the post (P2).
Patent NZ-501069-A (NZ)
Title: Monoesters of probucol for the treatment of cardiovascular and inflammatory disease
Inventor: SOMERS PATRICIA K
IPC: A01N37/02
Filed: 1998-05-14
Abstract: The specification describes the use of a nonoester of probucol or a pharmaceutically acceptable salt to inhibit VCAM-1 and therefore to treat cardiovascular and inflammatory diseases.
Patent NZ-501248-A (NZ)
Title: Pharmaceutical composition for combination of piperidinoalkanol-decongestant
Inventor: MINISH SHARON K
IPC: A61K47/04
Filed: 1998-07-21
Abstract: A pharmaceutical composition in the form of a bilayer tablet comprising: (a) a first discrete zone made with Formulation (A) which comprises a therapeutically effective decongestant amount of a sympathomimetic drug, or a pharmaceutically acceptable salt thereof, in an amount of about 18 % to about 39 % by weight of Formulation (A), and a first carrier base material, the first carrier base material comprising a mixture of: (i) carnauba wax in an amount of about 59 % to about 81 % by weight of Formulation (A); and (ii) a suitable antiadherent in an amount of about 0.25 % to about 2.00 % by weight of Formulation (A); wherein said first carrier base material provides a sustained release of the sympathomimetic drug; and (b) a second discrete zone made with Formulation (B) which comprises a therapeutically effective antihistaminic amount of a piperidinoalkanol, or a pharmaceutically acceptable salt thereof, in an amount of about 15 % to about 30 % by weight of Formulation (B) and a second carrier base material, the second carrier base comprising a mixture of: (i) a cellulose diluent in an amount of about 27 % to about 73 % by weight of Formulation (B); (ii) pregelatinized starch in an amount of about 15 % to about 30 % by weight of Formulation (B); (iii) a suitable disintegrant in an amount of about 0.25 % to about 6.00 % by weight of Formulation (B); and (iv) a suitable lubricant in an amount of about 0.25 % to about 2.00 % by weight of Formulation (B); wherein said second carrier base material provides an immediate release of the piperidinoalkanol or the pharmaceutically acceptable salt thereof.
Patent NZ-501805-A (NZ)
Title: Apertured covering sheet for an absorbent article produced by heated needles with apertures subsequently smoothed out
Inventor: THOREN AGENTA
IPC: A61F13/472
Filed: 1998-06-18
Abstract: A fluid permeable covering sheet (9)is disclosed for an absorbent article such as a diaper, a sanitary napkin, an incontinence protector or the like, wherein heated needles (4) are brought to penetrate a sheet of textile material (1) comprising at least one thermoplastic component, whereby the thermoplastic component closest to the needles (4) melts, whereafter the needles (4) are removed and the heated material (1) is passed through at least one nip of rollers (7) so that the thermoplastic component closest around the apertures is smoothed out into a substantially smooth material surface around the apertures, whereafter the thermoplastic component is brought to solidify. An apertured covering sheet (not shown) is also disclosed for an absorbent article manufactured in accordance with the method, as is an absorbent article (not shown) provided with a covering sheet manufactured in accordance with the method.
Patent NZ-505212-A (NZ)
Title: Benzoxazine compounds useful for enhancing synaptic response
Inventor: ROGERS GARY A
IPC: A61P43/00
Filed: 2000-06-16
Abstract: A benzoxazine derivative has the formula (I) wherein:  X1 and X1 are independently H, N(R3)2, OR4 or CH2OR4 or together are O(CR5)2O, O(CR5)2(CR5)2O, OCR5= CR5, N=CR6CR6=N, N=CR3NR3, =N-O-N=, =N-S-N= or OCR3=N-; Z is O, NR7 or S; each R1 is independently H, alkyl, or fluoroalkyl, each R2 is independently H, halogen, cyano, hydroxy, alkoxy, fluoroalkoxy, thiol, alkyl, fluoroalkyl, alkoxyalkyl, aryl, heteroaryl, arylalkyl, heteroarylalkyl, aryloxy, aryloxyalkyl, arylalkoxy, or heteroarylalkoxy; each R3 and R7 is independently H, alkyl, fluoroalkyl, arylalkyl or heteroarylalkyl; each R4 is independently H, alkyl, fluoroalkyl, alkoxyalkyl, arylalkyl, heteroarylalkyl or aryloxyalkyl; each R5 is H, halogen, cyano, alkyl, fluoroalkyl, alkoxyalkyl, arylalkyl, heteroarylalkyl or aryloxyalkyl; each R6 is H, cyano, hydroxy, alkoxy, alkyl, fluoroalkyl, alkoxyalkyl, arylalkyl, heteroarylalkyl, aryloxy, aryloxyalkyl, arylalkoxy, or heteroarylalkoxy; and n is 2, 3 or 4. A pharmaceutical composition thereof is useful for treating schizophrenia, schizophrenia behaviour or depression.
Patent NZ-512318-A (NZ)
Title: Breast pump
Inventor: MCKENDRY BRUCE
IPC: A01J5/00
Filed: 2001-06-12
Abstract: Breast pump apparatus 10 consists of a milk collector within manifold 26 having a vacuum path through the center of cup 28 and into collector 34 via valve 36, and back through manifold 6, and through conduits 22,24 to diaphragm pump 16. A pulsating pressure/vacuum path is also provided from the pump via flap valves 136,138, conduits 18,20, and path 62,60. Flap valves 140,142 prevent overpressure in this line.
Patent NZ-516878-A (NZ)
Title: Interactive wagering system with promotions
Inventor: MARSHALL CONNIE T
IPC: G06Q30/02
Filed: 2000-06-30
Abstract: An interactive wagering system is provided that promotes wagering to users at user equipment. The user equipment may be based on a set-top box and television, a personal computer, a cellular telephone with a display, or other such devices. Wagering may be promoted by notifying the user of an opportunity to place a wager on a given race. Wagering may also be promoted by providing the user with an on-screen opportunity to sign up for a wagering television channel or interactive wagering service. The on- screen promotions that are displayed to the user may be targeted based on the television programming that is being displayed or the user's interests. The user's activities may be monitored to collect information on the user's interests. If a particular race or the like is being discussed during a television program, the user may be provided with an opportunity to wager on that race. In this situation, racetrack, race and horse selections may be made in advance for the user.
Patent NZ-518407-A (NZ)
Title: Nucleic acids encoding membrane proteases that are expressed on endothelial cells and participate in angiogenesis and their uses
Inventor: MADISON EDWIN L
IPC: C12N5/10
Filed: 2000-11-17
Abstract: Endotheliases and portions thereof are described, particularly, the protease domains, and nucleic acids that encode the endotheliases. The endotheliases are transmembrane proteases expressed in endothelial cells. The nucleic acids and encoded proteins and protease domain portions thereof are used in a variety of prognostic, diagnostic, therapeutic and screening methods, including methods for screening for compounds that modulate angiogenesis.
Patent NZ-518605-A (NZ)
Title: Micro-cluster liquids and methods of making and using them
Inventor: HOLLOWAY WILLIAM D
IPC: C12N5/02
Filed: 2000-10-26
Abstract: A process for producing a micro-cluster liquid, which involves subjecting a liquid to cavitation so that dissolved gases in the liquid form many cavitation bubbles. The liquid containing the bubbles is then subjected to a reduced pressure. The reduction in pressure causes breakage of large liquid molecule matrices into smaller liquid molecule matrices, thereby producing a micro-cluster liquid. A composition containing a micro-cluster liquid is also claimed.
Patent NZ-523084-A (NZ)
Title: Method of making enhanced efficacy antiperspirant actives
Inventor: LEE WILSON
IPC: C01F7/00
Filed: 2001-06-19
Abstract: Disclosed herein is a wet grinding method for enhancing the antiperspirant activity of an aluminum or an aluminum/zirconium salt without the dilution and heating traditionally required wherein the enhancement is described as forming a salt wherein the amount of smaller aluminum species as represented by Peak 4 + Peak 5 is increased by an amount of at least 10% over the parent salt; and, if zirconium is present, the area of Peak 1 in the parent salt is at least 10% greater than the area of Peak 1 after grinding. An enhanced aluminum or aluminum/zirconium salt itself; and anhydrous (less than 4 % water excluding waters of hydration for the enhanced salt) antiperspirant and/or deodorant products made with the salts are also described.
Patent NZ-523287-A (NZ)
Title: Base portion of a plastic container
Inventor: BOYD TIMOTHY J
IPC: B65D8/12
Filed: 2001-06-29
Abstract: A plastic container (10) for receiving a commodity and retaining the commodity during high-temperature pasteurization and subsequent cooling that includes an upper portion (12), a sidewall portion (14), and a base portion (16). The upper portion (12) defines an aperture (22) and is sealable with a closure. The sidewall portion (14), which defines a sidewall diameter (D1), is connected to and extends generally downward from the upper portion (12). The base portion (16) has a chime section (18) connected to and extending generally downward and inward from the sidewall portion (14), and a push-up section (20) connected to and extending generally upward and inward from the chime section (18) to close the plastic container (10). The push-up section (20) defines a push-up diameter (D2), and the ratio of the sidewall diameter (D1) to the push-up diameter (D2) is at least 1.3:1.0.
Patent NZ-523459-A (NZ)
Title: Method for producing lactic acid
Inventor: NORDDAHL BIRGIR
IPC: B01D61/58
Filed: 2001-05-30
Abstract: A method for producing lactic acid, comprising producing lactic acid from a sugar-containing fermentation liquid in a fermentor by means of lactic acid-forming bacteria to result in a lactate salt, and isolating lactic acid by subjecting the fermented fermentation liquid to an ultrafiltration step to result in a substantially polymer-free permeate comprising at least one lactate salt, acidifying the permeate to a pH value of below about 3.9, and performing at least one additional isolation step in which the acidified permeate is subjected to a nanofiltration step and/or a reverse osmosis.