baber/WOPTO huggingface dataset:
Patent JP-2005172823-A (JP)
Title: Method for operating counting type radiation detector, counting type radiation detector, and x-ray apparatus
Inventor: HEISMANN BJOERN
IPC: G21K1/12
Filed: 2004-12-06
Abstract: <P>PROBLEM TO BE SOLVED: To improve linearity of a counting type radiation detector, at particularly high radiation intensity.  <P>SOLUTION: In the operating method for the counting type radiation detector having the linearity, which supplies a count pulse having a count rate dependent on the number of incident radiation quanta per unit time while respective detector elements of the counting type radiation detector operate, the count rate supplied from each detector element or a partial section of the detector elements is converted into the actual count rate through a functional relationship, or is predefined for each detector element or the partial section of detector elements, depending on the magnitude of the count rate, and is multiplied by a correction coefficient for correcting the count rate deflection generated by a dead time of the detector element, from the actual number of the incident radiation quanta per unit time.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-2006160843-A (JP)
Title: Manufacturing method of olefin copolymer
Inventor: HINO TAKAHIRO
IPC: C08F220/00
Filed: 2004-12-06
Abstract: <P>PROBLEM TO BE SOLVED: To provide a method for manufacturing a copolymer of a non-polar α-olefin with a polar olefin in the presence of a specific radical polymerization initiator.  <P>SOLUTION: The method for manufacturing the copolymer comprises polymerizing a 2-20C non-polar α-olefin with a 3-20C polar olefin in the presence of a radical polymerization initiator comprised of a cobaltocene compound represented by formula (1) and an organic halide. In the formula, R<SP>1</SP>, R<SP>2</SP>, R<SP>3</SP>, R<SP>4</SP>and R<SP>5</SP>are each independently a hydrogen atom, an optionally substituted 1-10C alkyl group, an optionally substituted 7-20C aralkyl group, an optionally substituted 6-20C aryl group, an optionally substituted 1-20C alkoxy group or the like.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006028473-A (JP)
Title: Organic/inorganic composite, its manufacturing method, and semiconductor device using the same
Inventor: MASAKADO AKIRO
IPC: H01L21/312
Filed: 2004-12-07
Abstract: <P>PROBLEM TO BE SOLVED: To provide an organic/inorganic composite which can form an insulating film having a low dielectric-constant, high mechanical strength and high flatness, to provide its manufacturing method, and to provide a semiconductor device using the composite.  <P>SOLUTION: The organic/inorganic composite having a crosslinked structure by metal-oxygen bonding comprises a compound expressed in general formula (1). (In the formula, M is a metal or silicon, X is an -O- bond or an OH group involved in crosslinking, R<SP>1</SP>is an 8-20C atom-containing molecular chain group, R<SP>2</SP>is either one of a methyl, ethyl, propyl or phenyl group, n1 and n2 are each either 0, 1 or 2).  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006163881-A (JP)
Title: Bus arbitration apparatus and device
Inventor: ASADA YASUNORI
IPC: G06F13/362
Filed: 2004-12-08
Abstract: <P>PROBLEM TO BE SOLVED: To suppress time lags in bus use right transitions to a plurality of devices to achieve quick data transfer.  <P>SOLUTION: A bus arbitration apparatus 1 controlling to give a use right for any one of a plurality of devices D1-D3 connected to a common bus comprises a bus master order register 11 storing the order denoting to which device among the plurality of devices D1-D3 are given use rights; and a GNT# output part 15 giving the use rights sequentially and recursively to the plurality of the devices D1-D3 in accordance with the order stored in the register 11.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2005165338-A (JP)
Title: Pattern forming method
Inventor: IGUCHI YUICHIRO
IPC: H01J11/36
Filed: 2004-12-10
Abstract: <P>PROBLEM TO BE SOLVED: To provide a pattern forming method with which patterning with a high aspect ratio and high precision can be made possible.  <P>SOLUTION: The pattern forming method includes a step of applying a photosensitive paste containing inorganic fine particles and organic components including a photosensitive compound as essential components, an exposing step, a developing step and a baking step, wherein a photosensitive paste whose total light transmittance with respect to 40 μm thickness at the exposure wavelength in the exposing step is ≥50% is used as the above photosensitive paste. Alternatively, the pattern forming method includes a step of applying a photosensitive paste containing inorganic fine particles and organic components including a photosensitive compound as essential components, an exposing step, a developing step and a baking step, wherein a photosensitive paste whose regular transmittance with respect to 40 μm thickness at the exposure wavelength in the exposing step is ≥10% is used as the above photosensitive paste.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-2006172956-A (JP)
Title: Manufacturing method of electrode material for solid polymer fuel cell and manufacturing method of electrode for solid polymer fuel cells using material
Inventor: YASUNAGA YOSHINOBU
IPC: H01M4/88
Filed: 2004-12-17
Abstract: <P>PROBLEM TO BE SOLVED: To provide a manufacturing method of a electrode material with a moisture content of cation exchange resin enhanced and with high proton conductivity, and a manufacturing method of an electrode for the solid polymer fuel cell using a solid polymer electrode material obtained by the method, in the electrode material for the solid polymer fuel cell containing cation exchange resin, carbon, and catalyst metal.  <P>SOLUTION: The manufacturing method of the electrode material for the solid polymer fuel cell containing the cation exchange resin, the carbon, and the catalyst metal goes through a first process of making a mixture body containing the cation exchange resin and the carbon, a second process of having the mixture body absorb catalyst material compound, and a third process of reducing the catalyst material compound in the mixture body obtained in the absorbing process. It also goes through a fourth process of dipping the electrode material for the solid polymer fuel cell obtained in the third process in power water at 100°C or higher and 200°C or lower.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006167252-A (JP)
Title: Relaxation wheelchair with function for supporting standing up electrically
Inventor: MUTSURO TAKASHI
IPC: A61G5/00
Filed: 2004-12-17
Abstract: <P>PROBLEM TO BE SOLVED: To provide an electrically stand-up supporting machine for a wheel chair, by which a user can easily get in and out from the wheel chair in the case of getting in and out from the front side of the wheelchair and which can be tilted or reclined simply, and to provide a wheelchair to which the electrically stand-up supporting machine for the wheelchair is mounted.  <P>SOLUTION: The electrically stand-up supporting machine 100 for the wheelchair consists of: a slide plate 11 to be fixed to a main body frame 18; a seat part seat frame 14 where a bolt is pivotally fitted to the slide part 11(a) of the slide plate 11 with a nut in a slidable manner to make the bolt move a seat part vertically; a slide arm 15 for moving a footrest vertically; and a driving part 12 where a cylinder rod 13 for sliding the bolt pivotally fitted to the slide part of the slide plate in a slidable manner is pivotally fitted to the bolt in a turnable manner to extend and reduce the cylinder rod 13. The foot rest, the seat part and a backrest are moved with their angles linked with each other.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006176991-A (JP)
Title: Warm-water washing toilet seat device
Inventor: TANIGAWA MASAYOSHI
IPC: E03D9/08
Filed: 2004-12-21
Abstract: <P>PROBLEM TO BE SOLVED: To impart a feeling of warmness to a region, exposed inside a toilet stool, of a user sitting on a toilet seat.  <P>SOLUTION: This warm-water washing toilet seat device comprises: the toilet seat which is placed on the toilet stool and kept at a predetermined temperature; a seating detection means for detecting that the user sits on the toilet seat; a washing means for washing private parts of the user; and a warm-air supply means for emitting warm air from a nozzle which is elongated in the internal space of the toilet stool. In the warm-water washing toilet seat device which makes the warm air emitted to dry the private parts of the user after washing, the warm-air supply means emits the warm air from the nozzle even in a predetermined case except a drying case.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006177467-A (JP)
Title: Rolling bearing and spindle device
Inventor: KANEDA HIDEKI
IPC: F16C33/58
Filed: 2004-12-24
Abstract: <P>PROBLEM TO BE SOLVED: To provide a rolling bearing enabling the safe supply of a lubricant applied onto a DLC coated surface and a spindle device having the rolling bearing.  <P>SOLUTION: DLC coatings 10 and 15 are applied onto an inner ring raceway surface 31 and an outer ring raceway surface 41 in contact with rolling elements 2 when an angular ball bearing 1 is rotated, oil sumps 20 and 25 are formed near the contact running faces 32 and 42 thereof, and grease is applied thereto. When the bearing 1, a bearing without DLC coating, and the bearing having the inner ring raceway surface and the outer ring raceways surface coated with the DLC coating are rotated 10,000, 15,000, 20,000, and 22,000 turns per minute and the raised temperature of the outer ring after the rotation is measured, the temperature of the angular ball bearing 1 is lowest. Since the grease held in the oil sumps 20 and 25 is supplied to contact faces 33 and 34 when the bearing is rotated, a coefficient of friction thereof is not increased, and the raised temperature of the contact faces 33 and 43 is suppressed to suppress the deterioration of the grease. Thus, the performance of the bearing 1 can be increased.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006180415-A (JP)
Title: Automatic extension number assignment system
Inventor: KAMIMURA TOMOHIKO
IPC: H04L12/70
Filed: 2004-12-24
Abstract: <P>PROBLEM TO BE SOLVED: To provide an automatic extension number assignment system in which a unique extension number can be acquired.  <P>SOLUTION: An automatic extension number assignment system of the present invention comprises an SIP server (1) and N pieces of 1st to Nth computers (6-1 to 6-N) (N is an integer of ≥1). Each of the N computers (6-1 to 6-N) is capable of using an IP phone, holds a different original ID and transmits an assignment request including the original ID to the SIP server (1). If N assignment requests are transmitted in the order from 1st one to Nth one, the SIP server (1) assigns N different extension numbers to the original IDs included in the N assignment requests in the order from 1st one to Nth one. The SIP server (1) registers the N original IDs and the N extension numbers on a database for assignment, refers to the database for assignment and notifies the N computers of extension number responses including the N extension numbers.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2005168038-A (JP)
Title: Mobile electronic device
Inventor: MORI AKITOSHI
IPC: H04W88/02
Filed: 2004-12-24
Abstract: <P>PROBLEM TO BE SOLVED: To provide a mobile electronic device which can change a display direction adjusting to the angle, even if the relative angle of a first case and a second case is changed, depending on the way of holding the device or its use, and secure proper operability regardless of relative locations of the first and the second cases.  <P>SOLUTION: The first case 10, having a telephone receiving part and a main display part 11 and the second case 20, having a telephone transmitting part of the mobile electronic device, are interconnected by a hinge. The cases are made turnable about the axis of rotation 2 being nearly vertical to the surface of the telephone-receiving part or the telephone transmitting part. When the first case 10 is rotated from an opened or a closed state of the device, depending on the rotation angle and the holding angle of the device, the display direction of the main display part 11 on the first case 10 can be changed.  <P>COPYRIGHT: (C)2005,JPO&NCIPI
Patent JP-2006183155-A (JP)
Title: Fiber assembly and method for producing the same
Inventor: HAZAMA REIICHI
IPC: D07B5/00
Filed: 2004-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To obtain a lightweight fiber assembly scarcely causing plastic deformation, having strong flexural strength and free from rusting by only carrying out bundling/heating treatment of fibers.  <P>SOLUTION: The fiber assembly is composed of two-component polymers having ≥10°C difference of melting temperatures. In the fiber assembly, a conjugate fiber A having a structure in which the mass ratio [(polymer AH)/(polymer AL)] of a polymer AH having higher melting point to a polymer AL having lower melting point is (50/50) to (90/10) and at least a part of the polymer AL is exposed on the surface of fiber and a fiber B composed of a polymer B having a melting point higher by ≥10°C than that of the polymer AL having lower melting point in the conjugate fiber A are gathered and bundled in the longitudinal direction of the fiber and integrated by melting of the polymer AL.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006182376-A (JP)
Title: Processed paper for paper container, blank, carton, and method for manufacturing processed paper for paper container
Inventor: WADA ATSUO
IPC: B65D5/56
Filed: 2004-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To provide a processed paper for a paper container, a blank and a carton, wherein adhesion of paste coating of a sack affixing and hot-melt affixing due to oil resistance on a surface of the paper container with oil resistance working is sufficiently secured, the processing properties are excellent, no dew condensation occurs even when performing chilled operation and refrigerated storage only by providing an oil-resistant layer for the paper container, the blank and the carton for selling and storing oily foods such as just-baked pizza, fried chicken and fried potato, and oil-stuck industrial products, and an oil-resistant layer can be provided in a case of chilled applications, and also to provide a method for manufacturing the processed paper for the paper container.  <P>SOLUTION: The processed paper for the paper container has an oil-resistant layer 3 on the surface of the base material with the Steckiht size degree of ≥500 seconds. The oil-resistant layer comprises a non-fluorine-based oil-resistant agent, and formed in a pattern, and an adhesive coating area is excluded from the pattern. The blank is punched in a predetermined shape by using the processed paper for the paper container. In addition, the blank is assembled to obtain the carton.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006182492-A (JP)
Title: Device for aligning hat-shaped plug
Inventor: KIDOKORO NOBUYOSHI
IPC: B65G47/28
Filed: 2004-12-27
Abstract: <P>PROBLEM TO BE SOLVED: To direct a hat-shaped plug facing to an arbitrary direction into a target direction.  <P>SOLUTION: This device 100 for aligning hat-shaped plug is provided with a screw conveyor 20 for conveying a hat-shaped plug, a first engaging part 35 constituted to engage a crown part of a hat-shaped plug 10A facing a first direction among the hat-shaped plugs 10 conveyed by the screw conveyor 20, and a second engaging part 55 constituted to engage a crown part of a hat-shaped plug 10B facing a second direction. The crown part of the hat-shaped plug 10A facing the first direction is engaged with the first engaging part 35 to rotate hat-shaped the plug 10A, and the crown part of the hat-shaped plug 10B facing the second direction is engaged with the second engaging part 55 to rotate the hat-shaped plug 10B so that the hat-shaped plugs 10A, 10B which do not face to a target direction face to the target direction.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006185271-A (JP)
Title: Image processing apparatus, image processing method, program and recording medium
Inventor: YOSHIKAWA TADATAKA
IPC: G06T7/60
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide an image processing apparatus, an image processing method detecting individual objects with good precision and with ease when two or more objects exist in an image, a program and a recording medium thereof.  <P>SOLUTION: The image forming apparatus is provided with an image input part 1 to which a processing subject image is inputted, a pre-processing part 2 extracting an object region occupied by the object and an outline of the object from the processing subject image, a template storing part 3 storing beforehand the subject to be detected in a processing subject image as a template, a poll part 4 carrying out polling by using the template for the outline of the object and mask processing all the poll result except the poll result matching the object region, and an analyzing part 5 detecting the object contained in the processing subject image based on the mask processed poll result.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006122636-A (JP)
Title: Game machine and simulation game program
Inventor: AOKI HAJIME
IPC: A63F7/02
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a game machine which enables a player to understand the maximum number of rounds easily.  <P>SOLUTION: The game machine has a liquid crystal display device 21 capable of changing display states and makes a main CPU 201 of a main control circuit 200 control a specific game status which is advantageous to the player when a display result of the liquid crystal display device 21 results in a predetermined specific display mode. The main CPU 201 of the main control circuit 200 determines the maximum number of rounds in the specific game status and takes a notification mode corresponding to the determined maximum number of rounds.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006184815-A (JP)
Title: Grip belt
Inventor: ISHIBASHI HIDENORI
IPC: G03B17/56
Filed: 2004-12-28
Abstract: <P>PROBLEM TO BE SOLVED: To provide a hand strap not only used as a hand strap but also used as an original grip belt for the grip belt 16 of a video camera or the like.  <P>SOLUTION: The grip belt 16 has a strap belt 19 whose base end is fixed on equipment, and a back-of-hand pad 20 fixed at the predetermined position of the strap belt 19. At least the part of the strap belt 19 existing ahead of the back-of-hand pad 20 has structure where two belts 19a and 19b are superposed and their edges are connected, and the strap belt 19 is equipped with a 1st hook-and-loop fastener 61. Meanwhile, the back-of-hand pad 20 is equipped with a 2nd hook-and-loop fastener 65 joined to the 1st hook-and-loop fastener 65. The grip belt 16 constituted in such a way is used also as the hand strap by inserting a hand between the two belts 19a and 19b existing ahead of the back-of-hand pad 20 on the strap belt 19.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2006164206-A (JP)
Title: System for updating and referring information using instant messenger
Inventor: KOYAMA HIROYUKI
IPC: G06F13/00
Filed: 2004-12-07
Abstract: <P>PROBLEM TO BE SOLVED: To update or refer to information such as database of remote place, a Web page or an information apparatus using an instant messenger.  <P>SOLUTION: Software program or hardware which accepts updating of information and requests of reference is made to participate in an instant messenger system. A user performs updating of information and requests of reference transmitting an instant message to this software program or hardware. The software program or hardware which receives the request performs updating processing or reference processing responding to the request and notifies the user of the result by instant message as occasion demands.  <P>COPYRIGHT: (C)2006,JPO&NCIPI
Patent JP-2005524233-A (JP)
Title: シリコン・ゲルマニウム・ヘテロ接合型バイポーラ・トランジスタ
IPC: H01L29/10
Filed: 2002-04-26
Abstract: 【課題】  ＳｉＧｅ  ＨＢＴの遮断周波数を高域化させる。 【解決手段】  改善されたアーリー電圧、したがって高域化された遮断周波数を有する、小信号増幅器用のバイポーラ・トランジスタを提供する。ＳｉＧｅ層（１４）は厚さが安定限界よりも厚く、Ｇｅ含有量が安定限界よりも多い。不整合転移は電荷捕獲サイトを容易に確認しうる程度には形成せず、上に存在するベース／コレクタ接合中に伸びていないから、歩留りが劣化することなく性能が向上する。
Patent JP-2005532337-A (JP)
Title: 緑内障治療のためのピラノインダゾール類およびその使用
IPC: C07D491/048
Filed: 2002-12-11
Abstract: 【課題】  ピラノインダゾール類を開示する。また、正常または上昇した眼内圧を低下および調節するための方法ならびに緑内障を治療するための方法であって、本発明の1種類またはそれ以上の化合物を含有する組成物を用いる方法を開示する。
Patent JP-2005528655-A (JP)
Title: 反射型液晶光変調器を備えた画像投射器
IPC: G02F1/13
Filed: 2003-05-19
Abstract: 反射型液晶（ＬＣ）パネル及び光学デバイスを含む光学装置。光学デバイスは、光学デバイス及び投射レンズの間に位置付けられた像平面に画像を形成する。画像は、実質的に、ザイデル収差のないものである。
Patent JP-2006500761-A (JP)
IPC: H01L41/257
Filed: 2003-06-06
Abstract: A method of producing an actuator includes shaping a block of ferroelectric material to provide an active element of the actuator. The element includes a stack of ferroelectric layers with adjacent layers separated by electrodes arranged parallel to end faces of the element. The method includes applying a primary electrode to the end faces, immersing the element and the primary electrode within a dielectric fluid, applying a primary poling voltage to the primary electrode so as to polarize the element in a first polarization direction, applying a secondary external electrode to side faces of the element, and applying a secondary poling voltage to the secondary electrode to polarize alternate layers along the first polarization direction and the other layers along a second, oppositely-directed polarization axis. The method may also include applying a conductive film to the end faces and/or applying heat to help evaporate the dielectric fluid.
Patent JP-2005530446-A (JP)
Title: 音楽ビデオを索引化して要約するシステム及び方法
IPC: G10L25/57
Filed: 2003-06-10
Abstract: 音楽ビデオを索引化し、要約する、システム及び方法を開示する。ビデオ再生デバイスにおける音楽ビデオ要約コントローラは複数の音楽ビデオを有するマルチメディア・データ・ストリームを受信する。音楽ビデオ要約コントローラは：(1)音楽ビデオをセグメント化して識別し；(2)音楽ビデオ毎に音楽ビデオ要約ファイルを生成する。音楽ビデオ要約ファイルは歌の題名及びアーティストの名前などの情報を有する。音楽ビデオ要約ファイルは更に、歌を識別する、オーディオ・セグメント及びビデオ・セグメントを有する。ユーザは音楽ビデオ要約ファイルの一覧をアクセスし、ビデオ再生デバイス上で再生する音楽ビデオを、その相当する音楽ビデオ要約ファイルを選定することによって、選定する。
Patent JP-2005531312-A (JP)
IPC: A24B3/18
Filed: 2003-06-30
Abstract: The invention relates to a process for enhancing the filling capacity of tobacco, such as cut tobacco leaf or tobacco midribs, or tobacco additional material, by treating the tobacco material having an initial moisture of 10-30% with a treatment gas consisting of nitrogen and/or argon at pressures of 400 to 1,000 bar followed by a continuous decompression and subsequent thermal post-treatment of the discharged tobacco material. The filling density of the tobacco charge in the autoclave is greater than 0.2 kg/dm<SUP>3</SUP>.
Patent JP-2005531741-A (JP)
Title: 強化吸熱関係に配されたブリッジワイヤを備えたイニシエータ
IPC: F42B3/12
Filed: 2003-06-26
Abstract: 圧密化力の必要性無しに、隣接する点火薬および／またはヘッダガラス表面と強化吸熱関係に配されたブリッジワイヤを備えるパイロテクニック・イニシエータ。
Patent JP-2005532571-A (JP)
Title: Ｐｅｔスキャナーの空間的解像度を増加させる方法および装置
IPC: G01T1/161
Filed: 2003-07-03
Abstract: 陽電子射出断層撮影法スキャナーの解像度を増加させる方法および装置。該方法および装置は、第２の検出器アレイよりも、第１検出器アレイに少なくとも約１０パーセント近い第１および第２の検出器アレイの間の地点に、対象の関心のある領域を置くための要素および行為を含む。
Patent JP-2005535993-A (JP)
Title: 臨時欠陥管理情報領域と欠陥管理領域とが設けられたディスク、その欠陥管理方法及び装置
IPC: G11B20/10
Filed: 2003-08-11
Abstract: 臨時欠陥管理情報領域とＤＭＡとが設けられたディスク、その欠陥管理方法及び装置を提供する。リードイン領域、リードアウト領域及び外側領域のうち、少なくとも一つに設けられたＤＭＡと、データ領域に設けられて臨時欠陥情報が記録される臨時欠陥情報領域と、前記リードイン領域及び前記リードアウト領域のうち、少なくとも一つに設けられた臨時欠陥管理情報領域とを含むことを特徴とするディスク。これにより、記録可能ディスク、特に、追記型ディスクに適しており、記録容量の制限があるＤＭＡを効率的に使用できる。
Patent JP-2005536601-A (JP)
Title: 導電性表面または半導性表面に対してポリマー表面を結合させるための方法ならびにその応用
IPC: C09D5/44
Filed: 2003-08-25
Abstract: 本発明は、  導電性表面または半導電性表面に対してポリマー表面を結合させるための方法に関するものである。この方法においては、ａ）導電性表面または半導電性表面上に、有機物フィルムを電気的に懸架し、ｂ）このようにして電気懸架された導電性表面または半導電性表面に対して、ポリマー表面を結合させる、ことを特徴としている。本発明は、また、この方法の応用に関するものであり、さらに、本発明を実施することによって得られた構造に関するものである。
Patent JP-2006511472-A (JP)
Title: 蛋白質の製造
IPC: A61K41/00
Filed: 2003-08-14
Abstract: 蛋白質は遺伝子工学的に加工された微生物によって製造され、その蛋白質は封入体（ＩＢ）の形状に蓄積される。封入体の蛋白質は不溶性及び不活性形状にある。それらは可溶化剤（１８）を用いて溶解させることができ、得られた溶液を希釈することで、蛋白質は活性形状に再び折り畳む。この蛋白質の再折り畳みは、蛋白質が変性しない十分弱い強度の音波（２５）を、蛋白質の溶液又は懸濁液に当てることで強められる。その強度は１０〜１００mW/cm 2 の間にすることができる。