baber/WOPTO huggingface dataset:
Patent DE-50213854-D1 (DE)
Inventor: HECKER MARKUS
IPC: A61K38/00
Filed: 2002-10-02
Granted: 2009-10-29
Abstract: Decoy oligonucleotides (I) having any of the 39 nucleotide sequences defined in the specification. An independent claim is also included for three antisense molecules (II) selected from S1, S2, and S3. TACCACTGAGACATCCTGCCAC (S1); AACATCATTGGCACGCAG (S2); GTGAACCTGCTCCAG (S3). ACTIVITY : Vasotropic; Immunosuppressive; Antidiabetic; Neuroprotective; Antiallergic; Antirheumatic; Antiinflammatory; Dermatological; Antiarthritic; Antiasthmatic; Antipsoriatic; Antibacterial. Guinea pigs were sensitized to dinitrochlorobenzene (DNCB), then treated again with DNCB to induce contact dermatitis. Intradermal injection of the STAT-1 decoy oligonucleotide (TGTGAATTACCGGAAGTG) 1 hour before final exposure to DNCB caused a significant reduction in edema, the number of apoptotic cells and leucocyte infiltration, i.e. significant suppression of the inflammatory response. MECHANISM OF ACTION : Neutralization, or inhibiting expression of, STAT-1, and thus of a range of potentially proinflammatory gene products in leucocytes, endothelial and smooth muscle cells. Genes that have a STAT-1 binding site in their promoters include those for CD40, E-selectin, inducible nitric oxide synthase (NOS), interleukin-12 and interferon-gamma . Also (I) may lift inhibition of gene expression where this is blocked by transcription factors, e.g. the gene for endothelial NOS which is down regulated by interferon-gamma .
Patent DE-50300056-D1 (DE)
Inventor: NEUHAEUSER TORSTEN
IPC: G01D11/30
Filed: 2003-03-05
Granted: 2004-09-23
Abstract: The operating position of a piston within a hydraulic or pneumatic system is detected by magnetic field sensor. The magnetic sensor (1) fits within a U-shaped retaining profile. The sensor has a convex-headed screw (3) acting on an expansion-cam within the sensor (1).
Patent DE-50306647-D1 (DE)
Inventor: KLAUS AXEL UWE
IPC: B31B50/59
Filed: 2003-11-25
Granted: 2007-04-12
Abstract: The transport container (1), in particular, for damp or wetting materials comprises a box-like container (2) with a foldable plastic shell (3) which serves as a container bottom (5), and is attached to the outside of the container side walls (4).  An Independent claim is also included for a method for producing the proposed transport container.
Patent DE-50309498-D1 (DE)
Inventor: SCHAEFER KARL ROBERT
IPC: B41F13/22
Filed: 2003-10-23
Granted: 2008-05-08
Abstract: The method involves pushing or applying a tubular or shell-shaped outer body (38) with at least one flow channel incision for a heat-carrying medium onto or to the surface of a base body (28) and pushing or applying a tubular or shell-shaped cover (36) that covers the flow channel onto or to the outer body. The outer body is fixed to the surface of the base body and the cover is attached at least to the outer body.  AN Independent claim is also included for the following:  (a)  a rotation body manufactured in accordance with the inventive method.
Patent DE-50310707-D1 (DE)
Inventor: EISENEGGER KILIAN
IPC: G04B19/247
Filed: 2003-09-11
Granted: 2008-12-11
Abstract: The display is designed to show the month number. The program wheels and discs (3, 4, 9, 6) associated with the units and tens, are designed to step or pause in increments of one month for this purpose.
Patent DE-58907303-D1 (DE)
Inventor: KRAUS MICHAEL
IPC: C12N9/74
Filed: 1989-12-07
Granted: 1994-04-28
Abstract: The process for isolating thrombin from factor II-containing solutions, such as plasma, plasma fractions or culture media of cells synthesising factor II, entails adsorption of the factor II on a solid support with less affinity for thrombin than for factor II, activation of factor II on the matrix to thrombin and elution thereof. Particularly suitable solid supports are selected copolymers, and the activation is preferably carried out with calcium ions.
Patent DE-59001923-D1 (DE)
Inventor: SCHUELEIN ROLF GUENTER
IPC: A47L13/144
Filed: 1990-05-22
Granted: 1993-08-12
Abstract: A wiping mop with a handle (1), a wiping head (4) and a press device (3) which is arranged behind the wiping head (4), and comprises a box-shaped case (14), a squeezing roller (23) carried in angled guides (22) and running from the outside towards the inside, and opposing guide rollers (20), the damp wiping cloth being squeezed out by pulling it into the case. 
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Patent DE-59002760-D1 (DE)
Inventor: KOHNERT ULRICH DR RER NAT
IPC: A61K47/00
Filed: 1990-12-19
Granted: 1993-10-21
Abstract: PCT No. PCT/EP90/02250 Sec. 371 Date Aug. 2, 1991 Sec. 102(e) Date Aug. 2, 1991 PCT Filed Dec. 19, 1990 PCT Pub. No. WO91/08765 PCT Pub. Date Jun. 27, 1991.Stabilized compositions containing a non-glycosylated human tissue type plasminogen activator derivative are disclosed. The derivative is referred to as K2P pro. The composition has enzymatic activity of at least 1.1 mU/ml, a pH of from 4.5 to 6.5, and contains citrate as well as at least one of a variety of different compounds.
Patent DE-59003822-D1 (DE)
Inventor: FUCHS ANDREAS DR
IPC: H02M5/45
Filed: 1990-02-07
Granted: 1994-01-27
Abstract: The invention relates to a supply circuit (16) for a multi-system locomotive, the supply circuit (16) containing a first and second power converter (18, 20) which are each connected in electrically conductive fashion to a first and second inverter (6, 8) by means of a first and second intermediate circuit capacitor (10, 12). According to the invention the AC-side terminals (22, 28) of the first bridge branches (24, 30) and the AC-side terminals (32, 38) of the second bridge terminals (34, 40) of the two power converters (18, 20) are connected to one another by means of inductors (26, 36), the power converter valves (V13, V14) of the second bridge branch of the first power converter (18) and the power converter valves (V21, V22) of the first bridge branch (30) of the second power converter (20) being drivable by means of a control circuit (52) which generates control signals as a function of a DC input voltage (UE) and an intermediate circuit reference voltage (UKsoll), whereas the other power converter valves (V11, V12, V23, V24) of the two power converters (18, 20) can be driven in clocked fashion by means of a further control circuit (58). In this way, a supply circuit (16) for a multi-system locomotive is obtained with which, in the case of DC voltage supply and AC voltage supply, a controlled intermediate circuit actual voltage (UK1, UK2) is obtained. <IMAGE>
Patent DE-59007997-D1 (DE)
Inventor: GRASSER GUENTER DIPL ING
IPC: G06F7/535
Filed: 1990-08-14
Granted: 1995-01-26
Abstract: A combined array for multiplication and division is built up from array cells arranged in n rows and m columns and n edge cells arranged at the edge of the array. The array cell construction corresponds to that of a division array cell. The addition of the number "0" of a row, which is necessary in a multiplication by "0", is effected by   1) switching over the multiplexer of the array cell and thus by gating out the addition and 2) gating out the overflow of the row by means of a logic circuit in the edge cell.   A multiplexer in the edge cell of each row controls the selection for multiplying or dividing and ensures that, on the one hand the multiplier or the overflow drives the multiplexer of the array cell. <IMAGE>
Patent DE-59009430-D1 (DE)
Inventor: STAIGER GERHARD DR DIPL CHEM
IPC: C07F7/12
Filed: 1990-05-31
Granted: 1995-08-31
Abstract: Organosiloxanes (1) of the general formula R14-nSi(OSiR3)n, in which R is the same or different and represents a hydrogen atom or a monovalent hydrocarbon radical having from 1 to 18 carbon atom(s) per radical or a substituted monovalent hydrocarbon radical having from 1 to 18 carbon atom(s) per radical, R1 represents R or a chlorine atom, and n is 3 or 4, are prepared by reacting organodisiloxanes (2) of the general formula (R3Si)2O, with chlorosilanes (3) of the general formula R4-nSiCln, in which R and n are the same as above, in the presence of phosphonitrile chlorides (4) and cocatalysts (5), in which the cocatalysts (5) are used concomitantly with the phosphonitrile chlorides (4) and are selected from the group consisting of amides of the general formula X-C(O)-R2, in which R2 is the same or different and represents a hydrogen atom or a monovalent hydrocarbon radical having from 1 to 8 carbon atom(s) per radical or a substituted monovalent hydrocarbon radical having from 1 to 8 carbon atom(s) per radical, and X reresents a radical of the formula R22N- or  <IMAGE>  where R2 is the same as above, R3 represents a divalent hydrocarbon radical having from 5 to 7 carbon atoms per radical, urea or urea derivatives of the general formula X-C(O)-X, where X is the same as above and cyanuric acid.
Patent DE-59302264-D1 (DE)
Inventor: KOLLMANN HARALD
IPC: F16B25/00
Filed: 1993-12-09
Granted: 1996-05-23
Abstract: Screw for forming a thread in a hole drilled in rock or concrete, characterised in that a screw thread (5, 6) has a coating (8) with settable adhesive. <IMAGE>
Patent DE-59401877-D1 (DE)
Inventor: BAECHLER ANTON R
IPC: E01H5/12
Filed: 1994-05-04
Granted: 1997-04-10
Abstract: The subject of the invention is a levelling apparatus for attaching to an attachment frame (4) on the front or the rear of a self-propelled vehicle (1) for the preparation of cross-country ski runs, ski pistes or snowmobile trails and also for roughening or breaking up hard snow and layers of ice on footways, roadways or walking paths, comprising a framework construction (20) which is pivotable about a horizontal axis running transversely to the direction of travel, with a front support (29), and a cutting device (40) for cutting open and/or comminuting the covering of snow or ice, a rear support (2) for the framework construction being provided. In the case of the levelling apparatus according to the invention, the framework construction (20) is articulated on the attachment frame (4) or a transverse beam (8), in such a way that the self-propelled vehicle (1) itself forms the rear support of the framework construction (20). <IMAGE>
Patent DE-59404803-D1 (DE)
Inventor: MUELLER HANNS-PETER DR
IPC: C08L75/04
Filed: 1994-04-29
Granted: 1998-01-29
Abstract: Rigid polyurethanes are obtainable by reacting     1. Polyisocyanates with   2. a polyol mixture comprising   a) - OH-functional polyesters having a molecular weight of from 260 to 2000 based on C9-C22-fatty acids, b) - non-functional oligomeric polyolefins having a molecular weight of from 700 to 6000, and optionally c) - at least difunctional polyols having a molecular weight of from 62 to 8000, preferably from 62 to 400, which are different from component 2a),  optionally in the presence of   3. water as blowing agent and 4. auxiliaries and additives known per se in PUR chemistry.
Patent DE-59406320-D1 (DE)
Inventor: MERKEL JOSEF
IPC: E04G17/12
Filed: 1994-12-24
Granted: 1998-07-30
Abstract: A clamp (1) serves for connecting webs (2) at the edges of form panels disposed in coplanar, side-by-side relation and has for this purpose two clamping jaws (4) urging these edge webs (2) together, each clamping jaw (4) having an 10 adjusting arm (5) which is at an angle thereto and is located at the jaw-end remote from the clamping point (4a). The adjusting arms (5) in turn have points for applying an actuating or adjusting element in the form of a wedge (9), these points of application on the two adjusting arms (5) suitably being combined to form a single point for applying the wedge (9). The wedge (9) can slide along between this point of application and the edge webs (2), suitably on the abutment (12) belonging to the clamp (1), and thereby can move the point of application and accordingly the adjusting arms (5) away form the lining skin (3) and thereby close the clamping jaws (4). For reasons of space and for proper guidance a curved wedge may be provided which is movable in the plane in which the clamping jaws (4) close.
Patent DE-59406723-D1 (DE)
Inventor: SCHUETTE RUEDIGER DR
IPC: B01J2/16
Filed: 1994-10-12
Granted: 1998-09-24
Abstract: Although sodium percarbonate obtained by crystallisation processes has a high dissolving speed (rate of dissolution), it has at the same time a moderate abrasion resistance. According to the invention, the abrasion resistance can be increased by spraying the percarbonate with an aqueous sodium percarbonate solution or an aqueous hydrogen peroxide solution and an aqueous sodium percarbonate solution in a fluidised bed at a fluidised-bed temperature in the range from 40 to 95 DEG C. Sodium percarbonate prepared according to the invention and having an amount of shell (encapsulation layer) between 3 and 10% by weight has a high abrasion resistance with at the same time a high dissolving speed.
Patent DE-59500744-D1 (DE)
Inventor: BREMER KARL-FRIEDRICH DIPL ING
IPC: F16H57/02
Filed: 1995-05-26
Granted: 1997-11-06
Abstract: The lid (4) is fixed on the end edge of the casing sleeve (12). There is a sealed separating gap (9) which in the area of the gear wheel (20) splined on the output shaft (14) is offset towards the output side. The separating gap can run in part at an acute angle (alpha) inclined to the longitudinal axis (8) of the gearbox. The separating seam has an angled or curved path. In the cover is a socket (5) for the free end of the reduction gear shaft (6).
Patent DE-59503677-D1 (DE)
Inventor: KOCH VOLKER
IPC: B01D46/46
Filed: 1995-04-28
Granted: 1998-10-29
Abstract: An assembly which indicates the level of filter blockage in an internal combustion engine air filter incorporates a pressure sensor and a second sensor which measures engine speed. The novelty is that a third sensor (17) registers the engine (11) load, and that the digital outputs from the three sensors (15, 16, 17) are jointly processed in an EPROM to provide an output indication (20, 21).
Patent DE-59504076-D1 (DE)
Inventor: SYCHRA MARCEL
IPC: C09F1/04
Filed: 1995-03-30
Granted: 1998-12-03
Abstract: PCT No. PCT/AT95/00065 Sec. 371 Date Sep. 26, 1996 Sec. 102(e) Date Sep. 26, 1996 PCT Filed Mar. 30, 1995 PCT Pub. No. WO95/26936 PCT Pub. Date Oct. 12, 1996An air entraining agent based on rosin for a composition which contains cement and which is one of mortar or concrete includes at least one rosin salt which is a reaction product of materials including rosin and from 0.5 to 50 weight % of amino alcohol; and alkali which is at least one material selected from the group consisting essentially of sodium hydroxide, potassium hydroxide, and sodium carbonate, which functions at least as a pH adjusting agent and is present in amounts effective to provide a preselected alkaline pH, and which is optionally included in the materials which form said reaction product, wherein the rosin is at least one rosin selected from the group consisting essentially of gum rosin, modified gum rosin, tall oil rosin, and wood rosin, wherein the amino alcohol is at least one amino alcohol selected from the group consisting essentially of ethanol amine, diethanol amine, triethanol amine, dimethyl ethanol amine, methyl diethanol amine, tri-n-propanol amine, triisopropanol amine, isobutyl diethanol amine, and n-butyl diethanol amine, and functions to prevent ester and amide formation, and wherein the air entraining agent has a form selected from the group comprising a solid, an aqueous solution, an aqueous colloidal suspension, and an aqueous dispersion.
Patent DE-59506503-D1 (DE)
Inventor: SILL MICHAEL
IPC: E05C17/04
Filed: 1995-03-28
Granted: 1999-09-09
Abstract: The roof window has a main frame on which is fitted a pane (2) by means of a bearing. The pane is openable so far around a pivot axis that the outside (4) of the pane is accessible for its cleaning from the room side (6) and in this cleaning position the pane is fixable against the main frame by means of a bolt (7) movable by hand on the upper cross rail (8) of the pane. The bolt works in conjunction with a closure housing (10) on the longitudinal arm (11) of the main frame near its lower cross arm. The closure tongue (25) of the bolt is provided with a nose function (26) for engaging behind a rib (30) limiting the closure aperture (29) of the closure housing. <IMAGE>
Patent DE-59600774-D1 (DE)
Inventor: BINDER ALFRED
IPC: H02K5/20
Filed: 1996-12-28
Granted: 1998-12-10
Abstract: The hand-held tool has a casing (11) containing a motor (20), a transmission (30) for it and a ventilator. The ventilator sucks in cooling air through at least one induction aperture (51, 52), passes it over the motor and transmission and then ejects it. The air is ejected through at least one outlet aperture (53, 54) in the casing. The ventilator consists of at least two parts, which cool the motor and transmission separately and independently through separate air channels. The ventilator may be in the form of a double vane (41, 42).
Patent DE-59601501-D1 (DE)
Inventor: HOLZHAUER ANTON
IPC: H01R39/06
Filed: 1996-04-17
Granted: 1999-04-29
Abstract: PCT No. PCT/EP96/01607 Sec. 371 Date Oct. 21, 1997 Sec. 102(e) Date Oct. 21, 1997 PCT Filed Apr. 17, 1996 PCT Pub. No. WO96/33534 PCT Pub. Date Oct. 24, 1996A process for manufacturing collectors, in particular flat collectors for electric machines. The individual connection elements (2) are at first directly shaped by crowding in a substantially non-machined raw conductive material (1) with their final contour and size and in their final ductile state. For that purpose, a warm forming process is used. The raw material (1) is warmed before the connection elements (2) are formed so that it does not significantly consolidate while the connection elements (2) are formed by crowding, and forming is then carried out in the warm state. In addition, a pot-shaped blank (3) may be shaped, preferably in a cold forming step, for example with inner shaped anchoring elements (6) for an insulating lining. Recesses (9) may be shaped by crowding on the cylindrical envelope (4) of the pot-shaped blank (3). These recesses are associated to the segment divisions and extend almost down to the bottom (5) of the pot-shaped blank (3). In a subsequent forming step, outer anchoring elements (13) are formed on the cylindrical envelope (4), if required a central opening (14) is cut out in the bottom (5) and the previously shaped inner anchoring elements (6) are bent outwards in the radial direction.
Patent DE-59606023-D1 (DE)
Inventor: DOERNER MANFRED
IPC: C07C39/235
Filed: 1996-12-12
Granted: 2000-11-23
Abstract: Production of vitamin K1 (I) comprises oxidising an alkali metal salt of dihydrovitamin K1 with hydrogen peroxide at pH 13.7-14.3 in the presence of a ferric salt. PREFERRED PROCESS - The Na or K salt of dihydrovitamin K1 is prepared in situ by hydrolysing dihydrovitamin K1 acetate benzoate with NaOH or KOH. The reaction is effected in a 2-phase medium comprising an aqueous alcohol (especially methanol) and an immiscible organic solvent (especially petroleum ether). The ferric salt is ferric sulphate. The pH is adjusted with acetic acid.
Patent DE-59608334-D1 (DE)
Inventor: HAMMER DR
IPC: A22C13/00
Filed: 1996-03-15
Granted: 2002-01-17
Abstract: A fibre-reinforced tubular food casing based on regenerated cellulose is prepd. from a viscose soln. contg. 10-30% less than the standard amt. at a spinning speed increased by at least 25%.
Patent DE-59610215-D1 (DE)
Inventor: METZNER WOLFGANG
IPC: A24B5/00
Filed: 1996-11-15
Granted: 2003-04-17
Abstract: The method involves veins and leaf material being separated for conditioning, cutting and drying. The veins and the leaf material are then mixed for conditioning and drying together. The tobacco veins before or after the cutting and-or the leaf material, after conditioning are provided with a casing. The veins before cutting are conditioned at a humidity of approximately 24%. The conditioned veins before cutting are stored for at least 1.5 hours, approximately 2 hours, in a closed casing. The veins are cut with a cut width of approximately 0.2 mm. The cut veins are expanded.
Patent DE-59701660-D1 (DE)
Inventor: BERGMANN KONRAD
IPC: A47K3/02
Filed: 1997-07-19
Granted: 2000-06-15
Abstract: This invention concerns a bathtub with a bottom surface (2) which is longer than in standard tubs. This effect is achieved with a tub which is bounded by a bottom surface (2) containing a drain (1), two side surfaces (3), a head-end surface (4) which slopes toward the bottom surface (2), and a foot-end surface (5) which slopes toward the bottom surface (2) in the same sense as the head-end surface (4).
Patent DE-59702596-D1 (DE)
Inventor: ROSENTHAL DIETER
IPC: B23D25/12
Filed: 1997-09-06
Granted: 2000-12-14
Abstract: The shear has knife-edges on opposite drums which are moved towards each other for the cutting operation. The peripheral speeds of the drums (6,7) are accelerated to the travel speed of the strip, and a separately-controlled mechanism (8) moves one or both of them into the working position. One drum at least can be mounted on swing arms coupled to the mechanism, or can travel under the action of the latter in a linear guide (21). The mechanism can be formed by eccentrics or pressure-operated rams, and knives can be mounted on both drums.
Patent DE-59812817-D1 (DE)
Inventor: GOMBERT ANDREAS
IPC: G02B1/118
Filed: 1998-01-14
Granted: 2005-06-30
Abstract: What is described here is an antireflective coating comprising a carrier layer consisting of an optically transparent material, which, at least on one surface side, presents antireflective properties with respect the wavelengths of the radiation incident on the surface. Moreover, methods of producing the coating are described.The invention excels itself by the provision that the antireflective surface side presents a surface roughness with stochastically distributed structures-the so-called macro structures-and that the macro structures are additionally modulated with surface structures presenting a periodic sequence-the so-called micro structures-which present period or cycle lengths smaller than the wave lengths of the radiation incident on the antireflective surface.
Patent DE-59812899-D1 (DE)
Inventor: PETER DANIEL
IPC: A61M5/145
Filed: 1998-04-22
Granted: 2005-08-04
Abstract: An apparatus for administering a substance, including a housing, a piston, a container and a propelling device, the propelling device including a base element, a first shifting stage shiftable relative to the base element, and a second shifting stage shiftable relative to the base element and to the first shifting stage and slaving the first shifting stage, wherein the propelling device, container and piston are operably coupled to the housing and the first shifting stage is in contact with the piston.
Patent DE-59900577-D1 (DE)
Inventor: ARNOLD ROLF
IPC: D04B21/14
Filed: 1999-06-15
Granted: 2002-01-31
Abstract: The mat structure is made of warp-knitted material and includes worked-in pick elements which consist of elastic, loose fiber structures shaped to resemble rope. The elements are bound through radial tying into the binding elements of the warp-knitted structure at distances matching the wales or ridges in the fabric.
Patent DE-60004371-D1 (DE)
Inventor: SCHAD D
IPC: B29C45/76
Filed: 2000-05-23
Granted: 2003-09-11
Abstract: A failsafe device, or pressure relief mechanism, for a shooting pot actuator in an injection molding machine. The shooting pot actuator has a multiple pusher rods mounted on one, or more, plates. Moving the plate holding the pusher rods depresses the shooting pot injection pistons and injects molten material into a number of mold cavities. To avoid damage to the machine from the pusher rods if an injection piston seizes, a failsafe device is used to mount the pusher rods to the plates. A shearing member is interposed, or sandwiched, between first and second apertures. Typically, the shearing member is a plate that, in normal operating conditions, blocks rearward movement of the pusher rod. However, when a predetermined shear force is applied to the shear plate, the shearing member shears and the pusher rod retracts within the channel, thereby alleviating the pressure. The failsafe device can be paired with a seizure detection system, using a laser beam, that detects piston and valve gate seizure, and provides appropriate notification or control signals.