baber/WOPTO huggingface dataset:
Patent EP-3174891-A2 (EP)
Title: Forme cristalline du riboside de nicotinamide
Inventor: CARLSON ERIK C
IPC: C07H19/048
Filed: 2015-07-24
Abstract: La présente invention concerne des formes cristallines du riboside de nicotinamide, comprenant une forme I de chlorure de riboside de nicotinamide selon la formule (I). L'invention concerne également des compositions pharmaceutiques, comprenant la forme cristalline I du chlorure de riboside de nicotinamide, et des procédés de production de telles compositions pharmaceutiques. Selon d'autres aspects, la présente invention se rapporte à des procédés impliquant l'administration à un sujet de la forme cristalline I du chlorure de riboside de nicotinamide. La présente invention concerne également des procédés de préparation de la forme cristalline I du chlorure de riboside de nicotinamide. L'invention concerne encore une forme cristalline I du chlorure de riboside de nicotinamide qui est préparée selon l'un quelconque des procédés de préparation de la forme cristalline I selon l'invention.
Patent EP-3201468-A2 (EP)
Inventor: WANG SHUAI
IPC: F04B39/12
Filed: 2015-09-25
Abstract: L'invention concerne un compresseur de réfrigération et un dispositif de limitation pour le compresseur de réfrigération. Le compresseur de réfrigération comprend un boîtier supérieur et un boîtier inférieur, qui sont combinés pour former un espace de confinement; au moins un montant de guidage qui est agencé dans le boîtier inférieur et sur lequel est monté un ressort de support; un corps de pompe agencé dans l'espace de confinement et supporté par le ressort de support; et au moins un dispositif de limitation comprenant une partie de montage montée sur une paroi intérieure du boîtier inférieur; une partie étagée reliée à une extrémité supérieure de la partie de montage et faisant saillie vers une direction s'éloignant d'une paroi intérieure du boîtier par rapport à une surface de la partie de montage; une partie de limitation s'étendant de manière oblique à partir de la partie étagée jusqu'à une position au-dessus d'une partie du corps de pompe de manière à bloquer le mouvement ascendant du corps de pompe. Le dispositif de limitation comprend une partie de montage pour fixer le dispositif de limitation à une paroi intérieure du boîtier inférieur du compresseur de réfrigération; une partie étagée reliée à une extrémité supérieure de la partie de montage et faisant saillie vers un côté par rapport à une surface de la partie de montage; et une partie de limitation s'étendant depuis une partie latérale de la partie étagée et inclinée selon un angle par rapport à la partie étagée.
Patent EP-3226877-A2 (EP)
Inventor: ALLEN STEPHEN
IPC: A61K35/44
Filed: 2015-12-03
Abstract: Certain configurations are described herein of a fluid handling apparatus that comprises a projector configured to provide an image of labware onto a support. The provided image can be used to assist a user in proper placement of the labware onto the support. The system can be configured to determine if the labware has been properly placed prior to beginning any fluid handling operations.
Patent EP-3250469-A2 (EP)
Title: Verfahren zum herstellen einer verpackung
Inventor: SPECK THOMAS
IPC: B65D75/32
Filed: 2016-01-29
Abstract: Die Erfindung betrifft ein Verfahren zum Herstellen einer Verpackung für ein Lebensmittelprodukt, insbesondere für eine Schokohohlfigur, wobei zwei Teilschalen vorgesehen werden, welche je eine vorgeformte, gewölbte dünne Folie mit einem umfangsseitig abstehenden Rand aufweisen, zwischen welche ein Lebensmittelprodukt eingebracht wird, und die Teilschalen das Produkt durch Koppeln ihrer Ränder in einer Höhlung einhausen, wobei wenigstens bereichsweise zwischen den Rändern eine Siegelschicht vorgesehen ist, und die Ränder durch Siegeln und Falzen miteinander verbunden werden. Um dies Verfahren möglichst einfach und praktisch durchführen zu können und ein wirksames Verschließen der Teilschalen an den Rändern zu ermöglichen und eine äußerlich ästhetisch und gut aussehende Verpackung zu erhalten, wird vorgeschlagen, das Siegeln zusammen mit dem Falzen oder nach dem Falzen der Ränder durchzuführen. Damit lässt sich eine entsprechende Verpackung herstellen, bei der sich der gesiegelte Bereich quer über die Falzlinie erstreckt.
Patent EP-3318540-A2 (EP)
Inventor: DA SILVA SOUSA JULIANA PATRÍCIA
IPC: C04B41/83
Filed: 2016-06-29
Abstract: The present description relates to a ceramic plate coated with a polymer material doped with hollow microspheres, to the obtaining method and uses thereof, in particular in the construction field. 
     In particular, a ceramic plate with polymer coating, wherein the polymer coating comprises at least one polymer and up to 30% (m/m) of hollow glass microspheres with a size inferior to 90 microns, that allows the reduction of a cold feeling. 
     In order to improve cold feeling, the present description further relates to ceramic coating plates with printed and encapsulated heating elements interconnected between plates by means of coupling elements, in particular a ring and heating systems, use thereof, in particular in the construction field. Said coupling elements ensure an easy functionalization of ceramic plates in particular for heating purposes.
Patent EP-3229076-A2 (EP)
Inventor: SHIRAISHI NAOMASA
IPC: G02B3/00
Filed: 2004-10-26
Abstract: An illumination optical apparatus and projection exposure apparatus capable of reducing a light quantity loss when a mask is illuminated with a polarized illumination light. An illumination optical system (ILS) for illuminating a reticle (R) with an illumination light (IL) and a projection optical system (PL) for projecting the pattern image of the reticle (R) onto a wafer (W) are provided. An illumination light (IL) emitted from an exposure light source (1) in a linearly polarized state in the illumination optical system (ILS) passes through first and second birefringent members (12, 13) having different fast axis directions and is converted into a polarized state that is substantially linearly polarized in a circumferential direction with the optical axis as the center in an almost specific annular area, and them illuminates the reticle (R) under an annular illuminating condition after passing through a fly-eye lens (14).
Patent EP-3255063-A2 (EP)
Inventor: ADAMKEWICZ JOANNE I
IPC: C12N9/64
Filed: 2013-02-28
Abstract: The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), such as where the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof).
Patent EP-3254804-A2 (EP)
Inventor: BOGNER UWE
IPC: B24B9/10
Filed: 2017-06-09
Abstract: Beschrieben wird ein Verfahren und eine Vorrichtung zum Besäumen von Glastafeln (2) mit zumindest einem Schleifkopf (3), welcher einen Träger und zumindest eine an dem Träger angeordnete und relativ zu dem Träger bewegbare Motoraufnahme (10) aufweist, an welcher ein Schleifscheibenantrieb (6) und eine mit dem Schleifscheibenantrieb (6) gekoppelte Schleifscheibe (4) angeordnet sind, welche eine Schleifoberfläche (5) zum Abtragen von Glasmaterial von einem Glastafelrand (8) aufweist. Erfindungsgemäß ist vorgesehen, dass dass der Schleifkopf (3) zumindest einen elektrischen Linearmotor (12) aufweist, welcher sowohl mit dem Träger als auch mit der Motoraufnahme (10) gekoppelt ist, und dass die Motoraufnahme (10) und die daran angeordnete Schleifscheibe (4) mittels des Linearmotors (12) entlang einer quer zur Schleifoberfläche (5) der Schleifscheibe (4) verlaufenden Zustellrichtung (A) relativ zum Träger verschiebbar sind.
Patent EP-3481287-A2 (EP)
Title: Implants utilisant une rétrodiffusion ultrasonore pour détecter des conditions physiologiques
Inventor: MAHARBIZ MICHEL M
IPC: A61N1/372
Filed: 2017-07-07
Abstract: L'invention concerne un dispositif implantable comportant un capteur configuré pour détecter la quantité d'un analyte, le pH, la température, une contrainte ou la pression; et un transducteur ultrasonore d'une longueur égale ou inférieure à environ 5 mm dans sa dimension la plus longue, configuré pour recevoir un courant modulé sur la base de la quantité d'analyte, du pH, de la température ou de la pression détectés par le capteur, et pour émettre une rétrodiffusion ultrasonore sur la base du courant reçu. Le dispositif implantable peut être implanté chez un sujet, tel qu'un animal ou une plante. L'invention concerne également des systèmes qui comprennent un ou plusieurs dispositifs implantables et un dispositif d'interrogation comprenant un ou plusieurs transducteurs ultrasonores configurés pour transmettre des ondes ultrasonores en direction du ou des dispositifs implantables ou pour recevoir une rétrodiffusion ultrasonore provenant du ou des dispositifs implantables. L'invention concerne également des procédés de détection de la quantité d'un analyte, du pH, de la température, d'une contrainte ou de la pression.
Patent EP-3492417-A2 (EP)
Inventor: ZHAO CHEN QIAN
IPC: B66B7/06
Filed: 2018-11-09
Abstract: A lifting member for an elevator system includes a rope formed from plurality of load carrying fibers extending along a length of the lifting member. The plurality of load carrying fibers including a plurality of aromatic polyester based fibers. A coating layer at least partially encapsulates the rope. An elevator system includes a hoistway, an elevator car disposed in the hoistway and movable therein, and a lifting member operably connected to the elevator car to suspend and/or drive the elevator car along the hoistway. The lifting member includes a rope formed from plurality of load carrying fibers extending along a length of the lifting member. The plurality of load carrying fibers including a plurality of aromatic polyester based fibers. A coating layer at least partially encapsulates the rope.
Patent EP-3527581-A2 (EP)
Inventor: ZLOTKIN AMIR
IPC: A01N63/50
Filed: 2012-05-31
Abstract: Compositions comprising a protein or isolated peptide, and methods using the same for preventing, dispersing or detaching a biofilm, are disclosed.
Patent EP-3665197-A2 (EP)
Inventor: CHEN YVONNE M
IPC: C07K16/28
Filed: 2018-08-10
Abstract: Provided are anti-CD8 antibodies that bind human CD8 and do not stimulate or inhibit the activation of CD8+ T cells. Also provided are nucleic acids encoding such anti-CD8 antibodies, vectors comprising such nucleic acids, host cells comprising same, and methods of making such anti-CD8 antibodies. Also provided are anti-CD8 antibodies conjugated to a detectable label. Provided are methods of using such anti-CD8 antibodies to detect CD8+ T cells in a subject, monitor disease progress in a subject having cancer, and monitor treatment progress in a subject having cancer.
Patent EP-3597245-A2 (EP)
Inventor: ZIVKOVIC IVAN
IPC: A61M5/32
Filed: 2011-07-21
Abstract: Embodiments of a retractable syringe assembly are provided that include a dual syringe barrel configuration. One or more embodiments include reuse prevention features and features that prevent premature activation of the retraction mechanism. Methods for aspirating and expelling liquid from medical devices are also provided.
Patent EP-3737688-A2 (EP)
Inventor: MAUS MARCELA V
IPC: C07K14/475
Filed: 2019-01-10
Abstract: Described herein are methods for producing and utilizing T cells comprising chimeric antigen receptors (CAR) comprising two or more extracellular domains, each comprising a portion of the extracellular domain of a Tumor Necrosis Factor (TNF) superfamily receptor ligand, e.g., A PRoliferation- Inducing Ligand (APRIL). The CARs described herein are capable of targeting, e.g., B cell maturation antigen (BCMA) and/or transmembrane activator and CAML interactor (TACI). Additionally, the CAR T cells of this present invention overcome resistance to anti-BCMA targeted therapies and utilize dimerizing and trimerizing transmembrane domains for optimal function. Further, this invention is related to methods of treating cancer (e.g., multiple myeloma (MM)), plasma cell diseases or disorders, autoimmune diseases or disorders, or transplant rejection.
Patent EP-3879964-A2 (EP)
Inventor: REEVES GREGORY
IPC: A01G2/35
Filed: 2019-11-14
Abstract: The invention relates to the grafting of perennial monocots such as bananas and oil palms. Processes for the production of such plants are disclosed herein.
Patent EP-3719851-A2 (EP)
Inventor: LEE ZHI-CHENG
IPC: H01L29/78
Filed: 2020-03-12
Abstract: A semiconductor structure includes at least one stacked fin structure, a gate and a source/drain. At least one stacked fin structure is located on a substrate, wherein the stacked fin structure includes a first fin layer and a second fin layer, and a fin dielectric layer is sandwiched by the first fin layer and the second fin layer. The gate is disposed over the stacked fin structure. The source/drain is disposed directly on the substrate and directly on sidewalls of the whole stacked fin structure. The present invention provides a semiconductor process formed said semiconductor structure.
Patent EP-3748102-A2 (EP)
Inventor: ARGAMAN GIDEON
IPC: E04F13/08
Filed: 2020-06-08
Abstract: The present invention pertains to integrated machine for manufacturing anchor embedded cladding elements. Essentially, this machine comprises a cladding block manufacturing machine and anchor feeding and embedding machine, where the concrete block manufacturing machine and anchor feeding and embedding machine are configured for coordinated operation for producing anchors embedded cladding elements comprising concrete blocks and anchors embedded within said blocks. The flexibility and versatility of the machine is in determining the end location of the anchors in the final cladding elements before even manufacturing the cladding blocks. This provides greater degree of freedom, which in turn allows increasing the strength in fixing the cladding elements to a support wall on the one hand, and decreasing onsite or prefabrication workload and difficulties in the cladding process.
Patent EP-3966851-A2 (EP)
Title: Method for manufacturing a power electronic module
Inventor: KHAZAKA RABIH
IPC: H01L23/498
Filed: 2020-04-24
Abstract: The invention relates to a method for manufacturing a power electronic module (1) by means of additive manufacturing, characterized in that it comprises the steps of: - depositing a layer of an electrically conductive nanoporous material (23) on a substrate (2a, 2b) comprising an electrically insulating layer (2c) and at least one layer of conductive metal material (2d, 2c), which is called the metallized substrate (2a, 2b); - arranging an element, for example an active component such as a semiconductor power component (3), on the layer of nanoporous material (23) and sintering the layer of nanoporous material (23) so as to provide a mechanical and electrical connection between said element (3) and the metallized substrate (2a, 2b).
Patent EP-4078941-A2 (EP)
Inventor: SCHARFENBERGER CHRISTIAN
IPC: H04N5/247
Filed: 2020-12-09
Abstract: Die Erfindung bezieht sich auf ein maschinelles Lernverfahren, ein Verfahren und eine Vorrichtung zur Umwandlung von Eingangs-Bilddaten (Ini) einer Mehrzahl von Fahrzeugkameras (2-i) eines Rundumsichtsystems in optimierte Ausgabe-Bilddaten (Opti). Das Verfahren zur Umwandlung von Eingangs-Bilddaten einer Mehrzahl von Fahrzeugkameras (2-i) eines Rundumsichtsystems in optimierte Ausgabe-Bilddaten umfasst die Schritte: a) Von den Fahrzeugkameras (2-i) aufgenommene Eingangs-Bilddaten (Ini) einer aktuellen Helligkeit oder Farbverteilung werden einem trainierten künstlichen neuronalen Netzwerk (CNN1, CNN10, CNN11, CNN12) bereitgestellt, b) das trainierte künstliche neuronale Netzwerk (CNN1, CNN10, CNN11, CNN12) ist dazu konfiguriert, die Eingangs-Bilddaten (Ini) mit der aktuellen Helligkeit oder Farbverteilung in optimierte Ausgabe-Bilddaten (Opti) mit abweichender Ausgabehelligkeit oder -farbverteilung umzuwandeln, und c) das trainierte künstliche neuronale Netzwerk (CNN1, CNN10, CNN11, CNN12) ist dazu konfiguriert, die Ausgabe-Bilddaten (Opti) auszugeben.
Patent EP-3872965-A2 (EP)
Inventor: FERRARA DAVIDE
IPC: H02K21/14
Filed: 2021-02-05
Abstract: Electric machine (1) having: a shaft (2); a rotor (4) with permanent magnets that is fitted to the shaft (2); a stator (5) having a magnetic core (6) which consists of a series of laminations made of ferromagnetic material and longitudinally crossed by a plurality of stator slots (7); and a stator winding (8) having a plurality of rigid bars (9) that are inserted in corresponding stator slots (7) and that are covered, on the outside, with an insulating coating (14). The rotor (4) has a plurality of magnetic elements (22), which are arranged beside one another around the rotation axis (3) so as to form a closed ring. Each magnetic element (22) is formed by a plurality of permanent magnets (23) which are axially arranged one after the other according to a Halbach array.
Patent EP-4001273-A2 (EP)
Inventor: WANG SHAOMENG
IPC: A61P37/00
Filed: 2017-08-28
Abstract: The present disclosure provides compounds represented by Formula I:and the pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R<sup>1a</sup>, R<sup>1b</sup>, R<sup>2a</sup>, R<sup>2b</sup>, R<sup>3</sup>, R<sup>4</sup>, R<sup>5</sup>, R<sup>6</sup>, and R<sup>7</sup> are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I for use to treat a condition or disorder responsive to inhibition of ALK such as cancer.
Patent EP-4247616-A2 (EP)
Inventor: HOLST MARCO
IPC: B29C53/12
Filed: 2021-11-22
Abstract: L'invention concerne un procédé de fabrication d'une spirale tubulaire (RW) en matière plastique thermoplastique comprenant une première étape de mise en forme consistant à assurer l'extrusion d'un produit d'extrusion tubulaire (EX) par l'intermédiaire d'une fente de filière (16) annulaire d'une extrudeuse (12) ; et une deuxième étape de mise en forme succédant directement à la première étape de mise en forme et consistant à ce que le produit d'extrusion qui est tiré vers le bas à partir de la fente de filière et qui est encore apte à la déformation plastique, soit calibré dans un dispositif de formage (18) destiné à l'obtention d'une section transversale (PQ) de géométrie définie et soit soumis à un formage en spirale tubulaire, puis la spirale tubulaire est durcie avec la section transversale de géométrie déterminée. Ce procédé permet une fabrication continue de la spirale tubulaire de haute qualité, nouvelle, en termes de tolérances de dimensions et de forme au niveau de la section transversale de la spirale tubulaire. L'invention concerne également un dispositif (10) de fabrication d'une telle spirale tubulaire.
Patent EP-4192489-A2 (EP)
Inventor: KASTELEIN ROBERT
IPC: A61K39/395
Filed: 2021-08-05
Abstract: The present disclosure relates to biologically active molecules comprising a single domain antibody (sdAb) that specifically binds to the extracellular domain of IL2Rb, compositions comprising such antibodies, and methods of use thereof.
Patent EP-4171635-A2 (EP)
Title: Cancer radiosensitization by in situ formation of gold nanoparticles and/or gold nanoclusters
Inventor: SCHWARTZ-DUVAL AARON STAR
IPC: A61K41/00
Filed: 2021-08-27
Abstract: We disclose a method, comprising administering, to a patient suffering from a cancer, a composition comprising a compound containing a gold atom; and administering, to a portion of the patient's body in which the cancer is present, radiation. We also disclose a kit comprising a composition comprising a compound containing a gold atom; and instructions to perform the method.
Patent EP-4257201-A2 (EP)
Title: Systems and methods to improve organ or tissue function and organ or tissue transplant longevity
Inventor: WAGER JEFFREY D
IPC: A61P37/06
Filed: 2015-04-15
Abstract: The present invention provides for systems and methods for inhaled CO therapy to prevent, attenuate, or delay processes that accelerate the loss of organ or tissue function, thereby increasing the lifespan of transplanted organs or tissues, or slowing the decline of native organs or tissues, or delaying the need for replacement of diseased native organs with organ transplants. Such biological processes that are prevented, attenuated, or delayed include chronic persistent inflammation, fibrosis, scarring, as well as immunologic or autoimmune attack.
Patent EP-4270173-A2 (EP)
Inventor: LOPEZ MIGUEL
IPC: G06F7/58
Filed: 2019-07-05
Abstract: The invention relates to a method of transmitting an On-Off Keying, OOK, signal which comprises an ON waveform and an OFF waveform forming a pattern representing transmitted information. According to the invention the method comprises the steps of obtaining a basic baseband waveform; scrambling the basic baseband waveform by applying a first binary randomised sequence where one of the binary values cause transformation to a complex conjugate; modulating the information to be transmitted by applying the scrambled basic baseband waveform for the ON waveform and applying no waveform for the OFF waveform; and transmitting the modulated information.
Patent EP-4265420-A2 (EP)
Inventor: PRZYBYLA JAMES R
IPC: B41J2/14
Filed: 2018-07-23
Abstract: The fluid ejection device includes a plurality of nozzles and a plurality of ejection chambers that includes a respective ejection chamber fluidically coupled to a respective nozzle. A plurality of inlet passages are fluidically coupled to the ejection chambers and input fluid to the ejection chambers at a first pressure. A plurality of outlet passages are fluidically coupled to the ejection chambers and output fluid from the ejection chambers at a second pressure that is less than the first pressure. Fluid circulates through the ejection chambers based on the pressure difference between the first and second pressure. The fluid ejection device also includes at least one fluid actuator fluidically coupled to at least one ejection chamber to pump fluid through the at least one ejection chamber.
Patent EP-4286407-A2 (EP)
Title: Anti-mutated kras t cell receptors
Inventor: WANG QIONG J
IPC: C07K14/82
Filed: 2015-11-24
Abstract: Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for an HLA-A11-restricted epitope of mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) (KRAS 7-16 ), Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog (NRAS), or Harvey Rat Sarcoma Viral Oncogene Homolog (HRAS). Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal.
Patent EP-4293419-A2 (EP)
Title: Fernsteuereinrichtung für eine bewegtbildkamera und kennzeichnungsring für eine fernsteuereinrichtung
Inventor: VOSS HENDRIK
IPC: G03B7/10
Filed: 2021-05-05
Abstract: Eine Fernsteuereinrichtung zum Erzeugen von Stellsignalen für einen Objektiv-Stellmotor einer Bewegtbildkamera umfasst ein Basisteil und ein relativ zu dem Basisteil drehbares Bedienelement zum Einstellen von Steuerbefehlen für den Objektiv-Stellmotor; einen Positionsgeber zum Erfassen einer jeweiligen Drehstellung des Bedienelementes und Erzeugen entsprechender Positionssignale; eine Auswerte- und Steuereinrichtung, welche dazu ausgebildet ist, gemäß einer Zuordnungsvorschrift in Abhängigkeit von den Positionssignalen Stellsignale für den Objektiv-Stellmotor zu ermitteln; und eine Ausgabeeinrichtung zum Übermitteln der Stellsignale an die Bewegtbildkamera. Dabei entspricht die Zuordnungsvorschrift wenigstens einem mathematischen Funktionszusammenhang und die Fernsteuereinrichtung weist eine Eingabeeinrichtung auf, über welche der mathematische Funktionszusammenhang durch Benutzereingabe konfigurierbar ist. Ein Kennzeichnungsring für eine Fernsteuereinrichtung weist einen Speicher auf, in dem eine auslesbare Kodierung gespeichert ist.