baber/WOPTO huggingface dataset:
Patent IL-70228-A0 (IL)
Title: Epimeric azahomoerythromycin a derivatives
IPC: A61K31/70
Filed: 1983-11-14
Abstract: Antibacterial 4 sec -epi-9-deoxo-9a-methyl-9a-aza-9a-homo-erythromycin A, pharmaceutically-acceptable salts thereof, pharmaceutical compositions comprising antibacterially-effectife amounts thereof, a method of treatment of bacterial infections with antibacterially effective amounts thereof, and intermediates for the synthesis thereof from erythromycin A.
Patent IL-79283-A0 (IL)
Title: Method for measuring free ligands in biological fluids,and assay for measuring same
IPC: G01N33/78
Filed: 1986-06-30
Abstract: The invention provides a method for measuring the concentration of free testosterone ligand in a biological fluid in the presence of bound ligand and endogenous binding proteins, without disturbing the equilibrium between free ligand and protein-bound ligand, which method comprises   (a) incubating, in the absence of salicylate, 2,4-dinitrophenol and 8-anilino-1-naphthalenesulfonic acid, a sample of the biological fluid with (i) a ligand analog tracer which, due to its chemical structure, does not bind to some of the endogenous binding proteins but does bind to at least one other endogenous binding protein, (ii) a concentration of a specific ligand binder having an affinity constant and selectivity for the free ligand such that the equilibrium between free ligand and protein-bound ligand is not disturbed and (iii) a concentration of sulfobromophthalein (SBP) that inhibits the binding of the ligand analog tracer to said at least one other endogenous binding protein sufficient to block reaction between the ligand analog tracer and said at least one other endogenous binding protein without displacing ligand from protein-bound ligand; (b) separating the ligand analog tracer bound to the specific ligand binder from unbound tracer; and (c) determining the concentration of free ligand in said biological fluid.
Patent IL-79432-A0 (IL)
Title: Invasive microorganisms
IPC: A61K39/00
Filed: 1986-07-16
Abstract: Novel methods and microorganisms are provided, where novel genetic mammalian cell invasive capability is imparted to a microorganism by the introduction of an exogenous inv gene. The resulting organisms are then capable of binding to mammalian cells and are transferred to the cytoplasm. Other novel genetic capabilities may be imparted to the unicellular microorganism, so that the unicellular microorganism may serve as a vaccine for one or more pathogens or may introduce genetic capabilities or foreign molecules into a mammalian host cell.
Patent IL-85906-A0 (IL)
Title: Immunogenic recombinant yeast expression product and method for purifying it
IPC: C12N15/00
Filed: 1988-03-29
Abstract: Described is an immunogenic polypeptide that is a portion of the P. vivax circumsporozoite expressed by a recombinant yeast.
Patent IL-86529-A0 (IL)
Title: Dihydropyridines,their preparation and pharmaceutical compositions containing them
IPC: A61K31/52
Filed: 1988-05-27
Abstract: Compounds of the formula:- <CHEM> wherein R is phenyl or phenyl substituted by nitro, halo, C1-C4 alkyl, C1-C4 alkoxy, fluoro(C1-C4)alkoxy, aryl(C1-C4)alkoxy, C1-C4 alkylthio, C1-C4 alkylsulphonyl, hydroxy, trifluoromethyl or cyano; R<1> and R<2> are H or C1-C6 alkyl, or the two groups form a pyrrolidinyl, piperidino, morpholino, piperazinyl, N-(C1-C4 alkyl)piperazinyl or N-(C2-C4 alkanoyl)piperazinyl group; or R<2> is H or C1-C4 alkyl and R<1> is C3-C7 cycloalkyl, aryl, indanyl or heteroaryl, or a C1-C4 alkyl group substituted by C3-C7 cycloalkyl, C1-C4 alkoxycarbonyl, aryl or heteroaryl; R<3> is OH, C1-C6 alkyloxy, aryl(C1-C4 alkoxy), or NR<4>R<5> wherein each of R<4> R<5> is independently H or C1-C6 alkyl, or the two groups form a pyrrolidinyl, piperidino, morpholino, piperazinyl, or N-(C1-C4 alkyl)piperazinyl group; Y is an alkylene group of from 2 to 8 carbon atoms and X is 1-, 2- or 3-imidazopyridyl or 1-, 2- or 3-imidazopyrimidinyl optionally substituted by C1-C4 alkyl, C1-C4 alkoxy, halo, CF3 or CN; are antagonists of PAF and are useful in the treatment of allergic inflammatory and hypersecretory conditions.
Patent IL-88539-A0 (IL)
Title: Azole compounds,their preparation and their use as fungicides
IPC: A01N43/50
Filed: 1988-11-30
Abstract: The invention provides compounds of formula I <CHEM> wherein R, R1 and Az are defined in the description, the fungicidal use of such compounds, compositions for facilitating such use and the preparation of compounds of formula I.
Patent IL-88665-A0 (IL)
Title: Fluorine-containing nitroimidazole derivatives and radiosensitizer comprising the same
IPC: A61K31/415
Filed: 1988-06-09
Abstract: A 2-nitroimidazole derivative of the formula: <CHEM> wherein Rf is a fluorine-containing organic group which has at least one fluorine atom on a carbon atom which bonds to the nitrogen atom of the imidazole ring or a carbon atom which bonds to said carbon atom and a radiosensitizer comprising said nitroimidazole derivative.
Patent IL-93299-A0 (IL)
Title: Substituted n-hydroxypyrazoles and their use as fungicides
IPC: C07D231/16
Filed: 1990-02-07
Abstract: Substituted N-hydroxypyrazoles of the general formula    <IMAGE>  I where R1, R2 and R3 are identical or different and are hydrogen, alkyl, haloalkyl, cycloalkyl, alkoxycarbonyl, halogen, aryl or arylalkyl, the aromatic ring being unsubstituted or substituted, or R2 and R3 form, with the pyrazole ring, a substituted or unsubstituted aromatic or aliphatic ring, X is CH or N, and their plant-tolerated acid addition salts and metal complexes, and fungicides containing these compounds.
Patent FI-20080096-A0 (FI)
Inventor: TORVINEN TERHO
IPC: B65G/
Filed: 2008-02-12
Abstract: The invention relates to a method for manufacturing a conveyor apparatus, a conveyor screw, in which method at least one object longitudinally hollow and open in both ends is formed in order to achieve a threaded surface on the inner surface of the object and/or on the outer surface of the object. According to the method round at least one object (1,21,42,56), longitudinally hollow and open at least in one end, it is installed at least one-piece mould (2,22,41,53), which is shaped as a holding surface of a desired threaded surface and that it is led into the object (1,21,42,56) rounded by the mould (2,22,41,53) material, wherein it is created pressure, and by means of the pressure it is achieved a threaded surface (12, 13,32,44,57), which can be utilized in transportation of material from one position to each other.
Patent IL-101440-A0 (IL)
Title: Tufting carpet
IPC: A47G27/02
Filed: 1992-03-31
Abstract: The invention relates to a tufted carpet which comprises a tufting material, a pile material and a carpet backing and essentially exclusively comprises nylon 6. The use of a chemically uniform material in all components of the tufted carpet allows the entire carpet to be recycled for recovery of the monomer starting material without separation into the individual components being necessary, which has hitherto prevented the recycling of tufted carpets and has resulted in considerable waste disposal problems.
Patent IL-115550-A0 (IL)
Title: Manufacture of 4-aryl-2-perfluoroalkyl-3-oxazolin-5-one from arylglycine
IPC: C07D413/04
Filed: 1995-10-08
Abstract: There is provided an efficient single step process to produce 4-aryl-2-perfluoroalkyl-3-oxazolin-5-one from arylglycine and a perfluoroacylating agent in the presence of a phosphorous trihalide and a solvent.The oxazolinone is a key intermediate in the production of insecticidal, nematicidal and acaricidal arylpyrrole compounds.
Patent IL-122546-A0 (IL)
Title: Use of a combination of ritonavir and a drug metabolized by cytochrome p450 monooxygenase in the preparation of medicaments and pharmaceutical compositions containing the combination
IPC: A61K31/425
Filed: 1996-06-28
Abstract: There is described a combination of ritonavir or a pharmaceutically acceptable salt thereof in combination with another HIV protease inhibitor, formulated as a single or separate composition, for use in the inhibition or treatment of an HIV infection or AIDS in a human host.
Patent IL-130635-A0 (IL)
Title: Evolution of whole cells and organisms by recursive sequence recombination
IPC: C12N15/82
Filed: 1998-01-16
Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
Patent IL-136104-A0 (IL)
Title: Vector for tissue-specific replication and gene expression
IPC: C12N5/10
Filed: 1998-11-17
Abstract: The invention generally relates to cell-specific expression vectors. It particularly relates to targeted gene therapy using recombinant expression vectors and particularly adenovirus vectors. The invention specifically relates to replication-conditional expression vectors and methods for using them. Such vectors are able to selectively replicate in a target cell or tissue to provide a therapeutic benefit in a tissue from the presence of the vector per se or from one or more heterologous gene products expressed from the vector and distributed throughout the tissue. In such vectors, a gene essential for replication is placed under the control of a heterologous tissue-specific transcriptional regulatory sequence. Thus, replication is conditioned on the presence of a factor(s) that induces transcription or the absence of a factor(s) that inhibits transcription of the gene by means of the transcriptional regulatory sequence with this vector; therefore, a target tissue can be selectively treated.
Patent IL-139422-A0 (IL)
Title: Method for metal coating of substrates
IPC: H05K3/42
Filed: 1999-05-14
Abstract: A process for coating substrates having polymer surfaces with metals in the manufacturing of printed circuit boards, in particular in the manufacturing of printed circuit boards having microscopic holes and fine geometries by the application of an electroconductive polymer layer and a subsequent metallization, wherein the electroconductive polymer layer is preferably doped with a zinc-containing, colloidal palladium solution prior to the metallization step, the electroconductive polymer is poly-3,4-ethylenedioxythiophene and a contacting with a copper(II) salt solution is performed prior to the metallization.
Patent IL-139689-A0 (IL)
Title: Testosterone derivative
IPC: C07J1/00
Filed: 1999-06-14
Abstract: The invention is the novel androgen (7alpha,17beta)-7-methyl-17-[(1-oxoundecyl)oxy]estr-4en-3one (MENT undecanoate). This compound distinguishes favourably from other testosterone derivatives in that it has a good solubility in oily media. It particularly exhibits a good dissolved potency relative to testosterone. The compound is particularly suitable for administration by means of injection.
Patent IL-141878-A0 (IL)
Title: Expression vectors containing hot spot for increased recombinant protein expression in transfected cells
IPC: C12N15/09
Filed: 1999-09-07
Abstract: A specific locus (hot spot) for recombinant gene expression has been identified in the genome of Chinese hamster ovary cells. A DNA vector containing the hot spot causes high levels of recombinant gene expression following transfection and stable integration. The selection and cloning of the specific locus and the expression of recombinant genes is disclosed, as are the DNA vectors and the host cells.
Patent IL-142109-A0 (IL)
Title: Polymers of a hydrophobic nature, filled with starch complexes
IPC: C08L101/00
Filed: 1999-09-22
Abstract: Hydrophobic polymers incompatible with starch containing, as a filler, a starch complex dispersed in the polymer matrix in the form of particles with numeric mean dimension of less than 3 microns, bound to the polymer matrix by coupling agents containing groups compatible with the matrix and with the complex, in which the starch complex is characterized by second-derivative IR absorption in the region of 940-952 cm -1  are described or wherein the starch complex is bound to the polymeric matrix through reactive groups contained in the complex capable of being fixed to the polymeric matrix.  The starch complex in the case of biodegradable polymers such as the aliphatic or aliphatic aromatic polyesters is formed with complexing agents different from the polymer forming the matrix and from EVOH copolymers.
Patent IL-142437-A0 (IL)
Title: Electromagnetically stimulating cartilage tissue
IPC: A61N2/04
Filed: 1999-10-08
Abstract: The Invention relates to the use of pulsating electromagnetic signals for stimulating chondrogenesis. The invention especially relates to the use of FGF (Fibroblast Growth Factor) in combination with pulsating electromagnetic signals for stimulating cartilage and chondrogenesis.
Patent IL-146642-A0 (IL)
Title: Printed media binder
IPC: G06K17/00
Filed: 2000-05-24
Abstract: A system is provided having a sensing device for sensing coded data printed on a print media surface which is installed with a secret key and a first identifier which uniquely identifies the sensing device, a printer installed with a second identifier which uniquely identifies the printer, and a server installed with the first and second identifiers. The printer obtains the first identifier from the sensing device and communicates the first and second identifiers to the server. The server determines from the received first and second identifiers whether the sensing device should be registered with the printer and if so, authenticates the sensing device by verifying an encryption from the sensing device, using the secret key, of a challenge message. Upon successful authentication, the sensing device is registered in the server so as to be associated with the printer.
Patent IL-157531-A0 (IL)
Title: Erodible polymers for injection
IPC: A61K47/14
Filed: 2002-02-22
Abstract: A composition for administration of a beneficial agent, contains a solvent mixture including a hydrophobic solvent and a hydrophilic solvent; a bioerodible polymer; and a beneficial agent. The polymer and the beneficial agent are dissolved. The composition has a low viscosity, allowing for easy injection through standard hypodermic needles.
Patent IL-166771-A0 (IL)
Title: Method for producing ketocarotinoids in genetically modified organisms
IPC: C12N15/82
Filed: 2005-02-09
Abstract: The present invention relates to a process for preparing ketocarotenoids by cultivation of genetically modified organisms which, compared with the wild type, have a modified ketolase activity, to the genetically modified organisms, and to the use thereof as human and animal foods and for producing ketocarotenoid extracts.
Patent IL-182924-A0 (IL)
Title: Locking nail system for arthrodesis reconstruction in calcaneus fractures
Filed: 2007-05-02
Abstract: A locking nail system for arthrodesis reconstruction of calcaneus fractures that is comprised of a cylindrical nail (1), several cannulated calcaneus-talar screws (2), a guide (3), guide tubes, bit, depth gauge, cannulated screwdriver, diapason impactor, bit with limiter and reference guide-pin, the principal object of which is the reconstruction of severe comminuted fractures of the calcaneus in humans and fixation of this bone after reconstructing its principal form, to the talus, in order to attain arthrodesis or fusion with the latter.
Patent RO-127616-A0 (RO)
Title: Auditory-verbal recuperation system with adaptive simulation and reinforcement learning
Inventor: GRIGORE OVIDIU
IPC: A61F11/00
Filed: 2011-04-13
Abstract: The invention relates to an auditory-verbal recuperation system with adaptive stimulation and reinforcement learning used in the auditory-verbal recuperation process. According to the invention, the system comprises an assembly (1) acting as a processing unit (UP) and support for the adaptive model and as user-communication interface, the assembly (1) also including a touchscreen for communicating as naturally as possible with the subject, and an audio system (SA) responsible to reproduce the auditory stimuli correlated with images presented on the touchscreen, ensuring the visual and acoustical stimulation of the subject in repeated manner and adapted to the memorizing performances proven by the same on the basis of an embedded pattern
Patent RO-130057-A0 (RO)
Title: Device for quickly screwing the cap on a glass or pet container
Inventor: COCIRTA THOMAS
IPC: B67B3/20
Filed: 2014-09-29
Abstract: The invention relates to a device for quickly screwing the caps on glass or PET containers, the device being mounted on the filling equipments in the food, chemical, pharmaceutical, cosmetic fields and the like. According to the invention, the device consists of a system () for supplying the caps (), located above the working area in a recess of conjugated shape cut into a support piece (), the cap () being lowered up to the lower edge of a pair of tweezers (), by a mandrel () actuated by a pneumatic actuation system (), the tweezers () having an axial channel of cylindrical shape cut therein to guide the cap () and, at the lower side, having a series of jaws which have in the inside a shape conjugated to the shape of the cap, and, outside, a conical surface, in contact with a surface of conjugated shape cut in the inside of a screwing sleeve () where, under the action of a spring (), the jaws of the tweezers () are deformed and ensure the clamping of the cap () by the tweezers () in order to place the cap () on the neck of the container (), the assembly formed by the driving plate (), the guide rods () and the screwing head () will move on the vertical in relation to the support piece () in some axial bearings (), at the intervention of the pneumatic actuation system () on a distance established by the construction; concomitantly with the descending motion, the screwing sleeve () starts to perform a rotary motion necessary to screw the cap () onto the container, the necessary revolving couple being produced by an electric motor () and being transmitted to the screwing sleeve () by means of a gear with toothed wheels (), and, after reaching the pre-established screwing couple, the action of the electric motor stops and the pneumatic actuation system () controls the return of the screwing head assembly to the initial position.
Patent RO-130719-A0 (RO)
Title: Global automated control and distribution system for optimizing use and storage of electric energy obtained by photo-voltaic processes
Inventor: COMAN MARIUS GHIOCEL
IPC: H02J13/00
Filed: 2015-03-31
Abstract: The invention relates to a global automated control and distribution system for optimizing the use and storage of electric energy obtained by photo-voltaic processes. According to the invention, the system consists of a pre-programmed processor (1) provided with a central unit and an adequate number of inputs and outputs, a bar (17) for electric energy internal distribution, some current transducers and current and temperature transducers (9.1, 9.2), respectively, elements (7) for electric switch and elements (8) of power control which feed various types of electrical loads (10.1-n, 11.1-n, 12.1-n).
Patent RO-131464-A0 (RO)
Title: Integrated system for simultaneously measuring propagation rates of the front of the flame and pressure wave in case of explosions
Inventor: GHICIOI EMILIAN
IPC: G01N31/12
Filed: 2015-10-19
Abstract: The invention relates to an integrated system for simultaneously measuring the propagation rates of the front of the flame and the pressure wave, in case of explosions of inflammable air-gas mixtures, meant to be used for studying the behaviour thereof depending on the concentration value, on the type of initiation source and on the propagation distance, and for determining the character of explosions. According to the invention, the system consists of an assembly comprising optical transducers (L, L, L, L), which may comprise the NIR spectrum and pressure transducers (P, P, P, P), placed on a cylindrical shock tube (TSC), at certain distances (d, d, d, d) as related to a firing source (SA) supplied from a dedicated supply source (SSA) which initiates the inflammable gas-air explosion, case in which the sensors supplied from some dedicated sources (SP, SL) provide useful signals for simultaneously recording the pressure wave and the flame front, by means of a digital multi-channel memory oscilloscope (ODMM), having at least four channels (CL, CL, CL, CL) for the optical sensors, and other four channels (CP, CP, CP, CP) for the pressure sensors, the trigger (T) of which is controlled by the explosion initiation from the firing source (SSA), making possible the setting of protective systems location so that the pressure wave precedes the flame front, thereby limiting the effects of an incipient explosion.
Patent RO-133679-A0 (RO)
Title: Light sensor based on laminated structure of thin layers
Inventor: LORINCZI ADAM
IPC: G01J1/42
Filed: 2018-11-29
Abstract: The invention relates to a light sensor based on a laminated structure and to a process for manufacturing the structure. According to the invention, the laminated structure consists of three thin layers deposited on a glass support in the following order: Cu, AsS, Cu, the thickness of the Cu layers ranging between 15...90 nm, and the thickness of the AsSlayer ranging between 250...800 nm. The claimed process for manufacturing the laminated structure consists of layer deposition in vacuum, by the pulsed laser deposition (PLD) method, dedicated masks, specially made by 3D printing technique, being used for controlling the deposition.
Patent AU-2002951170-A0 (AU)
Title: Improved security strap system
IPC: B60R22/10
Filed: 2002-09-03
Abstract: A connecting system for a child car seat (31) of a type which can either be rearward or forward facing. Separate strap paths (33, 34) are associated with the seat for each of the rearward and facing positions of the child car seat. The connecting system has a connecting strap (36) with latches (37) at either end adapted to engage with latching bars on the vehicle. The connecting strap (36) is fixed into a strap path (30) and long enough to permit each end to be passed through the front path (33) from opposite sides to cross and to extend out the opposite side of the front path when the child car seat is in the rearward facing position or be passed through the rear path (7) from opposite sides to cross and to extend out the opposite side of the rear path when the child car seat is in the forward facing position. <IMAGE>
Patent MA-26980-A1 (MA)
Title: Antagonistes des recepteurs d'histamine.
Inventor: JENKINSON STEPHEN
IPC: A61K45/00
Filed: 2003-07-11
Abstract: Antagonistes des récepteurs d'histamine La présente invention propose une association (a) d'un antagoniste des récepteurs d'histamine H1 et (b) d'un antagoniste qui est au moins 10 fois plus sélectif pour le récepteur d'histamine H4 que pour le récepteur d'histamine H3, des compositions la contenant ainsi que leurs utilisations.
Patent MA-27649-A1 (MA)
Inventor: DEFOSSA ELISABETH
IPC: C07D213/82
Filed: 2005-07-22
Abstract: The invention relates to compounds of formula (I) wherein the radicals have the cited meaning, in addition to the physiologically compatible salts thereof. The compounds, for example, can be used as medicaments for preventing and treating type 2 diabetes.
Patent MA-27963-A1 (MA)
Title: Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
Inventor: DESOS PATRICE
IPC: C07D/
Filed: 2005-11-22
Abstract: NOUVEAUX DERIVES DE BENZOTHIAZINE ET BENZOTHIADIAZINE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT Composés de formule (I) : dans laquelle : R1 représente hydrogène, alkyle ou cycloalkyle, R2 représente hydrogène, halogène ou hydroxy, A représente CR3R4 ou NR3, où R3 et R4 sont tels que définis dans la description, Y représente une chaîne alkylène telle que décrite dans la description, X représente NR5R6, S(O)nR7, OR8, C(O)R9, amidino ou hétérocycle, leurs isomères ainsi que leurs sels d'addition. Médicaments.