baber/WOPTO huggingface dataset:
Patent NZ-554433-A (NZ)
Title: Strontium salts of sulphonic acids suitable for the treatment of osteoarthritis and osteoporosis
Inventor: LEFOULON FRANCOIS
Filed: 2007-04-11
Abstract: Disclosed is a sulphonic acid of formula (I): A-B-SO3H wherein: A represents a group selected from OH, NH2, SO3H and CO2H; B represents an arylene group or a linear or branched C1-C12alkylene chain optionally substituted by one or more groups selected from hydroxy, oxo, amino, SO3H and CO2H and in which one or more carbon atoms is optionally replaced by an oxygen atom, by a nitrogen atom or by an SO2 group, with the exclusion of strontium bis(aminomethanesulphonate), strontium methane disulphonate, strontium 1,3-benzenedisulphonate, strontium 6-suiphonatohexanoate, strontium 1,5-naphthalenedisulphonate, strontium 1,6-naphthalenedisulphonate, strontium bis(6-hydroxy-2-naphthalenesulphonate), strontium 2-oxo-1,3-propane- disulphonate, strontium hydroxymethanesulphonate, strontium bis(4-aminobenzene-sulphonate), strontium bis(2- aminobenzene-sulphonate), strontium bis(3-aminobenzene-sulphonate), strontium 1,2-ethanedisulphonate and strontium 3-amino-3-carboxy-1-propanesulphonate chloride, and wherein: arylene being understood to be phenylene, biphenylylene or naphthylene, each of those groups being optionally substituted by one or more identical or different groups selected from linear or branched C1-C12alkylene, OH, NH2, SO3H and CO2H. Also disclosed is a process for the preparation of a strontium salt by reaction of a sulphonic acid of formula (I) with strontium hydroxide, followed by isolation of the strontium salt so obtained; and alternatively by reaction of the sodium or potassium salt of a sulphonic acid of formula (I): with strontium chloride, followed by isolation of the strontium salt so obtained. These strontium salts are suitable in the manufacture of medicaments for use in the prevention or treatment of osteoarthritis and osteoporosis.
Patent NZ-566763-A (NZ)
Title: Exendin-4 for treating diabetes, obesity and reducing body weight
Inventor: FINEMAN MARK
IPC: A61K9/00
Filed: 2006-08-18
Abstract: The use of exendin-4 for treating diabetes and overweight patients and obesity in humans by a once weekly administration to achieve a mean steady state plasma concentration of exendin-4 at 170 pg/ml to 290 pg/ml for at least a month. The exendin-4 can be formulated in a medicament comprising 5% (w/w) exendin-4, 2% (w/w) sucrose and 93% (w/w) poly(lactide-co-glycolide) copolymer. The diabetes can be Type 1 diabetes or Type 2 diabetes.
Patent NZ-569768-A (NZ)
Title: Boat trailer rollers
Inventor: BULL ROYSTON DOUGLAS
Filed: 2008-07-10
Abstract: A non-pneumatic load supporting roller (10) having a bearing (12) for rotationally supporting the roller. The roller has an outer peripheral tread (16) disposed about the bearing, the tread defining a rolling surface contact region located in a rotational plane that is cylindrical, frusto-conical or both cylindrical and frusto-conical. The rolling surface region is formed by outwardly facing end zone regions (25) of a plurality of radially extending projections (17) spaced from one another both in an axial direction of the rotational plane and in a circumferential direction, the radial projections being arranged in lines (24, 26) that are parallel to the axis of rotation (23) of the roller or are curved relative to a line parallel to the axis of rotation of the roller.
Patent NZ-573325-A (NZ)
Title: Pyrazolealkanamide substituted thiophenes as ampa potentiators
Inventor: MACLEAN JOHN KINNAIRD FERGUSON
IPC: A61K31/497
Filed: 2007-07-02
Abstract: Disclosed are pyrazolealkanamide substituted thiophenes represented by general formula (I), or pharmaceutically acceptable salts thereof, wherein the other substituents are disclosed within the specification. Also disclose is the use of the above mentioned compounds for the manufacture of a medicament for the treatment or prevention of neurodegenerative disorders, cognitive or memory dysfunction, memory and learning disorders, attention disorder, trauma, stroke, epilepsy, Alzheimer's disease, depression, schizophrenia, psychotic disorders, anxiety, autism, a disorder or disease resulting from neurotic agents, substance abuse, alcohol psychiatric disorders, Parkinson's Disease, sleep disorders or narcolepsy or other conditions resulting from sleep deprivation.
Patent NZ-574548-A (NZ)
Title: Hair styling agents giving a high degere of hold
Inventor: KNAPPE THORSTEN
IPC: A61Q5/06
Filed: 2007-08-16
Abstract: An agent that can temporarily shape keratin fibres or hair. The agent comprises: a) A copolymer made up from - A monomer A1 selected from acrylic acid, methacrylic acid, acrylic acid alkyl esters and methacrylic acid alkyl esters; - A monomer A2 selected from acrylic acid hydroxyalkyl esters and methacrylic acid hydroxyalkyl esters; and - A monomer A3 selected from succinic acid monoalkyl esters and succinic acid dialkyl; and b) A film-forming agent and/or setting amphoteric polymer selected from the group of (i) methacryloylbetaine/alkyl methacrylate copolymers, (ii) copolymers of monomers having carboxy and/or sulfone groups and monomers having amino groups, and (iii) copolymers of N-octyl acrylamide, metyl methacrylate, hydroxypropyl methacrylate, N-tert-butylaminoethyl methacrylate and acrylic acid.
Patent NZ-574932-A (NZ)
Title: Implement for automatically milking a diary animal comprising a milking parlour, a sensor and a milking robot
Inventor: VAN DEN BERG KAREL
IPC: A01J5/017
Filed: 2007-08-28
Abstract: Disclosed is an implement for automatically milking a diary animal. The implement comprises a milking parlour (1), a sensor (100) for observing at least a part of the diary animal and a milking robot (3) for automatically attaching a teat cup (28) to a teat (46). The robot (3) comprises a robot control that is operatively connected to the sensor (100). The sensor (100) comprises a radiation source (108) for emitting electromagnetic radiation and a matrix with a plurality of rows and columns of receivers for receiving electromagnetic radiation from the diary animal. The sensor (100) further comprises a lens (106) and a sensor control means. The lens (106) is used for imaging the reflected electromagnetic radiation onto the receivers. The sensor control means are operatively connected to the radiation source (108) in order to modulate the electromagnetic radiation. The sensor control means are designed to determine a phase difference between the emitted and the reflected electromagnetic radiation in order to calculate distances from the sensor (100) to a plurality of points on the dairy animal.
Patent NZ-575425-A (NZ)
Title: Aerosol formulation for the inhalation of beta agonists
Inventor: RADAU KIRSTEN
IPC: A61K47/10
Filed: 2007-08-16
Abstract: Disclosed is a medicament formulation, including as active substance one or more compounds of general formula 1 e.g. 6-hydroxy-B-{ 1-hydroxy-2-[2-(4-methoxy-phenyl)-1 , 1-dimethyl-ethylamino]ethyl} -4H-benzo[1,4]oxazin-3-one wherein R1 denotes hydrogen; R2 denotes hydrogen; R3 denotes OH, fluorine, chlorine, methoxy, ethoxy, or -O-CH2-COOH and X- denotes a mono- or polysubstituted negatively charged anion; an active substance 2 selected from among budesonide, ciclesonide, a tiotropium salt, an antioxidant in the form of butylhydroxytoluene, as well as ethanol or a mixture of water and ethanol as the solvent for the treatment of a respiratory condition.
Patent NZ-575883-A (NZ)
Title: Scaffolding structure with a walking platform moveable along the frame
Inventor: SENIOR BRUCE JOSEPH
IPC: E04G7/00
Filed: 2009-03-30
Abstract: A scaffold bridge comprising a support frame, a walking platform 6 to be supported by the frame, and a runner assembly 13. The runner assembly 13 is adapted so it moves longitudinally along the frame to carry the platform 6 from an end part of the frame to an opposite end part of the frame so the platform 6 is substantially in its normal assembled disposition with respect to the frame.
Patent NZ-575990-A (NZ)
Title: Device for sampling biological tissue for the identification of animals
Inventor: HILPERT JEAN-JACQUES
IPC: A01K11/00
Filed: 2007-10-01
Abstract: Device 1 for sampling biological tissue, comprises a chamber 4 that can contain a chemical product for treating a sample of biological tissue, a hollow needle 3 that has a cavity that ends in a first opening 34 at a first tip 31 and in a second opening 35 at a second tip 32, and an attachment part 22 of the hollow needle 3, formed integral with the chamber 4. The hollow needle 3 has a cutting edge 36 at the second tip 32 that is able to cut out the biological tissue for the purpose of creating a sample that is received in the cavity when the sampling device 1 is pushed into the biological tissue. The attachment part 22 has a channel that emerges from the base of the chamber and ends in an orifice. The channel has dimensions that can hold the proximal part of the hollow needle 3 that carries the first tip 31. The base of the chamber 4 comprises a partition 211 that can be pierced by the first tip 31 of the hollow needle 3 when the sampling device 1 is pushed into the biological tissue.
Patent NZ-578932-A (NZ)
Title: Surface-treated calcium carbonate and its use in purifying water
Inventor: GERARD DANIEL E
IPC: C02F103/32
Filed: 2008-03-19
Abstract: A process for the purification of water is disclosed, wherein a surface-reacted natural calcium carbonate is brought into contact with the water to be purified, the surface reacted natural calcium carbonate being the reaction product of a natural calcium carbonate with an acid and carbon dioxide, which is formed in situ by the acid treatment and/or supplied externally, and the surface-reacted natural calcium carbonate being prepared as an aqueous suspension having a pH of greater than 6.0, measured at 20 Deg. C, and a polymeric flocculent such as polyacrylamide is added to the water to be purified subsequent to the addition of the surface-reacted natural calcium carbonate.
Patent NZ-585465-A (NZ)
Title: Monoclonal antibodies which bind to the extracellular domain of the axl receptor tyrosine kinase
Inventor: HETTMANN THORE
IPC: C07K16/28
Filed: 2008-11-12
Abstract: Disclosed is a monoclonal antibody, as defined in the complete specification, which binds to the extracellular domain of AXL and at least partially inhibits AXL activity. Also disclosed is the use of said monoclonal antibody for the manufacture of a pharmaceutical composition for the diagnosis, prevention or treatment of a hyperproliferative disease.
Patent NZ-585513-A (NZ)
Title: Triazolo[4,5-d]pyrimidine compounds for treatment of abdominal aortic aneurysms
Inventor: MICHEL JEAN-BAPTISTE
IPC: A61P9/10
Filed: 2008-12-02
Abstract: Disclosed herein is the use of the compound { 1S-[1á,2á,3â 1S*,2R*)5â]} -3-(7-{ [2-(3,4-difluorophenyl)cyclopropyl]amino} -5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (compound of formula (A))for the manufacture of a medicament for the treatment or prevention of abdominal aortic aneurysms.
Patent NZ-585559-A (NZ)
Title: Humanized antibodies against tl1a
Inventor: SMITH RODGER
IPC: A61K39/395
Filed: 2008-11-13
Abstract: Disclosed is an isolated antigen-binding polypeptide that binds specifically to TL1A, comprising: (a) a humanized antibody heavy chain variable region comprising: (1) a CDR-H1 comprising an amino acid sequence of TSNMGVV as shown in SEQ ID NO:7; (2) a CDR-H2 comprising an amino acid sequence of HILWDDREYSNPALKS as shown in SEQ ID NO:8 and; (3) a CDR-H3 comprising an amino acid sequence of MSRNYYGSSYVMDY as shown in SEQ ID NO:9; and (b) a humanized antibody light chain variable region comprising: (1) a CDR-L1 comprising an amino acid sequence of SASSSVNYMH as shown in SEQ ID NO:35; (2) a CDR-L2 comprising an amino acid sequence of STSNLAS as shown in SEQ ID NO:36 and; (3) a CDR-L3 comprising an amino acid sequence of HQWNNYGT as shown in SEQ ID NO:37. Also disclosed is the use of the polypeptide in the manufacture of a medicament used for treating or diagnosing an inflammatory disease or condition in a patient in need thereof.
Patent NZ-588353-A (NZ)
Title: Limk2 inhibitors, compositions comprising them, and methods of their use
Inventor: BURGOON HUGH ALFRED
IPC: A61P25/28
Filed: 2009-04-20
Abstract: Disclosed are pyrrolo-pyrimidine based compounds represented by general formula (I), or pharmaceutically acceptable salts thereof. Also disclosed is the use of the compounds for treating, managing or preventing a disease or disorder affecting vision in a patient, such as lowering intraocular pressure in a patient.
Patent NZ-588849-A (NZ)
Title: Pharmaceutical composition comprising 6-(4-bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3h-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide
Inventor: BATEMAN NICOLA FRANCES
IPC: A61K9/14
Filed: 2009-03-26
Abstract: Disclosed is a pharmaceutical composition comprising a hydrogen sulphate salt of 6-( 4-bromo-2-chloro-phenylamino )-7 -fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide, and a carrier matrix comprising one or more pharmaceutically acceptable carriers selected from the following groups: (a) d-alpha-tocopheryl polyethylene glycol 1000 succinate; (b) polyglycolised glycerides; (c) polyethylene glycols (PEGs); and (d) hard fats; and wherein the hydrogen sulphate salt of 6-( 4-bromo-2-chloro-phenylamino )-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide is dispersed within the carrier matrix. The pharmaceutical composition is used to treat cancer.
Patent NZ-592552-A (NZ)
Title: Methods and compositions for diagnosis and prognosis of renal injury and renal failure
Inventor: ANDERBERG JOSEPH
IPC: C12Q1/68
Filed: 2009-11-21
Abstract: NZ 592552 Disclosed is a method for determining a likelihood of a future acute change in renal function in a subject, said method comprising: performing one or more assays configured to detect a growth-regulated alpha protein, each assay comprising contacting ex vivo a body fluid sample comprising urine or plasma obtained previously from a subject with an antibody or fragment thereof capable of binding to growth-regulated alpha protein under conditions sufficient for the antibody or fragment thereof to bind selectively to the kidney injury marker; determining results of the one or more assays, each assay result comprising a measured amount of the antibody or fragment thereof bound to a growth-regulated alpha protein; correlating the assay results to a measured concentration of a growth-regulated alpha protein in the body fluid sample; and assigning an increased likelihood of a future acute change in renal function in the subject when the measured concentration in the sample is above the threshold relative to a likelihood thereof when the measured concentration is below the threshold; or assigning a decreased likelihood of a future acute change in renal function in the subject when the measured concentration in the sample is below the threshold, relative to a likelihood thereof when the measured concentration is above the threshold. The disclosed method is subject to the proviso that the subject is not a renal transplant recipient and subject to the proviso that the subject does not have a pre-diagnosed acute kidney injury (AKI) or pre-diagnosed acute renal failure (ARF) when the body fluid sample is taken.
Patent NZ-593023-A (NZ)
Title: A positioning system and method
Inventor: KELLAR WILLIAM JAMES
IPC: G01S5/14
Filed: 2009-12-02
Abstract: 593023 A positioning method includes calculating a lower accuracy positioning solution. An offset to the lower accuracy positioning solution is applied to form a final positioning solution if a higher accuracy positioning solution is unavailable. The offset is representative of a difference between the lower accuracy positioning solution and the higher accuracy positioning solution at a point in time when the higher accuracy positioning solution was last available. A positioning method includes continuously determining whether the higher accuracy positioning solution has again become available; and in the event that the higher accuracy positioning solution has become available; calculating the higher accuracy positioning solution; applying a reacquisition offset to the higher accuracy positioning solution to form an adjusted higher accuracy positioning solution; and setting the adjusted higher accuracy position solution as a new final positioning solution. A positioning system and method for a vehicle are disclosed. The positioning system comprises a higher accuracy positioning module (1331) configured to calculate a higher accuracy positioning solution (line 4000) for the vehicle; a lower accuracy positioning module (1332) configured to calculate a lower accuracy positioning solution (line 5000) for the vehicle; and a correction module (1333) in communication with the higher accuracy positioning module and the lower accuracy positioning module. The correction module is configured to provide a final positioning solution (13334) to guide the vehicle along a predetermined path. The correction module is further configured to maintain an offset representative (L) of the difference between the higher accuracy positioning solution and the lower accuracy positioning solution whilst the higher accuracy positioning solution is reliable; apply the offset to the lower accuracy positioning solution to form the final positioning solution in the event that that higher accuracy positioning solution becomes unreliable; and applying a reacquisition offset to the higher accuracy positioning solution to form an adjusted higher accuracy positioning solution if the higher accuracy positioning solution was determined to be unreliable but has again been determined to be reliable.
Patent NZ-593497-A (NZ)
Title: Animal digestion monitoring system with bolus having a transmitter and designed to be retained in the dorsal sac of the rumen
Inventor: LAPORTE-URIBE JOSE ALBERTO
IPC: A61B5/00
Filed: 2011-06-16
Abstract: Disclosed is a system (10) for monitoring digestive efficiency within the rumen of one or more ruminant animals (1). The system (10) includes one or more rumen boluses (150) each shaped and sized to be retained within, or residing within, the dorsal sac of the rumen of the associated animal (1). Each bolus (150) is comprised of a temperature sensor to provide data indicative of temperature within the rumen, a pH sensor to provide data indicative of pH within the rumen, a redox sensor to provide data indicative of the oxidation-reduction potential within the rumen. Each bolus (150) also includes a wireless transmitter for transmitting data or derived parameters to a remote station (14). In each bolus (150) or at a remote station (14) is a processor arranged to derive from the sensor data one or more parameters indicative of animal digestive efficiency.
Patent NZ-594331-A (NZ)
Title: Improvements in window hardware
Inventor: WAITAI RANA
IPC: E05C17/00
Filed: 2011-07-29
Abstract: 594331 A window sash configured to be moveably mounted to a window frame, the window frame having an exterior side and an interior side, and where the window frame includes a track, and the sash includes a guide. The guide is configured to engage with the track, and the interaction of the guide and track defines a range of motion for the sash with respect to the window frame. The guide has an upper side and a lower side. The upper side of the track is configured with a first catchment portion for the upper side of the guide, and the lower side of the track is configured with a second catchment portion for the lower side of the guide. The second catchment portion is positioned closer to the exterior side of the frame relative to the first catchment portion. The vertical distance between the upper and lower sides of the track is wider at the exterior of the frame than between the first and second catchment portions.
Patent NZ-596186-A (NZ)
Title: Lipid compositions
Inventor: BUTLER DAVID
IPC: A61K9/127
Filed: 2010-05-05
Abstract: NZ 596186 The disclosure relates to a composition comprising: a sterol, a neutral lipid, a PEG or PEG-modified lipid, and a lipid of formula (V) which contains a piperazine moietie, and optionally a targeting lipid comprising N-acetyl galactosamine as a targeting moiety. Also disclosed are methods of making compounds of formula (V). These lipid compositions are useful for therapeutic agent delivery of nucleic acids as well as nucleic acid-lipid particle compositions.
Patent NZ-597277-A (NZ)
Title: A method and an apparatus for continuously sterilizing water for spraying the pistons in a piston pump or a homogenizer
Inventor: JOHANSSON FREDRIK
IPC: C02F9/00
Filed: 2010-06-23
Abstract: Disclosed is a method and an apparatus for continuously sterilizing water for spraying the pistons in a piston pump or a homogenizer. The heating takes place in a first stage in a first heat exchanger (3) and in a second stage in a second heat exchanger (5). The first heat exchanger (3) operates regeneratively so that incoming cold water is heated in the first heat exchanger (3) by water which has been heated by steam in the second heat exchanger. After the second heat exchanger (5) the water is at a temperature of at least 1210°C and is to stay at this temperature in a holding cell (8) during a predetermined period of time. After the water has been cooled regeneratively in the first heat exchanger (3) it is to be at a temperature which exceeds 75°C.
Patent NZ-597470-A (NZ)
Title: Therapeutic peptides, polypeptides ans nucleic acid sequences
Inventor: MORGAN RICHARD
IPC: C07K14/82
Filed: 2010-07-13
Abstract: NZ 597470 Disclosed is a peptide fragment or a polypeptide fragment derived from the Engrailed-2 (EN2) protein. The disclosed EN2 fragment is as defined in the specification, is less than 40 amino acids in length and is used in the treatment of cancer.
Patent NZ-599870-A (NZ)
Title: Methods of inhibiting ethylene responses in plants using dicyclopropene compounds
Inventor: SISLER EDWARD C
IPC: A01G7/06
Filed: 2008-06-13
Abstract: ABSTRACT - 599870 The disclosure relates to dicyclopropene compounds represented by structural formula (I), or an enantiomer, stereoisomer or a salt thereof, wherein the variables are as defined in the specification. These dicyclopropene compounds are used for inhibiting an ethylene response in a plant, wherein said plant may be a whole plant or any portions thereof, a field crop, landscape plant, potted plant, cut flower or harvested fruit or vegetable. The disclosure also relates to a method of inhibiting an ethylene response in a plant, comprising applying to the plant an effective ethylene response-inhibiting amount said compound by contacting said plant to a gas, liquid, solid, salt or mixture thereof of said compound, wherein application is preferably carried out by spraying said plant with a solution comprising said compound or contacting said plant to a solid comprising said compound.
Patent NZ-600191-A (NZ)
Title: Method for reducing temperature stress of plants
Inventor: NAGASAWA ASAKO
IPC: A01N37/30
Filed: 2010-12-09
Abstract: 600191 Disclosed is a method for reducing temperature stress of plants which comprises applying an effective amount of one or more compounds selected from the group consisting of a compound represented by the formula (I) and an agriculturally acceptable salt thereof to a plant that has been exposed to or to be exposed to a temperature stress factor. Examples of compounds of formula (I) are: 4-oxo-4-(2-phenylethyl)aminobutyric acid, methyl 4-oxo-4-(4-phenylbutyl)aminobutyrate, methyl 4-oxo-4-(2-phenylethyl)aminobutyrate, 4-oxo-4-(4-phenylbutyl)aminobutyric acid, 5-oxo-5-[2-(3-indolyl)ethyl]aminovaleric acid, 5-oxo-5-[(1-naphthyl)methyl]aminovaleric acid, and methyl 4-oxo-4-[2-(4-iodophenyl)ethyl]aminobutyrate.