baber/WOPTO huggingface dataset:
Patent EP-1549670-B1 (EP)
Inventor: VRIJBLOED JAN WIM
IPC: A61K38/00
Filed: 2002-10-02
Granted: 2008-04-30
Abstract: Template-fixed beta-hairpin peptidomimetics of the general formula (I), wherein Z is a template-fixed chain of 12 alpha-amino acid residues which, depending on their positions in the chain (counted starting from the N-terminal amino acid) are Gly or Pro, or of certain types, at least one of these residues being of the type of N-substituted glycines, which types, as the remaining symbols in the above formula, are defined in the description and the claims, and salts thereof, have the property to inhibit the growth of or to kill microorganisms. They can be used as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials or as medicaments to treat or prevent infections. These beta-hairpin peptidomimetics can be manufactured by processes which are based on a mixed solid- and solution phase synthetic strategy.
Patent EP-1508338-B1 (EP)
Inventor: SINGH MAHAVIR PROF DR
IPC: A61K39/00
Filed: 2003-08-22
Granted: 2008-12-31
Abstract: The present invention relates to the use of highly immunogenic protein antigens for vaccination and immunotherapy of cancer in humans and animals. In particular, the present invention relates to the use of a wild-type or a recombinant mycobacterial PstS1 protein or wild-type or recombinant Hsp16 protein for the preparation of a vaccine or therapeutical composition for the treatment of cancer, in particular for the treatment of urothelial carcinoma of the bladder or mama carcinoma.
Patent EP-1408034-B1 (EP)
Inventor: SCHULZ HANS-HERRMANN
IPC: A61K31/4709
Filed: 2000-12-22
Granted: 2007-08-08
Abstract: The use of active agent(s) (A) selected from 4-oxo-quinoline-3-carboxylic acid derivatives (including naphthyridine or quinolizine analogs) (I) or (II) for topical and/or local treatment or prophylaxis of bacterial diseases in humans or animals is new.  The use of one or more active agent(s) (A) selected from 4-oxo-quinoline-3-carboxylic acid derivatives (including naphthyridine or quinolizine analogs) of formula (I) or (II) and their hydrates, acid addition salts, carboxylate salts, enantiomers, diastereomers, racemates or mixtures, optionally together with auxiliaries, is claimed for the preparation of medicaments for topical and/or local treatment or prophylaxis of bacterial diseases in humans or animals. The use of ciprofloxacin for the treatment of eye or ear diseases is excluded.  A  =  CH, C(halogen), C(Me), C(CN), C(OMe), C(OCHF2) or N;  R1  =  1-5C alkyl, 2-5C alkenyl, 2-fluoroethyl, cycloalkyl, bicycloalkyl, 2-fluorocyclopropyl, 1-oxetan-3-yl, NHMe, optionally substituted phenyl or pyridyl;  or A + R1  =  C-O-CH2-CH(Me)-;  R2  =  H or 1-3C alkyl (optionally substituted by OH, halo or NH2);  R3  =  H, halo, Me, NH2 or NHNH2;  R4  =  H, halo or NH2;  R5, R'2  =  optionally substituted mono-, bi- or tricyclic alicyclic system (optionally containing double bond(s)) or mono-, bi- or tricyclic aromatic system (both optionally containing heteroatom(s));  R'1  =  H or 1-3C alkyl. An Independent claim is included for gel formulations containing one or more (A).
Patent EP-1344964-B1 (EP)
Inventor: POISSON CARINE
IPC: F16H59/44
Filed: 2003-03-14
Granted: 2011-05-04
Abstract: The method of gear change control for a motor vehicle automatic transmission uses the vehicle speed and engine output to determine the required transmission gear ratio. The higher gears are released when the engine regime (Nmot) attains a value (Nmax) determined from the gear change commands and variation in the regime during declutching of the transmission. The regime variation is a function of the gear range and the engine speed.
Patent EP-1465557-B1 (EP)
Inventor: FARRAR RICHARD
IPC: A61F2/40
Filed: 2003-01-16
Granted: 2006-10-11
Abstract: A method of making a component (2) of an orthopaedic joint prosthesis, which has a bearing surface whose shape corresponds approximately to a part of a sphere and is symmetrical about its polar axis, involves use of a cutting tool (6) which has a circular cutting edge (12) and which can be rotated about an axis (8) which is perpendicular to the plane containing the said cutting edge (12). The method involves (a) rotating the component about its polar axis (4) and rotating the cutting tool (6) about its axis (8), with the cutting edge (12) of the cutting tool (6) in contact with the surface of the component (2); (b) moving the cutting tool (i) in a direction parallel to the polar axis (4) of the component (2) while leaving the angle between the axis of the cutting tool (6) and the polar axis of the component (2) unchanged, and (ii) along its axis (8); and (c) repeating step (a). The movements (i) and (ii) of the cutting tool (6) cause the radius of curvature of the bearing surface to change continuously and monotonically as the angle between the radius and the polar axis of the component changes, so that the shape of the bearing surface deviates from that of a true sphere in such a way that discontinuities in the shape of the bearing surface as a result of individual movements are minimised.
Patent EP-1495137-B1 (EP)
Inventor: OLSSON CHARLOTTA
IPC: C12Q1/68
Filed: 2003-04-04
Granted: 2005-09-14
Abstract: A method for determining the sequence of a nucleic acid molecule includes the steps of: a) providing a single-stranded form of the nucleic acid molecule; b) hybridizing a primer to the single stranded form of the nucleic acid molecule to form a template/primer complex; c) enzymatically extending the primer by the addition of a polymerase and a mixture of at least one nucleotide and at least one labeled derivative of the at least one nucleotide, wherein the at least one labeled derivative of the at least one nucleotide includes a label linked to the nucleotide via a cleavable link and wherein the amount of labeled derivative of the at least one nucleotide in the mixture of the at least one nucleotide and the labeled derivative of the at least one nucleotide is within the range of 1-50 mole-%, 1-40 mole-%, 1-30 mole-%, or 1-20 mole-%. d) determining the type of nucleotide added to the primer; and e) repeating steps c) to d) at least once.
Patent EP-1489902-B1 (EP)
Inventor: CARLEY JOSEPH CHRISTOPHER
IPC: A01K63/04
Filed: 2003-03-26
Granted: 2008-12-10
Abstract: The present invention relates to filter devices and methods of using such devices for mechanical, chemical and biological filtration pond and/or aquarium water.
Patent EP-1472459-B1 (EP)
Inventor: PECORARI GABRIELE
IPC: F04B1/107
Filed: 2003-01-13
Granted: 2006-12-13
Abstract: A rotary displacement machine with radial pistons, comprising a supporting structure, with a main body and a cover, a centrally mounted distributor, a rotating unit consisting of a rotor provided with a number of radially extending cylindrical chambers, each chamber containing a respective piston mounted for sliding movement in a first direction along a first axis coaxial with the longitudinal centerline of the respective cylindrical chamber; wherein the rotor is mounted by support bearings means in the main body and cover and the distributor is mounted to float within a space defined by the cover and with coaxial relationship in the rotor by bearing means.
Patent EP-1516105-B1 (EP)
Inventor: CADEDDU LEONARDO
IPC: F01C20/18
Filed: 2003-06-17
Granted: 2012-02-22
Abstract: A fluidic machine has a fixed body, an external orbital member rotatable around a first rotational axis and internal gear teeth including a first teeth number, a transmission member rotatable around a second rotational axis, an internal orbital member supported by the transmission member, having external gear teeth including a second teeth number different from the first teeth number and meshing with the internal gear teeth of the external orbital member, thus determining among the gear teeth of the two orbital members spaces whose volume is variable during rotation. One of the orbital members is mounted axially displaceable and is pushed by an elastic push member in the direction producing a more extended engagement with the other orbital member, and a piston, mounted displaceable within the non-axially displaceable orbital member and resting against the axially displaceable orbital member, is subjected, to the pressure of the high pressure connection.
Patent EP-1525066-B1 (EP)
Inventor: KRUSZYNSKI JACEK
IPC: B23B27/16
Filed: 2003-07-26
Granted: 2006-09-13
Abstract: The full borer has the main cutter (34) of the outer cutting plate (22) divided into a radially inner working part (50) followed on the outside by a shelling part (52) extending to the outer plate corner (36). The two parts enclose an angle of 95-120degrees with the shelling part ending at 72-87degrees to the outer plate corner.
Patent EP-1490672-B1 (EP)
Inventor: WATKINS KENNETH S
IPC: G01N17/00
Filed: 2003-03-05
Granted: 2011-12-21
Abstract: An electrical condition monitoring method utilizes measurement of electrical resistivity of a conductive composite degradation sensor to monitor environmentally induced degradation of a polymeric product such as insulated wire and cable. The degradation sensor comprises a polymeric matrix and conductive filler. The polymeric matrix may be a polymer used in the product, or it may be a polymer with degradation properties similar to that of a polymer used in the product. The method comprises a means for communicating the resistivity to a measuring instrument and a means to correlate resistivity of the degradation sensor with environmentally induced degradation of the product.
Patent EP-1487963-B1 (EP)
Inventor: KLAPPROTH HOLGER
IPC: G01N33/543
Filed: 2003-03-05
Granted: 2012-01-04
Abstract: Die vorliegende Erfindung betrifft eine Vorrichtung zur Detektion eines Lumineszenzereignisses in, an oder in der unmittelbaren Umgebung einer Zelle, eines Zellverbandes oder eines Gewebes, die folgende Merkmale aufweist: (a) ein Trägerelement (1) mit einer für das direkte oder indirekte Ankoppeln von Zellen präparierten Oberfläche (100), (b) wenigstens einen optischen Detektor (2) zum Empfangen eines Lumineszenzsignals, der in dem Trägerelement (1) unterhalb der Oberfläche (100) integriert ist, gekennzeichnet durch folgende weitere Merkmale: (c) eine die Oberfläche (100) unter Bildung eines Hohlraumes (70) überdeckende Abdeckung (7), die eine Zuflussöffnung (8) und eine Abflussöffnung (9) aufweist, (d) eine an die Zuflussöffnung (8) angeschlossene Anregungsquelle (21).
Patent EP-1546162-B1 (EP)
Inventor: CALI JAMES J
IPC: G01N33/53
Filed: 2003-09-16
Granted: 2011-06-22
Abstract: The invention provides compounds, compositions, methods, substrates, and kits useful for analyzing the metabolic activity in cells, tissue, and animals and for screening test compounds for their effect on cytochrome P450 activity. In particular, a one-step and two-step methods using luminogenic molecules, e.g. luciferins or coelenterazines, that are cytochrome P450 substrates and that are also bioluminescent enzyme, e.g., luciferase, pro-substrates are provided. The present method further provides a method for stabilizing and prolonging the luminescent signal in a luciferase-based assay using luciferase stabilizing agents such as reversible lucifetrase inhibitors.
Patent EP-1554067-B1 (EP)
Inventor: BOLT PIETER JAN
IPC: B21D22/21
Filed: 2003-10-23
Granted: 2008-09-17
Abstract: A method and apparatus for deep drawing a product from a blank ( 5 ), in which, during deep drawing, the blank ( 5 ) is held near its edge by a downholder ( 8 ) against a die ring cooperating with the downholder ( 8 ), thereby preventing, at least reducing wrinkle formation in the blank, by adjusting, at the beginning of deep drawing, the downholder ( 8 ) such that a downholder ( 8 ) force exerted by the downholder ( 8 ) on the edge of the blank is relatively small, and by controlling, during the further course of the process, the downholder ( 8 ) on the basis of a predetermined thickness trend of the mentioned edge during deep drawing and/or a trend or critical value derived from this thickness trend.
Patent EP-1516113-B1 (EP)
Inventor: HAUBNER FRANK
IPC: F02F1/42
Filed: 2003-06-18
Granted: 2007-11-07
Abstract: The invention relates to a cylinder head comprising a water jacket that is delimited by a flame deck and an oil deck in a water-cooled reciprocating engine with cylinders that are arranged in series, each of said cylinders having at least one intake valve comprising intake ducts and two exhaust valves, whose exhausts open into exhaust ducts, in addition to a receptacle for a fuel injector or a spark plug that is located between the intake valve and the exhaust valves. The cylinder head is characterised in that a system of channels is provided at least in the vicinity of the exhaust side of each cylinder in order to conduct the coolant in the water jacket, whereby the coolant supply is conducted through said system from the exterior on one side of the exhaust duct towards the receptacle and is returned from the interior to the exterior on the other side of the exhaust duct and in that an overflow channel is provided.
Patent EP-1524925-B1 (EP)
Inventor: MANGOLD RAINER
IPC: A43B17/00
Filed: 2003-07-25
Granted: 2008-08-20
Abstract: An insole (for shoes) is in the form of a disposable product having a maximum thickness of 3 mm and consisting essentially of a liquid-absorbing fiber fleece material made of or based on cellulose fiber. The insole is formed by a single wadding fleece layer ( 4 ) made of cellulose fiber material having 25% by weight of heat meltable binding fibers, the layer being compacted by means of embossing calendaring and having highly compacted embossed areas ( 9 ) as well as other areas ( 10 ) which are less compacted in comparison therewith.
Patent EP-1578655-B1 (EP)
Inventor: CATOVIC RADE
IPC: B62D33/067
Filed: 2003-12-18
Granted: 2006-09-27
Abstract: The invention relates to an anti-roll bar 14 which in the suspension of a sprung driver's cab 2 on a vehicle frame 6 connects the cab 2 to the frame 6. The anti-roll bar 14 comprises two shanks 22,23 and at least one reaction rod 20 which are detachably connected together whereby the reaction rod 20 can be disassembled from the shanks 22,23, thereby improving access to the space 19 behind the reaction rod 20 without the fastenings of the anti-roll bar 14 to the cab 2 or to the frame 6 being undone.
Patent EP-1562849-B1 (EP)
Inventor: ROSSIGNOL ERIC
IPC: B66B11/00
Filed: 2003-11-07
Granted: 2006-08-02
Abstract: An elevator monitoring unit and a procedure for maintenance of an elevator monitoring unit include arranging the elevator monitoring unit on at least one door post element which is integrated into the door post, and the door post element is parallel-shifted, to a large extent horizontally, for the purpose of maintenance, repair and diagnostics or is tiltable around a horizontal axis.
Patent EP-1547351-B1 (EP)
Inventor: HANSSON JONAS
IPC: H04M1/72406
Filed: 2003-09-22
Granted: 2007-05-09
Abstract: Method and system for extending and/or modifying functionality of a platform for a product, such as a mobile terminal for a wireless telecommunications system. The system includes a platform domain having a software services component for providing functionality, and an interface component having at least one interface for providing access to the software services component for enabling application software to be installed, loaded and run in said platform via the at least one interface. The system also includes plug-­in software for use together with the application software for extending and/or modifying the functionality of the software services component of the platform domain via the at least one interface.
Patent EP-1552279-B1 (EP)
Inventor: SAGATELYAN DMITRY M
IPC: H04N5/355
Filed: 2003-10-08
Granted: 2008-07-23
Abstract: A photo-detector (122) generated signal (125) is measured as a sample set (192) comprising a long signal and a short signal. The short signal is scaled to the value of the long signal if the long signal exceeds a dynamic range (131) associated with the photo-detector (122). In one embodiment, the short signal is obtained during a short time interval that is at the approximate middle of a long time interval such that the short and long intervals share a common median time value (194). Given such symmetry, an approximately linear signal (190) yields a proportionality parameter between the long and short signals thereby allowing the short signal to be scaled. The proportionality parameter facilitates determination of an integration independent component of the photo-detector signal that should be removed from the measured long and short signals before scaling. A plurality of sample sets (260) can also be processed such that each sample set overlaps with its neighboring sample set, thereby increasing the effective number of sample sets.
Patent EP-1685068-B1 (EP)
Inventor: MANORAMA SUNKARA V
IPC: C01G23/053
Filed: 2003-11-20
Granted: 2009-03-18
Abstract: The present invention relates to an environmentally benign process for the simultaneous preparation of nanocrystalline anatase titanium dioxide and hydrazine monohydrochloride. In particular, the present invention relates to a process for the preparation of nanocrystalline anatase titanium dioxide and hydrazine monohydrochloride by reacting an aqueous solution of titanium tetrachloride taken in concentrated hydrochloric acid with hydrazine monohydrate under constant stirring at ambient temperature and pressure.
Patent EP-1517779-B1 (EP)
Title: Dispositif et procede pour produire des objets tridimensionnels au moyen d'un procede de production generatif
Inventor: HEUGEL MARTIN
IPC: B29C67/00
Filed: 2003-07-11
Granted: 2011-03-02
Abstract: La présente invention concerne un dispositif et un procédé pour produire en couches et de manière générative des objets tridimensionnels. Ce procédé pour produire plusieurs objets parallèlement dans plusieurs chambres de processus (11, 12, 13, 14) consiste à appliquer successivement des couches d'un matériau de construction (25), puis à consolider une couche ou à la relier à la couche précédemment appliquée au moyen d'un rayonnement. Ce rayonnement est conduit d'une source de rayonnement (21) située à l'extérieur des chambres de processus à une partie des chambres de processus, alors qu'une application de couche est effectuée dans l'autre partie des chambres de processus.
Patent EP-1723225-B1 (EP)
Inventor: STROTHOFF WERNER
IPC: C11D7/34
Filed: 2003-12-18
Granted: 2008-05-28
Abstract: The present invention refers to multi-phase tablet for use in a washing machine and/or dishwasher, the tablet comprises at least three phases, whereby a) the first phase comprises an alkalizing agent, whereby the amount of alkalizing agent is sufficient to obtain a washing liquid having a pH-value of 7,5 or more (20 DEG C), b) the second phase comprises an acidifying agent, whereby the amount of acidifying agent is sufficient to obtain a washing liquid having a pH-value of 6,5 or less (20 DEG C), and c) the third phase comprises an alkalizing agent, whereby the amount of alkalizing agent is sufficient to obtain a washing liquid having a pH-value of 7,5 or more (20 DEG C) and to a process of cleaning articles.
Patent EP-1581563-B1 (EP)
Inventor: POLOTTI GIANMARCO
IPC: A61K8/06
Filed: 2003-12-18
Granted: 2006-07-05
Abstract: Disclosed are inverse emulsions useful as thickeners for cosmetic formulations wherein the weight ratio between the aqueous phase and the oil phase is from 4:1 to 2:1 and containing from 20 to 70% by weight of an anionic acrylic polymer obtained by inverse emulsion polymerisation of one or more anionic acrylic monomers, at least one of which containing a strongly acidic functional group, dissolved in the aqueous phase, and at least a hydrophobic acrylic monomer dissolved in the oil phase before the mixing of the two phases. Also disclosed is the procedure for their preparation.
Patent EP-1550044-B1 (EP)
Inventor: PETRIE RICHARD
IPC: H04L12/403
Filed: 2003-10-01
Granted: 2007-03-14
Abstract: L'invention concerne un dispositif destiné à être relié à un hôte pour le transfert de données en série, comprenant un moyen pour transférer à l'hôte une structure de données prédéterminée indiquant si le dispositif prend en charge l'accès direct à la mémoire.
Patent EP-1581509-B1 (EP)
Title: 1-(amino)indanes as edg receptor agonists
Inventor: DOHERTY GEORGE A
IPC: A61K31/397
Filed: 2003-12-16
Granted: 2011-01-19
Abstract: The present invention encompasses compounds of Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.
Patent EP-1684455-B1 (EP)
Inventor: FUKUI NORIYUKI
IPC: H04L1/00
Filed: 2003-11-11
Granted: 2012-06-20
Abstract: 基地局（２）と、その基地局（２）がカバーするサービスエリアに存在する複数の端末（１つの場合を含む）と、を備える通信システムにおいて実現可能な通信方法であって、基地局（２）から受信失敗を示すＮＡＫ信号が返信され、かつ当該ＮＡＫ信号が返信された端末（１）に割り当てられた送信許可時間が終了している場合に、端末（１）が、送信要求を行うことなく自律的に再送データを送信する。
Patent EP-1475119-B1 (EP)
Inventor: PAESCH RAINER
IPC: A61M16/20
Filed: 2004-02-20
Granted: 2006-05-17
Abstract: Device for controlling a gas flow comprises at least one pneumatically controlled amplifier valve (50) arranged together with a dosing device (4) in a valve block (15). Preferred Features: The amplifier valve performs a disconnecting function. The dosing device is designed for hysteresis-free dosing. A pressure regulator (2) is arranged in the region of the valve block. The valve block is designed for connection to a compressed gas bottle for supplying oxygen.
Patent EP-1473872-B1 (EP)
Inventor: TABBARA BASSAM
IPC: H04L69/40
Filed: 2004-04-06
Granted: 2008-07-09
Abstract: Multiple devices are identified in a network along with connection information associated with the multiple devices. The connection information associated with the multiple devices is converted into a hierarchical structure and communication links between the multiple devices are identified.
Patent EP-1492008-B1 (EP)
Inventor: STOCKER THOMAS
IPC: G06F9/445
Filed: 2004-05-27
Granted: 2011-07-13
Abstract: The debugging method uses a diagnosis program (34), installed in the portable data carrier, for detection of faults in an installation routine for the user program (40) to be installed, with transfer of fault information (70) from the installation routine to the diagnosis program. Also included are Independent claims for the following: (a) a portable data carrier; (b) a computer program product containing a user program for a portable data carrier.
Patent EP-1610003-B1 (EP)
Inventor: NEUDERT JAROSLAV
IPC: F15B15/08
Filed: 2004-06-26
Granted: 2007-02-14
Abstract: Door actuator consisting of a double-action pneumatic cylinder consisting of two hollow cases inserted one into the other (1,2), each including a pair of spiral grooves (3) turned by 180 degrees and opposite oriented in the cases (1,2) in relation to each other, and of two pairs of carriers slinding inside the grooves, with both grooves (3) of the inner case (1) in the shape of spatial curves whose tangent and the longitudinal axis of the inner case (1) are in the angle  alpha 1, and both grooves (4) of the outer case (2) in the shape of spatial curves whose tangent and the longitudinal axis of the outer case (2) are in the angle  alpha 2, characterized in that both grooves (4) of the outer case (2) are provided by an extension (5) in comparison to grooves (3) of the inner case (1), in the shape of spatial curves whose tangent and the longitudinal axis of the outer case (2) are in the angle of  alpha 3 in relation to each other. <IMAGE>
Patent EP-1508537-B1 (EP)
Inventor: DAMRATH JOACHIM DR
IPC: B65F1/14
Filed: 2004-08-16
Granted: 2007-08-22
Abstract: A motor (5) drives a pull-out trolley (2). If the motor only operates in one direction , a spring device (9) can be used that moves the pull-out trolley in another direction and is stretched by the motor. This means that moving a refuse container (3) out of a kitchen cupboard (1) inwards and outwards is very conveniently operated. A compacting device compresses refuse in the container. An independent claim is also included for a method for moving a pull-out trolley for a refuse collecting device that holds a refuse container.