baber/WOPTO huggingface dataset:
Patent CA-3041458-A1 (CA)
Inventor: SAMBURSKY ROBERT P
IPC: C12Q1/04
Filed: 2016-10-21
Abstract: Diagnostic devices test markers for viral infection and markers for bacterial infection to effectively assist in the rapid differentiation of viral and bacterial infections, to differentiate between colonization and active infection, and to better diagnose microbiologically unconfirmed patients. In other embodiments, detecting a presence of MxA in combination with either the bacterial biomarker C-reactive protein or the bacterial biomarker procalcitonin increases the specificity of the bacterial biomarker with a concurrent improvement in sensitivity.
Patent CA-3042014-A1 (CA)
Title: Automated unloading and loading robot system
Inventor: BASTIAN WILLIAM
IPC: B25J15/06
Filed: 2017-10-27
Abstract: A system includes a robot configured to load and/or unload from a location, such as a cargo carrier or building. The robot includes a base unit that has a transport system to move the base unit. A mast extends from the base unit, and the mast has a mast conveyor. An End of Arm Tool (EoAT) is coupled to the mast. The EoAT includes an EoAT conveyor configured to move a cargo item to and from the mast conveyor. A gripper mechanism is configured to move between a retracted position where the gripper mechanism is clear of the cargo item on the EoAT conveyor and an extended position where the gripper mechanism is able to grip the cargo item.
Patent CA-3045917-A1 (CA)
Inventor: ZHANG XIAOMING
IPC: A61K31/192
Filed: 2017-12-05
Abstract: The present disclosure provides methods, compositions, devices and systems for dermal and transdermal administration of treprostinil or salts thereof, and optionally an additional therapeutic agent. Treprostinil and salts thereof can be dermally or transdermally administered to treat any medical conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Patent CA-3050899-A1 (CA)
Inventor: CUCHIARA MICHAEL
IPC: A61B18/12
Filed: 2019-07-31
Abstract: Neuromodulation is used to enhance left ventricular relaxation. An exemplary neuromodulation system includes a therapy element positionable in proximity to at least one nerve fiber, and a stimulator configured to energize the therapy element to delivery therapy to the at least one nerve fiber such that left ventricular relaxation and left ventricular contractility are contemporaneously enhanced.
Patent CA-3051866-A1 (CA)
Inventor: SOON-SHIONG PATRICK
IPC: A61P35/00
Filed: 2018-02-01
Abstract: Les compositions et les méthodes envisagées selon l'invention tirent profit d'un ou de plusieurs marqueurs de surface sur une cellule souche cancéreuse qui sont associés à l'auto-protection de cellules tumorales. De tels marqueurs de surface sont spécifiquement ciblés pour guider un traitement du cancer à base de cellules, et en particulier des cellules NK résistantes à l'hypoxie et des agents radiothérapeutiques ciblant directement la cellule souche cancéreuse. De plus, la suppression immunitaire peut être neutralisée à l'aide de divers inhibiteurs, tandis que la réponse immunitaire peut être encore accrue à l'aide de certains agents immunostimulateurs.
Patent CA-3052246-A1 (CA)
Inventor: SAHIN FIKRETTIN
IPC: A61K45/06
Filed: 2018-01-31
Abstract: La présente invention concerne un produit contenant un exosome d'origine végétale qui peut être utilisé dans le traitement du cancer et la cicatrisation des plaies. La présente invention permet d'obtenir un produit à faible coût, qui n'engendre pas d'effets toxiques dans le corps humain, n'occasionne pas de dommages dans les cellules saines au cours du traitement du cancer, ne pose aucun risque d'infection puisqu'il ne nécessite aucune procédure de type radiothérapie ou chirurgie, et où aucun des effets secondaires se produisant dans le traitement par chimiothérapie n'est ressenti. Dans le cadre de l'invention, l'agropyre, l'ail et le gingembre peuvent être utilisés seuls ou en association à titre de source(s) végétale(s).
Patent CA-3052810-A1 (CA)
Inventor: STRUM JAY COPELAND
IPC: C07D517/04
Filed: 2018-02-09
Abstract: La présente invention concerne un modulateur du récepteur des oestrogènes de benzothiophène ou son sel pharmaceutiquement acceptable ou une composition pharmaceutiquement acceptable de celui-ci pour traiter un trouble médical lié aux strogènes.
Patent CA-3055438-A1 (CA)
Inventor: GOLETZ STEFFEN
IPC: C07K16/32
Filed: 2018-03-27
Abstract: The present invention pertains to multispecific antibody constructs directed against the cancer antigen MUC1 and the T cells antigen CD3. In particular, the multispecific antibody constructs recruit T cells to the cancer site. The design of the multispecific antibody constructs show strong antigen binding and high T cell activation.
Patent CA-3056251-A1 (CA)
Inventor: DAWDY DAVID
IPC: E06B9/15
Filed: 2018-03-27
Abstract: A closure may include a door configured to seal an opening. The door may include a section with an internal cavity. The closure may also include a core within a first portion of the internal cavity of the section. The core may be configured to expand from a relaxed state to an expanded state and provide a seal between the door and an edge of the opening when the core is in the expanded state.
Patent CA-3056780-A1 (CA)
Title: Power machine with a boom, a boom actuator, an implement and a stop for preventing contact between the boom actuator and the implement
Inventor: FISER JAROSLAV
IPC: E02F9/22
Filed: 2018-03-23
Abstract: Excavator (400) having a stop (450) positioned on a boom (430) to protect a boom actuator (433B) from damage due to impact with an implement (534) such as a blade, impact with handled material, or impact with other debris or objects. Boom actuators include an override device (605) to allow the boom to be lowered in the event of an accident or component failure.
Patent CA-3057878-A1 (CA)
Title: Steerable foveal display
Inventor: EASH AARON MATTHEW
IPC: G02B7/40
Filed: 2018-03-27
Abstract: A display system comprising a foveal display having a monocular field of view of at least 1 degree is positioned within a scannable field of view of at least 20 degrees, the foveal display positioned for a user. In one embodiment, the foveal display is positioned for the user's fovea.
Patent CA-3059498-A1 (CA)
Title: High brightness projection systems and methods
Inventor: DAMBERG GERWIN
IPC: H01S5/00
Filed: 2018-05-11
Abstract: A hybrid projector architecture combines steered light with unsteered light. In some embodiments the steered light is narrowband light and the unsteered light is broadband light. Splitting between the steered and unsteered light may be determined based on luminance level. For example, the unsteered light may contribute a large proportion of the light for luminance levels up to a threshold. The steered light may contribute an increasing proportion of the light as luminance values rise above the threshold.
Patent CA-3062158-A1 (CA)
Title: Improved extended release highly loaded drug compositions
Inventor: MIINEA LILIANA A
IPC: A61K9/20
Filed: 2018-05-01
Abstract: The disclosed technology provides improved drug compositions that provide increased stability, higher drug loading potential, and suitable drug dissolution properties, and methods of making the same. The composition include: (a) a drug component comprising a therapeutically effective amount of a drug; (b) an extended release component comprising a cross-linked polyacrylic acid polymer that is a carbomer homopolymer, carbomer copolymer, carbomer interpolymer, polycarbophil or a mixture thereof; and (c) a buffering component comprising a magnesium containing buffering agent;  wherein the drug component makes up at least 50% by weight of the composition.
Patent CA-3062665-A1 (CA)
Inventor: KURUVILLA DENNY DEVASIA
IPC: H04N5/262
Filed: 2019-11-26
Abstract: ABRÉGÉ : Un serveur comprend un module de communications, un processeur couplé au module de communications et une mémoire couplée au processeur. La mémoire stocke des instructions pouvant être exécutées par le processeur et qui, une fois exécutées par ce dernier, configurent le processeur pour quil fasse ce qui suit : recevoir un signal représentant une indication dun emplacement de dommage dun véhicule provenant dun appareil informatique à distance par lintermédiaire du module de communications, envoyer des instructions pour obtenir des données vidéo du véhicule daprès lemplacement de dommage provenant dun appareil informatique à distance par lintermédiaire du module de communications, recevoir des données vidéo du véhicule provenant dun appareil informatique à distance par lintermédiaire du module de communications, et traiter les données vidéo pour confirmer une identité du véhicule et pour quantifier numériquement un montant des dommages au véhicule. 42 CA 3062665 2019-11-26
Patent CA-3062991-A1 (CA)
Inventor: GADDE YESWANTH
IPC: A61F13/00
Filed: 2018-05-11
Abstract: L'invention concerne, dans des modes de réalisation, une surveillance tissulaire en combinaison avec des systèmes et des procédés de thérapie de plaie par pression négative. Dans certains modes de réalisation, un système de surveillance et de thérapie comprend la collecte d'images vidéo d'un site tissulaire et l'amplification desdites images vidéo par grossissement vidéo eulérien. En fonction des changements détectés par le grossissement vidéo eulérien, une thérapie de plaie par pression négative peut être administrée au site tissulaire, arrêtée ou modifiée d'une certaine manière.
Patent CA-3066483-A1 (CA)
Title: Pattern angle spatial selection structured illumination imaging
Inventor: NEWMAN PETER CLARKE
IPC: G02B27/42
Filed: 2019-01-14
Abstract: The disclosure provides for structured illumination microscopy (SIM) imaging systems. In one set of implementations, a SIM imaging system may be implemented as a multi-arm SIM imaging system, whereby each arm of the system includes a light emitter and a beam splitter (e.g., a transmissive diffraction grating) having a specific, fixed orientation with respect to the system's optical axis. In a second set of implementations, a SIM imaging system may be implemented as a multiple beam splitter slide SIM imaging system, where one linear motion stage is mounted with multiple beam splitters having a corresponding, fixed orientation with respect to the system's optical axis. In a third set of implementations, a SIM imaging system may be implemented as a pattern angle spatial selection SIM imaging system, whereby a fixed two-dimensional diffraction grating is used in combination with a spatial filter wheel to project one-dimensional fringe patterns on a sample.
Patent CA-3067713-A1 (CA)
Title: Methode de determination du risque de developper un diabete de type 1
Inventor: ZIEGLER ANETTE-G
IPC: C12Q1/6883
Filed: 2018-06-27
Abstract: La présente invention concerne une méthode permettant de déterminer si un sujet présente un risque de développer un diabète de type 1 par détermination du score de risque génétique (GRS) d'un sujet. La présente invention concerne également une composition pharmaceutique comprenant de l'insuline et un support pharmaceutiquement acceptable destiné à être utilisé dans une méthode de prévention du diabète de type 1 chez un sujet ayant un score de risque génétique tel que déterminé par la méthode mentionnée ci-dessus. En outre, l'invention concerne un kit destiné à être utilisé dans une méthode permettant de déterminer si un sujet présente un risque de développer un diabète de type 1 par détermination du score de risque génétique d'un sujet et un antigène du diabète de type 1 destiné à être utilisé dans une méthode d'immunisation d'un sujet contre le diabète de type 1 ayant un score de risque génétique tel que déterminé par la méthode mentionnée ci-dessus.
Patent CA-3068118-A1 (CA)
Title: Underdrain system using one-piece cell dividers
Inventor: GILBERT EMILY
IPC: B01D24/12
Filed: 2018-06-22
Abstract: The present invention is directed to a one-piece cell divider (500) for use in a filter underdrain system that supports a porous plate that supports a filter media for filtering a fluid. The one-piece cell divider (500) includes: a divider portion (510); a porous plate support portion (539), including a flange that supports the porous plate; a support member portion (550), including a flange that attaches the divider (500) to a base. A filter underdrain using a one-piece cell divider may include: at least one porous plate for supporting the filter media for filtering a fluid, the porous plate spanning across at least two of the dividers; the at least two dividers including: one or more one-piece cell dividers; one or more multiple-piece dividers, each multiple-piece cell divider comprising a divider portion and a support member, the support member being directly under the divider portion.
Patent CA-3073503-A1 (CA)
Inventor: WANG QI
IPC: A01N65/28
Filed: 2017-08-28
Abstract: Provided herein are compositions and pharmaceutical compositions comprising .alpha.-terpinolene, terpinen-4-ol, and .alpha.-terpineol. Also provided herein are methods of using such compositions.
Patent CA-3073698-A1 (CA)
Title: Multi-film oil damper with tapered damper rings
Inventor: VEITCH THOMAS
IPC: F01D25/16
Filed: 2020-02-24
Abstract: A multi-film oil damper has a housing defining an annular damper cavity between a radially outward wall and radially extending side walls. The annular damper cavity has an oil inlet configured for connection to a source of pressurized oil. A closure ring defines a radially inward boundary of the annular damper cavity. First and second damper rings are nested together coaxially within the annular damper cavity. At least one of the first damper ring and the second damper ring has an axial end radial thickness less than an intermediate-portion radial thickness.
Patent CA-3076833-A1 (CA)
Inventor: GUNN NICHOLAS MAX
IPC: A61B3/00
Filed: 2018-09-28
Abstract: L'invention concerne un système de détection de pression intraoculaire (PIO), pouvant comprendre un implant de détection de pression intraoculaire à implanter dans l'il d'un patient, destiné à capturer des mesures de pression intraoculaire absolue, et un dispositif externe, destiné à capturer des mesures de pression atmosphérique. L'implant de détection de pression intraoculaire peut être conçu pour capturer une mesure de pression intraoculaire absolue à un instant désigné, et le dispositif externe peut être conçu pour capturer une pluralité de mesures de pression atmosphérique autour de l'instant désigné.
Patent CA-3077537-A1 (CA)
Title: Portable auger-airlock-vacuum
Inventor: HUNDEBY DAVID
IPC: B65G53/14
Filed: 2020-03-31
Abstract: The invention is a portable, auger-airlock-vacuum unit (auger-vac) typically used to auger and vacuum grain but could be used to move other granular products as well. The auger-vac is a unique combination of a portable screw conveyor (auger) and a grain vacuum (vac) where the auger inlet is located to take in grain directly from a grain pile and the discharge end of the auger is located over the truck, bin or trailer to be loaded. The suction hose of the vac is typically located in the proximity of the auger inlet and is also engaged in the grain pile. Grain is enters the suction hose and flows into the separator chamber. The grain then moves through an airlock and drops into the tube of the auger. This vacuumed grain is then carried up the auger tube by the auger screw, along with the grain taken in at the auger inlet, and the sum of grain is discharged close to the upper end of the auger tube. The auger-vac has the full capacity of a typical portable granular conveyor plus the added capacity and convenience of a grain vacuum to help clean up the floor of a flat-bottomed bin.
Patent CA-3078490-A1 (CA)
Title: Distribution cabling tape, system and tape application device
Inventor: BORER VICTOR JULIAN
IPC: G02B6/44
Filed: 2018-10-03
Abstract: A distribution cabling tape system comprises a resilient polymeric base sheet having a first major surface and a second major surface, the first major surface being substantially continuous across a side to side width, an adhesive layer disposed on the first major surface, the adhesive layer capable of adhering to a concrete or asphalt surface, and first and second spacer layers arranged in a spaced apart configuration on the adhesive layer to form a continuous lengthwise channel configured to receive at least a portion of at least one distribution cable, each of the first and second spacer layers comprising a second adhesive layer disposed thereon, the second adhesive capable of adhering to a concrete or asphalt surface.
Patent CA-3080600-A1 (CA)
Inventor: BURTON DAVID
IPC: A61B5/398
Filed: 2016-01-06
Abstract: An apparatus for determining and monitoring neurological or muscular disorder, comprising of: sensors for acquiring electro-myographic (EMG) signals of a subject; wherein the EMG  signals are used to determine REM stages of sleep; and wherein the EMG signals are used to determine the presence of atonia; and the EMG signals are used to determine the presence of REM sleep behavior disorder (such as Parkinson's, restless leg, leg movement syndrome, dystonia, Wilson's disease, Huntington, Alzheimer or the like) and the sensors are for determining the electroencephalographic (EEG) signals of subject, or they further comprising determining elecro-oculogram (EOG) signals or motion signals. The apparatus is also used in monitoring muscular disorder that is a Parkinson's disease's disorders.
Patent CA-3081161-A1 (CA)
Inventor: TOV NAVEH
IPC: A61P11/00
Filed: 2018-10-29
Abstract: The present invention discloses methods for preventing or reducing lung injury associated with lung transplantation in lung transplant recipients. The method of the invention comprises the administration of improved dosage regimen of Alpha-1 Antitrypsin (AAT) for prevention of acute and/or chronic refractory rejection in lung transplant patients.
Patent CA-3083667-A1 (CA)
Inventor: MIETHIG WERNER
IPC: B60R1/06
Filed: 2018-12-11
Abstract: The invention relates to a camera arm (100) of a camera-based mirror substitute system for a motor vehicle, the arm having a first structural element (110) for connecting the camera arm (100) to a motor vehicle and a second structural element (120) which has at least one camera (180), the second structural element (120) being pivotable in relation to the first structural element (110). In order to provide a fixation system for cameras of camera-monitor systems acting as mirror substitutes in motor vehicles, which offers improved protection against external damage to the fixation and to all elements, devices and modules located thereon, in particular to cameras, and which allows the camera to have an optimal image range, according to the invention the second structural element (120) and the first structural element (110) are connected via a pivoting mechanism (150), said pivoting mechanism having a planetary gear (151).
Patent CA-3084623-A1 (CA)
Inventor: MASCARELLO ALESSANDRA
IPC: A61P25/00
Filed: 2018-12-14
Abstract: La présente invention concerne la 3-(2-(4-(2-méthoxyphényl) pipérazine-1-yl) éthyl) quinazoline-4(3H)-one, des sels pharmaceutiquement acceptables, des énantiomères, des diastéroisomères, des stéréoisomères, des cristaux, des hydrates, des solvates, des promédicaments et des métabolites de ceux-ci pour le traitement d'un trouble du syndrome post-traumatique (TSPT), et des compositions pharmaceutiques contenant les composés pour le traitement d'un trouble du syndrome post-traumatique (TSPT).
Patent CA-3086922-A1 (CA)
Inventor: GEBERT SHELLY
IPC: A01N63/20
Filed: 2018-12-27
Abstract: The present inventors disclose new fermentate compositions that display antimicrobial activity against a variety of microorganisms in foods. The fermentate compositions may not only be active at acidic pHs, but also retain antimicrobial activity at elevated pHs including neutral pHs. In addition to new fermentate compositions, the present invention also relates to improved methods for making such fermentate compositions and using unpurified fermentate compositions to effectively preserve food products.
Patent CA-3091349-A1 (CA)
Inventor: GHANEI HAMID
IPC: A47C27/14
Filed: 2019-02-21
Abstract: A support cushion (10) for providing air flow to a user resting on the support cushion is provided. The support cushion includes pocketed coil layer (40) and a base layer (30) positioned adjacent to and below the pocketed coil layer. The pocketed coil layer including a plurality of fabric types for directing air flow. A fan (50) is operably connected to the inlet hole of the base layer to provide air flow into and through the pocketed coil layer to a body support layer. Methods of controlling air flow through a support cushion are also provided.
Patent CA-3092966-A1 (CA)
Title: Systeme et methode de traitement d'une dysfonction des glandes de meibomius
Inventor: SULLIVAN DAVID A
IPC: A61F9/007
Filed: 2019-02-28
Abstract: L'invention concerne des systèmes et des méthodes de traitement d'une dysfonction des glandes de Meibomius et sébacées. Les méthodes comprennent la réduction de la concentration d'oxygène dans l'environnement d'une ou de plusieurs glandes de Meibomius et sébacées dysfonctionnelles, pour restaurer ainsi l'état hypoxique de ladite ou desdites glandes de Meibomius et sébacées dysfonctionnelles. La réduction de la concentration d'oxygène s'obtient par restriction de la circulation sanguine à destination de la ou des glandes de Meibomius et sébacées dysfonctionnelles et de leur environnement. La restriction de la circulation sanguine s'obtient par contraction ou fermeture d'un ou plusieurs vaisseaux sanguins autour de la ou des glandes de Meibomius et sébacées dysfonctionnelles. Les méthodes comprennent également l'administration de médicaments à usage local ou systémique qui conduisent à la génération de facteurs inductibles par hypoxie dans une ou plusieurs glandes de Meibomius et sébacées dysfonctionnelles.
Patent CA-3093603-A1 (CA)
Title: Cd47 blockade therapy and cd38 antibody
Inventor: LIN GLORIA HOI YING
IPC: C07K16/28
Filed: 2019-03-08
Abstract: CD47+ disease cells such as cancer cells are treated using a combination of CD47 blocking agent and a CD38 antibody such as daratumumab. The anti-cancer effect of SIRPaFc is enhanced in the presence of daratumumab. Specific combinations include SIRPaFc forms that comprise an Fc that is either IgG1 or IgG4 isotype. These combinations are useful particularly to treat blood cancers including lymphomas, leukemias and myelomas.
Patent CA-3094383-A1 (CA)
Title: Pavement repair system
Inventor: COE WILLIAM B
IPC: E01C23/10
Filed: 2014-03-13
Abstract: PAVEMENT REPAIR SYSTEM ABSTRACT OF THE DISCLOSURE A pavement repair system is provided utili7ing solid phase auto regenerative cohesion and homogenization by liquid asphalt oligopolymerization technologies. The system is suitable for use in repairing asphalt pavement, including pavement exhibiting a high degree of deterioration (as manifested in the presence of potholes, cracks, ruts, or the like) as well as pavement that has been subject to previous repair and may comprise a substantial amount of dirt and other debris (e.g., chipped road paint or other damaged or disturbed surfacing materials). A system utilizing homogenization by liquid asphalt oligopolymerization is suitable for rejuvenating or repairing aged asphalt, thereby improving properties of the paving material. Date Recue/Date Received 2020-09-24