baber/WOPTO huggingface dataset:
Patent SG-11201811595S-A (SG)
Title: Liponucleotide-based therapy for ards
Inventor: DAVIS IAN
IPC: A61K31/70
Filed: 2017-06-27
Abstract: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property MD HIM 0 11101 HOE 3E1 0 0111101111110111101010 111111111011011# Organization International Bureau (10) International Publication Number (43) International Publication Date ......0\"\" WO 2018/005527 Al 04 January 2018 (04.01.2018) WIP0 I PCT (51) International Patent Classification: A61K 31/513 (2006.01) A61K 31/70 (21) International Application Number: (22) International Filing Date: 27 June 2017 (25) Filing Language: (26) Publication Language: (30) Priority Data: 62/355,096 27 June 2016 (27.06.2016) (71) Applicant: OHIO STATE INNOVATION DATION [US/US]; 1524 North High Street, OH 43201 (US). (72) Inventor: DAVIS, Ian, Christopher; 5608 ye, Hilliard, OH 43026 (US). (74) Agent: GILES, P. Brian Giles; Thomas 3200 Windy Hill Road, Suite 1600E, Atlanta, PCT/US2017/039545 HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, (2006.01) KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (27.06.2017) (84) Designated States (unless otherwise indicated, for every English kind of regional protection available): ARIPO (BW, GH, English GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, US EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, FOUN- TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, Columbus, KM, ML, MR, NE, SN, TD, TG). Hardwell Dri- Declarations under Rule 4.17: — as to applicant's entitlement to apply for and be granted a patent (Rule 4.1700) Horstemeyer LLP, — as to the applicant's entitlement to claim the priority of the GA 30339 earlier application (Rule 4.17(iii)) — of inventorship (Rule 4.17(iv)) for every Published: AG, AL, AM, — with international search report (Art. 21(3)) BR, BW, BY, BZ, DJ, DK, DM, DO, GM, GT, HN, (US). = (81) Designated States (unless otherwise indicated, = kind of national protection available): AE, _ AO, AT, AU, AZ, BA, BB, BG, BH, BN, CA, CH, CL, CN, CO, CR, CU, CZ, DE, = DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, (54) Title: LIPONUCLEOTIDE-BASED THERAPY FOR ARDS - ... .. - .. ... I I , . . • I 1 I = 2 = = = — E` ) = c . ci = 8 = 1 = _ = 0 = 12_ 0_ 0 1-1 IN 0 N kl) kl) 0 0 -.... 00 C (57) : Compositions and method are \" tains one, two, or more cytidine diphosphate (CDP)-conjugated precursors selected from the group consisting of CDP-choline, CDP- ,., ethanolamine, and CDP-diacylglycerol (CDP-DAG) 2 MOCK 2 6 MOCK 6 FIGURE 1 therefore disclosed for treating ARDS. In particular, disclosed a composition that con- in a pharmaceutically acceptable carrier for use in treating ARDS.
Patent AT-386620-B (AT)
Title: Apparatus for the production of a yarn
IPC: D01H1/11
Filed: 1987-03-05
Granted: 1988-09-26
Abstract: The fibre feed device for the spinning gusset 4 between two codirectionally rotating spinning drums 1, 2 lying closely next to one another consists of a feeder roller 8 which precedes one spinning drum 1 and which has a suction-exposed circumferential region 12 leading into the spinning gusset 4 and, on the spinning-drum side, axially next to the suction-exposed circumferential region 12, a blowing zone 15 which is followed by a fibre guide duct 21 projecting into the spinning gusset 4. In order to achieve fibre orientation in the longitudinal direction of the spinning gusset 4, the fibre guide duct 21 consists of a transition elbow 22 which is located on the blowing-zone side and which has adjoining it a portion 23 running essentially symmetrically to the mid- plane between the two spinning drums 1 and 2. <IMAGE>
Patent AT-402068-B (AT)
Title: Fire-resistant coating
IPC: C04B20/00
Filed: 1995-04-10
Granted: 1997-01-27
Abstract: A fire-resistant coating contains a mixture of natural cork granules and vermiculite granules in a ratio of 1:3 as filler and a binder. The filler additionally contains titanium oxide as additive. The binder is a combination of at least one high molecular weight binder based on a synthetic polymer and at least one water-soluble binder having a mineral basis. Owing to the cells in the natural cork expanding under the action of heat, the insulating action and fire resistance are increased. The vermiculite particles, which likewise expand, protect the natural cork from excessive thermal stress, so that not only a good fire resistance capability but also a good fire resistance time are obtained. For the fire resistance class L30, the coating has a thickness of about 10 mm, for the fire resistance class L60 it has a thickness of about 13 mm and for the fire resistance class L90 it has a thickness of about 16 mm.
Patent DK-164492-B (DK)
Title: Cyclone separator and method for separation of a three- phase mixture
Inventor: COLMAN DEREK ALAN
IPC: B04C/
Filed: 1987-02-13
Abstract: PCT No. PCT/AU86/00174 Sec. 371 Date Mar. 2, 1987 Sec. 102(e) Date Mar. 2, 1987 PCT Filed Jun. 17, 1986 PCT Pub. No. WO86/07549 PCT Pub. Date Dec. 31, 1986.This invention is about a cyclone separator, and may be applied to the cyclone separators disclosed and claimed in UK Pat. Nos. 1583742, 1583730 or 2102311, or those described in UK Patent Application 8419771 or 8511149 or 8515264. Thus, application 8419771 describes a cyclone separator which has an inlet portion having generally the form of a volume of revolution with a single tangential inlet (preferably with an involute feed channel, for introducing feed to be separated into the cyclone separator and, adjacent to the inlet portion and substantially coaxial therewith, a generally axially symmetrical separation portion converging uninterruptedly into a downstream portion. The inlet portion has an axial overflow outlet opposite the separation portion (i.e. in its end wall). The involute feed channell may be fed from a duct directed tangentially into the inlet portion, the (outer) wall of the channel converging to the principal diameter of the inlet portion, preferably by substantially equal radial decrements per unit angle around the axis, preferably attaining the principal diameter after 360 DEG around the axis.
Patent HU-184767-B (HU)
Title: Process for the production of prostacycline-analogues and of pharmaceutical preparations containing them as active substance
Inventor: BARTMANN WILHELM
IPC: C07D307/937
Filed: 1980-01-24
Abstract: What is disclosed are prostacyclin analogs of the general formula I <IMAGE>  I  which have a more specific action and/or a longer action than the naturally occurring prostacyclin PGI2, as well as intermediate products for their preparation and a process for their preparation. The compounds of formula I are distinguished by inhibitory action on thrombocyte aggregation and by relaxation of the vascular walls, in particular of the coronary arteries. They can thus be used as medicaments.
Patent HU-201803-B (HU)
Title: Process for producing polypeptides forming the agent of anti-malaria vaccine
Inventor: GROSS MITCHELL STUART
IPC: C12R1/19
Filed: 1986-02-06
Abstract: A vaccine for protecting mammals against malaria is prepared by a process comprising inserting a coding sequence for all or a portion of the repeat unit of the CS protein of Plasmodium falciparum into an E. coli expression vector such that the coding sequence is operatively linked to a regulatory element, culturing the transformed E. coli such that the polypeptide is produced and purifying the polypeptide therefrom.
Patent HU-189563-B (HU)
Title: Process for preparing ester derivatives of cyclopropane-carboxylic acid further insecticide compositions containing such compounds
Inventor: NEZOT FRANCOIS
IPC: C07D277/20
Filed: 1982-02-25
Abstract: Novel esters of the formula    <IMAGE>  I  wherein R is selected from the group consisting of   <IMAGE>  W is selected from the group consisting of hydrogen and -CN, Z is selected from the group consisting of -CH2- and -O-, and is attached to a carbon atom included between a nitrogen and the sulfur atom of Y and Y is selected from the group consisting of thiazolyl or thiadiazolyl connected to   <IMAGE>  at one of its available positions.
Patent RS-49570-B (RS)
Title: Improved vapor-pemeable shoe
Inventor: POLEGATO MARIO
IPC: A43B17/08
Filed: 1998-05-08
Abstract: A vapor-permeable shoe comprising:     a vapor-permeable upper (711);   a tread sole (713); a mid-sole, which comprises at least one membrane (715) made of waterproof and vapor-permeable material;   a vapor-permeable or perforated insole (717); and a vapor-permeable or perforated filler layer (719) which is arranged between said insole (717) and said membrane (715); whereby the tread sole (713) is a composite having a lower tough and waterproof layer (713a) which is in contact with the ground during use and an upper region having a layer (713b) permeable to heat and moisture which faces the membrane (715) upon assembly, and the permeable layer (713b) allowing transpiration through its perimetric edge in contact with the outside.   <IMAGE>
Patent YU-49123-B (YU)
Inventor: CHIU K CHARLES
IPC: A61P5/32
Filed: 1996-11-01
Abstract: Postupak za dobijanje (-)Cis-6(S)-Fenil-5(R)[4-(2-pirolidin-1-il etoksi)fenil]-5,6,7,8-tetrahidronaftalen-2-ol D-tartarata, naznačen time, što obuhvata: a) rastvaranje racemata ili parcijalno optički obogaćenog cis-6-fenil-5[4-(2-pirolidin-1-il-etoksi)fenil]-5,6,7,8-tetrahidronaftalen-2-ol u ključalom vodenom etanolu radi stvaranja rastvora; b) dodavanje iste molarne količine D-vinske kiseline rastvorene u vodenom etanolu u navedeni rastvor radi dobijanja drugog rastvora; c) hlađenje navedenog drugog rastvora; i d) skupljanje proizvoda dobijenog u prethodnoj fazi.
Patent ZA-88744-B (ZA)
Title: A system for introducing additive into a container
IPC: B44D3/06
Filed: 1988-02-02
Abstract: A system for introducing a flowable additive (3) from a capsule (1) to paint (4), varnish, woodstain or the like in a closed (preferably lidded) container (2)(for example a paint container) modified by the provision of a relatively easily openable inlet (9) into the container. Preferably the inlet is located in a lid (6). The Capsule comprises a chamber (23) which defines a volume which contains the additive. The system is provided with means (25 and 34) for creating an opening in the chamber which can communicate with the inlet and means (preferably a compressible chamber) for positively expelling additive through the opening by contracting the volume which contains the additive. The capsule and container are also provided with co-operable locating means (10 and 30 with 25) which can co-operate to assist in locating the opening created in the chamber in communication with the inlet. Also a capsule and a closed container for use in the system and a method of introducing additive using the system. Use of the system reduces the risk of spillage and splashing and permits more controlled tinting of paint and therefore is more suitable for use by inexperienced people.
Patent ZA-89293-B (ZA)
Title: Sulfurized compositions,and additive concentrates and lubricating oils containing same
Inventor: SCHROECK CALVIN W
IPC: C10N40/08
Filed: 1989-01-13
Abstract: Sulfurized mixtures which include (A) at least one partial fatty acid ester of a polyhydric alcohol, and (B) at least one member of the group consisting of (1) at least one fatty acid ester of a polyhydric alcohol, which fatty acid ester is different from the partial ester (A), (2) at least one fatty acid, (3) at least one olefin, and (4) at least one fatty acid ester of a monohydric alcohol. The sulfurized compositions are useful in preparing additive concentrates and lubricating compositions.
Patent ZA-89986-B (ZA)
Title: 3-alkenyl-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid compounds
Inventor: MURATA MASAYOSHI
IPC: C07D477/00
Filed: 1989-02-08
Abstract: A compound of the formula : <CHEM>  in which R<1> is carboxy or protected carboxy,  R<2> is hydroxy(lower)alkyl or protected hydroxy(lower)alkyl,  R<3> and R<4> are each hydrogen or lower alkyl, and R<5> is aliphatic heterocyclic group, which may be substituted by suitable substituent(s), and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions comprising them as an active ingredient in admixture with a pharmaceutically acceptable carrier or excipient.
Patent AT-392791-B (AT)
Title: Process for the preparation of 1-substituted aryl-1,4- dihydro-4-oxonaphthyridine derivatives
IPC: C07D471/04
Filed: 1989-08-24
Granted: 1991-06-10
Abstract: The invention relates to a process for the industrial preparation of a 1-substituted 1,4-dihydro-4- oxonaphthyridine derivative and a salt thereof, each of which can be used as intermediates for preparing an antibacterial agent.
Patent AT-400194-B (AT)
Title: Heating boiler with a burner
IPC: F24H9/18
Filed: 1993-11-08
Granted: 1995-10-25
Abstract: Heating boiler with a burner, with a heat exchanger 19, with exhaust-gas ducting and with a heat-insulating housing which is clad on the front side with a casing plate 9, the casing plate 9 having a recess 13 for pushing in the burner fastened to a burner plate 8. In order, in a heating boiler of this type, to suppress the conduction of heat to the outer appliance cladding via the casing plate 9, without having to take into account adverse effects on the stability of the components of the appliance, there is provision for the edge of the recess 13 to be spaced a few millimetres from the burner plate 8 on all sides, clamping elements 16a/16b for connecting the burner plate 8 to the casing plate 9 being provided. <IMAGE>
Patent AT-387056-B (AT)
Title: Free-play anchor
IPC: E02D5/80
Filed: 1985-08-26
Granted: 1988-11-25
Abstract: In a free-play anchor, the tendons 1 are surrounded over the entire free prestressing length by a casing tube 20, it being possible for the free space between tendons 1 and casing tube 20 to be filled. The casing tube 20 is surrounded at a slight distance by a sliding tube 21 which is essentially the same length and is held in a fixed position in the drill hole 15. The space between casing tube 20 and sliding tube 21 contains no sealing or filling material whatsoever. The tendons 1 can therefore be displaced together with the casing tube 20 relative to the fixed sliding tube 21; i.e. it is possible at any time to subsequently tension and slacken the tendons and check the tensile stress present in the tendons. <IMAGE>
Patent DK-154091-B (DK)
Inventor: KUNG PATRICK CHUNG-SHU
IPC: C12N15/00
Filed: 1980-12-03
Abstract: Hybrid cell line for production of monoclonal antibody to an antigen found on normal human suppressor T cells. The hybrid is formed by fusing splenocytes from immunized CAF<sub>1</sub> mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.
Patent DK-158745-B (DK)
Title: Continuous interesterification process using a lipase enzyme as the interesterification catalyst
Inventor: MACRAE ALASDAIR ROBIN
IPC: C11C3/10
Filed: 1983-12-29
Abstract: In a continuous interesterification process a fatty acid ester reactant, preferably a glyceride and optionally including free fatty acid, is contacted with an enzyme as interesterification catalyst which is preferably 1,3-selective and precipitated on an inert particulate support. The catalyst is packed in a fixed bed with contact times less than 2 hours which are sufficient to effect interesterification. The process is useful for producing POSt- and StOSt-rich fats suitable for use as cocoabutter substitute fats.
Patent FI-83579-B (FI)
Inventor: THALER BARRY JAY
IPC: H01F41/04
Filed: 1986-05-02
Granted: 1991-04-15
Abstract: A high voltage transformer for a video display apparatus includes a bobbin-wound tertiary winding. The bobbin incorporates integral nonmetallic terminal posts about which the winding segment wire is wound and terminated. The winding segments are interconnected by electrical components. The component leads incorporate a solder coating and are flattened to provide a large bonding area with the wire on the terminal posts. The component lead overlays the winding segment wire and is joined thereto by a fusion bonding process. The fusion bonding removes the wire insulations and melts the component lead solder coating to form a reflow solder joint.
Patent FI-92359-B (FI)
Inventor: TASTO MANFRED
IPC: H04L7/033
Filed: 1987-08-05
Granted: 1994-07-15
Abstract: For synchronizing a data block in a receiver, there are transmitted consecutively and prior to the data block: a first bit sequence of alternating "0" and "1" levels for determining the bit clock and a second bit sequence for determining the block synchronization by correlation. In known methods of determining the bit clock, the phase range of the individual bits of the received digital signal is divided into sub-intervals and the phase position of the bit clock is determined on account of the number of edges in these sub-intervals. In order to avoid fading and phase jitter having a detrimental effect on the bit synchronism, more specifically when transmitting through radio transmission links, N-phase-shifted clocks having the same clock frequency are generated in the receiver by means of which the first bit sequence is sampled. The clock for which the number of sample-value changes of the first bit sequence is established as having a predeterminable minimum value during a predeterminable time-interval is utilized as the phase synchronous bit clock.
Patent FI-86747-B (FI)
Inventor: RAINGER CHARLES W
IPC: C22C38/42
Filed: 1987-08-21
Granted: 1992-06-30
Abstract: A highly pitting residual duplex stainless steel alloy is provided which comprises, in weight percentage, C: 0.10% and below; Si: 1.5% and below; Mn: 2.0% and below; Cr: 25.0% to 27.0%; Ni: 5.0% to 7.5%; Cu: 1.5% to 3.5%; N: 0.15% and below; Mo: 0.5% and below; and the remaining portion being substantially Fe to form the material of the highly pitting resistant duplex stainless steel alloy.
Patent FI-104068-B (FI)
Inventor: IKEDA TAKAFUMI
IPC: A61K31/40
Filed: 1993-07-22
Granted: 1999-11-15
Abstract: Certain novel indoline derivatives having the ability to inhibit the 5-lipoxygenase enzyme and having formula (I) wherein R1 is C1-C4 alkyl or -NR2R3; R2 and R3 are each, independently, hydrogen or C1-C4 alkyl; R4 is C3-C6 cycloalkyl, C4-C7 cycloalkylalkyl, aryloxy C2-C4 alkyl,  arylthio C2-C4 alkyl, arylamino C2-C4 alkyl, arylsulfinyl C2-C4 alkyl, aryl, aryl C1-C6 alkyl, aryloxyaryl C1-C6 alkyl or arylthioaryl C1-C6 alkyl, and the aryl groups in the said aryloxyalkyl, arylthioalkyl, arylaminoalkyl, arylsulfinylalkyl, aryl, arylalkyl, aryloxyarylalkyl and arylthioarylalkyl may be substituted up to the maximal number of substituents and the substituents are each independently, selected from the group consisting of halo, cyano, C1-C5 alkyl, C2-C6 alkenyl, C1-C5 alkoxy, C2-C6 alkenyloxy, C2-C6 alkoxyalkyl, halosubstituted C1-C4 alkyl, halosubstituted C1-C4 alkoxy, C2-C5 alkoxycarbonyl, aminocarbonyl and C1-C4 alkylthio; A is C1-C6 alkylene, C3-C6 alkenylene or -O-(CH2)m-; Y is each independently, halogen, halosubstituted C1-C6 alkyl, C1-C6 alkyl, C2-C6 alkenyl, C1-C6 alkoxy or C3-C8 alkenyloxy;  m is 2, 3 or 4; n is 0, 1, 2 or 3; and provided that the substituent Y, if present, and the linking group A are attached to the aromatic ring. These compounds are useful in the treatment of alleviation of inflammatory diseases, allergic conditions and cardiovascular diseases in mammals and as the active ingredient in pharmaceutical compositions for treating such conditions.
Patent FI-104968-B (FI)
Title: Process for the preparation of novel therapeutically active substituted imidazole derivatives
Inventor: KARJALAINEN ARTO JOHANNES
IPC: A61K31/415
Filed: 1994-06-16
Granted: 2000-05-15
Abstract: PCT No. PCT/FI92/00349 Sec. 371 Date Sep. 19, 1994 Sec. 102(e) Date Sep. 19, 1994 PCT Filed Dec. 18, 1992 PCT Pub. No. WO93/13074 PCT Pub. Date Jul. 8, 1993.The invention provides compounds of the formula    <IMAGE>  I  wherein Y is -CH2- or -CO-; R1 is F, Cl or OH; R2 is H, F or Cl; and R3 is H, CH3 or CH2CH3, excluding 4-(5-chloro-2,3-dihydro-1H-inden-2-yl)-1H-imidazole and 4-(4-chloro-2,3-dihydro-1H-inden-2-yl)-1H-imidazole; and their non-toxic acid addition salts and mixtures thereof. Processes for the preparation of these compounds are described, as are pharmaceutical compositions comprising at least one of the compounds or its salt. The compounds and their non-toxic salts exhibit valuable pharmacological activity and are highly selective and long acting antagonists at  alpha 2-adrenoceptors. Their peroral bioavailability is good. The compounds are especially useful in the treatment of cognitive disorders.
Patent FI-108726-B (FI)
Inventor: STEINER GERD
IPC: C07D409/14
Filed: 1994-12-19
Granted: 2002-03-15
Abstract: PCT No. PCT/EP93/01438 Sec. 371 Date Dec. 16, 1994 Sec. 102(e) Date Dec. 16, 1994 PCT Filed Jun. 8, 1993 PCT Pub. No. WO94/00458 PCT Pub. Date Jan. 6, 1994.Abstract of the Disclosure: Compounds of the formula I    <IMAGE>  I  where R1, R2, n , R3, A, X, Y and Z have the meanings stated in the description, and the preparation thereof are described. The novel compounds are suitable for controlling diseases , i.e., as neuroleptics, antidepressants, sedatives, hypnotics, CNS protectives or muscle relaxants.
Patent FI-106566-B (FI)
Inventor: MAEKIPIRTTI SIMO
IPC: D04H1/54
Filed: 1998-06-12
Granted: 2001-02-28
Abstract: The new method combination is aimed at improving and regulating the adhesion between similar or different fibers in connection with a method for producing hydroentangled and thermobonded fabrics from cellulose and synthetic fiber blends. Improvement of the fiber adhesion aims at providing highstrength and well absorbing, stable, non-linting nonwoven structures containing high cellulose concentrations. In the new method, adhesion strength is improved by increasing kinetically and quantitatively the contact and wetting between molten polyolefin used for cellulose bonding, and the cellulose, and providing in the cooling contact site transcrystallization following heterogenous nucleation of the polyolefin structure. In order to provide for pre-contacts between the cellulose and cellulose-polyolefin fibers, effectivated hydrogen bonding between the cellulose fibers is used, especially when mechanically hydroentangling cellulose using unreacting synthetic fiber (polyamide, ester). In order to improve adhesion strength, the surface structure of the polyolefin and/or cellulose fibers has to be modified. The surface structure of the polyolefins is modified by molecular chain degradation caused by spinning oxidation, in order to decrease the surface energy, viscosity and temperature of the surface melt formed in bonding. The modification of the cellulose surfaces takes place by heat treatment in a polar liquid, whereby in connection with a conversion of the cellulose crystal structure (C-II (C-I) -> C-IV), its surface energy, crystallinity degree and crystal lamellar thickness of its superstructure increase. Hydrogen bond formation is activated with a combined corona and steam wetting-pressure-drying method.