baber/WOPTO huggingface dataset:
Patent ES-2187095-T3 (ES)
Inventor: BELLER MATTHIAS PROF
IPC: C07C235/00
Filed: 1999-05-03
Granted: 2003-05-16
Abstract: Preparation of N-acyl aminoacids (I) involves reacting a nitrile with an aldehyde in the presence of an acid, carbon monoxide and a metal catalyst. Preparation of N-acyl protected aminoacids of formula (I) involves reacting a nitrile of formula R'CN (II) with an aldehyde of formula RCHO (III) (optionally in trimer or oligomer form) in the presence of an acid, carbon monoxide and a metal catalyst. R = H, COOH, 1-12C linear, branched or cyclic alkyl, 2-12C linear, branched or cyclic, mono- or polyunsaturated alkenyl, 1-8C acyloxy or 5-18C aryl; and R' = H, 1-26C linear, branched or cyclic alkyl, 2-24C linear, branched or cyclic, mono- or polyunsaturated alkenyl, (6-18C) alkyl-(5-18C) aryl or mono- or polyunsaturated (2-10C) alkenyl-(5-18C) aryl.
Patent ES-2213312-T3 (ES)
Title: Procedimiento de regulacion de un aparato frigorifico.
Inventor: JOKSCH HARALD DIPL-ING
IPC: F25D11/02
Filed: 1999-05-18
Granted: 2004-08-16
Abstract: LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA CONTROL DE UN APARATO FRIGORIFICO CON AL MENOS DOS COMPARTIMENTOS SEPARADOS UNO DE OTRO TERMICAMENTE CON TEMPERATURA DIFERENTE Y CON UN COMPRESOR, QUE ALIMENTA AL MENOS A DOS EVAPORADORES CON MEDIO FRIGORIFICO, DISPUESTOS UNO DETRAS DE OTRO EN CONEXION EN SERIE, QUE SIRVE PARA LA REFRIGERACION DE LOS COMPARTIMENTOS FRIGORIFICOS Y QUE ESTA CONTROLADO CON UN ELEMENTO DE REGULACION DISPUESTO EN UN COMPARTIMENTO DE TEMPERATURA MAS ALTA PARA MANTENIMIENTO DE LAS TEMPERATURAS DE COMPARTIMENTO DE ACUERDO CON UNA DETERMINACION PREVIA. LA TEMPERATURA DE COMPARTIMENTO EN EL COMPARTIMENTO DE TEMPERATURA MAS ALTA PUEDE SER INFLUENCIADA POR UN ELEMENTO DE CALENTAMIENTO, HABIENDOSE PREVISTO UNA UNIDAD DE CONTROL ELECTRONICA, QUE REGISTRA LA TEMPERATURA DE COMPARTIMENTO POR MEDIO AL MENOS DE UN SENSOR DE TEMPERATURA EN EL COMPARTIMENTO DE TEMPERATURA MAS BAJA Y LA COMPARA CON UNA TEMPERATURA TEORICA ALMACENADA EN UNA MEMORIA DE DATOS Y EN CASO DE QUE SE ENCUENTRE POR DEBAJO O POR ENCIMA DE LA TEMPERATURA TEORICA ACORTA O ALARGA LA RELACION DE CALENTAMIENTO DEL EQUIPO DE CALENTAMIENTO.
Patent ES-2242380-T3 (ES)
Inventor: ROSS JAMES CAMERON
IPC: E04D12/00
Filed: 1999-02-09
Granted: 2005-11-01
Abstract: A sheet metal exterior sheathing element particularly suitable as a roofing tile. The tile has inter-engageable channels on its opposing longitudinal sides, one channel (6, 7) being on the underside and the channel (9) on the upperside of the tile. A mounting tab (10) extends from adjacent the upperside channel (9) substantially co-planar to the body of the tile. The channels enable two tiles (1a, 1b) to be joined in an overlapping side by side relationship with their corresponding channel sections engaged. Each tile (1a, 1b) can be fixed to a supporting structure by their mounting tabs (10). A third tile (1c) can then be joined longitudinally of the first two tiles (1a, 1b) by engaging its underside channel (6) over and about their joined upperside channel sections (9). It can also be fixed to the supporting structure and the steps repeated to sheath a desired area.
Patent ES-2247786-T3 (ES)
Inventor: WAGNER TORSTEN
IPC: A61K31/5585
Filed: 1999-02-24
Granted: 2006-03-01
Abstract: A process for the production of encased, spherical granular grains comprising spraying grains which consist of a prostane derivative and a cyclodextrin vehicle, forming together a prostane-cyclodextrine-clathrate, with an aqueous polymer dispersion of ethyl cellulose and/or poly(methyl)acrylic acid ester in a fluidized or boiling bed is disclosed. The polymer dispersion is applied in a thickness equivalent to 1-5% (w/w) of the total mass of the encased grains. The coated grains are cured for at least 24 hours. Grains produced according to this method have a pharmaceutical active ingredient release profile which remains unchanged over the storage time.
Patent ES-2219003-T3 (ES)
Inventor: BAUR FRANZ
IPC: F16B7/08
Filed: 1999-02-18
Granted: 2004-11-16
Abstract: In order to provide a connecting means for the releasable connection of a first component and a second component, in particular, for the releasable connection of furniture and machine parts, comprising a first connecting element arranged on the first component and a second connecting element arranged on the second component, wherein the first connecting element and the second connecting element are releasably connected to one another in the connected state of the components and one of the connecting elements comprises a retaining part which interacts with the other one of the connecting elements in a retaining position such that any relative movement of the first connecting element and the second connecting element along a direction of connection is prevented and which allows a relative movement of the first connecting element and the second connecting element along the direction of connection in a release position, which makes a reliable releasable connection of two components with one another possible without weakening the relevant components unnecessarily due to channels it is suggested in accordance with the invention that the retaining part be movable from the retaining position into the release position by means of a driving magnetic field variable with time and acting on the connecting means from outside the connecting means. The present disclosure relates to the subject matter disclosed in International Application No. PCT/EP99/01064 (WO 99/43961) of Feb. 18, 1999, the entire specification of which is incorporated herein by reference.
Patent ES-2352745-T3 (ES)
Title: Cd86 de felino.
Inventor: CHOI IN-SOO
IPC: A61P31/04
Filed: 1999-04-30
Granted: 2011-02-22
Abstract: Un ácido nucléico que codifica un ligando de CD86 felino que tiene la SEC ID Nº 6 o un ligando de CD86 soluble que tiene la secuencia de aminoácidos de la SEC ID Nº 6 pero que carece de la región transmembrana o hidrófoba.
Patent ES-2306517-T3 (ES)
Inventor: OLSON LARS
IPC: A61K48/00
Filed: 1999-06-23
Granted: 2008-11-01
Abstract: According to the present invention, mutations in a gene associated with Parkinson's disease have been recognized for the first time ever. Thus, the invention relates to isolated human alcohol dehydrogenase 7 (ADH7) encoding nucleotides comprising one or more of the Parkinson related mutations M2-M7 as defined in Figure 4. Further, the present inventors have established that the previously published wild type sequence of ADH7 contains a mutation, herein denoted M1, and the invention further relates to the true wild type thereof. The invention also relates to nucleotides capable of specific hybridisation, under stringent conditions, to such nucleotides, as well as to peptides or proteins capable of binding any nucleotides according to the invention. In addition, the present invention is the first to recognize the connection between the previously published ADH7 sequence and Parkinson's disease. Thus, the invention relates to a pharmaceutical composition for treating and/or preventing Parkinson's disease caused by one or more of the mutations in the ADH7 gene defined above, which preparation comprises ADH7 or an analogue or functional fragment thereof in a pharmaceutically effective dose and a pharmaceutically acceptable carrier. The invention also encompasses the use of peptides, polypeptides or proteins capable of binding to the nucleotides comprising the sequences of the herein defined mutations and/or surrounding or adjacent sequences as medicaments as well as pharmaceutical compositions comprising the same.
Patent ES-2205867-T3 (ES)
Inventor: KLAVER RENATUS GERARDUS
IPC: G01B11/255
Filed: 1999-06-09
Granted: 2004-05-01
Abstract: Interferometer for measuring a phase difference between a reference beam (37) and an object beam (36') transformed by an optical element (10), comprising light source means (2), an optical device (3) and detection means (4) in a detection plane (34). The optical device (3) comprises a first light conductor (30) having a first output surface (31) that generates an object beam (36) having a spherical wave front and a second light conductor (32) having a second output surface (33) that generates a reference beam (37) having a spherical wave front, directed onto the detection plane (34), wherein the set-up of the first light conductor (30) and the optical element (10) is such that the transformed object beam (36') interferes with the reference beam (37) in the detection plane (34).
Patent ES-2265689-T3 (ES)
Inventor: QUINN CONRAD PADRAIG
IPC: C07K19/00
Filed: 1999-08-25
Granted: 2007-02-16
Abstract: A method of treating mucus hypersecretion, the causative factor in chronic obstructive pulmonary disease (COPD), asthma and other clinical conditions involving COPD, comprises administering a compound that inhibits exocytosis in mucus secreting cells or neurones that control or direct mucus secretion. Also described is a compound, for use in the treatment of hypersecretion of mucus, which inhibits mucus secretion by inhibiting mucus secreting cells, and/or inhibiting neurotransmitter release from neuronal cells controlling or directing mucus secretion.</PTEXT>
Patent ES-2188226-T3 (ES)
Title: Elemento de union para puentear el sitio de separacion de una junta dividida en una guarnicion de cable.
Inventor: MULLER THORSTEN
IPC: H02G15/013
Filed: 1999-07-01
Granted: 2003-06-16
Abstract: Junta para guarniciones de cables con un elemento de junta (D) alargado y transversalmente dividido, que presenta extremos (DE1, DE2) asociados a su sitio de separación y que está provisto, en dos lados longitudinales alejados uno de otro, de sendas concavidades longitudinales (V) que se extiende en la dirección longitudinal del elemento de junta (D) y que están abiertas hacia fuera, y con un elemento de unión (VE) que puentea el sitio de separación y que está constituido por una parte de fijación (FT) con dos elementos de tubo (RE) dispuestos a la distancia (A) uno de otro sobre un primer carril de unión (VS2) y una parte de cierre (VT) con espigas (Z) dispuestas a la misma distancia (A) sobre un segundo carril de unión (VS1), estando bloqueada la parte de fijación (FT) en el elemento de junta (D) por medio de la parte de cierre (VT) y correspondiendo la distancia (A) entre las espigas (Z) o los elementos de tubo (RE) a la distancia (AD) entre dos agujeros de alojamiento (AL) en los extremos (DE1, DE2) del elemento de junta (D) ensamblado en el sitio de separación, caracterizada porque el diámetro de los elementos de tubo (RE) es igual al diámetro de los agujeros de alojamiento, porque los extremos (DE1, DE2) del elemento de junta están alineados uno con otro por medio de la parte de fijación (FT) introducida con sus elementos de tubo (RE) en los agujeros de alojamiento (AL) y fijados sin holgura en una posición de ensamble a tope, . porque unos elementos de enclavamiento correspondientes (R, HS) están dispuestos en las espigas (Z) y en los elementos de tubo (RE) para producir un encastre mutuo, porque la pared dé limitación de la respectiva concavidad longitudinal (V) del elemento de junta (D) es de forma de arco en sección transversal, y porque tanto el primer carril de unión (VS1) como el segundo carril de unión (VS2) tienen en sección transversal una forma de arco vuelta hacia la respectiva concavidad longitudinal (V) y correspondiente a la forma de arco de la misma y están instalados con su forma de arco, estableciendo un cierre de forma, en la concavidad longitudinal correspondiente (V).
Patent ES-2183602-T3 (ES)
Title: Formulaciones microencapsuladas.
Inventor: WOLF HILMAR
IPC: A01N25/28
Filed: 1999-08-24
Granted: 2003-03-16
Abstract: Formulaciones microencapsuladas, constituidas por: A) por una fase dispersa en forma de partículas constituidas por un producto de reacción de - 2H-1,3,5-oxadiazin-2,4,6-(3H-5H)-trion- 3,5-bis-(6-isocianato-hex-1-il) de la fórmula en caso dado en mezcla con toluilen- diisocianato, con - etilendiamina-(1,2), dietilentriamina, trietilentetramina, bis-(3-aminopropil)-amina, bis-(2- metilaminoetil)-metilamina, 1,4-diamino-ciclohexano, 3- amino-1-metil-amino-propano, N-metil-bis-(3-aminopropil)- amina, 1,4-diamino-n-butano y 1,6-diamino-n-hexano, etanodiol, propanodiol-(1,2), propanodiol- (1,3), butanodiol-(1,4), pentanodiol- (1,5), hexanodiol-(1,6), glicerina y/o dietilenglicol, un producto activo fungicida del grupo de los amino-derivados, de los morfolino-derivados o de los azol- derivados y/o un producto activo insecticida del grupo de los ésteres del ácido fosfórico, de los piretroides o de los carbamatos y/o un producto activo herbicida del grupo de las acetanilidas así como en caso dado aditivos, presentando las partículas de la fase dispersa un tamaño medio de partículas comprendido entre 1 y 20 m y B) una fase acuosa, líquida.
Patent ES-2176026-T3 (ES)
Title: Aparato dispensador de un liquido volatil.
Inventor: SLADE BRIAN
IPC: B60H3/00
Filed: 1999-09-08
Granted: 2002-11-16
Abstract: Aparato dispensador de un líquido volátil que comprende un recipiente (2) que tiene un espacio interior substancialmente cerrado para el líquido y al menos un paso (88) para la comunicación con el exterior, caracterizado por el hecho de que dicho al menos un paso (88) es capilar y se prolonga desde una zona superior (8) del espacio interior adyacente a una pared o partición que se prolonga hacia arriba, de manera que el líquido es desplazado sobre dicha pared o partición para alcanzar dicho al menos un paso capilar (88) puede ser extraído a través de él para ser liberado del recipiente (2).
Patent ES-2234309-T3 (ES)
Inventor: RIGOULET FRANCK
IPC: A61K6/898
Filed: 1999-10-22
Granted: 2005-06-16
Abstract: A biological material for treating periodontal diseases and all related disorders, the biomaterial comprising biocompatible bioaragonite, added calcium carbonate and optionally a binding agent. The bioaragonite is mother-of-pearl in micronised form. It is obtained by inhibiting the most immunogenic part of the bioaragonite organic substance so as to maintain bioactive only the organic part associated with the mineral capable of having a positive effect.
Patent ES-2194525-T3 (ES)
Inventor: WELSER WOLFGANG
IPC: B23K26/08
Filed: 1999-11-15
Granted: 2003-11-16
Abstract: Previous methods for producing a profile section with varying wall thicknesses such as extrusion moulding, extrusion drawing or rolling are expensive and do not meet modern requirements in terms of dimensional accuracy. The objective of the invention is to provide a low-cost method for the production of profile sections with varying wall thicknesses, while guaranteeing dimensional accuracy. Strips are used as a starting material. Said strips are continuously fed into a welding installation and welded to each other on a longitudinal edge before being formed in a forming device. This enables profile sections with varying wall thicknesses to be produced at low cost and in a quick manner by using strips with the appropriate wall thicknesses. By simply changing the strips it is possible to produce different profile sections with low set-up times. The dimensional accuracy provided by the method is primarily directed towards the dimensional accuracy of strips that are used as a starting material. The inventive method is particularly suitable for strips that are made of aluminium, for instance, or steel with a wall thickness of up to 30 mm.
Patent ES-2281981-T3 (ES)
Inventor: WECHTER WILLIAM J
IPC: A61P29/00
Filed: 1999-09-03
Granted: 2007-10-01
Abstract: This invention relates to the use of enantiomerically pure R-NSAIDs for the treatment of inflammation. Preferably, the R-NSAID used is R-flurbiprofen and is administered in a dose of at least 5 milligrams per kilogram of body weight per day. The anti-inflammatory action of R-NSAIDs is due to their ability to interfere with the biosynthesis of COX-2 by inhibiting COX-2 mRNA synthesis, rather than by just blocking the action of the enzyme itself. In order to effect the inhibition of COX-2 mRNA synthesis, the R-NSAID must be present at relatively high doses. Because the R-NSAID is selective in its action, that is, it does not inhibit either COX-1 mRNA synthesis or the COX-1 enzyme itself, it can be administered in the required high doses because the tissue protective effects of prostaglandins made through the COX-1 pathway are not interfered with.
Patent ES-2334527-T3 (ES)
Title: Procedimiento y aparato para aumentar la sensibilidad de un receptor de satelite de posicionamiento global.
Inventor: SOLIMAN SAMIR S
IPC: G01S1/00
Filed: 1999-09-02
Granted: 2010-03-11
Abstract: Un procedimiento para mejorar la sensibilidad de un receptor GPS, que incluye las etapas de: a) recibir una señal GPS desde un satélite GPS; b) determinar si el receptor tiene una fuente para la sincronización a tiempo GPS; c) correlacionar la señal GPS recibida con una señal generada localmente codificada con un código particular asociado con un satélite particular durante cada uno de una pluralidad de periodos de código; d) si hay una fuente para la sincronización a tiempo GPS, entonces: i. determinar los límites de una pluralidad de periodos de código; ii. integrar los resultados de correlación sobre una pluralidad de periodos de código; y iii. determinar que se recibió una señal desde el satélite particular si el resultado de integración es mayor que un valor umbral; y e) si no hay ninguna fuente para la sincronización a tiempo GPS, entonces: i. realizar una transformada del dominio del tiempo al de la frecuencia sobre un resultado de la correlación y ii. analizar la salida del dominio de la frecuencia para determinar si se recibió una señal desde el satélite particular.
Patent ES-2296420-T3 (ES)
Title: Composicion azeotropica consistente en 1,1,1,3,3-pentafluoropropano y 1,1,1,-trifluoro-3-cloro-2-propeno, su procedimiento de separacion y purificacion, y procedimiento de produccion de 1,1,1,3,3-pentafluoropropano y de 1,1,1,-trifluoro-3-cloro-2-propeno.
Inventor: NAKADA T
IPC: C07C19/10
Filed: 1999-11-10
Granted: 2008-04-16
Abstract: Una composición azeotrópica consistente en 1, 1, 1, 3, 3-pentafluoropropano y 1, 1, 1-trifluoro-3-cloro-2-propeno.
Patent PL-1648933-T3 (PL)
Title: Long lasting insulin derivatives and methods thereof
Inventor: BRIDON DOMINIQUE P
IPC: C07K14/765
Filed: 2004-07-26
Abstract: The present invention relates to an insulin derivative comprising an insulin molecule and a reactive group for covalently bonding a blood component, wherein preferably the insulin molecule is human natural insulin molecule and the reactive group is coupled to an amino acid of the insulin molecule at a position selected from the positions Gly A1, Phe B1 and Lys B29.
Patent PL-1690075-T3 (PL)
Title: Field and storage chemical test method
Inventor: FORSYTHE JOHN M
IPC: G01N1/34
Filed: 2004-11-19
Abstract: A kit for transporting a sample from a first location to a second location comprises at least one container for holding the sample; an extraction solution disposed in the at least one container for dissolving a chemical of the sample; and an internal standard disposed in the at least one container for calibrating a quantitative measurement of the chemical.  A system for assaying an amount of a chemical on a tuber comprises a sampling means for collecting a tuber sample from the tuber; a kit comprising: at least one container for holding the tuber sample; an extraction solution for dissolving the chemical on the tuber sample; an internal standard for calibrating the chemical of the tuber; and a separation means for measuring an amount of the chemical in the extraction solution.
Patent PL-1824760-T3 (PL)
Title: Dispenser comprising electromagnetic locking with a magnet and reed switch
Inventor: ANDERSON JAMES
IPC: B65D83/16
Filed: 2005-12-07
Abstract: A material dispensing device (10) having a material container (12) and a dispensing section operable to control dispensing of a material from the material container (12) via the ejection section, wherein the material dispensing device (10) comprises electromagnetic locking means (28,30) comprising a first part (30) associated with the material container and a second part (28) associated with the dispensing section (14), wherein the electromagnetic locking means (28,30) is adapted to require the proximity of the first and second parts (28,30) to one another to adopt an unlocked configuration.
Patent PL-1932605-T3 (PL)
Title: Method and device for manufacturing wide strips made of copper or copper alloys
Inventor: ALBRECHT MICHAEL
IPC: B22D11/06
Filed: 2006-12-14
Abstract: Copper or copper alloys wide strips production involves pouring a molten liquid into a revolving wide strip mold (1). The surface of molten metal in the distribution container (9) is maintained at a constant level above the place, where the pour nozzle (14) is fixed in the distribution container in 75-90 mm range with the level of the bath surface (7) of the mold. The molten metal is guided by an ascending channel (11) from the distribution container to the pour nozzle. An independent claim is also included for a device for producing wide strips of copper or copper alloys.
Patent PL-1859438-T3 (PL)
Title: Method for providing an interactive voice service on a platform accessible to a client terminal, corresponding voice service, computer programme and server
Inventor: PAILLET ERIC
IPC: G10L15/22
Filed: 2006-02-27
Abstract: The invention concerns a method for providing an interactive voice service on a platform accessible to a client terminal, corresponding voice service, computer programme and application server. The invention concerns a method for providing at least one interactive voice service on at least one platform accessible to at least one client terminal. The invention is characterized in that upon access of one of the client terminals to one of the interactive voice service, the method includes a step of interpreting, via a phase engine (20) comprising at least one first software component, a description file (12) associated with the service and at least one second software component specific to the service. The phase engine (20) is reusable as such without any adaptation for different voice services. Only the description of the service differs.
Patent PL-1946583-T3 (PL)
Title: Associated paging indicator
Inventor: HUS OLIVIER J-M
IPC: H04W68/02
Filed: 2006-10-26
Abstract: A receiver for receiving wireless communication signals from a transmitter is arranged to operate in one of a plurality of states. The receiver is arranged to perform a state transition from the current state to another state among the plurality of states upon reception of a Paging Indicator Signal. The Paging Indicator Signal comprising an indication of the one of the plurality of states to which the state transition is to be performed.
Patent PL-1954924-T3 (PL)
Title: Variable valve timing apparatus
Inventor: INOUE YASUMICHI
IPC: F01L1/34
Filed: 2006-10-24
Abstract: In the case where an intake valve has its phase in a first region between a most retarded angle and CA( 1 ), the rotational speed of relative rotation between an output shaft of an electric motor and a sprocket is reduced at a reduction gear ratio R( 1 ) to change the phase of the intake valve. In the case where the intake valve has its phase in a second region between CA( 2 ) and a most advanced angle, the rotational speed of relative rotation is reduced at a reduction gear ratio R( 2 ) to change the phase of the intake valve. As long as the rotational direction of relative rotation is the same, the phase of the intake valve is changed in the same direction for both of the first region between the most retarded angle and CA( 1 ) and the second region between CA( 2 ) and the most advanced angle.