baber/WOPTO huggingface dataset:
Patent CA-2565996-A1 (CA)
Title: Combination of atypical antipsychotics and 5-ht1b receptor antagonists
Inventor: LIRAS SPIROS
IPC: A61K31/541
Filed: 2005-04-29
Abstract: The present invention relates to a pharmaceutical composition for treating, for example, a disorder or condition selected from the group consisting of hypertension, depression, generalized anxiety disorder, phobias, posttraumatic stress disorder, avoidant personality disorder, sexual dysfunction, eating disorders, obesity, chemical dependencies, cluster headache, migraine, pain, Alzheimer~s disease, obsessive-compulsive disorder, panic disorder, memory disorders, Parkinson~s diseases, endocrine disorders, cerebellar ataxia, gastrointestinal tract disorders, negative symptoms of schizophrenia, premenstrual syndrome, Fibromyalgia Syndrome, stress incontinence, Tourette syndrome, trichotillomania, kleptomania, male impotence, cancer, chronic paroxysmal hemicrania and headache in a mammal, preferably a human, comprising (i) an atypical antipsychotic or a pharmaceutically acceptable salt thereof, (ii) a 5-HT1B receptor antagonist or a pharmaceutically acceptable salt thereof, wherein the 5-HT1B receptor antagonist is selected from the group consisting of (A) a compound of the formula I as described in the specification and (B) a compound of the formula II as described in the specification, and optionally (iii) a pharmaceutically acceptable carrier.
Patent CA-2569436-A1 (CA)
Inventor: MENSA-WILMOT GRAHAM
IPC: E21B10/00
Filed: 2006-11-30
Abstract: A fixed cutter drill bit includes a plurality of gage pads, where certain of the gage pads have an active cutting region adjacent to the end of the gage pad adjacent to the bit face, and a passive region at the end of the gage pad adjacent to the pin-end of the bit. The active regions include forward-facing cutter elements. Other gage pads include an active region on the end adjacent to the pin-end, and a passive region on the gage pad end adjacent to the bit face. The passive and active regions have lengths within the range of 40 to 60 percent of the total axial length of the gage pads. A passive gage pad is positioned on the bit between the gage pads having both active and passive regions.
Patent CA-2569465-A1 (CA)
Title: Method for purifying erythropoietin
Inventor: HESSE JAN-OLE
IPC: C07K14/505
Filed: 2005-06-07
Abstract: The invention relates to a method for producing recombined erythropoietin having a particularly high degree of purity (>=98%). The method consists of at least 5 chromatographic purification steps, i.e. at least two anion exchange chromatographs, at least one hydrophobic interaction chromatography, at least one affinity chromatography and at least one hydroxyapatite chromatography. In preferred embodiments, the method does not require any exclusion chromatography and any reversed-phase chromatography. The invention relates to, in particular, a method wherein the following chromatographic purification steps have the following order; i) a first anion exchange chromatography, ii) an affinity chromatography, which relates, preferably, to a dye affinity chromatography, iii) a hydrophobic interaction chromatography, iv) an hydroxyapatite chromatography and v) a second anion exchange chromatography.
Patent CA-2572033-A1 (CA)
Inventor: LI JIANGNAN
IPC: B26D7/01
Filed: 2006-12-22
Abstract: The present invention is to provide a tile cutter in simple configuration having a locking device of dual locking functions. The tile cutter comprises a support frame, a cutting device mounted on the support frame, at least one rail disposed on the support frame, a worktable assembly slidably installed in or on a first rail of the at least one rail and a water tray. The first rail has a longitudinal axis. The worktable assembly comprises a first worktable and a second worktable. One of the support frame and the water tray is mounted or placed on the other one of the support frame and the water tray. A locking device is mounted between the first worktable and the second worktable. The locking device comprises a first locking portion and a second locking portion.
Patent CA-2572415-A1 (CA)
Inventor: CUTTS PETER GEORGE
IPC: B05B1/18
Filed: 2005-06-30
Abstract: The present invention relates to a shower fitting. In particular, but not exclusively, the invention relates to a wall outlet and a shower elbow (100) that allows passage of water and also provides a means for supporting articles (101).
Patent CA-2577490-A1 (CA)
Title: Prodrugs containing alkyldisulfide linker groups
Inventor: SATYAM APPARAO
IPC: A61K47/48
Filed: 2005-08-26
Abstract: The invention provides the compounds of formula (I) or pharmaceutically acceptable salts thereof. The invention also provides pharmaceutical compositions comprising one or more compounds of formula (I) or intermediates thereof and one more of pharmaceutically acceptable carriers, vehicles or diluents. The invention further provides methods of preparation and methods of use of prodrugs including NO-releasing prodrugs, double prodrugs and mutual prodrugs comprising the compounds of formula (I).
Patent CA-2577677-A1 (CA)
Inventor: TERMIN ANDREAS P
IPC: C07D471/00
Filed: 2005-08-19
Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
Patent CA-2578657-A1 (CA)
Title: Method, system and apparatuses for short message group-delivering
Inventor: CHEN DE
IPC: H04B7/26
Filed: 2005-09-05
Abstract: A method for short message group-delivering, the method includes: setting on a network a group of short message group-delivering including a group ID and IDs of destination user terminals; receiving by the network a request for short message group-delivering including the group ID and the contents of a short message; determining the group according to the group ID, obtaining the IDs of the destination user terminals, and sending the contents of the short message to the determined destination user terminals one by one. By the method, a source user terminal need not repeatedly send short messages with same contents to each destination user terminal during short message group-delivering, thus the delivery time and radio resources are saved.
Patent CA-2582585-A1 (CA)
Title: Cartridge separator for immiscible liquids
Inventor: BENACHENHOU AMINE
IPC: B01D17/025
Filed: 2007-03-26
Abstract: A separator of the present invention provides a means for separating a immiscible dispersion of at least one oil from water. The separator adapted for use with a flow generator, includes a housing, a coalescing cartridge within the housing, the cartridge retains a coalescing media and defines at least one cavity or passage, permitting flow of the dispersion into and out of the passage; and a flow regulator comprising a constriction and the regulator displaceable between an open and a closed position and permitting liquid flow out of the passage when in the open position. The separator allows a greater throughput of coalesced oil/water dispersions through the separator due to removal during of coalesced oil and clarified oil during regular operational mode and the backwash mode, and further permits the use of the incoming or non-coalesced dispersion for backwash mode
Patent CA-2584091-A1 (CA)
Inventor: MEINDERS ERWIN R
IPC: G11B7/26
Filed: 2005-10-12
Abstract: The present invention relates to a master substrate (10) for optical recording comprising a recording layer (12) and a substrate layer (14), the recording layer comprises a growth dominated phase-change material, the chemical properties with respect to chemical agents of which may be altered due to a phase change induced by projecting light on the recording layer. For tracking purposes, the substrate layer comprises pre-grooves (16). The present invention further relates to a method of manufacturing a stamper for replicating a high-density relief structure.
Patent CA-2584142-A1 (CA)
Title: Improved viral purification methods
Inventor: COFFEY MATTHEW C
IPC: C12N7/02
Filed: 2005-10-21
Abstract: The present invention is directed to an improved method of purifying virus, particularly reovirus. Infectious virus can be extracted from a cell culture with a detergent to produce high titers of virus, and the virus can then be purified by simple steps such as filtration and column chromatography. Viruses and compositions comprising the viruses prepared according to the present invention are also provided.
Patent CA-2584434-A1 (CA)
Inventor: YOO STEVE
IPC: B42F21/08
Filed: 2007-04-05
Abstract: File dividers having slidable tabs for systematic and efficient management of files are provided. A track is attached to a file divider such that the track runs substantially parallel to a file divider edge. A tab has a terminal end that wraps around a portion of the track to be capable of sliding along the track. In another embodiment, a slit running substantially parallel to a file divider edge is formed on an extended leaf, so that terminal portions of a tab can be inserted into the slit to be able to slide along the slit.  In still another embodiment, a guiding track substantially parallel to a file divider edge slideably interlocks with a mating member of a tab. Lastly, a tab can have a pair of retention lips to hold a support bar or a track in order to be capable of sliding along the support bar or the track.
Patent CA-2584619-A1 (CA)
Title: Amide compound
Inventor: MATSUMOTO TAKAHIRO
IPC: G01N33/50
Filed: 2005-11-17
Abstract: An FAAH inhibitor; and a preventive/therapeutic agent for cerebrovascular disorders and a preventive/therapeutic agent for sleep disorders which each contains the inhibitor. The FAAH inhibitor is a compound represented by the formula (I0): (wherein Z represents oxygen or sulfur; R1 represents optionally substituted aryl or an optionally substituted heterocyclic group; R1a represents hydrogen, an optionally substituted hydrocarbon group, hydroxy, etc.; R2 represents optionally substituted piperidine-1,4-diyl or optionally substituted piperazine-1,4-diyl; R3 represents an optionally substituted group formed by removing two hydrogen atoms from a 5-membered aromatic heterocycle having 1-3 heteroatoms selected among nitrogen, oxygen, and sulfur, or represents -CO-, etc.; and R4 represents an optionally substituted hydrocarbon group or optionally substituted heterocyclic group) or a salt of the compound.
Patent CA-2586283-A1 (CA)
Inventor: KILDSGAARD JENS
IPC: A61K39/35
Filed: 2005-11-08
Abstract: The present invention relates to a method of preventive treatment of allergy to an allergen in a subject comprising administering an allergy vaccine containing the allergen as active substance to a mucosal surface of the subject, a) wherein the subject to be treated is sensitised so as to exhibit an IgE response specific to the allergen, b) wherein the subject to be treated is free of clinical symptoms of the allergy associated with the allergen, and c) wherein the preventive treatment is aimed at preventing or reducing subsequent clinical symptoms of the allergy associated with the allergen.
Patent CA-2587250-A1 (CA)
Inventor: LUECKERL BARBARA
IPC: A61K9/20
Filed: 2005-12-20
Abstract: A solid pharmaceutical composition comprising a poorly water soluble drug,a polymer which is solid at room temperature, and a disintegrant in an amount of less than 10% by weight, wherein the amounts by weight are based on the total weight of the composition.
Patent CA-2589837-A1 (CA)
Inventor: HOLMES JON A
IPC: H04N5/91
Filed: 2007-05-23
Abstract: Une méthode de recherche dimages numériques comprend lentrée de données qui identifient un sujet dune image dans une caméra, lacquisition dune image avec la caméra et le stockage de limage et des données entrées, comme des métadonnées, dans un fichier image une fois limage acquise. La méthode peut être mise en uvre en utilisant un numériseur, une caméra numérique et un processeur de données. Le numériseur obtient les données didentification et les transmet à la caméra. La caméra obtient des images numériques et intègre les données dans des fichiers dimage numérique qui codent les images numériques. Les données didentification ont un format différent de tous les formats traitables par la caméra numérique. Le processeur de données convertit le format des données didentification à lun de la pluralité des formats traitables par la caméra numérique et charge les renseignements convertis dans la caméra numérique sous forme de métadonnées.
Patent CA-2591067-A1 (CA)
Inventor: THOMAS GARETH
IPC: C21D6/00
Filed: 2005-11-29
Abstract: A carbon steel alloy that exhibits the combined properties of high strength, ductility, and corrosion resistance is one whose microstructure contains ferrite regions combined with martensite-austenite regions, with carbide precipitates dispersed in the ferrite regions but without carbide precipitates are any of the interfaces between different phases. The microstructure thus contains of four distinct phases: ( 1 ) martensite laths separated by ( 2 ) thin films of retained austenite, plus ( 3 ) ferrite regions containing ( 4 ) carbide precipitates. In certain embodiments, the microstructure further contains carbide-free ferrite regions.
Patent CA-2592111-A1 (CA)
Inventor: THOMAS MATTHEW E
IPC: G01M3/20
Filed: 2005-11-18
Abstract: The invention may be used for detecting fluid leaks in a fluid containment element having a primary element (64, 72) enclosed in a secondary element (62, 78). A fluid container (30) may have a reservoir (12) with an upstanding test cylinder (14) with a selected fluid volume. A device may be disposed in the test cylinder (14) to determine the level of a test fluid (40). There may be a closure (18) for a top opening (20) and the closure (18) may have a hole (24).  A nonexpandable conduit (26) may connected at a first end to the hole (24) and at a second end to a pressurized gas supply (32). The fluid container (30) may have an outlet port (38) therein and a first end of an outlet nonexpandable conduit (26) may be connected to the outlet port (38). A block valve (36) may be disposed in the outlet nonexpandable conduit (26). The fluid container (30) may be pressurized by the introduction of a gas from the pressurized gas supply (32).
Patent CA-2592613-A1 (CA)
Title: Packages
Inventor: BRAY ANDREW JONATHAN
IPC: B31B50/64
Filed: 2006-01-25
Abstract: A package comprises first and second packs (Pl, P2) each capable of containing items. Each pack has a base, and a first face (Fl, Fl') bound by a first edge (El, El') and a second edge (E2, E2') which co-operate with the base to contain items in the packs. Means (JL) connect the first and second packs (Pl, P2), the means comprising at least first and second straps (Sl, S2). In a first position of the packs the first faces (Fl, Fl') of each pack face each other with the first edges (El, El') of the first and second packs adjacent each other and the second edges (El, E2') of the first and second packs adjacent each other. The first and second straps (Sl, S2) extend across the first faces (Fl, Fl') of the packs, the first strap (Sl) is hinged relative to the first pack at the first edge (El) of the first pack and hinged relative to the second pack at the second edge (E2') of the second pack, and the second strap (S2) is hinged relative to the second pack (P2) at the first edge (El') of the second pack and hinged relative to the first pack at the second edge of the first pack. When connected together by the straps (Sl, S2), the first and second packs (Pl, P2) are moveable, one relative to the other between at least the first position, a second position in which the second pack (P2) is rotated relative to the first pack (Pl) about the first edge (El) and a third position in which the second pack (P2) is rotated relative to the first pack (Pl) about the second edge (E2').
Patent CA-2594662-A1 (CA)
Title: Mitotic kinesin inhibitors
Inventor: COX CHRISTOPHER D
IPC: C07D207/50
Filed: 2006-02-06
Abstract: The present invention relates to tricyclic pyrazoles that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Patent CA-2594738-A1 (CA)
Inventor: HAMILTON DAVID S
IPC: G06Q30/02
Filed: 2007-07-04
Abstract: The present invention is a packaged kit to assist a person in planning and executing a social event, especially a groom's pre-wedding party. The kit comprises a box or envelope containing preferably everything the host will need to put on a successful party. For example, the kit will contain a complete set of instructions for the host, plus optionally a scheduling form and a checklist. The kit will also contain invitations for each invitee with directions to the event, and envelopes with adhesive-backed labels for printing from a mailing list on a computerized printer. Also, the kit will contain coupons and/or gift certificates from manufacturers and/or retailers for each invitee, as well as, optionally, for the guest. The kit may also contain thank--you notes for the guest with pre-printed address labels to the invitees, for convenience. The kit may be hard copy, computer disk or Internet enabled, for example.
Patent CA-2600758-A1 (CA)
Inventor: BIRNBOIM CHAIM H
IPC: C12N9/50
Filed: 2006-03-14
Abstract: An aqueous composition comprising a denaturing agent, a chelator, a buffering agent and a protease for the extraction of nucleic acid from a sample of bodily fluid, such as saliva, such that the extracted nucleic acid is stable for at least fourteen days at room temperature and can be directly utilised in an amplification reaction without further processing. In particular, said composition comprises SDS, Cyclohexanediamine tetraacetate, Tris-HCl and proteinase K. A method and kit for the amplification of DNA directly from a bodily fluid, comprising said composition, is further provided.
Patent CA-2600962-A1 (CA)
Inventor: LIVET CAHTERINE
IPC: G01R31/08
Filed: 2006-03-09
Abstract: A mesh network includes a plurality of mesh points (MPs), a central database (DB) and a central controller (CC). The MPs are configured to broadcast quality of service (QoS) information over a wireless medium. Each MP may request QoS information directly from at least one other one of the MPs. The MPs store QoS information in the central DB and are configured to query the central DB QoS information associated with any of the MPs. Thus, QoS  information is shared throughout the mesh network, and QoS policies are defined and updated where an MP may co-exist with another MP, an MP may co-exist with systems external to the mesh network, and an MP may co-exist with mesh access points (MAPs).
Patent CA-2601575-A1 (CA)
Title: Spirocyclic thrombin receptor antagonists
Inventor: CHELLIAH MARIAPPAN V
IPC: A61P9/00
Filed: 2006-03-29
Abstract: Heterocyclic-substituted tricyclics of the formula or a pharmaceutically acceptable salt or solvate of said compound, isomer or racemic mixture wherein represents an optional double bond, the dotted line is optionally a bond or no bond, resulting in a double bond or a single bond, as permitted by the valency requirement and wherein An, En, Mn, Un, Gn, Jn, Kn, R9, R10, R11, R32, R33, B  and Het are herein defined and the remaining substituents are as defined in the specification, are disclosed, as well as pharmaceutical compositions containing them and a method of treating diseases associated with thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure, and cancer by administering said compounds. Combination therapy with other cardiovascular agents is also claimed.
Patent CA-2601970-A1 (CA)
Title: Secure device authentication
Inventor: IWAMURA RYUICHI
IPC: H04L9/00
Filed: 2006-02-15
Abstract: A method for authenticating a client device into a network consistent with certain embodiments involves at a server device, generating a multi-digit random secret number; displaying the random secret number on a server display coupled to the server device; positioning the client device in close enough physical proximity to the server device to permit observation of the displayed random secret number; at the client device, sequentially entering each digit of the random secret number by actuation of a switch coupled to the client device a number of times equivalent to each digit of the random secret number;  and upon correct entry of the random secret number at the client device, completing an authentication and key exchange process using the random secret number in an encryption and decryption process carried out at the server device and the client device. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
Patent CA-2605329-A1 (CA)
Title: Method for determination of cholesterol in high-density lipoprotein
Inventor: FUJINAKA MAYUMI
IPC: C12Q1/26
Filed: 2006-04-27
Abstract: The present invention provides a method, a reagent and a kit for the simple and accurate measurement of HDL  cholesterol. The method for the measurement of cholesterol in high-density lipoprotein in a sample comprises reacting the sample with i) cholesterol esterase and cholesterol oxidase or ii) cholesterol esterase, oxidized coenzyme and cholesterol dehydrogenase in an aqueous medium comprising a specific nitrogen-containing surfactant having the structure of amine or ammonium salt and a polyanion, and measuring the formed hydrogen peroxide or reduced coenzyme.
Patent CA-2609475-A1 (CA)
Inventor: ESTACIO EDGARDO Y
IPC: F02F11/00
Filed: 2007-11-05
Abstract: A gasket (200) includes a metal substrate (202) that has a first opening (204) and a second opening (216) formed therein. A first sealing bead (208) substantially surrounds the first opening (204). A second sealing bead (220) substantially surrounds the second opening (216). A leak conduit (230) is formed in the metal substrate (202) in an area (228) between the first sealing bead (208) and the second sealing bead (220), such that a leak-flow (316) of a first fluid from the second opening (216) past the second sealing bead (220) is routed away from the first sealing bead (208).
Patent CA-2609832-A1 (CA)
Inventor: HENRIKSSON MAGNUS
IPC: D21C9/06
Filed: 2006-05-31
Abstract: The invention relates to a washing arrangement (200) for washing and dewatering of cellulose pulp, comprising a rotatable drum (202) with a plurality of outer compartments (204) on the drum for the pulp to be washed, which compartments are defined by axial compartment walls (204b) distributed along the circumference of the drum, a stationary cylindrical casing (208) that encloses the drum, whereby an annular space (210) is defined between the casing and the drum and where the annular space by means of longitudinal seals (212) in the axial direction of the drum is divided in zones (F, Tl, T2, U) for forming, washing and discharge of the pulp. At least two of the longitudinal seals are arranged such that they, when the drum rotates, meet compartment walls at shifted points in time with respect to each other.  Preferably all of these longitudinal seals are arranged along the circumference of the drum at different positions with respect to respective opposite axial compartment walls.