Patent SG-11201900773R-A (SG)
Title: Methods for optical micropatterning of hydrogels and uses thereof
Inventor: PARKER KEVIN
IPC: C08J5/18
Filed: 2017-08-04
Abstract: Riboflavinremoval and rehydration Rehydrated UV laser micropatterned gelatin FIG. Casting of gelatin elatin solution UV laser housing COC- carrier Riboflavin treatment and UV laser etching (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 08 February 2018 (08.02.2018) W I P0 I P C T olimion °nolo olioloio mom liflovoimIE (10) International Publication Number WO 2018/027105 Al (51) International Patent Classification: BOIL 3/00 (2006.01) B32B 27/32 (2006.01) B29C 71/04 (2006.01) B41M 5/44 (2006.01) B32B 27/08 (2006.01) C08J 5/18 (2006.01) B32B 27/24 (2006.01) (21) International Application Number: PCT/US2017/045442 (22) International Filing Date: 04 August 2017 (04.08.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/371,385 05 August 2016 (05.08.2016) US (71) Applicant: PRESIDENT AND FELLOWS OF HAR- VARD COLLEGE [US/US]; 17 Quincy Street, Cam- bridge, MA 02138 (US). (72) Inventors: PARKER, Kevin, Kit; 29 Oxford Street, Cam- bridge, MA 02138 (US). NAWROTH, Janna, C.; 22 Clive Street, #3, Boston, MA 02130 (US). SCUDDER, Lisa; 68 Bartlett Avenue, Belmont, MA 02478 (US). (74) Agent: ZACHARAKIS, Maria, Laccotripe et al.; Mc- carter & English, LLP, 265 Franklin Street, Boston, MA 02110 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, (54) Title: METHODS FOR OPTICAL MICROPATTERNING OF HYDROGELS AND USES THEREOF 1-1 1-1 N (57) : The present invention provides methods for optically micropatteming hydrogels, which may be used for, e.g., regener- O ative medicine, synthetic or cultured foods, and in devices suitable for use in high throughput drug screening assays. C [Continued on next page] WO 2018/027105 Al D III TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(H)) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: — with international search report (Art. 21(3))