baber/WOPTO huggingface dataset:
Patent AU-2022201076-A1 (AU)
Title: Bispecific antibodies against plasma kallikrein and factor XII
Inventor: COMEAU STEPHEN R
IPC: C12N9/64
Filed: 2022-02-17
Abstract: BISPECIFIC ANTIBODIES AGAINST PLASMA KALLIKREIN AND 
FACTOR XII 
ABSTRACT 
Described herein are bispecific antibodies that bind to plasma kallikrein (pKal) and Factor XII 
and methods of producing and using such bi-specific antibodies for treating diseases or disorders 
associated with the contact system, e.g., hereditary angioedema or thrombosis. One aspect of the 
present disclosure is a bispecific antibody, comprising: a first polypeptide that comprises a light 
chain of a first antibody, the light chain comprising a light chain variable region (VL) and a light 
chain constant region (CL) (e.g., a kappa light chain or a lambda light chain); and a second 
polypeptide that comprises a heavy chain of the first antibody, the heavy chain comprising a 
heavy chain variable region (VH) and a heavy chain constant region (CH).
Patent AU-2022201730-A1 (AU)
Title: A water heating system and an intake and exhaust system thereof
Inventor: HIREMATH RAVINDRA
IPC: F24H9/00
Filed: 2022-03-11
Abstract: An intake and exhaust system for supplying air to and venting a water heating system, 
comprising: 
5 (a) an intake duct which, in use, is in fluid communication with water 
heaters and configured to intake air from the atmosphere via an intake end of the duct 
and supply it to the heaters; and 
(b) an exhaust duct which, in use, is in fluid communication with the 
heaters and configured to vent exhaust from the heaters to the atmosphere via an 
10 exhaust end of the exhaust duct; 
wherein at least the intake and exhaust ends of the respective ducts form part of 
a single intake and exhaust unit, the unit being configured such that, in use, it extends 
through a roof or wall of a building structure serviced by the hot water system and into 
the atmosphere and both intakes air for supply to the heaters and vents exhaust 
15 therefrom.
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Patent AU-2022207454-A1 (AU)
Title: Camptothecine antibody-drug conjugates and methods of use thereof
Inventor: Chuprakov Stepan
IPC: A61K47/68
Filed: 2022-01-13
Abstract: The present disclosure provides antibody-drug conjugate (ADC) structures where the antibody-drug conjugate includes a camptothecine or a camptothecine derivative linked to a polypeptide (e.g., an antibody) through a linker. In addition, the disclosure also encompasses compounds and methods for production of such conjugates, as well as methods of using the conjugates.
Patent AU-2022208206-A1 (AU)
Title: Solvated crystalline polynuclear metal complex solvated with a mixture of non-polar and polar solvents, such solvated crystalline polynuclear metal complex including a guest compound analyte and its use in a method for determining molecular structure of the guest compound analyte
Inventor: KUEHN CLEMENS
IPC: C07F3/00
Filed: 2022-01-14
Abstract: The present invention is directed to solvated crystalline polynuclear metal complexeswhich solvation is with a polar solvent or a mixture of polar and non-polar solvent. These polar solvated crystalline metal complexes of the present invention can absorb an analyte guest compound, including an polar analyte guest compound, to form a crystal structure analysis sample. The molecular structure of the analyte guest compound can be determined by X-ray crystallography using the crystal structure analysis sample obtained with such solvated crystalline polynuclear metal complexes.
Patent AU-2022208387-A1 (AU)
Title: Compounds and use thereof for treatment of neurodegenerative, degenerative and metabolic disorders
Inventor: BANNISTER THOMAS
IPC: A61K31/428
Filed: 2022-01-14
Abstract: Provided are,
Patent AU-2022225981-A1 (AU)
Title: Novel method and agent for treating, diagnosing and detecting diabetes and complications
Inventor: KOJIMA HIDETO
IPC: A61K45/06
Filed: 2022-02-25
Abstract: The present disclosure provides a therapy for diabetes that targets abnormal stem cells by using an HDAC inhibitor combined with stem cell migration. In one embodiment, the present disclosure provides a therapy for diabetes and/or diabetes-related diseases, disorders and/or symptoms, said therapy targeting abnormal stem cells, by using an HDAC inhibitor combined with stem cell migration. In one embodiment, the present disclosure provides a therapy for diabetes and/or diabetes-related diseases, disorders and/or symptoms, said therapy targeting abnormal stem cells, by using an HDAC inhibitor combined with stem cell migration in a subject having abnormal stem cells detected therein.
Patent AU-2022252296-A1 (AU)
Title: Methods and compositions for the ablation of nerves
Inventor: JARRETT TIM
IPC: A61K9/00
Filed: 2022-03-30
Abstract: Methods, devices and materials are for a pharmaceutically acceptable implant system. The implant system may comprise a neuromodulating agent, solid particulate hydrogel particle, a carrier medium in a different physical phase, and in situ formation of a singular depot for sustained release of said agent.
Patent AU-2022256174-A1 (AU)
Title: Microbiota restoration therapy (MRT) compositions and methods of manufacture
Inventor: JONES LEE A
IPC: A61K35/74
Filed: 2022-10-20
Abstract: Microbiota restoration therapy (MRT) compositions (e.g., oral MRT 
compositions) and methods for manufacturing MRT compositions are disclosed. An 
example method for manufacturing an MRT composition may include collecting a 
5 stool sample, purifying the stool sample to form a purified sample, stabilizing the 
purified sample to form a stabilized sample, converting the stabilized sample to a 
solid, adding one or more additives and/or excipients to the solid to form a treatment 
composition, and encapsulating the treatment composition.
Patent AU-2022259757-A1 (AU)
Title: Integration of multiple electronic records
Inventor: NAFTZGER DAVID
IPC: G06Q50/14
Filed: 2022-10-26
Abstract: A computer-implemented method for integrating multiple electronic travel- related 
records, the method comprising: obtaining travel information; loading a corporate 
profile; loading a traveler profile; instructing that a search be carried out for a 
flight; and processing at least one booking based on a predetermined customer 
rule.
Patent AU-2022270648-A1 (AU)
Title: Large-conductance potassium channel modulators, compositions thereof, methods of manufacturing thereof, and methods of use thereof
Inventor: PERGOLIZZI JOSEPH V
IPC: A61K31/53
Filed: 2022-05-04
Abstract: Disclosed herein are methods of treating a disease or condition modulated by large-conductance potassium channels, the methods including administering, to a patient in need thereof, an effective amount of a large-conductance potassium channel modulating compound. Exemplary disease or conditions that may be treated include, without limitations, protection against ischemia and hypoxia at multiple points throughout the body, as well as respiration stimulation in the presence of such conditions (both local and systemic). Also described herein are pharmaceutical compositions for use in the methods of treatment of a disease or condition modulated by large-conductance potassium channels, and methods of preparing such pharmaceutical compositions.
Patent AU-2022271458-A1 (AU)
Title: Play Apparatus
Inventor: MANN MILES
IPC: A63B71/02
Filed: 2022-11-17
Abstract: A trampoline comprising a bounce area, wherein the bounce area comprises a plurality of portions, the 
plurality of portions comprising at least a first portion disposed in a first plane, a second portion disposed 
in a second plane, the second plane being different from the first plane, and a third portion disposed in a 
third plane, wherein the third plane is different from the first plane and/or different from the second plane.
Patent AU-2022277812-A1 (AU)
Title: Process for degrading a plastic product comprising at least one polyester
Inventor: MARTY ALAIN
IPC: C08J11/10
Filed: 2022-05-20
Abstract: The present invention relates to a process for degrading plastic, wherein said plastic products are selected from plastic and/or textiles comprising polyester comprising at least a terephthalic acid monomer. The process of the invention particularly comprises a step of enzymatic depolymerization implemented in acidic conditions at a pH between 3 and 6.
Patent AU-2022288702-A1 (AU)
Title: Determining pathogenic rfc1 expansions from sequencing data
Inventor: CHEN SAI
IPC: G16B20/20
Filed: 2022-06-10
Abstract: Disclosed herein include systems, devices, and methods for determining repeat expansion status (e.g., pathogenic, carrier, and benign) of a locus of a gene of interest (e.g., at, or at about, chr4:39348424 of hg38 for RFC1). After aligning sequence reads to a sequence graph, the number of occurrences of repeat sequences satisfying predetermined criteria and the frequency of a pathogenic repeat sequence can be determined, which are in turn used to determine a repeat expansion status.
Patent AU-2022292640-A1 (AU)
Title: Selective targeting of host cd70+ alloreactive cells to prolong allogeneic car t cell persistence
Inventor: LAURON ELVIN J
IPC: A61K39/00
Filed: 2022-06-15
Abstract: Provided herein are CD70-binding proteins comprising a CD70-binding domain and a transmembrane domain, engineered immune cells comprising the CD70-binding proteins, and methods of making and using the same. Also provided herein are engineered immune cells e.g. CAR (chimeric antigen receptor) T cells for administration to patients to treat cancer (e.g., solid tumors and hematologic tumors) and other unwanted conditions. The cells are engineered to functionally express a first antigen binding molecule e.g. a CD70 CAR and a second antigen binding molecule e.g. a second CAR that binds a target molecule characteristic of the cancer or other disease or unwanted condition. The cells may be further engineered to reduce the functional expression level of one or more of TRAC, CD52 and CD70. Also provided are methods of making and using the engineered cells, compositions and kits comprising them, and methods of treating by administering them.
Patent AU-2022310170-A1 (AU)
Title: Method of screening antioxidants
Inventor: BATCHVAROVA NIKOLETA
IPC: G01N21/64
Filed: 2022-07-14
Abstract: Methods of screening types and amounts of antioxidants, determining effectiveness of the antioxidants, preparing compositions including effective amounts of the antioxidants (and uses thereof), and reducing the formation of clogged pores and acne are provided. Methods include the formation of test samples in a solvent system (optionally with one or more bacterial metabolites) including one or more antioxidants in amounts to be evaluated for effectiveness against control samples without antioxidants. The samples are exposed to an oxidation-inducing element (such as UVA rays) and the amount of oxidation byproduct is evaluated. Based on the effectiveness of the antioxidant(s) in the amount(s) tested, formulations can be prepared to include the one or more antioxidants in the amount(s) effective to reduce oxidation of the oxidizable component, preventing and reducing the formation of the oxidation byproduct. The formulations can be used, for example, to reduce the formation of clogged pores and acne.
Patent AU-2022377211-A1 (AU)
Title: Pvc-based multilayer surface covering with pvoh barrier
Inventor: SICHE ALEXANDRE
IPC: C08J7/04
Filed: 2022-10-28
Abstract: A (decorative) surface covering, for use in finishing work in constructions or vehicle interiors, is proposed. The surface covering comprises: o a PVC-based layer, the PVC-based layer optionally comprising inorganic filler (such as, e.g., calcium carbonate, magnesium carbonate, ground limestone or chalk, gypsum, etc.), and o a barrier layer directly adjacent the PVC-based layer, the barrier layer comprising polyvinyl alcohol and a polyisocyanate derivative obtained through reaction of a polyisocyanate with hydroxyl groups of the polyvinyl alcohol, the polyisocyanate derivative bonding the barrier layer to the PVC-based layer. A method for preparing such a surface covering is also disclosed.
Patent AU-2023202143-A1 (AU)
Title: Fire fighting training system with steam/smoke generation
Inventor: BLACKBURN JOHN JOSEPH
IPC: G09B19/00
Filed: 2023-04-06
Abstract: A firefighting training system including a display device configured to display an 
actual or simulated fire and a sensor configured to detect an actual, simulated or virtual 
extinguishant that is directed at the display device. The system further includes a smoke or 
steam generation system configured to provide an output and a controller operatively coupled 
to the display device, the sensor and the generation system. The controller is configured to 
control the display of the actual or simulated fire and the output based at least in part upon an 
output of the sensor.
Patent AU-2023203981-A1 (AU)
Title: Adjustable insole for a footwear article
Inventor: PLESSAS DIMITRIS
IPC: A43B17/02
Filed: 2023-06-23
Abstract: Various embodiments are directed to an adjustable insole for a footwear article. In various 
embodiments, the adjustable insole comprises an insole body comprising a heel bottom cavity 
defined by a cavity opening provided along an insole body bottom surface; and a removeable heel 
bottom insert configured to be disposed within the heel bottom cavity such that a first insert portion 
is disposed within the heel bottom cavity and a second insert portion defines a lowermost surface 
of the adjustable insole, the removeable heel bottom insert having a selectively adjustable 
configuration relative to the insole body that is defined by an arrangement of the removeable heel 
bottom insert within the heel bottom cavity in one of a nominal position and a rotated position 
defined relative to the nominal position by a rotation of the removeable heel bottom insert through 
an angle of rotation of at least approximately 90 degrees.
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Patent AU-2023204193-A1 (AU)
Title: Nozzle for cleaner
Inventor: KO MOOHYUN
IPC: A47L11/20
Filed: 2023-06-30
Abstract: A nozzle for a cleaner comprises a nozzle body including a 
suction passage in which air flows, a water tank detachably 
mounted in the nozzle body, and a rotation cleaning part 
rotatably provided at a lower side of the nozzle body to receive 
water of the water tank and to clean a floor. The water tank 
comprise an outlet through which water is discharged, a valve 
configured to open and close the outlet, an air hole configured 
to introduce outside air into the water tank, and an operation 
part movably provided on the water tank to open and close the air 
hole.
Patent AU-2023208111-A1 (AU)
Title: Dynamic execution of parameterized applications for the processing of keyed network data streams
Inventor: RAVID ODED
IPC: G06F40/00
Filed: 2023-07-25
Abstract: A method is described for processing keyed data items that are each associated with a 
value of a key, the keyed data items being from a plurality of distinct data streams, the 
processing including collecting the keyed data items, determining, based on contents of at least 
one of the keyed data items, satisfaction of one or more specified conditions for execution of one 
or more actions and causing execution of at least one of the one or more actions responsive to the 
determining.
Patent AU-2023254895-A1 (AU)
Title: Photovoltaic cell, method for manufacturing same, and photovoltaic module
Inventor: LI RUIFENG
IPC: H01L31/04
Filed: 2023-10-24
Abstract: A photovoltaic cell is provided, which includes a substrate; a first passivation layer 
and a first anti-reflection layer disposed on a front surface of the substrate; and a second 
passivation layer, a PPW layer and at least one silicon nitride layer SiN, disposed on a 
rear surface of the substrate; wherein 1<u/v<4, and a refractive index and thickness of 
which is in a range of 1.9 to 2.5 and 50 nm to 100 nm; wherein the second passivation 
layer includes at least one aluminum oxide layer AlxOy, wherein 0.8<y/x<1.6, and a 
refractive index and thickness of which is respectively in a range of 1.4 to 1.6 and 4 nm 
to 20 nm; wherein the PPW layer includes at least one silicon oxynitride layer SirOsN, 
wherein r>s>t, and a refractive index and thickness of which is respectively in a range of 
1.5 to 1.8 and 1 nm to 30 nm.  
28
Patent AU-2023263552-A1 (AU)
Title: Distribution and playback of media content
Inventor: Eliezer GARTEN
IPC: H04N21/2343
Filed: 2023-11-10
Abstract: Techniques and systems are provided for processing media data. For example, methods, 
apparatuses, and computer-readable media are described that can include receiving a multicast 
stream of media content, and dividing the multicast stream of media content into data fragments.  
In some cases, the multicast stream of media content can be transcoded from a first media format 
to a second media format. The data fragments can be transmitted, over one or more Transmission 
Control Protocol (TCP) channels using a web socket protocol, to a browser of the computing 
device for playback.
Patent AU-2023286027-A1 (AU)
Title: A control device for an electronic aerosol provision system
Inventor: MOLONEY PATRICK
IPC: A24F47/00
Filed: 2023-12-28
Abstract: A control device for an electronic aerosol provision system is configured to receive a 
replaceable component to form an electronic aerosol provision system. The control device is 
further configured to receive an identifier from a replaceable component received by the 
control device; and to modify one or more characteristics (such as resistance to draw, RTD) of 
an airflow path through the electronic aerosol provision system dependent upon the received 
identifier.  
Figure 1
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Figure 1
Patent AU-2024200221-A1 (AU)
Title: Editing a database during preview of a virtual web page
Inventor: BLUMENFELD UVAL
IPC: G06F3/048
Filed: 2024-01-12
Abstract: EDITING A DATABASE DURING PREVIEW OF A VIRTUAL WEB PAGE 
ABSTRACT 
Disclosed embodiments relate to updating a back-end database containing data sets that 
populate a plurality of web pages of a website. Operations include receiving via a user interface, 
a plurality of data elements; storing groups of at least one data element in a database; generating 
a plurality of virtual web pages, wherein each virtual web page is a preview of a corresponding 
actual web page before the corresponding actual web page goes live; displaying each group of at 
least one data element in a separate one of the plurality of virtual web pages; displaying an 
editing tool to permit a user to edit a virtual web page from the plurality of virtual web pages; 
translating the edits to the virtual web page into updates for the database; storing the updates in 
the database; and enabling a display on the corresponding actual web page with the updates.
Patent WO-2012083392-A1 (WO)
Title: Метод и устройство для прямого преобразования радиационной энергии в электрическую
Inventor: GARLANOV DIMO TODOROV
IPC: G21H1/00
Filed: 2011-10-31
Abstract: Метод и устройство находит применение в энергетике, в частности ядерной, и в электропромышленности. Реализованная батарея - аккумулятор представляет объемную систему из линейно упорядоченных плоских электрических емкостей, названой преобразователь (1). В их междуэлектродном пространстве расположен сменяемый, наноразмерный, кластерный, с композитным строением порошкообразный материал (4), обладающий изоляционным и ферромагнитным свойствами и выполняющий функцию дискретного изолятора (5). Таким образом оформленный, преобразователь (1) поставлен в защитный кожух (16), имеющий боковые расположенные напротив друг друга отверстия (17), подвергается комбинированному, управляемому и проникающему в его объем воздействию радиационного лучения α-, β- и γ- лучей и магнитному полю (7).
Patent WO-2008064440-A1 (WO)
Title: Vaccin contre des streptococcus beta-hémolytiques du groupe a et processus respectif permettant de l'obtenir
Inventor: GUGLIELMI LUIZA GUILHERME
IPC: A61K38/16
Filed: 2007-07-19
Abstract: L'invention concerne un vaccin contre des streptococcus beta-hémolytiques du groupe A et un processus respectif permettant de l'obtenir qui prévoit la production d'une protéine recombinante clonée à partir du gène emm5. Ce vaccin contient une séquence d'oligonucléotides correspondant à 52 et/ou 87 résidus d'acides aminés apte à protéger, isolés après l'identification moléculaire séquentielle des épitopes en provenance de la région carboxy-terminale de la protéine M, dont ils différent de 01 résidu d'acides aminés, identifiés par les anticorps et lymphocytes T d'êtres humains en santé et de patients porteurs de rhumatisme articulaire aigu, apte à générer une réponse protectrice par des anticorps en fonction des lymphocytes T ; la prévention du développement de la maladie auto-immune par l'épitope sélectionné a été évaluée in vitro avec les lymphocytes T d'un tissu cardiaque de patients avec des lésions découlant d'un rhumatisme articulaire aigu.
Patent WO-2012100313-A1 (WO)
Inventor: SCHWARZ MARCOS GUILHERME
IPC: F04B35/04
Filed: 2012-01-25
Abstract: La présente invention concerne un système de commande destiné à un compresseur hermétique pour réfrigération, comprenant un compresseur alternatif et une commande électronique (2) destinée au compresseur alternatif (3), la commande électronique (2) pouvant être conçue pour déterminer, après commande de l'arrêt du compresseur alternatif, si la vitesse de rotation de l'axe rotatif (10) est inférieure à un niveau de vitesse prédéfini, puis à appliquer un couple de freinage provoquant la décélération de l'axe rotatif (10) avant l'exécution de la rotation suivante de l'axe rotatif (10) lorsque la vitesse de rotation détectée est inférieure audit niveau de vitesse.
Patent WO-2017049369-A1 (WO)
Title: Sistema e método de monitoramento e fiscalização de tráfego e registro de infrações de trânsito em trecho ou segmento de via
Inventor: DA SILVA ADRIEL BILHARVA
IPC: G06T7/20
Filed: 2015-09-21
Abstract: A presente invenção se refere a um sistema e método de monitoramento a fiscalização de tráfego e registro de ínfrações de trânsito em trecho ou segmento de via, em que dito sistema compreende, em uma área de monitoramento (100), pelo menos duas unidades de processamento local (UPL A , UPL B ,... UPL n ), pelo menos duas células de monítoramerito (CEL A , CEL B ,... CEL n ) resultantes da subdivisão da área de monitoramento (100) e atribuídas, cada uma, individualmente e inequivocamente, a uma unidade de processamento local (UPL A , UPL B , UPL n ) correspondente, pelo menos uma região de sobreposição (SP AB , SP BC ,...   SP (n),(n+1) ) entre as células de moritoramento (CEL A , CEL B ,... CEL n ), pelo menos uma unidade de processamento central (UPC), pelo menos um canal de comunicação entre unidades de processamento (UPL A , UPL B ,... UPL n ) e a unidade de processamento central (UPG) e pelo menos um programa de computador específico para gerenciamento e comunicação entre os componentes compreendidos pelo sistema e execução do método correspondente.