baber/WOPTO huggingface dataset:
Patent CA-2490268-A1 (CA)
Title: Protein glycosylation modification in pichia pastoris
Inventor: WOUTER VERVECKEN
IPC: C12N9/24
Filed: 2003-06-25
Abstract: The present invention provides genetically engineered strains of methylotrophic yeast including Pichia and especially Pichia pastoris capable of producing proteins with reduced or modified glycosylation. Methods of producing glycoproteins with reduced and/or modified glycosylation using suc h genetically engineered strains of Pichia are also provided. Vectors, which comprise coding sequences for .alpha.-1,2-mannosidase I, glucosidase II, GlcNAc-tranferase I and mannosidase II or comprising OCH1 disrupting sequenc e, for transforming methylotrophic yeasts are contemplated by the present invention. Kit for providing the contemplated vectors are also included in this invention.
Patent CA-2495600-A1 (CA)
Inventor: BALLAI PHILIP N
IPC: G06F9/44
Filed: 2003-08-18
Abstract: Described is a system and method for automatically updating a firmware program. During an initialization process of a portable card (e.g., a wireless radio card), a first version of the firmware program is determined. The first version is a version which is currently stored in a non-volatile memory of the card that is connected with a computing device. The first version is compared with a second version of the firmware program. The first version is automatically updated with the second version in the non-volatile memory if the second version is a subsequent verison of the firmware program. After the firmware is updated, the card is activated using the second version.
Patent CA-2496037-A1 (CA)
Title: Methods and configurations for catalyst regeneration
Inventor: CHU HUMBERT HSI-SHAN
IPC: C01B32/50
Filed: 2002-08-21
Abstract: A catalyst regenerator (100) has a first section (110) and a second section (120) and is operated such that carbon from a carbon-contaminated catalyst (140) is converted to carbon monoxide in the first section (110) and that carbon monoxide is converted to carbon dioxide in the second section (120). The residence time of the oxygen-containing gas in the first and second sections (110, 120) is regulated in preferred configurations by the shape (e.g., diameter) of the first and second sections (110, 120).
Patent CA-2496705-A1 (CA)
Inventor: BROOKER BRIAN EDWARD
IPC: A23G9/20
Filed: 2003-08-12
Abstract: Selon l'invention, des particules de graisse alimentaire sont précristallisées et mélangées avec une phase aqueuse précurseur de crème glacée en présence d'au moins un émulsifiant afin de former une dispersion. Les particules précristallisées de graisse alimentaire contiennent chacune différents cristaux. La dispersion obtenue est gazéifiée et congelée afin de former une crème glacée. La précristallisation se fait de préférence par cryogénie.
Patent CA-2497487-A1 (CA)
Title: Noise attenuation apparatus for borehole telemetry
Inventor: MONMONT FRANCK BRUNO JEAN
IPC: E21B47/18
Filed: 2003-08-19
Abstract: A surface mud pipeline system is described with a mechanical acoustic filter (1245) tuned to a predetermined frequency band so as to attenuate pump noise (132) within this band. The filter can be combined with a Venturi constricti on to provide enhanced attenuation and is used to improve signal transmission o f a mud pulse telemetry system (113-2).
Patent CA-2498807-A1 (CA)
Title: Dispositif d'analyse de composes a analyser et utilisation dudit dispositif
Inventor: CHEN FEI
IPC: G01N33/543
Filed: 2003-09-11
Abstract: L'invention concerne un dispositif analytique composé de matériau(x) poreux permettant la migration d'un liquide. Ce dispositif comprend, dans le sens de migration, une première zone sur laquelle peut être appliqué un échantillon suspecté de contenir une substance à analyser, une deuxième zone incorporant une molécule non immobilisée capable de se lier spécifiquement à cette substance à analyser, ladite molécule étant pourvue d'un marqueur détectable, une troisième zone capable de réduire la vitesse de migration de l'échantillon et de la molécule non immobilisée ainsi qu'une quatrième zone incorporant dans au moins une partie de cette zone à l'état immobilisé le même type de substance que la substance à analyser ou une substance analogue à cette dernière capable de se lier spécifiquement à la molécule non immobilisée.
Patent CA-2500346-A1 (CA)
Inventor: SIMMONS JOHN W
IPC: B01D53/22
Filed: 2003-10-27
Abstract: La présente invention concerne une membrane perméable aux gaz de manière sélective qui comprend une combinaison supérieure de perméabilité et sélectivité. La composition de la membrane comprend un copolyimide de Type 1 mélangé uniformément à un copolyimide de Type 2, ces polymères ayant la structure chimique décrite plus spécifiquement dans l'invention. L'invention a également pour objet un procédé pour utiliser la membrane faite du mélange de copolyimides pour séparer des composantes de mélanges gazeux.
Patent CA-2502237-A1 (CA)
Inventor: TEGELER TONY J
IPC: G01N30/72
Filed: 2003-08-21
Abstract: A fluid treatment device (10) is disclosed for mixing first (14) and second fluids. The first fluid (14) may be a treatment liquid that is contained in a container (12) and that is used to change a property, such as the pH, densit y or ionic strength, of the second fluid. In some illustrative embodiments, th e fluid treatment device (10) is used to create an effluent by adding a buffer material and/or a matrix material to an analyte for subsequent MALDI MS analysis of the effluent. A mixing space (54) is defined in a container (12) between ends of first and second conduits. In some embodiments, a junction member (26) couples together the ends of the first and second conduits. The junction member (26) has at least one opening that provides fluid communication between an interior region of the container (12) and the mixin g space (54).
Patent CA-2503247-A1 (CA)
Title: Screening methods for identification of efficient pre-trans-splicing molecules
Inventor: MITCHELL LLOYD G
IPC: C12Q1/68
Filed: 2003-10-23
Abstract: The present invention provides methods and compositions for rapid high capacity functional screening to identify optimal pre-trans-splicing molecul es (PTMs). The compositions of the invention include PTM expression libraries capable of encoding candidate PTMs designed to interact with a target precursor messenger RNA molecule (target pre-mRNA) and mediate a trans- splicing reaction resulting in the generation of a novel chimeric RNA molecu le (chimeric RNA). The candidate PTMs of the invention encode a portion of a first reporter molecule and may encode one or more other reporter molecules, which can be used to select for cells expressing optimal PTMs (efficient and specific). The compositions of the invention also include cells that express a target pre-mRNA encoding the remaining portion of the first reporter molecul e. The screening methods of the invention encompass (i) contacting a PTM expression library with cells expressing a target pre-mRNA under conditions in which a trans-splicing reaction will occur in the presence of an optimal PTM (expressed by the library vector) resulting in the formation of a chimeric repaired RNA molecule capable of encoding at least one reporter molecule; (i i) selecting for cells expressing the repaired reporter molecule wherein expression of the reporter molecule indicates the presence of an optimal PTM in the selected cell; and (iii) identifying the optimal PTM expressed in the selected cell(s). The additional reporter molecule(s) can be used to assess both specific and non-specific trans-splicing, as well direct PTM expression .
Patent CA-2503555-A1 (CA)
Title: Lamp holder with ground fault circuit interrupter receptacle
Inventor: PORTER A JAMES
IPC: H02H3/00
Filed: 2005-04-06
Abstract: A lamp holder has provisions for mounting a lamp socket and a ground fault circuit interrupter (QFCI) receptacle. The lamp holder includes an opening sized to accommodate the GFCI and at least one opening sized to accommodate the lamp socket. The lamp holder can be mounted to a standard outlet box and can have a provision to accommodate a lamp socket having a pull-chain switch.
Patent CA-2506746-A1 (CA)
Title: Method of drug loading in liposomes by gradient
Inventor: HU NING
IPC: A61K9/127
Filed: 2003-11-26
Abstract: A method for encapsulation of pharmaceutical agents (e.g., antineoplastic agents) in liposomes is provided, having preferably a high drug:lipid ratio. Liposomes can be made by a process that loads the drug by an active mechanis m using a transmembrane pH gradient. Using this technique, trapping efficienci es approach 100%. Drug:lipid ratios employed are higher than for older traditional liposome preparations, and the release rate of the drug from the liposomes is reduced. After loading, residual acid is quenched with a quenching agent that is base permeable at low temperatures. The residual aciditiy is thus reduced and chemical stability (e.g. against hydrolysis) is enhanced. The stability of both the liposome and the pharmaceutical agent is thus maintained, prior to administration. The pH gradient is, however, prese nt when the liposome is administered in vivo because the quenching agent rapidl y exits the liposome.
Patent CA-2512968-A1 (CA)
Title: Breaking reentry circuits by cooling cardiac tissue
Inventor: MOWER MORTON M
IPC: A61N1/365
Filed: 2004-01-12
Abstract: Systems and methods to inhibit the conduction of certain spurious electrical impulses in the heart. Inhibition of spurious electrical impulses in the heart is accomplished by cooling (110) one or more targeted portions of the heart.  Optionally, inhibition of spurious electrical impulses may be accomplished by cooling of cardiac tissue in combination with pacing of the heart.
Patent CA-2513297-A1 (CA)
Title: Resin composition
Inventor: ERENS IVO
IPC: C08F232/00
Filed: 2004-01-15
Abstract: The present invention refers to a resin composition comprising an ester compound and a polymer, wherein the ester compound and the polymer are obtainable by reacting a diene, a dienophile and a carboxylic acid. The invention also refers to adhesive compositions comprising the resin composition.
Patent CA-2514878-A1 (CA)
Title: Drug formulation and delivery using crystalline methylated cyclodextrins
Inventor: CHANG RONG-KUN
IPC: A61K31/70
Filed: 2004-02-02
Abstract: The present invention is directed to pharmaceutical compositions containing crystalline methylated, which enhance the solubility of the pharmaceutically active agent or agents of the formulation.
Patent CA-2516534-A1 (CA)
Inventor: MYTTING DAVID
IPC: A45B3/00
Filed: 2005-09-28
Abstract: "In the invention entitled multi-purpose Hiking Tool, Patent Application #2,347,201, construction of some of the tools were slow and cumbersome. With theses modifications the walking stick, stool, brush saw and brush axe will fit together smoother and easier."
Patent CA-2519236-A1 (CA)
Title: Corpus clustering, confidence refinement, and ranking for geographic text search and information retrieval
Inventor: FRANK JOHN R
IPC: G06F17/30
Filed: 2004-03-18
Abstract: A computer-implemented method for processing a plurality of toponyms, the method involving: in a large corpus, identifying geo-textual correlations among readings of the toponyms within the plurality of toponyms; and for each toponym selected from the plurality of toponyms, using the identified geo-textual correlations to generate a value for a confidence that the selected toponym refers to a corresponding geographic location. Also a method of generating information useful for ranking a document that includes a plurality of toponyms for which there is a corresponding plurality of (toponym,place) pairs, there being associated with each (toponym,place) pair of said plurality of (toponym,place) pairs a corresponding value for a confidence that the toponym of that (toponym,place) pair refers to the place of that (toponym,place) pair. This further method includes, for a selected (toponym,place) pair of the plurality of (toponym,place) pairs, (1) determining if another toponym is present within the document that has an associated place that is geographically related to the place of the selected (toponym, place) pair; and (2) if a toponym is identified within the document that has an associated place that is geographically related to the place of the selected (toponym, place) pair, boosting the value of the confidence for the selected (toponym,place) pair.
Patent CA-2519400-A1 (CA)
Title: Operating device for a computer
Inventor: SNIJDERS CHRISTIAAN JOHANNES
IPC: G06F3/0354
Filed: 2004-01-08
Abstract: Operating device such as a mouse for operating a computer or the like. This device consists of a flat bearing surface on which a bulbous part has been arranged. This bulbous part consists of three (curved) surfaces, a surface for the palm of the hand for supporting the metacarpus/carpus, a central surface for supporting the proximal phalanges of the fingers and a distal surface for supporting the medial and distal phalanges. According to the present invention, the distal surface is made at an angle of approximately 75~ with respect to the bearing surface. As a result of this angle there is optimum support for the fingers over the entire contour and it is possible to prevent RSI-like phenomena by preventing lifting movements of the fingers, which in the long term give rise to RSI-like phenomena.
Patent CA-2522776-A1 (CA)
Title: Hydrogenation of polytrimethylene ether glycol
Inventor: DIFFENDALL GEORGE FRANCIS
IPC: C08G65/322
Filed: 2004-05-05
Abstract: A process comprising contacting PO3G having color with hydrogen in the presence of a hydrogenation catalyst, wherein the PO3G, after hydrogenation, has an APHA color of less than about 50.
Patent CA-2523787-A1 (CA)
Inventor: ZHANG HAO
IPC: A61K9/70
Filed: 2004-05-10
Abstract: A water-dissolvable drug delivery device designed so as to reliably maintain a drug or active agent within a defined region against a mucosal surface. The drug delivery device comprises a water-dissolvable backing layer, an adhesive layer adjacent to at least a portion of the backing layer, and an active layer that is circumscribed by the backing layer and adhesive layer. The backing layer may optionally include a water-dissolvable hydrophilic region and a non-hydrophilic region at least partially encapsulated within the hydrophilic region that inhibits migration of water, drugs, or other active agents through the backing layer. The adhesive layer may be water-activated or it may have a peelable cover layer that, when removed, exposes the adhesive material. The active layer may comprise any drug or other active agent, either alone or in combination with (i) an enhancer that increases the ability of the drug or other active agent to diffuse through a mucosal membrane and/or (ii) a matrix material such as an alginate to hold the active layer together.
Patent CA-2525084-A1 (CA)
Title: Processing of titanium-aluminum-vanadium alloys and products made thereby
Inventor: HICKMAN RANDALL W
IPC: C22F1/18
Filed: 2004-05-05
Abstract: A method of forming an article from an .alpha.-.beta. titanium including, in weight percentages, from about 2.9 to about 5.0 aluminum, from about 2.0 to about 3.0 vanadium, from about 0.4 to about 2.0 iron, from about 0.2 to about 0.3 oxygen, from about 0.005 to about 0.3 carbon, from about 0.001 to about 0.02 nitrogen, and less than about 0.5 of other elements. The method comprises cold working the .alpha.-.beta. titanium alloy.
Patent CA-2526586-A1 (CA)
Title: The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
Inventor: TAMM MICHAEL
IPC: A61P9/00
Filed: 2004-09-03
Abstract: According to a first aspect the invention relates to the use of fumaric acid derivatives selected from the group consisting of dialkyl fumarates, monoalkyl hydrogen fumarates, fumaric acid monoalkyl ester salts, fumaric acid monoamides, monoamido fumaric acid salts, fumaric acid diamides, monoalkyl monoamido fumarates, carbocyclic and oxacarbocyclic oligomers of these compounds and mixtures thereof for preparing a drug for the treatment or prevention of cardiac insufficiency, in particular left ventricular insufficiency, myocardial infarction and angina pectoris. According to a second aspect the invention relates to the use of fumaric acid derivatives, selected from the group consisting of dialkyl fumarates, monoalkyl hydrogen fumarates, fumaric acid monoaklyl ester salts, fumaric acid monoamido fumaric acid salts, fumaric acid diamides, monoalkyl monoamido fumarates, carbocyclic and oxacarbocyclic oligomers of these compounds and mixtures thereof for preparing a drug for the treatment of asthma and chronic obstructive pulmonary diseases, especially asthma caused by allergies, infections, analgesics, job conditions or physical effort, mixed forms of asthma, or asthma cardiale.
Patent CA-2526910-A1 (CA)
Inventor: AGRAWAL AVNEESH
IPC: H04B1/12
Filed: 2004-05-07
Abstract: Techniques are provided to support soft handoff in a frequency hopping OFDMA  system. Each sector concurrently supports "non-handoff" users and "soft-handoff" users. A non-handoff user communicates with only one sector, and a soft-handoff user communicates with multiple sectors simultaneously. Non-handoff users are assigned traffic channels by their sole sectors, and soft-handoff users are assigned traffic channels by their "serving" sectors. For each sector, the traffic channels assigned to the non-handoff users are orthogonal to one another and may or may not be orthogonal to the traffic channels assigned to the soft-handoff users. Each sector processes its received signal and recovers the data transmissions from the non-handoff users of that sector. Each sector then estimates the interference due to the non-handoff users and cancels the interference from the received signal. Each sector further processes its interference-canceled signal to recover the data transmissions from the soft-handoff users.
Patent CA-2532179-A1 (CA)
Inventor: LENZINI MARTIN JOHN
IPC: B25B11/00
Filed: 2004-04-23
Abstract: A vacuum hold-down device comprising a base member (1) and a separate workpiece support (8) which co-operate to define a vacuum chamber. The device further comprises a venturi (15) having an inlet port (7) for connection to a source of pressurized fluid, an outlet (9) for fluid from the venturi, and a fluid connection (19, 5) from a low pressure region of the venturi (15) to the inside of the vacuum chamber, for providing a partial vacuum therein. The partial vacuum will hold the base member (1) and the workpiece support (8) together to maintain a peripheral seal therebetween. The workpiece support (8) is provided with securing means (16) for securing a workpiece (10) thereon.  The invention also provides a vacuum hold-down system comprising the base member (1) and a plurality of interchangeable workpiece supports (8).
Patent CA-2532701-A1 (CA)
Inventor: HEDSTROM KRISTEN K
IPC: A47L15/42
Filed: 2006-01-12
Abstract: A dishwasher includes a first washing chamber and a second washing chamber capable of performing a washing operation separately and/or concurrently. Each washing chamber includes a wash pump, a drain pump and a heating unit that are operatively connected to a controller. When initiating a washing fluid in one washing chamber, the controller determines if the other washing chamber is active. If the other washing chamber is active, the heating unit for the one washing chamber is operated at a low power level. However, if the other washing chamber is inactive, the one washing chamber is operated at a high power level to rapidly heat the washing fluid and thus shorten the duration of the washing operation.
Patent CA-2535661-A1 (CA)
Title: Structural knee bolster
Inventor: ROYCHOUDHURY RAJ S
IPC: B62D1/11
Filed: 2004-09-01
Abstract: A bolster for assembly to an instrument panel assembly of an automotive vehicle is provided. The vehicle has a steering column with a steering column axis and at least two energy absorbing brackets located laterally to either side of the steering column axis. The bolster comprises a unitary structure having a generally forward wall and a generally aft wall. The forward wall has a forward wall, forward surface. The forward wall, forward surface includes first and second bolster transfer surfaces for transferring forces from the bolster to the energy absorbing brackets. The bolster further comprises a plurality of generally laterally extending rib structures. The rib structures extend from adjacent the first bolster transfer surface to adjacent the second bolster transfer surface. The plurality of generally laterally extending ribs structures have sufficient strength to inhibit bending of the bolster about a vertical plane when struck by a driver's knees at a point or points that are not directly aft of the bolster transfer surfaces, when the force is equal to or less than an amount specified by a test standard.
Patent CA-2537110-A1 (CA)
Title: Convertisseur d'energie des vagues (wec) a freinage magnetique
Inventor: STEWART DAVID B
IPC: H02K35/02
Filed: 2005-03-15
Abstract: L'invention concerne un système de freinage magnétique qui permet d'inhiber un mouvement excessif entre une structure flottante et une colonne destinées à être positionnées dans un plan d'eau, la structure flottante et la colonne se déplaçant l'une par rapport à l'autre en fonction des vagues présentes dans le plan d'eau. Ce système de freinage comprend un ensemble à aimants permanents (PMA) monté sur la structure flottante ou sur la colonne, et relié à une de ces dernières ; ainsi qu'un jeu de bobines (ou un plateau conducteur) monté sur l'autre élément, la structure flottante ou la colonne, et relié à une de ces dernières. Ledit système de freinage est monté de façon que le mouvement entre la structure flottante et la colonne soit entravé lorsque le déplacement de la structure flottante par rapport à la colonne dépasse une plage de fonctionnement prédéterminée.
Patent CA-2538516-A1 (CA)
Title: Geographical indexing system and method
Inventor: ABBISS ROGER OWEN
IPC: G09B29/00
Filed: 2006-03-03
Abstract: A geographical indexing system and method for use in association with a plurality of search results and a user-selected location. A  user-selected location is obtained by providing a user with a graphical geographical map and receiving a user-selected location on the graphical geographical map.  Geographically indexed search results are obtained by indexing a plurality of search results by geographical proximity to the user-selected location, and displaying those results to the user. A set of targeted search results are then determined from the indexed search results and a user request for information is obtained. The user request for information is then sent to a set of targeted search result contacts associated with the targeted search results and the responses are received and aggregated and then displayed, stored or forwarded to the user.
Patent CA-2539298-A1 (CA)
Title: Method for efficient, nonsynchronous lng production
Inventor: WRIGHT STEPHEN
IPC: F02C7/268
Filed: 2004-09-20
Abstract: A drive system for a refrigeration compressor such as is used in a natural gas liquefaction plant, allowing the desired compressor speed and maximum turbine efficiency to be maintained throughout varying ambient temperature conditions.  A gas turbine is used with an electric starter motor with drive-through capability located on a common drive shaft between the turbine and the compressor. A variable frequency drive (VFD) is connected between the electrical power grid and the electric motor for smooth startups, but also to allow excess turbine mechanical power to be converted to electrical power by the motor operating as a generator, and delivered to the grid at the grid frequency. Pulse width modulation technology may be used to reduce harmonic distortion in the VFD's output. The starter motor also functions as a helper motor when the turbine output is insufficient to drive the compressor at the rotational speed needed to meet throughput requirements.