baber/WOPTO huggingface dataset:
Patent GE-P20084340-B (GE)
Title: Pharmaceutical compositions comprising fentanyl for intranasal delivery
Inventor: CASTILE JONATHAN DAVID
IPC: A61K9/00
Filed: 2004-01-12
Abstract: This invention provides a composition for the intranasal delivery of fentanyl or a pharmaceutically acceptable salt thereof to a patient. A composition comprises an aqueous solution of (i) fentanyl or a pharmaceutically acceptable salt thereof and (ii) pectin, provided that when the composition comprises pectin it is substantially free of divalent metal ions.
Patent GE-P20115249-B (GE)
Title: Transdermal delivery system on the basis of form stable hydrogels
Inventor: NADIRASHVILI NUGZAR
IPC: A61K9/10
Filed: 2008-04-10
Abstract: Transdermal delivery system contains diclo¬fenac sodium, dimethyl sulfide, diethylamine¬hydrochloride, polysaccharide hydro gel and water.
Patent GE-P20115337-B (GE)
Title: Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
Inventor: SCHULTZ-FADEMRECHT CARSTEN
IPC: C07D401/10
Filed: 2008-01-08
Abstract: The present invention relates to compounds of formula (I)    (I) and pharmaceutically acceptable salts, stere¬o¬iso¬mers or tautomers thereof, which are inhibitors of poly(ADP-ribose) polymerase (PARP) and are useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ische¬mic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardi¬ovascular dise¬ases, diabetes, neurodegenerative diseases, retro¬viral infection, retinal damage or skin senescence and UV-induced skin damage, and preparation of medicinal means used as chemo- and/or radiosensitizers for cancer treatment.
Patent GE-P201706703-B (GE)
Title: Boronate ester compounds and pharmaceutical compositions thereof
Inventor: ELLIOTT ERIC L
IPC: C07K5/06
Filed: 2009-06-16
Abstract: Compounds of formula (II), pharmaceutical compositions on basis thereof and usage thereat cancer treatment. Table: 	31
Patent GE-P20207084-B (GE)
Title: Five stroke rotary combustion engine, with volumetric expansion
Inventor: CHILASHVILI GIORGI
IPC: F02B57/00
Filed: 2018-08-27
Abstract: An engine comprises housing-stator 2 having inner cylindrical surface and a cover 36, with liquid cooling system channels 32 located therein, two – in¬ner 9 and outer 6 rotors are installed rotable in the case; furthermore, it is equipped with combustion chamber 1, working chamber, an atmospheric air in¬¬¬let channel 96 and exhaust gas removal channel 95 into the atmosphere, a channel 58 connecting combustion chamber with working chamber, a cha¬n¬nel 57 for purging residual combustion gases from combustion chamber into working chamber and output shaft 24; at that, outer rotor is located in the center, and the inner one is eccentric, in the case, the number of pistons is two and each therefrom are made plate piston shaped, one wherefom is desig¬ned for compression-expansion 65, connected to the external rotor and simultaneously movable connec¬tion 94 is connected to internal rotor, and another is inlet-outlet 28, mounted onto output shaft, passed in inner rotor movable connection 78 and fits capable of sliding to outer rotor inner surface; at that, said working chamber is arranged to move changeable in volume in different zones, and is formed in the space between outer rotor inner cylindrical surface, part of inner rotor outer cylindrical surface and the pistons; furthermore, the engine is additionally equ¬ip¬ped with floating ring 4 having channels located between outer rotor and stator housing inner cylin¬drical surface, between stator housing inner cylin¬drical surface and floating ring, there is elastic sea¬ling component 3 made of thermally expanding gra¬p¬hite, and honeycomb sealing element 5 is placed between floating ring and outer rotor; at that, at le¬ast one path for gas distribution is formed bet¬ween honeycomb sealing component and outer rotor ou¬ter surface, the engine is equipped with self-braking wedge mechanisms 21 and 46 containing detecting force sensors having signal amplifier 38, wedge mechanism drive 48, assessment and control unit providing constant compaction of outer and inner rotors co-adjacenting radial surfaces, as well.
Patent CA-1263612-C (CA)
Title: Fiber bed separator
Inventor: KOCATAS BABUR MEHMET
IPC: B01D39/02
Filed: 1985-06-28
Granted: 1989-12-05
Abstract: 17-21(6219)A FIBER BED SEPARATOR ABSTRACT OF THE INVENTION A fiber bed separator formed of a bed of staple fibers is provided. A discontinuity is created within the bed of fibers at a selected location to improve the drainage of liquids from the fiber bed.
Patent CA-1265420-C (CA)
Title: Process for making internally hardened tubes
Inventor: BEAR WILLIAM H
IPC: C21D9/08
Filed: 1985-07-16
Granted: 1990-02-06
Abstract: "PROCESS FOR MAKING INTERNALLY HARDENED TUBES" ABSTRACT OF THE DISCLOSURE The present invention relates to a process for hardening the interior surface of a long, thin-walled, small inside diameter, tubular member, such as a tube which would be used to form a downhole pump barrel. More particularly, it relates to a process involving progressive heating with an internally positioned, electro-magnetic induction coil, followed by immediate quenching with a quench ring assembly, to develop a martensitic case on the inner surface of the tube. The invention further extends to the apparatus utilized in conducting the process, and to the product tube itself.
Patent CA-1314042-C (CA)
Title: Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents
Inventor: BOMMER JERRY C
IPC: A61P43/00
Filed: 1986-04-30
Granted: 1993-03-02
Abstract: ABSTRACT This invention relates to new fluorescent mono, di- or polyamide of an aminomonocarboxylic acid and a tetrapyrrole containing at least three carboxy groups of the structure:                         wherein Z is the amino acid residue and X is the tetrapyrrole residue and "n" is an integer from 1 to 4 inclusive.
Patent CA-1288097-C (CA)
Inventor: FRANCIS JOHN E
IPC: C07D487/04
Filed: 1986-09-26
Granted: 1991-08-27
Abstract: 4-15519/1+2/CGC 1151 2-SUBSTITUTED-e-FUSED[1,2,4]TRIAZOLO[1,5-c]PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF            Abstract of the Disclosure Compounds of the formulae Ia, Ib and Ic   (Ia)              (Ib)         (Ic) wherein X  is O, S, NH or NR; R  is alkyl, alkenyl, alkynyl, cycloalkyl, aromatic-ring-alkyl all of which may be optionally interrupted by a herero atom; OH; an aromatic ring; or the group -C(=NH)-NH2; R1 is optionally substituted and selected from a carboxylic aromatic and a heterocyclic group which heterocyclic group is aromatic, partially saturated or fully saturated, the optional substituent of R2 being halogen, alkyl, haloalkyl, OH, alkoxy, hydroxyalkyl, amino, mono- or di-alkylamino, carbalkoxy, carbamoyl and alkylcarbamoyl; R2 is H, alkyl, hydroxy-C2-C4-alkyl, alkenyl, arylalkyl, or arylalkenyl; A  is a bivalent bridging group containing chain atoms selected from C, O, N and S thus forming together with the two adjacent carbon atoms to which the chain is attached a mono- or bicyclic carbocyclic or heterocyclic group with the proviso that a monocyclic group formed by A is saturated or partially saturated and that the ring moiety adjacent to the triazolopyrimidine structure in a bicyclic, carbo-cyclic or heterocyclic group is other than carbocyclic aromatic, and A     is optionally substituted by substituents from the group consisting of alkyl, alkoxy, hydroxy, halogen, haloalkyl, NO2, NH2, lower alkylthio, lower alkylsulfonyl, lower alkylsulfinyl, aryl-lower alkyl, amido, carbamoyl, carbalkoxy or aroyl; and pharmaceutically acceptable salts thereof are benzodiazepine agonists/antagonists and anxiomodulating agents, especially those wherein X represents 0, and in addition are adenosine antagonists, anti-asthmatic agents and central nervous stimulating agents, especially those wherein X represents NH or NR. The compounds differ from known triazolo[1,5-c]pyrimidines in the definition of X, R1 or the bridging group A.
Patent CA-1284694-C (CA)
Inventor: LUCAS BENNIE M
IPC: C08L23/10
Filed: 1986-11-12
Granted: 1991-06-04
Abstract: NOVEL POLYOLEFIN COMPOSITIONS                             ABSTRACT    Blends of propylene polymer, ethylene-vinyl acetate copolymer and optionally a synthetic rubber, with small amounts of a polyterpene resin as a compatabilizer, possess excellent properties for the manufacture of heat-sealable and sterilizable films as well as for the manufacture of molded speciality sealed containers and bottles.
Patent CA-1282343-C (CA)
Title: Coated suture
Inventor: RHUM JOSEPH D
IPC: A61L17/00
Filed: 1987-01-28
Granted: 1991-04-02
Abstract: COATED SUTURE   Abstract There is disclosed an improved absorbable surgical suture.  The suture is coated with an absorbable composition consisting of a high molecular weight poly(alkylene oxide).
Patent CA-1334395-C (CA)
Inventor: HARAGUCHI MASATO
IPC: B01D33/21
Filed: 1987-03-12
Granted: 1995-02-14
Abstract: An apparatus for fractionating a cell suspension, which comprises a case body having a substantially columnar space in the interior, which is substantially closed to the outside, a liquid-treating chamber filled with the cell suspension circulating through this liquid-treating chamber, a separating membrane having a separating wall surface having a certain area, which is disposed to separate a predetermined component and allow this component to pass through the separating membrane, a rotary body rotatably arranged in the liquid-treating chamber, a driving mechanism for rotating and driving the rotary body, a cell suspension introduction path, a treated liquid discharge path, and a separated component discharge path.
Patent CA-1294419-C (CA)
Title: Method for making corrosion resistant heat exchangers
Inventor: OTSUKA TATSUO
IPC: B23K1/00
Filed: 1987-09-03
Granted: 1992-01-21
Abstract: ABSTRACT OF THE DISCLOSURE        A method for producing corrosion resistant heat exchangers having a plurality of aluminum tubular elements and fin members, the method comprising immersing the tubular elements in a bath while passing an electric current so that the surfaces thereof are covered with zinc layers of 0.3µm or more in thickness; combining the zinc plated tubular elements with fin members covered with a brazing sheet so that a core is provisionally formed; painting the provisional core with a non-corrosive flux; and placing the provisional core in a furnace to braze the fin members to the tubular elements, and also to enable the zinc layers to diffuse over the surfaces of the tubular elements.
Patent CA-1289388-C (CA)
Inventor: KESSLER THOMAS M
IPC: F16H57/021
Filed: 1987-09-16
Granted: 1991-09-24
Abstract: Title Differential Axle Gear Reduction Housing Abstract of the Invention A one-piece axle housing contains an input shaft, an  intermediate shaft,  a differential gear assembly, and a pair of coaxially arranged axle shafts, all of which  are  aligned  parallel  to  one  another.   The housing  accommodates  either  a  spur  or  helical  gear system, preferably for small off-highway vehicles such as  golf  cars.   In  a  preferred  form,  the  unitary housing is die cast of aluminum and machined according to predetermined specifications.   The  input shaft  is inserted through a motor side of the housing, and is retained by a snap ring.   The  intermediate shaft  is next installed from the bottom of the housing, and the differential and axle shafts are lastly inserted into the housing, which  is then closed by a steel cover. The input shaft, the intermediate shaft, and the axle shafts are maintained parallel to one another by the unitary housing wich includes sets of aligned bores.
Patent CA-1294954-C (CA)
Title: Optically active naphthalene derivatives
Inventor: NAKATSUKA MASAKATSU
IPC: C07C69/92
Filed: 1987-11-25
Granted: 1992-01-28
Abstract: ABSTRACT OF THE DISCLOSURE     The present invention is directed to optically active compounds each containing a naphthalene skeleton, and to liquid crystal compositions which contain the aforesaid optical active compounds, these compositions being suitable for ferroelectric liquid crystal devices having excellent photostability and chemical stability and having a rapid responsivity.      The compounds of the present invention are represented by the general formula          .............   (I) wherein X is a hydrogen atom, a halogen atom, a cyano group, an alkyl group or a methoxy group, latter two groups each having 1 or 2 carbon atoms; and A and B are independently represented by following formula and at least one of them contains an asymmetric carbon atom.                 wherein C and D rings are independent and each of them is a 1,4-phenylene, 2,6-naphthylene, pyrimidine-2,5-diyl, trans-1,4-cyclohexylene, trans-1,3-dioxane-2,5-diyl, trans-1,3-oxathian-2,5-diyl, trans-1,3-dithian-2, 5-diyl or 1,3,2-dioxaborinana-2,5-diyl group; each of m and n is an interger of 0, 1 or 2; each of Z1, Z2, Z3 and Z4 is a bonding group of one or more selected  from the group consisting of a single bond, -C(O)-, -O-, -CH2-, -CH=N-, -CH=CH-, -C?C-, -N=N- and -N(O)=N-; and Y is a hydrogen atom, a halogen atom, a cyano group, a straight-chain or branched alkyl group or an alkenylalkyl group, latter two groups each having 1 to 20 carbon atoms.
Patent CA-1297399-C (CA)
Title: Method and device for separating trimming losses of products formed from sheet
Inventor: TANIDA OSAMU
IPC: B26F3/02
Filed: 1988-01-13
Granted: 1992-03-17
Abstract: ABSTRACT OF THE DISCLOSURE A method and device are provided for separating trimming losses from a sheet having a plurality of products formed thereon with star-shaped scraps between the products.  In one embodiment, the sheet is placed on a sheet supporting plate.  The sheet is positioned between a blanking plate and a plurality of pushing rods fixed to a mounting plate.  Each of the pushing rods has a piercing pin extending from the free end thereof for penetrating into a corresponding star-shaped scrap.  The blanking plate has through holes formed therein which correspond to the pushing rods and star-shaped scraps such that the pushing rod passes through a corresponding through hole.  The inner diameter of each through hole is smaller than the outer size or greatest dimension of the star-shaped scrap.  When the star-shaped scrap is pushed through the through hole by the pushing rod, it deforms and passes through the through hole.  After passing through the through hole, it returns to its original shape and because its outer size is greater than the diameter of the through hole, the star-shaped scrap cannot pass back through the through hole when the pushing rod is drawn back through the through hole.  A collection chamber is positioned on the surface of the blanking plate for collecting the star-shaped scraps pushed through the through holes.  A vacuum system removes the star-shaped scraps from the collection chamber.  Additional embodiments of the method and device are also disclosed.
Patent CA-1277856-C (CA)
Inventor: ST DENIS CARROLL R
IPC: G10D7/02
Filed: 1988-02-19
Granted: 1990-12-18
Abstract: "TUNING APPARATUS FOR STRINGED INSTRUMENTS" A guitar tuner includes a manually graspable body with a head projecting outwardly from one end driven by a motor inside the body to rotate about an axis. The head includes a slot shaped opening for grasping the key of a conventional instrument such as a guitar. An input sensor in the body detects a tone from the string of the instrument and converts it to square wave of the detected frequency. This is compared by a microprocessor with the closest adjacent intended frequency of the instrument selected which acts to drive the motor to tighten or loosen the string as required to attain the required frequency. A digitial display provides a readout of the number and letter of the string concerned. The user can select any one of a number of different states of the device for use with different instruments or different tunings. The user can also override the automatic string selection in cases where the string is a long way from its required frequency.
Patent CA-1308837-C (CA)
Inventor: CYPRIEN GUY
IPC: C08K13/02
Filed: 1988-02-25
Granted: 1992-10-13
Abstract: Diorganopolysiloxane composition capable of being cured to a silicone elastomer by polycondensation reactions, comprising an organic and/or inorganic iodine compound which is liquid or solid at room temperature, nontoxic, soluble in water and which does not inhibit the cure catalyst. 
<??>The compositions cured to elastomer can be employed for water treatment with continuous and controlled release of iodine for the treatment and eradication of the diseases due to an iodine deficiency.
Patent CA-1309619-C (CA)
Title: Underfloor construction of monorail vehicle and method of assembling the same
Inventor: TANI HISASHI
IPC: B61F1/06
Filed: 1988-03-02
Granted: 1992-11-03
Abstract: Abstract The workability during fabrication of an underfloor construction of a monorail vehicle is improved by reducing the steps of fabrication.  An underfloor construction of a monorail vehicle comprises truck enclosures detachably mounted at positions where trucks are mounted in the undersurface of the underframe to enclose the periphery of the trucks, and an enclosure for underfloor equipment for enclosing the sides and lower surface of the underfloor equipment.  A method of assembling an underfloor construction of a monorail vehicle comprises mounting a wiring duct and underfloor equipment on the undersurface of an underframe, conducting wiring work between the wiring duct and the underfloor equipment, and thereafter mounting an enclosure for underfloor equipment.
Patent CA-1287151-C (CA)
Inventor: HINCH MARK G
IPC: H04L12/801
Filed: 1988-03-28
Granted: 1991-07-30
Abstract: PACKET FLOW CONTROL METHOD            Abstract A packet flow control method where delay data are added into an initial packet as it traverses a packet switching network, and where the receiver of the initial packet, rather than the sender, establishes a window size based on such delay data to be used for the duration of a packet connection through the network. The delay data allow for the calculation of an average rather than an instantaneous network delay such that the flow control mechanism is not dependent on the magnitude of network congestion that happens to be present when the connection is first established. Since the receiver determines the window size, the flow control mechanism is put in place as an integral part of the initial packet exchange used to establish the two-way packet connection rather than requiring an additional packet communication to the receiver after a window size calculation by the sender.
Patent CA-1288917-C (CA)
Title: Fibers and filters containing said fibers
Inventor: LARGMAN THEODORE
IPC: D01F6/46
Filed: 1988-04-18
Granted: 1991-09-17
Abstract: IMPROVED FIBERS AND TO FILTERS           CONTAINING SAID FIBERS            ABSTRACT OF THE DISCLOSURE      This invention relates to a fiber comprising a major amount of a continuous phase comprising one or more melt processible polyesters of fiber forming molecular weight, and a minor amount of one or more polyolefins non-uniformly dispersed in said continuous phase such that the concentration of polyolefins at or near the surface of said fiber is greater than the concentration of polyesters at or near the surface of said fiber, and a process for preparing said fiber.
Patent CA-1318969-C (CA)
Title: Encoding of a picture signal in consideration of contrast in each picture and decoding corresponding to the encoding
Inventor: MIZUNO SHOJI
IPC: H04N7/32
Filed: 1988-06-24
Granted: 1993-06-08
Abstract: ABSTRACT OF THE DISCLOSURE:           On encoding an original picture signal comprising signal portions representative of original pictures, respectively, a contrast detecting unit (41) detects a measure of contrast in each picture in response to signal blocks representative of block areas, respectively, which have a common size in the picture in the manner known in transform encoding.  Such measures are variable in a predetermined number of stages. With reference to the stages, a picture encoding parameter determiner (72) determines picture encoding parameters, Supplied with  the encoding parameters, a picture encoder (71) encodes the original picture signal into an encoded picture signal.  Inasmuch as the measures are detected in consideration of the signal blocks, the encoding is carried out on the signal blocks in effect.  The contrast detecting unit, as herein called, preferably divides the pictures into a background region and a picture or non-background region so that the encoding parameters are determined with additional reference to the regions.          The measures may be detected either among the block areas of each picture or among picture elements of each block area. More preferably, a complexity detecting unit is used in addition to the contrast detecting unit.  The picture encoder is typically either a transform encoder or a predictive encoder.
Patent CA-1317951-C (CA)
Title: Substituted n-(3-hydroxy-4-piperidinyl)-benzamides
Inventor: VAN DAELE GEORGES H P
IPC: A61K31/445
Filed: 1988-07-14
Granted: 1993-05-18
Abstract: 1002f                                      JAB 564 ABSTRACT     Novel substituted N-(3-hydroxy-4-piperidinyl)benzamides N-(3-hydroxy-4-piperidinyl)substituted benzamides, their N-oxide forms and pharmaceutically acceptable acid-addition salts having gastro-intestinal motility stimulating properties, compositions containing the same, and methods of treating warm blooded animals suffering from a decreased peristalsis of the gastrointestinal system.
Patent CA-1316284-C (CA)
Title: Epoxide and rubber based curable compositions having good adhesion direct to metal
Inventor: CHASSER ANTHONY M
IPC: C09K3/10
Filed: 1988-09-09
Granted: 1993-04-13
Abstract: Abstract A one package, stable curable composition contains: (a)  a polydiene; (b)  a polyepoxide; (c)  a sulfur and zinc containing vulcanization system adapted to cure the polydiene and the polyepoxide; and (d)  an anhydride containing material effective to promote adhesion of the curable composition to metal. The aforesaid curable composition is suitable for use as an adhesive or sealant.
Patent CA-1335690-C (CA)
Inventor: TAKENOUCHI YOUJI
IPC: C01B17/50
Filed: 1988-09-13
Granted: 1995-05-30
Abstract: A process for producing NH3 and SO2 from ammonium sulfate, which comprises (i) reacting ammonium sulfate with a metal oxide or hydroxide at a temperature of not more than 200 °C to form NH3, water and a metal sulfate and recover-ing NH3, (ii) decomposing the metal sulfate in the presence of a reducing agent to form a metal oxide and SO2 and recovering SO2, and (iii) recycling the metal oxide to step (i) as such or after it is converted to a metal hydroxide.
Patent CA-1306457-C (CA)
Title: Core orientation system
Inventor: FOSTER WILLIAM B
IPC: E21B25/16
Filed: 1988-09-14
Granted: 1992-08-18
Abstract: ABSTRACT     A  core  orientation  device  for  determining  the  in  situ orientation of core samples taken during a drilling process.  A sampling tube having  a plurality  of  equispaced  slots  formed longitudinally  on  its  sidewall  permits  the  scribing  of  a longitudinal line on a core sample within the sampling tube.          The slots for indicating the position of the core within the sampling tube,  a test tube with etch mark to indicate the top point or position of the etch mark within the test tube and a connector for relating the said top point on the test tube to the  longitudinal  slots  on  the  sampling  tube  sidewall  permit determination of the in situ position of the core sample.