baber/WOPTO huggingface dataset:
Patent MX-2019004278-A (MX)
Title: Compounds and methods for the targeted degradation of androgen receptor.
Inventor: CRAIG M CREWS
IPC: C07D401/04
Filed: 2017-10-11
Abstract: The present disclosure relates to bifunctional compounds, which find utility to degrade and (inhibit) Androgen Receptor. In particular, the present disclosure is directed to compounds, which contain on one end a cereblon ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds Androgen Receptor, such that Androgen Receptor is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of Androgen Receptor. The present disclosure exhibits a broad range of pharmacological activities associated with compounds according to the present disclosure, consistent with the degradation/inhibition of Androgen Receptor.
Patent MX-2019005703-A (MX)
Title: Process for material and energy recovery of residues from sugar cane processing and arrangement for performing the process.
Inventor: HANS JOACHIM AUERBACH
IPC: C02F11/04
Filed: 2017-05-09
Abstract: The present invention specifies a technical solution by means of which liquid and solid residues from sugar cane processing are subjected to material and energy recovery while avoiding environmental pollution. For this purpose, proven biotechnological process steps are employed such that the energy potential of biogenic carbon present in the residues is tapped to a large extent and the inorganic plant nutrients present in the residues are preserved predominantly in a form that is available to plants. For this purpose, during sugar cane processing, mixtures of the liquid, finely divided and comminuted solid residues are produced, partly directly recovered during the processing campaign and for recovery outside the processing campaign are siloed in a storage region (8) with a low level of loss. The siloed residue mixtures are subjected to biotechnological recovery in the same way as the fresh residue mixtures. According to the multi-stage biotechnological process of the invention, the residues which are rich in raw fibers and carbohydrate are initially treated in a hydrolysis station (11). The obtained hydrolysates are successively fermented physically separate from each other in different anaerobic environments in a plurality of fermenter stations (12, 13), in each case adapted microcultures being employed and apparatuses known per se being utilized in such a fashion as to guarantee continuous culture.
Patent MX-2019007071-A (MX)
Title: Novel phenyl propionic acid derivatives and uses thereof.
Inventor: JAE- HOON KANG
IPC: C07D417/12
Filed: 2017-12-14
Abstract: The present invention relates to the compounds according to Formula (I), the racemates, enantiomers, diastereomers thereof or pharmaceutical acceptable salts thereof, or pharmaceutical compositions comprising these, for the treatment or prevention of metabolic disorders. The compounds according to Formula (I) are, as GPR40 agonists, available for oral administration with glucose-dependent insulin secretion mechanism, which exhibit excellent glucose lowering efficacy without the risk of hypoglycemia. Thus, the compounds and/or pharmaceutical compositions comprising the compounds as effective components are useful in treating and/or preventing symptoms of type 2 diabetes through adequate control of blood glucose.
Patent MX-2019009740-A (MX)
Title: Beverage preparation and infusion system.
Inventor: MASSIMILIANO VALSECCHI
IPC: A47J31/36
Filed: 2018-02-14
Abstract: A machine is provided for preparing a desired beverage product from infusible materials. The machine includes a brew chamber that is adapted to hold the infusible materials, the brew chamber having an inlet and an outlet. An inlet tube is provided for transferring a fluid from a fluid receptacle to the inlet of the brew chamber and a dispensing tube is provided for transferring fluid from the outlet of the brew chamber to the receptacle. A fluid pump is provided for recirculating fluid through the brew chamber. In another aspect, a machine is provided for preparing a desired beverage product containing a gas. The machine includes a fluid pump for recirculating fluid from a fluid receptacle through an inlet tube to a dispensing tube and back to said fluid receptacle. The machine further includes an air pump disposed between the inlet tube and the fluid pump for introducing air into said beverage fluid that is recirculated by said fluid pump. A pod for use with the machine is also provided.
Patent MX-2019010507-A (MX)
Title: Continuous volume measurements in liquid receptacles.
Inventor: GONZALEZ FLORES CARLOS MANUEL
IPC: B65D90/00
Filed: 2019-09-04
Abstract: The present invention is about a volume measuring device installed inside a box used to store liquid. The measuring device is placed at the bottom of the liquid delivery box, and displays via a measurement tower a measure of the volume still in the box. The device is comprised of a receptacle or sealed bag connected to the measurement tower. As the pressure of the liquid weight changes, the receptacle reacts by moving a gauge marker that reflects such changes, thus measuring the current volume of liquid in the shipper.
Patent MX-2019014245-A (MX)
Title: Hot stamp member.
Inventor: KAZUHISA KUSUMI
IPC: C22C38/38
Filed: 2018-06-01
Abstract: The hot stamp member according to the present invention comprises a steel material, an Al-Fe intermetallic compound layer formed on the steel material, and an oxide film layer formed on the Al-Fe intermetallic compound layer. The oxide film layer includes: one or more group A elements selected from the group consisting of Be, Mg, Ca, Sr, Ba, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, and Zn; Al; oxygen; and impurities. The ratio of the group A element(s) excluding the oxygen in the oxide film layer is 0.01-80 at%, and the thickness t of the oxide film layer is 0.1-10.0 µm. When the group A element(s) in the oxide film layer is measured in the thickness direction from the surface of the oxide film layer by using GDS, the maximum value of the detected intensity of the group A element(s) in the range of 1/3 times the thickness t from the surface is 3.0 times or more of the average value of the detected intensity of the group A element(s) in the range from 2/3 times the thickness t to the thickness t.
Patent MX-2019015931-A (MX)
Title: Dental impression kit and methods therefor.
Inventor: KATZMAN JORDAN
IPC: A61C19/00
Filed: 2018-06-20
Abstract: A method of administering the contents of a dental impression kit includes sending a dental impression kit to a user where the dental impression kit includes a container containing an initial dental assembly, a redundant dental assembly, and a dental appliance. The initial and redundant dental assemblies include dental trays and putty where the putty is provided in a sufficient amount to be positioned in the dental trays for creating dental impressions. The dental appliance is configured to hold open the user's lips to permit visualization of the user's teeth. The method includes instructing the user to utilize the dental appliance, and administer the initial and redundant dental assemblies to create the dental impressions, which provide information necessary to manufacture a plurality of dental aligners specific to the user and being configured to reposition one or more teeth of the user.
Patent MX-2020000618-A (MX)
Title: Pharmaceutical composition.
Inventor: ROBERGE CHRISTOPHE
IPC: A61K31/5415
Filed: 2018-07-17
Abstract: The present invention provides a biodegradable drug delivery composition comprising: (i) a mixture of at least three different block copolymers, wherein each block copolymer is: (a) a biodegradable triblock copolymer having the formula: A<sub>v</sub>-B<sub>w</sub>-A<sub>x</sub> wherein A is a polyester and B is polyethylene glycol and v and x are the number of repeat units from 1 to 3,000 and w is the number of repeat units from 3 to 300 and v=x or vâ x; or (b) a biodegradable diblock copolymer having the formula: C<sub>y</sub>-A<sub>z</sub> wherein A is a polyester and C is an end-capped polyethylene glycol and y and z are the number of repeat units with y = 2 to 250 and z = 1 to 3,000; and wherein the mixture comprises at least one (a) and at least one (b); and the weight ratio between (a) and (b) is 1:19 to 5:1; and (ii) at least one pharmaceutically active ingredient.
Patent MX-2020000806-A (MX)
Title: Composition for use in the prevention and treatment of pathologies of the cardiovascular apparatus.
Inventor: LACORTE ANDREA
IPC: A61K33/26
Filed: 2018-07-26
Abstract: The present invention relates to a composition comprising or, alternatively, consisting of an effective amount of a mixture comprising at least (a) one lipophilic vitamin, or analogues and derivatives thereof, (b) one magnesium salt and (c) one iron (I II) oxide, complex or salt for use in a preventive or curative method for treating cardiovascular disorders and pathologies.
Patent MX-2020001407-A (MX)
Title: Ultrahigh efficiency spray drying apparatus and process.
Inventor: BEETZ CHARLES PERSHING
IPC: B01D1/18
Filed: 2018-08-04
Abstract: Ultrahigh efficiency spray drying systems and processes, utilizing induction of localized turbulence in a drying fluid flow stream to produce spray dried product, having particular utility for low temperature spray drying operations. A method of processing a spray dryable liquid composition to form a spray dried product includes: generating a spray of the spray dryable liquid composition; contacting the spray of spray dryable liquid composition in a spray drying contact zone with a stream of primary drying fluid; injecting pressurized secondary drying fluid into the stream of primary drying fluid in the spray drying contact zone at multiple loci thereof to provide localized turbulence at said multiple loci; and recovering the spray dried product from the spray drying contact zone. Systems of the present disclosure are effective in achieving high-rate production of dry powder spray dried products, with substantially reduced capital equipment costs, energy requirements, and operating expenditures.
Patent MX-2020005587-A (MX)
Title: An apparatus for soldering a terminal on window glass for a vehicle and a method thereof.
Inventor: HEO UN HAENG
IPC: H01R43/02
Filed: 2018-11-30
Abstract: The present invention provides an apparatus for soldering a terminal to which a solder alloy is attached on window glass for a vehicle, the apparatus comprising: a terminal to which the solder alloy is attached; a coil unit comprising a coil which generates induction heat; a gripper which grips and releases the terminal and is configured to be movable upward and downward relative to the coil unit in a state of gripping the terminal; and a ferrite core unit comprising a ferrite core which is configured to be surrounded by the coil unit to receive the induction heat, and is configured to be movable upward and downward relative to the coil unit, wherein the solder alloy attached to the terminal, in a state of being in contact with the window glass, is melted by the induction heat from the coil unit and the ferrite core unit such that the terminal is attached to the window glass.
Patent MX-2020007602-A (MX)
Title: Shock-absorbing member.
Inventor: SUZUKI TOSHIYA
IPC: B62D25/16
Filed: 2019-01-28
Abstract: [Problem] To absorb shock at time of collision even in the absence of a large interior space near the vehicle exterior. [Solution] This shock-absorbing member comprises: an exterior material 110 for an automobile; a first reinforcing member 122 that is disposed adjacent to the exterior material 110 and whose cross section orthogonal to the extending direction has a height, in the direction orthogonal to the exterior material 110, that is greater than the width in the direction along the exterior material 110; a second reinforcing member 124 that is disposed adjacent to the exterior material 110 and whose cross section orthogonal to the extending direction has a height, in the direction orthogonal to the exterior material 110, that is greater than the width in the direction along the exterior material 110; an intersecting part where the first reinforcing member 122 and the second reinforcing member overlappingly intersect; and a joint that joins the first reinforcing member 122 and the second reinforcing member 124 at the intersection.
Patent MX-2020008635-A (MX)
Title: Method for improving quality of aquaculture pond water using a nutrient germinant composition and spore incubation method.
Inventor: GILLESPIE KELLY
IPC: A01K61/13
Filed: 2019-01-31
Abstract: A method for improving the quality of pond water used in aquaculture applications by adding to the pond water active bacteria that are preferably germinated from spores on site using a nutrient-germinant composition and an incubation method for increased spore germination efficiency, in combination with a nitrification enhancement agent such as calcium carbonate or calcified seaweed, and an optional reaction surface area modifier such as calcified seaweed or plastic or metal particles or fragments. The nutrient-germinant composition comprises L-amino acids, D-glucose and/ or D-fructose, a phosphate buffer, an industrial preservative, and may include bacteria spores (preferably of one or more Bacillus species) or they may be separately combined for germination. The incubation method comprises heating a nutrient germinant composition and bacteria spores, to a temperature range of 35Â°C to 60Â°C for around 2 to 60 minutes to produce an incubated bacteria solution that is discharged to the aquaculture application.
Patent MX-2020010386-A (MX)
Title: Blood sample management using open cell foam.
Inventor: IVOSEVIC MILAN
IPC: B01L3/02
Filed: 2016-08-11
Abstract: A specimen mixing and transfer device adapted to receive a sample is disclosed. The specimen mixing and transfer device includes a housing, a material including pores that is disposed within the housing, and a dry anticoagulant powder within the pores of the material. In one embodiment, the material is a sponge material. In other embodiments, the material is an open cell foam. In one embodiment, the material is treated with an anticoagulant to form a dry anticoagulant powder finely distributed throughout the pores of the material. A blood sample may be received within the specimen mixing and transfer device. The blood sample is exposed to and mixes with the anticoagulant powder while passing through the material.
Patent MX-2020012487-A (MX)
Title: Reprocessing of polymeric compositions.
Inventor: MANO BARBARA IRIA SILVA
IPC: C08L23/08
Filed: 2019-04-19
Abstract: A method may include reprocessing a polymer composition comprising a crosslinked polymeric composition, wherein the crosslinked polymeric composition comprises a matrix polymer having a polar polymer internal phase that is selectively crosslinked with a crosslinking agent, wherein the reprocessed polymer composition retains an environmental stress cracking resistance within 60% of the value for the initial polymer composition when measured according to ASTM D-1693 procedure B and wherein the reprocessed polymer composition presents a Normalized Property Balance Index (N<sub>PBI</sub>) greater than about 1.0.
Patent MX-2020012567-A (MX)
Title: Anti-ox40 antibodies and methods of use.
Inventor: ZHANG TONG
IPC: A61P35/00
Filed: 2019-05-22
Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that bind to human OX40 (ACT35, CD134, or TNFRSF4), a pharmaceutical composition comprising said antibody, and use of the antibody or the composition for treating a disease, such as cancer. In particular, the anti-OX40 antibody of the present invention does not interfere with the binding of OX40-ligand to its receptor.
Patent MX-2020012954-A (MX)
Title: Sorghum cytoplasmic male sterility markers and loci.
Inventor: HESSEL DAVID ALAN
IPC: A01H5/10
Filed: 2019-05-30
Abstract: Various methods and compositions are provided for identifying and/or selecting a sorghum plant or germplasm with or without a cytoplasmic male sterility (CMS) trait. In certain embodiments, the method comprises detecting at least one allele of one or more marker locus within or linked to a QTL associated with CMS. In further embodiments, the method comprises crossing a selected sorghum plant with a recurrent sorghum parent plant and selecting progeny with CMS.
Patent MX-2021001083-A (MX)
Title: Dosing regimen for bcma-cd3 bispecific antibodies.
Inventor: MUNZERT GERD
IPC: A61K39/00
Filed: 2019-07-30
Abstract: The present disclosure relates to an antibody construct comprising a first domain which binds to BCMA and a second domain which binds to CD3, for use in the treatment or amelioration of a BCMA positive neoplasm, wherein the antibody construct is administered at a specified dose in at least one cycle, wherein one cycle comprises a specified period of administration of the antibody construct. Moreover, the disclosure relates to a method for the treatment of a BCMA positive neoplasm comprising administering a specified amount of such antibody construct, and the use of such antibody construct for the manufacture of a medicament for the treatment of a BCMA positive neoplasm.
Patent MX-2021003228-A (MX)
Title: Connectors for infusion pump feeding sets.
Inventor: O'KEEFE CHRISTOPHER
IPC: A61M1/00
Filed: 2019-09-17
Abstract: Improved feeding set connectors and cassettes are disclosed for use with peristaltic infusion pumps for safely delivering enteral nutritional fluids to a patient. The connectors provide an easy to use "pump-to-set" integration or "keying" system for specific reusable infusion pumps and their matching feeding sets, and can be utilized by medical professionals having various skill levels. The inventive feeding set cassettes can prevent accidental free flow of enteral fluids into a patient, even upon inadvertent release of the connector from the pumping mechanism.
Patent MX-2021008088-A (MX)
Title: Embossing or debossing of a label substrate.
Inventor: MCKILLIP BARRON G
IPC: G09F3/02
Filed: 2020-02-12
Abstract: A label as shown and described herein. The label may include a label substrate, an adhesive adjacent the substrate, and a liner adjacent the adhesive, such that the adhesive is disposed between the label substrate and the liner, and wherein the label substrate is embossed or debossed, and the liner is not embossed or debossed.
Patent MX-2021012713-A (MX)
Title: Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives.
Inventor: SKRANC WOLFGANG
IPC: C07C213/00
Filed: 2020-04-08
Abstract: The present invention relates to a new process for the production of substituted 2-[2-(phenyl) ethylaminojalkaneamide derivatives of the following formula (I), in particular 2-[2-(3-butoxyphenyl)-ethylamino]-N,N-dimethylacetamide in high yields with very high chemical purity. The invention relates to a process for preparing a compound of formula (I) or a pharmaceutically acceptable salt thereof:.
Patent MX-2021013113-A (MX)
Title: Formation of concrete monuments.
Inventor: MEEKS EDDIE ALEXANDER
IPC: B44C1/28
Filed: 2021-10-26
Abstract: A kit for forming a monument includes a back plate having a top surface, a plurality of tiles each having a face with a symbol embossed on the face configured to be selectively placed on the top surface of the back plate, and a frame perimeter sized to match the back plate to form a cavity. The tiles can be placed in positions on the upper surface of the back plate, the perimeter frame can be attached to the back plate, and a castable material can flow into the cavity, where the castable material can harden. The perimeter frame, back plate and tiles can then be removed from the hardened castable material, leaving a hardened material with a surface having a recess formed by the raised symbol.
Patent MX-2021013546-A (MX)
Title: Dynamic routing of vehicles through established corridors.
Inventor: LI LI
IPC: G06Q50/30
Filed: 2020-05-08
Abstract: A computing system can assign a transport request to a high capacity vehicle (HCV) corridor of a plurality of HCV corridors, where the HCV corridor is associated with a plurality of possible rendezvous locations and a plurality of possible routes that can be traveled by individual HCVs. The computing system can determine, from the transport request of the requesting user, an optimal pick-up location from the plurality of possible rendezvous locations of the HCV corridor for an HCV to rendezvous with the requesting user.
Patent MX-2022001723-A (MX)
Title: Cbd formulations and uses thereof.
Inventor: WILSON GLYNN
IPC: A61K9/00
Filed: 2020-08-07
Abstract: Provided herein are formulations including a cannabinoid and N-L-alpha-aspartyl-L-phenylalanine 1-methyl ester (APM). Also provided are methods of using the formulations.
Patent MX-2022005186-A (MX)
Title: Systems and methods for sample preparation.
Inventor: ROTHBERG JONATHAN M
IPC: C12Q1/6806
Filed: 2020-10-28
Abstract: Methods and devices for isolating or enriching target molecules from a sample using lysis, fragmentation and affinity purification, e.g., using scodaphoresis, are provided herein. In particular embodiments, a device for enriching a target molecule from a biological sample is characterized in that the device comprises an automated sample preparation module comprising a cartridge housing that is configured to receive a removable cartridge. In some embodiments, methods and devices further involve detection, analysis and/or sequencing of a target molecule.
Patent MX-2022005614-A (MX)
Title: Retainer sleeve design with external ribs or with an anti-rotaional feature.
Inventor: SERRURIER DOUGLAS C
IPC: E02F9/28
Filed: 2020-10-28
Abstract: A retainer sleeve (600) includes an at least partially annular body (402) defining an axis of rotation (404), a radial direction (406), and a circumferential direction (408). The body (402)may also have a radially inner annular surface (410) defining a radially inner aperture (413), and a first anti-rotation feature (412) extending radially inwardly from the radially inner annular surface (410) including a sloping ledge (414) having a locking surface (416), and an outer peripheral surface (662) defining a notch (666) that is at least partially aligned with the first anti-rotation feature (612) or an array of a plurality of external ribs (664) extending outwardly radially from the outer peripheral surface (662).
Patent MX-2022005817-A (MX)
Title: Methods of manufacturing car-t cells.
Inventor: YU HUI
IPC: C12N5/0783
Filed: 2020-11-13
Abstract: Aspects of the present disclosure relate to methods for manufacturing genetically engineered T cells expressing a chimeric antigen receptor (CAR) that provide several improvements over conventional manufacturing methods, thereby enabling production of a robust supply of clinically useful CAR T-cell therapies.
Patent MX-2022007551-A (MX)
Title: Surfactants for agricultural products.
Inventor: ASIRVATHAM EDWARD
IPC: A01N25/30
Filed: 2020-12-10
Abstract: Agricultural products, such as pesticides, plant growth regulators, fungicides, herbicides, and insecticides, may be formulated to include one or more surfactants, from one or more surfactant classes, such as siloxane derivatives of amino acids that have surface-active properties.
Patent MX-2022013186-A (MX)
Title: Protein polyurethane alloys and layered materials including the same.
Inventor: CAI SHAOBO
IPC: C08L9/00
Filed: 2021-04-30
Abstract: Protein polyurethane alloys including one or more proteins dissolved within one or more polyurethanes. The protein polyurethane alloy may have one or more mechanical properties that are superior to the polyurethane in the absence of protein. The protein polyurethane alloys may be incorporated into a layered material including one or more protein polyurethane alloy layers.