baber/WOPTO huggingface dataset:
Patent NZ-511188-A (NZ)
Title: N-(iminomethyl)amine derivatives useful as NO synthase inhibitors
Inventor: CHABRIER DE LASSAUNIERE PIERRE
IPC: A61P25/28
Filed: 1999-09-22
Abstract: An N-(iminomethyl)amine derivative or its pharmaceutically acceptable salt has the formula (I) A-X-Y-G-N=C(B)-NH2 wherein: G is optionally substituted phenylene; A is i) a group of formula (II); W is sulphur; R1 to R5 are independently hydrogen, halogen, -OH, alkyl, alkoxy, -CN, -NO2 or NR6R7 and R11 is hydrogen, -OH, -COR12, alkyl or alkoxy or ii) A is group of formula (III); W is absent or is a bond, O, S or NR15 and R1 to R5 are as defined above; B is -CH2-NO2, alkyl, 5 to 6 membered carbocyclic aryl or heterocyclic aryl containing 1 to 4 heteroatoms selected from oxygen, sulphur and nitrogen or NR13R14; R13 and R14 are independently hydrogen, alkyl, -CN, -NO2 or together with the nitrogen to which they are attached form a 5 to 6 membered non-aromatic heterocycle with the ring members selected from -CH2, -NH-, -O- and -S-; X is a bond, -(CH2)k-NR16-, -O-, -S-, -CO-, -NR16-CO, -CO-NR16, -O-CO-, -CO-O-, -NR16-CO-O- or -NR16-CO-NR17; k is 0 or 1; Y is a bond, -(CH2)m-, -(CH2)m-O-(CH2)n-, -(CH2)m-S-(CH2)m-, -(CH2)m-NR18-(CH2)n, -(CH2)m-NR18-CO-(CH2)n-, -(CH2)m-CO-NR18-(CH2)n- or -(CH2)m-Q-(CH2)n-; Q is piperazine, homopiperazine, 2-methylpiperazine, 2,5-dimethylpiperazine, 4-oxypiperidine or 4-aminopiperidine; m and n are independently 0 to 6 and R6, R7, R8, R9, R10, R12, R15, R16, R17 and R18 are as defined in the specification. The compounds are useful as NO synthase inhibitors.
Patent NZ-515088-A (NZ)
Title: Method for producing L-phosphinothricine by enzymatic transamination with aspartate
Inventor: BARTSCH KLAUS
IPC: C12P1/04
Filed: 2000-03-30
Abstract: Described is a method for the enzymatic, chiral synthesis of L-phosphinothricine by means of transamination from a corresponding keto acid PPO with aspartate as aminodonor. Quantitative conversion can be obtained by means of suitable reaction engineering using approximately equimolar amounts of amino donor and aminoacceptor, whereby the donor amino acid aspartate is completely used. The use of thermostable transaminases enables high reaction velocity and correspondingly high room/time efficiencies.
Patent NZ-518237-A (NZ)
Title: Desulfurization and novel sorbents for same
Inventor: KHARE GYANESH P
IPC: B01J23/06
Filed: 2000-10-18
Abstract: A process for the removal of sulfur from a stream of a cracked-gasoline or a diesel fuel which comprises: (a) contacting said stream with a sorbent composition comprising zinc titanate, and a metal, metal oxide or metal oxide precursor promoter wherein said metal is selected from the group consisting of cobalt, nickel, iron, manganese, copper, molybdenum, tungsten, silver, tin and vanadium and mixtures thereof and wherein said promotor metal is present in a substantially reduced valence state of two or less and in an amount which will effect the removal of sulfur from a stream of cracked-gasoline or diesel fuel when contacted with said sorbent composition under desulfurization conditions, such contacting being carried out in a desulfurization zone under conditions such that there is formed a desulfurized fluid stream of cracked-gasoline or diesel fuel and a sulfurized sorbent; (b) separating the resulting desulfurized fluid stream from said sulfurized sorbent; (c) regenerating at least a portion of the separation sulfurized sorbent in a regeneration zone so as to remove at least a portion of the sulfur absorbed thereon; (d) reducing the resulting desulfurized sorbent in an activation zone so as to provide a reduced valence state of two or less metal promotor content therein which will affect the removal of sulfur from a stream of a cracked-gasoline or diesel fuel when contacted with same; and thereafter (e) returning at least a portion of the resulting desulfurized, reduced sorbent to said desulfurization zone.
Patent NZ-520824-A (NZ)
Title: Use of CDP-choline for before the onset of a cerebral ischemic episode
Inventor: FOGUET RAFAEL
IPC: C07H19/10
Filed: 2001-03-13
Abstract: The application describes the prophylactic treatment of cerebral ischemia utilising CDP-Choline in the manufacture of a medicament for the treatment of patients who have undergone major surgery or are at risk of suffering an acute ischemic event. Subjects exposed to stimulants, particularly cocaine are excluded from this treatment.
Patent NZ-525418-A (NZ)
Title: Oral preparation for reducing, e.g., bacterial, atherosclerotic and pleural plaque; dental, renal, biliary and prostatic calculus comprising Ascophyllum seaweed or extract thereof
Inventor: WIKNER SUNE
IPC: A61K8/97
Filed: 2001-09-27
Abstract: An oral preparation for reduction of mammalian, e.g. human, cat or dog, plaque and/or calculus, such as bacterial plaque, arteriosclerotic plaque, atherosclerotic plaque, pleural plaque, dental calculus, renal calculus, biliary calculus, and prostatic calculus. The preparation contains an Ascophyllum sp., especially A. nodosum, seaweed or an extract thereof. The oral preparation is suitable for use in prophylactic and/or therapeutic method of treating plaque and/or calculus in a mammal.
Patent NZ-526608-A (NZ)
Title: Method for preparing submicron particle suspensions
Inventor: KIPP JAMES E
IPC: A61K47/14
Filed: 2001-12-20
Abstract: A method for preparing submicron sized particles of a pharmaceutically-active compound, the solubility of which is greater in a water-miscible first solvent than in a second solvent which is aqueous is disclosed, wherein the process comprises the steps of: (i) dissolving the pharmaceutically-active compound in the water-miscible first solvent to form a solution, the first solvent being selected from the group consisting of N methyl-2-pyrrolidinone, 2-pyrrolidone, dimethyl sulfoxide, dimethylacetamide, lactic acid, methanol, ethanol, isopropanol, 3-pentanol, n-propanol, glycerol, butylene glycol, ethylene glycol, polypropylene glycol, mono- and diacylated monoglycerides, dimethyl isosorbide, acetone, dimethylformamide, 1,4-dioxane, ethyl acetate, propyl acetate, polyethylene glycol, polyethylene glycol esters, polyethylene glycol sorbitans, polyethylene glycol monoalkyl ethers, polypolypropylene glycol, polypropylene alginate, polypolypropylene glycol-10 butanediol, polypolypropylene glycol-10 methyl glucose ether, polypolypropylene glycol-20 methyl glucose ether, polypolypropylene glycol-15 stearyl ether, polypolypropylene glycol dicaprylate, polypropylene glycol dicaprate, polypropylene glycol laurate; (ii) mixing the solution with the second solvent to define a pre-suspension; and (iii) adding energy to the pre-suspension to form particles having an average effective particle size of less than about 2 micron, and said adding energy step comprises homogenization, counter-current flow homogenization, microfluidization or sonication.
Patent NZ-531359-A (NZ)
Title: Tine for a soil cultivating apparatus
Inventor: THIAN LINDSAY PETER
IPC: A01B35/06
Filed: 2004-02-24
Abstract: Disclosed is an elongate one-piece tine (10) for a soil cultivating implement, wherein the longitudinal centerline of the tine lies substantially in a plane of the tine. The tine includes an arcuate portion (15) having a re-entrant portion at a first end thereof, the cross section of the spring portion being relatively thin in the plane of the tine and elongate perpendicular to the plane of the tine, a mounting portion (16) fixed to the re-entrant portion and adapted for mounting the tine to the implement, a shank portion (14) having a foot (17) for receiving a ground-engaging point, the shank portion fixed to a second end of the spring portion, characterized in that the cross section of the shank is elongate in the plane of the tine.
Patent NZ-532774-A (NZ)
Title: Nutritional supplements and methods for prevention, reduction and treatment of radiation injury
Inventor: ROSENBLOOM RICHARD A
IPC: A61K41/00
Filed: 2002-05-01
Abstract: Disclosed is a nutritional supplement composition for the prevention, reduction or treatment of radiation injury due to exposure to ionizing radiation. The composition includes: one or more compounds that regulates cell differentiation and/or cell proliferation, such as vitamin D3, 1(S),3(R)-dihydroxy-20(R)-(1-ethoxy-5-ethyl-5-hydroxy-2heptyn-1-yl)-9,10-seco-pregna-5(Z),7(E),10(19)-triene, compounds that may be converted or metabolized into vitamin D3 in the human body, metabolites thereof, and pharmaceutically acceptable salts thereof, and one or more antioxidants such as alpha-lipoic acid and chlorophyllin or pharmaceutically acceptable salts thereof; optionally formulated in a pharmaceutically acceptable carrier for an oral composition. The composition may further include optional ingredients such as flavonoids, flavonoid derivatives, selenium, selenium compounds, anti-inflammatories, organic germanium, Korean ginseng, American ginseng, Siberian ginseng and B-complex vitamins. A method for the administration of an oral composition for the purpose of preventing, reducing or treating radiation injury involves orally administering an effective amount of a composition including one or more compounds that regulates cell differentiation and/or cell proliferation, and one or more antioxidants to a person before, during or after radiation exposure. A method for the topical administration of the composition for the purpose of preventing, reducing or treating radiation injury involves topically administering an effective amount of the composition to an area of skin, which has been or will be exposed to ionizing radiation. The compositions and methods can be employed to prevent, reduce or treat radiation injury caused by a wide variety of types of radiation exposure.
Patent NZ-535467-A (NZ)
Title: Tick chitinase and methods for treating or preventign tick-borne infection
Inventor: NAGASAWA HIDEYUKI
IPC: A61K35/56
Filed: 2003-02-28
Abstract: A polypeptide consisting of the amino acid sequence of SEQ ID NO:2 exhibits chitinase activity. Also described are polynucleotides, vectors, transformants and antibodies. The polypeptides, polynucleotides and vectors are useful in pharmaceutical compositions for exterminating ticks and treating or preventing a tick-borne infection.
Patent NZ-537840-A (NZ)
Title: Modafinil polymorphic forms and methods for their preparation
Inventor: COURVOISIER LAURENT
IPC: A61P25/16
Filed: 2003-08-08
Abstract: Disclosed herein are modafinil polymorphic forms, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic forms.
Patent NZ-537915-A (NZ)
Title: Laundry appliance utility shelf
Inventor: CAREY MICHAEL R
IPC: D06F39/12
Filed: 2005-01-26
Abstract: A laundry appliance having a cabinet enclosing a laundry treating mechanism, the cabinet having an open-able door in a vertical front face thereof, is provided with a shelf recessed in the cabinet and arranged to be extendable to a horizontal position in an embodiment a predetermined distance below the door sufficient to allow a laundry basket to be placed on the shelf when extended and to allow the door to be opened and closed with the basket on the extended shelf and in an embodiment to provide a step for a user.
Patent NZ-538332-A (NZ)
Title: Double skin door apparatus
Inventor: CRITTENDEN JERRY
IPC: E06B3/78
Filed: 2003-08-20
Abstract: A hollow core door (10) comprises a perimeter frame (12), and first and second molded skins (30, 50). Each skin has an exterior surface (31, 51) and an interior surface (33, 53) secured to opposing sides of the frame (12). At least one of the skins (30, 50) has an outer planar area (32, 52), an inner planar area (38, 58), and an asymmetric profile surrounding the inner planar area (38, 58) and interconnecting and integral with the outer planar area 32, 52) and the inner planar area (38, 58). The asymmetric profile area has a convex portion (34, 54) extending outwardly from and relative to the plane of the outer planar area (32, 52).
Patent NZ-540196-A (NZ)
Title: Camelidae antibodies against imminoglobulin E and use thereof for the treatment of allergic disorders
Inventor: SILENCE KAREN
IPC: G01N33/577
Filed: 2003-11-07
Abstract: Disclosed is a composition for oral administration, comprising a therapeutically effective amount of a polypeptide construct comprising one or more single domain antibodies directed to one or more target molecules and a pharmaceutical acceptable ingredient, such that the, or at least one, single domain antibody is a functional single domain antibody selected from the group consisting of Camelidae VHH, humanized SamelidaeVHH and a camelized single domain antibody
Patent NZ-541231-A (NZ)
Title: A method of treatment or prophylaxis of symptoms of herpes viral infection
Inventor: MCGREGOR NEIL
IPC: A61P31/22
Filed: 2004-01-09
Abstract: Disclosed is the use of a composition comprising a citrate salt and/or a succinate salt, and an amino acid selected from valine, aspartic acid, leucine, isoleucine, alanine, lysine, taurine and asparagine in the manufacture of a medicament for the treatment and/or prophylaxis of one or more symptoms of herpes viral infection in a subject wherein said citrate salt is sodium citrate, potassium citrate or magnesium citrate and wherein said succinate salt is sodium succinate, potassium succinate, calcium succinate or magnesium succinate.
Patent NZ-541489-A (NZ)
Title: Topically applied vasoconstrictor for treatment in cardic catheterization complications
Inventor: VOURNAKIS JOHN N
IPC: A61B17/00
Filed: 2003-12-31
Abstract: Disclosed is the use of a composition comprising an effective amount of one or more vasoconstrictor for the manufacture of a medicament for treating a breach or puncture in a vein or artery resulting from a cardiac catheterization procedure in a patient, wherein the vasoconstrictor does not comprise a poly-B-1Ó4 N-acetylglucosamine polymer or derivative thereof, wherein said medicament is for topical application over a catheter exit site on the skin of a patient in need of such treatment, wherein the catheter exit site is contiguous with the breach or puncture in the vein or artery by 1-10 cm, and wherein compression is concurrently applied to the breached or punctured vein or artery. Further disclosed are medicaments for the treating a breach or puncture in a femoral artery resulting from a cardiac catheterization procedure in a patient, decreasing the occurrence of localized vascular complications in a patient and inhibiting the formation of hematomas resulting from a cardiac catheterization procedure in a patient.
Patent NZ-542176-A (NZ)
Title: Control release formulation containing a hydrophobic material as the sustained release agent
Inventor: MULYE NIRMAL
IPC: A61K9/20
Filed: 2003-03-04
Abstract: Disclosed is a sustained release pharmaceutical composition in tablet form comprising a core comprising pharmaceutically effective amount of a medicament and a hydrophobic material as the sustained release agent, said medicament being present in an amount greater than about 25% of the pharmaceutical composition and having a water solubility less than about 1 gram per 10 mL of water at 25 degree C and 1 atm, and more than about 100 mg per 1 liter of water at 25 degree C and 1 atm, said hydrophobic material having a melting point ranging from at least about 40 degree C to about 100 degree C at 1 atm pressure, and being present in an amount ranging from about 3% to less than about 20% by weight of the pharmaceutical composition and in an amount by weight less than that of the medicament, provided that a polymer capable of swelling that causes disintegration of the tablet, and high concentrations of water-soluble low molecular weight excipient, are excluded from the core. Also disclosed is a method of preparing the above described composition, which comprises (a) blending a medicament and a hydrophobic material and optionally a lubricant and optionally an excipient and optionally an adjuvant polymer to form a substantially homogenous and uniform blend, (b) compressing the product of step (a) to form a tablet thereof, said pharmaceutical composition being formed in the absence of melting the hydrophobic material or utilizing a high shear mixer or by heating to temperatures slightly below the melting point of the hydrophobic material.
Patent NZ-545585-A (NZ)
Title: Apparatus for, and methods of, disposing of tyres
Inventor: LACEY D ARCY SHANE
Filed: 2006-02-27
Abstract: Methods and apparatus for disposing of tyres are disclosed. The apparatus (30) may be mounted on a support structure at the mounting formation (34) of a body member (32). A cutting assembly (46) is adjustably supported by a bracket (48) of the body member. The cutting assembly has a shaft that is axially and rotatably displaceable relative to the bracket, a control member (52) at one end of the shaft, and a cutting unit (53) for cutting the tyre at the other end of the shaft. The control member effects positional variation of the cutting unit relative to the body member.
Patent NZ-546282-A (NZ)
Title: Standard configurable universal serial bus (USB) device identifier
Inventor: PAYNE STEPHEN R
IPC: G06F3/00
Filed: 2004-09-02
Abstract: A USB peripheral device belonging to a model line of identical peripheral devices. The peripheral device includes a USB interface enabling connection of the peripheral device to a USB port of a host device. The peripheral device also includes a memory for storing a USB device identifier. The USB device identifier comprises a standard USB device identifier that is the same for all the peripheral devices of the model line. The standard USB device identifier identifies each peripheral device in the model line to the host device as identical devices, thereby preventing device driver reinstallation and communication port reassignment when swapping one peripheral device for another peripheral device from the same model line. This enables identical peripheral devices to be "hot-swappable" such that they can be interchanged on the host device, even when the host device is powered up and running. Corresponding methods are also provided.
Patent NZ-552718-A (NZ)
Title: Use of meloxicam in veterinary medicine for the treatment of inflammatory painful diseases
Inventor: FRITON GABRIELE
IPC: A61K31/5415
Filed: 2005-06-11
Abstract: Disclosed is the use of a formulation containing meloxicam or a pharmacologically acceptable meloxicam salt of an organic or inorganic base and one or more vehicles for preparing a veterinary medical composition having analgesic efficacy for the treatment of mild or moderate mastitis. Also disclosed is a method of treating mild or moderate mastitis in a non-human animal comprising administering a veterinary medical composition having analgesic efficacy comprising said formulation.
Patent NZ-554037-A (NZ)
Title: Pentacyclic anti-tumour compounds with angeloyl groups and optional sugar moieties
Inventor: CHAN PUI-KWONG
IPC: A01N43/16
Filed: 2005-09-07
Abstract: Disclosed is the use of a compound of formula (5), or a salt or ester thereof, wherein the substituents are as defined in the specification, for treating ovarian cancer. Also disclosed are new compounds of the same formula and uses thereof. Also discloses is a method for isolating the above compounds from Xanthocera sorbifolia herb or plants from the sapindaceae family.
Patent NZ-556466-A (NZ)
Title: Sealing of polyethylene or polypropylene containers using blow-fill-seal method and a metal coating
Inventor: MCAFFER IAN GARDNER CAMERON
IPC: C23C14/18
Filed: 2006-02-09
Abstract: Disclosed is a method of sealing an ampoule made of polyethylene or polypropylene, comprising forming the ampoule by Blow-Fill-Seal, and applying to an outer surface of the ampoule a coating comprising a metal, a metal compound, or tetrahedral amorphous carbon. Also disclosed is an ampoule made of polyethylene or polypropylene, comprising a coating of a metal, a metal compound, or tetrahedral amorphous carbon, wherein the coating has a depth of up to 20 micrometers.
Patent NZ-562594-A (NZ)
Title: Method and bioreactor for producing synfuel from carbonaceous material
Inventor: KOHR WILLIAM J
IPC: C02F3/34
Filed: 2006-03-29
Abstract: A method for producing liquid and gaseous synfuel from carbonaceous material, the method comprising the steps of: forming a solid state stacked particle bioreactor with a plurality of particles comprising biodegradable carbonaceous material, the solid state bioreactor having an inter-particle void volume, and the solid state stacked particle bioreactor including a drainage system configured to continuously drain liquid from the stacked particle bioreactor so that the stacked particles are not submerged in a liquid phase; inoculating the solid state stacked particle bioreactor with a culture comprising one or more aerobic and/or facultative anaerobic microorganisms capable of fermenting the carbonaceous material;fermenting the carbonaceous material in the solid state stacked particle bioreactor to produce alcohol;converting the environment within the solid state stacked particle bioreactor from an aerobic environment to an anaerobic environment;inoculating the solid state stacked particle bioreactor with a culture comprising one or more anaerobic microorganisms;anaerobically bioconverting fermentation products in the stacked particle 20 bioreactor to gaseous synfuel; and collecting alcohol and gaseous synfuel from the solid state stacked particle bioreactor.
Patent NZ-569244-A (NZ)
Title: The use of bacillus PB6 for the prophylaxis or treatment of gastrointestinal and immuno-related diseases
Inventor: SAS BENEDIKT
IPC: A61K35/742
Filed: 2006-11-29
Abstract: Provided is the use of an isolated bacterial strain having at least 95% homology to the 16S rRNA sequence of SEQ ID NO. 1 for the manufacture of a medicament formulated for the prophylaxis of a bowel condition. The ATCC deposit of an exemplary strain is PTA-6737. The bowel condition can be inflammatory bowel disease, antibiotic associated diarrhea or diarrhea caused by Clostridium difficile.
Patent NZ-578648-A (NZ)
Title: Liquid sulfonylurea herbicide formulations
Inventor: REAP JAMES J
IPC: A01N25/02
Filed: 2008-02-28
Abstract: Disclosed is a single liquid-phase herbicide composition comprising by weight a) 0.1 to 30 percent of one or more sulfonylurea herbicides; b) 0 to 40 percent of one or more biologically active agents other than sulfonylurea herbicides; c) 0 to 30 percent of one or more herbicide safeners; d) 10 to 99.9 percent of one or more polyalkoxylated triglycerides wherein no more than about 50% by weight of the fatty acid-derived moieties in the polyalkoxylated triglycerides are derived from hydroxy fatty acids; e) 0 to 89.9 percent of one or more fatty acid esters of C1-C4 alkanols; and f) 0 to 70 percent of one or more additional formulating ingredients.
Patent NZ-582295-A (NZ)
Title: Yeast autolysates
Inventor: NOORDAM BERTUS
IPC: A23L27/00
Filed: 2008-07-10
Abstract: Disclosed is a yeast autolysate, having a dry solids ratio of between 50 percent and 95 percent and comprising at least 0.75 percent w/w 5'-GMP based on sodium chloride free dry matter of the yeast autolysate and whereby the "dry solids ratio" is defined as the ratio between solubilised solids and total solids of the yeast autolysate. Also disclosed is a process for preparing the yeast autolysate comprising subjecting yeast to autolysis at pH 4-7 and at a temperature in the range of 30-70 degrees C in the presence of an endogenous protease of the yeast; and further enzymatic treatment to produce 5'-ribonucleotides and concentrating the complete reaction mixture to yield the yeast autolysate.
Patent NZ-582823-A (NZ)
Title: Composition of tumour-associated peptides and related anti-cancer vaccine
Inventor: SINGH HARPREET
IPC: A61K39/00
Filed: 2008-07-25
Abstract: Disclosed is a pharmaceutical composition comprising at least two peptides that have the ability to bind a molecule of the human histocompatibility complex (MHC) class I or class II and are between 8 and 100 amino acids long. The pharmaceutical composition is used in the manufacture of a medicament for treating or preventing cancer.