baber/WOPTO huggingface dataset:
Patent AU-2021331023-A1 (AU)
Title: Novel compound, alpha-synuclein aggregate binder, and use thereof
Inventor: HIGUCHI MAKOTO
IPC: C07D417/06
Filed: 2021-08-24
Abstract: The present invention relates to a compound represented by formula (I) or (II), a pharmaceutically acceptable salt of the compound, or a solvate of the compound or the pharmaceutically acceptable salt.
Patent AU-2021333655-A1 (AU)
Title: Methods and compositions for genetic modulation of tumor microenvironments
Inventor: BISSONNETTE REID P
IPC: A61K31/4709
Filed: 2021-08-24
Abstract: Provided herein is a therapy comprising an HDAC inhibitor (HDACi), and/or a PD-L1 and/or a PD-1 inhibitor, and/or a CTLA-4 inhibitor. The combination therapy provided herein can be a kit or the composition or a pharmaceutical composition. Also, provided herein is a method of treating cancer using the combination therapy.
Patent AU-2021336099-A1 (AU)
Title: Compositions and methods for providing health benefits in an animal
Inventor: YU PING
IPC: A61P37/08
Filed: 2021-08-10
Abstract: A method of enhancing vaccine efficacy, treating or preventing an allergy, or treating or preventing an autoimmune disease in an animal can comprise administering to the animal a composition comprising colostrum.
Patent AU-2021337213-A1 (AU)
Title: Microorganism and uses thereof
Inventor: ROBINSON SIMON
IPC: A23K50/10
Filed: 2021-08-25
Abstract: The present invention relates to a novel microorganism and particularly, but not exclusively, the use of the microorganism for supporting or improving the health of an animal and/or treating disease in an animal. The novel microorganism, designated
Patent AU-2021341895-A1 (AU)
Title: New pharmaceutical compounds, methods and uses thereof
Inventor: ATAÍDE SARAIVA LUCÍLIA HELENA
IPC: A61P35/00
Filed: 2021-09-10
Abstract: The present disclosure relates to novel compounds according to general Formula I or a pharmaceutically acceptable acid or base addition salts, hydrate, solvate, N-oxide, stereo chemically isomer forms, in particular diastereoisomer, enantiomer or atropisomers, or mixtures thereof, a polymorph or ester thereof. The present disclosure also relates to a pharmaceutical composition comprising a compound or prodrug thereof of Formula I for use in the treatment of conditions influenced by homologous recombination DNA repair pathway and wild-type, mutant and other BRCA1 and/or BRCA2 deficiencies, namely therapy or treatment of cancer.
Patent AU-2021381874-A1 (AU)
Title: Roller bearing seal assembly
Inventor: LIEBE TIMOTHY M
IPC: F16C33/80
Filed: 2021-10-05
Abstract: In accordance with one aspect of the present disclosure, a rotor for a railway roller bearing seal assembly is provided. The rotor includes an annular body rotatable about a central axis and including radially inner and outer rings. The annular body includes an intermediate portion connecting the radially inner and outer rings and spacing the radially inner ring in a first direction from a base portion of the annular body. The annular body further includes a pocket formed at least in part by the intermediate portion and a snap-fit portion axially intermediate the base portion and a free end portion of the radially inner ring. The snap-fit portion of the annular body is configured to form a snap-fit connection with a snap-fit member of a slinger that extends into the pocket.
Patent AU-2022200355-A1 (AU)
Title: Target device for use in firearm training
Inventor: BAIRD DAVID
IPC: F41J9/02
Filed: 2022-01-19
Abstract: A target device (1) comprises an electric-powered 4-wheel drive zero-turn base (2). A 
mannequin (3) simulating a human-like torso is mounted on a pivotable shaft (4). A 
paintball rifle firearm (5) is attached to the upper end of the shaft (4) for firing dye-filled 
gel capsules (6). A thermal imaging day/night camera (7) is fixed to the firearm (5).  
Force sensors (8) are positioned on the mannequin (3) at positions simulating the head, 
heart, throat and left and right lung regions of a human. A fused LiDAR depth camera 
(9) is fitted to the base (2). Control of the base (2), the mannequin (3), the firearm (5) 
and cameras (7,9) is by software uploaded to one or more CPUs (10) housed within the 
base (2). All components of the target device (1) are manufactured from, or covered 
by a layer of, any suitable ballistic-resistant steel with the exposed surfaces of the force 
sensors (8) and the lens of the cameras (7,9) being covered by bullet-proof glass.
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Patent AU-2022201404-A1 (AU)
Title: Methods for treating or preventing ophthalmological conditions
Inventor: PATEL SAMIR
IPC: A61P27/02
Filed: 2022-03-01
Abstract: The present invention relates to methods for treating and preventing ophthalmological disease 
and disorders, comprising administering Antagonist A or another pharmaceutically acceptable 
salt thereof, optionally in combination with another treatment, to a subject in need thereof. The 
present invention also relates to methods for treating and preventing ophthalmological disease 
and disorders, comprising administering an anti-C5 agent (e.g., ARC1905), optionally in 
combination with another treatment, to a subject in need thereof.
Patent AU-2022201525-A1 (AU)
Title: Surgical staple implant kit
Inventor: CHAMBERS CASEY
IPC: A61B17/068
Filed: 2022-03-04
Abstract: A staple sizer for determining sizes of surgical staples during surgery, comprising: a disc-shaped 
member comprising a plurality of sections corresponding to different sizes of surgical staples; a 
pair of parallel protrusions disposed within each of the plurality of sections and extending away 
from the center of the staple sizer; and a pair of holes disposed adjacently to each pair of parallel 
protrusions.
Patent AU-2022201588-A1 (AU)
Title: Novel Phytophthora resistant Catharanthus roseus plant
Inventor: HERSHBERGER AMANDA
IPC: A01H5/02
Filed: 2022-03-08
Abstract: DCC - 8/03/2022 
ABSTRACT 
The present invention relates to plants of the genus Catharanthus containing a broad spectrum genetic 
resistance to Phytophthora. In particular, the present invention relates to a Catharanthus roseus plant 
5 containing a broad spectrum genetic resistance to P. nicotianae.
Patent AU-2022204465-A1 (AU)
Title: Media capture lock affordance for graphical user interface
Inventor: DAVYDOV ANTON M
IPC: G06F3/0488
Filed: 2022-06-24
Abstract: The disclosed embodiments are directed to a media capture lock affordance for a graphical 
user interface displayed by a media capture device. The media capture lock affordance 
allows a user to lock and unlock a capture state of the media capture device using a simple 
and intuitive touch gesture that can be applied by the user's finger (e.g., the user's thumb) 
while holding the media capture device in one hand.
Patent AU-2022209116-A1 (AU)
Title: System and method for treatment of human stones
Inventor: LAMRINI SAMIR
IPC: A61B18/26
Filed: 2022-01-14
Abstract: A laser lithotripsy system includes a thulium-based laser that, upon activation, selectively produces a continuous wave of laser light with a first wavelength or uniformly spaced, intermittent pulses of laser light with the first wavelength. The system further includes a second laser that, upon activation, produces laser light with a second wavelength, which is shorter than the first wavelength. The system includes an optical detector positioned to receive light emitted by a target in response to the target being impacted by the light produced by the second laser, and a controller communicatively coupled to both the optical detector and the first laser such that the controller selectively activates and deactivates the first laser based on one or more measured characteristics of the light emitted by the target and received by the optical detector.
Patent AU-2022218640-A1 (AU)
Title: Implantable reporting processor for an alert implant
Inventor: BAILEY STEPHEN M
IPC: A61B5/00
Filed: 2022-08-22
Abstract: The present disclosure provides alert implants that comprise a medical device 
and an implantable reporting processor (IRP), where one example of such a medical 
device includes a component for a total knee arthroplasty (TKA) such as a tibial 
extension, a femoral component for hip replacements, a breast implant, a distal rod for 
arm or leg breakage repair, a scoliosis rod, a dynamic hip screw, a spinal interbody 
spacer, and tooling and methods that may be used to form the alert implant, and uses 
of such alert implants in the health maintenance of patients who receive the implant.  
204
Patent AU-2022224178-A1 (AU)
Title: Thermostat device
Inventor: NISHIMURA TETSUYA
IPC: F01P7/16
Filed: 2022-02-16
Abstract: Provided is a thermostat device with which a flow rate of a cooling liquid from a bypass passage can be adequately ensured, and which has excellent temperature sensitivity corresponding to the temperature of the cooling liquid from an engine.　A thermo-operating unit 2 is provided with a control valve 2c for controlling an introduction quantity of cooling liquid from a first inflow port 5a via a radiator, in accordance with the temperature of the cooling liquid from a second inflow port 4b via a bypass passage. Within the housing 3 are provided a plurality of guide bodies 4g which are formed extending from the second inflow port 4b side toward a thermoelement 2a, are arranged intermittently around the thermoelement 2a, and which support the thermoelement 2a in such a way as to be capable of moving in an axial direction, and cooling liquid rectifying claws 4h arranged spaced apart from the thermoelement 2a between the guide bodies 4g, wherein a detour passage 4i for the cooling liquid, directed from the second inflow port 4b side toward an outflow port 4c, is formed by forming gap portions between the guide bodies 4g and the cooling liquid rectifying claws 4h.
Patent AU-2022228272-A1 (AU)
Title: Engine and vehicle with engine
Inventor: WANG QIANG
IPC: F02B31/04
Filed: 2022-01-21
Abstract: An engine, comprising a cylinder block (10), a cylinder head (20) and a piston (30), wherein the cylinder head (20) is fixedly connected to the cylinder block (10); the piston (30) is movably connected to the cylinder block (10); a combustion chamber (101) is defined by the cylinder block (10), the cylinder head (20) and the piston (30); the cylinder head (20) is provided with a gas intake valve hole (201) and a gas exhaust valve hole (202); a gas intake valve (41) is arranged at the gas intake valve hole (201); a gas exhaust valve (42) is arranged at the gas exhaust valve hole (202); the edge of the gas intake valve hole (201) that is away from the gas exhaust valve hole (202) is provided with a raised barrier protrusion (21); and an included angle between lines connecting two ends of the barrier protrusion (21) to the center of the gas intake valve hole (201) is greater than 120 degrees and less than or equal to 180 degrees. In practical applications, the arrangement of the barrier protrusion can improve an intra-cylinder tumble effect and improve the thermal efficiency of the engine.
Patent AU-2022242000-A1 (AU)
Title: Methods of treating cancer in immunosuppressed or immunocompromised patients by administering a pd-1 inhibitor
Inventor: DESAI JIGAR
IPC: A61K39/00
Filed: 2022-03-22
Abstract: The present disclosure provides methods for treating or inhibiting the growth of a tumor, including selecting a patient with cancer, wherein the patient is immunosuppressed or immunocompromised, and administering to the patient a therapeutically effective amount of a programmed death 1 (PD-1) inhibitor (e.g., an anti-PD-1 antibody, such as cemiplimab or a bioequivalent thereof). In certain embodiments, the cancer is skin cancer, such as cutaneous squamous cell carcinoma.
Patent AU-2022247379-A1 (AU)
Title: An apparatus for working a wet coating on a surface and a method of the same
Inventor: SOLER ELODIE
IPC: E04F21/08
Filed: 2022-03-25
Abstract: An apparatus for working a wet coating, such as render material, applied to a surface, the apparatus comprising: an actuator arranged to move an arm across a surface having a wet coating applied thereon; a controller configured to move the arm across the surface along a tool path; and a tool head mounted to the arm, the tool head comprising a compliance module and a tool mounted to the compliance module such that the tool is movable in a stroke direction towards the surface relative to the arm. The compliance module comprises a biasing module arranged to urge the tool in the stroke direction to maintain contact between the tool and the wet coating such that the tool works the wet coating as the arm moves across the surface.
Patent AU-2022258110-A1 (AU)
Title: Method for interconnecting floor drains
Inventor: FRANK KEITH
IPC: E03F5/04
Filed: 2022-04-04
Abstract: A method for interconnecting floor drains includes attaching a first elbow fitting to an existing floor drain through an existing floor. A second elbow fitting is attached to a new floor drain that is to extend through a new floor overlying the existing floor. An extension pipe extends between the spaced first and second elbow fittings to create a fluid pathway between the new floor drain and the existing floor drain.
Patent AU-2022259816-A1 (AU)
Title: Drug eluting ocular implant
Inventor: HAFFNER DAVID
IPC: A61F2/00
Filed: 2022-10-27
Abstract: C:\Users\ljr\AppData\Roa.ing\iManagc\Work\Recent\35544550AU Drugcutnocular mpIant\Disional spc pags (SOI andcla, is) forfurtherdiv(23642928.1).doex-27/10/2022 
Abstract 
A drug delivery ocular implant comprising: an outer shell shaped to define an interior 
space, the outer shell having a sidewall, one closed distal end, and one open proximal end; 
a drug contained within the interior space; a membrane proximate the open proximal end, 
the membrane being permeable or semi-permeable to the drug; a cap dimensioned to fit 
within or over the one open end; and an anchor on the closed distal end; wherein the cap 
secures the membrane to the outer shell while providing at least one opening to allow the 
drug to elute from the implant through the membrane to an anterior chamber of an eye, 
wherein the at least one opening of the cap and the membrane together control a rate of 
elution of the drug from the implant through the membrane and the at least one opening of 
the cap; wherein the cap comprises at least one region that is compressible such that the 
cap is securely sealed to the outer shell.  
91
Patent AU-2022261117-A1 (AU)
Title: Treatment of cancer with a raf inhibitor
Inventor: FRANOVIC ALEKSANDRA
IPC: A61K31/397
Filed: 2022-04-22
Abstract: Provided herein are compositions and methods for the treatment of a cancer. Said compositions comprise a RAF inhibitor. Some embodiments comprise combination therapy featuring the RAF inhibitor with at least one oncology therapeutic agent.
Patent AU-2022264037-A1 (AU)
Title: Methods and compositions for treatment of diabetic retinopathy and related conditions
Inventor: SOOCH MINA
IPC: A61K31/20
Filed: 2022-04-29
Abstract: The invention provides methods, compositions, and kits containing a first therapeutic agent that is a substituted 2,3-dimethoxyquinone of Formula I, or a pharmaceutically acceptable salt thereof, for treating patients suffering from diabetic retinopathy, diabetic macular edema, and/or other diabetic retinal disorders and/or other disorders.
Patent AU-2022273722-A1 (AU)
Title: Methods of manufacturing a high molecular weight heparin compound
Inventor: FU LI
IPC: C08B37/00
Filed: 2022-05-12
Abstract: A method of manufacturing a high molecular weight heparin (HMWH) compound is disclosed. The method comprises dissolving heparin to form a heparin solution and fractionating the heparin solution via tangential flow filtration (TFF) using a membrane with a molecular weight cut off (MWCO) between about 8 kDa and about 12 kDa. The TFF yields a retentate comprising fractionated heparin with a weight average molecular weight of about 20 kDa or greater, i.e., a high molecular weight heparin compound. A substantial proportion of heparin chains in the fractionated heparin may have a high molecular weight, e.g., 50% of the heparin chains or greater may have a molecular weight of 20 kDa or greater.
Patent AU-2022279565-A1 (AU)
Title: Density meter
Inventor: PETERS JAN
IPC: G01N9/06
Filed: 2022-05-25
Abstract: The invention relates to a density meter for slurry which is transported through pipes, the density meter comprising: - a housing having, on opposites sides of the housing, two flanged pipe couplings for coupling of a feed pipe and a discharge pipe; - a pipe part housed in the housing and extending between and spaced apart from the two flanged pipe couplings; - a flexible sleeve having on both ends a flange, which flexible sleeve extends through both pipe couplings and the pipe part and wherein the flanges of the flexible sleeve abut against the flange of the respective flanged pipe coupling; and - a sensor arranged to the pipe part and computing means for computing the density of the slurry in the pipe part at least on the basis of the volume of the pipe part and measurements of the sensor; wherein each flange of the flexible sleeve has an inner annular portion of a first thickness and an outer annular portion of a second thickness, wherein the first thickness is smaller than the second thickness; and in that a spacer ring is provided around each flange of the flexible sleeve and wherein the spacer ring abuts against the flange of the respective flanged pipe coupling, which spacer ring has a thickness of the first thickness or less.
Patent AU-2022287537-A1 (AU)
Title: Object identification and collection system and method
Inventor: FREI BRENT RONALD
IPC: G05D1/00
Filed: 2022-12-12
Abstract: OF THE DISCLOSURE 
An object identification and collection method is disclosed. The method includes 
employing an image-collection vehicle to capture first images of a target geographical area, 
identifying one or more objects in the first images, and guiding an object-collection system over 
the target geographical area toward the one or more identified objects. The method further 
includes determining object information for each of the identified objects and guiding the 
object-collection system based on the object information. The method may further include 
capturing second images of the ground relative to the object-collection system as the object
collection system is guided toward the one or more identified objects, identifying a target object 
in the second images, and instructing the object-collection system to pick up the target object.
Patent AU-2022287551-A1 (AU)
Title: Mixed binding domains
Inventor: DE KRUIF CORNELIS ADRIAAN
IPC: C07K16/00
Filed: 2022-12-12
Abstract: A binding domain or a multimer or a variant thereof which comprises a variable region 
encoded by a nucleic acid based on, derived or obtained from an animal phylogenetically distal from a 
5 human, which variable region is paired with a human variable region.
Patent AU-2022295186-A1 (AU)
Title: Wear component securement
Inventor: RUVANG JOHN A
IPC: E02F9/28
Filed: 2022-06-15
Abstract: A wear component securement system can include a housing securable against rotation relative to a wear component, a pin rotatable in a passage of the housing about an axis of rotation, the pin being configured to displace along the axis of rotation in response to rotation of the pin in the passage, and a resilient member that resists rotation of the pin away from a locked position relative to the housing. A method can include installing a housing, a pin received in the housing, and a resilient member that resists rotation of the pin, the installing including preventing rotation of the housing relative to the wear component, and rotating the pin to a locked position, thereby aligning at least one bearing surface of the pin with at least one bearing surface of the wear component.
Patent AU-2023202199-A1 (AU)
Title: No-back brake for a flight control actuation system and method
Inventor: MEHRTENS JAMES A
IPC: B64C13/24
Filed: 2023-04-11
Abstract: A no-back brake (100) includes a torque tube (126) and a brake (102). The brake is 
configured to be axially displaced in response to a force to prevent the torque tube (126) from 
rotating. The brake includes a rotor that is concentric with the torque tube and that is fixed to the 
torque tube so that the rotor rotates with the torque tube. The brake includes a stator that is 
concentrically mounted on the torque tube so that the torque tube is rotatable relative to the 
stator. The brake includes a friction device located between the rotor and the stator. The friction 
device is configured to form a frictional coupling between the rotor and the stator that opposes 
relative rotational motion between the rotor and the stator when the brake is axially displaced.  
The frictional device includes a composite material.
2/12 
304 
306 
202 310 
FIG. 2 50b 
206 20200 
218 
214 100 204 
210 208 
216 212 
254 
31O FIG. 3
Patent AU-2024200190-A1 (AU)
Title: Presenting avatars in three-dimensional environments
Inventor: BUTCHER GARY IAN
IPC: G06F3/01
Filed: 2024-01-11
Abstract: OF THE DISCLOSURE 
In some embodiments, a computer system receives data representing a pose of 
at least a first portion of a user and causes presentation of an avatar that includes a respective 
avatar feature corresponding to the first portion of the user and presented having a variable 
display characteristic that is indicative of a certainty of the pose of the first portion of the 
user. In some embodiments, a computer system receives data indicating current activity of 
one or more users is activity of a first type and, in response, updates a representation of a user 
having a first appearance based on a first appearance template. The system receives second 
data indicating current activity of the one or more users and, in response, updates the 
appearance of the representation of the first user based on the current activity of the one or 
more users using the first or a second appearance template.
Patent AU-2024200192-A1 (AU)
Title: Deployment of downhole sensing device(s)
Inventor: STEWART GORDON
IPC: E21B47/00
Filed: 2024-01-11
Abstract: A downhole sensing device deployment control apparatus 10 includes means to 
control speed of the sensing device progressing within a borehole associated with 
a drilling operation. A mechanical, electrically powered and/or hydro-dynamic 
drag/damping means/device 12 can be provided as part of the control apparatus 
to control speed of deployment down the borehole. The drag device 12 can have 
a plurality of wheels or rollers to contact an internal bore of an inner pipe of a drill 
string. Rotation control means 24, 26 can be provided to control an amount of 
rotation and/or direction of rotation of the wheels or rollers relative to travel of the 
sensing device within the borehole. Valving 60 can be provided. A two stage 
(dual) flow/pressure control valve 100 can be provided. A sensing device release 
216 and downhole position latch 202 can be provided. The sensing device can be 
pumped into the borehole, such as by compressed air.  
20510782_1 (GHMatters) P40834AU02
Patent WO-2004111353-A1 (WO)
Title: Device and method for dislodging and recovering dredging material of varying nature
Inventor: CLYMANS ETIENNE
IPC: E02F3/92
Filed: 2004-06-10
Abstract: Device for dislodging and recovering dredging material of varying nature, comprising a bearing housing (25), a drive shaft (11) mounted therein for rotatingly driving with a determined torque a cutter head (10, 10’) with a support ring (15, 15’), which cutter head is mountable on the drive shaft via a hub (9), and a suction pipe (13) which can be connected to a suction mouth (14, 14’) which is surrounded by a fixed cutter shield (21, 21’) which fills the space between the rotating support ring on the one side and the suction mouth and the bearing housing on the other, wherein a number of cutter heads with a different support ring diameter can be mounted on the drive shaft, wherein the support ring diameter is determined by the torque and the nature of the dredging material to be recovered.