baber/WOPTO huggingface dataset:
Patent DE-69230918-D1 (DE)
Inventor: COHEN J
IPC: G01N33/574
Filed: 1992-11-24
Granted: 2000-05-18
Abstract: The present invention relates to an improved method and kit for the detection of antibodies directed against the human immunodeficiency virus (HIV) in whole blood obtained from individuals who are HIV-seronegative as determined by conventional assay techniques. Whole blood is isolated from these individuals and cultured directly with mitogen to stimulate the proliferation of B-lymphocytes producing immunoglobulin specific for HIV. This method provides a rapid, simple, and inexpensive means for screening large numbers of blood samples for HIV infection while minimizing exposure of the technician to infectious blood components.
Patent DE-69233189-D1 (DE)
Inventor: STRUPCZEWSKI JOSEPH T
IPC: A61K31/535
Filed: 1992-11-04
Granted: 2003-10-09
Abstract: Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.
Patent DE-69233796-D1 (DE)
Inventor: STRUPCZEWSKI JOSEPH T
IPC: C07D403/14
Filed: 1992-11-04
Granted: 2010-12-02
Abstract: Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.
Patent DE-69300546-D1 (DE)
Inventor: BUENDIA JEAN
IPC: C07J3/00
Filed: 1993-06-17
Granted: 1995-11-02
Abstract: The subject of the invention is a process for the preparation of the compound of formula (I): <IMAGE> characterised in that the corresponding 9 alpha -OH compound is treated with chlorosulphonic acid in an organic solvent.
Patent DE-69309891-D1 (DE)
Inventor: BIANCHI EMILIO
IPC: F04D29/36
Filed: 1993-10-13
Granted: 1997-05-22
Abstract: PCT No. PCT/EP93/02815 Sec. 371 Date Jun. 10, 1994 Sec. 102(e) Date Jun. 10, 1994 PCT Filed Oct. 13, 1993 PCT Pub. No. WO94/09277 PCT Pub. Date Apr. 28, 1994.A device for connecting blades (7) to a hub (5) in a propeller of either a fan or an aircraft has a variable fitting in at least a moving position. An L-shaped element (1) connects each blade (7) to the hub (5) so that an attachment of the blade (7) to the hub (5) has a longitudinal axis eccentric with respect to a longitudinal axis of the hub (5). The L-shaped element (1) has a first long leg aligned parallel with a longitudinal axis of the blade (7). The L-shaped element (1) also has a short leg perpendicular to a flat plane of the blade (7) and parallel to a rotational axis of the hub (5). A screw (4) fastens the second short leg of the L-shaped element (1) to the hub (5). This screw (4) is aligned parallel to the flat plane of the blade (7) but has a longitudinal axis spaced from the flat plane of the blade (7). A circular crown (6) presses the L-shaped element (1) to the hub (5) while a hole (3) retains the screw (4) whereby the hole (3) is eccentric with respect to the crown (6). The eccentricity (e) of the hole (3) and the screw (4) with respect to a longitudinal axis of the crown (6) is not less than 10% of an exterior diameter of the crown (6).
Patent DE-69309941-D1 (DE)
Inventor: FITZJOHN STEVEN LEICESTER
IPC: A01N43/54
Filed: 1993-09-10
Granted: 1997-05-22
Abstract: The invention provides novel compounds of formula (I) having nematicidal, insecticidal, acaricidal and fungicidal properties, compositions comprising them and processes and intermediates for their preparation:    <IMAGE>  (I)  wherein R1 is -S(O)nCH2CH2CH=CF2; n is selected from 0, 1 and 2; R2, R3, and R4 are independently selected from hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, alkylcycloalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted aryloxy, optionally substituted arylalkoxy, alkoxy, alkenyloxy, alkynyloxy, hydroxyalkyl, alkoxyalkyl, alkylthio, alkenylthio, alkynylthio, haloalkyl, haloalkenyl, haloalkynyl, haloalkoxy, haloalkenyloxy, haloalkynyloxy, haloalkylthio, haloalkenylthio, haloalkynylthio, halogen, hydroxy, cyano, nitro, -NR5R6, -NR7COR8, -NR9SO2R10, -N(SO2-R11)(SO2-R12), -COR13, -CONR14R15, -COOR16, -OCOR17, -OSO2R18, -SO2NR19R20, -SO2R21, -SOR22, -CSNR23R24, -SiR25R26R27, -OCH2CO2R28, -OCH2CH2CO2R29, -CONR30SO2R31, -SO2Z, or an adjacent pair of R2, R3 and R4 when taken together form a fused 5- or 6-membered carbocyclic or heterocyclic ring; R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, R25, R26, R27, R28, R29, R30 and R31 are independently selected from hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, optionally substituted aryl and optionally substituted arylalkyl; and Z is halogen.
Patent DE-69318179-D1 (DE)
Inventor: ROYALL SVEN
IPC: C08L91/00
Filed: 1993-12-14
Granted: 1998-05-28
Abstract: A refined petroleum wax composition comprises a refined petroleum wax and, as a stabilising agent, tocopherol and/or a derivative thereof. The refined petroleum wax may be a paraffin wax, a microcrystalline wax or a Fischer-Tropsch wax. A method for preparing the refined petroleum wax composition comprises adding to a refined petroleum wax tocopherol and/or a derivative thereof.
Patent DE-69318836-D1 (DE)
Inventor: DE CLERCQ ERIK
IPC: A61K31/505
Filed: 1993-06-18
Granted: 1998-07-02
Abstract: 1,5-Anhydrohexitol nucleoside analogues represented by the general formula I:   <IMAGE>   wherein the hexitol has the D-configuration and the carbon atom on which the base moiety and the X substituent stand both have the (S)-configuration and further wherein: B is a heterocyclic ring selected from the group consisting of pyrimidine and purine bases; and X is hydrogen, azido, F, Cl, Br, I, amino, -NHR2, -N(R2)2, -OR2, -SR2, or CN; wherein R1 and R2 are the same or different and are selected from the group consisting of hydrogen, substituted or unsubstituted C1-C20alkyl, substituted or unsubstituted C1-C20alkenyl, aroyl, C1-C20alkanoyl, and phosphoryl. These nucleoside analogues are useful as antiviral agents against herpes simplex virus, vaccina virus, or varicella zoster virus. The definition of the X group should include -N(R2)2 instead of -N(N2)2.
Patent DE-69321473-D1 (DE)
Title: Amylin muteine
Inventor: ANDREWS GLENN
IPC: G01N33/60
Filed: 1993-05-12
Granted: 1998-11-12
Abstract: This invention relates to muteins of amylin and derivatives thereof having insulin action suppressing activity as well as the pharmaceutically-acceptable salts thereof. The muteins and derivatives of this invention are useful for suppressing insulin action in muscle or muscle cells and for suppressing insulin action in a mammal in need thereof. Thus, this invention further relates to a method of suppressing insulin action in a mammal in need thereof and methods for suppressing insulin action in muscle or muscle cells as well as pharmaceutical compositions comprising the above described muteins, derivatives or salts. This invention also relates to a method for assaying the ability of a compound to inhibit the suppression of insulin action in muscle or muscle cells caused by amylin.
Patent DE-69324250-D1 (DE)
Inventor: LARSEN THOMAS
IPC: A01N53/02
Filed: 1993-04-29
Granted: 1999-05-06
Abstract: The invention described here concerns the unique utility of fatty acids and their derivatives to act as fruit thinning agents. Proper use of the methods and compositions will result in the advantageous thinning of fruit which can improve the quality of the harvested fruit and result in more consistent crops from one year to the next.
Patent DE-69325269-D1 (DE)
Inventor: DUNMIRE CHARLES
IPC: F16K15/03
Filed: 1993-03-05
Granted: 1999-07-15
Abstract: A backflow preventor which permits adjustment of the outflow direction is provided. A conduit provides fluid communication between the two valves of the backflow preventor. The conduit can be separated, e.g., by cutting along a groove, leaving annular flat regions. The annular flats are configured to engage with a coupler to provide leak-free connection between the separated portions of the conduit. The separated portions of the conduit can be rotated to adjust the outflow direction. Preferably, an infinite number of outflow directions are possible, all of which lie in a plane parallel to the inflow direction.
Patent DE-69332148-D1 (DE)
Inventor: PIGNARD ANNIE
IPC: C12N15/53
Filed: 1993-12-07
Granted: 2002-08-29
Abstract: The invention relates to the novel use of a sequence coding for a protein capable of degrading oxalic acid to select plant cells which have integrated a gene of interest, and a novel process for selecting, on oxalic acid, cells, calluses or plants transformed by this recombinant DNA.
Patent DE-69400631-D1 (DE)
Inventor: REMINGTON JACK S
IPC: A61K31/4353
Filed: 1994-04-29
Granted: 1996-11-07
Abstract: A method of reducing the severity of toxoplasmosis resulring from infection of a patient with Toxoplasma gondii by administering to a patient in need of such treatment, either after infection or before exposure to infection, a therapeutically effective amount of a compound that is a spiropiperidyl derivative of rifamycin S, wherein the derivative comprises an imidazole ring that includes carbons at positions 3 and 4 of the rifamycin ring, the carbon at position 2 of the imidazole ring also being a ring carbon at position 4 of a piperidine ring system, thereby forming a spiropiperidyl ring system, the spiropiperidyl ring system optionally comprising a lower hydrocarbon substituent on the nitrogen of the piperidine.
Patent DE-69402731-D1 (DE)
Inventor: JENSMA KLAAS
IPC: A61B18/00
Filed: 1994-01-27
Granted: 1997-05-28
Abstract: In methods and apparatus for cooling surfaces, a pressurized liquid refrigerant is dispensed through a shaped member composed of an open celled foam. The method is particularly useful for localized freezing of a wart or other growth prior to its removal from skin of a human being or another animal. <IMAGE>
Patent DE-69403393-D1 (DE)
Inventor: RAUDASKOSKI VESA
IPC: B65H18/20
Filed: 1994-06-29
Granted: 1997-07-03
Abstract: The invention concerns a method in drum winding of a web (P), wherein the roll (13) that is being formed is supported on winding drums (11,12), as well as a drum winder (10). At least a part of the area that surrounds the roll (13) that is being formed is subjected to a pressure lower than the pressure that prevails in the gap formed by the roll (13) that is being formed and the winding drums (11,12), whereby a floating effect is produced on the roll (13) that is being formed. The drum winder (10) is preferably placed in a vacuum chamber (30). <IMAGE>
Patent DE-69412248-D1 (DE)
Inventor: HENRY PATRICK
IPC: A61B17/58
Filed: 1994-04-18
Granted: 1998-09-10
Abstract: PCT No. PCT/FR94/00435 Sec. 371 Date Oct. 19, 1995 Sec. 102(e) Date Oct. 19, 1995 PCT Filed Apr. 18, 1994 PCT Pub. No. WO94/23660 PCT Pub. Date Oct. 27, 1994An implant for an ostheosynthesis device, in particular for the spine, comprises an anchoring portion (11) for anchoring to bone and a body in which a channel (13) is formed suitable for receiving a rod (T), the channel opening out sideways in the body, a hollow element (20) suitable for surrounding the body (12) and possessing two notches suitable for receiving the rod on either side of the body (12), and a screw (30) for fixing the hollow element on the body. According to the invention: the hollow element is a cover (20) fitting over the body with a rounded top portion (21b) in which an opening (25) is formed, the body (12) includes a tapped hole (14) facing said opening, and the head (31) of a screw (30) bears against the top (21b, 25a) of the cover, its threaded portion (32) being screwed in the tapped hole through said opening.
Patent DE-69419377-D1 (DE)
Inventor: LABEEUW BERNARD
IPC: A61P25/00
Filed: 1994-10-10
Granted: 1999-08-12
Abstract: The subject of the invention is substituted 1-naphthylpyrazole-3-carboxamides of formula I: <IMAGE>   Application: treatment of neuropsychiatric disorders, in particular those which are associated with dysfunctioning of the dopaminergic systems.
Patent DE-69422722-D1 (DE)
Inventor: ALLEN I
IPC: B32B27/08
Filed: 1994-08-16
Granted: 2000-02-24
Abstract: An oxygen and moisture impermeable multilayer barrier film is provided including a barrier layer comprising a homopolymer of vinylidene chloride or a copolymer of vinylidene chloride and vinyl chloride or methyl methacrylate. The barrier layer is coextruded with or laminated to at least one heat sealable skin layer comprising a thermoplastic polyurethane, a substantially linear copolymer of ethylene and an  alpha -olefin, or a homogeneously-branched linear olefin resin to form the barrier film. The multilayer film may be used for reusable ostomy bags, for systems for the transdermal delivery of drugs, and for heat sealable bags used in packaging.
Patent DE-69426129-D1 (DE)
Inventor: CYPHER SCIENCE LIMITED CARDIFF
IPC: C12Q1/6816
Filed: 1994-07-12
Granted: 2000-11-16
Abstract: PCT No. PCT/GB94/01506 Sec. 371 Date Mar. 29, 1996 Sec. 102(e) Date Mar. 29, 1996 PCT Filed Jul. 12, 1994 PCT Pub. No. WO95/02702 PCT Pub. Date Jan. 26, 1995A method of marking a solid article or item comprises applying thereto beads having nucleic acids attached thereto. A method of monitoring an interaction between any material, article or item and a person or animal comprises providing a device capable of producing an aerosol containing a nucleic acid label and means to activate the aerosol on interference by a person or animal with the material, article or item. Methods of marking a material comprise adding to the material a plurality of beads having attached thereto a plurality of nucleic acid molecules. At least two distinct primer sequences are associated with different nucleic acid molecules.
Patent DE-69428644-D1 (DE)
Inventor: SU KAI C
IPC: B29C33/00
Filed: 1994-07-12
Granted: 2001-11-22
Abstract: A lens mold includes first (1) and second mold (2) members respectively having a concave (3) surface and a convex surface (4) for defining therebetween a lens cavity. One of the first and second mold members is configured to mechanically engage a ring of excess lens material upon polymerization of the lens material. Alternately, one of the first and second mold members includes a material formed along the periphery of a lens cavity (5) which causes the ring of excess lens material thereto. Furthermore, one of the first and second mold members is formed of a relatively transparent plastic material and includes an outer surface having an optical finish to permit optical inspection of a lens located on one of the concave and convex surfaces. Alternately, one of the first and second mold members is formed of a relatively opaque plastic material and includes an inner surface having an optical finish to permit optical inspection of a lens located on one of the concave and convex surfaces. <IMAGE>
Patent DE-69429699-D1 (DE)
Inventor: DEMARS YVES
IPC: C03B23/24
Filed: 1994-09-21
Granted: 2002-03-14
Abstract: The invention relates to a method for producing a vacuum within insulating glazing made up of two sheets of glass (2, 3) separated by studs (4). According to the invention, one of the sheets of glass has a hole (12) which is plugged by a melted ball (8) once the vacuum has been produced. The invention also relates to insulating glazing in which the sheets of glass are separated by studs (4) and joined round their periphery by means of a sealing joint. <IMAGE>
Patent DE-69431348-D1 (DE)
Inventor: BRUMFIELD L
IPC: A61B17/70
Filed: 1994-01-04
Granted: 2002-10-17
Abstract: A spinal implant system for correcting spinal deformities and abnormalities includes an elongated spinal rod configured to be implanted adjacent the spinal column and spanning across several vertebral levels. A number of fixation elements, such as spinal hooks, are provided for engaging vertebrae at a number of vertebral levels. At least some of the fixation elements includes an elongated stem projecting from a vertebra engaging portion. The stems of each of the fixation elements are connected to the spinal rod by way of a rod connector having a one-piece body defining a rod channel adapted to receive the spinal rod therethrough, a stem bore adapted to receive a stem therethrough, and a threaded bore. The stem bore and rod channel intersect to permit contact between the rod and the stem of a fixation element. The threaded bore intersects either the rod channel or the stem bore so that a set screw threaded into the threaded bore bears against the spinal rod or fixation element stem. As the set screw is tightened in the bore, the spinal rod and stem are clamped together to form a rigid construct. The rod channel includes a channel opening to permit top-loading of the rod connector. The fixation element stem may include external threads to receive a threaded fastener for temporarily threading onto the stem when the implant construct is at an initial posterior level above the spine. As the fastener is threaded onto the stem of each fixation element, the instrumentation is drawn down to a lower final level adjacent the vertebrae.
Patent DE-69431907-D1 (DE)
Inventor: HOEKSTRA JELLE
IPC: H04L12/413
Filed: 1994-08-15
Granted: 2003-01-30
Abstract: PCT No. PCT/IB94/00250 Sec. 371 Date Apr. 17, 1995 Sec. 102(e) Date Apr. 17, 1995 PCT Filed Aug. 15, 1995 PCT Pub. No. WO95/05636 PCT Pub. Date Feb. 23, 1995A multistation single-channel communication bus system accommodating master stations and slave stations, with any master performing arbitration, arbitration outcome detection, and, upon winning the arbitration, formatting a frame having a slave address and slave control signals, and accommodating data byte periods for data transmission from a transmitter station to a receiver station up to a first maximum data byte length. Each period accommodating an acknowledge bit from the receiver station. The transmitter station responding to the absence of the acknowledge bit for a particular data byte by repeating that data byte. The system, for a message whose data byte length would exceed the first maximum, divides the message into partial messages each of an associated frame data byte count below the first maximum, and assigns each partial message to a respective bus frame. The system counts, in a particular frame, data byte periods and received acknowledge bits. The transmitter station, upon attaining the first maximum earlier by the data byte periods than the frame data byte count by the acknowledge bits, signalling a frame failure and ignoring any transfer in the particular frame for undertaking a repeat thereof.
Patent DE-69433386-D1 (DE)
Inventor: MATHUR RAJIV
IPC: A61K8/14
Filed: 1994-10-25
Granted: 2004-01-15
Abstract: Disclosed are lipid vesicles containing a blend of amphiphiles, including propylene glycol stearate, in the lipid bilayers. The vesicles may have either an aqueous or oil-filled central cavity and are particularly useful for delivering dermatological, cosmetic and pharmaceutical formulations. A method of manufacture for these vesicles is also disclosed.
Patent DE-69507774-D1 (DE)
Inventor: ZUBIA HERRERA LUIS
IPC: E05B35/00
Filed: 1995-04-20
Granted: 1999-03-25
Abstract: The locking system includes a blocking and electronic releasing device by means of different codes for each one of the keys, it also being possible to modify the memory of the control circuit by means of an operating key to refuse access to a lost key, also allowing access to other new copies of the key. This electronic blocking is done by means of an independent pin of the locking pistons of the mechanical part of the cylinder, the latter being inside as well as outside the same. The key (4) communicates to the cylinder (1) its code by means of an electric contact (9) through which the energy required for its operation will be supplied to it. The transmission of data of the key to the cylinder is done by the electric contact itself (9). A rotary-type electric motor (10) acts on a blocking pin (6) by means of an eccentric (11) and connecting rod (12.) The control circuit of the cylinder (1) has a memory in which the codes of the keys (4) that have access to the lock appear. The control circuit will launch its reading process of the code of the key to allow or refuse retraction of the blocking pin (6.) <IMAGE>
Patent DE-69522537-D1 (DE)
Inventor: KISIEL PETER
IPC: B60N2/07
Filed: 1995-10-12
Granted: 2001-10-11
Abstract: An adjustable vehicle seat assembly (10) includes a vehicle seat, track assemblies (102, 104) each with a stationary track (106, 108) fixed to a vehicle floor and a translating track (110, 112) slidably interconnected with the stationary track. A horizontal adjustment mechanism (100) provides an occupant of the seat with the ability to position the translating tracks horizontally relative to the stationary tracks. A seat support structure includes forward and rearward seat support arm assemblies (203, 205), for supporting the seat on the translating tracks, and a vertical adjustment mechanism (200) has forward and rearward sector gears (264, 274) coupled with the forward and rearward seat support arm assemblies (203, 205) respectively. Forward and rearward locking members (282, 292) are mounted so as to be selectively engageable with the corresponding sector gear to prevent movement of the sector gear, and seat support arm assembly coupled thereto, when engaged. Forward and rearward camming members (302, 312) are mounted so as to be selectively moved to either engage or disengage the corresponding locking member (282, 292). There are provided a resilient coupling (322) between the camming members, a lever actuated control member (338), an actuating lever (352), and a fore and aft motion transmitting member (242) coupled with the lever actuated control member (338) and the camming members (302, 312) by pin and slot connections, so that upon movement of the lever actuated control member (338) one camming member is moved so as to disengage a corresponding locking member while the other camming member continues to hold the corresponding locking member in the engaged position. <IMAGE>
Patent DE-69523836-D1 (DE)
Inventor: CASSOU ROBERT
IPC: A61D19/00
Filed: 1995-08-24
Granted: 2001-12-20
Abstract: The collector consists of a body or artificial vagina (1) made from a supple foam material, made with an inner conical duct (3) and connected to a container. The body has a flared inlet end to guide the animal's penis as it is introduced, and it is made from a non-toxic foam material. The container can be in the form of a tube (6) connected to a skirt (5) on the end of the body. In a variant of the design the body is connected to the container by a tube with an aperture for removing the 'gel' which forms part of the ejaculate. The collector can be fitted into a dummy on a flexible support and connected via a filter to a vacuum flask.
Patent DE-69524205-D1 (DE)
Inventor: TAKAMURA KOJI
IPC: A61B1/05
Filed: 1995-12-29
Granted: 2002-01-10
Abstract: An endoscopic apparatus comprising a solid-state image pickup device (2) installed in an insert assembly, a signal transmission member (13) for conducting the electric signal into which the solid-state image pickup device (2) photoelectrically converts an optical image, and a flexible tube-like metal member (25) that makes up part of the cover of the insert assembly and/or a flexible tube-like metal member that constitutes part of the universal cord, whereby the signal transmission member (13) is inserted through the insert assembly member and the universal cord, the shield member (21) that covers the signal transmission member (13) is disposed at least in part of the insert assembly and/or part of the universal cord assembly, and the shield member (21) and the metal members (25) are set to be equipotential to each other. <IMAGE>