baber/WOPTO huggingface dataset:
Patent NZ-573048-A (NZ)
Title: Reconstitution device
Inventor: TUCKWELL JONATHAN DAVID
IPC: A61J1/20
Filed: 2007-05-24
Abstract: Disclosed is a reconstitution device which includes a receptacle, a cap, a stopper, a plunger, a locking mechanism and an actuating mechanism. The cap includes a first end, a second end, and an inner bore having a central aperture. The first end of the cap is secured to the receptacle. The stopper is located between the receptacle and the cap. The stopper includes a portion capable of being perforated. The plunger is adapted for being positioned at the second end of the cap and for sliding, within the inner bore of the cap, downward from the second end of the cap towards the first end of the cap. The plunger includes a plunger shaft adapted to perforate the stopper. The locking mechanism is located in the cap and adapted to prevent return motion of the plunger after the plunger has been moved downward. The locking mechanism includes a first aperture, a second aperture, a tongue, and a tab connected to the tongue. The second aperture is located within the tongue and is adapted for the plunger shaft to pass through while the plunger slides downward. The tongue is adapted to be flexed for positioning the tongue within or outside of the first aperture.
Patent NZ-574826-A (NZ)
Title: Decorative laminate incorporating multi-colored photoluminescent material
Inventor: DUMOND ROBERT A
IPC: B32B27/20
Filed: 2007-08-14
Abstract: Disclosed is a decorative laminate (10). The laminate comprises of: a core layer (20) with a resin; a print layer (30) with at least one pattern that is visible under normal light; a first overlay layer (40) impregnated with a resin that includes a first photoluminescent material visible under ultraviolent light; a luminescent layer (50) with at least one pattern that includes at least one second photoluminescent material that is visible under ultraviolet light; and a second overlay layer (60). The core layer, the print layer, the first overlay layer, the luminescent layer and the second overlay layer are stacked in a superimposed relationship. The first photoluminescent material produces a first colour when exposed to ultraviolet light, and where the second photoluminescent material produces a second colour when exposed to ultraviolet light, the first colour being different from the second colour.
Patent NZ-576032-A (NZ)
Title: Antibodies to lymphotoxin-alpha
Inventor: ADAMS CAMELLIA W
IPC: C07K14/525
Filed: 2007-10-11
Abstract: Disclosed are isolated anti-lymphotoxin-alpha (LT-alpha) antibodies, as defined in the specification. The disclosed antibodies comprise the following properties: (i) binding to lymphotoxin-alpha3 trimer (LT-alpha3) and blocking the interaction of LT-alpha3 with tumour necrosis factor receptor-I (TNFRI) and tumour necrosis factor receptor-II (TNFRII); and (ii) blocking the interaction of lymphotoxin-alpha-beta (LT-alpha-beta) with lymphotoxin-beta receptor (LTbeta-R).
Patent NZ-576826-A (NZ)
Title: Production of novel precision customized control release fertilizers
Inventor: PRASAD DURGA YANDAPALLI
IPC: C05G3/90
Filed: 2007-11-06
Abstract: Disclosed is a liquid formulation, said liquid formulation comprising water having dissolved therein: (i) a crop specific customized fertilizer and/or a normal fertilizer; (ii) an agropolymer comprising a carbohydrate and silica matrix, obtained from plant parts of an agricultural crop selected from the group consisting of Oryza sativa, Panicum miliaceum, Setaria italica, Cajanus cajan, Vigna mungo, Vigna radiata, Triticum sp., Ricinus communis, Helianthus annus, Gossypium sp., and Arachis sp, wherein said matrix is substantially devoid of proteins, tannins, and polyphenols, wherein said matrix further comprises metal-binding reactive sites; and (iii) one or more functional transition metal silicates with or without nanostructure, said functional transition metal silicates being selected from the group comprising: a. Cupric silicates having silica to copper ratio in the range of 1:0.34 to 1:5.15; b. Zinc silicates having silica to zinc ratio in the range of 1:2 to 1: 12; c. Silver silicates having silica to silver ratio in the range of 1:15 to 1:19.5; d. Manganese silicates having silica to manganese ratio in the range of 1: 1 to 1:1.9; and e. Zirconium silicates having silica to zirconium ratio in the range of 1:0.77 to 1:2.9.
Patent NZ-584311-A (NZ)
Title: Phenyl and pyridyl substituted tetrazole c-met protein kinase inhibitors
Inventor: LAUFFER DAVID
IPC: C07D417/14
Filed: 2008-09-30
Abstract: Disclosed are tetrazole compounds of formula (I), or pharmaceutically acceptable salts thereof, and methods for their preparation. R5 of the compound of formula (I) is a substituted carbon, and contributes to the compounds' decreased IC50 with respect to hydrogen-substituted analogues. Also disclosed is using compound of formula (I) for treating or lessening the severity of a proliferative disorder in a patient, wherein the proliferative disorder is metastatic cancer, glioblastoma; a gastric carcinoma, atherosclerosis or lung fibrosis or a cancer selected from colon, breast, prostate, brain, liver, pancreatic or lung cancer. Also disclosed is a method of inhibiting c-MET protein kinase activity in a biological sample in vitro comprising contacting said biological sample with a compound of formula (I).
Patent NZ-586140-A (NZ)
Title: Bottom board for a beehive capable of adjusting the size of, or closing the hive entrance
Inventor: FERGUSON STUART LYON
IPC: A01K47/00
Filed: 2010-06-14
Abstract: 586140 Disclosed is a bottom board for a beehive to allow an adjustable hive entrance. The board comprises a support structure, where the top surface of the support structure is suitable for receiving a hive body. The support structure includes a recessed portion that is capable of providing a hive entrance when combined with a hive body; and the size of the hive entrance is dependent on the relative position of the hive body. The recessed portion includes a first recess and a second recess. The bottom board when combined with a hive body, a fully open hive entrance is provided when the hive body position utilises at least the first recess for the hive entrance, and a reduced hive entrance when the hive body position utilises only the second recess for the hive entrance. The hive body may be positioned so that the hive entrance is blocked.
Patent NZ-589252-A (NZ)
Title: Quinazolines useful as inhibitors of voltage-gated sodium channels
Inventor: WILSON DEAN M
IPC: A61K31/498
Filed: 2005-08-31
Abstract: The disclosure relates to quinazoline derivatives of formula (I) that are useful as inhibitors of voltage-gated sodium channels, wherein the variables are as defined in the specification. The disclosure also relates to pharmaceutically acceptable compositions comprising the compounds of formula (I) and methods of using the compositions in the treatment of various disorders.
Patent NZ-590994-A (NZ)
Title: Anti il-7r antibodies treatment of autoimmune and inflammatory disease
Inventor: LEUNG STEWART
IPC: A61K39/395
Filed: 2009-08-07
Abstract: Disclosed is the use of an anti-CD127 antibody in the manufacture of a medicament for use in the treatment of multiple sclerosis in a human subject, wherein said anti-CD127 antibody is an antagonist of IL-7 receptor mediated TH17 expansion and survival.
Patent NZ-596656-A (NZ)
Title: New compositions for treating cmt and related disorders
Inventor: CHUMAKOV ILYA
IPC: A61K31/192
Filed: 2010-05-28
Abstract: 596656 Disclosed herein is a composition comprising baclofen, sorbitol, and a compound selected from pilocarpine, methimazole, mifepristone, naltrexone, rapamycine, flurbiprofen and ketoprofen, or salts, enantiomers, or racemates thereof, and a pharmaceutically acceptable carrier or excipient; and the use of said composition in the treatment of Charcot-Marie-Tooth disease, a toxic neuropathy, oamyotrophic lateral sclerosis.
Patent NZ-600112-A (NZ)
Title: Antibodies directed to angiopoietin-1 and angiopoietin-2 and uses thereof
Inventor: BOONE THOMAS C
IPC: A61K39/395
Filed: 2009-02-20
Abstract: NZ 600112 Disclosed is the use of an isolated monoclonal antibody that specifically binds to at least one of Ang1 and Ang2 ligands of Tie 2 receptor in the manufacture of a medicament for inhibiting undesired angiogenesis in a subject in need thereof. The disclosed antibody comprises a heavy chain (HC) variable domain and a light chain (LC) variable domain, wherein said heavy chain comprises 3 CDRs and said light chain comprises 3 CDRs, wherein the sequences of said CDRs of said antibody are as defined in the complete specification.
Patent NZ-603442-A (NZ)
Title: Treatment of proliferative diseases
Inventor: ANDERSON MARILYN ANNE
IPC: A61K38/16
Filed: 2011-06-23
Abstract: 603442 Discloses methods for preventing or treating proliferative diseases through administering to non-humans a)solanaceous Class II plant defensin, b) a nucleic acid encoding the Solanaceous Class II plant defensin; c) a vector comprising the nucleic acid; d) a host cell comprising the vector; e) an expression product produced by the host cell; or f) a pharmaceutical composition comprising the plant, defensin, the nucleic acid, the vector, the host cell or the expression product, together with a pharmaceutically acceptable carrier, diluent or excipient; also discloses a kit, the use and composition of the above for the treatment or prevention of proliferative diseases (such as tumor).
Patent NZ-603811-A (NZ)
Title: Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases
Inventor: WATKINS JEFFRY D
IPC: A61P35/00
Filed: 2011-07-11
Abstract: Discloses a therapeutic composition, comprising an isolated aminoacyl-tRNA synthetase (AARS) polypeptide of up to 300 amino acids in length that comprises SEQ ID NO: 16 or 14 or an amino acid sequence that is at least 90% identical to SEQ ID NO: 16 or 14, wherein the AARS polypeptide has an extracellular signalling activity and a solubility of at least about 5 mg/mL, and wherein the composition has a purity of at least about 95% on a protein basis and less than about 10 EU endotoxin / mg protein.
Patent NZ-614107-A (NZ)
Title: Process for production of microalgae, cyanobacteria and metabolites thereof
Inventor: DODD JOHN
IPC: C12R1/89
Filed: 2012-01-30
Abstract: Disclosed is a process for the enhanced production of one or more metabolites in microalgae and/or cyanobacteria, said process comprising the steps of: (i) culturing a microalgal or cyanobacterial strain through a production phase; (ii) exposing the microalgal or cyanobacterial culture to a stimulus, wherein the stimulus comprises (a) a decrease in pH to a pH of no more than pH 6, followed by an increase in pH to a pH of no less than pH 7 and (b) an increase in light irradiance to at least 400 micromol/sq m/sec
Patent NZ-616432-A (NZ)
Title: Use of vap-1 inhibitors for treating fibrotic conditions
Inventor: WESTERLUND NINA
IPC: G01N33/577
Filed: 2010-09-07
Abstract: Discloses a method of diagnosing a fibrotic condition in vitro, said method including: i. assaying the amount of soluble VAP-1 (sVAP-1) or SSAO activity in a sample of bodily fluid, ii. comparing the amount of sVAP-1 or SSAO activity to the amount of sVAP-1 or SSAO activity in a reference bodily fluid, and iii. diagnosing fibrosis on the basis of said amount of sVAP-1 or SSAO activity, wherein a positive diagnosis is indicated by elevated levels of 10 sVAP-1 or SSAO activity in the sample of bodily fluid; and wherein said diagnosing includes determining the degree of fibrosis.
Patent NZ-619382-A (NZ)
Title: Voting party pre-selection method
Inventor: MATTHEW SOLTAU
IPC: G06Q50/26
Filed: 2013-12-23
Abstract: Disclosed is a method of ranking of political parties associated with a preselected set of issues and policies identified and rated by a user as being important in order of their personal preference. The method includes the steps of: (i) storing political policies and upcoming bills into a database; (ii) rating of issues by user; (iii) rating of policies related to those issues by user; and (iv) ranking of political parties based on policy rating of the user weighted by the issue rating of the user stored into a database by the user; (v) awarding scores ranging from -10 to 10 depending on selection and rating of issues and policies; (vi) setting default scores on party policies which may be altered by the user; and (vii) processing of rating of issues and ranking to generate a “How-to-Vote” card. The method may be performed using an application running on a mobile phone or smart television.
Patent NZ-631539-A (NZ)
Title: Systems and methods for treating an opioid-induced adverse pharmacodynamic response
Inventor: KYLE DONALD J
IPC: A61P25/04
Filed: 2013-04-17
Abstract: Disclosed herein is the use of an effective amount of buprenorphine for treating or preventing an opioid-induced adverse pharmacodynamic response, wherein the other opioid is selected from the group consisting of oxycodone, morphine, codeine, oxymorphone, fentanyl, hydrocodone, hydromorphone, tramadol, a phannaceutically acceptable salt thereof and mixtures thereof, and wherein the adverse phannacodynamic response is selected from the group consisting of bowel dysfunction, nausea, vomiting, sonmolence, dizziness, respiratory depression, headache, dry mouth, sedation, sweats, asthenia, hypotension, dysphoria, delirium, miosis, pruritis, urticaria, urinary retention, allodynia, physical dependence and tolerance; and wherein the buprenorphine does not cause a substantial decrease in the analgesic effectiveness of the opioid; and wherein the buprenorphine and the opioid are administered by the same route or by a different route and the route of administration is independently selected from the group consisting of oral, transdennal, sublingual, buccal, gingival, rectal, subcutaneous, intramuscular and intravenous.
Patent NZ-706591-A (NZ)
Title: Oxazolidin-2-one-pyrimidine derivatives
Inventor: RUEEGER HEINRICH
IPC: C07D417/14
Filed: 2013-11-11
Abstract: The present invention relates to oxazolidin-2-one substituted pyrimidine compounds of the formula (I) and/or pharmaceutically acceptable salts thereof, that act as PI3K (phosphatidylinositol-3-kinase) inhibitors, as well as pharmaceutical compositions thereof, methods for their manufacture and uses for the treatment of conditions, diseases and disorders dependent on PI3K.
Patent NZ-714858-A (NZ)
Title: Furniture device with adjustable firmness
Inventor: HYLTENFELDT STEFAN
IPC: A47C27/00
Filed: 2014-05-07
Abstract: The invention relates to a furniture device, such as a bed or mattress, a seat cushion, or other device, is provided to act on the weight or part of the weight of a being. Depending on how the device distributes the weight of the being, it will appear as soft or firm. The degree of firmness is usually set during manufacturing. Contemporary furniture devices often comprise elastic members/ devices with a so-called pocket spring design, however, the known pocket spring design mattresses cannot be combined with mechanisms that allow the adjustment of the firmness of the spring without losing the ability to deform itself without affecting the adjacent springs. The invention provides a holding arrangement and at least one section comprising a base, a movable plate element, a moving mechanism and at least one elastic device, the plate element configured to interact with the at least one elastic device that is moved by the moving mechanism in respect to the base in order to adjust the firmness of at least one elastic device. The holding arrangement comprises a connecting portion and a holding member, which is connected to the at least one elastic device via the connecting portion, such that the at least one elastic member is compressed and relaxed over its entire length during movement of the plate element in a respective direction, wherein the connecting portions are arranged on a straight line, which extends through the centre of two or more attached elastic devices.
Patent NZ-716825-A (NZ)
Title: Immuno-oncolytic therapies
Inventor: THORNE STEPHEN
IPC: C12N15/39
Filed: 2014-08-22
Abstract: The present invention relates to oncolytic vaccinia viruses which have been modified to promote anti-tumor immunity and/or reduce host immunity and/or antibody response against the virus. It is based, at least in part, on the discovery that oncolytic vaccinia virus (i) bearing a genome deletion of a gene that reduces T cell immunity (interleukin-18 binding protein); (ii) treated with a sialidase enzyme which is believed to reduce TLR2 activation and therefore the antibody response; (iii) carrying a gene that enhances cytotoxic T lymphocyte induction (e.g., TRIF) and/or (iv) reduces tumor myeloid-derived suppressor cells by reducing prostaglandin E2 reduces tumor growth. Accordingly, the present invention provides for immunooncolytic vaccinia viruses and methods of using them in the treatment of cancers.
Patent NZ-724949-A (NZ)
Title: Configuring terminal devices
Inventor: FRIEDLI PAUL
IPC: H04L12/24
Filed: 2015-05-13
Abstract: The invention relates to configuring terminal devices in, for example, an access control system or an elevator system. Configuring of terminal devices is known, but these configurations are not optimised for use with a device identifier that is input into the device. Thus, the present invention provides a method, comprising: receiving, using a terminal device (220, 222) in a building, a device identifier for the terminal device; sending the device identifier from the terminal device (220, 222) to a configuration server (210); receiving configuration information for the terminal device (220, 222) from the configuration server (210), the configuration information comprising a physical location of the terminal device (220, 222) in the building; and configuring the terminal device (220, 222) based on the configuration information.
Patent NZ-736143-A (NZ)
Title: Water birthing apparatus
Inventor: MACBETH MATTHEW
IPC: A61B17/42
Filed: 2016-03-18
Abstract: Water birthing apparatus (10) for use in a bath (11) sized to accommodate an adult woman in childbirth, the bath having a base wall and one or more side walls extending upwardly from the base wall to an upper edge portion, defining an open top, the apparatus including: a false floor (14) sized to cover at least some of the base wall of the bath and including an upper face and drainage means (20) for draining water from above the false floor to below the false floor; a birthing chair (19) mounted to the upper face of the false floor; and lifting means (15) associated with the false floor and operable for moving the false floor between a lower position at which the false floor is adjacent or resting on the base wall and an elevated position at which the false floor is spaced above the base wall, wherein the lifting means includes a plurality of lifting arms connected to the false floor and extending from a movable carriage assembly (12) mounted to a carriage track, the carriage assembly being vertically movable along the carriage track. The invention ameliorates the risks associated with traditional water birthing such that water birthing may be reliable and efficient in use.
Patent NZ-738953-A (NZ)
Title: Production method for nitrogen-containing heterocyclic compound, and intermediate of said nitrogen-containing heterocyclic compound
Inventor: MURAKAMI TATSUYA
IPC: C07D239/48
Filed: 2016-07-14
Abstract: The present invention addresses the problem of providing an industrial production method for a nitrogen-containing heterocyclic compound that has an excellent FLT3-inhibiting activity and is useful as an active pharmaceutical ingredient of a pharmaceutical agent. Provided is a production method using a compound represented by general formula [14] (in the formula, R1 represents an optionally substituted C1-6alkyl group, and R8 represents a leaving group or the like) or a salt of said compound.
Patent NZ-740264-A (NZ)
Title: Hemostatic material
Inventor: Qin xiao-hua
IPC: A61L24/10
Filed: 2016-09-01
Abstract: Disclosed is a hemostatic material, wherein a thrombin receptor activating agent is covalently coupled to a biocompatible matrix, and the thrombin receptor activating agent retains thrombin receptor activating activity after covalent coupling to the biocompatible matrix.
Patent NZ-742011-A (NZ)
Title: Steam cooker and backflow prevention device thereof
Inventor: YUAN CHAO
IPC: A47J27/09
Filed: 2018-04-27
Abstract: In prior art, a seal member depends on its weight to seal a backflow prevention device, which is unreliable, so that the liquid in a pot can diffuse out when the pot is drawn up. To solve this problem, the present disclosure provides a backflow prevention device includes an upper chassis, a lower chassis, a seal member, and a resilient member. The upper chassis defines a receiving space passing through a bottom of the upper chassis. The lower chassis defines an air flow channel. A part of the lower chassis is accommodated in the receiving space of the upper chassis, and fixedly connected to an inner wall of the upper chassis. The upper chassis and the lower chassis are mounted to a pot. The seal member is received in the receiving space. The resilient member is resiliently mounted between the seal member and the upper chassis. The resilient power of the resilient member pushes the seal member to resist against and seal the air flow channel. The backflow prevention device further comprises a nozzle fixed to a main body of a steam cooker and configured to be inserted into the air flow channel to push the seal member upwards, and the nozzle defines a cross groove.
Patent NZ-746718-A (NZ)
Title: Variable spring rate chassis
Inventor: HOLMAN MICHAEL
IPC: E05B63/16
Filed: 2017-03-23
Abstract: It is often difficult or impossible to specify a single spring design to work satisfactorily for both knob and lever door lock interfaces. Conventional approaches require distinct chassis configurations for knob interfaces and lever interfaces. An apparatus including a common chassis assembly having a housing, a spindle rotatably mounted to the housing, a spring collar rotatably mounted to the housing, a first biasing element rotationally urging the spindle toward a spindle home position, and a second biasing element rotationally urging the spring collar toward a spring collar home position. The apparatus may further include a handle mounted on the chassis such that the chassis biases the handle to a handle home position with a return torque. The handle may be a knob-type interface or a lever-type interface. The handle is engaged with the spindle such that the first biasing element contributes to the return torque. In certain embodiments, the handle may further be engaged with the spring collar such that the second biasing element contributes to the return torque.
Patent NZ-764519-A (NZ)
Title: Coated adenoviruses for immunotherapy
Inventor: CERULLO VINCENZO
IPC: A61K39/00
Filed: 2015-05-18
Abstract: The present invention relates to adenoviral vectors, wherein the viral capsid has been coated with polypeptides, which are capable of stimulating a peptide-specific immune response in a subject and uses thereof. Furthermore, the present invention relates to methods of treating diseases, e.g. viral infections, by adenoviral vectors which have been coated by polypeptides causing peptide-specific immune response. Also the present invention relates to a method of coating adenoviral vectors by specific peptides as well as to a method of identifying those peptides suitable for coating the capsid of an adenoviral vector.