baber/WOPTO huggingface dataset:
Patent CY-1123419-T1 (CY)
Title: Αντιδραστηρια sirp-αλφα υψηλης συγγενειας
Inventor: RING AARON MICHAEL
IPC: C07K14/47
Filed: 2020-08-27
Abstract: Αντιδραστήρια SIRP-α υψηλής συγγένειας παρέχονται, τα οποία (i) περιλαμβάνουν τουλάχιστον μια αλλαγή αμινοξέος σχετικά με την πρωτεΐνη φυσικού-τύπου˙ και (ii) έχουν μια αυξημένη συγγένεια για CD47 σχετικά με την πρωτεΐνη φυσικού-τύπου. Συνθέσεις και μέθοδοι παρέχονται για διαμόρφωση φαγοκυττάρωσης σε ένα θηλαστικό μέσω χορήγησης μιας θεραπευτικής δόσης μιας φαρμακευτικής σύνθεσης περιλαμβάνοντας ένα αντιδραστήριο SIRPα υψηλής συγγένειας, το οποίο αποκλείει τη φυσιολογική αλληλεπίδραση δέσμευσης μεταξύ SIRPα και του προσδέτη αυτού CD47.
Patent CY-1124001-T1 (CY)
Title: Υγρο αιμοκαθαρσης απαλλαγμενο απο ασβεστιο
Inventor: DE JONG GIJSBERTUS MARIA THEODORUS
IPC: A61K31/194
Filed: 2021-03-17
Abstract: Η εφεύρεση αναφέρεται σε ένα υγρό αιμοκάθαρσης, σε ένα υγρό υποκατάστασης, σε ένα υγρό αιμοκάθαρσης ή ένα υγρό υποκατάστασης για χρήση στη θεραπεία, σε ένα συμπύκνωμα ή τα ξηρά συστατικά του για την παρασκευή ενός υγρού αιμοκάθαρσης ή ενός υγρού υποκατάστασης και σε μια μέθοδο εξωσωματικής κάθαρσης αίματος είτε με αιμοκάθαρση ή με αιμοδιαδιήθηση που περιλαμβάνει: -αιμοκάθαρση ή διαδιήθηση του αίματος με υγρό αιμοκάθαρσης που περιέχει κιτρικό άλας, όπου το υγρό αιμοκάθαρσης είναι ουσιαστικά απαλλαγμένο από ασβέστιο και κατά προτίμηση ουσιαστικά απαλλαγμένο από μαγνήσιο, και -ανάμιξη του αίματος που έχει υποβληθεί σε αιμοκάθαρση με ένα υγρό υποκατάστασης που περιέχει ασβέστιο και κατά προτίμηση μαγνήσιο.
Patent GR-970300016-T1 (GR)
Title: Lactobacillus strains of human origin, their compositions and uses thereof
Inventor: MORELLI LORENZO
IPC: A61K35/74
Filed: 1997-05-30
Abstract: The present invention concerns Lactobacillus strains and pharmaceutical compositions containing them.
Patent SI-1297577-T1 (SI)
Title: Method for producing a photovoltaic thin film module
Inventor: PLESSING ALBERT
IPC: H01L31/048
Filed: 2001-03-05
Abstract: The invention relates to a method for producing a photovoltaic thin film module (1) which is provided with a thin film solar cell system (2) that is mounted on carrier materials (3) and is covered with a compound (4) on at least one side of the surface, whereby said compound consists of an encapsulating material and is provided with a sealing layer (5) on the side of the surface thereof, said side being arranged on the thin film solar cell system (2). According to a covering method, the encapsulating material (4) and the thin film solar cell system (2), together with the carrier (3), are guided along one another and are pressed under pressure and at an increased temperature in such a way that a weather-proof, photovoltaic thin film module in the form of a compound (1) is designed. According to a method that can be carried out easily, a photovoltaic thin film module that is resistant to UV light, water vapour and other effects of the weather is provided. The photovoltaic module can additionally be provided with flexible characteristics by selecting the carrier material in such a way that said material is configured in the form of plastic foils or plastic foil compounds for instance.
Patent SI-1490424-T1 (SI)
Title: Polymers in a solid state
Inventor: SULSER UELI
IPC: C04B24/26
Filed: 2003-03-19
Abstract: Polymer (I), in a solid aggregation state, produced by reacting at least one monomer (a), i.e. an unsaturated mono- or di-carboxylic acid, or analog; at least one monomer (b), i.e. an unsaturated ester or amide of a polymer (B) with one end blocked by a group that is not reactive under normal conditions and, at the other end, a hydroxy or amino group, optionally also an ethylenically unsaturated monomer (c). Polymer (I), in a solid aggregation state, produced by recating at least one monomer (a), i.e. an unsaturated mono- or di-carboxylic acid, or analog; at least one monomer (b), i.e. an unsaturated ester or amide of a polymer (B) with one end blocked by a group that is not reactive under normal conditions and, at the other end, a hydroxy or amino group, optionally also an ethylenically unsaturated monomer (c). (B) has formula X-(EO)x-(PO)y-(BuO)z-R (B) contains less than 20wt.% total PO and BuO groups; has molecular weight120 D to 20kD, especially 250 D to 10kD, and the proportion of (B) with molecular weight below 500 D is less than 50, especially 30, mole%. x, y and x : 0-2500, with total 3 or more; X : hydroxy or NHR'; R' : 1-20C alkyl, 7-20C alkaryl or, preferably, hydrogen; EO, PO and BuO : respectively ethylene, propylene and (iso)butylene residues . Independent claims are also included for the following: (1) method for preparing (I); and (2) solution prepared by dissolving (I) in water.
Patent SI-1949901-T1 (SI)
Title: A method for determining a cholinergic agonist selective for an alpha 7 nicotinic receptor
Inventor: TRACEY KEVIN J
IPC: A61P1/00
Filed: 2003-12-05
Abstract: Methods of inhibiting release of a proinflammatory cytokine from a macrophage are provided. The methods comprise treating the macrophage with a cholinergic agonist in an amount sufficient to decrease the amount of the proinflammatory cytokine that is released from the macrophage, wherein the cholinergic agonist is selective for an ±7 nicotinic receptor. Methods for inhibiting an inflammatory cytokine cascade in a patient are also provided. The methods comprise treating the patient with a cholinergic agonist in an amount sufficient to inhibit the inflammatory cytokine cascade, wherein the cholinergic agonist is selective for an ±7 nicotinic receptor. Methods for determining whether a compound is a cholinergic agonist reactive with an ±7 nicotinic receptor are also provided. The methods comprise determining whether the compound inhibits release of a proinflammatory cytokine from a mammalian cell. Additionally, methods for determining whether a compound is a cholinergic antagonist reactive with an ±7 nicotinic receptor are provided. These methods comprise determining whether the compound reduces the ability of a cholinergic agonist to inhibit the release of a proinflammatory cytokine from a mammalian cell. Oligonucleotides or mimetics capable of inhibiting attenuation of lipopolysaccharide-induced TNF release from a mammalian macrophage upon exposure of the macrophage to a cholinergic agonist are also provided. The oligonucleotides or mimetics consist essentially of a sequence greater than 5 nucleotides long that is complementary to an mRNA of an ±7 receptor. Additionally, methods of inhibiting attenuation of TNF release from a mammalian macrophage upon exposure of the macrophage to a cholinergic agonist are provided. These methods comprise treating the macrophage with the above-described oligonucleotide or mimetic.
Patent SI-2223687-T1 (SI)
Title: (+)-2-(1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl)-4-acetylaminoisoindoline-1,3-dione: Methods of using and compositions thereof
Inventor: SCHAFER PETER H
IPC: C07D209/00
Filed: 2003-03-20
Abstract: Discussed is stereomerically pure (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, or a pharmaceutically acceptable polymorph, salt, solvate or hydrate thereof, as well as a pharmaceutical composition or single unit dosage form comprising such compound and such compound for use as a medicine.
Patent SI-1881225-T1 (SI)
Title: Spring element
Inventor: DIEMER GREGOR
IPC: A47C23/00
Filed: 2007-07-17
Abstract: The spring unit has a base plate (1), and spring arms (2) guided radially outwardly from the base plate. The spring arms are bent on top of each other at its ends pointing away from the base plate. The spring arms carry a support plate (4) in such a manner that the arms, the base plate and the support plate are not overlapped in a spring direction. The adjacent pairs of spring arms are connected with each other in a section, which is connected directly to the base plate, as a single piece.
Patent SI-2167540-T1 (SI)
Title: Heavy chain mutant leading to improved immunoglobulin production
Inventor: GOEPFERT ULRICH
IPC: C12N15/00
Filed: 2008-06-25
Abstract: The current invention comprises a nucleic acid encoding the amino acid sequence of the C-terminal part of the C H 3-domain of an immunoglobulin of the class IgA or IgG, or the C-terminal part of the C H 4-domain of an immunoglobulin of the class IgE or IgM, wherein the glycine-lysine-dipeptide comprised in the amino acid sequence of the C-terminal part of the C H 3- or C H 4-domain is encoded by the nucleic acid ggaaaa, or the nucleic acid ggcaaa, or the nucleic acid gggaaa, or the nucleic acid gggaag, or the nucleic acid ggcaag, or the nucleic acid ggaaag.
Patent SI-2307180-T1 (SI)
Title: Process for manufacturing polyolefin films
Inventor: PETERS MARTINUS WILHELMUS MARIA GEMMA
IPC: B29C43/00
Filed: 2009-06-18
Abstract: A process for manufacturing a film of ultra-high molecular weight polyolefin includes (a) feeding an ultra-high molecular weight polyethylene with a weight average molecular weight of at least 500,000 gram/mole as a powder having a bulk density below 0.5 g/cm3 to a compaction zone of an isobaric double belt press; (b) subjecting the ultra-high molecular weight polyethylene powder in the compaction zone to an isobaric pressure to form a single layer sheet of compacted polyethylene at a temperature that is below the melting point of the polyethylene under process conditions and that is maintained within a temperature window of 2° C.; and (c) subjecting the sheet of compacted polyethylene to a rolling step and at least one stretching step at a temperature below the melting point of the polyethylene under process conditions.
Patent DE-3782725-T2 (DE)
Inventor: WICHMAN WILLIAM JOHN
IPC: E04B1/344
Filed: 1987-12-09
Granted: 1993-06-09
Abstract: A collapsible framework constructed of rods pivotally joined at their ends to hubs to form a self-standing unit when expanded and to fold into a small set of nearly parallel rods when folded. The hubs are designed to pivotally join the ends of four rods, with the plane defined by the pivot axes of one pair of opposing rods being offset from the plane defined by the pivot axes of the other pair of opposed rods attached to the same hub. A stab-connection latch locks two hubs together and secures the framework in the expanded position. Folding channel bars are attached to knobs on vertically aligned hubs by key-slots, the key-slots of one channel bar being of progressively shorter length going from the top-most to the bottom-most of the vertically aligned hubs to which the bar is attached. <IMAGE>
Patent DE-3783933-T2 (DE)
Inventor: SUTHERLAND DEREK R
IPC: A61K31/35
Filed: 1987-03-11
Granted: 1993-07-01
Abstract: Compounds are described of the formula <CHEM>  and salts thereof, wherein  R<1> is methyl, ethyl or isopropyl; R<2> is -H,-OH or substituted-OH and R<3> is-H, or R<2> and R<3> together with the carbon atom to which they are attached represent C=CH2, C=O or C=NOR<6> (where R<6> is-H, alkyl or alkenyl and the C=NOR<6> is in the E configuration);  OR<4> is as defined above for OR<5> and one of the symbols X represents an epoxide oxygen atom and the other represents an epoxide oxygen atom or a carbon-carbon bond. These compounds may be used for controlling insect, acarine, nematode or other pests.
Patent DE-3871774-T2 (DE)
Inventor: KWIATEK DAVID J
IPC: F23Q3/00
Filed: 1988-12-21
Granted: 1992-12-10
Abstract: A gas burner assembly (10) includes an electrically conductive burner cap body (22) with a plurality of burner ports (34) and an ignition port (36) formed in a sidewall of the burner cap body. The burner cap body is connected to an electrical ground potential. An electrically insulative support member (40) is mounted in the ignition port and defines an electrode receiving aperture (42). The support member cooperates with the ignition port to define an ignition gas pathway (44). A spark electrode (24) is positioned within the burner chamber and projects through the support member aperture spaced apart from the ignition gas pathway (44). The spark electrode is selectively connected to a high voltage potential (20) for providing ignition sparks between the electrode and the burner body through the ignition gas pathway.
Patent DE-3879573-T2 (DE)
Inventor: CHESWORTH C O PILKINGTON GLASS
IPC: C03C17/34
Filed: 1988-07-20
Granted: 1993-08-12
Abstract: A bent and/or toughened coated glass is produced by subjecting glass having a coating comprising at least one metal having an atomic number of 22 to 29 and a thin layer of aluminium applied over said coating to a bending and/or toughening cycle in which the coated glass is heated to a temperature above the softening point of the glass. The invention is useful for the production of bent and/or toughened solar control glasses, low emissivity glasses (when the metal used is copper) and mirrors.
Patent DE-3883237-T2 (DE)
Inventor: HALLDORSDOTTIR HILDUR
IPC: A41D13/08
Filed: 1988-03-11
Granted: 1994-01-05
Abstract: PCT No. PCT/SE88/00127 Sec. 371 Date Sep. 20, 1989 Sec. 102(e) Date Sep. 20, 1989 PCT Filed Mar. 11, 1988 PCT Pub. No. WO88/08260 PCT Pub. Date Nov. 3, 1988.A protective cuff for preventing, when working with liquid material at a level above one's shoulders, the liquid material from flowing down onto the person working with the material is constituted by an outwardly open, funnel-like collar (1) of a relatively large rigidity at the inner end thereof somewhat yieldingly carried by a holder (2) forming a bottom for the collar and having a radially inner, axially elongated portion (5) of a soft material and of a relatively small thickness directly enclosing the user's forearm.
Patent DE-60000796-T2 (DE)
Inventor: DOSWALD STEPHAN
IPC: C07D305/12
Filed: 2000-01-21
Granted: 2003-09-18
Abstract: The present invention relates to a method for the purification of lipstatin. More particularly, this invention relates to a method combining liquid-liquid extraction in form of a double-current extraction with a re-extraction in form of a counter-current extraction, as means for isolating lipstatin from crude lipstatin in exceptionally high yield and purity.
Patent DE-60002765-T2 (DE)
Inventor: GEYER KARL WALTER
IPC: G09F3/10
Filed: 2000-02-02
Granted: 2004-02-05
Abstract: Coding to be applied to the bottom side of a packaging. This bottom side is concave, as in a can packaging. The coding comprises an annular label with a central opening and a cutout which extends from the said opening across the entire width of the said label. As a result, it is possible to remove the label from a flat blank and to convert it into a shape which corresponds to the concave bottom side of the said packaging. The invention proposes a device for realising the above. <IMAGE>
Patent DE-60003362-T2 (DE)
Inventor: KELLY ANTOINETTE NORA
IPC: B32B13/04
Filed: 2000-04-20
Granted: 2004-04-29
Abstract: The wall paneling comprises of a facing plasterboard panel (2) that is bonded to, by an adhesive layer (3), to a cork backing panel (4) such that a laminated panel is formed. The cork panel has a density that is of at least 100kg/m3>. The panel assemblies are mounted to a wall structure by a number of equally spaced dabs (7).
Patent DE-60004400-T2 (DE)
Inventor: HAMON JACQUES
IPC: A61P25/04
Filed: 2000-12-19
Granted: 2004-06-09
Abstract: The invention provides a combination of of trimebutine Ä2-dimethylamino-2-phenylbutyl-3, 4, 5- trimethoxy-benzoate hydrogen maleateÜ or its corresponding stereoisomers with an opioid analgesic for the preparation of a medicament to prevent and/or treat pain or nociception.
Patent DE-60006902-T2 (DE)
Inventor: CREVOISERAT JEAN-MICHEL
IPC: C23C8/24
Filed: 2000-03-15
Granted: 2004-10-28
Abstract: A nitriding or carbonitriding furnace atmosphere regulating probe (1) comprises modules (10, 11, 12) for hydrogen measurement and ammonia cracking. Probe (1) for regulating the gas atmosphere in an atmospheric or low pressure nitriding or carbonitriding furnace comprises a connection module (3) for connecting the probe (1) to the furnace (2), a first hydrogen measuring module (10) for measuring residual hydrogen in sampled furnace gas, a cracking module (11) for cracking residual ammonia in sampled furnace gas, a second hydrogen measuring module (12) for measuring all the residual hydrogen, a flow regulating module (13) and a suction module (14) for sampling furnace gas.
Patent DE-60009530-T2 (DE)
Inventor: TOCQUE BRUNO
IPC: C12Q1/6837
Filed: 2000-09-12
Granted: 2005-02-03
Abstract: The present invention describes new methods for the determination of the potential toxicity of test compounds, as well as the kits and tools for the implementation of these methods. The invention also describes methods for generating nucleic acid sequences that can be used as genetic markers of toxicity. The invention is based in particular on the creation of differential nucleic acid banks characteristic of situations in which cell viability and/or proliferation are deregulated, and on the demonstration that these banks can be used to evaluate the toxicity profile of compounds with reliability and high sensitivity. The invention is of special utility in the pharmaceutical industry for analysis of the toxicity profile of compounds involved in drug development and/or in pharmaceutical compositions.
Patent DE-60011575-T2 (DE)
Inventor: SIMERAY JANICK
IPC: G06K7/08
Filed: 2000-02-10
Granted: 2004-10-14
Abstract: This toy is associated with a range of accessories, and includes: one or more central processing units, (1), comprising a microprocessor or microcontroller, incorporated into the toy-proper (10); an autonomous electrical supply intended to supply said central processing unit with electrical energy; an assembly of one or more sensors (4) and/or actuators (5) connected to interfaces integrated into the central processing unit or units (1) and intended to carry out functions of various types at least one inductive coupler (3) connected to the central processing unit or units (1) These accessories (14, 15, 16) associated with the toy (10) each include at least one inductive label (8) intended to interact electromagnetically with said inductive coupler (3). The inductive coupler (3) connected to the central processing unit or units (1) is a current of defined frequency and the inductive coupler exchanges with said inductive labels (8) binary data corresponding to phase or amplitude states of the frequency modulation.
Patent DE-60014927-T2 (DE)
Inventor: POMPIER JEAN-PIERRE
IPC: B60B21/02
Filed: 2000-07-13
Granted: 2006-02-02
Abstract: The invention concerns an assembly consisting of a rim (10) and a supporting element S for a running tread having a diameter DN not less that the diameter of any part of the rim (10) between the outer end of said bearing (11) and the end of the rather low projection (15') axially extending outside said first rim seat (13') sloping outwards, a second rim seat (13'') being diametrically larger than the first rim seat (13'). Said first rim seat (13') is axially extended by a tapered part (17) defined by the circular end, of diameter D'A, axially inside said seat (13') and by the axially outer end of diameter DN of the rim bearing (11), the diameter DN being greater than the diameter D'A by an amount not less than 0.02 DN, and said rim bearing (11) being provided with at least a circumferential groove (110, 115) wherein is housed a circumferential protuberance (30, 30', 30'') of the surface radially inside the support element S having axial width l less than the width L of the rim bearing (11).
Patent DE-60015072-T2 (DE)
Inventor: LAROCHE FRANCIS
IPC: B65H3/08
Filed: 2000-05-24
Granted: 2005-12-15
Abstract: The invention concerns a method for unstacking sheets stacked in a feeder, comprising a step which consists in bringing a vacuum cup close to the surface of the sheet at the top of the stack; a step which consists in contacting the vacuum cup with the surface of said top sheet and a step in bringing the vacuum cup away after seizing the top sheet. The invention is characterized in that the vacuum cup is applied in an off-center zone of the top sheet, and said vacuum cup is inclined, when it starts to move away, so as to cause the top sheet to be deformed thereby producing a separation prior to complete separation of the top sheet.
Patent DE-60020389-T2 (DE)
Inventor: SABDE M
IPC: B24B37/26
Filed: 2000-07-19
Granted: 2006-04-27
Abstract: Methods and apparatuses for planarizing microelectronic substrate assemblies on fixed-abrasive polishing pads with non-abrasive lubricating planarizing solutions. One aspect of the invention is to deposit a lubricating planarizing solution without abrasive particles onto a fixed-abrasive polishing pad having a body, a planarizing surface on the body, and a plurality of abrasive particles fixedly attached to the body at the planarizing surface. The front face of a substrate assembly is pressed against the lubricating planarizing solution and at least a portion of the fixed abrasive particles on the planarizing surface of the polishing pad. At least one of the polishing pad or the substrate assembly is then moved with respect to the other to impart relative motion therebetween. As the substrate assembly moves relative to the polishing pad, regions of the front face are separated from the abrasive particles in the polishing pad by a lubricant-additive in the lubricating planarizing solution.
Patent DE-60022350-T2 (DE)
Inventor: NICULESCU ADRIAN IOAN
IPC: F16F9/06
Filed: 2000-06-05
Granted: 2006-06-22
Abstract: An automative self-adjustable damper having a progressive damping characteristic meant to be used with vehicles for damping the swing of the wheels, chassis, carosserie, the drivers and passengers seats, the engine set as well as in parachoke bars for impact energy absorbtion. This shock absorber is made up of several systems: energy dissipation system, rod volume compensation system, the guiding scaling system and the resistance part protecting all these systems.
Patent DE-60025170-T2 (DE)
Inventor: HAZEN STAN
IPC: G01N33/68
Filed: 2000-02-18
Granted: 2006-08-10
Abstract: Screening methods for asthma and analogous diseases in which activated eosinophils are found at the disease site are provided. The methods involle assaying for the presence of brominated tyrosine species in a bodily sample which has been obtained from a test subject. The brominated tyrosine species are either free in the sample or protein bound. In one embodiment, the assay involve measuring the amount of a brominated tyrosine species, particularly 3-bromotyrosine, 3,5-dibromotyrosine, or combinations thereof (referred to hereinafter collectively as the "diagnostic marker") in a bodily sample from the test subject. In another embodiment for determining the prognosis of asthma in a test subject, the concentration or content of the diagnostic marker is determined in bodily samples taken from the test subject over successive time intervals. The concentrations are compared to determine the prognosis of the asthma. In another embodiment of the invention for monitoring the response of the test subject to treatment with an anti-asthmatic drug, the concentration or content of the diagnostic marker is measured in bodily samples obtained from the test subject before and after such treatment. The present invention also relates to a diagnostic kit and to a diagnostic reagent for diagnosing asthma and analogous diseases which are associated with activated eosinophils.