baber/WOPTO huggingface dataset:
Patent CA-2937299-A1 (CA)
Inventor: BUFFE CLOTHILDE
IPC: C07D493/04
Filed: 2015-01-21
Abstract: The main subject matter of the present invention is a process for producing bis-anhydrohexitol ether compositions and in particular isohexide glycidyl ether compositions, one of the originalities of which is azeotropic distillation carried out under reduced pressure. Such compositions are used to produce epoxy resins, the function thereof being to form a three-dimensional macromolecular network. The compositions obtained according to the invention are rich in diepoxy derivatives of isosorbide to the detriment of monoepoxy derivatives, only the first participating in the formation of the three-dimensional network. The crosslinking density is therefore increased, thereby making it possible to obtain a material which is more chemically resistant and mechanically stronger and which has a higher glass transition temperature (Tg), compared with the same materials obtained with bis-anhydrohexitol ether compositions according to the prior art.
Patent CA-2942560-A1 (CA)
Inventor: RIZZO PERRY
IPC: H04B7/24
Filed: 2016-09-20
Abstract: There is provided a control box for monitoring industrial machinery, comprising a processor, a memory and one or more communication interfaces in communication with the processor. The processor is configured to receive status data from one or more machines; store the status data in the memory; generate one or more of audio notification data and visual notification data based on the status data; transmit the notification data to one or more status beacons; transmit the status data to one or more computing devices; receive feedback data from the computing devices; and transmit the feedback data to the corresponding one or more machines. There is also provided a system for monitoring industrial machinery, comprising the control box and the status beacon configured to receive the notification data, and in response, produce one or more of a corresponding audio notification and a corresponding visual notification.
Patent CA-2942887-A1 (CA)
Inventor: BIERBACH ULRICH
IPC: C07F15/00
Filed: 2015-03-15
Abstract: Newly synthesized thiourea-modified 3-chloro-4-fluoroanilio-quinazoline derivatives have been studied, as terminal carrier ligands in linear gold(l) complexes. The molecules mimic the tyrosine kinase inhibitor gefitinib (by computational docking experiments). Thiourea groups were either directly attached to quinazoline-C6 or linked to this position via a flexible ethylarmino chain. One compound tested acts as a thiourea-S/quinazoline-Nl mixed-donor ligand, giving an unusual dinuclear complex as determined by X-ray crystallography and/or electrospray mass spectrometry. One compound formed the desired stable linear complex. The biological activity of the carrier ligands and corresponding gold(l) complexes was studied in NCI-H460 and NCI-H1975 lung cancer cells. One compound that was tested partially overcomes resistance to gefitmib in NCI-H1975 (with IC 50 values of 1.7 and 30 µM, respectively), and the corresponding gold complex (13) maintains activity in the low-micromolar concentration range.
Patent CA-2943420-A1 (CA)
Title: Method for making bismuth-containing liquid pharmaceutical suspensions
Inventor: GILBERT STEVEN RAY
IPC: A61K31/29
Filed: 2015-04-29
Abstract: A method of producing a liquid pharmaceutical suspension by mixing magnesium aluminum silicate, gellan gum, bismuth subsalicylate, and methyl cellulose.
Patent CA-2945276-A1 (CA)
Inventor: ORCHARD BRIAN KEITH
IPC: E04B1/38
Filed: 2016-10-14
Abstract: A deck clip magazine for use with a pneumatic fastener gun and a plurality of generally T-shaped deck clips attached to one another by webbing to form a clip belt. The deck clip magazine has a housing with a channel shaped to receive the clip belt and a front end with an opening to permit egress of the leading clip from the channel. An aperture on the housing is aligned with the barrel of the pneumatic fastener gun and permits fasteners to pass therethrough to secure the generally T-shaped clips in position. The clips are aligned below the aperture by way of an inwardly biased movable stop located adjacent the opening. A cutting mechanism is aligned with the webbing and selectively actuated to sever the webbing between adjacent clips in the clip belt.
Patent CA-2947028-A1 (CA)
Inventor: STANDING IAIN
IPC: G05B19/418
Filed: 2015-04-30
Abstract: In a method of configuring a host device in a process control plant to automatically perform an action or a set of actions includes, a workflow template is generated. The workflow template includes a sequence of one or more steps to be performed by the host device. Each of at least some of the one or more steps is selected from a set of predetermined steps. Then, an instance of the workflow template is generated at the host device. A trigger condition is generated for automatically triggering the instance workflow. The sequence of the one or more steps is executed in response to detecting the trigger condition.
Patent CA-2947705-A1 (CA)
Title: Compositions containing polymeric sulfur and uses thereof
Inventor: DUNN KELLY
IPC: A61P31/00
Filed: 2016-11-07
Abstract: This invention relates to personal care compositions and methods of treating topical skin conditions using compositions containing polymeric sulfur S n. The compositions of this invention may also preferably contain ~SH-containing compounds such as thiols.
Patent CA-2950142-A1 (CA)
Inventor: HART DENNIS L
IPC: F17D3/00
Filed: 2009-08-17
Abstract: A pipeline pressure testing assembly has a fitting defining a flow path and having a port on a wall of the fitting into which a pressure testing device is removably inserted along a central axis of the port for pressure testing. The port is circular, larger than the interior diameter of the pipeline and located at or above the tube forming the flow path through the fitting. The fitting has a recess encircling at least part of the flow path and opening to the port to receive the testing and sealing devices. The recess is formed by two opposing walls inclined relative to the central axis of the recess. The recess walls at the top of the flow path by the port are spaced apart a distance as large as the pipe diameter for cleanout and inspection. A tubular valve stem screws into the testing device and has a rotary valve blocking flow through the tubular valve stem. Flow through the fitting is blocked with the rotary valve closed and the tubular valve stem in a first position. Flow through the testing device is allowed with the rotary valve closed and the tubular valve stem in an open position. With the rotary valve open, flow through the tubular valve stem is permitted when the tubular valve stem is in either the first or second position to provide multiple drain and fill options.
Patent CA-2950246-A1 (CA)
Title: Method for controlling a pump arrangement
Inventor: FULLEMANN ALEXANDER
IPC: F04D15/00
Filed: 2015-06-01
Abstract: The invention relates to a method for controlling a pump arrangement upon clogging of a pump, the pump arrangement comprising a pump and a control unit, the pump comprising a motor, and the control unit being arranged to drive said motor, the motor during operation being associated with an operational parameter from which the torque of the motor may be derived, said operational parameter has a normal value PN during normal operation of the motor in a first direction. The method being characterized by the steps of driving the motor in a first direction by means of the control unit, stopping the motor if a real value P of the operational parameter exceed a predetermined clogging limit PI, where PI = 1,05*PN, driving the motor in a the first direction opposite second direction a predetermined flushing time TR by means of the control unit, and stopping the motor if the absolute value of the real value P of the operational parameter during the flushing time TR exceed the absolute value of a first unfastening limit PL1, where | PL1I = 1, 1*PI, otherwise stopping the motor after said flushing time TR and returning to normal operation.
Patent CA-2950329-A1 (CA)
Title: Horizontal shaft impact crusher hammer lifting device
Inventor: FORSBERG ANDREAS
IPC: B02C13/26
Filed: 2014-06-19
Abstract: A crusher hammer lifting device (63) to facilitate raising and lowering a hammer (46) mountable at a rotor of a horizontal shaft impact crusher (HSi-crusher). The device comprises a main body (64), a mount engager (67) for attachment to an auxiliary lifting tool and a hammer attachment (83) for releasable mounting a hammer in a rotatable manner at the device.
Patent CA-2952090-A1 (CA)
Inventor: LINDNER KARL-HEINZ
IPC: B21D11/06
Filed: 2015-05-19
Abstract: A method and a system for producing open or closed annular structural components made of light metal and alloys thereof, preferably of magnesium or magnesium alloys, having a two-dimensional or three-dimensional structure by means of extrusion, wherein the extruded profile exiting the die of the extrusion press is formed into a helical shape by way of one or more guide tools, and more particularly such that the ends of the helical shape are separated from the extruded strand in the region of the overlap and formed into a two-dimensional or three-dimensional structural component in a shaping device.
Patent CA-2954145-A1 (CA)
Inventor: MOHANTY RASHMI RANJAN
IPC: C21D9/46
Filed: 2015-07-03
Abstract: L'invention concerne un procédé de production d'une tôle d'acier haute résistance ayant une limite d'élasticité YS > 850 MPa, une résistance à la traction TS > 1 180 MPa, un allongement total > 13 % et un taux d'expansion de trou HER > 30 %, par traitement thermique d'une tôle d'acier la composition chimique de l'acier, contenant: 0,13 % = C = 0,22 %, 1,2 % = Si = 1,8 %, 1,8 % = Mn = 2,2 %, 0,10 % = Mo = 0,20 %, Nb = 0,05 %, Ti < 0,05 %, Al = 0,5 %, le reste étant constitué de Fe et des impuretés inévitables. La feuille est recuite à une température de recuit TA > 865 °C et <1000 °C pendant une durée de plus de 30 s, puis trempée par refroidissement à une température de trempe QT compris entre 275 °C et 375 °C, à une vitesse de refroidissement > 30 °C/s afin d'obtenir, juste après la trempe, une structure constituée d'austénite et d'au moins 50 % de martensite, la teneur en austénite étant telle que la structure finale peut contenir entre 3 % et 15 % d'austénite résiduelle et entre 85 % et 97 % de la somme de martensite et de bainite sans ferrite, puis chauffée à une température de séparation (PT) comprise entre 370 °C et 470 °C et maintenue à cette température pendant une durée Pt comprise entre 50 s et 150 s, puis refroidie à température ambiante
Patent CA-2956482-A1 (CA)
Inventor: SCHIFFER-MANNIOUI CECILE
IPC: C12N15/62
Filed: 2015-07-29
Abstract: The present invention relates to a new generation of chimeric antigen receptors (CAR) referred to as multi-chain CARs, which are made specific to the antigen ROR1. Such CARs aim to redirect immune cell specificity and reactivity toward malignant cells expressing the tumor antigen ROR1. The alpha, beta and gamma polypeptides composing these CARs are designed to assemble in juxtamembrane position, which forms flexible architecture closer to natural receptors, that confers optimal signal transduction. The invention encompasses the polynucleotides, vectors encoding said multi-chain CAR and the isolated cells expressing them at their surface, in particularly for their use in immunotherapy. The invention opens the way to efficient adoptive immunotherapy strategies for treating cancer, especially chronic lymphocytic leukemia or solid tumors.
Patent CA-2959451-A1 (CA)
Inventor: OHNISHI KEISUKE
IPC: H02M7/483
Filed: 2014-08-29
Abstract: An inverter equipped with: a first transistor (Q1) connected between a first input terminal (T1) and an output terminal (T4); a second transistor (Q2) connected between the output terminal (T4) and a second input terminal (T2); first and second diodes (D1, D2) connected in anti-parallel to the first and second transistors (Q1, Q2); and a bidirectional switch including third and fourth transistors (Q3, Q4) and third and fourth diodes (D3, D4), and connected between a third input terminal (T3) and the output terminal (T4). The first and second transistors (Q1, Q2) and the third and fourth diodes (D3, D4) are formed from a wide-bandgap semiconductor, while the third and fourth transistors (Q3, Q4) and the first and second diodes (D1, D2) are formed from a semiconductor other than a wide-bandgap semiconductor.
Patent CA-2960082-A1 (CA)
Inventor: MAKINEN ESA
IPC: B01F15/04
Filed: 2015-09-01
Abstract: The invention relates to an apparatus (1) and a method for dispensing a wash solution, which is to be conveyed into a washing device, at a desired concentration of detergent chemical. The apparatus comprises a first tank (8) for a wash solution at a desired concentration. The tank includes elements (3, 5, 4, 6, 18, 19) for supplying the first tank with an aqueous solution of supply water and a detergent chemical, elements (2) for measuring the total amount of supply water, and elements (11, 12) for conveying the wash solution at a desired concentration from the first tank (8) into a washing device. The supply water passed through the measuring elements (2) is divided into partial flows along at least two lines (3, 18; 4, 19), which are provided with valve elements (5, 6) for adjusting the partial flows of supply water at a desired ratio between the lines. At least one line (4, 19) for the partial flows of supply water is connected to a detergent chemical supply (10) for conveying the detergent chemical along with water into the tank (8), and at least one second line (3, 18) is intended for the supply of plain water. The apparatus comprises at least one second tank (7), which is equipped with a siphon (13) and into which at least a detergent chemical-containing partial flow is adapted to be conveyed and conducted further into the first tank (8) by way of the siphon (13). The second tank (7) is provided with a first surface level sensing element (16) which indicates the attainment of a certain design volume in the second tank (7), whereby the water quantity measuring elements (2) register the indication moment about the attainment of a design volume and the amount of water which has flown through the measuring elements at the indication moment and which provides a basis for determining the concentration of a detergent chemical in the second tank (7).
Patent CA-2961788-A1 (CA)
Title: Hard surface cleaners comprising ethoxylated alkoxylated nonionic surfactants
Inventor: DI CAPUA GLORIA
IPC: C11D1/83
Filed: 2015-10-21
Abstract: The need for a liquid hard surface cleaning composition which provides improved shine, reduced slipperiness during drying, and also improved drying times is met formulating the composition using a ethoxylated alkoxylated nonionic surfactant, in combination with a detersive surfactant.
Patent CA-2963533-A1 (CA)
Inventor: KAPPES MATTHEW J
IPC: F02C7/20
Filed: 2017-04-06
Abstract: According to one aspect, a flange fastening assembly for a gas turbine engine includes a first flange having a first hole therein, a second flange having a second hole disposed adjacent to the first flange, and a shoulder bolt disposed through the first hole and the second hole. The shoulder bolt has a head portion, a stem portion, and a thread portion, and the stem portion and the thread portion define a shoulder. A bolt nut is disposed on the thread portion and a first spacer is disposed between the bolt nut and the first flange such that the first spacer overhangs the shoulder.
Patent CA-2966220-A1 (CA)
Title: Method for the management of biology in a batch process
Inventor: WALKER LEE RICHARD
IPC: C02F11/04
Filed: 2015-10-28
Abstract: A method for the treatment of organic waste, the method comprising alternating steps of anaerobic digestion and aerobic composting conducted in a single reactor vessel, wherein at or about the completion of the anaerobic digestion step at least a portion of any free draining fluid from the reactor vessel is directed for reuse in subsequent anaerobic digestion steps, and solids remaining in the reactor vessel from the anaerobic digestion step are subjected to a dewatering step from which a liquid is obtained that is ultimately also directed, at least in part, for reuse in subsequent anaerobic digestion steps. A method for the management of biology in a batch process, wherein the batch process is an anaerobic digestion process, is also described.
Patent CA-2966424-A1 (CA)
Title: Method for improving duration of effect of dermal filler treatment
Inventor: MURPHY DIANE K
IPC: A61Q19/08
Filed: 2015-10-30
Abstract: A method of treating midface volume deficit in a person is provided. The method generally includes administering a dermal filler, such as a hyaluronic acid based dermal filler, in a sequence of injections that enhance effectiveness and/or duration of the filler. The method may include initially introducing a volume of the filler into at a zygomaticomalar region of the face prior to introducing one or more additional volumes of the filler into the anteromedial region and the submalar region, such that the duration of effectiveness of the treatment is improved, and less filler is required to achieve a desired correction.
Patent CA-2967314-A1 (CA)
Inventor: POGGEL STEFFEN
IPC: F02C6/08
Filed: 2017-05-15
Abstract: The invention relates to an arrangement (1, 15), comprising a turbomachine (2, 16) with a compressor (3) having an outlet (7), and with a bleed air line (9), through which a leakage flow can flow and which is connected via a controllable valve (8) to the outlet (7) of the compressor (3), for supplying the leakage flow to a unit, characterized in that the unit is designed as a fan (17), jet pump (10) or pump which can be driven by the leakage flow.  The invention also relates to a method for operating the arrangement (1, 15).
Patent CA-2968009-A1 (CA)
Title: Generation of browser suggestions based on internet of things device data
Inventor: PATTEN MICHAEL J
IPC: G06Q30/00
Filed: 2015-12-16
Abstract: Systems, methods and computer program products are described herein that collect and analyze data generated by embedded systems included within a user's devices to generate recommendations for presentation to the user within the context of the user's web browser. The recommendations may comprise, for example, suggested information resources and/or search queries. Such recommendations may be presented to the user as part of a new tab page or within an address bar of the web browser's graphical user interface. In accordance with further embodiments, the user device data is used by a search engine to generate search results, and/or a ranking of search results.
Patent CA-2971283-A1 (CA)
Title: Foldable bed
Inventor: BRUN NICOLAS
IPC: A47C19/12
Filed: 2015-09-18
Abstract: A foldable bed (50) comprising: - a frame (505) that can be folded according to at least one axis comprising a foldable rod (510), - at least two legs (515), each leg being attached to the frame by a link (520), said link allowing said leg to be positioned in a deployed position and in a folded position and - the foldable rod being associated with each link to either side of the folding axis, in which: - each link comprises an opening (525) that passes through said link, and - each leg comprises an attachment (530) to a flexible wire (535) linking two legs and passing through the folding axis of the frame, the wire being tensioned when the rod is unfolded, the tension of the wire moving the legs to be positioned in the deployed position.
Patent CA-2971672-A1 (CA)
Title: Moyens et methodes pour presenter des peptides cycliques sur des particules bacteriophages
Inventor: URBAN JOHANNES HERBERT
IPC: C12N15/10
Filed: 2015-12-21
Abstract: La présente invention concerne des méthodes d'exposition de peptides cycliques sur la surface de particules bactériophages, et des collections de celles-ci.
Patent CA-2973978-A1 (CA)
Title: Treatment of cancer with anti-lap monoclonal antibodies
Inventor: WEINER HOWARD L
IPC: A61K39/395
Filed: 2016-01-14
Abstract: Described herein are compositions and methods relating to LAP-binding agents, including, for example, anti-LAP antibodies, and to their use in methods of treatment of cancer. LAP-binding agents affected both systemic and intra-tumor immunity and were shown effective to treat a broad spectrum of cancer types.
Patent CA-2974954-A1 (CA)
Inventor: JONES DANIEL
IPC: C12Q1/6851
Filed: 2017-08-01
Abstract: Disclosed is a highly sensitive mutation-specific quantitative polymerase chain reaction (PCR) assay to detect BTK mutations in B cells.
Patent CA-2976270-A1 (CA)
Inventor: STINSON JOHN F
IPC: B65H75/00
Filed: 2016-03-17
Abstract: The present disclosure is directed to a core-roll that contains areas of anti-slip material and methods of making the core-roll. The core-roll has one or more anti-slip zones to allow a continuous paper web to be wound around the core without the need for additional physical restraint to keep the paper from shifting laterally along the core. In another embodiment, the disclosure describes a parent roll having an anti-slip core-roll that does not interfere with other operations that occur during converting.
Patent CA-2977436-A1 (CA)
Inventor: BONIG HALVARD
IPC: G01N33/80
Filed: 2016-02-25
Abstract: The present invention provides a cellular system for the detection of the presence of one or more antibody species in sample, preferably a serum or plasma sample. The method is in particular useful for the analysis of patients who have been sensitized against blood group antigens expressed on erythrocytes, platelets or granulocytes. The system uses fluorescence labeled cells specific for each antigen and hence, for each antibody species. Provided are the methods, system and diagnostic kits for performing the methods of the invention. In addition, the present invention discloses a method for removing antibodies from a sample such as a serum sample. Such a method is useful for absorbing antibodies from poly-agglutinating sera.
Patent CA-2977945-A1 (CA)
Title: Scanning environments and tracking unmanned aerial vehicles
Inventor: HAMMOND ASA
IPC: G05D1/02
Filed: 2016-03-02
Abstract: Systems and methods for scanning environments and tracking unmanned aerial vehicles within the scanned environments are disclosed. A method in accordance with a particular embodiment includes using a rangefinder off-board an unmanned air vehicle (UAV) to identify points in a region. The method can further include forming a computer-based map of the region with the points and using the rangefinder and a camera to locate the UAV as it moves in the region. The location of the UAV can be compared with locations on the computer-based map and, based upon the comparison, the method can include transmitting guidance information to the UAV. In a further particular embodiment, two-dimensional imaging data is used in addition to the rangefinder data to provide color information to points in the region.
Patent CA-2980173-A1 (CA)
Inventor: STAMETS PAUL EDWARD
IPC: A61K31/37
Filed: 2016-03-31
Abstract: Compounds having unique antiviral properties found in mushroom mycelium and their analogs are extracted, concentrated, isolated, synthesized or manufactured to create compositions useful in preventing the spread and proliferation of various viruses afflicting animals, particularly viruses harming humans, pigs, birds, bats, or bees. Such compounds and compositions can be used individually or in combination with known medicines or natural products such as mushroom mycelium and extracts of mushroom mycelium to improve health.
Patent CA-2982522-A1 (CA)
Inventor: VAN BERKEL PATRICIUS HENDRIKUS CORNELIS
IPC: A61K47/68
Filed: 2016-04-15
Abstract: Site-specific antibody-drug conjugates are described, in particular conjugates comprising pyrrolobenzodiazepines (PBDs) having a labile protecting group in the form of a linker. The site of conjugation, along with modification of the antiobody moiety, allows for improved safety and efficacy of the ADC.