baber/WOPTO huggingface dataset:
Patent EP-1047708-A1 (EP)
Title: Peptide chelators that predominately form a single stereoisomeric species upon coordination to a metal center
Inventor: POLLAK ALFRED
IPC: A61K38/00
Filed: 1998-12-23
Abstract: The labeling of biologically important molecules via a bifunctional chelator can result in the formation of isomers or multiple species, which can have significant impact on the biological properties of the radiopharmaceutical. For receptor-based radiopharmaceuticals, the target uptake is largely dependent on the receptor binding affinity of the targeting molecule and the blood clearance of the labeled molecule, which is determined by the physical properties of both the targeting molecule and the metal chelate. Hence, the presence of isomers for the metal chelate can have significant impact on the radiopharmaceutical. Therefore, in the development of a radiopharmaceutical or metallodrug, it is necessary to separate the isomers and evaluate the biological activities of each individual isomer. It would therefore be desirable to develop chelators that predominately form only a single stereoisomeric species upon coordination to a metal center. Disclosed herein are chelators that form a mixture enriched for a single stereoisomeric species upon coordination to a metal center.
Patent EP-0945576-A1 (EP)
Inventor: FRECHEN MANFRED
IPC: E06B1/70
Filed: 1999-03-11
Abstract: The assembly to secure facade sections has at least one holder unit for mounting to the brickwork. It has a section to hold the facade section, at right angles to the plane of the brickwork, and a fitting for mounting the facade section to the holder. Preferably the holder is an extruded profile or a profiled multi-chamber unit, of polyvinyl chloride.
Patent EP-0959175-A1 (EP)
Inventor: JAKOB HARALD DR
IPC: D06L4/30
Filed: 1999-05-18
Abstract: Mixtures consisting of formamidine-sulfinic acid (FAS), at least one scale inhibitor and/or finely divided silica.
Patent EP-1081423-A1 (EP)
Inventor: VIEGENER WALTER
IPC: F16L13/14
Filed: 1999-08-17
Abstract: The method is used for producing a connection between a press fitting (1) and the end of a pipe (3) inserted into a socket (2) on the fitting which contains a sealing ring (5). It comprises using a forming tool (8) to shape the ring before or during the insertion of the pipe end, after which the fitting and pipe are cold worked to seal them together. An Independent claim is included for the forming tool.
Patent EP-1098070-A1 (EP)
Inventor: MAGOSHI RYOTARO
IPC: F01D25/12
Filed: 1999-11-03
Abstract: A steam turbine includes a rotor (1) which extends along a
longitudinal axis and having at least two different pressure turbine
portions (3,4) disposed around and along the rotor (1). Each of the
turbine portions (3,4) has multiple stages. A casing (2) encloses the
rotor (1) and has at least one steam inlet (6). A dummy ring (10) is
provided stationarily around the rotor (1) to separate and seal between
the two different pressure turbine portions (3,4). The dummy ring (10)
defines a nozzle chamber (13) for receiving the steam from the steam
inlet port (6) and a plurality of nozzles for directing the steam from
the nozzle chamber toward the higher pressure turbine portion (3). The
dummy ring (10) and the casing (2) define a space therebetween. The
space is fluidly connected to the higher pressure turbine portion (3). A
steam passage (22) extends between the space and a steam passage
downstream of the last stage of the higher pressure turbine portion (3).
The steam passage (22) allows the steam within the space to flow to the
steam passage downstream of the last stage of the higher pressure
turbine portion (3) to cool the casing (2).
Patent EP-1006602-A1 (EP)
Inventor: HATAZAWA TSUYONOBU
IPC: H01M50/562
Filed: 1999-11-25
Abstract: A nonaqueous electrolyte battery is disclosed which is capable of improving
impact resistance while airtightness of a laminate film is being maintained. When a
battery element is accommodated in a casing constituted by a laminate film and the
case is welded to enclose the battery element, a resin layer is provided for at least one
surface of a battery element. The resin layer may be a resin plate which has previously
been molded or the resin layer may be formed by enclosing resin. The resin layer is
provided for two sides of all of the sides of the battery element which have smallest
areas. In a case of a wound-type battery element, the resin layer is provided for the
two end surfaces of the wound battery element. The resin layer has a shock buffering
function to protect the battery element from impact.
Patent EP-0969321-A1 (EP)
Inventor: MERKEL PAUL BARRETT
IPC: G03C7/392
Filed: 1999-06-12
Abstract: The invention disclosed is a photographic element comprising a
support bearing at least one silver halide emulsion and at least one high-boiling
solvent of structure I, below:
 
wherein:
   m is 0, 1 or 2;   each R 1  is an individually selected alkyl group with up to four carbon
atoms;   n is 2 to 5;   each R 2  and R 3  may be the same or different and is individually selected
from hydrogen or an alkyl group with up to four carbon atoms;   p is 0 to 3;   each R 4  is independently a methyl or ethyl group; and   the sum of the number of carbon atoms in each R 1  plus each R 2  plus each
R 3  plus each R 4  taken together is three to seven.
Patent EP-1026006-A1 (EP)
Inventor: HUTCHISON BRUCE STANLEY JOHN
IPC: B42F7/08
Filed: 1999-01-06
Abstract: A collapsible and extendible file assembly is formed from card or other
semi-rigid bendable material. It comprises an outer casing 1 with an
opening front panel 3 provided with foldable struts 9 which fold on crease
lines 9' and when folded out prop a box-like part of the casing 1
comprising panels 5, 7, 8 apart from the front panel 3 thus allowing
compartments 31 to open and hang down. The compartments 31 are for
the storage of documents and are demarcated longitudinally by dividers 18
attached at each end to a respective concertina panel 20 attached to rear
panel 7 of the box-like part. 
     To be accompanied when published by Figure 7 of the drawings.
Patent EP-0956962-A1 (EP)
Inventor: HELTERLINE BRIAN L
IPC: B41J2/01
Filed: 1999-05-07
Abstract: The present disclosure relates to replaceable printing component (14) for an ink-j et
printing system (10) having at least one replaceable printing component. The
replaceable printing component (14) includes an electrical storage device (38)
responsive to printing system control signals for transferring information between the
printing component (14) and the ink-jet printing system (10). The electrical storage
device (38) includes a tag family identifier for selecting a family of tags from a
plurality of families of tags. Also included is a plurality of tags associated with
replaceable printing component (14) parameters. Each of the plurality of tags has a
tag value associated therewith. Wherein the ink-jet printing system (10) reads the tag
family identifier from the electrical storage device (38) to select the family of tags.
Each tag of the plurality of tags read by the ink-jet printer (12) is identified based on
the selected family of tags and is used to identify the associated replaceable printing
component (14) parameter.
Patent EP-1016662-A1 (EP)
Inventor: HYODA SHUNJI
IPC: C07D257/04
Filed: 1999-08-27
Abstract: A process for the preparation of a 5,5'-bi-1H-tetrazole
diammonium salt by dropwisely adding the aqueous
hydrogen peroxide to which a small amount of weakly acidic
substance has been added, to a starting aqueous solution
containing hydrogen cyanide or sodium cyanide or potassium
cyanide, sodium azide and a catalytic amount of copper
sulfate preferably at a low temperature to maintain the pH
of the reaction solution over a range of from 5 to 6,
heating the reaction solution to effect the oxidation and
cyclization reaction, reacting the reaction product with
ammonium chloride or an aqueous solution thereof, and
recovering the formed ammonium salt in the form of
sparingly soluble crystals. The desired product is
obtained in a high yield and in a high purity from the
starting materials which are cheaply available and are
easy to handle through a decreased number of steps, i.e.,
through a one-pot reaction without requiring cumbersome
after-treatment.
Patent EP-1014377-A1 (EP)
Inventor: MEADOWS HAROLD BRETT
IPC: G11C7/06
Filed: 1999-12-13
Abstract: A current sensing differential amplifier with
high rejection of power supply variations and method
for an integrated circuit memory device which allows
the amplifier's differential voltage level and speed
to track that of the sense amplifier supplying the
information, thereby achieving the needed margin for
critical synchronous timing. The reliability of the
differential amplifier is also increased due to the
provision of a larger differential signal and higher
supply voltage levels. In a preferred embodiment, an
n-channel transistor serves as a regulator with its
drain terminal coupled to an unregulated supply
voltage source ("V CC "). The gate of the transistor is
then coupled to a regulated supply voltage ("V CCP ")
which is a function of the voltage supply for the
sense amplifier. The source of the transistor is
connected to the sources of the p-channel transistors
in the main amplifier which provide feedback to the
main amplifier. Consequently, the source side of the
feedback transistors cannot go to a voltage higher
than V CCP  - V tn  (the threshold voltage of the n-channel
transistor), even for wide variations in voltage on
the V CC  voltage source.
Patent EP-0930650-A1 (EP)
Inventor: JULIEN JEAN-NOEL
IPC: H01L23/427
Filed: 1999-01-18
Abstract: The heat exchanger comprises thermal exchange unit (2) with the component and several cooling tubes (5) containing heat exchanging fluid. The outer edges of these tubes form rigid plate (4) connecting adjacent edges (4c,4d) in a group of heat exchangers, which are generally assembled in coplanar form, exhibiting modular assemblies.
Patent EP-0933278-A1 (EP)
Inventor: LE GARREC ROGER
IPC: B61D3/18
Filed: 1999-01-22
Abstract: A pivoting platform (2) is added above the flat freight car (1) to enable the rapid loading of a truck waiting at the edge of one lateral platform as soon as the truck carried by the freight car is unloaded onto a second lateral platform. The pivoting platform is activated by hydraulic jacks and carried by rollers (7). The rollers are mounted between coupled crossmembers (8) composed of two U-shaped sections centered on the platform pivoting axis.
Patent EP-0977037-A1 (EP)
Inventor: RUTISHAUSER MARCEL
IPC: G01N33/553
Filed: 1999-07-14
Abstract: A sliding magnetic separator with a carrier (2) containing at least one test tube, and with a vertically mobile magnetic device (4) able to reach the test tubes to be in direct contact with them, comprises another position next to the magnetic device (4) over which the carrier can be moved.
Patent EP-1101837-A1 (EP)
Inventor: CURRO' GIUSEPPE
IPC: H01L23/522
Filed: 1999-11-22
Abstract: The invention relates to a method of producing a protective inhibitor
layer of moisture-generated corrosion for aluminum (Al) alloy
metallization layers (1), particularly in semiconductor electronic devices. 
     The method of this invention comprises chemically treating the
metallization layer (1) in at least two steps using a mixture of
concentrated nitric acid and trace phosphoric acid, in order to produce
a thin protective phosphate layer (3). 
     Alternatively, the method comprises dipping the electronic device at
least once in a mixture of a polar organic solvent and phosphoric acid
(H 3 PO 4 ) or phosphate derivatives thereof in low percent amount, e.g.
with a phosphate reactant such as orthophosphoric acid or even R-H x PO y ,
where R is an alkaline type of ion group or an alkyl radical. 
     The thin film (3) is formed on top of a thin layer (2) of native aluminum
oxide hydrate Al 2 O 3 .xH 2 O.
Patent EP-1046067-A1 (EP)
Inventor: DAMES ANDREW NICHOLAS
IPC: A61B5/06
Filed: 1999-01-05
Abstract: A uni-directional tag for use with position and orientation detection systems, which is not affected by exposure to high magnetic field levels. The tag is constructed from special geometry of magnetic materials and is applicable for example to catheter location systems.
Patent EP-1085037-A1 (EP)
Inventor: NAGANO SHINICHI
IPC: C08L23/08
Filed: 1999-02-01
Abstract: The water shield sheet according to the present
invention comprises an ethylene/α-olefin copolymer (A)
which is a copolymer of ethylene and an α-olefin of 3 to
20 carbon atoms and which has an MFR in the range of 0.05
to 10 g/10 min, a density (d) in the range of 880 to 935
kg/cm 3 , and a relation between a temperature (Tm (°C )) at
the maximum peak position in an endothermic curve, as
measured by DSC, and a density (d (kg/cm 3 )), of  Tm < 0.4
x d - 244 , and a quantity fraction (W) of n-decane-soluble
component at room temperature of not higher than 3.0 % by
weight. 
     The water shield sheet has excellent mechanical
strength such as tensile strength and strength and
elongation at tear strength and elongation at penetration,
as well as excellent flexibility and fusion properties.
Patent EP-1048083-A1 (EP)
Inventor: PRELAS MARK A
IPC: H02S99/00
Filed: 1999-01-15
Abstract: A heat and electrical energy conversion device using diamond or other single or polycrystalline substances as a storage medium. A radioactive isotope is impregnated into the diamond crystalline structure so that the interstitial voids between the carbon atoms of the diamond structure are each occupied by an atom of the radioactive isotope. However, other wide band-gap materials, such as the typical wide band-gap direct transition materials that include silicon carbide (SiC), gallium nitride (GaN), and aluminium nitride (AlN), also can be used, depending on the desired photoluminescence wavelengths. The crystal lattices produce electromagnetic radiation in response to charged particle irradiation, e.g., the EXCITON mechanism or emission due to color centers, defects or vacancies effect to provide a conversion of the emitted particles to photons, which subsequently are converted to electrical energy with photovoltaic devices. The devices can be assembled in to cells and the cells wired into modules.
Patent EP-1046312-A1 (EP)
Inventor: RIETKERK PAUL
IPC: H04Q3/00
Filed: 1999-01-05
Abstract: Intelligent network (IN), comprising at least one Service Switching Point, SSP (2), at least one Service Control Point, SCP (3), one or more Intelligent Peripherals, IPs (5), and/or one or more Voice Response Systems, VRSs (4), which IN is capable of interacting with a PSTN or ISDN (1). The essence of the concept is an additional interface, in the form of a control member (6), between the IPs and/or VRs on one side and the Service Control Point(s) on the other side. Such makes it possible that the (advanced) IPs and VRSs are capable of exchanging all sorts of information with the SCP, without the IPs or VRSs consequently being occupied for an extended period of time. As a result, the SCP may dispose of (additional) information which in a regular IN cannot be made available to the SCP(s).
Patent EP-1074151-A1 (EP)
Inventor: SNAPE THOMAS JOSEPH
IPC: H04Q3/00
Filed: 1999-02-05
Abstract: L'invention concerne un réseau de télécommunications dans lequel on met en oeuvre un espacement des appels de réseau intelligent au sein d'une fonction de commande d'appel, afin de rejeter des appels automatiquement de manière sélective lorsqu'il est nécessaire de réduire la charge propre au réseau intelligent. Etant donné que la fonction de commande d'appel est le point au niveau duquel se fait la première reconnaissance d'un appel de réseau intelligent, la configuration décrite permet de réduire les ressources de traitement absorbées par le rejet d'appel et d'accélérer la réaction au rejet d'appel de réseau intelligent.
Patent EP-1054870-A1 (EP)
Title: Poisons topoisomerase heterocycliques
Inventor: LAVOIE EDMOND J
IPC: A61P31/10
Filed: 1999-02-12
Abstract: L'invention concerne un poison topoisomérase de la formule (I) dans laquelle R1-R8 ont n'importe laquelle des significations définies dans la description, ou alors un sel de ce poison acceptable du point de vue pharmaceutique; l'invention concerne également des compositions pharmaceutiques comprenant un composé de la formule (I) ou un sel de ce composé, des intermédiaires utiles dans la préparation d'un composé de la formule (I) et des méthodes thérapeutiques comprenant l'administration d'un composé de la formule (I) ou d'un sel de ce composé.
Patent EP-1000241-A1 (EP)
Inventor: REMBOLD HELMUT
IPC: F02M55/02
Filed: 1999-02-10
Abstract: Bei Kraftstoffversorgungsanlagen mit zwei in Reihe geschalteten Kraftstoffpumpen werden bei V-Motoren zwei Kraftstoffverteilerleisten vorgesehen. Hier bestand bisher das Problem, dass zum Regeln des Drucks in den beiden Kraftstoffverteilerleisten ein ziemlich hoher Aufwand erforderlich war und/oder die Regelung des Drucks nicht mit der gewünschten Güte geschehen konnte. Bei der hier vorgeschlagenen Kraftstoffversorgungsanlage kann mit dem einen Drucksteuerventil (30) bei einem Minimum an zu verlegenden starren Leitungen eine gute Druckregelung in den beiden Kraftstoffverteilerleisten (21, 22) erreicht werden. Die Kraftstoffversorgungsanlage ist für eine Brennkraftmaschine eines Fahrzeugs vorgesehen.
Patent EP-1063892-A1 (EP)
Inventor: LAWRENCE ERIC CLAY
IPC: A21C9/08
Filed: 1999-03-09
Abstract: A dough ball loader includes a conveyor belt supported on a frame. A frame plate is fixed in position over the conveyor belt. Loading tubes on the frame plate are aligned over a loading opening in the frame plate. Pairs of flatteners are pivotably attached to the frame plate adjacent to the loading opening. The flatteners preferably have a flat bottom surface. An actuator is linked to the flatteners and pivots the flatteners from an open position for loading dough balls onto the conveyor belt, to a closed position, for flattening the dough balls and fixing them into position on the belt.
Patent EP-1082109-A1 (EP)
Inventor: NISHII HIROYUKI
IPC: A61K31/155
Filed: 1999-04-26
Abstract: An oral formulation comprising a biguanide and an organic acid has less unpleasant tastes such as bitterness and saltiness.
Patent EP-1092282-A1 (EP)
Inventor: ZSCHEILE JOHN WALTER JR
IPC: H04B7/005
Filed: 1999-06-15
Abstract: L'invention porte sur un procédé relatif à une liaison de données multimode à canal double, permettant de moduler ou d'attribuer une quantité prédéterminée de puissance pour chacun des deux canaux. Il est possible de transmettre à partir d'une station principale deux produits de signaux distincts sur une liaison descendante à destination de plusieurs stations au sol, qui les recevant, déterminent individuellement l'intégrité de chacun des produits de signaux, et renvoient l'information correspondante ainsi qu'un identificateur de station à la station principale, qui traite ladite information et réattribue un pourcentage prédéterminé de la puissance totale à émettre sur chacun des deux canaux afin d'obtenir une intégrité prédéterminée du produit reçu par au moins l'une des stations au sol.
Patent EP-1090272-A1 (EP)
Inventor: STOREY JOHN J
IPC: G01C25/00
Filed: 1999-06-25
Abstract: L'invention concerne un procédé pour calculer des phases relatives entre des voies de signalisation dans un dispositif de poursuite à capteurs multiples. Les phases relatives peuvent être utilisées pour calibrer le dispositif de poursuite à capteurs multiples en vue d'atteindre une plus grande précision. Le procédé consiste à enregistrer une pluralité de premiers signaux générés par une première voie du dispositif de poursuite à capteurs multiples pendant un mouvement dudit dispositif. Le dispositif de poursuite à capteurs multiples inclut généralement plusieurs voies comprenant chacune au moins un capteur pour détecter un mouvement par rapport à un axe correspondant. En même temps que l'enregistrement de la pluralité de premiers signaux, une pluralité de deuxièmes signaux générés par une deuxième voie du dispositif de poursuite à capteurs multiples est enregistrée. La pluralité de deuxièmes signaux est générée pendant le mouvement du dispositif de poursuite à capteurs multiples. Ensuite, une phase relative entre la première voie et la deuxième voie est calculée en fonction de la pluralité de premiers signaux et de la pluralité de deuxièmes signaux enregistrés.
Patent EP-1099206-A1 (EP)
Inventor: INSTANCE DAVID JOHN
IPC: G09F3/02
Filed: 1999-07-16
Abstract: A label for a product, or a promotional device, including a flexible light emitting polymer screen.
Patent EP-1029889-A1 (EP)
Inventor: UEMATSU HIROSHI
IPC: C10B53/07
Filed: 1999-08-27
Abstract: A treatment process for resins or organic compounds,
or waste plastics containing them, whereby a portion of
the resins or organic compounds, or waste plastics
containing them are subjected to combustion treatment in
a blast furnace while the remainder is subjected to
thermal decomposition treatment in a coke oven.
Patent EP-1109582-A1 (EP)
Inventor: FUNG YUEN KAI
IPC: C12N5/10
Filed: 1999-08-18
Abstract: La présente invention concerne une nouvelle approche de thérapie génique appliquée à des zones restreintes telles que des tumeurs. La démarche décrite ici consiste à: (a) placer un gène d'intérêt dans un vecteur plasmidique entraîné par un promoteur inductible par la chaleur ou par la lumière; (b) modifier ce vecteur par inclusion d'une protéine de fusion sensible à la tétracycline et agissant comme activateur de transcription, ce qui permet de réguler l'expression du gène en jouant sur la concentration du médicament et; (c) modifier ce vecteur en incluant des séquences d'ADN qui réduisent ou suppriment l'expression de gènes dans des cellules normales de voisinage. L'invention concerne aussi un ensemble de vecteurs à expression tant continue que régulable. Sont également décrits de nouveaux vecteurs destinésà la thérapie génique des cancers du sein, des ovaires et de la prostate, localisés ou métastatiques.
Patent EP-0986824-A1 (EP)
Inventor: VAN DULMEN HENDRIKUS A M
IPC: H01J5/60
Filed: 1999-03-22
Abstract: The electric lamp comprises a lamp vessel (1) and a cap (10) having integrally a housing (11) and an intermediate spring part (15) with connecting means (17) on it. The cap (10) is supplied with means for contacting (14) and referencing (9). The spring part (15) keeps the lamp positioned on a carrier (30) by a permanent press force. The electric lamp is compact, can be simply assembled and can be used in front-, back- and plate-mounting, possibly in combination with an adapter (25).
Patent EP-1113834-A1 (EP)
Inventor: SHAIKH AMER
IPC: A61M16/04
Filed: 1999-09-15
Abstract: An intubation device comprises an airway tube (10) a distal end of which is surrounded by an inflatable cuff (12) which is shaped and dimensioned to lie, in use, between the soft palate and the laryngeal inlet posteriorly of the palatopharyngeal folds. When inflated the cuff (12) has roughly the shape of the frustum of a four-sided pyramid with rounded corners and tapers away from its distal end. The distal end of the tube (10) is recessed ID into the distal end of the cuff so that the latter is an annular protrusion (13) adapted to straddle the upper region of but not to surround the elliptical epiglottis (14) and to fill the piriform fossae (15) on either side thereof.
Patent EP-1109938-A1 (EP)
Inventor: KLEIN CHRISTOPH
IPC: C12Q1/68
Filed: 1999-09-17
Abstract: The present invention relates to a novel method for the amplification of DNA, this method being particularly useful for the amplification of the DNA or the whole genome of a single cell, chromosomes or fragments thereof. Described is also the use of the method in DNA analysis for medical, forensic, diagnostic or scientific purposes, like comparative genomic hybridization (CGH)-, fluorescence in situ hybridization (FISH)-, polymerase chain reaction (PCR)-, single strand conformation polymorphism (SSCP)-, DNA sequence-, "loss of heterozygosity" (LOH)-, fingerprint- and/or restriction fragment length polymorphism (RFLP)- analysis.