baber/WOPTO huggingface dataset:
Patent EP-4142879-A1 (EP)
Inventor: BERENSHTEYN FRADA
IPC: C12N5/079
Filed: 2021-04-26
Abstract: The present invention provides ocular cells, genetically modified by a CRISPR system targeting the expression of B2M for ocular cell therapy. The invention further provides methods of generating an expanded population of genetically modified ocular cells, for example limbal stem cells (LSCs) or corneal endothelial cells (CECs), wherein the cells are expanded involving the use of a LATS inhibitor and the expression of B2M in the cells has been reduced or eliminated. The present invention also provides cell populations, preparations, uses and methods of therapy comprising said cells.
Patent EP-4142736-A1 (EP)
Inventor: DEISHER THERESA
IPC: A61K31/573
Filed: 2021-04-28
Abstract: The present disclosure relates to novel therapies and associated methods of treatment based on newly provided therapeutic mechanisms mediated by the binding of glucocorticoids to intercellular adhesion molecules (ICAMs).
Patent EP-4168517-A1 (EP)
Title: Composition aqueuse pour la lubrification des systemes mecaniques
Inventor: DE BARROS BOUCHET MARIA ISABEL
IPC: C10N40/25
Filed: 2021-06-21
Abstract: Composition aqueuse pour la lubrification des systèmes mécaniques La présente invention concerne une composition lubrifiante aqueuse pour la lubrification des pièces en mouvement dans un système mécanique comprenant au moins de l'eau; du glycérol; et de l'hypéricine. Elle concerne encore l'utilisation d'une telle composition lubrifiante aqueuse, pour la lubrification des pièces en mouvement dans un système mécanique, en particulier dans un système de propulsion de véhicule. Figure pour l'abrégé : Néant
Patent EP-4153095-A1 (EP)
Inventor: HAULON STEPHAN
IPC: A61F2/07
Filed: 2021-05-20
Abstract: L'invention concerne un dispositif de remplacement d'une racine aortique mobile entre une configuration déployée et une configuration repliée, ledit dispositif comprenant - un stent intraventriculaire (1) comprenant une partie proximale et une partie distale, ledit stent intraventriculaire (1) étant évasé depuis la partie proximale vers la partie distale de manière à ce que lorsque le dispositif est déployé dans le ventricule au-dessous de la valve aortique il soit maintenu en position dans le ventricule; - un ensemble de valve aortique (7); - un stent aortique (5) s'étendant depuis le stent intraventriculaire (1); le stent intraventriculaire (1), l'ensemble de valve aortique (7) et le stent aortique (5) formant un ensemble unitaire en configuration repliée et en configuration déployée, le stent aortique (5) comprenant au moins trois moyens de connexion du dispositif aux artères coronaires.
Patent EP-4159500-A1 (EP)
Title: Door module with peripheral seal
Inventor: MIRA PALACIOS JORGE
IPC: B60J5/04
Filed: 2021-05-25
Abstract: The present invention relates to a module for doors, tailgates or similar, to be installed in vehicles for the insulation of the wet areas from the dry areas of the structures of said doors, tailgates or similar, executed by means of a process of bi-injection or multiple injection, in which a monoblock module with regard to the support panel and the seal is formed, its configuration including a sealing gasket with at least two sealing lips inclined towards the inside of the support panel with respect to the assembly direction, one of them being configured to not overlap with the other lip.
Patent EP-4171800-A1 (EP)
Title: Process for producing a porous alpha-alumina catalyst support
Inventor: CHOI SUNG YEUN
IPC: B01J35/10
Filed: 2021-06-25
Abstract: A process for producing a porous alpha-alumina catalyst support, comprising i) preparing a precursor material comprising, based on inorganic solids content, at least 50 wt.-% of a transition alumina having a loose bulk density of at most 600 g/L, a pore volume of at least 0.6 mL/g and a median pore diameter of at least 15 nm; and at most 30 wt.-% of an alumina hydrate; ii) forming the precursor material into shaped bodies; and iii) calcining the shaped bodies to obtain the porous alpha-alumina catalyst support. The catalyst support has a high overall pore volume, thus allowing for impregnation with a high amount of silver, while keeping its surface area sufficiently large so as to provide optimal dispersion of catalytically active species, in particular metal species. The invention further relates to a shaped catalyst body for producing ethylene oxide by gas-phase oxidation of ethylene, comprising at least 15 wt.-% of silver, relative to the total weight of the catalyst, deposited on a porous alpha-alumina catalyst support obtained in the process described above. The invention also relates to a process for preparing a shaped catalyst body as described above comprising impregnating a porous alpha-alumina catalyst support obtained in the process described above with a silver impregnation solution, preferably under reduced pressure; and optionally subjecting the impregnated porous alumina support to drying; and b) subjecting the impregnated porous alpha-alumina support to a heat treatment; wherein steps a) and b) are optionally repeated. The invention further relates to a process for producing ethylene oxide by gas- phase oxidation of ethylene, comprising reacting ethylene and oxygen in the presence of a shaped catalyst body as described above.
Patent EP-4086287-A1 (EP)
Inventor: LI ZONGHAI
IPC: C12R1/91
Filed: 2021-01-04
Abstract: Provided is an antibody or antigen binding fragment, capable of recognizing an antigen peptide comprising SEQ ID NO: 7 (KNKKIYDGG); or recognizing an epitope comprising SEQ ID NO: 7 in Claudin 18.2; preferably recognizing a peptide comprising SEQ ID NO: 6 (KNKKIYDGGART); or recognizing an epitope comprising the SEQ ID NO: 6 in the Claudin 18.2.
Patent EP-4165218-A1 (EP)
Inventor: LI XIANG
IPC: C12Q1/70
Filed: 2021-06-11
Abstract: The present disclosure provides methods and compositions for the detection of SARS-CoV-2 by CRISPR/Cas collateral RNAse activity.
Patent EP-4205268-A1 (EP)
Inventor: REIMNITZ DIRK
IPC: B60K1/02
Filed: 2021-06-23
Abstract: Die Erfindung betrifft eine elektrische Maschinenanordnung (1 ), umfassend eine erste elektrische Maschine (21 ), eine zweite elektrische Maschine (22) mit jeweils einem Stator (31, 32) und mit jeweils einem Rotor (41, 42), umfassend ferner ein gemeinsames Gehäuse (7), in dem die beiden elektrischen Maschinen (21, 22) axial benachbart zueinander angeordnet sind, sowie umfassend eine in drehfestem Kontakt mit dem Rotor (41 ) der ersten elektrischen Maschine (21 ) stehende Abtriebswelle (101 ) und eine in drehfestem Kontakt mit dem Rotor (42) der zweiten elektrischen Maschine (22) stehende Abtriebswelle (102). Dabei ist der Rotor (41 ) der ersten elektrischen Maschine (21) auf seiner der zweiten elektrischen Maschine (22) abgekehrten Seite über ein erstes Lager (611) drehbar gelagert in oder an einem Stützteil (S) des Gehäuses (7) radial abgestützt angeordnet und ist der Rotor (42) der zweiten elektrischen Maschine (22) auf seiner der ersten elektrischen Maschine (21) abgekehrten Seite über ein zweites Lager (612) drehbar gelagert in oder an einem Stützteil (S) des Gehäuses (7) radial abgestützt angeordnet. Einer der beiden Rotoren (41, 42) ist auf seiner dem anderen Rotor (42, 41 ) zugekehrten Seite über ein drittes Lager (613) radial gegen den anderen Rotor (42, 41 ) abgestützt. Erfindungsgemäß ist der Rotor (41 ) der ersten elektrischen Maschine (21 ) oder der Rotor (42) der zweiten elektrischen Maschine (22) über ein viertes Lager (614) radial abgestützt.
Patent EP-4182918-A1 (EP)
Inventor: GONTIER MATHIEU
IPC: G10K11/172
Filed: 2021-07-16
Abstract: The noise barrier (1) is arranged to be used in an apparatus which produces noise during operation and which comprises at least one blower (7) for generating an airflow (6) along a path through the apparatus. The noise barrier (1) has one or more through holes (2) and is configured to be placed in the path of the airflow (6) for attenuating sound which propagates along this path in the airflow. It is made of at least one sound attenuating polymeric foam, in particular a polyurethane foam. In order to achieve better sound attenuating properties the polymeric foam of the noise barrier has an airflow resistivity, measured in accordance with ISO 9053-1:2018, Part 1, which is higher than 50 000 Ns/m4. Moreover, the dynamic Young's modulus of the polymeric foam is preferably smaller than 250 kPa.
Patent EP-4168710-A1 (EP)
Inventor: KESSSELS MARCUS JOZEF HENRICUS
IPC: F21S41/148
Filed: 2021-06-23
Abstract: An LED lamp (1) for a vehicle light, the LED lamp (1) comprising a retrofit body (112) defining a longitudinal direction and being integrally configured as a heat sink, a conductive structure (13) being arranged in a cavity of the retrofit body (12) and at least one LED module (11) being electrically connected to the conductive structure (13), the at least one LED module (11) comprising a substrate (111) and a diode semiconductor (112) applied onto the substrate (111); a retrofit body (12), a conductive structure (13), and a method for manufacturing an LED lamp (1) for a vehicle.
Patent EP-4175800-A1 (EP)
Inventor: HILLER ALEXANDER
IPC: B26B19/38
Filed: 2021-06-22
Abstract: A grooming device. The grooming device includes a handle having a neck portion, a displacement sensor positioned within the neck portion, a housing portion, a coupling mechanism securing the neck portion and the housing portion to one another, and a power source positioned within the handle. The neck portion includes a proximal end and a distal end. The proximal end of the neck portion having an implement connecting structure. The housing portion includes a proximal end, a distal end, and a location element. The proximal end of the housing portion is pivotably connected to the distal end of the neck portion about a handle pivot axis. As the neck portion pivots about the handle pivot axis relative to the housing portion, the displacement sensor detects displacement of the location element. A grooming implement is connected to the implement connecting structure.
Patent EP-4070721-A1 (EP)
Title: Wearable device
Inventor: HUANG ZHENLONG
IPC: A44C5/00
Filed: 2021-01-05
Abstract: This application provides a wearable device, including a watch face, a watch band, and a compression band, where the watch face includes a bezel, a bottom cover, and a blood pressure measurement assembly, the bezel is connected to a peripheral edge of the bottom cover and encloses a watch face inner cavity together with the bottom cover, the bottom cover is provided with an outer plug-connection port, an flow passage, and an inner plug-connection port that successively communicate, the outer plug-connection port is closer to the bezel than the inner plug-connection port, the blood pressure measurement assembly is accommodated in the watch face inner cavity, and an air nozzle of the blood pressure measurement assembly mutually communicates with the inner plug-connection port; and the watch band is connected to the bezel, the compression band and the watch band are stacked, and an air nozzle of the compression band mutually communicates with the outer plug-connection port. In the wearable device illustrated in this application, the flow passage is used to isolate the air nozzle of the blood pressure measurement assembly from the air nozzle of the compression band, so as to avoid a problem that an internal component of the wearable device is damaged due to a displacement of the compression band during assembly or disassembly of the compression band, thereby helping prolong a service life of the wearable device.
Patent EP-3950840-A1 (EP)
Inventor: WOO WON HEE
IPC: C08L69/00
Filed: 2021-01-22
Abstract: The present invention provides a polyalkylene carbonate-based resin having excellent thermal stability, thereby having an improved heat shrinkage phenomenon, and a molded article produced using the same. The polyalkylene carbonate-based resin includes 100 parts by weight of a base resin including a polyalkylene carbonate resin and a polylactide resin, and 5 parts by weight to 10 parts by weight of a heat shrinkage prevention agent, wherein the base resin includes the polyalkylene carbonate resin and the polylactide resin in a weight ratio of 6:4 to 4:6, and the heat shrinkage prevention agent is one or more selected from the group consisting of a polyalkyl(meth)acrylate-based resin, a polyalphaolefin-vinyl acetate-based resin, and a polyoxyalkylene-based resin.
Patent EP-4188606-A1 (EP)
Title: Verfahren und vorrichtung zum waschen/reinigen von granulaten aus schlacken sowie rost-/kesselaschen aus der thermischen abfallverwertung sowie mineralische rest- und recyclingstoffe
Inventor: GRONHOLZ CLAUS
IPC: B03B5/00
Filed: 2021-07-27
Abstract: Die Erfindung betrifft ein Verfahren zum Waschen/Reinigen von Granulaten aus Schlacken sowie Rost-/Kesselaschen aus der thermischen Abfallverwertung, bei welchem Verfahren das Granulat in eine Prozessflüssigkeit gegeben und darin mit Ultraschall beaufschlagt wird. Gemäß der Erfindung wird vorgeschlagen, dass sich die Prozessflüssigkeit in einem aufrechten Reinigungskanal mit einem oberen Zuführ-Ende und einem unteren Abführ-Ende befindet, dass das Granulat von dem Zuführ-Ende in den Reinigungskanal eingeführt wird und sich aufgrund der Schwerkraft nach unten in Richtung auf das Abführ-Ende bewegt und während der Sinkbewegung mit Ultraschall beaufschlagt wird.
Patent EP-4190125-A1 (EP)
Inventor: CHRISTMAN STEVEN SCOTT
IPC: H05B3/06
Filed: 2021-07-28
Abstract: A glass product, comprising: a glazing having a connectable material with a connecting surface on the glazing; a connector over the connecting surface including: a sleeve having an opening therethrough adhered over the connecting surface via a first adhesive; and a fitting which fits at least partially within the sleeve and includes a connector plate on a bottom surface and an extension extending from the fitting; and a conductive material within the sleeve; at least part of the conductive material being positioned between the connector plate and the connecting surface.
Patent EP-4189077-A1 (EP)
Title: Lignées cellulaires stables pour la production inductible de virions raav
Inventor: PRENTICE KENNETH
IPC: C12N7/02
Filed: 2021-07-30
Abstract: L'invention concerne des constructions polynucléotidiques et des lignées cellulaires stables pour la production inductible de virions rAAV dans lesquels sont conditionnés des polynucléotides de charge utile.
Patent EP-4188265-A1 (EP)
Title: Systems and devices for retractor interference avoidance
Inventor: AZULAY SHMUEL
IPC: A61B34/10
Filed: 2021-08-01
Abstract: Systems and methods for retractor interference avoidance is provided. At least one retractor includes a base and one or more elongate members extending from the base. The one or more elongate members are movable. A position of the at least one retractor may be determined and a trajectory of a surgical device may be received. At least one elongate member of the one or more elongate members positioned to interfere with movement of the device along a trajectory may be identified based on the position of the retractor and the trajectory of the surgical device.
Patent EP-4193011-A1 (EP)
Inventor: BUCHMÜLLER PATRICK
IPC: D02J1/08
Filed: 2021-08-10
Abstract: Die Erfindung betrifft eine Verwirbelungsdüse (100) für die Herstellung von Knotengarnen, verwirbeltem Garn, von DTY- oder Glattgarnen mit Knoten. Die Verwirbelungsdüse (100) umfasst einen Garnkanal (1) mit einer Luftdrallkammer (2). Die Luftdrallkammer (2) umfasst eine Einblasöffnung (4) zur Einbringung von Luft in die Luftdrallkammer (2). Es erstreckt sich eine Kanalachse (M) in einer Fadenführrichtung (F). Der Garnkanal (1) umfasst eine Kanalbreite (21) quer zu der Kanalachse (M). Die Luftdrallkammer (2) umfasst eine Kammerlänge (29) in Fadenführrichtung (F) und eine Kammerausdehnung (28) quer zu dieser Länge. Die Kammerlänge (29) beträgt mindestens 180% der Kammerausdehnung (28), bevorzugt mindestens 200% der Kammerausdehnung (28), und bevorzugt ist die Kammerlänge (29) mindestens 1.5 mm länger als die Kammerausdehnung (28).
Patent EP-4204048-A1 (EP)
Inventor: MELINIOTIS ANDREAS
IPC: B65D75/58
Filed: 2021-08-24
Abstract: The invention provides a unit dose dispenser in the form of a blister containing a dry powder for inhalation. The blister comprises a base material in which a cavity is formed comprising a bowl that contains the powder and a channel that opens into the bowl. The channel contains a tube that has separate sections that provide an air outlet and an air inlet. The air outlet is further from the bowl than the air inlet. The upper side of the tube is flat and level with the top of the channel. A lid material, such as a foil or foil laminate, seals the cavity. The blister has a detachable portion which, when removed, exposes the air inlet and the air outlet. A process for making the unit dose dispensers is also provided, which is based on the conventional process for manufacturing blister strips for dry powder inhalers.
Patent EP-4182868-A1 (EP)
Inventor: ZHANG WEI
IPC: G06Q20/36
Filed: 2021-08-26
Abstract: A computer-implemented method of validating token transactions, wherein the validating entity has access to a token mint transaction and/or a token setup transaction, wherein the token mint transaction comprises cryptographic minting data, and mints an initial amount of the tokens, wherein the token setup transaction comprises the minting data certified by the token issuer, and wherein the method is performed by a validating entity and comprises: obtaining a target token transaction comprising one or more token inputs and one or more token outputs; and validating the target token transaction, wherein said validating of the target token transaction comprises: verifying that each token input of the target token transaction comprises the minting data, and/or verifying that each token input of the target token transaction references a respective token output of either the token mint transaction or a previously validated token transaction that can be traced back to the token mint transaction.
Patent EP-4210816-A1 (EP)
Title: Dual sensors to control pacing rate
Inventor: YOON HYUN J
IPC: A61N1/365
Filed: 2021-08-23
Abstract: A medical device is configured to generate an acceleration signal and a temperature signal. The device is configured to determine an activity metric from the acceleration signal that is representative of patient physical activity. In response to determining that the activity metric is equal to or greater than a previously determined activity metric, the device is configured to adjust a target cardiac pacing rate based at least on a temperature change determined from the temperature signal. The device may include a pulse generator for generating cardiac pacing pulses based on the target cardiac pacing rate.
Patent EP-4211629-A1 (EP)
Title: Test d'un précurseur de film
Inventor: ROSENBERGER MATTHIAS
IPC: G06Q10/06
Filed: 2021-09-02
Abstract: L'invention concerne un procédé de test d'un précurseur de film (FVP). Selon le procédé, un précurseur de film (FVP) est fourni à un groupe sélectionné de personnes de test (8). Pendant ou directement après la réception du précurseur de film (FVP) par les personnes de test (8), des signaux de réaction (E, ZS) provenant des personnes de test (8) sont détectés dans des sections. Une analyse automatique des signaux de réaction détectés (E, ZS) se produit pour générer des données de résultat d'analyse (BE) pour les sections individuelles (A). Un résultat de test global (GA) du précurseur de film (FVP) est également éventuellement déterminé en fonction des données de résultat d'analyse (B). L'invention se rapporte en outre à un procédé de correction de précurseur de film (FVP). L'invention concerne par ailleurs un dispositif de test de précurseur de film (20). L'invention concerne en outre un dispositif de correction de précurseur de film.
Patent EP-4112665-A1 (EP)
Inventor: SAKAMAKI TOSHIKAZU
IPC: C08F2/50
Filed: 2021-03-22
Abstract: A photocurable composition comprising a photopolymerizable component and a photopolymerization initiator, wherein: in a case in which a test piece P1 with a length of 39 mm, a width of 8 mm, and a thickness of 4 mm, is produced by photofabrication under conditions in which the photocurable composition is irradiated with visible light having a wavelength of 405 nm at an irradiation dose of 12 mJ/cm 2  to form a cured layer P1 with a thickness of 100 µm, the cured layer P1 is stacked in a thickness direction thereof to form a rectangular fabrication product P1 with a length of 39 mm, a width of 8 mm, and a thickness of 4 mm, and the fabrication product P1 is irradiated with ultraviolet rays having a wavelength of 365 nm at an irradiation dose of 10 J/cm 2  to produce the test piece P1, a total fracture work of the test piece P1 measured in compliance with ISO20795-1:2008 is 1100 J/m 2  or more.
Patent EP-4208391-A1 (EP)
Inventor: LOWE TREVOR RAYMOND
IPC: B65D5/54
Filed: 2021-09-02
Abstract: A carton for medicament storage includes a bottom box and a lid. The bottom box includes a bottom wall, a first sidewall, a second sidewall, a back wall, and a front wall. The carton also includes a lid coupled to the bottom box and movable between an open position and a closed position. The bottom box is closed by the lid when the lid is in the closed position. Additionally, the carton includes a release tab comprising a portion of the one of the lid and the second front wall and being defined by a perforated line in the one of the lid and the bottom box. The carton also may include an adhesive positioned on at least a part of the release tab and selectively coupling the lid and the bottom box. When the carton is in the closed position, the release tab is secured to the one of the lid and the bottom box via the perforation and is secured to the other of the lid and the bottom box via the adhesive. Alternatively, when the lid is in the open position, the release tab is separated along the perforated line from the one of the lid and the bottom box and is secured to the other of the lid and the bottom box via the adhesive.
Patent EP-4037538-A1 (EP)
Inventor: SHELTON IV FREDERICK E
IPC: A61B1/06
Filed: 2021-09-29
Abstract: A surgical visualization system (108) may include tiered-access features. The surgical visualization system may be used to analyze at least a portion of a surgical field. Based on a control parameter, the system may assess the present state of moving particles that portion of the surgical field, assess an aggregated state of the moving particles, and/or assess moving particles at a selectable tissue depth. The control parameter may include system aspects such as processing capability or bandwidth for example and/or the identification of an appropriate service tier.
Patent EP-4136669-A1 (EP)
Inventor: COWE ANDREW B
IPC: F16K3/18
Filed: 2021-04-13
Abstract: An isolation valve assembly including a valve body having an inlet and an outlet. The isolation valve includes a seal plate disposed within an interior cavity of the valve body. The seal plate is movable between a first position allowing gas flow from the inlet to the outlet, and a second position preventing gas flow from the inlet to the outlet. The isolation valve includes a closure element disposed within the valve body. The closure element is configured to retain the seal plate stationary in the first position or the second position. The closure element includes a first sealing element positioned adjacent to a first surface of the seal plate. A working surface of the first sealing element is substantially obscured from the gas flow when the seal plate is stationary.