baber/WOPTO huggingface dataset:
Patent WO-2020247447-A1 (WO)
Title: Pyrazole and imidazole derivatives, compositions and methods as orexin antagonists
Inventor: MEKKONEN BELEW
IPC: C07D213/00
Filed: 2020-06-03
Abstract: The present invention is directed to substituted Pyrazole and Imidazole derivatives of compounds that are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved or implicated. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Patent WO-2020257579-A1 (WO)
Inventor: PATTON JAMES
IPC: A63B21/00
Filed: 2020-06-19
Abstract: A joint movement therapy and assistive device system. The system includes a torque profile device having a plurality of connecting components, a longitudinal axis, and a center. Each connecting component of the plurality of connecting components is disposed at a selected distance relative to the center and a selected angle relative to the longitudinal axis. The system also includes at least one segment end and a plurality of tensioning components removable secured to the plurality of connecting components of the torque profile device and the at least one segment end. The plurality of tensioning components forms an additive torque profile when coupled between the torque profile device and the at least one segment end.
Patent WO-2021007539-A1 (WO)
Inventor: BALDWIN JEFFREY
IPC: H01M8/04082
Filed: 2020-07-10
Abstract: Disclosed is a method of: providing a hydrogenated sp 2  carbon allotrope, and releasing hydrogen gas from the carbon allotrope. The method may be used an apparatus having: a vessel for containing the hydrogenated sp 2  carbon allotrope, a fuel cell capable of using hydrogen gas a fuel, and a tube for transporting hydrogen gas from the vessel to the fuel cell. The carbon allotrope may be made by: providing a mixture of an sp 2  carbon allotrope and liquid ammonia, adding an alkali metal to the mixture, and sonicating the mixture to form a hydrogenated form of the carbon allotrope. The hydrogenated carbon can be at least 3.5 wt% hydrogen covalently bound to the carbon.
Patent WO-2021025869-A1 (WO)
Inventor: DAVIS STEPHEN RICHARD
IPC: A01K1/04
Filed: 2020-07-23
Abstract: The present disclosure is directed to a flexible, adjustable, collar. The collar includes a flexible member having a first end and a second end. A plurality of surface features, each having a raised portion on the upper surface the flexible member and a corresponding recessed portion on the lower surface of the flexible member, extend from the first end along the longitudinal axis of the flexible member. An attachment channel to accommodate the passage of the first end of the flexible member is disposed proximate the second end of the flexible member. An attachment feature having a physical geometry corresponding to the recessed portion of the surface feature is disposed on the bottom portion of the attachment channel. As the first end of the flexible member is passed through the attachment channel, the attachment feature engages the recessed portion of each of the surface features.
Patent WO-2021016585-A1 (WO)
Title: Chimeric antigen receptors with mage-a4 specificity and uses thereof
Inventor: BRAY KEVIN
IPC: A61K39/00
Filed: 2020-07-24
Abstract: MAGE-A4, or Melanoma-Associated Antigen A4, is a cancer-testis antigen (CTA) on the X chromosome. The present disclosure provides MAGE-A4-specific chimeric antigen receptors and cells expressing such chimeric antigen receptors. In certain embodiments, engineered cells expressing the chimeric antigen receptors of the present disclosure are capable of inhibiting the growth of tumors expressing MAGE-A4. The engineered cells of the present disclosure are useful for the treatment of diseases and disorders in which an upregulated or induced MAGE-A4-targeted immune response is desired and/or therapeutically beneficial. For example, engineered cells expressing the MAGE-A4-specific chimeric antigen receptors of the present disclosure are useful for the treatment of various cancers.
Patent WO-2021021863-A1 (WO)
Title: Empilements d'encapsulation multicouches par dépôt de couche atomique
Inventor: TRINH CONG
IPC: H01L45/00
Filed: 2020-07-29
Abstract: L'invention concerne des procédés de dépôt d'un empilement d'encapsulation sans endommagement de couches sous-jacentes. Les empilements d'encapsulation sont hautement conformes, ont de faibles vitesses de gravure, de faibles concentrations en oxygène atomique, une bonne herméticité et une bonne adhérence. Ces films peuvent être utilisés pour protéger des matériaux chalcogènes dans des dispositifs PCRAM. Certains modes de réalisation utilisent un procédé en deux étapes comprenant un premier procédé ALD pour former une couche protectrice et un second procédé ALD au plasma pour former une couche d'encapsulation.
Patent WO-2021021898-A1 (WO)
Inventor: HEGGE ROBERTUS F
IPC: G01V1/36
Filed: 2020-07-29
Abstract: Systems and methods include a method for deblending signal and noise data. A shot domain for actual sources, a receiver domain for virtual sources, and a receiver domain for actual sources are generated from blended shot data. A dictionary of signal atoms is generated. Each signal atom includes a small patch of seismic signal data gathered during a small time window using multiple neighboring traces. A dictionary of noise atoms is generated. Each noise atom includes a small patch of seismic noise data gathered during a small time window using multiple neighboring traces. A combined signal-and-noise dictionary is generated that contains the signal atoms and the noise atoms. A sparse reconstruction of receiver domain data is created from the combined signal-and-noise dictionary. The sparse reconstruction is split into deblended data and blending noise data based on atom usage to create deblended shot domain gathers for actual sources.
Patent WO-2021030097-A1 (WO)
Title: Glass manufacturing apparatus and methods
Inventor: AMOSOV ALEXEY SERGEYEVICH
IPC: C03B17/06
Filed: 2020-08-04
Abstract: Glass manufacturing apparatus can comprise a forming device comprising a pipe. The pipe can comprise a pipe wall defining a flow passage and a slot extending through the pipe wall. Glass manufacturing apparatus can further comprise a thermal control device defining a thermal control path. A projection of the thermal control path can intersect a footprint circumscribed by an outer periphery of the slot. Methods of manufacturing glass can comprise flowing molten material along a flow direction of the flow passage. Methods can also comprise flowing the molten material through the footprint of the slot. Methods can further comprise operating a thermal control device defining a thermal control path. A projection of the thermal control path can intersect the footprint. Methods can additionally comprise adjusting a temperature of the molten material at a location where the thermal control path intersects the molten material.
Patent WO-2021035116-A1 (WO)
Title: Hierarchical memory systems
Inventor: Korzh Anton
IPC: G06F13/24
Filed: 2020-08-21
Abstract: Apparatuses, systems, and methods corresponding to hierarchical memory systems are described. Logic circuitry can be resident on a persistent memory device, thereby reducing latencies associated with transferring data between the logic circuitry and the persistent memory device. Logic circuitry on a persistent memory device may include an address register configured to store logical addresses corresponding to stored data. The logic circuitry may receive a redirected request (e.g., prior to redirection, directed to a non-persistent memory device) to retrieve a portion of the data stored in the persistent memory device, determine, in response to receipt of the request to retrieve the portion of the stored data, a physical address corresponding to the portion of the data based on the logical address stored in the address register, and cause the data to be retrieved from the persistent memory device.
Patent WO-2022046079-A1 (WO)
Title: Barriers in microfluidic channels
Inventor: SASSER JACOB SHANE
IPC: G01N33/48
Filed: 2020-08-28
Abstract: In one example in accordance with the present disclosure, a fluid manipulation system is described. The fluid manipulation system includes a microfluidic channel through which fluid is to flow. The fluid includes biomolecules to be separated. The fluid manipulation system also includes at least one array of biomolecule-capturing pillars disposed within the microfluidic channel to capture biomolecules from the fluid. Barriers rise from a surface of the microfluidic channel. The barriers span a width of the microfluidic channel orthogonal to a flow of the fluid to induce vortices in the fluid flow.
Patent WO-2021071622-A1 (WO)
Inventor: WALL FRANKLIN
IPC: G02B6/42
Filed: 2020-09-11
Abstract: L'invention concerne un émetteur-récepteur optique ayant un ensemble de verrouillage qui empêche un mouvement indésirable de l'émetteur-récepteur optique lorsqu'il est en prise avec un autre dispositif. L'ensemble de verrouillage comprend une glissière avec une saillie, un dispositif de levage et des butées pondérées. Dans une première configuration, la glissière et les butées pondérées peuvent maintenir un contact entre un matériau d'interface thermique de l'émetteur-récepteur optique et l'autre dispositif tout en bloquant l'émetteur-récepteur optique pour empêcher le mouvement. Dans un second mode de configuration, l'ensemble de verrouillage enlève le matériau d'interface thermique de l'autre dispositif et déverrouille les butées pondérées pour permettre la déconnexion de l'autre dispositif.
Patent WO-2021067257-A1 (WO)
Title: Agriculture service platform
Inventor: ZIMMERS GREG
IPC: G06F3/048
Filed: 2020-09-29
Abstract: A system, method, and operating environment facilitate providing year-round agriculture management services to a grower. The method may include determining a geographic location of a field associated with a grower; obtaining information representative of an event prediction, such as a weather forecast, corresponding to the geographic location from one or more information sources; obtaining grower data associated with the grower; predicting an agronomic consequence based on the event prediction and the grower data; and providing a notification of the event prediction to the grower.
Patent WO-2021080883-A1 (WO)
Inventor: RAMANI KRISHNAN V
IPC: G06F9/38
Filed: 2020-10-18
Abstract: Selon la présente invention, une exécution spéculative à l'aide d'une file d'attente d'ordres de charge à suivi par niveau de page comprend : le fait de déterminer qu'une première instruction de charge vise une région de mémoire déterminée ; et, en réponse au fait que la première instruction de charge vise la région de mémoire déterminée, l'ajout d'une entrée à une file d'attente d'ordres de charge à suivi par niveau de page au lieu d'une file d'attente d'ordres de charge, l'entrée indiquant une adresse de page d'une cible de la première instruction de charge.
Patent WO-2021086870-A1 (WO)
Title: Systems and methods for predicting and providing automated online chat assistance
Inventor: KUO YU-HSUAN
IPC: G06N20/00
Filed: 2020-10-27
Abstract: Methods and systems are presented for providing automated online chat assistance in an online chat session. One or more utterances transmitted from a user device of a user via the online chat session are obtained. The one or more utterances are provided to a first prediction model to predict an intent of a user. If it is determined that the first prediction model is unable to predict the intent of the user based on the one or more utterances, the one or more utterances are provided to a second prediction model. After predicting the intent of the user by the second prediction model, the intent is used by a chat robot to provide a dialogue with the user via the online chat session. The one or more utterances and the predicted intent are used to re-train the first prediction model.
Patent WO-2021119123-A1 (WO)
Inventor: THOMAS SYMON
IPC: C02F1/00
Filed: 2020-12-09
Abstract: A filter system is provided that comprises a first filter element in fluid communication with a source of a fluid, wherein the fluid flows through the first filter element and a second filter element in fluid communication with the first filter element, wherein the fluid, flowing through the first filter element flows through the second filter element and is discharged. The first filter element comprises a material adapted to stop the passage of materials greater than a selected size. The second filter element is adapted to remove an organic substance from the liquid.
Patent WO-2021127046-A1 (WO)
Title: Combinations
Inventor: SAMATAR AHMED
IPC: A61K31/437
Filed: 2020-12-16
Abstract: Disclosed herein are combinations of compounds for treating a disease or condition, such as cancer. A combination of compounds for treating a disease or condition can include a SERD inhibitor and a WEE1 inhibitor, along with pharmaceutically acceptable salts of any of the foregoing.
Patent WO-2022132148-A1 (WO)
Title: Optical fiber cable structure having rollable ribbon units and an elastomeric layer
Inventor: DEBBAN HAROLD
IPC: G02B6/48
Filed: 2020-12-17
Abstract: Embodiments of the invention include an optical fiber cable. The optical fiber cable includes a multi-fiber unit tube that is substantially circular and dimensioned to receive a plurality of optical fibers. The optical fiber cable also includes a plurality of partially bonded optical fiber ribbon units positioned within the multi-fiber tube. The partially bonded optical fiber ribbon units are partially bonded in such a way that each partially bonded optical fiber ribbon is formed in a substantially circular shape or a random shape. The optical fiber cable also includes at least one elastomeric strength layer formed around the partially bonded optical fiber ribbon units. The optical fiber cable also includes an outer jacket surrounding the multi-fiber tube.
Patent WO-2021138292-A1 (WO)
Title: Battery separator configured for reducing acid stratification for enhanced flooded batteries
Inventor: BRILMYER GEORGE
IPC: H01M10/06
Filed: 2020-12-29
Abstract: A battery separator configured for reducing acid stratification for an enhanced flooded battery. The battery separator for the enhanced flooded battery is configured to minimize acid stratification. The battery separator is comprised of a microporous membrane and an absorptive mat. The absorptive mat includes a 3-hour wicking height greater than 15cm. Wherein the absorptive mat of the battery separator is configured to minimize acid stratification of the enhanced flooded battery.
Patent WO-2021108797-A1 (WO)
Title: Circuit de minuterie à flottement autonome de broches et systèmes, procédés et dispositifs associés
Inventor: LASSEN JACOB LUNN
IPC: H03K19/00
Filed: 2020-06-04
Abstract: L'invention concerne un système électrique comprenant un dispositif à circuit intégré comprenant des broches d'entrée/sortie (E/S), un circuit de réinitialisation et un circuit d'E/S. Le circuit d'E/S est couplé de manière fonctionnelle aux broches d'E/S. Le circuit d'E/S est configuré pour faire fonctionner sélectivement les broches d'E/S dans un état électriquement flottant en réponse à un signal de réinitialisation de système transmis par le circuit de réinitialisation. Le circuit d'E/S est en outre configuré pour faire fonctionner sélectivement les broches d'E/S dans l'état électriquement flottant en réponse à un signal fourni par un circuit de minuterie indépendamment du circuit de réinitialisation.
Patent WO-2021262244-A1 (WO)
Title: Mobile device having multiple corresponding sensors
Inventor: XU YURONG
IPC: G06F1/3287
Filed: 2020-06-22
Abstract: A mobile device such as a smart phone, tablet computer, Internet of things (loT) device, and/or wearable device includes a sensor module (230) coupled to multiple corresponding sensors (302, 432, 304, 434, 306, 436). The multiple corresponding sensors include multiple instances of the same type of motion sensor in different physical locations on the mobile device. The sensor module includes a software architecture/algorithm that can configure the multiple corresponding sensors to provide sensor measurements having a higher sampling frequency and/or an improved accuracy. In addition, the sensor module may provide sensor measurements having additional degrees of freedom and/or lower power consumption than can be provided by existing sensor modules. In one example, the multiple corresponding sensors include multiple accelerometers that operate at relatively low power to provide linear acceleration samples the sensor module processes the multiple linear acceleration samples to generate a measure of angular acceleration used to activate the mobile device.
Patent WO-2021042127-A1 (WO)
Inventor: LEE MARTIN
IPC: A61Q5/00
Filed: 2020-08-28
Abstract: A packaged hair care composition comprising a first composition and a second composition, wherein the first and second compositions are kept in separate packaging chambers until dispensed. The first composition comprises a cationic polymer; and an aqueous carrier and has a G' value of about 160 to about 410; and the second composition comprises: a cationic surfactant; a high melting point fatty compound; and an aqueous carrier and has a G' value of from about 600 Pa to about 3000 Pa. The package comprises an outer tube body having an exterior layer and an outer tube interior chamber; and an inner tube having an exterior layer and an inner tube body having an inner tube interior chamber; a dispensing orifice wherein a portion of the dispensing orifice is in communication with the outer tube interior chamber, and a portion of the dispensing orifice is in communication with the inner tube interior chamber.
Patent WO-2021119644-A1 (WO)
Inventor: ZHOU YAN
IPC: H04L1/00
Filed: 2020-10-13
Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive downlink control information (DCI) that includes a downlink and/or uplink beam activation command or a reference signal activation command. The UE may apply the downlink and/or uplink beam activation command or the reference signal activation command included in the DCI according to an action time that is based at least in part on a quantity of symbols after an event related to reception of the DCI. Numerous other aspects are provided.
Patent WO-2021150681-A1 (WO)
Title: Wellbore conditioning with a reamer on a wireline
Inventor: AL-GHAMDI MUATAZ S
IPC: E21B49/08
Filed: 2021-01-21
Abstract: To condition a wellbore with a reamer on a wireline, a portion of a wellbore is formed from a surface of the earth toward a subsurface hydrocarbon reservoir using a wellbore drilling assembly. After forming the portion of the wellbore, the wellbore drilling assembly is removed from the portion of the wellbore. Using a wireline, a wellbore sampling tool and a reamer are lowered into the portion of the wellbore. While maintaining the wellbore sampling tool and the wireline in a non-rotational state, the portion of the wellbore is cleaned using the reamer.
Patent WO-2021151051-A1 (WO)
Title: Method and article of manufacture of cutter for pdc cutting system
Inventor: MAHAFFEY JR
IPC: E21B7/04
Filed: 2021-01-25
Abstract: Material removal systems including milling drum and milling-drumless products, systems, manufactures, and methods for removing material, such as concrete or asphalt, or industrial flowing applications may be augmented with manufactures that provide one or more of an alignment feature for controlling orientation of abrasive elements and manufactures that provide destructive interference and durability of abrasive elements during operation. Manufactures and methods of fabricating manufactures are provided. The method allows configurations of matched pairs of individual abrasive elements to be easily made to a variety of applications in a parametric, semi-parametric, or non-parametric manner, and may provide one or more of an alignment feature for controlling orientation of abrasive elements and sinusoidal, near-sinusoidal or non-sinusoidal destructive interference effects, while providing durability of abrasive elements during operation.
Patent WO-2021154947-A1 (WO)
Title: Peptide immunogens targeting pcsk9 and formulations thereof for prevention and treatment of pcsk9-mediated disorders
Inventor: WANG CHANG YI
IPC: C07K19/00
Filed: 2021-01-28
Abstract: The present disclosure is directed to peptide immunogen constructs targeting the catalytic domain of the PCSK9 protein, compositions containing the constructs, antibodies elicited by the constructs, and methods for making and using the constructs and compositions thereof. The disclosed peptide immunogen constructs have more than about 20 amino acids and contain (a) a B cell epitope having about more than about 7 contiguous amino acid residues from the PCSK9 and LDL-R receptor binding regions of the catalytic domain of the PCSK9 protein; (b) a heterologous Th epitope; and (c) an optional heterologous spacer. The disclosed PCSK9 peptide immunogen constructs stimulate the generation of highly specific antibodies directed to PCSK9 sites that are binding to LDL-R to allow for the prevention and/or treatment of patients with PCSK9 mediated disorders including an increased serum level of low-density lipoprotein cholesterol (LDL-C) and CV events.
Patent WO-2021188810-A1 (WO)
Title: Constraints on reference picture lists for subpictures
Inventor: WANG YE-KUI
IPC: H04N13/00
Filed: 2021-03-18
Abstract: Methods and apparatus for processing of video are described. The processing may include video encoding, decoding or transcoding. One example video processing method includes performing a conversion between a video comprising a current picture comprising a current subpicture comprising a current slice and a bitstream of the video, wherein the bitstream conforms to a format rule that disallows an active entry in a reference picture list of the current slice from including a first picture that precedes in a decoding order a second picture that includes a step-wise temporal sublayer access subpicture in response to conditions associated with at least the first picture and the current subpicture.
Patent WO-2021195150-A1 (WO)
Inventor: HUNT MACKENZIE
IPC: C12Q1/70
Filed: 2021-03-23
Abstract: A stand-alone molecular diagnostic test device includes a housing, a reverse transcription module, an amplification module, and a detection module. The reverse transcription module is configured to heat a biological sample to produce a target cDNA molecule associated with an RNA virus thereby producing an amplification solution. The amplification module defines a reaction volume configured to receive the amplification solution and amplify the target cDNA molecule within the amplification solution to produce an output. The detection module is configured to receive the output from the amplification module and includes one or more probes specific to a polynucleotide sequence of the RNA virus. The one or more probes is designed to facilitate production of a signal indicating the presence of the RNA virus in the biological sample.