baber/WOPTO huggingface dataset:
Patent DE-69110592-T2 (DE)
Inventor: PHADKE DEEPAK S
IPC: A61K9/46
Filed: 1991-09-20
Granted: 1995-12-21
Abstract: The present invention is directed towards a superior tasting pharmaceutical composition having porous granules produced through in situ gas generation using effervescence-producing ingredients and a process for producing the same. The method disclosed herein is especially suitable for producing superior tasting antacid tablets as well as superior tasting calcium supplements.
Patent DE-69120546-T2 (DE)
Inventor: OLIVE PETER
IPC: A61M5/142
Filed: 1991-11-22
Granted: 1996-10-31
Abstract: A flow regulator/restrictor placed in a fluid path to passively compensate for variations in fluid pressure by deflection or movement. In one embodiment a silicon micromachined housing has a damper beam cantilevered to the interior wall between inlet and outlet. Deflections of the beam vary the volume of the restrictive gap formed between the damper beam and the interanl wall of the housing adjacent the outlet. In another embodiment the damper element is a floating element in the housing and has conformal side walls with the interior of the housing. The restrictor elements may be stacked to provide a stepped pressure drop, restrictor system.
Patent DE-69122853-T2 (DE)
Inventor: LUNDQUIST INGEMAR
IPC: A61B1/00
Filed: 1991-01-31
Granted: 1997-10-09
Abstract: A steering mechanism (315) including a steering shaft (320) coupled to a controller (410) which includes a handle (540) and apparatus for manipulating the distal end (340) of the steering shaft. The steering shaft includes a flexible coiled spring (170) having a lead spring (350) fixed in position with respect to a distal end thereof in the distal end of the steering shaft. One or more steering wires (360, 370) is affixed at the distal ends thereof to the lead spring. The steering wires extend through the steering shaft to the controller, and the steering apparatus of the controller is used to place tension on one or both of the steering wires. The attachment of the distal ends of the steering wires to the lead spring may be opposite one another or may be offset for providing greater maneuverability. Tension may be placed on the steering wires by wedges (650, 660) mounted transversely to the controller housing, or by rotation of a shaft (450) mounted transversely to the controller housing, the steering wires being attached to the shaft such that rotation in one direction tenses one steering wire, and rotation in the other direction tenses the other steering wire. Two independently rotatable shafts (1560, 1590) may be used to separately control the two steering wires. The steering shaft is adapted for insertion into a lumen (45) of a catheter (40) for use in guiding the distal end of the catheter to a treatment site within a patient. The steering mechanism may also be used in conjunction with tools or apparatus which must reach into difficult locations, such as engines or other machines.
Patent DE-69132725-T2 (DE)
Inventor: KNAUF C
IPC: C07K14/415
Filed: 1991-03-14
Granted: 2002-07-11
Abstract: Novel DNA constructs which may be used as molecular probes or inserted into a plant host are provided. These constructs comprise a sequence obtainable from the Bce4 gene that is capable of directing transcription in seed tissue at least as early as 11 days after anthesis until approximately 30-35 days after anthesis, joined to a nucleic acid sequence of interest, and a transcription termination region. Thus, transcription of a message encoded by a nucleic acid sequence under the control of the Bce4 regulatory region will occur at a specific time of seed development. In this manner, production of exogenous products, as well as modulation of endogenous products, may be achieved.
Patent DE-69202923-T2 (DE)
Inventor: DELMAS FRANCOIS
IPC: C01D3/16
Filed: 1992-06-02
Granted: 1996-02-15
Abstract: The present invention is a process for purifying an aqueous alkali metal chloride solution containing iodine essentially in the iodide form, in which the iodine is oxidised to an oxidation number of 7, that is to say in the periodate form, and then the periodate is removed. Simultaneously, the ammonium is also destroyed by oxidation to molecular nitrogen followed by a degassing.
Patent DE-69206837-T2 (DE)
Inventor: BOUGAMONT JEAN-LOUIS
IPC: B05B15/30
Filed: 1992-02-12
Granted: 1996-08-08
Abstract: The subject of the invention is a package for viscous products, consisting of a container comprising a cylindrical jacket (11) surmounted by a socket (12) contained in which is a well (13) to which belongs a tube (12b), the intake of which is at its distal end and carries a dispenser (17, 18), and an inverted movable base formed by an annular plunger (16) which drives out the product as it is used. This package is stable and well sealed, can be used for the sale of various products, especially household, cosmetic or pharmaceutical products, and is easy to assemble and to fill. <IMAGE>
Patent DE-69208636-T2 (DE)
Inventor: RADATUS BRUNO
IPC: C07H19/06
Filed: 1992-06-22
Granted: 1996-07-11
Abstract: A composition of a 1:1 molar complex of guanidine and 3'-azido-3'-deoxythymidine (AZT) which is generated at about pH above 9 and disrupted by pH below about 9. This complex is a useful intermediate in the purification of AZT.
Patent DE-69212312-T2 (DE)
Inventor: ABERG BO-CHRISTER
IPC: D21F3/02
Filed: 1992-05-22
Granted: 1997-02-06
Abstract: PCT No. PCT/SE92/00344 Sec. 371 Date Nov. 18, 1993 Sec. 102(e) Date Nov. 18, 1993 PCT Filed May 22, 1992 PCT Pub. No. WO92/20858 PCT Pub. Date Nov. 26, 1992.A press is devised for a papermaking machine. The press is of the type having a rotary press roll, a substantially stationary pressure shoe, and a press belt running in an endless path around the pressure shoe between this and the press roll and having a substantially impermeable inner surface facing the pressure shoe. A separate, endless reinforcing belt enclosing the press belt is in frictional engagement over the entire length of the press belt so as to run together in the press belt in the endless path. The reinforcing belt may be prestressed, e.g. by shrinkage, in its running direction and, optionally, also transversally thereof. According to a second aspect, the invention relates to a method of modifying a press of the type indicated above, in which method the press belt is enclosed by a separate, endless reinforcing belt of the above-indicated type.
Patent DE-69212713-T2 (DE)
Inventor: BATTISTEL EZIO ANGELO
IPC: C12N9/02
Filed: 1992-06-03
Granted: 1997-03-06
Abstract: Described is a process for the enzymatic production of cephalosporane derivatives, or their salts, having the formula (I): <CHEM> wherein R represents a -CO-COOH or -COOH group and R' is H, OH or -O-CO-R'', R'' being a C1-C4 alkyl group, including the oxidative deamination of compounds, or their salts, having the formula (II): <CHEM> in the presence of a micro-organism of the Rhodotorula type or D-aminoacid oxidase derived therefrom, in free or immobilized form.
Patent DE-69215110-T2 (DE)
Inventor: BACKLUND AKE
IPC: D21C3/24
Filed: 1992-08-11
Granted: 1997-04-03
Abstract: A process for the continuous digestion of cellulosic fiber material, comprising impregnation with impregnating liquid consisting of at least one fresh digesting liquor, in a closed impregnating system and subsequent digestion with digesting liquid in a closed digester system, said impregnating liquid being supplied through a supply system, together with steamed fibre material, to an inlet end of the impregnating system, liquid being withdrawn from the impregnating system at a point (46) located at a predetermined distance from said inlet end. According to the invention such a first quantity of liquid (F) is withdrawn at said withdrawal point (46) and recirculated directly to the supply system that a predetermined minimum ratio between liquid and fibre material is continuously maintained in the impregnating system prior to said withdrawal point (46), the liquid in said liquid to fibre material ratio being derived from original moisture (A) in the fibre material, condensates (B, C) from an initial steaming of the fibre material, and added fresh digesting liquor(s) (D and/or E) besides said withdrawn and recirculated quantity of liquid (F).
Patent DE-69219470-T2 (DE)
Inventor: MILLER BRUCE
IPC: A61K31/765
Filed: 1992-06-19
Granted: 1997-11-06
Abstract: Multiple daily applications of a topical composition having as the active ingredients an anesthetic and a surfactant with antiviral activity decrease the time of healing of herpes simplex viral lesions from approximately ten to fourteen days to three to five days, as well as decrease inflammation and pain. The composition is applied to the lesions daily, approximately every four hours, preferably beginning at the preliminary or prodromal stage of infection. Relief is almost immediate, and is characterized by decreased pain, swelling, and more rapid healing as compared with the untreated lesion.
Patent DE-69226631-T2 (DE)
Inventor: MARKS GEOFFREY
IPC: C09D183/00
Filed: 1992-02-26
Granted: 1998-12-24
Abstract: An aqueous composition for the treatment of surfaces such as metals particularly aluminium, comprises a tetraalkyl silicate or a monomeric or oligomeric hydrolysis product thereof, and an inorganic passenger powder below 100 nm diameter such as fumed silica, both in dispersion in a fluid aqueous medium. The composition can be applied as a conversion coating to improve the adhesion of subsequently applied paint, lacquer or adhesive. Non-aqueous intermediate products comprising the silicate component and passenger powder can be diluted with water to make the coating composition.
Patent DE-69228378-T2 (DE)
Inventor: SCHUELEIN MARTIN
IPC: A23K20/189
Filed: 1992-03-27
Granted: 1999-08-26
Abstract: The xylanase is characterized by several partial amino acid sequences and is immunoreactive with an antibody raised against a purified xylanase derived from Humicola insolens, DSM 1800. This xylanase preparation is practically free of cellulase and is well suited for treatment of paper pulp, as a baking agent and as an additive to fodder.
Patent DE-69231582-T2 (DE)
Inventor: SARABHAI ANAND
IPC: A23L11/00
Filed: 1992-03-11
Granted: 2001-06-28
Abstract: A non-wheat containing pasta product prepared from urad legumes. Optionally, other legumes and/or non-wheat cereal grains may be combined with the urad legumes.
Patent DE-69233327-T2 (DE)
Inventor: OSHLACK BENJAMIN
IPC: A61K47/44
Filed: 1992-11-25
Granted: 2005-03-10
Abstract: (A) Controlled release oxycodone formulation for oral admin. to human patients, comprises (i) 10-40mg oxycodone or its salt, the formulation providing a mean max. plasma conc. of oxycodone of 6-60 ng/ml from a mean of 2-4.5 hrs.. After admin., and a mean min. plasma conc. of 3-30 ng/ml from a mean of 10-14 hrs. after repeated admin. every 12 hrs. through steady state conditions. (ii) 10-160 mg oxycodone or its salt, the formulation providing a mean max. plasma conc. of oxycodone of 6-240 ng/ml from a mean of 2-4.5 hrs. after admin., and a mean min. plasma conc. from 3-120 ng/ml from a mean of 10-14 hrs. after repeated admin. every 12 hrs. through steady-state conditions. (B) Also claimed is a solid controlled release oral dosage form comprising (i) oxycodone or its salt in amt. of 10-160 mg; a controlled release matrix selected from hydrophilic hydrophobic polymers, digestible opt. substd. 8-50C hydrocarbons, and/or polyalkylene glycols; and a diluent; wherein the compsn. provides a mean max. plasma conc. of oxycodone of 6-240 ng/ml from a mean of 2-4.5 hrs. after admin, and mean min. plasma conc. of 3-120 ng/ml from a mean of 10-14 hrs. after repeated admin. every 12 hrs. through steady-state conditions; or (ii) an analgesically effective amt. of spheroids comprising oxycodone or its salt and either a spheronising agent or an acrylic polymer or copolymer, such that the total dosage of oxycodone in the dosage form is 10-160 mg; a film coating which controls the release of the oxycodone or its salt at a controlled rate in an aq. medium, wherein the compsn. provides an in vitro dissolution rate of the dosage form.
Patent DE-69300373-T2 (DE)
Inventor: KOSLEY RAYMOND W
IPC: C07D209/30
Filed: 1993-03-31
Granted: 1996-02-29
Abstract: There are disclosed compounds having the formula <CHEM>  wherein   X   is hydrogen, chloro, bromo, fluoro, hydroxy, loweralkoxy, arylloweralkoxy, acyloxy, loweralkylaminocarbonyloxy, diloweralkylaminocarbonyloxy, amino, loweralkylamino, diloweralkylamino, acylamino, loweralkyl or trifluoromethyl; Y   is hydrogen, loweralkyl, chloro or bromo; Z   is hydrogen, loweralkyl, loweralkoxy or halogen; or X and Z taken together can form a methylenedioxy group; R<1>   is hydrogen, loweralkyl, arylloweralkyl, carboxyloweralkyl, arylloweralkoxycarbonylloweralkyl or loweralkoxycarbonylloweralkyl; R<2>   is hydrogen, loweralkyl or hydroxyloweralkyl; R<3>   is hydrogen or loweralkyl; or R<2> and R<3>   together with the carbon to which they are attached form (C3 - C7)cycloalkyl; R<4>   is hydrogen or loweralkyl; R<5>   is hydrogen, loweralkyl, aryl, arylloweralkyl, acyl, arylloweralkoxycarbonyl, loweralkoxycarbonyl or aryloxycarbonyl; R<6>   is hydrogen, chloro, bromo, arylcarbonyl, loweralkylcarbonyl, aryl(hydroxy)loweralkyl or hydroxyloweralkyl; and m and n   are independently 0 to 5 with the proviso that the sum of m plus n is not greater than 5; and pharmaceutically acceptable addition salts thereof, or where applicable, the optical or geometrical isomers or racemic mixtures thereof, intermediates in the process for making the compounds, a process for making the compounds and pharmaceutical compositions and their use as neuroprotective agents.
Patent DE-69301792-T2 (DE)
Inventor: DALBON GERARDO
IPC: A21C1/00
Filed: 1993-08-03
Granted: 1996-09-26
Abstract: A process for preparing a dough for "pasta", by starting from meals of cereals in general, which dough is to be sent to an extrusion screw, which process comprises:   (1) a step of separation of raw material into at least two fractions having different granulometries, each defined within a granulometric range; (2) a step of checking the percent amounts of said fractions with different granulometry, by measuring the weight of each of said fractions, by means of a suitable device; (3) a step of metering the above said fractions and of metering water for each of said fractions, in a variable ratio, by means of a first metering device for the solid phase and a second metering device for the liquid phase; (4) a different kneading step different for each granulometric fraction.   A device for implementing such a process is furthermore disclosed. One of the advantages displayed by the present invention consists in the decrease in the amount of sugars deriving from physical-chemical reactions induced during the kneading step. Furthermore, the present invention yields the possibility of fractionating the solid raw materials into "N" fractions, with N larger than, or equal to 2, with defined granulometric attributes. A further advantage consists in the possibility of matching the kneading time to each individual fraction with different granulometry. <IMAGE>
Patent DE-69311633-T2 (DE)
Inventor: WICKS DOUGLAS A
IPC: C09D175/02
Filed: 1993-05-28
Granted: 1997-10-16
Abstract: The present invention relates to a coating composition for the preparation of a polyurea coating which contains     a) a polyisocyanate component,   b) at least one compound corresponding to the formula <CHEM>  wherein   X   represents an organic group which has a valency of n and is inert towards isocyanate groups at a temperature of 100 DEG C or less, R<1> and R<2>   may be identical or different and represent organic groups which are inert towards isocyanate groups at a temperature of 100 DEG C or less, R<3> and R<4>   may be identical or different and represent hydrogen or organic groups which are inert towards isocyanate groups at a temperature of 100 DEG C or less and n   represents an integer with a value of at least 2, and   c) 0.001 to 5 weight percent, based on the weight of components a) and b), of a tin(IV) compound which is a catalyst for the reaction between isocyanate groups and hydroxyl groups.
Patent DE-69312768-T2 (DE)
Inventor: VERHOOF JEROEN WALTHERUS
IPC: G01M11/00
Filed: 1993-03-01
Granted: 1998-01-08
Abstract: Method for determining fault locations in a local optical network. In the case of a fibre failure arising, a measuring signal is fed to the network, the reaction of the network to said measuring signal being analysed and converted into a location indication of said fibre failure. The output signal of the optical light source, in addition to the normal signal, is also modulated by the measuring signal. The measuring signal is preferably an OFDR signal, a signal having a frequency which varies according to a defined pattern. The signal reflected at the location of the fibre failure is converted into an electrical reflection signal. Said reflection signal is compared with the original measuring signal and, by means of frequency analysis of the two signals, the location of the fibre failure is calculated. <IMAGE>
Patent DE-69322396-T2 (DE)
Inventor: DOPPER JAN HENDRIK
IPC: A61K9/16
Filed: 1993-12-10
Granted: 1999-07-29
Abstract: Disclosed is a process of preparing granules involving first preparing a carrier comprising diluent, binder, and optionally a disintegrating agent. In a container separate from said carrier, a steroid, lubricant and, optionally, an antioxidant are dissolved in an, optionally pre-heated, organic solvent. The resulting solution is added to the carrier contained within an, e.g vacuum mixer, followed by further blending of the mixture. The organic solvent is removed from the mixture. The mixture is blended further to form granules. The process may further include incorporating a flow enhancer such as colloidal silicon dioxide into the granules. A granule for making a pharmaceutical dosage unit is granule characterized in comprising: a) a carrier comprising diluent and binder, and b) a film coating said carrier, said film comprising desogestrel and a lubricant, and has the characteristic of by retaining 90% of the desogestrel at a pressure of 150 mbar and at a temperature of 70 DEG  C over 72 hours.
Patent DE-69329712-T2 (DE)
Inventor: HORWELL DAVID CHRISTOPHER
IPC: A61P35/00
Filed: 1993-08-12
Granted: 2001-04-12
Abstract: The invention concerns tachykinin antagonists. The compounds are nonpeptides which have utility in treating disorders mediated by tachykinins. Such disorders are respiratory, inflammatory, gastrointestinal, ophthalmic, allergies, pain, vascular, diseases of the central nervous system, and migraine. Methods of preparing compounds and novel intermediates are also included. <??>The compounds are expected to be especially useful in asthma and rheumatoid arthritis.
Patent DE-69330165-T2 (DE)
Inventor: MOITEIRO MARIA
IPC: C07J63/00
Filed: 1993-10-07
Granted: 2001-08-30
Abstract: The new triterpenoids of general formulae (I), (II), (III) and (IV) where R<1> represents a dialkyl, trialkyl, triphenyl, diphenylalkyl, alkyldiphenyl, dialkylphenyl, haloalkyl, halophenylalkyl, allylalkyl or alkylaminoalkyl group and R<2> represents a carboxyl group, salt or ester, and a process for their preparation which comprises reaction of friedelin with a silylating agent in the presence of a bulky strong base, with kinetic or thermodynamic control, to produce regio-specifically compounds of general formula (I) or (II). Oxidation of (I) or (II) yields the corresponding hydroxy ketones (VII) or (VIII), from which acyl and glycosyl derivatives can be prepared, and further oxidation of the hydroxy ketones (VII) or (VIII) with peracid gives the seco-aldehyde acids (III) or (IV), from which esters or salts can be prepared. Ozonolysis of (I) or (II), followed by reductive treatment, produces the diols of formula (IX) or (X), from which acyl and glycosyl derivatives can be prepared. Oxidation of (I) with a benzoquinone leads to friedel-1-en-2-one (XI) in high yields. Compounds or combinations of compounds (I), (II), (III), (IV), (VI), (VII), (VIII), (IX), (X), (XII), including the acyl and glycosyl derivatives thereof, find application in fungicidal, bactericidal, antitumour and antifeedant compositions.
Patent DE-69330945-T2 (DE)
Inventor: FIELD RAYMOND PAUL
IPC: C12N5/071
Filed: 1993-07-26
Granted: 2002-06-20
Abstract: An animal cell culture medium is described which contains 2-hydroxy-2,4,6-cycloheptatrien-1-one or a derivative thereof to support the growth of animal cells, particularly in agitated cell culture at low iron concentrations.
Patent DE-69400772-T2 (DE)
Inventor: ABONDANCE ROGER
IPC: A63C5/12
Filed: 1994-04-13
Granted: 1997-03-20
Abstract: This ski comprises longitudinal reinforcing elements (7) which, each bearing on an edge (6) and forming the side walls of the ski, serve for supporting and fastening the sides of the shell (8), the height of the reinforcing elements (7) being substantially equal, in at least one zone of the ski, to the height of the latter, whilst, in at least one other zone of the ski, the height of the reinforcing elements (7) is less than the height of the ski, and the shell (8) has at least one part (12) which slopes downwards and outwards. <IMAGE>
Patent DE-69401056-T2 (DE)
Inventor: BINLEY GARY NORMAN
IPC: A23G9/20
Filed: 1994-02-18
Granted: 1997-04-10
Abstract: Reproducible volumes of aerated material, e.g. ice confections, are disposed on a continuous basis by compressing a quantity to a predetermined volume and releasing the pressure before dispensing.
Patent DE-69401750-T2 (DE)
Inventor: PAPAKOSTOPOULOS DEMETRIUS
IPC: A61B3/06
Filed: 1994-04-26
Granted: 1997-08-21
Abstract: PCT No. PCT/GB94/00883 Sec. 371 Date Apr. 4, 1996 Sec. 102(e) Date Apr. 4, 1996 PCT Filed Apr. 26, 1994 PCT Pub. No. WO94/24926 PCT Pub. Date Nov. 10, 1994An apparatus is provided for collecting data. The apparatus is particularly, but not exclusively, applicable for the diagnosing of eye disorders. The apparatus contains a rack (1) having a plurality of engagement positions and a plurality of counters (5) for the rack (1), each counter (5) being engageable in any one of the engagement positions. Each counter (5) contains a specific, unique, electrical attribute which enables a detector included within the apparatus to detect and therefore process the data relating to the value of the electrical attribute of each counter (5).
Patent DE-69403119-T2 (DE)
Inventor: PEES KLAUS-JUERGEN
IPC: A01P3/00
Filed: 1994-03-02
Granted: 1997-08-28
Abstract: This invention relates to certain triazolopyrimidine derivatives of the general formula <CHEM> in which R<1> represents an optionally substituted alkyl, alkenyl, alkynyl, alkadienyl, cycloalkyl, bicycloalkyl or heterocyclyl group; R<2> represents a hydrogen atom or an alkyl group; or R<1> and R<2> together with the interjacent nitrogen atom represent an optionally substituted cycloalkyl or heterocyclic ring; R<3> represents an optionally substituted cycloalkyl or heterocyclyl group; and R<4> represents a hydrogen or halogen atom or a group -NR<5>R<6> where R<5> represents a hydrogen atom or an amino, alkyl, cycloalkyl or bicycloalkyl group and R<6> represents a hydrogen atom or an alkyl group; processes for their preparation; compositions containing such compounds and their use as fungicides.