baber/WOPTO huggingface dataset:
Patent CA-1307738-C (CA)
Inventor: CULLIS PIETER R
IPC: A61K9/127
Filed: 1987-06-15
Granted: 1992-09-22
Abstract: INDUCTION OF ASYMMETRY IN VESICLES                             ABSTRACT     Methods are described for controlling the transbilayer distribution of ionizable lipids and proteins in vesicles.  Control of the ion gradient of the exterior bathing medium in relation to that of the interior entrapped aqueous compartment of the vesicles induces migration of ionizable lipids or proteins to one or the other of the monolayers comprising the bilayer.  This can result in an asymmetric distribution of the ionizable lipid or ionizable protein.  The basic ionizable lipids, such as stearylamine and sphingosine, are sequestered into the inner monolayer when the liposome interior is acidic relative to the liposome exterior.  Conversely, acidic ionizable lipids such as oleic acid and stearic acid are sequestered into the inner monolayer when the liposome interior is basic relative to the liposome exterior bathing solution. Likewise, phospholipids such as phosphatidylglycerol, phosphatidylinositol, and cardiolipin may also be sequestered into the inner monolayer in response to a relatively acidic exterior medium. Such vesicles may contain bioactive agents and may be administered to mammals including humans.
Patent CA-1280125-C (CA)
Title: Zeolite rho and zk-5 catalysts for conversion of methanol and ammonia to dimethylamine
Inventor: ABRAMS LLOYD
IPC: C07C209/16
Filed: 1987-06-18
Granted: 1991-02-12
Abstract: TITLE            CONVERSION OF METHANOL AND AMMONIA TO DIMETHYLAMINE    ABSTRACT           Improved acidic zeolite rho and ZK-5 catalysts for conversion of methanol and ammonia to dimethylamine are disclosed.  The acidic zeolite rho catalyst is prepared by calcining zeolite NH4-rho or H-rho in the presence of steam.  The acidic zeolite ZK-5 catalyst is prepared by calcining zeolite NH4-ZK-5 or H-ZK-5 in the presence of steam.  An acidic zeolite rho which has been prepared by calcining zeolite NH4-rho in a vertical furnace in the presence of ammonia is disclosed.  Processes for producing dimethylamine with the specified catalysts are also disclosed.
Patent CA-1299192-C (CA)
Title: Method for production of 2-hydroxynaphthalene-6-carboxylic acid
Inventor: UENO RYUZO
IPC: C07C51/15
Filed: 1987-07-24
Granted: 1992-04-21
Abstract: Abstract The present invention is directed to a method of manufacturing 2-hydroxynaphthalene-6-carboxylic acid wherein .beta.-naphtholpotassium and carbon dioxide, in the presence of a reaction medium that substantially does not dissolve the .beta.-naphtholpotassium under heat and pressure, are reacted with the simultaneous transference of .beta.-naphthol produced and water existing in a reaction system to a vapor phase and elimination thereof from the reaction system.  The method of the present invention results in improved yields and selective ratio of the 2-hydroxynaphthalene-6-carboxylic acid.
Patent CA-1289937-C (CA)
Title: Perfluoropolyether solid fillers for lubricants
Inventor: JUHLKE TIMOTHY J
IPC: C10N40/00
Filed: 1987-08-06
Granted: 1991-10-01
Abstract: PERFLUOROPOLYETHER SOLID FILLERS FOR LUBRICANTS                 Abstract of the Disclosure Lubricants comprising perfluoropolyether oils containing perfluoropolyether solids as fillers are described.
Patent CA-1289520-C (CA)
Title: Keyboard support apparatus
Inventor: COTTERILL MICHAEL J
IPC: A47B21/03
Filed: 1987-09-03
Granted: 1991-09-24
Abstract: ABSTRACT         A keyboard support apparatus includes two substantially rigid parallel rods.  Each of the rods has a first respective bracket at one end.  Each rod is also slideably connected to a second respective bracket.  Also the rods are interconnected via keyboard mounting body which makes a slideable connection with each rod.  A manually operable screw fits into a threaded hole in the mounting body and may be adjusted to bear against one of the rods and thereby prevent the mounting body from sliding along the rods.  A keyboard or a keyboard shelf is mounted in front of the keyboard mounting body by means of a further structure which connects the underside of the keyboard or shelf to the underside of the mounting body.  When the support apparatus is screwed to the underside of the desk the keyboard may be slid under the desk or pulled out in front of the desk.  A preferred structure for mounting the keyboard onto the keyboard mounting body is also described.
Patent CA-1292738-C (CA)
Title: Aminopyrazinones and aminotriazinones
Inventor: BOEHNER BEAT
IPC: C07D239/47
Filed: 1987-09-24
Granted: 1991-12-03
Abstract: Aminopyrazinones and am;notriazinones Abstract Aminopyrazinones and aminotr;azinones of the formula I       (I) and the salts of these compounds with amines, alkali metal or alkaline earth metal bases or quaternary ammonium bases have good pre- and post-emergent selective herbicidal and growth-regulating properties.  In this formula, E is nitro-gen or =CR4-, R1 is C1-C4-alkyl, R2 is hydrogen, C1-C3-alkyl, C1-C3-halogenoalkyl, C1-C3-alkoxy, C1-C3-halogenoal-koxy, C1-C3-alkylthio, C1-C3-alkylsulfinyl, C1-C2-alkoxy-ethoxy, C1-C3-alkylsulfonyl, halogen or -NR5R6, R3 is hydro-gen or C1-C3-alkyl and Q is a group -?-NH-SO2-A, in which R4 is hydrogen, C1-C3-alkyl, C1-C3-halogenoalkyl, C1-C3-alkoxy, cyclopropyl, C1-C3-halogenoalkoxy, C1-C3-alkylthio, C2-C4-alkoxyalkyl, C3-C5-dialkoxymethyl, halogen or -NR5R6, R5 and R6 independently of one another are hydrogen or C1-C3-alkyl, X is oxygen or sulfur and A is a group     in which Y is oxygen, sulfur, -CH=CH-, -NR9- or -CR10-N-, R7 is hydrogen, halogen, C1-C3-alkyl, C1-C3-alkoxy, nitro or trifluoromethyl, R8 is hydrogen, halogen, C1-C3-alkyl, C1-C3-alkoxy, nitro, -C=CH, or one of the groups   R9 and R10 independently of one another are hydrogen, C1-C3-alkyl or C2-C4-alkenyl, R11 is hydrogen, C1-C3-alkyl, C1-C3-halogenoalkyl, C3-C6-cycloalkyl or C2-C4-aLkoxyalkyl, R12 is C1-C6-alkoxy, C3-C6-alkenyloxy, C3-C6-alkinyloxy, C2-C6-halo-genoalkoxy, C1-C4-cyanoalkoxy, C1-C6-alkylthio, C3-C6-alkenyl-thio, C3-C6-alkinylthio, C5-C6-cycloalkoxy, C2-C6-alkoxyalkoxy or -NR16R17, R13 is hydrogen, C1-C3-alkyl or C3-C4-alkenyl, R14 is hydrogens C1-C3-alkyl, C1-C3-cyanoalkyl or C1-C3-al-koxy, R15 is C3-C6-alkinyl, C2-C6-alkenyl, C1-C6-alkyl, C1-C4-halogenoalkyl, C2-C4-halogenoalkenyl or C1-C4-alkyl, sub-stituted by cyano, methoxy, ethoxy, nitro, C1-C4-alkoxycar-bonyl, methylthio, ethylthio, methylsulfonyl or ethylsulfonyl; or C3-C4-alkenyl substituted by nitro, cyano, methoxy or eth-oxy, R16 is hydrogen, C1-C3-alkyl or C3-C4-alkenyl, R17 is hy-drogen, C1-C3-alkyl, C1-C3-cyanoalkyl or C1-C3-alkoxy, R18 is C1-C3-alkyl and C1-C3-halogenoalkyl, W is oxygen or sulfur, Z is oxygen, sulfur, -SO- or -SO2- and m is the number zero or one.
Patent CA-1288269-C (CA)
Title: High capacity continuous package seam and tab folding  and tacking apparatus and method
Inventor: KONZAL DARYL
IPC: B65B61/24
Filed: 1987-11-12
Granted: 1991-09-03
Abstract: ABSTRACT           IMPROVED HIGH CAPACITY CONTINUOUS PACKAGE SEAM AND TAB FOLDING AND TACKING APPARATUS AND METHOD       Improved method and apparatus for contin-uously folding, heating, and tacking to the sides of the package panel the excess packaging material created by forming the package from a web of polyfoil material.  The method and apparatus is particularly useful in form, fill, and seal machines that form a plurality of aseptic sealed packages from a contin-uously advancing tube filled with a product, and incorporate a plurality of package receiving means mounted on a continuously advancing structure that forms sealed product filled packages into rectangular finished bricks by squaring the package, heating the excess material, folding the excess material against the package until it cools to thereby tack it.
Patent CA-1323154-C (CA)
Title: Apparatus and process for producing prills
Inventor: HUEY A MICHAEL
IPC: B29B9/00
Filed: 1988-01-19
Granted: 1993-10-19
Abstract: ABSTRACT         A prilling apparatus (10) and process for producing seed material for size enlargement processes such as a granulation process for bisphenol.  The apparatus (10) includes a fluidized bed system with a spray header (17) therein for producing spray droplets of material in a gaseous stream such as nitrogen to form prills of less than 1 mm diameter.
Patent CA-1305559-C (CA)
Title: Increased bandwidth for multi-processor access of a common resource
Inventor: CONFORTI JOSEPH A
IPC: G06F13/18
Filed: 1988-02-01
Granted: 1992-07-21
Abstract: INCREASED BANDWIDTH FOR MULTI-PROCESSOR ACCESS              OF A COMMON RESOURCE ABSTRACT OF THE INVENTION This circuitry permits equal access to a shared resource by a number of central processing units (CPUs).  In a multiple CPU arrangement, common resource contention problems arise, when several CPUs attempt to access the common resource. To resolve these contention problems, this circuitry is an improvement to arbitration ring circuitry.  The circuitry of this invention permits each of the CPUs equal access to the common resource during situations in which each CPU is constantly generating requests (high bandwidth utilization) for access to the common resource.  This invention is particularly useful for systems in which a large number of CPUs muse have their local memory rapidly reloaded from a common memory source.  Reloading procedures for large numbers of CPUs require up to an hour.  By employing the present invention, these reloading times can be cut from one hour to approximately 5 minutes.
Patent CA-1338701-C (CA)
Inventor: JANOFF ANDREW S
IPC: A61K47/14
Filed: 1988-02-29
Granted: 1996-11-12
Abstract: Methods and compositions are described for nonliposomal lipid complexes in association with toxic hydrophobic drugs such as the polyene antibiotic amphotericin B. Lipid compositions are preferably a combination of the phospholipids dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylglycerol (DMPG) in about a 7:3 mole ratio. The lipid complexes contain a bioactive agent and may be made by a number of procedures, at high drug:lipid ratios. These compositions of high drug:lipid complexes (HDLCs) may be administered to mammals such as humans for the treatment of infections, with substantially equivalent or greater efficacy and reduced drug toxicities as compared to the drugs in their free form. Also disclosed is a novel liposome-loading procedure, which may also be used in the formation of the HDLCs.
Patent CA-1283689-C (CA)
Title: Alternating current plasma display panel
Inventor: KNAUER PAUL E
IPC: H01J11/12
Filed: 1988-03-17
Granted: 1991-04-30
Abstract: ABSTRACT OF THE DISCLOSURE ALTERNATING CURRENT PLASMA DISPLAY PANEL.     Improvements in alternating current plasma display panels are disclosed including an imperforate intermediate structure in such a panel which provides both the function of a separator between the front and back plates of the panel and the function of crosstalk reducing barriers between cells of the panel. The structure includes spacing bosses which extend from the barrier structure and engage the front transparent dielectric plate, and sidewall portions intermediate adjacent pairs of spacing bosses which are separated somewhat from the front dielectric plate to provide a gas and ion passing gap between ad-jacent cells. In one preferred form, the sidewalls blend into a generally flat bottom wall within each cell. The sidewalls and bottom wall have a smooth or specular sur-face and may be coated with a reflective material to en-hance cell brightness.
Patent CA-1302041-C (CA)
Inventor: BEDICS MICHAEL A
IPC: E04F15/16
Filed: 1988-05-03
Granted: 1992-06-02
Abstract: ABSTRACT     An articulated floor mat structure is disclosed, in which a series of rigid, slat-like elements are hinged together and locked to prevent lateral movement, to form a mat structure that can be rolled up. The individual structural elements are shaped to provide for slide-in or snap-in assembly of tread strips, along their upper surfaces, and pad strips, along their lower surfaces. Edge strips are secured along the side edges of the mat assembly in an advantageous manner, to retain the tread strips and pad strips in assembled positions. An arrangement of integral loop tabs on the edge strips and integral hook tabs on the structural members greatly expedites the assembly process and correspondingly reduces the cost of manufacture, without compromising performance.
Patent CA-1341331-C (CA)
Inventor: WILD FABIAN
IPC: C07K19/00
Filed: 1988-07-05
Granted: 2002-01-01
Abstract: Recombinant pox virus expressing one or more of the structural proteins, HA, F and/or NP, of a morbilli virus, vaccine composed of this pox virus or of morbilli virus proteins which it synthesises. <IMAGE>
Patent CA-1324527-C (CA)
Title: Lipidic emulsion for parenteral or enteral use
Inventor: DUTOT GUY
IPC: A23L33/00
Filed: 1988-07-22
Granted: 1993-11-23
Abstract: Lipid emulsion for parenteral or enteral nutrition, wherein the lipid phase is a mixture of long-chain fatty acids in which essential fatty acids represent 15 to 45 % of the total fatty acids.
Patent CA-1294129-C (CA)
Inventor: COFFMAN GERALD C
IPC: D04D7/10
Filed: 1988-08-02
Granted: 1992-01-14
Abstract: DECORATIVE BOW STORABLE IN A FLAT CONFIGURATION            Abstract of the Disclosure A decorative device simulating a complex decorative bow knot in ribbon includes a base member and individual pieces which may be bent into a loop configuration, with each of the loop-configured pieces attached to the base member by corner portions which extend through slits defined in the base member.  The slits are preferably of two-legged "V" configuration in order to grip the loop members resiliently, and adhesive material may be used to hold the loop members in an arcuate loop configuration.  Adhesive material may also be used, together with or instead of the slits, to attach the loop members to the base member.  The bow may be made in large or small sizes and may be made in a form suitable for outdoor use at a modest cost.  The decorative bow, in a preferred embodiment, may be disassembled and stored flat as a set of parts.
Patent CA-1307964-C (CA)
Title: Thick, impact resistant antireflection coatings for ir transparent optical elements
Inventor: TUSTISON RANDAL W
IPC: G02B1/11
Filed: 1988-11-07
Granted: 1992-09-29
Abstract: Abstract of the Disclosure An impact resistant antireflection coating for an optical element which mitigates damage to the optical element when an air flight system having the optical element is flown through a high velocity droplet impact medium is described.  The coating comprises a material having a relatively high modulus of elasticity compared to the modulus of elasticity of the material of the optical element.  The coating is deposited to a half wavelength thickness at a wavelength which must be maximally transmitted through the optical element.  A quarter wavelength antireflection coating layer at the wavelength which must be maximally transmitted through the optical element is then disposed over the impact protection coating layer.  The material of the antireflection coating is preferably of a high modulus of elasticity material having a refractive index which is intermediate the refractive index of the material of the base layer and the medium through which the airborne system is flown.
Patent CA-1317955-C (CA)
Title: 3-¬4(1-substituted-4-piperazinyl)butyl|-4- thiazolidinones a process for their preparation and their use as medicaments
Inventor: HRIB NICHOLAS J
IPC: A61K31/425
Filed: 1988-11-18
Granted: 1993-05-18
Abstract: Abstract There are disclosed compounds of the formula,                 I   where n is 0 Qr 1; A is                   or                where X, Y, Z, U, V, W, Q, S and T   are each hydrogen, halogen, loweralkyl, hydroxy, nitro, loweralkoxy, amino, cyano or trifluoromethyl; m is 1 or 2; R1 and R2 are independently hydrogen, loweralkyl or aryl, or alternatively R1 + R2 taken together with the carbon atom to which they are attached form a cyclopentane, cyclohexane, cycloheptane, pyran, thiopyran, pyrrolidine or piperidine ring; R3 and R4 are independently hydrogen or loweralkyl, or alternatively R3 + R4 taken together with the carbon atom to which they are attached form a cyclopentane, cyclohexane, cycloheptane, pyran, thiopyran, pyrrolidine or piperidine ring, the term aryl signifying an unsubstituted phenyl group or a phenyl group substituted with 1, 2 or 3 substituents each of which being independently loweralkyl, loweralkoxy, hydroxy, halogen, loweralkylthio, cyano, amino or trifluormethyl,  and process for their preparation. The compounds are useful as antipsychotic, analgesic, anticonvulsant and anxiolytic agents.
Patent CA-1340105-C (CA)
Title: Process for the preparation of optically active 3-demethylmevalonic acidderivatives and intermediates
Inventor: WESS GUENTHER
IPC: C07D405/06
Filed: 1988-12-07
Granted: 1998-10-27
Abstract: A process for the preparation of optically active 3-de-methylmevalonic acid derivatives of the formula I                 (see fig. I) (3,5-dihydroxy carboxylic acid derivatives) or of the formula II    (see fig. II) (.beta.-hydroxy lactones) in which R, R1 and Y have the indicated meanings, is described.  The invention furthermore relates to aldehydes of the formula XII                 (see fig. III) in which M represents the indicated protective groups.
Patent CA-1332713-C (CA)
Title: Skin penetration enhancement using free base and acid  addition salt combinations of active agents
Inventor: PATEL DINESH C
IPC: A61K45/06
Filed: 1988-12-14
Granted: 1994-10-25
Abstract: ABSTRACT   SKIN PENETRATION ENHANCEMENT USING FREE BASE AND ACID ADDITION SALT COMBINATIONS OF ACTIVE AGENTS     The  invention  is  directed  to  compositions  for topical  application made  up  of  active  pharmaceutical permeants capable of existing in both free base and acid addition salt  form.   The permeants are present as a combination of both  free base and acid addition salt forms.   These combined forms provide skin penetration rates which are greater than the penetration rate of either  the  free  base  or  acid  addition  salt  forms utilized  separately.     The  combined  free  base-acid addition  salt  permeants  are  formulated  in  a  carrier vehicle which preferably also possesses skin penetration enhancement activity.
Patent CA-1310328-C (CA)
Inventor: MASSONNEAU VIVIANE
IPC: A61K31/415
Filed: 1989-01-13
Granted: 1992-11-17
Abstract: Process for preparing 1-(hydroxyalkyl)nitroimidazoles of formula: <IMAGE> (I)  which comprises reacting a sulphite or diacetate of an alkylenediol of formula: HO-(CH2)n-OH (II) in the presence of a strong acid (sulphuric acid) with an imidazole derivative of formula: <IMAGE> (III)  followed by hydrolizing or alcoholizing the product obtained. In the formulae (I) and (III), R denotes hydrogen or hydrocarbon. In the formulae (I) and (II), n is 2 or 3. In the formula (III), X denotes hydrogen or a radical which can be removed by hydrolysis or alcoholysis.
Patent CA-1311919-C (CA)
Inventor: PERRI JOSEPH A
IPC: F27D3/16
Filed: 1989-01-25
Granted: 1992-12-29
Abstract: ABSTRACT OF THE DISCLOSURE    An improved device for introducing gas into a mass of molten metal in a container having a refractory lining, the device comprising a body member having upper and lower surfaces and an outwardly extending flange positioned for engagement within said refractory lining; a plurality of passageways in said body member arranged in a spiral cone-shaped pattern ex-tending to the upper surface of the body member and communicating with an opening in the lower surface of the body member, said body member forming an integral portion of said refractory lining in said container for said molten metal, said passageways arranged to form a plurality of streams of gas rising in said molten metal when gas is introduced through said device whereby swirling stirring motion is imparted to said molten metal.
Patent CA-1331818-C (CA)
Title: Polyethylene alkyl acrylate adhesive composition
Inventor: OVERBERGH NOEL M M
IPC: C09J123/08
Filed: 1989-02-24
Granted: 1994-08-30
Abstract: ABSTRACT       A hot-melt adhesive composition which comprises a mixture of:         (a) 25-40 parts by weight of a polyethylene alkyl acrylate terpolymer containing maleic anhydride and having a melt flow index as determined according to ASTM D1238-70 of at least 40; and (b) 25-70 parts by weight of a polyethylene alkyl acrylate copolymer having a melt flow index as determined according to ASTM D1238-70 of at least 40.
Patent CA-1321031-C (CA)
Title: Networked programmable logic controller system and ladder editor
Inventor: GATES DIRK I
IPC: G05B19/05
Filed: 1989-04-04
Granted: 1993-08-03
Abstract: ABSTRACT OF THE DISCLOSURE     A programmable logic controller system including a programmable logic controller having an input/output scanner for reading data from and writing data to peripheral controllers as determined by a ladder diagram.  Each of the peripheral controllers controls a plurality of data points.          A input/output scanner includes a processor coupled to input/output ports.  The input/output ports couple to the peripheral controllers.  The system includes a memory for storing data read from and to be written to the peripheral controllers.  There is a logic scanner for executing compiled boolean logic statements representing the ladder diagram.
Patent CA-1326787-C (CA)
Title: Round baler with variable bale chamber
Inventor: JENNINGS RICHARD E
IPC: A01F15/07
Filed: 1989-04-13
Granted: 1994-02-08
Abstract: ROUND BALER WITH VARIABLE BALE CHAMBER                  ABSTRACT OF THE DISCLOSURE A round baler includes an apron having an expandable inner course which cooperates with a sledge assembly to define a bale starting chamber when the sledge assembly is in a bale starting position.  The sledge assembly is movable between the bale starting position and a full bale position.  The sledge assembly includes a plurality of rollers and an idler roller in engagement with the apron to maintain the apron in close proximity to one of the rollers during movement of the sledge assembly between the bale starting and full bale positions.
Patent CA-1325730-C (CA)
Title: Radiation transducing device
Inventor: DIERICKX BART M H L
IPC: H04N5/335
Filed: 1989-05-25
Granted: 1994-01-04
Abstract: ABSTRACT     A radiation transducer has an array of elements sensitive to radiation and comparator elements connected to the radiation sensitive elements, for comparing the amount of radiation received by a  radiation sensitive element with a predetermined threshold value,  An encoding element is connected to each comparator element for producing a digital representation of the element on which radiation is incident and a measuring element is connected to the radiation sensitive elements for determining the amount of radiation incident on the corresponding element during a predetermined time period.
Patent CA-1306983-C (CA)
Title: Hockey stick carrier
Inventor: LAMADELEINE JOSEPH F M
IPC: A63B71/00
Filed: 1989-06-05
Granted: 1992-09-01
Abstract: ABSTRACT   A carrier for elongated equipment for sports, such as hockey, golf, skiing, curling, ringette, or the like: The carrier is designed to hold two or more pieces of equipment and comprises at least a pair of U-shaped channels formed of resilient plastic material.    The U-shaped  channels are  so dimensioned that the channels open  to  receive  a  hockey  stick,  for  example,  and  develop resilient  force  to  engage  the hockey sticks inserted therein. Normal means for attaching a  carrying  strap  is  provided  in a manner which permits low-cost mass production.
Patent CA-1316789-C (CA)
Title: High-density granular concentrated detergent composition
Inventor: NEBASHI TUTOMU
IPC: C11D3/37
Filed: 1989-07-04
Granted: 1993-04-27
Abstract: ABSTRACT OF THE DISCLOSURE      A high density ,      granular, concentrated detergent composition  comprises:          (1) 30 to 50 wt.% of an anionic surface active agent, (2) 40 to 60 wt.% of an inorganic builder, (3) a fluorescent dye, (a) 5 to 25 wt.% of potassium salt of an anionic surfactant or 2 to 10 wt.% of potassium carbonate or potassium sulfate, (b) 0.1 to 3 wt.% of sodium chloride and (c) 0.2 to 5 wt.% of polyethylene glycol having a molecular weight of 6,000 to 20,000.