baber/WOPTO huggingface dataset:
Patent EP-3783097-A1 (EP)
Inventor: NISHIDA KOHJI
IPC: C12N5/074
Filed: 2019-05-22
Abstract: Provided is a method for inducing differentiation into conjunctival epithelial cells, conjunctival goblet cells, and conjunctival epithelial stem and progenitor cells, the method comprising culturing colonies of pluripotent stem cells in a medium containing an epidermal growth factor (EGF) signaling activator to induce differentiation of the pluripotent stem cells. The present invention enables differentiation of pluripotent stem cells including iPS cells into conjunctival epithelial cells, conjunctival goblet cells, and conjunctival epithelial stem and progenitor cells and therefore is very useful for, for example, basic research on conjunctival epithelial cells and conjunctival goblet cells, regenerative therapy for intractable ocular surface diseases, and research related to the diseases.
Patent EP-3809954-A1 (EP)
Title: Monitoring physiologic parameters for timing feedback to enhance performance of a subject during an activity
Inventor: TOTH LANDY
IPC: A61B5/022
Filed: 2019-05-20
Abstract: A method includes monitoring first and second sets of physiologic parameters from at least one site on a subject utilizing at least one sensing device, identifying first and second events related to the first and second sets of physiologic parameters, generating first and second timestamps for the first and second events, determining a timing for providing feedback to the subject relative to the first timestamp and the second timestamp to adjust one or more characteristics of the subject during an activity, and providing one or more feedback signals to the subject in accordance with the determined timing utilizing at least one stimulating device. Adjusting one or more characteristics of the subject during the activity may include enhancing cardio-pulmonary performance of the subject during the activity, providing biomechanical enhancement of movement of at least a portion of the subject during the activity, or both.
Patent EP-3887703-A1 (EP)
Inventor: SCHRÖTER DIRK
IPC: F16L37/098
Filed: 2019-11-22
Abstract: The invention relates to a fluid connection (10), comprising a first connection body (12), a second connection body (14) and a latching body (16), which is designed to connect the first connection body (12) to the second connection body (14), the latching body (16) having a first latching device (28) that cannot be released in a destruction-free manner and a second latching device (54) that can be released in a destruction-free manner, and the latching body (16) being designed to be pushed onto a radially outer side of the first connection body (12) and onto a radially outer side of the second connection body (14).
Patent EP-3804925-A1 (EP)
Inventor: TAKASHIMA YOSUKE
IPC: B26B3/00
Filed: 2019-05-30
Abstract: A safety utility knife includes a resin-made grip part 31, a blade 50a, 50b projecting from the grip part, and a resin-made head part 33a, 33b arranged at a tip of the projecting blade. The blade is formed with a through-hole so that a resin-made coupling part 35 lying within the through-hole couples together the grip part 31 and the head part 33a, 33b that are made of resin. Since the safety utility knife of the present invention allows the three resin-made parts to be joined together, it can be manufactured easily and at low cost using a 1-gte type mold. Also, there is no unnecessary increase in the blade thickness, preventing an increased cutting resistance and a rough cut end from occurring.
Patent EP-3884118-A1 (EP)
Inventor: SMIT NICOLAAS PETRUS FREDERIKUS MARIA
IPC: E03F5/02
Filed: 2019-11-25
Abstract: A packer (2) for use in a method for lining interior walls of a hollow structure that communicates with a pipe provided in a wall of the hollow structure is described. The packer (2) comprises rigid end parts (20a, 20b) and a flexible part (21) that connects to the rigid parts, and spacing means (26) that keep the rigid parts at an adjustable distance from each other in an axial direction of the packer. The flexible part comprises an inner covering layer facing the inside of the packer, an outer covering layer facing the outside of the packer, and a packer material sheet of reinforcing fibers and a curable resin composition provided in between the inner and outer covering layer. The packer further comprises a means (23) for pressurizing the inside of the packer, and a curing means (25) provided within the inside of the packer for curing the packer resin composition. A lining method in which the packer is used, is also described, as well as a method for providing a pipe with a hat section.
Patent EP-3874028-A1 (EP)
Inventor: ROUSSET XAVIER
IPC: G01N33/50
Filed: 2019-10-29
Abstract: The invention relates to the use of an embryonated egg model grafted with tumor cells to study the anti-cancer effectiveness or screen immunotherapeutic molecules in the absence of immune effector cells other than those in the grafted egg.
Patent EP-3806949-A1 (EP)
Inventor: SABIEV ANTON
IPC: A61N1/30
Filed: 2019-06-14
Abstract: An iontophoresis system for positioning against skin of a subject is disclosed. The iontophoresis system can comprise at least one vessel having a solvent therein. An anode apparatus can couple to the at least one vessel. The anode apparatus can comprise a first reservoir configured to receive the solvent from the at least one vessel so that, when received into the first reservoir, the solvent makes contact with the skin of the subject, and a first electrode positioned above the first reservoir. A cathode apparatus can couple to the at least one vessel. The cathode apparatus can comprise a second reservoir configured to receive the solvent from the at least one vessel so that, when received into the first reservoir, the solvent makes contact with the skin of the subject, and a second electrode positioned above the second reservoir.
Patent EP-3887934-A1 (EP)
Inventor: BEDI KAWARJIT
IPC: G06F8/60
Filed: 2019-11-22
Abstract: A coordinated network service that facilitates the design and implementation of a coordinated device network of IoT devices. The coordinated network service defines modules for individual IoT devices or coordinated devices that specify the necessary inputs to the device, the outputs from the device and communication protocols. Via an interface, user devices can select a set of IoT devices and specify how they are connected and the decision making logic associated with communication flow. The coordinated network service can then automatically generate mapping information that implements the decision making logic and provides necessary transformations for communications between the specified devices. The selected modules and mappings form a workflow for the coordinated device network. The coordinated network service can then generate executable code to implement the formed workflow in a coordinated device network.
Patent EP-3891363-A1 (EP)
Inventor: MARTIN SCOTT
IPC: F02C7/04
Filed: 2019-12-04
Abstract: A turbofan engine assembly includes a fan, a fan case, and a fan case liner. A fan blade has a fan blade tip at the distal end of the fan blade. The fan case liner is spaced apart from the fan blade tip by a clearance distance, is disposed between the fan case and the fan blade tip, and includes an abradable base layer and an abradable indicator layer. The abradable base layer is in closest proximity to the fan and has a first visual characteristic and a depth matching a clearance threshold allowable value. The abradable indicator layer is disposed between the abradable base layer and the fan case. The abradable indicator layer has a second visual characteristic that is visually distinguishable from the first visual characteristic to indicate when the abradable base layer has worn away such that the clearance distance has exceeded the clearance threshold allowable value.
Patent EP-3941604-A1 (EP)
Inventor: DONALDSON THOMAS ALAN
IPC: A63H33/26
Filed: 2019-12-12
Abstract: An interactive toy comprises a toy housing and, accommodated in said toy housing: a function device for performing user-perceptible, controllable functions; a control circuit for controlling the function device; a rechargeable power source for providing operating power to the function device and the control circuit; and a charging circuit for contactless receipt of electrical energy and for charging the rechargeable power source when the interactive toy is positioned in a charging zone of a contactless charging device. The control circuit is configured to: receive a primary signal indicative of an interaction stimulus; receive a secondary signal indicative of a position of the interactive toy with respect to the charging zone; and, responsive to the primary signal, control the function device to perform a user-perceptible function, wherein the user-perceptible function is selected based on the secondary signal. An interactive toy system comprises an interactive toy and a contactless charging device defining one or more charging zones. Methods of controlling the interactive toy and the interactive toy system are provided.
Patent EP-3899555-A1 (EP)
Inventor: BÜMING ANDREAS
IPC: G01R19/175
Filed: 2019-12-18
Abstract: A method and a system for determining a phase shift between a phase current and a phase voltage in an AC phase line of a converter. A method and a system for determining a phase shift between a phase current (I u , I v , I w ) and a phase voltage (U u , U v , U w ) in an AC phase line (U, V, W) of a converter (5), in particular a converter (5) of a system for inductive power transfer, wherein a phase current change dependent quantity is determined, wherein a voltage-specific reference time point is determined depending on the phase current change dependent quantity, wherein the phase current (I u , I v , I w ) is determined, wherein a current-specific reference time point is determined depending on the phase current (I u , I v , I w ), wherein the phase shift is determined depending on the time difference between the voltage-specific reference time point and the current-specific reference time point.
Patent EP-3829970-A1 (EP)
Inventor: PAULL ADAM J
IPC: B63B43/14
Filed: 2019-05-30
Abstract: An embodiment includes an open/non-closed hull collar assembly shaped to increase encapsulated volume of a hull. The hull collar assembly includes a hull collar structure and a foam module. The hull collar structure includes a gunwale, an outboard boundary, and an inboard boundary. The outboard boundary extends in an outward lateral direction from a lower hull portion and extends in a longitudinal direction from the lower hull portion such that at least a portion of the hull collar structure is at least partially included in a freeboard portion of a boat hull. The inboard boundary extends from the gunwale a portion of a distance to a deck such that the hull collar structure is at least partially open or non-closed to an inner hull volume. The foam module is comprised of a non-expansive, closed cell foam. The foam module is shaped for disposition within the hull collar structure.
Patent EP-3830248-A1 (EP)
Inventor: BEARD BRIAN
IPC: C12N5/074
Filed: 2019-07-30
Abstract: The present invention relates generally to methods for genetic modification of hematopoietic cells. In particular, the invention relates to use of Prostaglandin E2 (PGE2), poloxamer, and protamine sulfate to enhance transduction by a recombinant retroviral vector. The compositions and methods of the present disclosure are particularly suitable for gene therapy applications, including the treatment of monogenic genetic diseases and disorders.
Patent EP-3827628-A1 (EP)
Inventor: LU QIANXI
IPC: H04W72/04
Filed: 2019-06-28
Abstract: Methods and devices for indicating PDCCH resources are provided. The method includes: a network device generates an instruction for PDCCH resources for subframes (S110); the network device sends the instruction for PDCCH resources (S120); a terminal device receives the instruction for PDCCH resources for subframes (S130); the terminal device determines a number of symbols for PDCCH for a MBSFN subframe based on the first instruction and a number of symbols for PDCCH for a non-MBSFN subframe based on the list of indications in the second instruction (S140).
Patent EP-3844566-A1 (EP)
Inventor: LUTEN HENRY A
IPC: G02F1/166
Filed: 2019-08-27
Abstract: A controller system configured to clear an electro-optic device may include an electro-optic device having a first substrate having a first surface and a second surface, the second surface having a first layer of electrically conductive material disposed thereon; a second substrate having a first surface having a second layer of electrically conductive material disposed thereon, and a second surface, the second substrate being approximately parallel to the first substrate such that a chamber is defined by the first and second substrates; and an electro-optic medium disposed in the chamber defined by the first and second substrates and in contact with the first and second layers of electrically conductive material; a controller in communication with the electro-optic device, wherein the controller is configured to control electrical power supplied to the electro-optic device and a potentiometer in communication with the electro-optic device and with the controller.
Patent EP-3852815-A1 (EP)
Inventor: KIM DAVID
IPC: A61M31/00
Filed: 2019-09-09
Abstract: Described herein are compositions composed of a radiopaque agent and a cyanoacrylate monomer. These compositions cure  in situ  when administered to a subject and, thus, have numerous biomedical applications. The presence of the radiopaque agent allows the practitioner to visualize the compositions during and immediately after administration to the subject. The compositions are non-toxic and shelf-stable, and can be sterilized to prevent microbial growth. The compositions can be pre-mixed prior to sale and distribution, reducing the need for special training in their use.
Patent EP-3852769-A1 (EP)
Inventor: LI ZHEN
IPC: C12N15/113
Filed: 2019-09-18
Abstract: The present disclosure relates to RNAi agents, e.g., double stranded RNAi agents, able to inhibit l7P-hydroxy steroid dehydrogenase type 13 (HSD17B13 or 17β-Η8013) gene expression. Also disclosed are pharmaceutical compositions that include HSD17B13 RNAi agents and methods of use thereof. The HSD17B13 RNAi agents disclosed herein may be conjugated to targeting ligands to facilitate the delivery' to cells, including to hepatocytes. Delivery7 of the HSD17B13 RNAi agents in vivo provides for inhibition of HSD17B13 gene expression. The RNAi agents can be used in methods of treatment of HSD17B13-related diseases and disorders, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), hepatic fibrosis, and alcoholic or non-alcoholic liver diseases, including cirrhosis.
Patent EP-3852917-A1 (EP)
Inventor: GUTTMAN MITCHELL
IPC: C07K1/04
Filed: 2019-09-17
Abstract: In some embodiments, methods of detecting an association between a query protein and a target moiety are described. In some embodiments, compositions are described. In some embodiments, kits are described.
Patent EP-3839367-A1 (EP)
Inventor: BAK JONG WON
IPC: F24F11/54
Filed: 2019-08-19
Abstract: An air conditioner includes an outdoor unit; a plurality of mode change devices connected to the outdoor unit, including at least one mode changer including a branch duct and a changing valve, and configured to receive a control signal from the outdoor unit to control an operation of the at least one mode changer; and a plurality of indoor units connected to the outdoor unit or the plurality of mode change devices. The outdoor unit may be configured to determine an operation mode of the plurality of mode change devices to operate the plurality of mode change devices a plurality of times. Each of the plurality of indoor units may be configured to detect a temperature change of an indoor heat exchanger in response to the operation of the plurality of mode change devices, to determine the number of connected mode changers and a connectable mode changer candidate group based on the temperature change of the indoor heat exchanger, and to extract a valid mode changer from the determined mode changer candidate group and obtain branch duct connection information.
Patent EP-3858324-A1 (EP)
Inventor: HIRONO SHINGO
IPC: A61K8/891
Filed: 2019-09-30
Abstract: An external preparation containing the following component (A) and component (B). Component (A): ionic polymer particles containing structural units derived from (a) one or more hydrophobic monomers selected from the group consisting of styrene and a derivative thereof, a vinyl ester, and a hydrophobic acrylic monomer, and (b) an ionic hydrophilic monomer or a salt thereof, wherein the ratio by mass of (a) to (b), (a)/(b) is 99.5/0.5 to 80/20, and the ionic polymer particles have a glass transition temperature of higher than 5°C and 120°C or lower. Component (B): one or more compounds selected from the group consisting of a phenoxyethanol (B1), a 2-ethylhexyl paramethoxycinnamate (B2), a benzyl alcohol (B3), a sorbitol (B4), a specific oxyalkylene derivative (B5), a polyoxyalkylene alkyl glucoside (B6), an oleic acid (B7), an alkyl benzoate (B8), a xylitol (B9), a 2-ethylhexyl (RS)-2-cyano-3,3-diphenylprop-2-enoate (B10), and a methylphenylpolysiloxane (B11).
Patent EP-3858865-A1 (EP)
Inventor: GAO YONGJUAN
IPC: C12N15/00
Filed: 2019-09-24
Abstract: Disclosed is a fusion protein of a mutated recombinant single-chain human coagulation factor VIII (FVIII), a preparation method therefor, and a use thereof. The fusion protein sequentially comprises, from an N-terminus to a C-terminus, a mutated single-chain human FVIII having a partially deleted B-domain, a flexible peptide linker, at least one rigid unit of a carboxyl-terminal peptide of a human chorionic gonadotropin beta subunit, and a half-life prolonging moiety (preferably an IgG Fc variant). The fusion protein has a similar biological activity to a recombinant FVIII, a prolonged active half life in vivo, and better stability in vitro and in vivo, and thus improves the pharmacokinetics and efficacy of the fusion protein.
Patent EP-3869678-A1 (EP)
Inventor: SASAO KAZUKI
IPC: H02M3/155
Filed: 2019-10-18
Abstract: A DC/DC converter 200A includes N inductors L1_1 to L1_N and N power modules 220_1 to 220_N which correspond to N phases. At least one of the N power modules is mounted on a sub-mounting surface SB that is opposite to a main mounting surface SA of a printed circuit board 300A.
Patent EP-3871536-A1 (EP)
Inventor: YAMADA MANABU
IPC: A24F47/00
Filed: 2019-01-15
Abstract: A main body unit of an aerosol generation device that is at least dividable into a first unit and a second unit according to an aspect of the present invention has a rotation connection mechanism configured to connect the first unit and the second unit by inserting an engagement convex portion disposed in either of the first unit or the second unit into an engagement groove portion disposed in the other one of the first unit or the second unit and rotating in a first rotation direction around a central axis of the main body unit; a first convex portion disposed in either of the first unit or the second unit, the first convex portion protruding outwardly in a radial direction orthogonal to the central axis; and a second convex portion disposed in the other of the first unit or the second unit, the second convex portion protruding inwardly in the radial direction, wherein when a connection is performed in the rotation connection mechanism, either of the first convex portion or the second convex portion is elastically deformed in the radial direction while climbing over the other one of the first convex portion or the second convex portion and engaged with the other one of the first convex portion or the second convex portion in a second rotation direction opposite to the first rotation direction.
Patent EP-3913198-A1 (EP)
Inventor: TANG WANFU
IPC: F24F8/80
Filed: 2019-10-21
Abstract: An engine air intake dust removal system and method, comprising an air intake dust removal system inlet (1011), an air intake dust removal system outlet and an air intake electric field device (1014). The air intake dust removal system (101) and method can effectively remove particulate matters from air trying to enter the engine, and make the air entering the engine cleaner.
Patent EP-3871936-A1 (EP)
Inventor: LAI JIANMING
IPC: B60W30/06
Filed: 2019-06-28
Abstract: The present disclosure provides a safe distance warning method for automatic parking. The safe distance warning method includes: in a process of controlling automatic parking of a vehicle in a parking space, determining, in response to detecting a dangerous obstacle having a distance from a body of the vehicle smaller than a preset safe distance, a real orientation of the dangerous obstacle relative to a real geographic position of the vehicle; and displaying a vehicle icon of the vehicle and a warning icon on a screen. A virtual orientation of the warning icon relative to the vehicle icon corresponds to the real orientation. The method can warn a user that a distance between a body of a vehicle and an obstacle is too close in a simple and intuitive visualization manner. The present disclosure also relates to a vehicle-mounted terminal.
Patent EP-3869986-A1 (EP)
Inventor: ROCKENFELLER UWE
IPC: F41H5/007
Filed: 2019-10-07
Abstract: La présente invention concerne un écran de dissipation de chaleur qui comprend une configuration stratifiée qui réduit les dégâts d'une surface revêtue de l'écran. Par exemple, l'écran peut comprendre une couche d'étanchéité et une couche de composé complexe hydraté, de telle sorte que le composé complexe hydraté libère de la vapeur d'eau lorsque l'écran est exposé à de la chaleur. La vapeur d'eau peut s'échapper de l'écran sans endommager la surface protégée par l'écran.
Patent EP-3892518-A1 (EP)
Inventor: WANG HUAWEI
IPC: B61L23/14
Filed: 2019-11-11
Abstract: A train speed limit control method and device. The train speed limit control method comprises: detecting whether instability occurs during travelling of a train (S201, S301, S401, S501); if it is detected that instability occurs during travelling of the train, braking the train to limit the train speed to a first speed for traveling (S202, S302, S402, S502). The train speed limit control method implements automatic speed limit control during travelling of a train. The application of the train speed limit control method to train travel control can reduce the labor intensity of the driver, and automatically and timely limit the train speed when instability occurs during traveling of the train, thereby effectively preventing train travel safety from being affected by the driver's negligence.
Patent EP-3891770-A1 (EP)
Inventor: HERLE SUBRAMANYA P
IPC: H01G11/26
Filed: 2019-09-19
Abstract: The present disclosure generally relates to a method and apparatus for uniformly pre-lithiating one or more lithium ion capacitor anodes. A substrate comprising one or more anodes is provided to a flexible substrate coating apparatus as a continuous sheet of anode material, and a lithium layer is uniformly and directly deposited onto one or more sides of the substrate using the flexible substrate coating apparatus.
Patent EP-3813324-A1 (EP)
Inventor: YU CHAOFAN
IPC: H04L29/06
Filed: 2019-10-22
Abstract: Implementations of the present specification provide a data processing method and apparatus. A method performed by a data provider includes: obtaining first encrypted data of first plaintext data, a first key used to decrypt the first encrypted data, and authorization information about the first plaintext data; sending a verification request to a data manager, the data manager including a first trusted execution environment; receiving authentication information from the data manager, and performing verification based on the authentication information; when the verification succeeds, securely transmitting the first key and the authorization information to the first trusted execution environment; and providing the first encrypted data to the data manager.