baber/WOPTO huggingface dataset:
Patent EP-3752137-A1 (EP)
Inventor: PRUTEANU MIHAELA
IPC: A61K31/137
Filed: 2019-02-13
Abstract: The present invention relates to agents and compositions for the modification of the growth of bacterial cells. Thus, the compounds of the present invention are useful for the prevention and/or treatment of a disease in a subject. In particular, the present invention relates to the field of repurposing pharmaceutical compounds for treatment strategies of infectious diseases,gastrointestinal disorders, inflammatory diseases, proliferative diseases, metabolic disorders, cardiovascular diseases, and immunological diseases. Some of the compounds of the present invention demonstrate high specificity in inhibiting the growth of single bacterial species. Such compounds enable narrow-spectrum antibacterial therapies, constituting a major effort of current and future drug development strategies in order to reduce side effects of antibacterial treatment plans. Particularly interesting compounds of this invention are effective against pathobiological species such as  Clostridium difficile,Clostridium perfingens ,  Fusobacterium nucleatum , and an enterotoxigenic strain of  Bacteroides fragilis . Other compounds of the present invention reveal a strong inhibitory effect on a broad spectrum of bacterial species. Such compounds are useful for broad-spectrum antibiotic therapies of infections with unknown causative infecting bacterial species.Both types of compounds, especially the ones with narrow-spectrum antibacterialactivity, can further be used for modulating the microbiome composition and targeting species associated with dysbiosis and disease.
Patent EP-3749924-A1 (EP)
Title: Tilt and distance profiling vehicle
Inventor: PATEL SAHEJAD
IPC: G05D1/02
Filed: 2019-02-06
Abstract: Disclosed herein are systems and methods for profiling a surface. In some embodiments, the systems and methods perform profiling using a robotic vehicle. The vehicle can include a drive system, one or more wheel encoders, and one or more distance sensors and/or inertial measurement units for capturing measurement data, such as the slope of the surface or the angle of the robotic vehicle relative to the surface or the gravity vector. A control computing system is included having one or more processors that execute instructions stored in software modules to process movement data. In some embodiments, the processed movement data determines a plurality of snapshots of the surface at different times and positions as the robotic vehicle traverses the surface. These snapshots are combined to generate a profile of the surface.
Patent EP-3766055-A1 (EP)
Inventor: KIME SIHEM
IPC: A61B5/00
Filed: 2019-03-13
Abstract: L'invention concerne un système et un procédé de traitement de multiples signaux générés par un traitement de capteurs pour identifier et/ou surveiller des données physiologiques d'un individu (par exemple dans un système de soins de santé) ou la situation générale d'un environnement, d'un espace prédéfini (par exemple une pièce, une machine ou un bâtiment) ou d'un objet (par exemple dans un système domotique, un système de surveillance d'environnement, un système de prévention des incendies ou autres).
Patent EP-3906127-A1 (EP)
Inventor: BHARODIYA VISHAL KALUBHAI
IPC: B21D53/30
Filed: 2019-02-06
Abstract: The present disclosure discloses a method for manufacturing a wheel disc for a vehicle. The method comprises drawing a substantially central portion of a blank of metal into a hat-shaped profile, and forming a plurality of bolt seats and beads on an inner flat surface of the hat-shaped profile. The method further comprises bending an outer flat surface of the hat-shaped profile to define an outer flange of the wheel disc and drawing a central portion of the hat-shaped profile to define a central flange of the wheel disc. With the method of present disclosure, number of manufacturing steps to manufacture the wheel disc is reduced by about 15% - 30% when compared to manufacturing steps of a conventional method without affecting final shape of the wheel disc.
Patent EP-3746169-A1 (EP)
Inventor: LIPPERT JOHN A
IPC: A61M25/09
Filed: 2019-03-06
Abstract: The present disclosure relates to guidewire devices (900) having shapeable tips and effective torquability. A guidewire device includes a core (902) having a proximal section and a tapered distal section. A tube structure (904) is coupled to the core such that the tapered distal section extends into the tube structure. The tube structure includes a plurality of bypass cuts (930, 940) formed tangentially within the tube structure to increase the flexibility of the tube structure and to reduce the tendency of resilient forces from the tube structure to disrupt a shaped distal tip of the guidewire device.
Patent EP-3759177-A1 (EP)
Inventor: EHRHARDT THORSTEN
IPC: C09D5/00
Filed: 2019-02-28
Abstract: The invention relates to a dispersion-based coating containing, each relative to the total weight of the dispersion paint, a) 0.1 to 30 wt.% pigment, b) 5 to 65 wt.% filler, c) 1 to 35 wt.% polymer, d) 0.01 to 1 wt.% calcium hydroxide, e) 5 to 70 wt.% water, the pH level of the dispersion paint being from 10.5 to 12. The dispersion-based coating is suitable for interior and/or exterior use.
Patent EP-3571331-A1 (EP)
Inventor: SARGENT EDWARD
IPC: H01M8/1004
Filed: 2019-03-26
Abstract: L'invention concerne un catalyseur de réduction de dioxyde de carbone (CO2) multicouche composite, comprenant une couche de catalyseur comprenant au moins un composé métallique, la couche de catalyseur présentant des premier et second côtés opposés ; une couche de diffusion de gaz hydrophobe disposée sur le premier côté de la couche de catalyseur ; une structure de collecte de courant disposée sur le second côté de la couche de catalyseur. Le métal est de préférence du cuivre. L'invention concerne également un procédé de production électrochimique d'un produit hydrocarboné, tel que de l'éthylène, mettant en œuvre ledit catalyseur.
Patent EP-3777366-A1 (EP)
Title: Flexible selection of timing advance control method for supplementary uplink connections
Inventor: SANDGREN MAGNUS
IPC: H04W56/00
Filed: 2019-03-26
Abstract: Exemplary embodiments include methods adjusting transmission timing of a wireless communication device (UE) operating in a network comprising first and second base stations (BS). The methods include determining a first allowable timing adjustment range corresponding to an uplink (UL) connection between the UE and the first BS. The methods include determining a second allowable timing adjustment range corresponding to a supplementary uplink (SUL) connection between the UE and the second BS, wherein the SUL connection is not associated with a DL connection between the UE and the second BS. The methods include determining if a single timing advance (TA) value can be used to adjust the UE's transmission timing to satisfy both the first and second ranges, and performing a corrective action if it is determined that said single TA value cannot be used. Embodiments also include first and second BS, and UEs, configured to perform various aspects of the exemplary methods.
Patent EP-3766057-A1 (EP)
Title: A method for signalling the state of an element of transport infrastructure and a set for the realisation of this method
Inventor: RYKOWSKI JAROGNIEW
IPC: G08G1/005
Filed: 2019-03-11
Abstract: The object of the invention is a method for signalling the state of an element of transport infrastructure, wherein: - a radio transmission module operating in a 2.4 GHz band, using the IEEE 802.15.1 communication standard (Bluetooth) mounted on an element of transport infrastructure transmits in a broadcasting mode, unidirectionally without confirmation, a signal comprising digital information including the identifier, type and state of an element of transport infrastructure; - a portable telephone or computer device, in particular a smartphone, a tablet or a laptop, provided with a receiver operating in a 2.4 GHz band, using the IEEE 802.15.1 communication standard (Bluetooth) receives said signal comprising digital information, processes this information and according to the user's predefined settings - notifies the user, in particular by means of an acoustic, mechanical and in particular vibrating signal, and/or a visual signal, in particular in the form of a displayed message, image or animation on the screen of said portable telephone or computer device. The invention also comprises a set for the realisation of this method.
Patent EP-3784288-A1 (EP)
Title: Modified aav capsid polypeptides for treatment of muscular diseases
Inventor: GRIMM DIRK
IPC: C12N15/864
Filed: 2019-04-26
Abstract: The present invention relates to an adeno-associated virus (AAV) capsid polypeptide bonded to a binding peptide comprising an amino acid sequence RGDX 1 X 2  X 3  X 4 , with X 1  to X 4  being independently selected amino acids, for use in treating and/or preventing a muscular disease and/or in muscle regeneration. The present invention further relates to polynucleotides, host cells, adeno-associated virus (AAV) capsids, pharmaceutical compositions, uses, and methods related to said AAV capsid polypeptide.
Patent EP-3773344-A1 (EP)
Title: Ceramic surface arthroplasty system
Inventor: VLACHOS IOANNIS
IPC: A61F2/36
Filed: 2019-04-02
Abstract: The invention relates to a ceramic surface arthroplasty system, which consists of a convex, hemispherical, metallic implant (1) and a hollow hemispherical metal implant (3). The implants are coated with porcelain or zirconium oxide layer on their friction surfaces to avoid the creation of metallic microparticles. The convex implant (1) has a navel (4) on the thread (6) of which a bone-piercing pre-tensioning needle (7) is screwed and is tightened with a washer (9) at the area of the major trochanter or bulge. Further, it has protruding ribs (5) immersed on the surface of the head.
Patent EP-3796865-A1 (EP)
Inventor: SALAH PHILIPPE
IPC: A61C7/00
Filed: 2019-05-14
Abstract: The invention relates to a method for analysing a real dental situation of a patient, the method comprising the following successive steps: A) at an updated instant, acquiring an updated image representing a real dental scene as observed by an operator; B) simulating, for a simulation instant, the real dental scene represented on the updated image, then determining a virtual dental scene according to said simulation; and C) presenting the virtual dental scene transparently and superimposed over the real dental scene, or displaying the updated image on a screen and presenting the virtual dental scene superimposed, with the representation of the real dental scene on the updated image displayed on the screen, transparently or not, over said representation.
Patent EP-3791527-A1 (EP)
Inventor: FRÖBERG OLSSON JONAS
IPC: H04L5/00
Filed: 2019-05-10
Abstract: Embodiments of a method performed by a wireless device for receiving and interpreting a Downlink Control Information (DCI) message having a flexible DCI format and embodiments of a corresponding wireless device are disclosed. In some embodiments, a method performed by a wireless device for receiving and interpreting a DCI message comprises receiving a DCI message from a base station and obtaining a DCI formatting indicator for the DCI message. The DCI formatting indicator is an indicator related to a flexible-interpretation DCI format, wherein the flexible-interpretation DCI format is a DCI format for which bits are interpreted differently based on the DCI formatting indicator. The method further comprises interpreting the DCI message in accordance with the DCI formatting indicator. Embodiments of a method performed by a base station for transmitting a DCI message having a flexible DCI format and embodiments of a corresponding base station are disclosed.
Patent EP-3710894-A1 (EP)
Title: Methods for fabricating optical waveguides
Inventor: WALDERN JONATHAN DAVID
IPC: G03H1/20
Filed: 2019-01-08
Abstract: Mastering systems and methods of fabricating waveguides and waveguide devices using such mastering systems are described. Mastering systems for fabricating holographic waveguides can include using a master to control the application of energy (e.g. a laser, light, or magnetic beam) onto a liquid crystal substrate to fabricate a holographic waveguide into the liquid crystal substrate. Mastering systems for fabricating holographic waveguides in accordance with embodiments of the invention can include a variety of features. These features include, but are not limited to: chirp for single input beam copy (near i.e. hybrid contact copy), dual chirped gratings (for input and output), zero order grating for transmittance control, alignment reference gratings, 3: 1 construction, position adjustment tooling to enable rapid alignment, optimization of lens and window thickness for multiple RKVs simultaneously, and avoidance of other orders and crossover of the diffraction beam.
Patent EP-3801652-A1 (EP)
Inventor: FAYOL DELPHINE
IPC: A61L15/40
Filed: 2019-06-06
Abstract: The invention relates to a cellularised dressing and to the method for producing such a dressing, said method preferably comprising a step of bioprinting cells.
Patent EP-3744773-A1 (EP)
Inventor: OKU KEISUKE
IPC: C08J5/18
Filed: 2019-01-21
Abstract: Provided is a method of producing a porous molded body capable of efficiently producing a porous molded body that is constituted of a hydrophilic material and has void portions densely arranged with regularity. 
     A molding device (22) produces a porous film (10) from a molding material (16) which is an emulsion. In a case where a volume of a dispersed phase (31) is X1 and a volume of a continuous phase (32) is X2, the molding material (16) has a value of X1/(X1 + X2) within a range of 0.5 or more and 0.9 or less. In the molding material (16), a specific gravity of the dispersed phase (31) is greater than a specific gravity of the continuous phase (32). The molding material (16) includes a water phase containing a curable compound as the continuous phase (32), and forms a liquid film (76) on a support (71). Thereafter, the curable compound in the liquid film (76) is cured. After curing, the dispersed phase (31) is removed.
Patent EP-3747719-A1 (EP)
Title: Vehicle control device, control method therefor, and vehicle control system
Inventor: TAKAHAMA TAKU
IPC: B62D101/00
Filed: 2019-01-07
Abstract: The present invention is directed to improving compatibility between accuracy and responsiveness for estimation of a movement trajectory of a preceding vehicle. A vehicle control apparatus calculates an approximation equation of an N-th degree function as a movement trajectory of a preceding vehicle from at least two pieces of relative position information in each of a plurality of retrospective ranges set as ranges to which the vehicle control apparatus should date back from newest relative position information in a history of a stored plurality of pieces of relative position information, and calculates a coefficient of a predetermined degree in each approximation equation. In the calculation of the coefficient of the predetermined degree, the vehicle control apparatus uses an approximation equation calculated from the at least two pieces of relative position information acquired when setting the retrospective range to the same range or a narrower range compared to when calculating a coefficient of a relatively low degree when calculating a coefficient of a relatively high degree, and uses an approximation equation calculated from the at least two pieces of relative position information acquired when setting the retrospective range to a narrower range compared to when calculating a coefficient of a lowest degree at least when calculating a coefficient of a highest degree. The vehicle control apparatus outputs an instruction according to the calculated coefficient of each degree to a steering control apparatus of a subject vehicle.
Patent EP-3843813-A1 (EP)
Inventor: DECK FRANK
IPC: A61M5/158
Filed: 2019-08-08
Abstract: A cannula cartridge (112) for receiving a cannula (114), a kit (110) comprising the cannula cartridge (112) and a method of manufacturing the cannula cartridge (112) are disclosed. The cannula cartridge 112) comprises: a) a needle unit (126) having a needle hub (128) and a needle (130) attached to the needle hub (128); b) a cannula (114), specifically a soft cannula; and c) a protective element (132). The needle unit (126) is movable within the protective element (132) from at least one first position to at least one second position and vice a versa. In the first position the needle (130) is covered by the protective element (132). In the second position the needle (130) at least partially extends from the protective element (132). In the first position a retaining member (134) of the protective element (132) engages with an engagement element (136) of the needle hub (128) by a form fit connection. The needle unit (126) is configured to be moved by an inserter (116) from the first position to the second position and back to a the first position in which the retaining member (134) again engages with the engagement element (136) of the needle hub (128). The retaining member (134) and the engagement element (136) of the needle hub (128) are configured such that a holding force of the retaining member (134) is overcome by applying forces parallel to the axis (138) of the needle (130).
Patent EP-3754571-A1 (EP)
Inventor: ZHANG TIANYI
IPC: G06Q10/06
Filed: 2019-01-29
Abstract: The present application has disclosed a method and device for generating risk control rules, the method comprising: aligning a source domain and a target domain in terms of data structures, to obtain a sample data set, wherein the sample data set comprises the source domain sample data and target domain sample data; carrying out multiple iterations with respect to the sample data set based on a preset convergence threshold, in order to obtain a weight of each sample data in the sample data set; further, determining characteristic parameter values in the preset risk control rules generation conditions according to the weight of each sample data in the sample data set; and generating risk control rules according to the preset risk control rules generation conditions and the characteristic parameter values in the preset risk control rules generation conditions, so as to be able to utilize historical data accumulated in mature service scenarios corresponding to the source domain to quickly generate risk control rules for new service scenarios corresponding to the target domain and effectively increase the efficiency of generating risk control rules.
Patent EP-3844416-A1 (EP)
Inventor: HOMMEL GÜNTER
IPC: F16D65/12
Filed: 2019-08-29
Abstract: Brake disc (10) for a disc brake, preferably of bicycles, wherein the brake disc (10) has a first and a second outer disc (22) and an inner disc (24) which is arranged between the two outer discs (22), wherein the brake disc (10) has a plurality of chambers (30) which are formed by way of recesses (26) which are arranged in the inner disc (24), and wherein the brake disc (10) has a plurality of apertures (36) which penetrate the two outer discs (22) and the inner disc (24), wherein the chambers (30) are arranged in a manner which is separated spatially from the apertures (36).
Patent EP-3766891-A1 (EP)
Title: Triaryl phosphine ligands, preparation method therefor, and use in catalysing coupling reactions
Inventor: SHI JICHENG
IPC: C07F9/50
Filed: 2019-03-28
Abstract: Provided are triaryl phosphine ligands, as shown in general formulae Ia and Ib, or a mixture thereof, and a preparation method therefor. The invention addresses the deficiencies of biaryl phosphine ligands invented by Buchwald et al. Also provided are a triaryl phosphine coordinated palladium complex, a system composed of triaryl phosphine ligand and a palladium salt or complex, and a use of the triaryl phosphine coordinated palladium complex in catalysing organic reactions, in particular a use in catalysis of coupling recations involving (pseudo)halogenated aromatic hydrocarbon as substrate.
Patent EP-3849658-A1 (EP)
Inventor: ROYON ROMAIN
IPC: A61N5/06
Filed: 2019-09-12
Abstract: The invention relates to a pulsed laser system for dermatological treatment, comprising a light source (1) suitable for emitting a light pulse beam (10) and an optical amplifier system (2) suitable for generating a laser pulse beam (20) at a first repetition frequency (F 1 ). According to the invention, the duration (d) of a laser pulse (20) is between 100 femtoseconds and 100 picoseconds, the first repetition frequency (F 1 ) is between 1 kHz and 10 GHz, each laser pulse having a quantity of energy less than or equal to 1 microjoule, and the pulsed laser system also comprises means for the temporal modulation of the laser pulse beam (20) and/or means for the spatial modulation of the laser pulse beam (20), said temporal and/or spatial modulation means being suitable for reducing the density of energy deposited on a surface to be treated and for generating a density of energy of between 0.0001 J/cm² and 0.01 J/cm².
Patent EP-3820818-A1 (EP)
Inventor: LI YUNKUI
IPC: C01B39/48
Filed: 2019-08-23
Abstract: A method of forming an AEI-type zeolite in a hydrothermal synthesis without the use of hydrogen fluoride (HF) and in the absence of any FAU zeolite Y. A gel composition formed upon using this method includes one or more sources of silica; one or more sources of alumina, one or more organic structure directing agents (OSDA); a source of alkali metal ions; and water. This gel composition is defined by the molar ratios of: SiO 2 /AI 2 O 3  16:1 to 100:1; M 2 O/SiO 2  0.15:1 to 0.30:1; ROH/SiO 2  0.05:1 to 0.20:1; and H 2 O/SiO 2   5:1 to 20:1; wherein M is the alkali metal ion and R is an organic moiety derived from the OSDA. This gel composition, after reacting at a temperature between 135°C to about 180°C for 15 hours to 168 hours forms the crystalline AEI-type zeolite having a silica to alumina ratio (SiO 2 :AI 2 O 3 ) that is greater than 8:1.
Patent EP-3941765-A1 (EP)
Inventor: EGGEBROTEN ANDREW
IPC: B60H1/00
Filed: 2019-03-18
Abstract: An HVAC module for a vehicle includes a housing. A shaft end is connected to a shaft for connection to a complementary actuator for adjusting a rotational position of the shaft to thereby adjust a position of an airflow control door in the housing. The shaft end defines an actuation axis. An externally threaded boss, coaxial with the shaft end, is defined on an exterior surface of the housing. A rotation stop post projects from the housing to engage a catch defined by the complementary actuator. The housing is to retain the complementary actuator by threading engagement with the externally threaded boss and by engagement between the rotation stop post and the catch to selectably prevent rotation of a shell of the complementary actuator about the actuation axis. The complementary actuator is interchangeably an electrically powered rotary actuator and a manually operable rotary actuator.