baber/WOPTO huggingface dataset:
Patent CA-2295858-C (CA)
Inventor: ROSE JOHN K
IPC: C12N7/04
Filed: 1998-07-10
Granted: 2011-05-10
Abstract: Des Rhabdovirus recombinés capables de réplication, ne présentant pas de gène de glycoprotéine fonctionnel et exprimant au moins un polypeptide étranger, tel qu'un récepteur cellulaire d'un autre virus dans leurs enveloppes virales, sont utiles dans le traitement de virus pathogènes. Dans un mode de réalisation, un virus de la stomatite vésiculeuse (VSD) recombiné dépourvu de son gène de glycoprotéine (G) et exprimant à la place le récepteur du VIH ainsi qu'un corécepteur, est employé dans un procédé de traitement de personnes infectées par le VIH. Le virus recombiné est inapte à l'entrée dans des cellules normales, mais il est capable de réguler l'infection à VIH dans une lignée de lymphocytes T en se répliquant dans les cellules infectées par le VIH et en les tuant.
Patent CA-2296501-C (CA)
Inventor: VELTEN JEFFREY P
IPC: C12N15/82
Filed: 1998-07-14
Granted: 2008-10-21
Abstract: A medium is disclosed that supports pollen germination and pollen tube growth in the presence of Agrobacterium, the medium comprising agarose, sucrose, NO3, MnSO4, 1-13BO3, MgSO4 and gibberellic acid.  A method is disclosed for the genetic transformation of plants and lines by a pollen-based Agrobacterim-mediated transformation.  The method comprises the steps of obtaining pollen from a first plant, applying a lawn of Agrobacteria to a solid pollen culture medium, the Agrobacterium comprising at least one heterologous gene sequence capable of being transferred to a plant cell, applying the pollen to the solid medium, allowing the pollen to germinate and grow on the medium, whereby the Agrobacterium attaches to the pollen tube or mediates transfer of the heterologous gene sequence to the germinating pollen to obtain transgenic pollen, applying the transgenic pollen to the stigma of a second plant capable of being fertilized by the pollen of the first plant, thereby fertilizing the second plant, obtaining transgenic seed from the second plant and germinating the transgenic seed to obtain a transgenic plant. The method is particularly suited for use with so-called "dry stigma" pollen.
Patent CA-2297288-C (CA)
Title: Method and apparatus for inserting/extracting sets of signals into/from a signal stream
Inventor: GOODY STEVEN H
IPC: H04J3/08
Filed: 1998-08-04
Granted: 2007-05-01
Abstract: A method and apparatus in an optical network unit for identifying signals for a set of communication devices in a signal stream having signals for a number of different sets of communication devices. Each optical network unit ONU (335) includes a common control unit CCU (350) which uses a content addressable memory CAM for identifying sets of signals that need to be extracted from the signal stream and transmitted to a first set (392, 394, 396, 398) of communication devices; and identifying time periods for inserting sets of signals from a first set of communication devices into a signal stream.
Patent CA-2299677-C (CA)
Inventor: FRACE A MICHAEL
IPC: A61K39/42
Filed: 1998-08-06
Granted: 2011-07-26
Abstract: L'invention concerne une technique qui permet d'augmenter l'expression recombinante et la solubilité du polypeptide M2 du virus grippal A, ledit virus renfermant des acides nucléiques qui codent pour une protéine M2 modifiée dans laquelle des domaines transmembranaires et d'autres domaines hydrophobes ont été délétés; des polypeptides purifiés codés par lesdits acides nucléiques, qui sont immunogènes et moins hydrophobes que la protéine M2 pleine longueur; des vaccins renfermant des variants de M2 exprimés dans des cellules procaryotes; des techniques qui permettent de prévenir l'infection par le virus grippal A au moyen de vaccins renfermant des variants de M2; et des anticorps produits contre les variants de M2, ainsi que leur utilisation dans le diagnostic et le traitement des infections par le virus grippal A.
Patent CA-2301539-C (CA)
Title: Method of making high density arrays
Inventor: DAWSON ELLIOTT P
IPC: C40B40/18
Filed: 1998-05-19
Granted: 2003-06-17
Abstract: A method of producing high density arrays of target substances comprising th e step of sectioning a bundle of target-strands, wherein the target-strands comprise the target substances, and wherein the sectioning results in a plurality of high density arrays. Additionally, the method can include additional steps, such as stabilizing the target-strands or bundles, incorporating one or more additional materials into the high density array, and interrogating the high density array. Also, a high density array produce d according to the method.
Patent CA-2308482-C (CA)
Title: Optical communication network
Inventor: QUAYLE JOHN ALAN
IPC: H04B10/272
Filed: 1998-10-29
Granted: 2007-06-12
Abstract: A communications network is provided comprising an optical waveguide (1) to which is connected a head-end station (2) and at least one optical network unit (ONU) (3), an ONU (3) providing an interface to the communications system for connected user equipment (5).  Data received by an ONU (3) from connected user equipment (5) are stored in a buffer (13) prior to transmission to the head-end station (2). The head-end station (2) is arranged to implement, in conjunction with the ONUs (3), a demand-assignment protocol for the transfer of data upstream from the ONUs (3) to the head-end station (2) according to which an ONU (3) demands usptream capacity based upon a prediction of its future capacity requirements, calculated using at least one record of earlier granted capacity by the head-end station (2) and at least one measurement of a quantity of data awaiting transmission to the head-end station (2) in the buffer (13) of the ONU.
Patent CA-2310004-C (CA)
Inventor: LOEFFLER DONALD ROBERT
IPC: A61B18/14
Filed: 1998-11-13
Granted: 2007-01-09
Abstract: A bipolar electro-surgical instrument (10) can apply a large closure force between its jaws (15, 16) without damaging the small yoke assembly. The instrument comprises a first jaw having a first flange with a first slot, and a second jaw having a second flange with a second slot. The first and the second jaws are located at a distal end of the instrument. They comprise an electrically conductive material for conducting bipolar electro-surgical current therebetween. A yoke is attached to a pushrod positioned to electrically insulate the first flange from the second flange. The yoke has a first side facing the first.flange, and a second side facing the second flange. The yoke further comprises a first shoulder, and a second shoulder; a first pin located on the first side, and movably engaged with the first slot; a second pin located on the second side, and movably engaged with the second slot. The first slot and second slot are shaped such that an angle subtended by the first and second jaws decreases with distal motion of the pushrod with first and second cul-de-sacs positioned respectively in the first and second slots to relieve shear stresses on the first and second pins, approximately when the first and second shoulders respectively engage the first and second flanges to provide a closure force between the first and second jaws.
Patent CA-2312188-C (CA)
Title: Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation
Inventor: GILLIES STEPHEN D
IPC: C07K14/54
Filed: 1998-12-08
Granted: 2010-06-29
Abstract: Disclosed are methods for producing fusion proteins with the heterodimeric cytokine, interleukin-12. In order to insure that the proper ration of fused and non-fused subunits are obtained in the fusion protein, a specific stepwise approach to genetic engineering is used. This consists of first expressing the non-fused p40 IL-12 subunit in a production cell line, followed by or simultaneously expressing in the same cell, a second recombinant fusion protein consisting of the fused polypeptide linked by a peptide bond to the p35 subunit of IL-12. Molecules containing the p35 fusion protein cannot be secreted from the transfected mammalian cell without first complexing in a one to ratio with the p40 subunit, thus ensuring the production of active heterodimeric fusion proteins.
Patent CA-2314317-C (CA)
Title: Optical fiber cable with single strength member in cable outer jacket
Inventor: FITZ JON
IPC: G02B6/44
Filed: 2000-07-21
Granted: 2010-09-28
Abstract: An optical fiber cable has a core with a bore which loosely contains optical fibers and includes a single strength member embedded in an outer jacket which surrounds the core. The strength member allows for relative ease of bending of the cable in directions other than the bending directions in the plane of minimum bending energy for the cable, such as bending in the plane of maximum bending energy (MAX-BP) for the cable, and provides that the neutral surface associated with bending of the cable in the MAX-BP is outside the bore core and within the outer jacket. The single strength member furthermore provides tensile strength and antibuckling properties to the cable during storage and in expected installations, including an aerial installation. The outer jacket is releasably coupled to the core to provide ease of access to the optical fibers contained within the core bore.
Patent CA-2317323-C (CA)
Title: Oligomeric and polymeric telechelics
Inventor: MELCHIORS MARTIN
IPC: C07D211/00
Filed: 2000-09-01
Granted: 2009-11-24
Abstract: The invention relates to a new process for the preparation of functionalized telechelics based on vinyl polymers, the telechelics prepared in this way and their use in the plastics, fibers or coating sector.
Patent CA-2319814-C (CA)
Title: Composition de revetement pour electrodeposition cationique
Inventor: SUGITA MASARU
IPC: C09C3/06
Filed: 1999-01-28
Granted: 2008-03-11
Abstract: L'invention concerne une composition de peinture pour électrodéposition cationique renfermant: A) une résine pour électrodéposition cationique; B) un composé contenant un métal choisi parmi le bismuth, le lanthane, et le molybdène; et C) un hydroxyde métallique représenté par la formule générale suivante: M(1-x)Alx(OH)(2+x) mH2O (dans laquelle M représente Mg ou Zn; et x et m sont des valeurs correspondant aux rapports: 0</=x</=1 et 0</=m<2). La composition de cette invention permet de former des films de revêtement qui exercent un excellent effet anticorrosion sur des tôles d'acier non traitées, et présentent un aspect extrêmement lisse sans pour autant utiliser de substances nocives, par exemple des composés de plomb ou de chrome.
Patent CA-2332964-C (CA)
Inventor: FUKUNAGA TETSUYA
IPC: B01J37/02
Filed: 1999-06-04
Granted: 2007-07-24
Abstract: L'invention concerne un catalyseur qui comprend un support de zirconium portant un ruthénium, et un catalyseur qui comprend un support d'oxyde inorganique portant un zirconium et un ruthénium. Ces catalyseurs peuvent être utilisés pour réaliser une réaction de reformage adiabatique à forte conversion, ou une réaction de reformage au moyen d'un dioxyde de carbone à rendement de monoxyde de carbone élevé et accumulation de coke réduite, tout en maintenant une activité catalytique stable pendant une longue période.
Patent CA-2334540-C (CA)
Inventor: SANO YOSHIKAZU
IPC: C09D11/10
Filed: 2000-05-02
Granted: 2007-07-31
Abstract: This invention provides a process for preparing a phenol-modified rosin ester, the process comprising the step of reacting rosin with phenol, formaldehyde and polyhydric alcohol, the process being characterized in that rosin or a polyhydric alcohol ester of rosin is reacted with a resol phenol resin prepared in the presence of a volatile base catalyst, the invention further provides a phenol-modified rosin ester prepared by the above-mentioned process, and the invention also provides a binder for printing inks which contains the phenol-modified rosin ester and further provides a printing ink containing the binder for printing inks.
Patent CA-2336273-C (CA)
Inventor: HILLEARY THOMAS N
IPC: G08B29/12
Filed: 2001-03-01
Granted: 2009-05-26
Abstract: To reduce or eliminate difficulties inherent in manual reporting of signal light failures, especially at remote railroad grade crossings, there is provided, in one embodiment of the present invention, a system for monitoring failure of a lighted signal that includes lighting configured to flash during a predetermined alarm condition. The system includes a power supply configured to power the lighting during the predetermined alarm condition and to provide a timing signal indicative of power being applied to the lighting; a detector/transmitter responsive to the timing signal to detect lighting parameters when the lighting is flashed on to generate a signal indicative of the lighting parameters and to generate a signal indicative of the lighting parameters; and a receiver/concentrator responsive to the signal indicative of the lighting parameters to generate a signal indicative of predetermined fault conditions of the lighting.
Patent CA-2338182-C (CA)
Inventor: BOULET D AURIA STANISLAS
IPC: F16L55/17
Filed: 1999-08-12
Granted: 2007-07-10
Abstract: The invention concerns a device for stopping a leak in a pipe having at least one crack (12, 12'), comprising an elastomer sheet (14) applied against the crack with a force applicator (16) and a clamping mechanism (20, 22) arranged around the pipe for applying a force on the force applicator. Said force applicator comprises shearing elements (40, 42) preferably consisting of a first group of rigid parallel partitions (40) and a second group of parallel partitions (42) arranged perpendicularly to the partitions of the first group, said partitions being arranged perpendicularly to the pipe and applying shearing efforts on the elastomer sheet on the site of the crack, forcing the elastomer to be deformed so as to match the shape of the crack, thereby stopping it.
Patent CA-2353814-C (CA)
Title: A laundry appliance with load balancing system
Inventor: RHODES DAVID CHARLES
IPC: D06F34/16
Filed: 1999-12-21
Granted: 2007-04-17
Abstract: A laundry appliance comprising a perforated rotatable drum (11) for dehydrating a clothes load, a substantially rigid, free standing drum support means supporting the drum (11) rotatably but non-translatably in relation to a support surface, driving means (39, 40) for rotating the drum (11) at speed thereby dehydrating the load, and a system for compensating for imbalances of the drum (11) and any load carried therein during dehydration of the load.
Patent CA-2355516-C (CA)
Inventor: NAGY LOUIS A
IPC: B62D25/14
Filed: 2001-08-17
Granted: 2009-05-05
Abstract: A cross car structure member including a beam comprising a hollow extended aluminum metal tube extending across the vehicle between the vehicle pillars, preferably, with the interior of the tube being used as a heating, ventilating and air conditioning duct.
Patent CA-2359298-C (CA)
Inventor: CARTY WILLIAM E
IPC: B60D1/24
Filed: 2001-10-18
Granted: 2010-02-16
Abstract: A trailer having a tongue that defines a longitudinal axis and includes a coupler portion. The coupler portion of the tongue can pivot relative to the longitudinal axis, thereby forming an angle between the coupler portion and the longitudinal axis. In a preferred embodiment, the tongue includes a breakaway coupler assembly. The breakaway coupler assembly includes the coupler portion having a distal end adapted to engage a towing vehicle, and a flex-joint pivotally engaged with the coupler portion. This allows the coupler portion to pivot relative to said flex-joint when a predetermined force is placed on the flex-joint, such as in a jack-knife situation.
Patent CA-2360287-C (CA)
Inventor: HOLM PER
IPC: A61J3/10
Filed: 2001-02-28
Granted: 2003-09-09
Abstract: The present invention relates to the crystalline base of the well known antidepressant drug citalopram,1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile, formulations of said base, a process for the preparation of purified salts of citalopram, such as the hydrobromide, using the base, the salts obtained by said process and formulations containing such salts.
Patent CA-2364732-C (CA)
Title: Binary foaming drain cleaner
Inventor: CHUNG JESSICA Y
IPC: C11D1/90
Filed: 2001-12-06
Granted: 2012-06-26
Abstract: A composition is provided comprising two liquids which are separately maintained prior to forming an admixture during delivery to a surface to be treated, whereupon the admixture generates a foam sufficient for cleaning efficacy and stability. A first liquid preferably includes a hypohalite, or a hypohalite generating agent and a second liquid preferably includes a peroxygen agent. The first liquid is thickened to a specified rheology, resulting in the generation of a highly effective foam. As the two liquids are initially separated, the hypohalite generating agent can be maintained in an environment free of peroxygen agent and otherwise conducive to their cleaning activity and stability up to the time of use. When the two liquids are allowed to mix, for example, by simultaneously pouring into a drain, the hypohalite and peroxygen react to liberate oxygen gas. As foam generation occurs, the escaping gas contacts surfactant in the solution, and creates foam which expands to completely fill the drain pipe. The expanded foam contains an excess of the hypohalite, which acts to clean the drain.
Patent CA-2365281-C (CA)
Title: Human antibodies that bind human il-12 and methods for producing
Inventor: VELDMAN GEERTRUIDA M
IPC: A61P37/06
Filed: 2000-03-24
Granted: 2009-08-04
Abstract: Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies , or antibody portions, of the inveniton are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject sufferin g from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.
Patent CA-2371625-C (CA)
Inventor: FRYDMAN BENJAMIN
IPC: A61K47/48
Filed: 2000-04-27
Granted: 2012-04-17
Abstract: L'invention concerne de nouveaux analogues de polyamine à conformation restreinte ainsi que des compositions renfermant ces nouveaux analogues de polyamine. Cette invention concerne également des méthodes d'utilisation de ces nouveaux analogues de polyamine pour traiter des maladies comme le cancer, et des méthodes permettant un apport spécifique de ces analogues à des cellules tumorales, par liaison covalente entre lesdits analogues de polyamine et des composés de porphyrine, avec de nouveaux conjugués de polyamine-porphyrine covalents.
Patent CA-2373330-C (CA)
Inventor: NEWELL WILLIAM
IPC: G16B30/10
Filed: 2000-05-19
Granted: 2009-12-22
Abstract: The present invention provides methods for detecting known blocks of functionally aligned protein sequences in a test nucleic acid sequence in a test nucleic acid sequence, based on the total number of base matches for the variety of possible tags.  This method reverse-translates common protein alignments to nucleic acid profiles, using recently tabulated codon frequencies. The method then performs a search for the known nucleic acid profiles by obtaining the correlation of different based between a test nucleic acid sequence and the known nucleic acid profile. This is efficiently achieved in the frequency domain by use of a Fast Fourier Transform.
Patent CA-2374446-C (CA)
Title: Process for making dyes of high purity
Inventor: MOLINSEK LOUIS
IPC: C07C309/46
Filed: 2000-05-25
Granted: 2007-03-13
Abstract: An aromatic amino sulfonic acid compound is purified by a process including steps of: (a) dissolving the aromatic amino sulfonic acid compound in aqueous medium having a basic pH; (b) acidifying the aqueous medium with acetic acid to precipitate the aromatic amino sulfonic acid compound; and (c) removing the precipitated aromatic amino sulfonic acid compound from the aqueous medium. Using acetic acid in the process results in removal of more impurities and undesirable sulfate and chloride salts to provide an improved material for synthesizing dyes and pigments.
Patent CA-2375143-C (CA)
Inventor: HANSEN DAVID R
IPC: B41J29/38
Filed: 2001-05-16
Granted: 2007-07-24
Abstract: A printing system is disclosed for printing a plurality of jobs in a system, which includes a plurality of job preparation stations (204). Each of the jo b preparation stations is used to convert the documents into ready for printer file format and to generate an electronic job ticket (438) that represents global document features. Each job preparation station includes a set of defined attributes for that station, such as operator skill level and/or printer experience. A job allocator receives the set of defined station attributes for each of the job preparation stations and distributes printing jobs to each of the job printing stations based on the defined station attributes of the job preparation stations.
Patent CA-2385098-C (CA)
Inventor: HSU YA-WEI
IPC: E06B9/32
Filed: 2002-05-06
Granted: 2007-07-10
Abstract: An electromagnetic clutch-controlled electric blind is constructed to include a blind body formed of a headrail defining a receiving chamber, a set of slats, and a bottom rail, a power drive, the power drive including a reversible motor and electromagnetic clutch means connectable to the motor, an amplitude modulation set coupled to the motor for rotation with the motor to lift/lower the slats to the desired elevation, a frequency modulation set coupled to the motor through the electromagnetic clutch means and adapted for controlling tilting angle of the slats.
Patent CA-2386216-C (CA)
Inventor: HARDY GREGORY J
IPC: B65D81/127
Filed: 2000-10-05
Granted: 2006-06-13
Abstract: L'invention concerne un carton (10) de suremballage servant à emballer une boîte d'expédition (12) primaire, qui comprend une bande d'emballage (20) pourvue de panneaux latéraux (22, 24, 26, 28) interconnectés et d'un panneau de verrouillage, une ou plusieurs garnitures (80) de rembourrage fixées aux panneaux latéraux (22, 24, 26, 28), et des éléments de blocage pour bloquer la bande d'emballage (20) autour d'au moins une partie de la boîte d'expédition (12) primaire. Un procédé d'emballage de boîte d'expédition (12) primaire comporte les étapes consistant à: prévoir une bande d'emballage (20) rembourrée pourvue d'éléments (38) de blocage, enrouler la bande d'emballage (20) autour d'au moins une partie de la boîte d'expédition (12) primaire et faire coopérer les éléments (38) de blocage.
Patent CA-2394572-C (CA)
Title: Fusion protein having enhanced in vivo activity of erythropoietin
Inventor: LEE DONG-EOK
IPC: C07K14/505
Filed: 2002-07-24
Granted: 2007-08-14
Abstract: The present invention relates to a fusion protein having enhanced in vivo activity of erythropoietin wherein a carboxy terminal peptide fragment of thrombopoietin is fused with the carboxy terminal of human erythropoietin. This fusion protein has highly enhanced in vivo half-life due to increased carbohydrate content without loss of the inherent activity of erythropoietin, and does not cause any antigenicity when applied to the human body.