baber/WOPTO huggingface dataset:
Patent WO-2014153254-A9 (WO)
Title: Compositions and methods to control insect pests
Inventor: HU XU
Filed: 2014-03-14
Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a  Diabrotica  plant pest, decrease the expression of a target sequence in the pest. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: disclosed herein, (but not including the forward and reverse primers.) or active variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest (i.e., has insecticidal activity). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
Patent WO-2015051277-A9 (WO)
Title: Procédé et appareil permettant d'obtenir des couches de finition à haute densité
Inventor: HARKNESS IV SAMUEL D
IPC: C23C8/00
Filed: 2014-10-03
Abstract: Cette invention concerne un système de dépôt conçu de façon que des cibles conductrices de composition similaire se trouvent à l'opposé l'une de l'autre. Le système est aligné parallèlement au substrat, qui se trouve à l'extérieur du plasma obtenu qui est largement confiné entre les deux cathodes. Un cage "plasma" est formée dans laquelle les atomes de carbone entrent en collision avec des électrons en accélération et s'ionisent fortement. Les électrons sont piégés à l'intérieur de la cage plasma, tandis que les atomes de carbone ionisés se déposent sur le surface du substrat. Comme les électrons sont confinés dans la cage plasma, le substrat n'est sujet à aucun dommage ou chauffage. De plus, les atomes d'argon, qui sont utilisés pour l'allumage et l'entretien du plasma et pour la pulvérisation cathodique des atomes de carbone à partir de la cible, n'atteignent pas le substrat, de façon à éviter d'endommager le substrat.
Patent WO-2015073222-A9 (WO)
Title: Normalisation de la circulation entéro-hépatique chez des animaux pourvus d'un foie humanisé chimérique
Inventor: GROMPE MARKUS
IPC: A61P1/16
Filed: 2014-10-30
Abstract: La présente invention concerne des procédés de normalisation de la production d'acides biliaires chez une souris greffée avec des hépatocytes humains par l'administration de FGF19 humain. Elle concerne également un animal hôte transgénique, tel qu'une souris, qui exprime FGF19 humain et qui présente une production normalisée d'acides biliaires lorsqu'elle a été greffée avec des hépatocytes humains.
Patent WO-2019089080-A9 (WO)
Inventor: TRABER PETER G
IPC: C07H5/08
Filed: 2018-05-11
Abstract: Selon des aspects, la présente invention concerne de nouveaux composés synthétiques ayant une affinité de liaison avec des protéines de galectine pour le traitement de troubles de la résistance systémique à l'insuline.
Patent WO-2020023595-A9 (WO)
Inventor: LIVIA CHRISTOPHER
IPC: C12N15/11
Filed: 2019-07-24
Abstract: A circular RNA molecule generally includes at least one coding region and an internal ribosome entry site (IRES) operably linked to the coding region. The RNA may be more resistant to digestion by an RNA endonuclease that a linear form of the circular RNA. In another aspect, a polynucleotide generally includes a transcription unit and a promoter operably linked to the transcription unit. The transcription unit includes a circularizing element, at least one coding region and an internal ribosome entry site (IRES) operably linked to the coding region. When transcribed by a cell, the transcribed RNA forms a circular RNA molecule.
Patent WO-2021150581-A9 (WO)
Title: Immunologically optimized botulinum toxin light chain variants
Inventor: GRISWOLD KARL E
IPC: C07K14/195
Filed: 2021-01-20
Abstract: Deimmunized botulinum toxin light chain (e.g., botulinum toxin serotype A light chains (BoNT/A-LC)) or fragments thereof are provided. Methods for treating or preventing diseases or disorders comprising administering to a subject a deimmunized botulinum toxin light chain (e.g., BoNT/A-LC) are provided.
Patent WO-2022261182-A9 (WO)
Inventor: KENT THOMAS
IPC: A61K47/00
Filed: 2022-06-08
Abstract: A method of treating a Down syndrome ( DS ) subj ect with functional or at risk of decline of organ systems associated with accelerated aging due to over-production of H 2 S is disclosed. That method contemplates administering a pharmaceutical composition containing a H 2 S-reducing ef fective amount of hydrophilic polymer-substituted oxidi zed carbon nanoparticles ( OCNPs ) and an optional potentiating amount of lipoic acid or dihydrolipoic acid dissolved or dispersed in a physiologically acceptable diluent to the subj ect. The pharmaceutical composition can be administered parenterally as a liquid or per os as a solid or liquid.
Patent CS-254206-B1 (CS)
Inventor: ONDRUS IMRICH
IPC: C07B39/00
Filed: 1986-01-02
Abstract: Riešenie sa týká reaktora pre chloráciu
uhíovodíkov v kvapalnej fáze bez nútenej
cirkulácie reakčného produktu.
Reaktor je tvořený spojitou nádobou, v
ktorej ramenách, kde poměr výšky : priemeru
je 6 až 10, sú rúrkovnicové systémy
oddefujúce reakčnú zmes od chladiaceho
média, pričom přívod vstupných surovin je
umiestnený pod spodným okrajom rúr.kovnicového
systému, s výhodou umiestneného
súose so spodnou časťou spojitej nádoby a
ramená spojitej nádoby nad rúrkovnicovým
systémom sú navzájom přepojené a aspoň
na jednom ramene je napojený odplyn a
přepad pre produkt je situovaný spodným
okrajom nad hornou úrovňou prepojenia ramien.
Patent IE-53927-B1 (IE)
Title: Improvements in or relating to a carrier
IPC: A47J45/07
Filed: 1983-01-10
Abstract: A container encircling frame with opposed pairs of resiliently deformable straps extending therefrom. Each pair of straps mounts an elongated handle element transversely across the outer ends thereof, the two handle elements, upon a releasable interlocking thereof, defining a single handle or hand grip. Each handle element includes a vertical ribbed panel, with a laterally spaced lip defining a recess for the panel of the other handle element. Interlocking is effected through releasably engageable detents and projections on the panels and lips.
Patent CS-248115-B1 (CS)
Inventor: MIHALKOVIC KOLOMAN
IPC: B23K35/22
Filed: 1983-02-03
Abstract: Účelom riešenia je dosiahnuť vysokú tvrdost
a vysokú odolnost návarového kovu
proti abrázii kombinované] rázmi.
Účinok riešenia sa dosiahne tým, že náplň
rúrkového drotu obsahuje 0,4 až 3,2 %
hmot. fluórokremičitanu sodného, 34,8 až
65,2 % hmot. vysokouhlíkatého· ferochrómu,
0,1 až 6,4 % hmot. vysokouhlíkatého feromangánu
alebo mangánu, 0,1 až 4,3 % hmot.
ferosiiícia, 0,5 až 25,5 % hmot. železného
prášku, 0,1 až 3,6 % hmot. grafitu alebo
silikokarbidu, 10,5 až 20,4 % hmot. ferobóru,
0,3 až 10,5 °/o hmot. ferotitánu, pričom
súhrn obsahov ferobóru a ferotitánu je ohraničený
od 15,6 % hmot. do 27,7 % hmot.
Patent DK-172403-B1 (DK)
Inventor: BROECHMANN OLE FLEMMING
IPC: B25H1/16
Filed: 1996-03-15
Granted: 1998-05-18
Abstract: A hydraulic lifting-lowering-system for a working table, a couch or lying furniture or another heavy object allows the height level or position to be frequently adjusted or changed. The system includes a predetermined amount of hydraulic fluid, a hydraulic fluid accumulator, the fluid pressure of which on the hydraulic fluid side is adjustable, a single acting hydraulic cylinder with two end caps, a piston pressure chamber and a piston rod which, via a piston rod sealing ring, extends sealingly out through the one end cap of the cylinder. The piston pressure chamber is pressure fluid connected to the hydraulic fluid side of the accumulator. The hydraulic cylinder is of the plunger piston type, and the cylindric tube of the hydraulic cylinder is slideably and telescopically mounted in a cylindrical guiding tube, which surrounds the piston rod in its entire length and is rigidly secured to the one end of the piston rod via a cross plate or similar construction part. Thus, a simple, stable and reliable system is achieved without the need for crank handles, and by which new system the force applied from the plunger piston rod will be essentially constant in all positions of the piston rod at a given load, seeing that the operational manual force necessary for height adjustment of the heavy object becomes low.
Patent DK-173329-B1 (DK)
Inventor: QUERCIA RICCARDO
IPC: A61M39/00
Filed: 1994-05-11
Granted: 2000-07-24
Abstract: An apparatus (10) for draining fluids, for example, from a chest or pleural cavity, includes a collection chamber (12) for collecting fluids through an inlet port (36) for entry of the fluids. Also included is a dry or waterless suction control chamber (16) in fluid communication with the collection chamber (12) for regulating the degree of vacuum imposed in the collection chamber. If desired, a seal chamber (14) can also be provided between the dry suction control chamber (16) and the collection chamber (12) so as to prevent any ambient or atmospheric air from passing into the collection chamber. The suction control chamber (16) has a first inlet (60) which is coupled to a suction source and second inlet (74) communicates with the ambient. A waterless regulator (72) is provided for regulating the degree of suction imposed in the collection chamber (12) at a plurality of predetermined preset levels of suction. This regulator is positioned between the suction inlet (6) and the ambient inlet (74). The suction control chamber (16) also has at least a visual indicator (152) disposed between the regulator (72) and the suction inlet (60) for providing immediate confirmation of proper operation of suction in the collection chamber.The present invention also includes an apparatus (118) for supporting a housing from a support (120) including a bracket member (116) formed of opposed walls (272, 274) and having a post member (276) extending between the walls, one of the walls (272) capable of being positioned on the housing; and a hook member (278) having one rotatably secured about the post member (276) for selective rotational movement from a first storage position to a second hanging position, the other end of the hook member (278) being configured for engagement with the support (120), the one end of the hook member (278) and the bracket (116) being configured and dimensioned so that the hook member (278) remains locked in the hanging position.Also contemplated within the present invention is a device (159) for retaining tubing (146) under compression so as to provide self-sealing capability of the tubing during sampling or injection procedures.
Patent DK-174892-B1 (DK)
Inventor: BOISSONEAULT ROGER
IPC: A61K31/57
Filed: 1987-02-26
Granted: 2004-01-26
Abstract: Medication and pharmaceutical composition containing at least one synthetic estrogenic compound and at least one progestogenic compound for the treatment of estrogen deficiency.
Patent IE-42409-B1 (IE)
Title: Acetylene derivatives of amino acids
IPC: C07C239/00
Filed: 1976-01-23
Abstract: 1467138 Alkynoic acid derivatives RICHARDSON-MERRELL Inc 26 Jan 1976 [18 March 1975] 02855/76 Heading C2C Racemic and optically active compounds of the general formula (R = H, C 2-5 alkylcarbonyl or alkoxycarbonyl, COCH(NH 2 )R 10 ; R 2 = OH, C 1-8 alkoxy, C 1-4 alkylamino, NHCHR 4 COOH; R 4,10 =H, C 1-4 alkyl, benzyl, p-hydroxybenzyl; A=(CHR 1 ) n , CH=CH; R 1 = H, C 1-4 alkyl, phenyl optionally substituted by halogen, C 1-4 alkyl, C 1-4 alkoxy; n=1-5), the lactams of the compounds in which A=(CH 2 ) 2,3 and R=H, and their salts are prepared by standard methods, e.g. reacting CH 3 ) 3 SiC#CCH 2 N=CHPh with a haloester or unsaturated ester in the presence of a base to introduce the R 2 COA group followed by removal of the protecting groups and, optionally, introduction of an R substituent, replacement of R 2 by a different group, dehydration to a lactam, resolution and/or salt formation. The preparation of 3-benzylideneiminoprop-1- yne is described. The above compounds are useful in the treatment of disorders of the central nervous system and as hypothermic agents, myorelaxants, cholinergic agents, antibacterial agents, anticonvulsants, analgesics, anorectics, tranquillizers and sedatives. They may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
Patent IE-44483-B1 (IE)
Title: Improvements in or relating to carbamyltriazole insecticides
IPC: A01N47/38
Filed: 1977-03-01
Abstract: 1508757 Carbamyltriazole insecticides GULF OIL CORP 1 March 1977 08477/77 Heading C2C Novel carbamyltriazole compounds of the general formula wherein R is 2-propynyl, allyl, 2-bromoallyl, 2 - chloroalkyl, 2 - methylallyl, 1 - methylallyl or 2,3,3 - trichloroallyl, and R1 is t - butyl, propyl, cyclopropyl or isopropyl are useful as insecticides. The novel compounds may be prepared by several conventional processes.
Patent IE-33059-B1 (IE)
Title: Improvements in or relating to data transmission systems
IPC: H04B14/02
Filed: 1969-04-17
Abstract: 1,257,308. Multiplex radio signalling. GENERAL ELECTRIC CO. Ltd. 17 April, 1969 [17 April, 1968], No. 18129/68. Heading H4L. In a signalling system in which data is transmitted by phase modulation of a carrier wave, an auxiliary or supervisory signal is-transmitted by frequency modulation of said carrier, the highest frequency component of the -auxiliary signal being of lower frequency than the data bit rate, such that the maximum phase shift of the carrier due to the frequency modulation during any one pulse interval of the data transmission is much less than the minimum step phase shift utilized in transmitting the data. Transmitter, Fig. 2.-Data signals in dibit form, from sources 5 are modulated on to four carrier waves by respective phase modulators 4 providing four -possible phase shifts of -the carrier, the carriers being derived from sources 6 via frequency-modulators 7 and filters 8. Auxiliary signals from sources 9 are supplied to the modulators 7 so that one auxiliary signal is modulated on each carrier. Alternatively one auxiliary signal may be transmitted as a differential modulation of a pair of carriers. The outputs of the phase modulators 4 are supplied via filters 10 to an amplifier 11 where they are combined for transmission by radio. Repeater, Fig. 3.-Each aerial 12 is arranged to receive -and transmit both vertical -and horizontally polarized signals so that each repeater can transmit and receive two groups of four carrier frequencies in either direction. Received signals are supplied via a circulator 13 and filter 14 to a mixer 15, the output of the mixer 15 being supplied via an I.F. amplifier to a mixer 17 providing a signal for retransmission via filter 21, amplifier 22 and circulator 23. An oscillator 18 provides local oscillations for the mixer 17 and after mixing at 19 with output of an oscillator 24 provides local oscillations for the mixer 20. An auxiliary signal may be transmitted to the terminal station by frequency modulating the output of oscillator 24 so that it is modulated on all four carriers. Receiver, Fig. 4.-The auxiliary signals are recovered frequency-multiplying all the carrier signals by four so that the phase-shifts representing the data signals become multiples of a complete cycle and have no effect. The resulting signals are supplied via filters 26 to frequency dividers 27 where the original carrier frequencies, modulated in frequency but without the phase shift modulation, are recovered and are supplied to control the frequency of oscillators 28. Low frequency signals carrying the frequency modulation may be derived by mixing the output of each oscillator 28 with unmodulated carrier signals or in the case of differentially modulated carriers by supplying the differentially modulated carriers to a mixer 33 and applying the output of the mixer to a frequency discriminator 34. Synchronous detectors 29 recover the data signals which are regenerated at 30 and separated into individual pulse trains at 31.
[GB1257308A]
Patent IE-60113-B1 (IE)
Title: Woven elasticated material
IPC: D03D15/56
Filed: 1987-03-06
Abstract: Woven material for waistbands are elasticated by inclusion of elastane in the weave, characterised in that bare elastane is used, and the slippiness of the bare surface of the elastane is counteracted by the use of a weaving pattern such that the elastane interlocks with the wefts of the woven material, thereby preventing or reducing slip back. Alternatively a flexible bonding agent may be added to lodge in the interstices and prevent slip back either by application to the warps or, after weaving, to the finished fabric. An aqueous solution of surfactants and polymeric material may be mixed with polyvinyl acetate resin (10 grams/litre), water and softener.
Patent IE-45127-B1 (IE)
Title: Blood filter
IPC: A61M5/165
Filed: 1977-03-25
Abstract: A filter for blood and the like including a housing defining an inlet for fluids to be filtered, and an outlet for filtered fluid, plus a stack of filter pads of thermoplastic fibers positioned within the housing. According to one aspect of this invention, the stack of pads is joined together at their periphery by a heat seal to form an integral filter unit, while, typically, the stack is joined to the housing at such periphery by a second seal. In another aspect of this invention, the fluid inlet is positioned adjacent a first pad of the stack and the fluid outlet is adjacent a last pad of the stack, the diameter of the fibers of the last pad being smaller than the diameter of the fibers of the first pad, typically with the fiber diameter of intermediate pads generally decreasing from pad to pad in the direction of the last pad.
Patent IE-34588-B1 (IE)
Title: Improvements in or relating to penicillin esters
IPC: C07D499/32
Filed: 1970-05-19
Abstract: Penicillin esters (I) are produced by (a) contacting a salt of penicillanic acid with a chloroformic or bromo-formic acid with an alcohol or phenol (pref. 2,2,2-trichloroethanol), in an inert, anhydrous organic solvent, pref. at -20 degrees to + 30 degrees C, and in the absence of a substantial excess of base, until a mixed anhydride (II) is obtained, (b) decarboxylating II by contact with a weak tertiary base (pref. at -10 degrees to + 30 degrees C), to obtain I, and the alcohol or phenol I are intermediates for penicillins and cephalosporins.
[FR2048490A5]
Patent LU-93240-B1 (LU)
Inventor: MIZIRAKCI MUSTAFA
IPC: B65H75/22
Filed: 2016-02-26
Granted: 2017-03-27
Abstract: L'invention, sur laquelle le fil qui est un materiau de construction est enroule et qui permet que le fil soit a nouveau decharge sans utiliser d'equipements ou de main d'ceuvre supplementaires et sans endommager le fil, comprend essentiellement au moins un corps (2) qui permet que le fil soit maintenu ensemble en etant enroule autour du corps et au moins une bague (3) qui maintient les parties de bord du corps ou les parties formees par decoupe du cylindre situe sur le corps (2). Le tube d'enroulement de fil (1) de l'invention ne requiert pas I'utilisation d'equipements supplementaires pour decharger le fil autour du tube, et il evite I'operation d'ouvriers et de machines additionnels et il vise ainsi a diminuer le cout et la perte de temps, et il evite egalement que le fil enleve lors de la decharge ne soit mis au rebut
Patent MA-31427-B1 (MA)
Title: Polymeres contenant un nanogel de sels metalliques
Inventor: HELLING GUENTER
Filed: 2009-12-01
Abstract: L'INVENTION CONCERNE UN PROCÉDÉ DE PRODUCTION DE DISPERSIONS AQUEUSES, DE PRODUITS INTERMÉDIAIRES SOLIDES ET DE PRODUITS DE MATIÈRES PLASTIQUES RÉSISTANT À L'EAU, CONTENANT DES NANOGELS DE SELS MÉTALLIQUES, PERMETTANT DE FABRIQUER DE MANIÈRE SIMPLE DE NOUVEAUX PRODUITS À PRINCIPES ACTIFS RÉPARTIS DE MANIÈRE HOMOGÈNE, QUI PRÉSENTENT PAR EXEMPLE UNE ACTION ANTIMICROBIENNE OU DE BARRIÈRE ET/OU POSSÈDENT UNE CAPACITÉ D'ABSORPTION, PAR EXEMPLE VIS-À-VIS DE L'OXYGÈNE, DE L'HUMIDITÉ, DES COMPOSÉS CHIMIQUES, EN PARTICULIER GAZEUX, OU D'UN RAYONNEMENT ÉLECTROMAGNÉTIQUE OU RADIOACTIF.
Patent MA-31672-B1 (MA)
Inventor: D AOUST MARC-ANDRE
IPC: C12N15/82
Filed: 2010-01-12
Abstract: La présente invention concerne un procédé permettant de synthétiser une protéine d'intérêt dans une plante ou une partie de plante. Le procédé décrit comprend l'introduction d'une ou de plusieurs séquences d'acide nucléique codant une protéine d'intérêt liée fonctionnellement à une région régulatrice obtenue à partir d'un gène photosynthétique qui est actif dans la plante de façon éphémère. La plante est alors maintenue dans des conditions qui permettent l'expression de la séquence d'acide nucléique codant la protéine d'intérêt dans la plante ou la partie de plante. La plante peut être taillée avant l'introduction d'une ou de plusieurs séquences d'acide nucléique
Patent MA-31827-B1 (MA)
Inventor: LATA PEREZ
IPC: F24S23/77
Filed: 2010-04-07
Abstract: Heliostat facet configured from a flat structure comprising a central section (1) and a peripheral section (2) comprising first (3) and second sides (4), being both sections linked together by a plurality of arms (5, 6), which starting from the central section (1) radially run towards the peripheral section (2) taking as reference the geometrical centre (7) of the facet. In at least three of the arms (5, 6), there are support points (15) of the facet in the corresponding heliostat support (16). The arms (5,6) comprise first arms (5) which are arranged from the central section (1) to the peripheral section (2) running in a divergent manner and at least two couples of second arms (6) which starting from the central section (1) run to the peripheral section (2), the arms (6) of each couple radially running in a convergent manner.
Patent MA-38162-B1 (MA)
Title: Pastille medicamenteuse a base d'ibuprofene sodique dihydrate
Inventor: CORDOLIANI JEAN-FRANÇOIS
IPC: A61K31/192
Filed: 2013-11-14
Abstract: La présente invention a pour objet des pastilles médicamenteuses à sucer, de consistance solide pour se dissoudre dans la cavité buccale comprenant au moins l'ibuprofène sodique dihydraté comme principe actif, destinées au traitement des affections bucco-pharyngées.
Patent MA-51177-B1 (MA)
Title: Processus in situ de production de gaz de synthese a partir de reservoirs d'hydrocarbures souterrains
Inventor: GATES IAN D
IPC: E21B43/243
Filed: 2019-03-06
Abstract: Selon l'invention, un réservoir de pétrole est traité thermiquement pour induire des réactions de gazéification, de conversion de gaz à l'eau et/ou d'hydrothermolyse afin de générer du gaz de synthèse contenant de l'hydrogène. Le gaz de synthèse est produit vers la surface à l'aide d'un ou plusieurs puits de production.
Patent MA-52065-B1 (MA)
Title: Verre feuilleté pour un affichage tête haute pourvu de revêtement électroconducteur et de revêtement antireflet
Inventor: FISCHER KLAUS
IPC: G02B27/01
Filed: 2019-02-04
Abstract: La présente invention concerne un verre feuilleté (10) destiné à un affichage tête haute et pourvu d'un bord supérieur (o), d'un bord inférieur (u) et d'une zone hud (b), comprenant au moins une plaque de verre externe (1) et une plaque de verre interne (2) qui sont reliées par une couche intermédiaire thermoplastique (3), et un revêtement électroconducteur (20) transparent sur la surface (iii), tournée vers la couche intermédiaire (3), de la plaque de verre interne (2) ou à l'intérieur de la couche intermédiaire (3), - la couche intermédiaire (3) étant formée au moins d'une strate (3a) de matière thermoplastique, ladite strate étant interposée entre le revêtement électroconducteur (20) et la plaque de verre externe (1), - l'épaisseur de la strate (3a) de matière thermoplastique dans le sens vertical entre le bord inférieur (u) et le bord supérieur (o) étant variable au moins dans la zone hud (b) d'un angle de coin (a), et - un revêtement antireflet (30) étant appliqué sur la surface (iv), opposée à la couche intermédiaire (3), de la plaque de verre interne (2).