baber/WOPTO huggingface dataset:
Patent CA-2387126-A1 (CA)
Title: Procedes d'identification d'inhibiteurs de methionine aminopeptidases
Inventor: CHANG YIE-HWA
IPC: C12N9/99
Filed: 2000-10-12
Abstract: L'invention concerne des procédés destinés à déceler l'activité de la méthionine aminopeptidase (MAP) et à détecter des inhibiteurs de la MAP. Ces procédés font intervenir un peptide comprenant une méthionine à N-terminaison susceptible d'être coupée du peptide par la MAP et une fraction de détection à C-terminaison libérée par une seconde peptidase à condition que la méthionine à N-terminaison ait été coupée du peptide. Lorsque le peptide est combiné à MAP et à la seconde peptidase, la fraction de détection est libérée. L'addition d'un inhibiteur de MAP a pour but d'inhiber la libération de ladite fraction. Des mélanges réactionnels, des peptides et des kits utilisés pour mettre en oeuvre ces procédés font aussi l'objet de cette invention.
Patent CA-2390329-A1 (CA)
Inventor: SILER STEVEN J
IPC: B41F33/00
Filed: 2002-06-10
Abstract: A printing press may be provided with a first rotatable printing roller that prints ink of a first color on a web of material and causes a first pair of registration marks to be periodically printed in the first color on the web, a second rotatable printing roller that prints ink of a second color on the web of material and causes a second pair of registration marks to be periodically printed in the second color on the web, a third rotatable printing roller that prints ink of a third color on the web of material and causes a third pair of registration marks to be periodically printed in the third color on the web, an imaging device positioned to detect the registration marks printed on the web that generates image data representing the registration marks, and a controller operatively coupled to the printing rollers and the imaging device. The controller may include a processor and a memory, and the controller may be programmed to identify the pairs of registration marks based on the image data and based on registration mark reference data for at least three registration mark pairs defined by a registration mark relationship table.
Patent CA-2392513-A1 (CA)
Title: Forming new sheet flooring widths by controlling application of a bonding agent
Inventor: KRAFT DAVID A
IPC: B29C65/78
Filed: 2002-07-05
Abstract: Methods for creating relatively wide surface coverings and surface covering components by seaming together relatively narrow surface coverings and surface covering components are disclosed. The surface coverings are seamed together with a barely visible or invisible seam by lining up two sheets together and taping them together on one surface at the seam. In one embodiment, the taped surface is the top surface of a surface covering, i.e., the surface that includes the design. The sheets can include thermoplastic polymers. The taped surface is placed downward, and a gluing surface is exposed. The gluing surface is the surface on the two surface coverings to be joined that are in contact with each other. The gluing surface can either be exposed by raising the taped region or by lowering one or both sides adjacent the taped region. A suitable adhesive is applied to the gluing surface and the raised region is lowered or the lowered sides are raised to the original height. Excess adhesive is optionally but advantageously removed, for example, by wiping or skiving the excess off of the non-taped surface, and the adhesive is allowed to set. The method is advantageously used to join together two pieces of thermoplastic sheeting, particularly flooring. If the two pieces are aligned so that they have a pattern similar to the printed pattern of the sheeting, the resulting surface covering appears virtually seamless.
Patent CA-2393257-A1 (CA)
Title: A process for converting storage reserves of dicot seeds into compositions comprising one or more gene products
Inventor: KOIVU KIMMO
IPC: C12N15/82
Filed: 2000-12-08
Abstract: The present invention is related to a process based on a source-sink principle, for producing products of interest from crushed or uncrushed germinating dicot seeds comprising an expression system, which is induced or can be induced during germination. The product is either a seed derived composition comprising one or more gene products. Alternatively, it is a product of interest obtained by placing the composition in contact with a substrate, containing a substance capable of being transformed by the seed derived composition as such, dried or in down-stream processed form.
Patent CA-2393310-A1 (CA)
Inventor: LIU QINGYIAN
IPC: C07D403/12
Filed: 2000-12-11
Abstract: L'invention concerne de nouveaux composés qui sont efficaces dans le cadre de la prophylaxie et du traitement de maladies, telles que des maladies à médiation par récepteurs d'intégrine, notamment des maladies ou des états induits par des récepteurs d'intégrine, tels que .alpha.¿v?.beta.¿3?, .alpha.¿v?.beta.¿5?, .alpha.¿v?.beta.¿6?, .alpha.¿5?.beta.¿1? et similaire. Cette invention concerne des composés nouveaux, des sels correspondants acceptables pharmaceutiquement, des compositions pharmaceutiques et des méthodes destinées à la prophylaxie et au traitement de tels maladies et troubles. Ladite invention a également trait à des procédés d'élaboration de tels composés ainsi qu'à des intermédiaires utilisés dans de tels procédés.
Patent CA-2393898-A1 (CA)
Title: Methods and devices for creating collateral channels in the lungs
Inventor: DAVENPORT JAMES M
IPC: A61B17/064
Filed: 2000-08-07
Abstract: Published without an Abstract
Patent CA-2394252-A1 (CA)
Title: A lid for a refuse container
Inventor: ERNST TIBOR
IPC: B65F1/02
Filed: 2000-12-21
Abstract: A lid (14) for fitting to an open-topped refuse container (10) has a compacting mechanism comprising a compacting plate (36) mounted under the lid, a telescopically adjustable actuating rod (42) mounted over the lid, and means (40) slidably coupling the plate to the rod through an aperture in the lid such that the rod may be manoeuvered from a storage position wherein the rod lies across the lid and the plate is drawn up under the lid to an operative position wherein the rod stands upright over the aperture and may be pushed downwardly through the aperture (as seen in the figure) to push the plate down into the container.
Patent CA-2395698-A1 (CA)
Title: Reconstructing organs from decellularized biomaterial scaffold
Inventor: ATALA ANTHONY
IPC: A61K35/12
Filed: 2000-12-14
Abstract: The invention is directed to compositions and methods for reconstructing an artificial organ. The artificial organ is reconstructed using a three-dimensional scaffold produced by decellularizing biostructures from a donor organ. The three-dimen-sional scaffold is perfused with endothelial cells that develop to produce an endothelial tissue layer with a primitive vascular system that sustains the growth and development of a second cultured cell population.  When grown in the three-dimensional scaffold and endothelial tissue layer, with the primitive vascular system, the cells of the second cell population proliferate, mature and differentiate into neomorphic organ structures that are analogous to their in vivo counterparts.
Patent CA-2402100-A1 (CA)
Title: Product packaging with display
Inventor: CHASSE CARL A
IPC: B65D51/28
Filed: 2002-09-10
Abstract: A package for a plurality of products, having a closed container having a container wall, the wall defining a cavity for holding the products, and the wall having a product holder adapted to hold at least one selected product in a position visible from outside the container. The holder is an inwardly and/or outwardly opening recess formed in the wall, and the at least one selected product is positioned in the recess. The holder includes an outer member restraining die selected product to the outwardly opening recess, such as a packaging label, having a transparent portion forming a viewing window for viewing the selected product. In yet another aspect, the plurality of products in the cavity may be identical primary products, such as screws. The selected product may be different from the primary product, such as a driver bit for driving the screws.
Patent CA-2403537-A1 (CA)
Inventor: BAIRD ELDON E
IPC: A61K31/7052
Filed: 2001-03-14
Abstract: L'invention concerne des composés chargés comprenant une ou plusieurs zones de charge positive localisés, des compositions contenant lesdits composés, des procédés pour synthétiser lesdits composés, des procédés de criblage de tels composés afin d'identifier ceux qui présentent une activité anti-infectieuse, ainsi que des procédés d'utilisation desdits composés afin de prévenir ou d'inhiber des infections. Ces composés et les compositions les contenant présentent des applications multiples et peuvent même s'utiliser en médecine humaine et animale et dans l'agriculture.
Patent CA-2405438-A1 (CA)
Title: Hepatitis b core antigen fusion proteins
Inventor: GILBERT ROBERT
IPC: C12N1/19
Filed: 2001-04-09
Abstract: The hepatitis B virus (HBV) capsid is made up of a single species of protein  called the core antigen (HBcAg) which self-assembles into particles. The particles are highly immunogenic and are able to present heterologous epitop es to the immune system when the epitopes are inserted into a surface-exposed region of the particles called the "el loop". The structural building blocks  of the particles are tightly associated dimers of HBcAg in which the adjacen t el loops are closely juxtaposed. It is proposed that sequences inserted into  the el loop are conformationally restrained in the assembled particles when presented in monomeric core protein. The invention seeks to solve this probl em by covalently linking core proteins as tandem copies, e.g., as dimers, so th at insertions can be made independently in each copy. This is particularly usef ul for insertion of large sequences into the el loop because it allows such sequences to be inserted into just one copy of the core protein per tandem repeat, thereby reducing potential conformational clashes in assembly. Alternatively, a different sequence may be inserted into each el loop of a tandem repeat, thus increasing the flexibility of HBcAg particles as an epitope delivery system.
Patent CA-2405700-A1 (CA)
Inventor: TSUI ALEX KOWK KEE
IPC: G06Q30/04
Filed: 2002-09-30
Abstract: A web service interface defined for a billing service, comprising a plurality of application programming interfaces, where each application programming interface is associated with a billing function provided by the billing service, where each of the application programming interfaces can be implemented such that the billing function associated therewith is performed after a web service invocation that commands performance of that billing function is received by the web service interface. The web service interface is used to provide the billing service as a web service to computing applications in a distributed network environment.
Patent CA-2411202-A1 (CA)
Title: Dispositif d'administration de medicament
Inventor: DAILY DAVID
IPC: A61M5/145
Filed: 2001-05-23
Abstract: L'invention concerne un dispositif d'administration de médicament pourvu d'un logement comprenant un réservoir interne en communication, par l'intermédiaire d'un canal de passage de fluide, avec un orifice de sortie permettant l'administration d'un médicament. Une chambre à volume variable placée à côté du réservoir entraîne le médicament provenant du réservoir vers l'orifice de sortie lorsque ladite chambre est alimentée en gaz. Une chambre de régulation du débit, en communication avec le canal de passage de fluide, est conçu pour changer de volume sous l'effet de changements de température et/ou de pression. Une augmentation de volume de la chambre de régulation du débit augmente la résistance du débit à l'orifice de sortie et, ainsi, permet de compenser l'augmentation correspondante du débit d'administration résultant de l'expansion de la chambre à volume variable provoquée par les mêmes changements volumétriques sous l'effet de la température et/ou de la pression. Dans un mode de réalisation privilégié, un circuit électrique est pourvu d'un élément de stabilisation du courant qui est relié électriquement à une cellule électrolytique assurant l'alimentation en gaz. Un dispositif d'étranglement maintient une pression élevée dans le dispositif de manière à réduire l'engorgement éventuel du canal de passage de fluide. Dans un mode de réalisation privilégié le dispositif d'administration de médicament est présenté sous emballage de manière à être isolé de la pression atmosphérique et de l'humidité.
Patent CA-2413556-A1 (CA)
Title: Analogues d'acides nucleiques peptidiques charges positivement a proprietes ameliorees
Inventor: GIBSON DAN
IPC: C07D473/18
Filed: 2001-06-22
Abstract: La présente invention concerne de nouveaux types d'acides nucléiques peptidiques (PNA) dotés de propriétés améliorées. L'invention concerne, en particulier, des unités PNA chargées positivement comportant une liaison éthylène entre le squelette et la nucléobase, des analogues oligonucléotidiques comprenant lesdites unités, des oligomères comprenant lesdites unités, ainsi que l'utilisation de ces PNA chargés positivement comme nouveaux agents d'administration dans le cadre d'applications thérapeutiques et diagnostiques, notamment la thérapie antisens.
Patent CA-2413822-A1 (CA)
Inventor: DAHL PAMELA S
IPC: A61K51/12
Filed: 2001-07-16
Abstract: A brachytherapy seed comprising (a) carrier-free 103Pd isotope, (b) a substrate for the carrier-free 103Pd radioisotope, and (c) a casing for encapsulating the carrier-free 103Pd-laden substrate, is disclosed.
Patent CA-2414094-A1 (CA)
Inventor: TAYLOR LARRY
IPC: A61P3/00
Filed: 2000-05-25
Abstract: La présente invention concerne des procédés d'extraction et de purification de substances bioactives à partir de plantes et d'herbes variées. Plus spécifiquement, cette invention concerne des procédés d'extraction et de séparation de substances bioactives à partir de plantes et d'herbes variées, telles que les racines de Kava, l'espèce Byrsonima, Aesculus californica, Crataegus mexicana, Simmondsia chinensis, l'espèce Pfaffia, Alternanthera repens, l'espèce Bursera, l'espèce Turnera, l'espèce Perezia, Heimia salicifolia, l'espèce Psidium, l'espèce Enterlobium, Ptychopetalum olacoides, Liriosma ovata, et Chaunochiton kappleri, en utilisant l'extraction avec fluide supercritique et/ou un extrait de solvant fluorocarboné. En outre, cette invention concerne la séparation de substances bioactives contenues dans les extraits en utilisant la chromatographie à fluide supercritique sur colonne garnie, ou HPLC, où le gaz dense avec ou sans modificateurs représente la phase mobile. En outre, cette invention concerne des préparations pharmaceutiques et des suppléments alimentaires pouvant être préparés avec ces substances bioactives extraites, et concerne enfin l'utilisation de ces préparations pharmaceutiques et suppléments alimentaires pour traiter des aliments humains variés.
Patent CA-2417314-A1 (CA)
Inventor: WAHL DAVID
IPC: B62D55/125
Filed: 2003-01-27
Abstract: Pignon d'entraînement pour une motoneige, train d'entraînement utilisant le pignon, et méthode d'utilisation du pignon pour entraîner une chenille de motoneige. Le pignon d'entraînement comprend une base ronde, une pluralité de barrettes convolutées sur la base, et une pluralité de barrettes développantes sur les deux côtés de la base. La base est de préférence en forme de disque, et les barrettes convolutées sont de préférence alignées avec les barrettes développantes. Dans le mode de réalisation préféré, un nombre de barrettes convolutées représente la moitié des barrettes développantes. Les barrettes convolutées doivent s'aligner avec des fenêtres dans une chenille pour la motoneige, et les barrettes développantes doivent s'aligner avec des espaces entre des bosses sur la chenille de la motoneige. De préférence, le pignon comprend également un moyeu avec un trou traversant pour un arbre d'entraînement et des bras raidissant s'étendant du moyeu. Les bras raidissant peuvent inclure des supports pour les barrettes développantes. Un raidissement plus grand peut être obtenu avec des bords relevés de chaque côté de la base. De la même façon, les barrettes convolutées peuvent comprendre des replis de raidissement.
Patent CA-2418057-A1 (CA)
Inventor: BECKMANN FRIEDHELM
IPC: B29C48/03
Filed: 2001-07-28
Abstract: The invention relates to a method for the production f a reinforced plastic component, in particular, by injection moulding, extruding or extrusion blowing, whereby a thermoplastic base material is prepared as a melt and a reinforcing material obtained from plant material is introduced. Said reinforcing material is in the form of comminuted shavings which may be poured and dispensed, in particular, derived from annual plants and/or similarly comminuted woody components from china red.  The above material is added to the melt of the base material and mixed to give a homogeneous material, whereby the reinforcing material essentially contains no fractions of fibrous material which effect the ability thereof to be poured or dispensed.
Patent CA-2418574-A1 (CA)
Title: Downhole fluid disposal apparatus and methods
Inventor: MICHAEL CLARENCE
IPC: E21B43/38
Filed: 2003-02-05
Abstract: A seal cartridge and barrel manifold seal are provided for use in a subterranean well and in a method to inject fluid, that is initially produced into the well from a subterranean formation or zone, into another subterranean formation or zone. The seal cartridge has two distinct annular seals positioned within opposite sides of a unitary housing to inhibit fluid flow through the housing in both axial directions along a rod that is positioned through the housing. A barrel seal manifold is provided that is unitary in design and has tapered flow surfaces thereby provided increased strength, flow dynamics and life.
Patent CA-2422709-A1 (CA)
Title: Substituted cinnamic acid guanidides, method for the production thereof,their use as a medicament, and to a medicament containing these compounds
Inventor: HROPOT MAX
IPC: A61P9/10
Filed: 2001-09-08
Abstract: The invention relates to cinnamic acid guanidides, to a method for the production thereof, to their use as a medicament or diagnostic reagent, and to a medicament containing these compounds. According to the invention, compounds of formula (I), in which R(1), R(2), R(3), R(4), R(5), R(6), and R(7) have the meanings cited in the claims, are excellent cardiovascular therapeutic agents.  These are obtained by reacting a compound of formula (II) with guanidine.
Patent CA-2428524-A1 (CA)
Title: Peak reduction for simulcast broadcast signals
Inventor: WILDHAGEN JENS
IPC: H04B1/04
Filed: 2003-05-12
Abstract: A reduced peak simulcast signal generator and a method for generating a stable peak-attenuated simulcast signal, which combines a digital broadcast signal and an analogue broadcast signal, are described. The simulcast signal generator comprises at least one attenuation stage for attenuating the digital and/or the analogue broadcast signal in  order to obtain a stable simulcast signal. Each attenuation stage comprises a simulcast signal generator for generating an error signal, and attenuation means which attenuate, in dependence of said first error signal, at least one of the analogue and the digital broadcast signal.
Patent CA-2436429-A1 (CA)
Title: Use of dinucleoside polyphosphate to stimulate removal of fluid in retinal disorders
Inventor: YERXA BENJAMIN R
IPC: A61K47/36
Filed: 2002-01-29
Abstract: The present invention provides a method of treating edematous retinal disorders. The method comprised administration of a pharmaceutical compositi on comprising a P2Y receptor agonist to stimulate the removal of pathological extraneous fluid from the subretinal and retinal spaces and thereby reduce t he accumulation of said fluid associated with retinal detachment and retinal edema. The P2Y receptor agonist may be administered with therapeutic and adjuvant agents commonly used to treat edematous retinal disorders. The pharmaceutical compostion useful in this invention comprises a P2Y receptor agonist with enhanced resistance to extracellular hydrolysis, such as dinucleoside polyphosphate compounds.
Patent CA-2438370-A1 (CA)
Title: Command synchronization establishment system
Inventor: ABE TATSUTOSHI
IPC: H04L12/28
Filed: 2003-08-28
Abstract: A command synchronization establishment system using a network wherein data is transferred by an isochronous transfer, a command is transferred by an asynchronous transfer, and a synchronized clock is shared by apparatuses connected to the network, the system comprising a controller connected to the network, comprising a transmitter that transmits a command including a time- stamp to a target apparatus by using the asynchronous transfer, and the target apparatus connected to the network, comprising a receiver that receives the command, a storage device that temporarily stores the received command in order not to execute the received command instantly, and a executing device that executes the received command in accordance with the time-stamp included in the command to be executed.
Patent CA-2439767-A1 (CA)
Inventor: FERRAIOLO FRANCESCO
IPC: E01F8/02
Filed: 2003-09-05
Abstract: A barrier for protection against shock waves comprises, in combination with each other, a plurality of soil containing and reinforcing structures (20, 22) superimposed on each other in such a way as to form two vertical walls (12).        Means of absorbing shock waves (30) are positioned inside the said walls (12). The protective barrier also comprises transverse connecting means (14, 50, 80) engaged with the vertical walls (12) to enhance the compactness of the protective barrier.
Patent CA-2441547-A1 (CA)
Inventor: SPEAR KEVIN W
IPC: G06Q20/34
Filed: 2002-03-20
Abstract: A hybrid credit card transaction system that processes transactions as either virtual standard transactions directed through a clearing house or as virtual closed loop transactions bypassing the clearinghouse, is disclosed. The system includes a logic enabled merchant that directs virtual closed loop transactions and directs them to an affiliated acquiring entity which acquires the virtual closed loop transactions and routes them directly to an affiliated card issuing entity so as to bypass the clearinghouse. The affiliated card issuing entity debits virtual standard transactions to a credit card account and virtual closed loop transactions to a private label account. The logic enabled merchant, associated acquiring entity and the associated card entity may be affiliated by participation in an Internet site that promotes transactions between small businesses and merchants selling wholesale goods. A  reduction in processing fees accrued when bypassing the clearinghouse promotes issuance and use of the hybrid credit cards.
Patent CA-2444989-A1 (CA)
Inventor: MCCORMACK SUSAN
IPC: A47B83/02
Filed: 2003-10-15
Abstract: A "U" shaped steel foot is axially mounted on the wheel axle mounted on a picnic table leg for the purpose of ease of relocation by wheeling to another site. The steel foot freely pivots from a stored position to make contact with the ground. A push from the opposite side of the table induces the foot to rotate which action causes the wheel to be lifted free of the ground. A pull on the table from said opposite side will induce the foot to rotate and allow the wheel to make contact with the ground where said foot is placed by hand in the stored position and secured by a turn button or any spring loaded holding device.