baber/WOPTO huggingface dataset:
Patent CA-2689064-A1 (CA)
Inventor: BORRAS LEONARDO
IPC: G16B15/30
Filed: 2008-06-25
Abstract: The invention provides methods of using sequence based analysis and rational strategies to modify and improve the structural and biophysical properties of single chain antibodies (scFvs), including stability, solubility, and antigen binding affinity. These methods and strategies can be used individually or in combination. The methods of the present invention also include the use of a database comprising scFv sequences from an experimentally screened scFv library of antibodies that have been selected to have superior solubility and stability. The invention also provides methods of using the properties found for these selected antibodies in a general approach for reshaping scFv antibodies to improve stability and solubility properties of a single chain antibody fragment.
Patent CA-2690424-A1 (CA)
Inventor: GALLORO VITO
IPC: A47B61/00
Filed: 2010-01-18
Abstract: A kit of parts for a closet storage system includes a plurality of poles, and a plurality of fitments. Each fitment has a first end, an opposed second end, and a fitting section pre-connected to each of the ends. The kit of parts further includes a plurality of fitting sections not pre-connected to any of the fitments, and a plurality of nuts.  Each of the fitting sections has a body defining a generally half cylindrical surface, a first longitudinally split bolt protruding from one side of the body and a second longitudinally split bolt protruding from a second side of the body. Any two of the fitting sections may be placed with their split bolts adjacent each other forming complete bolts and a pole within their half cylindrical surfaces. The nuts are sized to thread onto the complete bolts.
Patent CA-2691627-A1 (CA)
Inventor: INOUE YASUO
IPC: G09G3/20
Filed: 2008-07-08
Abstract: Provided is a display device including a display unit having luminescence elements that individually becomes luminous depending on a current amount. The luminescence elements are arranged in a matrix pattern. The display device comprises a luminescence amount regulator for setting a reference duty for regulating a luminescence amount per unit time for each of the luminescence elements, according to picture information of an input picture signal, and also comprises an adjuster for adjusting, based on the reference duty, an effective duty regulating a luminous time for which the luminescence elements become luminous within a unit time, so that the effective duty is within a predetermined range, and for adjusting a gain of the picture signal, so that a luminescence amount regulated with the effective duty and with the gain of the picture signal equals to the luminescence amount regulated with the reference duty.
Patent CA-2692432-A1 (CA)
Inventor: OAKLEY DOUG
IPC: E21B43/08
Filed: 2008-05-07
Abstract: A method for drilling and completing a wellbore that includes drilling a wellbore through a subterranean formation with a wellbore fluid, the wellbore fluid comprising: a base fluid; and micronized weighting agent; and disposing a sand screen in an interval of the wellbore with the wellbore fluid is disclosed.
Patent CA-2694300-A1 (CA)
Inventor: CRIDER GRANT W
IPC: E06B9/08
Filed: 2008-07-16
Abstract: A combination garage door and roll-up curtain system that allows a flexible curtain (42) to be lowered when the garage door (21) is in a raised position. The system preferably comprises an automated garage door assembly wherein the drive mechanism is mounted to a bracket (31) mounted in turn to the inside wall (16) above the garage opening (10) upper margin. The system preferably further comprises an automated roll-up curtain assembly having a rotatable rod (41) mounted above the garage opening upper margin between the bracket and the inside wall. The rotatable rod has a flexible curtain (42) wound thereabout wherein the first end of the curtain is affixed to the rod and the second end of the curtain is secured along its lateral margins (42a) within tracks (45) mounted adjacent the garage opening lateral margins (11 a, 11 b).
Patent CA-2694884-A1 (CA)
Title: Connecteur avec contact perce-isolant
Inventor: MILETTE LUC
IPC: H01R24/58
Filed: 2008-08-01
Abstract: L'invention concerne un connecteur et un procédé pour terminer un câble comprenant des paires de conducteurs torsadées. Un inconvénient majeur de l'art antérieur est que, comme le point d'insertion de conducteurs individuels dans les connecteurs est agencé le long d'une ligne parallèle, des interférences indésirables et similaires peuvent apparaître, ce qui réduit la qualité du connecteur, en particulier aux fréquences élevées. En outre, la séparation entre les conducteurs d'une paire torsadée n'est pas maintenue de façon rigoureuse. Dans un aspect de l'invention, le connecteur (10) comprend un guide passe-fil (16) pour agencer les paires de conducteurs torsadées (70) et une pluralité de contacts perce-isolant (40) qui s'interconnectent avec des conducteurs respectifs des paires de conducteurs torsadées lorsque le guide-fil est fixé au module. Dans un autre aspect de l'invention, le guide passe-fil est fixé au module. Dans un autre aspect de l'invention, le guide passe-fil (16) garantit que l'espacement entre les conducteurs d'une paire torsadée particulière (70) est maintenu, ce qui améliore la qualité de l'assemblage subséquent.
Patent CA-2697680-A1 (CA)
Inventor: CAVALI PAULO TADEU MAIA
IPC: A61F2/44
Filed: 2007-12-07
Abstract: Flexible, sliding, dynamic implant system, for selective stabilization and correction of the vertebral column deformities and instabilities is constituted of a set is constituted by a set of flexible vertebral implants, which are articulated, sliding and dynamic (1) that belongs to the prosthetic and implants medicine field, constituted of two linear parallel sequences of U-shaped supports or -platforms (3) where each pair of the sequence is connected with selective mobility to pedicular screws (4) fixed, also in pairity, in the due posterior bony portion (5) of each vertebra (6) two thin, continue and flexible metallic blades (8) are coupled between the edges (lateral portion of the platforms with tracks (7) which belong to each U-shaped support. The inferior thin blade (8) is a fixed to the first U-shaped support (3) which corresponds to the first inferior vertebra (6) of the vertebral portion to be implanted.  The flexible thin blade (8) is, on its turn, fixed on the upper vertebra platform in a way that it is blocked in only one extremity, thus with the free internal extremity causing the blades to slide in postural flex condition or any other movement requested to the extension of the implanted vertebral column (2).
Patent CA-2699612-A1 (CA)
Inventor: FISH ROBERT D
IPC: G01N21/64
Filed: 2008-03-31
Abstract: A molecular construct comprises a donor label, an acceptor label, a linker peptide disposed between the donor and the acceptor, the linker having a cleavage site sequence, and a spacer between at least one of (a) the donor and the cleavage site sequence and (b) the acceptor and the cleavage site sequence. Preferably, the construct is selected from the group consisting of CFP-(SGLRSRA)-SNAP-25-(SNS)-YFP, and CFP-(SGLRSRA)-synap-tobrevin-(SNS)-YFP. In preferred embodiments, the linker peptide is a substrate of a botulinum neurotoxin selected from the group consisting of synaptobrevin (VAMP), syntaxin and SNAP-25, or a fragment thereof that can be recognized and cleaved by the botulinum neurotoxin.  Advantageously, the spacer increases the electronic coupling between the donor label and the acceptor label relative to a corresponding construct without the spacer.
Patent CA-2701748-A1 (CA)
Title: Sealing segment and sealing-segment arrangement
Inventor: ASCHENBRUCK EMIL
IPC: F01D11/00
Filed: 2008-11-03
Abstract: A sealing segment is disclosed for sealingly connecting two structural components parts which are movable relative to one another, with two sealing bodies which are connected to one another by a web and which can be arranged in recesses of the structural component parts in an articulated manner, and a sealing segment arrangement with a plurality of sealing segments of this type, and a flow machine with a sealing segment arrangement of this type.
Patent CA-2702943-A1 (CA)
Title: Tunnel washer system with improved cleaning efficiency
Inventor: CANTIN EUGENE
IPC: B08B3/04
Filed: 2006-09-08
Abstract: A tunnel washer that includes fluid exhaust paths that are optimized to minimize fluid transfer between chambers of the washer and minimize heat loss from each chamber of the washer. The fluid exhaust paths also facilitate uniform vapor evacuation from each chamber of the washer. The tunnel washer also includes spaced-apart double wall curtains for isolating chambers of the tunnel washer to prevent fluid and heat transfer therebetween, and to the exterior of the tunnel washer. The double wall curtains include surfaces that inhibit the curtains from sticking together during operation of the tunnel washer. The tunnel washer also includes an air manifold that provides uniform drying efficiency for articles of varying dimensions.
Patent CA-2704194-A1 (CA)
Title: An orally-absorbed solid dose formulation for vancomycin
Inventor: SHANKAR GITA NATARAJAN
IPC: A61K9/48
Filed: 2007-10-30
Abstract: An orally bioavailable pharmaceutical composition comprises at least 40% (w/w) vancomycin; a permeation en-hancer component comprising 0.1 to 10.0% (w/w) of a polyoxyethylene sorbitan fatty acid ester; and a particulate carrier onto which the permeation enhancer component is adsorbed.
Patent CA-2710218-A1 (CA)
Title: Process for the purification of fluoromethyl 1,1,1,3,3,3,-hexafluoroisopropyl ether (sevoflurane)
Inventor: JONES BARRY
IPC: C07C41/38
Filed: 2008-12-22
Abstract: A process for purifying crude fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane). The crude sevoflu-rane is repeatedly washed with water under conditions and for a time sufficient to reduce the level of 1,1, 1,3,3, 3-hexafluoroiso-propanol (IIFIP) to no more than 200 ppm or no more than 100 ppm.
Patent CA-2713660-A1 (CA)
Inventor: PERKINS TIMOTHY D
IPC: A01G23/14
Filed: 2010-08-18
Abstract: A line system for a maple syrup production system, where the lateral lines have an inside diameter greater than 5/16" nominal and less than or equal to 3/4" and the lateral line fitting and mainline fitting have a nominal inside diameter of greater than 0.225" and less than or equal to 0.70". Further, the line system has drop lines with an inside diameter greater than 5/16" nominal and less than or equal to 3/4" and the spout fitting has a nominal inside diameter of greater than 0.225" and less than or equal to 0.70". The increased inside diameters of the drop lines, lateral lines, spout fittings, lateral line fittings and mainline fittings dramatically improves the flow of air and sap from the taphole and through the line system.
Patent CA-2715234-A1 (CA)
Inventor: GILBERT JAMES A
IPC: A61B18/12
Filed: 2010-09-23
Abstract: An automatic control circuit for an electrosurgical generator is herein disclosed. The automatic control circuit includes voltage and current sensing circuits, a processing circuit, a dosage calculating circuit, and control circuit. Samples of the voltage and current outputs are supplied to the processing circuit and the dosage calculating circuit to generate a dosage output signal. The dosage output signal is compared to a reference signal to generate a feedback signal that controls a drive circuit.
Patent CA-2715502-A1 (CA)
Inventor: ARUMAITHURAI MAYUTAN
IPC: H04L29/08
Filed: 2009-03-17
Abstract: A computer network is provided. The computer network comprises an AAA  (Authentication, Authorization, and Accounting) client with an extension for requesting location information of a user.
Patent CA-2715753-A1 (CA)
Title: Refractory slag band
Inventor: ROGERS NORMAN EDWARD
IPC: C04B35/106
Filed: 2009-02-12
Abstract: The present invention resides in a refractory composition for use as a cold start slag band. The composition com-prises an admixture of partially stabilised zirconia and/or fully stabilised zirconia and monoclinic zirconia, characterised in that the proportion of monoclinic relative to the total zirconia content is at least 40% by weight. The invention also resides in a slag band formed from the composition, a submerged entry nozzle incorporating the slag band and a method of forming such a sub-merged entry nozzle.
Patent CA-2719639-A1 (CA)
Title: Thermally enhanced electrically insulative adhesive paste
Inventor: CZUBAROW PAWEL
IPC: C09J9/00
Filed: 2009-03-26
Abstract: A thermal interface material comprises larger conformable thermally conductive particles, and smaller ceramic thermally conductive particles in a binder. The binder can include thermoplastic (and optionally thermoset) particles and a fugitive liquid which are substantially insoluble in each other. The binder can also include a liquid epoxy. Each of the larger thermally conductive particles is itself a cohesive yet conformable agglomeration of platy particles.
Patent CA-2720617-A1 (CA)
Inventor: NAYLOR DEAN JASON
IPC: A61P37/02
Filed: 2009-04-09
Abstract: The present invention relates to isolated Cpn10 polypeptides possessing an increased affinity for a PRR ligand compared to Ala Cpn10 polypeptide. In a further embodiment, the present invention also relates to modified chaperonin 10 polypeptides, and to nucleic acids encoding the same and to compositions comprising such polypeptides and uses thereof.
Patent CA-2723122-A1 (CA)
Inventor: SEPPAE HEIKKI
IPC: G06V30/224
Filed: 2009-05-14
Abstract: The present publication discloses a method and device for reading an electronic code. According to the method, an alternating electrical signal is brought to the code (11) being measured, with the aid of electrodes (4, 5), and the current or voltage travelling through the electrodes (4, 5) is measured. According to the invention, the real (8) and the imaginary (9) components of the current or correspondingly the voltage are defined, and the electrodes (4, 5) being on an essentially lossless surface, an angle correction is made to the real (8) and imaginary (9) components of the current or the voltage, in such a way that substantial changes in the current take place only in the imaginary component (9) of the current or voltage.
Patent CA-2723728-A1 (CA)
Inventor: QING SHAN
IPC: H04L29/06
Filed: 2009-05-19
Abstract: Certain embodiments allow security keys to be maintained across mobile device states, or communication events, such as hand-over, and system idle and sleep power savings modes. By monitoring the lifetime of security keys, keys may be refreshed in an effort to ensure key lifetimes will not expire during a hand-over process or other device unavailable state.
Patent CA-2725760-A1 (CA)
Inventor: PEROU CHARLES M
IPC: C12Q1/6809
Filed: 2009-06-01
Abstract: Methods for classifying and for evaluating the prognosis of a subject having breast cancer are provided. The methods include prediction of breast cancer subtype using a supervised algorithm trained to stratify subjects on the basis of breast cancer intrinsic subtype. The prediction model is based on the gene expression profile of the intrinsic genes listed in Table 1. This prediction model can be used to accurately predict the intrinsic subtype of a subject diagnosed with or suspected of having breast cancer. Further provided are compositions and methods for predicting outcome or response to therapy of a subject diagnosed with or suspected of having breast cancer. These methods are useful for guiding or determining treatment options for a subject afflicted with breast cancer. Methods of the invention further include means for evaluating gene expression profiles, including microarrays and quantitative polymerase chain reaction assays, as well as kits comprising reagents for practicing the methods of the invention.
Patent CA-2725846-A1 (CA)
Inventor: WANG CHAO CHUN
IPC: H04B7/005
Filed: 2009-06-17
Abstract: A communications system including communications devices is provided. A communications device, a trainer, generates at least one concatenated training sequence, transmits the at least one concatenated training sequence, and receives one or more response messages describing corresponding channel characteristics from at least one of the rest of the plurality of communications devices. One or more of the rest of the plurality of communications devices, trainees, each receives the at least one concatenated training sequence, determines channel characteristics between the trainer and a trainee according to the at least one received concatenated training sequence, embeds channel characteristics information to generate at least one of the response messages, and transmits the response message.
Patent CA-2725946-A1 (CA)
Title: Method of musical instrument manufacturing incorporating tissue engineering techniques
Inventor: GILLIS ARCHIE
IPC: G10D13/24
Filed: 2010-12-21
Abstract: .cndot. The present invention provides a method of fabricating musical instruments or portions thereof using tissue-engineering technologies. .cndot. Biofabrication is a collection of tissue engineering technologies that can be defined as the production of complex living and non-living biological products from raw materials such as living cells, molecules, extracellular matrices, and biomaterials. In the preferred embodiment of the present invention it will be these methods that are used to create musical instruments or portions thereof. .cndot. One of the novel features of the present invention is the incorporation of plant cells in the tissue engineering/biofabrication environment.
Patent CA-2733447-A1 (CA)
Inventor: AVITABILE BARBARA GUISEPPINA
IPC: A61P11/08
Filed: 2009-08-11
Abstract: The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is a selected muscarinic receptor antagonist, and a second active ingredient which is selected from a phosphodiesterase inhibitor, a modulator of chemokine receptor function, an inhibitor of kinase function, a protease inhibitor, a steroidal glucocorticoid receptor agonist, a non-steroidal glucocorticoid receptor agonist and a purinoceptor antagonist, of use in the treatment of respiratory diseases such as chronic obstructive pulmonary disease and asthma.
Patent CA-2737307-A1 (CA)
Inventor: LINDELL KATARINA
IPC: A61K9/24
Filed: 2009-10-13
Abstract: The present invention relates to a multi portion intra-oral dosage form where at least one portion is rapidly disintegrating and at least one portion is slowly disintegrating, whereby the disintegration time for the slowest disintegrating portion is at least two times longer than for the most rapidly disintegrating portion. Of certain interest is use of sensory markers/signals as conceptual aids for the subject.,Also contemplated are a method and a system for delivering active agents, such as,nicotine and/or metabolites thereof, such as cotinine, nicotine N'-oxide, nornicotine, (S)-nicotine-N-.beta.-glucuronide and mixtures, isomers, salts and complexes thereof as well as use and production of said formulations.
Patent CA-2737535-A1 (CA)
Title: Procede de diagnostic d'une sclerodermie systemique ou d'une hypertension arterielle pulmonaire
Inventor: MOUTHON LUC
IPC: G01N33/564
Filed: 2009-09-17
Abstract: L'invention concerne un procédé in vitro de détection d'une sclérodermie systémique (ScS) et/ou d'une hypertension artérielle pulmonaire (HTAP), ou d'un risque de développer une ScS ou une HTAP, comprenant la détermination de la présence et/ou de la quantité d'anticorps dans un échantillon biologique provenant d'un patient.
Patent CA-2737780-A1 (CA)
Inventor: CINK JAMES H
IPC: A01M23/08
Filed: 2009-09-21
Abstract: A live trap (100) is provided for trapping rodents.    The live trap includes a housing having an interior space and at least one opening (106) through which rodents enter the interior space of the housing. A first trap mechanism (108) is provided that is positionable in the live trap for trapping rodents within the live trap. A second trap mechanism is provided that is different from the first trap mechanism and positionable in the live trap for trapping rodents within the live trap. The live trap and trap mechanisms are configured for selective releasable securement of each of the respective first and second trap mechanisms in the live trap to permit interchangeable use of the first and second trap mechanisms in the live trap.
Patent CA-2739525-A1 (CA)
Inventor: MALFAIT TONY
IPC: B32B7/06
Filed: 2009-08-25
Abstract: The present invention relates to a coextruded multilayer polyolefin film, said polyolefin film being substantially curl-free in use, said polyolefin film comprising : a polyolefinic base layer comprising between 10 % and 50 % by weight of a cyclic olefin copolymer having a Tg higher than 1300C; a polyolefinic sealing layer having a thickness between 5 and 15 % of the total film thickness.
Patent CA-2739607-A1 (CA)
Inventor: CHADWICK DONALD T
IPC: A47C7/62
Filed: 2005-07-08
Abstract: A chair having a seat rotatably attached to a tilt spring portion of a tilt mechanism such that the tilt spring is activated by movement of the seat. A  backrest and/or the seat can be rotatably connected to the tilt mechanism by parallel arm arrangements which permit the seat and backrest to tilt relative to each other. A tilt limiter can have a magnetic member which facilitates full movement of the tilt limiter between free and locked positions, and which creates an audible indication of full movement of the tilt limiter. The seat/backrest can be made from a flexible mesh material secured to a rigid overmolding which surrounds and is attached to an inner frame of the seat/backrest wherein an outer surface of the overmolding forms an outer surface of the seat/backrest frame and attachment of the overmolding causes the inner frame to stretch the mesh to a final condition.
Patent CA-2740550-A1 (CA)
Title: Silanes blend
Inventor: ZASTRAU RALF
IPC: C09D4/00
Filed: 2009-10-07
Abstract: The present invention relates to a composition comprising at least two fluorosilanes and at least one aminosilane, a condensation product of said fluorosilanes and said aminosilane, and a surface protective agent made thereof.
Patent CA-2742509-A1 (CA)
Inventor: KULIOPULOS ATHAN
IPC: A61K38/08
Filed: 2009-11-04
Abstract: The invention relates generally to compounds which are allosteric modulators (e.g., positive and negative allosteric modulators, and allosteric agonists) of the G protein coupled receptor for stromal derived factor 1(SDF-I), also known as the CX-CR4 receptor. The CXCR4 receptor compounds are derived from the intracellular loops and domains of the CXCR4 receptor. The invention also relates to the use of these CXCR4 receptor compounds and pharmaceutical compositions comprising the CXCR4 receptor compounds in the treatment of diseases and conditions associated with CXCR4 modulation such as bone marrow transplantation, chemosensitization, cancer, metastatic disease, inflammatory diseases, HIV infection and stem cell-based regenerative medicine.
Patent CA-2744100-A1 (CA)
Inventor: AUSTEN WILLIAM G JR
IPC: A61K35/35
Filed: 2009-10-21
Abstract: The present invention provides polymers for use in preventing damage to the membranes of cells in fat grafts. Mixing of a triblock copolymer such as poloxymer P 188 with adipocytes or adipose tissue to be transplanted into a subject is thought to stabilize the membranes of the cells leading to more successful fat transplantation in soft tissue reconstruction or augmentation. Such methods may also be used in the transplantation of adult stem cells or other cells derived from fat tissue. Other agents such as lipoic acid may also be added to the polymer/cell compositions for cell transplantation.