baber/WOPTO huggingface dataset:
Patent EP-4130043-A1 (EP)
Title: Anti-human cd47 antibody and antigen-binding fragment thereof, and preparation method therefor and use thereof
Inventor: GU LIYUN
IPC: C07K16/28
Filed: 2021-03-31
Abstract: Provided in the present invention are an anti-human CD47 antibody or an antigen-binding fragment thereof, and a preparation method therefor and the use thereof. Also provided in the present invention are an isolated polynucleotide encoding the antibody or the antigen-binding fragment thereof and a vector containing the isolated polynucleotide of the present invention. Further provided in the present invention is the use of the antibody or the antigen-binding fragment thereof according to the present invention in the preparation of a drug, the drug being used for treating and/or preventing a disease that benefits from an enhanced immune response, wherein the disease is cancer.
Patent EP-4133576-A1 (EP)
Title: Moteur électrique submersible à flux axial
Inventor: SHETH KETANKUMAR KANTILAL
IPC: H02K5/132
Filed: 2021-03-11
Abstract: Un système de pompe pour pomper des fluides de production à partir d'un puits de forage ou pour pomper des fluides de traitement de puits dans un puits de forage comprend : un moteur électrique à flux axial ; une section d'étanchéité couplée au moteur à flux axial ; une admission de pompe couplée à la section d'étanchéité ; une pompe couplée à l'admission de pompe, et une évacuation de fluide couplée à la pompe. Le moteur à flux axial à capacité de couple peut être modifié sans retirer le moteur à flux axial de la pompe.
Patent EP-4133055-A1 (EP)
Inventor: HAY VIVIENNE
IPC: C12N1/12
Filed: 2021-04-12
Abstract: La présente technologie se rapporte globalement à une méthode de détermination de taux d'inclusion d'algues rouges dans des aliments pour bétail et dans des compléments pour bétail.
Patent EP-4221789-A1 (EP)
Title: A dose setting assembly for a medical injection device
Inventor: HUANG LONGXIANG
IPC: A61M5/315
Filed: 2021-09-29
Abstract: The dose setting assembly (10) for a medical injection device including a barrel (16) defining a reservoir (23) adapted to contain a medical injection fluid, an open proximal end and a distal end including a hub portion, a flange (18) disposed at the proximal end of said barrel (16), and an elongated plunger rod (17) having a plunger flange (25) at a proximal end and a stopper (22) a distal end, the plunger rod (17) being able to slidably move within the barrel (16), comprises : - a backstop attachable to the flange (18) of the barrel (16) and - a dose setting member secured on the backstop, configured to maintain the plunger rod in a predetermined position, the dose setting member being transversally removable from the backstop to authorize the plunger rod to move towards the backstop (11) and abuts onto said backstop (11).
Patent EP-4229064-A1 (EP)
Inventor: STOESSEL PHILIPP
IPC: C07F5/02
Filed: 2021-10-13
Abstract: L'invention concerne des composés cycliques qui peuvent être utilisés dans des dispositifs électroniques, ainsi que des dispositifs électroniques, en particulier des dispositifs électroluminescents organiques renfermant lesdits composés.
Patent EP-4136099-A1 (EP)
Inventor: PERREAULT CLAUDE
IPC: A61P37/04
Filed: 2021-03-15
Abstract: Acute myeloid leukemia (AML) has not benefited from innovative immunotherapies, mainly because of the lack of actionable immune targets. Novel tumor-specific antigens (TSAs) shared by a large proportion of AML cells are described herein. Most of the TSAs described herein derives from aberrantly expressed unmutated genomic sequences, such as intronic and intergenic sequences, which are not expressed in normal tissues. Nucleic acids, compositions, cells and vaccines derived from these TSAs are described. The use of the TSAs, nucleic acids, compositions, cells and vaccines for the treatment of leukemia such as AML is also described.
Patent EP-4139614-A1 (EP)
Title: Ice maker heater assemblies
Inventor: SMITH JERRY WAYNE
IPC: F25C5/08
Filed: 2021-04-05
Abstract: An ice maker includes an ice mold having an inner surface and an outer surface. The inner surface of the ice mold is configured to retain water for forming ice cubes in the ice mold. The ice mold includes a plurality of ice lobes each shaped to form a respective ice cube in the ice mold. A heater assembly is positioned on the outer surface of the ice mold. In some embodiments, each of a plurality of heating elements of the heater assembly is aligned with a corresponding lobe of the plurality of lobes for supplying heat to ice cubes formed in the lobes for releasing the ice cubes from the ice mold. In some embodiments, the heater assembly includes a heater having a ceramic substrate and one or more electrically resistive traces and electrically conductive traces thick film printed on the ceramic substrate.
Patent EP-4130327-A1 (EP)
Title: High-strength anti-collapse oil casing and manufacturing method therefor
Inventor: DONG XIAOMING
IPC: C22C38/26
Filed: 2021-05-06
Abstract: An anti-collapse oil casing with high strength and a manufacturing method therefor, comprising the following chemical elements in percentage by mass: C: 0.08%-0.18%; Si: 0.1%-0.4%; Mn: 0.1%-0.28%; Cr: 0.2%-0.8%; Mo: 0.2%-0.6%; Nb: 0.02%-0.08%b; V: 0.01%-0.15%; Ti: 0.02%-0.05%; B: 0.0015%-0.005%; and Al: 0.01%-0.05%. The manufacturing method for the anti-collapse oil casing with high strength comprises the steps of: (1) smelting and continuous casting; (2) perforating, rolling, and sizing; (3) controlled cooling: the initial cooling temperature being Ar3+50°C and the final cooling temperature being ≤80°C; the cooling step being performed only to the outer surface of the casing without performing to the inner wall of the casing; and the rate of the controlled cooling being 30-70°C/s; (4) tempering; and (5) thermal straightening. The anti-collapse oil casing with high strength according to the present invention has reasonable chemical composition and process design, which not only has excellent economic efficiency, but also has high strength, high toughness and high anti-collapse performance.
Patent EP-4137944-A1 (EP)
Title: Method and apparatus for displaying interaction message of application, and readable storage medium
Inventor: XU JIANNAN
IPC: G06F9/451
Filed: 2021-05-14
Abstract: A method and apparatus for displaying an interaction message of an application, and a readable storage medium. The method comprises: when a content viewing operation input by a user is received, displaying content corresponding to the content viewing operation for the user by means of a display interface of an application (APP) (S101); when an interaction message is received, displaying the interaction message within a preset area of the display interface (S 102); and when a first vertical sliding trigger operation with respect to the preset area is acquired, displaying a reply box on the display interface for the interaction message, so as to receive a reply message with respect to the interaction message (S103). By means of the method, when a user uses an APP to view content, and when an interaction message sent by another user is received, the interaction message is displayed in a preset area of a display interface so as to prompt the user, and the user can call a reply box, by means of a first vertical sliding operation, to reply, thus ensuring the timeliness and convenience of interaction between the users, without interrupting the user when normally viewing the current content, and thereby improving the user experience.
Patent EP-4247793-A1 (EP)
Inventor: JØRGENSEN MORTEN
IPC: C07D221/06
Filed: 2021-11-15
Abstract: The present invention provides sulfamate derivative prodrugs of the dopamine agonist (4aR,10aR)-1-Propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]quinoline-6,7-diol, their use in the treatment of conditions for which treatment with a dopamine agonist is therapeutically beneficial and pharmaceutical compositions comprising compounds of the invention. Compounds according to the invention are of formula (Id), wherein R1 and R2 are each independently selected from H, and substituent (iii) below, wherein * indicates the attachment point to oxygen, wherein R3 is selected from H and COR4, and wherein R4 is selected from H and C1-C6 alkyl, with the proviso that R1 and R2 cannot both be H,15 or a pharmaceutically acceptable salt thereof.
Patent EP-4163288-A1 (EP)
Title: Novel nucleolin-binding peptide and use thereof
Inventor: KIM JAEIL
IPC: A61K47/64
Filed: 2021-05-18
Abstract: The present invention relates to a novel peptide that specifically binds to nucleolin and, more specifically, to a peptide represented by a specific amino acid sequence, a conjugate comprising the peptide and an anticancer drug, a fusion peptide comprising the peptide and a cell-penetrating peptide, a composition for diagnosing cancer comprising the peptide, and a composition for preventing or treating cancer comprising the peptide or the conjugate. In the present invention, it has been confirmed that a peptide ligand AGM peptide and mutants thereof, as screened using an MAP synthesis method and an OBOC combination method, specifically bind to cancer cells, and a conjugate thereof with an anticancer drug inhibits cancer growth (in vitro and in vivo). Thus, the NCL-targeting AGM peptide can be effectively used for diagnosis and targeted drug delivery in cancer therapy.
Patent EP-4240954-A1 (EP)
Title: Fastening of an exhaust cone in a turbomachine nozzle
Inventor: JORET JEAN-PHILIPPE
IPC: F02K1/04
Filed: 2021-11-03
Abstract: The invention relates to an assembly for a turbine of a turbomachine having a longitudinal axis (X), comprising: -	an exhaust cone (100) comprising an annular outer wall (102) for a stream of a primary airflow and an annular chamber placed radially inside said annular outer wall (102), the annular chamber comprising an annular inner wall (104) placed radially inside the annular outer wall of the exhaust cone; -	an exhaust casing placed upstream of the exhaust cone; -	and a linking member (106) that is flexible in a radial direction and interposed longitudinally between the exhaust casing and the exhaust cone (100), the connecting member being fixed to the exhaust casing and to the annular inner wall (104), and wherein the annular inner wall (104) is connected to the annular outer wall (102) by fastening means (112) configured to enable displacements of the annular inner wall (104) in a circumferential direction and a longitudinal direction relative to the annular outer wall (102).
Patent EP-4260292-A1 (EP)
Title: Detection method for sample presence and device associated
Inventor: CARIGNANO ANDREA
IPC: G06V10/25
Filed: 2021-12-09
Abstract: Detection method for sample presence and device associated The invention relates to a detection method of liquid presence inside a well of a transparent or translucent support intended for analysis performed in a device for in vitro detection and/or quantification, the presence of liquid being assessed on the basis of an index of visible pattern likelihood representative of the probability of a pattern to be legible as expected in the field of view of an imager. Said invention allows preventing assay execution without sample and can be applied without wasting sample or sample well support in case of the sample well is not filled by the user. Moreover, this method allows a precise detection of the samples that are transparent or translucent, with low reflectance.
Patent EP-4141286-A1 (EP)
Inventor: TSUBAKINO KAZUYUKI
IPC: D06M15/564
Filed: 2021-07-01
Abstract: A power transmission belt (B) includes a belt body (11) made of an elastomer, and a cord (12) made of carbon fibers and embedded in the belt body (11). The belt tension To.z per 1 mm belt width at 0.2% of a belt extension rate is 70 N/mm or more. The belt tension T<sub>0.5</sub> per 1 mm belt width at 0.5% of the belt extension rate is 220 N/mm or more. The ratio of the belt tension T<sub>0.2</sub> to the belt tension T<sub>0.5</sub> is 0.33 or more.
Patent EP-4181591-A1 (EP)
Title: Positioning calibration method and device
Inventor: FAN HUIFANG
IPC: G01S19/05
Filed: 2021-07-09
Abstract: Embodiments of the present application provide a location calibration method and device. A terminal device first receives a location assistance message sent by a location server, where the location assistance message includes location calibration information. Then, the terminal device determines a target location calibration value corresponding to the terminal device in the location calibration information according to currently determined terminal location information, and calibrates the currently determined terminal location information based on the target location calibration value. In the embodiments of the present application, when the terminal device is located, the currently determined terminal location information of the terminal device is calibrated based on the location calibration information sent by the location server, whereby the location accuracy of the terminal device may be improved effectively.
Patent EP-4176292-A1 (EP)
Inventor: SCHUCK III MILLER HARRY
IPC: G02B5/04
Filed: 2021-07-02
Abstract: A method for measuring performance of a head-mounted display module, the method including arranging the head-mounted display module relative to a plenoptic camera assembly so that an exit pupil of the head-mounted display module coincides with a pupil of the plenoptic camera assembly; emitting light from the head-mounted display module while the head-mounted display module is arranged relative to the plenoptic camera assembly; filtering the light at the exit pupil of the head-mounted display module; acquiring, with the plenoptic camera assembly, one or more light field images projected from the head-mounted display module with the filtered light; and determining information about the performance of the head-mounted display module based on acquired light field image.
Patent EP-4263579-A1 (EP)
Inventor: BENFATTI FIDES
IPC: C07K14/435
Filed: 2021-12-21
Abstract: The present invention relates to a hexatoxin peptide variant comprising a. an amino acid sequence which is at least 90% identical to any one of SEQ ID NOs: 27 to 29, wherein the amino acid sequence has at least one amino acid variant on position N27; b. an amino acid sequence which is at least 90% identical to any one of SEQ ID NOs: 2, 6, 7, 30 or 32, wherein the amino acid sequence has at least one amino acid variant on position N28; c. an amino acid sequence which is at least 90% identical to any one of SEQ ID NOs: 1, 3, 4, 5, 8 to 24 or 31, wherein the amino acid sequence has at least one amino acid variant on position N29; d. an amino acid sequence which is at least 90% identical to SEQ ID NO: 25, wherein the amino acid sequence has at least one amino acid variant on position N30; e. an amino acid sequence which is at least 90% identical to SEQ ID NOs: 26, wherein the amino acid sequence has at least one amino acid variant on position N31; or f. an amino acid sequence which is at least 90% identical to SEQ ID NO: 34, wherein the amino acid sequence has at least one amino acid variant on position N32; each of which retain the biological activity of the hexatoxin; with the proviso that the peptide does not comprise the amino acid sequence of SEQ ID NO: 33.
Patent EP-4182355-A1 (EP)
Inventor: HOESLI CORINNE A
IPC: C07K16/18
Filed: 2021-07-14
Abstract: There is provided a surface functionalized with cross linking groups adapted to receive antibodies and/or fragments thereof. The surface has an antibody binding biomolecule having a linker region which is covalently crosslinked to functional groups and an antibody binding region. The surface also has a cell interacting biomolecule having a linker region which is covalently crosslinked to functional groups of the surface and a cell interacting region that imparts functional attributes including cell adhesion, spreading, proliferation, differentiation and/or a functional response. The two biomolecules are present in independently controlled concentrations and have similar small molecular weights.
Patent EP-4267250-A1 (EP)
Inventor: WANG KAILIANG
IPC: A61P35/00
Filed: 2021-12-21
Abstract: The present disclosure provides a compound of Formula (I) a pharmaceutically acceptable salt or a stereoisomer and their use in, e.g. treating a condition, disease or disorder in which the inhibition of the interaction of SOS 1 and a RAS -family protein or RAC1 is of therapeutic benefit, specifically in treating oncological diseases. This disclosure also features compositions containing the same as well as methods of using and making the same.
Patent EP-4256334-A1 (EP)
Inventor: BOYLE JEFF
IPC: G01N33/50
Filed: 2021-12-03
Abstract: Compositions and methods are provided for detection, diagnosis and prognosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) and for characterization of SARS-CoV-2 antigen-specific T-cell immune responsiveness in COVID-19 patient samples, including in secondary in vitro immune response assays for long-lived anamnestic (memory) T-cell responses. Disclosed compositions and methods include a method that comprises contacting, in vitro, whole blood samples from subjects suspected of having COVID-19 or who have previously been exposed to SARS-CoV-2, with synthetic peptides comprising T-cell epitope-containing regions derived from SARS-CoV-2 Spike proteins; and indirectly detecting SARS-CoV-2-specific activated T-cells by determining production of a T-cell immune response indicator (e.g., interferon-γ) in response to stimulation by the Spike protein-derived peptides.
Patent EP-4271563-A1 (EP)
Inventor: SPEGGIORIN LORENZO
IPC: B31B70/52
Filed: 2021-12-27
Abstract: The object of the invention is a packaging machine (10) for forming doy-pack bags, comprising: - a base (11); - a reel-holding frame (12), configured to carry a reel of packaging film or a sheet-holding reel (13) comprising a band with packaging sheets (14); - a gripping and folding group (15) configured to pick up and fold like a book, by facing two symmetrical parts (14a, 14b) thereof, either a portion of the packaging film or a packaging sheet (14); - shaping means for shaping a recessed bottom (B) of a doy-pack bag (A); - joining means (18, 118) for sealing the facing side edges (C1, C2, C3, C4) of the two symmetrical parts (14a, 14b) either of a portion of the packaging film or of a packaging sheet (14); - pick-up means (19) adapted to remove the portion of the packaging film or of the packaging sheet (14), folded and with the facing side edges (C1, C2, C3, C4) sealed, from the gripping and folding group (15).
Patent EP-4190352-A1 (EP)
Title: Formulation of novel bispecific anti-cd3/cd20 polypeptide complex
Inventor: ZHU YOUWEI
IPC: A61P35/00
Filed: 2021-07-26
Abstract: The present invention provides a novel bispecific anti-CD3/CD20 polypeptide complex formulation containing a first antigen-binding portion and a second antigen-binding portion. Specifically, the formulation comprises a liquid formulation and a lyophilized formulation.
Patent EP-4268426-A1 (EP)
Title: Methods for traffic redirection, corresponding terminal, controller, authorisation server, name resolution servers and computer program
Inventor: BOUCADAIR MOHAMED
IPC: H04L9/40
Filed: 2021-12-21
Abstract: The invention relates to methods for traffic redirection, corresponding terminal, controller, authorisation server, name resolution servers and computer program. The invention relates to a name resolution method, implemented in a terminal (51) connected to a communication network, which comprises: - transmitting (511), to a first name resolution server, a name resolution message via a secure communication channel between said terminal (51) and said first name resolution server, - if a redirection of the terminal's DNS traffic is authorised, obtaining (512) at least one identifier of a second name resolution server for said redirection, - executing (513) at least one action for managing said redirection of the terminal's DNS traffic to the second name resolution server, from among at least: - checking the legitimacy of said second name resolution server, - sending an indication of a failure of a connection of the terminal with said second name resolution server, - requesting the deactivation of said redirection of DNS traffic to said second name resolution server.
Patent EP-4202625-A1 (EP)
Title: Information processing device, information processing method, information processing program, and magnetic tape cartridge
Inventor: OISHI YUTAKA
IPC: G06F11/20
Filed: 2021-06-11
Abstract: An information processing apparatus performs a control of recording identification information of a storage pool in at least one of a management area of a magnetic tape belonging to the storage pool or a recording medium other than a magnetic tape that is provided in a magnetic tape cartridge including the magnetic tape, the storage pool being included in a plurality of storage pools in which the same data is recorded by being multiplexed with a multiplicity of one or more, and the identification information being different for each storage pool in a pool group and being the same information between storage pools in pool groups different from each other according to a multiplexing order of the storage pool.
Patent EP-4192484-A1 (EP)
Inventor: SEO JAE-GU
IPC: A61P37/08
Filed: 2021-02-26
Abstract: The present invention relates to a pharmaceutical composition effective for the prevention or treatment of atopic disease, the pharmaceutical composition containing a  Faecalibacterium prausnitzii  EB-FPDK11 strain or a culture or dried product thereof. While traditional probiotics generally have an insignificant therapeutic effect for atopic disease, the pharmaceutical composition of the present invention exhibits a preventive or therapeutic effect on atopic disease at the same level as that of steroid-based drugs, and thus is not only promising as pharmabiotics, but also useful in the development of food and cosmetics.
Patent EP-4120330-A1 (EP)
Title: Semiconductor edge processing apparatus and method
Inventor: WEN SOPHIA ZIYING
IPC: H01L21/67
Filed: 2021-09-14
Abstract: An apparatus for processing an edge surface of a wafer comprises a lower chamber having a first supporting area configured to support the wafer, an upper chamber having a second supporting area, and a first channel formed by the first supporting area, the second supporting area and peripheral areas thereof. The upper chamber is engaged with the lower chamber to position the wafer between the first supporting area and the second supporting area. The first channel is configured to provide a first space to flow one or more chemical fluids for etching an edge area of the wafer. The upper chamber comprises a protrusion part being configured to resist against an outer edge of the wafer in order to align the central axis of the wafer with the central axis of the second supporting area. This disclosure can process the edge of wafers.
Patent EP-4206957-A1 (EP)
Inventor: REN XIAOZHE
IPC: G06F17/16
Filed: 2021-09-18
Abstract: This application relates to the field of artificial intelligence, and provides a model training method. The method includes: obtaining a to-be-trained first neural network model, where the first neural network model includes a first operator, and the first operator is used to perform a product operation on input data and a target weight matrix (301); replacing the first operator in the first neural network model with a second operator, to obtain a second neural network model, where the second operator is used to perform a product operation on input data and a plurality of sub-weight matrices, and the plurality of sub-weight matrices are obtained by performing matrix factorization on the target weight matrix (302); and performing model training on the second neural network model to obtain a target neural network model (303). In this method, the target weight matrix is split into a product of the plurality of sub-weight matrices. Therefore, a training device requires a shorter time period to perform the product operation on the input data and the plurality of sub-weight matrices, thereby reducing a model training time period.