baber/WOPTO huggingface dataset:
Patent CZ-293127-B6 (CZ)
Title: 1,3-Dihydro-1-(phenylalkyl)-2H-imidazol-2-one derivatives exhibiting PDE IV and cytokine activity
Inventor: FREYNE EDDY JEAN EDGARD
IPC: C07D401/06
Filed: 1996-03-28
Abstract: The present invention describes the use of compounds for the manufacture of a medicament for treating warm-blooded animals suffering from disease states related to an abnormal enzymatic or catalytic activity of phosphodiesterase IV (PDE IV), and/or disease states related to a physiologically detrimental excess of cytokines, in particular allergic, atopic and inflammatory diseases, said compounds having formula (I), the N-oxide forms, the pharmaceutically acceptable acid or base addition salts and the stereochemically isomeric forms thereof, wherein Re1 and Re2 each independently represent a hydrogen atom; an alkyl,; difluoromethyl; trifluoromethyl; cycloalkyl; a saturated 5-, 6- or 7- membered heterocycle; indanyl; a bicyclic group;; alkylsulfonyl; arylsulfonyl; or substituted alkyl; Re3 denotes a hydrogen atom, halo or alkyloxy; Re4 represents a hydrogen atom; halo; optionally substituted alkyl; trifluoromethyl; cycloalkyl; carboxyl; alkyloxycarbonyl; cycloalkylaminocarbonyl; aryl; Hete1; or Re4 represents a radical of the general formula: -O-Re6; or -NH-Re7; Re5 denotes a hydrogen atom, halo, hydroxy or alkyl; or Re4 and Re5 taken together may form a bivalent radical; Y represents a direct bond, haloalkanediyl or alkanediyl; -A-B- denotes a bivalent radical of the general formula: -CRe9=CRe10-; or -CHRe9-CHRe10-; and L represents a hydrogen atom; optionally substituted alkyl; alkyloxycarbonyl; alkylsulfonyl or arylsulfonyl, whereby aryl can be optionally substituted. The present invention also relates to new compounds exhibiting PDE IV and cytokine inhibiting activity, processes for their preparation and compositions comprising said new compounds.
Patent CZ-288160-B6 (CZ)
Title: Pyrido[2,3-D]pyrimidines and pharmaceutical compositions based thereon
Inventor: BLANKLEY CLIFTON JOHN DR
IPC: A61K31/505
Filed: 1996-04-26
Abstract: In the present invention there are disclosed pyrido[2,3-D]pyrimidines of the general formula I in which the substituents have specific meanings, and pharmaceutically acceptable salts thereof. These compounds are suitable for inhibition of protein kinases and they are therefore effective for treating cell proliferative diseases, aterosclerosis, restenosis, psoriasis and cancer. In the present invention there are also claimed pharmaceutical compositions based on these compounds.
Patent CZ-294327-B6 (CZ)
Title: Multipurpose additive engine oil compositions and lubricating oil compositions
Inventor: AUER JANOS
IPC: C10N30/04
Filed: 1995-12-20
Abstract: The present invention relates to a multipurpose additive engine oil composition and engine lubricating oil composition comprising in addition to a base oil, 1.5 to 55 percent by weight of an additive mixture formed by the components "A", "B" and optionally "C" composed each of one or several additives, and they can further comprise a diluent. The component "A" of the additive mixture consists of /i/ a polyfunctional, ash-free additive composition exhibiting detergent-dispersive activity and formed by polymeric components prepared by reaction of a polyolefin derivative, preferably polyisobutylene derivative modified by interaction with one or several dicarboxylic acids and/or dicarboxylic acid anhydrides and with one or several vinyl co-monomers with compounds containing amino-, imino- or hydroxy-group, wherein the polyolefin chain supports on the average 1.6 to 20 acid groups and amount if its molecules having more than one acid group is greater than 25 percent by weight, whereby said derivative can be represented by imide, amide or ester amide and /ii/ a common alkenyl derivative of succinic acid, such as imide, ester or ester amide. The component "B" of the additive mixture consists of one or several current additives, such as detergents-dispersants, antioxidants, friction modifiers, abrasion-resistant additives, corrosion inhibitors, foam generation reducing additives and solidification point reducing additives, whereby the component "C" of the additive mixture consists of one or several current modifiers of viscosity index improvers.
Patent SK-282545-B6 (SK)
Title: Crystalline additive cephem salts with acids, their production me thod, their use and medicament containing them
Inventor: LATTRELL RUDOLF
IPC: C07D501/00
Filed: 1995-11-08
Abstract: Disclosed are compounds of general formula (I), wherein n is equal 1 or 2 and m is equal 0.4 to 2.6, whilst X is anion of some phenolic carboxylic acid, the meaning of which is stated in the description. Disclosed is also their production method, medicament containing them and their use for production of medicaments for treatment of bacterial infections.
Patent SK-283405-B6 (SK)
Title: Instant vesicular product
Inventor: MOLLEE HINDERIKUS MARIUS
IPC: A61K9/127
Filed: 1997-05-12
Abstract: A powder of reversed vesicles, which comprises one or more non-ionic surfactants and optionally a lipophilic stabilising factor and a bioactive agent, is provided. The product is prepared by making a dispersion of reversed vesicles in a suitable apolar vehicle, which vehicle is subsequently removed. In admixture with one or more excipients the product can be incorporated in compositions.
Patent SK-282412-B6 (SK)
Inventor: THOMPSON ANDREW S
IPC: C07D265/18
Filed: 1996-05-21
Abstract: Spôsob syntézy vysoko účinného inhibítora reverznej transkriptázy HIV (A) využívajúci acetylid a trifluórmetylketón, ktorým vzniká chirálny produkt v prítomnosti chirálneho aminoalkoholu.ŕ
Patent SK-279970-B6 (SK)
Title: Method for the preparation of 2-perfluoroalkyl-3-oxazolin-5-one, and perfluoroalkanoyl aminonitrile compounds
Inventor: KAMESWARAN VENKATARAMAN
IPC: C07D307/54
Filed: 1994-12-21
Abstract: A method for the preparation of compounds of the general formula (II), wherein n is an integer of 1 - 8, the meaning of an R substituent is stated in the Description, is processed by reacting an aminonitrile with a perfluoroacylating agent in the presence of a solvent or, optionally, in the presence of a base. A perfluoroalkanoyl aminonitrile thus obtained is subjected to cyclizing in the presence of an acid and at least one molar equivalent of water.
Patent SK-278479-B6 (SK)
Title: Thermoplastic pipe for guiding of cables for cable guiding device
Inventor: VOGELSANG HORST
IPC: H02G1/08
Filed: 1992-07-08
Abstract: The pipe (2) made based on the thermoplastic material used for guiding of cables closed to the equip,emt for guiding of cables (4) has the channel (4) with an annular section for guiding of cables and the internal wall with sliding ribs (5) passing in a parallel direction to each other. The sliding parts have the areas with a screw direction guidance with an opposite pitch, having a wave shape, after an internal wall of the channel (4) is being expanded. The length (L) of waving value is in the interval of 80 up to 160 cm and the amplitude (A) of the waves is less than one fourth closed to the internal circuit of the channel (4) used for guiding of cables.
Patent SK-278097-B6 (SK)
Title: Device for dimensional adjustment of laying of axled springs, on hollow axle of double-wheels and parallel position securing of distribution of  double-wheels of driving undercarriage of track vehicles
Inventor: LACHMANN KLAUS
IPC: B61F5/26
Filed: 1992-12-11
Abstract: Over every side of double-wheels (1) is located the centric elements (6,6') simulating the elastic laying of double-wheels (1) for equalizing of string bearings (4,4a) at which every centric element (6,6') is created with left and right centric element (6a,6b) if stick form and every centric element (6a,6b) is firmly holded by holder (5). The centric elements (6,6') are mutually firmly connected with connecting beam (7) in area over distribution (2) and with connecting beam (7) is in area over distribution (2) firmly connected also triangle beam rectangle beam (8) which is equipped in own lower area in height of outlet flange (2a) of distribution (2) with adjustable centric mechanism (9) for adjustment of position of outlet flange (2a) of distribution (2).
Patent SK-278897-B6 (SK)
Title: Method for producing 3,7-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro- -1h-purine
Inventor: GOMORY JURAJ
IPC: C07D473/06
Filed: 1990-10-26
Abstract: This invention solves the procedure closed to the production of 3,7-dimethyl-2,6 -dioxo-1,2,3,6-tetrahydro-1H-purine based on the reaction of 3-methyl-2,6-dioxo-1,2,3-tetrahydro-1,7H-purine or its salts with dimethylcarbonate in the reaction environment created based on solvent and this solvent can be represented by excess of dimethylcarbonate or by another suitable organic solvent, while dimethylformamide is suitable and this reaction is provided at the temperature of 50 Celsius degrees up to the boiling temperature of this solvent. This reaction is taking place when the suitable is or is not present and in the case of free compound application (see also formula II), and this agent is selected of the group with organic, inorganic basis, or inorganic oxides, while the catalyst is or is not present, while this catalyst is a phase transmission catalyst, while triethylbenzylammonium chloride is suitable. This invention can be applied in a chemical and pharmaceutical industry.
Patent CZ-283495-B6 (CZ)
Inventor: KACHER MARK LESLIE
IPC: C11D1/04
Filed: 1991-11-20
Abstract: Jsou popsány tvarové předměty, zvláště předměty  z čisticích materiálů, obsahující kostru  tvořenou poměrně tuhou, vzájemně propletenou  síti solí monokarboxylových a dikarboxylových  kyselin a způsob jejich přípravy krystalizací  vodné taveniny těchto solí karboxylových kyselin  ve formě.ŕ
Patent CZ-296662-B6 (CZ)
Title: Disposable absorbent sanitary aid
Inventor: MALOWANIEC KRZYSZTOF DANIEL
IPC: A61F13/15
Filed: 1998-07-28
Abstract: The present invention relates to a disposable absorbent sanitary aid, comprising a liquid-tight back sheet (4), a liquid-permeable cover sheet (2), an absorbent body (6) containing super-absorbent polymer materials, which is suitable for storing bodily fluids, especially urine, and which is located between said back sheet (4) and said cover sheet (2), and a two-layer intermediate part (8) which takes up and distributes liquid. Said intermediate part (8) is made up of a top layer (18) consisting of synthetic fibers and a bottom layer (20), the average pore volume of the top layer (18) being greater than the average pore volume of the bottom layer (20), and is arranged between the absorbent body (6) and the cover sheet (2). The inventive sanitary aid is configured in such a way that the bottom layer (20) is made essentially exclusively of chemically cross-linked cellulose fibers and the top layer (18) overlaps the longitudinal ends (21) of the bottom layer (20) with its longitudinal edge sections (19) so that the hygiene item is able to absorb more than one of loss of liquid and give the wearer a feeling of dryness. The cross-linked cellulose fibers of the bottom layer (20) are also more hydrophilic than the synthetic fibers of the top layer (18) of the intermediate part (8).
Patent CZ-302668-B6 (CZ)
Title: Pharmaceutical composition containing 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)-ethoxy]benzyl]thiazolidine-2,4-dione and use thereof
Inventor: BUCKINGHAM ROBIN EDWIN
IPC: A61K31/17
Filed: 1998-07-16
Abstract: In the present invention, there is described a pharmaceutical composition containing 2 to 8 mg of 5-[4-[2-(N-methyl-N-(2pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione that means the compound of the general formula (I) or a pharmaceutically acceptable derivative thereof, submaximal amount of composition for support of insulin secretion being selected from the group consisting of glibenclamide, glipizide, gliclazide and glimepiride, and a pharmaceutically acceptable carrier. There is also described the use of the above-indicated composition.
Patent CZ-299717-B6 (CZ)
Title: Process for preparing modified alkylbenzenesulfonate surfactants
Inventor: SCHEIBEL JEFFREY JOHN
IPC: C09K23/12
Filed: 1998-08-04
Abstract: In the present invention, there is disclosed a process for preparing modified alkylbenzenesulfonate surfactants comprising : (A) a stage of at least partially separating a hydrocarbon feed being selected from the group consisting of olefin feed, paraffin feed and mixtures thereof, wherein said hydrocarbon feed comprises branched aliphatic hydrocarbons having from 8 to 20 carbon atoms, into - at least one branched-enriched stream comprising an increased proportion of branched acyclic hydrocarbons relative to said hydrocarbon feed and optionally, one or more of - a linear-enriched stream comprising an increased proportion of linear aliphatic hydrocarbons relative to said hydrocarbon feed ; and - a reject stream comprising cyclic and/or aromatic and/or ethyl- or higher-branched hydrocarbons ; wherein said stage (A) comprises : - providing said hydrocarbon feed ; and - adsorptive separation of said feed into said streams using porous media ; said stage (A) using simulated moving bed adsorptive separation means comprising both of - at least one bed holding said porous media ; and - a device for simulating motion of said porous media countercurrent to a hydrocarbon stream in said bed ; (B) (i) at least partially dehydrogenating the branched-enriched stream of stage (A) thereby forming an olefinic branched-enriched stream comprising mono-olefin, optionally followed by one or more of (ii) treating said olefinic branched-enriched stream to diminish the content therein of diolefin impurities and (iii) treating said olefinic branched-enriched stream to diminish the content therein of aromatic impurities ; (C) optionally, at least partially concentrating said mono-olefins in said olefinic branched-enriched stream of stage (B) by means of sorptive separation using a known sorbent or porous media provided that said sorbent or porous media are nonidentical with the porous media of stage (A) and are adapted for olefin/paraffin separations and, optionally, concurrently recycling paraffins to said dehydrogenation stage (B); and (D) reacting said olefinic branched-enriched stream produced in stage (B) or, optionally, as further concentrated in stage (C), with carbon monoxide and hydrogen in the presence of an OXO catalyst, thereby forming a modified primary OXO alcohol.
Patent CZ-305313-B6 (CZ)
Title: Reinforced structural part
Inventor: HASL PAUL
IPC: B62D29/04
Filed: 2010-09-17
Abstract: In the present invention, there is disclosed a reinforced structural part (1, 1´) consisting of at least one plastic section (2, 3) reinforced at least in sections of the external walls (4, 5) thereof by longitudinal reinforcing elements (6), oriented in the direction of the longitudinal axis (A) of the plastic section (2, 3). The plastic sections (2, 3) comprise lower surface (10, 11) with two longitudinal side surfaces (12, 13) and two transverse side surfaces (14, 15) provided at their upper edges with peripheral flanged surfaces (9) for possibility of their mutual connection to the form of a closed box section. The reinforcing elements (6) of the plastic sections (2, 3) are formed by metal wires with surface shaping (7) serving for anchorage thereof allover their length into the plastic section (2, 3) material and for capture of tension forces in case of loading thereof by bending.
Patent CZ-304434-B6 (CZ)
Title: Surface treatment method of aggregates for enhancing resistance of refractory concretes against the action of carbon extracted from a body
Inventor: PTÁČEK PETR
IPC: C04B35/03
Filed: 2013-03-14
Abstract: In the present invention, there is described a surface treatment method of aggregates for refractory concretes by a milk-of lime suspension prepared by the use of lime, magnesium lime or half-burnt magnesium lime (a mixture of MgO and CaCOi3). Through subsequent calcination at a temperature of at least 1100 degC for a period of at the most 2 hours a layer of a hard calcined lime is formed on the surface of the aggregate grain. An intermediate layer with a composition and thickness depending on the composition of aggregates, a lime used in the preparation of the milk-of lime suspension, temperature and time of calcination is created below the surface layer. Depending on chemical nature and thickness of the formed surface layer, aggregates treated by the method according to the present invention exhibit an enhanced resistance against the action of carbon and iron eutectic hot melts extracted from a body. Therefore, they can be used for the preparation of loose refractory building materials and mixtures thereof, shotcrete mixtures, repair mixtures, mortars and refractory monoliths.
Patent CZ-305772-B6 (CZ)
Title: Method of monitoring changes in earth lithosphere and atmosphere and apparatus for making the same
Inventor: JÍLEK KAREL
IPC: G01V1/28
Filed: 2014-06-29
Abstract: The invented method of monitoring changes in earth lithosphere and atmosphere, particularly for the purpose of earthquake forecast, is characterized in that in independent measuring modules, there is carried out measurement of variables, being selected from the group consisting of: - radon and/or thoron volume activity in the atmosphere, - volume activity of the radon and thoron daughter products in the atmosphere, - volume activity of radon and thoron in lithosphere, - volume activity of radon in lithosphere waters, and the measurement results are transmitted to a central unit (1) or a computer (6). Subsequently, a measurement profile curve is then created from the values of the selected variables being measured within a time interval in that interval, the measurement profile curves are then arranged in a sequential time series and increments of surfaces below the measurement profile curves if the same time series are compared with each other or with the increment of a priority variable selected from the measured variables. Apparatus for monitoring changes in earth lithosphere and atmosphere comprises independent measuring modules (A, B, C, F) to measure variables of natural radioactivity being selected from the group of the above-indicated modules and/or a module (F) for measuring radon volume activity pro in lithosphere waters and a central unit (1) or a computer (6) with control and evaluation software for – synchronization of time periods of the measurements and – evaluation of the measured values of the selected variables.
Patent CZ-309780-B6 (CZ)
Title: A magnetic modular block
Inventor: VIKHROV IGOR
IPC: A63H33/04
Filed: 2022-05-24
Abstract: The cube-shaped magnetic modular block equipped with magnets (2) is assembled from six identical square flat parts (1), the inner surface (12) of which is bounded by raised edge rims (11) equipped with inner edges (111). On the half of each side of the part (1), parallel to this side, a cut-out (13) is created, the end corner part of which is provided with a magnetic bed (14) for storing the ball magnet (2), wherein, in the region of the cut-out (13), a catch (15) provided with a tooth (151) directed outside the surface of the part (1) parallel to its wall is formed on the rim (11) in a direction perpendicular to the surface of the part (1).
Patent SK-286090-B6 (SK)
Title: Working tool with replaceable working bit
Inventor: SKJAEVELAND MAGNE
IPC: A01B/
Filed: 2001-01-31
Abstract: A replaceable wear part (13, 22, 22a, 32, 41) for mounting on a leading edge (12) of a working tool (10, 27, 30), said leading edge and said wear part having co-operative guide formations (16, 18) extending generally perpendicular to the leading edge and which provide a socket and projection type of slidable inter-fit whereby the wear part can be driven by a force extending generally perpendicular to the leading edge in order to take-up a working position in which it is secured against displacement from the working position by frictional inter-engagement between the guide formations (16, 18) on the wear part and the leading edge, and without need for threaded or other separate removable fasteners.
Patent SK-286773-B6 (SK)
Title: Benzoimidazole derivatives, their use and pharmaceutical compositions comprising said compounds
Inventor: BARTH WAYNE ERNEST
IPC: A61K31/00
Filed: 2000-11-10
Abstract: The invention relates to benzoimidazole compounds of formula (I) and to pharmaceutically acceptable salts, prodrugs and solvates thereof and to the use of them for producing medicaments for treating abnormal cell growth, such as cancer, in mammals and to pharmaceutical compositions which contain these compounds.
Patent SK-287961-B6 (SK)
Title: Floorboard and locking system
Inventor: PERVAN DARKO
IPC: E04F15/00
Filed: 2002-01-14
Abstract: A floorboard and an openable locking system therefor comprise an undercut groove (36) on one long side of the floorboard and a projecting tongue (38) on the opposite long side of the floorboard. The undercut groove (36) has a corresponding upwardly directed inner locking surface at a distance from its tip. The tongue (38) and the undercut groove (36) are formed to be connected by adjoining boards being brought together and snapped together.
Patent CZ-288573-B6 (CZ)
Title: Device for bulk metering of small half-finished products
Inventor: ANTONIN LUBOS ING
IPC: G01F11/18
Filed: 2000-05-15
Abstract: The proposed device for bulk metering of small half-finished products (11) is formed by metering strips (2) having recesses beds (14) and inserted in a plate (1) that is coupled with an air cylinder (6). Above the plate, (1) there is placed a magazine (3) of half-finished products (11) with open bottom section (10). The plate (1) is fixedly coupled with a table (4) disposed between stops (7) and mounted in a sliding or rolling linear guide (5). The guide (5) is attached to a rider (8) of a magnetic air cylinder (9) mounted in a frame (12) and inclined under an angle with respect to horizontal plane. The frame (Q12) is provided with resilient stops (13).
Patent CZ-295079-B6 (CZ)
Title: Friction rock bolt
Inventor: PALONCY LIBOR ING
IPC: E21D21/00
Filed: 2000-10-05
Abstract: The present invention relates to a friction rock bolt the anchor portion of which is formed by one or several rods (1) of solid section and an expanding element (2) abutting parallel to these rods (1) for their pressing against a borehole (13) wall. Said expanding element (2) is formed for example by a thin-walled expansion tube (3) with distorted cross section in the form of a longitudinal groove intended for placing therein each rod (1).
Patent CZ-301233-B6 (CZ)
Title: Fungicidal combinations of active substances, method of fighting fungi and use of such combinations of the active substances and process for preparing fungicidal agents
Inventor: WACHENDORFF-NEUMANN ULRIKE
IPC: A01N43/36
Filed: 2000-11-30
Abstract: The present invention relates to novel combinations of fungicidal active substances of so far known fluorobenzothiazole derivative of the general formula (I) on one side and other so far known active substances of the groups (1) to (42), whereby said groups are mentioned in the description on the other side, which are very suitable for fighting phytopathogenic fungi. The invention further relates to a method of fighting fungi and fungicidal agents in which the above-indicated compounds are comprised.